Bioconductor Affymetrix Probe Listing

Probe	log2FC	AveExpr	t	P.Value	adj.P.Val	B	Symbol	Description	Chromosome	Chromosome Location	GenBank	Gene	Cytoband	UniGene	PubMed	Gene Ontology	Pathway
209005_at	0.982	7.759	10.038	4.174e-08	0.001	7.804	FBXL5	F-box and leucine-rich repeat protein 5	4	-15215251	AF157323	26234	4p15.32	Hs.643433	13	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process
228044_at	0.956	5.006	10.029	4.224e-08	0.001	7.796	SERP2	stress-associated endoplasmic reticulum protein family member 2	13	43845977	AI420319	387923	13q14.11	Hs.377972	4	endoplasmic reticulum protein transport membrane integral to membrane intracellular protein transmembrane transport
209075_s_at	-1.031	11.329	-9.922	4.874e-08	0.001	7.693	ISCU	iron-sulfur cluster scaffold homolog (E. coli)	12	107480423	AY009128	23479	12q24.1	Hs.615131	14	iron ion binding nucleus cytoplasm mitochondrion cytosol nitrogen fixation iron-sulfur cluster assembly protein complex scaffold metal ion binding iron-sulfur cluster binding
242414_at	1.305	5.714	9.460	9.153e-08	0.001	7.232	QPRT	quinolinate phosphoribosyltransferase	16	29597941	AW960707	23475	16p11.2	Hs.513484	8	nicotinate-nucleotide diphosphorylase (carboxylating) activity nicotinate-nucleotide diphosphorylase (carboxylating) activity cellular_component cytosol metabolic process NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process quinolinate catabolic process protein homodimerization activity protein oligomerization	Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
224323_s_at	1.032	5.975	9.237	1.251e-07	0.001	6.999	MRO	maestro	18	-46575487, -46575487	AB042647	83876	18q21	Hs.30495	6	binding nucleus nucleolus
225817_at	0.912	4.119	8.153	6.183e-07	0.004	5.769	CGNL1	cingulin-like 1	15	55455996	AB051536	84952	15q21.3	Hs.148989	6	motor activity tight junction myosin complex cell junction
204044_at	1.358	5.567	8.109	6.616e-07	0.004	5.715	QPRT	quinolinate phosphoribosyltransferase	16	29597941	NM_014298	23475	16p11.2	Hs.513484	8	nicotinate-nucleotide diphosphorylase (carboxylating) activity nicotinate-nucleotide diphosphorylase (carboxylating) activity cellular_component cytosol metabolic process NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process quinolinate catabolic process protein homodimerization activity protein oligomerization	Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
217963_s_at	1.534	8.334	8.072	6.998e-07	0.004	5.671	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	X	102517923, 102518764	NM_014380	27018	Xq22.2	Hs.448588 Hs.719133	17	protein binding nucleus cytoplasm apoptosis multicellular organismal development metal ion binding	Neurotrophin signaling pathway
224324_at	0.907	5.004	8.045	7.297e-07	0.004	5.638	MRO	maestro	18	-46575487, -46575487	AB042647	83876	18q21	Hs.30495	6	binding nucleus nucleolus
1557260_a_at	1.608	2.670	7.978	8.097e-07	0.004	5.555	ZNF382	zinc finger protein 382	19	41788060	BM973530	84911	19q13.12	Hs.631591	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201462_at	1.101	4.520	7.537	1.631e-06	0.006	4.992	SCRN1	secernin 1	7	-29926244, -29926244, -29926244	NM_014766	9805	7p14.3-p14.1	Hs.520740	11	molecular_function nucleus cytoplasm exocytosis nuclear membrane
227558_at	1.060	6.002	7.503	1.723e-06	0.006	4.947	CBX4	chromobox homolog 4 (Pc class homolog, Drosophila)	17	-75421549	AI570531	8535	17q25.3	Hs.714363	25	chromatin chromatin binding transcription corepressor activity nucleus chromatin assembly or disassembly anti-apoptosis negative regulation of transcription chromatin modification enzyme binding modification-dependent protein catabolic process
222431_at	1.036	6.362	7.458	1.854e-06	0.006	4.888	SPIN1	spindlin 1	9	90193116	AL136719	10927	9q22.1-q22.3	Hs.146804	16	nucleus spindle cell cycle multicellular organismal development gamete generation
210091_s_at	-0.896	7.854	-7.432	1.937e-06	0.006	4.852	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U46745	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
239035_at	0.625	6.290	7.417	1.983e-06	0.006	4.833	MTHFR	5,10-methylenetetrahydrofolate reductase (NADPH)	1	-11768373	AL138431	4524	1p36.3	Hs.214142	1776	methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction	One carbon pool by folate Methane metabolism Metabolic pathways
219765_at	2.048	4.909	7.391	2.068e-06	0.006	4.799	ZNF329	zinc finger protein 329	19	-63329506	NM_024620	79673	19q13.43	Hs.458377	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
204270_at	0.638	6.165	7.319	2.327e-06	0.007	4.702	SKI	v-ski sarcoma viral oncogene homolog (avian)	1	2149993	AI568728	6497	1q22-q24	Hs.663133	54	nucleotide binding protein binding nucleus nucleoplasm cell differentiation BMP signaling pathway
1555310_a_at	0.775	5.885	7.094	3.380e-06	0.009	4.394	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	15	38296920, 38319326	BC035596	56924	15q14	Hs.513645	13	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
1558486_at	1.031	5.671	6.849	5.123e-06	0.012	4.049	ZNF493	zinc finger protein 493	19	21371760, 21371760	BC022394	284443	19p12	Hs.656558	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
204309_at	0.666	4.458	6.748	6.084e-06	0.013	3.905	CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	15	-72417155, -72417155	NM_000781	1583	15q23-q24	Hs.303980	88	monooxygenase activity mitochondrion lipid metabolic process C21-steroid hormone biosynthetic process cholesterol metabolic process cholesterol metabolic process cholesterol monooxygenase (side-chain-cleaving) activity cholesterol monooxygenase (side-chain-cleaving) activity electron carrier activity membrane heme binding mitochondrial membrane vitamin D metabolic process metal ion binding oxidation reduction	C21-Steroid hormone metabolism Metabolic pathways
239763_at	0.536	5.742	6.589	8.020e-06	0.015	3.672	PRDM11	PR domain containing 11	11	45072139	AA157112	56981	11p11	Hs.178715	3
230919_at	1.033	3.345	6.585	8.068e-06	0.015	3.667	ZNF233	zinc finger protein 233	19	49455915	AW006620	353355	19q13.31	Hs.466891	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
236328_at	0.690	4.744	6.565	8.368e-06	0.015	3.637	ZNF285A	zinc finger protein 285A	19	-49581647	AW513227	26974		Hs.709428	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
223016_x_at	-0.979	7.617	-6.533	8.837e-06	0.016	3.590	ZRANB2	zinc finger, RAN-binding domain containing 2	1	-71301561	AF065392	9406	1p31	Hs.194718	18	transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding
205311_at	1.014	4.213	6.518	9.076e-06	0.016	3.568	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7	-50493627, -50493627	NM_000790	1644	7p12.2	Hs.359698	48	aromatic-L-amino-acid decarboxylase activity protein binding cellular amino acid and derivative metabolic process response to toxin lyase activity carboxylic acid metabolic process pyridoxal phosphate binding catecholamine biosynthetic process	Histidine metabolism Tyrosine metabolism Phenylalanine metabolism Tryptophan metabolism Isoquinoline alkaloid biosynthesis Betalain biosynthesis Biosynthesis of alkaloids derived from shikimate pathway Metabolic pathways
209004_s_at	0.712	10.040	6.356	1.209e-05	0.020	3.325	FBXL5	F-box and leucine-rich repeat protein 5	4	-15215251	AF142481	26234	4p15.32	Hs.643433	13	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process
201860_s_at	0.829	5.248	6.314	1.302e-05	0.021	3.261	PLAT	plasminogen activator, tissue	8	-42151392	NM_000930	5327	8p12	Hs.491582	209	serine-type endopeptidase activity extracellular region extracellular region extracellular space protein modification process proteolysis blood coagulation peptidase activity	Complement and coagulation cascades
212168_at	-0.696	5.686	-6.243	1.476e-05	0.023	3.154	RBM12	RNA binding motif protein 12	20	-33700292	AL514547	10137	20q11.21	Hs.246413	13	nucleotide binding RNA binding protein binding nucleus
207757_at	0.783	4.480	6.059	2.060e-05	0.030	2.868	ZFP2	zinc finger protein 2 homolog (mouse)	5	178255521	NM_030613	80108	5q35.3	Hs.654533	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
219073_s_at	1.405	4.964	6.049	2.096e-05	0.030	2.854	OSBPL10	oxysterol binding protein-like 10	3	-31677320	NM_017784	114884	3p22.3	Hs.150122	7	lipid transport steroid metabolic process
238049_at	0.711	3.958	5.985	2.358e-05	0.033	2.752	GRAMD3	GRAM domain containing 3	5	125723686, 125786767, 125828685	AW971198	65983	5q23.2	Hs.363558	6
240744_at	0.888	5.173	5.967	2.433e-05	0.033	2.725	CPA5	carboxypeptidase A5	7	129771865, 129771865	AW184014	93979	7q32	Hs.567642	9	metallocarboxypeptidase activity extracellular region proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
219109_at	1.008	6.414	5.938	2.570e-05	0.033	2.678	SPAG16	sperm associated antigen 16	2	213857360, 213857360	NM_024532	79582	2q34	Hs.602792 Hs.715620	6	cytoplasm cilium flagellum cell projection organization
223192_at	0.551	8.030	5.883	2.841e-05	0.035	2.591	SLC25A28	solute carrier family 25, member 28	10	-101360264	AF267854	81894	10q23-q24	Hs.403790	6	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
229160_at	-1.273	7.231	-5.810	3.253e-05	0.037	2.474	MUM1L1	melanoma associated antigen (mutated) 1-like 1	X	105307974	AI967987	139221	Xq22.3	Hs.592221	5
227379_at	0.791	5.055	5.772	3.487e-05	0.037	2.414	MBOAT1	membrane bound O-acyltransferase domain containing 1	6	-20208913	AI734993	154141	6p22.3	Hs.377830	7	acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
205591_at	-0.782	6.013	-5.757	3.587e-05	0.037	2.389	OLFM1	olfactomedin 1	9	137106909, 137106923	NM_006334	10439	9q34.3	Hs.522484	9	protein binding endoplasmic reticulum endoplasmic reticulum lumen multicellular organismal development nervous system development membrane
226548_at	0.639	7.623	5.744	3.675e-05	0.037	2.368	SBK1	SH3-binding domain kinase 1	16	28211340	AI935915	388228	16p11.2	Hs.97837	3	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
201904_s_at	1.178	6.793	5.718	3.852e-05	0.037	2.327	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF031714	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
222628_s_at	0.539	7.225	5.718	3.858e-05	0.037	2.326	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	AA195405	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
228084_at	0.819	7.162	5.716	3.873e-05	0.037	2.322	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AI767751	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
238047_at	3.763	5.314	5.692	4.049e-05	0.037	2.284	RP13-102H20.1	hypothetical protein FLJ30058	X	130019896	AA405456	158763	Xq26.1	Hs.22905	5	intracellular signal transduction
219015_s_at	-0.799	4.438	-5.686	4.090e-05	0.037	2.275	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_018466	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
220183_s_at	0.785	6.738	5.665	4.258e-05	0.038	2.240	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	4	-124033248, -124033248	NM_007083	11162	4q26	Hs.558459	15	cellular_component growth factor activity biological_process hydrolase activity
203423_at	1.720	6.369	5.652	4.359e-05	0.038	2.220	RBP1	retinol binding protein 1, cellular	3	-140727937, -140727317, -140718965	NM_002899	5947	3q23	Hs.529571	31	transporter activity cytoplasm transport lipid binding retinal binding retinol binding retinol metabolic process retinoic acid metabolic process
215307_at	0.639	3.799	5.640	4.458e-05	0.038	2.200	ZNF529	zinc finger protein 529	19	-41762996, -41726357, -41726357	AL109722	57711	19q13.13	Hs.708146	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1564190_x_at	0.680	4.303	5.634	4.509e-05	0.038	2.190	ZNF519	zinc finger protein 519	18	-14094723	AK096748	162655	18p11.21	Hs.352635	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
232932_at	0.563	5.416	5.630	4.542e-05	0.038	2.184	LOC645030	hypothetical protein LOC645030	1		AU145140	645030	1p31.3	Hs.632410
215554_at	0.947	5.133	5.626	4.580e-05	0.038	2.176	GPLD1	glycosylphosphatidylinositol specific phospholipase D1	6	-24581304, -24536383	AV699786	2822	6p22.3-p22.2	Hs.533291	26	glycosylphosphatidylinositol phospholipase D activity extracellular region hydrolase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
204400_at	0.654	4.839	5.576	5.034e-05	0.040	2.094	EFS	embryonal Fyn-associated substrate	14	-22895450	NM_005864	10278	14q11.2-q12	Hs.24587	8	cytoplasm cell adhesion intracellular signaling cascade SH3 domain binding
210611_s_at	-1.077	6.975	-5.573	5.061e-05	0.040	2.089	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U26744	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
222975_s_at	-0.728	10.872	-5.529	5.492e-05	0.042	2.018	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	AI423180	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
200998_s_at	0.577	6.621	5.526	5.531e-05	0.042	2.012	CKAP4	cytoskeleton-associated protein 4	12	-105155789	AW029619	10970	12q23.3	Hs.714862 Hs.74368	22	membrane fraction endoplasmic reticulum membrane integral to membrane
210807_s_at	0.844	4.907	5.508	5.722e-05	0.042	1.982	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	AF049608	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
228332_s_at	-0.423	9.953	-5.501	5.790e-05	0.042	1.972	C11orf31	chromosome 11 open reading frame 31	11	57265297	AA526939	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
207236_at	0.624	4.598	5.481	6.019e-05	0.043	1.938	ZNF345	zinc finger protein 345	19	42033106	NM_003419	25850	19q13.12	Hs.362324	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity RNA polymerase III transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase III promoter zinc ion binding regulation of transcription metal ion binding
212915_at	-1.274	9.177	-5.464	6.212e-05	0.044	1.910	PDZRN3	PDZ domain containing ring finger 3	3	-73514341	AL569804	23024	3p13	Hs.719126	9	protein binding zinc ion binding metal ion binding
224928_at	-0.733	9.894	-5.446	6.430e-05	0.045	1.880	SETD7	SET domain containing (lysine methyltransferase) 7	4	-140646641	AK024846	80854	4q28	Hs.480792	21	protein binding nucleus chromosome regulation of transcription, DNA-dependent methyltransferase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity	Lysine degradation
217551_at	0.686	3.983	5.439	6.519e-05	0.045	1.868	LOC441453	similar to olfactory receptor, family 7, subfamily A, member 17	11		AA719797	441453	11p15.1	Hs.523504	1
226592_at	0.530	5.056	5.430	6.635e-05	0.045	1.852	ZNF618	zinc finger protein 618	9	115678382	AA031404	114991	9q32	Hs.349208	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity
223680_at	0.496	3.733	5.424	6.708e-05	0.045	1.843	ZNF607	zinc finger protein 607	19	-42879115	BC005085	84775	19q13.1	Hs.116622	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
243924_at	1.088	3.740	5.398	7.042e-05	0.045	1.800	LOC100127980	hypothetical protein LOC100127980	19		AA781404	100127980	19q13.12	Hs.595153	1
244428_at	0.521	4.351	5.394	7.103e-05	0.045	1.793	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	2	-25357824, -25309348, -25309348, -25309348	AW572279	1788	2p23	Hs.515840	54	euchromatin DNA binding DNA (cytosine-5-)-methyltransferase activity protein binding nucleus cytoplasm DNA methylation genetic imprinting methyltransferase activity zinc ion binding nuclear matrix transferase activity metal ion binding	Cysteine and methionine metabolism Metabolic pathways
239093_at	0.802	4.587	5.372	7.398e-05	0.045	1.757	DHDPSL	dihydrodipicolinate synthase-like, mitochondrial	10	99334091	BG165743	112817	10q24.2	Hs.180346	4	mitochondrion metabolic process lyase activity
231871_at	0.578	4.686	5.327	8.069e-05	0.049	1.681	GPR180	G protein-coupled receptor 180	13	94052104	AU160685	160897	13q32.1	Hs.657472	7	membrane integral to membrane
59625_at	-0.422	7.889	-5.322	8.141e-05	0.049	1.673	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	16	65765370	AI912351	8996	16q21-q23	Hs.513667	22	RNA binding intracellular nucleus nucleolus cytoplasm cytosol mRNA processing anti-apoptosis RNA splicing identical protein binding regulation of apoptosis
222858_s_at	0.573	5.408	5.315	8.264e-05	0.049	1.660	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	AI632216	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
200994_at	-0.428	10.164	-5.305	8.418e-05	0.049	1.643	IPO7	importin 7	11	9362744	BG291787	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
1553971_a_at	-1.302	6.969	-5.295	8.573e-05	0.050	1.627	GATS	GATS, stromal antigen 3 opposite strand	7	-99644496, -99636215	AL831967	352954	7q22.1	Hs.556063 Hs.718406	4
218312_s_at	0.819	7.394	5.289	8.685e-05	0.050	1.616	ZSCAN18	zinc finger and SCAN domain containing 18	19	-63310783, -63287021, -63287021	NM_023926	65982	19q13.43	Hs.235390	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212886_at	-0.645	9.167	-5.276	8.898e-05	0.050	1.595	CCDC69	coiled-coil domain containing 69	5	-150540805	AL080169	26112	5q33.1	Hs.655336	3
242056_at	0.636	7.261	5.276	8.901e-05	0.050	1.594	TRIM45	tripartite motif-containing 45	1	-117455199	AI793200	80263	1p13.1	Hs.301526	8	protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding
228450_at	0.703	3.691	5.275	8.921e-05	0.050	1.592	PLEKHA7	pleckstrin homology domain containing, family A member 7	11	-16765787	AA758861	144100	11p15.1	Hs.12332	4	protein binding
221432_s_at	0.586	7.402	5.268	9.032e-05	0.050	1.581	SLC25A28	solute carrier family 25, member 28	10	-101360264	NM_031212	81894	10q23-q24	Hs.403790	6	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
218211_s_at	0.759	7.239	5.262	9.141e-05	0.050	1.571	MLPH	melanophilin	2	238060616	NM_024101	79083	2q37.3	Hs.102406	23	protein binding cytoplasm intracellular protein transport zinc ion binding Rab GTPase binding metal ion binding
217609_at	0.562	4.405	5.251	9.341e-05	0.050	1.552	LRRC23	leucine rich repeat containing 23	12	6884157	BG420747	10233	12p13	Hs.155586	10	molecular_function protein binding cellular_component biological_process
200758_s_at	-0.631	11.205	-5.235	9.623e-05	0.050	1.526	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	AI361227	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
237560_at	0.716	5.661	5.220	9.917e-05	0.051	1.499	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	AI015881	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
242323_at	0.688	8.505	5.208	1.015e-04	0.051	1.479	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AV714268	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
220340_at	1.262	6.134	5.207	1.016e-04	0.051	1.478	KIAA1772	KIAA1772	18	17076200	NM_024935	80000	18q11.1-q11.2	Hs.149020	4	membrane integral to membrane
203466_at	0.485	6.450	5.186	1.059e-04	0.053	1.441	MPV17	MpV17 mitochondrial inner membrane protein	2	-27385863	NM_002437	4358	2p23.3	Hs.75659	17	mitochondrial genome maintenance molecular_function mitochondrion mitochondrial inner membrane integral to peroxisomal membrane oxygen and reactive oxygen species metabolic process membrane integral to membrane homeostatic process
231358_at	0.580	5.244	5.171	1.089e-04	0.054	1.416	MRO	maestro	18	-46575487, -46575487	BE465760	83876	18q21	Hs.30495	6	binding nucleus nucleolus
204671_s_at	0.738	5.498	5.139	1.158e-04	0.057	1.362	ANKRD6	ankyrin repeat domain 6	6	90199615	BE677131	22881	6q14.2-q16.1	Hs.702213	9	protein binding
1554485_s_at	0.736	3.900	5.121	1.199e-04	0.058	1.331	TMEM37	transmembrane protein 37	2	119905915	BI825302	140738	2q14.2	Hs.26216	3	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane
1556051_a_at	0.825	4.579	5.111	1.223e-04	0.058	1.314	BICD1	bicaudal D homolog 1 (Drosophila)	12	32151451	CA777994	636	12p11.2-p11.1	Hs.505202	17	structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis
201906_s_at	1.109	7.024	5.110	1.226e-04	0.058	1.312	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	NM_005808	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
224819_at	0.644	6.667	5.108	1.230e-04	0.058	1.309	TCEAL8	transcription elongation factor A (SII)-like 8	X	-102394578	AI743979	90843	Xq22.1	Hs.389734	4	nucleus regulation of transcription
211654_x_at	0.610	6.355	5.099	1.252e-04	0.058	1.293	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M17565	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
209605_at	0.880	8.090	5.097	1.256e-04	0.058	1.290	TST	thiosulfate sulfurtransferase (rhodanese)	22	-35736851	D87292	7263	22q13.1	Hs.474783	25	thiosulfate sulfurtransferase activity mitochondrion mitochondrial matrix plasma membrane sulfate transport cyanate catabolic process transferase activity
209439_s_at	0.580	6.957	5.093	1.268e-04	0.058	1.282	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	D38616	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
234000_s_at	0.571	6.614	5.073	1.318e-04	0.058	1.248	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	15	63609879	AJ271091	51495	15q22.2	Hs.512973	13	molecular_function GTPase activator activity protein binding cellular_component I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity small GTPase mediated signal transduction Rho protein signal transduction membrane integral to membrane Rac protein signal transduction
1555363_s_at	0.402	5.734	5.056	1.361e-04	0.059	1.219	LOC284440	hypothetical LOC284440	19	-19728182	BC034236	284440	19p13.11	Hs.665307	4
218611_at	-1.447	7.569	-5.040	1.406e-04	0.060	1.191	IER5	immediate early response 5	1	179324260	NM_016545	51278	1q25.3	Hs.716489	8
224558_s_at	-0.940	9.293	-5.031	1.430e-04	0.060	1.176	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AI446756	378938	11q13.1	Hs.642877 Hs.714394	8
206847_s_at	0.922	7.004	5.027	1.441e-04	0.060	1.169	HOXA7	homeobox A7	7	-27159862	AF026397	3204	7p15-p14	Hs.660918	24	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding negative regulation of keratinocyte differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
227337_at	-1.145	7.241	-5.023	1.453e-04	0.060	1.161	ANKRD37	ankyrin repeat domain 37	4	186554833	AA886870	353322	4q35.1	Hs.508154	4	nucleus cytoplasm
218639_s_at	0.529	6.765	5.008	1.495e-04	0.060	1.136	ZXDC	ZXD family zinc finger C	3	-127652648, -127639133	NM_025112	79364	3q21.3	Hs.440049 Hs.711046	8	nucleic acid binding transcription factor activity intracellular nucleus zinc ion binding transcription activator activity LRR domain binding identical protein binding positive regulation of transcription metal ion binding C2H2 zinc finger domain binding
205951_at	-2.775	11.141	-5.005	1.503e-04	0.060	1.131	MYH1	myosin, heavy chain 1, skeletal muscle, adult	17	-10336348	NM_005963	4619	17p13.1	Hs.689619	30	nucleotide binding motor activity actin binding calmodulin binding ATP binding nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction myosin complex myofibril A band	Tight junction
219604_s_at	0.404	4.535	5.004	1.508e-04	0.060	1.128	ZNF3	zinc finger protein 3	7	-99505529, -99499588	NM_017715	7551	7q22.1	Hs.435302	10	transcription factor activity intracellular nucleus nucleus nucleolus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding cell differentiation identical protein binding leukocyte activation metal ion binding
217555_at	-0.517	5.076	-5.000	1.518e-04	0.060	1.123	SMC1A	structural maintenance of chromosomes 1A	X	-53417794	AI042030	8243	Xp11.22-p11.21	Hs.211602	47	cell cycle checkpoint nucleotide binding nuclear mRNA splicing, via spliceosome condensed chromosome kinetochore condensed nuclear chromosome chromatin binding microtubule motor activity protein binding ATP binding nucleus chromosome cytoplasm DNA repair response to DNA damage stimulus cell cycle mitotic spindle organization mitotic sister chromatid cohesion meiosis cohesin core heterodimer response to radiation DNA damage response, signal transduction protein heterodimerization activity chromosome organization cell division	Cell cycle
210210_at	0.396	6.120	4.997	1.528e-04	0.060	1.117	MPZL1	myelin protein zero-like 1	1	165957810	AF181660	9019	1q24.2	Hs.493919 Hs.603116	19	structural molecule activity protein binding integral to plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling membrane	Cell adhesion molecules (CAMs)
216197_at	0.504	4.660	4.980	1.580e-04	0.061	1.087	ATF7IP	activating transcription factor 7 interacting protein	12	14409877	AK021569	55729	12p13.1	Hs.714407	17	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding nucleus transcription factor complex cytoplasm DNA methylation ATPase activity interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent regulation of transcriptional preinitiation complex assembly
222380_s_at	0.582	6.494	4.973	1.601e-04	0.061	1.075	PDCD6	programmed cell death 6	5	324735	AI907083	10016	5p15.33	Hs.50823	36	calcium ion binding nucleus endoplasmic reticulum apoptosis induction of apoptosis by extracellular signals membrane calcium-dependent protein binding response to calcium ion
226452_at	0.487	6.503	4.956	1.656e-04	0.063	1.045	PDK1	pyruvate dehydrogenase kinase, isozyme 1	2	173129024	AU146532	5163	2q31.1	Hs.470633	52	two-component sensor activity nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrial matrix carbohydrate metabolic process glucose metabolic process signal transduction small GTPase mediated signal transduction transferase activity peptidyl-histidine phosphorylation	T cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway
1558487_a_at	0.625	7.829	4.949	1.677e-04	0.063	1.034	TMED4	transmembrane emp24 protein transport domain containing 4	7	-44585286	AK074557	222068	7p13	Hs.598832 Hs.715273	11	endoplasmic reticulum transport membrane integral to membrane
228920_at	0.563	5.963	4.941	1.704e-04	0.063	1.020	ZNF260	zinc finger protein 260	19	-41693433	BE328273	339324	19q13.12	Hs.18103	5	DNA binding intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
220703_at	1.484	7.471	4.940	1.709e-04	0.063	1.018	C10orf110	chromosome 10 open reading frame 110	10	1058576	NM_018470	55853	10p15.3	Hs.644603	2
1555793_a_at	0.748	4.722	4.937	1.718e-04	0.063	1.013	ZFP82	zinc finger protein 82 homolog (mouse)	19	-41574700	AL834267	284406	19q13.12	Hs.558734	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
223044_at	0.621	9.868	4.933	1.734e-04	0.064	1.005	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	2	-190133560	AL136944	30061	2q32	Hs.643005	73	iron ion transmembrane transporter activity iron ion binding cytoplasm plasma membrane integral to plasma membrane ion transport iron ion transport cellular iron ion homeostasis synaptic vesicle anatomical structure morphogenesis
229012_at	0.564	5.291	4.911	1.810e-04	0.066	0.966	C9orf24	chromosome 9 open reading frame 24	9	-34369016, -34369016	AW269443	84688	9p13.3	Hs.50334	8
212689_s_at	-0.981	6.775	-4.903	1.838e-04	0.066	0.953	KDM3A	lysine (K)-specific demethylase 3A	2	86521781, 86522094	AA524505	55818	2p11.2	Hs.557425	11	iron ion binding nucleus cytoplasm spermatogenesis zinc ion binding hormone-mediated signaling oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cell differentiation androgen receptor signaling pathway histone H3-K9 demethylation positive regulation of transcription formaldehyde biosynthetic process metal ion binding androgen receptor binding oxidation reduction
1553102_a_at	-0.742	8.649	-4.890	1.885e-04	0.067	0.931	CCDC69	coiled-coil domain containing 69	5	-150540805	BC016647	26112	5q33.1	Hs.655336	3
218959_at	-0.605	7.426	-4.883	1.909e-04	0.067	0.919	HOXC10	homeobox C10	12	52665212	NM_017409	3226	12q13.3	Hs.44276	13	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation proximal/distal pattern formation cyclin-dependent protein kinase activating kinase holoenzyme complex spinal cord motor neuron cell fate specification embryonic limb morphogenesis sequence-specific DNA binding neuromuscular process
206869_at	0.479	5.324	4.882	1.916e-04	0.067	0.916	CHAD	chondroadherin	17	-45896851	NM_001267	1101	17q21.33	Hs.97220	6	regulation of cell growth extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix	Focal adhesion ECM-receptor interaction
219355_at	0.882	5.146	4.880	1.922e-04	0.067	0.913	CXorf57	chromosome X open reading frame 57	X	105741815	NM_018015	55086	Xq22.3	Hs.274267	5
209419_at	0.332	3.388	4.877	1.933e-04	0.067	0.908	THOC5	THO complex 5	22	-28234155, -28234155	AB023200	8563	22q12.2	Hs.75361	18	protein binding nucleus cytoplasm cell differentiation negative regulation of macrophage differentiation
205374_at	-0.463	13.454	-4.872	1.954e-04	0.067	0.898	SLN	sarcolipin	11	-107083310	NM_003063	6588	11q22-q23	Hs.334629	12	membrane integral to membrane sarcoplasmic reticulum enzyme regulator activity regulation of calcium ion transport
225308_s_at	0.658	6.133	4.867	1.974e-04	0.067	0.889	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	2	159533391	AB051515	85461	2q24.2	Hs.61590	6	binding plasma membrane postsynaptic density cell junction synapse postsynaptic membrane
227340_s_at	-1.264	5.307	-4.860	1.999e-04	0.067	0.879	RGMB	RGM domain family, member B	5	98132898	AL117590	285704	5q15	Hs.526902	5	ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane
224467_s_at	0.407	7.400	4.853	2.028e-04	0.068	0.865	PDCD2L	programmed cell death 2-like	19	39587142	BC006146	84306	19q13.11	Hs.515344	5	cytoplasm
213572_s_at	-0.722	6.314	-4.846	2.056e-04	0.068	0.853	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	6	-2778732	AI554300	1992	6p25	Hs.381167	18	serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity
212172_at	0.552	5.354	4.844	2.064e-04	0.068	0.850	AK2	adenylate kinase 2	1	-33251169, -33246172	AW277253	204	1p34	Hs.470907	16	nucleotide binding adenylate kinase activity ATP binding mitochondrion mitochondrial intermembrane space mitochondrial intermembrane space nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity nucleoside kinase activity	Purine metabolism Metabolic pathways
49329_at	0.359	6.655	4.843	2.069e-04	0.068	0.848	KLHL22	kelch-like 22 (Drosophila)	22	-19125805	N38751	84861	22q11.21	Hs.517419	6	protein binding
220235_s_at	-0.987	6.973	-4.834	2.107e-04	0.068	0.832	C1orf103	chromosome 1 open reading frame 103	1	-111291334	NM_018372	55791	1p13.3	Hs.25245	7	protein binding
202641_at	0.544	6.960	4.832	2.115e-04	0.068	0.828	ARL3	ADP-ribosylation factor-like 3	10	-104423477	NM_004311	403	10q23.3	Hs.182215	18	nucleotide binding magnesium ion binding GTP binding intracellular nucleus Golgi apparatus spindle cell cycle small GTPase mediated signal transduction membrane cell division
201538_s_at	-0.713	7.274	-4.828	2.130e-04	0.069	0.822	DUSP3	dual specificity phosphatase 3	17	-39199014	NM_004090	1845	17q21	Hs.181046	21	protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleoplasm protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity	MAPK signaling pathway
203208_s_at	-0.446	7.452	-4.823	2.150e-04	0.069	0.813	MTFR1	mitochondrial fission regulator 1	8	66719441, 66719441, 66744661	NM_014637	9650	8q13.1	Hs.584788	8	mitochondrion plasma membrane
241458_at	-0.436	4.612	-4.814	2.188e-04	0.069	0.798	SETD2	SET domain containing 2	3	-47032903	AI868267	29072	3p21.31	Hs.517941	18	DNA binding protein binding nucleus methyltransferase activity oxidoreductase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription transition metal ion binding	Lysine degradation
210694_s_at	0.677	5.799	4.813	2.195e-04	0.069	0.795	MID1	midline 1 (Opitz/BBB syndrome)	X	-10373595, -10373595, -10373595	AF041209	4281	Xp22	Hs.27695	38	microtubule cytoskeleton organization protein binding intracellular cytoplasm microtubule microtubule associated complex negative regulation of microtubule depolymerization pattern specification process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
221027_s_at	0.786	8.404	4.800	2.251e-04	0.071	0.773	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	NM_030821	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
242915_at	1.139	3.739	4.795	2.274e-04	0.071	0.764	ZNF682	zinc finger protein 682	19	-19976226, -19976226	AA603590	91120	19p12	Hs.306298	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225719_s_at	0.416	7.148	4.783	2.329e-04	0.072	0.742	MRPL55	mitochondrial ribosomal protein L55	1	-226361002	BG497783	128308	1q42.13	Hs.63236	11	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation
200593_s_at	-0.402	7.885	-4.776	2.360e-04	0.072	0.731	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	BC003621	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
228728_at	0.593	9.498	4.759	2.439e-04	0.074	0.701	C7orf58	chromosome 7 open reading frame 58	7	120415986, 120416680	BF724137	79974	7q31.31	Hs.189652	13	endoplasmic reticulum
226822_at	0.646	5.658	4.759	2.440e-04	0.074	0.701	STOX2	storkhead box 2	4	185063502	AL512713	56977	4q35.1	Hs.21958 Hs.696657	3
204422_s_at	1.314	3.435	4.759	2.442e-04	0.074	0.700	FGF2	fibroblast growth factor 2 (basic)	4	123967312	NM_002006	2247	4q26-q27	Hs.284244	320	activation of MAPKK activity activation of MAPK activity induction of an organ positive regulation of protein amino acid phosphorylation protein binding extracellular region extracellular region extracellular space apoptosis chemotaxis signal transduction Ras protein signal transduction multicellular organismal development nervous system development growth factor activity heparin binding negative regulation of cell proliferation fibroblast growth factor receptor signaling pathway organ morphogenesis glial cell differentiation positive regulation of granule cell precursor proliferation lung development positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration positive regulation of cell differentiation positive regulation of angiogenesis regulation of retinal cell programmed cell death positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
228093_at	0.448	5.602	4.753	2.471e-04	0.074	0.690	ZNF599	zinc finger protein 599	19	-39940818	AW300140	148103	19q13.11	Hs.590961	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226764_at	0.497	5.671	4.747	2.502e-04	0.075	0.678	ZNF827	zinc finger protein 827	4	-146901337	BG542955	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225564_at	0.626	5.002	4.712	2.678e-04	0.079	0.618	SPATA13	spermatogenesis associated 13	13	23632886	AW269397	221178	13q12.12	Hs.657121	7	Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
221838_at	0.411	4.960	4.698	2.757e-04	0.080	0.592	KLHL22	kelch-like 22 (Drosophila)	22	-19125805	N38751	84861	22q11.21	Hs.517419	6	protein binding
204784_s_at	-1.650	8.892	-4.691	2.796e-04	0.081	0.580	MLF1	myeloid leukemia factor 1	3	159771646	NM_022443	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
223373_s_at	0.650	8.632	4.680	2.858e-04	0.082	0.560	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AF306567	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
212817_at	-0.663	7.814	-4.677	2.873e-04	0.082	0.555	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	9	34979724, 34980266	AK023253	25822	9p13.3	Hs.237506	5	protein folding response to unfolded protein heat shock protein binding unfolded protein binding
227074_at	0.611	6.817	4.671	2.906e-04	0.082	0.545	LOC100131564	hypothetical protein LOC100131564	1		AA524669	100131564	1p22.1	Hs.648647
212928_at	0.462	6.685	4.664	2.949e-04	0.082	0.532	TSPYL4	TSPY-like 4	6	-116677823	AL050331	23270	6q22.1	Hs.284141	7	nucleus nucleosome assembly
1558251_a_at	0.456	3.079	4.662	2.962e-04	0.082	0.528	ZNF587	zinc finger protein 587	19	63053080	AK055448	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204608_at	0.673	5.290	4.660	2.971e-04	0.082	0.525	ASL	argininosuccinate lyase	7	65178210, 65178268	NM_000048	435	7cen-q11.2	Hs.632015	19	urea cycle argininosuccinate metabolic process response to hypoxia kidney development liver development argininosuccinate lyase activity cytoplasm arginine catabolic process response to nutrient locomotory behavior cellular amino acid biosynthetic process post-embryonic development lyase activity ammonia assimilation cycle arginine biosynthetic process via ornithine response to peptide hormone stimulus response to steroid hormone stimulus response to glucocorticoid stimulus response to cAMP	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Metabolic pathways
202669_s_at	0.495	5.383	4.646	3.060e-04	0.084	0.499	EFNB2	ephrin-B2	13	-105940096	U16797	1948	13q33	Hs.149239	71	lymph vessel development plasma membrane integral to plasma membrane cell-cell signaling multicellular organismal development nervous system development organ morphogenesis cell differentiation interspecies interaction between organisms ephrin receptor binding	Axon guidance
243612_at	0.562	4.969	4.644	3.068e-04	0.084	0.497	NSD1	nuclear receptor binding SET domain protein 1	5	176492685, 176493438	AL526448	64324	5q35.2-q35.3	Hs.106861	36	negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription corepressor activity protein binding nucleus methyltransferase activity zinc ion binding chromatin modification histone methylation transferase activity ligand-dependent nuclear receptor binding estrogen receptor binding histone methyltransferase activity (H4-K20 specific) regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	Lysine degradation
203773_x_at	0.466	8.645	4.623	3.202e-04	0.087	0.458	BLVRA	biliverdin reductase A	7	43764796	NM_000712	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
232184_at	-0.406	2.824	-4.621	3.212e-04	0.087	0.456	ALS2	amyotrophic lateral sclerosis 2 (juvenile)	2	-202332427, -202273231	AK023024	57679	2q33.1	Hs.471096 Hs.621812	36	ruffle guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity protein binding intracellular early endosome centrosome cytosol endosome organization cell death Rab guanyl-nucleotide exchange factor activity Rab GTPase binding Rab GTPase binding lamellipodium dendrite Rac guanyl-nucleotide exchange factor activity positive regulation of Rac GTPase activity positive regulation of Rac protein signal transduction regulation of Rho protein signal transduction vesicular fraction protein homodimerization activity protein complex protein serine/threonine kinase activator activity positive regulation of protein kinase activity neuron projection morphogenesis regulation of endosome size	Amyotrophic lateral sclerosis (ALS)
91682_at	0.439	5.283	4.605	3.314e-04	0.090	0.428	EXOSC4	exosome component 4	8	145205509	AI571298	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
217993_s_at	-0.583	9.801	-4.593	3.397e-04	0.090	0.406	MAT2B	methionine adenosyltransferase II, beta	5	162862808, 162865162	NM_013283	27430	5q34-q35	Hs.54642	20	catalytic activity protein binding intracellular nucleus S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process metabolic process dTDP-4-dehydrorhamnose reductase activity extracellular polysaccharide biosynthetic process methionine adenosyltransferase complex methionine adenosyltransferase regulator activity methionine adenosyltransferase regulator activity	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
200655_s_at	-0.487	10.516	-4.589	3.425e-04	0.090	0.398	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	NM_006888	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
238681_at	0.687	4.511	4.589	3.426e-04	0.090	0.398	GDPD1	glycerophosphodiester phosphodiesterase domain containing 1	17	54652615	R46180	284161	17q22	Hs.631744	6	glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity
235753_at	0.724	7.886	4.588	3.433e-04	0.090	0.396	HOXA7	homeobox A7	7	-27159862	AI492051	3204	7p15-p14	Hs.660918	24	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding negative regulation of keratinocyte differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
239203_at	-1.309	8.595	-4.586	3.447e-04	0.090	0.393	C7orf53	chromosome 7 open reading frame 53	7	111908143, 111908301	AW014728	286006	7q31.1	Hs.396189	5	membrane integral to membrane
244552_at	0.344	3.580	4.584	3.458e-04	0.090	0.390	ZNF788	zinc finger family member 788	19	12064077	AI190287	388507	19p13.2	Hs.127473		DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
205437_at	0.715	5.822	4.573	3.540e-04	0.092	0.369	ZNF211	zinc finger protein 211	19	62836346	NM_006385	10520	19q13.4	Hs.590977	4	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200915_x_at	-0.523	11.862	-4.570	3.559e-04	0.092	0.364	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	NM_004986	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
241602_at	0.343	6.195	4.569	3.566e-04	0.092	0.362	ZNF582	zinc finger protein 582	19	-61586459	BG432829	147948	19q13.43	Hs.244391	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212762_s_at	0.588	4.482	4.561	3.620e-04	0.092	0.349	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10	114699998	AI375916	6934	10q25.3	Hs.593995	246	blood vessel development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter anti-apoptosis cell cycle arrest beta-catenin binding transcription factor binding cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process specific transcriptional repressor activity protein kinase binding pancreas development positive regulation of insulin secretion regulation of hormone metabolic process glucose homeostasis fat cell differentiation regulation of transcription myoblast cell fate commitment Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
200995_at	-0.747	8.955	-4.536	3.806e-04	0.095	0.304	IPO7	importin 7	11	9362744	AI741392	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
242660_at	0.863	3.258	4.536	3.809e-04	0.095	0.303	C10orf112	chromosome 10 open reading frame 112	10		AA846789	340895	10p12.31	Hs.662505	4	membrane integral to membrane
235532_at	0.442	3.365	4.535	3.814e-04	0.095	0.302	PIGM	phosphatidylinositol glycan anchor biosynthesis, class M	1	-158264085	AI631888	93183	1q23.2	Hs.552810	7	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring hexosyl groups	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
230055_at	0.492	5.283	4.531	3.850e-04	0.095	0.294	KHDC1	KH homology domain containing 1	6	-74007758	AL037414	80759	6q13	Hs.715645	4	RNA binding membrane integral to membrane
201996_s_at	0.699	5.720	4.523	3.909e-04	0.096	0.280	SPEN	spen homolog, transcriptional regulator (Drosophila)	1	16046945	AL524033	23013	1p36.33-p36.11	Hs.558463	21	nucleotide binding single-stranded DNA binding transcription factor activity transcription corepressor activity RNA binding protein binding nucleus nucleolus regulation of transcription from RNA polymerase II promoter Notch signaling pathway transcription activator activity interspecies interaction between organisms negative regulation of transcription, DNA-dependent
219981_x_at	0.425	7.115	4.522	3.918e-04	0.096	0.278	ZNF587	zinc finger protein 587	19	63053080	NM_017961	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201132_at	-0.576	8.987	-4.521	3.928e-04	0.096	0.276	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	X	100549846	NM_019597	3188	Xq22	Hs.632828	17	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm cytoskeleton heterogeneous nuclear ribonucleoprotein complex
221872_at	0.749	3.695	4.514	3.980e-04	0.097	0.264	RARRES1	retinoic acid receptor responder (tazarotene induced) 1	3	-159905133, -159897590	AI669229	5918	3q25.32	Hs.131269	11	negative regulation of cell proliferation membrane integral to membrane
231569_at	0.420	3.402	4.493	4.149e-04	0.100	0.227	TMEM31	transmembrane protein 31	X	102852492	N58489	203562	Xq22.2	Hs.98843	1	membrane integral to membrane
213473_at	-0.458	6.935	-4.477	4.290e-04	0.101	0.197	BRAP	BRCA1 associated protein	12	-110564332	AL042733	8315	12q24	Hs.530940	12	ubiquitin-protein ligase activity cytoplasm zinc ion binding negative regulation of signal transduction ligase activity modification-dependent protein catabolic process identical protein binding metal ion binding
225876_at	0.713	5.801	4.476	4.293e-04	0.101	0.196	NIPAL3	NIPA-like domain containing 3	1	24614831	T84558	57185	1p36.12-p35.1	Hs.523442	6	membrane integral to membrane
226398_s_at	0.450	7.559	4.476	4.293e-04	0.101	0.196	C10orf4	chromosome 10 open reading frame 4	10	-95418318	AI804930	118924	10q23.33	Hs.658192	7	protein binding nucleus
202203_s_at	-0.877	7.181	-4.473	4.322e-04	0.101	0.190	AMFR	autocrine motility factor receptor	16	-54952864	NM_001144	267	16q21	Hs.295137	33	protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization
220565_at	0.754	4.568	4.471	4.339e-04	0.101	0.187	CCR10	chemokine (C-C motif) receptor 10	17	-38084945	NM_016602	2826	17q21.1-q21.3	Hs.719562	20	receptor activity G-protein coupled receptor activity protein binding plasma membrane integral to plasma membrane chemotaxis signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration C-C chemokine receptor activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
235595_at	0.456	6.625	4.471	4.341e-04	0.101	0.186	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	1	-154183253, -154183253	AW299534	9181	1q21-q22	Hs.655209	28	cell morphogenesis guanyl-nucleotide exchange factor activity intracellular cytoplasm Golgi apparatus spindle microtubule tight junction intracellular protein transport actin filament organization negative regulation of microtubule depolymerization cell cycle mitosis intracellular signaling cascade microtubule binding zinc ion binding diacylglycerol binding cell junction Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction regulation of cell proliferation metal ion binding Rac GTPase binding cell division	Pathogenic Escherichia coli infection - EHEC
1556203_a_at	0.427	3.932	4.457	4.464e-04	0.103	0.161	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	1	204582822, 204582822	AI263819	23380	1q32.1	Hs.497575	7	GTPase activator activity intracellular signal transduction	Axon guidance
213279_at	0.559	5.807	4.446	4.569e-04	0.104	0.141	DHRS1	dehydrogenase/reductase (SDR family) member 1	14	-23829645, -23829645	AL050217	115817	14q12	Hs.719146	13	binding nucleus cytoplasm mitochondrial inner membrane endoplasmic reticulum Golgi apparatus oxidoreductase activity oxidation reduction
219233_s_at	0.334	5.366	4.444	4.581e-04	0.104	0.138	GSDMB	gasdermin B	17	-35314373, -35314373	NM_018530	55876	17q12	Hs.306777	12	cytoplasm
217878_s_at	-0.901	7.117	-4.441	4.615e-04	0.104	0.132	CDC27	cell division cycle 27 homolog (S. cerevisiae)	17	-42550309	AI203880	996	17q12-q23.2	Hs.463295	53	protein binding nucleus nucleoplasm cytoplasm centrosome cytosol spindle microtubule mitotic metaphase/anaphase transition cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
220164_s_at	0.790	8.534	4.439	4.631e-04	0.104	0.129	FBXO40	F-box protein 40	3	122794859	NM_016298	51725	3q13.33	Hs.272564	7	molecular_function cellular_component biological_process zinc ion binding modification-dependent protein catabolic process metal ion binding
217977_at	0.854	9.379	4.437	4.647e-04	0.104	0.125	SEPX1	selenoprotein X, 1	16	-1928234	NM_016332	51734	16p13.3	Hs.655346	11	protein-methionine-R-oxide reductase activity cellular_component nucleus cytoplasm peptide-methionine-(S)-S-oxide reductase activity zinc ion binding selenium binding oxidoreductase activity protein repair metal ion binding oxidation reduction
39549_at	0.622	4.601	4.437	4.647e-04	0.104	0.125	NPAS2	neuronal PAS domain protein 2	2	100803044	AI743090	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
208937_s_at	-1.088	8.418	-4.434	4.681e-04	0.104	0.119	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	20	29656752	D13889	3397	20q11	Hs.504609	112	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleus transforming growth factor beta receptor signaling pathway multicellular organismal development heart development negative regulation of transcription by transcription factor localization negative regulation of transcription transcription repressor activity BMP signaling pathway negative regulation of transcription factor activity blood vessel endothelial cell migration regulation of angiogenesis	TGF-beta signaling pathway
219165_at	1.062	8.954	4.433	4.687e-04	0.104	0.118	PDLIM2	PDZ and LIM domain 2 (mystique)	8	22492587, 22493928, 22493928	NM_021630	64236	8p21.2	Hs.632034	10	protein binding nucleus cytoplasm cytoskeleton zinc ion binding cell surface metal ion binding
1552734_at	-0.356	3.951	-4.432	4.691e-04	0.104	0.117	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	NM_152756	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
226679_at	0.559	6.465	4.432	4.694e-04	0.104	0.116	SLC26A11	solute carrier family 26, member 11	17	75808831	BE964598	284129	17q25.3	Hs.4866	4	transporter activity endoplasmic reticulum Golgi apparatus plasma membrane ion transport secondary active sulfate transmembrane transporter activity sulfate transport anion transmembrane transporter activity anion exchanger activity integral to membrane
227865_at	0.515	5.673	4.429	4.724e-04	0.104	0.111	C9orf103	chromosome 9 open reading frame 103	9	85427785	BF111242	414328	9q21-q22	Hs.530261	1	nucleotide binding molecular_function shikimate kinase activity ATP binding cellular_component carbohydrate metabolic process biological_process transferase activity gluconokinase activity
224435_at	0.667	8.214	4.425	4.767e-04	0.104	0.103	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	BC005871	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
218164_at	0.609	7.072	4.422	4.788e-04	0.104	0.099	SPATA20	spermatogenesis associated 20	17	45979560	NM_022827	64847	17q21.33	Hs.103147	7	catalytic activity protein binding multicellular organismal development spermatogenesis cell differentiation
241459_at	0.788	7.082	4.422	4.790e-04	0.104	0.098	LIMCH1	LIM and calponin homology domains 1	4	41057560, 41309675	AI494113	22998	4p13	Hs.335163	10	actin binding zinc ion binding actomyosin structure organization metal ion binding
200759_x_at	-0.539	11.280	-4.417	4.836e-04	0.104	0.090	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	NM_003204	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
211729_x_at	0.435	8.716	4.416	4.850e-04	0.104	0.087	BLVRA	biliverdin reductase A	7	43764796	BC005902	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
232599_at	1.092	4.447	4.410	4.907e-04	0.104	0.077	EXOC6	exocyst complex component 6	10	94584449, 94598204	AF220217	54536	10q23.33	Hs.655657	8	exocyst vesicle docking during exocytosis protein transport
206891_at	-2.645	9.865	-4.410	4.911e-04	0.104	0.076	ACTN3	actinin, alpha 3	11	66070966	NM_001104	89	11q13.1	Hs.654432	47	actin binding integrin binding calcium ion binding protein binding actin filament focal adhesion structural constituent of muscle pseudopodium protein homodimerization activity regulation of apoptosis focal adhesion formation	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
236574_at	0.340	5.748	4.401	5.001e-04	0.105	0.060	LOC284373	hypothetical protein LOC284373	19		AI304870	284373	19q13.41	Hs.188680	1
36829_at	-0.802	7.455	-4.401	5.002e-04	0.105	0.060	PER1	period homolog 1 (Drosophila)	17	-7984512	AF022991	5187	17p13.1-p12	Hs.445534	54	signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm entrainment of circadian clock negative regulation of transcription	Circadian rhythm - mammal
224752_at	-0.335	9.383	-4.399	5.015e-04	0.105	0.057	PL-5283	PL-5283 protein	7	134997760	BG031051	647087	7q33	Hs.200022	3
235291_s_at	0.518	4.037	4.394	5.071e-04	0.106	0.047	FLJ32255	hypothetical protein LOC643977	5		BE875232	643977	5p12	Hs.535791	1
224476_s_at	0.530	7.217	4.389	5.118e-04	0.106	0.039	MESP1	mesoderm posterior 1 homolog (mouse)	15	-88094103	BC006219	55897	15q26.1	Hs.447531	4	heart morphogenesis DNA binding nucleus Notch signaling pathway multicellular organismal development mesodermal cell migration transcription regulator activity regulation of transcription
232024_at	1.092	5.023	4.389	5.121e-04	0.106	0.038	GIMAP2	GTPase, IMAP family member 2	7	150013726	AI431931	26157	7q36.1	Hs.647071	5	nucleotide binding GTP binding membrane integral to membrane
217741_s_at	-1.023	8.246	-4.383	5.178e-04	0.107	0.028	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AW471220	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
210652_s_at	0.870	4.608	4.376	5.255e-04	0.108	0.015	TTC39A	tetratricopeptide repeat domain 39A	1	-51525518, -51525518	BC004399	22996	1p32.3	Hs.112949	3	binding cellular_component biological_process
203207_s_at	-0.662	5.109	-4.345	5.593e-04	0.113	-0.041	MTFR1	mitochondrial fission regulator 1	8	66719441, 66719441, 66744661	BF214329	9650	8q13.1	Hs.584788	8	mitochondrion plasma membrane
227054_at	0.391	7.055	4.344	5.611e-04	0.113	-0.043	N6AMT2	N-6 adenine-specific DNA methyltransferase 2 (putative)	13	-20201072	AI141584	221143	13q12.11	Hs.26674	3	nucleic acid binding methyltransferase activity transferase activity methylation
207076_s_at	1.411	7.831	4.343	5.617e-04	0.113	-0.044	ASS1	argininosuccinate synthetase 1	9	132309914	NM_000050	445	9q34.1	Hs.160786	40	urea cycle nucleotide binding argininosuccinate synthase activity protein binding ATP binding cytoplasm arginine biosynthetic process cellular amino acid biosynthetic process ligase activity	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Metabolic pathways
217975_at	0.623	7.011	4.339	5.662e-04	0.113	-0.052	WBP5	WW domain binding protein 5	X	102498035	NM_016303	51186	Xq22.2	Hs.533287	6	protein binding WW domain binding
1568900_a_at	0.458	3.053	4.337	5.684e-04	0.113	-0.055	ZNF568	zinc finger protein 568	19	42099073	BC031218	374900	19q13.12	Hs.404220	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203235_at	0.338	6.272	4.336	5.696e-04	0.113	-0.057	THOP1	thimet oligopeptidase 1	19	2736505	NM_003249	7064	19q13.3	Hs.78769	24	metalloendopeptidase activity protein binding cytoplasm proteolysis peptide metabolic process protein kinase cascade peptidase activity zinc ion binding metal ion binding	Renin-angiotensin system
209829_at	1.232	7.000	4.333	5.733e-04	0.114	-0.063	FAM65B	family with sequence similarity 65, member B	6	-24947573, -24912491	AB002384	9750	6p22.3-p21.32	Hs.559459	7	binding cytoplasm mitochondrion cytoskeleton multicellular organismal development muscle organ development cell differentiation filopodium
217655_at	0.381	3.262	4.330	5.765e-04	0.114	-0.068	LOC100127972	hypothetical LOC100127972	19		BE552409	100127972	19q13.12	Hs.710764 Hs.716895	1
215286_s_at	-0.486	4.704	-4.327	5.803e-04	0.114	-0.074	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AL050389	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
210445_at	0.373	4.524	4.312	5.986e-04	0.116	-0.102	FABP6	fatty acid binding protein 6, ileal	5	159546951, 159558625, 159589014	U19869	2172	5q33.3-q34	Hs.519719	18	transporter activity fatty acid binding cytoplasm cytosol lipid metabolic process transport steroid metabolic process negative regulation of cell proliferation	PPAR signaling pathway
236972_at	-1.271	10.165	-4.306	6.053e-04	0.116	-0.112	TRIM63	tripartite motif-containing 63	1	-26250384	AI351421	84676	1p34-p33	Hs.279709	20	ubiquitin-protein ligase activity signal transducer activity protein binding intracellular nucleus cytoplasm cytoplasm microtubule muscle contraction signal transduction zinc ion binding ligase activity modification-dependent protein catabolic process titin binding proteasomal ubiquitin-dependent protein catabolic process contractile fiber metal ion binding
202808_at	-0.621	7.423	-4.306	6.054e-04	0.116	-0.112	C10orf26	chromosome 10 open reading frame 26	10	104493716, 104525877	AK000161	54838	10q24.32	Hs.500897 Hs.693257 Hs.707763	9	membrane integral to membrane
205903_s_at	-0.485	4.868	-4.303	6.098e-04	0.116	-0.118	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1	-152946536, -152946536	NM_002249	3782	1q21.3	Hs.490765	40	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
238844_s_at	-0.809	5.808	-4.299	6.142e-04	0.117	-0.125	NPHP1	nephronophthisis 1 (juvenile)	2	-110238202	BF216535	4867	2q13	Hs.280388	36	structural molecule activity protein binding adherens junction signal transduction excretion visual behavior membrane cell-cell adhesion actin cytoskeleton organization cell junction
215175_at	0.530	5.740	4.296	6.185e-04	0.117	-0.131	PCNX	pecanex homolog (Drosophila)	14	70443874	AB023212	22990	14q24.2	Hs.446559	10	membrane integral to membrane
225329_at	0.350	6.748	4.292	6.231e-04	0.117	-0.138	LOC348262	hypothetical protein LOC348262	17	-2338651	BF338291	348262	17q25.3	Hs.514632	1
208754_s_at	-0.694	7.540	-4.285	6.324e-04	0.118	-0.151	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AL162068	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
202891_at	0.437	7.566	4.276	6.434e-04	0.120	-0.166	NIT1	nitrilase 1	1	159354514	NM_005600	4817	1q21-q22	Hs.517342	7	nitrilase activity nitrogen compound metabolic process biological_process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
205898_at	0.940	6.220	4.272	6.491e-04	0.120	-0.174	CX3CR1	chemokine (C-X3-C motif) receptor 1	3	-39279988	U20350	1524	3p21 3p21.3	Hs.78913	123	receptor activity G-protein coupled receptor activity chemokine receptor activity protein binding plasma membrane integral to plasma membrane chemotaxis cellular defense response cell adhesion signal transduction G-protein coupled receptor protein signaling pathway response to wounding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway
203711_s_at	-0.514	7.456	-4.271	6.509e-04	0.120	-0.177	HIBCH	3-hydroxyisobutyryl-Coenzyme A hydrolase	2	-190777604	NM_014362	26275	2q32.2	Hs.656685	8	3-hydroxyisobutyryl-CoA hydrolase activity protein binding mitochondrion metabolic process branched chain family amino acid catabolic process hydrolase activity	Valine, leucine and isoleucine degradation beta-Alanine metabolism Propanoate metabolism Metabolic pathways
238444_at	0.481	4.787	4.270	6.511e-04	0.120	-0.177	ZNF618	zinc finger protein 618	9	115678382	AV704303	114991	9q32	Hs.349208	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity
219926_at	-0.555	10.266	-4.269	6.528e-04	0.120	-0.179	POPDC3	popeye domain containing 3	6	-105712475, -105712475	NM_022361	64208	6q21	Hs.458336	7	molecular_function biological_process membrane integral to membrane
229178_at	0.458	4.428	4.267	6.557e-04	0.120	-0.183	PRTG	protogenin homolog (Gallus gallus)	15	-53691041	AV699825	283659	15q21.3	Hs.130957	4	multicellular organismal development membrane integral to membrane
213229_at	0.614	7.505	4.266	6.570e-04	0.120	-0.185	DICER1	dicer 1, ribonuclease type III	14	-94622317, -94622317	BF590131	23405	14q32.13	Hs.87889	63	nucleotide binding magnesium ion binding angiogenesis double-stranded RNA binding helicase activity endonuclease activity ribonuclease III activity protein binding ATP binding intracellular cytoplasm RNA processing ATP-dependent helicase activity RNA-induced silencing complex hydrolase activity stem cell maintenance manganese ion binding lung development RNA interference, production of siRNA RNA interference, targeting of mRNA for destruction gene silencing by RNA pre-microRNA processing embryonic hindlimb morphogenesis branching morphogenesis of a tube
214643_x_at	-0.538	9.148	-4.259	6.661e-04	0.121	-0.198	BIN1	bridging integrator 1	2	-127522077, -127522076	BG034080	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
227923_at	0.598	7.008	4.258	6.675e-04	0.121	-0.199	SHANK3	SH3 and multiple ankyrin repeat domains 3	22	49459935	BF439330	85358	22q13.3	Hs.149035	21	MAPKKK cascade embryonic epithelial tube formation protein binding cytoplasm plasma membrane postsynaptic density SH3 domain binding cell junction synapse postsynaptic membrane
203068_at	-0.684	7.532	-4.253	6.744e-04	0.121	-0.209	KLHL21	kelch-like 21 (Drosophila)	1	-6573370	NM_014851	9903	1p36.31	Hs.7764	5	protein binding modification-dependent protein catabolic process
203575_at	-0.432	7.110	-4.252	6.758e-04	0.121	-0.210	CSNK2A2	casein kinase 2, alpha prime polypeptide	16	-56749312	NM_001896	1459	16q21	Hs.82201	143	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity protein N-terminus binding regulation of cell cycle	Wnt signaling pathway Adherens junction Tight junction
218176_at	0.365	6.626	4.250	6.792e-04	0.121	-0.215	MAGEF1	melanoma antigen family F, 1	3	-185910848	NM_022149	64110	3q13	Hs.306123	4
1405_i_at	0.629	3.772	4.249	6.795e-04	0.121	-0.215	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	M21121	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
223852_s_at	-0.555	7.293	-4.246	6.846e-04	0.122	-0.222	STK40	serine/threonine kinase 40	1	-36577811	BC005169	83931	1p34.3	Hs.471768	11	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity
230329_s_at	0.650	7.493	4.235	6.992e-04	0.124	-0.241	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	4	-124033248, -124033248	AI580268	11162	4q26	Hs.558459	15	cellular_component growth factor activity biological_process hydrolase activity
219629_at	0.522	5.097	4.233	7.023e-04	0.124	-0.245	FAM118A	family with sequence similarity 118, member A	22	44083744, 44084448	NM_017911	55007	22q13	Hs.265018	6	membrane integral to membrane
226879_at	0.349	6.393	4.231	7.051e-04	0.124	-0.249	HVCN1	hydrogen voltage-gated channel 1	12	-109570873, -109570873	AW406569	84329	12q24.11	Hs.211511 Hs.334637	11	voltage-gated ion channel activity ion transport response to pH response to zinc ion response to zinc ion proton transport membrane integral to membrane voltage-gated proton channel activity voltage-gated proton channel activity
242794_at	0.596	3.715	4.229	7.081e-04	0.124	-0.252	MAML3	mastermind-like 3 (Drosophila)	4	-140856995	AI569476	55534	4q28	Hs.586165	7	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
204447_at	0.431	6.198	4.217	7.250e-04	0.126	-0.274	ProSAPiP1	ProSAPiP1 protein	20	-3091272	NM_014731	9762	20p13	Hs.90232	4	structural molecule activity cytoplasm membrane
209029_at	-0.452	7.786	-4.211	7.351e-04	0.127	-0.286	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	12	6703410, 6703440, 6703505, 6703709	AF193844	50813	12p13.31	Hs.530823	16	nucleus cytoplasm signalosome
1559965_at	-0.597	5.394	-4.202	7.477e-04	0.129	-0.301	LOC100192378	hypothetical LOC100192378	8	-77685669	BC037827	100192378	8q21.11	Hs.648649	2
228608_at	0.664	3.211	4.193	7.617e-04	0.130	-0.318	NALCN	sodium leak channel, non-selective	13	-100504130	N49852	259232	13q32.3	Hs.525146	8	voltage-gated ion channel activity sodium channel activity ion transport sodium ion transport membrane integral to membrane sodium ion binding
213462_at	0.545	5.750	4.190	7.663e-04	0.130	-0.323	NPAS2	neuronal PAS domain protein 2	2	100803044	AW000928	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
210202_s_at	-0.698	10.258	-4.186	7.723e-04	0.130	-0.330	BIN1	bridging integrator 1	2	-127522077, -127522076	U87558	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
207551_s_at	-0.483	7.380	-4.186	7.731e-04	0.130	-0.331	MSL3	male-specific lethal 3 homolog (Drosophila)	X	11686198, 11686198, 11687681	NM_006800	10943	Xp22.3	Hs.655288	6	chromatin chromatin binding transcription factor activity nucleus chromatin assembly or disassembly transcription from RNA polymerase II promoter multicellular organismal development chromatin modification regulation of transcription
224950_at	0.536	5.209	4.183	7.779e-04	0.131	-0.337	PTGFRN	prostaglandin F2 receptor negative regulator	1	117254211	BF476250	5738	1p13.1	Hs.418093	14	protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane
213166_x_at	0.652	8.455	4.179	7.843e-04	0.131	-0.344	FAM128A	family with sequence similarity 128, member A	2	-131958002	BG332462	653784	2q21.1	Hs.655067	2
201381_x_at	-0.335	9.087	-4.179	7.844e-04	0.131	-0.344	CACYBP	calcyclin binding protein	1	173235193, 173235514	AF057356	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
212995_x_at	0.561	8.794	4.178	7.856e-04	0.131	-0.346	FAM128B	family with sequence similarity 128, member B	2	130656172	BG255188	80097	2q21.1	Hs.469925 Hs.516450	2
210691_s_at	-0.468	8.089	-4.178	7.858e-04	0.131	-0.346	CACYBP	calcyclin binding protein	1	173235193, 173235514	AF275803	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
202682_s_at	0.318	7.849	4.176	7.894e-04	0.131	-0.350	USP4	ubiquitin specific peptidase 4 (proto-oncogene)	3	-49289580	NM_003363	7375	3p21.3	Hs.403828 Hs.714416 Hs.77500	17	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding nucleus cytoplasm lysosome ubiquitin-dependent protein catabolic process peptidase activity
218891_at	-0.387	7.142	-4.172	7.946e-04	0.131	-0.356	C10orf76	chromosome 10 open reading frame 76	10	-103595345	NM_024541	79591	10q24.32	Hs.16004	4	membrane integral to membrane
214295_at	0.433	4.094	4.172	7.960e-04	0.131	-0.357	KIAA0485	hypothetical LOC57235			AW129056	57235		Hs.604754	1
204135_at	-0.796	8.536	-4.165	8.075e-04	0.132	-0.370	FILIP1L	filamin A interacting protein 1-like	3	-101049461, -101049461, -101034677	NM_014890	11259	3q12.1	Hs.104672	8	molecular_function nucleus cytoplasm biological_process membrane myosin complex
204655_at	0.600	4.472	4.161	8.127e-04	0.132	-0.376	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	NM_002985	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
219584_at	1.617	5.503	4.161	8.139e-04	0.132	-0.377	PLA1A	phospholipase A1 member A	3	120799411	NM_015900	51365	3q13.13-q13.2	Hs.437451	11	extracellular region phosphatidylserine metabolic process phospholipase A1 activity lipid catabolic process hydrolase activity	Tropane, piperidine and pyridine alkaloid biosynthesis
242979_at	0.951	5.326	4.159	8.167e-04	0.133	-0.381	IRS1	insulin receptor substrate 1	2	-227304276	AI474666	3667	2q36	Hs.471508	290	positive regulation of mesenchymal cell proliferation signal transducer activity transmembrane receptor protein tyrosine kinase docking protein activity protein kinase C binding insulin receptor binding insulin-like growth factor receptor binding protein binding nucleus cytoplasm microsome plasma membrane insulin receptor complex caveola signal transduction positive regulation of glucose metabolic process phosphoinositide 3-kinase cascade positive regulation of cell migration mammary gland development positive regulation of fatty acid beta-oxidation SH2 domain binding glucose homeostasis response to peptide hormone stimulus protein kinase B signaling cascade phosphoinositide 3-kinase binding phosphoinositide 3-kinase binding positive regulation of phosphoinositide 3-kinase activity positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of glucose import negative regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway	Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus
204143_s_at	-1.149	6.074	-4.155	8.229e-04	0.133	-0.387	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	NM_017512	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
202003_s_at	0.700	10.017	4.151	8.301e-04	0.134	-0.395	ACAA2	acetyl-Coenzyme A acyltransferase 2	18	-45563871	NM_006111	10449	18q21.1	Hs.200136	10	acetyl-CoA C-acyltransferase activity mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process cholesterol biosynthetic process metabolic process acyltransferase activity transferase activity	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Metabolic pathways
1569852_at	-1.245	7.982	-4.151	8.303e-04	0.134	-0.395	C7orf53	chromosome 7 open reading frame 53	7	111908143, 111908301	BC031976	286006	7q31.1	Hs.396189	5	membrane integral to membrane
229623_at	0.417	6.597	4.149	8.337e-04	0.134	-0.399	FLJ12993	hypothetical LOC441027	4	-83624627	BF508344	441027	4q21.22	Hs.507676	1
202376_at	1.120	5.401	4.143	8.440e-04	0.134	-0.410	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	14	94148466	NM_001085	12	14q32.1	Hs.534293 Hs.710488	134	DNA binding serine-type endopeptidase inhibitor activity protein binding extracellular region intracellular nucleus acute-phase response inflammatory response regulation of lipid metabolic process peptidase inhibitor activity
224367_at	2.819	6.783	4.141	8.471e-04	0.134	-0.413	BEX2	brain expressed X-linked 2	X	-102450929	AF251053	84707	Xq22	Hs.398989	11	nucleus cytoplasm
200999_s_at	0.647	7.516	4.141	8.475e-04	0.134	-0.414	CKAP4	cytoskeleton-associated protein 4	12	-105155789	NM_006825	10970	12q23.3	Hs.714862 Hs.74368	22	membrane fraction endoplasmic reticulum membrane integral to membrane
207717_s_at	0.981	4.432	4.139	8.505e-04	0.134	-0.417	PKP2	plakophilin 2	12	-32834946	NM_004572	5318	12p11	Hs.164384	29	protein binding nucleus cytoskeleton plasma membrane integral to membrane cell-cell adhesion desmosome	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
206799_at	1.544	5.452	4.138	8.520e-04	0.134	-0.419	SCGB1D2	secretoglobin, family 1D, member 2	11	61766299	NM_006551	10647	11q13	Hs.204096	9	binding extracellular region extracellular space
60471_at	0.431	5.612	4.135	8.572e-04	0.134	-0.424	RIN3	Ras and Rab interactor 3	14	92049877	AA625133	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
239084_at	-0.430	4.907	-4.135	8.584e-04	0.134	-0.425	SNAP29	synaptosomal-associated protein, 29kDa	22	19543291	BE896490	9342	22q11.21	Hs.108002 Hs.701035	19	SNAP receptor activity cytoplasm plasma membrane exocytosis vesicle targeting membrane fusion protein transport synaptosome cell junction synapse	SNARE interactions in vesicular transport
215293_s_at	0.287	6.207	4.130	8.670e-04	0.135	-0.434	PGAP2	post-GPI attachment to proteins 2	11	3775529, 3775624, 3775707, 3775765, 3785815, 3786341	AL049261	27315	11p15.5	Hs.133968	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus GPI anchor biosynthetic process protein transporter activity membrane integral to membrane
205011_at	0.467	6.303	4.128	8.703e-04	0.135	-0.438	VWA5A	von Willebrand factor A domain containing 5A	11	123491320, 123491320	NM_014622	4013	11q23	Hs.152944	5
230435_at	0.584	6.759	4.113	8.967e-04	0.138	-0.465	LOC375190	hypothetical protein LOC375190	2	24199853	BF108666	375190	2p23.3	Hs.710370	4
238792_at	0.466	5.515	4.108	9.054e-04	0.138	-0.473	PCNX	pecanex homolog (Drosophila)	14	70443874	BF209668	22990	14q24.2	Hs.446559	10	membrane integral to membrane
210045_at	-0.529	8.326	-4.108	9.064e-04	0.138	-0.474	IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	15	-88428215	AU151428	3418	15q26.1	Hs.596461	20	magnesium ion binding isocitrate dehydrogenase (NADP+) activity mitochondrion carbohydrate metabolic process glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Glutathione metabolism Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
219161_s_at	0.419	5.826	4.107	9.087e-04	0.138	-0.477	CKLF	chemokine-like factor	16	65143966, 65143972	NM_016951	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
1554678_s_at	-0.436	8.367	-4.105	9.125e-04	0.138	-0.480	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	AB066484	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
231940_at	0.614	6.712	4.103	9.150e-04	0.138	-0.483	ZNF529	zinc finger protein 529	19	-41762996, -41726357, -41726357	AI369933	57711	19q13.13	Hs.708146	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226982_at	-0.759	5.535	-4.102	9.169e-04	0.138	-0.485	ELL2	elongation factor, RNA polymerase II, 2	5	-95246557	AI745624	22936	5q15	Hs.192221 Hs.708710	6	RNA polymerase II transcription factor activity nucleus RNA elongation from RNA polymerase II promoter transcription elongation factor complex RNA polymerase II transcription elongation factor activity regulation of transcription
228099_at	0.586	6.394	4.099	9.231e-04	0.139	-0.491	ZNF550	zinc finger protein 550	19	-62750154	AI805301	162972	19q13.43	Hs.180257	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231956_at	0.647	4.951	4.098	9.246e-04	0.139	-0.492	KIAA1618	KIAA1618	17	75849261	AA976354	57714	17q25.3	Hs.514554	5
1557283_a_at	0.612	3.670	4.098	9.257e-04	0.139	-0.493	ZNF519	zinc finger protein 519	18	-14094723	BC037787	162655	18p11.21	Hs.352635	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210140_at	0.399	5.489	4.093	9.342e-04	0.139	-0.501	CST7	cystatin F (leukocystatin)	20	24877865	AF031824	8530	20p11.21	Hs.143212	17	cysteine-type endopeptidase inhibitor activity extracellular region cytoplasm immune response
206030_at	0.632	8.060	4.092	9.356e-04	0.139	-0.503	ASPA	aspartoacylase (Canavan disease)	17	3324153, 3326045	NM_000049	443	17pter-p13	Hs.171142	27	aminoacylase activity nucleus cytoplasm aspartate catabolic process metabolic process zinc ion binding hydrolase activity, acting on ester bonds aspartoacylase activity metal ion binding	Alanine, aspartate and glutamate metabolism Histidine metabolism
228652_at	0.576	7.520	4.085	9.491e-04	0.140	-0.516	ZNF776	zinc finger protein 776	19	62949975	AI279532	284309	19q13.43	Hs.109540	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
220117_at	-0.351	4.670	-4.084	9.526e-04	0.140	-0.519	ZNF385D	zinc finger protein 385D	3	-21437495	NM_024697	79750	3p24.3	Hs.21026	3	nucleic acid binding intracellular nucleus zinc ion binding metal ion binding
218729_at	0.697	6.757	4.080	9.593e-04	0.141	-0.525	LXN	latexin	3	-159866896	NM_020169	56925	3q25.32	Hs.478067	5	enzyme inhibitor activity protein binding cytoplasm metalloendopeptidase inhibitor activity detection of temperature stimulus involved in sensory perception of pain
224630_at	-0.369	7.942	-4.074	9.717e-04	0.142	-0.537	ERLEC1	endoplasmic reticulum lectin 1	2	53867571	AK001913	27248	2p16.2	Hs.438336 Hs.713845	10	protein binding endoplasmic reticulum endoplasmic reticulum lumen
1565759_at	-0.417	5.615	-4.070	9.793e-04	0.143	-0.544	RPL13	ribosomal protein L13	16	88154590, 88154631	BG396520	6137	16q24.3 17p11.2	Hs.410817	17	RNA binding structural constituent of ribosome protein binding intracellular cytosol translational elongation cytosolic ribosome	Ribosome
209397_at	0.657	8.992	4.067	9.861e-04	0.143	-0.550	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	18	46659432	BC000147	4200	18q21 6p25-p24	Hs.233119	24	malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide
208624_s_at	-0.662	6.994	-4.064	9.905e-04	0.143	-0.554	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	3	185515049, 185515664, 185520956	BE966878	1981	3q27-qter	Hs.433750	91	RNA binding translation initiation factor activity protein binding cytoplasm cytosol regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
204067_at	0.403	7.561	4.061	9.972e-04	0.144	-0.560	SUOX	sulfite oxidase	12	54677309	AA129776	6821	12q13.2	Hs.558403	23	mitochondrion mitochondrial intermembrane space cytosol response to nutrient sulfite oxidase activity electron carrier activity oxidoreductase activity heme binding molybdenum ion binding molybdopterin cofactor binding metal ion binding oxidation reduction	Sulfur metabolism
213394_at	0.467	6.371	4.060	1.000e-03	0.144	-0.563	MAPKBP1	mitogen-activated protein kinase binding protein 1	15	39853923	AI674759	23005	15q15.1	Hs.513661	6
219449_s_at	-1.025	10.923	-4.060	1.000e-03	0.144	-0.563	TMEM70	transmembrane protein 70	8	75050983	NM_017866	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
205934_at	-0.884	6.897	-4.053	1.015e-03	0.145	-0.576	PLCL1	phospholipase C-like 1	2	198377670, 198377777	NM_006226	5334	2q33	Hs.153322 Hs.593586	8	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
220116_at	-0.776	6.122	-4.050	1.021e-03	0.145	-0.581	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	5	113725914, 113797125	NM_021614	3781	5q22.3	Hs.98280	15	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
217028_at	0.564	3.911	4.049	1.022e-03	0.145	-0.582	CXCR4	chemokine (C-X-C motif) receptor 4	2	-136588388, -136588388	AJ224869	7852	2q21	Hs.593413	604	activation of MAPK activity response to hypoxia actin binding G-protein coupled receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane apoptosis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration response to virus coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity initiation of viral infection cell leading edge myosin light chain binding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway Endocytosis Axon guidance Leukocyte transendothelial migration
227321_at	-0.873	7.016	-4.049	1.023e-03	0.145	-0.583	GATS	GATS, stromal antigen 3 opposite strand	7	-99644496, -99636215	D52585	352954	7q22.1	Hs.556063 Hs.718406	4
220380_at	0.293	4.012	4.048	1.024e-03	0.145	-0.584	DNASE2B	deoxyribonuclease II beta	1	84636802, 84646621	NM_021233	58511	1p22.3	Hs.129142	5	endodeoxyribonuclease activity deoxyribonuclease II activity extracellular region cytoplasm lysosome DNA metabolic process hydrolase activity	Lysosome
225806_at	0.659	3.152	4.043	1.034e-03	0.146	-0.593	JUB	jub, ajuba homolog (Xenopus laevis)	14	-22510249, -22510249	AI289311	84962	14q11.2	Hs.655832	16	protein binding nucleus cytoplasm centrosome cytoskeleton plasma membrane focal adhesion cell cycle cell adhesion zinc ion binding lamellipodium lamellipodium assembly cell junction regulation of cell migration wound healing, spreading of epidermal cells regulation of GTPase activity metal ion binding focal adhesion formation
1556554_at	0.389	5.834	4.043	1.034e-03	0.146	-0.593	TRIM50	tripartite motif-containing 50	7	-72364470	AK057366	135892	7q11.23	Hs.647053	4	protein binding intracellular cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
1558700_s_at	0.774	4.153	4.039	1.043e-03	0.147	-0.600	ZNF260	zinc finger protein 260	19	-41693433	BC042676	339324	19q13.12	Hs.18103	5	DNA binding intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
202861_at	-1.089	7.351	-4.025	1.075e-03	0.150	-0.628	PER1	period homolog 1 (Drosophila)	17	-7984512	NM_002616	5187	17p13.1-p12	Hs.445534	54	signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm entrainment of circadian clock negative regulation of transcription	Circadian rhythm - mammal
209020_at	-0.511	7.971	-4.023	1.079e-03	0.150	-0.631	C20orf111	chromosome 20 open reading frame 111	20	-42258549	AF217514	51526	20q13.11	Hs.75798	6
235261_at	-0.539	10.438	-4.022	1.080e-03	0.150	-0.632	UNC45B	unc-45 homolog B (C. elegans)	17	30498948	AI800785	146862	17q12	Hs.379636	4	binding multicellular organismal development muscle organ development cell differentiation
229377_at	-0.511	5.872	-4.021	1.083e-03	0.150	-0.635	GRTP1	growth hormone regulated TBC protein 1	13	-113026505	BF001483	79774	13q34	Hs.170904	3	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
208913_at	-0.579	7.188	-4.018	1.090e-03	0.151	-0.640	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	16	-23383143	AA868560	23062	16p12	Hs.460336	37	protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding	Lysosome
201376_s_at	-0.405	6.523	-4.017	1.092e-03	0.151	-0.642	HNRNPF	heterogeneous nuclear ribonucleoprotein F	10	-43201070, -43201070, -43201070, -43201070, -43201070, -43201070	AI591354	3185	10q11.21-q11.22	Hs.712955 Hs.808	30	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm heterogeneous nuclear ribonucleoprotein complex regulation of RNA splicing
230040_at	0.853	3.671	4.014	1.097e-03	0.151	-0.646	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	16	-75873525	AI733120	170692	16q23	Hs.188746	9	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
221058_s_at	0.403	5.747	4.013	1.100e-03	0.151	-0.649	CKLF	chemokine-like factor	16	65143966, 65143972	NM_016326	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
1559496_at	0.730	4.982	4.013	1.102e-03	0.151	-0.650	PPA2	pyrophosphatase (inorganic) 2	4	-106509682	AL833123	27068	4q25	Hs.654957	13	magnesium ion binding inorganic diphosphatase activity cytoplasm mitochondrion phosphate metabolic process hydrolase activity	Oxidative phosphorylation
221567_at	-0.356	8.126	-4.011	1.105e-03	0.151	-0.652	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	16	65765370	AF064599	8996	16q21-q23	Hs.513667	22	RNA binding intracellular nucleus nucleolus cytoplasm cytosol mRNA processing anti-apoptosis RNA splicing identical protein binding regulation of apoptosis
243439_at	0.551	5.722	4.005	1.118e-03	0.152	-0.663	ZNF418	zinc finger protein 418	19	-63125063	AI971569	147686	19q13.43	Hs.660728	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226229_s_at	0.405	5.867	4.003	1.123e-03	0.153	-0.667	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	BF510732	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
205771_s_at	-1.024	7.942	-3.998	1.134e-03	0.154	-0.676	AKAP7	A kinase (PRKA) anchor protein 7	6	131508153, 131613196	AL137063	9465	6q23	Hs.486483	9	catalytic activity intracellular cytoplasm cytosol plasma membrane ion transport intracellular signaling cascade protein localization biological_process RNA metabolic process apical plasma membrane lateral plasma membrane protein kinase A binding protein kinase A binding
203367_at	0.363	6.604	3.993	1.146e-03	0.155	-0.686	DUSP14	dual specificity phosphatase 14	17	32924063	NM_007026	11072	17q12	Hs.91448	5	protein tyrosine phosphatase activity protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
218676_s_at	-0.452	6.714	-3.991	1.152e-03	0.155	-0.690	PCTP	phosphatidylcholine transfer protein	17	51183354	NM_021213	58488	17q21-q24	Hs.285218	9	cytoplasm cytosol cytosol lipid binding phosphatidylcholine transmembrane transporter activity phosphatidylcholine transmembrane transporter activity phospholipid transport phosphatidylcholine binding
225381_at	0.788	5.988	3.988	1.159e-03	0.156	-0.695	LOC399959	hypothetical LOC399959	11	-121465022	AW162210	399959	11q24.1	Hs.44098	2
214179_s_at	-0.536	10.811	-3.985	1.165e-03	0.156	-0.700	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	H93013	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
219963_at	-0.501	10.097	-3.978	1.181e-03	0.158	-0.713	DUSP13	dual specificity phosphatase 13	10	-76524197, -76524195	NM_016364	51207	10q22.2	Hs.178170	9	protein tyrosine phosphatase activity protein amino acid dephosphorylation meiosis spermatogenesis protein tyrosine/serine/threonine phosphatase activity hydrolase activity
225071_at	-0.498	6.013	-3.976	1.188e-03	0.158	-0.717	NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	6	118103309	BG168247	116150	6q22.1	Hs.289008	6	angiogenesis molecular_function receptor activity cellular_component multicellular organismal development biological_process membrane integral to membrane transferase activity, transferring alkyl or aryl (other than methyl) groups cell differentiation
207550_at	0.427	3.170	3.975	1.190e-03	0.158	-0.719	MPL	myeloproliferative leukemia virus oncogene	1	43576061	NM_005373	4352	1p34	Hs.82906	85	cytokine receptor activity plasma membrane integral to plasma membrane cell surface receptor linked signal transduction cell proliferation	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
212814_at	0.528	7.449	3.966	1.211e-03	0.160	-0.735	AHCYL2	adenosylhomocysteinase-like 2	7	128652099, 128795217	AB020635	23382	7q32.1	Hs.600789	5	adenosylhomocysteinase activity binding one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
222408_s_at	-0.506	8.246	-3.963	1.220e-03	0.161	-0.741	YPEL5	yippee-like 5 (Drosophila)	2	30223253	BC000836	51646	2p23.1	Hs.515890	6
202041_s_at	0.479	8.116	3.959	1.229e-03	0.162	-0.748	FIBP	fibroblast growth factor (acidic) intracellular binding protein	11	-65407786	NM_004214	9158	11q13.1	Hs.7768	10	protein binding membrane fraction nucleus mitochondrion fibroblast growth factor receptor signaling pathway membrane fibroblast growth factor binding
226707_at	0.538	6.513	3.956	1.236e-03	0.162	-0.753	NAPRT1	nicotinate phosphoribosyltransferase domain containing 1	8	-144728097	AI925574	93100	8q24.3	Hs.493164	3	nicotinate phosphoribosyltransferase activity cytoplasm cytosol response to oxidative stress transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process
219461_at	0.363	4.916	3.952	1.246e-03	0.163	-0.761	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	15	38296920, 38319326	AJ236915	56924	15q14	Hs.513645	13	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
219090_at	-1.202	7.810	-3.943	1.269e-03	0.165	-0.777	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	20	19141289	NM_020689	57419	20p13	Hs.654790	2	calcium ion binding ion transport potassium ion transport sodium ion transport calcium ion transport calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral to membrane potassium ion binding sodium ion binding
202760_s_at	1.129	6.045	3.936	1.289e-03	0.167	-0.791	PALM2-AKAP2	PALM2-AKAP2 readthrough transcript	9	111582397, 111582409	NM_007203	445815	9q31-q33	Hs.591908	8
219368_at	0.880	4.447	3.931	1.302e-03	0.169	-0.800	NAP1L2	nucleosome assembly protein 1-like 2	X	-72348878	NM_021963	4674	Xq13	Hs.66180 Hs.719281	4	nucleus chromatin assembly complex nucleosome assembly
213844_at	0.453	6.527	3.927	1.312e-03	0.170	-0.807	HOXA5	homeobox A5	7	-27147520	NM_019102	3202	7p15-p14	Hs.655218	32	transcription factor activity nucleus regulation of transcription, DNA-dependent pattern specification process anterior/posterior pattern formation lung development thyroid gland development multicellular organism growth sequence-specific DNA binding embryonic skeletal system morphogenesis
239629_at	0.843	7.850	3.923	1.324e-03	0.170	-0.815	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	AI634046	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
203051_at	-0.272	6.643	-3.922	1.326e-03	0.170	-0.816	BAHD1	bromo adjacent homology domain containing 1	15	38520702	NM_014952	22893	15q15.1	Hs.22109	5	DNA binding
214030_at	-0.374	7.447	-3.919	1.333e-03	0.170	-0.822	CRYBG3	beta-gamma crystallin domain containing 3	3	99078508	BE501352	131544	3q11.2	Hs.714457	2	sugar binding
229109_s_at	0.300	5.161	3.918	1.338e-03	0.171	-0.825	BLVRA	biliverdin reductase A	7	43764796	N21095	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
241370_at	-0.652	7.686	-3.910	1.358e-03	0.172	-0.838	LOC286052	hypothetical protein LOC286052	8		AA278233	286052	8q24.13	Hs.100691	1
222478_at	-0.447	7.940	-3.909	1.362e-03	0.172	-0.840	VPS36	vacuolar protein sorting 36 homolog (S. cerevisiae)	13	-51884737	AL576924	51028	13q14.3	Hs.109520	11	nucleus cytoplasm lysosome late endosome lipid binding protein transport ubiquitin binding regulation of transcription	Endocytosis
212253_x_at	-0.390	7.883	-3.906	1.370e-03	0.173	-0.846	DST	dystonin	6	-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743	BG253119	667	6p12.1	Hs.631992 Hs.669931	48	actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding
214439_x_at	-0.516	10.906	-3.902	1.381e-03	0.174	-0.853	BIN1	bridging integrator 1	2	-127522077, -127522076	AF043899	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
224791_at	0.569	6.646	3.899	1.391e-03	0.174	-0.860	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	8	-131133534	AW513835	50807	8q24.1-q24.2	Hs.655552	19	protein binding cytoplasm ARF GTPase activator activity zinc ion binding membrane regulation of ARF GTPase activity metal ion binding	Endocytosis Fc gamma R-mediated phagocytosis
229656_s_at	0.920	4.706	3.898	1.392e-03	0.174	-0.860	EML6	echinoderm microtubule associated protein like 6	2	54805652	AA236463	400954	2p16.2-p16.1	Hs.656692		cytoplasm microtubule
223299_at	0.389	7.028	3.898	1.392e-03	0.174	-0.861	SEC11C	SEC11 homolog C (S. cerevisiae)	18	54958104	AF212233	90701	18q21.32	Hs.45107	2	endoplasmic reticulum microsome signal peptide processing proteolysis peptidase activity membrane integral to membrane	Protein export
200804_at	-0.487	9.253	-3.898	1.393e-03	0.174	-0.861	TMBIM6	transmembrane BAX inhibitor motif containing 6	12	48421559, 48421858	NM_003217	7009	12q12-q13	Hs.35052 Hs.708025	20	insoluble fraction nucleus endoplasmic reticulum integral to plasma membrane spermatogenesis membrane negative regulation of apoptosis
220419_s_at	-0.653	9.493	-3.897	1.396e-03	0.174	-0.863	USP25	ubiquitin specific peptidase 25	21	16024366	NM_013396	29761	21q11.2	Hs.473370	11	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
203752_s_at	-0.583	8.942	-3.894	1.405e-03	0.175	-0.869	JUND	jun D proto-oncogene	19	-18251562	NM_005354	3727	19p13.2	Hs.2780	67	chromatin osteoblast development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding positive regulation of osteoblast differentiation protein dimerization activity	MAPK signaling pathway
208884_s_at	-0.565	7.241	-3.893	1.408e-03	0.175	-0.870	UBR5	ubiquitin protein ligase E3 component n-recognin 5	8	-103334744	AF006010	51366	8q22	Hs.591856	21	RNA binding ubiquitin-protein ligase activity protein binding intracellular soluble fraction nucleus protein modification process ubiquitin-dependent protein catabolic process response to DNA damage stimulus zinc ion binding cell proliferation ligase activity acid-amino acid ligase activity metal ion binding progesterone receptor signaling pathway	Ubiquitin mediated proteolysis
238149_at	0.557	2.307	3.891	1.413e-03	0.175	-0.873	ZNF818P	zinc finger protein 818 pseudogene	19		AI651641	390963	19q13.42	Hs.444446		DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
201041_s_at	-1.164	8.097	-3.882	1.440e-03	0.177	-0.891	DUSP1	dual specificity phosphatase 1	5	-172127706	NM_004417	1843	5q34	Hs.171695	73	non-membrane spanning protein tyrosine phosphatase activity protein binding protein amino acid dephosphorylation response to oxidative stress cell cycle intracellular signaling cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
208649_s_at	-0.364	8.396	-3.882	1.441e-03	0.177	-0.891	VCP	valosin-containing protein	9	-35046064	AF100752	7415	9p13.3	Hs.529782	97	nucleotide binding ATP binding nucleus nucleus nucleolus cytoplasm endoplasmic reticulum microsome cytosol double-strand break repair transport activation of caspase activity response to DNA damage stimulus lipid binding protein ubiquitination hydrolase activity ATPase activity protein domain specific binding modification-dependent protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol regulation of apoptosis establishment of protein localization
206843_at	-0.356	4.409	-3.881	1.442e-03	0.177	-0.892	CRYBA4	crystallin, beta A4	22	25347927	NM_001886	1413	22q11.2-q13.1 22q12.1	Hs.57690	13	molecular_function structural constituent of eye lens soluble fraction visual perception visual perception camera-type eye development
200789_at	0.483	10.678	3.880	1.446e-03	0.177	-0.895	ECH1	enoyl Coenzyme A hydratase 1, peroxisomal	19	-43997901	NM_001398	1891	19q13.1	Hs.196176	9	enoyl-CoA hydratase activity protein binding mitochondrion peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process isomerase activity	Tyrosine metabolism
205910_s_at	0.366	2.909	3.879	1.448e-03	0.177	-0.896	CEL	carboxyl ester lipase (bile salt-stimulated lipase)	9	134927185	NM_001807	1056	9q34.3	Hs.533258	51	sterol esterase activity sterol esterase activity triacylglycerol lipase activity extracellular region cytoplasm triglyceride metabolic process cholesterol catabolic process cholesterol catabolic process heparin binding fatty acid catabolic process lipid catabolic process hydrolase activity protein amino acid esterification pancreatic juice secretion intestinal cholesterol absorption intestinal lipid catabolic process acylglycerol lipase activity	Steroid biosynthesis Glycerolipid metabolism Metabolic pathways
222405_at	0.297	6.985	3.877	1.453e-03	0.177	-0.899	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	15	63609879	AL573951	51495	15q22.2	Hs.512973	13	molecular_function GTPase activator activity protein binding cellular_component I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity small GTPase mediated signal transduction Rho protein signal transduction membrane integral to membrane Rac protein signal transduction
215024_at	0.535	4.386	3.874	1.463e-03	0.178	-0.905	C7orf28B	chromosome 7 open reading frame 28B	7	-6805096	AK000993	221960	7p22.1	Hs.567779	5
235944_at	1.085	5.508	3.874	1.463e-03	0.178	-0.905	HMCN1	hemicentin 1	1	183970305	BF446673	83872	1q25.3-q31.1	Hs.58877	14	calcium ion binding extracellular region basement membrane visual perception bioluminescence protein-chromophore linkage response to stimulus
244024_at	-0.338	4.278	-3.872	1.469e-03	0.178	-0.909	ZNF182	zinc finger protein 182	X	-47719193	T67481	7569	Xp22.11-p11.23	Hs.189690	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202985_s_at	-0.386	6.914	-3.870	1.477e-03	0.179	-0.914	BAG5	BCL2-associated athanogene 5	14	-103092641, -103092641, -103092641	NM_004873	9529	14q32.33	Hs.5443	10	protein binding protein folding apoptosis
239261_s_at	0.349	4.830	3.868	1.480e-03	0.179	-0.916	CORIN	corin, serine peptidase	4	-47290774	AI338960	10699	4p13-p12	Hs.518618	15	serine-type endopeptidase activity scavenger receptor activity plasma membrane integral to plasma membrane proteolysis lipid metabolic process regulation of blood pressure peptidase activity anatomical structure morphogenesis cell surface
221942_s_at	0.553	6.729	3.863	1.497e-03	0.180	-0.926	GUCY1A3	guanylate cyclase 1, soluble, alpha 3	4	156807311, 156807311, 156807311, 156807598, 156807598, 156808264	AI719730	2982	4q31.1-q31.2 4q31.3-q33	Hs.24258	14	nucleotide binding guanylate cyclase activity receptor activity GTP binding cytoplasm nitric oxide mediated signal transduction guanylate cyclase complex, soluble regulation of blood pressure positive regulation of cGMP biosynthetic process response to defense-related host nitric oxide production relaxation of vascular smooth muscle	Purine metabolism Vascular smooth muscle contraction Gap junction Long-term depression
233438_at	0.491	4.141	3.862	1.501e-03	0.180	-0.928	C6orf162	chromosome 6 open reading frame 162	6	88089024	AK024130	57150	6q15-q16.1	Hs.70769	4	membrane integral to membrane
211382_s_at	-0.555	9.133	-3.862	1.502e-03	0.180	-0.929	TACC2	transforming, acidic coiled-coil containing protein 2	10	123738678, 123913094	AF220152	10579	10q26	Hs.501252 Hs.713875	18	protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding
1554966_a_at	-0.763	7.394	-3.860	1.506e-03	0.180	-0.931	FILIP1L	filamin A interacting protein 1-like	3	-101049461, -101049461, -101034677	AF329092	11259	3q12.1	Hs.104672	8	molecular_function nucleus cytoplasm biological_process membrane myosin complex
203511_s_at	0.434	7.452	3.856	1.518e-03	0.181	-0.939	TRAPPC3	trafficking protein particle complex 3	1	-36374759	AF041432	27095	1p34.3	Hs.523131	16	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol ER to Golgi vesicle-mediated transport vesicle-mediated transport TRAPP complex
206404_at	0.906	6.003	3.855	1.522e-03	0.181	-0.941	FGF9	fibroblast growth factor 9 (glia-activating factor)	13	21143214	NM_002010	2254	13q11-q12	Hs.111	33	angiogenesis osteoblast differentiation positive regulation of mesenchymal cell proliferation chondrocyte differentiation extracellular region extracellular region extracellular space protein import into nucleus signal transduction cell-cell signaling growth factor activity heparin binding male gonad development negative regulation of Wnt receptor signaling pathway male sex determination lung development embryonic limb morphogenesis positive regulation of vascular endothelial growth factor receptor signaling pathway inner ear morphogenesis positive regulation of MAPKKK cascade positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of smoothened signaling pathway regulation of timing of cell differentiation embryonic gut development embryonic skeletal system development positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
226925_at	0.682	5.058	3.852	1.530e-03	0.181	-0.945	ACPL2	acid phosphatase-like 2	3	142433371	AW069729	92370	3q23	Hs.657887	2	acid phosphatase activity extracellular region hydrolase activity
227583_at	-0.268	5.526	-3.851	1.536e-03	0.181	-0.949	POP4	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	19	34789009	BE742653	10775	19q12	Hs.412870	13	ribonuclease MRP complex RNA binding ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolus rRNA processing mRNA cleavage tRNA processing hydrolase activity ribonuclease P complex identical protein binding
1554154_at	0.369	5.272	3.850	1.537e-03	0.181	-0.949	GDAP2	ganglioside induced differentiation associated protein 2	1	-118221367, -118207630	BC013132	54834	1p12	Hs.310809 Hs.594430	3
217882_at	-0.599	10.571	-3.847	1.548e-03	0.181	-0.956	TMEM111	transmembrane protein 111	3	-9980635	NM_018447	55831	3p25.3	Hs.475392	6	molecular_function cellular_component biological_process membrane integral to membrane
1557165_s_at	0.805	8.697	3.845	1.552e-03	0.181	-0.958	KLHL18	kelch-like 18 (Drosophila)	3	47299333	BM141828	23276	3p21.31	Hs.517946	8	protein binding
201591_s_at	0.352	7.508	3.845	1.553e-03	0.181	-0.959	NISCH	nischarin	3	52464563	NM_007184	11188	3p21.1	Hs.435290	16	receptor activity integrin binding protein binding membrane fraction cytoplasm early endosome cytosol plasma membrane glucose metabolic process apoptosis cell communication regulation of blood pressure amine receptor activity Rac protein signal transduction actin cytoskeleton organization negative regulation of cell migration regulation of synaptic transmission, GABAergic phosphoinositide binding norepinephrine secretion recycling endosome
201121_s_at	0.496	7.839	3.845	1.553e-03	0.181	-0.959	PGRMC1	progesterone receptor membrane component 1	X	118254238	NM_006667	10857	Xq22-q24	Hs.90061	26	receptor activity steroid binding protein binding nucleus nucleolus endoplasmic reticulum microsome cell surface membrane integral to membrane heme binding
1556601_a_at	0.335	4.468	3.833	1.592e-03	0.185	-0.981	SPATA13	spermatogenesis associated 13	13	23632886	R69077	221178	13q12.12	Hs.657121	7	Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
202289_s_at	-0.494	10.658	-3.832	1.594e-03	0.185	-0.983	TACC2	transforming, acidic coiled-coil containing protein 2	10	123738678, 123913094	NM_006997	10579	10q26	Hs.501252 Hs.713875	18	protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding
1552731_at	-1.622	8.049	-3.828	1.608e-03	0.186	-0.990	ABRA	actin-binding Rho activating protein	8	-107840886	NM_139166	137735	8q23.1	Hs.374668	12	protein import into nucleus, translocation transcription coactivator activity actin binding cytoplasm plasma membrane protein transport actin cytoskeleton sarcomere positive regulation of Rho protein signal transduction positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription factor activity intracellular protein transmembrane transport
222404_x_at	0.480	7.055	3.828	1.610e-03	0.186	-0.991	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	15	63609879	AI984229	51495	15q22.2	Hs.512973	13	molecular_function GTPase activator activity protein binding cellular_component I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity small GTPase mediated signal transduction Rho protein signal transduction membrane integral to membrane Rac protein signal transduction
229340_at	-0.357	5.796	-3.821	1.632e-03	0.188	-1.004	NKAPL	NFKB activating protein-like	6	28335076	BF592882	222698	6p22.1	Hs.239181	3
211761_s_at	-0.390	9.436	-3.813	1.658e-03	0.190	-1.018	CACYBP	calcyclin binding protein	1	173235193, 173235514	BC005975	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
235374_at	0.465	7.590	3.812	1.664e-03	0.190	-1.021	MDH1	malate dehydrogenase 1, NAD (soluble)	2	63669625	AW952547	4190	2p13.3	Hs.526521	18	malic enzyme activity binding soluble fraction cytoplasm cytosol cytosol glycolysis tricarboxylic acid cycle oxaloacetate metabolic process malate metabolic process oxidoreductase activity NAD metabolic process L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
224759_s_at	0.410	6.947	3.811	1.667e-03	0.190	-1.023	C12orf23	chromosome 12 open reading frame 23	12	105873673	AK001731	90488	12q23.3	Hs.257664	3	membrane integral to membrane
230708_at	0.349	4.821	3.804	1.692e-03	0.192	-1.036	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	AA206141	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
233899_x_at	-0.427	4.735	-3.799	1.708e-03	0.193	-1.045	ZBTB10	zinc finger and BTB domain containing 10	8	81561002	AK024296	65986	8q13-q21.1	Hs.591868	4	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
222413_s_at	0.677	6.180	3.799	1.709e-03	0.193	-1.045	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	7	-151462942	AW137099	58508	7q36.1	Hs.647120	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent intracellular signaling cascade methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
206303_s_at	-0.504	6.900	-3.795	1.723e-03	0.193	-1.052	NUDT4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	12	92295831	AF191653	11163	12q21	Hs.506325	10	magnesium ion binding intracellular cytoplasm intracellular signaling cascade diphosphoinositol-polyphosphate diphosphatase activity cyclic nucleotide metabolic process hydrolase activity calcium-mediated signaling cyclic-nucleotide-mediated signaling manganese ion binding regulation of RNA export from nucleus intracellular transport
214709_s_at	-0.478	11.707	-3.794	1.725e-03	0.193	-1.053	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	Z22551	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
203685_at	-0.845	7.488	-3.794	1.725e-03	0.193	-1.053	BCL2	B-cell CLL/lymphoma 2	18	-59136166, -58941558	NM_000633	596	18q21.3 18q21.33	Hs.150749	705	G1/S transition of mitotic cell cycle protein phosphatase type 2A complex cell morphogenesis response to acid ovarian follicle development ureteric bud development branching involved in ureteric bud morphogenesis behavioral fear response response to hypoxia B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development renal system process intracellular membrane fraction nucleus cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol calcineurin complex protein amino acid dephosphorylation melanin metabolic process oxygen and reactive oxygen species metabolic process regulation of nitrogen utilization anti-apoptosis humoral immune response response to oxidative stress actin filament organization female pregnancy cell aging response to nutrient transcription factor binding cell death positive regulation of cell proliferation male gonad development activation of pro-apoptotic gene products response to radiation response to heat response to external stimulus response to toxin post-embryonic development organ morphogenesis response to inorganic substance response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration membrane integral to membrane cell-cell adhesion transcription activator activity peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis hemopoiesis negative regulation of ossification negative regulation of cell growth negative regulation of cell migration response to caffeine hair follicle morphogenesis axon regeneration regulation of protein stability nuclear membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization negative regulation of myeloid cell apoptosis T cell differentiation in the thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine stimulus response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation response to drug response to hydrogen peroxide protein homodimerization activity T cell homeostasis positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment response to peptide hormone stimulus regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis ear development response to estrogen stimulus regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability protein heterodimerization activity focal adhesion formation positive regulation of pigmentation during development spleen development thymus development gut morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue response to glucocorticoid stimulus BH3 domain binding defense response to virus regulation of cell cycle response to protein stimulus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport apoptosis in response to endoplasmic reticulum stress	Apoptosis Focal adhesion Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Prostate cancer Small cell lung cancer
1554553_s_at	0.284	5.844	3.791	1.737e-03	0.194	-1.060	YIF1B	Yip1 interacting factor homolog B (S. cerevisiae)	19	-43486039, -43486039, -43486039	BC014974	90522	19q13.2	Hs.280741 Hs.631544	4	membrane integral to membrane
203234_at	0.476	6.482	3.790	1.740e-03	0.194	-1.061	UPP1	uridine phosphorylase 1	7	48094879, 48095270	NM_003364	7378	7p12.3	Hs.488240	11	uridine phosphorylase activity uridine phosphorylase activity cytoplasm cytosol nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine nucleotide metabolic process nucleoside metabolic process nucleotide catabolic process uridine metabolic process	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways
229477_at	0.946	5.507	3.788	1.748e-03	0.194	-1.065	THRSP	thyroid hormone responsive (SPOT14 homolog, rat)	11	77452554	AW272342	7069	11q13.5	Hs.591969	12	protein binding nucleus lipid metabolic process
229476_s_at	1.068	6.260	3.787	1.749e-03	0.194	-1.066	THRSP	thyroid hormone responsive (SPOT14 homolog, rat)	11	77452554	AW272342	7069	11q13.5	Hs.591969	12	protein binding nucleus lipid metabolic process
213645_at	-1.064	6.686	-3.786	1.753e-03	0.194	-1.068	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	AF305057	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
228624_at	0.382	4.156	3.785	1.759e-03	0.194	-1.071	TMEM144	transmembrane protein 144	4	159350850	AI432488	55314	4q32.1	Hs.718582	2	membrane integral to membrane
224574_at	0.539	7.094	3.783	1.766e-03	0.195	-1.074	C17orf49	chromosome 17 open reading frame 49	17	6858796	AV759602	124944	17p13.1	Hs.511801	7	DNA binding nucleus
231969_at	0.747	6.188	3.782	1.769e-03	0.195	-1.076	STOX2	storkhead box 2	4	185063502	AB037813	56977	4q35.1	Hs.21958 Hs.696657	3
212427_at	-0.801	7.057	-3.780	1.775e-03	0.195	-1.079	KIAA0368	KIAA0368	9	-113162793	AB002366	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
219825_at	0.846	4.693	3.780	1.777e-03	0.195	-1.080	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1	2	-72209874	NM_019885	56603	2p13.2	Hs.91546	11	cell fate determination retinoic acid binding endoplasmic reticulum microsome male meiosis spermatogenesis retinoic acid 4-hydroxylase activity electron carrier activity proximal/distal pattern formation membrane heme binding embryonic limb morphogenesis retinoic acid catabolic process metal ion binding negative regulation of retinoic acid receptor signaling pathway oxidation reduction	Retinol metabolism
229085_at	-1.923	5.389	-3.776	1.791e-03	0.195	-1.087	LRRC3B	leucine rich repeat containing 3B	3	26639303	AW027879	116135	3p24	Hs.517868	10	protein binding membrane integral to membrane
1567064_at	-0.270	3.107	-3.775	1.795e-03	0.195	-1.089	OR1Q1	olfactory receptor, family 1, subfamily Q, member 1	9	124416837	X89667	158131	9q33.2	Hs.684864	3	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
208086_s_at	-0.502	5.055	-3.771	1.808e-03	0.196	-1.096	DMD	dystrophin	X	-31106232, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265	M92650	1756	Xp21.2	Hs.495912	240	actin binding structural constituent of cytoskeleton calcium ion binding protein binding cytoplasm cytoskeleton muscle organ development zinc ion binding structural constituent of muscle structural constituent of muscle cell surface dystrophin-associated glycoprotein complex sarcolemma costamere peptide biosynthetic process nitric-oxide synthase binding	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
218546_at	0.592	6.346	3.768	1.821e-03	0.197	-1.102	C1orf115	chromosome 1 open reading frame 115	1	218930250	NM_024709	79762	1q41	Hs.519839	6	membrane integral to membrane
205079_s_at	-0.437	7.872	-3.767	1.825e-03	0.197	-1.104	MPDZ	multiple PDZ domain protein	9	-13095702	NM_003829	8777	9p24-p22	Hs.169378	25	protein binding plasma membrane tight junction postsynaptic density synaptosome cell junction dendrite cell projection interspecies interaction between organisms synapse postsynaptic membrane	Tight junction
212055_at	0.576	5.458	3.763	1.839e-03	0.198	-1.111	C18orf10	chromosome 18 open reading frame 10	18	-32630031	BF689173	25941	18q12.2	Hs.695999	5	cytoplasm cytoskeleton microtubule
209014_at	0.586	8.529	3.758	1.859e-03	0.200	-1.121	MAGED1	melanoma antigen family D, 1	X	51562894, 51653437	AF217963	9500	Xp11.23	Hs.5258	29	transcription coactivator activity cytoplasm plasma membrane regulation of transcription from RNA polymerase II promoter identical protein binding regulation of apoptosis protein complex negative regulation of epithelial cell proliferation	Neurotrophin signaling pathway
209083_at	0.383	5.443	3.750	1.891e-03	0.201	-1.136	CORO1A	coronin, actin binding protein, 1A	16	30102426	U34690	11151	16p11.2	Hs.415067	23	immunological synapse phagolysosome formation phagocytic cup nucleus cytoplasm plasma membrane cell cortex calcium ion transport cell motion actin filament organization protein C-terminus binding regulation of cell shape lamellipodium positive regulation of cell migration leukocyte chemotaxis phagocytic vesicle membrane regulation of actin filament polymerization cortical actin cytoskeleton cytoplasmic vesicle cell-substrate adhesion filamentous actin uropod organization response to cytokine stimulus positive regulation of T cell proliferation protein homodimerization activity T cell homeostasis phosphoinositide 3-kinase binding innate immune response homeostasis of number of cells within a tissue positive chemotaxis actin filament binding negative regulation of actin nucleation
204264_at	0.704	7.437	3.748	1.895e-03	0.201	-1.138	CPT2	carnitine palmitoyltransferase 2	1	53434688	NM_000098	1376	1p32	Hs.713535	53	carnitine O-palmitoyltransferase activity carnitine O-palmitoyltransferase activity mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport carnitine shuttle acyltransferase activity membrane transferase activity regulation of fatty acid oxidation	Fatty acid metabolism PPAR signaling pathway
63009_at	0.303	6.412	3.748	1.899e-03	0.201	-1.140	SHQ1	SHQ1 homolog (S. cerevisiae)	3	-72881117	AI188402	55164	3p13	Hs.606584	2
235301_at	0.561	5.912	3.747	1.900e-03	0.201	-1.140	KIAA1324L	KIAA1324-like	7	-86347173, -86347173	AI797353	222223	7q21.12	Hs.208093	3	G-protein coupled receptor activity protein binding G-protein coupled receptor protein signaling pathway membrane integral to membrane
1558668_s_at	0.534	2.445	3.745	1.909e-03	0.201	-1.145	SPATA22	spermatogenesis associated 22	17	-3290063	AW072392	84690	17p13.3	Hs.351068	3
224918_x_at	1.427	6.884	3.745	1.911e-03	0.201	-1.146	MGST1	microsomal glutathione S-transferase 1	12	16391342, 16391845, 16391978, 16397617	AI220117	4257	12p12.3-p12.1	Hs.389700	22	glutathione transferase activity mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum microsome glutathione metabolic process membrane transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
229770_at	0.560	6.353	3.744	1.912e-03	0.201	-1.146	GLT1D1	glycosyltransferase 1 domain containing 1	12	127904033	AI041543	144423	12q24.33	Hs.655668	6	extracellular region biosynthetic process transferase activity, transferring glycosyl groups
204234_s_at	-0.612	5.164	-3.744	1.914e-03	0.201	-1.147	ZNF195	zinc finger protein 195	11	-3336586	AI476267	7748	11p15.5	Hs.386294	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201161_s_at	-0.482	12.823	-3.743	1.915e-03	0.201	-1.147	CSDA	cold shock domain protein A	12	-10742944	NM_003651	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
205917_at	0.394	6.151	3.739	1.932e-03	0.203	-1.156	ZNF264	zinc finger protein 264	19	62394680	NM_003417	9422	19q13.4	Hs.515634	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213929_at	0.499	2.932	3.738	1.935e-03	0.203	-1.157	EXPH5	exophilin 5	11	-107881367, -107881367, -107881367	AL050204	23086	11q22.3	Hs.28540	8	protein binding intracellular protein transport Rab GTPase binding
231736_x_at	1.348	6.514	3.736	1.946e-03	0.203	-1.162	MGST1	microsomal glutathione S-transferase 1	12	16391342, 16391845, 16391978, 16397617	NM_020300	4257	12p12.3-p12.1	Hs.389700	22	glutathione transferase activity mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum microsome glutathione metabolic process membrane transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
1565162_s_at	1.786	4.909	3.735	1.948e-03	0.203	-1.163	MGST1	microsomal glutathione S-transferase 1	12	16391342, 16391845, 16391978, 16397617	D16947	4257	12p12.3-p12.1	Hs.389700	22	glutathione transferase activity mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum microsome glutathione metabolic process membrane transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
215102_at	0.365	4.330	3.735	1.949e-03	0.203	-1.163	DPY19L1P1	dpy-19-like 1 pseudogene 1 (C. elegans)	7		AK026768	100129460	7p14.3	Hs.633705
219505_at	0.656	6.139	3.730	1.968e-03	0.204	-1.172	CECR1	cat eye syndrome chromosome region, candidate 1	22	-16040193, -16040191	NM_017424	51816	22q11.2	Hs.170310	10	extracellular region extracellular space Golgi apparatus multicellular organismal development growth factor activity purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity
225801_at	-1.397	5.913	-3.728	1.976e-03	0.204	-1.176	FBXO32	F-box protein 32	8	-124584538, -124584538	AW518714	114907	8q24.13	Hs.403933	17	protein binding modification-dependent protein catabolic process
200924_s_at	-0.433	6.644	-3.728	1.977e-03	0.204	-1.176	SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	11	62380093, 62404862	NM_002394	6520	11q13	Hs.502769	74	catalytic activity calcium:sodium antiporter activity protein binding protein binding plasma membrane carbohydrate metabolic process transport calcium ion transport amino acid transport cell surface neutral amino acid transmembrane transporter activity tryptophan transport integral to membrane cell growth melanosome cation binding leucine import
214726_x_at	-0.261	6.791	-3.723	1.998e-03	0.206	-1.186	ADD1	adducin 1 (alpha)	4	2815381	AL556041	118	4p16.3	Hs.183706 Hs.701490	139	calmodulin binding nucleus cytoplasm cytosol cytoskeleton plasma membrane transcription factor binding F-actin capping protein complex actin cytoskeleton organization spectrin binding positive regulation of protein binding protein homodimerization activity metal ion binding protein heterodimerization activity actin filament binding barbed-end actin filament capping actin filament bundle formation
218844_at	0.466	7.076	3.722	2.003e-03	0.206	-1.188	ACSF2	acyl-CoA synthetase family member 2	17	45858517	NM_025149	80221	17q21.33	Hs.288959	7	nucleotide binding ATP binding mitochondrion lipid metabolic process fatty acid metabolic process metabolic process ligase activity
224906_at	-0.478	8.706	-3.721	2.008e-03	0.206	-1.190	ANO6	anoctamin 6	12	43896036, 43896036, 43896142, 43972732	AL041280	196527	12q12	Hs.696326	6	ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex
1552430_at	0.280	2.228	3.719	2.015e-03	0.207	-1.193	WDR17	WD repeat domain 17	4	177224125	NM_170710	116966	4q34	Hs.532056	3
213787_s_at	0.463	6.315	3.717	2.024e-03	0.207	-1.197	EBP	emopamil binding protein (sterol isomerase)	X	48265107	AV702405	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
1563483_at	-0.578	4.036	-3.714	2.035e-03	0.207	-1.202	FAM91A2	family with sequence similarity 91, member A2	1		AB007962	57234	1q21.1	Hs.710717	3
229817_at	0.793	5.745	3.713	2.040e-03	0.207	-1.205	ZNF608	zinc finger protein 608	5	-124000508	AI452715	57507	5q23.2	Hs.266616	8	intracellular zinc ion binding metal ion binding
204998_s_at	1.560	6.902	3.703	2.083e-03	0.210	-1.223	ATF5	activating transcription factor 5	19	55123785	NM_012068	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
42361_g_at	0.512	4.416	3.701	2.088e-03	0.210	-1.225	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AI588986	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
229492_at	0.335	4.126	3.701	2.091e-03	0.210	-1.227	VANGL1	vang-like 1 (van gogh, Drosophila)	1	115986096	R85437	81839	1p11-p13.1	Hs.515130	12	protein binding multicellular organismal development membrane integral to membrane	Wnt signaling pathway
208173_at	-0.421	4.247	-3.700	2.095e-03	0.210	-1.228	IFNB1	interferon, beta 1, fibroblast	9	-21067103	NM_002176	3456	9p21	Hs.93177	127	transcription corepressor activity cytokine activity interferon-alpha/beta receptor binding extracellular region extracellular space induction of apoptosis activation of caspase activity activation of caspase activity cell surface receptor linked signal transduction negative regulation of cell proliferation response to virus natural killer cell activation negative regulation of viral transcription B cell proliferation defense response to bacterium positive regulation of innate immune response regulation of MHC class I biosynthetic process negative regulation of virion penetration into host cell	Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity
219848_s_at	0.491	5.699	3.697	2.107e-03	0.211	-1.234	ZNF432	zinc finger protein 432	19	-57228488	NM_014650	9668	19q13.41	Hs.655934	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201040_at	0.455	6.118	3.695	2.115e-03	0.211	-1.237	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	3	50248650	NM_002070	2771	3p21	Hs.77269	85	nucleotide binding activation of MAPKK activity adenosine receptor signaling pathway GTPase activity signal transducer activity protein binding GTP binding membrane fraction nucleus cytosol plasma membrane signal transduction inhibition of adenylate cyclase activity by G-protein signaling muscarinic acetylcholine receptor signaling pathway gamma-aminobutyric acid signaling pathway protein kinase cascade response to nutrient positive regulation of cell proliferation guanyl nucleotide binding membrane raft negative regulation of synaptic transmission negative regulation of calcium ion transport via voltage-gated calcium channel activity	Chemokine signaling pathway Axon guidance Tight junction Gap junction Leukocyte transendothelial migration Long-term depression Melanogenesis
200972_at	-0.579	10.380	-3.692	2.129e-03	0.212	-1.243	TSPAN3	tetraspanin 3	15	-75125385	BC000704	10099	15q24.3	Hs.5062 Hs.716484	8	membrane integral to membrane
228125_at	0.398	6.506	3.691	2.134e-03	0.212	-1.245	ZNF397OS	zinc finger protein 397 opposite strand	18	-31086816	BF431973	100101467	18q12.2	Hs.464896	3	transcription factor activity intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
227163_at	0.396	5.026	3.688	2.147e-03	0.212	-1.251	GSTO2	glutathione S-transferase omega 2	10	106018620	AL162742	119391	10q25.1	Hs.203634	27	glutathione transferase activity cytoplasm metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
213955_at	-0.916	10.162	-3.688	2.148e-03	0.212	-1.251	MYOZ3	myozenin 3	5	150020596	BE673151	91977	5q33.1	Hs.91626	7	protein binding cytoplasm Z disc
230206_at	-0.386	5.000	-3.683	2.168e-03	0.213	-1.259	DOCK5	dedicator of cytokinesis 5	8	25098203	AI692645	80005	8p21.2	Hs.195403	7	guanyl-nucleotide exchange factor activity cytoplasm
214959_s_at	-0.536	4.404	-3.682	2.172e-03	0.213	-1.261	API5	apoptosis inhibitor 5	11	43290080	AF229253	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
204813_at	0.493	5.818	3.682	2.175e-03	0.213	-1.262	MAPK10	mitogen-activated protein kinase 10	4	-87156655, -87156655, -87156655, -87156655	NM_002753	5602	4q22.1-q23	Hs.125503	54	nucleotide binding protein serine/threonine kinase activity JUN kinase activity MAP kinase activity MAP kinase kinase activity ATP binding cytoplasm protein amino acid phosphorylation signal transduction JNK cascade transferase activity	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Pancreatic cancer
1569157_s_at	0.753	4.499	3.680	2.183e-03	0.214	-1.266	ZNF846	zinc finger protein 846	19	-9729150	BC037359	162993	19p13.2	Hs.665717	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203765_at	0.552	3.772	3.678	2.191e-03	0.214	-1.269	GCA	grancalcin, EF-hand calcium binding protein	2	162908828	NM_012198	25801	2q24.2	Hs.377894	14	calcium ion binding cytoplasm plasma membrane membrane fusion
204720_s_at	0.977	3.220	3.676	2.202e-03	0.214	-1.274	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6	1	65503017	AV729634	9829	1pter-q31.3	Hs.647643	11	protein tyrosine phosphatase activity hydrolase activity SH3 domain binding heat shock protein binding	Endocytosis
215338_s_at	0.528	7.091	3.675	2.205e-03	0.214	-1.275	NKTR	natural killer-tumor recognition sequence	3	42617150	AI688640	4820	3p23-p21	Hs.529509	9	peptidyl-prolyl cis-trans isomerase activity protein folding cyclosporin A binding membrane isomerase activity
205839_s_at	0.442	5.250	3.672	2.217e-03	0.214	-1.279	BZRAP1	benzodiazapine receptor (peripheral) associated protein 1	17	-53733592	NM_004758	9256	17q22-q23	Hs.112499	6	cytoplasm mitochondrion biological_process benzodiazepine receptor binding
213831_at	1.736	3.957	3.672	2.218e-03	0.214	-1.280	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	6	32713160	X00452	3117	6p21.3	Hs.387679 Hs.706240	542	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane MHC class II receptor activity MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
231015_at	-1.025	8.272	-3.671	2.221e-03	0.214	-1.281	KLF15	Kruppel-like factor 15	3	-127544167	AW014734	28999	3q13-q21	Hs.272215	10	transcription factor activity protein binding intracellular nucleus zinc ion binding glucose transport regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding
222764_at	0.733	5.550	3.671	2.224e-03	0.214	-1.282	ASRGL1	asparaginase like 1	11	61861349	AI928342	80150	11q12.3	Hs.535326	9	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity cytoplasm hydrolase activity asparagine catabolic process via L-aspartate	Alanine, aspartate and glutamate metabolism Cyanoamino acid metabolism Nitrogen metabolism Metabolic pathways
219203_at	0.297	8.086	3.670	2.230e-03	0.214	-1.285	FAM158A	family with sequence similarity 158, member A	14	-23678013	NM_016049	51016	14q11.2	Hs.271614	4
203264_s_at	0.452	5.026	3.669	2.232e-03	0.214	-1.286	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9	X	-62771572	NM_015185	23229	Xq11.1	Hs.54697	10	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm regulation of Rho protein signal transduction
229745_x_at	-0.505	5.449	-3.664	2.256e-03	0.215	-1.295	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)	19	-51842708	AI468629	147906	19q13.32	Hs.515490	4
239178_at	0.579	2.287	3.664	2.257e-03	0.215	-1.296	FGF9	fibroblast growth factor 9 (glia-activating factor)	13	21143214	AL583692	2254	13q11-q12	Hs.111	33	angiogenesis osteoblast differentiation positive regulation of mesenchymal cell proliferation chondrocyte differentiation extracellular region extracellular region extracellular space protein import into nucleus signal transduction cell-cell signaling growth factor activity heparin binding male gonad development negative regulation of Wnt receptor signaling pathway male sex determination lung development embryonic limb morphogenesis positive regulation of vascular endothelial growth factor receptor signaling pathway inner ear morphogenesis positive regulation of MAPKKK cascade positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of smoothened signaling pathway regulation of timing of cell differentiation embryonic gut development embryonic skeletal system development positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
219418_at	-0.399	6.396	-3.661	2.268e-03	0.216	-1.300	NHEJ1	nonhomologous end-joining factor 1	2	-219648289	NM_024782	79840	2q35	Hs.225988	27	DNA binding nucleus DNA repair double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development response to ionizing radiation B cell differentiation T cell differentiation identical protein binding positive regulation of ligase activity	Non-homologous end-joining
233750_s_at	-0.683	5.204	-3.661	2.269e-03	0.216	-1.300	C1orf25	chromosome 1 open reading frame 25	1	-183353840	AL109865	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
201236_s_at	-1.171	8.144	-3.660	2.275e-03	0.216	-1.303	BTG2	BTG family, member 2	1	201541286	NM_006763	7832	1q32	Hs.519162	45	protein binding DNA repair protein amino acid methylation response to DNA damage stimulus negative regulation of cell proliferation anterior/posterior pattern formation neuron differentiation negative regulation of apoptosis regulation of transcription
207057_at	1.312	6.095	3.659	2.280e-03	0.216	-1.305	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	NM_004731	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
234937_x_at	0.430	4.384	3.658	2.284e-03	0.216	-1.306	ZFP28	zinc finger protein 28 homolog (mouse)	19	61742128	AC007228	140612		Hs.14794	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211721_s_at	0.390	3.175	3.657	2.289e-03	0.216	-1.308	ZNF551	zinc finger protein 551	19	62885168	BC005868	90233	19q13.43	Hs.109540	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
217781_s_at	-0.567	11.287	-3.656	2.295e-03	0.216	-1.310	ZFP106	zinc finger protein 106 homolog (mouse)	15	-40492312	NM_022473	64397	15q15.1	Hs.511143	9	opioid peptide activity intracellular membrane fraction nucleus nucleolus cytosol zinc ion binding insulin receptor signaling pathway SH3 domain binding metal ion binding
216843_x_at	0.333	6.238	3.653	2.308e-03	0.216	-1.316	PMS2L1	postmeiotic segregation increased 2-like 1 pseudogene	7	-99756198	U38964	5379	7q22.1	Hs.634244 Hs.661055 Hs.709266	7	molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding
210165_at	-0.347	5.083	-3.652	2.312e-03	0.216	-1.317	DNASE1	deoxyribonuclease I	16	3642940	M55983	1773	16p13.3	Hs.629638	48	actin binding endonuclease activity deoxyribonuclease I activity deoxyribonuclease activity calcium ion binding protein binding extracellular region nucleus nuclear envelope DNA catabolic process apoptosis hydrolase activity
231950_at	0.478	4.964	3.649	2.324e-03	0.216	-1.322	ZNF658	zinc finger protein 658	9	-40761401	AW874634	26149	9p13.1	Hs.522147	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
205529_s_at	0.525	5.509	3.649	2.326e-03	0.216	-1.323	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	8	-93040327, -93040327, -93040327, -93040327	NM_004349	862	8q22	Hs.368431	85	transcription factor activity protein binding nucleus generation of precursor metabolites and energy regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity protein homodimerization activity fat cell differentiation metal ion binding regulation of DNA binding	Pathways in cancer Acute myeloid leukemia
226549_at	0.401	7.461	3.647	2.335e-03	0.217	-1.326	SBK1	SH3-binding domain kinase 1	16	28211340	BF447901	388228	16p11.2	Hs.97837	3	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
224477_s_at	0.366	6.507	3.645	2.345e-03	0.217	-1.330	NUDT16L1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1	16	4683716	BC006223	84309	16p13.3	Hs.592084	5	cytoplasm
206907_at	-0.342	4.262	-3.643	2.354e-03	0.217	-1.333	TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	19	6482009	NM_003811	8744	19p13.3	Hs.1524	32	cytokine activity tumor necrosis factor receptor binding extracellular space apoptosis immune response signal transduction cell-cell signaling cell proliferation membrane integral to membrane	Cytokine-cytokine receptor interaction
239359_at	-0.354	4.505	-3.642	2.361e-03	0.217	-1.336	MARCH11	membrane-associated ring finger (C3HC4) 11	5	-16120473	AA383208	441061	5p15.1	Hs.662216	2	zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process cytoplasmic vesicle metal ion binding
230724_s_at	-0.462	7.308	-3.641	2.364e-03	0.217	-1.337	C11orf57	chromosome 11 open reading frame 57	11	111450177	BE549742	55216	11q23.1	Hs.195060	6
202920_at	-0.634	9.060	-3.641	2.367e-03	0.217	-1.339	ANK2	ankyrin 2, neuronal	4	113958687, 114190233	BF726212	287	4q25-q27	Hs.620557	39	protein binding cytoplasm cytoskeleton plasma membrane signal transduction basolateral plasma membrane apical plasma membrane M band
1554708_s_at	0.367	4.109	3.640	2.368e-03	0.217	-1.339	C9orf68	chromosome 9 open reading frame 68	9	-4588315	BC034293	55064	9p24.2-p24.1	Hs.179615	5
204117_at	-0.421	8.773	-3.639	2.376e-03	0.217	-1.342	PREP	prolyl endopeptidase	6	-105832198	NM_002726	5550	6q22	Hs.436564	26	serine-type endopeptidase activity cytoplasm proteolysis peptidase activity
232088_x_at	0.540	3.791	3.638	2.379e-03	0.217	-1.343	hCG_2039027	hypothetical LOC100271722	22	-44814452	AL137569	100271722	22q13.31	Hs.528519	3
1557545_s_at	0.541	2.649	3.636	2.389e-03	0.217	-1.347	RNF165	ring finger protein 165	18	42168184	BF529886	494470	18q21.1	Hs.501114	4	protein binding zinc ion binding metal ion binding
204979_s_at	-0.390	11.743	-3.635	2.395e-03	0.217	-1.349	SH3BGR	SH3 domain binding glutamic acid-rich protein	21	39739666, 39745649	NM_007341	6450	21q22.3	Hs.473847	8	SH3/SH2 adaptor activity cytosol protein complex assembly SH3 domain binding
221931_s_at	-0.486	8.078	-3.635	2.396e-03	0.217	-1.350	SEH1L	SEH1-like (S. cerevisiae)	18	12937982	AV701173	81929	18p11.21	Hs.301048	9	kinetochore nucleus nuclear pore organization mitotic metaphase plate congression protein transport Nup107-160 complex Nup107-160 complex mRNA transport attachment of spindle microtubules to kinetochore during mitosis intracellular protein transmembrane transport
206241_at	-0.747	5.551	-3.634	2.398e-03	0.217	-1.350	KPNA5	karyopherin alpha 5 (importin alpha 6)	6	117109059	NM_002269	3841	6q22.1	Hs.182971	46	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
219632_s_at	0.554	5.676	3.634	2.399e-03	0.217	-1.351	TRPV1	transient receptor potential cation channel, subfamily V, member 1	17	-3415489, -3415489, -3415489, -3415489	AF196175	7442	17p13.2	Hs.579217 Hs.655380	107	nucleotide binding ion channel activity calcium channel activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ion transport calcium ion transport cell surface receptor linked signal transduction chemosensory behavior thermoception	Neuroactive ligand-receptor interaction
241827_at	0.495	6.408	3.633	2.403e-03	0.217	-1.352	ZNF615	zinc finger protein 615	19	-57186399	AL577866	284370	19q13.41	Hs.368355	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212586_at	-0.549	9.942	-3.633	2.404e-03	0.217	-1.352	CAST	calpastatin	5	96023696, 96064251, 96104999	AA195244	831	5q15	Hs.436186	60	protein binding calcium-dependent cysteine-type endopeptidase inhibitor activity
200848_at	-0.548	8.701	-3.633	2.405e-03	0.217	-1.353	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	AA479488	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
1554863_s_at	-0.548	7.602	-3.625	2.445e-03	0.219	-1.368	DOK5	docking protein 5	20	52525672	BC008992	55816	20q13.2	Hs.656582	10	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
201387_s_at	1.235	7.216	3.620	2.471e-03	0.220	-1.377	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	4	40953654	NM_004181	7345	4p14	Hs.518731	94	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding intracellular nucleus nucleolus cytoplasm cytoplasm cytosol ubiquitin-dependent protein catabolic process response to stress axon target recognition adult walking behavior peptidase activity omega peptidase activity cell proliferation protein deubiquitination ligase activity axon transport of mitochondrion axon eating behavior cell soma ubiquitin binding neuromuscular process	Parkinson's disease
218507_at	0.388	5.653	3.619	2.477e-03	0.220	-1.379	C7orf68	chromosome 7 open reading frame 68	7	127883119	NM_013332	29923	7q32.1	Hs.710088	9	molecular_function cellular_component response to stress membrane integral to membrane
225007_at	-0.425	7.564	-3.617	2.484e-03	0.220	-1.382	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	AV705516	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
238613_at	-0.505	9.818	-3.614	2.499e-03	0.221	-1.387	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AI475164	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
209780_at	-1.147	9.763	-3.614	2.503e-03	0.221	-1.389	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AL136883	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
226648_at	-0.474	6.811	-3.610	2.521e-03	0.221	-1.395	HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	10	102285630	AI769745	55662	10q24	Hs.500788	30	peptide-aspartate beta-dioxygenase activity iron ion binding protein binding nucleus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
243618_s_at	0.425	8.093	3.610	2.521e-03	0.221	-1.395	ZNF827	zinc finger protein 827	4	-146901337	BF678830	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
217849_s_at	0.330	5.656	3.610	2.521e-03	0.221	-1.395	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	14	-102468468	NM_006035	9578	14q32.3	Hs.654634	9	nucleotide binding magnesium ion binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding cytoplasm cytoskeleton cell-cell junction protein amino acid phosphorylation cytoskeleton organization establishment or maintenance of cell polarity intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding cell leading edge actin cytoskeleton reorganization
233825_s_at	-0.678	7.468	-3.609	2.526e-03	0.221	-1.397	CD99L2	CD99 molecule-like 2	X	-149685466	AU158444	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
243738_at	-0.295	6.025	-3.609	2.527e-03	0.221	-1.397	NMNAT3	nicotinamide nucleotide adenylyltransferase 3	3	-140761722	AW172570	349565	3q23	Hs.208673	6	nucleotide binding magnesium ion binding nicotinamide-nucleotide adenylyltransferase activity nicotinate-nucleotide adenylyltransferase activity ATP binding mitochondrion biosynthetic process NAD biosynthetic process transferase activity nucleotidyltransferase activity pyridine nucleotide biosynthetic process	Nicotinate and nicotinamide metabolism Metabolic pathways
210201_x_at	-0.483	10.934	-3.609	2.528e-03	0.221	-1.398	BIN1	bridging integrator 1	2	-127522077, -127522076	AF001383	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
231045_x_at	-0.332	8.514	-3.608	2.530e-03	0.221	-1.398	C11orf31	chromosome 11 open reading frame 31	11	57265297	H29876	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
219603_s_at	0.452	4.885	3.607	2.536e-03	0.221	-1.400	ZNF226	zinc finger protein 226	19	49361088, 49361088, 49361096, 49361156	NM_015919	7769	19q13.2	Hs.145956	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
206392_s_at	0.577	3.499	3.607	2.538e-03	0.221	-1.401	RARRES1	retinoic acid receptor responder (tazarotene induced) 1	3	-159905133, -159897590	NM_002888	5918	3q25.32	Hs.131269	11	negative regulation of cell proliferation membrane integral to membrane
1558426_x_at	0.365	7.256	3.603	2.557e-03	0.222	-1.408	ORAI2	ORAI calcium release-activated calcium modulator 2	7	101861000	BC016797	80228	7q22.1	Hs.363308	12	membrane integral to membrane
203961_at	0.472	4.351	3.601	2.570e-03	0.223	-1.413	NEBL	nebulette	10	-21108910, -21108910	AL157398	10529	10p12	Hs.5025	15	actin binding structural constituent of muscle regulation of actin filament length
200798_x_at	-0.796	6.800	-3.597	2.593e-03	0.224	-1.420	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	1	-148813658	NM_021960	4170	1q21	Hs.719112	154	cell fate determination protein binding nucleus nucleoplasm cytoplasm mitochondrion mitochondrial outer membrane anti-apoptosis multicellular organismal development protein channel activity membrane integral to membrane cellular homeostasis cell differentiation response to cytokine stimulus regulation of apoptosis protein heterodimerization activity
206685_at	0.304	3.409	3.596	2.593e-03	0.224	-1.421	HCG4	HLA complex group 4	6	-29866787, -1211427, -1013559	NM_018985	54435	6p21.3	Hs.660431	2
1554250_s_at	0.513	4.744	3.595	2.600e-03	0.225	-1.423	TRIM73	tripartite motif-containing 73	7	74862838	BC033812	375593	7q11.23	Hs.632307 Hs.661254	5	protein binding intracellular zinc ion binding metal ion binding
223298_s_at	0.708	10.065	3.591	2.625e-03	0.225	-1.431	NT5C3	5'-nucleotidase, cytosolic III	7	-33020266, -33020266	AF312735	51251	7p14.3	Hs.487933	22	nucleotide binding magnesium ion binding cytoplasm endoplasmic reticulum pyrimidine nucleoside metabolic process 5'-nucleotidase activity 5'-nucleotidase activity 2'-phosphotransferase activity 2'-phosphotransferase activity nucleotide metabolic process hydrolase activity	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
231014_at	0.309	4.971	3.591	2.625e-03	0.225	-1.432	TRIM50	tripartite motif-containing 50	7	-72364470	BG413545	135892	7q11.23	Hs.647053	4	protein binding intracellular cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
201195_s_at	-0.611	6.278	-3.590	2.628e-03	0.225	-1.433	SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	16	-86421129	AB018009	8140	16q24.3	Hs.513797	44	cytoplasm cytosol plasma membrane cellular amino acid metabolic process transport multicellular organismal development nervous system development neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity neutral amino acid transport L-amino acid transport integral to membrane cell differentiation peptide antigen binding
200993_at	-0.385	10.084	-3.590	2.629e-03	0.225	-1.433	IPO7	importin 7	11	9362744	AA939270	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
239582_at	0.278	4.301	3.588	2.637e-03	0.225	-1.436	PML	promyelocytic leukemia	15	72074066, 72074066, 72074066	AW514654	5371	15q22	Hs.526464	208	response to hypoxia DNA binding intracellular insoluble fraction nucleus nucleoplasm nucleolus cytoplasm protein complex assembly induction of apoptosis activation of caspase activity DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest cell cycle arrest transforming growth factor beta receptor signaling pathway common-partner SMAD protein phosphorylation SMAD protein nuclear translocation cell aging zinc ion binding negative regulation of cell proliferation response to UV response to gamma radiation nuclear matrix negative regulation of transcription negative regulation of angiogenesis PML body myeloid cell differentiation negative regulation of cell growth transcription regulator activity PML body organization ubiquitin protein ligase binding nuclear membrane response to cytokine stimulus DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis protein homodimerization activity interspecies interaction between organisms regulation of MHC class I biosynthetic process SMAD binding metal ion binding retinoic acid receptor signaling pathway maintenance of protein location in nucleus	Ubiquitin mediated proteolysis Pathways in cancer Acute myeloid leukemia
222742_s_at	0.390	8.412	3.588	2.641e-03	0.225	-1.437	RABL5	RAB, member RAS oncogene family-like 5	7	-100743368	AW026449	64792	7q22.1	Hs.389104	4	nucleotide binding GTP binding
203122_at	0.367	7.758	3.585	2.653e-03	0.226	-1.441	TTC15	tetratricopeptide repeat domain 15	2	3362452	NM_016030	51112	2p25.3	Hs.252713	4	binding
225911_at	1.023	4.528	3.584	2.663e-03	0.226	-1.445	NPNT	nephronectin	4	107036053	AL138410	255743	4q24	Hs.518921	5	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development membrane cell differentiation
228279_s_at	-0.294	5.243	-3.583	2.664e-03	0.226	-1.445	TNK2	tyrosine kinase, non-receptor, 2	3	-197074632, -197074632	BE676245	10188	3q29	Hs.518513	37	nucleotide binding magnesium ion binding non-membrane spanning protein tyrosine kinase activity GTPase inhibitor activity protein binding ATP binding plasma membrane protein amino acid phosphorylation small GTPase mediated signal transduction transferase activity positive regulation of peptidyl-tyrosine phosphorylation
222470_s_at	-0.670	5.467	-3.582	2.670e-03	0.226	-1.447	UQCC	ubiquinol-cytochrome c reductase complex chaperone	20	-33353794	AA033998	55245	20q11.22	Hs.714359	16	cytoplasmic vesicle
201927_s_at	0.558	4.605	3.582	2.674e-03	0.226	-1.448	PKP4	plakophilin 4	2	159021721	BG292559	8502	2q23-q31	Hs.407580	27	protein binding cell adhesion desmosome
202942_at	0.569	9.610	3.571	2.731e-03	0.230	-1.467	ETFB	electron-transfer-flavoprotein, beta polypeptide	19	-56540220, -56540220	NM_001985	2109	19q13.3	Hs.348531	16	mitochondrion mitochondrial matrix transport electron carrier activity electron transport chain
231727_s_at	0.402	7.053	3.570	2.739e-03	0.230	-1.470	MIF4GD	MIF4G domain containing	17	-70773905	NM_020679	57409	17q25.1	Hs.325631	5	protein binding nucleus cytoplasm regulation of translation RNA metabolic process
201905_s_at	0.583	5.396	3.569	2.746e-03	0.230	-1.472	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF590317	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
209142_s_at	-0.738	10.214	-3.568	2.748e-03	0.230	-1.473	UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	17	-4119260	BC002775	7326	17p13.2 1q42	Hs.714345	12	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
209412_at	-0.464	6.010	-3.566	2.763e-03	0.231	-1.478	TRAPPC10	trafficking protein particle complex 10	21	44256633	U61500	7109	21q22.3	Hs.126221	12	Golgi apparatus sodium ion transport sodium ion transmembrane transporter activity integral to membrane vesicle-mediated transport
219493_at	0.559	4.573	3.566	2.764e-03	0.231	-1.478	SHCBP1	SHC SH2-domain binding protein 1	16	-45171968	NM_024745	79801	16q11.2	Hs.123253	17	protein binding SH2 domain binding
209138_x_at	0.794	4.901	3.564	2.770e-03	0.231	-1.480	IGL@	immunoglobulin lambda locus	22		M87790	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
223478_at	-0.401	7.772	-3.560	2.794e-03	0.231	-1.488	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)	11	-111461079	AF165967	26521	11q23.1-q23.2	Hs.279915	6	protein binding mitochondrion mitochondrial inner membrane presequence translocase complex sensory perception of sound zinc ion binding protein transport membrane mitochondrial intermembrane space protein transporter complex protein import into mitochondrial inner membrane metal ion binding intracellular protein transmembrane transport
223520_s_at	0.362	3.710	3.560	2.795e-03	0.231	-1.488	KIF13A	kinesin family member 13A	6	-17871902, -17868563	AY014403	63971	6p23	Hs.189915	14	nucleotide binding microtubule motor activity protein binding ATP binding microtubule microtubule-based movement protein transport
217599_s_at	-0.872	5.959	-3.559	2.799e-03	0.231	-1.489	MDFIC	MyoD family inhibitor domain containing	7	114349444	BE910600	29969	7q31.1-q31.2	Hs.427236	7	nucleus nucleolus cytoplasm activation of JUN kinase activity regulation of Wnt receptor signaling pathway cyclin binding Tat protein binding interspecies interaction between organisms regulation of transcription positive regulation of viral transcription
1558956_s_at	0.396	6.603	3.559	2.803e-03	0.231	-1.490	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)	3	-161457481	AI473255	57560	3q25.33	Hs.478095	7	cytoplasm
213327_s_at	-0.421	6.620	-3.558	2.806e-03	0.231	-1.492	USP12	ubiquitin specific peptidase 12	13	-26540437	AI820101	219333	13q12.13	Hs.42400	6	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding cellular_component protein modification process ubiquitin-dependent protein catabolic process peptidase activity protein deubiquitination
227127_at	-0.366	6.114	-3.558	2.810e-03	0.231	-1.493	TMEM110	transmembrane protein 110	3	-52848937	BF222855	375346	3p21.1	Hs.705605	2	molecular_function cellular_component biological_process membrane integral to membrane
1553961_s_at	0.556	6.769	3.557	2.813e-03	0.231	-1.494	SNX21	sorting nexin family member 21	20	43895876	CA447177	90203	20q13.12	Hs.472854	8	protein binding cell communication protein transport phosphoinositide binding
201397_at	0.296	6.069	3.555	2.822e-03	0.231	-1.497	PHGDH	phosphoglycerate dehydrogenase	1	120055941	NM_006623	26227	1p12	Hs.487296	18	phosphoglycerate dehydrogenase activity L-serine biosynthetic process brain development cellular amino acid biosynthetic process electron carrier activity oxidoreductase activity cofactor binding NAD or NADH binding oxidation reduction	Glycine, serine and threonine metabolism Metabolic pathways
218428_s_at	0.526	8.206	3.555	2.824e-03	0.231	-1.497	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	NM_016316	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
226109_at	0.528	6.442	3.554	2.830e-03	0.231	-1.499	C21orf91	chromosome 21 open reading frame 91	21	-18083154	AK023825	54149	21q21.1	Hs.293811	8
210153_s_at	0.449	7.460	3.553	2.839e-03	0.231	-1.502	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	18	46659432	M55905	4200	18q21 6p25-p24	Hs.233119	24	malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide
232696_at	0.485	3.719	3.548	2.865e-03	0.233	-1.510	LOC648556	uncharacterized gastric protein ZA43P	16		AI394334	648556		Hs.203594
238841_at	0.390	5.301	3.548	2.868e-03	0.233	-1.511	PTPDC1	protein tyrosine phosphatase domain containing 1	9	95832896, 95886566	AA651920	138639	9q22.32	Hs.437943	2	protein tyrosine phosphatase activity protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
219390_at	0.426	4.786	3.547	2.872e-03	0.233	-1.513	FKBP14	FK506 binding protein 14, 22 kDa	7	-30019408	NM_017946	55033	7p14.3	Hs.571333	7	peptidyl-prolyl cis-trans isomerase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen protein folding isomerase activity
204783_at	-1.499	7.532	-3.545	2.885e-03	0.233	-1.517	MLF1	myeloid leukemia factor 1	3	159771646	AI911434	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
218954_s_at	-0.538	6.227	-3.544	2.888e-03	0.233	-1.518	BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	8	-37820560	AF298153	55290	8p11.23	Hs.709301	11	protein binding nucleus transcription factor complex transcription initiation regulation of transcription, DNA-dependent zinc ion binding transcription regulator activity metal ion binding
238454_at	0.795	4.467	3.544	2.889e-03	0.233	-1.518	ZNF540	zinc finger protein 540	19	42734147	AA013398	163255	19q13.12	Hs.121283	5	DNA binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218910_at	0.294	5.975	3.543	2.894e-03	0.233	-1.519	ANO10	anoctamin 10	3	-43382821	NM_018075	55129	3p22.1	Hs.656657	3	ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex
217930_s_at	0.388	7.280	3.541	2.905e-03	0.233	-1.523	TOLLIP	toll interacting protein	11	-1252176	NM_019009	54472	11p15.5	Hs.368527	24	signal transducer activity Toll binding protein binding cytoplasm inflammatory response immune response intracellular signaling cascade cell-cell signaling phosphorylation interleukin-18 receptor complex leukocyte activation interleukin-1 receptor complex	Toll-like receptor signaling pathway
202038_at	-0.486	8.304	-3.540	2.915e-03	0.233	-1.526	UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)	11	117735511	NM_004788	9354	11q23.3	Hs.602967 Hs.75275	12	ubiquitin ligase complex protein polyubiquitination protein binding cytoplasm ubiquitin-dependent protein catabolic process ubiquitin-ubiquitin ligase activity	Ubiquitin mediated proteolysis
1553177_at	-1.172	6.108	-3.540	2.916e-03	0.233	-1.526	SH2D1B	SH2 domain containing 1B	1	-160631679	BC022407	117157	1q23.3	Hs.350581	10	molecular_function protein binding cellular_component biological_process	Natural killer cell mediated cytotoxicity
233977_at	0.430	5.994	3.539	2.917e-03	0.233	-1.527	KIAA1772	KIAA1772	18	17076200	AB051559	80000	18q11.1-q11.2	Hs.149020	4	membrane integral to membrane
228831_s_at	0.456	6.001	3.536	2.937e-03	0.234	-1.533	GNG7	guanine nucleotide binding protein (G protein), gamma 7	19	-2462217	AL039870	2788	19p13.3	Hs.515544	12	behavioral fear response signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction receptor guanylyl cyclase signaling pathway locomotory behavior regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
230623_x_at	-0.442	7.821	-3.532	2.961e-03	0.236	-1.540	USP28	ubiquitin specific peptidase 28	11	-113173806	AI609285	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
213957_s_at	-0.354	5.306	-3.529	2.979e-03	0.237	-1.545	CEP350	centrosomal protein 350kDa	1	178190530	AA635523	9857	1p36.13-q41	Hs.413045	17	nucleus centrosome spindle
235328_at	0.321	5.158	3.529	2.983e-03	0.237	-1.547	PLXNC1	plexin C1	12	93066629	AA521145	10154	12q23.3	Hs.584845	10	receptor activity receptor binding intracellular plasma membrane cell adhesion signal transduction multicellular organismal development integral to membrane	Axon guidance
202065_s_at	-0.259	5.816	-3.526	2.996e-03	0.237	-1.551	PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	11	69794470, 69794470	BG033593	8500	11q13.3	Hs.530749	17	signal transducer activity protein binding cytoplasm cell-matrix adhesion signal transduction
226876_at	0.543	7.080	3.526	2.996e-03	0.237	-1.551	FAM101B	family with sequence similarity 101, member B	17	-289998	AI961778	359845	17p13	Hs.345588 Hs.596411 Hs.719324	4
201694_s_at	-1.935	7.003	-3.526	2.997e-03	0.237	-1.551	EGR1	early growth response 1	5	137829079	NM_001964	1958	5q31.1	Hs.326035 Hs.708393	174	negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent learning or memory zinc ion binding transcription activator activity T cell differentiation positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding	Prion diseases
1569566_at	-0.926	4.803	-3.526	3.001e-03	0.237	-1.552	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	BC028196	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
229088_at	0.536	4.195	3.525	3.007e-03	0.237	-1.554	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	6	132170848	BF591996	5167	6q22-q23	Hs.527295	107	nucleic acid binding phosphodiesterase I activity nucleotide diphosphatase activity nucleotide diphosphatase activity scavenger receptor activity insulin receptor binding protein binding ATP binding extracellular space plasma membrane plasma membrane generation of precursor metabolites and energy phosphate metabolic process immune response metabolic process nucleoside triphosphate catabolic process cell surface integral to membrane basolateral plasma membrane hydrolase activity polysaccharide binding negative regulation of cell growth regulation of bone mineralization inorganic diphosphate transport cellular phosphate ion homeostasis sequestering of triglyceride biomineral formation negative regulation of protein amino acid autophosphorylation cellular response to insulin stimulus protein homodimerization activity negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process negative regulation of glucose import negative regulation of insulin receptor signaling pathway metal ion binding nucleoside-triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process 3'-phosphoadenosine 5'-phosphosulfate binding	Purine metabolism Starch and sucrose metabolism Riboflavin metabolism Nicotinate and nicotinamide metabolism Pantothenate and CoA biosynthesis Metabolic pathways
218857_s_at	0.510	6.547	3.524	3.014e-03	0.237	-1.556	ASRGL1	asparaginase like 1	11	61861349	NM_025080	80150	11q12.3	Hs.535326	9	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity cytoplasm hydrolase activity asparagine catabolic process via L-aspartate	Alanine, aspartate and glutamate metabolism Cyanoamino acid metabolism Nitrogen metabolism Metabolic pathways
218695_at	0.596	6.821	3.521	3.027e-03	0.237	-1.560	EXOSC4	exosome component 4	8	145205509	NM_019037	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
221959_at	-0.364	5.923	-3.521	3.033e-03	0.237	-1.562	FAM110B	family with sequence similarity 110, member B	8	59069666	BE672313	90362	8q12.1	Hs.154652	7	cytoplasm mitochondrion centrosome
213328_at	0.384	5.439	3.520	3.036e-03	0.237	-1.563	NEK1	NIMA (never in mitosis gene a)-related kinase 1	4	-170551003	AI936517	4750	4q33	Hs.481181	11	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division
203138_at	-0.538	8.667	-3.520	3.038e-03	0.237	-1.563	HAT1	histone acetyltransferase 1	2	172487180	NM_003642	8520	2q31.2-q33.1	Hs.632532	14	histone acetyltransferase activity protein binding nucleus cytoplasm DNA packaging chromatin silencing at telomere internal protein amino acid acetylation acyltransferase activity chromatin modification histone acetylation transferase activity
204058_at	0.617	9.331	3.519	3.041e-03	0.237	-1.564	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	6	-83976828	AL049699	4199	6q12	Hs.21160	24	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway
212998_x_at	0.899	5.689	3.516	3.061e-03	0.238	-1.570	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	AI583173	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
229176_at	-0.476	5.700	-3.509	3.109e-03	0.241	-1.584	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	AI672354	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
224566_at	-0.868	10.652	-3.507	3.122e-03	0.241	-1.588	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AI042152	283131	11q13.1	Hs.523789 Hs.648467	6
225191_at	0.432	7.279	3.506	3.124e-03	0.241	-1.588	CIRBP	cold inducible RNA binding protein	19	1220266, 1220266	AL565767	1153	19p13.3	Hs.634522 Hs.664127	17	nucleotide binding RNA binding protein binding nucleus nucleoplasm response to cold
208767_s_at	-1.204	9.437	-3.503	3.142e-03	0.241	-1.593	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	AW149681	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
225419_at	-0.252	6.913	-3.502	3.151e-03	0.241	-1.596	C7orf11	chromosome 7 open reading frame 11	7	-40138866	AI869704	136647	7p14.1	Hs.654989	9	nucleus
1557057_a_at	0.262	1.972	3.501	3.156e-03	0.241	-1.597	C5orf47	chromosome 5 open reading frame 47	5	173348767	AL039665	133491	5q35.2	Hs.131469	1
238843_at	-0.524	6.833	-3.501	3.157e-03	0.241	-1.598	NPHP1	nephronophthisis 1 (juvenile)	2	-110238202	BF216535	4867	2q13	Hs.280388	36	structural molecule activity protein binding adherens junction signal transduction excretion visual behavior membrane cell-cell adhesion actin cytoskeleton organization cell junction
206724_at	0.339	2.794	3.501	3.159e-03	0.241	-1.598	CBX4	chromobox homolog 4 (Pc class homolog, Drosophila)	17	-75421549	NM_003655	8535	17q25.3	Hs.714363	25	chromatin chromatin binding transcription corepressor activity nucleus chromatin assembly or disassembly anti-apoptosis negative regulation of transcription chromatin modification enzyme binding modification-dependent protein catabolic process
201297_s_at	-0.595	5.545	-3.501	3.161e-03	0.241	-1.599	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	2	-74236718	AK023321	55233	2p13.1	Hs.196437	12	protein binding zinc ion binding metal ion binding
228863_at	0.556	4.329	3.500	3.164e-03	0.241	-1.600	PCDH17	protocadherin 17	13	57103789	N69091	27253	13q21.1	Hs.106511	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
201471_s_at	-0.368	9.615	-3.498	3.179e-03	0.241	-1.604	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	NM_003900	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
213552_at	0.453	4.640	3.497	3.186e-03	0.241	-1.606	GLCE	glucuronic acid epimerase	15	67240026	W87398	26035	15q23	Hs.183006	9	Golgi apparatus heparan sulfate proteoglycan biosynthetic process membrane integral to membrane isomerase activity heparin biosynthetic process UDP-glucuronate 5'-epimerase activity	Heparan sulfate biosynthesis Metabolic pathways
202393_s_at	-0.854	9.258	-3.497	3.187e-03	0.241	-1.606	KLF10	Kruppel-like factor 10	8	-103730182, -103730182	NM_005655	7071	8q22.2	Hs.435001	26	negative regulation of transcription from RNA polymerase II promoter skeletal system development transcription factor activity protein binding intracellular nucleus transforming growth factor beta receptor signaling pathway cell-cell signaling zinc ion binding negative regulation of cell proliferation regulation of transcription metal ion binding
225962_at	0.433	5.216	3.496	3.192e-03	0.241	-1.608	ZNRF1	zinc and ring finger 1	16	73590415	AI199541	84937	16q23.1	Hs.427284	11	protein binding lysosome endosome zinc ion binding membrane ligase activity modification-dependent protein catabolic process cell junction cytoplasmic vesicle synapse metal ion binding
227339_at	-0.320	5.458	-3.495	3.196e-03	0.241	-1.609	RGMB	RGM domain family, member B	5	98132898	BE206621	285704	5q15	Hs.526902	5	ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane
219396_s_at	0.287	6.138	3.495	3.200e-03	0.241	-1.610	NEIL1	nei endonuclease VIII-like 1 (E. coli)	15	73426383	NM_024608	79661	15q24.2	Hs.512732	35	damaged DNA binding DNA-(apurinic or apyrimidinic site) lyase activity nucleus cytoplasm base-excision repair nucleotide-excision repair response to DNA damage stimulus response to oxidative stress protein C-terminus binding metabolic process zinc ion binding lyase activity DNA N-glycosylase activity negative regulation of nuclease activity	Base excision repair
238975_at	0.419	4.701	3.494	3.204e-03	0.241	-1.611	MMAB	methylmalonic aciduria (cobalamin deficiency) cblB type	12	-108475903	AI671390	326625	12q24	Hs.12106	16	nucleotide binding ATP binding mitochondrion cob(I)yrinic acid a,c-diamide adenosyltransferase activity cobalamin biosynthetic process transferase activity	Porphyrin and chlorophyll metabolism Metabolic pathways
213906_at	0.411	4.429	3.492	3.220e-03	0.241	-1.615	MYBL1	v-myb myeloblastosis viral oncogene homolog (avian)-like 1	8	-67636963	AW592266	4603	8q22	Hs.445898	8	DNA binding nucleus nucleolus regulation of transcription, DNA-dependent transcription activator activity
1559190_s_at	0.530	5.767	3.488	3.241e-03	0.242	-1.621	RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	19	-60247503, -60247503	AL833150	112724	19q13.42	Hs.327631	9	binding oxidoreductase activity oxidation reduction
220233_at	0.378	5.404	3.485	3.267e-03	0.243	-1.628	FBXO17	F-box protein 17	19	-44123881, -44123881	NM_024907	115290	19q13.2	Hs.531770	7	protein binding modification-dependent protein catabolic process protein catabolic process
212337_at	-0.355	6.380	-3.484	3.271e-03	0.243	-1.630	TUG1	taurine upregulated 1 (non-protein coding)	22	29695633	AI687738	55000	22q12.2	Hs.554829	7
205471_s_at	0.573	4.605	3.483	3.277e-03	0.243	-1.631	DACH1	dachshund homolog 1 (Drosophila)	13	-70910098	AW772082	1602	13q22	Hs.129452	24	nucleotide binding transcription factor activity protein binding nucleus transcription factor complex cytoplasm multicellular organismal development regulation of transcription
213012_at	-0.955	7.748	-3.481	3.290e-03	0.243	-1.635	NEDD4	neural precursor cell expressed, developmentally down-regulated 4	15	-53906413, -53906413	D42055	4734	15q	Hs.1565	79	ubiquitin ligase complex chromatin ubiquitin-protein ligase activity intracellular membrane fraction cytoplasm cytosol plasma membrane cell cortex protein modification process protein targeting to lysosome pathogenesis negative regulation of sodium ion transport negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage positive regulation of phosphoinositide 3-kinase cascade apicolateral plasma membrane ligase activity acid-amino acid ligase activity transmission of virus sodium channel inhibitor activity protein domain specific binding modification-dependent protein catabolic process neuron projection development receptor internalization beta-2 adrenergic receptor binding receptor catabolic process cellular response to UV protein ubiquitination during ubiquitin-dependent protein catabolic process glucocorticoid receptor signaling pathway ubiquitin binding ubiquitin binding positive regulation of protein catabolic process positive regulation of nucleocytoplasmic transport perinuclear region of cytoplasm phosphoserine binding phosphothreonine binding progesterone receptor signaling pathway response to calcium ion RNA polymerase binding proline-rich region binding	Ubiquitin mediated proteolysis Endocytosis
217924_at	-0.416	6.187	-3.480	3.295e-03	0.243	-1.636	C6orf106	chromosome 6 open reading frame 106	6	-34663047	AL523965	64771	6p21.31	Hs.643498	10
209637_s_at	0.369	4.026	3.480	3.298e-03	0.243	-1.637	RGS12	regulator of G-protein signaling 12	4	3285671, 3285671, 3341521	AA887475	6002	4p16.3	Hs.527061	14	condensed nuclear chromosome receptor signaling protein activity GTPase activator activity protein binding nucleus regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction
221808_at	-0.435	7.489	-3.479	3.305e-03	0.243	-1.639	RAB9A	RAB9A, member RAS oncogene family	X	13617261	NM_004251	9367	Xp22.2	Hs.495704	24	Golgi membrane nucleotide binding GTPase activity protein binding GTP binding lysosome late endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport
227285_at	-1.414	6.543	-3.478	3.309e-03	0.243	-1.640	C1orf51	chromosome 1 open reading frame 51	1	148521852	AW080835	148523	1q21.2	Hs.54680	4
226770_at	0.402	4.535	3.477	3.317e-03	0.243	-1.642	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	1	113734997, 113734997	AI692181	260425	1p12-p11.2	Hs.486189	13	nucleotide binding protein binding ATP binding nucleus plasma membrane tight junction cell junction interspecies interaction between organisms	Tight junction
228501_at	0.633	5.727	3.477	3.321e-03	0.243	-1.643	GALNTL2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	3	16191187	BF055343	117248	3p25.1	Hs.411308	10	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups transport vesicle manganese ion binding	O-Glycan biosynthesis Metabolic pathways
1560128_x_at	0.361	5.796	3.476	3.324e-03	0.243	-1.644	C5orf56	chromosome 5 open reading frame 56	5	131774571	AL713721	441108	5q31.1	Hs.658288	1
200941_at	-0.463	7.861	-3.476	3.326e-03	0.243	-1.645	HSBP1	heat shock factor binding protein 1	16	82399093	AK026575	3281	16q23.3	Hs.250899 Hs.705549	8	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus
213737_x_at	0.330	8.885	3.476	3.328e-03	0.243	-1.645	GOLGA9P	golgi autoantigen, golgin subfamily a, 9 pseudogene	15	20806682	AI620911	283796	15q11.2	Hs.375441	2
212307_s_at	-0.375	7.187	-3.475	3.334e-03	0.243	-1.647	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	70669657	BF001665	8473	Xq13	Hs.405410	47	protein binding nucleus cytoplasm cytosol protein amino acid O-linked glycosylation signal transduction response to nutrient acetylglucosaminyltransferase activity transferase activity, transferring glycosyl groups MLL5-L complex	O-Glycan biosynthesis Metabolic pathways
230669_at	0.469	5.933	3.473	3.347e-03	0.244	-1.650	RASA2	RAS p21 protein activator 2	3	142688615	W38444	5922	3q22-q23	Hs.655941	7	Ras GTPase activator activity intracellular cytoplasm intracellular signaling cascade zinc ion binding metal ion binding perinuclear region of cytoplasm regulation of small GTPase mediated signal transduction	MAPK signaling pathway
226086_at	0.624	4.715	3.472	3.354e-03	0.244	-1.652	SYT13	synaptotagmin XIII	11	-45218428	AB037848	57586	11p12-p11	Hs.436643	12	integral to plasma membrane membrane vesicle-mediated transport transport vesicle
217811_at	-0.357	8.433	-3.470	3.364e-03	0.245	-1.655	SELT	selenoprotein T	3	151803755	NM_016275	51714	3q25.1	Hs.369052	9	selenocysteine incorporation selenium binding cell redox homeostasis
221889_at	0.327	4.909	3.469	3.377e-03	0.245	-1.658	KCTD13	potassium channel tetramerisation domain containing 13	16	-29825161	AW026481	253980	16p11.2	Hs.534590	9	voltage-gated potassium channel activity nucleus DNA replication potassium ion transport voltage-gated potassium channel complex membrane identical protein binding
202236_s_at	-0.787	8.193	-3.468	3.379e-03	0.245	-1.659	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	NM_003051	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
224638_at	0.277	5.462	3.467	3.391e-03	0.246	-1.662	UNQ1887	signal peptide peptidase 3	12	-119685417	AI338356	121665	12q24.31	Hs.507087 Hs.683964	12	aspartic-type endopeptidase activity peptidase activity membrane integral to membrane
37145_at	0.527	4.501	3.465	3.403e-03	0.246	-1.665	GNLY	granulysin	2	85774924	M85276	10578	2p11.2	Hs.105806	36	extracellular region extracellular space xenobiotic metabolic process cellular defense response defense response to bacterium defense response to fungus
217992_s_at	0.311	5.492	3.464	3.406e-03	0.246	-1.666	EFHD2	EF-hand domain family, member D2	1	15608977	NM_024329	79180	1p36.21	Hs.465374	8	calcium ion binding protein binding
1558080_s_at	0.387	3.350	3.462	3.424e-03	0.247	-1.671	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	13	95127402	BG913589	5611	13q32.1	Hs.59214	19	protein kinase inhibitor activity binding cytoplasm endoplasmic reticulum response to unfolded protein response to virus heat shock protein binding
226582_at	0.487	5.377	3.460	3.435e-03	0.247	-1.674	LOC400043	hypothetical LOC400043	12	52806121	AL520272	400043	12q13.13	Hs.19193	2
202363_at	0.949	6.012	3.460	3.438e-03	0.247	-1.674	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	5	-136338885	AF231124	6695	5q31	Hs.643338	15	calcium ion binding extracellular region proteinaceous extracellular matrix cell motion cell adhesion signal transduction multicellular organismal development nervous system development cell proliferation
206256_at	-0.269	4.596	-3.458	3.452e-03	0.247	-1.678	CPN1	carboxypeptidase N, polypeptide 1	10	-101792054	NM_001308	1369	10q24.2	Hs.2246	16	metallocarboxypeptidase activity extracellular region extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
200850_s_at	-0.569	8.902	-3.457	3.462e-03	0.247	-1.681	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	NM_006621	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
222186_at	0.300	5.016	3.456	3.463e-03	0.247	-1.681	ZFAND6	zinc finger, AN1-type domain 6	15	78139075	AL109684	54469	15q25.1	Hs.719106	8	molecular_function DNA binding protein binding cellular_component signal transduction biological_process zinc ion binding metal ion binding
234996_at	0.351	2.831	3.456	3.468e-03	0.247	-1.682	CALCRL	calcitonin receptor-like	2	-187916093	AI478743	10203	2q32.1	Hs.470882	56	calcitonin receptor activity plasma membrane integral to plasma membrane G-protein signaling, coupled to cyclic nucleotide second messenger	Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
225819_at	-0.473	5.926	-3.455	3.470e-03	0.247	-1.683	TBRG1	transforming growth factor beta regulator 1	11	123997951	AA576946	84897	11q24.2	Hs.436410	11	DNA binding protein binding nucleus DNA replication cell cycle cell cycle arrest negative regulation of cell proliferation nucleolus to nucleoplasm transport protein stabilization
227474_at	0.818	5.040	3.454	3.477e-03	0.247	-1.685	LOC654433	hypothetical LOC654433	2	113710316	AY007128	654433	2q13	Hs.656660	4
1552791_a_at	-1.322	9.065	-3.451	3.498e-03	0.248	-1.690	TRDN	triadin	6	-123579181	NM_006073	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
209982_s_at	0.314	4.303	3.451	3.500e-03	0.248	-1.691	NRXN2	neurexin 2	11	-64130221, -64130221	AA608820	9379	11q13	Hs.372938	16	calcium ion binding protein binding cell adhesion membrane integral to membrane	Cell adhesion molecules (CAMs)
1565685_at	-0.231	2.573	-3.449	3.516e-03	0.248	-1.695	LOC400940	hypothetical LOC400940	2	6039560	AA774300	400940	2p25.2	Hs.378814	2
227198_at	1.654	4.681	3.447	3.528e-03	0.249	-1.698	AFF3	AF4/FMR2 family, member 3	2	-99530147, -99530147	AW085505	3899	2q11.2-q12	Hs.444414	16	DNA binding nucleus multicellular organismal development regulation of transcription
206818_s_at	0.260	4.704	3.447	3.530e-03	0.249	-1.698	CNNM2	cyclin M2	10	104668103, 104668103	NM_017649	54805	10q24.32	Hs.657970 Hs.719266	3	ion transport membrane integral to membrane
224444_s_at	0.582	5.346	3.446	3.541e-03	0.249	-1.701	C1orf97	chromosome 1 open reading frame 97	1	209622719	BC005997	84791	1q32.3	Hs.523932	4
1556351_at	-0.863	3.388	-3.445	3.544e-03	0.249	-1.702	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	5	-45295108	BM682352	348980	5p12	Hs.650434	17	nucleotide binding voltage-gated ion channel activity voltage-gated potassium channel activity sodium channel activity protein binding ion transport potassium ion transport sodium ion transport membrane integral to membrane axon dendrite cAMP binding potassium ion binding sodium ion binding apical protein localization
202919_at	-0.438	8.679	-3.443	3.561e-03	0.249	-1.706	MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	2	198088564, 198089015	NM_015387	25843	2q33.1	Hs.645458	13	protein binding cytoplasm Golgi apparatus transport zinc ion binding membrane metal ion binding perinuclear region of cytoplasm
1564063_a_at	-0.302	5.207	-3.443	3.562e-03	0.249	-1.706	ATP11B	ATPase, class VI, type 11B	3	183993984	AK093727	23200	3q27	Hs.478429	8	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding nuclear inner membrane ATP biosynthetic process ion transport metabolic process ion transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport aminophospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
235554_x_at	-0.556	4.814	-3.443	3.562e-03	0.249	-1.706	PACRGL	PARK2 co-regulated-like	4	20311133	BE048198	133015	4p15.31	Hs.479298	5	binding
211194_s_at	-0.429	4.551	-3.440	3.580e-03	0.250	-1.711	TP63	tumor protein p63	3	190831909, 190831909, 190990142, 190990142	AB010153	8626	3q28	Hs.137569	238	response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization
211221_at	-0.344	4.365	-3.439	3.586e-03	0.250	-1.712	TADA3L	transcriptional adaptor 3 (NGG1 homolog, yeast)-like	3	-9799811, -9796653	AL117487	10474	3p25.3	Hs.386390	29	transcription factor activity transcription coactivator activity histone acetyltransferase activity protein binding intracellular nucleus regulation of transcription from RNA polymerase II promoter STAGA complex transcription factor TFTC complex histone H3 acetylation regulation of transcription
210246_s_at	0.477	5.357	3.438	3.595e-03	0.250	-1.715	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	11	-17371007	AF087138	6833	11p15.1	Hs.54470	111	nucleotide binding receptor activity ATP binding plasma membrane carbohydrate metabolic process transport potassium ion transport sulfonylurea receptor activity potassium ion transmembrane transporter activity integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters Type II diabetes mellitus
209340_at	-0.655	8.112	-3.438	3.599e-03	0.250	-1.716	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	1	160797919	S73498	6675	1q23.3	Hs.492859	10	UDP-N-acetylglucosamine diphosphorylase activity nucleus nucleolus cytoplasm UDP-N-acetylglucosamine biosynthetic process metabolic process transferase activity nucleotidyltransferase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
221412_at	0.350	4.247	3.438	3.599e-03	0.250	-1.716	VN1R1	vomeronasal 1 receptor 1	19	-62658353	NM_020633	57191	19q13.4	Hs.388810 Hs.677423	9	receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane pheromone receptor activity response to pheromone
222479_s_at	-0.391	8.021	-3.437	3.605e-03	0.250	-1.717	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	3	-32542470	AK001081	51143	3p22.3	Hs.529495	11	nucleotide binding motor activity ATP binding microtubule dynein complex
1560238_at	0.778	4.247	3.437	3.606e-03	0.250	-1.717	LOC100127980	hypothetical protein LOC100127980	19		BM926839	100127980	19q13.12	Hs.595153	1
224580_at	0.381	4.144	3.432	3.643e-03	0.252	-1.727	SLC38A1	solute carrier family 38, member 1	12	-44863107	BF515894	81539	12q13.11	Hs.694701	11	sodium:amino acid symporter activity membrane fraction plasma membrane ion transport sodium ion transport glutamine transport L-glutamine transmembrane transporter activity symporter activity integral to membrane axon sodium ion binding
225547_at	-0.586	10.993	-3.432	3.645e-03	0.252	-1.727	SNHG6	small nucleolar RNA host gene 6 (non-protein coding)	8	-67996718	BG169443	641638	8q13	Hs.372680	1
223636_at	0.586	4.534	3.431	3.650e-03	0.252	-1.728	ZMYND12	zinc finger, MYND-type containing 12	1	-42668589	AL136858	84217	1p34.2	Hs.294009	5	binding intracellular zinc ion binding metal ion binding
1567014_s_at	-0.473	5.957	-3.429	3.665e-03	0.252	-1.732	NFE2L2	nuclear factor (erythroid-derived 2)-like 2	2	-177803279, -177803278	AF323119	4780	2q31	Hs.715540	141	transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity
224609_at	0.394	7.341	3.429	3.666e-03	0.252	-1.732	SLC44A2	solute carrier family 44, member 2	19	10574120, 10597170	AI264216	57153	19p13.1	Hs.534560	13	signal transducer activity transport choline transmembrane transporter activity choline transport membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
208690_s_at	0.795	10.641	3.428	3.673e-03	0.252	-1.734	PDLIM1	PDZ and LIM domain 1	10	-96987319	BC000915	9124	10q22-q26.3	Hs.368525	19	transcription coactivator activity protein binding transcription factor complex cytoplasm cytoskeleton response to oxidative stress zinc ion binding regulation of transcription metal ion binding
203706_s_at	-0.898	7.914	-3.428	3.675e-03	0.252	-1.735	FZD7	frizzled homolog 7 (Drosophila)	2	202607554	NM_003507	8324	2q33	Hs.173859	23	non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway multicellular organismal development integral to membrane Wnt receptor signaling pathway Wnt receptor activity	Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma
212543_at	0.439	4.207	3.427	3.678e-03	0.252	-1.735	AIM1	absent in melanoma 1	6	107066422	U83115	202	6q21	Hs.643590 Hs.717199	12	molecular_function sugar binding cellular_component biological_process
58696_at	0.402	7.082	3.426	3.684e-03	0.252	-1.737	EXOSC4	exosome component 4	8	145205509	AL039469	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
1560741_at	0.770	7.458	3.426	3.685e-03	0.252	-1.737	SNRPN	small nuclear ribonucleoprotein polypeptide N	15	22619886, 22652790, 22751227	AL832250	6638	15q11.2	Hs.555970 Hs.564847 Hs.578619 Hs.585703 Hs.592473 Hs.621316 Hs.632166	47	RNA binding nucleus spliceosomal complex RNA splicing small nuclear ribonucleoprotein complex identical protein binding
206142_at	0.475	2.842	3.421	3.724e-03	0.254	-1.746	ZNF135	zinc finger protein 135	19	63262423	NM_003436	7694	19q13.4	Hs.85863	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
216733_s_at	-1.314	8.037	-3.421	3.725e-03	0.254	-1.747	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	X86401	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
223092_at	-0.549	10.131	-3.420	3.733e-03	0.254	-1.748	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	AA854943	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
229500_at	-0.500	4.475	-3.419	3.739e-03	0.254	-1.750	SLC30A9	solute carrier family 30 (zinc transporter), member 9	4	41687279	AI609256	10463	4p13-p12	Hs.479634	6	nucleotide binding transcription factor activity nucleus cytoskeleton cation transport zinc ion transport biological_process zinc ion binding cation transmembrane transporter activity membrane integral to membrane regulation of transcription
204160_s_at	-0.644	7.255	-3.417	3.757e-03	0.255	-1.754	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)	6	46205659	AW194947	22875	6p21.1	Hs.643497	4	metabolic process membrane integral to membrane hydrolase activity
226607_at	-0.846	8.310	-3.416	3.763e-03	0.255	-1.756	C20orf194	chromosome 20 open reading frame 194	20	-3177947	AI498144	25943	20p13	Hs.516853	7
202811_at	-0.381	8.074	-3.412	3.798e-03	0.256	-1.764	STAMBP	STAM binding protein	2	73909593, 73909634, 73909654	NM_006463	10617	2p13.1	Hs.469018 Hs.657598	28	ubiquitin thiolesterase activity protein binding nucleus cytoplasm early endosome anti-apoptosis JAK-STAT cascade peptidase activity metallopeptidase activity zinc ion binding positive regulation of cell proliferation membrane modification-dependent protein catabolic process metal ion binding	Endocytosis
202931_x_at	-0.448	10.850	-3.411	3.806e-03	0.256	-1.766	BIN1	bridging integrator 1	2	-127522077, -127522076	NM_004305	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
201939_at	0.673	5.403	3.410	3.807e-03	0.256	-1.766	PLK2	polo-like kinase 2 (Drosophila)	5	-57785566	NM_006622	10769	5q12.1-q13.2	Hs.398157 Hs.658132	20	nucleotide binding mitotic cell cycle protein serine/threonine kinase activity signal transducer activity protein binding ATP binding protein amino acid phosphorylation transferase activity polo kinase kinase activity positive regulation of I-kappaB kinase/NF-kappaB cascade
220709_at	0.754	5.270	3.410	3.812e-03	0.256	-1.767	ZNF556	zinc finger protein 556	19	2818332	NM_024967	80032	19p13.3	Hs.287433	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207379_at	-0.256	4.444	-3.410	3.815e-03	0.256	-1.768	EDIL3	EGF-like repeats and discoidin I-like domains 3	5	-83273881	NM_005711	10085	5q14	Hs.482730	6	integrin binding calcium ion binding protein binding extracellular region cell adhesion multicellular organismal development positive regulation of cell-substrate adhesion
229958_at	0.565	6.777	3.403	3.863e-03	0.256	-1.779	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	8	1699276	W93695	2055	8p23	Hs.127675	15	age-dependent response to oxidative stress endoplasmic reticulum ER-Golgi intermediate compartment phospholipid metabolic process lipid transport mitochondrial membrane organization lysosome organization nervous system development adult walking behavior cholesterol metabolic process associative learning regulation of cell size lipid biosynthetic process membrane integral to membrane spinal cord motor neuron differentiation social behavior negative regulation of apoptosis cellular protein catabolic process cellular macromolecule catabolic process photoreceptor cell maintenance negative regulation of proteolysis ceramide biosynthetic process musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate uptake during transmission of nerve impulse retina development in camera-type eye neurofilament cytoskeleton organization
211466_at	0.326	3.931	3.403	3.864e-03	0.256	-1.779	NFIB	nuclear factor I/B	9	-14071846	U70862	4781	9p24.1	Hs.644095	13	transcription factor activity intracellular nucleus nucleolus DNA replication regulation of transcription, DNA-dependent
235212_at	-0.294	3.275	-3.403	3.870e-03	0.256	-1.781	C14orf102	chromosome 14 open reading frame 102	14	-89814150	AA346979	55051	14q32.11	Hs.528131	4	protein binding
224870_at	0.550	9.168	3.403	3.870e-03	0.256	-1.781	KIAA0114	KIAA0114	4	53273377	BG255416	57291	4q12	Hs.17719	4
204186_s_at	-0.572	7.957	-3.402	3.873e-03	0.256	-1.782	PPID	peptidylprolyl isomerase D	4	-159849728	AI014573	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
219400_at	0.292	5.054	3.402	3.875e-03	0.256	-1.782	CNTNAP1	contactin associated protein 1	17	38088157	NM_003632	8506	17q21	Hs.408730	10	receptor activity SH3/SH2 adaptor activity receptor binding integral to plasma membrane cell adhesion signal transduction membrane SH3 domain binding paranode region of axon	Cell adhesion molecules (CAMs)
226124_at	0.411	5.319	3.402	3.877e-03	0.256	-1.783	ZFP90	zinc finger protein 90 homolog (mouse)	16	67131161	AA747309	146198	16q22.1	Hs.461074 Hs.709017	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214681_at	0.238	4.794	3.401	3.879e-03	0.256	-1.783	GK	glycerol kinase	X	30581396	AI830490	2710	Xp21.3	Hs.1466	20	nucleotide binding glycerol kinase activity glycerol kinase activity ATP binding cytoplasm mitochondrion mitochondrial outer membrane cytosol carbohydrate metabolic process glycerol-3-phosphate metabolic process membrane transferase activity	Glycerolipid metabolism Metabolic pathways PPAR signaling pathway
218150_at	-0.396	9.360	-3.401	3.880e-03	0.256	-1.783	ARL5A	ADP-ribosylation factor-like 5A	2	-152365725	NM_012097	26225	2q23.3	Hs.470233	6	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
219256_s_at	0.411	4.260	3.399	3.897e-03	0.256	-1.787	SH3TC1	SH3 domain and tetratricopeptide repeats 1	4	8251959	NM_018986	54436	4p16.1	Hs.479116	5	binding cellular_component biological_process
203555_at	0.251	6.307	3.399	3.898e-03	0.256	-1.787	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	2	130830049	NM_014369	26469	2q21.1	Hs.516390 Hs.591549	16	non-membrane spanning protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity
228765_at	-0.570	8.877	-3.399	3.899e-03	0.256	-1.788	GTF2IRD2	GTF2I repeat domain containing 2	7	-73848419	BG032651	84163	7q11.23	Hs.647017 Hs.647039	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription
205603_s_at	-0.942	6.759	-3.399	3.901e-03	0.256	-1.788	DIAPH2	diaphanous homolog 2 (Drosophila)	X	95826317, 95826317	NM_007309	1730	Xq21.33	Hs.226483 Hs.716101	14	cytokinesis actin binding receptor binding cytoplasm early endosome Golgi apparatus cytosol multicellular organismal development cellular component organization Rho GTPase binding actin cytoskeleton organization cell differentiation oogenesis	Regulation of actin cytoskeleton
226364_at	0.393	5.856	3.398	3.903e-03	0.256	-1.789	HIP1	huntingtin interacting protein 1	7	-75001344	AU145049	3092	7q11.23	Hs.329266 Hs.619089	31	actin binding structural constituent of cytoskeleton membrane fraction nucleus cytoplasm Golgi apparatus cytoskeleton endocytosis induction of apoptosis activation of caspase activity cell death membrane cell differentiation clathrin binding clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding regulation of apoptosis regulation of transcription positive regulation of receptor-mediated endocytosis clathrin coat assembly	Huntington's disease
1568618_a_at	-0.641	7.864	-3.398	3.905e-03	0.256	-1.789	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	BC038440	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
219827_at	-1.107	8.156	-3.398	3.910e-03	0.256	-1.790	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	11	-73391459, -73388975	NM_003356	7352	11q13	Hs.101337 Hs.621879	108	response to superoxide response to hypoxia transporter activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process transport mitochondrial transport respiratory gaseous exchange proton transport membrane integral to membrane oxidative phosphorylation uncoupler activity
225790_at	-0.672	7.260	-3.397	3.912e-03	0.256	-1.791	MSRB3	methionine sulfoxide reductase B3	12	63958754	AL048386	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
210164_at	0.459	4.117	3.396	3.921e-03	0.256	-1.793	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	14	-24170003	J03189	3002	14q11.2	Hs.1051	142	immunological synapse serine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis apoptosis cleavage of lamin peptidase activity cytolysis	Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
213374_x_at	-0.394	8.400	-3.395	3.933e-03	0.257	-1.795	HIBCH	3-hydroxyisobutyryl-Coenzyme A hydrolase	2	-190777604	AW000964	26275	2q32.2	Hs.656685	8	3-hydroxyisobutyryl-CoA hydrolase activity protein binding mitochondrion metabolic process branched chain family amino acid catabolic process hydrolase activity	Valine, leucine and isoleucine degradation beta-Alanine metabolism Propanoate metabolism Metabolic pathways
224565_at	-0.685	10.792	-3.394	3.943e-03	0.257	-1.798	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	BE675516	283131	11q13.1	Hs.523789 Hs.648467	6
205414_s_at	0.518	4.890	3.393	3.947e-03	0.257	-1.799	RICH2	Rho-type GTPase-activating protein RICH2	17	12633553	NM_014859	9912	17p12	Hs.499758	7	GTPase activator activity protein binding intracellular cytoplasm signal transduction
221840_at	0.423	3.960	3.391	3.960e-03	0.258	-1.802	PTPRE	protein tyrosine phosphatase, receptor type, E	10	129595314, 129735802	AA775177	5791	10q26	Hs.127022	33	transmembrane receptor protein tyrosine phosphatase activity protein binding cytoplasm plasma membrane protein amino acid phosphorylation protein amino acid dephosphorylation integral to membrane hydrolase activity
207349_s_at	-1.155	8.615	-3.387	3.994e-03	0.259	-1.809	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	11	-73391459, -73388975	NM_022803	7352	11q13	Hs.101337 Hs.621879	108	response to superoxide response to hypoxia transporter activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process transport mitochondrial transport respiratory gaseous exchange proton transport membrane integral to membrane oxidative phosphorylation uncoupler activity
204311_at	0.325	5.735	3.387	3.994e-03	0.259	-1.809	ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	17	7494978	NM_001678	482	17p13.1	Hs.712542	22	sodium:potassium-exchanging ATPase activity protein binding ATP biosynthetic process ion transport potassium ion transport sodium ion transport membrane integral to membrane potassium ion binding sodium ion binding	Cardiac muscle contraction
200895_s_at	-0.482	8.114	-3.387	3.996e-03	0.259	-1.810	FKBP4	FK506 binding protein 4, 59kDa	12	2774368	NM_002014	2288	12p13.33	Hs.524183 Hs.713721	47	peptidyl-prolyl cis-trans isomerase activity ATP binding GTP binding FK506 binding intracellular nucleus nucleolus cytoplasm protein folding steroid hormone receptor complex assembly copper ion transport embryo implantation isomerase activity protein binding, bridging heat shock protein binding protein complex localization glucocorticoid receptor binding male sex differentiation phosphoprotein binding
229246_at	0.459	6.236	3.385	4.012e-03	0.259	-1.813	FLJ44342	hypothetical LOC645460	17		AI803504	645460	17q22	Hs.68714 Hs.710026	1
215718_s_at	-0.338	3.970	-3.385	4.014e-03	0.259	-1.814	PHF3	PHD finger protein 3	6	64414389	AI949220	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
223451_s_at	0.525	6.374	3.384	4.022e-03	0.259	-1.816	CKLF	chemokine-like factor	16	65143966, 65143972	AF096895	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
200992_at	-0.289	9.968	-3.381	4.048e-03	0.260	-1.821	IPO7	importin 7	11	9362744	AL137335	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
210219_at	0.327	3.704	3.380	4.057e-03	0.261	-1.823	SP100	SP100 nuclear antigen	2	230989114, 230989114	U36501	6672	2q37.1	Hs.369056	34	negative regulation of transcription from RNA polymerase II promoter DNA binding transcription coactivator activity transcription corepressor activity nucleus chromosome DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator PML body kinase binding protein domain specific binding response to type I interferon response to type I interferon response to interferon-gamma response to interferon-gamma protein homodimerization activity negative regulation of transcription factor activity interspecies interaction between organisms positive regulation of transcription, DNA-dependent negative regulation of cell motion interferon-gamma-mediated signaling pathway type I interferon-mediated signaling pathway
1556839_s_at	0.539	4.206	3.378	4.072e-03	0.261	-1.827	SPTBN5	spectrin, beta, non-erythrocytic 5	15	-39927635	AA515490	51332	15q21	Hs.709819	3	actin binding cytoplasm cytoskeleton spectrin membrane actin cytoskeleton organization actin filament capping
226907_at	-1.024	7.905	-3.377	4.083e-03	0.261	-1.829	PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C	6	150505880	N32557	81706	6q24.3-q25.3	Hs.486798	10	protein serine/threonine phosphatase inhibitor activity protein binding cytoplasm membrane regulation of phosphorylation
207537_at	-0.909	7.178	-3.373	4.110e-03	0.262	-1.835	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	X	-54976314	NM_002625	5207	Xp11.21	Hs.444304	11	nucleotide binding 6-phosphofructo-2-kinase activity 6-phosphofructo-2-kinase activity fructose-2,6-bisphosphate 2-phosphatase activity fructose-2,6-bisphosphate 2-phosphatase activity ATP binding cytosol fructose 2,6-bisphosphate metabolic process gluconeogenesis glycolysis protein kinase cascade metabolic process kinase activity transferase activity hydrolase activity identical protein binding 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex	Fructose and mannose metabolism
223479_s_at	0.280	6.600	3.372	4.122e-03	0.262	-1.838	CHCHD5	coiled-coil-helix-coiled-coil-helix domain containing 5	2	113058506	BC004498	84269	2q13	Hs.375707	3
219667_s_at	0.259	2.368	3.370	4.137e-03	0.262	-1.841	BANK1	B-cell scaffold protein with ankyrin repeats 1	4	102930786, 102954005	NM_017935	55024	4q24	Hs.480400	11	B cell activation
227404_s_at	-2.050	5.795	-3.369	4.149e-03	0.262	-1.843	EGR1	early growth response 1	5	137829079	AI459194	1958	5q31.1	Hs.326035 Hs.708393	174	negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent learning or memory zinc ion binding transcription activator activity T cell differentiation positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding	Prion diseases
228618_at	0.344	5.843	3.368	4.159e-03	0.262	-1.846	PEAR1	platelet endothelial aggregation receptor 1	1	155130146	AL040178	375033	1q23.1	Hs.142003 Hs.715070	3	plasma membrane integral to membrane
41858_at	0.334	6.059	3.368	4.160e-03	0.262	-1.846	PGAP2	post-GPI attachment to proteins 2	11	3775529, 3775624, 3775707, 3775765, 3785815, 3786341	AL049261	27315	11p15.5	Hs.133968	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus GPI anchor biosynthetic process protein transporter activity membrane integral to membrane
215667_x_at	0.375	5.992	3.367	4.161e-03	0.262	-1.846	PMS2L1	postmeiotic segregation increased 2-like 1 pseudogene	7	-99756198	AI375694	5379	7q22.1	Hs.634244 Hs.661055 Hs.709266	7	molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding
227282_at	0.390	4.869	3.367	4.166e-03	0.262	-1.847	PCDH19	protocadherin 19	X	-99433297	AB037734	57526	Xq13.3	Hs.4993	12	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
235604_x_at	0.533	4.708	3.365	4.186e-03	0.263	-1.852	ZNF493	zinc finger protein 493	19	21371760, 21371760	AI758697	284443	19p12	Hs.656558	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1555516_at	-0.511	3.965	-3.364	4.193e-03	0.263	-1.853	FOXP2	forkhead box P2	7	113842287	BC018016	93986	7q31	Hs.656280	50	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding caudate nucleus development putamen development protein homodimerization activity sequence-specific DNA binding metal ion binding
204607_at	2.175	7.980	3.363	4.197e-03	0.263	-1.854	HMGCS2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	1	-120092525	NM_005518	3158	1p13-p12	Hs.59889	13	hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity mitochondrion mitochondrial inner membrane mitochondrial matrix cholesterol biosynthetic process response to nutrient metabolic process isoprenoid biosynthetic process transferase activity response to drug response to peptide hormone stimulus	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
209824_s_at	0.985	6.368	3.363	4.200e-03	0.263	-1.854	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11	13255900	AB000812	406	11p15	Hs.65734	37	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction circadian rhythm aryl hydrocarbon receptor binding positive regulation of transcription from RNA polymerase II promoter Hsp90 protein binding	Circadian rhythm - mammal
226206_at	-0.486	8.209	-3.363	4.202e-03	0.263	-1.855	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	7	1536893	BG231691	7975	7p22.3	Hs.520612	14	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent nervous system development sequence-specific DNA binding
202322_s_at	-0.358	8.013	-3.360	4.229e-03	0.263	-1.861	GGPS1	geranylgeranyl diphosphate synthase 1	1	233558375, 233558491	NM_004837	9453	1q43	Hs.719270	13	dimethylallyltranstransferase activity farnesyltranstransferase activity geranyltranstransferase activity soluble fraction cytoplasm isoprenoid biosynthetic process transferase activity	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
200731_s_at	-0.609	9.773	-3.359	4.233e-03	0.263	-1.862	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	AW165960	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
214757_at	0.308	3.961	3.359	4.234e-03	0.263	-1.862	PMS2L2	postmeiotic segregation increased 2-like 2 pseudogene	7	-74815899, 72114615	BG178274	5380	7q11-q22	Hs.292996 Hs.661055 Hs.675888	4	molecular_function ATP binding cellular_component mismatch repair biological_process mismatched DNA binding
211597_s_at	0.475	7.451	3.359	4.235e-03	0.263	-1.862	HOPX	HOP homeobox	4	-57208910, -57208910	AB059408	84525	4q11-q12	Hs.654864	25	negative regulation of transcription from RNA polymerase II promoter trophectodermal cell differentiation transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development heart development regulation of heart contraction transcription repressor activity histone deacetylation positive regulation of skeletal muscle regeneration sequence-specific DNA binding negative regulation of cell differentiation lung alveolus development positive regulation of striated muscle cell differentiation
213625_at	0.293	4.722	3.357	4.250e-03	0.264	-1.865	ZKSCAN4	zinc finger with KRAB and SCAN domains 4	6	-28320468	AW190088	387032	6p21.33-p21.31	Hs.44720	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200730_s_at	-0.998	8.533	-3.357	4.253e-03	0.264	-1.866	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	BF576710	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
203700_s_at	0.494	4.945	3.355	4.266e-03	0.264	-1.868	DIO2	deiodinase, iodothyronine, type II	14	-79733621, -79733621	NM_013989	1734	14q24.2-q24.3	Hs.202354	61	selenocysteine incorporation thyroxine 5'-deiodinase activity thyroid hormone generation selenium binding membrane integral to membrane thyroid hormone catabolic process hormone biosynthetic process oxidation reduction
218843_at	0.602	6.142	3.354	4.279e-03	0.265	-1.871	FNDC4	fibronectin type III domain containing 4	2	-27568254	NM_022823	64838	2p23.3	Hs.27836 Hs.718524	6	membrane integral to membrane
218966_at	0.503	6.083	3.353	4.291e-03	0.265	-1.874	MYO5C	myosin VC	15	-50271811	NM_018728	55930	15q21	Hs.487036	6	nucleotide binding motor activity calmodulin binding ATP binding myosin complex actin filament binding
226083_at	-0.875	7.027	-3.352	4.294e-03	0.265	-1.874	TMEM70	transmembrane protein 70	8	75050983	AA886902	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
229344_x_at	0.480	5.761	3.349	4.324e-03	0.266	-1.881	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AW135012	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
1557347_at	0.228	5.498	3.348	4.332e-03	0.266	-1.882	MCPH1	microcephalin 1	8	6251528	N21605	79648	8p23.1	Hs.709634	32	intracellular centrosome
214364_at	0.325	6.133	3.348	4.332e-03	0.266	-1.882	MTERFD2	MTERF domain containing 2	2	-241683654, -241675182	W84525	130916	2q37.3	Hs.159556	5
236953_s_at	0.494	4.246	3.348	4.332e-03	0.266	-1.882	NHLRC3	NHL repeat containing 3	13	38510454	N25548	387921	13q13.3	Hs.507783	1	extracellular region
91684_g_at	0.407	6.190	3.346	4.351e-03	0.266	-1.886	EXOSC4	exosome component 4	8	145205509	AI571298	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
225326_at	-0.331	7.474	-3.345	4.356e-03	0.266	-1.887	RBM27	RNA binding motif protein 27	5	145563355	AB037732	54439	5q32	Hs.61441	8	nucleotide binding RNA binding nucleus cytoplasm zinc ion binding nuclear speck metal ion binding
222916_s_at	-0.407	5.661	-3.344	4.367e-03	0.266	-1.890	HDLBP	high density lipoprotein binding protein	2	-241815351, -241815351	AF116718	3069	2q37.3	Hs.471851	25	RNA binding protein binding nucleus cytoplasm plasma membrane lipid metabolic process lipid transport steroid metabolic process cholesterol metabolic process lipid binding high-density lipoprotein particle
205251_at	-1.140	7.774	-3.344	4.367e-03	0.266	-1.890	PER2	period homolog 2 (Drosophila)	2	-238817417	NM_022817	8864	2q37.3	Hs.58756	46	signal transducer activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm	Circadian rhythm - mammal
213534_s_at	0.265	3.553	3.340	4.401e-03	0.268	-1.896	PASK	PAS domain containing serine/threonine kinase	2	-241694187	D50925	23178	2q37.3	Hs.397891	16	nucleotide binding protein serine/threonine kinase activity signal transducer activity ATP binding cytoplasm Golgi apparatus regulation of transcription, DNA-dependent protein amino acid phosphorylation signal transduction transferase activity identical protein binding
238952_x_at	0.271	3.760	3.336	4.443e-03	0.270	-1.905	ZNF829	zinc finger protein 829	19	-42074092	BF439163	374899	19q13.12	Hs.124047	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235729_at	0.666	5.930	3.333	4.467e-03	0.271	-1.910	ZNF514	zinc finger protein 514	2	-95177126	T93113	84874	2q11.1	Hs.655109	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222736_s_at	-0.539	6.886	-3.331	4.482e-03	0.271	-1.913	TMEM38B	transmembrane protein 38B	9	107496645	BC000049	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
223267_at	-0.360	7.695	-3.331	4.488e-03	0.271	-1.914	RG9MTD1	RNA (guanine-9-) methyltransferase domain containing 1	3	102763401	AF226052	54931	3q12.3	Hs.643184 Hs.715724	3	protein binding mitochondrion tRNA processing methyltransferase activity transferase activity
241198_s_at	0.235	2.629	3.330	4.495e-03	0.271	-1.916	C11orf70	chromosome 11 open reading frame 70	11	101423408	BE645435	85016	11q22.1	Hs.98328	3
240728_at	0.276	4.796	3.330	4.496e-03	0.271	-1.916	PLCB4	phospholipase C, beta 4	20	9024931	AI224105	5332	20p12	Hs.472101	17	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding intracellular signaling cascade lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
1554452_a_at	0.393	5.420	3.330	4.496e-03	0.271	-1.916	C7orf68	chromosome 7 open reading frame 68	7	127883119	BC001863	29923	7q32.1	Hs.710088	9	molecular_function cellular_component response to stress membrane integral to membrane
1555950_a_at	-0.603	7.589	-3.330	4.497e-03	0.271	-1.916	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	1	205561439	CA448665	1604	1q32	Hs.126517	118	soluble fraction plasma membrane integral to plasma membrane complement activation, classical pathway elevation of cytosolic calcium ion concentration anchored to membrane innate immune response membrane raft respiratory burst	Complement and coagulation cascades Hematopoietic cell lineage
232874_at	0.591	4.632	3.326	4.532e-03	0.272	-1.923	DOCK9	dedicator of cytokinesis 9	13	-98310435, -98310435, -98243741, -98243741	AU146550	23348	13q32.3	Hs.596105	15	guanyl-nucleotide exchange factor activity GTP binding cellular_component biological_process membrane GTPase binding
203178_at	-1.120	8.782	-3.326	4.533e-03	0.272	-1.923	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	NM_001482	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
205334_at	0.547	8.764	3.326	4.534e-03	0.272	-1.923	S100A1	S100 calcium binding protein A1	1	151867496	NM_006271	6271	1q21	Hs.515715	55	calcium ion binding cytoplasm intracellular signaling cascade regulation of heart contraction zinc ion binding sarcoplasmic reticulum protein homodimerization activity protein complex S100 beta binding S100 alpha binding ATPase binding
226284_at	-0.593	5.152	-3.324	4.551e-03	0.273	-1.927	ZBTB2	zinc finger and BTB domain containing 2	6	-151726942	BF111616	57621	6q25.1	Hs.520073	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
219290_x_at	0.339	4.887	3.322	4.566e-03	0.274	-1.930	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	NM_014395	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
200958_s_at	-0.342	9.015	-3.320	4.585e-03	0.274	-1.933	SDCBP	syndecan binding protein (syntenin)	8	59628281	NM_005625	6386	8q12	Hs.200804	39	interleukin-5 receptor binding nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton plasma membrane interleukin-5 receptor complex adherens junction focal adhesion protein targeting to membrane substrate-bound cell migration, cell extension intracellular signaling cascade Ras protein signal transduction synaptic transmission cytoskeletal adaptor activity actin cytoskeleton organization cell junction melanosome syndecan binding protein heterodimerization activity protein N-terminus binding
219656_at	0.294	6.482	3.320	4.587e-03	0.274	-1.934	PCDH12	protocadherin 12	5	-141304713	NM_016580	51294	5q31	Hs.439474	10	calcium ion binding protein binding plasma membrane integral to plasma membrane cell-cell junction cell adhesion homophilic cell adhesion neuron recognition calcium-dependent cell-cell adhesion
225733_at	0.292	5.786	3.318	4.612e-03	0.275	-1.939	B3GALT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6	1	1157491	AI890557	126792	1p36.33	Hs.284284	4	Golgi apparatus Golgi medial cisterna glycosaminoglycan biosynthetic process protein amino acid glycosylation UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding galactosylxylosylprotein 3-beta-galactosyltransferase activity	Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways
226313_at	0.339	4.719	3.316	4.626e-03	0.275	-1.941	C10orf35	chromosome 10 open reading frame 35	10	71060008	H49529	219738	10q22.1	Hs.522992	5	protein binding membrane integral to membrane
218411_s_at	0.371	5.395	3.316	4.628e-03	0.275	-1.942	MBIP	MAP3K12 binding inhibitory protein 1	14	-35837514	NM_016586	51562	14q13.3	Hs.368647	8	inactivation of MAPK activity involved in osmosensory signaling pathway protein kinase inhibitor activity nucleus nucleolus cytoplasm identical protein binding
212899_at	0.389	5.634	3.312	4.664e-03	0.276	-1.949	CDC2L6	cell division cycle 2-like 6 (CDK8-like)	6	-111037873	AB028951	23097	6q21	Hs.719138	10	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
222116_s_at	0.453	5.189	3.311	4.674e-03	0.276	-1.951	TBC1D16	TBC1 domain family, member 16	17	-75528413	AL157485	125058	17q25.3	Hs.369819	4	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
1569986_x_at	-0.961	11.920	-3.310	4.680e-03	0.276	-1.952	TNNT3	troponin T type 3 (skeletal, fast)	11	1897374	BF789882	7140	11p15.5	Hs.73454	21	skeletal muscle contraction actin binding tropomyosin binding tropomyosin binding troponin complex regulation of striated muscle contraction troponin C binding calcium-dependent ATPase activity troponin I binding regulation of ATPase activity calcium-dependent protein binding
244741_s_at	1.118	6.388	3.310	4.688e-03	0.276	-1.953	MGC9913	hypothetical protein MGC9913	19		BE855713	386759	19q13.43	Hs.23133	1
213795_s_at	0.310	4.724	3.309	4.692e-03	0.276	-1.954	PTPRA	protein tyrosine phosphatase, receptor type, A	20	2792840, 2802141, 2851852	AL121905	5786	20p13	Hs.269577	58	transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid phosphorylation protein amino acid dephosphorylation membrane hydrolase activity
205981_s_at	-0.748	6.685	-3.308	4.707e-03	0.277	-1.957	ING2	inhibitor of growth family, member 2	4	184663213	NM_001564	3622	4q35.1	Hs.107153	27	DNA binding chromatin binding protein binding nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding transcription activator activity chromatin modification Sin3 complex CCAAT-binding factor complex regulation of growth positive regulation of transcription metal ion binding
209244_s_at	-0.273	8.255	-3.307	4.714e-03	0.277	-1.958	KIF1C	kinesin family member 1C	17	4841999	BE885926	10749	17p13.2	Hs.435120	8	nucleotide binding microtubule motor activity ATP binding endoplasmic reticulum Golgi apparatus microtubule retrograde vesicle-mediated transport, Golgi to ER microtubule-based movement
210275_s_at	-0.660	10.431	-3.307	4.715e-03	0.277	-1.958	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AF062347	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
223583_at	0.357	5.061	3.306	4.727e-03	0.277	-1.961	TNFAIP8L2	tumor necrosis factor, alpha-induced protein 8-like 2	1	149395728	AF271774	79626	1q21.3	Hs.709522	2	protein binding innate immune response
213812_s_at	0.511	7.145	3.305	4.733e-03	0.277	-1.962	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta	12	-120165773, -120159877, -120159877	AK024748	10645	12q24.2	Hs.297343	18	MAPKKK cascade nucleotide binding calmodulin-dependent protein kinase activity protein tyrosine kinase activity calcium ion binding calmodulin binding ATP binding intracellular cytoplasm transferase activity calcium-mediated signaling regulation of protein kinase activity positive regulation of transcription protein amino acid autophosphorylation	Adipocytokine signaling pathway
201380_at	-0.384	5.827	-3.305	4.736e-03	0.277	-1.962	CRTAP	cartilage associated protein	3	33130453	NM_006371	10491	3p22.3	Hs.719160	10	extracellular region proteinaceous extracellular matrix
238592_at	-1.188	8.949	-3.303	4.753e-03	0.277	-1.966	PDLIM3	PDZ and LIM domain 3	4	-186659844	BE840636	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
224666_at	0.324	7.798	3.302	4.758e-03	0.277	-1.967	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	16	-27143815	AF161451	197370	16p12.1	Hs.284295	6	nucleus DNA repair DNA recombination response to DNA damage stimulus zinc ion binding metal ion binding
222617_s_at	-0.532	7.394	-3.302	4.759e-03	0.277	-1.967	C10orf84	chromosome 10 open reading frame 84	10	-120058561	AI147026	63877	10q26.11	Hs.372309	5
213001_at	-0.687	7.322	-3.302	4.763e-03	0.277	-1.967	ANGPTL2	angiopoietin-like 2	9	-128889448	AF007150	23452	9q34	Hs.653262	11	receptor binding extracellular region extracellular space signal transduction multicellular organismal development
232063_x_at	0.416	4.132	3.302	4.766e-03	0.277	-1.968	FARSB	phenylalanyl-tRNA synthetase, beta subunit	2	-223144405	AW024617	10056	2q36.1	Hs.471452	14	nucleotide binding magnesium ion binding RNA binding phenylalanine-tRNA ligase activity ATP binding soluble fraction cytoplasm translation phenylalanyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
201298_s_at	-0.338	7.583	-3.301	4.776e-03	0.277	-1.970	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	2	-74236718	BC003398	55233	2p13.1	Hs.196437	12	protein binding zinc ion binding metal ion binding
227406_at	0.466	6.757	3.300	4.783e-03	0.277	-1.971	LOC100129387	hypothetical LOC100129387	15	48433662	AI286203	100129387	15q21.2	Hs.659360	1
201520_s_at	-0.544	9.375	-3.299	4.788e-03	0.277	-1.972	GRSF1	G-rich RNA sequence binding factor 1	4	-71900362, -71900362	BF034561	2926	4q13	Hs.309763	6	mRNA binding cytoplasm mRNA polyadenylation
219441_s_at	0.389	5.096	3.299	4.796e-03	0.277	-1.974	LRRK1	leucine-rich repeat kinase 1	15	99276982	NM_024652	79705	15q26.3	Hs.407918	16	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding GTP binding intracellular cytoplasm protein amino acid phosphorylation small GTPase mediated signal transduction transferase activity manganese ion binding
218735_s_at	0.679	5.646	3.298	4.797e-03	0.277	-1.974	ZNF544	zinc finger protein 544	19	63431881	AA349848	27300	19q13.43	Hs.438994	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
220650_s_at	0.286	5.813	3.298	4.800e-03	0.277	-1.975	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5	16	65840355	NM_004594	6553	16q22.1	Hs.439650	11	cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane sodium ion binding
214265_at	0.373	5.193	3.297	4.812e-03	0.277	-1.977	ITGA8	integrin, alpha 8	10	-15599093	AI193623	8516	10p13	Hs.171311	15	metanephros development receptor activity calcium ion binding protein binding cell-matrix adhesion integrin-mediated signaling pathway multicellular organismal development nervous system development memory integrin complex membrane integral to membrane cell-cell adhesion cell projection organization cell differentiation extracellular matrix organization positive regulation of transforming growth factor beta receptor signaling pathway inner ear morphogenesis apical part of cell	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
226676_at	0.397	4.388	3.293	4.850e-03	0.279	-1.984	ZNF521	zinc finger protein 521	18	-20895885	AK021452	25925	18q11.2	Hs.116935	9
212188_at	0.745	7.397	3.292	4.860e-03	0.279	-1.986	KCTD12	potassium channel tetramerisation domain containing 12	13	-76352304	AA551075	115207	13q22.3	Hs.644125	14	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
218706_s_at	0.682	5.188	3.289	4.888e-03	0.280	-1.991	GRAMD3	GRAM domain containing 3	5	125723686, 125786767, 125828685	AW575493	65983	5q23.2	Hs.363558	6
232011_s_at	0.411	6.301	3.289	4.895e-03	0.280	-1.992	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	AL118520	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
228155_at	0.812	9.301	3.287	4.913e-03	0.280	-1.995	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	BF512388	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
235122_at	0.513	4.554	3.286	4.920e-03	0.280	-1.997	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	1	-41748270	AI800713	59269	1p34	Hs.648369 Hs.715958	12	DNA binding intracellular nucleus cytoplasm zinc ion binding transcription activator activity positive regulation of transcription metal ion binding
227631_at	0.340	4.612	3.285	4.928e-03	0.280	-1.998	ABI2	abl-interactor 2	2	203901247	BF058849	10152	2q33	Hs.471156	22	DNA binding SH3/SH2 adaptor activity cytoplasm cytoplasm cytosol cytoskeleton cell motion cytoskeleton organization cytoskeletal adaptor activity actin polymerization or depolymerization cell migration SH3 domain binding peptidyl-tyrosine phosphorylation kinase binding lamellipodium filopodium	Regulation of actin cytoskeleton
205830_at	1.379	4.555	3.284	4.939e-03	0.280	-2.000	CLGN	calmegin	4	-141529056	NM_004362	1047	4q28.3-q31.1	Hs.86368	11	calcium ion binding endoplasmic reticulum protein folding single fertilization membrane integral to membrane unfolded protein binding
202845_s_at	-0.368	7.788	-3.283	4.950e-03	0.281	-2.002	RALBP1	ralA binding protein 1	18	9465529	NM_006788	10928	18p11.3	Hs.528993 Hs.719181	42	GTPase activator activity protein binding intracellular transport chemotaxis signal transduction small GTPase mediated signal transduction membrane ATPase activity Ral GTPase binding Rac GTPase activator activity regulation of GTPase activity positive regulation of Cdc42 GTPase activity ATPase activity, coupled to movement of substances Rac GTPase binding	Pathways in cancer Pancreatic cancer
201832_s_at	-0.421	9.929	-3.282	4.968e-03	0.281	-2.005	USO1	USO1 homolog, vesicle docking protein (yeast)	4	76868852	NM_003715	8615	4q21.1	Hs.292689	34	Golgi membrane protein binding cytoplasm microsome Golgi apparatus cytosol intracellular protein transport protein transporter activity membrane vesicle-mediated transport vesicle fusion with Golgi apparatus perinuclear region of cytoplasm
217591_at	-0.655	5.835	-3.280	4.981e-03	0.281	-2.008	SKIL	SKI-like oncogene	3	171558166, 171560104	BF725121	6498	3q26	Hs.581632	34	nucleotide binding transcription corepressor activity transforming growth factor beta receptor, cytoplasmic mediator activity protein binding nucleus transcription from RNA polymerase II promoter signal transduction multicellular organismal development
232473_at	0.405	4.405	3.277	5.012e-03	0.282	-2.013	PRPF18	PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae)	10	13668944	AU144329	8559	10p13	Hs.161181	6	nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck
1556049_at	0.882	6.283	3.276	5.024e-03	0.282	-2.016	RTN4	reticulon 4	2	-55052830, -55052830, -55052830	CA428769	57142	2p16.3	Hs.704007	73	protein binding nuclear envelope endoplasmic reticulum membrane integral to membrane negative regulation of anti-apoptosis integral to endoplasmic reticulum membrane regulation of cell migration negative regulation of axon extension regulation of apoptosis
235082_at	-0.499	4.866	-3.275	5.037e-03	0.282	-2.018	PCNX	pecanex homolog (Drosophila)	14	70443874	BG024649	22990	14q24.2	Hs.446559	10	membrane integral to membrane
241233_x_at	0.272	7.465	3.275	5.037e-03	0.282	-2.018	C21orf81	ankyrin repeat domain 20 family, member A3 pseudogene	21	-14237966	AI978581	391267	21q11.2	Hs.364456	2
210867_at	-0.408	5.238	-3.275	5.040e-03	0.282	-2.018	CNOT4	CCR4-NOT transcription complex, subunit 4	7	-134723303, -134697088	AF180475	4850	7q22-qter	Hs.490224	7	nucleotide binding RNA binding protein binding nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process regulation of transcription metal ion binding	RNA degradation
202077_at	0.308	12.059	3.273	5.058e-03	0.283	-2.022	NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	16	-23499835	NM_005003	4706	16p12.2	Hs.189716	14	acyl carrier activity fatty acid binding calcium ion binding mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone fatty acid biosynthetic process transport NADH dehydrogenase (ubiquinone) activity electron transport chain phosphopantetheine binding mitochondrial membrane mitochondrial membrane cofactor binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
215734_at	0.373	4.771	3.272	5.067e-03	0.283	-2.023	C19orf36	chromosome 19 open reading frame 36	19	2047867	AW182303	113177	19p13.3	Hs.424049	3	extracellular region
1569076_a_at	0.360	3.324	3.271	5.073e-03	0.283	-2.024	ZNF836	zinc finger protein 836	19	-57349936	BE791720	162962	19q13.41	Hs.631584	1	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231567_s_at	0.266	5.634	3.270	5.088e-03	0.284	-2.027	CCDC62	coiled-coil domain containing 62	12	121825025	AI027946	84660	12q24.31	Hs.592008	6
214039_s_at	-0.636	11.019	-3.269	5.097e-03	0.284	-2.028	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	T15777	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
213820_s_at	0.251	4.770	3.269	5.097e-03	0.284	-2.028	STARD5	StAR-related lipid transfer (START) domain containing 5	15	-79392061	T54159	80765	15q26	Hs.513075	12	cytosol steroid biosynthetic process lipid transport lipid binding
221221_s_at	0.398	6.145	3.269	5.100e-03	0.284	-2.029	KLHL3	kelch-like 3 (Drosophila)	5	-136981087	NM_017415	26249	5q31	Hs.655084	8	actin binding structural molecule activity protein binding cytoplasm cytoskeleton modification-dependent protein catabolic process
224857_s_at	-0.347	7.320	-3.266	5.133e-03	0.284	-2.035	POLR1D	polymerase (RNA) I polypeptide D, 16kDa	13	27094002, 27094028	BE378670	51082	13q12.2	Hs.507584	15	DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm transcription protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
239517_at	0.733	6.000	3.265	5.138e-03	0.284	-2.036	ITGB6	integrin, beta 6	2	-160666478	AA609987	3694	2q24.2	Hs.470399	44	receptor activity protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane interspecies interaction between organisms	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
65630_at	0.393	6.360	3.265	5.141e-03	0.284	-2.036	TMEM80	transmembrane protein 80	11	685615	AI742455	283232	11p15.5	Hs.448664	2	membrane integral to membrane
232284_at	0.450	4.777	3.265	5.145e-03	0.284	-2.037	PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	3	-63971270	AI206345	9861	3p14.1	Hs.152536	35	proteasome complex protein binding cytosol proteolysis ATPase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
211086_x_at	0.238	3.870	3.264	5.145e-03	0.284	-2.037	NEK1	NIMA (never in mitosis gene a)-related kinase 1	4	-170551003	Z25431	4750	4q33	Hs.481181	11	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division
222154_s_at	-0.497	9.172	-3.264	5.151e-03	0.284	-2.038	SPATS2L	spermatogenesis associated, serine-rich 2-like	2	200878848, 200879229, 200879600	AK002064	26010	2q33.1	Hs.120323	9
218264_at	-0.286	7.406	-3.262	5.172e-03	0.285	-2.042	BCCIP	BRCA2 and CDKN1A interacting protein	10	127502093, 127502093, 127502093	NM_016567	56647	10q26.1	Hs.370292 Hs.715543	31	regulation of cyclin-dependent protein kinase activity protein binding nucleus DNA repair response to DNA damage stimulus cell cycle
218710_at	-0.322	6.208	-3.260	5.193e-03	0.285	-2.045	TTC27	tetratricopeptide repeat domain 27	2	32706632	NM_017735	55622	2p22.3	Hs.468125	6	protein binding cellular_component biological_process
57588_at	-1.064	8.282	-3.259	5.203e-03	0.285	-2.047	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	20	19141289	R62432	57419	20p13	Hs.654790	2	calcium ion binding ion transport potassium ion transport sodium ion transport calcium ion transport calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral to membrane potassium ion binding sodium ion binding
238840_at	0.575	5.145	3.259	5.203e-03	0.285	-2.047	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2	238200962, 238265545, 238265545	AW082668	9208	2q37.3	Hs.471779	16	DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity
226047_at	0.366	7.129	3.259	5.208e-03	0.285	-2.048	MRVI1	murine retrovirus integration site 1 homolog	11	-10551213, -10551213, -10551213	N66571	10335	11p15	Hs.501898	13	cytoplasm endoplasmic reticulum membrane membrane integral to membrane sarcoplasmic reticulum perinuclear region of cytoplasm	Vascular smooth muscle contraction
235521_at	0.441	6.453	3.258	5.210e-03	0.285	-2.048	HOXA3	homeobox A3	7	-27112333, -27112333, -27112333	AW137982	3200	7p15-p14	Hs.659337	18	blood vessel remodeling transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation specification of organ position glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding thymus development organ formation embryonic skeletal system morphogenesis cartilage development parathyroid gland development
235408_x_at	0.622	3.536	3.257	5.231e-03	0.285	-2.052	ZNF117	zinc finger protein 117	7	-64072264	AW058673	51351	7q11.21	Hs.250693	5	molecular_function transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding metal ion binding
228077_at	0.520	7.456	3.256	5.237e-03	0.285	-2.053	MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)	19	13736336	AK026666	84245	19p13.2	Hs.439370	11	cellular amino acid biosynthetic process methionine biosynthetic process isomerase activity identical protein binding cellular biosynthetic process S-methyl-5-thioribose-1-phosphate isomerase activity
1558954_at	0.316	5.816	3.255	5.244e-03	0.285	-2.054	SNORA78	small nucleolar RNA, H/ACA box 78	16	1955185	BC028232	677844	16p13.3	Hs.707294	2
230025_at	0.358	5.927	3.255	5.252e-03	0.285	-2.055	GJD3	gap junction protein, delta 3, 31.9kDa	17	-35770430	BF508941	125111	17q21.2	Hs.444663	8	protein binding plasma membrane integral to plasma membrane connexon complex cell communication cell surface gap junction assembly cell junction
218270_at	0.332	9.273	3.254	5.253e-03	0.285	-2.056	MRPL24	mitochondrial ribosomal protein L24	1	-154973717	NM_024540	79590	1q21-q22	Hs.418233	9	structural constituent of ribosome intracellular mitochondrion ribosome translation
234317_s_at	0.457	5.728	3.254	5.256e-03	0.285	-2.056	STOX2	storkhead box 2	4	185063502	AL390216	56977	4q35.1	Hs.21958 Hs.696657	3
201599_at	-0.742	9.166	-3.251	5.290e-03	0.287	-2.062	OAT	ornithine aminotransferase (gyrate atrophy)	10	-126075861	NM_000274	4942	10q26	Hs.523332	28	ornithine-oxo-acid transaminase activity protein binding cytoplasm mitochondrion mitochondrial matrix visual perception transferase activity pyridoxal phosphate binding	Arginine and proline metabolism Metabolic pathways
203465_at	-0.693	8.070	-3.250	5.300e-03	0.287	-2.063	MRPL19	mitochondrial ribosomal protein L19	2	75727416	NM_014763	9801	2q11.1-q11.2	Hs.44024	11	structural constituent of ribosome intracellular nucleus mitochondrion ribosome translation nuclear membrane
1570242_x_at	-0.267	6.366	-3.249	5.309e-03	0.287	-2.065	SPATA21	spermatogenesis associated 21	1	-16597724	BC022039	374955	1p36.13	Hs.705501	1	calcium ion binding
206695_x_at	0.621	3.798	3.249	5.315e-03	0.287	-2.066	ZNF43	zinc finger protein 43	19	-21779591	NM_003423	7594	19p13.1-p12	Hs.534365	13	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201392_s_at	0.522	8.226	3.247	5.331e-03	0.288	-2.069	IGF2R	insulin-like growth factor 2 receptor	6	160310120	BG031974	3482	6q26	Hs.487062	101	glycoprotein binding receptor activity insulin-like growth factor receptor activity transporter activity insulin-like growth factor binding mannose binding membrane fraction nucleus nuclear envelope lumen cytoplasm lysosome endosome Golgi apparatus integral to plasma membrane transport receptor-mediated endocytosis signal transduction membrane trans-Golgi network transport vesicle	Lysosome
232488_at	0.462	6.953	3.247	5.337e-03	0.288	-2.070	AGXT2L2	alanine-glyoxylate aminotransferase 2-like 2	5	-177568146	AK023470	85007	5q35.3	Hs.248746	4	mitochondrion transaminase activity transferase activity pyridoxal phosphate binding
238117_at	0.493	3.644	3.246	5.349e-03	0.288	-2.072	PPOX	protoporphyrinogen oxidase	1	159402804	AW615133	5498	1q22	Hs.517373	32	oxygen-dependent protoporphyrinogen oxidase activity oxygen-dependent protoporphyrinogen oxidase activity mitochondrion mitochondrial intermembrane space heme biosynthetic process electron carrier activity membrane oxidoreductase activity intrinsic to mitochondrial inner membrane FAD binding oxidation reduction	Porphyrin and chlorophyll metabolism Metabolic pathways
228909_at	0.294	4.595	3.245	5.354e-03	0.288	-2.073	LOC642852	hypothetical LOC642852	21	45532394	AW131553	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
208985_s_at	-0.574	9.651	-3.244	5.362e-03	0.288	-2.074	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	BC002719	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
209563_x_at	-0.358	11.120	-3.243	5.383e-03	0.289	-2.077	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	BC000454	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
202204_s_at	-0.374	7.366	-3.240	5.410e-03	0.290	-2.082	AMFR	autocrine motility factor receptor	16	-54952864	AF124145	267	16q21	Hs.295137	33	protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization
1555630_a_at	0.361	6.032	3.240	5.411e-03	0.290	-2.082	RAB34	RAB34, member RAS oncogene family	17	-24065425, -24065425, -24065425	AF327350	83871	17q11.2	Hs.301853	16	nucleotide binding ruffle GTPase activity GTP binding cytoplasm early endosome Golgi apparatus endocytosis small GTPase mediated signal transduction protein transport guanyl nucleotide binding
235070_at	-0.370	8.267	-3.238	5.433e-03	0.290	-2.086	A2BP1	ataxin 2-binding protein 1	16	6009132, 6763810, 7322751	AL133898	54715	16p13.3	Hs.459842	22	nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport
206492_at	0.632	5.547	3.237	5.443e-03	0.291	-2.087	FHIT	fragile histidine triad gene	3	-59710075	NM_002012	2272	3p14.2	Hs.715588 Hs.715597	164	magnesium ion binding protein binding cytoplasm DNA replication nucleotide metabolic process hydrolase activity manganese ion binding bis(5'-adenosyl)-triphosphatase activity	Purine metabolism Small cell lung cancer Non-small cell lung cancer
208936_x_at	0.370	6.008	3.235	5.468e-03	0.291	-2.092	LGALS8	lectin, galactoside-binding, soluble, 8	1	234748187, 234753361, 234753699	AF074000	3964	1q42-q43	Hs.4082 Hs.708114	29	sugar binding extracellular space cytoplasm
229327_s_at	-0.802	7.139	-3.233	5.492e-03	0.292	-2.095	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	16	-78185246	BE674528	4094	16q22-q23	Hs.134859	37	chromatin cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of chondrocyte differentiation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cell development lens fiber cell differentiation
235166_at	-0.269	4.133	-3.232	5.500e-03	0.292	-2.097	ZNF148	zinc finger protein 148	3	-126427202	T08836	7707	3q21	Hs.592591	34	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex nucleolus Golgi apparatus cellular defense response gamete generation zinc ion binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
1554568_at	0.261	2.795	3.231	5.511e-03	0.293	-2.098	DYNLRB1	dynein, light chain, roadblock-type 1	20	32567864	BC007223	83658	20q11.21	Hs.593920	17	microtubule motor activity protein binding cytoplasm cytoplasmic dynein complex microtubule microtubule-based movement visual behavior
205726_at	-0.660	6.840	-3.230	5.523e-03	0.293	-2.101	DIAPH2	diaphanous homolog 2 (Drosophila)	X	95826317, 95826317	NM_006729	1730	Xq21.33	Hs.226483 Hs.716101	14	cytokinesis actin binding receptor binding cytoplasm early endosome Golgi apparatus cytosol multicellular organismal development cellular component organization Rho GTPase binding actin cytoskeleton organization cell differentiation oogenesis	Regulation of actin cytoskeleton
204346_s_at	-0.398	6.119	-3.228	5.548e-03	0.294	-2.105	RASSF1	Ras association (RalGDS/AF-6) domain family member 1	3	-50342220, -50342220, -50342220	NM_007182	11186	3p21.3	Hs.476270	170	nucleus cytoplasm centrosome spindle microtubule cell cycle cell cycle arrest intracellular signaling cascade Ras protein signal transduction zinc ion binding diacylglycerol binding identical protein binding metal ion binding	Pathways in cancer Bladder cancer Non-small cell lung cancer
226616_s_at	-0.504	10.644	-3.224	5.596e-03	0.295	-2.112	NDUFV3	NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa	21	43186446	NM_021075	4731	21q22.3	Hs.473937	16	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1553954_at	0.660	5.747	3.224	5.597e-03	0.295	-2.112	ALG14	asparagine-linked glycosylation 14 homolog (S. cerevisiae)	1	-95220866	BU682208	199857	1p21.3	Hs.408927	5	endoplasmic reticulum membrane integral to membrane	N-Glycan biosynthesis Metabolic pathways
208753_s_at	-0.459	8.160	-3.223	5.601e-03	0.295	-2.113	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	BC002387	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
219017_at	0.493	4.987	3.223	5.610e-03	0.295	-2.115	ETNK1	ethanolamine kinase 1	12	22669342, 22669342	NM_018638	55500	12p12.1	Hs.29464	4	nucleotide binding ethanolamine kinase activity ATP binding cytoplasm phosphatidylethanolamine biosynthetic process transferase activity	Glycerophospholipid metabolism Metabolic pathways
1555789_s_at	-0.356	6.167	-3.222	5.618e-03	0.295	-2.116	PHF23	PHD finger protein 23	17	-7079070	AY099328	79142	17p13.1	Hs.647432	4	protein binding zinc ion binding metal ion binding
213373_s_at	0.514	4.414	3.220	5.640e-03	0.295	-2.119	CASP8	caspase 8, apoptosis-related cysteine peptidase	2	201806410, 201806410, 201830998, 201833467	BF439983	841	2q33-q34	Hs.599762	362	cysteine-type endopeptidase activity nucleus cytoplasm mitochondrion cytosol cytoskeleton peptidase activity induction of apoptosis by extracellular signals induction of apoptosis by extracellular signals activation of pro-apoptotic gene products death-inducing signaling complex response to tumor necrosis factor identical protein binding regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade proteolysis involved in cellular protein catabolic process	p53 signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Alzheimer's disease Huntington's disease Pathways in cancer
214844_s_at	-0.541	9.310	-3.220	5.641e-03	0.295	-2.119	DOK5	docking protein 5	20	52525672	AL050069	55816	20q13.2	Hs.656582	10	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
228696_at	0.267	4.077	3.219	5.655e-03	0.295	-2.122	SLC45A3	solute carrier family 45, member 3	1	-203893603	AA631143	85414	1q32.1	Hs.278695	9	transport membrane integral to membrane
207394_at	0.442	3.848	3.216	5.688e-03	0.296	-2.127	ZNF137	zinc finger protein 137	19	57791748	NM_003438	7696	19q13.4	Hs.373648	3
214121_x_at	-0.591	9.173	-3.216	5.691e-03	0.296	-2.127	PDLIM7	PDZ and LIM domain 7 (enigma)	5	-176849852, -176843000	AA086229	9260	5q35.3	Hs.533040	22	ossification protein binding cytoplasm cytoskeleton receptor-mediated endocytosis multicellular organismal development zinc ion binding cell differentiation metal ion binding
235695_at	0.297	4.629	3.210	5.762e-03	0.299	-2.139	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	2	98427752, 98427752	AI051236	3631	2q11.2	Hs.469386	16	signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
203920_at	0.419	5.158	3.207	5.787e-03	0.300	-2.142	NR1H3	nuclear receptor subfamily 1, group H, member 3	11	47227024, 47236072	NM_005693	10062	11p11.2	Hs.438863 Hs.513522	94	transcription factor activity steroid hormone receptor activity transcription coactivator activity thyroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding positive regulation of specific transcription from RNA polymerase II promoter negative regulation of foam cell differentiation positive regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux negative regulation of cholesterol storage positive regulation of cellular protein metabolic process negative regulation of lipid transport sequence-specific DNA binding positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of pinocytosis positive regulation of lipoprotein lipase activity	PPAR signaling pathway
206175_x_at	0.351	4.863	3.207	5.791e-03	0.300	-2.143	ZNF222	zinc finger protein 222	19	49221333	NM_013360	7673	19q13.2	Hs.279840	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231908_at	0.320	4.401	3.207	5.793e-03	0.300	-2.143	ZDHHC18	zinc finger, DHHC-type containing 18	1	27025787	AL034380	84243	1p36.11	Hs.523710	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
222128_at	0.422	4.525	3.207	5.798e-03	0.300	-2.144	NSUN6	NOL1/NOP2/Sun domain family, member 6	10	-18874269	U80764	221078	10p12.31	Hs.396175	4	RNA binding methyltransferase activity transferase activity
224352_s_at	-0.447	11.148	-3.206	5.804e-03	0.300	-2.145	CFL2	cofilin 2 (muscle)	14	-34249338, -34249338, -34249338	AF134802	1073	14q12	Hs.180141	20	actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
218403_at	-0.330	9.088	-3.205	5.813e-03	0.300	-2.146	TRIAP1	TP53 regulated inhibitor of apoptosis 1	12	-119366146	NM_016399	51499	12q24.31	Hs.69499	7	protein binding cytoplasm mitochondrion apoptosis anti-apoptosis DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest caspase inhibitor activity perinuclear region of cytoplasm
227135_at	-0.281	5.638	-3.205	5.813e-03	0.300	-2.146	NAAA	N-acylethanolamine acid amidase	4	-77053832, -77050831	AI436803	27163	4q21.1	Hs.437365	12	molecular_function cellular_component cytoplasm lysosome lipid metabolic process biological_process hydrolase activity
208763_s_at	-0.482	9.335	-3.204	5.829e-03	0.300	-2.149	TSC22D3	TSC22 domain family, member 3	X	-106843107, -106843107, -106843107	AL110191	1831	Xq22.3	Hs.716410	24	transcription factor activity regulation of transcription, DNA-dependent
242564_at	0.298	3.681	3.204	5.832e-03	0.300	-2.149	ZNF814	zinc finger protein 814	19	-63072558	AI703142	730051	19q13.43	Hs.634143 Hs.669024 Hs.719319	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235497_at	-0.584	7.209	-3.202	5.856e-03	0.300	-2.153	LOC643837	hypothetical LOC643837	1	752926	AL079648	643837	1p36.33	Hs.133183	2
226664_at	0.287	6.004	3.201	5.860e-03	0.300	-2.154	TBC1D20	TBC1 domain family, member 20	20	-364123	AL121747	128637	20p13	Hs.590876	8	GTPase activator activity Rab GTPase activator activity intracellular membrane integral to membrane regulation of Rab GTPase activity interspecies interaction between organisms
238577_s_at	0.350	2.850	3.201	5.863e-03	0.300	-2.154	TSHZ2	teashirt zinc finger homeobox 2	20	51022283	AA628481	128553	20q13.2	Hs.271605 Hs.473117 Hs.649877	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding
204479_at	0.368	6.163	3.201	5.866e-03	0.300	-2.155	OSTF1	osteoclast stimulating factor 1	9	76893217	NM_012383	26578	9q13-q21.2	Hs.494192	17	ossification intracellular cytoplasm signal transduction identical protein binding
223113_at	0.400	6.164	3.201	5.868e-03	0.300	-2.155	TMEM138	transmembrane protein 138	11	60886431	AF151030	51524	11q12.2	Hs.406530	3	membrane integral to membrane
227396_at	0.633	5.515	3.199	5.885e-03	0.300	-2.157	PTPRJ	protein tyrosine phosphatase, receptor type, J	11	47958685, 47958685	AI631833	5795	11p11.2	Hs.318547	36	transmembrane receptor protein tyrosine phosphatase activity protein binding nucleus plasma membrane integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling hydrolase activity cell junction	Adherens junction
209681_at	-1.258	8.790	-3.199	5.889e-03	0.300	-2.158	SLC19A2	solute carrier family 19 (thiamine transporter), member 2	1	-167699772	AF153330	10560	1q23.3	Hs.30246	32	folic acid binding cytoplasm plasma membrane transport folic acid transporter activity reduced folate carrier activity thiamin transmembrane transporter activity thiamin transport integral to membrane thiamin and derivative metabolic process
241172_at	0.251	3.852	3.199	5.890e-03	0.300	-2.158	GRIA2	glutamate receptor, ionotropic, AMPA 2	4	158361185, 158361269	AI939470	2891	4q32-q33	Hs.32763	48	regulation of receptor recycling receptor activity alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity protein binding plasma membrane ion transport signal transduction response to lithium ion postsynaptic density kainate selective glutamate receptor activity integral to membrane cell junction PDZ domain binding growth cone synaptic vesicle membrane receptor internalization asymmetric synapse presynaptic membrane cell soma dendritic spine dendritic shaft protein complex establishment of protein localization postsynaptic membrane positive regulation of synaptic transmission regulation of synaptic transmission, glutamatergic	Neuroactive ligand-receptor interaction Long-term potentiation Long-term depression Amyotrophic lateral sclerosis (ALS)
223125_s_at	-0.409	9.410	-3.199	5.891e-03	0.300	-2.158	C1orf21	chromosome 1 open reading frame 21	1	182622772	AL563236	81563	1q25	Hs.497159 Hs.719188	8
201258_at	-0.477	11.844	-3.198	5.900e-03	0.300	-2.160	RPS16	ribosomal protein S16	19	-44615686	NM_001020	6217	19q13.1	Hs.397609	24	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
225466_at	-0.381	7.832	-3.198	5.901e-03	0.300	-2.160	PATL1	protein associated with topoisomerase II homolog 1 (yeast)	11	-59160767	BG291961	219988	11q12.1	Hs.591960	8	cytoplasmic mRNA processing body cytoplasm	RNA degradation
213899_at	0.491	6.305	3.197	5.907e-03	0.300	-2.161	METAP2	methionyl aminopeptidase 2	12	94391952	AI743685	10988	12q22	Hs.444986	35	aminopeptidase activity cytoplasm proteolysis peptidase activity metalloexopeptidase activity cellular process protein processing peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding
210102_at	0.420	4.548	3.193	5.958e-03	0.302	-2.168	VWA5A	von Willebrand factor A domain containing 5A	11	123491320, 123491320	BC001234	4013	11q23	Hs.152944	5
202479_s_at	-0.475	5.774	-3.192	5.969e-03	0.302	-2.170	TRIB2	tribbles homolog 2 (Drosophila)	2	12774448, 12774448	BC002637	28951	2p24.3	Hs.467751	16	nucleotide binding protein kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoskeleton protein amino acid phosphorylation regulation of MAP kinase activity
211938_at	-0.291	10.524	-3.192	5.970e-03	0.302	-2.170	EIF4B	eukaryotic translation initiation factor 4B	12	51686328	BF247371	1975	12q13.13	Hs.648394 Hs.702041	23	nucleotide binding RNA binding translation initiation factor activity cytosol translation regulation of translational initiation eukaryotic translation initiation factor 4F complex	mTOR signaling pathway
226017_at	0.392	6.648	3.192	5.973e-03	0.302	-2.171	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	3	32408166	AI708432	112616	3p22.3	Hs.440494	4	cytokine activity extracellular space chemotaxis membrane integral to membrane
221231_s_at	-0.302	4.221	-3.192	5.977e-03	0.302	-2.171	C14orf102	chromosome 14 open reading frame 102	14	-89814150	NM_017970	55051	14q32.11	Hs.528131	4	protein binding
227259_at	0.405	5.147	3.188	6.024e-03	0.304	-2.178	CD47	CD47 molecule	3	-109244630	BF439618	961	3q13.1-q13.2	Hs.446414	68	protein binding plasma membrane plasma membrane integral to plasma membrane cell adhesion integrin-mediated signaling pathway positive regulation of cell proliferation positive regulation of cell-cell adhesion positive regulation of T cell activation thrombospondin receptor activity	ECM-receptor interaction
1555759_a_at	0.344	5.788	3.188	6.026e-03	0.304	-2.179	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	AF043341	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
218488_at	0.222	9.280	3.186	6.045e-03	0.305	-2.181	EIF2B3	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	1	-45089036	NM_020365	8891	1p34.1	Hs.533549	25	translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm eukaryotic translation initiation factor 2B complex translational initiation biosynthetic process response to heat response to heat response to glucose stimulus oligodendrocyte development transferase activity nucleotidyltransferase activity negative regulation of translational initiation in response to stress response to peptide hormone stimulus cellular response to stimulus
224677_x_at	-0.291	8.682	-3.185	6.057e-03	0.305	-2.183	C11orf31	chromosome 11 open reading frame 31	11	57265297	AV729234	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
1569171_a_at	0.286	4.857	3.184	6.071e-03	0.305	-2.185	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	BC034416	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
1552732_at	-1.144	10.048	-3.184	6.072e-03	0.305	-2.185	ABRA	actin-binding Rho activating protein	8	-107840886	AL832152	137735	8q23.1	Hs.374668	12	protein import into nucleus, translocation transcription coactivator activity actin binding cytoplasm plasma membrane protein transport actin cytoskeleton sarcomere positive regulation of Rho protein signal transduction positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription factor activity intracellular protein transmembrane transport
203921_at	0.295	4.537	3.182	6.099e-03	0.305	-2.190	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	3	144321357	NM_004267	9435	3q24	Hs.8786	19	N-acetylglucosamine 6-O-sulfotransferase activity Golgi apparatus trans-Golgi network carbohydrate metabolic process N-acetylglucosamine metabolic process sulfur metabolic process inflammatory response multicellular organismal development membrane integral to membrane transferase activity intrinsic to Golgi membrane	Keratan sulfate biosynthesis Metabolic pathways
200961_at	-0.408	8.180	-3.182	6.103e-03	0.305	-2.190	SEPHS2	selenophosphate synthetase 2	16	-30362452	NM_012248	22928	16p11.2	Hs.718460	7	nucleotide binding selenide, water dikinase activity ATP binding cellular_component selenium binding selenocysteine biosynthetic process transferase activity	Selenoamino acid metabolism Metabolic pathways
214294_at	-0.273	5.290	-3.182	6.103e-03	0.305	-2.190	KIAA0485	hypothetical LOC57235			AI122905	57235		Hs.604754	1
218786_at	-0.395	6.181	-3.181	6.106e-03	0.305	-2.190	NT5DC3	5'-nucleotidase domain containing 3	12	-102690210	NM_016575	51559	12q22-q23.1	Hs.48428	4	magnesium ion binding hydrolase activity
205472_s_at	0.562	4.213	3.181	6.116e-03	0.305	-2.192	DACH1	dachshund homolog 1 (Drosophila)	13	-70910098	NM_004392	1602	13q22	Hs.129452	24	nucleotide binding transcription factor activity protein binding nucleus transcription factor complex cytoplasm multicellular organismal development regulation of transcription
228316_at	0.423	4.186	3.180	6.119e-03	0.305	-2.192	C2orf63	chromosome 2 open reading frame 63	2	-55253187, -55253187	AA905470	130162	2p16.1	Hs.347014	4	binding
204294_at	0.350	7.196	3.180	6.120e-03	0.305	-2.193	AMT	aminomethyltransferase	3	-49429214	NM_000481	275	3p21.2-p21.1	Hs.102	17	aminomethyltransferase activity cytoplasm mitochondrion glycine catabolic process transaminase activity transferase activity	Glycine, serine and threonine metabolism One carbon pool by folate Nitrogen metabolism Metabolic pathways
204589_at	0.530	7.466	3.180	6.122e-03	0.305	-2.193	NUAK1	NUAK family, SNF1-like kinase, 1	12	-104981254	NM_014840	9891	12q23.3	Hs.719171	13	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
217821_s_at	-0.390	5.997	-3.180	6.125e-03	0.305	-2.193	WBP11	WW domain binding protein 11	12	-14830678	AF118023	51729	12p12.3	Hs.655138	13	single-stranded DNA binding protein binding nucleus cytoplasm rRNA processing mRNA processing RNA splicing protein phosphatase type 1 regulator activity nuclear speck
228790_at	-0.592	6.461	-3.180	6.128e-03	0.305	-2.194	FAM110B	family with sequence similarity 110, member B	8	59069666	AW264082	90362	8q12.1	Hs.154652	7	cytoplasm mitochondrion centrosome
1554679_a_at	-1.411	8.658	-3.177	6.155e-03	0.306	-2.198	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	AF317417	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
212409_s_at	-0.655	5.992	-3.177	6.159e-03	0.306	-2.198	TOR1AIP1	torsin A interacting protein 1	1	178118042	AK021613	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
226617_at	-0.586	8.348	-3.175	6.182e-03	0.306	-2.202	ARL5A	ADP-ribosylation factor-like 5A	2	-152365725	AW291264	26225	2q23.3	Hs.470233	6	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
201531_at	-0.539	7.413	-3.175	6.183e-03	0.306	-2.202	ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	19	44589326	NM_003407	7538	19q13.1	Hs.534052 Hs.707878	62	nuclear-transcribed mRNA poly(A) tail shortening DNA binding single-stranded RNA binding mRNA binding protein binding nucleus cytoplasm cytosol mRNA catabolic process protein kinase cascade zinc ion binding AU-rich element binding regulation of mRNA stability negative regulation of myeloid cell differentiation metal ion binding negative regulation of inflammatory response RNA destabilization
209545_s_at	0.285	5.602	3.174	6.204e-03	0.306	-2.205	RIPK2	receptor-interacting serine-threonine kinase 2	8	90839109	AF064824	8767	8q21	Hs.103755	52	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity signal transducer activity protein binding ATP binding intracellular cytoplasm cytosol protein amino acid phosphorylation inflammatory response signal transduction transferase activity LIM domain binding positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 2 signaling pathway T cell proliferation positive regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JNK cascade CARD domain binding defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of ERK1 and ERK2 cascade	Neurotrophin signaling pathway
206182_at	0.381	5.196	3.174	6.205e-03	0.306	-2.205	ZNF134	zinc finger protein 134	19	62817641	NM_003435	7693	19q13.4	Hs.469694	2	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208407_s_at	0.397	6.604	3.172	6.219e-03	0.307	-2.207	CTNND1	catenin (cadherin-associated protein), delta 1	11	57285809	NM_001331	1500	11q11	Hs.166011	99	protein binding nucleus cytoplasm plasma membrane Wnt receptor signaling pathway cell-cell adhesion cadherin binding regulation of transcription	Adherens junction Leukocyte transendothelial migration
238697_at	0.352	3.047	3.172	6.228e-03	0.307	-2.208	NCRNA00086	non-protein coding RNA 86	X	134383533	AA565509	399668	Xq26.3	Hs.374414	3
212552_at	0.337	6.716	3.170	6.250e-03	0.307	-2.211	HPCAL1	hippocalcin-like 1	2	10360490, 10361276	BE617588	3241	2p25.1	Hs.467696 Hs.580427	20	calcium ion binding protein binding
205160_at	0.416	6.679	3.169	6.265e-03	0.308	-2.214	PEX11A	peroxisomal biogenesis factor 11 alpha	15	-88027290	AL360141	8800	15q26.1	Hs.31034	9	peroxisome peroxisomal membrane integral to peroxisomal membrane signal transduction membrane integral to membrane peroxisome fission
210321_at	0.393	4.655	3.169	6.270e-03	0.308	-2.214	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	14	-24145532	M36118	2999	14q11.2	Hs.348264	17	serine-type endopeptidase activity cytoplasm proteolysis apoptosis peptidase activity cytolysis
225314_at	0.527	5.913	3.168	6.272e-03	0.308	-2.214	OCIAD2	OCIA domain containing 2	4	-48582161	BG291649	132299	4p11	Hs.95835	2	mitochondrion mitochondrial inner membrane endosome
212681_at	0.997	4.830	3.168	6.281e-03	0.308	-2.216	EPB41L3	erythrocyte membrane protein band 4.1-like 3	18	-5382387	AI770004	23136	18p11.32	Hs.213394	39	actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization	Tight junction
202341_s_at	0.321	5.699	3.167	6.287e-03	0.308	-2.217	TRIM2	tripartite motif-containing 2	4	154293719, 154345047	AA149745	23321	4q31.3	Hs.435711	6	protein binding intracellular cytoplasm biological_process zinc ion binding metal ion binding
202467_s_at	-0.498	9.905	-3.166	6.298e-03	0.308	-2.218	COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	15	-47204762	NM_004236	9318	15q21.2	Hs.369614	37	signal transducer activity protein binding protein binding nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter signal transduction signalosome
223461_at	0.549	6.889	3.165	6.317e-03	0.308	-2.221	TBC1D7	TBC1 domain family, member 7	6	-13413164	AF151073	51256	6p24.1	Hs.484678	9	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
203803_at	-0.860	7.593	-3.163	6.341e-03	0.309	-2.224	PCYOX1	prenylcysteine oxidase 1	2	70338734	N45309	51449	2p13.3	Hs.567502	13	prenylcysteine oxidase activity binding lysosome oxidoreductase activity prenylated protein catabolic process prenylcysteine catabolic process very-low-density lipoprotein particle oxidation reduction
235686_at	0.276	4.108	3.163	6.342e-03	0.309	-2.224	C2orf60	chromosome 2 open reading frame 60	2	-200501878	BF108661	129450	2q33.1	Hs.204619	3
204999_s_at	1.299	5.575	3.163	6.347e-03	0.309	-2.225	ATF5	activating transcription factor 5	19	55123785	BC005174	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
211450_s_at	-0.461	4.469	-3.161	6.368e-03	0.309	-2.228	MSH6	mutS homolog 6 (E. coli)	2	47863724	D89646	2956	2p16	Hs.445052	162	nucleotide binding magnesium ion binding four-way junction DNA binding meiotic mismatch repair nuclear chromatin chromatin binding damaged DNA binding protein binding ATP binding nucleus response to DNA damage stimulus determination of adult lifespan DNA damage response, signal transduction resulting in induction of apoptosis response to UV somatic hypermutation of immunoglobulin genes somatic recombination of immunoglobulin gene segments ATPase activity guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding MutSalpha complex oxidized purine DNA binding MutLalpha complex binding protein homodimerization activity ADP binding maintenance of DNA repeat elements isotype switching negative regulation of DNA recombination positive regulation of helicase activity	Mismatch repair Pathways in cancer Colorectal cancer
222762_x_at	0.431	6.680	3.160	6.387e-03	0.310	-2.231	LIMD1	LIM domains containing 1	3	45611326	AU144259	8994	3p21.3	Hs.193370 Hs.621057	14	protein binding regulation of transcription, DNA-dependent signal transduction multicellular organismal development zinc ion binding metal ion binding
203870_at	0.528	7.329	3.159	6.390e-03	0.310	-2.231	USP46	ubiquitin specific peptidase 46	4	-53151885, -53151885	BE856374	64854	4q12	Hs.7966	10	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding ubiquitin-dependent protein catabolic process behavior peptidase activity cysteine-type peptidase activity protein deubiquitination regulation of synaptic transmission, GABAergic
213592_at	0.545	6.462	3.159	6.395e-03	0.310	-2.232	APLNR	apelin receptor	11	-56757629	X89271	187	11q12	Hs.438311	29	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway	Neuroactive ligand-receptor interaction
226515_at	-0.386	8.030	-3.157	6.421e-03	0.311	-2.236	CCDC127	coiled-coil domain containing 127	5	-257874	AL577758	133957	5p15.33	Hs.294145	4
213035_at	-0.644	7.921	-3.156	6.438e-03	0.311	-2.238	ANKRD28	ankyrin repeat domain 28	3	-15683747	AI081194	23243	3p25.1	Hs.335239	10	protein binding nucleus nucleoplasm
224932_at	0.454	11.130	3.156	6.440e-03	0.311	-2.238	CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10	22	-22438020	AI814909	400916	22q11.23	Hs.66915	2	mitochondrion
213733_at	0.296	4.788	3.155	6.447e-03	0.311	-2.239	MYO1F	myosin IF	19	-8491996	BF740152	4542	19p13.3-p13.2	Hs.465818	11	nucleotide binding motor activity actin binding calmodulin binding ATP binding negative regulation of cell adhesion biological_process unconventional myosin complex positive regulation of cell migration cortical actin cytoskeleton filamentous actin regulation of actin cytoskeleton organization neutrophil degranulation regulation of innate immune response defense response to Gram-positive bacterium
219514_at	-0.409	5.030	-3.153	6.471e-03	0.311	-2.243	ANGPTL2	angiopoietin-like 2	9	-128889448	NM_012098	23452	9q34	Hs.653262	11	receptor binding extracellular region extracellular space signal transduction multicellular organismal development
218178_s_at	-0.533	8.778	-3.152	6.490e-03	0.312	-2.245	CHMP1B	chromatin modifying protein 1B	18	11841388	NM_020412	57132	18p11.21	Hs.656244	16	cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division	Endocytosis
203721_s_at	-0.637	7.769	-3.151	6.503e-03	0.312	-2.247	UTP18	UTP18, small subunit (SSU) processome component, homolog (yeast)	17	46692895	NM_016001	51096	17q21.33	Hs.709327	11	nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing
204185_x_at	-0.462	9.597	-3.151	6.503e-03	0.312	-2.247	PPID	peptidylprolyl isomerase D	4	-159849728	NM_005038	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
201886_at	0.247	7.279	3.150	6.508e-03	0.312	-2.248	DCAF11	DDB1 and CUL4 associated factor 11	14	23653745, 23653825, 23654331, 23654333	NM_025230	80344	14q11.2	Hs.525251	9	protein binding
218300_at	0.288	7.164	3.150	6.509e-03	0.312	-2.248	C16orf53	chromosome 16 open reading frame 53	16	29735028	NM_024516	79447	16p11.2	Hs.702841	7
201811_x_at	0.834	8.105	3.150	6.517e-03	0.312	-2.249	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	3	-15271360, -15271360	NM_004844	9467	3p24.3	Hs.257761 Hs.719150	11	protein kinase inhibitor activity protein binding cytoplasm mitochondrion intracellular signaling cascade SH3 domain binding
231837_at	-0.626	7.163	-3.148	6.538e-03	0.312	-2.252	USP28	ubiquitin specific peptidase 28	11	-113173806	AB040948	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
213238_at	0.357	5.264	3.148	6.539e-03	0.312	-2.252	ATP10D	ATPase, class V, type 10D	4	47182166	AI478147	57205	4p12	Hs.437241	4	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
223093_at	-0.476	6.531	-3.147	6.550e-03	0.312	-2.253	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	T99215	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
236813_at	0.404	5.600	3.147	6.556e-03	0.312	-2.254	MORN4	MORN repeat containing 4	10	-99364299, -99364299	N21659	118812	10q24.2	Hs.217409	6
218352_at	0.531	5.266	3.145	6.584e-03	0.313	-2.258	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	13	-49004082	NM_018191	55213	13q14	Hs.508021	11	protein binding nucleus cytoplasm cell cycle chromatin modification regulation of transcription
203161_s_at	-0.301	4.074	-3.143	6.606e-03	0.314	-2.261	RNF8	ring finger protein 8	6	37429725	NM_003958	9025	6p21.3	Hs.485278	24	ubiquitin ligase complex chromatin binding ubiquitin-protein ligase activity nucleus chromosome double-strand break repair response to DNA damage stimulus cell cycle mitosis zinc ion binding response to ionizing radiation protein ubiquitination chromatin modification ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process histone H2A ubiquitination histone H2B ubiquitination histone binding positive regulation of DNA repair metal ion binding cell division
230660_at	0.288	4.242	3.143	6.613e-03	0.314	-2.262	SERTAD4	SERTA domain containing 4	1	208472817	AU146709	56256	1q32.1-q41	Hs.600545	2
240381_at	0.317	5.864	3.141	6.629e-03	0.314	-2.264	ZBED5	zinc finger, BED-type containing 5	11	-10830829	AA813103	58486	11p15.3	Hs.655066	5	DNA binding zinc ion binding metal ion binding
203238_s_at	0.355	5.554	3.141	6.630e-03	0.314	-2.264	NOTCH3	Notch homolog 3 (Drosophila)	19	-15131443	NM_000435	4854	19p13.2-p13.1	Hs.8546	96	receptor activity calcium ion binding protein binding nucleus plasma membrane Notch signaling pathway multicellular organismal development integral to membrane forebrain development regulation of transcription negative regulation of neuron differentiation neuron fate commitment regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
238614_x_at	0.288	2.660	3.140	6.651e-03	0.314	-2.267	ZNF430	zinc finger protein 430	19	20995336	AW954842	80264	19p12	Hs.466289	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
233801_s_at	0.367	5.443	3.140	6.652e-03	0.314	-2.267	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	15	45797977, 45797977	AK022747	80031	15q21.1	Hs.511265	8	receptor activity cytoplasm plasma membrane multicellular organismal development nervous system development integral to membrane cell differentiation	Axon guidance
204950_at	0.438	6.268	3.139	6.665e-03	0.314	-2.269	CARD8	caspase recruitment domain family, member 8	19	-53403154	NM_014959	22900	19q13.33	Hs.446146 Hs.655940	23	protein binding intracellular nucleus cytoplasm caspase activator activity NACHT domain binding protein homodimerization activity regulation of apoptosis negative regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of caspase activity positive regulation of interleukin-1 beta secretion
224378_x_at	0.328	7.995	3.138	6.673e-03	0.314	-2.270	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	AF276658	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
226916_x_at	-0.280	6.304	-3.138	6.673e-03	0.314	-2.270	DPP9	dipeptidyl-peptidase 9	19	-4626243	AW190431	91039	19p13.3	Hs.515081	14	aminopeptidase activity cytoplasm cytosol proteolysis peptidase activity serine-type peptidase activity membrane
216489_at	0.359	3.718	3.137	6.684e-03	0.314	-2.272	TRPM3	transient receptor potential cation channel, subfamily M, member 3	9	-72588597, -72339785, -72339785	AB046836	80036	9q21.12	Hs.47288	19	calcium channel activity calcium ion binding cation transport calcium ion transport membrane integral to membrane
235180_at	-0.232	2.966	-3.137	6.694e-03	0.314	-2.273	STYX	serine/threonine/tyrosine interacting protein	14	52266632	AI492892	6815		Hs.364980	8	protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
238944_at	0.560	6.368	3.137	6.694e-03	0.314	-2.273	ZNF404	zinc finger protein 404	19	-49068354	AI393706	342908	19q13.31	Hs.76561	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226089_at	0.414	4.845	3.136	6.698e-03	0.314	-2.273	RABL3	RAB, member of RAS oncogene family-like 3	3	-121888217	AI742028	285282	3q13.33	Hs.444360	1	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
224839_s_at	0.738	7.443	3.136	6.699e-03	0.314	-2.274	GPT2	glutamic pyruvate transaminase (alanine aminotransferase) 2	16	45475808, 45476602	BG328998	84706	16q12.1	Hs.460693	9	L-alanine:2-oxoglutarate aminotransferase activity transaminase activity biosynthetic process pyridoxal phosphate binding	Alanine, aspartate and glutamate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
210967_x_at	-0.288	9.549	-3.136	6.700e-03	0.314	-2.274	CACNB1	calcium channel, voltage-dependent, beta 1 subunit	17	-34586914, -34583234	M92301	782	17q21-q22	Hs.635	18	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
238813_at	0.339	4.336	3.136	6.702e-03	0.314	-2.274	ALAS2	aminolevulinate, delta-, synthase 2	X	-55052213	AI910842	212	Xp11.21	Hs.522666 Hs.555936	29	response to hypoxia 5-aminolevulinate synthase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix porphyrin metabolic process heme biosynthetic process heme biosynthetic process cellular iron ion homeostasis acyltransferase activity glycine binding transferase activity, transferring nitrogenous groups pyridoxal phosphate binding erythrocyte differentiation erythrocyte differentiation oxygen homeostasis tetrapyrrole biosynthetic process hemoglobin biosynthetic process coenzyme binding	Glycine, serine and threonine metabolism Porphyrin and chlorophyll metabolism Metabolic pathways
244861_at	0.268	6.374	3.136	6.705e-03	0.314	-2.274	ZNF527	zinc finger protein 527	19	42553898	AI679883	84503	19q13.1	Hs.590940	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
230871_at	0.383	5.661	3.135	6.720e-03	0.314	-2.276	DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	3	47819402	H67762	22907	3p21.31	Hs.517948	7	nucleotide binding RNA binding helicase activity ATP binding cytoplasm mitochondrion ATP-dependent helicase activity hydrolase activity mitochondrial nucleoid
209249_s_at	-0.324	11.307	-3.134	6.728e-03	0.314	-2.277	GHITM	growth hormone inducible transmembrane protein	10	85889164	AF131820	27069	10q23.1	Hs.352656	15	molecular_function biological_process membrane integral to membrane
1553062_at	0.487	5.203	3.134	6.733e-03	0.314	-2.278	MOGAT1	monoacylglycerol O-acyltransferase 1	2	223244700	NM_058165	116255	2q36.1	Hs.344090	4	2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity membrane fraction endoplasmic reticulum glycerol metabolic process diacylglycerol biosynthetic process acyltransferase activity lipid biosynthetic process membrane integral to membrane transferase activity
239004_at	0.214	5.936	3.132	6.757e-03	0.315	-2.281	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	AI041019	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
200954_at	0.293	8.103	3.132	6.760e-03	0.315	-2.282	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	16	2503953	NM_001694	527	16p13.3	Hs.389107	23	protein binding vacuole ion transport ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting V-type ATPase, V0 domain interspecies interaction between organisms proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
217978_s_at	-0.282	7.870	-3.132	6.764e-03	0.315	-2.282	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	1	-152787674	NM_017582	55585	1q21.3	Hs.607928	7	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
217935_s_at	-0.386	8.709	-3.129	6.800e-03	0.315	-2.287	UQCC	ubiquinol-cytochrome c reductase complex chaperone	20	-33353794	NM_018244	55245	20q11.22	Hs.714359	16	cytoplasmic vesicle
202453_s_at	-0.298	5.694	-3.129	6.800e-03	0.315	-2.287	GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	11	18300391	NM_005316	2965	11p15.1-p14	Hs.577202	77	regulation of cyclin-dependent protein kinase activity nucleotide-excision repair, DNA damage removal protein binding nucleus nucleoplasm holo TFIIH complex DNA repair transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter response to DNA damage stimulus RNA polymerase II carboxy-terminal domain kinase activity general RNA polymerase II transcription factor activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Basal transcription factors Nucleotide excision repair
211992_at	0.301	9.142	3.129	6.806e-03	0.315	-2.288	WNK1	WNK lysine deficient protein kinase 1	12	732485	AI445745	65125	12p13.3	Hs.709894	51	nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process
203375_s_at	-0.378	7.546	-3.128	6.817e-03	0.315	-2.289	TPP2	tripeptidyl peptidase II	13	102047286	NM_003291	7174	13q32-q33	Hs.432424	23	aminopeptidase activity serine-type endopeptidase activity cytoplasm proteolysis peptidase activity tripeptidyl-peptidase activity
207067_s_at	0.242	4.696	3.127	6.835e-03	0.315	-2.292	HDC	histidine decarboxylase	15	-48321437	NM_002112	3067	15q21-q22	Hs.1481	37	histidine decarboxylase activity cellular amino acid and derivative metabolic process histidine metabolic process lyase activity carboxylic acid metabolic process pyridoxal phosphate binding catecholamine biosynthetic process	Histidine metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
1552770_s_at	0.295	4.807	3.127	6.836e-03	0.315	-2.292	ZNF563	zinc finger protein 563	19	-12289305	NM_145276	147837	19p13.2	Hs.663510	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202829_s_at	-0.377	7.722	-3.126	6.840e-03	0.315	-2.292	VAMP7	vesicle-associated membrane protein 7	X, Y	154764140, 57623340	NM_005638	6845	Xq28 Yq12	Hs.24167	38	protein binding protein binding lysosomal membrane endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ER to Golgi vesicle-mediated transport vesicle fusion phagocytosis, engulfment endosome to lysosome transport protein transport membrane integral to membrane calcium ion-dependent exocytosis SNARE complex cytoplasmic vesicle late endosome membrane eosinophil degranulation neutrophil degranulation apical part of cell phagocytic vesicle	SNARE interactions in vesicular transport
205657_at	0.252	6.751	3.126	6.846e-03	0.315	-2.293	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	2	-42847732	NM_012205	23498	2p21	Hs.368805	12	3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity soluble fraction cytoplasm cytosol cytosol ferrous iron binding electron carrier activity response to zinc ion oxidoreductase activity pyridine nucleotide biosynthetic process NAD metabolic process quinolinate biosynthetic process response to cadmium ion metal ion binding oxidation reduction neuron maintenance	Tryptophan metabolism Metabolic pathways
1559871_s_at	0.501	4.114	3.126	6.848e-03	0.315	-2.293	LOC100129129	hypothetical protein LOC100129129	8		BC038546	100129129	8p23.1	Hs.662094
38037_at	-0.490	6.686	-3.126	6.849e-03	0.315	-2.293	HBEGF	heparin-binding EGF-like growth factor	5	-139692611	M60278	1839	5q23	Hs.592942 Hs.799	98	receptor activity epidermal growth factor receptor binding extracellular region extracellular space plasma membrane integral to plasma membrane signal transduction epidermal growth factor receptor signaling pathway muscle organ development regulation of heart contraction growth factor activity heparin binding cell surface wound healing, spreading of epidermal cells positive regulation of smooth muscle cell proliferation positive regulation of keratinocyte migration	ErbB signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection
200973_s_at	-0.622	9.408	-3.126	6.850e-03	0.315	-2.294	TSPAN3	tetraspanin 3	15	-75125385	NM_005724	10099	15q24.3	Hs.5062 Hs.716484	8	membrane integral to membrane
218235_s_at	-0.508	10.276	-3.125	6.852e-03	0.315	-2.294	UTP11L	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)	1	38250970	NM_016037	51118	1p34.3	Hs.472038 Hs.637686	11	protein binding extracellular space nucleus nucleolus cytoplasm rRNA processing induction of apoptosis nervous system development small-subunit processome nerve growth factor receptor signaling pathway
202429_s_at	-0.604	8.493	-3.125	6.857e-03	0.315	-2.294	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	AL353950	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
221713_s_at	-0.493	6.499	-3.125	6.861e-03	0.315	-2.295	MAP6D1	MAP6 domain containing 1	3	-185016357	BC006434	79929	3q27.1	Hs.478465	4	calmodulin binding cytoplasm Golgi apparatus Golgi-associated vesicle cis-Golgi network cytoskeleton negative regulation of microtubule depolymerization microtubule binding N-terminal peptidyl-L-cysteine N-palmitoylation
222588_s_at	-0.341	6.003	-3.124	6.875e-03	0.316	-2.297	C11orf57	chromosome 11 open reading frame 57	11	111450177	AA024582	55216	11q23.1	Hs.195060	6
227219_x_at	0.302	7.879	3.123	6.890e-03	0.316	-2.299	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	BE857601	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
220721_at	0.298	4.428	3.123	6.891e-03	0.316	-2.299	ZNF614	zinc finger protein 614	19	-57208389	NM_025040	80110	19q13.41	Hs.292336	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214987_at	-0.278	5.482	-3.122	6.894e-03	0.316	-2.299	GAB1	GRB2-associated binding protein 1	4	144477432	AL049449	2549	4q31.21	Hs.618456 Hs.80720	69	SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway	ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma
1553960_at	0.576	7.328	3.122	6.902e-03	0.316	-2.300	SNX21	sorting nexin family member 21	20	43895876	CA447177	90203	20q13.12	Hs.472854	8	protein binding cell communication protein transport phosphoinositide binding
218168_s_at	-0.428	11.345	-3.121	6.914e-03	0.316	-2.302	CABC1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	1	225194560	NM_020247	56997	1q42.13	Hs.118241	10	nucleotide binding ATP binding mitochondrion cell death kinase activity transferase activity
207430_s_at	-0.338	3.544	-3.121	6.920e-03	0.316	-2.303	MSMB	microseminoprotein, beta-	10	51219558	NM_002443	4477	10q11.2	Hs.255462	46	molecular_function extracellular region extracellular space nucleus biological_process
241899_at	0.310	5.396	3.120	6.922e-03	0.316	-2.303	LOC553103	hypothetical LOC553103			AA524418	553103		Hs.633421	1
212214_at	-0.410	8.123	-3.120	6.932e-03	0.316	-2.304	OPA1	optic atrophy 1 (autosomal dominant)	3	194793626	BF439570	4976	3q28-q29	Hs.594504	86	nucleotide binding mitochondrial fission magnesium ion binding GTPase activity GTP binding mitochondrion mitochondrial outer membrane mitochondrial intermembrane space apoptosis mitochondrion organization inner mitochondrial membrane organization visual perception mitochondrial fusion membrane integral to membrane axon transport of mitochondrion mitochondrial crista dendrite positive regulation of anti-apoptosis response to stimulus
214901_at	0.387	5.371	3.118	6.956e-03	0.317	-2.307	ZNF8	zinc finger protein 8	19	63482129	AI671579	7554	19q13.43	Hs.590941 Hs.713519	8	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding BMP signaling pathway metal ion binding
209522_s_at	0.474	9.483	3.118	6.957e-03	0.317	-2.307	CRAT	carnitine acetyltransferase	9	-130896895, -130896893	BC000723	1384	9q34.1	Hs.12068	10	carnitine O-acetyltransferase activity mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum lipid metabolic process fatty acid metabolic process transport acyltransferase activity energy derivation by oxidation of organic compounds membrane transferase activity
210658_s_at	-0.341	5.965	-3.117	6.966e-03	0.317	-2.309	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	16	-23383143	BC000284	23062	16p12	Hs.460336	37	protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding	Lysosome
227100_at	-0.478	5.464	-3.116	6.979e-03	0.317	-2.310	B3GALTL	beta 1,3-galactosyltransferase-like	13	30672111	AI569766	145173	13q12.3	Hs.13205	11	endoplasmic reticulum carbohydrate metabolic process fucose metabolic process membrane integral to membrane transferase activity, transferring glycosyl groups
37950_at	-0.414	7.856	-3.115	6.994e-03	0.317	-2.312	PREP	prolyl endopeptidase	6	-105832198	X74496	5550	6q22	Hs.436564	26	serine-type endopeptidase activity cytoplasm proteolysis peptidase activity
228482_at	0.396	3.801	3.115	7.000e-03	0.317	-2.313	CDRT4	CMT1A duplicated region transcript 4	17	-15280062	AV702789	284040	17p12	Hs.164595	4
223589_at	0.322	5.059	3.114	7.014e-03	0.317	-2.315	ZNF416	zinc finger protein 416	19	-62774745	BC000130	55659	19q13.4	Hs.247711	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202816_s_at	-0.286	4.986	-3.114	7.015e-03	0.317	-2.315	SS18	synovial sarcoma translocation, chromosome 18	18	-21850214	AW292882	6760	18q11.2	Hs.404263	32	nucleus
223041_at	-0.414	7.409	-3.113	7.028e-03	0.317	-2.316	CD99L2	CD99 molecule-like 2	X	-149685466	AL136580	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
222808_at	-0.365	4.384	-3.111	7.051e-03	0.317	-2.319	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	BC005336	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
225131_at	-0.524	7.856	-3.111	7.053e-03	0.317	-2.320	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	H60265	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
242272_at	0.309	5.954	3.110	7.074e-03	0.317	-2.322	ZNF785	zinc finger protein 785	16	-30499494	AI375066	146540	16p11.2	Hs.513509	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
227761_at	0.396	5.516	3.109	7.080e-03	0.317	-2.323	MYO5A	myosin VA (heavy chain 12, myoxin)	15	-50386774	AW235548	4644	15q21	Hs.21213 Hs.596221	47	microfilament motor activity nucleotide binding ruffle calmodulin binding ATP binding cytoplasm transport myosin complex actin filament-based movement growth cone neuron projection actin filament binding
204308_s_at	0.258	6.888	3.109	7.085e-03	0.317	-2.324	TECPR2	tectonin beta-propeller repeat containing 2	14	101899130	NM_014844	9895	14q32.31	Hs.195667	3
224276_at	0.352	3.695	3.109	7.090e-03	0.317	-2.324	ZNF33A	zinc finger protein 33A	10	38339583	AF063599	7581	10p11.2	Hs.435774	8	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222126_at	0.244	5.403	3.109	7.093e-03	0.317	-2.325	AGFG2	ArfGAP with FG repeats 2	7	99974769	AI247494	3268	7q22.1	Hs.521083	9	molecular_function cellular_component ARF GTPase activator activity biological_process zinc ion binding regulation of ARF GTPase activity metal ion binding
209495_at	0.294	6.205	3.109	7.093e-03	0.317	-2.325	CEP250	centrosomal protein 250kDa	20	33506563	AF022655	11190	20q11.22-q12	Hs.443976	14	mitotic cell cycle cytoplasm centriole cilium microtubule basal body protein C-terminus binding protein localization protein kinase binding regulation of centriole-centriole cohesion protein complex perinuclear region of cytoplasm
207705_s_at	0.607	6.329	3.108	7.099e-03	0.317	-2.326	NINL	ninein-like	20	-25381337	NM_025176	22981	20p11.22-p11.1	Hs.696157	13	calcium ion binding cytoplasm centrosome microtubule
201670_s_at	0.487	6.420	3.107	7.114e-03	0.317	-2.327	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	M68956	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
212861_at	-0.329	6.426	-3.107	7.115e-03	0.317	-2.328	MFSD5	major facilitator superfamily domain containing 5	12	51932146	BF690150	84975	12q13.13	Hs.654660	7	transport membrane integral to membrane
223490_s_at	-0.351	5.070	-3.107	7.119e-03	0.317	-2.328	EXOSC3	exosome component 3	9	-37770307, -37770307	AF281132	51010	9p11	Hs.602571 Hs.713483	12	3'-5'-exoribonuclease activity nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing hydrolase activity	RNA degradation
213178_s_at	0.493	6.065	3.106	7.133e-03	0.318	-2.330	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	16	1696221	AB028989	23162	16p13.3	Hs.207763	23	Golgi membrane MAP-kinase scaffold activity cytoplasm vesicle-mediated transport kinesin binding protein kinase binding regulation of JNK cascade	MAPK signaling pathway
204118_at	0.398	4.535	3.106	7.136e-03	0.318	-2.330	CD48	CD48 molecule	1	-158915159	NM_001778	962	1q21.3-q22	Hs.243564	35	protein binding plasma membrane integral to plasma membrane defense response anchored to membrane membrane raft	Natural killer cell mediated cytotoxicity
213380_x_at	0.305	5.443	3.105	7.151e-03	0.318	-2.332	MSTP9	macrophage stimulating, pseudogene 9	1	-16953988	AA911235	11223	1p36.13	Hs.349110 Hs.655432	2	serine-type endopeptidase activity extracellular region proteolysis peptidase activity
230822_at	0.296	4.496	3.105	7.152e-03	0.318	-2.332	TMEM61	transmembrane protein 61	1	55219052	AI766925	199964	1p32.3	Hs.663950	3	membrane integral to membrane
230066_at	0.277	3.507	3.103	7.170e-03	0.318	-2.334	SNX25	sorting nexin 25	4	186368277	AW134876	83891	4q35.1	Hs.369091	4	signal transducer activity protein binding cell communication protein transport phosphoinositide binding
207213_s_at	-0.658	7.347	-3.103	7.178e-03	0.318	-2.336	USP2	ubiquitin specific peptidase 2	11	-118731134, -118731134	NM_004205	9099	11q23.3	Hs.524085	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm plasma membrane ubiquitin-dependent protein catabolic process peptidase activity
226287_at	0.646	4.718	3.102	7.187e-03	0.318	-2.337	CCDC34	coiled-coil domain containing 34	11	-27326994, -27316636	AI458313	91057	11p14.1	Hs.143733	4
235049_at	0.412	5.891	3.101	7.200e-03	0.318	-2.338	ADCY1	adenylate cyclase 1 (brain)	7	45580649	AA021120	107	7p13-p12	Hs.192215	24	nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis
214279_s_at	-1.204	9.481	-3.100	7.219e-03	0.319	-2.340	NDRG2	NDRG family member 2	14	-20554761, -20554761	W74452	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
230292_at	0.466	6.050	3.099	7.232e-03	0.319	-2.342	LOC100131993	similar to hCG2020760	13		AA868809	100131993	13q14.2	Hs.709358
227945_at	-0.785	7.217	-3.096	7.278e-03	0.320	-2.348	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	BE882538	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
203666_at	0.575	7.941	3.096	7.281e-03	0.320	-2.348	CXCL12	chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)	10	-44192515, -44191370, -44185610	NM_000609	6387	10q11.1	Hs.522891	435	signal transducer activity extracellular region extracellular space cellular calcium ion homeostasis chemotaxis immune response cell adhesion signal transduction G-protein coupled receptor protein signaling pathway chemokine activity blood circulation regulation of actin polymerization or depolymerization growth factor activity response to virus	Cytokine-cytokine receptor interaction Chemokine signaling pathway Axon guidance Leukocyte transendothelial migration
1555350_at	-0.293	3.626	-3.096	7.282e-03	0.320	-2.348	PPHLN1	periphilin 1	12	41006213, 41006213, 41006213, 41006213	AY039238	51535	12q12	Hs.444157	13	nucleus cytoplasm keratinization
227951_s_at	0.487	5.800	3.096	7.285e-03	0.320	-2.349	FAM98C	family with sequence similarity 98, member C	19	43585614	AW338561	147965	19q13.2	Hs.355162	2
202588_at	-0.344	8.800	-3.095	7.288e-03	0.320	-2.349	AK1	adenylate kinase 1	9	-129668579	NM_000476	203	9q34.1	Hs.175473	24	nucleotide binding adenylate kinase activity protein binding ATP binding nucleus cytoplasm mitochondrion cytosol plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle arrest transferase activity nucleoside kinase activity ATP metabolic process	Purine metabolism Metabolic pathways
218919_at	-0.333	7.043	-3.095	7.301e-03	0.320	-2.351	ZFAND1	zinc finger, AN1-type domain 1	8	-82776512	NM_024699	79752	8q21.13	Hs.655453	4	zinc ion binding metal ion binding
1552739_s_at	-0.262	5.334	-3.093	7.321e-03	0.320	-2.353	ST7L	suppression of tumorigenicity 7 like	1	-112885935, -112867663	NM_138729	54879	1p13.2	Hs.201921	6	membrane integral to membrane
205588_s_at	0.468	4.110	3.091	7.359e-03	0.321	-2.358	FGFR1OP	FGFR1 oncogene partner	6	167332805	NM_007045	11116	6q27	Hs.487175	14	centrosome positive regulation of cell proliferation microtubule anchoring
205388_at	-0.788	13.323	-3.090	7.361e-03	0.321	-2.358	TNNC2	troponin C type 2 (fast)	20	-43885261	NM_003279	7125	20q12-q13.11	Hs.182421	12	skeletal muscle contraction actin binding calcium ion binding troponin complex regulation of muscle contraction	Calcium signaling pathway
201095_at	0.388	5.010	3.090	7.373e-03	0.321	-2.359	DAP	death-associated protein	5	-10732341	NM_004394	1611	5p15.2	Hs.75189	9	apoptosis induction of apoptosis by extracellular signals
202315_s_at	0.461	4.790	3.090	7.375e-03	0.321	-2.360	BCR	breakpoint cluster region	22	21852551	NM_004327	613	22q11 22q11.23	Hs.517461 Hs.715409	201	nucleotide binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity ATP binding intracellular protein amino acid phosphorylation intracellular signaling cascade kinase activity transferase activity regulation of Rho protein signal transduction	Pathways in cancer Chronic myeloid leukemia
227409_at	-0.499	6.106	-3.085	7.447e-03	0.323	-2.368	PPP1R3E	protein phosphatase 1, regulatory (inhibitor) subunit 3E	14	-22834952	AA167748	90673	14q11.2	Hs.601513 Hs.672733	3	carbohydrate metabolic process glycogen metabolic process
223000_s_at	0.411	6.332	3.085	7.450e-03	0.323	-2.369	F11R	F11 receptor	1	-159231624	AF172398	50848	1q21.2-q21.3	Hs.517293	63	protein binding plasma membrane cell-cell junction tight junction inflammatory response cell adhesion integral to membrane epithelial cell differentiation interspecies interaction between organisms	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
201779_s_at	-0.447	9.059	-3.084	7.463e-03	0.323	-2.370	RNF13	ring finger protein 13	3	151013164	AF070558	11342	3q25.1	Hs.12333 Hs.712766	10	protein binding nucleus cytoplasm zinc ion binding metal ion binding
222705_s_at	0.383	3.865	3.083	7.468e-03	0.323	-2.371	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	13	40261546	BC002702	10166	13q14	Hs.646645 Hs.655240	17	urea cycle L-ornithine transmembrane transporter activity mitochondrial ornithine transport transporter activity binding mitochondrion mitochondrial inner membrane cellular amino acid metabolic process transport membrane integral to membrane
214838_at	0.340	5.580	3.083	7.473e-03	0.323	-2.372	SFT2D2	SFT2 domain containing 2	1	166461878	AL035297	375035	1q24.2	Hs.645435	7	protein transport membrane integral to membrane
205040_at	0.464	4.148	3.083	7.474e-03	0.323	-2.372	ORM1	orosomucoid 1	9	116125123	NM_000607	5004	9q31-q32	Hs.522356	55	regulation of immune system process protein binding extracellular region extracellular space acute-phase response inflammatory response
205216_s_at	-0.264	4.469	-3.083	7.475e-03	0.323	-2.372	APOH	apolipoprotein H (beta-2-glycoprotein I)	17	-61638608	NM_000042	350	17q23-qter	Hs.445358	129	negative regulation of endothelial cell proliferation glycoprotein binding phospholipid binding extracellular region extracellular space triglyceride metabolic process blood coagulation, intrinsic pathway heparin binding cell surface negative regulation of endothelial cell migration negative regulation of angiogenesis positive regulation of blood coagulation negative regulation of blood coagulation organ regeneration plasminogen activation negative regulation of myeloid cell apoptosis triglyceride transport very-low-density lipoprotein particle high-density lipoprotein particle negative regulation of smooth muscle cell apoptosis chylomicron eukaryotic cell surface binding positive regulation of lipoprotein lipase activity negative regulation of fibrinolysis lipoprotein lipase activator activity
209943_at	-0.833	5.450	-3.083	7.482e-03	0.323	-2.373	FBXL4	F-box and leucine-rich repeat protein 4	6	-99428321	AF176699	26235	6q16.1-q16.3	Hs.536850	6	ubiquitin ligase complex nucleus cytoplasm ubiquitin-dependent protein catabolic process
233461_x_at	0.599	5.286	3.082	7.488e-03	0.323	-2.373	ZNF226	zinc finger protein 226	19	49361088, 49361088, 49361096, 49361156	AK023091	7769	19q13.2	Hs.145956	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229262_at	-0.249	5.139	-3.082	7.489e-03	0.323	-2.373	LRRC68	leucine rich repeat containing 68	19		AW027563	284352	19q13.32	Hs.285363	3
226587_at	0.854	7.172	3.081	7.500e-03	0.323	-2.375	SNRPN	small nuclear ribonucleoprotein polypeptide N	15	22619886, 22652790, 22751227	BE783065	6638	15q11.2	Hs.555970 Hs.564847 Hs.578619 Hs.585703 Hs.592473 Hs.621316 Hs.632166	47	RNA binding nucleus spliceosomal complex RNA splicing small nuclear ribonucleoprotein complex identical protein binding
201686_x_at	-0.281	5.513	-3.080	7.521e-03	0.324	-2.377	API5	apoptosis inhibitor 5	11	43290080	AF229254	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
226433_at	-0.921	7.026	-3.080	7.527e-03	0.324	-2.378	RNF157	ring finger protein 157	17	-71650128	BF056204	114804	17q25.1	Hs.500643	3	protein binding zinc ion binding metal ion binding
204572_s_at	-0.357	5.736	-3.078	7.550e-03	0.324	-2.381	PIN4	protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)	X	71318250	NM_006223	5303	Xq13	Hs.655623	13	peptidyl-prolyl cis-trans isomerase activity nucleolus cytoplasm mitochondrion mitochondrial matrix spindle protein folding isomerase activity
205589_at	0.373	12.188	3.078	7.552e-03	0.324	-2.381	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	3	-46874360	NM_000258	4634	3p21.3-p21.2	Hs.517939	27	regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex regulation of striated muscle contraction structural constituent of muscle myosin complex A band I band myosin II heavy chain binding positive regulation of ATPase activity ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
211947_s_at	-0.327	4.975	-3.078	7.553e-03	0.324	-2.381	BAT2D1	BAT2 domain containing 1	1	169721289	AI359472	23215	1q23.3	Hs.494614	5
209331_s_at	-0.373	5.527	-3.077	7.562e-03	0.324	-2.382	MAX	MYC associated factor X	14	-64620214, -64614273, -64611597, -64542644	AA723514	4149	14q23	Hs.285354 Hs.712926	56	transcription factor activity transcription coactivator activity protein binding nucleus cytoplasm transcription from RNA polymerase II promoter regulation of transcription	MAPK signaling pathway Pathways in cancer Small cell lung cancer
213982_s_at	0.647	4.676	3.077	7.571e-03	0.324	-2.383	RABGAP1L	RAB GTPase activating protein 1-like	1	172395256, 173111306	BG107203	9910	1q24	Hs.585378	9	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
226019_at	-0.509	7.391	-3.076	7.580e-03	0.324	-2.384	OMA1	OMA1 homolog, zinc metallopeptidase (S. cerevisiae)	1	-58718978	AI927931	115209	1p32.2-p32.1	Hs.425769	4	metalloendopeptidase activity mitochondrion proteolysis peptidase activity zinc ion binding membrane integral to membrane metal ion binding
219263_at	-0.613	6.831	-3.076	7.580e-03	0.324	-2.384	RNF128	ring finger protein 128	X	105823723, 105856549	NM_024539	79589	Xq22.3	Hs.496542	13	protein binding cytoplasm zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding perinuclear region of cytoplasm
203404_at	0.394	6.255	3.076	7.582e-03	0.324	-2.384	ARMCX2	armadillo repeat containing, X-linked 2	X	-100796925	NM_014782	9823	Xq21.33-q22.2	Hs.48924	7	binding membrane integral to membrane
224751_at	-0.465	8.277	-3.076	7.583e-03	0.324	-2.385	PL-5283	PL-5283 protein	7	134997760	BE738276	647087	7q33	Hs.200022	3
201241_at	-0.429	9.959	-3.076	7.588e-03	0.324	-2.385	DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	2	15649220	NM_004939	1653	2p24	Hs.440599	24	nucleotide binding spliceosome assembly RNA binding RNA helicase activity protein binding ATP binding cellular_component regulation of translational initiation multicellular organismal development ATP-dependent helicase activity hydrolase activity ribonucleoprotein complex
1560390_s_at	0.290	3.039	3.075	7.596e-03	0.324	-2.386	LOC284440	hypothetical LOC284440	19	-19728182	BI599587	284440	19p13.11	Hs.665307	4
205931_s_at	0.444	4.227	3.074	7.622e-03	0.324	-2.389	CREB5	cAMP responsive element binding protein 5	7	28305464, 28418668, 28441758, 28692245	NM_004904	9586	7p15.1	Hs.437075	10	transcription factor activity intracellular nucleus transcription from RNA polymerase II promoter zinc ion binding sequence-specific DNA binding positive regulation of transcription, DNA-dependent metal ion binding protein dimerization activity	Huntington's disease Prostate cancer
235754_at	0.322	4.308	3.072	7.649e-03	0.325	-2.392	HFE	hemochromatosis	6	26195487	AA088873	3077	6p21.3	Hs.233325	592	antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome
203565_s_at	-0.371	7.850	-3.071	7.656e-03	0.325	-2.393	MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	14	60271222	NM_002431	4331	14q23	Hs.509523	66	regulation of cyclin-dependent protein kinase activity nucleotide-excision repair, DNA damage removal nucleus nucleoplasm cytoplasm DNA repair transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter protein complex assembly apoptosis cell cycle adult heart development zinc ion binding cell proliferation ventricular system development multicellular organismal metabolic process positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter metal ion binding protein N-terminus binding regulation of catalytic activity response to calcium ion	Nucleotide excision repair
225173_at	-0.415	6.987	-3.071	7.660e-03	0.325	-2.394	ARHGAP18	Rho GTPase activating protein 18	6	-129939932	BE501862	93663	6q22.33	Hs.486458 Hs.708586	7	GTPase activator activity protein binding intracellular signal transduction
201017_at	-0.762	8.116	-3.070	7.676e-03	0.325	-2.396	EIF1AX	eukaryotic translation initiation factor 1A, X-linked	X	-20052556	BG149698	1964	Xp22.12	Hs.522590	17	RNA binding translation initiation factor activity cytoplasm cytosol translational initiation
217783_s_at	-0.295	8.135	-3.070	7.680e-03	0.325	-2.396	YPEL5	yippee-like 5 (Drosophila)	2	30223253	NM_016061	51646	2p23.1	Hs.515890	6
1556121_at	-0.636	6.152	-3.069	7.699e-03	0.325	-2.398	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AK021751	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
224856_at	-1.002	8.312	-3.068	7.704e-03	0.325	-2.399	FKBP5	FK506 binding protein 5	6	-35656311, -35649339, -35649339, -35649339	W86302	2289	6p21.3-p21.2	Hs.407190	50	peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding
214693_x_at	0.520	5.981	3.068	7.706e-03	0.325	-2.399	NBPF10	neuroblastoma breakpoint family, member 10	1	144004727	BE732345	100132406	1q21.1	Hs.515947	6	cytoplasm
230595_at	0.479	5.731	3.066	7.738e-03	0.326	-2.403	LOC572558	hypothetical locus LOC572558	9	-70159930	BF677651	572558	9q13	Hs.552819 Hs.9015	2
227199_at	0.465	6.555	3.066	7.743e-03	0.326	-2.403	DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	21	46703289, 46703289, 46703289, 46703289, 46703289	AW027812	23181	21q22.3	Hs.189585	11	catalytic activity nucleus multicellular organismal development transcription factor binding metabolic process
1554483_at	0.320	6.345	3.066	7.748e-03	0.326	-2.404	TMEM37	transmembrane protein 37	2	119905915	AF361356	140738	2q14.2	Hs.26216	3	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane
214992_s_at	-0.485	5.483	-3.065	7.761e-03	0.326	-2.405	DNASE2	deoxyribonuclease II, lysosomal	19	-12847024	AD000092	1777	19p13.2	Hs.118243	27	DNA binding endodeoxyribonuclease activity deoxyribonuclease II activity protein binding lysosome DNA catabolic process apoptosis multicellular organismal development hydrolase activity erythrocyte differentiation	Lysosome
204685_s_at	-1.250	7.048	-3.064	7.777e-03	0.326	-2.407	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	3	-10340706	R52647	491	3p25.3	Hs.268942	30	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding cytoplasm plasma membrane ATP biosynthetic process cation transport calcium ion transport sensory perception of sound metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances neuron differentiation	Calcium signaling pathway
221974_at	0.851	8.224	3.064	7.778e-03	0.326	-2.407	IPW	imprinted in Prader-Willi syndrome (non-protein coding)	15	22912784	AW770748	3653	15q11-q12	Hs.555970	3
235863_at	-0.366	6.936	-3.061	7.814e-03	0.328	-2.411	JSRP1	junctional sarcoplasmic reticulum protein 1	19	-2203251	AI805145	126306	19p13.3	Hs.712901	4	membrane sarcoplasmic reticulum membrane
243980_at	0.247	4.330	3.061	7.817e-03	0.328	-2.412	ZNF594	zinc finger protein 594	17	-5023554	AW978739	84622	17p13	Hs.658402	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1569906_s_at	-0.325	6.371	-3.061	7.828e-03	0.328	-2.413	PHF20	PHD finger protein 20	20	33823336	BC015538	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
206996_x_at	-0.281	9.524	-3.060	7.839e-03	0.328	-2.414	CACNB1	calcium channel, voltage-dependent, beta 1 subunit	17	-34586914, -34583234	NM_000723	782	17q21-q22	Hs.635	18	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
223136_at	0.651	7.015	3.056	7.893e-03	0.329	-2.420	AIG1	androgen-induced 1	6	143423715	AF151861	51390	6q24.2	Hs.567501	8	membrane integral to membrane
208091_s_at	-0.371	8.084	-3.056	7.893e-03	0.329	-2.420	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	7	-55505799	NM_030796	81552	7p11.2	Hs.488307	17
223822_at	0.456	4.359	3.056	7.904e-03	0.329	-2.422	SUSD4	sushi domain containing 4	1	-221474874, -221460783	BC004888	55061	1q41	Hs.497841	4	membrane integral to membrane
1558723_at	0.242	3.250	3.056	7.907e-03	0.329	-2.422	LOC284014	hypothetical protein LOC284014	17		AK095567	284014	17p13.3	Hs.131035	1
205730_s_at	0.580	6.986	3.055	7.910e-03	0.329	-2.422	ABLIM3	actin binding LIM protein family, member 3	5	148501246	NM_014945	22885	5q32	Hs.49688	15	actin binding cytoplasm cytoskeleton organization zinc ion binding positive regulation of transcription from RNA polymerase II promoter metal ion binding	Axon guidance
221073_s_at	0.275	6.206	3.055	7.915e-03	0.329	-2.423	NOD1	nucleotide-binding oligomerization domain containing 1	7	-30430667	NM_006092	10392	7p15-p14	Hs.405153	72	nucleotide binding ATP binding intracellular cytoplasm induction of apoptosis activation of caspase activity inflammatory response intracellular signaling cascade caspase activator activity detection of bacterium positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade interleukin-8 biosynthetic process identical protein binding peptidoglycan binding regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JNK cascade CARD domain binding defense response to Gram-positive bacterium protein oligomerization positive regulation of ERK1 and ERK2 cascade	Epithelial cell signaling in Helicobacter pylori infection
209090_s_at	-0.479	9.676	-3.055	7.923e-03	0.329	-2.424	SH3GLB1	SH3-domain GRB2-like endophilin B1	1	86942844	AL049597	51100	1p22	Hs.136309	28	protein insertion into mitochondrial membrane during induction of apoptosis fatty acid binding protein binding nucleus cytoplasm mitochondrion mitochondrial outer membrane microsome Golgi apparatus phosphatidic acid biosynthetic process apoptosis anti-apoptosis phospholipid biosynthetic process membrane lysophosphatidic acid acyltransferase activity protein homodimerization activity protein complex 'de novo' posttranslational protein folding	Endocytosis
240459_at	-0.276	3.787	-3.054	7.927e-03	0.329	-2.424	YTHDC1	YTH domain containing 1	4	-68858699	AW467048	91746	4q13.2	Hs.175955	18	nucleus mRNA processing RNA splicing
222725_s_at	-0.576	7.474	-3.051	7.986e-03	0.330	-2.431	PALMD	palmdelphin	1	99884018	AI082747	54873	1p22-p21	Hs.483993	7	cytoplasm regulation of cell shape membrane
204159_at	-0.651	7.084	-3.051	7.988e-03	0.330	-2.431	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	1	51206954, 51208229	NM_001262	1031	1p32	Hs.525324 Hs.716664	45	regulation of cyclin-dependent protein kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm induction of apoptosis cell cycle cell cycle arrest negative regulation of cell proliferation protein kinase binding negative regulation of cell growth negative regulation of phosphorylation oligodendrocyte differentiation	Cell cycle
229820_at	0.474	5.322	3.050	7.994e-03	0.330	-2.432	LOC440993	hypothetical LOC440993	3		BF509179	440993	3q29	Hs.709411
209189_at	-1.321	5.703	-3.050	7.995e-03	0.330	-2.432	FOS	FBJ murine osteosarcoma viral oncogene homolog	14	74815233	BC004490	2353	14q24.3	Hs.707896	207	double-stranded DNA binding transcription factor activity specific RNA polymerase II transcription factor activity nucleus transcription factor complex nucleolus DNA methylation inflammatory response transforming growth factor beta receptor signaling pathway nervous system development promoter binding cellular response to extracellular stimulus cellular response to reactive oxygen species response to drug positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity SMAD protein signal transduction R-SMAD binding	MAPK signaling pathway Toll-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Pathways in cancer Colorectal cancer
238732_at	-0.412	3.122	-3.049	8.009e-03	0.331	-2.433	COL24A1	collagen, type XXIV, alpha 1	1	-85967503	AI631241	255631	1p22.3	Hs.659516	3	extracellular matrix structural constituent collagen cell adhesion
35436_at	-0.270	7.607	-3.046	8.068e-03	0.332	-2.440	GOLGA2	golgi autoantigen, golgin subfamily a, 2	9	-130057928	L06147	2801	9q34.11	Hs.155827	45	protein binding Golgi apparatus membrane
208149_x_at	0.472	5.717	3.045	8.079e-03	0.332	-2.441	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	12	31118045	NM_030653	1663	12p11	Hs.443960	13	mitotic sister chromatid segregation S phase of mitotic cell cycle G2/M transition of mitotic cell cycle nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP binding nucleus nucleolus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle positive regulation of cell proliferation hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
227646_at	0.524	6.777	3.044	8.090e-03	0.332	-2.442	EBF1	early B-cell factor 1	5	-158055500	BG435302	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
238594_x_at	0.328	7.318	3.043	8.115e-03	0.333	-2.445	DUSP8	dual specificity phosphatase 8	11	-1531856	AI864441	1850	11p15.5	Hs.41688	6	inactivation of MAPK activity protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
238116_at	0.240	2.408	3.043	8.120e-03	0.333	-2.446	DYNLRB2	dynein, light chain, roadblock-type 2	16	79132354	AW959427	83657	16q23.3	Hs.98849	5	microtubule motor activity protein binding cytoplasm cytoplasmic dynein complex microtubule microtubule-based movement
243309_at	-0.547	5.284	-3.042	8.123e-03	0.333	-2.446	FLJ27352	hypothetical LOC145788	15		AA398658	145788	15q21.3	Hs.97300
225607_at	-0.341	8.256	-3.042	8.135e-03	0.333	-2.447	CCDC43	coiled-coil domain containing 43	17	-40110330	AI948491	124808	17q21.31	Hs.579115	2
209783_at	-0.223	5.660	-3.041	8.155e-03	0.333	-2.450	DBP	D site of albumin promoter (albumin D-box) binding protein	19	-53825628	D28468	1628	19q13.3	Hs.414480 Hs.528006	35	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter regulation of cell proliferation sequence-specific DNA binding protein dimerization activity rhythmic process
218210_at	0.378	6.582	3.040	8.160e-03	0.333	-2.450	FN3KRP	fructosamine 3 kinase related protein	17	78267870	NM_024619	79672	17q25.3	Hs.31431	12	kinase activity transferase activity
205914_s_at	-0.254	4.007	-3.039	8.173e-03	0.333	-2.452	GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	9	139153429	NM_007327	2902	9q34.3	Hs.558334	119	magnesium ion binding receptor activity N-methyl-D-aspartate selective glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity calcium channel activity calcium ion binding calmodulin binding plasma membrane integral to plasma membrane cation transport synaptic transmission synaptic vesicle visual learning postsynaptic density glycine binding glycine binding glutamate binding N-methyl-D-aspartate selective glutamate receptor complex synaptosome cell junction dendrite ionotropic glutamate receptor signaling pathway glutamate receptor binding regulation of membrane potential synapse postsynaptic membrane response to ethanol positive regulation of transcription from RNA polymerase II promoter calcium ion homeostasis regulation of excitatory postsynaptic membrane potential	Calcium signaling pathway Neuroactive ligand-receptor interaction Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Huntington's disease
219601_s_at	-0.249	2.943	-3.039	8.173e-03	0.333	-2.452	C10orf12	chromosome 10 open reading frame 12	10	98731030	NM_015652	26148	10q24.1	Hs.14555 Hs.427927	5
228476_at	0.291	4.216	3.039	8.176e-03	0.333	-2.452	KIAA1407	KIAA1407	3	-115165673	AW193515	57577	3q13.31	Hs.477159	1
228257_at	0.282	7.495	3.039	8.177e-03	0.333	-2.452	ANKRD52	ankyrin repeat domain 52	12	-54917857	AA458879	283373	12q13.3	Hs.524506	6	protein binding
225665_at	-0.375	11.862	-3.038	8.202e-03	0.334	-2.455	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AI129320	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
230422_at	-0.392	4.183	-3.038	8.206e-03	0.334	-2.455	FPR3	formyl peptide receptor 3	19	56990222	AW026543	2359	19q13.3-q13.4	Hs.445466	13	receptor activity G-protein coupled receptor activity N-formyl peptide receptor activity plasma membrane cell motion chemotaxis signal transduction G-protein coupled receptor protein signaling pathway integral to membrane	Neuroactive ligand-receptor interaction
200684_s_at	-0.437	6.645	-3.034	8.267e-03	0.335	-2.462	UBE2L3	ubiquitin-conjugating enzyme E2L 3	22	20251956	AI819709	7332	22q11.21	Hs.108104 Hs.603229 Hs.715088	38	ubiquitin ligase complex nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity enzyme binding regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
204319_s_at	-0.564	5.928	-3.034	8.271e-03	0.335	-2.462	RGS10	regulator of G-protein signaling 10	10	-121249328, -121249328	NM_002925	6001	10q25	Hs.501200	15	signal transducer activity protein binding negative regulation of signal transduction
205210_at	-0.243	5.527	-3.034	8.272e-03	0.335	-2.462	TGFBRAP1	transforming growth factor, beta receptor associated protein 1	2	-105249973	NM_004257	9392	2q12.1	Hs.446350	7	transforming growth factor beta receptor binding cytoplasm signal transduction transforming growth factor beta receptor signaling pathway membrane regulation of transcription SMAD binding
217873_at	-0.648	9.662	-3.033	8.284e-03	0.335	-2.464	CAB39	calcium binding protein 39	2	231285800, 231286506	NM_016289	51719	2q37.1	Hs.632536	14	protein binding cytoplasm	mTOR signaling pathway
230779_at	0.588	7.017	3.033	8.285e-03	0.335	-2.464	TNRC6B	trinucleotide repeat containing 6B	22	38770766, 38903874, 38903874	BF594371	23112	22q13.1	Hs.372082	15	nucleotide binding cytoplasmic mRNA processing body RNA binding cytoplasm regulation of translation gene silencing by RNA
206181_at	0.281	2.996	3.032	8.305e-03	0.335	-2.466	SLAMF1	signaling lymphocytic activation molecule family member 1	1	-158846514	NM_003037	6504	1q22-q23	Hs.523660	36	antigen binding transmembrane receptor activity plasma membrane positive regulation of cell proliferation cell surface integral to membrane interspecies interaction between organisms lymphocyte activation
229614_at	0.457	4.892	3.031	8.316e-03	0.335	-2.467	ZNF320	zinc finger protein 320	19	-58071236	AI277652	162967	19q13.41	Hs.446907	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201064_s_at	-0.385	9.863	-3.031	8.320e-03	0.335	-2.468	PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	1	-39799071	NM_003819	8761	1p32-p36	Hs.169900	17	nucleotide binding RNA binding protein binding cytoplasm RNA processing RNA catabolic process translation blood coagulation poly(A) RNA binding poly(U) RNA binding poly(C) RNA binding
201457_x_at	-0.355	6.984	-3.030	8.330e-03	0.335	-2.469	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	10	124903749	AF081496	9184	10q26	Hs.418533	28	kinetochore protein binding nucleus nucleolus cytosol mitosis mitotic cell cycle checkpoint cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle
219495_s_at	0.317	4.259	3.029	8.345e-03	0.335	-2.470	ZNF180	zinc finger protein 180	19	-49671698	NM_013256	7733	19q13.2	Hs.22305	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202566_s_at	-0.592	9.802	-3.029	8.349e-03	0.335	-2.471	SVIL	supervillin	10	-29786282, -29786282	AF051851	6840	10p11.2	Hs.499209	23	podosome calcium ion binding nucleus cytoplasm plasma membrane cytoskeleton organization skeletal muscle tissue development cell projection costamere actin filament binding
1570169_at	0.224	4.674	3.028	8.370e-03	0.335	-2.473	CSMD2	CUB and Sushi multiple domains 2	1	-33752195	BC031871	114784	1p35.1-p34.3	Hs.656915	9	protein binding plasma membrane integral to membrane
1569128_at	-0.222	2.412	-3.027	8.377e-03	0.335	-2.474	C3orf38	chromosome 3 open reading frame 38	3	88281582	BC016013	285237	3p11.1	Hs.476944 Hs.518099	2	apoptosis
207457_s_at	-0.279	4.492	-3.027	8.380e-03	0.335	-2.474	LY6G6D	lymphocyte antigen 6 complex, locus G6D	6	31791111, 3129252, 2930718	NM_021246	58530	6p21.3	Hs.591792	2	protein binding cytosol plasma membrane defense response response to unfolded protein response to nutrient anchored to membrane protein complex NF-kappaB binding
218115_at	0.300	5.553	3.027	8.384e-03	0.335	-2.474	ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	19	-14091320	NM_018154	55723	19p13.12	Hs.26516	15	chromatin nucleus chromatin assembly or disassembly nucleosome assembly multicellular organismal development spermatogenesis chromatin modification cell differentiation histone binding regulation of transcription
212653_s_at	0.326	7.281	3.027	8.387e-03	0.335	-2.475	EHBP1	EH domain binding protein 1	2	62754516, 62786504, 62787535	AB020710	23301	2p15	Hs.271667	13	cytoplasm membrane
222700_at	-0.556	7.622	-3.027	8.388e-03	0.335	-2.475	ATL2	atlastin GTPase 2	2	-38375534	AV700003	64225	2p22.2-p22.1	Hs.594950	8	nucleotide binding GTPase activity GTP binding membrane integral to membrane
1554127_s_at	-0.619	8.134	-3.025	8.421e-03	0.336	-2.478	MSRB3	methionine sulfoxide reductase B3	12	63958754	BC040053	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
210154_at	0.568	6.228	3.025	8.422e-03	0.336	-2.478	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	18	46659432	M55905	4200	18q21 6p25-p24	Hs.233119	24	malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide
240289_at	-0.881	7.611	-3.023	8.453e-03	0.337	-2.482	LOC100131683	hypothetical protein LOC100131683	4		W86910	100131683	4q35.1	Hs.442702
210007_s_at	-0.485	4.688	-3.023	8.454e-03	0.337	-2.482	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	2	157000210, 157001145	U36310	2820	2q24.1	Hs.512382	20	glycerol-3-phosphate dehydrogenase activity calcium ion binding mitochondrion mitochondrial inner membrane glycerol-3-phosphate metabolic process gluconeogenesis glycerol-3-phosphate dehydrogenase complex oxidoreductase activity oxidation reduction	Glycerophospholipid metabolism
1559630_at	0.253	3.876	3.022	8.471e-03	0.337	-2.484	DLGAP3	discs, large (Drosophila) homolog-associated protein 3	1	-35103623	R24798	58512	1p35.3-p34.1	Hs.436393	9	protein binding plasma membrane cell-cell signaling postsynaptic density cell junction synapse postsynaptic membrane
204663_at	0.297	7.408	3.022	8.478e-03	0.337	-2.484	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	11	-85829799, -85829797, -85829797	NM_006680	10873	11cen-q22.3	Hs.199743	8	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity mitochondrion mitochondrial matrix pyruvate metabolic process malate metabolic process oxygen and reactive oxygen species metabolic process aerobic respiration oxidoreductase activity metal ion binding cofactor binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways
212150_at	-0.511	8.492	-3.022	8.480e-03	0.337	-2.485	EFR3A	EFR3 homolog A (S. cerevisiae)	8	132985540	AA805651	23167	8q24.22	Hs.204564	4	binding plasma membrane
214815_at	0.389	4.959	3.021	8.496e-03	0.337	-2.486	TRIM33	tripartite motif-containing 33	1	-114736921	AU136587	51592	1p13.1	Hs.26837	12	DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding
1555567_s_at	-0.521	7.832	-3.020	8.512e-03	0.337	-2.488	LMOD3	leiomodin 3 (fetal)	3	-69238728	BC039202	56203	3p14.1	Hs.350621	9	tropomyosin binding cytoplasm cytoskeleton
48659_at	0.246	6.612	3.019	8.515e-03	0.337	-2.488	MIIP	migration and invasion inhibitory protein	1	12002098	W60802	60672	1p36.22	Hs.8595	4
202905_x_at	-0.442	5.938	-3.019	8.517e-03	0.337	-2.488	NBN	nibrin	8	-91014739	AI796269	4683	8q21	Hs.492208	222	DNA damage checkpoint telomere maintenance nuclear chromosome, telomeric region in utero embryonic development blastocyst growth damaged DNA binding intracellular nucleus nucleoplasm replication fork chromosome nucleolus Golgi apparatus double-strand break repair response to DNA damage stimulus cell cycle cell cycle arrest mitotic cell cycle G2/M transition DNA damage checkpoint meiosis transcription factor binding cell proliferation regulation of DNA replication initiation DNA damage response, signal transduction by p53 class mediator Mre11 complex G1/S transition checkpoint nuclear inclusion body isotype switching protein N-terminus binding regulation of fibroblast proliferation neuromuscular process controlling balance	Homologous recombination
228953_at	-0.483	6.967	-3.019	8.531e-03	0.337	-2.490	WHAMM	WAS protein homolog associated with actin, golgi membranes and microtubules	15	81275026	AI023634	123720	15q25.2	Hs.377360	5	actin binding cytoplasm ER-Golgi intermediate compartment Golgi apparatus membrane cytoplasmic vesicle membrane cytoplasmic vesicle
55662_at	-0.381	6.188	-3.018	8.540e-03	0.337	-2.491	C10orf76	chromosome 10 open reading frame 76	10	-103595345	H27225	79591	10q24.32	Hs.16004	4	membrane integral to membrane
201911_s_at	-0.651	5.912	-3.017	8.562e-03	0.337	-2.493	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	13	97593434, 97593434	NM_005766	10160	13q32.2	Hs.403917	9	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity binding intracellular cytoplasm cytoskeleton cytoskeletal protein binding extrinsic to membrane regulation of Rho protein signal transduction
212640_at	0.505	5.977	3.016	8.567e-03	0.337	-2.494	PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	3	-124696052	AV712602	201562	3q21.1	Hs.705480	5	protein binding endoplasmic reticulum membrane integral to membrane	Biosynthesis of unsaturated fatty acids
1569256_a_at	-0.290	5.689	-3.016	8.568e-03	0.337	-2.494	FAM43B	family with sequence similarity 43, member B	1	20751518	BC015675	163933	1p36.12	Hs.429179	3
228027_at	0.384	7.503	3.016	8.573e-03	0.337	-2.494	GPRASP2	G protein-coupled receptor associated sorting protein 2	X	101853995	BF732712	114928	Xq22.1	Hs.603154	11	protein binding cytoplasm
203957_at	-0.437	6.571	-3.016	8.578e-03	0.337	-2.495	E2F6	E2F transcription factor 6	2	-11501951	NM_001952	1876	2p25.1	Hs.603093	24	regulation of transcription of G1/S-phase of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription corepressor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle
238465_at	0.937	5.872	3.016	8.580e-03	0.337	-2.495	C5orf35	chromosome 5 open reading frame 35	5	56240859	AI265933	133383	5q11.2	Hs.85950	1
217325_at	-0.285	5.259	-3.016	8.583e-03	0.337	-2.495	KRT3	keratin 3	12	-51469735	X05421	3850	12q12-q13	Hs.680652	9	structural molecule activity structural molecule activity epithelial cell differentiation keratin filament intermediate filament cytoskeleton organization
227889_at	0.276	4.849	3.015	8.587e-03	0.337	-2.496	LPCAT2	lysophosphatidylcholine acyltransferase 2	16	54100413	AI765437	54947	16q12.2	Hs.460857	4	calcium ion binding endoplasmic reticulum Golgi apparatus Golgi stack platelet activating factor biosynthetic process metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane membrane organization transferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-alkylglycerophosphocholine O-acetyltransferase activity
225894_at	-0.425	11.477	-3.015	8.588e-03	0.337	-2.496	SYNPO2	synaptopodin 2	4	120029443, 120029443	AL589603	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
202750_s_at	-0.460	6.999	-3.014	8.609e-03	0.338	-2.498	TFIP11	tuftelin interacting protein 11	22	-25217894	AL080147	24144	22q12.1	Hs.20225	19	nucleic acid binding protein binding proteinaceous extracellular matrix intracellular nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing nuclear speck biomineral formation
203705_s_at	-0.624	7.321	-3.013	8.622e-03	0.338	-2.499	FZD7	frizzled homolog 7 (Drosophila)	2	202607554	AI333651	8324	2q33	Hs.173859	23	non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway multicellular organismal development integral to membrane Wnt receptor signaling pathway Wnt receptor activity	Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma
226588_at	-0.380	5.799	-3.012	8.644e-03	0.338	-2.502	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	2	-180517848	AB046824	57703	2q31.3	Hs.311363	6	RNA binding protein binding nucleus spliceosomal complex mRNA processing RNA splicing RNA metabolic process regulation of nuclear mRNA splicing, via spliceosome
219939_s_at	-0.278	12.053	-3.012	8.650e-03	0.338	-2.502	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	NM_007158	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
200849_s_at	-0.448	9.078	-3.011	8.657e-03	0.338	-2.503	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	AI589266	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
201488_x_at	0.275	9.629	3.011	8.662e-03	0.338	-2.504	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	1	32252077	BC000717	10657	1p32	Hs.709204	86	G2/M transition of mitotic cell cycle DNA binding RNA binding SH3/SH2 adaptor activity protein binding nucleus mRNA processing cell cycle cell cycle arrest cell surface receptor linked signal transduction cell proliferation membrane negative regulation of transcription transcription repressor activity SH3 domain binding regulation of RNA export from nucleus
233261_at	0.417	3.599	3.011	8.668e-03	0.338	-2.504	EBF1	early B-cell factor 1	5	-158055500	AU145682	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
221774_x_at	-0.253	5.992	-3.009	8.697e-03	0.338	-2.507	FAM48A	family with sequence similarity 48, member A	13	-36481450	AW003334	55578	13q13.3	Hs.435815	14	protein binding multicellular organismal development gastrulation
235547_at	0.768	3.938	3.009	8.698e-03	0.338	-2.507	N4BP2L2	NEDD4 binding protein 2-like 2	13	-31989029, -31904929	BG548427	10443	13q13.1	Hs.507680	4	molecular_function cellular_component biological_process
218265_at	-0.287	6.809	-3.009	8.706e-03	0.338	-2.508	SECISBP2	SECIS binding protein 2	9	91123231	NM_024077	79048	9q22.2	Hs.59804	20	RNA binding mRNA 3'-UTR binding nucleus translation
205478_at	0.513	11.526	3.008	8.716e-03	0.338	-2.509	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	12	-53259290	NM_006741	5502	12q13.2	Hs.505662	9	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process signal transduction	Long-term potentiation
223993_s_at	0.362	9.370	3.007	8.731e-03	0.338	-2.511	CNIH4	cornichon homolog 4 (Drosophila)	1	222611217	AL136930	29097	1q42.11	Hs.195403 Hs.445890	11	protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane
204059_s_at	0.571	9.227	3.007	8.733e-03	0.338	-2.511	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	6	-83976828	NM_002395	4199	6q12	Hs.21160	24	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway
219330_at	0.287	4.051	3.007	8.734e-03	0.338	-2.511	VANGL1	vang-like 1 (van gogh, Drosophila)	1	115986096	NM_024062	81839	1p11-p13.1	Hs.515130	12	protein binding multicellular organismal development membrane integral to membrane	Wnt signaling pathway
207145_at	-0.637	4.700	-3.007	8.737e-03	0.338	-2.511	MSTN	myostatin	2	-190628670	NM_005259	2660	2q32.2	Hs.41565	55	cytokine activity extracellular region extracellular space transforming growth factor beta receptor signaling pathway muscle organ development growth factor activity growth positive regulation of transcription
218790_s_at	0.312	5.262	3.007	8.740e-03	0.338	-2.512	TMLHE	trimethyllysine hydroxylase, epsilon	X	-154372966	NM_018196	55217	Xq28	Hs.133321	12	iron ion binding mitochondrion mitochondrial matrix mitochondrial matrix electron carrier activity oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding carnitine biosynthetic process trimethyllysine dioxygenase activity oxidation reduction	Lysine degradation
224583_at	0.475	4.477	3.007	8.742e-03	0.338	-2.512	COTL1	coactosin-like 1 (Dictyostelium)	16	-83156704	AL565621	23406	16q24.1	Hs.289092	18	actin binding cellular_component intracellular cytoplasm cytoskeleton biological_process enzyme binding defense response to fungus
235333_at	0.626	5.816	3.005	8.774e-03	0.339	-2.515	B4GALT6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	18	-27456206	BG503479	9331	18q11	Hs.591063	12	magnesium ion binding calcium ion binding Golgi apparatus carbohydrate metabolic process galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding	Sphingolipid metabolism Metabolic pathways
229552_at	-0.338	4.817	-3.003	8.804e-03	0.339	-2.518	LOC283454	hypothetical protein LOC283454	12		AI698128	283454	12q24.23	Hs.26605	1
235306_at	0.681	5.665	3.003	8.811e-03	0.339	-2.519	GIMAP8	GTPase, IMAP family member 8	7	149778894	AI611648	155038	7q36.1	Hs.647121	7	nucleotide binding GTP binding mitochondrion endoplasmic reticulum Golgi apparatus
220683_at	-0.302	5.002	-3.003	8.813e-03	0.339	-2.519	RDH8	retinol dehydrogenase 8 (all-trans)	19	9984924	NM_015725	50700	19p13.2-p13.3	Hs.675522	9	estradiol 17-beta-dehydrogenase activity retinol dehydrogenase activity binding cytoplasm integral to plasma membrane estrogen biosynthetic process visual perception membrane oxidoreductase activity response to stimulus oxidation reduction	Retinol metabolism Metabolic pathways
222885_at	0.344	8.351	3.003	8.813e-03	0.339	-2.519	EMCN	endomucin	4	-101535522	AF205940	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
201799_s_at	-0.408	6.906	-3.003	8.814e-03	0.339	-2.519	OSBP	oxysterol binding protein	11	-59098446	AI927993	5007	11q12-q13	Hs.597091	13	cytoplasm Golgi apparatus lipid transport oxysterol binding steroid metabolic process membrane
236022_at	0.275	5.085	3.002	8.828e-03	0.339	-2.521	MYO19	myosin XIX	17	-31943030, -31925712, -31925711	AI650341	80179	17q12	Hs.302051	3	nucleotide binding motor activity actin binding ATP binding cytoplasm myosin complex
204152_s_at	0.270	4.888	3.001	8.837e-03	0.339	-2.521	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	22	-36195048	AI738965	4242	22q12	Hs.517603	15	extracellular space Golgi apparatus pattern specification process membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Notch signaling pathway
202457_s_at	-0.606	9.104	-3.001	8.838e-03	0.339	-2.521	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	AA911231	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
210746_s_at	0.199	3.885	3.001	8.847e-03	0.339	-2.522	EPB42	erythrocyte membrane protein band 4.2	15	-41276717	M30646	2038	15q15-q21	Hs.368642	34	cell morphogenesis protein-glutamine gamma-glutamyltransferase activity structural constituent of cytoskeleton protein binding ATP binding cytoplasm plasma membrane regulation of cell shape peptide cross-linking hemoglobin metabolic process cortical cytoskeleton erythrocyte maturation spleen development ion homeostasis iron ion homeostasis
221601_s_at	1.099	4.906	3.001	8.848e-03	0.339	-2.522	FAIM3	Fas apoptotic inhibitory molecule 3	1	-205143252, -205143252	AI084226	9214	1q32.1	Hs.58831 Hs.719320	10	nucleus cytoplasm plasma membrane focal adhesion anti-apoptosis immune response cellular defense response integral to membrane
222798_at	0.598	7.204	2.998	8.895e-03	0.339	-2.527	PTER	phosphotriesterase related	10	16518972	BF112019	9317	10p12	Hs.444321 Hs.716660	6	zinc ion binding catabolic process hydrolase activity, acting on ester bonds metal ion binding
223191_at	-0.326	10.153	-2.998	8.897e-03	0.339	-2.527	COX16	COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)	14	-69861551	AF151037	51241	14q24.2	Hs.709581	5	mitochondrion membrane integral to membrane mitochondrial membrane
1558093_s_at	-0.592	5.991	-2.998	8.906e-03	0.339	-2.528	MATR3	matrin 3	5	138637690, 138657253	BI832461	9782	5q31.2	Hs.268939	24	nucleotide binding RNA binding structural molecule activity protein binding intracellular nucleus nuclear inner membrane zinc ion binding nuclear matrix metal ion binding
220939_s_at	-0.409	9.023	-2.997	8.910e-03	0.339	-2.529	DPP8	dipeptidyl-peptidase 8	15	-63525050, -63525050	NM_017743	54878	15q22	Hs.591106	16	aminopeptidase activity nucleus cytoplasm proteolysis immune response peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity membrane
212651_at	-1.401	8.536	-2.997	8.913e-03	0.339	-2.529	RHOBTB1	Rho-related BTB domain containing 1	10	-62299205, -62299205, -62299205	AB018283	9886	10q21.2	Hs.148670	10	nucleotide binding protein binding GTP binding intracellular small GTPase mediated signal transduction
1558969_a_at	0.223	5.256	2.997	8.922e-03	0.339	-2.530	RPL32P3	ribosomal protein L32 pseudogene 3	3	-130584366	BG741817	132241	3q21.3	Hs.477537 Hs.652423	2
205902_at	-0.477	6.119	-2.995	8.951e-03	0.340	-2.533	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1	-152946536, -152946536	AJ251016	3782	1q21.3	Hs.490765	40	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
229963_at	0.380	3.927	2.994	8.965e-03	0.340	-2.534	BEX5	brain expressed, X-linked 5	X	-101295335, -101295335	AV726956	340542	Xq22.1	Hs.47209	5	cytoplasm
226475_at	0.323	6.394	2.993	8.995e-03	0.340	-2.537	FAM118A	family with sequence similarity 118, member A	22	44083744, 44084448	AI650582	55007	22q13	Hs.265018	6	membrane integral to membrane
238647_at	-0.500	5.084	-2.993	8.995e-03	0.340	-2.537	C14orf28	chromosome 14 open reading frame 28	14	44436256	AA496213	122525	14q21.2	Hs.82098	3
202646_s_at	-0.327	11.463	-2.993	8.997e-03	0.340	-2.537	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	AA167775	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
1554868_s_at	-0.758	7.913	-2.992	9.005e-03	0.340	-2.538	PCNP	PEST proteolytic signal containing nuclear protein	3	102775731	BC013916	57092	3q12.3	Hs.545311 Hs.654949	6	protein binding nucleus cell cycle protein ubiquitination proteasomal ubiquitin-dependent protein catabolic process
227031_at	-0.426	7.445	-2.992	9.017e-03	0.340	-2.539	SNX13	sorting nexin 13	7	-17796910	AV681975	23161	7p21.1	Hs.487648	10	signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding
225274_at	-0.596	9.882	-2.991	9.021e-03	0.340	-2.540	PCYOX1	prenylcysteine oxidase 1	2	70338734	BF247054	51449	2p13.3	Hs.567502	13	prenylcysteine oxidase activity binding lysosome oxidoreductase activity prenylated protein catabolic process prenylcysteine catabolic process very-low-density lipoprotein particle oxidation reduction
206806_at	0.222	3.698	2.991	9.035e-03	0.341	-2.541	DGKI	diacylglycerol kinase, iota	7	-136724924	NM_004717	9162	7q32.3-q33	Hs.242947	6	nucleotide binding diacylglycerol kinase activity protein binding ATP binding nucleus cytoplasm activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway intracellular signaling cascade zinc ion binding transferase activity metal ion binding	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phosphatidylinositol signaling system
224796_at	0.341	6.708	2.990	9.050e-03	0.341	-2.543	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	8	-131133534	W03103	50807	8q24.1-q24.2	Hs.655552	19	protein binding cytoplasm ARF GTPase activator activity zinc ion binding membrane regulation of ARF GTPase activity metal ion binding	Endocytosis Fc gamma R-mediated phagocytosis
226649_at	-0.367	7.435	-2.989	9.057e-03	0.341	-2.543	PANK1	pantothenate kinase 1	10	-91332728, -91332728	AI373299	53354	10q23.31	Hs.715502	10	nucleotide binding pantothenate kinase activity pantothenate kinase activity ATP binding cytoplasm cytosol coenzyme A biosynthetic process transferase activity	Pantothenate and CoA biosynthesis Metabolic pathways
234071_at	-0.345	3.755	-2.988	9.089e-03	0.342	-2.547	DEPDC6	DEP domain containing 6	8	120955080	AU147969	64798	8q24.12	Hs.112981	11	protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size
228189_at	-0.408	6.760	-2.987	9.096e-03	0.342	-2.547	BAG4	BCL2-associated athanogene 4	8	38153262	T32429	9530	8p11.23	Hs.194726	14	receptor signaling protein activity protein binding cytoplasm protein folding apoptosis anti-apoptosis
214106_s_at	0.395	5.044	2.987	9.099e-03	0.342	-2.548	GMDS	GDP-mannose 4,6-dehydratase	6	-1569039	AI762113	2762	6p25	Hs.144496 Hs.660919	11	binding intracellular cytoplasm carbohydrate metabolic process leukocyte adhesion GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process cellular metabolic process coenzyme binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
220667_at	-0.242	3.056	-2.985	9.130e-03	0.343	-2.551	USP49	ubiquitin specific peptidase 49	6	-41873360	NM_018540	25862	6p21	Hs.665742	5	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding
238315_s_at	0.402	3.990	2.985	9.142e-03	0.343	-2.552	ZNF567	zinc finger protein 567	19	41872141	BF061829	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218728_s_at	0.464	7.655	2.984	9.150e-03	0.343	-2.552	CNIH4	cornichon homolog 4 (Drosophila)	1	222611217	NM_014184	29097	1q42.11	Hs.195403 Hs.445890	11	protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane
235146_at	0.644	7.179	2.984	9.151e-03	0.343	-2.553	TMCC3	transmembrane and coiled-coil domain family 3	12	-93485030	N51717	57458	12q22	Hs.370410	5	membrane integral to membrane
231403_at	0.365	6.017	2.983	9.168e-03	0.343	-2.554	TRIO	triple functional domain (PTPRF interacting)	5	14196828	N21108	7204	5p15.2	Hs.130031	22	nucleotide binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity ATP binding intracellular cytoplasm protein amino acid phosphorylation transmembrane receptor protein tyrosine phosphatase signaling pathway transferase activity regulation of Rho protein signal transduction
212731_at	-0.499	8.864	-2.983	9.174e-03	0.343	-2.555	ANKRD46	ankyrin repeat domain 46	8	-101602175	U79297	157567	8q22.2	Hs.530199	5	membrane integral to membrane
228039_at	-0.433	7.700	-2.982	9.186e-03	0.343	-2.556	DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	5	134122359	AI765169	9879	5q31.1	Hs.406549	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing Cajal body nuclear speck hydrolase activity
225273_at	0.406	6.123	2.980	9.229e-03	0.345	-2.560	WWC3	WWC family member 3	X	9943794	AB033106	55841	Xp22.32	Hs.527524	5
232266_x_at	0.325	8.553	2.979	9.251e-03	0.345	-2.562	CDC2L5	cell division cycle 2-like 5 (cholinesterase-related cell division controller)	7	39956483	AK024379	8621	7p13	Hs.233552	18	nucleotide binding cyclin-dependent protein kinase activity ATP binding protein amino acid phosphorylation regulation of mitosis multicellular organismal development positive regulation of cell proliferation transferase activity
233884_at	0.566	4.537	2.978	9.268e-03	0.345	-2.564	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	1	-41748270	AL512747	59269	1p34	Hs.648369 Hs.715958	12	DNA binding intracellular nucleus cytoplasm zinc ion binding transcription activator activity positive regulation of transcription metal ion binding
215620_at	0.401	5.033	2.978	9.274e-03	0.345	-2.565	RREB1	ras responsive element binding protein 1	6	7053186	AU147182	6239	6p25	Hs.298248	13	DNA binding intracellular nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter Ras protein signal transduction multicellular organismal development zinc ion binding transcription activator activity nuclear speck metal ion binding
233813_at	0.507	4.567	2.977	9.287e-03	0.345	-2.566	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AK026900	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
203763_at	0.357	5.435	2.977	9.290e-03	0.345	-2.566	DYNC2LI1	dynein, cytoplasmic 2, light intermediate chain 1	2	43854685, 43854685, 43854685	NM_016008	51626	2p25.1-p24.1	Hs.371597	7	motor activity cytoplasm microtubule cilium multicellular organismal development determination of left/right symmetry cell projection organization dynein complex cilium axoneme cilium assembly
239918_at	-0.216	5.589	-2.977	9.294e-03	0.345	-2.566	PVR	poliovirus receptor	19	49838937, 49838937	AI139114	5817	19q13.2	Hs.171844	46	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target receptor activity extracellular region extracellular space cytoplasm plasma membrane plasma membrane cell adhesion cell surface integral to membrane susceptibility to natural killer cell mediated cytotoxicity interspecies interaction between organisms cell adhesion molecule binding susceptibility to T cell mediated cytotoxicity	Cell adhesion molecules (CAMs)
212567_s_at	-0.331	8.340	-2.977	9.294e-03	0.345	-2.566	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AL523310	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
230619_at	-0.255	6.369	-2.976	9.309e-03	0.345	-2.568	ARNT	aryl hydrocarbon receptor nuclear translocator	1	-149048809	AI768497	405	1q21	Hs.632446	88	response to hypoxia positive regulation of endothelial cell proliferation RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus regulation of transcription, DNA-dependent signal transduction positive regulation vascular endothelial growth factor production aryl hydrocarbon receptor binding positive regulation of vascular endothelial growth factor receptor signaling pathway mRNA transcription from RNA polymerase II promoter positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of glycolysis positive regulation of hormone biosynthetic process protein heterodimerization activity	Pathways in cancer Renal cell carcinoma
240061_at	0.591	4.293	2.976	9.309e-03	0.345	-2.568	PION	pigeon homolog (Drosophila)	7	-76778003	AW664903	54103	7q11.23	Hs.186649	4
1562581_at	0.324	4.926	2.974	9.342e-03	0.346	-2.571	LOC254028	hypothetical LOC254028	14		AK093210	254028	14q11.2	Hs.652569	2
1559870_at	0.290	5.947	2.973	9.361e-03	0.346	-2.573	LOC100129129	hypothetical protein LOC100129129	8		BC038546	100129129	8p23.1	Hs.662094
208583_x_at	-0.224	6.372	-2.973	9.366e-03	0.346	-2.573	HIST1H2AJ	histone cluster 1, H2aj	6	-27890058	NM_021066	8331	6p22-p21.3	Hs.406691	10		Systemic lupus erythematosus
212588_at	0.507	4.854	2.972	9.378e-03	0.346	-2.574	PTPRC	protein tyrosine phosphatase, receptor type, C	1	196874759, 196874759	Y00062	5788	1q31-q32	Hs.654514	174	negative regulation of T cell mediated cytotoxicity negative regulation of cytokine-mediated signaling pathway immunoglobulin biosynthetic process transmembrane receptor protein tyrosine phosphatase activity protein binding plasma membrane integral to plasma membrane focal adhesion negative regulation of protein kinase activity negative regulation of protein kinase activity protein amino acid dephosphorylation cell surface receptor linked signal transduction hydrolase activity protein kinase binding T cell differentiation positive regulation of B cell proliferation regulation of S phase positive regulation of T cell proliferation positive regulation of protein kinase activity T cell receptor signaling pathway B cell receptor signaling pathway positive regulation of antigen receptor-mediated signaling pathway release of sequestered calcium ion into cytosol defense response to virus regulation of cell cycle	Cell adhesion molecules (CAMs) T cell receptor signaling pathway Fc gamma R-mediated phagocytosis Primary immunodeficiency
207180_s_at	-0.304	7.429	-2.970	9.418e-03	0.346	-2.578	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	NM_006410	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
225161_at	-0.429	7.141	-2.970	9.426e-03	0.346	-2.579	GFM1	G elongation factor, mitochondrial 1	3	159845010	AI659020	85476	3q25.1-q26.2	Hs.518355	11	nucleotide binding translation elongation factor activity GTPase activity GTP binding intracellular mitochondrion translational elongation
203524_s_at	0.459	7.661	2.970	9.427e-03	0.346	-2.579	MPST	mercaptopyruvate sulfurtransferase	22	35745647	NM_021126	4357	22q13.1	Hs.248267	9	thiosulfate sulfurtransferase activity cytoplasm mitochondrion sulfate transport cyanate catabolic process response to toxin transferase activity 3-mercaptopyruvate sulfurtransferase activity	Cysteine and methionine metabolism Metabolic pathways
1553071_a_at	-0.721	6.578	-2.970	9.427e-03	0.346	-2.579	MYOZ3	myozenin 3	5	150020596	NM_133371	91977	5q33.1	Hs.91626	7	protein binding cytoplasm Z disc
236954_at	-0.352	5.249	-2.970	9.429e-03	0.346	-2.579	BOLL	bol, boule-like (Drosophila)	2	-198299847, -198299847	BF059752	66037	2q33	Hs.169797	16	nucleotide binding RNA binding protein binding cytoplasm regulation of translation meiosis multicellular organismal development spermatogenesis translation activator activity cell differentiation positive regulation of translational initiation
231260_at	0.350	3.911	2.969	9.439e-03	0.346	-2.580	BC036928	hypothetical protein BC036928	19		AW162207	386758	19q13.43	Hs.549564	1
227792_at	-0.323	7.361	-2.968	9.465e-03	0.347	-2.583	ITPRIPL2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	16	19032754	AA490685	162073	16p12.3	Hs.530899 Hs.648523	3	membrane integral to membrane
201160_s_at	-0.226	12.837	-2.967	9.474e-03	0.347	-2.584	CSDA	cold shock domain protein A	12	-10742944	AL556190	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
213587_s_at	0.423	6.317	2.967	9.482e-03	0.347	-2.584	ATP6V0E2	ATPase, H+ transporting V0 subunit e2	7	149200989, 149200989	AI884867	155066	7q36.1	Hs.556998 Hs.698060	5	ion transport vacuolar acidification hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport membrane integral to membrane cell growth hydrolase activity proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions	Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
201238_s_at	-0.517	10.394	-2.967	9.484e-03	0.347	-2.585	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	7	116289798	BC005338	830	7q31.2-q31.3	Hs.446123	14	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
202144_s_at	-0.453	9.944	-2.967	9.488e-03	0.347	-2.585	ADSL	adenylosuccinate lyase	22	39072449	NM_000026	158	22q13.1 22q13.2	Hs.75527	29	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity cytoplasm cytosol AMP biosynthetic process purine ribonucleotide biosynthetic process lyase activity protein tetramerization (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
201791_s_at	0.259	5.806	2.965	9.517e-03	0.347	-2.588	DHCR7	7-dehydrocholesterol reductase	11	-70823104	NM_001360	1717	11q13.2-q13.5	Hs.503134	48	blood vessel development protein binding nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane cholesterol biosynthetic process post-embryonic development membrane integral to membrane oxidoreductase activity cell differentiation lung development multicellular organism growth regulation of cell proliferation 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity oxidation reduction	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
1558077_s_at	0.244	4.430	2.963	9.553e-03	0.348	-2.591	MDH1B	malate dehydrogenase 1B, NAD (soluble)	2	-207310733	BG202523	130752	2q33.3	Hs.147816	1	binding carbohydrate metabolic process tricarboxylic acid cycle malate metabolic process oxidoreductase activity malate dehydrogenase activity oxidation reduction
223229_at	-0.471	6.718	-2.963	9.556e-03	0.348	-2.591	UBE2T	ubiquitin-conjugating enzyme E2T (putative)	1	-200567408	AB032931	29089	1q32.1	Hs.5199	10	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
222389_s_at	-0.268	7.428	-2.963	9.561e-03	0.348	-2.592	WAC	WW domain containing adaptor with coiled-coil	10	28861432, 28862429	BE879807	51322		Hs.714700	15	protein binding nucleus nuclear speck
225793_at	-0.405	7.860	-2.962	9.581e-03	0.348	-2.594	LIX1L	Lix1 homolog (mouse)-like	1	144188441	AW500180	128077	1q21.1	Hs.632435	2
230137_at	-0.261	4.321	-2.962	9.585e-03	0.348	-2.594	TMEM155	transmembrane protein 155	4	-122899534	BF673779	132332	4q27	Hs.27524 Hs.607691	5	extracellular region
234192_s_at	-0.463	8.574	-2.961	9.598e-03	0.348	-2.595	GKAP1	G kinase anchoring protein 1	9	-85544156	AK026487	80318	9q21.32	Hs.522255	5	protein binding Golgi apparatus signal transduction
230524_at	0.245	4.328	2.961	9.599e-03	0.348	-2.595	MPI	mannose phosphate isomerase	15	72969462	AA973383	4351	15q22-qter	Hs.75694	18	mannose-6-phosphate isomerase activity cytoplasm carbohydrate metabolic process zinc ion binding isomerase activity metal ion binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
229534_at	0.381	4.631	2.961	9.606e-03	0.348	-2.596	ACOT4	acyl-CoA thioesterase 4	14	73128162	AA046424	122970	14q24.3	Hs.49433	10	very-long-chain fatty acid metabolic process carboxylesterase activity peroxisome succinyl-CoA metabolic process lipid metabolic process acyl-CoA metabolic process palmitoyl-CoA hydrolase activity hydrolase activity thiolester hydrolase activity saturated monocarboxylic acid metabolic process unsaturated monocarboxylic acid metabolic process butanoic acid metabolic process dicarboxylic acid metabolic process	Biosynthesis of unsaturated fatty acids
202474_s_at	-0.254	7.695	-2.960	9.621e-03	0.348	-2.597	HCFC1	host cell factor C1 (VP16-accessory protein)	X	-152866201	NM_005334	3054	Xq28	Hs.83634	53	transcription factor activity transcription coactivator activity nucleus cytoplasm transcription from RNA polymerase II promoter reactivation of latent virus identical protein binding regulation of protein complex assembly regulation of transcription positive regulation of cell cycle MLL5-L complex
229222_at	0.531	6.266	2.959	9.632e-03	0.348	-2.598	ACSS3	acyl-CoA synthetase short-chain family member 3	12	79995939	AI123815	79611	12q21.31	Hs.259559	2	nucleotide binding acetate-CoA ligase activity ATP binding mitochondrion metabolic process ligase activity	Propanoate metabolism Metabolic pathways
229110_at	0.741	3.472	2.958	9.650e-03	0.348	-2.600	LOC100128844	hypothetical protein LOC100128844	9		N50083	100128844	9p22.1	Hs.593150
235199_at	0.717	5.278	2.958	9.663e-03	0.348	-2.601	RNF125	ring finger protein 125	18	27852442	AI969697	54941	18q12.1	Hs.633703	10	protein binding intracellular immune response zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	RIG-I-like receptor signaling pathway
214704_at	0.242	4.378	2.958	9.664e-03	0.348	-2.601	TCF25	transcription factor 25 (basic helix-loop-helix)	16	88467494	AK024679	22980	16q24.3	Hs.415342	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus heart development regulation of transcription
221637_s_at	0.316	7.056	2.957	9.678e-03	0.348	-2.603	C11orf48	chromosome 11 open reading frame 48	11	-62186864	BC001434	79081	11q12.3	Hs.9061	3
222437_s_at	-0.337	9.163	-2.956	9.689e-03	0.348	-2.604	VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	2	-86584063	BC004419	51652	2p24.3-p24.1	Hs.591582	25	protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division	Endocytosis
212678_at	-0.280	5.639	-2.955	9.716e-03	0.348	-2.606	NF1	neurofibromin 1	17	26446120, 26446120	AW054826	4763	17q11.2	Hs.113577	204	osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction	MAPK signaling pathway
215895_x_at	0.259	3.327	2.955	9.720e-03	0.348	-2.606	PLIN2	perilipin 2	9	-19105758	AK022061	123	9p22.1	Hs.3416	31	protein binding extracellular region nucleus cytoplasm endoplasmic reticulum lipid particle plasma membrane long-chain fatty acid transport lipid storage
205444_at	-1.400	10.528	-2.954	9.743e-03	0.348	-2.609	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	16	28797309	NM_004320	487	16p12.1	Hs.657344	41	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding protein binding ATP binding microsome ATP biosynthetic process cation transport metabolic process apoptotic mitochondrial changes membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances positive regulation of fast-twitch skeletal muscle fiber contraction elevation of endoplasmic reticulum calcium ion concentration reduction of endoplasmic reticulum calcium ion concentration sarcoplasmic reticulum membrane sarcoplasmic reticulum membrane calcium channel complex response to endoplasmic reticulum stress protein homodimerization activity elevation of mitochondrial calcium ion concentration maintenance of mitochondrion location apoptosis in response to endoplasmic reticulum stress calcium ion import	Calcium signaling pathway Alzheimer's disease
1555522_s_at	-0.398	7.572	-2.954	9.744e-03	0.348	-2.609	MEMO1	mediator of cell motility 1	2	-31946398, -31946397	BC036262	51072	2p22-p21	Hs.444969	10	nucleus cytosol
218455_at	0.380	6.681	2.953	9.747e-03	0.348	-2.609	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	20	-33720024	NM_021100	9054	20q11.22	Hs.194692	14	protein binding nucleus cytoplasm mitochondrion mitochondrial matrix cytosol protein complex assembly cysteine metabolic process Mo-molybdopterin cofactor biosynthetic process metabolic process transferase activity iron incorporation into metallo-sulfur cluster pyridoxal phosphate binding cysteine desulfurase activity protein homodimerization activity	Thiamine metabolism
210852_s_at	0.332	4.575	2.952	9.781e-03	0.349	-2.612	AASS	aminoadipate-semialdehyde synthase	7	-121500835	AF229180	10157	7q31.3	Hs.156738	10	binding mitochondrion electron carrier activity oxidoreductase activity L-lysine catabolic process saccharopine dehydrogenase (NADP+, L-lysine-forming) activity saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity protein tetramerization oxidation reduction	Lysine biosynthesis Lysine degradation Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
222859_s_at	0.474	4.120	2.952	9.781e-03	0.349	-2.612	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	AA150186	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
1556283_s_at	-0.319	4.937	-2.951	9.786e-03	0.349	-2.613	FGFR1OP2	FGFR1 oncogene partner 2	12	26982582	W74643	26127	12p11.23	Hs.591162	5	cytoplasm
231798_at	0.652	5.036	2.951	9.795e-03	0.349	-2.613	NOG	noggin	17	52026058	AL575177	9241	17q21-q22	Hs.248201	48	osteoblast differentiation ureteric bud development epithelial to mesenchymal transition extracellular region extracellular region extracellular space pattern specification process brain development dorsal/ventral pattern formation cytokine binding negative regulation of BMP signaling pathway prostate gland development somatic stem cell maintenance wound healing middle ear morphogenesis embryonic digit morphogenesis protein homodimerization activity negative regulation of cell differentiation notochord morphogenesis anatomical structure formation involved in morphogenesis embryonic skeletal system development negative regulation of astrocyte differentiation mesenchymal cell differentiation positive regulation of epithelial cell proliferation cartilage development negative regulation of cardiac muscle cell proliferation limb development embryonic skeletal joint morphogenesis negative regulation of cytokine activity	TGF-beta signaling pathway
221270_s_at	0.323	6.081	2.950	9.810e-03	0.349	-2.615	QTRT1	queuine tRNA-ribosyltransferase 1	19	10673111	NM_031209	81890	19p13.3	Hs.631638	7	ribosome zinc ion binding queuine tRNA-ribosyltransferase activity queuine tRNA-ribosyltransferase activity queuosine biosynthetic process queuosine biosynthetic process transferase activity, transferring glycosyl groups metal ion binding
240310_at	-0.463	5.372	-2.950	9.817e-03	0.349	-2.615	TOR1AIP1	torsin A interacting protein 1	1	178118042	AI807835	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
201124_at	0.313	5.461	2.950	9.824e-03	0.349	-2.616	ITGB5	integrin, beta 5	3	-125964484	AL048423	3693	3q21.2	Hs.536663	55	receptor activity protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
234367_x_at	0.269	5.286	2.949	9.835e-03	0.349	-2.617	TMPRSS6	transmembrane protease, serine 6	22	-35791424	AL022314	164656	22q12.3	Hs.370885	16	angiogenesis serine-type endopeptidase activity plasma membrane proteolysis intracellular signaling cascade peptidase activity integral to membrane extracellular matrix organization fibrinolysis
235760_at	0.413	5.317	2.948	9.855e-03	0.349	-2.619	NSD1	nuclear receptor binding SET domain protein 1	5	176492685, 176493438	AI421972	64324	5q35.2-q35.3	Hs.106861	36	negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription corepressor activity protein binding nucleus methyltransferase activity zinc ion binding chromatin modification histone methylation transferase activity ligand-dependent nuclear receptor binding estrogen receptor binding histone methyltransferase activity (H4-K20 specific) regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	Lysine degradation
226852_at	0.259	4.750	2.948	9.856e-03	0.349	-2.619	MTA3	metastasis associated 1 family, member 3	2	42649174	AB033092	57504	2p21	Hs.435413	15	transcription factor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
227207_x_at	-0.297	6.302	-2.947	9.876e-03	0.349	-2.621	ZNF213	zinc finger protein 213	16	3125057, 3125134	BF510572	7760	16p13.3	Hs.115284	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
228878_s_at	-0.266	4.612	-2.947	9.879e-03	0.349	-2.621	CFC1B	cripto, FRL-1, cryptic family 1B	2	-131066822, 130995136	BE550131	653275	2q21.1	Hs.503733	1
203824_at	-1.861	8.236	-2.946	9.888e-03	0.349	-2.622	TSPAN8	tetraspanin 8	12	-69805143	NM_004616	7103	12q14.1-q21.1	Hs.170563	23	signal transducer activity lysosome protein amino acid glycosylation membrane integral to membrane
210711_at	0.231	4.589	2.946	9.902e-03	0.349	-2.623	C1orf217	chromosome 1 open reading frame 217	1		BC000988	84719	1q32.1	Hs.661178	1
218769_s_at	0.510	6.523	2.945	9.914e-03	0.349	-2.624	ANKRA2	ankyrin repeat, family A (RFXANK-like), 2	5	-72883918	NM_023039	57763	5q12-q13	Hs.239154	6	protein binding membrane fraction cytoplasm cytosol cytoskeleton biological_process membrane low-density lipoprotein binding
218520_at	-0.390	6.533	-2.945	9.915e-03	0.349	-2.624	TBK1	TANK-binding kinase 1	12	63132203	NM_013254	29110	12q14.1	Hs.505874 Hs.607889	51	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation response to virus transferase activity positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms innate immune response	Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway
209139_s_at	-0.383	9.622	-2.944	9.927e-03	0.349	-2.625	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	2	-179004387, -179004387, -179004387	AF083033	8575	2q31.2	Hs.570274	27	double-stranded RNA binding protein binding intracellular cytoplasm protein amino acid phosphorylation induction of apoptosis response to stress immune response enzyme activator activity negative regulation of cell proliferation response to virus RNA interference, production of siRNA gene silencing by RNA outer ear morphogenesis middle ear morphogenesis protein homodimerization activity perinuclear region of cytoplasm skeletal system morphogenesis
220512_at	0.238	4.901	2.944	9.932e-03	0.349	-2.626	DLC1	deleted in liver cancer 1	8	-13116452, -12985242, -12985242	NM_024767	10395	8p22	Hs.134296	48	neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation
223608_at	0.601	6.228	2.944	9.932e-03	0.349	-2.626	EFCAB2	EF-hand calcium binding domain 2	1	243199793, 243199906, 243200253, 243200253	BC005357	84288	1q44	Hs.134857	5	calcium ion binding
227862_at	0.444	5.362	2.944	9.939e-03	0.349	-2.626	TRNP1	TMF1-regulated nuclear protein 1	1	27192781	AA037766	388610	1p36.11	Hs.355747	2	nucleus cell cycle
234018_s_at	-0.936	4.316	-2.942	9.975e-03	0.350	-2.630	SEL1L2	sel-1 suppressor of lin-12-like 2 (C. elegans)	20	-13778049	AL137678	80343	20p12.1	Hs.590879	1	binding membrane integral to membrane
235721_at	0.248	6.811	2.941	9.994e-03	0.350	-2.631	DTX3	deltex homolog 3 (Drosophila)	12	56284870	N62126	196403	12q13.3	Hs.32374	6	protein binding cytoplasm Notch signaling pathway zinc ion binding metal ion binding	Notch signaling pathway
1554510_s_at	-0.371	9.923	-2.940	1.003e-02	0.351	-2.634	GHITM	growth hormone inducible transmembrane protein	10	85889164	AB009685	27069	10q23.1	Hs.352656	15	molecular_function biological_process membrane integral to membrane
41577_at	0.392	5.424	2.940	1.003e-02	0.351	-2.634	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AB020630	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
202716_at	-0.286	6.465	-2.940	1.003e-02	0.351	-2.634	PTPN1	protein tyrosine phosphatase, non-receptor type 1	20	48560297	NM_002827	5770	20q13.1-q13.2	Hs.417549	144	protein tyrosine phosphatase activity protein binding endoplasmic reticulum protein amino acid dephosphorylation signal transduction zinc ion binding membrane hydrolase activity negative regulation of insulin receptor signaling pathway	Adherens junction Insulin signaling pathway
1557132_at	0.211	2.251	2.939	1.004e-02	0.351	-2.635	WDR17	WD repeat domain 17	4	177224125	BI713506	116966	4q34	Hs.532056	3
214065_s_at	0.268	4.956	2.938	1.006e-02	0.351	-2.637	CIB2	calcium and integrin binding family member 2	15	-76184045	BG251252	10518	15q24	Hs.129867	6	calcium ion binding protein binding
222125_s_at	0.280	6.465	2.938	1.007e-02	0.351	-2.638	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	3	49002344	BC000580	54681	3p21.31	Hs.654944	9	iron ion binding calcium ion binding endoplasmic reticulum membrane integral to membrane oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding oxidation reduction
202732_at	0.314	8.196	2.937	1.008e-02	0.351	-2.639	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	20	42593849	NM_007066	11142	20q12-q13.1	Hs.472831	9	negative regulation of transcription from RNA polymerase II promoter protein kinase inhibitor activity cAMP-dependent protein kinase inhibitor activity protein binding soluble fraction negative regulation of protein kinase activity negative regulation of protein import into nucleus
222827_s_at	-1.152	11.393	-2.936	1.011e-02	0.352	-2.641	KBTBD10	kelch repeat and BTB (POZ) domain containing 10	2	170074457	AI126808	10324	2q31.1	Hs.50550	8	ruffle protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion striated muscle contraction modification-dependent protein catabolic process pseudopodium
1560445_x_at	0.308	6.213	2.935	1.011e-02	0.352	-2.642	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	19	47079106, 47080285	AK026781	9138	19q13.13	Hs.631550	29	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm cytosol plasma membrane plasma membrane cell proliferation regulation of Rho protein signal transduction	Vascular smooth muscle contraction Regulation of actin cytoskeleton
231437_at	0.250	4.973	2.935	1.012e-02	0.352	-2.643	SLC35D2	solute carrier family 35, member D2	9	-98122809	AA693722	11046	9q22.32	Hs.494556	6	nucleotide-sugar transmembrane transporter activity cellular_component Golgi apparatus biological_process carbohydrate transport membrane integral to membrane
210257_x_at	-0.357	4.790	-2.935	1.013e-02	0.352	-2.643	CUL4B	cullin 4B	X	-119542473, -119542473	AF212995	8450	Xq23	Hs.102914	28	molecular_function protein binding cellular_component DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
1558140_at	-0.251	4.242	-2.934	1.014e-02	0.352	-2.644	PLXNA1	plexin A1	3	128190191	X87832	5361	3q21.3	Hs.432329	18	receptor activity protein binding cellular_component intracellular membrane fraction signal transduction multicellular organismal development membrane integral to membrane semaphorin receptor activity	Axon guidance
209675_s_at	0.218	6.030	2.934	1.014e-02	0.352	-2.645	HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	19	46460230, 46461959	BC004242	11100	19q13.2	Hs.155218 Hs.718642	26	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus RNA processing response to virus heterogeneous nuclear ribonucleoprotein complex regulation of transcription
205021_s_at	0.298	6.755	2.934	1.015e-02	0.352	-2.645	FOXN3	forkhead box N3	14	-88692268, -88692268	AA860806	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
244655_at	0.476	4.113	2.934	1.015e-02	0.352	-2.645	LOC100132798	similar to hCG1774772	15		W68045	100132798	15q26.2
228561_at	-0.647	6.687	-2.933	1.016e-02	0.352	-2.646	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	9	4669565	BF510563	55664	9p24.1	Hs.561954	6	protein binding cytoplasm
208159_x_at	0.521	6.452	2.933	1.016e-02	0.352	-2.646	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	12	31118045	NM_004399	1663	12p11	Hs.443960	13	mitotic sister chromatid segregation S phase of mitotic cell cycle G2/M transition of mitotic cell cycle nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP binding nucleus nucleolus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle positive regulation of cell proliferation hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
214266_s_at	-0.493	7.183	-2.931	1.021e-02	0.352	-2.650	PDLIM7	PDZ and LIM domain 7 (enigma)	5	-176849852, -176843000	AW206786	9260	5q35.3	Hs.533040	22	ossification protein binding cytoplasm cytoskeleton receptor-mediated endocytosis multicellular organismal development zinc ion binding cell differentiation metal ion binding
1564299_at	-0.257	3.053	-2.930	1.022e-02	0.352	-2.651	LOC100127940	hypothetical LOC100127940	7		AK090626	100127940	7p22.3	Hs.638549	1
236831_at	-0.431	4.498	-2.930	1.023e-02	0.352	-2.652	CCDC50	coiled-coil domain containing 50	3	192529567	AV683852	152137	3q28	Hs.478682	12	protein binding cytoplasm
211212_s_at	-0.513	4.231	-2.929	1.024e-02	0.352	-2.653	ORC5L	origin recognition complex, subunit 5-like (yeast)	7	-103595859, -103554023	AF081459	5001	7q22.1	Hs.432948	28	nucleotide binding DNA replication origin binding ATP binding nucleus nucleoplasm DNA replication DNA replication DNA replication initiation identical protein binding	Cell cycle
1558166_at	0.272	3.666	2.929	1.024e-02	0.352	-2.653	MGC16275	hypothetical protein MGC16275	17	-69717735	BM824870	85001	17q25.1	Hs.706954	1
201375_s_at	-0.310	10.090	-2.929	1.025e-02	0.352	-2.654	PPP2CB	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	8	-30762667	NM_004156	5516	8p12	Hs.491440	40	protein phosphatase type 2A complex chromosome, centromeric region protein serine/threonine phosphatase activity iron ion binding protein binding nucleus cytoplasm spindle protein amino acid dephosphorylation regulation of gene expression hydrolase activity manganese ion binding response to hydrogen peroxide negative regulation of apoptosis proteasomal ubiquitin-dependent protein catabolic process response to antibiotic metal ion binding	Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression
1565786_x_at	0.434	5.202	2.929	1.026e-02	0.352	-2.654	FLJ45482	hypothetical LOC645566	7		BQ953917	645566		Hs.644332	1
200830_at	-0.267	9.581	-2.928	1.028e-02	0.352	-2.656	PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	3	185499715	NM_002808	5708	3q27.1	Hs.518464	45	proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
222636_at	-0.306	4.772	-2.927	1.028e-02	0.352	-2.656	MED28	mediator complex subunit 28	4	17225370	AF317680	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
217183_at	0.214	5.383	2.927	1.028e-02	0.352	-2.657	LDLR	low density lipoprotein receptor	19	11061056	S70123	3949	19p13.3	Hs.213289 Hs.713967	374	transmembrane receptor activity low-density lipoprotein receptor activity calcium ion binding endosome plasma membrane plasma membrane integral to plasma membrane coated pit protein amino acid O-linked glycosylation lipid metabolic process lipid transport endocytosis steroid metabolic process cholesterol metabolic process endosome membrane very-low-density lipoprotein receptor activity intestinal cholesterol absorption clathrin-coated endocytic vesicle membrane low-density lipoprotein particle low-density lipoprotein particle clearance lipoprotein catabolic process cholesterol homeostasis interspecies interaction between organisms	Endocytosis
207996_s_at	-0.735	6.652	-2.927	1.029e-02	0.352	-2.657	C18orf1	chromosome 18 open reading frame 1	18	13208785, 13601664, 13610866	NM_004338	753	18p11.2	Hs.149363	9	molecular_function plasma membrane biological_process integral to membrane
1558828_s_at	0.418	5.178	2.926	1.030e-02	0.352	-2.658	LOC728264	hypothetical LOC728264	5	148766632	AL703532	728264	5q32	Hs.519666	1
242750_at	0.431	6.155	2.926	1.031e-02	0.352	-2.659	MMAA	methylmalonic aciduria (cobalamin deficiency) cblA type	4	146759989	AA678047	166785	4q31.21	Hs.452864	10	nucleotide binding ATP binding mitochondrion nucleoside-triphosphatase activity
219455_at	-0.299	5.015	-2.926	1.032e-02	0.352	-2.660	C7orf63	chromosome 7 open reading frame 63	7	89712423	NM_024788	79846	7q21.13	Hs.657403	4	binding
206853_s_at	-0.279	6.486	-2.925	1.032e-02	0.352	-2.660	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AL121964	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
204822_at	0.195	2.579	2.925	1.033e-02	0.352	-2.660	TTK	TTK protein kinase	6	80771077	NM_003318	7272	6q13-q21	Hs.169840	33	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding spindle protein amino acid phosphorylation mitotic spindle organization mitotic cell cycle spindle assembly checkpoint positive regulation of cell proliferation positive regulation of pathway-restricted SMAD protein phosphorylation transferase activity	Cell cycle
232207_at	-0.367	5.575	-2.925	1.034e-02	0.352	-2.661	GUSBL2	glucuronidase, beta-like 2	6	-58354117	AK026691	375513	6p11.2	Hs.561539 Hs.711053	5
203570_at	0.651	4.863	2.924	1.034e-02	0.352	-2.662	LOXL1	lysyl oxidase-like 1	15	72005841	NM_005576	4016	15q22 15q24-q25	Hs.65436	48	copper ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space oxidoreductase activity oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor protein amino acid deamination metal ion binding oxidation reduction
225919_s_at	-0.345	5.703	-2.924	1.035e-02	0.352	-2.662	C9orf72	chromosome 9 open reading frame 72	9	-27550498, -27536543	AI832598	203228	9p21.2	Hs.493639	4
209146_at	0.448	5.459	2.924	1.035e-02	0.352	-2.663	SC4MOL	sterol-C4-methyl oxidase-like	4	166468267	AV704962	6307	4q32-q34	Hs.105269 Hs.593050	5	C-4 methylsterol oxidase activity C-4 methylsterol oxidase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane plasma membrane fatty acid biosynthetic process integral to membrane sterol biosynthetic process oxidoreductase activity oxidation reduction	Steroid biosynthesis Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways
228588_s_at	-0.519	9.960	-2.924	1.035e-02	0.352	-2.663	UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	5	133734768	AI499236	7320	5q23-q31	Hs.615284 Hs.644421	23	nucleotide binding protein polyubiquitination chromatin ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus replication fork cytoplasm plasma membrane postreplication repair postreplication repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein monoubiquitination response to DNA damage stimulus spermatogenesis sperm axoneme assembly response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination response to drug protein stabilization regulation of protein metabolic process protein autoubiquitination Wnt receptor signaling pathway through beta-catenin	Ubiquitin mediated proteolysis
226590_at	0.371	5.294	2.923	1.036e-02	0.352	-2.664	ZNF618	zinc finger protein 618	9	115678382	AA910497	114991	9q32	Hs.349208	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity
226066_at	-0.359	8.536	-2.923	1.038e-02	0.352	-2.665	MITF	microphthalmia-associated transcription factor	3	69871322, 69895651, 69998131, 70010945, 70068442	AL117653	4286	3p14.2-p14.1	Hs.166017 Hs.618266	93	DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation	Melanogenesis Pathways in cancer Melanoma
235953_at	0.505	4.455	2.922	1.038e-02	0.352	-2.665	ZNF610	zinc finger protein 610	19	57531309, 57540493	AA776810	162963	19q13.41	Hs.357663	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
215590_x_at	-0.414	6.356	-2.922	1.038e-02	0.352	-2.665	LOC100128640	hypothetical protein LOC100128640	3		AK025619	100128640	3p22.2
219892_at	-0.725	7.987	-2.922	1.039e-02	0.352	-2.666	TM6SF1	transmembrane 6 superfamily member 1	15	81567327	NM_023003	53346	15q24-q26	Hs.513094	4	molecular_function biological_process membrane integral to membrane
225606_at	0.593	6.832	2.921	1.041e-02	0.352	-2.668	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2	111594961, 111594961	AI949179	10018	2q13	Hs.469658	143	peripheral to membrane of membrane fraction in utero embryonic development B cell homeostasis B cell apoptosis kidney development myeloid cell homeostasis protein binding cytoplasm mitochondrion mitochondrial outer membrane cytosol plasma membrane induction of apoptosis cell-matrix adhesion spermatogenesis microtubule binding male gonad development activation of pro-apoptotic gene products post-embryonic development mammary gland development tube lumen formation odontogenesis of dentine-containing tooth T cell homeostasis ear development regulation of organ growth regulation of pigmentation during development spleen development thymus development post-embryonic organ morphogenesis
214493_s_at	-0.452	4.578	-2.921	1.042e-02	0.352	-2.668	INADL	InaD-like (Drosophila)	1	61980736	NM_005799	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
218404_at	0.518	4.568	2.921	1.042e-02	0.352	-2.669	SNX10	sorting nexin 10	7	26298039	NM_013322	29887	7p15.2	Hs.719227	6	protein binding cell communication protein transport phosphoinositide binding
227674_at	0.379	5.421	2.920	1.043e-02	0.352	-2.669	ZNF585A	zinc finger protein 585A	19	-42332840, -42332840	AA910852	199704	19q13.12	Hs.390568 Hs.659236	3	nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210976_s_at	-0.502	12.191	-2.920	1.043e-02	0.352	-2.669	PFKM	phosphofructokinase, muscle	12	46799294	U24183	5213	12q13.3	Hs.75160	35	nucleotide binding magnesium ion binding 6-phosphofructokinase activity 6-phosphofructokinase activity 6-phosphofructokinase activity ATP binding sugar binding soluble fraction cytoplasm cytosol cytosol 6-phosphofructokinase complex fructose 6-phosphate metabolic process glycolysis protein C-terminus binding kinase activity apical plasma membrane transferase activity kinase binding fructose 1,6-bisphosphate metabolic process positive regulation of insulin secretion glucose homeostasis identical protein binding muscle maintenance protein oligomerization fructose-6-phosphate binding	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Galactose metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
235792_x_at	0.312	5.251	2.920	1.044e-02	0.352	-2.670	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide	11	-17064699	AU154663	5286	11p15.5-p14	Hs.175343	39	nucleotide binding inositol or phosphatidylinositol kinase activity protein binding ATP binding nucleus cytoplasm Golgi apparatus plasma membrane phosphoinositide 3-kinase complex phosphatidylinositol biosynthetic process cell communication 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor clathrin-coated vesicle cytoplasmic vesicle phosphatidylinositol-4-phosphate 3-kinase activity phosphoinositide binding phosphoinositide phosphorylation phosphoinositide-mediated signaling	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
236870_at	0.296	2.543	2.920	1.044e-02	0.352	-2.670	IQCF3	IQ motif containing F3	3	51837608	AW958766	401067	3p21.2	Hs.254808	2
205621_at	-0.283	6.865	-2.920	1.045e-02	0.352	-2.671	ALKBH1	alkB, alkylation repair homolog 1 (E. coli)	14	-77208501	NM_006020	8846	14q24.3	Hs.94542	6	DNA dealkylation
203458_at	-0.522	7.972	-2.918	1.047e-02	0.352	-2.673	SPR	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)	2	72968019	AI951454	6697	2p14-p12	Hs.301540	23	aldo-keto reductase activity sepiapterin reductase activity binding cytoplasm tetrahydrobiopterin biosynthetic process nitric oxide biosynthetic process oxidoreductase activity NADP or NADPH binding oxidation reduction	Folate biosynthesis Metabolic pathways
201534_s_at	-0.438	7.049	-2.918	1.047e-02	0.352	-2.673	UBL3	ubiquitin-like 3	13	-29236545	AF044221	5412	13q12-q13	Hs.145575	12	intracellular plasma membrane
1555906_s_at	-0.630	6.472	-2.917	1.050e-02	0.352	-2.675	C3orf23	chromosome 3 open reading frame 23	3	44354614, 44354947, 44354947	AI147556	285343	3p21.31	Hs.55131	8	mitochondrion
223271_s_at	-0.373	5.914	-2.917	1.051e-02	0.352	-2.676	CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2	15	42506870	AF161543	51496	15q15.3-q21.1	Hs.497967	4	phosphoprotein phosphatase activity hydrolase activity
1568644_at	0.251	2.618	2.916	1.052e-02	0.352	-2.677	ZNF208	zinc finger protein 208	19	-21940736	BC038199	7757	19p12	Hs.541334	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210544_s_at	-0.430	6.810	-2.916	1.053e-02	0.352	-2.678	ALDH3A2	aldehyde dehydrogenase 3 family, member A2	17	19492655, 19492655	BC002430	224	17p11.2	Hs.499886	27	3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity aldehyde dehydrogenase [NAD(P)+] activity mitochondrial inner membrane endoplasmic reticulum cellular aldehyde metabolic process lipid metabolic process central nervous system development peripheral nervous system development epidermis development membrane integral to membrane oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
200627_at	-0.496	10.402	-2.915	1.053e-02	0.352	-2.678	PTGES3	prostaglandin E synthase 3 (cytosolic)	12	-55343391	BC003005	10728	12 12q13.3	Hs.50425	36	telomere maintenance chromosome, telomeric region prostaglandin biosynthetic process telomerase activity telomerase holoenzyme complex cytoplasm fatty acid biosynthetic process signal transduction isomerase activity prostaglandin-E synthase activity unfolded protein binding
241817_at	0.374	3.722	2.915	1.054e-02	0.352	-2.679	C3orf62	chromosome 3 open reading frame 62	3	-49281033	AA729235	375341	3p21.31	Hs.403828	3
222869_s_at	0.446	3.818	2.915	1.055e-02	0.352	-2.679	ELAC1	elaC homolog 1 (E. coli)	18	46748384	AI669235	55520	18q21	Hs.657360	9	endonuclease activity nucleus tRNA processing zinc ion binding hydrolase activity metal ion binding
232740_at	0.253	2.920	2.914	1.056e-02	0.352	-2.680	MCM3APAS	MCM3AP antisense RNA (non-protein coding)	21	46473585	BC002458	114044	21q22.3	Hs.709346	3
202432_at	-0.633	11.048	-2.913	1.058e-02	0.352	-2.682	PPP3CB	protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform	10	-74866569	NM_021132	5532	10q21-q22	Hs.500067	29	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding calcineurin complex signal transduction zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
241859_at	-0.719	5.324	-2.913	1.059e-02	0.352	-2.683	PLCL1	phospholipase C-like 1	2	198377670, 198377777	BF593050	5334	2q33	Hs.153322 Hs.593586	8	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
210347_s_at	0.285	3.668	2.913	1.059e-02	0.352	-2.683	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	2	-60537832, -60531805	AF080216	53335	2p16.1	Hs.370549	26	nucleic acid binding intracellular nucleus cytoplasm zinc ion binding hemopoiesis regulation of transcription metal ion binding
217864_s_at	-0.316	7.683	-2.912	1.060e-02	0.352	-2.684	PIAS1	protein inhibitor of activated STAT, 1	15	66133625	NM_016166	8554	15q	Hs.162458	67	DNA binding transcription coactivator activity transcription corepressor activity nucleus JAK-STAT cascade zinc ion binding nuclear speck SUMO ligase activity enzyme binding modification-dependent protein catabolic process androgen receptor signaling pathway positive regulation of protein sumoylation regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding	Ubiquitin mediated proteolysis Jak-STAT signaling pathway Pathways in cancer Small cell lung cancer
214883_at	-0.227	5.062	-2.912	1.062e-02	0.353	-2.685	THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	17	35472588, 35472685	X55005	7067	17q11.2	Hs.724	95	transcription factor activity steroid hormone receptor activity thyroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter zinc ion binding hormone-mediated signaling regulation of specific transcription from RNA polymerase II promoter promoter binding metal ion binding	Neuroactive ligand-receptor interaction
232704_s_at	-0.387	6.347	-2.911	1.063e-02	0.353	-2.686	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	AK025207	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
219436_s_at	0.407	6.908	2.911	1.063e-02	0.353	-2.686	EMCN	endomucin	4	-101535522	NM_016242	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
238461_at	-0.953	5.652	-2.911	1.063e-02	0.353	-2.687	EIF4E3	eukaryotic translation initiation factor 4E family member 3	3	-71811131, -71811131, -71811131, -71811131	AA228031	317649	3p14	Hs.581355	3	RNA binding translation initiation factor activity cytoplasm translational initiation regulation of translation
207822_at	-0.231	4.483	-2.911	1.064e-02	0.353	-2.687	FGFR1	fibroblast growth factor receptor 1	8	-38400008, -38387812	NM_023107	2260	8p11.2-p11.1	Hs.264887	187	MAPKKK cascade nucleotide binding skeletal system development receptor activity fibroblast growth factor receptor activity fibroblast growth factor receptor activity protein binding ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation heparin binding fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway cell growth transferase activity	MAPK signaling pathway Adherens junction Regulation of actin cytoskeleton Pathways in cancer Prostate cancer Melanoma
225016_at	-0.734	4.994	-2.910	1.065e-02	0.353	-2.688	APCDD1	adenomatosis polyposis coli down-regulated 1	18	10444624	N48299	147495	18p11.22	Hs.293274	4	membrane integral to membrane
210971_s_at	0.541	3.972	2.910	1.065e-02	0.353	-2.688	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11	13255900	AB000815	406	11p15	Hs.65734	37	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction circadian rhythm aryl hydrocarbon receptor binding positive regulation of transcription from RNA polymerase II promoter Hsp90 protein binding	Circadian rhythm - mammal
202116_at	-0.279	7.182	-2.908	1.070e-02	0.354	-2.692	DPF2	D4, zinc and double PHD fingers family 2	11	64857921	NM_006268	5977	11q13	Hs.13495	11	protein binding intracellular nucleus cytoplasm apoptosis zinc ion binding induction of apoptosis by extracellular signals regulation of transcription metal ion binding
239250_at	0.615	6.194	2.908	1.070e-02	0.354	-2.692	ZNF542	zinc finger protein 542	19	61571279, 61571476	BE966038	147947	19q13.43	Hs.467326	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
205441_at	-0.314	7.035	-2.907	1.071e-02	0.354	-2.693	OCEL1	occludin/ELL domain containing 1	19	17198054	NM_024578	79629	19p13.11	Hs.422676	3
213603_s_at	0.391	5.445	2.907	1.072e-02	0.354	-2.694	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	22	-35951255	BE138888	5880	22q13.1	Hs.517601	58	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction nuclear envelope cytoplasm chemotaxis signal transduction small GTPase mediated signal transduction positive regulation of cell proliferation regulation of hydrogen peroxide metabolic process cell projection assembly actin cytoskeleton organization regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Pancreatic cancer
226008_at	-0.316	7.262	-2.907	1.072e-02	0.354	-2.694	NDNL2	necdin-like 2	15	-27347649	AA627644	56160	15q13.1	Hs.719283	8	protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of growth
224712_x_at	0.312	5.572	2.906	1.073e-02	0.354	-2.695	C19orf42	chromosome 19 open reading frame 42	19	-16617958	AI656658	79086	19p13.11	Hs.356467	1	membrane integral to membrane
205177_at	0.381	12.643	2.905	1.076e-02	0.354	-2.697	TNNI1	troponin I type 1 (skeletal, slow)	1	-199639517	NM_003281	7135	1q31.3	Hs.320890	31	actin binding tropomyosin binding troponin complex regulation of striated muscle contraction
1556730_at	0.244	2.964	2.905	1.076e-02	0.354	-2.697	LOC652993	hypothetical LOC652993	12		AK074510	652993	12q21	Hs.585591	1
216081_at	0.440	4.533	2.905	1.077e-02	0.354	-2.698	LAMA4	laminin, alpha 4	6	-112681678, -112535826	AK027151	3910	6q21	Hs.654572	32	receptor binding extracellular matrix structural constituent extracellular region basal lamina laminin-1 complex regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
225324_at	-0.536	7.581	-2.904	1.077e-02	0.354	-2.698	CRLS1	cardiolipin synthase 1	20	5934738, 5935897	AL035461	54675	20p13-p12.3	Hs.224764	14	mitochondrion mitochondrial inner membrane phospholipid biosynthetic process membrane integral to membrane transferase activity phosphotransferase activity, for other substituted phosphate groups	Glycerophospholipid metabolism Metabolic pathways
208562_s_at	-0.307	4.642	-2.903	1.079e-02	0.354	-2.700	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	12	-21849374, -21841590	NM_020297	10060	12p12.1	Hs.446050	35	nucleotide binding receptor activity transporter activity ATP binding transport sulfonylurea receptor activity ATP-sensitive potassium channel complex potassium ion import potassium channel regulator activity membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances defense response to virus	ABC transporters
228882_at	0.423	5.286	2.903	1.079e-02	0.354	-2.700	TUB	tubby homolog (mouse)	11	8016755, 8059484	AL042088	7275	11p15.5	Hs.231850 Hs.568986	16	nucleus cytoplasm response to stimulus
201454_s_at	-0.451	9.084	-2.903	1.080e-02	0.354	-2.700	NPEPPS	aminopeptidase puromycin sensitive	17	42963442	AW055008	9520	17q21	Hs.443837	14	aminopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
217995_at	-0.410	9.138	-2.903	1.081e-02	0.354	-2.701	SQRDL	sulfide quinone reductase-like (yeast)	15	43714547	NM_021199	58472	15q15	Hs.511251	6	mitochondrion mitochondrial inner membrane oxidoreductase activity oxidation reduction
226926_at	-0.245	5.441	-2.903	1.081e-02	0.354	-2.701	DMKN	dermokine	19	-40686045, -40679961, -40679961, -40679961	AA706316	93099	19q13.12	Hs.417795	7	extracellular region extracellular space
201023_at	-0.430	9.598	-2.903	1.081e-02	0.354	-2.702	TAF7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	5	-140678240	NM_005642	6879	5q31	Hs.438838	38	spermine transport transcription factor activity transcription coactivator activity nucleus transcription factor TFIID complex nucleolus cytoplasm Golgi apparatus transcription initiation from RNA polymerase II promoter negative regulation of protein kinase activity positive transcription elongation factor complex b negative regulation of specific transcription from RNA polymerase II promoter promoter binding general RNA polymerase II transcription factor activity specific transcriptional repressor activity transcription initiation factor activity estrogen receptor signaling pathway transcription factor TFTC complex histone acetyltransferase binding negative regulation of histone acetylation vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding	Basal transcription factors
204142_at	-0.612	6.051	-2.902	1.083e-02	0.354	-2.703	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	NM_017512	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
204198_s_at	0.277	3.687	2.902	1.083e-02	0.354	-2.703	RUNX3	runt-related transcription factor 3	1	-25098588, -25098588	AA541630	864	1p36	Hs.170019	95	transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter induction of apoptosis cell proliferation negative regulation of cell cycle negative regulation of epithelial cell proliferation
201735_s_at	-0.499	6.971	-2.901	1.085e-02	0.354	-2.704	CLCN3	chloride channel 3	4	170778296	NM_001829	1182	4q33	Hs.481186	28	nucleotide binding ion channel activity voltage-gated chloride channel activity protein binding ATP binding early endosome early endosome late endosome late endosome Golgi apparatus Golgi apparatus ion transport chloride transport regulation of pH cell surface vesicle membrane vesicle membrane antiporter activity membrane integral to membrane PDZ domain binding PDZ domain binding chloride ion binding cytoplasmic vesicle protein homodimerization activity protein heterodimerization activity protein heterodimerization activity endosomal lumen acidification
240230_s_at	0.293	5.509	2.901	1.086e-02	0.354	-2.705	LOC642826	hypothetical LOC642826	10	-46662697, 47805861	AW000942	642826	10q11.22	Hs.463017 Hs.647204 Hs.711074 Hs.711898 Hs.718802	2
209406_at	-0.361	8.221	-2.900	1.087e-02	0.354	-2.706	BAG2	BCL2-associated athanogene 2	6	57145062	AF095192	9532	6p12.1-p11.2	Hs.719303	16	protein binding protein folding apoptosis protein metabolic process
207417_s_at	0.430	3.952	2.898	1.092e-02	0.355	-2.710	ZNF177	zinc finger protein 177	19	9334695	NM_003451	7730	19p13.2	Hs.172979	4	negative regulation of transcription from RNA polymerase II promoter DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
206076_at	-0.356	5.596	-2.898	1.092e-02	0.355	-2.711	LRRC23	leucine rich repeat containing 23	12	6884157	NM_006992	10233	12p13	Hs.155586	10	molecular_function protein binding cellular_component biological_process
236565_s_at	1.141	6.053	2.897	1.094e-02	0.356	-2.712	LARP6	La ribonucleoprotein domain family, member 6	15	-68930821, -68910942	BF792126	55323	15q23	Hs.416755	5	RNA binding nucleus cytoplasm RNA processing ribonucleoprotein complex
1562901_at	-0.227	2.854	-2.897	1.094e-02	0.356	-2.712	LOC400456	hypothetical protein LOC400456	15		BC040875	400456	15q26.2	Hs.632160	1
212966_at	0.454	3.806	2.896	1.096e-02	0.356	-2.713	HIC2	hypermethylated in cancer 2	22	20101692	AL043112	23119	22q11.21	Hs.632767	12	DNA binding intracellular nucleus protein C-terminus binding zinc ion binding regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding
218469_at	-0.982	4.026	-2.896	1.096e-02	0.356	-2.714	GREM1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	15	30797496	NM_013372	26585	15q13-q15	Hs.40098	28	cytokine activity protein binding extracellular region extracellular space multicellular organismal development nervous system development
201946_s_at	-0.546	8.231	-2.895	1.098e-02	0.356	-2.715	CCT2	chaperonin containing TCP1, subunit 2 (beta)	12	68265474	AL545982	10576	12q15	Hs.189772	19	nucleotide binding ATP binding nucleus nucleolus cytoplasm cytosol chaperonin-containing T-complex protein folding unfolded protein binding
236172_at	0.260	3.712	2.895	1.098e-02	0.356	-2.715	LTB4R	leukotriene B4 receptor	14	23850544, 23852152	AW206817	1241	14q11.2-q12	Hs.567248	43	nucleotide binding leukotriene B4 receptor activity receptor activity plasma membrane integral to plasma membrane cell motion muscle contraction inflammatory response immune response signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	Neuroactive ligand-receptor interaction
237033_at	-0.294	4.818	-2.894	1.101e-02	0.357	-2.717	FAM159A	family with sequence similarity 159, member A	1	52871653	AI202832	348378	1p32.3	Hs.424589	2	membrane integral to membrane
1552323_s_at	0.584	3.828	2.893	1.102e-02	0.357	-2.719	FAM122C	family with sequence similarity 122C	X	133768889	NM_138819	159091	Xq26.3	Hs.269127	3
243481_at	0.262	4.148	2.891	1.107e-02	0.358	-2.723	RHOJ	ras homolog gene family, member J	14	62740897	AA181207	57381	14q23.2	Hs.656339	8	nucleotide binding GTPase activity protein binding GTP binding cellular_component intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape actin cytoskeleton organization
1569949_at	0.688	8.496	2.890	1.109e-02	0.358	-2.724	GRK5	G protein-coupled receptor kinase 5	10	120957186	BC018116	2869	10q24-qter	Hs.524625	38	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity protein kinase C binding protein binding ATP binding phospholipid binding soluble fraction cytoplasm plasma membrane protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger tachykinin receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway transferase activity	Chemokine signaling pathway Endocytosis
1556176_at	-0.337	5.421	-2.888	1.114e-02	0.359	-2.728	TAF8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa	6	42126228	BU618741	129685	6p21.1	Hs.520122	17	inner cell mass cell proliferation DNA binding protein binding nucleus transcription factor TFIID complex cytoplasm multicellular organismal development transcription activator activity cell differentiation regulation of transcription regulation of fat cell differentiation positive regulation of transcription, DNA-dependent
221538_s_at	0.458	6.832	2.886	1.118e-02	0.360	-2.731	PLXNA1	plexin A1	3	128190191	AL136663	5361	3q21.3	Hs.432329	18	receptor activity protein binding cellular_component intracellular membrane fraction signal transduction multicellular organismal development membrane integral to membrane semaphorin receptor activity	Axon guidance
237447_at	0.363	5.134	2.885	1.120e-02	0.361	-2.733	C22orf45	chromosome 22 open reading frame 45	22		BF509218	646023	22q11.23	Hs.712771	2
208002_s_at	0.307	4.767	2.885	1.120e-02	0.361	-2.733	ACOT7	acyl-CoA thioesterase 7	1	-6246918, -6246918, -6246918, -6246918	NM_007274	11332	1p36.31-p36.11	Hs.126137	11	acyl-CoA binding carboxylesterase activity cytoplasm mitochondrion lipid metabolic process palmitoyl-CoA hydrolase activity hydrolase activity	Biosynthesis of unsaturated fatty acids
1553990_at	0.471	6.260	2.884	1.123e-02	0.361	-2.735	C16orf79	chromosome 16 open reading frame 79	16	-2199254	BC039154	283870	16p13.3	Hs.647399	1	membrane integral to membrane
202374_s_at	-0.246	6.766	-2.883	1.126e-02	0.361	-2.737	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	NM_012414	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
213845_at	-0.581	4.027	-2.883	1.126e-02	0.361	-2.737	GRIK2	glutamate receptor, ionotropic, kainate 2	6	101953625	AL355532	2898	6q16.3-q21	Hs.98262	53	receptor activity ion channel activity extracellular-glutamate-gated ion channel activity plasma membrane integral to plasma membrane ion transport glutamate signaling pathway kainate selective glutamate receptor activity cell junction induction of programmed cell death in response to chemical stimulus synapse postsynaptic membrane regulation of short-term neuronal synaptic plasticity positive regulation of synaptic transmission neuron apoptosis	Neuroactive ligand-receptor interaction
1558113_at	0.356	4.200	2.883	1.126e-02	0.361	-2.737	FAM78B	family with sequence similarity 78, member B	1	-164305879	BM545032	149297	1q24.1	Hs.493518	5
213521_at	0.306	6.700	2.882	1.127e-02	0.361	-2.738	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	2	130830049	AW575379	26469	2q21.1	Hs.516390 Hs.591549	16	non-membrane spanning protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity
204194_at	-0.599	5.949	-2.881	1.130e-02	0.362	-2.741	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	21	29593090, 29593607, 29599430	NM_001186	571	21q22.11	Hs.154276	30	transcription factor activity nucleus nucleolus cytosol regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
231820_x_at	0.331	4.918	2.880	1.131e-02	0.362	-2.742	ZNF587	zinc finger protein 587	19	63053080	BF038484	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212094_at	0.915	4.959	2.879	1.134e-02	0.362	-2.744	PEG10	paternally expressed 10	7	94123572	AL582836	23089	7q21	Hs.147492	25	DNA binding aspartic-type endopeptidase activity nucleus cytoplasm proteolysis apoptosis zinc ion binding cell differentiation metal ion binding
224443_at	0.722	6.229	2.879	1.134e-02	0.362	-2.744	C1orf97	chromosome 1 open reading frame 97	1	209622719	BC005997	84791	1q32.3	Hs.523932	4
218424_s_at	-0.281	7.754	-2.878	1.138e-02	0.363	-2.747	STEAP3	STEAP family member 3	2	119697853	NM_018234	55240	2q14.2	Hs.647822	11	binding iron ion binding copper ion binding endosome ion transport iron ion transport apoptosis cell cycle electron carrier activity membrane integral to membrane oxidoreductase activity metal ion binding FAD binding oxidation reduction	p53 signaling pathway
217627_at	0.577	5.847	2.877	1.139e-02	0.363	-2.748	ZNF573	zinc finger protein 573	19	-42921040	BE515346	126231	19q13.12	Hs.531262	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201856_s_at	-0.486	5.459	-2.876	1.141e-02	0.363	-2.749	ZFR	zinc finger RNA binding protein	5	-32390212	BC000376	51663	5p13.3	Hs.435231	6	DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding
225208_s_at	-0.275	7.809	-2.876	1.141e-02	0.363	-2.749	FAM103A1	family with sequence similarity 103, member A1	15	81445998	AW575350	83640	15q25.2	Hs.80624	3
227718_at	-0.571	6.497	-2.875	1.143e-02	0.363	-2.751	PURB	purine-rich element binding protein B	7	-44882416	BF337790	5814	7p13	Hs.349150 Hs.596321	13	translation repressor activity, nucleic acid binding double-stranded DNA binding single-stranded DNA binding transcription factor activity mRNA binding nucleus DNA replication factor A complex transcription factor binding specific transcriptional repressor activity purine-rich negative regulatory element binding regulation of transcription regulation of myeloid cell differentiation negative regulation of transcription, DNA-dependent SMAD binding
205909_at	0.371	4.225	2.874	1.145e-02	0.364	-2.753	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)	14	-49180028	NM_002692	5427	14q21-q22	Hs.162777	14	DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm DNA-dependent DNA replication DNA repair nucleotide-excision repair, DNA gap filling transferase activity nucleotidyltransferase activity	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
203674_at	0.293	6.874	2.874	1.146e-02	0.364	-2.753	HELZ	helicase with zinc finger	17	-62497015	NM_014877	9931	17q24.2	Hs.370140 Hs.569824 Hs.596366	8	nucleotide binding nucleic acid binding helicase activity ATP binding nucleus zinc ion binding hydrolase activity metal ion binding
201543_s_at	0.300	7.255	2.873	1.148e-02	0.364	-2.755	SAR1A	SAR1 homolog A (S. cerevisiae)	10	-71579973	NM_020150	56681	10q22.1	Hs.499960 Hs.594910	13	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport vesicle-mediated transport sarcoplasmic reticulum
1569354_at	0.253	3.689	2.873	1.149e-02	0.364	-2.755	NSUN6	NOL1/NOP2/Sun domain family, member 6	10	-18874269	BC033534	221078	10p12.31	Hs.396175	4	RNA binding methyltransferase activity transferase activity
221805_at	0.202	2.231	2.872	1.150e-02	0.364	-2.757	NEFL	neurofilament, light polypeptide	8	-24864387	AL537457	4747	8p21	Hs.521461	57	structural constituent of cytoskeleton neurofilament protein C-terminus binding anterograde axon cargo transport retrograde axon cargo transport axon transport of mitochondrion axon TSC1-TSC2 complex neurofilament bundle assembly neurofilament bundle assembly identical protein binding intermediate filament organization	Amyotrophic lateral sclerosis (ALS)
222622_at	0.500	9.451	2.872	1.151e-02	0.364	-2.757	PGP	phosphoglycolate phosphatase	16	-2201603	BG284709	283871	16p13.3	Hs.442634	9	skeletal system development membrane fraction carbohydrate metabolic process metabolic process phosphoglycolate phosphatase activity morphogenesis of embryonic epithelium hydrolase activity regulation of cell adhesion odontogenesis of dentine-containing tooth regulation of apoptosis	Glyoxylate and dicarboxylate metabolism Metabolic pathways
221743_at	-0.260	10.502	-2.871	1.154e-02	0.365	-2.759	CUGBP1	CUG triplet repeat, RNA binding protein 1	11	-47446520, -47446520, -47446520	AI472139	10658	11p11	Hs.632137	34	nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding
1563607_x_at	-0.220	4.532	-2.870	1.155e-02	0.365	-2.760	hCG_2045089	hypothetical LOC286359	9	-99192941	AL833510	286359	9q22.33	Hs.132262	2
207033_at	0.309	4.212	2.869	1.158e-02	0.365	-2.762	GIF	gastric intrinsic factor (vitamin B synthesis)	11	-59353321	NM_005142	2694	11q13	Hs.110014	13	extracellular region ion transport cobalt ion transport cobalt ion transmembrane transporter activity cobalamin transport cobalamin binding cobalt ion binding
235457_at	0.519	5.597	2.868	1.159e-02	0.365	-2.764	MAML2	mastermind-like 2 (Drosophila)	11	-95351087	AI769569	84441	11q21	Hs.428214	17	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
214180_at	0.295	5.544	2.868	1.160e-02	0.365	-2.764	MAN1C1	mannosidase, alpha, class 1C, member 1	1	25816545	AW340588	57134	1p35	Hs.197043	26	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding Golgi apparatus protein amino acid N-linked glycosylation metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds integral to Golgi membrane	N-Glycan biosynthesis Metabolic pathways
200768_s_at	-0.310	8.543	-2.867	1.162e-02	0.365	-2.765	MAT2A	methionine adenosyltransferase II, alpha	2	85619798	BC001686	4144	2p11.2	Hs.516157	18	nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
37232_at	-0.195	5.388	-2.867	1.163e-02	0.365	-2.766	KIAA0586	KIAA0586	14	57964462	AB011158	9786	14q23.1	Hs.232532	8
209032_s_at	0.477	6.063	2.867	1.164e-02	0.365	-2.767	CADM1	cell adhesion molecule 1	11	-114549554	AF132811	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
241834_at	0.666	6.002	2.866	1.164e-02	0.365	-2.767	IPW	imprinted in Prader-Willi syndrome (non-protein coding)	15	22912784	AW299520	3653	15q11-q12	Hs.555970	3
205007_s_at	0.548	6.177	2.865	1.167e-02	0.365	-2.769	CIB2	calcium and integrin binding family member 2	15	-76184045	AI478592	10518	15q24	Hs.129867	6	calcium ion binding protein binding
200867_at	-0.483	7.326	-2.865	1.168e-02	0.365	-2.770	RNF114	ring finger protein 114	20	47986320	AL031685	55905	20q13.13	Hs.144949	9	protein binding intracellular multicellular organismal development spermatogenesis zinc ion binding cell differentiation metal ion binding
235292_at	0.367	2.774	2.865	1.168e-02	0.365	-2.770	FLJ32255	hypothetical protein LOC643977	5		BE875232	643977	5p12	Hs.535791	1
202583_s_at	-0.542	6.875	-2.865	1.168e-02	0.365	-2.770	RANBP9	RAN binding protein 9	6	-13729708	NM_005493	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
212501_at	-0.641	10.232	-2.864	1.169e-02	0.365	-2.771	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	20	48240782	AL564683	1051	20q13.1	Hs.517106 Hs.701858 Hs.719041	186	embryonic placenta development RNA polymerase II transcription factor activity, enhancer binding nucleus cytoplasm regulation of transcription, DNA-dependent anti-apoptosis induction of apoptosis acute-phase response inflammatory response immune response transcription activator activity neuron differentiation protein homodimerization activity sequence-specific DNA binding regulation of interleukin-6 biosynthetic process fat cell differentiation positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity
212103_at	-0.354	7.476	-2.864	1.171e-02	0.365	-2.772	KPNA6	karyopherin alpha 6 (importin alpha 7)	1	32346230	BG403834	23633	1p35.1-p34.3	Hs.470588 Hs.711019	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
239043_at	0.584	3.229	2.863	1.171e-02	0.365	-2.773	ZNF404	zinc finger protein 404	19	-49068354	AA084273	342908	19q13.31	Hs.76561	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
206204_at	1.017	5.316	2.863	1.171e-02	0.365	-2.773	GRB14	growth factor receptor-bound protein 14	2	-165057568	NM_004490	2888	2q22-q24	Hs.411881	19	SH3/SH2 adaptor activity protein binding cytoplasm endosome microsome Golgi apparatus plasma membrane signal transduction
236573_at	0.689	10.726	2.863	1.172e-02	0.365	-2.773	MIB1	mindbomb homolog 1 (Drosophila)	18	17575542	AI819052	57534	18q11.2	Hs.140903 Hs.658808	15	blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding
239527_at	0.274	2.997	2.863	1.173e-02	0.365	-2.774	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	BF103605	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
225105_at	1.945	8.723	2.862	1.174e-02	0.365	-2.774	C12orf75	chromosome 12 open reading frame 75	12	104248543	BF969397	387882	12q23.3	Hs.368938	3
216294_s_at	-0.359	4.775	-2.862	1.174e-02	0.365	-2.775	KIAA1109	KIAA1109	4	123311207	AL137254	84162	4q27	Hs.408142	12	membrane integral to membrane
205206_at	-0.810	7.950	-2.862	1.174e-02	0.365	-2.775	KAL1	Kallmann syndrome 1 sequence	X	-8456914	NM_000216	3730	Xp22.32	Hs.521869	35	serine-type endopeptidase inhibitor activity extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix extracellular space chemotaxis cell adhesion axon guidance cell surface peptidase inhibitor activity
239074_at	0.274	5.489	2.862	1.175e-02	0.365	-2.775	LOC400581	GRB2-related adaptor protein-like	17	18971506	AI538454	400581	17p11.2	Hs.661470 Hs.677674	1	protein binding
211801_x_at	-0.481	4.834	-2.861	1.176e-02	0.365	-2.776	MFN1	mitofusin 1	3	180548173	AF329637	55669	3q26.33	Hs.478383	16	nucleotide binding GTPase activity GTP binding cytoplasm mitochondrion mitochondrial outer membrane mitochondrial fusion biological_process membrane integral to membrane hydrolase activity
238070_at	-0.423	5.013	-2.861	1.177e-02	0.365	-2.777	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	AA573217	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
214574_x_at	0.290	5.450	2.861	1.177e-02	0.365	-2.777	LST1	leukocyte specific transcript 1	6	31661949, 31662603, 3000093, 3000747, 2801557, 2802211	NM_007161	7940	6p21.3	Hs.436066	20	cell morphogenesis molecular_function protein binding cytoplasm Golgi apparatus immune response regulation of cell shape anatomical structure morphogenesis membrane integral to membrane dendrite development negative regulation of lymphocyte proliferation
242584_at	0.624	5.343	2.861	1.178e-02	0.365	-2.778	FAM161A	family with sequence similarity 161, member A	2	-61905486	AI954412	84140	2p15	Hs.440466	7
233314_at	0.294	3.793	2.860	1.179e-02	0.365	-2.778	PTEN	phosphatase and tensin homolog	10	89613174	AK021487	5728	10q23.3	Hs.500466	557	regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade	Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer
204305_at	-0.418	6.030	-2.860	1.179e-02	0.365	-2.778	MIPEP	mitochondrial intermediate peptidase	13	-23202327	NM_005932	4285	13q12	Hs.507498	6	magnesium ion binding metalloendopeptidase activity iron ion binding calcium ion binding mitochondrion mitochondrial matrix proteolysis mitochondrial protein processing during import peptidase activity zinc ion binding manganese ion binding cobalt ion binding
229139_at	-0.663	10.879	-2.860	1.180e-02	0.365	-2.779	JPH1	junctophilin 1	8	-75309492	AI202201	56704	8q21	Hs.657367	9	molecular_function microsome plasma membrane muscle organ development structural constituent of muscle junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc junctional membrane complex regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
221822_at	-0.454	6.879	-2.860	1.180e-02	0.365	-2.779	CCDC101	coiled-coil domain containing 101	16	28472749	BE544663	112869	16p11.2	Hs.655476	6	nucleus regulation of transcription
210136_at	-0.607	7.580	-2.859	1.181e-02	0.365	-2.780	MBP	myelin basic protein	18	-72853726, -72819776, -72819776	AW070431	4155	18q23	Hs.551713	102	plasma membrane immune response synaptic transmission central nervous system development structural constituent of myelin sheath internode region of axon myelination cell projection cell soma myelin sheath
227179_at	-0.328	8.385	-2.858	1.184e-02	0.365	-2.782	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)	8	-74624394	AK002152	27067	8q13-q21.1	Hs.561815	11	double-stranded RNA binding intracellular nucleus nucleolus cytoplasm endoplasmic reticulum microtubule transport
203197_s_at	0.365	8.562	2.858	1.184e-02	0.365	-2.782	C1orf123	chromosome 1 open reading frame 123	1	-53452359	AW157077	54987	1p32.3	Hs.525391	4	molecular_function cellular_component biological_process
215379_x_at	0.592	6.110	2.858	1.185e-02	0.365	-2.783	IGL@	immunoglobulin lambda locus	22		AV698647	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
235698_at	0.379	5.197	2.858	1.185e-02	0.365	-2.783	ZFP90	zinc finger protein 90 homolog (mouse)	16	67131161	AA771779	146198	16q22.1	Hs.461074 Hs.709017	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226494_at	-0.210	5.595	-2.856	1.190e-02	0.366	-2.787	KIAA1543	KIAA1543	19	7566787	AB040976	57662	19p13.2	Hs.17686	9	molecular_function protein binding cellular_component biological_process
229367_s_at	0.474	6.723	2.854	1.193e-02	0.367	-2.789	GIMAP6	GTPase, IMAP family member 6	7	-149953398	AW130536	474344		Hs.647105	7	nucleotide binding GTP binding
205694_at	-1.364	6.660	-2.853	1.196e-02	0.368	-2.791	TYRP1	tyrosinase-related protein 1	9	12683385	NM_000550	7306	9p23	Hs.270279	49	copper ion binding protein binding membrane integral to membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen melanocyte differentiation melanosome organization melanosome membrane melanin biosynthetic process protein homodimerization activity acetoacetic acid metabolic process pigmentation metal ion binding protein heterodimerization activity oxidation reduction	Tyrosine metabolism Metabolic pathways Melanogenesis
220004_at	-0.255	2.801	-2.853	1.197e-02	0.368	-2.792	DDX43	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43	6	74161005	NM_018665	55510	6q12-q13	Hs.125507	12	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding intracellular hydrolase activity
225225_at	-0.266	10.855	-2.851	1.202e-02	0.368	-2.796	LOC729082	hypothetical protein LOC729082	15	39363492	BF791544	729082	15q15.1	Hs.380164	2
232204_at	0.429	4.408	2.851	1.202e-02	0.368	-2.796	EBF1	early B-cell factor 1	5	-158055500	AF208502	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
221898_at	-0.437	6.126	-2.850	1.202e-02	0.368	-2.796	PDPN	podoplanin	1	13782838, 13784553	AU154455	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
221687_s_at	-0.234	5.994	-2.850	1.203e-02	0.368	-2.796	FAM125B	family with sequence similarity 125, member B	9	128128948, 128128948	BC000122	89853	9q33.3	Hs.162659	4	endosome protein transport membrane	Endocytosis
213198_at	-0.250	8.138	-2.850	1.204e-02	0.368	-2.797	ACVR1B	activin A receptor, type IB	12	50631752, 50631752, 50631752	AL117643	91	12q13	Hs.438918	39	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding in utero embryonic development hair follicle development protein serine/threonine kinase activity receptor activity ATP binding integral to plasma membrane induction of apoptosis signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway embryonic development cell surface membrane activin receptor activity, type I transferase activity peptidyl-threonine phosphorylation growth factor binding manganese ion binding negative regulation of cell growth ubiquitin protein ligase binding positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of erythrocyte differentiation SMAD binding protein amino acid autophosphorylation activin binding	MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia
230677_at	-0.213	5.487	-2.848	1.208e-02	0.369	-2.800	C14orf73	chromosome 14 open reading frame 73	14	102636233	AW006941	91828	14q32.32	Hs.37712	2
242274_x_at	0.407	4.133	2.848	1.208e-02	0.369	-2.800	SLC25A42	solute carrier family 25, member 42	19	19035807	AI057363	284439	19p13.11	Hs.303669	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
227084_at	-1.014	8.938	-2.848	1.208e-02	0.369	-2.800	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	AW339310	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
228555_at	-0.356	6.532	-2.848	1.209e-02	0.369	-2.801	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	4	-114597792, -114591638	AA029441	817	4q26	Hs.144114	29	G1/S transition of mitotic cell cycle nucleotide binding regulation of cell growth calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm calcium- and calmodulin-dependent protein kinase complex calcium ion transport transferase activity T-tubule protein amino acid autophosphorylation cardiac muscle contraction	ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma
226196_s_at	0.243	6.218	2.848	1.209e-02	0.369	-2.801	C14orf179	chromosome 14 open reading frame 179	14	75521848	AW827281	112752	14q24.3	Hs.532626	5
1559206_at	-0.220	2.325	-2.847	1.210e-02	0.369	-2.802	PSEN1	presenilin 1	14	72672895	BC002708	5663	14q24.3	Hs.3260	386	kinetochore endopeptidase activity membrane fraction integral to nuclear inner membrane nuclear outer membrane mitochondrion endoplasmic reticulum Golgi apparatus integral to plasma membrane membrane protein ectodomain proteolysis apoptosis anti-apoptosis chromosome segregation Notch receptor processing intracellular signaling cascade beta-catenin binding cell death peptidase activity cell surface membrane cell-cell adhesion protein processing PDZ domain binding endoplasmic reticulum calcium ion homeostasis regulation of phosphorylation amyloid precursor protein catabolic process positive regulation of catalytic activity	Wnt signaling pathway Notch signaling pathway Neurotrophin signaling pathway Alzheimer's disease
225539_at	-0.504	5.600	-2.847	1.210e-02	0.369	-2.802	ZNF295	zinc finger protein 295	21	-42280008	AP001745	49854	21q22.3	Hs.434947 Hs.618406	10	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
201227_s_at	0.293	10.740	2.847	1.212e-02	0.369	-2.803	NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	10	-102273486	NM_005004	4714	10q23.2-q23.33	Hs.523215	16	NADH dehydrogenase activity mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I endoplasmic reticulum mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1558924_s_at	-0.821	6.486	-2.846	1.213e-02	0.369	-2.804	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	BF673049	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
204773_at	0.214	7.128	2.845	1.216e-02	0.370	-2.806	IL11RA	interleukin 11 receptor, alpha	9	34642181, 34643931, 34643931	NM_004512	3590	9p13	Hs.591088	26	cytokine receptor activity integral to plasma membrane membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
226131_s_at	-0.298	13.104	-2.844	1.218e-02	0.370	-2.807	RPS16	ribosomal protein S16	19	-44615686	AA583817	6217	19q13.1	Hs.397609	24	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
226589_at	0.300	5.513	2.844	1.219e-02	0.370	-2.808	TMEM192	transmembrane protein 192	4	-166216679	BE964222	201931	4q32.3	Hs.708090	3	membrane integral to membrane
228947_x_at	-0.248	5.809	-2.843	1.221e-02	0.370	-2.810	TMEM204	transmembrane protein 204	16	1524231	AW612362	79652	16p13.3	Hs.459652	7	plasma membrane adherens junction response to stress integral to membrane cell junction
235878_at	0.297	3.801	2.843	1.222e-02	0.370	-2.810	TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	2	9901021	AA780048	9014	2p25	Hs.584833	15	transcription factor activity nucleus nucleoplasm transcription, DNA-dependent regulation of transcription
243179_at	0.609	4.889	2.841	1.227e-02	0.371	-2.814	LOC100130360	hypothetical LOC100130360	6		BG231554	100130360	6p22.3
236064_at	0.302	4.403	2.840	1.227e-02	0.371	-2.814	SLC25A35	solute carrier family 25, member 35	17	-8131806	AW966184	399512	17p13.1	Hs.118918	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
207901_at	-0.273	2.040	-2.840	1.228e-02	0.371	-2.815	IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	5	-158674368	NM_002187	3593	5q31.1-q33.1	Hs.674	222	natural killer cell activation during immune response positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target signal transducer activity cytokine receptor activity cytokine activity interleukin-12 receptor binding protein binding extracellular region cell cycle arrest cell surface receptor linked signal transduction response to UV-B membrane cell migration sensory perception of pain positive regulation of interferon-gamma production positive regulation of natural killer cell activation positive regulation of smooth muscle cell apoptosis regulation of cytokine biosynthetic process T-helper 1 type immune response T-helper cell differentiation positive regulation of activated T cell proliferation interleukin-12 alpha subunit binding protein homodimerization activity interleukin-12 complex positive regulation of interferon-gamma biosynthetic process positive regulation of cell adhesion protein heterodimerization activity negative regulation of smooth muscle cell proliferation	Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Jak-STAT signaling pathway Type I diabetes mellitus Allograft rejection
219284_at	-0.512	7.040	-2.840	1.228e-02	0.371	-2.815	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1	3	-123941535	NM_024610	79663	3q21.1	Hs.29169	5	cytoplasm
208029_s_at	-0.715	8.976	-2.840	1.229e-02	0.371	-2.815	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	NM_018407	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
1565269_s_at	-0.568	5.359	-2.839	1.230e-02	0.371	-2.816	ATF1	activating transcription factor 1	12	49444085	AF047022	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
228071_at	0.653	6.480	2.839	1.231e-02	0.371	-2.817	GIMAP7	GTPase, IMAP family member 7	7	149842877	AA858297	168537	7q36.1	Hs.647074	6	nucleotide binding GTP binding
1569722_s_at	0.203	3.782	2.838	1.232e-02	0.371	-2.818	LOC219731	hypothetical protein LOC219731	10		BC032757	219731	10p14	Hs.585473	1
206408_at	0.275	3.452	2.838	1.234e-02	0.371	-2.819	LRRTM2	leucine rich repeat transmembrane neuronal 2	5	-138232977	NM_015564	26045	5q31.2	Hs.656653	6	protein binding membrane integral to membrane
218894_s_at	0.262	4.628	2.838	1.234e-02	0.371	-2.819	MAGOHB	mago-nashi homolog B (Drosophila)	12	-10648060	NM_018048	55110	12p13.2	Hs.104650	6	RNA binding nucleus mRNA processing transport RNA splicing mRNA transport
209031_at	0.696	6.696	2.837	1.235e-02	0.371	-2.820	CADM1	cell adhesion molecule 1	11	-114549554	AL519710	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
225130_at	-0.264	5.923	-2.837	1.237e-02	0.371	-2.821	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	AW003734	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
236937_at	-0.436	5.404	-2.836	1.237e-02	0.371	-2.821	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)	3	186012624	BF108423	23355	3q27.2	Hs.269263	6	protein binding zinc ion binding metal ion binding
205413_at	-1.467	6.229	-2.836	1.239e-02	0.371	-2.822	MPPED2	metallophosphoesterase domain containing 2	11	-30388194, -30362615	NM_001584	744	11p13	Hs.289795	8	nervous system development hydrolase activity
224607_s_at	-0.267	8.276	-2.836	1.239e-02	0.371	-2.823	SRP68	signal recognition particle 68kDa	17	-71546785	BG398597	6730	17q25.1	Hs.514495	11	RNA binding signal recognition particle binding nucleus nucleolus cytoplasm endoplasmic reticulum signal recognition particle, endoplasmic reticulum targeting ribosome response to drug	Protein export
32723_at	0.451	6.344	2.835	1.241e-02	0.371	-2.824	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	20	54400833, 54400980, 54401113	L02547	1477	20q13.2	Hs.172865	19	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA polyadenylation mRNA cleavage
206116_s_at	-0.642	13.052	-2.835	1.242e-02	0.371	-2.824	TPM1	tropomyosin 1 (alpha)	15	61121890, 61121890, 61127688	NM_000366	7168	15q22.1	Hs.133892	76	stress fiber positive regulation of heart rate by epinephrine actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction cytoskeleton organization regulation of heart contraction structural constituent of muscle sarcomere muscle filament sliding negative regulation of cell migration ruffle organization bleb ruffle membrane positive regulation of ATPase activity cellular response to reactive oxygen species wound healing sarcomere organization positive regulation of cell adhesion positive regulation of stress fiber formation ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
33850_at	-0.307	8.659	-2.834	1.243e-02	0.371	-2.825	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	W28892	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
210960_at	-0.317	3.590	-2.834	1.244e-02	0.371	-2.827	ADRA1D	adrenergic, alpha-1D-, receptor	20	-4149277	M76446	146	20p13	Hs.557	30	negative regulation of the force of heart contraction during baroreceptor response to increased systemic arterial blood pressure norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure receptor activity G-protein coupled receptor activity adrenoceptor activity alpha1-adrenergic receptor activity plasma membrane integral to plasma membrane DNA metabolic process signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger cell-cell signaling multicellular organismal development positive regulation of cell proliferation	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
205161_s_at	0.487	5.494	2.833	1.246e-02	0.371	-2.827	PEX11A	peroxisomal biogenesis factor 11 alpha	15	-88027290	NM_003847	8800	15q26.1	Hs.31034	9	peroxisome peroxisomal membrane integral to peroxisomal membrane signal transduction membrane integral to membrane peroxisome fission
226211_at	-0.729	4.900	-2.833	1.246e-02	0.371	-2.828	MEG3	maternally expressed 3 (non-protein coding)	14	100362197, 100362215	AI291123	55384	14q32	Hs.525589 Hs.593706 Hs.654863 Hs.655127	11
244712_at	-0.318	5.272	-2.833	1.246e-02	0.371	-2.828	MEX3D	mex-3 homolog D (C. elegans)	19	-1505667	AI650529	399664	19p13.3	Hs.436495	4	RNA binding protein binding nucleus cytoplasm zinc ion binding metal ion binding
203564_at	0.242	5.434	2.833	1.246e-02	0.371	-2.828	FANCG	Fanconi anemia, complementation group G	9	-35063834	NM_004629	2189	9p13	Hs.591084	57	cell cycle checkpoint ovarian follicle development damaged DNA binding protein binding nucleus cytoplasm mitochondrion DNA repair response to DNA damage stimulus mitochondrion organization spermatid development response to radiation
207196_s_at	-0.298	8.706	-2.833	1.247e-02	0.371	-2.828	TNIP1	TNFAIP3 interacting protein 1	5	-150389698	NM_006058	10318	5q32-q33.1	Hs.355141	31	protein binding intracellular nucleus cytoplasm translation defense response glycoprotein biosynthetic process pathogenesis negative regulation of viral genome replication
226524_at	-0.299	5.521	-2.833	1.247e-02	0.371	-2.828	C3orf38	chromosome 3 open reading frame 38	3	88281582	AI458735	285237	3p11.1	Hs.476944 Hs.518099	2	apoptosis
218788_s_at	0.398	6.379	2.832	1.248e-02	0.371	-2.829	SMYD3	SET and MYND domain containing 3	1	-243979266	NM_022743	64754	1q44	Hs.567571	18	protein binding nucleus cytoplasm methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
211204_at	0.234	4.669	2.832	1.249e-02	0.371	-2.830	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	6	-83976828	L34035	4199	6q12	Hs.21160	24	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway
207269_at	0.242	4.665	2.832	1.249e-02	0.371	-2.830	DEFA4	defensin, alpha 4, corticostatin	8	-6780754	NM_001925	1669	8p23	Hs.591391	11	extracellular region extracellular space xenobiotic metabolic process defense response to bacterium defense response to fungus
204723_at	0.804	5.615	2.832	1.249e-02	0.371	-2.830	SCN3B	sodium channel, voltage-gated, type III, beta	11	-123005104	AB032984	55800	11q23.3	Hs.4865	19	voltage-gated ion channel activity voltage-gated sodium channel activity plasma membrane ion transport sodium ion transport integral to membrane sodium ion binding
1570279_at	-0.255	3.296	-2.831	1.251e-02	0.371	-2.831	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	9	-106583104	BC034824	19	9q31.1	Hs.719214	321	nucleotide binding ATP binding phospholipid binding phospholipid transporter activity membrane fraction integral to plasma membrane lipid metabolic process transport lysosome organization G-protein coupled receptor protein signaling pathway steroid metabolic process cholesterol metabolic process anion transmembrane transporter activity negative regulation of foam cell differentiation negative regulation of cholesterol storage cholesterol binding membrane endosome transport ATPase activity cholesterol transporter activity syntaxin-13 binding positive regulation of cAMP biosynthetic process small GTPase binding intracellular cholesterol transport Cdc42 protein signal transduction cholesterol efflux cholesterol efflux phospholipid efflux phospholipid efflux apolipoprotein A-I receptor activity high-density lipoprotein particle assembly cholesterol homeostasis reverse cholesterol transport membrane raft phagocytic vesicle interleukin-1 beta secretion phospholipid homeostasis platelet dense granule organization	ABC transporters
232173_at	0.319	5.724	2.830	1.254e-02	0.372	-2.833	CLEC2L	C-type lectin domain family 2, member L	7	138859213	W60866	154790	7q34	Hs.57806	3	binding sugar binding membrane integral to membrane
202257_s_at	0.285	7.130	2.830	1.255e-02	0.372	-2.834	CD2BP2	CD2 (cytoplasmic tail) binding protein 2	16	-30269588, -30269588	NM_006110	10421	16p11.2	Hs.202677	21	nuclear mRNA splicing, via spliceosome protein binding cytoplasm
225730_s_at	0.371	7.536	2.829	1.255e-02	0.372	-2.834	THUMPD3	THUMP domain containing 3	3	9379716	AI921788	25917	3p25.3	Hs.443081	5	RNA binding protein binding methyltransferase activity transferase activity
1554464_a_at	-0.647	5.317	-2.829	1.256e-02	0.372	-2.834	CRTAP	cartilage associated protein	3	33130453	BC008745	10491	3p22.3	Hs.719160	10	extracellular region proteinaceous extracellular matrix
219419_at	-0.351	6.838	-2.828	1.258e-02	0.372	-2.836	C18orf22	chromosome 18 open reading frame 22	18	75895345	NM_024805	79863	18q23	Hs.593610	3	mitochondrion rRNA processing
228372_at	0.317	6.539	2.828	1.259e-02	0.372	-2.837	C10orf128	chromosome 10 open reading frame 128	10	-50033896	AW204712	170371	10q11.23	Hs.385493	1	membrane integral to membrane
222471_s_at	-0.427	9.130	-2.827	1.260e-02	0.372	-2.837	KCMF1	potassium channel modulatory factor 1	2	85051741	AI743396	56888	2p11.2	Hs.654968	7	intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
205693_at	-0.914	11.618	-2.827	1.260e-02	0.372	-2.838	TNNT3	troponin T type 3 (skeletal, fast)	11	1897374	NM_006757	7140	11p15.5	Hs.73454	21	skeletal muscle contraction actin binding tropomyosin binding tropomyosin binding troponin complex regulation of striated muscle contraction troponin C binding calcium-dependent ATPase activity troponin I binding regulation of ATPase activity calcium-dependent protein binding
213004_at	-0.455	6.725	-2.827	1.262e-02	0.372	-2.839	ANGPTL2	angiopoietin-like 2	9	-128889448	AI074333	23452	9q34	Hs.653262	11	receptor binding extracellular region extracellular space signal transduction multicellular organismal development
212093_s_at	-0.565	7.051	-2.826	1.264e-02	0.372	-2.841	MTUS1	mitochondrial tumor suppressor 1	8	-17545583, -17545583, -17545583	AI695017	57509	8p22	Hs.7946	11	nucleus mitochondrion Golgi apparatus plasma membrane
218013_x_at	-0.541	6.579	-2.826	1.264e-02	0.372	-2.841	DCTN4	dynactin 4 (p62)	5	-150068502, -150068502	NM_016221	51164	5q31-q32	Hs.675564	7	nucleus cytoplasm centrosome cytoskeleton protein N-terminus binding	Huntington's disease
227962_at	-0.345	7.234	-2.825	1.265e-02	0.372	-2.841	ACOX1	acyl-Coenzyme A oxidase 1, palmitoyl	17	-71449186	BF435852	51	17q24-q25 17q25.1	Hs.464137	26	acyl-CoA dehydrogenase activity acyl-CoA oxidase activity acyl-CoA oxidase activity cytoplasm mitochondrion peroxisome peroxisomal membrane generation of precursor metabolites and energy lipid metabolic process fatty acid beta-oxidation prostaglandin metabolic process spermatogenesis electron carrier activity protein N-terminus binding FAD binding oxidation reduction	Fatty acid metabolism alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
205037_at	0.296	6.350	2.825	1.266e-02	0.372	-2.842	RABL4	RAB, member of RAS oncogene family-like 4	22	-35484200	NM_006860	11020	22q13.1	Hs.415172	6	nucleotide binding GTP binding small GTPase mediated signal transduction
1555847_a_at	-0.357	7.568	-2.825	1.266e-02	0.372	-2.842	LOC284454	hypothetical protein LOC284454	19		BU617052	284454	19p13.13	Hs.436426
214617_at	0.302	6.133	2.824	1.268e-02	0.373	-2.843	PRF1	perforin 1 (pore forming protein)	10	-72027109	AI445650	5551	10q22	Hs.2200	88	calcium ion binding apoptosis cellular defense response circadian rhythm pathogenesis membrane integral to membrane cytoplasmic membrane-bounded vesicle cytolysis response to ethanol	Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
219371_s_at	-0.636	7.552	-2.824	1.269e-02	0.373	-2.844	KLF2	Kruppel-like factor 2 (lung)	19	16296650	NM_016270	10365	19p13.13-p13.11	Hs.715677	38	transcription factor activity protein binding intracellular nucleus zinc ion binding transcription activator activity positive regulation of transcription metal ion binding
228420_at	-0.201	5.780	-2.822	1.274e-02	0.374	-2.848	PDCD2	programmed cell death 2	6	-170732759, -170728374	AW590850	5134	6q27	Hs.367900	14	DNA binding protein binding nucleus cytoplasm apoptosis zinc ion binding metal ion binding
226533_at	-0.474	6.519	-2.818	1.284e-02	0.376	-2.855	HINT3	histidine triad nucleotide binding protein 3	6	126319553	BF694956	135114	6q22.32	Hs.72325	6	nucleus cytoplasm hydrolase activity
217485_x_at	0.259	6.719	2.818	1.285e-02	0.376	-2.855	PMS2L1	postmeiotic segregation increased 2-like 1 pseudogene	7	-99756198	D38435	5379	7q22.1	Hs.634244 Hs.661055 Hs.709266	7	molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding
238478_at	0.459	5.713	2.818	1.285e-02	0.376	-2.855	BNC2	basonuclin 2	9	-16399500	H97386	54796	9p22.3-p22.2	Hs.656581 Hs.693437	10	intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding
205061_s_at	0.311	7.259	2.818	1.285e-02	0.376	-2.855	EXOSC9	exosome component 9	4	122941921	NM_005033	5393	4q27	Hs.91728	17	3'-5'-exoribonuclease activity nuclear exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing immune response hydrolase activity	RNA degradation
200836_s_at	-0.369	8.420	-2.817	1.286e-02	0.376	-2.856	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	NM_002375	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
213131_at	-0.676	6.098	-2.817	1.288e-02	0.376	-2.857	OLFM1	olfactomedin 1	9	137106909, 137106923	R38389	10439	9q34.3	Hs.522484	9	protein binding endoplasmic reticulum endoplasmic reticulum lumen multicellular organismal development nervous system development membrane
242757_at	-0.249	4.506	-2.817	1.288e-02	0.376	-2.857	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	6	-37708261	BE730067	266727	6p21	Hs.437993	6	neuron migration molecular_function plasma membrane multicellular organismal development nervous system development brain development spinal cord association neuron differentiation cell differentiation anchored to plasma membrane
218858_at	-0.545	9.627	-2.816	1.289e-02	0.377	-2.858	DEPDC6	DEP domain containing 6	8	120955080	NM_022783	64798	8q24.12	Hs.112981	11	protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size
209183_s_at	0.596	7.160	2.814	1.294e-02	0.377	-2.861	C10orf10	chromosome 10 open reading frame 10	10	-44791714	AL136653	11067	10q11.21	Hs.93675	14	mitochondrion
1565620_at	0.385	6.017	2.814	1.294e-02	0.377	-2.861	AGAP4	ArfGAP with GTPase domain, ankyrin repeat and PH domain 4	10	-45641055	BG621044	119016	10q11.22	Hs.656384	1	ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding
1552506_at	0.194	3.694	2.814	1.295e-02	0.377	-2.862	CRB2	crumbs homolog 2 (Drosophila)	9	125158268	NM_173689	286204	9q33.3	Hs.710092	7	calcium ion binding extracellular region plasma membrane visual perception integral to membrane response to stimulus
205590_at	0.312	2.619	2.814	1.295e-02	0.377	-2.862	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	15	-36567593	NM_005739	10125	15q14	Hs.591127	21	guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular membrane fraction cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane Ras protein signal transduction zinc ion binding diacylglycerol binding cell differentiation regulation of small GTPase mediated signal transduction	MAPK signaling pathway T cell receptor signaling pathway
213718_at	-0.315	5.584	-2.813	1.296e-02	0.378	-2.863	RBM4	RNA binding motif protein 4	11	66162713	BE222257	5936	11q13	Hs.533712	20	nucleotide binding RNA binding nucleus nucleolus cytoplasm mRNA processing zinc ion binding RNA splicing metal ion binding
230904_at	-0.627	5.557	-2.813	1.297e-02	0.378	-2.863	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	W42665	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
230249_at	-0.854	5.937	-2.812	1.299e-02	0.378	-2.865	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	8	136538897	AI650382	10656	8q24.2	Hs.444558	20	RNA binding protein binding nucleus nucleolus cytoplasm spermatogenesis SH3 domain binding regulation of transcription
214434_at	0.313	5.592	2.812	1.300e-02	0.378	-2.865	HSPA12A	heat shock 70kDa protein 12A	10	-118420692	AB007877	259217	10q26.12	Hs.654682	8	nucleotide binding ATP binding
211110_s_at	-0.478	6.035	-2.812	1.300e-02	0.378	-2.865	AR	androgen receptor	X	66680598, 66705407	AF162704	367	Xq11.2-q12	Hs.496240	1010	in utero embryonic development transcription factor activity receptor activity androgen receptor activity androgen receptor activity receptor binding androgen binding nucleus cytoplasm transport signal transduction cell-cell signaling sex differentiation cell death zinc ion binding cell proliferation male gonad development cell growth male somatic sex determination androgen receptor signaling pathway prostate gland development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter metal ion binding protein dimerization activity regulation of catalytic activity	Pathways in cancer Prostate cancer
231836_at	0.431	5.249	2.811	1.302e-02	0.378	-2.866	HKR1	GLI-Kruppel family member HKR1	19	42517419	BC004513	284459	19q13.12	Hs.657027	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding metal ion binding
221884_at	0.372	5.524	2.811	1.302e-02	0.378	-2.866	MECOM	MDS1 and EVI1 complex locus	3	-170283980, -170283980, -170283980, -170283980	BE466525	2122	3q24-q28	Hs.659873 Hs.719216	46	molecular_function DNA binding transcription factor activity protein binding intracellular nucleus multicellular organismal development biological_process zinc ion binding metal ion binding	MAPK signaling pathway Pathways in cancer Chronic myeloid leukemia
222990_at	-0.245	9.423	-2.811	1.303e-02	0.378	-2.867	UBQLN1	ubiquilin 1	9	-85464697	AW204104	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
1555852_at	0.596	4.364	2.811	1.303e-02	0.378	-2.867	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	6	32929915, 4202792, 4007991	AI375915	5698	6p21.3	Hs.654585	72	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex immune response peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
202660_at	0.423	4.807	2.811	1.303e-02	0.378	-2.868	ITPR2	inositol 1,4,5-triphosphate receptor, type 2	12	-26379551	AA834576	3709	12p11	Hs.512235	22	response to hypoxia plasma membrane enriched fraction ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding cytoplasm microsome cell cortex ion transport calcium ion transport signal transduction calcium ion transmembrane transporter activity membrane integral to membrane sarcoplasmic reticulum membrane phosphoinositide binding	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease
227298_at	0.270	5.515	2.811	1.303e-02	0.378	-2.868	FLJ37798	hypothetical gene supported by AK095117	6		AI806330	401264	6p12.3	Hs.544586	1
202661_at	0.255	3.582	2.810	1.304e-02	0.378	-2.868	ITPR2	inositol 1,4,5-triphosphate receptor, type 2	12	-26379551	AI963873	3709	12p11	Hs.512235	22	response to hypoxia plasma membrane enriched fraction ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding cytoplasm microsome cell cortex ion transport calcium ion transport signal transduction calcium ion transmembrane transporter activity membrane integral to membrane sarcoplasmic reticulum membrane phosphoinositide binding	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease
1555783_x_at	0.257	5.164	2.810	1.305e-02	0.378	-2.868	PQLC2	PQ loop repeat containing 2	1	19511326	BC015324	54896	1p36.13	Hs.647620	5	membrane integral to membrane
212350_at	-0.664	7.557	-2.810	1.305e-02	0.378	-2.869	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	AB029031	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
225379_at	-0.327	8.104	-2.809	1.308e-02	0.378	-2.871	MAPT	microtubule-associated protein tau	17	41327543	AA199717	4137	17q21.1	Hs.101174	545	microtubule cytoskeleton organization microtubule cytoskeleton organization structural constituent of cytoskeleton cytoplasm cytosol cytoskeleton microtubule microtubule associated complex plasma membrane plasma membrane negative regulation of microtubule depolymerization microtubule binding microtubule binding lipoprotein binding SH3 domain binding enzyme binding axon axon growth cone growth cone positive regulation of microtubule polymerization positive regulation of microtubule polymerization apolipoprotein E binding identical protein binding cell projection tubulin complex tubulin complex positive regulation of axon extension positive regulation of axon extension generation of neurons	MAPK signaling pathway Alzheimer's disease
205495_s_at	0.441	4.997	2.808	1.309e-02	0.378	-2.872	GNLY	granulysin	2	85774924	NM_006433	10578	2p11.2	Hs.105806	36	extracellular region extracellular space xenobiotic metabolic process cellular defense response defense response to bacterium defense response to fungus
1557122_s_at	0.203	3.477	2.805	1.319e-02	0.380	-2.878	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	5	-160648013	BC036592	2561	5q34	Hs.303527	47	GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport gamma-aminobutyric acid signaling pathway synaptic transmission cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
218364_at	-0.432	8.099	-2.804	1.322e-02	0.381	-2.880	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	NM_017724	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
212845_at	-0.379	10.495	-2.803	1.323e-02	0.381	-2.881	SAMD4A	sterile alpha motif domain containing 4A	14	54104386, 54291255	AB028976	23034	14q22.2	Hs.98259	4	cytoplasm synaptosome translation repressor activity dendrite positive regulation of translation
218471_s_at	0.264	6.786	2.803	1.323e-02	0.381	-2.881	BBS1	Bardet-Biedl syndrome 1	11	66034694	NM_024649	582	11q13.1	Hs.502915	22	microtubule cytoskeleton organization retina homeostasis protein binding cytoplasm plasma membrane sensory perception of smell photoreceptor cell morphogenesis flagellum assembly fertilization dendrite development striatum development hippocampus development cerebral cortex development adult behavior motile secondary cilium BBSome sensory cilium assembly multicellular organism growth olfactory behavior hormone metabolic process cellular lipid metabolic process fat cell differentiation photoreceptor cell maintenance brain morphogenesis response to stimulus cilium membrane cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility
219296_at	0.340	3.900	2.803	1.324e-02	0.381	-2.882	ZDHHC13	zinc finger, DHHC-type containing 13	11	19095267	NM_019028	54503	11p15.1	Hs.188569	6	signal transducer activity zinc ion binding acyltransferase activity membrane integral to membrane transferase activity positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
216252_x_at	-0.409	4.056	-2.803	1.325e-02	0.381	-2.882	FAS	Fas (TNF receptor superfamily, member 6)	10	90740267, 90740267	Z70519	355	10q24.1	Hs.244139	589	immunoglobulin production renal system process transmembrane receptor activity extracellular region soluble fraction cytosol plasma membrane plasma membrane protein complex assembly anti-apoptosis activation-induced cell death of T cells inflammatory cell apoptosis transformed cell apoptosis immune response signal transduction induction of apoptosis via death domain receptors activation of pro-apoptotic gene products response to toxin external side of plasma membrane gene expression positive regulation of necrotic cell death integral to membrane B cell mediated immunity kinase binding death-inducing signaling complex identical protein binding negative thymic T cell selection regulation of lymphocyte differentiation regulation of myeloid cell differentiation spleen development negative regulation of B cell activation protein homooligomerization response to glucocorticoid stimulus response to protein stimulus	MAPK signaling pathway Cytokine-cytokine receptor interaction p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Type I diabetes mellitus Alzheimer's disease Pathways in cancer Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
218127_at	-0.608	7.185	-2.802	1.328e-02	0.381	-2.884	NFYB	nuclear transcription factor Y, beta	12	-103034987	AI804118	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
1558934_a_at	0.319	3.396	2.801	1.328e-02	0.381	-2.885	GTF2H5	general transcription factor IIH, polypeptide 5	6	158509366	AL134162	404672	6q25.3	Hs.356224	11	DNA binding nucleus nucleotide-excision repair response to DNA damage stimulus regulation of transcription	Nucleotide excision repair
1566134_at	0.282	6.179	2.801	1.329e-02	0.381	-2.885	CARHSP1	calcium regulated heat stable protein 1, 24kDa	16	-8854302, -8854302	AL832316	23589	16p13.2	Hs.632184	13	DNA binding protein binding cytoplasm regulation of transcription, DNA-dependent intracellular signaling cascade phosphatase binding
205584_at	-0.267	6.114	-2.801	1.329e-02	0.381	-2.885	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_024810	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
232662_x_at	0.338	7.435	2.801	1.331e-02	0.381	-2.886	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	AK022598	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
238784_at	0.410	3.311	2.800	1.331e-02	0.381	-2.886	DPY19L2	dpy-19-like 2 (C. elegans)	12	-62238959	AI039361	283417	12q14.2	Hs.533644	4	membrane integral to membrane
218699_at	0.299	6.389	2.800	1.332e-02	0.381	-2.887	RAB7L1	RAB7, member RAS oncogene family-like 1	1	-204003737	BG338251	8934	1q32	Hs.115325	8	nucleotide binding GTPase activity protein binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport
219777_at	0.451	7.326	2.800	1.333e-02	0.381	-2.887	GIMAP6	GTPase, IMAP family member 6	7	-149953398	NM_024711	474344		Hs.647105	7	nucleotide binding GTP binding
1554479_a_at	-0.402	7.175	-2.800	1.333e-02	0.381	-2.888	CARD8	caspase recruitment domain family, member 8	19	-53403154	AF511652	22900	19q13.33	Hs.446146 Hs.655940	23	protein binding intracellular nucleus cytoplasm caspase activator activity NACHT domain binding protein homodimerization activity regulation of apoptosis negative regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of caspase activity positive regulation of interleukin-1 beta secretion
1557120_at	0.590	5.319	2.799	1.334e-02	0.381	-2.888	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	BE622780	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
1558305_at	-0.258	2.479	-2.799	1.335e-02	0.381	-2.889	GIGYF2	GRB10 interacting GYF protein 2	2	233270258	BC029456	26058	2q37.1	Hs.565319	23	protein binding
235648_at	0.405	4.526	2.798	1.337e-02	0.381	-2.890	ZNF567	zinc finger protein 567	19	41872141	AA742659	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235635_at	-0.332	5.358	-2.798	1.337e-02	0.381	-2.891	ARHGAP5	Rho GTPase activating protein 5	14	31616245	N50119	394	14q12	Hs.592313	19	GTPase activity GTPase activator activity Rho GTPase activator activity GTP binding intracellular cytoplasm cell adhesion signal transduction small GTPase mediated signal transduction Rho protein signal transduction membrane SH2 domain binding	Focal adhesion Leukocyte transendothelial migration
224336_s_at	-0.339	5.069	-2.797	1.339e-02	0.381	-2.892	DUSP16	dual specificity phosphatase 16	12	-12520097	AB052156	80824	12p13	Hs.536535	12	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive	MAPK signaling pathway
230389_at	0.375	5.740	2.797	1.339e-02	0.381	-2.892	FNBP1	formin binding protein 1	9	-131689286	BE046511	23048	9q34	Hs.189409	25	cytoplasm lysosome cytoskeleton plasma membrane cell cortex endocytosis lipid binding cytoplasmic vesicle identical protein binding
235910_x_at	0.311	4.300	2.797	1.341e-02	0.382	-2.893	ZNF316	zinc finger protein 316	7		BE674951	100131017	7p22.1	Hs.112668	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552316_a_at	0.492	5.203	2.796	1.342e-02	0.382	-2.894	GIMAP1	GTPase, IMAP family member 1	7	150044630	NM_130759	170575	7q36.1	Hs.647087	7	GTP binding endoplasmic reticulum membrane integral to membrane
202371_at	0.418	9.462	2.796	1.344e-02	0.382	-2.895	TCEAL4	transcription elongation factor A (SII)-like 4	X	102727074	NM_024863	79921	Xq22.2	Hs.194329	10	nucleus regulation of transcription
225803_at	-0.960	10.166	-2.795	1.345e-02	0.382	-2.895	FBXO32	F-box protein 32	8	-124584538, -124584538	AW006123	114907	8q24.13	Hs.403933	17	protein binding modification-dependent protein catabolic process
219778_at	-0.674	7.658	-2.795	1.346e-02	0.382	-2.896	ZFPM2	zinc finger protein, multitype 2	8	106400322	NM_012082	23414	8q23	Hs.431009	16	negative regulation of transcription from RNA polymerase II promoter vasculogenesis in utero embryonic development DNA binding RNA polymerase II transcription factor activity transcription corepressor activity intracellular nucleus cytoplasm transcription factor binding zinc ion binding lung development regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding embryonic organ development cardiac muscle tissue development
225243_s_at	-0.511	8.469	-2.795	1.346e-02	0.382	-2.896	SLMAP	sarcolemma associated protein	3	57718213	AB046821	7871	3p21.2-p14.3	Hs.476432	11	smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding
209316_s_at	-0.401	8.606	-2.794	1.347e-02	0.382	-2.897	HBS1L	HBS1-like (S. cerevisiae)	6	-135398687, -135323215, -135323213	BC001465	10767	6q23-q24	Hs.378532	12	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation signal transduction
1564679_at	-0.750	6.700	-2.794	1.349e-02	0.382	-2.898	ASB15	ankyrin repeat and SOCS box-containing 15	7	123036347	AF403033	142685	7q31.31	Hs.83916	6	intracellular signaling cascade modification-dependent protein catabolic process
217726_at	-0.311	7.621	-2.793	1.351e-02	0.382	-2.900	COPZ1	coatomer protein complex, subunit zeta 1	12	53005177	NM_016057	22818	12q13.2-q13.3	Hs.505652	14	protein binding cytoplasm Golgi apparatus cytosol intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat COPI vesicle coat cytoplasmic vesicle COPI coating of Golgi vesicle
212062_at	0.422	7.052	2.793	1.352e-02	0.382	-2.900	ATP9A	ATPase, class II, type 9A	20	-49646720	AB014511	10079	20q13.2	Hs.719117	6	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
228438_at	0.605	3.703	2.792	1.355e-02	0.383	-2.902	LOC100132891	hypothetical protein LOC100132891	8		AI948599	100132891	8q13.3	Hs.137674
227840_at	0.364	5.525	2.791	1.356e-02	0.383	-2.903	C2orf76	chromosome 2 open reading frame 76	2	-119776489	AA738440	130355	2q14.2	Hs.99488	1
218628_at	-0.427	8.227	-2.791	1.356e-02	0.383	-2.903	CCDC53	coiled-coil domain containing 53	12	-100930847	NM_016053	51019	12q23.2	Hs.405692	9	molecular_function protein binding cellular_component biological_process
232269_x_at	-0.288	6.918	-2.791	1.357e-02	0.383	-2.904	METRN	meteorin, glial cell differentiation regulator	16	705173	BE965311	79006	16p13.3	Hs.533772	6	extracellular region extracellular space multicellular organismal development nervous system development glial cell differentiation positive regulation of axonogenesis
218781_at	-0.256	5.880	-2.789	1.361e-02	0.383	-2.906	SMC6	structural maintenance of chromosomes 6	2	-17708559	NM_024624	79677	2p24.2	Hs.526728	15	nucleotide binding ATP binding intracellular nucleus chromosome DNA repair DNA recombination response to DNA damage stimulus
208752_x_at	-0.389	9.727	-2.789	1.361e-02	0.383	-2.906	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AI888672	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
217792_at	-0.373	7.816	-2.789	1.363e-02	0.383	-2.907	SNX5	sorting nexin 5	20	-17870243, -17870243	NM_014426	27131	20p11	Hs.316890	14	protein binding cell communication protein transport phosphoinositide binding
204011_at	-0.321	6.771	-2.788	1.366e-02	0.384	-2.909	SPRY2	sprouty homolog 2 (Drosophila)	13	-79808112	NM_005842	10253	13q31.1	Hs.18676	59	protein binding cytoplasm cytosol microtubule plasma membrane plasma membrane cell-cell signaling multicellular organismal development sensory perception of sound organ morphogenesis regulation of signal transduction lung development inner ear morphogenesis negative regulation of MAP kinase activity cell fate commitment branching morphogenesis of a tube	Jak-STAT signaling pathway
201014_s_at	-0.457	6.343	-2.786	1.370e-02	0.385	-2.912	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	4	56996671, 56997025	NM_006452	10606	4q12	Hs.518774 Hs.709570	16	nucleotide binding phosphoribosylaminoimidazole carboxylase activity phosphoribosylaminoimidazolesuccinocarboxamide synthase activity ATP binding purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process purine base biosynthetic process lyase activity ligase activity identical protein binding	Purine metabolism Metabolic pathways
232936_at	-0.480	7.577	-2.786	1.370e-02	0.385	-2.912	KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7	19	-54262486	AJ310479	3743	19q13.3	Hs.306973	5	voltage-gated ion channel activity voltage-gated potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex membrane integral to membrane potassium ion binding
226490_at	0.357	3.681	2.786	1.370e-02	0.385	-2.912	NHSL1	NHS-like 1	6	-138784873, -138784873	AA503387	57224	6q23.3	Hs.652741	3
229294_at	0.243	2.578	2.785	1.372e-02	0.385	-2.913	JPH3	junctophilin 3	16	86193999	AL537395	57338	16q24.3	Hs.592068	18	molecular_function protein binding endoplasmic reticulum plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
206510_at	-0.703	6.218	-2.784	1.375e-02	0.386	-2.915	SIX2	SIX homeobox 2	2	-45085828	AF332197	10736	2p16-p15	Hs.101937	10	metanephros development transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent protein import into nucleus multicellular organismal development middle ear morphogenesis sequence-specific DNA binding negative regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
200721_s_at	-0.282	7.848	-2.784	1.375e-02	0.386	-2.915	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	10	-104228976	NM_005736	10121	10q24.32	Hs.153961	26	nucleotide binding protein binding ATP binding cytoplasm centrosome cytoskeleton dynactin complex vesicle-mediated transport
203912_s_at	-0.360	9.011	-2.784	1.377e-02	0.386	-2.916	DNASE1L1	deoxyribonuclease I-like 1	X	-153282772, -153282772	NM_006730	1774	Xq28	Hs.401929	14	DNA binding endonuclease activity deoxyribonuclease activity endoplasmic reticulum DNA catabolic process hydrolase activity
224478_s_at	0.443	7.075	2.783	1.377e-02	0.386	-2.917	C7orf50	chromosome 7 open reading frame 50	7	-1003148	BC006224	84310	7p22.3	Hs.653258	5
222514_at	-0.449	7.213	-2.783	1.380e-02	0.386	-2.918	RRAGC	Ras-related GTP binding C	1	-39077605	AK023373	64121	1p34	Hs.532461	8	nucleotide binding magnesium ion binding GTPase activity protein binding GTP binding nucleus cytoplasm transcription apoptosis small GTPase mediated signal transduction RNA splicing cell growth GDP binding protein heterodimerization activity
227705_at	0.862	5.007	2.782	1.381e-02	0.386	-2.919	TCEAL7	transcription elongation factor A (SII)-like 7	X	102471820	BF591534	56849	Xq22.1	Hs.21861	7	nucleus regulation of transcription
213355_at	-1.058	6.136	-2.782	1.382e-02	0.386	-2.919	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	3	99934261	AI989567	10402	3q12.1	Hs.148716	5	Golgi apparatus amino sugar metabolic process protein amino acid glycosylation glycolipid metabolic process sialyltransferase activity protein lipoylation membrane integral to membrane integral to Golgi membrane	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
201667_at	0.473	7.602	2.781	1.383e-02	0.386	-2.920	GJA1	gap junction protein, alpha 1, 43kDa	6	121798443	NM_000165	2697	6q21-q23.2	Hs.74471	181	signal transducer activity protein binding cytoplasm mitochondrial outer membrane lysosome early endosome multivesicular body endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane integral to plasma membrane fascia adherens connexon complex apoptosis muscle contraction cell-cell signaling heart development negative regulation of cell proliferation response to pH vascular transport ion transmembrane transporter activity ATP transport gap junction assembly SH3 domain binding transmembrane transporter activity cell junction PDZ domain binding Golgi-associated vesicle membrane positive regulation of I-kappaB kinase/NF-kappaB cascade membrane raft positive regulation of protein catabolic process neuron projection morphogenesis protein oligomerization regulation of calcium ion transport	Gap junction Arrhythmogenic right ventricular cardiomyopathy (ARVC)
208089_s_at	-0.470	5.503	-2.781	1.384e-02	0.386	-2.921	TDRD3	tudor domain containing 3	13	59868591, 59869427	NM_030794	81550	13q21.2	Hs.525061	12	nucleic acid binding nucleus cytoplasm
203313_s_at	-0.448	4.866	-2.781	1.386e-02	0.386	-2.922	TGIF1	TGFB-induced factor homeobox 1	18	3402071, 3437607, 3439972, 3440030, 3440171, 3441590, 3443771	NM_003244	7050	18p11.3	Hs.373550	38	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription corepressor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding
224298_s_at	-0.375	7.624	-2.780	1.386e-02	0.386	-2.922	UBAC2	UBA domain containing 2	13	98650679, 98651163	BC004528	337867	13q32.3	Hs.508545	6	membrane integral to membrane
1558689_a_at	0.205	3.184	2.779	1.390e-02	0.387	-2.925	LOC441461	hypothetical LOC441461	9		BG701300	441461	9q31.1	Hs.163155	1
218675_at	0.279	5.218	2.778	1.392e-02	0.387	-2.926	SLC22A17	solute carrier family 22, member 17	14	-22885378, -22885366	NM_020372	51310	14q11.2	Hs.373498	6	transporter activity ion transport membrane integral to membrane
204066_s_at	0.423	6.021	2.778	1.393e-02	0.387	-2.927	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	2	236067474	NM_014914	116987	2q37	Hs.435039	11	nucleotide binding GTP binding intracellular cytoplasm small GTPase mediated signal transduction ARF GTPase activator activity zinc ion binding protein transport regulation of ARF GTPase activity metal ion binding	Endocytosis
1569936_a_at	0.279	4.066	2.777	1.394e-02	0.387	-2.928	ZNF664	zinc finger protein 664	12	123023622	BC033539	144348	12q24.31	Hs.524828	8	molecular_function DNA binding cellular_component intracellular nucleus biological_process zinc ion binding regulation of transcription metal ion binding
205896_at	0.480	4.695	2.776	1.398e-02	0.388	-2.930	SLC22A4	solute carrier family 22 (organic cation/ergothioneine transporter), member 4	5	131658043	NM_003059	6583	5q31.1	Hs.310591	79	nucleotide binding transporter activity protein binding ATP binding mitochondrion plasma membrane integral to plasma membrane triglyceride metabolic process ion transport sodium ion transport body fluid secretion secondary active organic cation transmembrane transporter activity carnitine metabolic process ion transmembrane transporter activity carnitine transporter activity symporter activity cation:cation antiporter activity quaternary ammonium group transport carnitine transport apical plasma membrane PDZ domain binding sodium ion binding
201136_at	-0.560	7.879	-2.775	1.400e-02	0.388	-2.931	PLP2	proteolipid protein 2 (colonic epithelium-enriched)	X	48915216	NM_002668	5355	Xp11.23	Hs.77422	12	protein binding membrane fraction endoplasmic reticulum endoplasmic reticulum membrane plasma membrane ion transport chemotaxis ion transmembrane transporter activity integral to membrane cytokine-mediated signaling pathway chemokine binding
222448_s_at	-0.434	7.474	-2.774	1.403e-02	0.389	-2.933	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	1	47572055	AF112216	51727	1p32	Hs.714325	16	nucleotide binding cytidylate kinase activity uridine kinase activity ATP binding nucleus cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine ribonucleotide biosynthetic process transferase activity phosphotransferase activity, phosphate group as acceptor	Pyrimidine metabolism Metabolic pathways
210395_x_at	0.238	6.625	2.774	1.404e-02	0.389	-2.934	MYL4	myosin, light chain 4, alkali; atrial, embryonic	17	42641426, 42641712	AF116676	4635	17q21-qter	Hs.463300	21	regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex muscle organ development structural constituent of muscle myosin complex A band myosin II heavy chain binding positive regulation of ATPase activity actin filament binding cardiac muscle contraction	Cardiac muscle contraction
222202_at	-0.182	2.235	-2.774	1.405e-02	0.389	-2.935	LOC644213	glyceraldehyde-3-phosphate dehydrogenase pseudogene	1		AK024355	644213	1p12	Hs.647686
1562743_at	0.307	4.691	2.772	1.409e-02	0.390	-2.937	ZNF33B	zinc finger protein 33B	10	-42404560	BC042873	7582	10q11.2	Hs.499453	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213832_at	0.492	5.595	2.772	1.410e-02	0.390	-2.938	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	1	-112119976	AA530995	3752	1p13.3	Hs.666367	23	voltage-gated ion channel activity voltage-gated potassium channel activity A-type (transient outward) potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex zinc ion binding potassium ion binding sarcolemma neuron projection cell soma metal ion binding
208466_at	0.228	4.300	2.771	1.411e-02	0.390	-2.938	RAB3D	RAB3D, member RAS oncogene family	19	-11296092	NM_004283	9545	19p13.2	Hs.655274	13	nucleotide binding GTPase activity protein binding GTP binding plasma membrane exocytosis small GTPase mediated signal transduction protein transport
1559705_s_at	0.199	5.647	2.771	1.412e-02	0.390	-2.938	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	X73875	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
225140_at	-0.324	3.678	-2.771	1.413e-02	0.390	-2.939	KLF3	Kruppel-like factor 3 (basic)	4	38342184	BF438116	51274	4p14	Hs.298658	12	transcription factor activity intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
219213_at	0.375	6.066	2.770	1.415e-02	0.390	-2.940	JAM2	junctional adhesion molecule 2	21	25933459	NM_021219	58494	21q21.2	Hs.517227	21	plasma membrane plasma membrane integral to plasma membrane tight junction cell-cell adhesion cell junction	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
220391_at	0.261	3.010	2.770	1.416e-02	0.390	-2.941	ZBTB3	zinc finger and BTB domain containing 3	11	-62275012	NM_024784	79842	11q12.3	Hs.147554	5	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
210250_x_at	-0.402	10.180	-2.768	1.420e-02	0.391	-2.944	ADSL	adenylosuccinate lyase	22	39072449	AF067854	158	22q13.1 22q13.2	Hs.75527	29	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity cytoplasm cytosol AMP biosynthetic process purine ribonucleotide biosynthetic process lyase activity protein tetramerization (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
218584_at	0.286	6.253	2.768	1.421e-02	0.392	-2.945	TCTN1	tectonic family member 1	12	109536262	NM_024549	79600	12q24.11	Hs.211511 Hs.694390	5	extracellular region multicellular organismal development
214002_at	-0.293	6.425	-2.767	1.426e-02	0.392	-2.947	MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	12	54838366	AA419227	4637	12q13.2	Hs.632717	12	motor activity calcium ion binding skeletal muscle tissue development structural constituent of muscle unconventional myosin complex muscle filament sliding actin-dependent ATPase activity	Vascular smooth muscle contraction
218346_s_at	-0.667	9.086	-2.766	1.426e-02	0.392	-2.947	SESN1	sestrin 1	6	-109414337	NM_014454	27244	6q21	Hs.591336	6	nucleus response to DNA damage stimulus cell cycle arrest negative regulation of cell proliferation	p53 signaling pathway
203478_at	0.173	11.672	2.766	1.426e-02	0.392	-2.948	NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	4	-140430540	NM_002494	4717	4q28.2-q31.1	Hs.84549	8	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
201604_s_at	-0.347	6.274	-2.766	1.426e-02	0.392	-2.948	PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	12	-78691474, -78691474, -78691474	NM_002480	4659	12q15-q21	Hs.49582	41	signal transducer activity protein binding cytoplasm	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton
225836_s_at	0.427	3.744	2.766	1.426e-02	0.392	-2.948	C12orf32	chromosome 12 open reading frame 32	12	2856625	AL528840	83695	12p13.33	Hs.198853	6
233561_at	0.238	2.547	2.765	1.431e-02	0.392	-2.951	SH3TC2	SH3 domain and tetratricopeptide repeats 2	5	-148341905	AK023641	79628	5q32	Hs.483784	15	binding
221486_at	-0.448	9.846	-2.764	1.433e-02	0.392	-2.952	ENSA	endosulfine alpha	1	-148866145, -148862377, -148862377, -148861222, -148861222	AF067170	2029	1q21.3	Hs.632456	15	receptor binding cytoplasm transport response to nutrient ion channel inhibitor activity
227796_at	-0.322	6.329	-2.764	1.433e-02	0.392	-2.952	ZFP62	zinc finger protein 62 homolog (mouse)	5	-180207218, -12668	AW157773	643836	5q35.3	Hs.509227 Hs.719290	6	nucleic acid binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
204706_at	0.264	6.578	2.764	1.434e-02	0.392	-2.952	INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	9	-138442892	NM_019892	56623	9q34.3	Hs.120998	5	Golgi membrane inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity cellular_component Golgi apparatus lipid metabolic process biological_process membrane hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
222538_s_at	-0.642	8.000	-2.764	1.434e-02	0.392	-2.953	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	3	57236804	AW467472	26060	3p21.1-p14.3	Hs.476415	23	protein binding nucleus cytoplasm endosome microsome cytosol cell cycle signal transduction cell proliferation insulin receptor signaling pathway endosome membrane vesicle membrane membrane NuRD complex protein kinase B binding regulation of glucose import regulation of establishment of protein localization	Pathways in cancer Colorectal cancer
228304_at	0.524	5.051	2.764	1.434e-02	0.392	-2.953	RBM43	RNA binding motif protein 43	2	-151812974	BE674118	375287	2q23.3	Hs.302442	3	RNA binding
1557455_s_at	-0.518	5.701	-2.763	1.435e-02	0.392	-2.953	MOSPD1	motile sperm domain containing 1	X	-133849327	AF086333	56180	Xq26.3	Hs.590789	4	structural molecule activity membrane integral to membrane
224573_at	0.272	10.494	2.763	1.435e-02	0.392	-2.953	RNASEK	ribonuclease, RNase K	17	6856521	BE744389	440400	17p13.1	Hs.632232	3	endoribonuclease activity cellular_component rRNA transcription membrane integral to membrane hydrolase activity
223334_at	0.404	10.036	2.763	1.436e-02	0.392	-2.954	TMEM126A	transmembrane protein 126A	11	85036692	AL136941	84233	11q14.1	Hs.533725	8	molecular_function mitochondrion biological_process membrane integral to membrane
1552611_a_at	0.486	7.876	2.762	1.438e-02	0.393	-2.955	JAK1	Janus kinase 1	1	-65071493	AL555086	3716	1p32.3-p31.3	Hs.207538	118	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity growth hormone receptor binding protein binding ATP binding nucleus cytoplasm cytoskeleton enzyme linked receptor protein signaling pathway protein kinase cascade membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway response to antibiotic	Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer
227005_at	0.604	8.951	2.762	1.439e-02	0.393	-2.955	RPP14	ribonuclease P/MRP 14kDa subunit	3	58267011, 58267013	BF439230	11102	3p14.3	Hs.446320 Hs.700016	14	RNA binding ribonuclease P activity ribonuclease activity nucleus tRNA processing hydrolase activity identical protein binding
220734_s_at	-0.325	7.324	-2.762	1.440e-02	0.393	-2.956	GLTPD1	glycolipid transfer protein domain containing 1	1	1250005	NM_030575	80772	1p36.33	Hs.515689	1	cytoplasm glycolipid transporter activity glycolipid transport glycolipid binding
203525_s_at	-0.517	7.366	-2.762	1.440e-02	0.393	-2.956	APC	adenomatous polyposis coli	5	112071116, 112101454	AI375486	324	5q21-q22	Hs.158932	386	cytokinesis after mitosis kinetochore kidney development hair follicle development nucleus cytoplasm centrosome cytosol cytoplasmic microtubule protein complex assembly response to DNA damage stimulus negative regulation of microtubule depolymerization cell cycle arrest mitotic metaphase/anaphase transition mitotic cell cycle spindle assembly checkpoint axonogenesis beta-catenin binding microtubule binding axis specification anterior/posterior pattern formation dorsal/ventral pattern formation proximal/distal pattern formation lateral plasma membrane protein kinase regulator activity protein kinase binding negative regulation of Wnt receptor signaling pathway positive regulation of cell migration growth cone positive regulation of epithelial cell differentiation beta-catenin destruction complex positive regulation of microtubule polymerization cell projection membrane positive regulation of pseudopodium assembly T cell differentiation in the thymus axon part Axin-APC-beta-catenin-GSK3B complex somatic stem cell maintenance negative regulation of odontogenesis cell projection positive regulation of apoptosis negative regulation of apoptosis negative regulation of MAPKKK cascade skin development regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process negative regulation of cyclin-dependent protein kinase activity positive regulation of cell adhesion muscle maintenance thymus development negative regulation of epithelial cell proliferation regulation of nitrogen compound metabolic process chromosome organization regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye Wnt receptor signaling pathway through beta-catenin Wnt receptor signaling pathway through beta-catenin	Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma
1555905_a_at	-0.915	4.532	-2.760	1.444e-02	0.393	-2.959	C3orf23	chromosome 3 open reading frame 23	3	44354614, 44354947, 44354947	AI147556	285343	3p21.31	Hs.55131	8	mitochondrion
234129_at	-0.232	3.328	-2.760	1.445e-02	0.393	-2.959	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	11	119713155	AL137456	23365	11q23.3	Hs.24598	26	G-protein-coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm G-protein coupled receptor protein signaling pathway intracellular signaling cascade membrane regulation of Rho protein signal transduction	Vascular smooth muscle contraction Axon guidance Regulation of actin cytoskeleton
202980_s_at	-0.443	5.526	-2.759	1.446e-02	0.393	-2.960	SIAH1	seven in absentia homolog 1 (Drosophila)	16	-46951954, -46951946	AI953523	6477	16q12	Hs.295923	64	ubiquitin-protein ligase activity nucleus cytoplasm proteolysis ubiquitin-dependent protein catabolic process apoptosis cell cycle multicellular organismal development spermatogenesis nervous system development axon guidance protein C-terminus binding zinc ion binding anatomical structure morphogenesis protein ubiquitination ligase activity cell differentiation metal ion binding	p53 signaling pathway Ubiquitin mediated proteolysis Wnt signaling pathway
241405_at	-0.413	5.644	-2.759	1.448e-02	0.394	-2.961	LOC400604	hypothetical gene supported by BC039664	17		AI085535	400604	17q21.33	Hs.641441	1
212228_s_at	-0.342	10.592	-2.758	1.449e-02	0.394	-2.962	COQ9	coenzyme Q9 homolog (S. cerevisiae)	16	56038902	AC004382	57017	16q21	Hs.513632	7	mitochondrion ubiquinone biosynthetic process
200008_s_at	-0.662	7.612	-2.758	1.450e-02	0.394	-2.962	GDI2	GDP dissociation inhibitor 2	10	-5847191	D13988	2665	10p15	Hs.299055	16	Rab GDP-dissociation inhibitor activity GTPase activator activity cytoplasm signal transduction cell surface protein transport membrane regulation of GTPase activity
204741_at	0.278	5.969	2.757	1.452e-02	0.394	-2.964	BICD1	bicaudal D homolog 1 (Drosophila)	12	32151451	NM_001714	636	12p11.2-p11.1	Hs.505202	17	structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis
202518_at	-0.327	7.330	-2.757	1.454e-02	0.395	-2.965	BCL7B	B-cell CLL/lymphoma 7B	7	-72588621	NM_001707	9275	7q11.23	Hs.647051	8	actin binding cellular_component biological_process
201361_at	-0.257	7.562	-2.756	1.457e-02	0.395	-2.966	TMEM109	transmembrane protein 109	11	60437946	NM_024092	79073	11q12.2	Hs.13662	5	molecular_function cellular_component nucleus nucleolus cytoplasm biological_process membrane integral to membrane sarcoplasmic reticulum nuclear membrane
226905_at	0.474	7.645	2.756	1.457e-02	0.395	-2.967	FAM101B	family with sequence similarity 101, member B	17	-289998	BG036514	359845	17p13	Hs.345588 Hs.596411 Hs.719324	4
239462_at	0.306	5.274	2.755	1.460e-02	0.395	-2.968	ZNF284	zinc finger protein 284	19	49268136	AI559740	342909	19q13.31	Hs.279840 Hs.445395	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
216100_s_at	-0.778	4.756	-2.755	1.460e-02	0.395	-2.968	TOR1AIP1	torsin A interacting protein 1	1	178118042	BG289527	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
1555248_a_at	-0.273	3.199	-2.754	1.462e-02	0.395	-2.969	WNK3	WNK lysine deficient protein kinase 3	X	-54239579	AY082340	65267	Xp11.23-p11.21	Hs.92423	12	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation protein kinase cascade transferase activity
230612_at	0.277	4.758	2.754	1.463e-02	0.395	-2.970	WDR73	WD repeat domain 73	15	-82987014	AI264119	84942	15q25.2	Hs.719288	3
206544_x_at	-0.561	7.914	-2.753	1.464e-02	0.395	-2.971	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	NM_003070	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
219660_s_at	0.372	3.738	2.753	1.465e-02	0.395	-2.971	ATP8A2	ATPase, aminophospholipid transporter-like, class I, type 8A, member 2	13	24844208	NM_016529	51761	13q12	Hs.444957	4	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process negative regulation of cell proliferation ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
218625_at	0.442	6.380	2.753	1.466e-02	0.395	-2.972	NRN1	neuritin 1	6	-5943231	NM_016588	51299	6p25.1	Hs.103291	7	plasma membrane anchored to membrane
219596_at	0.432	6.128	2.753	1.466e-02	0.395	-2.972	THAP10	THAP domain containing 10	15	-68960734	NM_020147	56906	15q23	Hs.591123	5	DNA binding zinc ion binding metal ion binding
1559688_at	0.452	3.281	2.753	1.466e-02	0.395	-2.972	LOC400581	GRB2-related adaptor protein-like	17	18971506	AK000842	400581	17p11.2	Hs.661470 Hs.677674	1	protein binding
208667_s_at	-0.421	10.144	-2.752	1.468e-02	0.395	-2.973	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22	-39550546	U17714	6767	22q13.2	Hs.712713	29	binding cytoplasm protein folding protein binding, bridging
229287_at	-0.333	7.423	-2.749	1.476e-02	0.397	-2.978	PCNX	pecanex homolog (Drosophila)	14	70443874	BE326214	22990	14q24.2	Hs.446559	10	membrane integral to membrane
205231_s_at	-0.434	8.783	-2.749	1.478e-02	0.397	-2.979	EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	6	-145988132	NM_005670	7957	6q24	Hs.486696	37	protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm endoplasmic reticulum cytosol polysome plasma membrane carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity carbohydrate binding
202303_x_at	-0.403	5.846	-2.749	1.478e-02	0.397	-2.979	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	NM_003601	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
222605_at	0.334	8.633	2.749	1.478e-02	0.397	-2.979	RCOR3	REST corepressor 3	1	209499330, 209499330, 209499911	AI807073	55758	1q32.2	Hs.356399	10	DNA binding protein binding nucleus nucleolus cytoplasm regulation of transcription
221067_s_at	-0.384	5.661	-2.748	1.480e-02	0.397	-2.980	C12orf39	chromosome 12 open reading frame 39	12	21570522	NM_030572	80763	12p12.1	Hs.130692	8	extracellular region nucleus nucleolus secretory granule cytoplasmic vesicle
226519_s_at	0.425	6.955	2.747	1.482e-02	0.397	-2.981	AGXT2L2	alanine-glyoxylate aminotransferase 2-like 2	5	-177568146	AL561859	85007	5q35.3	Hs.248746	4	mitochondrion transaminase activity transferase activity pyridoxal phosphate binding
215748_at	0.269	4.439	2.747	1.483e-02	0.397	-2.982	KLHL35	kelch-like 35 (Drosophila)	11	-74811085	AL050370	283212	11q13.4	Hs.292451	2
225812_at	0.449	6.637	2.747	1.483e-02	0.397	-2.982	C6orf225	chromosome 6 open reading frame 225	6	112515366	N36759	619208	6q21	Hs.591340	1
213361_at	0.323	5.305	2.747	1.484e-02	0.397	-2.983	TDRD7	tudor domain containing 7	9	99214122	AW129593	23424	9q22.33	Hs.193842	8	nucleic acid binding cytoplasm mitochondrial matrix germ cell development ribonucleoprotein complex P granule protein N-terminus binding
204727_at	0.281	2.148	2.746	1.485e-02	0.397	-2.983	WDHD1	WD repeat and HMG-box DNA binding protein 1	14	-54476691	AW772140	11169	14q22.2	Hs.385998	8	DNA binding nucleus nucleoplasm nucleolus cytoplasm
203609_s_at	-0.423	5.278	-2.746	1.487e-02	0.398	-2.985	ALDH5A1	aldehyde dehydrogenase 5 family, member A1	6	24603175	NM_001080	7915	6p22.2-p22.3	Hs.371723	24	succinate-semialdehyde dehydrogenase activity succinate-semialdehyde dehydrogenase activity soluble fraction mitochondrion glucose metabolic process acetate metabolic process succinate metabolic process glutamate metabolic process glutamine metabolic process glycerophospholipid metabolic process galactosylceramide metabolic process glutathione metabolic process central nervous system development gamma-aminobutyric acid catabolic process gamma-aminobutyric acid catabolic process oxidoreductase activity respiratory electron transport chain neurotransmitter catabolic process protein homodimerization activity short-chain fatty acid metabolic process protein homotetramerization oxidation reduction	Alanine, aspartate and glutamate metabolism Butanoate metabolism Metabolic pathways
214037_s_at	-0.293	5.008	-2.744	1.491e-02	0.399	-2.987	CCDC22	coiled-coil domain containing 22	X	48978884	BF224247	28952	Xp11.23	Hs.247700 Hs.26333	6	molecular_function cellular_component biological_process
214657_s_at	-0.455	5.063	-2.743	1.494e-02	0.399	-2.989	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AU134977	283131	11q13.1	Hs.523789 Hs.648467	6
226823_at	0.237	8.078	2.743	1.495e-02	0.399	-2.989	PHACTR4	phosphatase and actin regulator 4	1	28568679, 28637247	AW450293	65979	1p35.3	Hs.225641	7	actin binding phosphoprotein phosphatase inhibitor activity
207616_s_at	-0.454	8.047	-2.742	1.497e-02	0.399	-2.990	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	NM_004180	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
213890_x_at	-0.353	12.550	-2.742	1.499e-02	0.399	-2.992	RPS16	ribosomal protein S16	19	-44615686	AI200589	6217	19q13.1	Hs.397609	24	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
227430_at	-0.244	5.288	-2.742	1.499e-02	0.399	-2.992	ZC3H10	zinc finger CCCH-type containing 10	12	54798296	AI969773	84872	12q13.2	Hs.632706	7	nucleic acid binding zinc ion binding metal ion binding
234952_s_at	-0.297	6.162	-2.742	1.499e-02	0.399	-2.992	PHRF1	PHD and ring finger domains 1	11	566482	BC004950	57661	11p15.5	Hs.325838	8	protein binding zinc ion binding metal ion binding RNA polymerase binding
233893_s_at	0.353	6.677	2.741	1.500e-02	0.399	-2.992	KIAA1530	KIAA1530	4	1331103	AB040963	57654	4p16.3	Hs.380475	3
212967_x_at	-0.333	9.824	-2.741	1.501e-02	0.399	-2.993	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AW148801	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
208335_s_at	0.500	5.922	2.740	1.504e-02	0.400	-2.995	DARC	Duffy blood group, chemokine receptor	1	157441133, 157441824	NM_002036	2532	1q21-q22	Hs.153381	65	G-protein coupled receptor activity chemokine receptor activity plasma membrane defense response signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
52255_s_at	0.284	6.219	2.739	1.506e-02	0.400	-2.996	COL5A3	collagen, type V, alpha 3	19	-9931236	AI984221	50509	19p13.2	Hs.235368	12	extracellular matrix structural constituent collagen binding extracellular region collagen collagen type V cell adhesion cell-matrix adhesion heparin binding collagen fibril organization skin development	Focal adhesion ECM-receptor interaction
212184_s_at	-0.496	7.951	-2.739	1.508e-02	0.400	-2.997	MAP3K7IP2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	6	149680755	AL117407	23118	6q25.1-q25.3	Hs.269775	39	protein binding intracellular cytoplasm cytosol cytosol zinc ion binding membrane positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway Toll-like receptor signaling pathway
1552678_a_at	-0.583	6.183	-2.739	1.508e-02	0.400	-2.997	USP28	ubiquitin specific peptidase 28	11	-113173806	NM_020886	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
243610_at	-1.881	5.491	-2.739	1.509e-02	0.400	-2.997	C9orf135	chromosome 9 open reading frame 135	9	71625550	AI768674	138255	9q21.12	Hs.444459	3	membrane integral to membrane
1559114_a_at	0.192	3.878	2.738	1.510e-02	0.400	-2.998	CXCR7	chemokine (C-X-C motif) receptor 7	2	237143118	BC038720	57007	2q37.3	Hs.471751	21	receptor activity G-protein coupled receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane interspecies interaction between organisms
203581_at	-0.309	8.186	-2.738	1.510e-02	0.400	-2.998	RAB4A	RAB4A, member RAS oncogene family	1	227473501	BC002438	5867	1q42-q43	Hs.296169	43	nucleotide binding GTPase activity GTP binding cytoplasm small GTPase mediated signal transduction protein transport membrane	Endocytosis
204566_at	-0.408	5.770	-2.738	1.511e-02	0.400	-2.999	PPM1D	protein phosphatase 1D magnesium-dependent, delta isoform	17	56032335	NM_003620	8493	17q23.2	Hs.591184	37	magnesium ion binding protein serine/threonine phosphatase activity protein binding nucleus protein amino acid dephosphorylation cell cycle negative regulation of cell proliferation protein serine/threonine phosphatase complex response to radiation hydrolase activity manganese ion binding	p53 signaling pathway
217987_at	-0.405	8.972	-2.737	1.513e-02	0.400	-3.000	ASNSD1	asparagine synthetase domain containing 1	2	190234369	NM_019048	54529	2p24.3-q21.3	Hs.101364	3	asparagine synthase (glutamine-hydrolyzing) activity asparagine biosynthetic process glutamine metabolic process cellular amino acid biosynthetic process
228845_at	0.214	6.076	2.737	1.514e-02	0.400	-3.000	PLBD2	phospholipase B domain containing 2	12	112280753	AW451356	196463	12q24.13	Hs.115896	4	lipid catabolic process hydrolase activity lysosomal lumen
218883_s_at	0.481	3.896	2.737	1.514e-02	0.400	-3.001	MLF1IP	MLF1 interacting protein	4	-185852213	NM_024629	79682	4q35.1	Hs.575032	16	condensed chromosome kinetochore protein binding nucleus chromosome cytoplasm interspecies interaction between organisms regulation of transcription
218631_at	0.300	5.876	2.737	1.515e-02	0.400	-3.001	AVPI1	arginine vasopressin-induced 1	10	-99427170	NM_021732	60370	10q24.2	Hs.23918	9	cell cycle
213939_s_at	0.473	7.138	2.735	1.518e-02	0.400	-3.003	RUFY3	RUN and FYVE domain containing 3	4	71789517, 71806559, 71806559	AI871641	22902	4q13.3	Hs.713172	8	multicellular organismal development nervous system development cell differentiation filopodium growth cone negative regulation of axonogenesis
1554487_a_at	0.431	4.400	2.734	1.522e-02	0.401	-3.005	ATF6B	activating transcription factor 6 beta	6	-32191022, -3490215	BC008394	1388	6p21.3	Hs.42853	15	transcription factor activity intracellular nucleus endoplasmic reticulum regulation of transcription, DNA-dependent response to unfolded protein signal transduction membrane integral to membrane sequence-specific DNA binding protein dimerization activity
242287_at	-0.523	6.343	-2.734	1.522e-02	0.401	-3.005	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	AI090487	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
204151_x_at	1.088	9.982	2.733	1.525e-02	0.402	-3.007	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	10	4995453	NM_001353	1645	10p15-p14	Hs.460260	37	aldo-keto reductase activity cytoplasm cytosol xenobiotic metabolic process digestion bile acid metabolic process bile acid and bile salt transport oxidoreductase activity intestinal cholesterol absorption carboxylic acid binding bile acid binding cholesterol homeostasis response to organophosphorus 20-alpha-hydroxysteroid dehydrogenase activity 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity indanol dehydrogenase activity protein homooligomerization oxidation reduction	Metabolism of xenobiotics by cytochrome P450
214846_s_at	-0.561	7.757	-2.733	1.526e-02	0.402	-3.008	ALPK3	alpha-kinase 3	15	83160914	AB037751	57538	15q25.2	Hs.459183	5	protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation multicellular organismal development heart development kinase activity transferase activity
206121_at	-0.798	10.853	-2.732	1.528e-02	0.402	-3.009	AMPD1	adenosine monophosphate deaminase 1 (isoform M)	1	-115017244	NM_000036	270	1p13	Hs.89570	59	AMP deaminase activity purine base metabolic process nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process hydrolase activity	Purine metabolism Biosynthesis of plant hormones Metabolic pathways
226060_at	-0.305	4.822	-2.732	1.529e-02	0.402	-3.009	RFT1	RFT1 homolog (S. cerevisiae)	3	-53097542	BF475369	91869	3p21.1	Hs.631910	3	lipid transporter activity lipid transport carbohydrate transport membrane integral to membrane	N-Glycan biosynthesis
203978_at	-0.260	7.047	-2.732	1.529e-02	0.402	-3.009	NUBP1	nucleotide binding protein 1 (MinD homolog, E. coli)	16	10745198	NM_002484	4682	16p13.13	Hs.81469	9	nucleotide binding protein binding ATP binding cytosol cellular iron ion homeostasis cell growth iron-sulfur cluster assembly nucleoside-triphosphatase activity iron-sulfur cluster binding
222717_at	0.468	6.895	2.732	1.530e-02	0.402	-3.010	SDPR	serum deprivation response (phosphatidylserine binding protein)	2	-192407280	BF982174	8436	2q32-q33	Hs.26530	12	phosphatidylserine binding protein binding cytoplasm cytosol caveola membrane
219757_s_at	0.361	4.706	2.731	1.531e-02	0.402	-3.011	C14orf101	chromosome 14 open reading frame 101	14	56116263	NM_017799	54916	14q22.3	Hs.497253	3	membrane integral to membrane
208554_at	-0.216	3.061	-2.730	1.533e-02	0.402	-3.012	POU4F3	POU class 4 homeobox 3	5	145698779	NM_002700	5459	5q31	Hs.553499	12	transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter visual perception sensory perception of sound vestibulocochlear nerve development retinal ganglion cell axon guidance inner ear morphogenesis auditory receptor cell differentiation sequence-specific DNA binding axon extension involved in development neuromuscular process controlling balance neuron apoptosis
209487_at	0.314	6.152	2.730	1.534e-02	0.402	-3.012	RBPMS	RNA binding protein with multiple splicing	8	30361485, 30361485	D84109	11030	8p12-p11	Hs.334587	8	nucleotide binding RNA binding protein binding RNA processing
1558327_at	0.303	5.315	2.730	1.535e-02	0.402	-3.013	ZDHHC18	zinc finger, DHHC-type containing 18	1	27025787	AW408061	84243	1p36.11	Hs.523710	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
215242_at	-0.330	4.111	-2.729	1.537e-02	0.402	-3.014	PIGC	phosphatidylinositol glycan anchor biosynthesis, class C	1	-170677219	AL035301	5279	1q23-q25	Hs.188456	12	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring glycosyl groups phosphatidylinositol N-acetylglucosaminyltransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
209577_at	0.214	6.605	2.729	1.537e-02	0.402	-3.014	PCYT2	phosphate cytidylyltransferase 2, ethanolamine	17	-77455383, -2421678	BC000351	5833	17q25.3	Hs.645248	8	ethanolamine-phosphate cytidylyltransferase activity cellular_component phospholipid biosynthetic process biosynthetic process transferase activity nucleotidyltransferase activity	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
228452_at	-0.456	6.951	-2.729	1.538e-02	0.402	-3.015	C17orf39	chromosome 17 open reading frame 39	17	17883335	AA827865	79018	17p11.2	Hs.187422	5
225557_at	-0.873	5.848	-2.729	1.539e-02	0.402	-3.015	CSRNP1	cysteine-serine-rich nuclear protein 1	3	-39158347	AI091372	64651	3p22	Hs.370950	4	molecular_function transcription factor activity cellular_component nucleus apoptosis regulation of transcription positive regulation of transcription from RNA polymerase II promoter
1569368_at	0.281	4.748	2.728	1.540e-02	0.402	-3.016	LOC283693	actin, gamma pseudogene	15		BC014481	283693	15q25.2	Hs.560399	1
209554_at	0.292	5.067	2.728	1.540e-02	0.402	-3.016	CD36	CD36 molecule (thrombospondin receptor)	7	80069439, 80105767, 80105767, 80113580, 80113697	BE968792	948	7q11.2	Hs.120949	173	positive regulation of cell-matrix adhesion low-density lipoprotein receptor activity membrane fraction Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process transport cell adhesion nitric oxide mediated signal transduction blood coagulation high-density lipoprotein binding lipid binding cell surface cell surface positive regulation of foam cell differentiation plasma membrane long-chain fatty acid transport lipid storage cGMP-mediated signaling cholesterol transport platelet alpha granule membrane lipoprotein particle clearance lipoprotein catabolic process lipoprotein transport apoptotic cell clearance transforming growth factor beta binding thrombospondin receptor activity	PPAR signaling pathway ECM-receptor interaction Hematopoietic cell lineage Adipocytokine signaling pathway
236841_at	0.517	5.562	2.727	1.543e-02	0.402	-3.017	WASH3P	WAS protein family homolog 3 pseudogene	15	100318538	BE464132	374666	15q26.3	Hs.459573 Hs.585931	6
202501_at	-0.504	7.499	-2.727	1.545e-02	0.402	-3.019	MAPRE2	microtubule-associated protein, RP/EB family, member 2	18	30810889, 30812205, 30875321	NM_014268	10982	18q12.1-q12.2	Hs.532824	27	cytoplasm microtubule cell cycle mitosis signal transduction microtubule binding cell proliferation cell division
225770_at	0.258	7.067	2.727	1.545e-02	0.402	-3.019	RSPRY1	ring finger and SPRY domain containing 1	16	55777741	AI206557	89970	16q13	Hs.460885	5	protein binding extracellular region zinc ion binding metal ion binding
232349_x_at	-0.453	9.489	-2.726	1.546e-02	0.402	-3.019	DCAF6	DDB1 and CUL4 associated factor 6	1	166172531	BF671187	55827	1q24.2	Hs.435741	10	nucleus ligand-dependent nuclear receptor transcription coactivator activity
241383_at	0.318	4.344	2.726	1.547e-02	0.402	-3.019	ZNF385C	zinc finger protein 385C	17		H05959	201181	17q21.2	Hs.443140	2	nucleic acid binding intracellular nucleus zinc ion binding metal ion binding
224605_at	-0.435	8.095	-2.726	1.547e-02	0.402	-3.019	C4orf3	chromosome 4 open reading frame 3	4	-120437021	AV727336	401152	4q26	Hs.701808 Hs.718451	5	membrane integral to membrane
224364_s_at	0.801	7.632	2.725	1.550e-02	0.403	-3.021	PPIL3	peptidylprolyl isomerase (cyclophilin)-like 3	2	-201443924, -201443923, -201443923	AF251049	53938	2q33.1	Hs.121076	11	peptidyl-prolyl cis-trans isomerase activity protein binding spliceosomal complex mRNA processing protein folding RNA splicing isomerase activity
238231_at	0.465	4.503	2.724	1.553e-02	0.403	-3.023	NFYC	nuclear transcription factor Y, gamma	1	40929828, 40930266	AV700263	4802	1p32	Hs.233458 Hs.713051	24	transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding intracellular nucleus regulation of transcription from RNA polymerase II promoter protein folding CCAAT-binding factor complex sequence-specific DNA binding	Antigen processing and presentation
1563874_at	-0.277	4.068	-2.724	1.553e-02	0.403	-3.023	WDR72	WD repeat domain 72	15	-51593229	AK096055	256764	15q21.3	Hs.122125	4
223039_at	-0.373	9.036	-2.723	1.556e-02	0.403	-3.025	C22orf13	chromosome 22 open reading frame 13	22	-23266407	BC004144	83606	22q11.2	Hs.9850	3
204221_x_at	0.277	3.961	2.723	1.556e-02	0.403	-3.025	GLIPR1	GLI pathogenesis-related 1	12	74160779	U16307	11010	12q21.2	Hs.205558	13	extracellular region membrane integral to membrane
201928_at	0.216	6.967	2.722	1.559e-02	0.403	-3.027	PKP4	plakophilin 4	2	159021721	AA194254	8502	2q23-q31	Hs.407580	27	protein binding cell adhesion desmosome
220819_at	0.180	5.801	2.722	1.560e-02	0.403	-3.027	FRMD1	FERM domain containing 1	6	-168199312, -168199312	NM_024919	79981	6q27	Hs.266746	2	binding cytoskeleton
211578_s_at	-0.328	4.928	-2.722	1.560e-02	0.403	-3.027	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	M60725	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
230000_at	-0.353	4.654	-2.722	1.560e-02	0.403	-3.027	RNF213	ring finger protein 213	17	75928320	AI523817	57674	17q25.3	Hs.195642 Hs.657519	6	nucleotide binding protein binding zinc ion binding nucleoside-triphosphatase activity metal ion binding
236320_at	0.265	3.883	2.720	1.566e-02	0.403	-3.030	CCDC17	coiled-coil domain containing 17	1	-45858302	AA010540	149483	1p34.1	Hs.18912	3
235475_at	0.386	6.018	2.720	1.566e-02	0.403	-3.030	SERP1	stress-associated endoplasmic reticulum protein 1	3	-151742469	AI580135	27230	3q25.1	Hs.518326 Hs.709270	10	skeletal system development endoplasmic reticulum ribosome glucose metabolic process protein amino acid glycosylation response to stress plasma membrane organization post-embryonic development multicellular organismal aging protein transport membrane integral to membrane endoplasmic reticulum unfolded protein response positive regulation of insulin secretion positive regulation of translation positive regulation of organ growth muscle organ morphogenesis positive regulation of growth hormone secretion intracellular protein transmembrane transport
205348_s_at	0.464	5.722	2.720	1.566e-02	0.403	-3.030	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	7	95239753	NM_004411	1780	7q21.3-q22.1	Hs.440364	17	microtubule motor activity protein binding cytoplasmic dynein complex microtubule microtubule binding vesicle transport along microtubule perinuclear region of cytoplasm
212155_at	0.615	8.699	2.720	1.566e-02	0.403	-3.030	RNF187	ring finger protein 187	1	226741716	AA085748	149603	1q42.13	Hs.356377 Hs.679030	3
205395_s_at	-0.292	5.026	-2.720	1.566e-02	0.403	-3.031	MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	11	-93790114	NM_005590	4361	11q21	Hs.192649	107	single-stranded DNA specific endodeoxyribonuclease activity regulation of mitotic recombination DNA binding double-stranded DNA binding nucleus nucleoplasm nucleolus double-strand break repair via nonhomologous end joining response to DNA damage stimulus telomere maintenance via telomerase meiosis reciprocal meiotic recombination protein C-terminus binding 3'-5' exonuclease activity hydrolase activity manganese ion binding	Homologous recombination Non-homologous end-joining
1557523_at	0.352	3.764	2.720	1.567e-02	0.403	-3.031	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	5	81636921	AW269750	92270	5q14.2	Hs.364045	2	ATP synthesis coupled proton transport membrane integral to membrane proton-transporting V-type ATPase, V1 domain hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism
207397_s_at	0.230	3.123	2.719	1.569e-02	0.403	-3.032	HOXD13	homeobox D13	2	176665777	NM_000523	3239	2q31.1	Hs.152414	37	skeletal system development transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter multicellular organismal development sequence-specific DNA binding
208617_s_at	-0.537	10.462	-2.719	1.570e-02	0.403	-3.033	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	AF208850	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
220992_s_at	-0.473	7.704	-2.718	1.571e-02	0.403	-3.033	C1orf25	chromosome 1 open reading frame 25	1	-183353840	NM_030934	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
228693_at	0.453	6.246	2.718	1.573e-02	0.403	-3.034	CCDC50	coiled-coil domain containing 50	3	192529567	AI681307	152137	3q28	Hs.478682	12	protein binding cytoplasm
1557918_s_at	-0.250	5.117	-2.718	1.573e-02	0.403	-3.034	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	AU131482	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
220920_at	-0.336	5.211	-2.718	1.573e-02	0.403	-3.035	ATP10B	ATPase, class V, type 10B	5	-159922704	NM_025153	23120	5q34	Hs.109358	5	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
225333_at	0.255	4.335	2.717	1.574e-02	0.403	-3.035	ZNF496	zinc finger protein 496	1	-245530244	AI218383	84838	1q44	Hs.654803	5	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201594_s_at	0.223	7.518	2.717	1.574e-02	0.403	-3.035	PPP4R1	protein phosphatase 4, regulatory subunit 1	18	-9536791	NM_005134	9989	18p11.22	Hs.719096	11	protein binding soluble fraction signal transduction protein phosphatase type 4 regulator activity
209480_at	0.999	4.013	2.717	1.574e-02	0.403	-3.035	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M16276	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
210957_s_at	-0.298	3.676	-2.717	1.575e-02	0.403	-3.035	AFF2	AF4/FMR2 family, member 2	X	147389830	L76569	2334	Xq28	Hs.496911	21	protein binding brain development
242956_at	0.264	3.682	2.717	1.575e-02	0.403	-3.036	IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	2	-208809197	AA564352	3417	2q33.3	Hs.593422 Hs.714620	33	magnesium ion binding isocitrate dehydrogenase (NADP+) activity cytoplasm peroxisome cytosol carbohydrate metabolic process glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process glutathione metabolic process response to oxidative stress oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Glutathione metabolism Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
200686_s_at	0.332	9.568	2.716	1.577e-02	0.403	-3.037	SFRS11	splicing factor, arginine/serine-rich 11	1	70443952	NM_004768	9295	1p31	Hs.479693	13	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleolus RNA splicing
230122_at	0.317	3.275	2.716	1.578e-02	0.403	-3.037	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10	21863107, 21863579	BE219716	8028	10p12	Hs.30385	19	transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding
204248_at	-0.296	8.246	-2.716	1.578e-02	0.403	-3.037	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	19	3045407	NM_002067	2767	19p13.3	Hs.650575 Hs.654784	44	nucleotide binding skeletal system development regulation of action potential GTPase activity signal transducer activity GTP binding cytoplasm plasma membrane protein amino acid ADP-ribosylation signal transduction G-protein coupled receptor protein signaling pathway heart development guanyl nucleotide binding regulation of melanocyte differentiation pigmentation during development activation of phospholipase C activity by dopamine receptor signaling pathway	Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term depression GnRH signaling pathway
216239_at	0.233	2.933	2.716	1.578e-02	0.403	-3.037	BBS9	Bardet-Biedl syndrome 9	7	33135676	U87408	27241	7p14	Hs.372360	9	molecular_function cytoplasm centrosome plasma membrane cilium visual perception BBSome fat cell differentiation response to stimulus cilium membrane
203543_s_at	-0.815	7.801	-2.716	1.579e-02	0.403	-3.038	KLF9	Kruppel-like factor 9	9	-72189332	NM_001206	687	9q13	Hs.150557 Hs.602267	19	transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter embryo implantation zinc ion binding regulation of transcription metal ion binding progesterone receptor signaling pathway
202734_at	-0.354	7.090	-2.715	1.581e-02	0.403	-3.039	TRIP10	thyroid hormone receptor interactor 10	19	6690706	NM_004240	9322	19p13.3	Hs.515094	28	cytoplasm lysosome Golgi apparatus cytoskeleton plasma membrane cell cortex endocytosis signal transduction lipid binding actin cytoskeleton organization identical protein binding perinuclear region of cytoplasm	Insulin signaling pathway
213638_at	0.214	2.696	2.715	1.582e-02	0.403	-3.040	PHACTR1	phosphatase and actin regulator 1	6	12825818	AW054711	221692	6p24.1	Hs.436996	8	actin binding phosphoprotein phosphatase inhibitor activity cytoplasm cell junction synapse
202379_s_at	0.344	7.803	2.715	1.583e-02	0.404	-3.040	NKTR	natural killer-tumor recognition sequence	3	42617150	AI361805	4820	3p23-p21	Hs.529509	9	peptidyl-prolyl cis-trans isomerase activity protein folding cyclosporin A binding membrane isomerase activity
206453_s_at	-0.437	11.058	-2.714	1.585e-02	0.404	-3.041	NDRG2	NDRG family member 2	14	-20554761, -20554761	NM_016250	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
201464_x_at	-0.416	9.248	-2.714	1.585e-02	0.404	-3.041	JUN	jun oncogene	1	-59019050	BG491844	3725	1p32-p31	Hs.714791	443	nuclear chromosome transcription factor activity RNA polymerase II transcription factor activity Rho GTPase activator activity nucleus transcription factor complex cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation transcription factor binding negative regulation of cell proliferation cellular process promoter binding negative regulation of protein amino acid autophosphorylation leading edge cell differentiation response to drug positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein dimerization activity regulation of cell cycle SMAD protein signal transduction R-SMAD binding	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma
1561923_a_at	-0.247	3.630	-2.712	1.590e-02	0.405	-3.044	SF3B14	splicing factor 3B, 14 kDa subunit	2	-24143957	AF147425	51639	2pter-p25.1	Hs.177861	14	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus RNA splicing
238653_at	0.301	6.641	2.712	1.590e-02	0.405	-3.044	LRIG2	leucine-rich repeats and immunoglobulin-like domains 2	1	113417353	BF967997	9860	1p13.1	Hs.448972 Hs.696605	7	protein binding cytoplasm plasma membrane integral to membrane
242114_at	-0.406	5.000	-2.712	1.591e-02	0.405	-3.044	BOLA2	bolA homolog 2 (E. coli)	16	-30111756, -29372414	BF088991	552900	16p11.2	Hs.444600 Hs.655267	5
204927_at	0.173	6.532	2.711	1.594e-02	0.405	-3.046	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	11	550970, 551449	NM_003475	8045	11p15.5	Hs.72925	9	DNA binding protein binding nucleus regulation of transcription, DNA-dependent signal transduction
222436_s_at	-0.225	8.492	-2.711	1.594e-02	0.405	-3.046	VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	2	-86584063	AF219226	51652	2p24.3-p24.1	Hs.591582	25	protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division	Endocytosis
204344_s_at	-0.544	6.373	-2.711	1.595e-02	0.405	-3.047	SEC23A	Sec23 homolog A (S. cerevisiae)	14	-38570873	NM_006364	10484	14q21.1	Hs.272927	18	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport zinc ion binding membrane membrane organization vesicle-mediated transport COPII vesicle coat perinuclear region of cytoplasm
203091_at	-0.210	6.796	-2.710	1.598e-02	0.405	-3.048	FUBP1	far upstream element (FUSE) binding protein 1	1	-78186178	NM_003902	8880	1p31.1	Hs.567380	28	single-stranded DNA binding transcription factor activity RNA binding protein binding nucleus nucleolus transcription from RNA polymerase II promoter regulation of transcription
218401_s_at	-0.501	6.409	-2.710	1.599e-02	0.405	-3.049	ZNF281	zinc finger protein 281	1	-198642042	NM_012482	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
202354_s_at	0.236	5.134	2.709	1.601e-02	0.405	-3.050	GTF2F1	general transcription factor IIF, polypeptide 1, 74kDa	19	-6330579	AW190445	2962	19p13.3	Hs.68257	79	nuclear mRNA splicing, via spliceosome DNA binding transcription coactivator activity catalytic activity nucleus nucleoplasm transcription factor TFIIF complex transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter transcription factor binding general RNA polymerase II transcription factor activity positive regulation of transcription	Basal transcription factors
202418_at	0.316	8.675	2.709	1.601e-02	0.405	-3.050	YIF1A	Yip1 interacting factor homolog A (S. cerevisiae)	11	-65808626	NM_020470	10897	11q13	Hs.446445	13	cytoplasm endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus protein transport membrane integral to membrane vesicle-mediated transport
1553755_at	0.224	6.570	2.709	1.603e-02	0.405	-3.051	NXNL1	nucleoredoxin-like 1	19	-17427233	NM_138454	115861	19p13.11	Hs.661836	6	nucleus nuclear outer membrane mitochondrion membrane cell redox homeostasis
221555_x_at	0.333	6.241	2.708	1.604e-02	0.406	-3.052	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	9	-98302215, -98302215	AU145941	8555	9q22.32-q22.33	Hs.40582	17	protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus nucleolus protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity	Cell cycle
1553351_at	0.314	3.749	2.707	1.607e-02	0.406	-3.054	OTUD7A	OTU domain containing 7A	15	-29562620	NM_130901	161725	15q13.3	Hs.355236	2	DNA binding nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process metal ion binding
226310_at	-0.461	5.876	-2.707	1.608e-02	0.406	-3.054	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	AI743511	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
225904_at	-0.442	5.579	-2.706	1.610e-02	0.406	-3.055	C1orf96	chromosome 1 open reading frame 96	1	-227523374	N64686	126731	1q42.13	Hs.715507	2
232119_at	-0.584	7.352	-2.705	1.614e-02	0.407	-3.057	SYNPO2	synaptopodin 2	4	120029443, 120029443	BF984227	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
219448_at	-1.212	7.532	-2.704	1.616e-02	0.407	-3.058	TMEM70	transmembrane protein 70	8	75050983	BC002748	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
219236_at	0.298	5.607	2.704	1.617e-02	0.408	-3.059	PAQR6	progestin and adipoQ receptor family member VI	1	-154479833, -154479830	NM_024897	79957	1q22	Hs.235873	5	receptor activity membrane integral to membrane
204795_at	0.275	5.049	2.703	1.620e-02	0.408	-3.061	PRR3	proline rich 3	6	30632734, 1973311, 1771606	NM_025263	80742	6p21.33	Hs.118354 Hs.651434 Hs.83147	4	nucleic acid binding zinc ion binding metal ion binding
204560_at	-0.576	4.975	-2.703	1.620e-02	0.408	-3.061	FKBP5	FK506 binding protein 5	6	-35656311, -35649339, -35649339, -35649339	NM_004117	2289	6p21.3-p21.2	Hs.407190	50	peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding
228570_at	0.391	4.354	2.703	1.621e-02	0.408	-3.061	BTBD11	BTB (POZ) domain containing 11	12	106236326, 106498763	BF510581	121551	12q23.3	Hs.271272	2	DNA binding protein binding membrane integral to membrane
223700_at	-0.233	2.708	-2.703	1.621e-02	0.408	-3.061	MND1	meiotic nuclear divisions 1 homolog (S. cerevisiae)	4	154485250	AY028916	84057	4q31.3	Hs.294088	4	DNA binding protein binding nucleus DNA recombination meiosis
32128_at	0.303	3.617	2.703	1.622e-02	0.408	-3.061	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	17	31415755	Y13710	6362	17q11.2	Hs.143961	35	extracellular region extracellular space chemotaxis inflammatory response immune response signal transduction cell-cell signaling chemokine activity response to biotic stimulus	Cytokine-cytokine receptor interaction Chemokine signaling pathway
202381_at	-0.345	7.704	-2.702	1.625e-02	0.408	-3.063	ADAM9	ADAM metallopeptidase domain 9 (meltrin gamma)	8	38973661, 38973661	NM_003816	8754	8p11.22	Hs.591852	36	activation of MAPKK activity metalloendopeptidase activity protein kinase C binding integrin binding integrin binding integrin binding collagen binding extracellular region extracellular space cytoplasm plasma membrane proteolysis response to oxidative stress cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway peptidase activity zinc ion binding cell surface response to manganese ion integral to membrane SH3 domain binding SH3 domain binding keratinocyte differentiation intrinsic to external side of plasma membrane positive regulation of cell adhesion mediated by integrin cell-cell adhesion mediated by integrin positive regulation of macrophage fusion response to tumor necrosis factor monocyte activation response to hydrogen peroxide laminin binding metal ion binding positive regulation of protein secretion positive regulation of membrane protein ectodomain proteolysis PMA-inducible membrane protein ectodomain proteolysis response to glucocorticoid stimulus positive regulation of keratinocyte migration response to calcium ion
203811_s_at	-1.038	7.287	-2.702	1.625e-02	0.408	-3.063	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1	78243223	NM_007034	11080	1p31.1	Hs.13852	11	protein folding response to unfolded protein response to heat heat shock protein binding unfolded protein binding
243709_at	0.470	4.080	2.701	1.629e-02	0.409	-3.065	SLC38A9	solute carrier family 38, member 9	5	-54957432	BG054799	153129	5q11.2	Hs.649685	3	ion transport sodium ion transport amino acid transport membrane integral to membrane sodium ion binding
212992_at	0.297	3.712	2.700	1.631e-02	0.409	-3.066	AHNAK2	AHNAK nucleoprotein 2	14	-104474635	AI935123	113146	14q32.33	Hs.441783	3	protein binding nucleus cytoplasm keratinization
203065_s_at	0.524	9.957	2.699	1.634e-02	0.409	-3.068	CAV1	caveolin 1, caveolae protein, 22kDa	7	115952074	NM_001753	857	7q31.1	Hs.74034	318	Golgi membrane Golgi membrane inactivation of MAPK activity vasculogenesis response to hypoxia negative regulation of endothelial cell proliferation intracellular endoplasmic reticulum Golgi apparatus lipid particle plasma membrane caveola triglyceride metabolic process calcium ion transport endocytosis regulation of smooth muscle contraction skeletal muscle tissue development protein localization positive regulation of calcium ion transport into cytosol cholesterol binding integral to membrane vesicle organization peptidase activator activity regulation of fatty acid metabolic process lipid storage regulation of blood coagulation cholesterol transport negative regulation of epithelial cell differentiation mammary gland development maintenance of protein location in cell response to progesterone stimulus protein complex scaffold nitric oxide homeostasis cholesterol homeostasis negative regulation of MAPKKK cascade response to estrogen stimulus interspecies interaction between organisms negative regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction negative regulation of vasodilation negative regulation of JAK-STAT cascade perinuclear region of cytoplasm positive regulation of metalloenzyme activity nitric-oxide synthase binding protein homooligomerization cytosolic calcium ion homeostasis response to calcium ion membrane depolarization regulation of peptidase activity mammary gland involution	Focal adhesion
225701_at	0.297	5.259	2.699	1.635e-02	0.409	-3.069	AKNA	AT-hook transcription factor	9	-116136254	AK024431	80709	9q32	Hs.494895	5	DNA binding nucleus regulation of transcription
225985_at	0.214	4.297	2.698	1.638e-02	0.409	-3.070	PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	5	-40795237	AI935917	5562	5p12	Hs.43322	68	nucleotide binding activation of MAPK activity magnesium ion binding response to hypoxia protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein binding ATP binding intracellular glucose metabolic process fatty acid biosynthetic process signal transduction transferase activity fatty acid oxidation positive regulation of cholesterol biosynthetic process positive regulation of anti-apoptosis negative regulation of glucosylceramide biosynthetic process	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
212515_s_at	-0.630	8.010	-2.698	1.638e-02	0.409	-3.070	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	X	41077594	BG492602	1654	Xp11.3-p11.23	Hs.719127	34	nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus cytoplasm plasma membrane nuclear speck hydrolase activity interspecies interaction between organisms	RIG-I-like receptor signaling pathway
202704_at	-0.463	10.582	-2.697	1.639e-02	0.409	-3.071	TOB1	transducer of ERBB2, 1	17	-46294585	AA675892	10140	17q21	Hs.709952 Hs.714409 Hs.719207	29	transcription corepressor activity SH3/SH2 adaptor activity cytoplasm SMAD protein nuclear translocation negative regulation of cell proliferation negative regulation of BMP signaling pathway negative regulation of osteoblast differentiation SMAD binding
224642_at	-0.739	7.117	-2.697	1.640e-02	0.409	-3.071	FYTTD1	forty-two-three domain containing 1	3	198960820, 198961020, 198961657	BG291550	84248	3q29	Hs.277533	6
1569701_at	-0.591	3.757	-2.697	1.640e-02	0.409	-3.071	PER3	period homolog 3 (Drosophila)	1	7767349	BC036937	8863	1p36.23	Hs.162200	35	signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction rhythmic process	Circadian rhythm - mammal
1554077_a_at	0.317	5.760	2.697	1.642e-02	0.409	-3.072	TMEM53	transmembrane protein 53	1	-44892087	BC007521	79639	1p34.1	Hs.22157	5	Golgi apparatus plasma membrane focal adhesion integral to membrane
218285_s_at	0.225	8.077	2.697	1.642e-02	0.409	-3.072	BDH2	3-hydroxybutyrate dehydrogenase, type 2	4	-104218230	NM_020139	56898	4q24	Hs.124696	7	3-hydroxybutyrate dehydrogenase activity binding cytoplasm mitochondrion fatty acid beta-oxidation oxidoreductase activity NAD or NADH binding oxidation reduction	Synthesis and degradation of ketone bodies Butanoate metabolism Metabolic pathways
1557119_a_at	0.302	5.833	2.696	1.644e-02	0.409	-3.073	ZNF575	zinc finger protein 575	19	48729179	AK057129	284346	19q13.31	Hs.213534	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
209678_s_at	0.349	6.378	2.696	1.645e-02	0.409	-3.074	PRKCI	protein kinase C, iota	3	171422913	L18964	5584	3q26.3	Hs.478199	91	polarisome nucleotide binding protein kinase C activity protein binding ATP binding phospholipid binding nucleus cytoplasm endosome cytosol protein amino acid phosphorylation protein targeting to membrane cytoskeleton organization actin filament organization intracellular signaling cascade zinc ion binding membrane membrane organization vesicle-mediated transport apical plasma membrane transferase activity diacylglycerol binding cellular response to insulin stimulus establishment of apical/basal cell polarity eye photoreceptor cell development establishment or maintenance of epithelial cell apical/basal polarity cell-cell junction organization positive regulation of glucose import metal ion binding secretion Golgi vesicle budding regulation of establishment of protein localization	Endocytosis Tight junction Insulin signaling pathway
241813_at	-0.547	5.183	-2.695	1.648e-02	0.409	-3.075	MBD1	methyl-CpG binding domain protein 1	18	-46049213	BG252318	4152	18q21	Hs.405610	40	transcription factor activity transcription corepressor activity protein binding nucleus transcription from RNA polymerase II promoter zinc ion binding methyl-CpG binding negative regulation of transcription nuclear speck metal ion binding
1552470_a_at	0.370	5.231	2.695	1.648e-02	0.409	-3.076	ABHD11	abhydrolase domain containing 11	7	-72789980, -72789935, -72788362, -72788362	NM_148914	83451	7q11.23	Hs.647045	9	molecular_function cellular_component biological_process hydrolase activity
204526_s_at	-0.553	8.010	-2.694	1.649e-02	0.409	-3.076	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)	2	-100990121	NM_007063	11138	2q11.2	Hs.442657	8	GTPase activator activity Rab GTPase activator activity intracellular blood circulation positive regulation of cell proliferation membrane regulation of Rab GTPase activity
204263_s_at	0.425	6.825	2.694	1.649e-02	0.409	-3.076	CPT2	carnitine palmitoyltransferase 2	1	53434688	M58581	1376	1p32	Hs.713535	53	carnitine O-palmitoyltransferase activity carnitine O-palmitoyltransferase activity mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport carnitine shuttle acyltransferase activity membrane transferase activity regulation of fatty acid oxidation	Fatty acid metabolism PPAR signaling pathway
233193_x_at	0.224	6.327	2.694	1.652e-02	0.410	-3.078	INTS4	integrator complex subunit 4	11	-77267413	AK000455	92105	11q14.1	Hs.533723	3	protein binding nucleus snRNA processing integrator complex
230071_at	0.309	4.856	2.693	1.653e-02	0.410	-3.078	SEPT11	septin 11	4	78089918	AI333326	55752	4q21.1	Hs.128199	16	nucleotide binding stress fiber protein binding GTP binding cell cycle septin complex protein heterooligomerization cell division
1556436_at	0.297	3.392	2.693	1.654e-02	0.410	-3.079	C8orf50	chromosome 8 open reading frame 50	8		BC043205	340414	8p21.1	Hs.667366	1
205181_at	0.319	6.308	2.693	1.655e-02	0.410	-3.079	ZNF193	zinc finger protein 193	6	28301051	NM_006299	7746	6p21.3	Hs.100921	8	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212161_at	0.232	4.624	2.692	1.658e-02	0.410	-3.081	AP2A2	adaptor-related protein complex 2, alpha 2 subunit	11	915840	AA994666	161	11p15.5	Hs.19121	41	protein binding cytosol plasma membrane plasma membrane coated pit intracellular protein transport endocytosis lipid binding protein transporter activity membrane coat AP-2 adaptor complex regulation of defense response to virus by virus	Endocytosis Huntington's disease
208715_at	-0.218	7.162	-2.691	1.659e-02	0.410	-3.082	TMCO1	transmembrane and coiled-coil domains 1	1	-163960151	BF002031	54499	1q22-q25	Hs.31498 Hs.715707	12	endoplasmic reticulum Golgi apparatus membrane integral to membrane
225726_s_at	0.655	5.398	2.691	1.660e-02	0.410	-3.082	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	14	67069760	AB033026	57475	14q24.1	Hs.594236	4	binding cytoskeleton
227970_at	-0.467	8.917	-2.691	1.660e-02	0.410	-3.082	GPR157	G protein-coupled receptor 157	1	-9087062	AK026883	80045	1p36.23	Hs.632367	5	G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane
243452_at	0.377	3.711	2.690	1.663e-02	0.411	-3.084	LOC646778	hypothetical LOC646778	18		BE895304	646778	18q12.1	Hs.631680	1
227711_at	1.045	3.836	2.690	1.664e-02	0.411	-3.084	GTSF1	gametocyte specific factor 1	12	-53136002	BG150433	121355	12q13.13	Hs.524476	3	cytoplasm zinc ion binding metal ion binding
230442_at	0.356	3.783	2.689	1.666e-02	0.411	-3.085	MTHFSD	methenyltetrahydrofolate synthetase domain containing	16	-85121283, -85121283, -85121282	AI700675	64779	16q24.1	Hs.343627	2	nucleotide binding RNA binding ATP binding folic acid and derivative biosynthetic process 5-formyltetrahydrofolate cyclo-ligase activity
209939_x_at	0.541	8.223	2.689	1.667e-02	0.411	-3.086	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	AF005775	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
1559584_a_at	0.293	2.523	2.688	1.670e-02	0.411	-3.087	C16orf54	chromosome 16 open reading frame 54	16	-29661286, -41077	BC025741	283897	16p11.2	Hs.331095	7	membrane integral to membrane
222673_x_at	0.496	5.100	2.688	1.670e-02	0.411	-3.087	FAM122B	family with sequence similarity 122B	X	-133731261	AI582192	159090	Xq26.3	Hs.404706	10
204450_x_at	-0.310	4.026	-2.688	1.672e-02	0.411	-3.088	APOA1	apolipoprotein A-I	11	-116211678, 13497	NM_000039	335	11q23-q24	Hs.633003	424	beta-amyloid binding negative regulation of cytokine secretion during immune response phospholipid binding extracellular region extracellular region endoplasmic reticulum lumen lipid metabolic process phosphatidylcholine biosynthetic process lipid transport G-protein coupled receptor protein signaling pathway steroid metabolic process cholesterol metabolic process positive regulation of cholesterol esterification negative regulation of very-low-density lipoprotein particle remodeling cholesterol binding cholesterol transporter activity cholesterol transporter activity enzyme binding endocytic vesicle cytoplasmic vesicle Cdc42 protein signal transduction cholesterol efflux phospholipid efflux apolipoprotein A-I receptor binding very-low-density lipoprotein particle spherical high-density lipoprotein particle high-density lipoprotein particle assembly high-density lipoprotein particle clearance lipoprotein metabolic process cholesterol homeostasis identical protein binding reverse cholesterol transport negative regulation of interleukin-1 beta secretion protein stabilization positive regulation of hydrolase activity phosphatidylcholine-sterol O-acyltransferase activator activity cholesterol import high-density lipoprotein receptor binding	PPAR signaling pathway
200733_s_at	-0.362	10.246	-2.687	1.675e-02	0.411	-3.090	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	U48296	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
226210_s_at	-1.083	5.071	-2.687	1.675e-02	0.411	-3.090	MEG3	maternally expressed 3 (non-protein coding)	14	100362197, 100362215	AI291123	55384	14q32	Hs.525589 Hs.593706 Hs.654863 Hs.655127	11
214246_x_at	0.319	7.489	2.687	1.675e-02	0.411	-3.090	MINK1	misshapen-like kinase 1 (zebrafish)	17	4683350	AI859060	50488	17p13.2	Hs.443417	16	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade multicellular organismal development transferase activity
218193_s_at	-0.436	5.717	-2.686	1.676e-02	0.411	-3.090	GOLT1B	golgi transport 1 homolog B (S. cerevisiae)	12	21545965	NM_016072	51026	12p12.1	Hs.62275	10	signal transducer activity endoplasmic reticulum Golgi apparatus protein transport membrane integral to membrane vesicle-mediated transport positive regulation of I-kappaB kinase/NF-kappaB cascade
203662_s_at	-0.442	9.137	-2.686	1.676e-02	0.411	-3.090	TMOD1	tropomodulin 1	9	99326257	NM_003275	7111	9q22.3	Hs.494595	18	actin binding tropomyosin binding nucleus cytoplasm membrane myofibril myofibril assembly cortical cytoskeleton
205120_s_at	-0.361	8.075	-2.686	1.677e-02	0.411	-3.091	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	4	-52581617	U29586	6443	4q12	Hs.438953	28	cytoplasm cytoskeleton plasma membrane integral to plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
217077_s_at	-0.335	4.156	-2.686	1.677e-02	0.411	-3.091	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	9	-100090186	AF095723	9568	9q22.1-q22.3	Hs.198612	27	receptor activity G-protein coupled receptor activity GABA-B receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane signal transduction negative regulation of adenylate cyclase activity gamma-aminobutyric acid signaling pathway synaptic transmission cell junction neuron projection synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
207018_s_at	0.185	2.294	2.684	1.684e-02	0.412	-3.095	RAB27B	RAB27B, member RAS oncogene family	18	50646837	NM_004163	5874	18q21.2	Hs.25318	14	nucleotide binding GTPase activity protein binding GTP binding Golgi apparatus small GTPase mediated signal transduction protein transport membrane
1553269_at	0.515	3.389	2.683	1.686e-02	0.412	-3.096	ZNF718	zinc finger protein 718	4	43276	CA411757	255403	4p16.3	Hs.428579 Hs.636638	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210407_at	-0.477	5.498	-2.683	1.687e-02	0.412	-3.096	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AF070670	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
226043_at	0.222	6.571	2.683	1.689e-02	0.412	-3.097	GPSM1	G-protein signaling modulator 1 (AGS3-like, C. elegans)	9	138341752, 138341752, 138367329	AI242661	26086	9q34.3	Hs.239370	14	GTPase activator activity binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane signal transduction multicellular organismal development nervous system development cell differentiation
211628_x_at	0.342	12.146	2.682	1.691e-02	0.412	-3.099	FTHP1	ferritin, heavy polypeptide pseudogene 1	6		J04755	2509	6p21.3-p12	Hs.453583	1
206710_s_at	0.863	4.228	2.681	1.693e-02	0.412	-3.099	EPB41L3	erythrocyte membrane protein band 4.1-like 3	18	-5382387	NM_012307	23136	18p11.32	Hs.213394	39	actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization	Tight junction
226531_at	-0.679	7.220	-2.681	1.693e-02	0.412	-3.099	ORAI1	ORAI calcium release-activated calcium modulator 1	12	120548837	AL530596	84876	12q24.31	Hs.55148	56	ion channel activity calcium ion binding protein binding plasma membrane integral to plasma membrane ion transport immune response store-operated calcium channel activity positive regulation of calcium ion transport
202390_s_at	0.230	6.075	2.681	1.694e-02	0.412	-3.100	HTT	huntingtin	4	3046205	NM_002111	3064	4p16.3	Hs.518450	252	urea cycle citrulline metabolic process transcription corepressor activity transporter activity calcium channel regulator activity protein binding soluble fraction nucleus cytoplasm Golgi apparatus protein import into nucleus ER to Golgi vesicle-mediated transport anti-apoptosis induction of apoptosis mitochondrion organization endoplasmic reticulum organization dopamine receptor signaling pathway spermatogenesis gastrulation brain development cell aging locomotory behavior microtubule binding axon cargo transport associative learning determination of adult lifespan visual learning pathogenesis embryonic development organ morphogenesis anterior/posterior pattern formation cytoplasmic membrane-bounded vesicle endosome transport inclusion body lactate biosynthetic process from pyruvate quinolinate biosynthetic process striatum development olfactory lobe development neural plate formation neurogenesis insulin secretion axon social behavior hormone metabolic process negative regulation of neuron apoptosis regulation of mitochondrial membrane permeability vesicle transport along microtubule regulation of synaptic plasticity paraxial mesoderm formation neuron development diazepam binding response to calcium ion regulation of mitochondrial membrane potential L-glutamate import iron ion homeostasis	Huntington's disease
202954_at	0.248	4.464	2.681	1.694e-02	0.412	-3.100	UBE2C	ubiquitin-conjugating enzyme E2C	20	43874661, 43875078	NM_007019	11065	20q13.12	Hs.93002	33	nucleotide binding ubiquitin-protein ligase activity ATP binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process cell cycle spindle organization mitosis cyclin catabolic process protein ubiquitination ligase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of exit from mitosis phosphoinositide-mediated signaling regulation of protein metabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Ubiquitin mediated proteolysis
207312_at	-0.831	7.698	-2.681	1.695e-02	0.412	-3.101	PHKG1	phosphorylase kinase, gamma 1 (muscle)	7	-56116168	NM_006213	5260	7p11.2	Hs.715728	23	nucleotide binding protein serine/threonine kinase activity phosphorylase kinase activity calmodulin binding ATP binding phosphorylase kinase complex carbohydrate metabolic process glycogen biosynthetic process protein amino acid phosphorylation transferase activity	Calcium signaling pathway Insulin signaling pathway
212850_s_at	-0.575	5.496	-2.680	1.696e-02	0.412	-3.101	LRP4	low density lipoprotein receptor-related protein 4	11	-46834993	AA584297	4038	11p11.2-p12	Hs.4930	7	receptor activity calcium ion binding cellular_component endocytosis biological_process membrane integral to membrane
218689_at	0.265	4.961	2.680	1.696e-02	0.412	-3.101	FANCF	Fanconi anemia, complementation group F	11	-22600654	NM_022725	2188	11p15	Hs.713574	27	molecular_function protein binding cellular_component nucleus DNA repair response to DNA damage stimulus biological_process
213589_s_at	0.328	5.805	2.679	1.701e-02	0.413	-3.103	B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1	17	-78494955	AW468201	146712	17q25.3	Hs.718480	5	transferase activity, transferring glycosyl groups
218651_s_at	0.864	6.598	2.679	1.701e-02	0.413	-3.104	LARP6	La ribonucleoprotein domain family, member 6	15	-68930821, -68910942	NM_018357	55323	15q23	Hs.416755	5	RNA binding nucleus cytoplasm RNA processing ribonucleoprotein complex
201078_at	-0.429	7.859	-2.679	1.701e-02	0.413	-3.104	TM9SF2	transmembrane 9 superfamily member 2	13	98951728	NM_004800	9375	13q32.3	Hs.654824	9	endosome integral to plasma membrane transport membrane
209699_x_at	1.059	9.901	2.678	1.703e-02	0.413	-3.105	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	10	-5021964	U05598	1646	10p15-p14	Hs.460260 Hs.567256	35	cytoplasm lipid metabolic process prostaglandin metabolic process digestion steroid metabolic process oxidoreductase activity carboxylic acid binding bile acid binding 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity oxidation reduction	Metabolism of xenobiotics by cytochrome P450
206690_at	0.244	4.003	2.678	1.705e-02	0.413	-3.106	ACCN1	amiloride-sensitive cation channel 1, neuronal	17	-28364218, -28364218	NM_001094	40	17q12	Hs.368417	18	ion channel activity protein binding plasma membrane integral to plasma membrane ion transport sodium ion transport synaptic transmission central nervous system development peripheral nervous system development amiloride-sensitive sodium channel activity sodium ion binding	Taste transduction
209772_s_at	0.258	3.933	2.678	1.705e-02	0.413	-3.106	CD24	CD24 molecule	6	-19611913	X69397	100133941	6q21	Hs.644105 Hs.694721	65	response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation leukocyte migration during inflammatory response immune response-regulating cell surface receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptosis signal transducer activity protein binding membrane fraction plasma membrane oxygen and reactive oxygen species metabolic process heterophilic cell adhesion leukocyte adhesion elevation of cytosolic calcium ion concentration neuromuscular synaptic transmission negative regulation of neuroblast proliferation induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals apoptotic mitochondrial changes external side of plasma membrane Wnt receptor signaling pathway cell migration protein kinase binding carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity regulation of epithelial cell differentiation negative regulation of B cell proliferation neuron projection development anchored to membrane T cell costimulation anchored to external side of plasma membrane microvillus membrane B cell receptor transport into membrane raft chemokine receptor transport out of membrane raft negative regulation of transforming growth factor-beta3 production positive regulation of integrin activation positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPKKK cascade eukaryotic cell surface binding response to estrogen stimulus membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling cilium membrane
219643_at	-1.578	5.193	-2.678	1.706e-02	0.413	-3.106	LRP1B	low density lipoprotein-related protein 1B (deleted in tumors)	2	-140705465	NM_018557	53353	2q21.2	Hs.656461	14	receptor activity low-density lipoprotein receptor activity calcium ion binding protein binding membrane fraction receptor-mediated endocytosis protein transport membrane integral to membrane
242195_x_at	0.316	7.556	2.678	1.706e-02	0.413	-3.106	NUMBL	numb homolog (Drosophila)-like	19	-45863651	BE350811	9253	19q13.13-q13.2	Hs.326953	15	protein binding cytoplasm nervous system development neuroblast proliferation axonogenesis forebrain development adherens junction organization	Notch signaling pathway
227271_at	0.387	6.348	2.677	1.708e-02	0.413	-3.107	FGF11	fibroblast growth factor 11	17	7283412	AU151265	2256	17p13.1	Hs.655193	7	signal transduction cell-cell signaling nervous system development growth factor activity	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
235565_at	0.333	3.407	2.677	1.708e-02	0.413	-3.107	ZNF786	zinc finger protein 786	7	-148397665	N30616	136051	7q36.1	Hs.31743	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213569_at	0.261	5.432	2.677	1.709e-02	0.413	-3.108	ANGEL1	angel homolog 1 (Drosophila)	14	-76323338	AV705485	23357	14q24.3	Hs.497448	5
214975_s_at	-0.362	3.866	-2.676	1.710e-02	0.413	-3.108	MTMR1	myotubularin related protein 1	X	149612526	AK001816	8776	Xq28	Hs.347187	10	protein tyrosine phosphatase activity cellular_component plasma membrane dephosphorylation hydrolase activity phosphatase activity	Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways
230405_at	0.241	7.327	2.676	1.710e-02	0.413	-3.108	C5orf56	chromosome 5 open reading frame 56	5	131774571	AI143416	441108	5q31.1	Hs.658288	1
209657_s_at	-0.560	8.384	-2.675	1.713e-02	0.413	-3.110	HSF2	heat shock transcription factor 2	6	122762394	M65217	3298	6q22.31	Hs.158195	28	transcription factor activity transcription coactivator activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress spermatogenesis protein homodimerization activity sequence-specific DNA binding
1556448_a_at	-0.243	3.214	-2.675	1.716e-02	0.414	-3.111	LOC285370	hypothetical LOC285370	3	-10776168	AI357576	285370	3p25.3	Hs.157613	1
221589_s_at	0.684	8.211	2.674	1.717e-02	0.414	-3.112	ALDH6A1	aldehyde dehydrogenase 6 family, member A1	14	-73596624	AW612403	4329	14q24.3	Hs.293970	9	acyl-CoA binding methylmalonate-semialdehyde dehydrogenase (acylating) activity mitochondrion valine metabolic process oxidoreductase activity malonate-semialdehyde dehydrogenase (acetylating) activity thymine metabolic process brown fat cell differentiation oxidation reduction	Valine, leucine and isoleucine degradation Inositol phosphate metabolism Propanoate metabolism Metabolic pathways
208758_at	-0.463	8.425	-2.674	1.717e-02	0.414	-3.112	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	2	215884936	D89976	471	2q35	Hs.90280	27	IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity protein binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process purine nucleotide biosynthetic process IMP biosynthetic process transferase activity hydrolase activity organ regeneration	Purine metabolism One carbon pool by folate Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
242870_at	0.262	3.249	2.674	1.718e-02	0.414	-3.113	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	BE551073	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
226718_at	-0.345	6.567	-2.673	1.723e-02	0.415	-3.115	AMIGO1	adhesion molecule with Ig-like domain 1	1	-109850968	AA001423	57463	1p13.3	Hs.709892	5	protein binding cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development nervous system development axonal fasciculation membrane integral to membrane cell differentiation axon myelination cell projection positive regulation of axonogenesis
206394_at	-1.245	12.029	-2.672	1.723e-02	0.415	-3.115	MYBPC2	myosin binding protein C, fast type	19	55627971	NM_004533	4606	19q13.33	Hs.85937	10	actin binding protein binding striated muscle thick filament striated muscle contraction cell adhesion structural constituent of muscle
213002_at	0.453	5.961	2.672	1.724e-02	0.415	-3.116	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	AA770596	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
205450_at	-0.751	8.175	-2.671	1.727e-02	0.415	-3.117	PHKA1	phosphorylase kinase, alpha 1 (muscle)	X	-71715388	NM_002637	5255	Xq12-q13	Hs.201379	12	catalytic activity phosphorylase kinase activity calmodulin binding cytoplasm plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy intracellular membrane-bounded organelle	Calcium signaling pathway Insulin signaling pathway
209184_s_at	-0.889	7.140	-2.671	1.728e-02	0.415	-3.117	IRS2	insulin receptor substrate 2	13	-109204184	BF700086	8660	13q34	Hs.442344	118	positive regulation of mesenchymal cell proliferation signal transducer activity insulin receptor binding plasma membrane signal transduction brain development insulin receptor signaling pathway negative regulation of plasma membrane long-chain fatty acid transport positive regulation of glucose metabolic process regulation of lipid metabolic process protein kinase binding protein domain specific binding positive regulation of cell migration mammary gland development positive regulation of fatty acid beta-oxidation response to peptide hormone stimulus phosphoinositide 3-kinase binding positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of glucose import lipid homeostasis	Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus
242528_at	0.210	3.103	2.670	1.731e-02	0.415	-3.119	LOC285943	hypothetical protein LOC285943	7		AI473887	285943	7p15.2	Hs.714774	1
222660_s_at	-0.211	3.727	-2.670	1.731e-02	0.415	-3.119	RNF38	ring finger protein 38	9	-36326398, -36326398, -36326398	AL136817	152006	9p13	Hs.333503	12	protein binding zinc ion binding metal ion binding
242297_at	0.289	5.750	2.670	1.732e-02	0.415	-3.119	RREB1	ras responsive element binding protein 1	6	7053186	BF904033	6239	6p25	Hs.298248	13	DNA binding intracellular nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter Ras protein signal transduction multicellular organismal development zinc ion binding transcription activator activity nuclear speck metal ion binding
226969_at	-0.254	8.004	-2.670	1.732e-02	0.415	-3.120	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase	1	235025203	AV706396	4548	1q43	Hs.498187	219	dihydropteroate synthase activity protein binding intracellular cytoplasm cytosol nervous system development methyltransferase activity zinc ion binding cellular amino acid biosynthetic process methionine synthase activity methionine synthase activity homocysteine S-methyltransferase activity methionine biosynthetic process folic acid and derivative biosynthetic process transferase activity cobalamin binding cellular metabolic process metal ion binding cobalt ion binding	Cysteine and methionine metabolism One carbon pool by folate Metabolic pathways
226120_at	0.292	4.104	2.670	1.733e-02	0.415	-3.120	TTC8	tetratricopeptide repeat domain 8	14	88360730	AW293939	123016	14q31.3	Hs.303055	7	binding cytoplasm centrosome plasma membrane cilium visual perception cell projection organization BBSome response to stimulus cilium membrane
200071_at	-0.483	8.339	-2.669	1.735e-02	0.415	-3.121	SMNDC1	survival motor neuron domain containing 1	10	-112042787	BF224259	10285	10q23	Hs.632093	12	spliceosome assembly RNA binding protein binding nucleus spliceosomal complex cytoplasm mRNA processing apoptosis induction of apoptosis RNA splicing Cajal body nuclear speck RNA splicing factor activity, transesterification mechanism
207306_at	-0.357	5.753	-2.669	1.735e-02	0.415	-3.121	TCF15	transcription factor 15 (basic helix-loop-helix)	20	-532636	NM_004609	6939	20p13	Hs.437	4	somitogenesis respiratory system process transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter multicellular organismal development death tail morphogenesis eating behavior ear development skin development regulation of transcription paraxial mesoderm development muscle organ morphogenesis skeletal system morphogenesis neuromuscular process controlling posture
203627_at	-0.645	4.933	-2.669	1.737e-02	0.415	-3.122	IGF1R	insulin-like growth factor 1 receptor	15	97010283	AI830698	3480	15q26.3	Hs.643120 Hs.653608 Hs.714012	315	nucleotide binding receptor activity insulin-like growth factor receptor activity insulin receptor binding ATP binding microsome integral to plasma membrane anti-apoptosis immune response signal transduction brain development positive regulation of cell proliferation insulin receptor signaling pathway organ morphogenesis phosphoinositide 3-kinase cascade membrane transferase activity male sex determination positive regulation of cell migration mammary gland development insulin-like growth factor I binding identical protein binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of DNA replication protein amino acid autophosphorylation insulin-like growth factor receptor signaling pathway phosphoinositide-mediated signaling protein tetramerization	Endocytosis Focal adhesion Adherens junction Long-term depression Pathways in cancer Colorectal cancer Glioma Prostate cancer Melanoma
1569069_s_at	-0.336	6.322	-2.668	1.738e-02	0.415	-3.123	TDRD3	tudor domain containing 3	13	59868591, 59869427	BC020604	81550	13q21.2	Hs.525061	12	nucleic acid binding nucleus cytoplasm
218378_s_at	0.281	7.029	2.668	1.739e-02	0.415	-3.123	PRKRIP1	PRKR interacting protein 1 (IL11 inducible)	7	101823808	NM_024653	79706	7q22.1	Hs.406395	6	double-stranded RNA binding protein kinase inhibitor activity protein binding nucleus nucleolus negative regulation of protein kinase activity protein kinase binding negative regulation of phosphorylation
227678_at	-0.914	6.963	-2.668	1.740e-02	0.416	-3.124	XRCC6BP1	XRCC6 binding protein 1	12	56621711	AI628122	91419	12q14.1	Hs.61188	3	DNA-dependent protein kinase activity DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
229106_at	0.311	6.218	2.668	1.740e-02	0.416	-3.124	DYNLL2	dynein, light chain, LC8-type 2	17	53515778	AA401429	140735	17q22	Hs.514368	12	microtubule motor activity protein binding cytoplasm cytosol microtubule plasma membrane microtubule-based process myosin complex dynein complex
203498_at	0.877	8.886	2.667	1.742e-02	0.416	-3.125	RCAN2	regulator of calcineurin 2	6	-46296427	NM_005822	10231	6p21.1-p12.3	Hs.440168	12	cellular_component central nervous system development calcium-mediated signaling protein phosphatase 2B binding
216008_s_at	-0.285	7.424	-2.666	1.745e-02	0.416	-3.126	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	AV694434	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
207814_at	0.205	5.797	2.666	1.746e-02	0.416	-3.127	DEFA6	defensin, alpha 6, Paneth cell-specific	8	-6769628	NM_001926	1671	8pter-p21	Hs.711	10	extracellular region extracellular space xenobiotic metabolic process defense response to bacterium defense response to fungus
213666_at	0.313	4.713	2.666	1.748e-02	0.416	-3.127	SEPT6	septin 6	X	-118634936, -118633715	AK026589	23157	Xq24	Hs.496666	22	nucleotide binding cytokinesis protein binding protein binding GTP binding cellular_component cell cycle septin complex
219072_at	0.261	7.336	2.664	1.754e-02	0.417	-3.131	BCL7C	B-cell CLL/lymphoma 7C	16	-30806616	NM_004765	9274	16p11	Hs.658547	9	apoptosis
226748_at	-0.591	8.208	-2.664	1.755e-02	0.417	-3.131	LYSMD2	LysM, putative peptidoglycan-binding, domain containing 2	15	-49802553, -49802553	AI674731	256586	15q21.2	Hs.631693	3	cell wall macromolecule catabolic process
242282_at	-0.190	6.080	-2.663	1.756e-02	0.417	-3.132	ZFPM1	zinc finger protein, multitype 1	16	87047514	AI889717	161882	16q24.2	Hs.632218	12	DNA binding protein binding intracellular nucleus heart development zinc ion binding regulation of transcription metal ion binding
227094_at	0.399	7.684	2.663	1.756e-02	0.417	-3.132	DHTKD1	dehydrogenase E1 and transketolase domain containing 1	10	12150939	AI934407	55526	10p14	Hs.104980 Hs.711138	3	oxoglutarate dehydrogenase (succinyl-transferring) activity mitochondrion glycolysis oxidoreductase activity thiamin pyrophosphate binding oxidation reduction
216594_x_at	1.055	9.978	2.663	1.756e-02	0.417	-3.132	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	10	4995453	S68290	1645	10p15-p14	Hs.460260	37	aldo-keto reductase activity cytoplasm cytosol xenobiotic metabolic process digestion bile acid metabolic process bile acid and bile salt transport oxidoreductase activity intestinal cholesterol absorption carboxylic acid binding bile acid binding cholesterol homeostasis response to organophosphorus 20-alpha-hydroxysteroid dehydrogenase activity 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity indanol dehydrogenase activity protein homooligomerization oxidation reduction	Metabolism of xenobiotics by cytochrome P450
228425_at	0.528	4.928	2.663	1.757e-02	0.417	-3.132	LOC654433	hypothetical LOC654433	2	113710316	BF056746	654433	2q13	Hs.656660	4
206156_at	0.223	3.596	2.662	1.760e-02	0.418	-3.134	GJB5	gap junction protein, beta 5, 31.1kDa	1	34993307	NM_005268	2709	1p35.1	Hs.198249	5	plasma membrane connexon complex cell communication epidermis development integral to membrane cell junction
206349_at	0.756	5.306	2.661	1.762e-02	0.418	-3.135	LGI1	leucine-rich, glioma inactivated 1	10	95507555	NM_005097	9211	10q24	Hs.533670	31	protein binding extracellular region nervous system development cell proliferation
203022_at	0.363	5.552	2.661	1.765e-02	0.418	-3.136	RNASEH2A	ribonuclease H2, subunit A	19	12778427	NM_006397	10535	19p13.2	Hs.532851	8	RNA binding endonuclease activity ribonuclease H activity ribonuclease activity nucleus DNA replication RNA catabolic process hydrolase activity metal ion binding	DNA replication
202824_s_at	-0.228	10.120	-2.661	1.765e-02	0.418	-3.136	TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8	-75021187	NM_005648	6921	8q21.11	Hs.554594	46	protein binding nucleus nucleoplasm cytosol regulation of transcription from RNA polymerase II promoter ubiquitin-dependent protein catabolic process interspecies interaction between organisms regulation of transcription	Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma
202058_s_at	-0.656	5.315	-2.660	1.766e-02	0.418	-3.137	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	BC002374	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
229707_at	0.355	4.717	2.660	1.766e-02	0.418	-3.137	ZNF606	zinc finger protein 606	19	-63180252	AI817719	80095	19q13.4	Hs.654967	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
36475_at	0.265	6.783	2.660	1.766e-02	0.418	-3.137	GCAT	glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)	22	36533900	Z97630	23464	22q13.1	Hs.54609	6	mitochondrion mitochondrial inner membrane cellular amino acid metabolic process acyltransferase activity glycine C-acetyltransferase activity biosynthetic process transferase activity, transferring nitrogenous groups pyridoxal phosphate binding	Glycine, serine and threonine metabolism
210282_at	0.611	3.368	2.660	1.768e-02	0.418	-3.138	ZMYM2	zinc finger, MYM-type 2	13	19430809	AL136621	7750	13q11-q12	Hs.644041	29	protein binding cellular_component nucleus biological_process zinc ion binding PML body ubiquitin conjugating enzyme binding regulation of transcription metal ion binding
208656_s_at	-0.268	9.947	-2.659	1.769e-02	0.418	-3.138	CCNI	cyclin I	4	-78188198	AF135162	10983	4q21.1	Hs.518827	7	spermatogenesis
208079_s_at	1.124	6.686	2.659	1.769e-02	0.418	-3.138	AURKA	aurora kinase A	20	-54377851	NM_003158	6790	20q13.2-q13.3	Hs.250822	196	nucleotide binding mitotic cell cycle protein serine/threonine kinase activity protein binding protein binding ATP binding nucleus centrosome spindle protein amino acid phosphorylation spindle organization mitosis transferase activity ubiquitin protein ligase binding regulation of protein stability phosphoinositide-mediated signaling
238987_at	-0.296	4.901	-2.658	1.773e-02	0.418	-3.140	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	9	-33100638	AL574435	2683	9p13	Hs.272011	41	Golgi trans cisterna epithelial cell development acute inflammatory response beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity N-acetyllactosamine synthase activity lactose synthase activity extracellular region Golgi apparatus plasma membrane carbohydrate metabolic process lactose biosynthetic process galactose metabolic process protein amino acid terminal N-glycosylation cell adhesion binding of sperm to zona pellucida penetration of zona pellucida cytoskeletal protein binding negative regulation of cell proliferation glycoprotein biosynthetic process oligosaccharide biosynthetic process oligosaccharide biosynthetic process external side of plasma membrane integral to membrane basolateral plasma membrane transferase activity, transferring glycosyl groups desmosome glycocalyx manganese ion binding extracellular matrix organization mammary gland development brush border membrane development of secondary sexual characteristics metal ion binding branching morphogenesis of a tube leukocyte migration regulation of cell motion regulation of acrosome reaction positive regulation of epithelial cell proliferation involved in wound healing angiogenesis involved in wound healing positive regulation of apoptosis involved in mammary gland involution	Galactose metabolism N-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
218999_at	-0.573	7.217	-2.658	1.775e-02	0.418	-3.141	TMEM140	transmembrane protein 140	7	134483363	NM_018295	55281	7q33	Hs.719309	8	membrane integral to membrane
1555001_at	-0.309	3.417	-2.658	1.776e-02	0.418	-3.142	IQCF1	IQ motif containing F1	3	-51903932	BC034228	132141	3p21.2	Hs.671210	2
214921_at	0.318	3.365	2.657	1.777e-02	0.418	-3.142	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	10	-78314641, -78299364	U02632	3778	10q22.3	Hs.144795	89	magnesium ion binding response to hypoxia actin binding catalytic activity voltage-gated ion channel activity voltage-gated potassium channel activity calcium ion binding protein binding caveola ion transport potassium ion transport response to osmotic stress synaptic transmission sensory perception of sound circadian rhythm adult walking behavior voltage-gated potassium channel complex metabolic process external side of plasma membrane integral to membrane apical plasma membrane regulation of action potential in neuron cellular potassium ion homeostasis potassium ion binding regulation of aldosterone metabolic process response to carbon monoxide response to carbon monoxide regulation of membrane potential auditory receptor cell differentiation positive regulation of apoptosis terminal button postsynaptic membrane locomotor rhythm negative regulation of cell volume saliva secretion cell maturation neuromuscular process controlling balance response to calcium ion large conductance calcium-activated potassium channel activity eye blink reflex smooth muscle contraction involved in micturition relaxation of vascular smooth muscle	Vascular smooth muscle contraction
232442_at	-0.323	4.963	-2.657	1.777e-02	0.418	-3.142	LOC100131601	similar to hCG1980470	16		AU147442	100131601	16q23.1	Hs.479747 Hs.711220	1
217356_s_at	-0.642	10.442	-2.657	1.777e-02	0.418	-3.142	PGK1	phosphoglycerate kinase 1	X	77246321	S81916	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
223758_s_at	0.597	6.231	2.657	1.777e-02	0.418	-3.142	GTF2H2	general transcription factor IIH, polypeptide 2, 44kDa	5	-70366706, 68891809, -972814, 350570	BC005345	2966	5q12.2-q13.3	Hs.191356 Hs.655216	52	nucleotide-excision repair, DNA damage removal transcription factor activity nucleus nucleoplasm DNA repair transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter response to DNA damage stimulus translation factor activity, nucleic acid binding zinc ion binding response to UV regulation of transcription metal ion binding protein N-terminus binding	Basal transcription factors Nucleotide excision repair
208215_x_at	0.297	5.327	2.657	1.779e-02	0.418	-3.143	DRD4	dopamine receptor D4	11	627304	NM_000797	1815	11p15.5	Hs.99922	339	activation of MAPK activity dopamine D4 receptor activity behavioral fear response response to amphetamine receptor activity G-protein coupled receptor activity protein binding plasma membrane integral to plasma membrane cellular calcium ion homeostasis signal transduction negative regulation of adenylate cyclase activity inhibition of adenylate cyclase activity by dopamine receptor signaling pathway drug binding adult locomotory behavior potassium channel regulator activity SH3 domain binding negative regulation of cAMP biosynthetic process positive regulation of sodium:hydrogen antiporter activity positive regulation of kinase activity response to histamine social behavior regulation of dopamine metabolic process behavioral response to cocaine behavioral response to ethanol arachidonic acid secretion negative regulation of protein secretion positive regulation of dopamine uptake negative regulation of calcium ion transport via voltage-gated calcium channel activity regulation of inhibitory postsynaptic membrane potential	Neuroactive ligand-receptor interaction
222992_s_at	0.236	12.030	2.657	1.779e-02	0.418	-3.143	NDUFB9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa	8	125620523	AF261090	4715	8q13.3	Hs.15977	13	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport sensory perception of sound NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
219134_at	0.509	6.497	2.657	1.779e-02	0.418	-3.143	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	1	-79128036	NM_022159	64123	1p33-p32	Hs.132314	9	G-protein coupled receptor activity G-protein coupled receptor activity calcium ion binding plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
1564837_at	-0.304	3.922	-2.656	1.780e-02	0.418	-3.144	LOC151760	hypothetical LOC151760	3		BC038577	151760	3q13.13	Hs.124136	1
218466_at	-0.271	6.675	-2.656	1.780e-02	0.418	-3.144	TBC1D17	TBC1 domain family, member 17	19	55072640	NM_024682	79735	19q13.33	Hs.631587	7	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
215447_at	0.395	3.836	2.656	1.781e-02	0.418	-3.144	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	2	-188051550, -188037202	AL080215	7035	2q32	Hs.516578	118	serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway	Complement and coagulation cascades
217725_x_at	-0.493	8.721	-2.655	1.784e-02	0.418	-3.145	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	NM_015640	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
229452_at	0.310	7.104	2.655	1.786e-02	0.418	-3.146	TMEM88	transmembrane protein 88	17	7699108	AL544576	92162	17p13.1	Hs.389669	2	membrane integral to membrane
232012_at	0.284	6.039	2.655	1.786e-02	0.418	-3.147	CAPN1	calpain 1, (mu/I) large subunit	11	64705918	AV691296	823	11q13	Hs.502842	78	calcium-dependent cysteine-type endopeptidase activity calcium ion binding protein binding intracellular cytoplasm plasma membrane proteolysis peptidase activity positive regulation of cell proliferation	Apoptosis Alzheimer's disease
225782_at	-0.585	9.363	-2.655	1.786e-02	0.418	-3.147	MSRB3	methionine sulfoxide reductase B3	12	63958754	AW027333	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
225811_at	-0.360	9.799	-2.655	1.786e-02	0.418	-3.147	C11orf58	chromosome 11 open reading frame 58	11	16716723	AI652868	10944	11p15.1	Hs.719128	8	molecular_function cellular_component biological_process
236994_at	-0.815	4.327	-2.654	1.787e-02	0.418	-3.147	FBXL4	F-box and leucine-rich repeat protein 4	6	-99428321	AW770868	26235	6q16.1-q16.3	Hs.536850	6	ubiquitin ligase complex nucleus cytoplasm ubiquitin-dependent protein catabolic process
218929_at	-0.446	5.933	-2.653	1.791e-02	0.418	-3.149	CDKN2AIP	CDKN2A interacting protein	4	184602782	NM_017632	55602	4q35.1	Hs.699392	10	granular component p53 binding double-stranded RNA binding intracellular nucleus nucleoplasm nucleolus positive regulation of signal transduction negative regulation of cell growth regulation of protein stability
203408_s_at	-0.611	9.727	-2.653	1.792e-02	0.418	-3.149	SATB1	SATB homeobox 1	3	-18364269, -18364269	NM_002971	6304	3p23	Hs.517717	34	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent sequence-specific DNA binding
210596_at	-0.272	6.170	-2.653	1.792e-02	0.418	-3.150	MAGT1	magnesium transporter 1	X	-76968519	AF130104	84061	Xq21.1	Hs.323562 Hs.710189	14	dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum oligosaccharyltransferase complex membrane integral to membrane protein amino acid N-linked glycosylation via asparagine
226459_at	0.363	4.705	2.653	1.793e-02	0.418	-3.150	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	10	-98343058	AW575754	118788	10q24.1	Hs.310456	9	transmembrane receptor protein tyrosine kinase signaling protein activity protein binding cytoplasm plasma membrane	B cell receptor signaling pathway
215926_x_at	0.326	6.627	2.652	1.795e-02	0.418	-3.151	SNAPC4	small nuclear RNA activating complex, polypeptide 4, 190kDa	9	-138389849	AK023513	6621	9q34.3	Hs.113265	11	transcription factor activity nucleus snRNA-activating protein complex snRNA transcription from RNA polymerase II promoter snRNA transcription from RNA polymerase III promoter regulation of transcription
200894_s_at	-0.374	6.051	-2.652	1.795e-02	0.418	-3.151	FKBP4	FK506 binding protein 4, 59kDa	12	2774368	AA894574	2288	12p13.33	Hs.524183 Hs.713721	47	peptidyl-prolyl cis-trans isomerase activity ATP binding GTP binding FK506 binding intracellular nucleus nucleolus cytoplasm protein folding steroid hormone receptor complex assembly copper ion transport embryo implantation isomerase activity protein binding, bridging heat shock protein binding protein complex localization glucocorticoid receptor binding male sex differentiation phosphoprotein binding
218921_at	-0.279	5.578	-2.652	1.796e-02	0.418	-3.152	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	11	-395715, -395715	NM_021805	59307	11p15.5	Hs.501624	13	negative regulation of cytokine-mediated signaling pathway transmembrane receptor activity protein binding acute-phase response signal transduction membrane integral to membrane negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation of transcription factor activity negative regulation of chemokine biosynthetic process innate immune response
228383_at	-0.347	5.970	-2.651	1.798e-02	0.419	-3.153	PNPLA7	patatin-like phospholipase domain containing 7	9	-139474225	AK024443	375775	9q34.3	Hs.294147	6	nucleus mitochondrion lysosome endoplasmic reticulum microsome lipid metabolic process metabolic process membrane integral to membrane hydrolase activity
216248_s_at	-1.119	3.467	-2.650	1.802e-02	0.419	-3.154	NR4A2	nuclear receptor subfamily 4, group A, member 2	2	-156889189	S77154	4929	2q22-q23	Hs.563344	76	transcription factor activity steroid hormone receptor activity nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding cellular response to extracellular stimulus sequence-specific DNA binding metal ion binding response to protein stimulus
239843_at	-0.255	3.550	-2.650	1.802e-02	0.419	-3.155	RIT1	Ras-like without CAAX 1	1	-154134224	AI655057	6016	1q22	Hs.491234	17	nucleotide binding calmodulin binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction small GTPase mediated signal transduction
221487_s_at	-0.726	7.202	-2.649	1.806e-02	0.420	-3.157	ENSA	endosulfine alpha	1	-148866145, -148862377, -148862377, -148861222, -148861222	AF157510	2029	1q21.3	Hs.632456	15	receptor binding cytoplasm transport response to nutrient ion channel inhibitor activity
202352_s_at	-0.263	8.329	-2.649	1.807e-02	0.420	-3.157	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	17	-62767081, -62767080	AI446530	5718	17q24.2	Hs.646575	39	protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
225649_s_at	-0.668	6.829	-2.649	1.808e-02	0.420	-3.158	STK35	serine/threonine kinase 35	20	2031518	AA001414	140901	20p13	Hs.100057	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity
241812_at	-0.342	5.277	-2.649	1.808e-02	0.420	-3.158	SPATS2L	spermatogenesis associated, serine-rich 2-like	2	200878848, 200879229, 200879600	AV648669	26010	2q33.1	Hs.120323	9
218177_at	-0.429	5.945	-2.648	1.810e-02	0.420	-3.159	CHMP1B	chromatin modifying protein 1B	18	11841388	AA293502	57132	18p11.21	Hs.656244	16	cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division	Endocytosis
225554_s_at	-0.255	7.452	-2.648	1.812e-02	0.420	-3.159	ANAPC7	anaphase promoting complex subunit 7	12	-109297656, -109295087	AA131793	51434	12q24.11	Hs.524741	30	binding nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
222921_s_at	-0.311	6.677	-2.647	1.813e-02	0.420	-3.160	HEY2	hairy/enhancer-of-split related with YRPW motif 2	6	126112424	AF232238	23493	6q21	Hs.144287	23	transcription factor activity nucleus regulation of transcription, DNA-dependent Notch signaling pathway multicellular organismal development nervous system development organ morphogenesis
215268_at	0.545	3.981	2.647	1.815e-02	0.420	-3.161	KIAA0754	KIAA0754	1	39647762	AW663712	643314	1p34.3	Hs.658760	1
1569129_s_at	0.284	5.512	2.646	1.816e-02	0.420	-3.161	C3orf38	chromosome 3 open reading frame 38	3	88281582	BC016013	285237	3p11.1	Hs.476944 Hs.518099	2	apoptosis
212116_at	0.261	5.761	2.646	1.816e-02	0.420	-3.162	TRIM27	tripartite motif-containing 27	6	-28978757, -330309, -128126	NM_006510	5987	6p22	Hs.440382	27	negative regulation of transcription from RNA polymerase II promoter DNA binding transmembrane receptor protein tyrosine kinase activity protein binding intracellular membrane fraction nucleus nucleoplasm cytoplasm integral to plasma membrane spermatogenesis zinc ion binding cell proliferation nuclear membrane regulation of transcription negative regulation of gene expression, epigenetic metal ion binding protein trimerization
230331_at	-0.591	4.051	-2.646	1.817e-02	0.420	-3.162	C13orf39	chromosome 13 open reading frame 39	13	-102136097	AI333373	196541	13q33.1	Hs.508623	1
212261_at	-0.184	7.311	-2.645	1.821e-02	0.420	-3.164	GIGYF2	GRB10 interacting GYF protein 2	2	233270258	AB014542	26058	2q37.1	Hs.565319	23	protein binding
1564254_at	-0.192	5.437	-2.645	1.823e-02	0.420	-3.165	KY	kyphoscoliosis peptidase	3	-135801454	AK090526	339855	3q22.2	Hs.146730	4	cytoplasm cytoskeleton peptidase activity
233647_s_at	0.336	6.259	2.644	1.823e-02	0.420	-3.165	CDADC1	cytidine and dCMP deaminase domain containing 1	13	48720103	AL138875	81602	13q14.2	Hs.388220	2	zinc ion binding hydrolase activity metal ion binding
1556724_at	0.178	5.373	2.644	1.824e-02	0.420	-3.165	LOC100128398	hypothetical protein LOC100128398	19		BC036750	100128398	19q13.43	Hs.655081	1
218373_at	-0.344	9.125	-2.644	1.824e-02	0.420	-3.165	AKTIP	AKT interacting protein	16	-52082692	NM_022476	64400	16q12.2	Hs.380897	14	protein binding cytoplasm plasma membrane apoptosis endosome organization lysosome organization endosome to lysosome transport protein transport small conjugating protein ligase activity HOPS complex post-translational protein modification early endosome to late endosome transport regulation of protein metabolic process FHF complex
230057_at	-0.346	6.258	-2.644	1.824e-02	0.420	-3.165	LOC285178	hypothetical protein LOC285178	2		AI609832	285178	2q35	Hs.586683	1
204359_at	0.485	8.107	2.644	1.826e-02	0.421	-3.166	FLRT2	fibronectin leucine rich transmembrane protein 2	14	85066240	NM_013231	23768	14q24-q32	Hs.533710 Hs.624735 Hs.719261	9	receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging
212665_at	-0.315	7.184	-2.642	1.831e-02	0.421	-3.168	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	3	157875072	AL556438	25976	3q25.31	Hs.719169	11	vasculogenesis kidney development nucleic acid binding NAD+ ADP-ribosyltransferase activity protein binding nucleus protein amino acid ADP-ribosylation nitrogen compound metabolic process zinc ion binding post-embryonic development transferase activity, transferring glycosyl groups hemopoiesis multicellular organismal metabolic process metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development palate development face morphogenesis
229809_at	-0.352	5.722	-2.642	1.831e-02	0.421	-3.169	POU6F1	POU class 6 homeobox 1	12	-49866986, -49866986	AW445212	5463	12q13.13	Hs.555886	10	transcription factor activity nucleus regulation of transcription, DNA-dependent brain development heart development muscle organ development sequence-specific DNA binding
225474_at	0.530	5.455	2.642	1.834e-02	0.422	-3.170	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	3	-65319983, -65314945	AI141556	9223	3p14.1	Hs.651939	24	nucleotide binding ATP binding plasma membrane cell-cell junction tight junction protein complex assembly cell adhesion cell surface receptor linked signal transduction protein C-terminus binding	Tight junction
202128_at	-0.348	6.577	-2.641	1.834e-02	0.422	-3.170	KIAA0317	KIAA0317	14	-74197707	NM_014821	9870	14q24.3	Hs.497417	4	intracellular protein modification process membrane integral to membrane acid-amino acid ligase activity modification-dependent protein catabolic process
226098_at	0.297	6.606	2.641	1.835e-02	0.422	-3.171	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)	3	-161457481	AB037795	57560	3q25.33	Hs.478095	7	cytoplasm
226032_at	0.305	6.601	2.641	1.837e-02	0.422	-3.171	CASP2	caspase 2, apoptosis-related cysteine peptidase	7	142695523	AU153405	835	7q34-q35	Hs.368982	83	cysteine-type endopeptidase activity cellular_component intracellular proteolysis peptidase activity enzyme binding protein domain specific binding identical protein binding regulation of apoptosis protein maturation by peptide bond cleavage
205752_s_at	0.290	5.874	2.640	1.839e-02	0.422	-3.173	GSTM5	glutathione S-transferase mu 5	1	110056386	NM_000851	2949	1p13.3	Hs.75652	15	glutathione transferase activity cytoplasm metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
202372_at	-0.256	6.772	-2.640	1.839e-02	0.422	-3.173	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	BF240652	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
219144_at	-0.564	9.919	-2.640	1.840e-02	0.422	-3.173	DUSP26	dual specificity phosphatase 26 (putative)	8	-33568392	NM_024025	78986	8p12	Hs.8719	6	protein tyrosine phosphatase activity nucleus cytoplasm Golgi apparatus protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
235496_at	0.418	6.309	2.640	1.840e-02	0.422	-3.173	HRCT1	histidine rich carboxyl terminus 1	9	35896188	AI521254	646962	9p13.3	Hs.709734	1	membrane integral to membrane
210613_s_at	-0.263	7.987	-2.640	1.840e-02	0.422	-3.173	SYNGR1	synaptogyrin 1	22	38075899, 38075899, 38090120	BC000731	9145	22q13.1	Hs.216226	13	integral to plasma membrane membrane cell junction melanosome synapse
1555719_a_at	0.380	3.147	2.640	1.841e-02	0.422	-3.174	C3orf15	chromosome 3 open reading frame 15	3	120904558	AB063298	89876	3q12-q13.3	Hs.341906	8	protein binding cytoplasm mitochondrion
212829_at	0.268	5.744	2.639	1.842e-02	0.422	-3.174	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	10	-22863771	BE878277	5305	10p12.2	Hs.57079	24	nucleotide binding ATP binding cellular_component kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity phosphorylation transferase activity phosphatidylinositol metabolic process	Inositol phosphate metabolism Phosphatidylinositol signaling system Regulation of actin cytoskeleton
226024_at	0.250	8.761	2.639	1.842e-02	0.422	-3.174	COMMD1	copper metabolism (Murr1) domain containing 1	2	61986306	BG481459	150684	2p15	Hs.468702	28	nucleus cytoplasm identical protein binding
235069_at	-0.499	5.672	-2.639	1.842e-02	0.422	-3.174	TATDN3	TatD DNase domain containing 3	1	211031792	AL525367	128387	1q32.3	Hs.530538	3	nuclease activity nucleus hydrolase activity endodeoxyribonuclease activity, producing 5'-phosphomonoesters
202779_s_at	-0.611	5.832	-2.639	1.844e-02	0.422	-3.175	UBE2S	ubiquitin-conjugating enzyme E2S	19	-60604461	NM_014501	27338	19q13.43	Hs.396393	6	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
224664_at	-0.239	10.834	-2.638	1.845e-02	0.422	-3.176	C10orf104	chromosome 10 open reading frame 104	10	73645811	BE962336	119504	10q22.1	Hs.426296	5
235634_at	0.265	5.179	2.638	1.846e-02	0.422	-3.176	PURG	purine-rich element binding protein G	8	-31007898, -30972862	BE503391	29942	8p11	Hs.373778	3	DNA binding nucleus
237378_at	0.220	5.706	2.638	1.847e-02	0.422	-3.177	FLJ46321	FAM75-like protein FLJ46321	9	83793506	AL040781	389763	9q21.32	Hs.209545		membrane integral to membrane
213597_s_at	0.188	2.947	2.637	1.851e-02	0.422	-3.178	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF002474	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
205600_x_at	0.327	5.285	2.637	1.852e-02	0.422	-3.179	HOXB5	homeobox B5	17	-44023617	AI052747	3215	17q21.3	Hs.654456	25	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anatomical structure morphogenesis anterior/posterior pattern formation sequence-specific DNA binding endothelial cell differentiation embryonic skeletal system morphogenesis
1555548_at	0.265	4.621	2.636	1.853e-02	0.422	-3.179	NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	2	-240548828	AF453834	4705	2q37.3	Hs.277677	11	ATP binding mitochondrion mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transport NADH dehydrogenase (ubiquinone) activity phosphotransferase activity, alcohol group as acceptor electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
206314_at	0.310	4.170	2.636	1.854e-02	0.422	-3.180	ZNF167	zinc finger protein 167	3	44571716, 44571716	NM_018651	55888	3p22.3-p21.1	Hs.529512 Hs.696570	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
219653_at	0.239	5.830	2.635	1.857e-02	0.422	-3.181	LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)	20	60130911	NM_014054	149986	20q13.33	Hs.105379	5
228306_at	0.360	6.755	2.635	1.858e-02	0.422	-3.181	CNIH4	cornichon homolog 4 (Drosophila)	1	222611217	T87074	29097	1q42.11	Hs.195403 Hs.445890	11	protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane
222242_s_at	0.212	4.443	2.635	1.858e-02	0.422	-3.181	KLK5	kallikrein-related peptidase 5	19	-56138370	AF243527	25818	19q13.3-q13.4	Hs.50915	37	serine-type endopeptidase activity serine-type endopeptidase activity extracellular region extracellular space proteolysis peptidase activity epidermis development positive regulation of G-protein coupled receptor protein signaling pathway
220170_at	-0.485	4.394	-2.635	1.859e-02	0.422	-3.182	FHL5	four and a half LIM domains 5	6	97117155	NM_020482	9457	6q16.1-q16.3	Hs.632608	18	transcription coactivator activity nucleus zinc ion binding metal ion binding
238848_at	-0.295	3.418	-2.635	1.860e-02	0.422	-3.182	OTUD4	OTU domain containing 4	4	-146299738, -146274251	BF750565	54726	4q31.21	Hs.270851	13	molecular_function protein binding cellular_component biological_process
200719_at	-0.417	8.289	-2.634	1.861e-02	0.422	-3.183	SKP1	S-phase kinase-associated protein 1	5	-133519980	BE964043	6500	5q31	Hs.171626 Hs.710433	63	protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
237202_at	0.222	6.705	2.633	1.865e-02	0.423	-3.185	PGPEP1	pyroglutamyl-peptidase I	19	18312407	AI810572	54858	19p13.11	Hs.131776	8	cytoplasm proteolysis peptidase activity cysteine-type peptidase activity
225728_at	0.643	5.013	2.633	1.865e-02	0.423	-3.185	SORBS2	sorbin and SH3 domain containing 2	4	-186743592, -186743592, -186743592, -186743592, -186743592, -186743591, -186743591	AI659533	8470	4q35.1	Hs.619806 Hs.655143	30	structural constituent of cytoskeleton protein binding nucleus cytoplasm cytoskeletal adaptor activity biological_process structural constituent of muscle actin cytoskeleton Z disc perinuclear region of cytoplasm
1568702_a_at	0.289	6.598	2.632	1.868e-02	0.423	-3.186	PAAF1	proteasomal ATPase-associated factor 1	11	73265680	AI131457	80227	11q13.4	Hs.525017	9	protein binding cytosol protein complex interspecies interaction between organisms
224884_at	-0.499	6.762	-2.632	1.869e-02	0.423	-3.187	AKAP13	A kinase (PRKA) anchor protein 13	15	83724874, 84021271	AW575773	11214	15q24-q25	Hs.459211 Hs.710656	38	cAMP-dependent protein kinase activity signal transducer activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular membrane fraction nucleus cytoplasm intracellular signaling cascade biological_process zinc ion binding membrane diacylglycerol binding regulation of Rho protein signal transduction metal ion binding
225098_at	0.270	7.617	2.631	1.873e-02	0.424	-3.189	ABI2	abl-interactor 2	2	203901247	BF245400	10152	2q33	Hs.471156	22	DNA binding SH3/SH2 adaptor activity cytoplasm cytoplasm cytosol cytoskeleton cell motion cytoskeleton organization cytoskeletal adaptor activity actin polymerization or depolymerization cell migration SH3 domain binding peptidyl-tyrosine phosphorylation kinase binding lamellipodium filopodium	Regulation of actin cytoskeleton
219442_at	0.228	5.861	2.631	1.874e-02	0.424	-3.189	C16orf67	chromosome 16 open reading frame 67	16	31619434	NM_024048	100132341	16p11.2		4
227391_x_at	0.228	7.568	2.630	1.878e-02	0.425	-3.191	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2	238200962, 238265545, 238265545	BE674143	9208	2q37.3	Hs.471779	16	DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity
212250_at	-0.430	7.994	-2.628	1.884e-02	0.426	-3.194	MTDH	metadherin	8	98725582	AV700332	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
244070_at	-0.270	4.630	-2.628	1.885e-02	0.426	-3.195	SYNE1	spectrin repeat containing, nuclear envelope 1	6	-152484514, -152484514, -152484514, -152484514	AW300380	23345	6q25	Hs.12967	29	actin binding lamin binding nucleus nuclear envelope cytoplasm Golgi apparatus cytoskeleton nucleus organization Golgi organization cell death integral to membrane sarcomere muscle cell differentiation postsynaptic membrane
209362_at	-0.419	7.983	-2.628	1.886e-02	0.426	-3.195	MED21	mediator complex subunit 21	12	27066749	AI688580	9412	12p11.23	Hs.286145	27	blastocyst development RNA polymerase II transcription factor activity transcription coactivator activity DNA-directed RNA polymerase activity protein binding nucleus DNA-directed RNA polymerase II, core complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter
226989_at	-0.829	7.030	-2.628	1.886e-02	0.426	-3.195	RGMB	RGM domain family, member B	5	98132898	BE855765	285704	5q15	Hs.526902	5	ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane
225465_at	0.396	7.216	2.627	1.888e-02	0.426	-3.196	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	3	-65319983, -65314945	AK023358	9223	3p14.1	Hs.651939	24	nucleotide binding ATP binding plasma membrane cell-cell junction tight junction protein complex assembly cell adhesion cell surface receptor linked signal transduction protein C-terminus binding	Tight junction
224952_at	0.291	4.534	2.627	1.890e-02	0.426	-3.196	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	17	58440629	BF115054	26115	17q23.2-q23.3	Hs.410889	3	binding
200605_s_at	-0.531	9.785	-2.626	1.891e-02	0.426	-3.197	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	17	64019704, 64020137	NM_002734	5573	17q23-q24	Hs.280342	106	nucleotide binding mesoderm formation regulation of protein amino acid phosphorylation protein binding cAMP-dependent protein kinase complex regulation of transcription from RNA polymerase II promoter cAMP-dependent protein kinase regulator activity hormone-mediated signaling cAMP binding neuromuscular junction	Apoptosis Insulin signaling pathway
236635_at	0.536	4.890	2.626	1.891e-02	0.426	-3.197	ZNF667	zinc finger protein 667	19	-61643017	AI332774	63934	19q13.43	Hs.712574	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
223652_at	0.571	6.104	2.626	1.892e-02	0.426	-3.198	AS3MT	arsenic (+3 oxidation state) methyltransferase	10	104619199	AF226730	57412	10q24.32	Hs.34492	24	soluble fraction cytoplasm cytosol metabolic process methyltransferase activity toxin metabolic process transferase activity arsonoacetate metabolic process arsenite methyltransferase activity methylarsonite methyltransferase activity response to arsenic
226541_at	-0.347	6.966	-2.626	1.892e-02	0.426	-3.198	FBXO30	F-box protein 30	6	-146160964	AI808182	84085	6q24	Hs.421095	8	zinc ion binding modification-dependent protein catabolic process metal ion binding
205406_s_at	0.224	3.728	2.625	1.896e-02	0.427	-3.199	SPA17	sperm autoantigenic protein 17	11	124048949	NM_017425	53340	11q24.2	Hs.286233	19	signal transduction spermatogenesis single fertilization binding of sperm to zona pellucida cAMP-dependent protein kinase regulator activity membrane
208204_s_at	-0.560	9.284	-2.624	1.899e-02	0.427	-3.201	CAV3	caveolin 3	3	8750495	NM_001234	859	3p25	Hs.98303	73	membrane fraction Golgi apparatus caveola triglyceride metabolic process elevation of cytosolic calcium ion concentration muscle organ development protein C-terminus binding protein localization negative regulation of cardiac muscle hypertrophy regulation of skeletal muscle contraction dystrophin-associated glycoprotein complex integral to membrane cell growth sodium channel regulator activity Z disc cell differentiation T-tubule positive regulation of microtubule polymerization membrane raft organization neuromuscular junction protein complex binding protein complex scaffold T-tubule organization regulation of membrane potential glucose homeostasis cholesterol homeostasis negative regulation of MAP kinase activity negative regulation of MAPKKK cascade negative regulation of cell size muscle maintenance negative regulation of nitric-oxide synthase activity regulation of calcium ion transport via voltage-gated calcium channel activity negative regulation of sarcomere organization regulation of ventricular cardiomyocyte membrane repolarization	Focal adhesion
218534_s_at	-0.391	6.554	-2.624	1.901e-02	0.427	-3.202	AGGF1	angiogenic factor with G patch and FHA domains 1	5	76361987	NM_018046	55109	5q13.3	Hs.634849	12	vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm
210106_at	-0.267	6.762	-2.624	1.901e-02	0.427	-3.202	RDH5	retinol dehydrogenase 5 (11-cis/9-cis)	12	54400417	U43559	5959	12q13-q14	Hs.600940	28	retinol dehydrogenase activity binding endoplasmic reticulum lumen visual perception membrane oxidoreductase activity response to stimulus oxidation reduction	Retinol metabolism
203004_s_at	-0.205	6.401	-2.623	1.901e-02	0.427	-3.202	MEF2D	myocyte enhancer factor 2D	1	-154700142	NM_005920	4209	1q12-q23	Hs.314327	35	transcription factor activity nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding
206584_at	0.546	3.717	2.623	1.902e-02	0.427	-3.202	LY96	lymphocyte antigen 96	8	75066140	NM_015364	23643	8q21.11	Hs.660766	65	lipopolysaccharide receptor activity protein binding extracellular region extracellular space plasma membrane plasma membrane inflammatory response immune response cellular defense response cell surface receptor linked signal transduction I-kappaB kinase/NF-kappaB cascade coreceptor activity detection of lipopolysaccharide lipopolysaccharide receptor complex	Toll-like receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
201764_at	0.323	7.300	2.623	1.903e-02	0.427	-3.203	TMEM106C	transmembrane protein 106C	12	46643596	NM_024056	79022	12q13.1	Hs.596726	5	molecular_function cellular_component endoplasmic reticulum biological_process membrane integral to membrane
1561892_at	-0.228	2.713	-2.623	1.904e-02	0.427	-3.203	ZMYM6	zinc finger, MYM-type 6	1	-35224353	BC043174	9204	1p34.2	Hs.533986 Hs.623978 Hs.675613	8	DNA binding nucleus nucleolus multicellular organismal development zinc ion binding metal ion binding
221841_s_at	-1.033	7.092	-2.622	1.906e-02	0.428	-3.204	KLF4	Kruppel-like factor 4 (gut)	9	-109286953	BF514079	9314	9q31	Hs.376206	66	transcription factor activity intracellular nucleus nucleolus mesodermal cell fate determination zinc ion binding negative regulation of cell proliferation transcription activator activity transcription repressor activity regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding
220184_at	0.429	4.792	2.621	1.910e-02	0.428	-3.206	NANOG	Nanog homeobox	12	7833261	NM_024865	79923	12p13.31	Hs.661360	42	transcription factor activity nucleus regulation of transcription, DNA-dependent cell proliferation embryonic development sequence-specific DNA binding regulation of cell differentiation
224937_at	0.581	4.284	2.620	1.913e-02	0.429	-3.207	PTGFRN	prostaglandin F2 receptor negative regulator	1	117254211	BF311866	5738	1p13.1	Hs.418093	14	protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane
1554380_at	-0.196	4.998	-2.620	1.913e-02	0.429	-3.207	NEK11	NIMA (never in mitosis gene a)- related kinase 11	3	132228383, 132228383	AB071997	79858	3q22.1	Hs.657336	8	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding nucleus nucleolus protein amino acid phosphorylation cell cycle protein kinase cascade transferase activity manganese ion binding intra-S DNA damage checkpoint identical protein binding
212758_s_at	-0.479	8.044	-2.620	1.915e-02	0.429	-3.208	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	AI373166	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
238929_at	-0.296	5.174	-2.620	1.916e-02	0.429	-3.209	SFRS2B	splicing factor, arginine/serine-rich 2B	11	94439703	N30132	10929	11q22	Hs.476680 Hs.713908	6	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
203557_s_at	0.349	7.550	2.619	1.918e-02	0.429	-3.209	PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	10	-72313272	NM_000281	5092	10q22	Hs.3192	28	transcription coactivator activity phenylalanine 4-monooxygenase activity nucleus cytoplasm tetrahydrobiopterin biosynthetic process 4-alpha-hydroxytetrahydrobiopterin dehydratase activity lyase activity identical protein binding regulation of protein homodimerization activity positive regulation of transcription protein homotetramerization protein heterooligomerization
219565_at	-0.304	5.331	-2.618	1.922e-02	0.429	-3.211	CYP20A1	cytochrome P450, family 20, subfamily A, polypeptide 1	2	203811408	NM_020674	57404	2q33.2	Hs.446065 Hs.707756	7	monooxygenase activity electron carrier activity membrane integral to membrane heme binding metal ion binding oxidation reduction
1557430_at	0.363	3.019	2.618	1.922e-02	0.429	-3.212	LOC147670	hypothetical protein LOC147670	19		BG910569	147670	19q13.43	Hs.336588	1
222542_x_at	-0.657	6.701	-2.618	1.923e-02	0.429	-3.212	CABC1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	1	225194560	BF724826	56997	1q42.13	Hs.118241	10	nucleotide binding ATP binding mitochondrion cell death kinase activity transferase activity
214526_x_at	0.319	6.215	2.618	1.924e-02	0.429	-3.212	PMS2L1	postmeiotic segregation increased 2-like 1 pseudogene	7	-99756198	NM_005394	5379	7q22.1	Hs.634244 Hs.661055 Hs.709266	7	molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding
232892_at	0.366	9.816	2.617	1.924e-02	0.429	-3.213	C20orf166	chromosome 20 open reading frame 166	20	60558104	AL449263	128826	20q13.33	Hs.86507	5
1554469_at	0.313	4.351	2.617	1.924e-02	0.429	-3.213	ZBTB44	zinc finger and BTB domain containing 44	11	-129601783	BC030580	29068	11q24.3	Hs.719099	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203457_at	-0.276	5.895	-2.617	1.927e-02	0.429	-3.214	STX7	syntaxin 7	6	-132820355	NM_003569	8417	6q23.1	Hs.593148 Hs.605992	31	SNAP receptor activity endosome Golgi apparatus intracellular protein transport post-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
1554660_a_at	-0.457	3.918	-2.617	1.928e-02	0.429	-3.214	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	BC036200	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
209283_at	0.311	12.678	2.615	1.933e-02	0.430	-3.216	CRYAB	crystallin, alpha B	11	-111284559	AF007162	1410	11q22.3-q23.1	Hs.408767	143	structural constituent of eye lens soluble fraction insoluble fraction cytoplasm plasma membrane protein folding anti-apoptosis muscle contraction muscle organ development response to heat Z disc negative regulation of intracellular transport camera-type eye development contractile fiber unfolded protein binding protein homooligomerization
203090_at	-0.200	6.966	-2.614	1.937e-02	0.431	-3.218	SDF2	stromal cell-derived factor 2	17	-23999733	NM_006923	6388	17q11.2	Hs.514036	5	dolichyl-phosphate-mannose-protein mannosyltransferase activity extracellular region extracellular space protein amino acid glycosylation membrane
228718_at	0.355	5.727	2.612	1.946e-02	0.432	-3.222	ZNF44	zinc finger protein 44	19	-12243624	AI379070	51710	19p13.2	Hs.296731 Hs.693933	10	DNA binding protein binding intracellular nucleus cytoplasm cytoskeleton regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212470_at	-0.327	8.166	-2.612	1.947e-02	0.432	-3.223	SPAG9	sperm associated antigen 9	17	-46394534	AB011088	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
219428_s_at	0.204	6.736	2.612	1.947e-02	0.432	-3.223	PXMP4	peroxisomal membrane protein 4, 24kDa	20	-31754210	BF057649	11264	20q11.22	Hs.654857	8	membrane fraction peroxisome peroxisomal membrane membrane integral to membrane
212345_s_at	0.341	6.941	2.611	1.948e-02	0.432	-3.223	CREB3L2	cAMP responsive element binding protein 3-like 2	7	-137210264	BE675139	64764	7q34	Hs.719234	8	transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent response to unfolded protein membrane integral to membrane sequence-specific DNA binding protein dimerization activity	Melanogenesis Huntington's disease Prostate cancer
216525_x_at	0.270	6.741	2.611	1.949e-02	0.432	-3.224	PMS2L3	postmeiotic segregation increased 2-like 3	7	-74975005, -74975004	D38437	5387	7q11.23	Hs.406395 Hs.659871 Hs.661055	4	molecular_function nucleic acid binding ATP binding cellular_component intracellular regulation of transcription, DNA-dependent biological_process
242172_at	0.278	4.372	2.611	1.949e-02	0.432	-3.224	MEIS1	Meis homeobox 1	2	66516035	N50406	4211	2p14-p13	Hs.526754 Hs.603755	42	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding
215073_s_at	0.329	5.897	2.611	1.951e-02	0.432	-3.225	NR2F2	nuclear receptor subfamily 2, group F, member 2	15	94670160, 94675114, 94676797, 94677572	AL554245	7026	15q26	Hs.657455	27	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding
224250_s_at	-0.388	7.930	-2.610	1.955e-02	0.432	-3.226	SECISBP2	SECIS binding protein 2	9	91123231	BC001189	79048	9q22.2	Hs.59804	20	RNA binding mRNA 3'-UTR binding nucleus translation
1553860_at	0.249	4.564	2.609	1.958e-02	0.433	-3.228	DCST1	DC-STAMP domain containing 1	1	153272923	NM_152494	149095	1q22	Hs.567717	2	protein binding zinc ion binding membrane integral to membrane metal ion binding
227424_x_at	-0.316	6.524	-2.609	1.959e-02	0.433	-3.228	C21orf119	chromosome 21 open reading frame 119	21	32687312	AI800837	84996	21q22.11	Hs.58149	2
1567247_at	-0.301	2.562	-2.608	1.961e-02	0.433	-3.229	OR5H1	olfactory receptor, family 5, subfamily H, member 1	3	99334231	X64988	26341	3q11.2	Hs.537383	1	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus
224818_at	-0.320	8.719	-2.608	1.962e-02	0.433	-3.230	SORT1	sortilin 1	1	-109653714	BE622952	6272	1p21.3-p13.1	Hs.485195 Hs.703487	47	ossification receptor activity nucleus lysosome early endosome endoplasmic reticulum microsome Golgi apparatus plasma membrane coated pit transport Golgi to endosome transport endocytosis neuropeptide signaling pathway multicellular organismal development endosome to lysosome transport induction of apoptosis by extracellular signals cell surface nerve growth factor receptor activity regulation of gene expression myotube differentiation integral to membrane cytoplasmic membrane-bounded vesicle vesicle organization enzyme binding clathrin-coated vesicle cell differentiation neurotensin receptor activity, non-G-protein coupled endosome transport via multivesicular body sorting pathway response to insulin stimulus negative regulation of apoptosis glucose import nerve growth factor receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity	Lysosome Neurotrophin signaling pathway
221290_s_at	0.357	4.448	2.608	1.963e-02	0.433	-3.230	MUM1	melanoma associated antigen (mutated) 1	19	1305975, 1307322	NM_016473	84939	19p13.3	Hs.515016	6
217799_x_at	-0.297	7.183	-2.607	1.964e-02	0.433	-3.230	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	7	-129260230	NM_003344	7328	7q32	Hs.643548	16	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity regulation of protein metabolic process	Ubiquitin mediated proteolysis
214829_at	0.540	5.483	2.607	1.966e-02	0.434	-3.231	AASS	aminoadipate-semialdehyde synthase	7	-121500835	AK023446	10157	7q31.3	Hs.156738	10	binding mitochondrion electron carrier activity oxidoreductase activity L-lysine catabolic process saccharopine dehydrogenase (NADP+, L-lysine-forming) activity saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity protein tetramerization oxidation reduction	Lysine biosynthesis Lysine degradation Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
225171_at	-0.322	7.098	-2.606	1.968e-02	0.434	-3.232	ARHGAP18	Rho GTPase activating protein 18	6	-129939932	BE644830	93663	6q22.33	Hs.486458 Hs.708586	7	GTPase activator activity protein binding intracellular signal transduction
212502_at	-0.351	7.500	-2.606	1.968e-02	0.434	-3.232	ADO	2-aminoethanethiol (cysteamine) dioxygenase	10	64234521	AV713053	84890	10q21.3	Hs.99821	4	iron ion binding oxidoreductase activity metal ion binding cysteamine dioxygenase activity oxidation reduction	Taurine and hypotaurine metabolism Metabolic pathways
222954_at	-0.370	9.457	-2.606	1.969e-02	0.434	-3.233	FBXO40	F-box protein 40	3	122794859	AF204674	51725	3q13.33	Hs.272564	7	molecular_function cellular_component biological_process zinc ion binding modification-dependent protein catabolic process metal ion binding
201204_s_at	0.401	6.224	2.606	1.970e-02	0.434	-3.233	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	20	-17542322	AA706065	6238	20p12	Hs.472213	19	receptor activity endoplasmic reticulum ribosome translation signal transduction protein transport membrane integral to membrane integral to endoplasmic reticulum membrane intracellular protein transmembrane transport
208190_s_at	0.349	5.410	2.604	1.975e-02	0.435	-3.236	LSR	lipolysis stimulated lipoprotein receptor	19	40431398	NM_015925	51599	19q13.12	Hs.466507	11	liver development receptor activity nucleus nucleolus cytoplasm Golgi apparatus plasma membrane embryonic development integral to membrane very-low-density lipoprotein particle low-density lipoprotein particle chylomicron
211071_s_at	0.786	8.059	2.604	1.977e-02	0.435	-3.236	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	1	149298774	BC006471	10962	1q21	Hs.75823	9	molecular_function cellular_component
202309_at	0.279	8.723	2.604	1.977e-02	0.435	-3.237	MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	14	63924511	NM_005956	4522	14q24	Hs.652308	68	histidine biosynthetic process nucleotide binding formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity protein binding ATP binding cytoplasm mitochondrion purine nucleotide biosynthetic process histidine catabolic process one-carbon metabolic process cellular amino acid biosynthetic process methionine biosynthetic process folic acid and derivative biosynthetic process formyltetrahydrofolate dehydrogenase activity oxidoreductase activity hydrolase activity ligase activity oxidation reduction	Glyoxylate and dicarboxylate metabolism One carbon pool by folate Metabolic pathways
219975_x_at	0.222	2.435	2.603	1.981e-02	0.435	-3.238	OLAH	oleoyl-ACP hydrolase	10	15125900	NM_018324	55301	10p13	Hs.24309	4	oleoyl-[acyl-carrier-protein] hydrolase activity fatty acid biosynthetic process hydrolase activity, acting on ester bonds	Fatty acid biosynthesis Metabolic pathways
1552266_at	-0.198	2.725	-2.602	1.985e-02	0.436	-3.240	ADAM32	ADAM metallopeptidase domain 32	8	39084206	NM_145004	203102	8p11.22	Hs.521545	6	metalloendopeptidase activity proteolysis zinc ion binding membrane integral to membrane
217234_s_at	0.320	4.581	2.601	1.989e-02	0.436	-3.242	EZR	ezrin	6	-159106760, -159106760	AF199015	7430	6q25.2-q26	Hs.487027	158	ruffle cytoplasm cytosol actin filament plasma membrane microvillus cell cortex cytoskeletal anchoring at plasma membrane leukocyte adhesion cytoskeletal protein binding regulation of cell shape extrinsic to membrane membrane to membrane docking filopodium cortical cytoskeleton apical part of cell cell adhesion molecule binding actin filament binding actin filament bundle formation	Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
223567_at	0.222	3.275	2.601	1.990e-02	0.436	-3.242	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	19	-4493599	AB022433	10501	19p13.3	Hs.465642	4	receptor activity multicellular organismal development nervous system development membrane integral to membrane cell differentiation	Axon guidance
202847_at	0.682	4.676	2.601	1.990e-02	0.436	-3.242	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	14	23633322, 23633322	NM_004563	5106	14q11.2	Hs.75812	9	phosphoenolpyruvate carboxykinase (GTP) activity GTP binding mitochondrion gluconeogenesis lyase activity purine nucleotide binding manganese ion binding metal ion binding	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways PPAR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway
219714_s_at	0.584	5.935	2.600	1.991e-02	0.436	-3.243	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3	3	54131732	NM_018398	55799	3p21.1	Hs.656687	9	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
201366_at	-0.355	9.200	-2.600	1.994e-02	0.436	-3.244	ANXA7	annexin A7	10	-74805194	NM_004034	310	10q21.1-q21.2	Hs.631827	24	calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding
205488_at	0.291	3.903	2.598	2.000e-02	0.437	-3.247	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	5	54434230	NM_006144	3001	5q11-q12	Hs.90708	39	immunological synapse serine-type endopeptidase activity extracellular region nucleus proteolysis apoptosis cleavage of lamin immune response peptidase activity cytolysis protein homodimerization activity	Neuroactive ligand-receptor interaction
218552_at	0.343	8.683	2.598	2.001e-02	0.437	-3.247	ECHDC2	enoyl Coenzyme A hydratase domain containing 2	1	-53134491	NM_018281	55268	1p32.3	Hs.476319	2	mitochondrion lipid metabolic process fatty acid metabolic process metabolic process lyase activity
205030_at	1.776	6.423	2.598	2.001e-02	0.437	-3.247	FABP7	fatty acid binding protein 7, brain	6	123142344	NM_001446	2173	6q22-q23	Hs.26770	28	transporter activity cytoplasm transport nervous system development negative regulation of cell proliferation lipid binding	PPAR signaling pathway
205249_at	-0.293	3.235	-2.598	2.002e-02	0.437	-3.247	EGR2	early growth response 2	10	-64241765, -64241765	NM_000399	1959	10q21.1	Hs.1395	41	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent learning or memory rhythmic behavior motor axon guidance zinc ion binding Schwann cell differentiation rhombomere 3 development facial nerve structural organization rhombomere 3 formation rhombomere 5 formation regulation of ossification response to insulin stimulus brain segmentation myelination positive regulation of transcription from RNA polymerase II promoter metal ion binding regulation of neuronal synaptic plasticity
1553106_at	-0.439	2.812	-2.597	2.005e-02	0.438	-3.249	C5orf24	chromosome 5 open reading frame 24	5	134209268, 134209556	NM_152409	134553	5q31.1	Hs.406549	3
226065_at	0.349	6.761	2.596	2.009e-02	0.438	-3.251	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	N98595	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
226305_at	0.263	6.153	2.596	2.010e-02	0.438	-3.251	LYNX1	Ly6/neurotoxin 1	8	-143849616, -143849616, -143849616, -143842759, -143842757	AV696976	66004	8q24.3	Hs.158665 Hs.604828	9	extracellular region plasma membrane anchored to membrane
205193_at	-0.831	5.487	-2.595	2.012e-02	0.438	-3.252	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	22	36927884, 36928972	NM_012323	23764	22q13.1	Hs.517617	14	in utero embryonic development transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress parturition sequence-specific DNA binding regulation of epidermal cell differentiation
206576_s_at	0.263	6.075	2.595	2.013e-02	0.438	-3.252	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	NM_001712	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
212878_s_at	-0.363	7.919	-2.595	2.015e-02	0.439	-3.253	KLC1	kinesin light chain 1	14	103165277, 103165277	AA284075	3831	14q32.3	Hs.20107 Hs.657678	31	microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle
206759_at	-0.221	3.702	-2.594	2.016e-02	0.439	-3.254	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	19	-7659643	NM_002002	2208	19p13.3	Hs.465778	71	receptor activity integrin binding binding sugar binding extracellular region plasma membrane integral to plasma membrane IgE binding positive regulation of nitric-oxide synthase activity positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase 2 biosynthetic process	Hematopoietic cell lineage
227776_at	0.539	5.642	2.594	2.018e-02	0.439	-3.254	ACER3	alkaline ceramidase 3	11	76249564	BF589251	55331	11q13.5	Hs.23862	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ceramide metabolic process membrane integral to membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	Sphingolipid metabolism
210039_s_at	-0.448	8.266	-2.594	2.018e-02	0.439	-3.255	PRKCQ	protein kinase C, theta	10	-6509110	L01087	5588	10p15	Hs.498570	112	nucleotide binding magnesium ion binding regulation of cell growth protein kinase C activity protein binding ATP binding intracellular protein amino acid phosphorylation membrane protein ectodomain proteolysis intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding	Vascular smooth muscle contraction Tight junction T cell receptor signaling pathway Adipocytokine signaling pathway
1553540_a_at	-0.359	6.009	-2.593	2.022e-02	0.439	-3.256	SLC29A2	solute carrier family 29 (nucleoside transporters), member 2	11	-65886567	NM_001532	3177	11q13	Hs.569017	26	nucleoside transmembrane transporter activity nucleus nucleolus plasma membrane integral to plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transport cell proliferation nucleoside transport
37996_s_at	0.459	6.701	2.592	2.027e-02	0.440	-3.258	DMPK	dystrophia myotonica-protein kinase	19	-50964815, -50964815	L08835	1760	19q13.3	Hs.631596	91	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein modification process protein amino acid phosphorylation regulation of heart contraction transferase activity
55692_at	0.239	7.074	2.591	2.030e-02	0.440	-3.259	ELMO2	engulfment and cell motility 2	20	-44428096	W22924	63916	20q13	Hs.210469	16	binding cytoplasm cytoskeleton phagocytosis apoptosis SH3 domain binding
227622_at	0.459	8.053	2.590	2.034e-02	0.440	-3.261	PCF11	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	11	82545784	AW118175	51585	11q13	Hs.128959	10	nuclear mRNA splicing, via spliceosome nucleus mRNA cleavage factor complex mRNA cleavage
209019_s_at	-0.308	10.140	-2.590	2.034e-02	0.440	-3.262	PINK1	PTEN induced putative kinase 1	1	20832534	AF316873	65018	1p36	Hs.389171	105	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding mitochondrion mitochondrial outer membrane protein amino acid phosphorylation response to stress protein kinase cascade membrane integral to membrane transferase activity positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion	Parkinson's disease
211452_x_at	0.337	8.109	2.590	2.035e-02	0.440	-3.262	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2	238200962, 238265545, 238265545	AF130054	9208	2q37.3	Hs.471779	16	DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity
227687_at	-0.399	5.901	-2.590	2.035e-02	0.440	-3.262	HYLS1	hydrolethalus syndrome 1	11	125258718, 125262164	AL523264	219844	11q24.2	Hs.585071	7	cytoplasm
205843_x_at	0.293	8.314	2.589	2.038e-02	0.440	-3.263	CRAT	carnitine acetyltransferase	9	-130896895, -130896893	NM_000755	1384	9q34.1	Hs.12068	10	carnitine O-acetyltransferase activity mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum lipid metabolic process fatty acid metabolic process transport acyltransferase activity energy derivation by oxidation of organic compounds membrane transferase activity
230679_at	0.318	3.507	2.589	2.038e-02	0.440	-3.263	DCAF10	DDB1 and CUL4 associated factor 10	9	37790789	AA976778	79269	9p13.2	Hs.118394	2
221692_s_at	-0.442	9.606	-2.589	2.038e-02	0.440	-3.263	MRPL34	mitochondrial ribosomal protein L34	19	17277476	AB049652	64981	19p13.1	Hs.515242	6	structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation translation regulator activity
220094_s_at	0.310	8.746	2.589	2.039e-02	0.440	-3.263	CCDC90A	coiled-coil domain containing 90A	6	-13898998	NM_022102	63933	6p24.3-p23	Hs.214043	3	mitochondrion membrane integral to membrane
215211_at	0.290	5.517	2.589	2.039e-02	0.440	-3.264	LOC730092	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene	16	-21715451	AF054994	730092	16p12.2	Hs.31290 Hs.348979 Hs.658149	4
209454_s_at	-0.393	6.300	-2.588	2.040e-02	0.440	-3.264	TEAD3	TEA domain family member 3	6	-35549351	AF142482	7005	6p21.2	Hs.485205	13	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter female pregnancy
215691_x_at	0.365	7.146	2.587	2.046e-02	0.441	-3.267	HSPB11	heat shock protein family B (small), member 11	1	-54159821	AV702994	51668	1p32.1-p33	Hs.525462 Hs.624686	9	response to stress cell adhesion
204363_at	-0.343	5.513	-2.587	2.047e-02	0.441	-3.267	F3	coagulation factor III (thromboplastin, tissue factor)	1	-94767319	NM_001993	2152	1p22-p21	Hs.62192	257	positive regulation of endothelial cell proliferation protease binding activation of plasma proteins involved in acute inflammatory response activation of blood coagulation via clotting cascade phospholipid binding extracellular space plasma membrane plasma membrane anti-apoptosis activation of caspase activity blood coagulation, extrinsic pathway positive regulation of platelet-derived growth factor receptor signaling pathway integral to membrane positive regulation of cell migration extracellular matrix intrinsic to external side of plasma membrane cell surface binding positive regulation of angiogenesis positive regulation of positive chemotaxis positive regulation of protein kinase B signaling cascade	Complement and coagulation cascades
227874_at	0.375	7.601	2.587	2.047e-02	0.441	-3.267	EMCN	endomucin	4	-101535522	AI635774	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
212372_at	0.681	7.144	2.586	2.048e-02	0.441	-3.267	MYH10	myosin, heavy chain 10, non-muscle	17	-8318254	AK026977	4628	17p13	Hs.16355	37	microfilament motor activity nucleotide binding cytokinesis after mitosis in utero embryonic development stress fiber neuron migration plasma membrane repair calmodulin binding ATP binding cytoplasm spindle plasma membrane cell cortex exocytosis substrate-bound cell migration, cell extension nuclear migration axon guidance brain development adult heart development biological_process cell proliferation regulation of cell shape myosin complex fourth ventricle development lateral ventricle development third ventricle development cerebellar Purkinje cell layer development actin cytoskeleton organization actin filament-based movement axon growth cone midbody actin-dependent ATPase activity neuron projection development neuromuscular junction cleavage furrow cell soma dendritic spine ADP binding neuromuscular process controlling balance actin filament binding cardiac myofibril assembly ventricular cardiac muscle cell development retina development in camera-type eye	Tight junction Regulation of actin cytoskeleton
1565329_at	0.379	2.450	2.586	2.048e-02	0.441	-3.268	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	2	75039282	AY034104	56655	2p12	Hs.469060	5	DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
212835_at	-0.529	6.466	-2.586	2.049e-02	0.441	-3.268	FAM175B	family with sequence similarity 175, member B	10	126480343	AA777641	23172	10q26.13	Hs.280695	10	protein binding polyubiquitin binding BRISC complex
1555314_at	0.245	3.178	2.586	2.051e-02	0.441	-3.269	WDR19	WD repeat domain 19	4	38860418	BC032578	57728	4p14	Hs.438482	8	protein binding intracellular protein transport vesicle-mediated transport
202459_s_at	0.217	4.693	2.585	2.052e-02	0.441	-3.269	LPIN2	lipin 2	18	-2906991	U55968	9663	18p11.31	Hs.132342	10	nucleus phosphatidate phosphatase activity
222287_at	-0.449	11.343	-2.585	2.053e-02	0.441	-3.269	TRDN	triadin	6	-123579181	AW969675	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
224966_s_at	-0.217	4.780	-2.585	2.053e-02	0.441	-3.270	DUS3L	dihydrouridine synthase 3-like (S. cerevisiae)	19	-5736154	AI857915	56931	19p13.3	Hs.284297	5	nucleic acid binding tRNA processing zinc ion binding oxidoreductase activity tRNA dihydrouridine synthase activity metal ion binding FAD binding oxidation reduction
1562703_at	0.252	3.895	2.585	2.054e-02	0.441	-3.270	LOC157381	hypothetical LOC157381	8	126023430	BC033393	157381	8q24.13	Hs.638933 Hs.651593	3
203588_s_at	-0.377	6.335	-2.585	2.055e-02	0.441	-3.270	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	BG034328	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
222235_s_at	-0.392	6.103	-2.584	2.056e-02	0.441	-3.271	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	10	42953939	AL139812	55454	10q11.21	Hs.657569	6	protein binding Golgi apparatus membrane integral to membrane transferase activity integral to Golgi membrane Golgi cisterna membrane metal ion binding glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Chondroitin sulfate biosynthesis Metabolic pathways
222919_at	-0.373	12.085	-2.584	2.056e-02	0.441	-3.271	TRDN	triadin	6	-123579181	AA192306	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
206469_x_at	0.234	6.145	2.584	2.057e-02	0.441	-3.271	AKR7A3	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	1	-19481643	NM_012067	22977	1p36.13	Hs.6980	6	aldo-keto reductase activity cytoplasm cytosol cellular aldehyde metabolic process electron carrier activity oxidoreductase activity oxidation reduction
201729_s_at	-0.230	7.560	-2.584	2.057e-02	0.441	-3.271	KIAA0100	KIAA0100	17	-23965584	NM_014680	9703	17q11.2	Hs.151761	5	extracellular region tricarboxylic acid cycle malate dehydrogenase (acceptor) activity
224505_s_at	-0.335	8.831	-2.584	2.059e-02	0.441	-3.272	PLCD4	phospholipase C, delta 4	2	219180875	BC006355	84812	2q35	Hs.632528	19	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding nucleus cytoplasm endoplasmic reticulum intracellular signaling cascade membrane lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system
225996_at	0.372	7.455	2.583	2.060e-02	0.441	-3.272	LONRF2	LON peptidase N-terminal domain and ring finger 2	2	-100256184	AV709727	164832	2q11.2	Hs.21380	4	ATP-dependent peptidase activity protein binding proteolysis zinc ion binding metal ion binding
203726_s_at	0.348	4.918	2.583	2.061e-02	0.441	-3.273	LAMA3	laminin, alpha 3	18	19523559, 19706981	NM_000227	3909	18q11.2	Hs.436367	49	receptor binding structural molecule activity extracellular region basement membrane laminin-1 complex epidermis development regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
209124_at	0.316	6.129	2.583	2.061e-02	0.441	-3.273	MYD88	myeloid differentiation primary response gene (88)	3	38154972	U70451	4615	3p22	Hs.82116	98	response to molecule of fungal origin MyD88-dependent toll-like receptor signaling pathway transmembrane receptor activity Toll binding death receptor binding protein binding cytoplasm inflammatory response Toll signaling pathway response to virus immunoglobulin mediated immune response cytokine-mediated signaling pathway intrinsic to membrane lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide positive regulation of tumor necrosis factor production regulation of cell proliferation positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of chemokine biosynthetic process innate immune response type I interferon biosynthetic process positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade positive regulation of smooth muscle cell proliferation positive regulation of NF-kappaB transcription factor activity	Apoptosis Toll-like receptor signaling pathway
223436_s_at	0.631	8.773	2.583	2.062e-02	0.441	-3.273	TRPT1	tRNA phosphotransferase 1	11	-63747847, -63747847	BC005133	83707	11q13.1	Hs.326586	6	tRNA 2'-phosphotransferase activity tRNA splicing, via endonucleolytic cleavage and ligation transferase activity, transferring phosphorus-containing groups
206355_at	-0.968	5.808	-2.582	2.067e-02	0.442	-3.275	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18	11679135, 11741561	R20102	2774	18p11.22-p11.21	Hs.136295	16	nucleotide binding GTPase activity signal transducer activity GTP binding signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding	Calcium signaling pathway Olfactory transduction
214242_at	0.219	4.748	2.582	2.068e-02	0.442	-3.276	MAN1A2	mannosidase, alpha, class 1A, member 2	1	117711607	AI189305	10905	1p13	Hs.435938	25	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding membrane fraction Golgi apparatus N-glycan processing metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds	N-Glycan biosynthesis Metabolic pathways
1554258_a_at	-0.289	5.286	-2.580	2.073e-02	0.443	-3.278	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	8	67096344	AF368276	85479	8q13.1	Hs.491885	3	protein folding membrane heat shock protein binding unfolded protein binding
229393_at	0.337	4.659	2.580	2.074e-02	0.443	-3.279	L3MBTL3	l(3)mbt-like 3 (Drosophila)	6	130381426	AA088346	84456	6q23	Hs.658051	8	molecular_function nucleus regulation of transcription
205163_at	-0.596	13.398	-2.579	2.077e-02	0.443	-3.280	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	16	30293623	NM_013292	29895	16p11.2	Hs.50889	5	motor activity calcium ion binding muscle myosin complex skeletal muscle tissue development structural constituent of muscle myosin complex	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
203369_x_at	-0.352	7.046	-2.579	2.077e-02	0.443	-3.280	PDLIM7	PDZ and LIM domain 7 (enigma)	5	-176849852, -176843000	AI825846	9260	5q35.3	Hs.533040	22	ossification protein binding cytoplasm cytoskeleton receptor-mediated endocytosis multicellular organismal development zinc ion binding cell differentiation metal ion binding
220901_at	-0.467	5.578	-2.578	2.081e-02	0.443	-3.281	GPR157	G protein-coupled receptor 157	1	-9087062	NM_024980	80045	1p36.23	Hs.632367	5	G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane
218397_at	0.342	6.817	2.578	2.082e-02	0.443	-3.282	FANCL	Fanconi anemia, complementation group L	2	-58239881	NM_018062	55120	2p16.1	Hs.631890	19	protein binding nucleus cytoplasm DNA repair response to DNA damage stimulus zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
235216_at	-0.400	3.166	-2.578	2.084e-02	0.443	-3.283	ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)	18	-17363259	BG532121	114799	18q11.2	Hs.464733	8	damaged DNA binding DNA-directed DNA polymerase activity nucleus DNA repair cell cycle zinc ion binding acyltransferase activity transferase activity metal ion binding
218937_at	0.303	5.265	2.577	2.085e-02	0.444	-3.283	ZNF434	zinc finger protein 434	16	-3372085	NM_017810	54925	16p13.3	Hs.592078	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
232905_at	0.371	4.405	2.577	2.086e-02	0.444	-3.284	GTF2H5	general transcription factor IIH, polypeptide 5	6	158509366	AK024874	404672	6q25.3	Hs.356224	11	DNA binding nucleus nucleotide-excision repair response to DNA damage stimulus regulation of transcription	Nucleotide excision repair
211536_x_at	-0.235	5.661	-2.577	2.086e-02	0.444	-3.284	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AB009358	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
225215_s_at	-0.302	8.333	-2.576	2.089e-02	0.444	-3.285	MTRF1L	mitochondrial translational release factor 1-like	6	-153350092	BF665339	54516	6q25-q26	Hs.225836 Hs.304818	9	cytoplasm mitochondrion translational termination translation release factor activity, codon specific
200732_s_at	-0.460	10.872	-2.576	2.089e-02	0.444	-3.285	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	AL578310	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
215028_at	0.466	4.078	2.576	2.092e-02	0.444	-3.286	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	5	-115807149	AB002438	57556	5q23.1	Hs.156967	11	receptor activity protein binding apoptosis cytoskeleton organization cell surface receptor linked signal transduction multicellular organismal development nervous system development axon guidance organ morphogenesis membrane integral to membrane cell differentiation axon	Axon guidance
214258_x_at	-0.268	6.675	-2.575	2.095e-02	0.444	-3.287	KAT5	K(lysine) acetyltransferase 5	11	65236064	AA886971	10524	11q13	Hs.397010	88	chromatin chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding nucleus nucleolus cytoplasm double-strand break repair chromatin assembly or disassembly DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator zinc ion binding acyltransferase activity chromatin modification histone acetylation transferase activity androgen receptor signaling pathway Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding perinuclear region of cytoplasm androgen receptor binding
212566_at	-0.285	10.545	-2.575	2.095e-02	0.444	-3.288	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AL523310	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
211665_s_at	-0.677	5.476	-2.575	2.097e-02	0.444	-3.288	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	L20686	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
205706_s_at	-0.383	5.413	-2.574	2.097e-02	0.444	-3.288	ANKRD26	ankyrin repeat domain 26	10	-27333050	NM_014915	22852	10pter-q22.1	Hs.361041	8
218185_s_at	-0.407	7.440	-2.574	2.100e-02	0.444	-3.289	ARMC1	armadillo repeat containing 1	8	-66677627	NM_018120	55156	8q13.1	Hs.269542	3	binding metal ion transport metal ion binding
227388_at	-0.427	7.954	-2.574	2.100e-02	0.444	-3.289	TUSC1	tumor suppressor candidate 1	9	-25666386	AA479016	286319	9p21.2	Hs.26268 Hs.606014	2
204777_s_at	0.238	5.155	2.574	2.100e-02	0.444	-3.289	MAL	mal, T-cell differentiation protein	2	95055205	NM_002371	4118	2cen-q13	Hs.80395	28	membrane raft polarization endosome endoplasmic reticulum integral to plasma membrane induction of apoptosis central nervous system development lipid binding channel activity membrane apical plasma membrane apoptotic protease activator activity structural constituent of myelin sheath cell differentiation myelination myelination membrane raft apical protein localization
230404_at	0.233	4.668	2.574	2.101e-02	0.444	-3.290	FLJ44606	glutaredoxin-like protein YDR286C homolog	5		AI418538	401207	5q23.2	Hs.49573	1	transport electron transport chain
223532_at	0.296	5.944	2.574	2.101e-02	0.444	-3.290	ANKRD39	ankyrin repeat domain 39	2	-96877450	AF151034	51239	2q11.2	Hs.709507	6
213789_at	0.217	5.459	2.573	2.103e-02	0.445	-3.291	EBP	emopamil binding protein (sterol isomerase)	X	48265107	N58493	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
210284_s_at	-0.377	6.650	-2.572	2.108e-02	0.445	-3.293	MAP3K7IP2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	6	149680755	AF241230	23118	6q25.1-q25.3	Hs.269775	39	protein binding intracellular cytoplasm cytosol cytosol zinc ion binding membrane positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway Toll-like receptor signaling pathway
219127_at	0.275	4.213	2.571	2.112e-02	0.446	-3.294	ATAD4	ATPase family, AAA domain containing 4	17	-43384332	NM_024320	79170	17q21.32	Hs.368260	1
206966_s_at	0.276	5.446	2.571	2.112e-02	0.446	-3.295	KLF12	Kruppel-like factor 12	13	-73158149	NM_016285	11278	13q22	Hs.373857 Hs.592500	17	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription corepressor activity intracellular nucleus zinc ion binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
220416_at	0.276	2.895	2.570	2.116e-02	0.446	-3.296	ATP8B4	ATPase, class I, type 8B, member 4	15	-47937726	NM_024837	79895	15q21.2	Hs.511311	7	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
204781_s_at	-0.295	4.273	-2.569	2.118e-02	0.446	-3.297	FAS	Fas (TNF receptor superfamily, member 6)	10	90740267, 90740267	NM_000043	355	10q24.1	Hs.244139	589	immunoglobulin production renal system process transmembrane receptor activity extracellular region soluble fraction cytosol plasma membrane plasma membrane protein complex assembly anti-apoptosis activation-induced cell death of T cells inflammatory cell apoptosis transformed cell apoptosis immune response signal transduction induction of apoptosis via death domain receptors activation of pro-apoptotic gene products response to toxin external side of plasma membrane gene expression positive regulation of necrotic cell death integral to membrane B cell mediated immunity kinase binding death-inducing signaling complex identical protein binding negative thymic T cell selection regulation of lymphocyte differentiation regulation of myeloid cell differentiation spleen development negative regulation of B cell activation protein homooligomerization response to glucocorticoid stimulus response to protein stimulus	MAPK signaling pathway Cytokine-cytokine receptor interaction p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Type I diabetes mellitus Alzheimer's disease Pathways in cancer Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
211653_x_at	1.089	9.225	2.569	2.119e-02	0.446	-3.297	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	10	-5021964	M33376	1646	10p15-p14	Hs.460260 Hs.567256	35	cytoplasm lipid metabolic process prostaglandin metabolic process digestion steroid metabolic process oxidoreductase activity carboxylic acid binding bile acid binding 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity oxidation reduction	Metabolism of xenobiotics by cytochrome P450
229271_x_at	-0.288	1.889	-2.569	2.121e-02	0.446	-3.298	COL11A1	collagen, type XI, alpha 1	1	-103114610	BG028597	1301	1p21	Hs.523446	31	extracellular matrix structural constituent extracellular region collagen collagen type XI collagen type XI cell adhesion visual perception collagen fibril organization protein binding, bridging extracellular matrix binding detection of mechanical stimulus involved in sensory perception of sound	Focal adhesion ECM-receptor interaction
202115_s_at	-0.168	6.997	-2.568	2.125e-02	0.447	-3.300	NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	1	-869445	NM_015658	26155	1p36.33	Hs.405987	23	protein binding nucleus nucleolus
212219_at	-0.243	8.217	-2.568	2.126e-02	0.447	-3.300	PSME4	proteasome (prosome, macropain) activator subunit 4	2	-53944707	D38521	23198	2p16.2	Hs.413801	30	binding nucleus cytosol multicellular organismal development spermatogenesis nuclear speck cell differentiation protein complex	Proteasome
1561928_s_at	0.223	5.156	2.567	2.129e-02	0.447	-3.301	C3orf16	chromosome 3 open reading frame 16	3	-150961581	AK027233	389161	3q25.1	Hs.665988	3
222899_at	0.236	4.932	2.566	2.131e-02	0.447	-3.302	ITGA11	integrin, alpha 11	15	-66381095	AF109681	22801	15q23	Hs.436416	12	magnesium ion binding receptor activity calcium ion binding collagen binding substrate-bound cell migration cell adhesion cell-matrix adhesion integrin-mediated signaling pathway muscle organ development integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212268_at	-0.420	6.390	-2.566	2.132e-02	0.447	-3.303	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	6	-2778732	NM_030666	1992	6p25	Hs.381167	18	serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity
240449_at	-0.406	5.332	-2.566	2.133e-02	0.447	-3.303	ZNF341	zinc finger protein 341	20	31783468	AW204518	84905	20q11.22	Hs.516989	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212239_at	0.508	7.454	2.566	2.133e-02	0.447	-3.303	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	5	67558217, 67620007, 67622250	AI680192	5295	5q13.1	Hs.132225 Hs.604502	321	negative regulation of cell-matrix adhesion insulin receptor binding insulin-like growth factor receptor binding phosphatidylinositol binding intracellular cytosol cytosol 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex protein amino acid phosphorylation signal transduction insulin receptor signaling pathway phosphoinositide 3-kinase cascade membrane protein phosphatase binding B cell differentiation positive regulation of cell migration phosphoinositide 3-kinase regulator activity negative regulation of apoptosis ErbB-3 class receptor binding insulin binding insulin receptor substrate binding interspecies interaction between organisms negative regulation of osteoclast differentiation positive regulation of glucose import phosphoinositide phosphorylation insulin-like growth factor receptor signaling pathway growth hormone receptor signaling pathway regulation of establishment of protein localization	ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
220199_s_at	-0.471	5.831	-2.566	2.134e-02	0.447	-3.304	AIDA	axin interactor, dorsalization associated	1	-220907977	NM_022831	64853	1q41	Hs.156625 Hs.534965 Hs.707666	6	protein binding cellular_component multicellular organismal development dorsal/ventral pattern formation regulation of protein homodimerization activity negative regulation of JNK cascade
1556136_at	-1.587	6.925	-2.565	2.136e-02	0.447	-3.304	MYLK4	myosin light chain kinase family, member 4	6	-2608861	BU675945	340156	6p25.2	Hs.127830	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
226251_at	-0.330	5.926	-2.565	2.136e-02	0.447	-3.304	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	AW295549	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
231178_at	0.572	5.558	2.565	2.138e-02	0.447	-3.305	SPATA4	spermatogenesis associated 4	4	-177342718	BG150360	132851	4q34.2	Hs.481235	4	molecular_function cellular_component cytoplasm apoptosis spermatogenesis
1570210_x_at	0.302	6.102	2.565	2.139e-02	0.447	-3.306	SAPS2	SAPS domain family, member 2	22	49128625	BC022346	9701	22q13.33	Hs.449098 Hs.710221	8	protein binding cytoplasm
219014_at	0.425	4.372	2.565	2.139e-02	0.447	-3.306	PLAC8	placenta-specific 8	4	-84234330, -84230234, -84230234	NM_016619	51316	4q21.22	Hs.546392	5
205321_at	-0.632	5.896	-2.564	2.140e-02	0.447	-3.306	EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	X	23982985	NM_001415	1968	Xp22.2-p22.1	Hs.539684	21	nucleotide binding translation initiation factor activity GTPase activity protein binding GTP binding cytosol translational initiation
212617_at	0.211	4.980	2.564	2.143e-02	0.448	-3.307	ZNF609	zinc finger protein 609	15	62578671	AB002293	23060	15q22.31	Hs.595451 Hs.696256 Hs.719276	7	intracellular nucleus zinc ion binding metal ion binding
218399_s_at	0.235	5.381	2.563	2.144e-02	0.448	-3.308	CDCA4	cell division cycle associated 4	14	-104546954	NM_017955	55038	14q32.33	Hs.34045 Hs.532504 Hs.715701	9	nucleus
1555307_at	-0.192	2.240	-2.563	2.145e-02	0.448	-3.308	TTF2	transcription termination factor, RNA polymerase II	1	117404471	BC030058	8458	1p22	Hs.486818	12	nucleotide binding DNA binding RNA polymerase II transcription termination factor activity helicase activity ATP binding nucleus spliceosomal complex cytoplasm transcription termination mRNA processing transcription elongation factor complex ATP-dependent helicase activity DNA-dependent ATPase activity zinc ion binding RNA splicing hydrolase activity regulation of transcription
227998_at	0.366	7.830	2.563	2.147e-02	0.448	-3.309	S100A16	S100 calcium binding protein A16	1	-151845990	AA045184	140576	1q21	Hs.515714	8	calcium ion binding nucleus cytoplasm protein homodimerization activity response to calcium ion
1555173_at	0.219	2.711	2.562	2.150e-02	0.448	-3.310	STX19	syntaxin 19	3	-95215904	BC034696	415117	3q11	Hs.679768	2	SNAP receptor activity intracellular protein transport membrane vesicle-mediated transport	SNARE interactions in vesicular transport
201899_s_at	-0.243	9.213	-2.561	2.153e-02	0.449	-3.311	UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	X	118592526, 118598325	NM_003336	7319	Xq24-q25	Hs.379466	16	nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination	Ubiquitin mediated proteolysis
208076_at	0.271	3.011	2.561	2.155e-02	0.449	-3.312	HIST1H4D	histone cluster 1, H4d	6	-26296916	NM_003539	8360	6p21.3	Hs.248179	10		Systemic lupus erythematosus
215040_at	0.306	6.661	2.561	2.155e-02	0.449	-3.312	RNASEH2B	ribonuclease H2, subunit B	13	50381892, 50381892	AL049218	79621	13q14.3	Hs.306291	13	nucleus	DNA replication
218773_s_at	0.224	10.273	2.560	2.158e-02	0.449	-3.313	MSRB2	methionine sulfoxide reductase B2	10	23424432	NM_012228	22921	10p12	Hs.461420	14	protein-methionine-R-oxide reductase activity transcription factor activity mitochondrion peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity protein repair metal ion binding oxidation reduction
225447_at	-0.596	7.547	-2.560	2.159e-02	0.449	-3.314	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	2	157000210, 157001145	AA613031	2820	2q24.1	Hs.512382	20	glycerol-3-phosphate dehydrogenase activity calcium ion binding mitochondrion mitochondrial inner membrane glycerol-3-phosphate metabolic process gluconeogenesis glycerol-3-phosphate dehydrogenase complex oxidoreductase activity oxidation reduction	Glycerophospholipid metabolism
221322_at	0.208	2.626	2.559	2.162e-02	0.450	-3.315	NPVF	neuropeptide VF precursor	7	-25230715	NM_022150	64111	7p21-p15	Hs.60473	8	G-protein coupled receptor activity protein binding extracellular region neuropeptide signaling pathway membrane
1554808_at	-0.255	3.564	-2.558	2.166e-02	0.450	-3.317	ACP1	acid phosphatase 1, soluble	2	254868, 254868	BC020699	52	2p25	Hs.558296	69	acid phosphatase activity non-membrane spanning protein tyrosine phosphatase activity soluble fraction cytoplasm protein amino acid dephosphorylation hydrolase activity identical protein binding	gamma-Hexachlorocyclohexane degradation Riboflavin metabolism Adherens junction
224756_s_at	-0.356	7.144	-2.558	2.168e-02	0.450	-3.318	BAT5	HLA-B associated transcript 5	6	-31762714, -3100861, -2902325	AL578487	7920	6p21.3	Hs.388188	14	protein binding cytosol defense response response to unfolded protein response to nutrient membrane integral to membrane protein complex NF-kappaB binding
230645_at	0.313	7.675	2.557	2.171e-02	0.451	-3.319	FRMD3	FERM domain containing 3	9	-85052126	BF110588	257019	9q21.32	Hs.709357	7	binding cytoplasm cytoskeleton cytoskeletal protein binding membrane integral to membrane extrinsic to membrane
218120_s_at	0.328	6.908	2.556	2.174e-02	0.451	-3.320	HMOX2	heme oxygenase (decycling) 2	16	4464719, 4466341, 4485859	D21243	3163	16p13.3	Hs.284279	32	response to hypoxia heme oxygenase (decyclizing) activity iron ion binding protein binding endoplasmic reticulum microsome plasma membrane heme oxidation electron carrier activity oxidoreductase activity metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
226922_at	0.327	6.751	2.556	2.175e-02	0.451	-3.320	RANBP2	RAN binding protein 2	2	108702368	BF215302	5903	2q12.3	Hs.199561 Hs.715056	61	peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport
209947_at	0.254	6.629	2.556	2.175e-02	0.451	-3.320	UBAP2L	ubiquitin associated protein 2-like	1	152459278, 152459948	BC003170	9898	1q21.3	Hs.490551	12	protein binding
215886_x_at	-0.183	4.869	-2.556	2.177e-02	0.451	-3.321	USP12	ubiquitin specific peptidase 12	13	-26540437	AF022790	219333	13q12.13	Hs.42400	6	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding cellular_component protein modification process ubiquitin-dependent protein catabolic process peptidase activity protein deubiquitination
229994_at	0.382	5.018	2.556	2.178e-02	0.451	-3.321	NFIA	nuclear factor I/A	1	61315533, 61320121, 61320567	R45950	4774	1p31.3-p31.2	Hs.594180 Hs.710546	20	transcription factor activity intracellular nucleus nucleus cytoplasm plasma membrane DNA replication regulation of transcription, DNA-dependent transcription factor binding viral genome replication
212686_at	0.688	4.046	2.554	2.183e-02	0.452	-3.323	PPM1H	protein phosphatase 1H (PP2C domain containing)	12	-61324030	AB032983	57460	12q14.1-q14.2	Hs.435479	5	phosphoprotein phosphatase activity hydrolase activity
238018_at	-0.198	2.506	-2.554	2.184e-02	0.452	-3.324	FAM150B	family with sequence similarity 150, member B	2	-269560	BF449053	285016	2p25.3	Hs.355207	2	extracellular region
221688_s_at	-0.337	8.008	-2.554	2.184e-02	0.452	-3.324	IMP3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)	15	-73718490	AL136913	55272	15q24	Hs.513043	21	protein binding intracellular nucleus nucleolus rRNA processing rRNA binding ribonucleoprotein complex
229850_at	0.354	4.924	2.554	2.184e-02	0.452	-3.324	KDSR	3-ketodihydrosphingosine reductase	18	-59145950	N30152	2531	18q21.3	Hs.74050	12	binding extracellular space endoplasmic reticulum membrane integral to membrane oxidoreductase activity 3-dehydrosphinganine reductase activity oxidation reduction	Sphingolipid metabolism Metabolic pathways
229732_at	0.388	4.007	2.554	2.185e-02	0.452	-3.324	ZNF823	zinc finger protein 823	19	-11693079	AI417785	55552	19p13.2	Hs.142167	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208680_at	-0.338	10.706	-2.554	2.186e-02	0.452	-3.325	PRDX1	peroxiredoxin 1	1	-45749293	L19184	5052	1p34.1	Hs.180909	62	skeletal system development protein binding nucleus cytoplasm mitochondrion cell proliferation oxidoreductase activity melanosome hydrogen peroxide catabolic process cell redox homeostasis peroxiredoxin activity oxidation reduction
242492_at	0.289	4.835	2.553	2.188e-02	0.452	-3.326	CLNS1A	chloride channel, nucleotide-sensitive, 1A	11	-77004844	AA412065	1207	11q13.5-q14	Hs.430733 Hs.598033	24	spliceosomal snRNP biogenesis nucleus cytoplasm cytosol cytoskeleton plasma membrane transport chloride transport cell volume homeostasis blood circulation
201926_s_at	-0.417	7.311	-2.553	2.189e-02	0.452	-3.326	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	1	205561439	BC001288	1604	1q32	Hs.126517	118	soluble fraction plasma membrane integral to plasma membrane complement activation, classical pathway elevation of cytosolic calcium ion concentration anchored to membrane innate immune response membrane raft respiratory burst	Complement and coagulation cascades Hematopoietic cell lineage
212446_s_at	0.618	5.692	2.553	2.190e-02	0.452	-3.326	LASS6	LAG1 homolog, ceramide synthase 6	2	169021080	AI658534	253782	2q24.3	Hs.506829 Hs.718403	5	transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding ceramide biosynthetic process sphingosine N-acyltransferase activity
223301_s_at	0.290	6.164	2.552	2.193e-02	0.452	-3.327	CCDC82	coiled-coil domain containing 82	11	-95725576	AF245436	79780	11q21	Hs.525088	9	protein binding
220397_at	-0.245	3.400	-2.552	2.193e-02	0.452	-3.328	MDM1	Mdm1 nuclear protein homolog (mouse)	12	-67005051, -66974612	NM_020128	56890	12q15	Hs.655702	6	nucleus
201476_s_at	-0.358	6.428	-2.552	2.195e-02	0.452	-3.328	RRM1	ribonucleotide reductase M1	11	4072499	AI692974	6240	11p15.5	Hs.445705	44	ribonucleoside-diphosphate reductase activity protein binding ATP binding cytoplasm cytosol ribonucleoside-diphosphate reductase complex DNA replication deoxyribonucleotide biosynthetic process oxidoreductase activity purine nucleotide binding protein oligomerization oxidation reduction	Purine metabolism Pyrimidine metabolism Glutathione metabolism Metabolic pathways
219456_s_at	0.203	3.966	2.551	2.197e-02	0.452	-3.329	RIN3	Ras and Rab interactor 3	14	92049877	AW027923	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
226635_at	-0.444	7.121	-2.551	2.199e-02	0.452	-3.330	LOC401504	hypothetical gene supported by AK091718	9		BG170478	401504	9p13.2	Hs.446271	2
211982_x_at	0.196	6.856	2.550	2.201e-02	0.452	-3.331	XPO6	exportin 6	16	-28016816	AL546600	23214	16p11.2	Hs.460468	11	protein import into nucleus, docking protein binding nucleus nuclear pore cytoplasm protein export from nucleus intracellular protein transport protein transporter activity
227374_at	0.255	6.107	2.550	2.201e-02	0.452	-3.331	EARS2	glutamyl-tRNA synthetase 2, mitochondrial (putative)	16	-23440834	AA833716	124454	16p12.2	Hs.620541	6	nucleotide binding RNA binding glutamate-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix glutamyl-tRNA aminoacylation ligase activity	Porphyrin and chlorophyll metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways
233836_at	0.275	6.106	2.550	2.202e-02	0.452	-3.331	TNRC6A	trinucleotide repeat containing 6A	16	24648549	AK025277	27327	16p11.2	Hs.655057	28	nucleotide binding cytoplasmic mRNA processing body RNA binding cytoplasm regulation of translation gene silencing by RNA micro-ribonucleoprotein complex gene silencing by miRNA, negative regulation of translation
1563290_at	0.218	5.303	2.549	2.205e-02	0.452	-3.332	DNAH3	dynein, axonemal, heavy chain 3	16	-20851976	Z83805	55567	16p12.3	Hs.526500	7	nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme	Huntington's disease
1565947_a_at	0.233	3.298	2.549	2.205e-02	0.452	-3.332	CHML	choroideremia-like (Rab escort protein 2)	1	-239858789	AJ293392	1122	1q42-qter	Hs.654545	17	Rab geranylgeranyltransferase activity GTPase activator activity Rab-protein geranylgeranyltransferase complex intracellular protein transport visual perception regulation of GTPase activity
203149_at	-0.237	5.774	-2.549	2.206e-02	0.452	-3.333	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	19	50041232, 50041232	NM_002856	5819	19q13.2	Hs.655455	38	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of immunoglobulin mediated immune response plasma membrane cell-cell junction zonula adherens cell adhesion homophilic cell adhesion spermatid development cell surface coreceptor activity integral to membrane viral envelope fusion with host membrane positive regulation of mast cell activation susceptibility to natural killer cell mediated cytotoxicity virion attachment, binding of host cell surface coreceptor cell adhesion molecule binding adhesion to symbiont susceptibility to T cell mediated cytotoxicity	Cell adhesion molecules (CAMs) Adherens junction
209067_s_at	-0.307	9.175	-2.549	2.206e-02	0.452	-3.333	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	D89092	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
204140_at	0.339	5.469	2.549	2.206e-02	0.452	-3.333	TPST1	tyrosylprotein sulfotransferase 1	7	65307693	NM_003596	8460	7q11.21	Hs.421194	17	membrane fraction Golgi apparatus peptidyl-tyrosine sulfation inflammatory response protein-tyrosine sulfotransferase activity membrane integral to membrane transferase activity
241698_at	-0.206	3.005	-2.549	2.207e-02	0.452	-3.333	RFTN2	raftlin family member 2	2	-198143771	AI206317	130132	2q33.1	Hs.591615	4	plasma membrane
217952_x_at	-0.417	7.112	-2.549	2.207e-02	0.452	-3.333	PHF3	PHD finger protein 3	6	64414389	BF430956	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
241729_at	-0.239	3.747	-2.549	2.208e-02	0.452	-3.334	DOK6	docking protein 6	18	65219270	AW173080	220164	18q22.2	Hs.278285	4	insulin receptor binding
219634_at	-0.227	4.306	-2.548	2.209e-02	0.452	-3.334	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	12	103374907	NM_018413	50515	12q	Hs.17569	11	N-acetylgalactosamine 4-O-sulfotransferase activity chondrocyte development Golgi apparatus respiratory gaseous exchange post-embryonic development membrane integral to membrane carbohydrate biosynthetic process transferase activity chondroitin sulfate biosynthetic process negative regulation of transforming growth factor beta receptor signaling pathway polysaccharide localization tail morphogenesis regulation of cell proliferation embryonic digit morphogenesis negative regulation of apoptosis chondroitin 4-sulfotransferase activity developmental growth embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis cartilage development	Chondroitin sulfate biosynthesis Sulfur metabolism
218757_s_at	-0.360	7.156	-2.548	2.209e-02	0.452	-3.334	UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	X	-118852016	NM_023010	65109	Xq25-q26	Hs.103832	26	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome RNA binding nucleocytoplasmic transporter activity protein binding nucleus cytoplasm transport mRNA transport
209908_s_at	-0.262	3.082	-2.548	2.209e-02	0.452	-3.334	TGFB2	transforming growth factor, beta 2	1	216586013	BF061658	7042	1q41	Hs.133379	112	cell morphogenesis skeletal system development cartilage condensation angiogenesis beta-amyloid binding blood vessel development eye development response to hypoxia blood vessel remodeling receptor signaling protein serine/threonine kinase activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding cytokine activity extracellular region extracellular region extracellular region extracellular space induction of apoptosis activation-induced cell death of T cells cell cycle arrest transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation cell-cell signaling axon guidance salivary gland morphogenesis growth factor activity cell death positive regulation of cell proliferation glial cell migration embryonic development positive regulation of epithelial cell migration negative regulation of alkaline phosphatase activity positive regulation of epithelial to mesenchymal transition positive regulation of phosphoinositide 3-kinase cascade menstrual cycle phase hemopoiesis collagen fibril organization positive regulation of cell growth negative regulation of cell growth axon neutrophil chemotaxis neutrophil chemotaxis extracellular matrix hair follicle morphogenesis platelet alpha granule lumen activation of protein kinase activity response to progesterone stimulus positive regulation of stress-activated MAPK cascade regulation of transforming growth factor-beta2 production positive regulation of cell adhesion mediated by integrin wound healing dopamine biosynthetic process odontogenesis protein homodimerization activity cell soma positive regulation of neuron apoptosis cell-cell junction organization positive regulation of integrin biosynthetic process positive regulation of ossification positive regulation of cell cycle positive regulation of heart contraction protein heterodimerization activity somatic stem cell division neuron fate commitment neuron development generation of neurons negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive regulation of protein secretion negative regulation of immune response positive regulation of immune response positive regulation of catagen positive regulation of cardioblast differentiation cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition pathway-restricted SMAD protein phosphorylation	MAPK signaling pathway Cytokine-cytokine receptor interaction Cell cycle TGF-beta signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hypertrophic cardiomyopathy (HCM)
219338_s_at	0.291	3.815	2.548	2.210e-02	0.452	-3.334	LRRC49	leucine rich repeat containing 49	15	68972040	NM_017691	54839	15q23	Hs.12692	7	protein binding cytoplasm cytoskeleton microtubule
203460_s_at	-0.321	5.881	-2.548	2.210e-02	0.452	-3.334	PSEN1	presenilin 1	14	72672895	NM_007318	5663	14q24.3	Hs.3260	386	kinetochore endopeptidase activity membrane fraction integral to nuclear inner membrane nuclear outer membrane mitochondrion endoplasmic reticulum Golgi apparatus integral to plasma membrane membrane protein ectodomain proteolysis apoptosis anti-apoptosis chromosome segregation Notch receptor processing intracellular signaling cascade beta-catenin binding cell death peptidase activity cell surface membrane cell-cell adhesion protein processing PDZ domain binding endoplasmic reticulum calcium ion homeostasis regulation of phosphorylation amyloid precursor protein catabolic process positive regulation of catalytic activity	Wnt signaling pathway Notch signaling pathway Neurotrophin signaling pathway Alzheimer's disease
200608_s_at	-0.319	9.185	-2.548	2.211e-02	0.452	-3.335	RAD21	RAD21 homolog (S. pombe)	8	-117927354	NM_006265	5885	8q24	Hs.81848	33	nuclear chromosome protein binding nucleus double-strand break repair apoptosis response to DNA damage stimulus cell cycle chromosome segregation mitosis reciprocal meiotic recombination cell division	Cell cycle
230069_at	0.343	5.230	2.548	2.211e-02	0.452	-3.335	SFXN1	sideroflexin 1	5	174838119	BF593817	94081		Hs.369440	18	iron ion binding protein binding mitochondrion mitochondrial inner membrane cation transport iron ion transport cation transmembrane transporter activity membrane integral to membrane erythrocyte differentiation
1559661_at	-0.336	3.220	-2.548	2.211e-02	0.452	-3.335	ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)	4	183482130	AF195420	55714	4q35.1	Hs.130438	7	signal transduction membrane integral to membrane
206833_s_at	-0.406	10.363	-2.548	2.212e-02	0.452	-3.335	ACYP2	acylphosphatase 2, muscle type	2	54195913	NM_001108	98	2p16.2	Hs.516173 Hs.642983	16	acylphosphatase activity phosphate metabolic process hydrolase activity	Pyruvate metabolism Benzoate degradation via CoA ligation
205337_at	0.240	2.805	2.547	2.214e-02	0.452	-3.336	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	AL139318	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
209904_at	0.315	13.411	2.547	2.216e-02	0.452	-3.337	TNNC1	troponin C type 1 (slow)	3	-52460147	AF020769	7134	3p21.3-p14.3	Hs.118845	48	calcium ion binding troponin complex regulation of muscle contraction troponin I binding troponin T binding regulation of muscle filament sliding speed protein homodimerization activity regulation of ATPase activity calcium-dependent protein binding actin filament binding ventricular cardiac muscle morphogenesis cardiac muscle contraction	Calcium signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
223077_at	0.339	4.823	2.547	2.217e-02	0.452	-3.337	TMOD3	tropomodulin 3 (ubiquitous)	15	49909180	AW576360	29766	15q21.1-q21.2	Hs.4998	9	actin binding tropomyosin binding cytoplasm cytoskeleton
203974_at	-0.461	8.270	-2.546	2.218e-02	0.452	-3.337	HDHD1A	haloacid dehalogenase-like hydrolase domain containing 1A	X	-6976960	NM_012080	8226	Xp22.32	Hs.185910	8	catalytic activity cellular_component metabolic process
225282_at	0.262	5.344	2.546	2.219e-02	0.452	-3.338	SMAP2	small ArfGAP2	1	40612314	AL137764	64744	1p35.3-p34.1	Hs.15200	4	cytoplasm ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding	Endocytosis
227569_at	-0.360	6.493	-2.546	2.221e-02	0.452	-3.339	LNX2	ligand of numb-protein X 2	13	-27018049	AU151331	222484	13q12.2	Hs.132359	6	protein binding zinc ion binding PDZ domain binding metal ion binding protein homooligomerization
231157_at	-0.359	5.922	-2.546	2.221e-02	0.452	-3.339	TTLL11	tubulin tyrosine ligase-like family, member 11	9	-123791010, -123624025	BE856668	158135	9q33.2	Hs.640663 Hs.644262	5	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process ligase activity
224160_s_at	-0.360	6.763	-2.545	2.222e-02	0.452	-3.339	ACAD9	acyl-Coenzyme A dehydrogenase family, member 9	3	130081022	BC001817	28976	3q21.3	Hs.567482	12	acyl-CoA dehydrogenase activity mitochondrion electron carrier activity FAD binding oxidation reduction	Geraniol degradation 1- and 2-Methylnaphthalene degradation
201351_s_at	-0.355	8.669	-2.544	2.227e-02	0.452	-3.341	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AF070656	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
218097_s_at	0.221	9.332	2.544	2.230e-02	0.453	-3.342	CUEDC2	CUE domain containing 2	10	-104172991	NM_024040	79004	10q24.32	Hs.500874	6	protein binding nucleus cytoplasm modification-dependent protein catabolic process
217868_s_at	-0.216	8.863	-2.544	2.231e-02	0.453	-3.342	METTL9	methyltransferase like 9	16	21518356	NM_016025	51108	16p13-p12	Hs.279583	6
203771_s_at	0.359	6.944	2.542	2.239e-02	0.454	-3.346	BLVRA	biliverdin reductase A	7	43764796	AA740186	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
202074_s_at	-0.396	11.092	-2.541	2.240e-02	0.454	-3.346	OPTN	optineurin	10	13182087	NM_021980	10133	10p13	Hs.332706	65	protein targeting to Golgi cytoplasm Golgi apparatus Golgi organization signal transduction protein C-terminus binding cell death cellular protein localization Golgi to plasma membrane protein transport perinuclear region of cytoplasm
220478_at	0.215	5.601	2.541	2.241e-02	0.454	-3.346	APOL5	apolipoprotein L, 5	22	34443864	NM_030642	80831	22q12.3	Hs.326561	3	protein binding extracellular region cytoplasm lipid metabolic process lipid transport high-density lipoprotein binding lipid binding lipoprotein metabolic process
212310_at	0.332	5.350	2.541	2.243e-02	0.454	-3.347	MIA3	melanoma inhibitory activity family, member 3	1	220858066	D87742	375056	1q41	Hs.118474	13	positive regulation of leukocyte migration protein binding endoplasmic reticulum endoplasmic reticulum membrane exocytosis negative regulation of cell adhesion protein transport membrane integral to membrane negative regulation of cell migration wound healing
34471_at	1.727	6.034	2.541	2.244e-02	0.454	-3.348	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	17	-10234366	M36769	4626	17p13.1	Hs.700484	10	nucleotide binding motor activity actin binding calmodulin binding ATP binding cytoplasm striated muscle thick filament striated muscle contraction structural constituent of muscle myosin complex myofibril	Tight junction
207864_at	-0.228	2.775	-2.540	2.245e-02	0.454	-3.348	SCN7A	sodium channel, voltage-gated, type VII, alpha	2	-166969784	NM_002976	6332	2q21-q23	Hs.695947	11	voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport muscle contraction membrane integral to membrane sodium ion binding
207511_s_at	-0.294	5.553	-2.540	2.245e-02	0.454	-3.348	C2orf24	chromosome 2 open reading frame 24	2	-219744862	NM_015680	27013	2q35	Hs.4973	5	membrane integral to membrane
222083_at	0.282	5.101	2.540	2.246e-02	0.454	-3.349	GLYAT	glycine-N-acyltransferase	11	-58234136, -58232805	AW024233	10249	11q12.1	Hs.145384	12	mitochondrion acyl-CoA metabolic process acyltransferase activity response to toxin transferase activity glycine N-acyltransferase activity
229241_at	0.263	6.996	2.540	2.247e-02	0.454	-3.349	LDHD	lactate dehydrogenase D	16	-73703258	AI623801	197257	16q23.1	Hs.380929	5	D-lactate dehydrogenase (cytochrome) activity protein binding protein binding mitochondrion oxidoreductase activity FAD binding oxidation reduction	Pyruvate metabolism
218906_x_at	0.289	7.234	2.540	2.247e-02	0.454	-3.349	KLC2	kinesin light chain 2	11	65781340, 65781666, 65781749, 65781749	NM_022822	64837	11q13.2	Hs.280792	22	microtubule motor activity protein binding cytosol kinesin complex microtubule protein complex
221104_s_at	-0.473	8.611	-2.539	2.249e-02	0.454	-3.350	NIPSNAP3B	nipsnap homolog 3B (C. elegans)	9	106566271	NM_018376	55335	9q31.1	Hs.429294	5
236381_s_at	-0.435	5.023	-2.539	2.249e-02	0.454	-3.350	WDR8	WD repeat domain 8	1	-3537191	AW572779	49856	1p36.3	Hs.31714	8	protein binding cytoplasm
213864_s_at	-0.360	9.661	-2.538	2.254e-02	0.454	-3.352	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AI985751	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
236418_at	0.292	3.931	2.537	2.258e-02	0.455	-3.353	TTLL10	tubulin tyrosine ligase-like family, member 10	1	1099148, 1104939	AW772075	254173	1p36.33	Hs.454835	4	tubulin-tyrosine ligase activity cytoplasm cytoskeleton microtubule protein modification process ligase activity protein polyglycylation protein-glycine ligase activity
1562211_a_at	0.273	5.601	2.537	2.260e-02	0.455	-3.354	ZNF491	zinc finger protein 491	19	11770390	AK096593	126069	19p13.2	Hs.631634	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
205068_s_at	-0.292	5.604	-2.537	2.261e-02	0.455	-3.354	ARHGAP26	Rho GTPase activating protein 26	5	142130475	BE671084	23092	5q31	Hs.654668	13	GTPase activator activity Rho GTPase activator activity protein binding cellular_component intracellular cytoplasm cytoskeleton focal adhesion signal transduction nervous system development actin cytoskeleton organization cell junction
61297_at	-0.217	5.433	-2.537	2.261e-02	0.455	-3.354	CASKIN2	CASK interacting protein 2	17	-71007937, -71007937	AL037338	57513	17q25.1	Hs.274408	8	molecular_function cytoplasm biological_process
242002_at	0.346	4.931	2.537	2.261e-02	0.455	-3.354	NKAIN2	Na+/K+ transporting ATPase interacting 2	6	124166767	N62814	154215	6q21	Hs.656604	6	plasma membrane integral to membrane
215067_x_at	0.245	6.772	2.536	2.262e-02	0.455	-3.355	PRDX2	peroxiredoxin 2	19	-12772426, -12768633	AU147942	7001	19p13.2	Hs.432121	52	cytoplasm anti-apoptosis response to oxidative stress response to oxidative stress thioredoxin peroxidase activity oxidoreductase activity regulation of apoptosis cell redox homeostasis oxidation reduction
227442_at	0.237	6.930	2.536	2.263e-02	0.455	-3.355	COX18	COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)	4	-74139279	BG283902	285521	4q13.3	Hs.356697	5	mitochondrion mitochondrial inner membrane respiratory chain complex IV assembly protein transporter activity membrane integral to membrane integral to mitochondrial inner membrane protein insertion into mitochondrial membrane
221569_at	0.306	6.273	2.536	2.264e-02	0.455	-3.356	AHI1	Abelson helper integration site 1	6	-135750615, -135646804	AL136797	54806	6q23.3	Hs.386684	30
226143_at	0.346	7.538	2.536	2.266e-02	0.455	-3.356	RAI1	retinoic acid induced 1	17	17525511	BF984830	10743	17p11.2	Hs.655395	16	protein binding nucleus cytoplasm zinc ion binding metal ion binding
225612_s_at	-0.550	6.270	-2.535	2.267e-02	0.455	-3.357	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	3	184453725	BE672260	84002	3q28	Hs.718506	7	intracellular Golgi apparatus protein amino acid glycosylation multicellular organismal development central nervous system development galactosyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity lipopolysaccharide N-acetylglucosaminyltransferase activity glycolipid biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
200710_at	0.365	11.429	2.535	2.268e-02	0.455	-3.357	ACADVL	acyl-Coenzyme A dehydrogenase, very long chain	17	7063876	NM_000018	37	17p13-p11	Hs.437178 Hs.463928	30	long-chain-acyl-CoA dehydrogenase activity mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation electron carrier activity energy derivation by oxidation of organic compounds membrane mitochondrial nucleoid FAD binding oxidation reduction	Fatty acid metabolism Metabolic pathways
214663_at	-0.230	6.017	-2.535	2.269e-02	0.455	-3.358	DSTYK	dual serine/threonine and tyrosine protein kinase	1	-203378254	AB007941	25778	1q32.1	Hs.6874	9	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
202384_s_at	-0.222	5.895	-2.534	2.271e-02	0.455	-3.358	TCOF1	Treacher Collins-Franceschetti syndrome 1	5	149717394, 149717394	AW167713	6949	5q32-q33.1	Hs.519672 Hs.605019	39	skeletal system development transporter activity protein binding nucleus nucleolus transport
206393_at	-1.003	12.029	-2.534	2.271e-02	0.455	-3.358	TNNI2	troponin I type 2 (skeletal, fast)	11	1816808, 1817294, 1818007	NM_003282	7136	11p15.5	Hs.523403	29	skeletal muscle contraction actin binding protein binding nucleus troponin complex troponin T binding positive regulation of transcription
217367_s_at	-0.239	5.554	-2.533	2.276e-02	0.455	-3.360	ZHX3	zinc fingers and homeoboxes 3	20	-39240502	AB007855	23051	20q12	Hs.380133	13	transcription factor activity protein binding intracellular nucleus cytoplasm zinc ion binding sequence-specific DNA binding negative regulation of transcription, DNA-dependent metal ion binding
212571_at	0.219	5.988	2.533	2.277e-02	0.455	-3.361	CHD8	chromodomain helicase DNA binding protein 8	14	-20923197	U00955	57680	14q11.2	Hs.530698	17	nucleotide binding chromatin p53 binding DNA binding DNA helicase activity chromatin binding ATP binding nucleus chromatin assembly or disassembly beta-catenin binding DNA-dependent ATPase activity transcription activator activity transcription repressor activity chromatin modification hydrolase activity negative regulation of Wnt receptor signaling pathway methylated histone residue binding ATP-dependent chromatin remodeling protein complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase III promoter Wnt receptor signaling pathway through beta-catenin	Wnt signaling pathway
241866_at	0.555	4.232	2.533	2.277e-02	0.455	-3.361	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	AW975728	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
1553947_at	-0.205	5.024	-2.532	2.281e-02	0.455	-3.362	EXOSC6	exosome component 6	16	-68841634	NM_058219	118460	16q22.1	Hs.660633 Hs.719211	9	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
38703_at	-0.282	8.876	-2.532	2.281e-02	0.455	-3.362	DNPEP	aspartyl aminopeptidase	2	-219946423	AF005050	23549	2q35	Hs.258551	8	aminopeptidase activity protein binding cytoplasm vacuole proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding metal ion binding
230090_at	-1.116	5.755	-2.532	2.282e-02	0.455	-3.363	GDNF	glial cell derived neurotrophic factor	5	-37851509, -37851509, -37851509	AW296078	2668	5p13.1-p12	Hs.248114	86	neural crest cell migration extracellular region anti-apoptosis signal transduction nervous system development growth factor activity adult locomotory behavior positive regulation of specific transcription from RNA polymerase II promoter neuron projection development positive regulation of monooxygenase activity positive regulation of dopamine secretion protein homodimerization activity negative regulation of neuron apoptosis mRNA stabilization regulation of dopamine uptake
207564_x_at	-0.461	6.670	-2.532	2.283e-02	0.455	-3.363	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	70669657	NM_003605	8473	Xq13	Hs.405410	47	protein binding nucleus cytoplasm cytosol protein amino acid O-linked glycosylation signal transduction response to nutrient acetylglucosaminyltransferase activity transferase activity, transferring glycosyl groups MLL5-L complex	O-Glycan biosynthesis Metabolic pathways
213283_s_at	0.198	5.772	2.532	2.284e-02	0.455	-3.363	SALL2	sal-like 2 (Drosophila)	14	-21059071	BG285616	6297	14q11.1-q12	Hs.416358 Hs.719293	14	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
239288_at	-0.851	6.386	-2.532	2.284e-02	0.455	-3.363	TNIK	TRAF2 and NCK interacting kinase	3	-172547417, -172262985	BF431017	23043	3q26.2-q26.31	Hs.34024	14	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade transferase activity
214357_at	0.736	5.129	2.531	2.287e-02	0.456	-3.364	C1orf105	chromosome 1 open reading frame 105	1	170656452	AL035295	92346	1q24.3	Hs.517991	4
209242_at	0.528	4.967	2.530	2.289e-02	0.456	-3.365	PEG3	paternally expressed 3	19	-62013256, -62013256	AL042588	5178	19q13.4	Hs.719209	18	nucleic acid binding transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent apoptosis zinc ion binding metal ion binding
1560018_at	0.483	5.859	2.530	2.290e-02	0.456	-3.365	ARPP-21	cyclic AMP-regulated phosphoprotein, 21 kD	3	35658852, 35696119, 35697432	H44077	10777	3p22.3	Hs.475902 Hs.713605	7	molecular_function nucleic acid binding cellular_component cytoplasm biological_process
218977_s_at	0.320	5.319	2.530	2.291e-02	0.456	-3.366	TRNAU1AP	tRNA selenocysteine 1 associated protein 1	1	28752115	NM_017846	54952	1p35.3	Hs.533626	5	nucleotide binding selenocysteine incorporation RNA binding nucleus cytoplasm translation
211984_at	-0.342	10.402	-2.530	2.291e-02	0.456	-3.366	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	AI653730	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
213427_at	0.383	6.362	2.530	2.291e-02	0.456	-3.366	RPP40	ribonuclease P/MRP 40kDa subunit	6	-4940278	NM_006638	10799	6p25.1	Hs.511756	4	ribonuclease P activity protein binding nucleus nucleolar ribonuclease P complex nucleolus tRNA processing hydrolase activity
235128_at	-0.446	10.270	-2.529	2.294e-02	0.456	-3.367	SYNPO	synaptopodin	5	150000412, 150000412	AI569782	11346	5q33.1	Hs.435228 Hs.591256 Hs.714870	20	actin binding cytoplasm plasma membrane tight junction postsynaptic density actin cytoskeleton cell junction cell projection dendritic spine perikaryon synapse postsynaptic membrane
212539_at	-0.305	7.260	-2.529	2.296e-02	0.456	-3.368	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	AI422099	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
201910_at	-0.501	7.009	-2.528	2.300e-02	0.456	-3.369	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	13	97593434, 97593434	BF213279	10160	13q32.2	Hs.403917	9	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity binding intracellular cytoplasm cytoskeleton cytoskeletal protein binding extrinsic to membrane regulation of Rho protein signal transduction
227334_at	0.618	9.327	2.527	2.303e-02	0.456	-3.370	USP54	ubiquitin specific peptidase 54	10	-74927301	AW242125	159195	10q22.2	Hs.657355	6	ubiquitin thiolesterase activity protein binding ubiquitin-dependent protein catabolic process
219655_at	-0.351	6.289	-2.527	2.303e-02	0.456	-3.370	C7orf10	chromosome 7 open reading frame 10	7	40141099	NM_024728	79783	7p14.1	Hs.586313	9	metabolic process transferase activity
211961_s_at	-0.377	9.232	-2.527	2.303e-02	0.456	-3.371	RAB7A	RAB7A, member RAS oncogene family	3	129927668	AK000826	7879	3q21.3	Hs.15738 Hs.716392	64	nucleotide binding GTPase activity protein binding GTP binding cytoplasm lysosome late endosome Golgi apparatus endocytosis small GTPase mediated signal transduction protein transport cytoplasmic vesicle melanosome phagocytic vesicle
240770_at	0.546	2.734	2.527	2.304e-02	0.456	-3.371	TMEM171	transmembrane protein 171	5	72452143	AW058459	134285	5q13.2	Hs.162246	5	membrane integral to membrane
208897_s_at	-0.339	7.006	-2.527	2.304e-02	0.456	-3.371	DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	2	118288724	BC003360	8886	2q14.1	Hs.363492	6	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding hydrolase activity
212272_at	-0.813	4.671	-2.527	2.305e-02	0.456	-3.371	LPIN1	lipin 1	2	11804190	AA813260	23175	2p25.1	Hs.467740	28	molecular_function nucleus lipid metabolic process phosphatidate phosphatase activity ruffle organization actin cytoskeleton reorganization cellular response to insulin stimulus regulation of fat cell differentiation
242851_at	0.295	5.626	2.527	2.306e-02	0.456	-3.371	KIAA1919	KIAA1919	6	111687174	BE964989	91749	6q22	Hs.400572	5	plasma membrane ion transport sodium ion transport carbohydrate transport symporter activity integral to membrane sodium ion binding
236217_at	0.232	2.847	2.527	2.306e-02	0.456	-3.372	SLC31A1	solute carrier family 31 (copper transporters), member 1	9	115023628	AI885320	1317	9q31-q32	Hs.532315	24	copper ion transmembrane transporter activity copper ion binding integral to plasma membrane ion transport copper ion transport membrane
226878_at	0.270	5.212	2.527	2.307e-02	0.456	-3.372	HLA-DOA	major histocompatibility complex, class II, DO alpha	6	-33079937, -4352783, -4157999	AL581873	3111	6p21.3	Hs.631991	40	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane plasma membrane immune response integral to membrane antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II receptor activity MHC class II protein complex regulation of T cell differentiation	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
201428_at	-0.206	4.092	-2.526	2.310e-02	0.457	-3.373	CLDN4	claudin 4	7	72883128	NM_001305	1364	7q11.23	Hs.647036 Hs.699253 Hs.718794	55	transmembrane receptor activity structural molecule activity plasma membrane integral to plasma membrane tight junction pathogenesis calcium-independent cell-cell adhesion cell junction identical protein binding	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration
222134_at	-0.377	4.988	-2.526	2.311e-02	0.457	-3.374	DDO	D-aspartate oxidase	6	-110820075	AL050350	8528	6q21	Hs.591348	11	D-amino-acid oxidase activity binding peroxisome aspartate catabolic process D-aspartate oxidase activity oxidoreductase activity oxidation reduction	Alanine, aspartate and glutamate metabolism
213998_s_at	0.636	6.171	2.525	2.314e-02	0.457	-3.374	DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	22	-37209388, -37209388	AW188131	10521	22q13.1	Hs.528305 Hs.665429 Hs.719084	28	nucleotide binding RNA binding RNA helicase activity ATP binding nucleus RNA processing ATP-dependent helicase activity RNA-dependent ATPase activity hydrolase activity
209448_at	-0.428	6.969	-2.525	2.315e-02	0.457	-3.375	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	BC002439	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
216909_at	0.278	5.520	2.524	2.317e-02	0.457	-3.376	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	10	-99106448	AK021460	23223	10q24.1	Hs.434251	15	protein binding nucleus nucleolus membrane integral to membrane
224501_at	-0.378	7.785	-2.524	2.318e-02	0.457	-3.376	C1orf170	chromosome 1 open reading frame 170	1	-900441	BC006300	84808	1p36.33	Hs.271462	2
208869_s_at	-0.479	6.940	-2.523	2.321e-02	0.457	-3.377	GABARAPL1	GABA(A) receptor-associated protein like 1	12	10256755	AF087847	23710	12p13.2	Hs.524250	18	protein binding intracellular cytoplasm autophagic vacuole endoplasmic reticulum Golgi apparatus microtubule membrane beta-tubulin binding GABA receptor binding	Regulation of autophagy
209936_at	0.247	5.370	2.523	2.323e-02	0.457	-3.378	RBM5	RNA binding motif protein 5	3	50101371	AF107493	10181	3p21.3	Hs.439480	27	nucleotide binding spliceosome assembly regulation of alternative nuclear mRNA splicing, via spliceosome DNA binding mRNA binding protein binding intracellular nucleus spliceosomal complex nucleolus zinc ion binding negative regulation of cell proliferation RNA splicing positive regulation of apoptosis positive regulation of apoptosis metal ion binding
1554892_a_at	0.229	3.218	2.523	2.324e-02	0.457	-3.378	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	11	59580676	AY095480	932	11q12.1	Hs.99960	7	receptor activity protein binding cytoplasm signal transduction membrane integral to membrane perinuclear region of cytoplasm
217983_s_at	0.321	6.444	2.523	2.324e-02	0.457	-3.379	RNASET2	ribonuclease T2	6	-167262993	NM_003730	8635	6q27	Hs.529989	11	RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity
217489_s_at	0.170	2.368	2.523	2.326e-02	0.457	-3.379	IL6R	interleukin 6 receptor	1	152644292	S72848	3570	1q21	Hs.709210	132	hepatic immune response monocyte chemotaxis positive regulation of leukocyte chemotaxis receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity receptor binding extracellular region plasma membrane interleukin-6 receptor complex acute-phase response integral to membrane apical plasma membrane enzyme binding endocrine pancreas development endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production response to cytokine stimulus positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity regulation of apoptosis positive regulation of osteoblast differentiation positive regulation of anti-apoptosis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium interleukin-6-mediated signaling pathway ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
229982_at	0.293	5.378	2.522	2.326e-02	0.457	-3.379	QSER1	glutamine and serine rich 1	11	32871367	AW195525	79832	11p13	Hs.369368	2
215101_s_at	0.226	3.350	2.522	2.327e-02	0.457	-3.380	CXCL5	chemokine (C-X-C motif) ligand 5	4	-75080222	BG166705	6374	4q12-q13	Hs.89714	49	extracellular region extracellular space chemotaxis immune response signal transduction cell-cell signaling chemokine activity positive regulation of cell proliferation	Cytokine-cytokine receptor interaction Chemokine signaling pathway
204524_at	-0.202	7.350	-2.522	2.329e-02	0.457	-3.380	PDPK1	3-phosphoinositide dependent protein kinase-1	16	2527970	NM_002613	5170	16p13.3	Hs.459691	103	nucleotide binding 3-phosphoinositide-dependent protein kinase activity protein binding ATP binding cytoplasm cytosol plasma membrane plasma membrane negative regulation of protein kinase activity intracellular signaling cascade transferase activity peptidyl-threonine phosphorylation actin cytoskeleton organization activation of protein kinase B activity cellular response to insulin stimulus regulation of establishment of protein localization	PPAR signaling pathway mTOR signaling pathway Focal adhesion Insulin signaling pathway Endometrial cancer Prostate cancer Non-small cell lung cancer
219957_at	0.369	6.834	2.522	2.329e-02	0.457	-3.380	RUFY2	RUN and FYVE domain containing 2	10	-69806955, -69773280	NM_017987	55680	10q21.3	Hs.653144	5	nucleus zinc ion binding metal ion binding
213463_s_at	-0.278	6.371	-2.522	2.329e-02	0.457	-3.380	FAM149B1	family with sequence similarity 149, member B1	10	74597882	AW300504	317662	10q22.2	Hs.408577	4
203605_at	-0.314	7.496	-2.522	2.329e-02	0.457	-3.380	SRP54	signal recognition particle 54kDa	14	34521854	NM_003136	6729	14q13.2	Hs.167535	15	nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane, translocation SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition drug binding 7S RNA binding nuclear speck GDP binding endoplasmic reticulum signal peptide binding response to drug ribonucleoprotein binding	Protein export
223617_x_at	-0.186	7.718	-2.521	2.330e-02	0.457	-3.381	ATAD3B	ATPase family, AAA domain containing 3B	1	1397026	BC002542	83858	1p36.33	Hs.23413	9	nucleotide binding ATP binding nucleoside-triphosphatase activity
220929_at	0.212	5.086	2.521	2.331e-02	0.457	-3.381	GALNT8	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)	12	4700012	NM_017417	26290	12p13.3	Hs.511985	2	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding	O-Glycan biosynthesis Metabolic pathways
231382_at	0.355	4.546	2.521	2.332e-02	0.457	-3.381	FGF18	fibroblast growth factor 18	5	170779271	AI798863	8817	5q34	Hs.87191	25	angiogenesis intramembranous ossification endochondral ossification chondrocyte development extracellular region extracellular region extracellular space nucleolus signal transduction cell-cell signaling growth factor activity positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis lung development positive regulation of vascular endothelial growth factor receptor signaling pathway	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
227681_at	-0.201	6.124	-2.521	2.332e-02	0.457	-3.382	ZFP36L2	zinc finger protein 36, C3H type-like 2	2	-43303044	BF589368	678	2p22.3-p21	Hs.503093	8	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay transcription factor activity RNA binding nucleus cytoplasm zinc ion binding cell proliferation regulation of mRNA stability metal ion binding
1564075_a_at	0.253	2.858	2.521	2.334e-02	0.457	-3.382	FLJ35848	hypothetical protein FLJ35848	17	40089507	AK097747	284071	17q21.31	Hs.349758	2
202147_s_at	-0.642	7.163	-2.521	2.334e-02	0.457	-3.382	IFRD1	interferon-related developmental regulator 1	7	111850461, 111877750	NM_001550	3475	7q22-q31	Hs.7879	23	binding nucleus multicellular organismal development myoblast cell fate determination adult somatic muscle development muscle cell differentiation
201526_at	0.303	8.215	2.519	2.340e-02	0.458	-3.384	ARF5	ADP-ribosylation factor 5	7	127015752	NM_001662	381	7q31.3	Hs.653202	18	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
200828_s_at	-0.456	8.457	-2.519	2.341e-02	0.458	-3.385	ZNF207	zinc finger protein 207	17	27701269	BE871379	7756	17q11.2	Hs.500775	7	transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201408_at	-0.478	9.614	-2.519	2.341e-02	0.458	-3.385	PPP1CB	protein phosphatase 1, catalytic subunit, beta isoform	2	28828117, 28828129	W67887	5500	2p23	Hs.591571 Hs.702907	42	protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding cell division MLL5-L complex	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton Insulin signaling pathway
1569206_at	0.303	6.172	2.519	2.343e-02	0.458	-3.386	TCP11L2	t-complex 11 (mouse)-like 2	12	105220710	BC017872	255394	12q23.3	Hs.696047	1
214372_x_at	0.219	7.265	2.519	2.343e-02	0.458	-3.386	ERN2	endoplasmic reticulum to nucleus signaling 2	16	-23609126	AI732416	10595	16p12.2	Hs.592041	7	nucleotide binding magnesium ion binding endonuclease activity protein serine/threonine kinase activity ATP binding endoplasmic reticulum mRNA processing protein amino acid phosphorylation apoptosis induction of apoptosis response to stress cell cycle arrest membrane integral to membrane rRNA catabolic process negative regulation of transcription transferase activity hydrolase activity endoribonuclease activity, producing 5'-phosphomonoesters
201091_s_at	-0.380	7.916	-2.519	2.343e-02	0.458	-3.386	CBX3	chromobox homolog 3 (HP1 gamma homolog, Drosophila)	7	26207623, 26207848	BE748755	11335	7p15.2	Hs.381189 Hs.706294	45	condensed chromosome, centromeric region chromatin chromatin binding nucleus nuclear inner membrane polytene chromosome chromocenter nuclear euchromatin spindle chromatin assembly or disassembly chromatin remodeling negative regulation of transcription general transcriptional repressor activity enzyme binding protein domain specific binding nuclear centromeric heterochromatin
1554462_a_at	-0.591	7.075	-2.519	2.344e-02	0.458	-3.386	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	AF115512	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
242442_x_at	0.317	3.570	2.518	2.345e-02	0.458	-3.386	RG9MTD2	RNA (guanine-9-) methyltransferase domain containing 2	4	-100686894, -100686894	AL515269	93587	4q23	Hs.380412	1	methyltransferase activity transferase activity
204125_at	-0.466	9.234	-2.518	2.345e-02	0.458	-3.386	NDUFAF1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1	15	-39466842	NM_016013	51103	15q11.2-q21.3	Hs.106529	11	mitochondrion mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone protein complex assembly unfolded protein binding
234130_at	-0.324	7.801	-2.518	2.348e-02	0.458	-3.387	LDB3	LIM domain binding 3	10	88418300, 88418405, 88418405	AL359621	11155	10q22.3-q23.2	Hs.657271	15	protein binding cytoplasm cytoskeleton zinc ion binding Z disc pseudopodium metal ion binding perinuclear region of cytoplasm
205549_at	-0.195	4.709	-2.518	2.349e-02	0.458	-3.388	PCP4	Purkinje cell protein 4	21	40161216	NM_006198	5121	21q22.2	Hs.80296	9	nucleus cytosol central nervous system development
241382_at	0.225	3.681	2.517	2.350e-02	0.458	-3.388	PCP4L1	Purkinje cell protein 4 like 1	1	159495140	W22165	654790	1q23.3	Hs.433150	6
231149_s_at	-0.220	3.262	-2.517	2.350e-02	0.458	-3.388	ULK4	unc-51-like kinase 4 (C. elegans)	3	-41263093	AI828638	54986	3p22.1	Hs.656192	7	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
219341_at	0.285	5.041	2.517	2.352e-02	0.458	-3.389	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	8	1699276	NM_018941	2055	8p23	Hs.127675	15	age-dependent response to oxidative stress endoplasmic reticulum ER-Golgi intermediate compartment phospholipid metabolic process lipid transport mitochondrial membrane organization lysosome organization nervous system development adult walking behavior cholesterol metabolic process associative learning regulation of cell size lipid biosynthetic process membrane integral to membrane spinal cord motor neuron differentiation social behavior negative regulation of apoptosis cellular protein catabolic process cellular macromolecule catabolic process photoreceptor cell maintenance negative regulation of proteolysis ceramide biosynthetic process musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate uptake during transmission of nerve impulse retina development in camera-type eye neurofilament cytoskeleton organization
223716_s_at	-0.251	9.448	-2.516	2.355e-02	0.458	-3.390	ZRANB2	zinc finger, RAN-binding domain containing 2	1	-71301561	AF065391	9406	1p31	Hs.194718	18	transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding
219959_at	0.808	5.116	2.516	2.358e-02	0.459	-3.391	MOCOS	molybdenum cofactor sulfurase	18	32021477	NM_017947	55034	18q12	Hs.405028	10	cellular_component Mo-molybdopterin cofactor biosynthetic process metabolic process Mo-molybdopterin cofactor sulfurase activity lyase activity molybdenum ion binding pyridoxal phosphate binding molybdopterin cofactor metabolic process
1553070_a_at	-0.448	7.099	-2.516	2.358e-02	0.459	-3.391	MYOZ3	myozenin 3	5	150020596	NM_133371	91977	5q33.1	Hs.91626	7	protein binding cytoplasm Z disc
204601_at	-0.351	5.473	-2.515	2.359e-02	0.459	-3.392	N4BP1	NEDD4 binding protein 1	16	-47130137	NM_014664	9683	16q12.1	Hs.511839	6	nucleus
228419_at	-0.228	5.995	-2.515	2.359e-02	0.459	-3.392	METRN	meteorin, glial cell differentiation regulator	16	705173	BF432260	79006	16p13.3	Hs.533772	6	extracellular region extracellular space multicellular organismal development nervous system development glial cell differentiation positive regulation of axonogenesis
238846_at	0.261	2.444	2.515	2.360e-02	0.459	-3.392	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	18	58143527	AW026379	8792	18q22.1	Hs.204044	79	receptor activity protein binding signal transduction cell-cell signaling positive regulation of cell proliferation membrane integral to membrane	Cytokine-cytokine receptor interaction
226967_at	0.259	6.463	2.514	2.365e-02	0.459	-3.394	FIZ1	FLT3-interacting zinc finger 1	19	-60794548	BG231981	84922	19q13.42	Hs.515617	5	nucleic acid binding receptor binding intracellular nucleus cytoplasm zinc ion binding protein kinase binding regulation of transcription metal ion binding
38340_at	0.263	6.264	2.513	2.368e-02	0.459	-3.395	HIP1R	huntingtin interacting protein 1 related	12	121885991	AB014555	9026	12q24	Hs.524815 Hs.714965	19	actin binding protein binding cytoplasm coated pit receptor-mediated endocytosis biological_process membrane clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding perinuclear region of cytoplasm
210719_s_at	-0.315	5.457	-2.513	2.368e-02	0.459	-3.395	HMG20B	high-mobility group 20B	19	3523942	BC002552	10362	19p13.3	Hs.406534	18	transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle chromatin modification
1552580_at	-0.174	4.358	-2.513	2.369e-02	0.459	-3.395	TRIML2	tripartite motif family-like 2	4	-189249420	NM_173553	205860	4q35.2	Hs.276429	1
201668_x_at	0.236	4.665	2.513	2.372e-02	0.459	-3.396	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	AW163148	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
226618_at	-0.543	7.177	-2.513	2.372e-02	0.459	-3.396	FLJ25076	probable ubiquitin-conjugating enzyme E2 FLJ25076	5	6501735	AW572911	134111	5p15.31	Hs.126856	3	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
220589_s_at	-0.246	6.025	-2.513	2.372e-02	0.459	-3.396	ITFG2	integrin alpha FG-GAP repeat containing 2	12	2792123	NM_018463	55846	12p13.33	Hs.446098 Hs.448720	2
218853_s_at	-0.510	7.362	-2.512	2.373e-02	0.459	-3.397	MOSPD1	motile sperm domain containing 1	X	-133849327	NM_019556	56180	Xq26.3	Hs.590789	4	structural molecule activity membrane integral to membrane
1561130_at	-0.240	4.746	-2.512	2.373e-02	0.459	-3.397	C12orf51	chromosome 12 open reading frame 51	12	-111082493	AF086006	283450	12q24.13	Hs.695995	3	intracellular protein modification process membrane integral to membrane ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process
219916_s_at	0.249	5.127	2.512	2.373e-02	0.459	-3.397	RNF39	ring finger protein 39	6	-30146021, -1486649, -1284968	NM_025236	80352	6p21.3	Hs.121178	10	protein binding cellular_component cytoplasm biological_process zinc ion binding metal ion binding
210870_s_at	-0.494	7.276	-2.512	2.373e-02	0.459	-3.397	EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	6	-145988132	BC005286	7957	6q24	Hs.486696	37	protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm endoplasmic reticulum cytosol polysome plasma membrane carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity carbohydrate binding
202751_at	-0.323	3.722	-2.512	2.374e-02	0.459	-3.397	TFIP11	tuftelin interacting protein 11	22	-25217894	NM_012143	24144	22q12.1	Hs.20225	19	nucleic acid binding protein binding proteinaceous extracellular matrix intracellular nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing nuclear speck biomineral formation
211792_s_at	-0.295	6.716	-2.512	2.375e-02	0.459	-3.397	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	1	51206954, 51208229	U17074	1031	1p32	Hs.525324 Hs.716664	45	regulation of cyclin-dependent protein kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm induction of apoptosis cell cycle cell cycle arrest negative regulation of cell proliferation protein kinase binding negative regulation of cell growth negative regulation of phosphorylation oligodendrocyte differentiation	Cell cycle
225203_at	0.501	8.671	2.511	2.378e-02	0.459	-3.399	PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	8	145692916	AI742931	84988	8q24.3	Hs.521937	9	protein binding plasma membrane
204622_x_at	-0.776	4.719	-2.511	2.380e-02	0.459	-3.399	NR4A2	nuclear receptor subfamily 4, group A, member 2	2	-156889189	NM_006186	4929	2q22-q23	Hs.563344	76	transcription factor activity steroid hormone receptor activity nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding cellular response to extracellular stimulus sequence-specific DNA binding metal ion binding response to protein stimulus
211715_s_at	0.529	7.004	2.511	2.380e-02	0.459	-3.399	BDH1	3-hydroxybutyrate dehydrogenase, type 1	3	-198721050, -198721050	BC005844	622	3q29	Hs.274539	11	3-hydroxybutyrate dehydrogenase activity 3-hydroxybutyrate dehydrogenase activity binding mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix oxidoreductase activity oxidation reduction	Synthesis and degradation of ketone bodies Butanoate metabolism Metabolic pathways
223804_s_at	0.339	7.609	2.510	2.383e-02	0.459	-3.400	THUMPD3	THUMP domain containing 3	3	9379716	BC001622	25917	3p25.3	Hs.443081	5	RNA binding protein binding methyltransferase activity transferase activity
202190_at	0.487	5.919	2.510	2.384e-02	0.459	-3.401	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	20	54400833, 54400980, 54401113	NM_001324	1477	20q13.2	Hs.172865	19	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA polyadenylation mRNA cleavage
203857_s_at	0.326	5.307	2.510	2.384e-02	0.459	-3.401	PDIA5	protein disulfide isomerase family A, member 5	3	124268654	NM_006810	10954	3q21.1	Hs.477352	9	protein disulfide isomerase activity endoplasmic reticulum endoplasmic reticulum lumen protein folding response to stress oxidoreductase activity isomerase activity cell redox homeostasis oxidation reduction
218847_at	-0.294	5.262	-2.510	2.384e-02	0.459	-3.401	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	3	-186844220	NM_006548	10644	3q27.2	Hs.35354	55	nucleotide binding RNA binding protein binding nucleus cytoplasm biological_process anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process cytoskeletal part translation regulator activity mRNA 5'-UTR binding
204171_at	-0.290	5.842	-2.510	2.386e-02	0.459	-3.401	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	NM_003161	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
202383_at	-0.179	6.424	-2.510	2.386e-02	0.459	-3.402	KDM5C	lysine (K)-specific demethylase 5C	X	-53237228	NM_004187	8242	Xp11.22-p11.21	Hs.631768	17	molecular_function DNA binding iron ion binding protein binding cellular_component intracellular nucleus biological_process zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
206060_s_at	-0.215	3.065	-2.509	2.388e-02	0.459	-3.402	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	1	-114177091, -114157962	NM_015967	26191	1p13.3-p13.1	Hs.535276 Hs.719840	213	protein tyrosine phosphatase activity protein binding cytoplasm protein amino acid dephosphorylation signal transduction hydrolase activity
1558041_a_at	0.261	5.030	2.509	2.388e-02	0.459	-3.402	KIAA0895L	KIAA0895-like	16	-65767005	AL834156	653319	16q22.1	Hs.651201	2
226214_at	-0.328	8.802	-2.509	2.388e-02	0.459	-3.402	GDE1	glycerophosphodiester phosphodiesterase 1	16	-19420515	BE677894	51573	16p12-p11.2	Hs.512607	8	magnesium ion binding cytoplasm glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity glycerophosphoinositol glycerophosphodiesterase activity	Glycerophospholipid metabolism
212226_s_at	0.300	8.307	2.509	2.389e-02	0.459	-3.403	PPAP2B	phosphatidic acid phosphatase type 2B	1	-56733020	AA628586	8613	1pter-p22.1	Hs.405156 Hs.715848	16	blood vessel development gastrulation with mouth forming second phosphoprotein phosphatase activity Golgi apparatus cytosol plasma membrane lipid metabolic process phospholipid metabolic process phosphatidate phosphatase activity phosphatidate phosphatase activity germ cell migration integral to membrane hydrolase activity regulation of Wnt receptor signaling pathway lipid phosphatase activity	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
203340_s_at	-0.489	9.488	-2.509	2.389e-02	0.459	-3.403	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	2	-172348160	NM_003705	8604	2q24	Hs.470608	27	transporter activity L-glutamate transmembrane transporter activity calcium ion binding protein binding mitochondrion mitochondrial inner membrane transport L-aspartate transmembrane transporter activity aspartate transport L-glutamate transport membrane integral to membrane malate-aspartate shuttle response to calcium ion
220349_s_at	0.316	7.377	2.509	2.390e-02	0.459	-3.403	ENGASE	endo-beta-N-acetylglucosaminidase	17	74582613	NM_022759	64772	17q25.3	Hs.29288	5	intracellular cytoplasm cytosol metabolic process hydrolase activity, acting on glycosyl bonds mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	Other glycan degradation
223538_at	0.428	7.560	2.509	2.391e-02	0.459	-3.403	SERF1A	small EDRK-rich factor 1A (telomeric)	5	69356827, 69356827, 70232245, 70232245, -510079, -499652	AF073518	8293	5q12.2-q13.3	Hs.559428	7
233197_at	0.343	4.984	2.509	2.391e-02	0.459	-3.403	KLHL9	kelch-like 9 (Drosophila)	9	-21321017	AK022805	55958	9p22	Hs.522029 Hs.701778 Hs.710126	4	protein binding modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
212631_at	-0.307	6.848	-2.507	2.397e-02	0.459	-3.405	STX7	syntaxin 7	6	-132820355	AI566082	8417	6q23.1	Hs.593148 Hs.605992	31	SNAP receptor activity endosome Golgi apparatus intracellular protein transport post-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
240172_at	-0.510	5.537	-2.507	2.397e-02	0.459	-3.406	ERGIC2	ERGIC and golgi 2	12	-29384845	AA102332	51290	12p11.22	Hs.339453	11	nucleus cytoplasm endoplasmic reticulum Golgi apparatus membrane integral to membrane vesicle-mediated transport
207253_s_at	-0.240	7.180	-2.507	2.399e-02	0.459	-3.406	UBN1	ubinuclein 1	16	4837912, 4842077	NM_016936	29855	16p13.3	Hs.440219	9	transcription factor activity nucleus nucleoplasm tight junction regulation of transcription from RNA polymerase II promoter chromatin modification cell junction interspecies interaction between organisms
202799_at	0.266	8.734	2.506	2.401e-02	0.459	-3.407	CLPP	ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)	19	6312462	NM_006012	8192	19p13.3	Hs.515092	9	nucleotide binding serine-type endopeptidase activity protein binding ATP binding mitochondrion proteolysis peptidase activity
204223_at	0.388	5.014	2.506	2.403e-02	0.460	-3.408	PRELP	proline/arginine-rich end leucine-rich repeat protein	1	201711505	NM_002725	5549	1q32	Hs.632481	13	skeletal system development extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix cell aging
1558738_at	-0.415	6.280	-2.506	2.405e-02	0.460	-3.409	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	16	65765370	BU785956	8996	16q21-q23	Hs.513667	22	RNA binding intracellular nucleus nucleolus cytoplasm cytosol mRNA processing anti-apoptosis RNA splicing identical protein binding regulation of apoptosis
224931_at	-0.265	7.334	-2.505	2.406e-02	0.460	-3.409	SLC41A3	solute carrier family 41, member 3	3	-127207889, -127207889	AK021925	54946	3q21.2-q21.3	Hs.573007	5	plasma membrane cation transport cation transmembrane transporter activity integral to membrane
209405_s_at	-0.195	6.076	-2.505	2.407e-02	0.460	-3.409	FAM3A	family with sequence similarity 3, member A	X	-153387699	BC002934	60343	Xq28	Hs.289108	7	molecular_function extracellular region biological_process
208823_s_at	-0.278	6.695	-2.505	2.408e-02	0.460	-3.410	PCTK1	PCTAIRE protein kinase 1	X	46962471, 46963058	BE787860	5127	Xp11.3-p11.23	Hs.496068	24	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
224874_at	-0.384	7.384	-2.505	2.408e-02	0.460	-3.410	POLR1D	polymerase (RNA) I polypeptide D, 16kDa	13	27094002, 27094028	N32181	51082	13q12.2	Hs.507584	15	DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm transcription protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
241779_at	0.254	5.699	2.505	2.410e-02	0.460	-3.410	MTX3	metaxin 3	5	-79308294	BE898126	345778	5q14.1	Hs.531418	3	mitochondrion mitochondrial outer membrane protein targeting to mitochondrion protein transport membrane
202006_at	-0.298	7.549	-2.504	2.411e-02	0.460	-3.411	PTPN12	protein tyrosine phosphatase, non-receptor type 12	7	77004708, 77005287	NM_002835	5782	7q11.23	Hs.61812	53	non-membrane spanning protein tyrosine phosphatase activity protein binding soluble fraction cytoplasm cytosol protein amino acid dephosphorylation hydrolase activity SH3 domain binding
208946_s_at	-0.372	8.279	-2.504	2.412e-02	0.460	-3.411	BECN1	beclin 1, autophagy related	17	-38215675	AF139131	8678	17q21	Hs.716464	56	protein binding cytoplasm Golgi apparatus trans-Golgi network autophagy anti-apoptosis cellular defense response negative regulation of cell proliferation response to virus membrane cytoplasmic membrane-bounded vesicle positive regulation of macroautophagy protein complex	Regulation of autophagy
230563_at	0.516	4.497	2.504	2.412e-02	0.460	-3.411	RASGEF1A	RasGEF domain family, member 1A	10	-43009989	BF446578	221002	10q11.21	Hs.125293	4	guanyl-nucleotide exchange factor activity intracellular regulation of small GTPase mediated signal transduction
228950_s_at	-0.444	4.267	-2.504	2.412e-02	0.460	-3.411	GPR177	G protein-coupled receptor 177	1	-68363628, -68336738	AL534095	79971	1p31.3	Hs.647659	8	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
202696_at	-0.271	8.252	-2.504	2.415e-02	0.460	-3.412	OXSR1	oxidative-stress responsive 1	3	38182029	NM_005109	9943	3p22-p21.3	Hs.475970	21	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation response to oxidative stress protein kinase cascade transferase activity identical protein binding
206601_s_at	0.251	3.310	2.503	2.416e-02	0.460	-3.412	HOXD3	homeobox D3	2	176737050	BC005124	3232	2q31.1	Hs.93574	25	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding positive regulation of neuron differentiation embryonic skeletal system morphogenesis cartilage development
34210_at	0.366	3.347	2.503	2.417e-02	0.460	-3.413	CD52	CD52 molecule	1	26516997	N90866	1043	1p36	Hs.276770	27	membrane fraction plasma membrane integral to plasma membrane elevation of cytosolic calcium ion concentration anchored to membrane respiratory burst
210942_s_at	-1.203	4.696	-2.503	2.418e-02	0.460	-3.413	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	3	99934261	AB022918	10402	3q12.1	Hs.148716	5	Golgi apparatus amino sugar metabolic process protein amino acid glycosylation glycolipid metabolic process sialyltransferase activity protein lipoylation membrane integral to membrane integral to Golgi membrane	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
218630_at	0.176	5.884	2.503	2.418e-02	0.460	-3.413	MKS1	Meckel syndrome, type 1	17	-53637796	NM_017777	54903	17q22	Hs.408843	13
206366_x_at	0.217	4.333	2.503	2.419e-02	0.460	-3.414	XCL1	chemokine (C motif) ligand 1	1	166812479	U23772	6375	1q23	Hs.546295	39	extracellular region extracellular space cellular calcium ion homeostasis chemotaxis immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
238902_at	0.375	6.656	2.503	2.420e-02	0.460	-3.414	PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	8	-52892692	T85248	115294	8q11.23	Hs.308480	3	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cytoplasm protein modification process
214669_x_at	0.354	5.412	2.502	2.422e-02	0.460	-3.415	IGKC	immunoglobulin kappa constant	2		BG485135	3514	2p12	Hs.449621 Hs.703932	31	antigen binding protein binding extracellular region extracellular region immune response
218358_at	0.311	7.095	2.502	2.422e-02	0.460	-3.415	CRELD2	cysteine-rich with EGF-like domains 2	22	48698286	NM_024324	79174	22q13.33	Hs.211282	9	calcium ion binding extracellular region endoplasmic reticulum
208093_s_at	-0.272	7.737	-2.502	2.423e-02	0.460	-3.415	NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	17	8279903	NM_030808	81565	17p13.1	Hs.372123	38	condensed chromosome kinetochore protein binding cytoplasm centrosome spindle cytoskeleton microtubule transport chromosome segregation multicellular organismal development nervous system development cell differentiation
213935_at	0.251	6.708	2.502	2.423e-02	0.460	-3.415	ABHD5	abhydrolase domain containing 5	3	43707378	AF007132	51099	3p21	Hs.19385	14	1-acylglycerol-3-phosphate O-acyltransferase activity triacylglycerol lipase activity protein binding cytoplasm cytosol lipid metabolic process fatty acid metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process negative regulation of sequestering of triglyceride positive regulation of triglyceride catabolic process monolayer-surrounded lipid storage body transferase activity hydrolase activity cell differentiation lysophosphatidic acid acyltransferase activity
1552482_at	0.195	2.332	2.502	2.424e-02	0.460	-3.415	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	2	-204014436, -204006783	NM_025252	65059	2q33	Hs.471162	13	nucleus cytoplasm cytoskeleton plasma membrane cell-matrix adhesion signal transduction lamellipodium filopodium
244504_x_at	-0.192	5.604	-2.500	2.430e-02	0.461	-3.418	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AW139048	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
225545_at	-0.726	9.032	-2.500	2.431e-02	0.461	-3.418	EEF2K	eukaryotic elongation factor-2 kinase	16	22125092	BF001312	29904	16p12.2	Hs.498892	22	nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP binding cytoplasm cytosol translational elongation protein amino acid phosphorylation translation factor activity, nucleic acid binding transferase activity
218129_s_at	-0.458	6.516	-2.500	2.432e-02	0.461	-3.418	NFYB	nuclear transcription factor Y, beta	12	-103034987	NM_006166	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
233589_x_at	-0.237	6.070	-2.499	2.436e-02	0.461	-3.420	C9orf167	chromosome 9 open reading frame 167	9	139292100	AK000392	54863	9q34.3	Hs.495541	1	nucleotide binding ATP binding endoplasmic reticulum membrane integral to membrane nucleoside-triphosphatase activity chaperone mediated protein folding requiring cofactor
224804_s_at	0.230	7.498	2.499	2.436e-02	0.461	-3.420	C15orf17	chromosome 15 open reading frame 17	15	-72979380	AU152410	57184	15q24.1	Hs.367690	4
205445_at	0.277	4.081	2.499	2.437e-02	0.461	-3.420	PRL	prolactin	6	-22395457, -22395456	NM_000948	5617	6p22.2-p21.3	Hs.1905	118	prolactin receptor binding hormone activity extracellular region cell surface receptor linked signal transduction female pregnancy lactation cell proliferation regulation of multicellular organism growth positive regulation of JAK-STAT cascade	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Jak-STAT signaling pathway
216389_s_at	0.280	6.333	2.499	2.438e-02	0.461	-3.421	DCAF11	DDB1 and CUL4 associated factor 11	14	23653745, 23653825, 23654331, 23654333	AF283773	80344	14q11.2	Hs.525251	9	protein binding
210378_s_at	-0.186	7.301	-2.499	2.439e-02	0.461	-3.421	SSNA1	Sjogren syndrome nuclear autoantigen 1	9	139202874	BC004118	8636	9q34.3	Hs.530314	6	nucleus centrosome identical protein binding
210632_s_at	-0.395	9.118	-2.498	2.441e-02	0.461	-3.422	SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	17	45598364	L35853	6442	17q21	Hs.463412	23	calcium ion binding protein binding cytoplasm cytoskeleton muscle contraction muscle organ development dystrophin-associated glycoprotein complex sarcoglycan complex integral to membrane sarcolemma membrane raft	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
204440_at	0.260	5.614	2.497	2.445e-02	0.461	-3.423	CD83	CD83 molecule	6	14225843	NM_004233	9308	6p23	Hs.595133	44	plasma membrane integral to plasma membrane defense response humoral immune response signal transduction external side of plasma membrane response to organic cyclic substance negative regulation of interleukin-4 production positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of CD4-positive, alpha beta T cell differentiation
204077_x_at	0.208	5.433	2.497	2.445e-02	0.461	-3.423	ENTPD4	ectonucleoside triphosphate diphosphohydrolase 4	8	-23345516, -23345516	NM_004901	9583	8p21.3-p21.2	Hs.444389	8	magnesium ion binding calcium ion binding Golgi apparatus UDP catabolic process membrane integral to membrane hydrolase activity integral to Golgi membrane cytoplasmic vesicle uridine-diphosphatase activity	Purine metabolism Pyrimidine metabolism Lysosome
225477_s_at	-0.314	7.335	-2.497	2.445e-02	0.461	-3.423	NR2C2	nuclear receptor subfamily 2, group C, member 2	3	14964239	AL138444	7182	3p25	Hs.555973	22	transcription factor activity steroid hormone receptor activity transcription coactivator activity nucleus nucleolus regulation of transcription, DNA-dependent nervous system development zinc ion binding sequence-specific DNA binding metal ion binding spermatocyte division
229113_s_at	0.340	5.894	2.497	2.448e-02	0.461	-3.424	C1orf86	chromosome 1 open reading frame 86	1	-2110847	W16779	199990	1p36.33	Hs.107101 Hs.719244	5
203409_at	0.289	5.218	2.497	2.448e-02	0.461	-3.424	DDB2	damage-specific DNA binding protein 2, 48kDa	11	47193068	NM_000107	1643	11p12-p11	Hs.700338	52	protein polyubiquitination nucleotide-excision repair, DNA damage removal damaged DNA binding ubiquitin-protein ligase activity protein binding nucleus nucleoplasm pyrimidine dimer repair response to DNA damage stimulus response to UV modification-dependent protein catabolic process protein complex protein autoubiquitination	Nucleotide excision repair p53 signaling pathway Ubiquitin mediated proteolysis
1567270_at	-0.234	4.108	-2.497	2.448e-02	0.461	-3.424	OR4C1P	olfactory receptor, family 4, subfamily C, member 1 pseudogene	11		X64985	26242	11q11	Hs.550274	1
219219_at	0.321	7.029	2.496	2.450e-02	0.462	-3.425	TMEM160	transmembrane protein 160	19	-52241006	NM_017854	54958	19q13.32	Hs.105606	3	membrane integral to membrane
1565661_x_at	0.275	5.480	2.496	2.450e-02	0.462	-3.425	FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	19	-5781636	BC040472	2528	19p13.3	Hs.631846 Hs.705615	19	Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
218188_s_at	-0.298	8.185	-2.496	2.452e-02	0.462	-3.425	TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)	19	-2376621	NM_012458	26517	19p13.3	Hs.75056	16	protein binding mitochondrion mitochondrial inner membrane presequence translocase complex sensory perception of sound zinc ion binding protein transport membrane mitochondrial intermembrane space protein transporter complex protein import into mitochondrial inner membrane metal ion binding intracellular protein transmembrane transport
32042_at	-0.233	4.272	-2.496	2.453e-02	0.462	-3.426	ENOX2	ecto-NOX disulfide-thiol exchanger 2	X	-129585037	S72904	10495	Xq25-q26.2	Hs.171458	22	nucleotide binding nucleic acid binding copper ion binding extracellular region extracellular space nucleus cytoplasm cytosol cytoskeleton plasma membrane transport ultradian rhythm external side of plasma membrane protein disulfide oxidoreductase activity cell growth oxidoreductase activity electron transport chain regulation of growth
221516_s_at	0.208	7.080	2.494	2.459e-02	0.462	-3.428	SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	22	38228229	BC002587	54471	22q13	Hs.718449	11	mitochondrion membrane integral to membrane
209604_s_at	0.292	5.927	2.494	2.459e-02	0.462	-3.428	GATA3	GATA binding protein 3	10	8136672	BC003070	2625	10p15	Hs.524134	92	transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter defense response transcription factor binding zinc ion binding anatomical structure morphogenesis sequence-specific DNA binding response to estrogen stimulus metal ion binding
227994_x_at	0.445	8.313	2.494	2.459e-02	0.462	-3.428	PPDPF	pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)	20	61622576	AA548838	79144	20q13.33	Hs.79625	3	multicellular organismal development cell differentiation
223339_at	0.331	7.497	2.494	2.463e-02	0.462	-3.429	ATPIF1	ATPase inhibitory factor 1	1	28435197	BC001867	93974		Hs.590908	13	angiogenesis negative regulation of endothelial cell proliferation calmodulin binding mitochondrion mitochondrion mitochondrial proton-transporting ATP synthase complex generation of precursor metabolites and energy cell surface ATPase inhibitor activity ATPase inhibitor activity protein homodimerization activity angiostatin binding negative regulation of nucleotide metabolic process ATPase binding ATPase binding protein homotetramerization negative regulation of hydrolase activity negative regulation of hydrolase activity
228318_s_at	0.363	6.745	2.493	2.464e-02	0.462	-3.430	CRIPAK	cysteine-rich PAK1 inhibitor	4	1375339	AI356283	285464	4p16.3	Hs.26410	3	protein binding nucleus cytoplasm endoplasmic reticulum plasma membrane negative regulation of protein kinase activity ER-nuclear signaling pathway response to estrogen stimulus regulation of cytoskeleton organization
230737_s_at	0.217	4.357	2.493	2.465e-02	0.463	-3.430	LOC387647	patched domain containing 3 pseudogene	10	29738506	AW118878	387647	10p11.23	Hs.719271	2
204431_at	-0.248	6.607	-2.493	2.468e-02	0.463	-3.431	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	19	-2948636, -2948636, -2948636	NM_003260	7089	19p13.3	Hs.332173	15	protein binding nucleus signal transduction organ morphogenesis Wnt receptor signaling pathway regulation of transcription
226029_at	0.280	4.077	2.493	2.468e-02	0.463	-3.431	VANGL2	vang-like 2 (van gogh, Drosophila)	1	158636990	AB033041	57216	1q22-q23	Hs.99477	8	establishment of planar polarity neural tube closure heart looping multicellular organismal development membrane integral to membrane sensory cilium assembly apical protein localization	Wnt signaling pathway
209896_s_at	-0.790	6.546	-2.492	2.468e-02	0.463	-3.431	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	AF119855	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
210791_s_at	-0.357	5.020	-2.492	2.470e-02	0.463	-3.432	RICS	Rho GTPase-activating protein	11	-128340165, -128340165	BC000277	9743	11q24-q25	Hs.440379	17	Golgi membrane GTPase activator activity protein binding intracellular cytoplasm endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus plasma membrane cell cortex signal transduction endosome membrane postsynaptic density cell junction phosphoinositide binding cell projection dendritic spine synapse postsynaptic membrane
210828_s_at	-0.190	4.339	-2.492	2.472e-02	0.463	-3.433	ARNT	aryl hydrocarbon receptor nuclear translocator	1	-149048809	AF001307	405	1q21	Hs.632446	88	response to hypoxia positive regulation of endothelial cell proliferation RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus regulation of transcription, DNA-dependent signal transduction positive regulation vascular endothelial growth factor production aryl hydrocarbon receptor binding positive regulation of vascular endothelial growth factor receptor signaling pathway mRNA transcription from RNA polymerase II promoter positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of glycolysis positive regulation of hormone biosynthetic process protein heterodimerization activity	Pathways in cancer Renal cell carcinoma
203244_at	-0.275	8.432	-2.491	2.474e-02	0.463	-3.433	PEX5	peroxisomal biogenesis factor 5	12	7233025, 7233548, 7234224	NM_000319	5830	12p13.31	Hs.567327	45	protein binding cytoplasm peroxisome protein transport membrane
215529_x_at	0.259	7.376	2.490	2.479e-02	0.464	-3.435	DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	21	46703289, 46703289, 46703289, 46703289, 46703289	AI590053	23181	21q22.3	Hs.189585	11	catalytic activity nucleus multicellular organismal development transcription factor binding metabolic process
219520_s_at	0.247	7.080	2.490	2.481e-02	0.464	-3.436	WWC3	WWC family member 3	X	9943794	NM_018458	55841	Xp22.32	Hs.527524	5
1561042_at	0.463	4.227	2.490	2.482e-02	0.464	-3.436	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	AF086249	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
203761_at	0.329	5.123	2.490	2.482e-02	0.464	-3.436	SLA	Src-like-adaptor	8	-134118154, -134118154	NM_006748	6503	8q22.3-qter 8q24	Hs.75367	15	SH3/SH2 adaptor activity protein binding cytoplasm endosome
213548_s_at	-0.347	3.981	-2.489	2.485e-02	0.464	-3.437	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	BG257762	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
223585_x_at	-0.592	5.827	-2.488	2.489e-02	0.465	-3.438	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	7	-32874302	AF151831	25948	7p14.3	Hs.372541	4	protein binding
213570_at	0.252	5.014	2.488	2.492e-02	0.465	-3.440	EIF4E2	eukaryotic translation initiation factor 4E family member 2	2	233123600	BF516289	9470	2q37.1	Hs.292026 Hs.700929	15	RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation	mTOR signaling pathway Insulin signaling pathway
208640_at	-0.272	10.558	-2.487	2.495e-02	0.465	-3.441	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	BG292367	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
1567458_s_at	-0.573	7.595	-2.487	2.498e-02	0.465	-3.442	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	AJ012502	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
1557642_at	0.191	2.092	2.486	2.498e-02	0.465	-3.442	LOC100129258	hypothetical protein LOC100129258	2		AK090907	100129258	2q37.2	Hs.591594	1
202747_s_at	0.346	8.325	2.486	2.499e-02	0.465	-3.442	ITM2A	integral membrane protein 2A	X	-78502536	NM_004867	9452	Xq13.3-Xq21.2	Hs.17109 Hs.694944	14	cytoplasm plasma membrane integral to membrane
1552727_s_at	0.425	3.998	2.486	2.499e-02	0.465	-3.442	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	15	-98329165	AA022668	170691	15q24	Hs.513200	5	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
241393_at	0.312	6.009	2.486	2.500e-02	0.465	-3.442	IPP	intracisternal A particle-promoted polypeptide	1	-45936995, -45932586	R78604	3652	1p34-p32	Hs.699548	8	actin binding protein binding cytoplasm actin cytoskeleton
219060_at	0.343	7.382	2.486	2.501e-02	0.465	-3.443	WDYHV1	WDYHV motif containing 1	8	124498145	NM_018024	55093	8q24.13	Hs.18029	7	protein binding nucleus cytosol protein modification process protein N-terminal glutamine amidohydrolase activity
205332_at	-0.213	5.443	-2.486	2.502e-02	0.465	-3.443	RCE1	RCE1 homolog, prenyl protein peptidase (S. cerevisiae)	11	66367458	AF121951	9986	11q13	Hs.654972	9	metalloendopeptidase activity endoplasmic reticulum integral to plasma membrane proteolysis membrane hydrolase activity
202948_at	0.402	5.509	2.486	2.503e-02	0.465	-3.443	IL1R1	interleukin 1 receptor, type I	2	102136833	NM_000877	3554	2q12	Hs.701982	160	transmembrane receptor activity interleukin-1, Type I, activating receptor activity platelet-derived growth factor receptor binding protein binding integral to plasma membrane cell surface receptor linked signal transduction membrane innate immune response interleukin-1-mediated signaling pathway response to interleukin-1	MAPK signaling pathway Cytokine-cytokine receptor interaction Apoptosis Hematopoietic cell lineage
212237_at	-0.351	6.826	-2.485	2.503e-02	0.465	-3.444	ASXL1	additional sex combs like 1 (Drosophila)	20	30409813	N64780	171023	20q11.1	Hs.374043	13	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
230409_at	0.238	4.023	2.484	2.508e-02	0.466	-3.445	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	1	113734997, 113734997	AI738585	260425	1p12-p11.2	Hs.486189	13	nucleotide binding protein binding ATP binding nucleus plasma membrane tight junction cell junction interspecies interaction between organisms	Tight junction
203740_at	0.362	7.753	2.484	2.512e-02	0.466	-3.446	MPHOSPH6	M-phase phosphoprotein 6	16	-80739267	NM_005792	10200	16q23.3	Hs.344400	11	M phase of mitotic cell cycle protein binding nucleus nucleolus cytoplasm	RNA degradation
226140_s_at	-1.136	7.548	-2.484	2.512e-02	0.466	-3.447	OTUD1	OTU domain containing 1	10	23768203	AI934347	220213	10p12.2	Hs.499042	4
205357_s_at	-0.315	6.117	-2.483	2.516e-02	0.466	-3.448	AGTR1	angiotensin II receptor, type 1	3	149898347, 149930656	NM_000685	185	3q21-q25	Hs.477887 Hs.719071	524	regulation of cell growth angiotensin type I receptor activity angiotensin type I receptor activity kidney development renin-angiotensin regulation of aldosterone production regulation of blood vessel size by renin-angiotensin regulation of natriuresis receptor activity G-protein coupled receptor activity angiotensin type II receptor activity plasma membrane integral to plasma membrane oxygen and reactive oxygen species metabolic process signal transduction acetyltransferase activator activity positive regulation of foam cell differentiation positive regulation of cholesterol esterification regulation of vasoconstriction regulation of vasoconstriction regulation of vasoconstriction calcium-mediated signaling bradykinin receptor binding positive regulation of cellular protein metabolic process positive regulation of phospholipase A2 activity positive regulation of NAD(P)H oxidase activity low-density lipoprotein particle remodeling regulation of cell proliferation regulation of vasodilation protein heterodimerization activity positive regulation of inflammatory response elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction Renin-angiotensin system
233558_s_at	-0.440	5.746	-2.482	2.519e-02	0.466	-3.449	C4orf41	chromosome 4 open reading frame 41	4	184817439	AK023390	60684	4q35.1	Hs.443240	6
201588_at	-0.192	10.440	-2.482	2.520e-02	0.466	-3.449	TXNL1	thioredoxin-like 1	18	-52421050	NM_004786	9352	18q21.31	Hs.114412	15	cytoplasm transport disulfide oxidoreductase activity electron transport chain cell redox homeostasis
237515_at	-0.932	6.341	-2.482	2.521e-02	0.466	-3.450	TMEM56	transmembrane protein 56	1	95355481	AA054642	148534	1p21.3	Hs.483512	3	molecular_function cellular_component biological_process membrane integral to membrane
210805_x_at	-0.186	3.581	-2.482	2.522e-02	0.466	-3.450	RUNX1	runt-related transcription factor 1	21	-35115443, -35081967, -35081967	U19601	861	21q22.3	Hs.149261 Hs.612648	256	transcription factor activity protein binding ATP binding nucleus nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity positive regulation of granulocyte differentiation chloride ion binding positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter	Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia
203095_at	-0.300	8.767	-2.481	2.524e-02	0.466	-3.451	MTIF2	mitochondrial translational initiation factor 2	2	-55317259, -55317259	NM_002453	4528	2p14-p16	Hs.149894	10	nucleotide binding translation initiation factor activity GTPase activity GTP binding intracellular mitochondrion regulation of translational initiation ribosomal small subunit binding
209847_at	0.423	4.730	2.481	2.524e-02	0.466	-3.451	CDH17	cadherin 17, LI cadherin (liver-intestine)	8	-95208569, -95208569	U07969	1015	8q22.1	Hs.591853	20	transporter activity proton-dependent oligopeptide secondary active transmembrane transporter activity calcium ion binding protein binding plasma membrane transport oligopeptide transport cell adhesion homophilic cell adhesion integral to membrane basolateral plasma membrane calcium-dependent cell-cell adhesion
213392_at	-0.289	6.354	-2.481	2.524e-02	0.466	-3.451	IQCK	IQ motif containing K	16	19635278	AW070229	124152	16p12.3	Hs.460217	6
203821_at	-0.416	7.604	-2.481	2.524e-02	0.466	-3.451	HBEGF	heparin-binding EGF-like growth factor	5	-139692611	NM_001945	1839	5q23	Hs.592942 Hs.799	98	receptor activity epidermal growth factor receptor binding extracellular region extracellular space plasma membrane integral to plasma membrane signal transduction epidermal growth factor receptor signaling pathway muscle organ development regulation of heart contraction growth factor activity heparin binding cell surface wound healing, spreading of epidermal cells positive regulation of smooth muscle cell proliferation positive regulation of keratinocyte migration	ErbB signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection
231859_at	-0.269	4.943	-2.481	2.524e-02	0.466	-3.451	C14orf132	chromosome 14 open reading frame 132	14	95575414	AK025915	56967	14q32.2	Hs.6434	6	membrane integral to membrane
210820_x_at	-0.226	6.603	-2.481	2.526e-02	0.466	-3.451	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	16	18986427	AL136647	10229	16p13.11-p12.3	Hs.157113	18	iron ion binding nucleus mitochondrion ubiquinone biosynthetic process oxidoreductase activity protein metabolic process	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
212646_at	-0.530	8.576	-2.481	2.527e-02	0.466	-3.452	RFTN1	raftlin, lipid raft linker 1	3	-16332355	D42043	23180	3p25.1-p24.3	Hs.98910	6	plasma membrane
242224_at	-0.228	3.122	-2.481	2.527e-02	0.466	-3.452	GPATCH2	G patch domain containing 2	1	-215670456	R40111	55105	1q41	Hs.420757	6	nucleic acid binding intracellular
203323_at	0.482	7.788	2.481	2.527e-02	0.466	-3.452	CAV2	caveolin 2	7	115926679	BF197655	858	7q31.1	Hs.212332 Hs.603096	50	negative regulation of endothelial cell proliferation protein binding intracellular Golgi apparatus plasma membrane integral to plasma membrane caveola vesicle fusion mitochondrion organization endoplasmic reticulum organization transport vesicle protein homodimerization activity vesicle docking perinuclear region of cytoplasm skeletal muscle fiber development protein oligomerization	Focal adhesion
223548_at	-0.245	5.383	-2.480	2.528e-02	0.466	-3.452	C1orf26	chromosome 1 open reading frame 26	1	183392814, 183392913	AF288392	54823	1q25	Hs.134183	8
202844_s_at	-0.258	7.653	-2.480	2.529e-02	0.466	-3.453	RALBP1	ralA binding protein 1	18	9465529	AW025261	10928	18p11.3	Hs.528993 Hs.719181	42	GTPase activator activity protein binding intracellular transport chemotaxis signal transduction small GTPase mediated signal transduction membrane ATPase activity Ral GTPase binding Rac GTPase activator activity regulation of GTPase activity positive regulation of Cdc42 GTPase activity ATPase activity, coupled to movement of substances Rac GTPase binding	Pathways in cancer Pancreatic cancer
209905_at	0.360	7.543	2.480	2.531e-02	0.466	-3.453	HOXA9	homeobox A9	7	-27168581	AI246769	3205	7p15-p14	Hs.659350	63	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity sequence-specific DNA binding
214505_s_at	-0.673	12.494	-2.480	2.531e-02	0.466	-3.453	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF220153	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
1564263_at	0.196	4.838	2.480	2.532e-02	0.466	-3.454	LOC144817	hypothetical protein LOC144817	13		AK056732	144817	13q14.11	Hs.585616	1
200934_at	-0.599	9.031	-2.479	2.534e-02	0.466	-3.454	DEK	DEK oncogene	6	-18332380, -18332378	NM_003472	7913	6p22.3	Hs.484813	55	DNA binding specific RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter signal transduction viral genome replication histone binding
211742_s_at	0.236	4.255	2.479	2.535e-02	0.466	-3.455	EVI2B	ecotropic viral integration site 2B	17	-26654913	BC005926	2124	17q11.2	Hs.5509	10	cytoplasm integral to plasma membrane membrane
209055_s_at	-0.449	6.170	-2.479	2.538e-02	0.466	-3.456	CDC5L	CDC5 cell division cycle 5-like (S. pombe)	6	44463279	AW268817	988	6p21	Hs.485471	35	DNA binding RNA binding protein binding nucleus spliceosomal complex nucleolus cytoplasm regulation of transcription, DNA-dependent mRNA processing cell cycle RNA splicing nuclear speck
234685_x_at	0.253	3.300	2.478	2.542e-02	0.466	-3.457	KRTAP4-9	keratin associated protein 4-9	17	36515166	AJ406941	100132386	17q21.2	Hs.307018 Hs.711926	1	keratin filament
235577_at	0.518	4.843	2.478	2.542e-02	0.466	-3.457	ZNF652	zinc finger protein 652	17	-44721567, -44721567	AL036451	22834	17q21.32-q21.33	Hs.463375	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
223424_s_at	-0.271	6.552	-2.477	2.544e-02	0.467	-3.458	ZSCAN21	zinc finger and SCAN domain containing 21	7	99485352	AL136865	7589	7q22.1	Hs.632294	9	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription activator activity metal ion binding
223445_at	-0.382	6.676	-2.477	2.545e-02	0.467	-3.458	DTNBP1	dystrobrevin binding protein 1	6	-15631784, -15631017	AF061734	84062	6p22.3	Hs.571148	99	nucleus organelle organization blood coagulation visual perception sarcoplasm axon sarcolemma identical protein binding response to stimulus platelet dense granule organization
1556325_at	-0.461	8.240	-2.477	2.547e-02	0.467	-3.459	FILIP1	filamin A interacting protein 1	6	-76074519	AL832009	27145	6q14.1	Hs.696158	9
226312_at	-0.342	7.938	-2.477	2.548e-02	0.467	-3.459	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	BF940270	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
223598_at	-0.400	9.548	-2.476	2.548e-02	0.467	-3.459	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	AF262027	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
220588_at	0.228	3.931	2.476	2.550e-02	0.467	-3.460	BCAS4	breast carcinoma amplified sequence 4	20	48844873	NM_017843	55653	20q13.13	Hs.708239	6	cytoplasm
201828_x_at	0.365	9.276	2.475	2.554e-02	0.467	-3.461	FAM127A	family with sequence similarity 127, member A	X	133993998	NM_003928	8933	Xq26	Hs.522789	9
230611_at	-0.286	9.547	-2.475	2.558e-02	0.468	-3.462	SYPL2	synaptophysin-like 2	1	109810622	AW271199	284612	1p13.3	Hs.528366	5	transporter activity transport synaptic vesicle membrane integral to membrane
1553284_s_at	0.185	3.227	2.474	2.559e-02	0.468	-3.463	LMLN	leishmanolysin-like (metallopeptidase M8 family)	3	199171467	NM_033029	89782	3q29	Hs.518540	2	metalloendopeptidase activity cytoplasm proteolysis cell cycle mitosis cell adhesion peptidase activity zinc ion binding membrane metal ion binding cell division
225157_at	-0.409	9.347	-2.474	2.561e-02	0.468	-3.464	MLXIP	MLX interacting protein	12	121001142	AW245631	22877	12q24.31	Hs.437153	7	DNA binding nucleus cytoplasm mitochondrion mitochondrial outer membrane membrane transcription regulator activity regulation of transcription
207728_at	0.226	3.829	2.473	2.563e-02	0.468	-3.464	ATF7IP	activating transcription factor 7 interacting protein	12	14409877	NM_018005	55729	12p13.1	Hs.714407	17	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding nucleus transcription factor complex cytoplasm DNA methylation ATPase activity interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent regulation of transcriptional preinitiation complex assembly
202090_s_at	0.216	11.887	2.473	2.563e-02	0.468	-3.464	UQCR	ubiquinol-cytochrome c reductase, 6.4kDa subunit	19	-1548170	NM_006830	10975	19p13.3	Hs.8372	4	mitochondrion mitochondrial inner membrane mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity electron carrier activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
1569348_at	-0.414	4.238	-2.473	2.564e-02	0.468	-3.465	psiTPTE22	TPTE pseudogene	22	15462800	BC017420	387590	22q11.1	Hs.474116	4
219789_at	-0.574	4.206	-2.472	2.569e-02	0.469	-3.466	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	5	32747421	AI628360	4883	5p14-p13	Hs.237028 Hs.619466	27	skeletal system development receptor activity membrane fraction inhibition of adenylate cyclase activity by G-protein signaling activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger regulation of blood pressure peptide receptor activity, G-protein coupled membrane integral to membrane natriuretic peptide receptor activity peptide hormone binding chloride ion binding protein homodimerization activity
200738_s_at	-0.450	11.446	-2.472	2.570e-02	0.469	-3.467	PGK1	phosphoglycerate kinase 1	X	77246321	NM_000291	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
1552978_a_at	-0.580	5.549	-2.472	2.571e-02	0.469	-3.467	SCAMP1	secretory carrier membrane protein 1	5	77692094	NM_052822	9522	5q13.3-q14.1	Hs.482587	22	protein binding endosome Golgi apparatus trans-Golgi network post-Golgi vesicle-mediated transport protein transport membrane integral to membrane recycling endosome membrane
220259_at	0.208	3.264	2.471	2.574e-02	0.469	-3.468	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	17	-38073458	NM_024927	79990	17q21.2	Hs.632251	2	cytoskeleton
232489_at	0.385	5.732	2.471	2.575e-02	0.469	-3.468	CCDC76	coiled-coil domain containing 76	1	100371293	AK001149	54482	1pter-q31.3	Hs.440371	5	tRNA processing methyltransferase activity zinc ion binding transferase activity metal ion binding
225210_s_at	-0.332	8.367	-2.470	2.579e-02	0.469	-3.470	FAM103A1	family with sequence similarity 103, member A1	15	81445998	AW025216	83640	15q25.2	Hs.80624	3
214927_at	0.395	5.737	2.470	2.581e-02	0.470	-3.470	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	13	100902966	AL359052	9358	13q33	Hs.696554	5	receptor activity binding extracellular region cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex
1561281_a_at	0.222	3.189	2.469	2.584e-02	0.470	-3.471	LOC284576	hypothetical protein LOC284576	1		AK090497	284576	1q32.1	Hs.585440	1
201075_s_at	-0.314	5.226	-2.469	2.586e-02	0.470	-3.472	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	3	-47602381	NM_003074	6599	3p23-p21	Hs.476179	39	chromatin DNA binding chromatin binding transcription coactivator activity intracellular nucleus nucleoplasm chromatin assembly or disassembly chromatin remodeling regulation of transcription from RNA polymerase II promoter protein C-terminus binding organ morphogenesis SWI/SNF complex regulation of transcription positive regulation of transcription, DNA-dependent protein N-terminus binding
225154_at	-0.204	8.403	-2.469	2.586e-02	0.470	-3.472	SYAP1	synapse associated protein 1, SAP47 homolog (Drosophila)	X	16647675	BG029566	94056	Xp22.2	Hs.605178	11	nucleus
223611_s_at	0.513	5.929	2.468	2.589e-02	0.470	-3.473	LNX1	ligand of numb-protein X 1	4	-54021193, -54021193	AI738919	84708	4q12	Hs.518760 Hs.624833	22	ubiquitin-protein ligase activity protein binding cytoplasm zinc ion binding ligase activity PDZ domain binding protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding protein homooligomerization
222847_s_at	-0.302	5.277	-2.468	2.590e-02	0.470	-3.473	EGLN3	egl nine homolog 3 (C. elegans)	14	-33463171	AI378406	112399	14q13.1	Hs.135507	26	iron ion binding protein binding nucleus cytoplasm apoptosis oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
226612_at	-0.552	8.605	-2.468	2.590e-02	0.470	-3.473	FLJ25076	probable ubiquitin-conjugating enzyme E2 FLJ25076	5	6501735	H17038	134111	5p15.31	Hs.126856	3	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
224355_s_at	0.367	5.409	2.468	2.592e-02	0.470	-3.474	MS4A8B	membrane-spanning 4-domains, subfamily A, member 8B	11	60223622	AF237905	83661	11q12.2	Hs.150878	5	receptor activity signal transduction membrane integral to membrane
222589_at	-0.308	6.459	-2.468	2.593e-02	0.470	-3.474	NLK	nemo-like kinase	17	23393814	AI967933	51701	17q11.2	Hs.208759	24	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase activity ATP binding nucleus nucleolus cytoplasm transforming growth factor beta receptor signaling pathway protein kinase cascade transcription factor binding transferase activity peptidyl-threonine phosphorylation negative regulation of Wnt receptor signaling pathway ubiquitin protein ligase binding serine phosphorylation of STAT3 protein SH2 domain binding regulation of transcription protein amino acid autophosphorylation	MAPK signaling pathway Wnt signaling pathway Adherens junction
205032_at	-0.182	4.910	-2.467	2.595e-02	0.470	-3.475	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	5	52320912	NM_002203	3673	5q23-q31	Hs.482077	235	magnesium ion binding receptor activity calcium ion binding collagen binding plasma membrane plasma membrane cell adhesion cell-matrix adhesion integrin-mediated signaling pathway blood coagulation integrin complex organ morphogenesis external side of plasma membrane integral to membrane identical protein binding interspecies interaction between organisms	Focal adhesion ECM-receptor interaction Hematopoietic cell lineage Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1554514_at	-0.259	3.375	-2.467	2.595e-02	0.470	-3.475	ACSM5	acyl-CoA synthetase medium-chain family member 5	16	20328356	BC013753	54988	16p12.3	Hs.659606	3	nucleotide binding magnesium ion binding ATP binding GTP binding mitochondrion mitochondrial matrix lipid metabolic process fatty acid metabolic process metabolic process ligase activity butyrate-CoA ligase activity	Butanoate metabolism Metabolic pathways
226804_at	0.285	4.386	2.467	2.597e-02	0.470	-3.476	FAM20A	family with sequence similarity 20, member A	17	-64042852, -64042852	AI632223	54757	17q24.2	Hs.268874	5	extracellular region
215464_s_at	0.330	6.211	2.467	2.597e-02	0.470	-3.476	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	17	-3512937	AK001327	30851	17p13	Hs.12956	14	nucleus cytoplasm Rho protein signal transduction beta-catenin binding negative regulation of cell proliferation negative regulation of Wnt receptor signaling pathway transcription regulator activity
212728_at	0.253	4.844	2.466	2.599e-02	0.470	-3.476	DLG3	discs, large homolog 3 (Drosophila)	X	69581448, 69588885	T62872	1741	Xq13.1	Hs.716481	39	guanylate kinase activity protein binding cellular_component negative regulation of cell proliferation
228471_at	0.386	4.707	2.466	2.604e-02	0.470	-3.478	ANKRD44	ankyrin repeat domain 44	2	-197567494	AA744636	91526	2q33.1	Hs.654819	6	protein binding
201288_at	0.393	7.825	2.465	2.606e-02	0.470	-3.479	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	12	-14986216	NM_001175	397	12p12.3	Hs.504877	34	Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding cytoplasm cytoskeleton cell motion immune response negative regulation of cell adhesion Rho protein signal transduction multicellular organismal development cytoplasmic membrane-bounded vesicle actin cytoskeleton organization	Neurotrophin signaling pathway
207284_s_at	-0.393	6.962	-2.465	2.607e-02	0.470	-3.479	ASPH	aspartate beta-hydroxylase	8	-62739837, -62699648, -62699648, -62575669	NM_020164	444	8q12.1	Hs.591874	24	peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis
1555420_a_at	-0.316	4.324	-2.465	2.608e-02	0.470	-3.480	KLF7	Kruppel-like factor 7 (ubiquitous)	2	-207653773	BC012919	8609	2q32	Hs.471221	9	transcription factor activity transcription coactivator activity intracellular nucleus regulation of transcription from RNA polymerase II promoter axon guidance zinc ion binding regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding dendrite morphogenesis
202166_s_at	-0.518	9.095	-2.464	2.610e-02	0.470	-3.480	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	3	-196722511	NM_006241	5504	3q29	Hs.535731 Hs.706920	22	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy regulation of signal transduction regulation of phosphoprotein phosphatase activity
202071_at	-0.851	7.771	-2.464	2.612e-02	0.471	-3.481	SDC4	syndecan 4	20	-43387342	NM_002999	6385	20q12	Hs.632267	60	molecular_function Golgi apparatus plasma membrane integral to plasma membrane cytoskeletal protein binding biological_process cell surface thrombospondin receptor activity	ECM-receptor interaction Cell adhesion molecules (CAMs)
1554670_at	0.324	4.048	2.463	2.615e-02	0.471	-3.482	GGA1	golgi associated, gamma adaptin ear containing, ARF binding protein 1	22	36334448, 36334448	BC029388	26088	22q13.31	Hs.499158	50	molecular_function protein binding intracellular endosome intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex Golgi apparatus part	Lysosome
222421_at	-0.305	8.212	-2.463	2.618e-02	0.471	-3.483	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	7	-129260230	BF435617	7328	7q32	Hs.643548	16	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity regulation of protein metabolic process	Ubiquitin mediated proteolysis
223353_at	-0.238	7.134	-2.462	2.621e-02	0.471	-3.484	HCCA2	HCCA2 protein	11	-1447268	AB028173	81532	11p15.5	Hs.370360	6	protein binding nucleus cytoplasm zinc ion binding metal ion binding perinuclear region of cytoplasm
1552670_a_at	-0.914	6.455	-2.462	2.621e-02	0.471	-3.484	PPP1R3B	protein phosphatase 1, regulatory (inhibitor) subunit 3B	8	-9031176	NM_024607	79660	8p23.1	Hs.458513	7	carbohydrate metabolic process glycogen metabolic process	Insulin signaling pathway
220129_at	0.712	4.303	2.462	2.622e-02	0.471	-3.484	SOHLH2	spermatogenesis and oogenesis specific basic helix-loop-helix 2	13	-35640346	NM_017826	54937	13q13.3	Hs.124519	4	DNA binding nucleus multicellular organismal development spermatogenesis cell differentiation transcription regulator activity regulation of transcription oogenesis
209192_x_at	-0.246	6.558	-2.461	2.626e-02	0.472	-3.485	KAT5	K(lysine) acetyltransferase 5	11	65236064	BC000166	10524	11q13	Hs.397010	88	chromatin chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding nucleus nucleolus cytoplasm double-strand break repair chromatin assembly or disassembly DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator zinc ion binding acyltransferase activity chromatin modification histone acetylation transferase activity androgen receptor signaling pathway Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding perinuclear region of cytoplasm androgen receptor binding
1563632_at	-0.250	5.280	-2.461	2.626e-02	0.472	-3.485	LOC220980	hypothetical protein LOC220980	10		AK056518	220980	10q11.21	Hs.645270	1
227612_at	0.210	3.583	2.460	2.630e-02	0.472	-3.487	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	19	-11423142	R20763	1995	19p13.2	Hs.1701	8	nucleotide binding RNA binding multicellular organismal development nervous system development cell differentiation
213019_at	-0.283	7.854	-2.460	2.630e-02	0.472	-3.487	RANBP6	RAN binding protein 6	9	-6001019, -6001018	AI123233	26953	9p24.1	Hs.167496 Hs.675725	5	binding nucleus cytoplasm protein transport
1554728_at	0.188	3.408	2.460	2.630e-02	0.472	-3.487	SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	1	-27297887	BC012121	6548	1p36.1-p35	Hs.469116	86	response to acid membrane fraction cation transport sodium ion transport regulation of pH protein kinase cascade transcription factor binding response to acidity response to organic cyclic substance antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane cell growth basolateral plasma membrane cell differentiation sodium ion binding response to drug membrane raft positive regulation of anti-apoptosis	Cardiac muscle contraction Regulation of actin cytoskeleton
201364_s_at	-0.274	9.042	-2.460	2.635e-02	0.472	-3.488	OAZ2	ornithine decarboxylase antizyme 2	15	-62766825	AF242521	4947	15q22.31	Hs.713816 Hs.74563	9	protein binding polyamine metabolic process ornithine decarboxylase inhibitor activity
202254_at	0.508	4.103	2.459	2.639e-02	0.472	-3.490	SIPA1L1	signal-induced proliferation-associated 1 like 1	14	71065794	AB007900	26037	14q24.2	Hs.654657	14	molecular_function GTPase activator activity protein binding cellular_component intracellular biological_process regulation of small GTPase mediated signal transduction
235770_at	-0.543	3.252	-2.459	2.640e-02	0.472	-3.490	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	3	-188447299, -188434565, -188418631	AI023911	5648	3q27-q28	Hs.89983	30	complement activation, lectin pathway complement activation, lectin pathway serine-type endopeptidase activity calcium ion binding extracellular region extracellular region extracellular space proteolysis peptidase activity protein homodimerization activity calcium-dependent protein binding	Complement and coagulation cascades
225852_at	0.246	7.584	2.458	2.640e-02	0.472	-3.490	ANKRD17	ankyrin repeat domain 17	4	-74159365	BE463523	26057	4q13.3	Hs.644997 Hs.719092	10	RNA binding ATP binding nucleus cytoplasm mismatch repair mismatched DNA binding interspecies interaction between organisms
211581_x_at	0.320	5.299	2.458	2.641e-02	0.472	-3.491	LST1	leukocyte specific transcript 1	6	31661949, 31662603, 3000093, 3000747, 2801557, 2802211	AF000426	7940	6p21.3	Hs.436066	20	cell morphogenesis molecular_function protein binding cytoplasm Golgi apparatus immune response regulation of cell shape anatomical structure morphogenesis membrane integral to membrane dendrite development negative regulation of lymphocyte proliferation
222130_s_at	-0.306	6.905	-2.458	2.644e-02	0.472	-3.491	FTSJ2	FtsJ homolog 2 (E. coli)	7	-2240451	AK024635	29960	7p22	Hs.279877	4	nucleic acid binding nucleus nucleolus rRNA processing RNA methyltransferase activity transferase activity rRNA methylation methylation
223175_s_at	-0.438	10.444	-2.458	2.645e-02	0.472	-3.492	FEM1A	fem-1 homolog a (C. elegans)	19	4742727	BC004988	55527	19p13.3	Hs.515082	9	ubiquitin-protein ligase activity cytoplasm modification-dependent protein catabolic process regulation of ubiquitin-protein ligase activity
229105_at	-0.224	3.149	-2.457	2.645e-02	0.472	-3.492	GPR39	G protein-coupled receptor 39	2	132890616	AV717094	2863	2q21-q22	Hs.432395 Hs.719231	14	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway zinc ion binding metal ion binding
226591_at	0.686	6.832	2.457	2.647e-02	0.472	-3.492	SNRPN	small nuclear ribonucleoprotein polypeptide N	15	22619886, 22652790, 22751227	BG413612	6638	15q11.2	Hs.555970 Hs.564847 Hs.578619 Hs.585703 Hs.592473 Hs.621316 Hs.632166	47	RNA binding nucleus spliceosomal complex RNA splicing small nuclear ribonucleoprotein complex identical protein binding
225999_at	-0.381	5.149	-2.457	2.647e-02	0.472	-3.492	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AI743612	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
227582_at	0.326	6.611	2.457	2.649e-02	0.472	-3.493	KLHDC9	kelch domain containing 9	1	159334777	AW079843	126823	1q23.3	Hs.507290	3
214751_at	0.489	4.058	2.457	2.650e-02	0.472	-3.493	ZNF468	zinc finger protein 468	19	-58033596	BE541042	90333	19q13.41	Hs.467223	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222394_at	-0.325	7.107	-2.457	2.650e-02	0.472	-3.493	PDCD6IP	programmed cell death 6 interacting protein	3	33815069, 33815069, 33845133	BG484789	10015	3p22.3	Hs.475896	65	protein binding cytoplasm centrosome cytosol apoptosis cell cycle protein transport melanosome interspecies interaction between organisms cell division	Endocytosis
225484_at	0.262	4.076	2.457	2.650e-02	0.472	-3.493	TSGA14	testis specific, 14	7	-129823610	AW157525	95681	7q32	Hs.368315	6	centrosome
209141_at	-0.553	9.966	-2.456	2.652e-02	0.472	-3.494	UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	17	-4119260	AW299555	7326	17p13.2 1q42	Hs.714345	12	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
221449_s_at	-0.572	8.152	-2.456	2.653e-02	0.472	-3.494	ITFG1	integrin alpha FG-GAP repeat containing 1	16	-45746798	NM_030790	81533	16q12.1	Hs.42217	5	protein binding extracellular region membrane integral to membrane
209677_at	-0.407	3.387	-2.456	2.653e-02	0.472	-3.494	PRKCI	protein kinase C, iota	3	171422913	L18964	5584	3q26.3	Hs.478199	91	polarisome nucleotide binding protein kinase C activity protein binding ATP binding phospholipid binding nucleus cytoplasm endosome cytosol protein amino acid phosphorylation protein targeting to membrane cytoskeleton organization actin filament organization intracellular signaling cascade zinc ion binding membrane membrane organization vesicle-mediated transport apical plasma membrane transferase activity diacylglycerol binding cellular response to insulin stimulus establishment of apical/basal cell polarity eye photoreceptor cell development establishment or maintenance of epithelial cell apical/basal polarity cell-cell junction organization positive regulation of glucose import metal ion binding secretion Golgi vesicle budding regulation of establishment of protein localization	Endocytosis Tight junction Insulin signaling pathway
204821_at	0.349	4.520	2.456	2.653e-02	0.472	-3.495	BTN3A3	butyrophilin, subfamily 3, member A3	6	26548741	NM_006994	10384	6p21.3	Hs.167741	9	membrane integral to membrane
205428_s_at	0.206	4.777	2.456	2.655e-02	0.472	-3.495	CALB2	calbindin 2	16	69950126, 69950126	NM_001740	794	16q22.2	Hs.106857	33	calcium ion binding gap junction
214473_x_at	0.267	6.323	2.455	2.657e-02	0.472	-3.496	PMS2L3	postmeiotic segregation increased 2-like 3	7	-74975005, -74975004	NM_005395	5387	7q11.23	Hs.406395 Hs.659871 Hs.661055	4	molecular_function nucleic acid binding ATP binding cellular_component intracellular regulation of transcription, DNA-dependent biological_process
207436_x_at	-0.267	7.983	-2.455	2.657e-02	0.472	-3.496	KIAA0894	KIAA0894 protein	10		NM_014896	22833	10q23.33		1
228525_at	-0.246	6.224	-2.455	2.658e-02	0.472	-3.496	LRP3	low density lipoprotein receptor-related protein 3	19	38377438	AL583533	4037	19q13.11	Hs.515340 Hs.715569	9	receptor activity coated pit receptor-mediated endocytosis membrane integral to membrane
223441_at	0.375	6.537	2.455	2.659e-02	0.472	-3.496	SLC17A5	solute carrier family 17 (anion/sugar transporter), member 5	6	-74359822	AK026921	26503	6q14-q15	Hs.597422	28	sugar:hydrogen symporter activity membrane fraction lysosomal membrane integral to plasma membrane transport anion transport symporter activity membrane	Lysosome
218484_at	0.324	6.248	2.455	2.660e-02	0.472	-3.497	NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	12	-55914952	NM_020142	56901	12q13.3	Hs.75069	5		Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
206668_s_at	-0.480	5.281	-2.454	2.663e-02	0.472	-3.498	SCAMP1	secretory carrier membrane protein 1	5	77692094	NM_004866	9522	5q13.3-q14.1	Hs.482587	22	protein binding endosome Golgi apparatus trans-Golgi network post-Golgi vesicle-mediated transport protein transport membrane integral to membrane recycling endosome membrane
212119_at	-0.236	10.984	-2.454	2.664e-02	0.472	-3.498	RHOQ	ras homolog gene family, member Q	2	46623370	BF670447	23433	2p21	Hs.709193	27	nucleotide binding GTPase activity profilin binding GTP binding intracellular cytoplasm actin filament plasma membrane GTP catabolic process small GTPase mediated signal transduction insulin receptor signaling pathway regulation of cell shape positive regulation of specific transcription from RNA polymerase II promoter cortical actin cytoskeleton organization GBD domain binding regulation of actin cytoskeleton organization membrane raft positive regulation of glucose import positive regulation of filopodium assembly regulation of establishment of protein localization	Insulin signaling pathway
1556736_at	0.199	4.380	2.454	2.664e-02	0.472	-3.498	LOC100129858	hypothetical protein LOC100129858	4		AK095554	100129858	4q31.1	Hs.660477	1
214278_s_at	-0.246	6.162	-2.454	2.665e-02	0.472	-3.498	NDRG2	NDRG family member 2	14	-20554761, -20554761	AI358939	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
209771_x_at	0.509	4.450	2.453	2.667e-02	0.472	-3.499	CD24	CD24 molecule	6	-19611913	AA761181	100133941	6q21	Hs.644105 Hs.694721	65	response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation leukocyte migration during inflammatory response immune response-regulating cell surface receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptosis signal transducer activity protein binding membrane fraction plasma membrane oxygen and reactive oxygen species metabolic process heterophilic cell adhesion leukocyte adhesion elevation of cytosolic calcium ion concentration neuromuscular synaptic transmission negative regulation of neuroblast proliferation induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals apoptotic mitochondrial changes external side of plasma membrane Wnt receptor signaling pathway cell migration protein kinase binding carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity regulation of epithelial cell differentiation negative regulation of B cell proliferation neuron projection development anchored to membrane T cell costimulation anchored to external side of plasma membrane microvillus membrane B cell receptor transport into membrane raft chemokine receptor transport out of membrane raft negative regulation of transforming growth factor-beta3 production positive regulation of integrin activation positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPKKK cascade eukaryotic cell surface binding response to estrogen stimulus membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling cilium membrane
235645_at	-0.327	3.389	-2.453	2.668e-02	0.472	-3.499	ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)	18	-17363259	AW501507	114799	18q11.2	Hs.464733	8	damaged DNA binding DNA-directed DNA polymerase activity nucleus DNA repair cell cycle zinc ion binding acyltransferase activity transferase activity metal ion binding
206028_s_at	0.225	3.393	2.453	2.669e-02	0.472	-3.500	MERTK	c-mer proto-oncogene tyrosine kinase	2	112372661	NM_006343	10461	2q14.1	Hs.306178	32	nucleotide binding photoreceptor outer segment transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding soluble fraction integral to plasma membrane protein amino acid phosphorylation phagocytosis cell surface receptor linked signal transduction cell-cell signaling visual perception membrane transferase activity response to stimulus
1552887_at	-0.237	4.439	-2.453	2.669e-02	0.472	-3.500	C10orf27	chromosome 10 open reading frame 27	10	-72201000	NM_152710	219793	10q22.1	Hs.386698	5	protein binding cytoplasm cytosol multicellular organismal development spermatogenesis cell differentiation
1560665_at	0.204	4.500	2.453	2.670e-02	0.472	-3.500	SCPEP1	serine carboxypeptidase 1	17	52410466	AK092928	59342	17q22	Hs.514950	8	serine-type carboxypeptidase activity extracellular region proteolysis peptidase activity
1562799_at	0.224	5.444	2.453	2.670e-02	0.472	-3.500	LOC100130285	hypothetical LOC100130285	16		AK097604	100130285	16p13.3	Hs.683811	1
218499_at	0.264	2.665	2.453	2.670e-02	0.472	-3.500	RP6-213H19.1	serine/threonine protein kinase MST4	X	130984925, 130985316	NM_016542	51765	Xq26.2	Hs.444247	16	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus protein amino acid phosphorylation transferase activity identical protein binding regulation of apoptosis
236824_at	-0.192	2.615	-2.453	2.670e-02	0.472	-3.500	TMEM132B	transmembrane protein 132B	12	124377114	AI435595	114795	12q24.31-q24.32	Hs.524838	4	molecular_function cellular_component biological_process membrane integral to membrane
213126_at	-0.327	4.648	-2.453	2.671e-02	0.472	-3.500	MED8	mediator complex subunit 8	1	-43622983, -43622174	BG230758	112950	1p34.2	Hs.301756	12	nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity modification-dependent protein catabolic process regulation of transcription
223404_s_at	-0.356	7.473	-2.452	2.675e-02	0.472	-3.502	C1orf25	chromosome 1 open reading frame 25	1	-183353840	AW512122	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
200818_at	0.217	12.156	2.452	2.675e-02	0.472	-3.502	ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	21	-34197626	NM_001697	539	21q22.1-q22.2 21q22.11	Hs.409140	12	transporter activity mitochondrion mitochondrial proton-transporting ATP synthase complex mitochondrial proton-transporting ATP synthase complex plasma membrane ATP catabolic process ion transport drug binding proton transport ATPase activity mitochondrial ATP synthesis coupled proton transport proton-transporting ATP synthase complex, catalytic core F(1) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
212309_at	-0.367	8.706	-2.452	2.676e-02	0.472	-3.502	CLASP2	cytoplasmic linker associated protein 2	3	-33512741	AV725315	23122	3p22.3	Hs.108614	17	condensed chromosome kinetochore protein binding cytoplasm Golgi apparatus centrosome spindle kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity galactoside 2-alpha-L-fucosyltransferase activity regulation of microtubule polymerization or depolymerization microtubule plus-end binding cell division
206935_at	0.788	2.567	2.452	2.677e-02	0.472	-3.502	PCDH8	protocadherin 8	13	-52316109	NM_002590	5100	13q14.3-q21.1	Hs.19492	13	calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion cell-cell signaling
203179_at	0.266	7.076	2.451	2.681e-02	0.473	-3.504	GALT	galactose-1-phosphate uridylyltransferase	9	34636634	NM_000155	2592	9p13	Hs.522090	72	iron ion binding cytosol carbohydrate metabolic process galactose metabolic process UDP-glucose:hexose-1-phosphate uridylyltransferase activity UDP-glucose:hexose-1-phosphate uridylyltransferase activity zinc ion binding transferase activity nucleotidyltransferase activity metal ion binding	Galactose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
212166_at	-0.196	7.750	-2.451	2.682e-02	0.473	-3.504	XPO7	exportin 7	8	21833125, 21879694	H38643	23039	8p21	Hs.172685	9	protein import into nucleus, docking nuclear export signal receptor activity nucleus nuclear pore cytoplasm protein export from nucleus protein transporter activity mRNA transport intracellular protein transmembrane transport
216178_x_at	-0.593	7.325	-2.450	2.683e-02	0.473	-3.504	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	AA215854	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
221876_at	-0.170	6.368	-2.450	2.684e-02	0.473	-3.504	ZNF783	zinc finger family member 783	7	148590194	AU151157	155060	7q36.1	Hs.490512	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent
213880_at	-1.994	6.564	-2.450	2.685e-02	0.473	-3.505	LGR5	leucine-rich repeat-containing G protein-coupled receptor 5	12	70120079	AL524520	8549	12q22-q23	Hs.658889	16	receptor activity protein binding plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway protein-hormone receptor activity
227498_at	-0.736	7.987	-2.450	2.685e-02	0.473	-3.505	SOX6	SRY (sex determining region Y)-box 6	11	-15944571, -15944571, -15944571	AI480314	55553	11p15.3	Hs.368226	24	transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent multicellular organismal development muscle organ development
204631_at	-0.655	13.478	-2.450	2.687e-02	0.473	-3.506	MYH2	myosin, heavy chain 2, skeletal muscle, adult	17	-10365189, -10365189	NM_017534	4620	17p13.1	Hs.699445	22	microfilament motor activity nucleotide binding actin binding calmodulin binding ATP binding nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction structural constituent of muscle myosin complex muscle filament sliding	Tight junction
242201_at	0.467	5.241	2.449	2.692e-02	0.474	-3.507	PMS2L5	postmeiotic segregation increased 2-like 5	7	73944829, 73944829	AI418253	5383	7q11-q22	Hs.292996 Hs.647025	4	ATP binding mismatch repair mismatched DNA binding
224692_at	-0.495	6.812	-2.448	2.693e-02	0.474	-3.508	PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	1	-202639114	BF796046	84919	1q32.1	Hs.304376	6	protein phosphatase type 1 complex protein serine/threonine phosphatase activity regulation of translation response to oxidative stress ER overload response response to hydrogen peroxide
231816_s_at	0.237	4.612	2.448	2.695e-02	0.474	-3.508	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	1	-152787674	AI986085	55585	1q21.3	Hs.607928	7	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
228785_at	-0.314	7.557	-2.448	2.696e-02	0.474	-3.508	ZNF281	zinc finger protein 281	1	-198642042	AA121673	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
209498_at	0.252	5.401	2.447	2.700e-02	0.474	-3.510	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	X16354	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
1564544_x_at	-0.257	5.028	-2.447	2.701e-02	0.474	-3.510	LOC644450	hypothetical protein LOC644450	1		BC014871	644450	1q12	Hs.652926	1
223805_at	-0.382	8.468	-2.447	2.703e-02	0.474	-3.511	OSBPL6	oxysterol binding protein-like 6	2	178767619, 178893216	AF323728	114880	2q31-q32.1	Hs.318775	7	lipid transport steroid metabolic process
205551_at	0.397	5.273	2.446	2.704e-02	0.474	-3.511	SV2B	synaptic vesicle glycoprotein 2B	15	89570106	NM_014848	9899	15q26.1	Hs.21754	12	acrosomal vesicle transporter activity protein binding neurotransmitter transport synaptic vesicle membrane integral to membrane cell junction cytoplasmic vesicle synapse regulation of protein metabolic process	ECM-receptor interaction
218191_s_at	-0.423	8.686	-2.446	2.705e-02	0.474	-3.512	LMBRD1	LMBR1 domain containing 1	6	-70442469	NM_018368	55788	6q13	Hs.271643	9	lysosome transport membrane integral to membrane cobalamin binding interspecies interaction between organisms cobalt ion binding
232940_s_at	0.255	5.802	2.446	2.705e-02	0.474	-3.512	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	7	-151462942	AK025911	58508	7q36.1	Hs.647120	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent intracellular signaling cascade methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
239265_at	0.446	4.832	2.446	2.706e-02	0.474	-3.512	TMEM20	transmembrane protein 20	10	95643719	R56424	159371	10q23.33	Hs.632085	4	membrane integral to membrane
240114_s_at	0.244	5.303	2.445	2.710e-02	0.475	-3.513	TMEM174	transmembrane protein 174	5	72504778	AI927971	134288	5q13.2	Hs.508588	3	membrane integral to membrane
235388_at	-0.645	4.400	-2.445	2.710e-02	0.475	-3.513	CHD9	chromodomain helicase DNA binding protein 9	16	51646445	BG538482	80205	16q12.2	Hs.59159 Hs.622347	10	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription
216054_x_at	0.207	6.600	2.445	2.712e-02	0.475	-3.514	MYL4	myosin, light chain 4, alkali; atrial, embryonic	17	42641426, 42641712	X58851	4635	17q21-qter	Hs.463300	21	regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex muscle organ development structural constituent of muscle myosin complex A band myosin II heavy chain binding positive regulation of ATPase activity actin filament binding cardiac muscle contraction	Cardiac muscle contraction
227539_at	-0.615	5.704	-2.444	2.715e-02	0.475	-3.514	GNA13	guanine nucleotide binding protein (G protein), alpha 13	17	-60435870	AW298099	10672	17q24.3	Hs.515018	57	nucleotide binding patterning of blood vessels in utero embryonic development GTPase activity signal transducer activity protein binding GTP binding cell motion signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade Rho protein signal transduction regulation of cell shape membrane guanyl nucleotide binding cell differentiation platelet activation regulation of cell migration melanosome	Vascular smooth muscle contraction Long-term depression Regulation of actin cytoskeleton
214880_x_at	-0.300	6.284	-2.444	2.717e-02	0.476	-3.515	CALD1	caldesmon 1	7	134114710, 134226698	D90453	800	7q33	Hs.490203	40	actin binding calmodulin binding tropomyosin binding cytoskeleton plasma membrane cell motion muscle contraction myosin binding	Vascular smooth muscle contraction
207423_s_at	-0.275	4.376	-2.444	2.718e-02	0.476	-3.516	ADAM20	ADAM metallopeptidase domain 20	14	-70058830	AF029899	8748	14q24.1	Hs.177984	4	metalloendopeptidase activity proteolysis single fertilization peptidase activity zinc ion binding membrane integral to membrane metal ion binding
223821_s_at	0.299	3.157	2.444	2.719e-02	0.476	-3.516	SUSD4	sushi domain containing 4	1	-221474874, -221460783	BC004888	55061	1q41	Hs.497841	4	membrane integral to membrane
1555002_at	-0.187	1.909	-2.443	2.724e-02	0.476	-3.517	MGC39545	hypothetical protein LOC403312	11		BC036197	403312	11q24.2	Hs.450611	1
232124_at	0.267	3.430	2.443	2.724e-02	0.476	-3.518	LOC729085	hypothetical protein LOC729085	3	42995762	AL117530	729085	3p22.1	Hs.146346	2
201935_s_at	-0.572	7.842	-2.442	2.728e-02	0.476	-3.519	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	1	-21005560	AI768122	8672	1p36.12	Hs.467084	19	RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
219398_at	0.454	5.793	2.442	2.728e-02	0.476	-3.519	CIDEC	cell death-inducing DFFA-like effector c	3	-9883397	NM_022094	63924	3p25.3	Hs.567562 Hs.635072	6	molecular_function protein binding intracellular cytoplasm cytosol apoptosis induction of apoptosis
242098_at	0.188	2.490	2.442	2.729e-02	0.476	-3.519	LOC202451	hypothetical protein LOC202451	6		AW953116	202451	6q23.3	Hs.194408	1
221661_at	-0.220	3.784	-2.442	2.730e-02	0.476	-3.519	SLC22A7	solute carrier family 22 (organic anion transporter), member 7	6	43373975	AF210455	10864	6p21.2-p21.1	Hs.485438	10	membrane fraction plasma membrane integral to plasma membrane ion transport ion transmembrane transporter activity sodium-independent organic anion transmembrane transporter activity organic anion transport
221101_at	0.190	3.520	2.441	2.730e-02	0.476	-3.519	C14orf113	chromosome 14 open reading frame 113	14		NM_017630	54792	14q32.13	Hs.675410	1
202301_s_at	-0.415	7.267	-2.440	2.736e-02	0.476	-3.521	RSRC2	arginine/serine-rich coiled-coil 2	12	-121555225, -121555225	BE396879	65117	12q24.31	Hs.432996	4
219464_at	-0.566	7.403	-2.440	2.736e-02	0.476	-3.521	CA14	carbonic anhydrase XIV	1	148496841	NM_012113	23632	1q21	Hs.528988	11	carbonate dehydratase activity zinc ion binding membrane integral to membrane lyase activity metal ion binding	Nitrogen metabolism
242578_x_at	0.242	7.287	2.439	2.744e-02	0.477	-3.524	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3	6	160689414	AV699746	6581	6q26-q27	Hs.567337	33	transporter activity protein binding membrane fraction integral to plasma membrane ion transport ion transmembrane transporter activity quaternary ammonium group transmembrane transporter activity quaternary ammonium group transport monoamine transport membrane regulation of appetite histamine uptake
203013_at	-0.232	6.639	-2.438	2.748e-02	0.477	-3.525	ECD	ecdysoneless homolog (Drosophila)	10	-74564288	NM_007265	11319	10q22.1-q22.2	Hs.631822	11	transcription coactivator activity nucleus cytoplasm regulation of glycolysis transcription from RNA polymerase II promoter regulation of transcription
235389_at	-0.317	6.704	-2.438	2.748e-02	0.477	-3.525	PHF20	PHD finger protein 20	20	33823336	BG168139	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
211462_s_at	0.203	4.373	2.438	2.749e-02	0.477	-3.526	TBL1Y	transducin (beta)-like 1Y-linked	Y	6838726	AF332222	90665	Yp11.2	Hs.664560	5	chromatin binding protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter modification-dependent protein catabolic process regulation of transcription	Wnt signaling pathway
212761_at	0.245	7.824	2.438	2.749e-02	0.477	-3.526	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10	114699998	AI949687	6934	10q25.3	Hs.593995	246	blood vessel development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter anti-apoptosis cell cycle arrest beta-catenin binding transcription factor binding cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process specific transcriptional repressor activity protein kinase binding pancreas development positive regulation of insulin secretion regulation of hormone metabolic process glucose homeostasis fat cell differentiation regulation of transcription myoblast cell fate commitment Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
201643_x_at	-0.229	8.231	-2.438	2.750e-02	0.477	-3.526	KDM3B	lysine (K)-specific demethylase 3B	5	137716183	NM_016604	51780	5q31	Hs.714832	14	iron ion binding nucleus nucleolus zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
205280_at	0.601	3.878	2.438	2.750e-02	0.477	-3.526	GLRB	glycine receptor, beta	4	158216726	NM_000824	2743	4q31.3	Hs.32973	14	startle response ion channel activity extracellular ligand-gated ion channel activity protein binding membrane fraction plasma membrane integral to plasma membrane ion transport chloride transport neuropeptide signaling pathway synaptic transmission acrosome reaction nervous system development visual perception adult walking behavior glycine binding extracellular-glycine-gated chloride channel activity cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex regulation of membrane potential synapse postsynaptic membrane synaptic transmission, glycinergic righting reflex	Neuroactive ligand-receptor interaction
201854_s_at	-0.378	7.057	-2.438	2.751e-02	0.477	-3.526	ATMIN	ATM interactor	16	79626958	AI744148	23300	16q23.2	Hs.16349 Hs.589959	9	intracellular nucleus response to DNA damage stimulus zinc ion binding metal ion binding
1557736_at	-0.195	2.689	-2.438	2.751e-02	0.477	-3.526	NKTR	natural killer-tumor recognition sequence	3	42617150	AI880383	4820	3p23-p21	Hs.529509	9	peptidyl-prolyl cis-trans isomerase activity protein folding cyclosporin A binding membrane isomerase activity
227834_at	-0.485	9.571	-2.437	2.752e-02	0.477	-3.526	TXLNB	taxilin beta	6	-139602893	AL589605	167838	6q24.1	Hs.535820	12	cytoplasm
1568999_at	-0.191	4.615	-2.437	2.753e-02	0.477	-3.527	PSG4	pregnancy specific beta-1-glycoprotein 4	19	-48388693	BC035419	5672	19q13.2	Hs.654415	12	extracellular region defense response female pregnancy
230327_at	0.279	5.981	2.437	2.753e-02	0.477	-3.527	LOC730098	similar to chemokine (C-C motif) ligand 27	9		AI203673	730098	9p13.3	Hs.459590
203895_at	0.464	5.013	2.437	2.755e-02	0.477	-3.527	PLCB4	phospholipase C, beta 4	20	9024931	AL535113	5332	20p12	Hs.472101	17	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding intracellular signaling cascade lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
208015_at	0.309	5.324	2.437	2.756e-02	0.477	-3.528	SMAD1	SMAD family member 1	4	146622400, 146623406	NM_015583	4086	4q31	Hs.604588	118	MAPKKK cascade mesodermal cell fate commitment osteoblast fate commitment transcription factor activity RNA polymerase II transcription factor activity receptor signaling protein activity intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol inflammatory response signal transduction transforming growth factor beta receptor signaling pathway SMAD protein complex assembly gamete generation negative regulation of cell proliferation embryonic pattern specification positive regulation of gene expression integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity midbrain development hindbrain development primary microRNA processing homeostatic process identical protein binding positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter co-SMAD binding	TGF-beta signaling pathway
235780_at	0.325	3.224	2.436	2.758e-02	0.478	-3.528	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	1	84316332, 84316332, 84382539	BE622723	5567	1p36.1	Hs.487325	38	nucleotide binding magnesium ion binding protein serine/threonine kinase activity cAMP-dependent protein kinase activity ATP binding nucleus cytoplasm cAMP-dependent protein kinase complex protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger protein kinase cascade hormone-mediated signaling transferase activity	MAPK signaling pathway Calcium signaling pathway Chemokine signaling pathway Apoptosis Vascular smooth muscle contraction Wnt signaling pathway Hedgehog signaling pathway Gap junction Long-term potentiation Olfactory transduction Taste transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Vibrio cholerae infection
218638_s_at	0.309	6.922	2.436	2.760e-02	0.478	-3.529	SPON2	spondin 2, extracellular matrix protein	4	-1150720, -1150720	NM_012445	10417	4p16.3	Hs.302963	11	protein binding extracellular region proteinaceous extracellular matrix immune response cell adhesion axon guidance
221602_s_at	0.391	5.142	2.436	2.760e-02	0.478	-3.529	FAIM3	Fas apoptotic inhibitory molecule 3	1	-205143252, -205143252	AF057557	9214	1q32.1	Hs.58831 Hs.719320	10	nucleus cytoplasm plasma membrane focal adhesion anti-apoptosis immune response cellular defense response integral to membrane
203339_at	-0.458	8.822	-2.435	2.764e-02	0.478	-3.530	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	2	-172348160	AI887457	8604	2q24	Hs.470608	27	transporter activity L-glutamate transmembrane transporter activity calcium ion binding protein binding mitochondrion mitochondrial inner membrane transport L-aspartate transmembrane transporter activity aspartate transport L-glutamate transport membrane integral to membrane malate-aspartate shuttle response to calcium ion
242595_at	-0.173	3.058	-2.435	2.764e-02	0.478	-3.530	TSSK4	testis-specific serine kinase 4	14	23744801	AI218614	283629	14q12	Hs.314432	6	nucleotide binding magnesium ion binding magnesium ion binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding protein amino acid phosphorylation protein amino acid phosphorylation multicellular organismal development spermatogenesis transferase activity cell differentiation positive regulation of CREB transcription factor activity
208383_s_at	0.433	2.944	2.435	2.767e-02	0.478	-3.531	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	20	55569542	NM_002591	5105	20q13.31	Hs.1872	40	magnesium ion binding phosphoenolpyruvate carboxykinase (GTP) activity phosphoenolpyruvate carboxykinase (GTP) activity GTP binding nucleus nucleolus cytoplasm centrosome cytosol gluconeogenesis lipid metabolic process lyase activity purine nucleotide binding manganese ion binding carboxylic acid binding response to insulin stimulus glucose homeostasis glycerol biosynthetic process from pyruvate	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways PPAR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway
205039_s_at	0.247	6.700	2.435	2.767e-02	0.478	-3.531	IKZF1	IKAROS family zinc finger 1 (Ikaros)	7	50314923	NM_006060	10320	7p13-p11.1	Hs.435949 Hs.488251	52	DNA binding intracellular nucleus mesoderm development zinc ion binding regulation of transcription metal ion binding
1556854_at	0.420	2.878	2.434	2.770e-02	0.478	-3.532	LOC283501	hypothetical protein LOC283501	13		AA921835	283501	13q34	Hs.666761	1
228870_at	0.223	5.337	2.434	2.771e-02	0.478	-3.532	FAM84B	family with sequence similarity 84, member B	8	-127633868	BF732683	157638	8q24.21	Hs.124951	5	protein binding cytoplasm plasma membrane
218782_s_at	0.271	3.153	2.434	2.772e-02	0.478	-3.533	ATAD2	ATPase family, AAA domain containing 2	8	-124401271	NM_014109	29028	8q24.13	Hs.370834	9	nucleotide binding transcription factor activity ATP binding nucleus hydrolase activity nucleoside-triphosphatase activity ATPase activity, uncoupled regulation of transcription
208361_s_at	-0.222	6.380	-2.434	2.772e-02	0.478	-3.533	POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	8	22158563	NM_001722	661	8q21	Hs.148342	10	DNA binding DNA-directed RNA polymerase activity nucleus DNA-directed RNA polymerase III complex transcription transcription from RNA polymerase III promoter	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
207773_x_at	-0.275	3.682	-2.434	2.773e-02	0.478	-3.533	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	7	99263571	NM_022820	64816	7q21.1	Hs.306220 Hs.654391 Hs.695915	17	endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	gamma-Hexachlorocyclohexane degradation Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
204092_s_at	1.091	6.963	2.433	2.775e-02	0.478	-3.534	AURKA	aurora kinase A	20	-54377851	NM_003600	6790	20q13.2-q13.3	Hs.250822	196	nucleotide binding mitotic cell cycle protein serine/threonine kinase activity protein binding protein binding ATP binding nucleus centrosome spindle protein amino acid phosphorylation spindle organization mitosis transferase activity ubiquitin protein ligase binding regulation of protein stability phosphoinositide-mediated signaling
234542_at	0.241	2.802	2.433	2.776e-02	0.478	-3.534	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	11	119713155	AL080067	23365	11q23.3	Hs.24598	26	G-protein-coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm G-protein coupled receptor protein signaling pathway intracellular signaling cascade membrane regulation of Rho protein signal transduction	Vascular smooth muscle contraction Axon guidance Regulation of actin cytoskeleton
243722_at	-0.251	4.874	-2.433	2.778e-02	0.478	-3.535	PYDC1	PYD (pyrin domain) containing 1	16	-31134783	W73523	260434	16p11.2	Hs.58314	7	cysteine-type endopeptidase activity protein binding nucleus cytoplasm cytosol negative regulation of protein kinase activity proteolysis IkappaB kinase complex negative regulation of NF-kappaB transcription factor activity tumor necrosis factor-mediated signaling pathway innate immune response positive regulation of interleukin-1 beta secretion
236779_at	0.261	5.219	2.433	2.778e-02	0.478	-3.535	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	BG539414	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
204722_at	0.747	6.199	2.432	2.782e-02	0.479	-3.536	SCN3B	sodium channel, voltage-gated, type III, beta	11	-123005104	AW007335	55800	11q23.3	Hs.4865	19	voltage-gated ion channel activity voltage-gated sodium channel activity plasma membrane ion transport sodium ion transport integral to membrane sodium ion binding
213540_at	0.415	7.653	2.431	2.786e-02	0.479	-3.537	HSD17B8	hydroxysteroid (17-beta) dehydrogenase 8	6	33280396, 4552579, 4358588	AL031228	7923	6p21.3	Hs.415058	18	estradiol 17-beta-dehydrogenase activity retinoid-X receptor activity binding cellular_component membrane fraction mitochondrion mitochondrial envelope plasma membrane estrogen biosynthetic process androgen metabolic process oxidoreductase activity thyroid hormone receptor coactivator activity vitamin D receptor binding retinoic acid receptor binding thyroid hormone receptor binding protein heterodimerization activity testosterone 17-beta-dehydrogenase activity oxidation reduction	Androgen and estrogen metabolism Metabolic pathways
215705_at	0.249	5.818	2.431	2.787e-02	0.479	-3.537	PPP5C	protein phosphatase 5, catalytic subunit	19	51542133	BC000750	5536	19q13.3	Hs.654604	39	protein serine/threonine phosphatase activity signal transducer activity iron ion binding protein binding nucleus cytoplasm transcription protein amino acid dephosphorylation mitosis hydrolase activity manganese ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway
244699_at	0.275	4.775	2.431	2.788e-02	0.479	-3.538	AHI1	Abelson helper integration site 1	6	-135750615, -135646804	AV658469	54806	6q23.3	Hs.386684	30
224504_s_at	-0.211	6.374	-2.431	2.789e-02	0.479	-3.538	BUD13	BUD13 homolog (S. cerevisiae)	11	-116124097	BC006350	84811	11q23.3	Hs.437341	9
219098_at	0.340	6.941	2.430	2.793e-02	0.479	-3.539	MYBBP1A	MYB binding protein (P160) 1a	17	-4388939	NM_014520	10514	17p13.3	Hs.22824	24	DNA binding DNA-directed DNA polymerase activity nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent nucleocytoplasmic transport transcription factor binding NLS-dependent protein nuclear import complex
220277_at	0.275	4.774	2.430	2.793e-02	0.479	-3.539	CXXC4	CXXC finger 4	4	-105612791	NM_025212	80319	4q22-q24	Hs.12248	3	DNA binding cytoplasm zygotic determination of dorsal/ventral axis zinc ion binding cytoplasmic membrane-bounded vesicle PDZ domain binding negative regulation of Wnt receptor signaling pathway metal ion binding	Wnt signaling pathway
205762_s_at	0.291	4.496	2.430	2.793e-02	0.479	-3.539	DUS4L	dihydrouridine synthase 4-like (S. cerevisiae)	7	106991667	NM_007016	11062	7q22-q31	Hs.97627	5	tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity FAD binding oxidation reduction
208868_s_at	-0.325	6.745	-2.429	2.798e-02	0.480	-3.541	GABARAPL1	GABA(A) receptor-associated protein like 1	12	10256755	BF125756	23710	12p13.2	Hs.524250	18	protein binding intracellular cytoplasm autophagic vacuole endoplasmic reticulum Golgi apparatus microtubule membrane beta-tubulin binding GABA receptor binding	Regulation of autophagy
203479_s_at	-0.246	5.403	-2.428	2.802e-02	0.480	-3.542	OTUD4	OTU domain containing 4	4	-146299738, -146274251	T79216	54726	4q31.21	Hs.270851	13	molecular_function protein binding cellular_component biological_process
209203_s_at	-0.445	6.425	-2.428	2.804e-02	0.480	-3.543	BICD2	bicaudal D homolog 2 (Drosophila)	9	-94513465	BC002327	23299	9q22.31	Hs.436939	15	protein binding cytoplasm Golgi apparatus cytoskeleton transport microtubule-based movement
201030_x_at	0.736	10.837	2.428	2.804e-02	0.480	-3.543	LDHB	lactate dehydrogenase B	12	-21679542	NM_002300	3945	12p12.2-p12.1	Hs.446149	27	L-lactate dehydrogenase activity binding cytoplasm oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
203397_s_at	-0.196	2.696	-2.428	2.805e-02	0.480	-3.543	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)	2	-166312558	BF063271	2591	2q24-q31	Hs.170986	24	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding membrane fraction Golgi apparatus carbohydrate metabolic process membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
1554769_at	0.237	3.037	2.427	2.807e-02	0.480	-3.544	ZNF785	zinc finger protein 785	16	-30499494	BC040642	146540	16p11.2	Hs.513509	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1566957_at	-0.244	4.871	-2.427	2.807e-02	0.480	-3.544	OR7E104P	olfactory receptor, family 7, subfamily E, member 104 pseudogene	13		AL137719	81137	13q21.31	Hs.568153
222838_at	0.369	2.920	2.427	2.807e-02	0.480	-3.544	SLAMF7	SLAM family member 7	1	158975700	AL121985	57823	1q23.1-q24.1	Hs.517265	21	receptor activity cell adhesion membrane integral to membrane natural killer cell activation natural killer cell mediated cytotoxicity
1569111_at	-0.405	4.337	-2.426	2.814e-02	0.480	-3.546	SOX13	SRY (sex determining region Y)-box 13	1	202308868	BC040649	9580	1q32	Hs.201671	19	transcription factor activity nucleus anatomical structure morphogenesis sequence-specific DNA binding regulation of transcription
210011_s_at	-0.152	6.699	-2.426	2.814e-02	0.480	-3.546	EWSR1	Ewing sarcoma breakpoint region 1	22	27993997, 27993997	BC000527	2130	22q12.2	Hs.374477	90	nucleotide binding RNA binding calmodulin binding intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding
208066_s_at	-0.363	6.996	-2.426	2.815e-02	0.480	-3.546	GTF2B	general transcription factor IIB	1	-89090908	NM_001514	2959	1p22-p21	Hs.481852	98	translation initiation factor activity protein binding nucleus nucleoplasm transcription factor complex regulation of transcription, DNA-dependent transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter translational initiation zinc ion binding general RNA polymerase II transcription factor activity transcription regulator activity interspecies interaction between organisms metal ion binding	Basal transcription factors
217911_s_at	-0.248	10.389	-2.426	2.817e-02	0.480	-3.547	BAG3	BCL2-associated athanogene 3	10	121400871	NM_004281	9531	10q25.2-q26.2	Hs.523309	37	protein binding cellular_component cytosol protein folding anti-apoptosis
233375_at	0.704	6.225	2.425	2.819e-02	0.480	-3.547	EFCAB2	EF-hand calcium binding domain 2	1	243199793, 243199906, 243200253, 243200253	AK001393	84288	1q44	Hs.134857	5	calcium ion binding
202426_s_at	0.391	6.486	2.425	2.819e-02	0.480	-3.547	RXRA	retinoid X receptor, alpha	9	136358136	BE675800	6256	9q34.3	Hs.590886	190	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription coactivator activity retinoid-X receptor activity steroid binding protein binding nucleus regulation of transcription, DNA-dependent vitamin metabolic process cholesterol metabolic process zinc ion binding response to retinoic acid vitamin D receptor binding sequence-specific DNA binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter metal ion binding retinoic acid receptor signaling pathway ventricular cardiac muscle morphogenesis ventricular cardiac muscle cell differentiation cardiac muscle cell proliferation vitamin D response element binding	PPAR signaling pathway Adipocytokine signaling pathway Pathways in cancer Thyroid cancer Small cell lung cancer Non-small cell lung cancer
1553364_at	0.196	2.841	2.425	2.821e-02	0.480	-3.548	PNPLA1	patatin-like phospholipase domain containing 1	6	36318922, 36318957, 36346214	NM_173676	285848	6p21.31	Hs.407002	5	metabolic process lipid catabolic process hydrolase activity
220773_s_at	-0.286	5.619	-2.425	2.823e-02	0.480	-3.549	GPHN	gephyrin	14	66043877	NM_020806	10243	14q23.3	Hs.208765	29	nucleotide binding magnesium ion binding catalytic activity protein binding intracellular cytoplasm cytoskeleton plasma membrane Mo-molybdopterin cofactor biosynthetic process establishment of synaptic specificity at neuromuscular junction cell junction synapse postsynaptic membrane
226642_s_at	-0.290	7.567	-2.424	2.824e-02	0.480	-3.549	NUDCD2	NudC domain containing 2	5	-162813163	BF735901	134492	5q34	Hs.140443	7	intracellular
217364_x_at	-0.377	5.559	-2.424	2.824e-02	0.480	-3.549	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	AL031313	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
1557081_at	0.438	6.924	2.424	2.825e-02	0.480	-3.549	RBM25	RNA binding motif protein 25	14	72594973	AA580691	58517	14q24.3	Hs.531106	13	nucleotide binding nuclear mRNA splicing, via spliceosome nucleic acid binding mRNA binding cellular_component nucleus cytoplasm nuclear speck
213574_s_at	-0.340	8.607	-2.424	2.826e-02	0.480	-3.549	KPNB1	karyopherin (importin) beta 1	17	43082273	AA861608	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
214172_x_at	-0.266	5.901	-2.424	2.826e-02	0.480	-3.550	RYK	RYK receptor-like tyrosine kinase	3	-135358667	BG032035	6259	3q22	Hs.654562	13	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction axonogenesis transferase activity Wnt-protein binding Wnt receptor activity skeletal system morphogenesis
211985_s_at	-0.365	10.126	-2.424	2.827e-02	0.480	-3.550	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	AI653730	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
209770_at	0.344	5.674	2.424	2.828e-02	0.480	-3.550	BTN3A1	butyrophilin, subfamily 3, member A1	6	26510443	U90552	11119	6p22.1	Hs.191510 Hs.628564	10	lipid metabolic process membrane integral to membrane
219566_at	-0.351	7.622	-2.424	2.828e-02	0.480	-3.550	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	19	34848166	NM_024310	79156	19q12	Hs.466383	5	nucleus cytoplasm lysosome apoptosis induction of apoptosis zinc ion binding metal ion binding perinuclear region of cytoplasm
225075_at	-0.265	7.320	-2.423	2.829e-02	0.480	-3.551	PDRG1	p53 and DNA-damage regulated 1	20	-29996418	AL031658	81572	20q11.21	Hs.435755	6	cytoplasm protein folding prefoldin complex unfolded protein binding
209895_at	-0.759	5.951	-2.423	2.833e-02	0.481	-3.552	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	AF119855	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
203632_s_at	-0.249	7.897	-2.423	2.834e-02	0.481	-3.552	GPRC5B	G protein-coupled receptor, family C, group 5, member B	16	-19777793	NM_016235	51704	16p12	Hs.148685	8	receptor activity G-protein coupled receptor activity nucleus plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane cytoplasmic vesicle
214775_at	-0.205	4.810	-2.422	2.837e-02	0.481	-3.553	N4BP3	Nedd4 binding protein 3	5	177473161	AW139448	23138	5q35.3	Hs.101761	4	cytoplasm membrane cytoplasmic vesicle
204689_at	0.364	4.675	2.422	2.837e-02	0.481	-3.553	HHEX	hematopoietically expressed homeobox	10	94439660	NM_001529	3087	10q23.33	Hs.118651	86	liver development transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent mRNA export from nucleus cell cycle multicellular organismal development transcription factor binding eukaryotic initiation factor 4E binding organ morphogenesis anterior/posterior pattern formation positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter negative regulation of angiogenesis transcription repressor activity cell differentiation positive regulation of Wnt receptor signaling pathway thyroid gland development forebrain development negative regulation of vascular endothelial growth factor receptor signaling pathway embryonic heart tube development regulation of cell proliferation sequence-specific DNA binding	Maturity onset diabetes of the young
212870_at	-0.517	9.163	-2.422	2.838e-02	0.481	-3.553	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	AI628605	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
200930_s_at	-0.176	3.383	-2.421	2.843e-02	0.481	-3.555	VCL	vinculin	10	75427877	AA156675	7414	10q22.2	Hs.643896	78	actin binding structural molecule activity cytoplasm plasma membrane cell-cell junction adherens junction focal adhesion cell motion cell adhesion actin cytoskeleton oxidoreductase activity lamellipodium assembly cell-substrate junction negative regulation of cell migration costamere protein complex apical junction assembly alpha-catenin binding	Focal adhesion Adherens junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
202780_at	1.039	7.181	2.421	2.843e-02	0.481	-3.555	OXCT1	3-oxoacid CoA transferase 1	5	-41765923	NM_000436	5019	5p13.1	Hs.278277	15	mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix metabolic process 3-oxoacid CoA-transferase activity 3-oxoacid CoA-transferase activity transferase activity protein homodimerization activity ketone body catabolic process	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism
223875_s_at	-0.336	4.416	-2.421	2.844e-02	0.481	-3.555	EPC1	enhancer of polycomb homolog 1 (Drosophila)	10	-32597864	AF277374	80314	10p11	Hs.167805 Hs.510635 Hs.621281	16	negative regulation of transcription from RNA polymerase II promoter histone acetyltransferase activity nucleus nucleoplasm transcription activator activity transcription repressor activity chromatin modification nuclear membrane Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation regulation of transcription negative regulation of gene expression, epigenetic positive regulation of transcription from RNA polymerase II promoter
219207_at	-0.245	5.522	-2.421	2.845e-02	0.481	-3.555	EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	15	-72709952	NM_025083	80153	15q24.1	Hs.682454 Hs.96852	16	cytoplasmic mRNA processing body protein binding cytoplasm	RNA degradation
238303_at	0.272	4.128	2.421	2.845e-02	0.481	-3.555	STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	3	31549494	AW070371	201595	3p23	Hs.475812	9	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum protein amino acid glycosylation membrane integral to membrane transferase activity	N-Glycan biosynthesis Metabolic pathways
225063_at	0.283	7.547	2.420	2.846e-02	0.481	-3.556	UBL7	ubiquitin-like 7 (bone marrow stromal cell-derived)	15	-72525370, -72525370	BF568780	84993	15q24.1	Hs.334713	7	protein binding modification-dependent protein catabolic process
208463_at	0.280	4.592	2.420	2.848e-02	0.481	-3.556	GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	4	-46615673	NM_000809	2557	4p12	Hs.248112	17	GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport chloride transport gamma-aminobutyric acid signaling pathway benzodiazepine receptor activity cell junction chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
224452_s_at	-0.538	9.919	-2.420	2.850e-02	0.481	-3.557	C7orf70	chromosome 7 open reading frame 70	7	-6335564	BC006110	84792	7p22.1	Hs.696146	4	nucleus
210707_x_at	0.323	6.523	2.420	2.851e-02	0.481	-3.557	PMS2L11	postmeiotic segregation increased 2-like 11 pseudogene	7	76448074	U38980	441263	7q11.23	Hs.675888	5
823_at	-0.402	6.266	-2.419	2.852e-02	0.481	-3.558	CX3CL1	chemokine (C-X3-C motif) ligand 1	16	55963914	U84487	6376	16q13	Hs.531668	100	extracellular region extracellular space plasma membrane chemotaxis defense response immune response cell adhesion chemokine activity cell surface integral to membrane cytokine-mediated signaling pathway leukocyte chemotaxis positive regulation of inflammatory response leukocyte adhesive activation positive regulation of calcium-independent cell-cell adhesion	Cytokine-cytokine receptor interaction Chemokine signaling pathway
1569617_at	0.225	4.959	2.419	2.853e-02	0.481	-3.558	OSBP2	oxysterol binding protein 2	22	29420792	BC018025	23762	22q12.2	Hs.517546	11	lipid transport steroid metabolic process membrane
229034_at	-0.453	4.997	-2.419	2.854e-02	0.481	-3.558	SOBP	sine oculis binding protein homolog (Drosophila)	6	107918009	BF511724	55084	6q21	Hs.445244	4	zinc ion binding metal ion binding
1559927_a_at	-0.174	5.299	-2.419	2.856e-02	0.481	-3.559	LOC728353	hypothetical protein LOC728353	14		BC031683	728353	14q11.2	Hs.621210
1555942_a_at	-0.199	3.760	-2.418	2.857e-02	0.481	-3.559	LOC642587	NPC-A-5	1	207668790	AK091113	642587	1q32.2	Hs.510543	2
213140_s_at	-0.227	7.115	-2.418	2.861e-02	0.481	-3.560	SS18L1	synovial sarcoma translocation gene on chromosome 18-like 1	20	60152216	AB014593	26039	20q13.3	Hs.154429	10	condensed nuclear chromosome, centromeric region protein binding dendrite development
218031_s_at	-0.399	8.265	-2.418	2.861e-02	0.481	-3.560	FOXN3	forkhead box N3	14	-88692268, -88692268	NM_018589	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
226028_at	0.294	7.036	2.418	2.861e-02	0.481	-3.560	ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	11	-124259324	AA156022	54538	11q24.2	Hs.524121	19	angiogenesis receptor activity multicellular organismal development integral to membrane cell differentiation regulation of cell migration
232235_at	0.468	2.882	2.417	2.863e-02	0.481	-3.561	DSEL	dermatan sulfate epimerase-like	18	-63324798	AK021539	92126	18q22.1	Hs.124673	6	membrane integral to membrane
200959_at	0.275	8.375	2.417	2.865e-02	0.481	-3.562	FUS	fusion (involved in t(12;16) in malignant liposarcoma)	16	31098953	NM_004960	2521	16p11.2	Hs.513522	55	nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding intracellular nucleus nucleolus cell death zinc ion binding metal ion binding
1554745_at	-0.169	4.380	-2.417	2.865e-02	0.481	-3.562	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1	9	128716873	BC032372	9649	9q33.3	Hs.648175	4	guanyl-nucleotide exchange factor activity cellular_component intracellular cytoplasm plasma membrane small GTPase mediated signal transduction
213897_s_at	0.325	8.690	2.417	2.866e-02	0.481	-3.562	MRPL23	mitochondrial ribosomal protein L23	11	1925077	AI832239	6150	11p15.5-p15.4	Hs.3254	11	nucleotide binding RNA binding structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation
202555_s_at	0.539	6.203	2.416	2.868e-02	0.482	-3.562	MYLK	myosin light chain kinase	3	-124813832, -124813832	NM_005965	4638	3q21	Hs.477375	56	nucleotide binding magnesium ion binding actin binding myosin light chain kinase activity calcium ion binding calmodulin binding ATP binding protein amino acid phosphorylation transferase activity	Calcium signaling pathway Vascular smooth muscle contraction Focal adhesion Regulation of actin cytoskeleton
230864_at	-0.271	4.637	-2.415	2.876e-02	0.482	-3.565	MGC42105	serine/threonine-protein kinase NIM1	5	43228083	BF222940	167359	5p12	Hs.25845	4	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
213151_s_at	-0.264	9.516	-2.414	2.880e-02	0.482	-3.566	SEPT7	septin 7	7	35807151	AU157515	989	7p14.3-p14.1	Hs.191346 Hs.642540	23	nucleotide binding condensed chromosome kinetochore cytokinesis stress fiber structural molecule activity protein binding GTP binding nucleus cytoplasm spindle cell cycle mitosis septin complex protein heterooligomerization
1569796_s_at	0.303	4.522	2.414	2.882e-02	0.482	-3.567	ATRNL1	attractin-like 1	10	116843113	BC035157	26033	10q26	Hs.501127	3	binding sugar binding membrane integral to membrane
217010_s_at	-0.260	2.687	-2.414	2.882e-02	0.482	-3.567	CDC25C	cell division cycle 25 homolog C (S. pombe)	5	-137648857	AF277724	995	5q31	Hs.656	108	regulation of cyclin-dependent protein kinase activity protein tyrosine phosphatase activity protein binding cellular_component intracellular nucleus nucleoplasm cytoplasm cytosol DNA replication protein amino acid dephosphorylation cell cycle regulation of mitosis traversing start control point of mitotic cell cycle cell proliferation hydrolase activity interspecies interaction between organisms WW domain binding cell division	Cell cycle
207826_s_at	-0.498	7.107	-2.414	2.883e-02	0.482	-3.567	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	1	-23756995	NM_002167	3399	1p36.13-p36.12	Hs.76884	41	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus nucleus regulation of DNA replication multicellular organismal development heart development transcription factor binding response to wounding negative regulation of transcription protein domain specific binding neuron differentiation epithelial cell differentiation positive regulation of apoptosis negative regulation of transcription factor activity	TGF-beta signaling pathway
1555167_s_at	-0.496	6.552	-2.414	2.883e-02	0.482	-3.567	NAMPT	nicotinamide phosphoribosyltransferase	7	-105675967	BC020691	10135	7q22.3	Hs.489615	98	cytokine activity cytoplasm cytosol signal transduction cell-cell signaling positive regulation of cell proliferation NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity	Nicotinate and nicotinamide metabolism
225183_at	-0.270	8.512	-2.414	2.884e-02	0.482	-3.567	C16orf72	chromosome 16 open reading frame 72	16	9093037	BG495327	29035	16p13.2	Hs.221497	3
230298_at	0.343	6.354	2.413	2.885e-02	0.482	-3.568	MBLAC2	metallo-beta-lactamase domain containing 2	5	-89789775	AI692906	153364	5q14.3	Hs.64004	2	zinc ion binding hydrolase activity metal ion binding
1554126_at	-0.333	8.070	-2.413	2.887e-02	0.483	-3.568	MSRB3	methionine sulfoxide reductase B3	12	63958754	BC040053	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
218918_at	0.247	5.636	2.412	2.894e-02	0.483	-3.570	MAN1C1	mannosidase, alpha, class 1C, member 1	1	25816545	NM_020379	57134	1p35	Hs.197043	26	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding Golgi apparatus protein amino acid N-linked glycosylation metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds integral to Golgi membrane	N-Glycan biosynthesis Metabolic pathways
220123_at	0.549	3.457	2.412	2.895e-02	0.483	-3.571	SLC35F5	solute carrier family 35, member F5	2	-114188402	NM_025181	80255	2q14.1	Hs.632527	2	transport membrane integral to membrane
216265_x_at	0.328	12.421	2.411	2.896e-02	0.483	-3.571	MYH7	myosin, heavy chain 7, cardiac muscle, beta	14	-22951786	AI292276	4625	14q12	Hs.678918	129	microfilament motor activity nucleotide binding regulation of heart rate actin binding calmodulin binding ATP binding nucleus nucleolus cytoplasm striated muscle thick filament focal adhesion ATP catabolic process striated muscle contraction adult heart development structural constituent of muscle myosin complex ATPase activity muscle filament sliding actin-dependent ATPase activity ventricular cardiac muscle morphogenesis	Cardiac muscle contraction Tight junction Hypertrophic cardiomyopathy (HCM)
201652_at	-0.200	9.954	-2.411	2.897e-02	0.483	-3.571	COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	8	-68117868	NM_006837	10987	8q13.1	Hs.491912	79	protein deneddylation transcription coactivator activity translation initiation factor activity protein binding nucleus nucleolus cytoplasm eukaryotic translation initiation factor 3 complex transcription from RNA polymerase II promoter translation signalosome peptidase activity metallopeptidase activity metal ion binding regulation of cell cycle
202397_at	0.224	9.555	2.411	2.897e-02	0.483	-3.571	NUTF2	nuclear transport factor 2	16	66438319	NM_005796	10204	16q22.1	Hs.719219	19	transporter activity protein binding intracellular nuclear pore cytoplasm cytosol protein import into nucleus protein transporter activity protein transport
227693_at	-0.373	6.115	-2.411	2.898e-02	0.484	-3.572	WDR20	WD repeat domain 20	14	101675964, 101675964, 101675964	AI092930	91833	14q32.31	Hs.36859	7
225342_at	0.543	5.487	2.411	2.900e-02	0.484	-3.572	AK3L1	adenylate kinase 3-like 1	1	65385819, 65386100, 65386473	AK026966	205	1p31.3	Hs.10862 Hs.592601	10	nucleotide binding adenylate kinase activity ATP binding GTP binding mitochondrion mitochondrial matrix nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity	Purine metabolism Metabolic pathways
204732_s_at	-0.399	6.011	-2.411	2.901e-02	0.484	-3.572	TRIM23	tripartite motif-containing 23	5	-64921262	AI021991	373	5q12.3	Hs.792	14	Golgi membrane nucleotide binding GTPase activity ubiquitin-protein ligase activity protein binding GTP binding intracellular nucleus cytoplasm lysosomal membrane Golgi apparatus small GTPase mediated signal transduction enzyme activator activity zinc ion binding membrane protein ubiquitination GDP binding metal ion binding
228708_at	0.216	4.659	2.410	2.903e-02	0.484	-3.573	RAB27B	RAB27B, member RAS oncogene family	18	50646837	BF438386	5874	18q21.2	Hs.25318	14	nucleotide binding GTPase activity protein binding GTP binding Golgi apparatus small GTPase mediated signal transduction protein transport membrane
229955_at	0.302	4.945	2.410	2.904e-02	0.484	-3.573	FBXO3	F-box protein 3	11	-33724866, -33719065	AW772096	26273	11p13	Hs.406787	8	ubiquitin-protein ligase activity proteolysis modification-dependent protein catabolic process
202577_s_at	-0.315	6.353	-2.409	2.909e-02	0.484	-3.575	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A	16	68938324	BC005162	55308	16q22.1	Hs.656037	5	nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport
221530_s_at	-0.590	9.452	-2.409	2.910e-02	0.484	-3.575	BHLHE41	basic helix-loop-helix family, member e41	12	-26164227	BE857425	79365	12p11.23-p12.1	Hs.177841	15	transcription factor activity nucleus regulation of transcription, DNA-dependent cell proliferation organ morphogenesis cell differentiation	Circadian rhythm - mammal
218328_at	0.221	6.725	2.409	2.911e-02	0.484	-3.575	COQ4	coenzyme Q4 homolog (S. cerevisiae)	9	130124611	NM_016035	51117	9q34.11	Hs.98541	9	mitochondrion ubiquinone biosynthetic process
230076_at	0.218	3.351	2.409	2.912e-02	0.485	-3.576	PITPNM3	PITPNM family member 3	17	-6295306	BF063164	83394	17p13	Hs.183983	5	calcium ion binding intracellular transport visual perception lipid binding phosphatidylinositol transporter activity membrane integral to membrane phosphoinositide metabolic process receptor tyrosine kinase binding response to stimulus
225835_at	-0.925	7.477	-2.408	2.915e-02	0.485	-3.577	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2	5	127447381	AK025062	6558	5q23.3	Hs.162585 Hs.712970	29	transporter activity membrane fraction integral to plasma membrane ion transport potassium ion transport sodium ion transport sodium:potassium:chloride symporter activity symporter activity membrane transepithelial chloride transport potassium ion binding sodium ion binding ammonia transporter activity transepithelial ammonium transport	Vibrio cholerae infection
206666_at	0.279	4.091	2.408	2.918e-02	0.485	-3.578	GZMK	granzyme K (granzyme 3; tryptase II)	5	54355863	NM_002104	3003	5q11-q12	Hs.277937	15	serine-type endopeptidase activity extracellular region proteolysis peptidase activity
216981_x_at	-0.590	6.108	-2.408	2.919e-02	0.485	-3.578	SPN	sialophorin	16	29581800, 29582080	X60502	6693	16p11.2	Hs.632188	44	response to protozoan negative regulation of type IV hypersensitivity uropod transmembrane receptor activity protein binding basement membrane extracellular space integral to plasma membrane chemotaxis cellular defense response negative regulation of cell adhesion establishment or maintenance of cell polarity cell surface receptor linked signal transduction bacterial binding induction of apoptosis by extracellular signals external side of plasma membrane membrane T cell costimulation positive regulation of T cell proliferation negative regulation of T cell proliferation positive regulation of tumor necrosis factor biosynthetic process defense response to bacterium negative thymic T cell selection regulation of defense response to virus regulation of immune response	Cell adhesion molecules (CAMs)
1561342_at	-0.274	4.131	-2.408	2.919e-02	0.485	-3.578	LOC150005	hypothetical protein LOC150005	21		AI677840	150005	21q21.1	Hs.606124	1
211380_s_at	-0.412	5.933	-2.407	2.920e-02	0.485	-3.578	PRKG1	protein kinase, cGMP-dependent, type I	10	52420950, 52504239	D45864	5592	10q11.2	Hs.654556	76	nucleotide binding neuron migration protein serine/threonine kinase activity cGMP-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation signal transduction dendrite development transferase activity actin cytoskeleton organization cGMP binding forebrain development	Vascular smooth muscle contraction Gap junction Long-term depression Olfactory transduction
204247_s_at	0.260	6.258	2.406	2.926e-02	0.486	-3.580	CDK5	cyclin-dependent kinase 5	7	-150381831	NM_004935	1020	7q36	Hs.647078	132	nucleotide binding neuron migration synaptic transmission, dopaminergic p53 binding cyclin-dependent protein kinase activity ErbB-2 class receptor binding ATP binding nucleus cytoplasm cytosol protein amino acid phosphorylation intracellular protein transport cell-matrix adhesion axonogenesis skeletal muscle tissue development motor axon guidance cell proliferation associative learning visual learning embryonic development Schwann cell development membrane transferase activity sensory perception of pain cerebellar cortex development cerebellar cortex formation hippocampus development layer formation in the cerebral cortex central nervous system neuron development cerebral cortex development corpus callosum development lamellipodium filopodium neuron differentiation regulation of cell migration axon dendrite growth cone acetylcholine receptor activator activity neuron projection development negative regulation of protein ubiquitination neuromuscular junction negative regulation of synaptic plasticity receptor catabolic process serine phosphorylation of STAT3 protein synaptic transmission, glutamatergic cell soma receptor clustering ErbB-3 class receptor binding positive regulation of neuron apoptosis negative regulation of cell cycle positive regulation of protein kinase activity positive regulation of calcium ion-dependent exocytosis negative regulation of protein export from nucleus behavioral response to cocaine dendrite morphogenesis tau-protein kinase activity cell division regulation of excitatory postsynaptic membrane potential	Axon guidance Alzheimer's disease
204219_s_at	-0.234	10.248	-2.406	2.927e-02	0.486	-3.580	PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	14	89792646	NM_002802	5700	14q32.11	Hs.356654	51	nucleotide binding proteasome complex protein binding ATP binding nucleus nucleolus cytoplasm cytosol hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
236109_at	0.398	5.899	2.406	2.930e-02	0.486	-3.581	RPUSD4	RNA pseudouridylate synthase domain containing 4	11	-125577199	BE674055	84881	11q24.2	Hs.150458	5	pseudouridine synthesis RNA binding pseudouridine synthase activity
234098_at	0.278	5.202	2.405	2.932e-02	0.486	-3.582	SOBP	sine oculis binding protein homolog (Drosophila)	6	107918009	AK021973	55084	6q21	Hs.445244	4	zinc ion binding metal ion binding
209015_s_at	-0.299	10.020	-2.405	2.936e-02	0.486	-3.583	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	7	156822470, 156822471	BC002446	10049	7q36.3	Hs.593923 Hs.719116	25	ATPase activator activity DNA binding nucleus cytoplasm protein folding response to unfolded protein transcription repressor activity heat shock protein binding negative regulation of caspase activity intermediate filament organization negative regulation of transcription, DNA-dependent perinuclear region of cytoplasm chaperone binding
1569374_at	0.260	3.751	2.405	2.936e-02	0.486	-3.583	C3orf62	chromosome 3 open reading frame 62	3	-49281033	BC032616	375341	3p21.31	Hs.403828	3
225206_s_at	-0.213	7.299	-2.404	2.937e-02	0.486	-3.583	MTRF1L	mitochondrial translational release factor 1-like	6	-153350092	AI479199	54516	6q25-q26	Hs.225836 Hs.304818	9	cytoplasm mitochondrion translational termination translation release factor activity, codon specific
225346_at	0.369	6.759	2.404	2.937e-02	0.486	-3.583	MTERFD3	MTERF domain containing 3	12	-105895198	NM_025198	80298	12q24.1	Hs.5009	6	mitochondrion transcription termination regulation of transcription
217465_at	-0.344	3.667	-2.404	2.939e-02	0.486	-3.584	NCKAP1	NCK-associated protein 1	2	-183497849	AK001291	10787	2q32	Hs.603732	20	protein binding plasma membrane apoptosis central nervous system development integral to membrane cell projection	Regulation of actin cytoskeleton
201388_at	-0.252	7.184	-2.404	2.939e-02	0.486	-3.584	PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	17	35390585	NM_002809	5709	17q21.1	Hs.12970	34	proteasome complex protein binding cytosol enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
218736_s_at	-0.383	8.679	-2.404	2.942e-02	0.486	-3.585	PALMD	palmdelphin	1	99884018	NM_017734	54873	1p22-p21	Hs.483993	7	cytoplasm regulation of cell shape membrane
227325_at	-0.244	6.610	-2.403	2.943e-02	0.486	-3.585	LOC255783	hypothetical protein LOC255783	19	52469981	AW172584	255783	19q13.32	Hs.128690	1
211276_at	0.226	3.057	2.403	2.945e-02	0.486	-3.586	TCEAL2	transcription elongation factor A (SII)-like 2	X	101267315	AF063606	140597	Xq22.1-q22.3	Hs.401835	6	nucleus regulation of transcription
209384_at	0.187	8.240	2.403	2.946e-02	0.486	-3.586	PROSC	proline synthetase co-transcribed homolog (bacterial)	8	37739258	AA176833	11212	8p11.2	Hs.304792 Hs.608177	8	intracellular cytoplasm
232964_at	-0.278	6.153	-2.403	2.947e-02	0.486	-3.586	SPDYE1	speedy homolog E1 (Xenopus laevis)	7	44007013	AL137266	285955	7p13	Hs.645483	2
221295_at	0.207	4.973	2.401	2.954e-02	0.487	-3.588	CIDEA	cell death-inducing DFFA-like effector a	18	12244317, 12244627	NM_001279	1149	18 18p11.21	Hs.249129	15	temperature homeostasis protein binding intracellular nucleus cytoplasm mitochondrion mitochondrial envelope lipid particle DNA fragmentation involved in apoptosis lipid metabolic process cell death DNA damage response, signal transduction resulting in induction of apoptosis positive regulation of sequestering of triglyceride lipid storage negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of tumor necrosis factor production protein homodimerization activity negative regulation of apoptosis negative regulation of cytokine secretion negative regulation of lipid catabolic process
243617_at	0.257	6.123	2.401	2.955e-02	0.487	-3.589	ZNF827	zinc finger protein 827	4	-146901337	BF678830	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
45526_g_at	-0.375	8.498	-2.401	2.955e-02	0.487	-3.589	NAT15	N-acetyltransferase 15 (GCN5-related, putative)	16	3433668, 3447992	AI246641	79903	16p13.3	Hs.513296	6	N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
1558675_s_at	-0.330	6.888	-2.401	2.958e-02	0.487	-3.589	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	AV724508	9147	14q22	Hs.655964	8	nucleus cytoplasm
235809_at	-0.275	3.853	-2.401	2.958e-02	0.487	-3.589	LIN54	lin-54 homolog (C. elegans)	4	-84064780, -84064780	BF678497	132660	4q21.22	Hs.96952	2	nucleus chromosome regulation of transcription
223315_at	0.553	5.790	2.401	2.959e-02	0.487	-3.590	NTN4	netrin 4	12	-94575713	AF278532	59277	12q22 12q22-q23	Hs.201034	9	protein binding extracellular region basement membrane neuron remodeling	Axon guidance
214057_at	-0.413	4.910	-2.401	2.959e-02	0.487	-3.590	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	1	-148813658	H71805	4170	1q21	Hs.719112	154	cell fate determination protein binding nucleus nucleoplasm cytoplasm mitochondrion mitochondrial outer membrane anti-apoptosis multicellular organismal development protein channel activity membrane integral to membrane cellular homeostasis cell differentiation response to cytokine stimulus regulation of apoptosis protein heterodimerization activity
226360_at	0.424	5.470	2.400	2.960e-02	0.487	-3.590	ZNRF3	zinc and ring finger 3	22	27609889	AK022809	84133	22q12.1	Hs.655242	8	protein binding zinc ion binding membrane integral to membrane metal ion binding
218541_s_at	-0.684	7.090	-2.400	2.962e-02	0.487	-3.591	C8orf4	chromosome 8 open reading frame 4	8	40130145	NM_020130	56892	8p11.2	Hs.591849	13	apoptosis
1559576_at	0.246	4.110	2.400	2.963e-02	0.487	-3.591	WDR78	WD repeat domain 78	1	-67075873, -67051159	BI088045	79819	1p31.3	Hs.49421	4
242663_at	0.232	4.550	2.399	2.970e-02	0.487	-3.593	LOC148189	hypothetical LOC148189	19	-32973241	AA115127	148189	19q11	Hs.565253	2
225866_at	-0.285	8.184	-2.398	2.972e-02	0.487	-3.593	BXDC1	brix domain containing 1	6	111409983	AA976536	84154	6q21	Hs.372265	8	protein binding nucleus nucleolus
226778_at	-0.200	4.347	-2.398	2.972e-02	0.487	-3.593	C8orf42	chromosome 8 open reading frame 42	8	-431645	AI632224	157695	8p23.3	Hs.289293	1
240140_s_at	-0.213	4.271	-2.398	2.974e-02	0.487	-3.594	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	3	-66511910	AW293282	26018	3p14	Hs.518055	18	protein binding membrane integral to membrane
217852_s_at	-0.423	8.728	-2.398	2.975e-02	0.487	-3.594	ARL8B	ADP-ribosylation factor-like 8B	3	5138929	NM_018184	55207	3p26.1	Hs.250009 Hs.719100	10	nucleotide binding GTPase activity GTP binding intracellular cytoplasm lysosomal membrane endosome chromosome segregation small GTPase mediated signal transduction membrane GDP binding midbody late endosome membrane alpha-tubulin binding beta-tubulin binding spindle midzone
1555326_a_at	-0.448	4.830	-2.398	2.976e-02	0.487	-3.595	ADAM9	ADAM metallopeptidase domain 9 (meltrin gamma)	8	38973661, 38973661	AF495383	8754	8p11.22	Hs.591852	36	activation of MAPKK activity metalloendopeptidase activity protein kinase C binding integrin binding integrin binding integrin binding collagen binding extracellular region extracellular space cytoplasm plasma membrane proteolysis response to oxidative stress cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway peptidase activity zinc ion binding cell surface response to manganese ion integral to membrane SH3 domain binding SH3 domain binding keratinocyte differentiation intrinsic to external side of plasma membrane positive regulation of cell adhesion mediated by integrin cell-cell adhesion mediated by integrin positive regulation of macrophage fusion response to tumor necrosis factor monocyte activation response to hydrogen peroxide laminin binding metal ion binding positive regulation of protein secretion positive regulation of membrane protein ectodomain proteolysis PMA-inducible membrane protein ectodomain proteolysis response to glucocorticoid stimulus positive regulation of keratinocyte migration response to calcium ion
202081_at	-0.534	7.070	-2.398	2.976e-02	0.487	-3.595	IER2	immediate early response 2	19	13122281	NM_004907	9592	19p13.2	Hs.501629	3	cytoplasm
1559369_at	-0.340	3.168	-2.398	2.976e-02	0.487	-3.595	C5orf44	chromosome 5 open reading frame 44	5	64956313, 64956313	BI668018	80006	5q12.3	Hs.591760	5
225262_at	-0.376	6.462	-2.398	2.977e-02	0.487	-3.595	FOSL2	FOS-like antigen 2	2	28469282	AI670862	2355	2p23.3	Hs.220971 Hs.596972	20	transcription factor activity nucleus nucleolus regulation of transcription from RNA polymerase II promoter cell death sequence-specific DNA binding protein dimerization activity positive regulation of fibroblast proliferation
209160_at	1.366	8.487	2.397	2.977e-02	0.487	-3.595	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	10	5126567	AB018580	8644	10p15-p14	Hs.78183	68	aldo-keto reductase activity intracellular cytoplasm prostaglandin metabolic process oxidoreductase activity prostaglandin-F synthase activity 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity testosterone 17-beta-dehydrogenase (NADP+) activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity indanol dehydrogenase activity testosterone 17-beta-dehydrogenase activity oxidation reduction	Arachidonic acid metabolism Metabolism of xenobiotics by cytochrome P450
203226_s_at	-0.271	7.757	-2.397	2.977e-02	0.487	-3.595	TSPAN31	tetraspanin 31	12	56425050	AL514076	6302	12q13.3	Hs.632708	12	membrane fraction integral to plasma membrane positive regulation of cell proliferation membrane
209154_at	0.554	8.433	2.397	2.980e-02	0.487	-3.596	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	17	-3512937	AF234997	30851	17p13	Hs.12956	14	nucleus cytoplasm Rho protein signal transduction beta-catenin binding negative regulation of cell proliferation negative regulation of Wnt receptor signaling pathway transcription regulator activity
223124_s_at	-0.312	8.444	-2.397	2.982e-02	0.488	-3.596	C1orf128	chromosome 1 open reading frame 128	1	23977462	AF271784	57095	1p36.11	Hs.31819	4
218175_at	0.259	8.233	2.396	2.985e-02	0.488	-3.597	CCDC92	coiled-coil domain containing 92	12	-122986907	NM_025140	80212	12q24.31	Hs.114111	5
206174_s_at	-0.349	7.891	-2.396	2.986e-02	0.488	-3.597	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	NM_002721	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
209027_s_at	-0.359	5.959	-2.395	2.990e-02	0.488	-3.599	ABI1	abl-interactor 1	10	-27075530	BF673013	10006	10p11.2	Hs.508148	39	intracellular soluble fraction nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal protein binding negative regulation of cell proliferation peptidyl-tyrosine phosphorylation synaptosome lamellipodium cell junction filopodium growth cone synapse
217315_s_at	-0.221	5.222	-2.395	2.992e-02	0.488	-3.599	KLK13	kallikrein-related peptidase 13	19	-56251274	AL050220	26085	19q13.3-q13.4	Hs.165296	18	serine-type endopeptidase activity protein binding extracellular region cytoplasm proteolysis peptidase activity
235259_at	-0.239	3.065	-2.395	2.992e-02	0.488	-3.599	PACRGL	PARK2 co-regulated-like	4	20311133	AA398590	133015	4p15.31	Hs.479298	5	binding
203389_at	0.204	5.823	2.395	2.993e-02	0.488	-3.600	KIF3C	kinesin family member 3C	2	-26002958	AF035621	3797	2p23	Hs.21611	9	nucleotide binding microtubule motor activity ATP binding kinesin complex microtubule microtubule-based movement
212530_at	-0.329	9.438	-2.395	2.994e-02	0.488	-3.600	NEK7	NIMA (never in mitosis gene a)-related kinase 7	1	196392730	AL080111	140609	1q31.3	Hs.24119	7	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
202512_s_at	-0.358	6.611	-2.395	2.994e-02	0.488	-3.600	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	6	-106739044	NM_004849	9474	6q21	Hs.486063	30	autophagic vacuole formation protein binding cytoplasm autophagic vacuole autophagy apoptosis pre-autophagosomal structure membrane post-translational protein modification	Regulation of autophagy RIG-I-like receptor signaling pathway
200978_at	0.248	12.281	2.394	2.995e-02	0.488	-3.600	MDH1	malate dehydrogenase 1, NAD (soluble)	2	63669625	NM_005917	4190	2p13.3	Hs.526521	18	malic enzyme activity binding soluble fraction cytoplasm cytosol cytosol glycolysis tricarboxylic acid cycle oxaloacetate metabolic process malate metabolic process oxidoreductase activity NAD metabolic process L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
202593_s_at	-0.659	7.613	-2.394	2.996e-02	0.488	-3.601	GDE1	glycerophosphodiester phosphodiesterase 1	16	-19420515	NM_016641	51573	16p12-p11.2	Hs.512607	8	magnesium ion binding cytoplasm glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity glycerophosphoinositol glycerophosphodiesterase activity	Glycerophospholipid metabolism
218653_at	0.410	6.541	2.394	2.997e-02	0.488	-3.601	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	13	40261546	NM_014252	10166	13q14	Hs.646645 Hs.655240	17	urea cycle L-ornithine transmembrane transporter activity mitochondrial ornithine transport transporter activity binding mitochondrion mitochondrial inner membrane cellular amino acid metabolic process transport membrane integral to membrane
210825_s_at	0.266	10.757	2.394	2.997e-02	0.488	-3.601	PEBP1	phosphatidylethanolamine binding protein 1	12	117058252	AF130103	5037	12q24.23	Hs.433863 Hs.718605	55	nucleotide binding serine-type endopeptidase inhibitor activity protein binding ATP binding cytoplasm lipid binding phosphatidylethanolamine binding peptidase inhibitor activity
213034_at	0.267	7.272	2.394	2.998e-02	0.488	-3.601	QSK	serine/threonine-protein kinase QSK	11	-116219327	AB023216	23387	11q23.3	Hs.167451	14	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
1555197_a_at	-0.193	4.342	-2.394	2.998e-02	0.488	-3.601	C21orf58	chromosome 21 open reading frame 58	21	-46545474	AY039243	54058	21q22.3	Hs.236572	5
205345_at	-0.512	5.725	-2.394	3.000e-02	0.488	-3.602	BARD1	BRCA1 associated RING domain 1	2	-215301519	NM_000465	580	2q34-q35	Hs.591642	100	ubiquitin ligase complex tissue homeostasis RNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleus cytoplasm DNA repair response to DNA damage stimulus cell cycle arrest zinc ion binding protein ubiquitination ligase activity kinase binding modification-dependent protein catabolic process BRCA1-BARD1 complex negative regulation of mRNA 3'-end processing regulation of phosphorylation protein homodimerization activity positive regulation of apoptosis negative regulation of apoptosis positive regulation of protein catabolic process negative regulation of protein export from nucleus metal ion binding protein heterodimerization activity BRCA1-A complex
231860_at	-0.294	5.417	-2.393	3.002e-02	0.488	-3.602	BRWD1	bromodomain and WD repeat domain containing 1	21	-39590234, -39484017, -39479273	AW268572	54014	21q22.2	Hs.654740	8	protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter biological_process transcription regulator activity regulation of transcription
201005_at	0.563	8.565	2.393	3.005e-02	0.488	-3.603	CD9	CD9 molecule	12	6179815	NM_001769	928	12p13.3	Hs.114286	96	protein binding plasma membrane plasma membrane integral to plasma membrane cell motion cell adhesion fusion of sperm to egg plasma membrane platelet activation paranodal junction assembly platelet alpha granule membrane	Hematopoietic cell lineage
218998_at	-0.295	7.265	-2.393	3.005e-02	0.488	-3.603	C9orf6	chromosome 9 open reading frame 6	9	110736493	NM_017832	54942	9q31.3	Hs.29276	2
203374_s_at	-0.305	7.165	-2.392	3.007e-02	0.488	-3.604	TPP2	tripeptidyl peptidase II	13	102047286	AW612376	7174	13q32-q33	Hs.432424	23	aminopeptidase activity serine-type endopeptidase activity cytoplasm proteolysis peptidase activity tripeptidyl-peptidase activity
201539_s_at	-0.746	11.817	-2.392	3.008e-02	0.488	-3.604	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	U29538	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
1554770_x_at	0.309	2.991	2.392	3.008e-02	0.488	-3.604	ZNF785	zinc finger protein 785	16	-30499494	BC040642	146540	16p11.2	Hs.513509	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235030_at	-0.349	6.982	-2.392	3.010e-02	0.488	-3.605	FAM55C	family with sequence similarity 55, member C	3	102980718, 102980975	BF969254	91775	3q12.3	Hs.595933	4	extracellular region
213391_at	0.338	6.242	2.392	3.011e-02	0.488	-3.605	DPY19L4	dpy-19-like 4 (C. elegans)	8	95801278	AI669947	286148	8q22.1	Hs.567828	6	membrane integral to membrane
202234_s_at	-0.451	7.965	-2.391	3.012e-02	0.488	-3.605	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	BF511091	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
222071_s_at	-0.189	2.426	-2.391	3.013e-02	0.488	-3.605	SLCO4C1	solute carrier organic anion transporter family, member 4C1	5	-101597590	BE552428	353189	5q21.2	Hs.127648	2	transporter activity plasma membrane ion transport multicellular organismal development spermatogenesis integral to membrane cell differentiation
203315_at	-0.251	8.167	-2.391	3.014e-02	0.488	-3.606	NCK2	NCK adaptor protein 2	2	105727785, 105834736	BC000103	8440	2q12	Hs.529244 Hs.707062	34	protein binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal transduction signal complex assembly epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor activity cytoskeletal adaptor activity negative regulation of cell proliferation vesicle membrane cell migration lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
204811_s_at	0.270	6.104	2.391	3.016e-02	0.488	-3.606	CACNA2D2	calcium channel, voltage-dependent, alpha 2/delta subunit 2	3	-50375234	NM_006030	9254	3p21.3	Hs.476273 Hs.674666	9	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
217292_at	-0.182	2.190	-2.391	3.017e-02	0.488	-3.606	MTMR7	myotubularin related protein 7	8	-17198676	AL117549	9108	8p22	Hs.625674	6	inositol or phosphatidylinositol phosphatase activity protein tyrosine phosphatase activity protein binding membrane fraction cytoplasm cytosol protein amino acid dephosphorylation hydrolase activity
230367_at	-1.313	9.957	-2.390	3.022e-02	0.489	-3.608	SMTNL1	smoothelin-like 1	11	57065554	AI359511	219537	11q12.1	Hs.68756	2	response to activity peptidyl-serine phosphorylation M band I band response to drug contractile fiber positive regulation of vasoconstriction negative regulation of vasodilation muscle organ morphogenesis
205130_at	0.236	4.763	2.389	3.025e-02	0.489	-3.609	RAGE	renal tumor antigen	14	-101764930	NM_014226	5891	14q32	Hs.104119	67	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation signal transduction transferase activity
203192_at	-0.321	6.466	-2.389	3.026e-02	0.489	-3.609	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6	2	-219782737	NM_005689	10058	2q36	Hs.107911	15	nucleotide binding ATP binding mitochondrion mitochondrial envelope mitochondrial outer membrane transport cellular iron ion homeostasis membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters
225840_at	-0.415	7.277	-2.389	3.026e-02	0.489	-3.609	TEF	thyrotrophic embryonic factor	22	40093337, 40107908	AA779795	7008	22q13 22q13.2	Hs.181159	14	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity rhythmic process
224991_at	0.273	4.888	2.389	3.028e-02	0.489	-3.610	CMIP	c-Maf-inducing protein	16	80036275, 80086454	AI819630	80790	16q23	Hs.709248	7	nucleus cytoplasm
200767_s_at	-0.212	7.277	-2.388	3.031e-02	0.489	-3.611	FAM120A	family with sequence similarity 120A	9	95253993	NM_014612	23196	9q22.31	Hs.372003 Hs.707324	14	RNA binding cytoplasm plasma membrane
215984_s_at	-0.252	6.251	-2.388	3.034e-02	0.489	-3.611	ARFRP1	ADP-ribosylation factor related protein 1	20	-61800439	AL121845	10139	20q13.3	Hs.389277	12	nucleotide binding GTPase activity GTP binding intracellular membrane fraction Golgi apparatus signal transduction small GTPase mediated signal transduction gastrulation
1569894_at	0.336	4.641	2.388	3.035e-02	0.489	-3.612	PPP2R3C	protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma	14	-34624428	BC037797	55012	14q13.2	Hs.530712 Hs.621667	8	calcium ion binding protein binding nucleus cytoplasm
232147_at	0.181	6.059	2.387	3.037e-02	0.489	-3.612	BTBD12	BTB (POZ) domain containing 12	16	-3571183	AL442083	84464	16p13.3	Hs.143681	8	protein binding
226595_at	0.203	6.249	2.387	3.039e-02	0.490	-3.613	SNX21	sorting nexin family member 21	20	43895876	AI935964	90203	20q13.12	Hs.472854	8	protein binding cell communication protein transport phosphoinositide binding
242338_at	-0.264	4.707	-2.386	3.042e-02	0.490	-3.614	TMEM64	transmembrane protein 64	8	-91703398	BG535396	169200	8q21.3	Hs.567759	2	membrane integral to membrane
45714_at	-0.754	9.104	-2.386	3.043e-02	0.490	-3.614	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)	16	-3012626	AA436930	54985	16p13.3	Hs.719259	2	nucleus cytoplasm
239730_at	-0.241	5.238	-2.386	3.046e-02	0.490	-3.615	DGCR14	DiGeorge syndrome critical region gene 14	22	-17497791	AA662761	8220	22q11.2 22q11.21	Hs.517407 Hs.716675	17	molecular_function nucleus spliceosomal complex nucleolus cytoplasm mRNA processing nervous system development RNA splicing
229752_at	0.349	6.321	2.386	3.046e-02	0.490	-3.615	IKZF4	IKAROS family zinc finger 4 (Eos)	12	54700955	BF115531	64375	12q13	Hs.553221	9	transcription factor activity intracellular nucleus zinc ion binding transcription repressor activity regulation of transcription metal ion binding
201189_s_at	0.208	6.302	2.386	3.046e-02	0.490	-3.615	ITPR3	inositol 1,4,5-triphosphate receptor, type 3	6	33697138	NM_002224	3710	6p21	Hs.65758	40	inositol hexakisphosphate binding ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding protein binding nucleus nuclear outer membrane nucleoplasm nucleolus cytoplasm endoplasmic reticulum microsome integral to plasma membrane brush border ion transport calcium ion transport G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration membrane phosphoinositide binding cell soma myelin sheath inositol 1,3,4,5 tetrakisphosphate binding apical part of cell sensory perception of bitter taste sensory perception of sweet taste sensory perception of umami taste protein homooligomerization protein heterooligomerization response to calcium ion inositol 1,4,5 trisphosphate binding	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression Taste transduction GnRH signaling pathway Alzheimer's disease
210886_x_at	0.288	6.997	2.386	3.046e-02	0.490	-3.615	TP53TG1	TP53 target 1 (non-protein coding)	7	-86792599	AB007457	11257	7q21.1	Hs.274329	3	signal transducer activity response to stress
202222_s_at	-0.249	11.468	-2.385	3.049e-02	0.490	-3.616	DES	desmin	2	219991342	NM_001927	1674	2q35	Hs.594952	57	structural constituent of cytoskeleton protein binding intracellular insoluble fraction cytoplasm cytoskeleton muscle contraction cytoskeleton organization regulation of heart contraction Z disc sarcolemma contractile fiber type III intermediate filament synapse	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
230739_at	-0.328	8.015	-2.385	3.049e-02	0.490	-3.616	C18orf19	chromosome 18 open reading frame 19	18	-13653345	AI192379	125228	18p11.21	Hs.13034	3	membrane integral to membrane
222936_s_at	-0.222	2.867	-2.385	3.052e-02	0.490	-3.617	PPPDE1	PPPDE peptidase domain containing 1	1	242882974	AF151904	51029	1q44	Hs.498317	5
229247_at	0.232	4.873	2.385	3.053e-02	0.490	-3.617	FBLN7	fibulin 7	2	112612432	BE677799	129804	2q13	Hs.437696	5	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix cell adhesion heparin binding
200059_s_at	-0.299	10.457	-2.385	3.053e-02	0.490	-3.617	RHOA	ras homolog gene family, member A	3	-49371582	BC001360	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
220266_s_at	-0.338	5.360	-2.384	3.054e-02	0.490	-3.617	KLF4	Kruppel-like factor 4 (gut)	9	-109286953	NM_004235	9314	9q31	Hs.376206	66	transcription factor activity intracellular nucleus nucleolus mesodermal cell fate determination zinc ion binding negative regulation of cell proliferation transcription activator activity transcription repressor activity regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding
212095_s_at	-0.331	7.019	-2.384	3.056e-02	0.490	-3.618	MTUS1	mitochondrial tumor suppressor 1	8	-17545583, -17545583, -17545583	BE552421	57509	8p22	Hs.7946	11	nucleus mitochondrion Golgi apparatus plasma membrane
219199_at	-0.338	3.674	-2.384	3.058e-02	0.490	-3.618	AFF4	AF4/FMR2 family, member 4	5	-132238969	NM_014423	27125	5q31	Hs.519313 Hs.664840	10	transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription
222688_at	0.385	4.216	2.384	3.058e-02	0.490	-3.618	ACER3	alkaline ceramidase 3	11	76249564	R12678	55331	11q13.5	Hs.23862	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ceramide metabolic process membrane integral to membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	Sphingolipid metabolism
210305_at	-0.738	11.233	-2.384	3.059e-02	0.490	-3.619	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	AB042557	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
1565681_s_at	-0.391	6.440	-2.384	3.059e-02	0.490	-3.619	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	10	-310131	N42910	22982	10p15.3	Hs.432397	7	catalytic activity nucleus transcription factor binding metabolic process
204508_s_at	-0.219	3.892	-2.383	3.060e-02	0.490	-3.619	CA12	carbonic anhydrase XII	15	-61402782	BC001012	771	15q22	Hs.210995	27	carbonate dehydratase activity cytoplasm plasma membrane one-carbon metabolic process zinc ion binding integral to membrane lyase activity metal ion binding	Nitrogen metabolism
223581_at	0.235	5.041	2.383	3.061e-02	0.490	-3.619	ZNF577	zinc finger protein 577	19	-57066361, -57066361, -57050868	BC004992	84765	19q13.41	Hs.148322	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218601_at	0.187	8.240	2.383	3.062e-02	0.490	-3.619	URG4	up-regulated gene 4	7	-43882025, -43882025	NM_017920	55665	7p13	Hs.709317	9
1565716_at	0.332	5.339	2.382	3.069e-02	0.491	-3.622	FUS	fusion (involved in t(12;16) in malignant liposarcoma)	16	31098953	BE930017	2521	16p11.2	Hs.513522	55	nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding intracellular nucleus nucleolus cell death zinc ion binding metal ion binding
212926_at	-0.395	4.594	-2.382	3.070e-02	0.491	-3.622	SMC5	structural maintenance of chromosomes 5	9	72063697	AW183677	23137	9q21.12	Hs.534189 Hs.601181	13	nucleotide binding ATP binding nucleus chromosome DNA repair DNA recombination response to DNA damage stimulus
202472_at	0.271	6.465	2.382	3.070e-02	0.491	-3.622	MPI	mannose phosphate isomerase	15	72969462	NM_002435	4351	15q22-qter	Hs.75694	18	mannose-6-phosphate isomerase activity cytoplasm carbohydrate metabolic process zinc ion binding isomerase activity metal ion binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
237475_x_at	0.211	8.236	2.382	3.070e-02	0.491	-3.622	CCDC152	coiled-coil domain containing 152	5	42792676	AI151104	100129792	5p12	Hs.718521	1
230700_at	-0.277	5.276	-2.381	3.073e-02	0.491	-3.623	RTN4RL1	reticulon 4 receptor-like 1	17	-1784720	H06251	146760	17p13.3	Hs.22917	5	receptor activity protein binding plasma membrane axon regeneration anchored to plasma membrane
225521_at	-0.373	5.871	-2.381	3.075e-02	0.491	-3.623	ANAPC7	anaphase promoting complex subunit 7	12	-109297656, -109295087	AL137586	51434	12q24.11	Hs.524741	30	binding nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
1568834_s_at	0.268	5.705	2.381	3.075e-02	0.491	-3.623	CCDC90B	coiled-coil domain containing 90B	11	-82650149	BC017771	60492	11q14.1	Hs.368866	7	mitochondrion membrane integral to membrane
1564207_at	-0.356	7.969	-2.381	3.076e-02	0.491	-3.623	FLJ35390	hypothetical LOC255031	7	44045222, 44045591	BC014556	255031	7p13	Hs.633978 Hs.661253	3
202482_x_at	-0.215	5.175	-2.380	3.079e-02	0.491	-3.624	RANBP1	RAN binding protein 1	22	18485023	AI862473	5902	22q11.21	Hs.24763	24	GDP-dissociation inhibitor activity GTPase activator activity protein binding nucleus cytoplasm centrosome spindle organization signal transduction Ran GTPase binding positive regulation of mitotic centrosome separation intracellular transport
238864_at	0.224	5.488	2.380	3.080e-02	0.491	-3.624	VWA3A	von Willebrand factor A domain containing 3A	16	22011363	AI559649	146177	16p12.2	Hs.10697	4	extracellular region
223053_x_at	-0.235	8.527	-2.380	3.081e-02	0.491	-3.625	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	AF277178	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
1566271_x_at	-0.185	3.442	-2.380	3.083e-02	0.491	-3.625	GARNL1	GTPase activating Rap/RanGAP domain-like 1	14	-35077308	AF085938	253959	14q13.2	Hs.113150	10	GTPase activator activity intracellular nucleus cytoplasm mitochondrion regulation of small GTPase mediated signal transduction
208803_s_at	-0.398	5.248	-2.379	3.086e-02	0.491	-3.626	SRP72	signal recognition particle 72kDa	4	57028518	AF069765	6731	4q11	Hs.237825	18	signal recognition particle binding binding cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane 7S RNA binding response to drug	Protein export
1555758_a_at	0.371	4.726	2.378	3.090e-02	0.492	-3.627	CDKN3	cyclin-dependent kinase inhibitor 3	14	53933422	AF213040	1033	14q22	Hs.84113	17	regulation of cyclin-dependent protein kinase activity G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein binding cytoplasm cell cycle cell cycle arrest protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation dephosphorylation hydrolase activity perinuclear region of cytoplasm
1560163_at	0.230	4.092	2.378	3.091e-02	0.492	-3.628	LOC100129510	hypothetical protein LOC100129510	17		AK097908	100129510	17q25.3	Hs.656230	1
226573_at	0.571	5.920	2.377	3.097e-02	0.492	-3.629	DIRAS1	DIRAS family, GTP-binding RAS-like 1	19	-2665564	AI829795	148252	19p13.3	Hs.172753	6	nucleotide binding GTP binding intracellular plasma membrane small GTPase mediated signal transduction
201149_s_at	0.583	8.493	2.377	3.098e-02	0.492	-3.630	TIMP3	TIMP metallopeptidase inhibitor 3	22	31526801	U67195	7078	22q12.1-q13.2 22q12.3	Hs.644633 Hs.714168	117	enzyme inhibitor activity protein binding extracellular region basement membrane visual perception metalloendopeptidase inhibitor activity response to organic cyclic substance tissue regeneration response to estrogen stimulus response to stimulus negative regulation of membrane protein ectodomain proteolysis
1555271_a_at	0.231	5.059	2.377	3.099e-02	0.492	-3.630	TERT	telomerase reverse transcriptase	5	-1306286	AB085628	7015	5p15.33	Hs.492203	518	telomere maintenance chromosome, telomeric region nuclear telomere cap complex DNA binding telomeric template RNA reverse transcriptase activity protein binding nucleus nucleoplasm chromosome telomerase holoenzyme complex anti-apoptosis telomere maintenance via telomerase senescence transferase activity nucleotidyltransferase activity DNA strand elongation telomere formation via telomerase telomeric DNA binding protein homodimerization activity telomeric RNA binding
220300_at	0.432	4.919	2.377	3.099e-02	0.492	-3.630	RGS3	regulator of G-protein signaling 3	9	115246831, 115265829, 115303527, 115367181, 115382760, 115396020	NM_017790	5998	9q32	Hs.494875	24	inactivation of MAPK activity signal transducer activity GTPase activator activity protein binding nucleus cytoplasm cytosol plasma membrane regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction	Axon guidance
203781_at	0.207	11.411	2.377	3.101e-02	0.492	-3.630	MRPL33	mitochondrial ribosomal protein L33	2	27848087	NM_004891	9553	2p21	Hs.515879	8	structural constituent of ribosome intracellular mitochondrion ribosome translation
236514_at	0.492	5.262	2.377	3.101e-02	0.492	-3.631	ACOT8	acyl-CoA thioesterase 8	20	-43903767	AI885067	10005	20q13.12	Hs.444776	18	carboxylesterase activity protein binding peroxisome lipid metabolic process acyl-CoA metabolic process peroxisome organization acyl-CoA thioesterase activity hydrolase activity choloyl-CoA hydrolase activity interspecies interaction between organisms
201514_s_at	-0.527	6.900	-2.376	3.106e-02	0.493	-3.632	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	NM_005754	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
223193_x_at	0.272	10.789	2.376	3.107e-02	0.493	-3.632	FAM162A	family with sequence similarity 162, member A	3	123585712	AF201944	26355	3q21.1	Hs.584881	8	membrane integral to membrane
1553693_s_at	0.356	5.173	2.375	3.108e-02	0.493	-3.632	CBR4	carbonyl reductase 4	4	-170145316	NM_032783	84869	4q32.3	Hs.659311	4	binding cytoplasm oxidoreductase activity oxidation reduction
212018_s_at	-0.381	8.731	-2.375	3.108e-02	0.493	-3.633	RSL1D1	ribosomal L1 domain containing 1	16	-11835555	AK000822	26156	16p13.13	Hs.401842	17	RNA binding structural constituent of ribosome protein binding intracellular nucleus nucleolus ribosome RNA processing translation regulation of protein localization
206976_s_at	-0.477	8.022	-2.375	3.113e-02	0.493	-3.634	HSPH1	heat shock 105kDa/110kDa protein 1	13	-30608762	NM_006644	10808	13q12.3	Hs.36927	25	nucleotide binding ATP binding cytoplasm response to unfolded protein
207001_x_at	-0.340	6.615	-2.375	3.113e-02	0.493	-3.634	TSC22D3	TSC22 domain family, member 3	X	-106843107, -106843107, -106843107	NM_004089	1831	Xq22.3	Hs.716410	24	transcription factor activity regulation of transcription, DNA-dependent
212149_at	-0.334	9.238	-2.375	3.113e-02	0.493	-3.634	EFR3A	EFR3 homolog A (S. cerevisiae)	8	132985540	AW470003	23167	8q24.22	Hs.204564	4	binding plasma membrane
205990_s_at	0.414	6.131	2.375	3.114e-02	0.493	-3.634	WNT5A	wingless-type MMTV integration site family, member 5A	3	-55474782	NM_003392	7474	3p21-p14	Hs.696364	68	signal transducer activity receptor binding extracellular region proteinaceous extracellular matrix extracellular space soluble fraction signal transduction Wnt receptor signaling pathway, calcium modulating pathway JNK cascade cell-cell signaling anatomical structure morphogenesis embryonic development cell differentiation lung development embryonic limb morphogenesis cartilage development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
206391_at	0.265	4.967	2.373	3.123e-02	0.494	-3.637	RARRES1	retinoic acid receptor responder (tazarotene induced) 1	3	-159905133, -159897590	NM_002888	5918	3q25.32	Hs.131269	11	negative regulation of cell proliferation membrane integral to membrane
226750_at	-0.419	6.597	-2.373	3.124e-02	0.494	-3.637	LARP1B	La ribonucleoprotein domain family, member 1B	4	129201952, 129201952, 129201952	AI767732	55132	4q28.2	Hs.657067	3	RNA binding
232337_at	-0.187	3.934	-2.372	3.129e-02	0.495	-3.638	B3GNT7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	2	231968578	AK000770	93010	2q37.1	Hs.299329	4	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups	Keratan sulfate biosynthesis Metabolic pathways
203687_at	-0.288	6.533	-2.372	3.129e-02	0.495	-3.638	CX3CL1	chemokine (C-X3-C motif) ligand 1	16	55963914	NM_002996	6376	16q13	Hs.531668	100	extracellular region extracellular space plasma membrane chemotaxis defense response immune response cell adhesion chemokine activity cell surface integral to membrane cytokine-mediated signaling pathway leukocyte chemotaxis positive regulation of inflammatory response leukocyte adhesive activation positive regulation of calcium-independent cell-cell adhesion	Cytokine-cytokine receptor interaction Chemokine signaling pathway
225717_at	-0.567	6.412	-2.371	3.133e-02	0.495	-3.639	KIAA1715	KIAA1715	2	-176498655	AI814587	80856	2q31	Hs.209561	7	protein binding multicellular organismal development membrane integral to membrane limb development
228055_at	0.309	4.243	2.371	3.138e-02	0.495	-3.641	NAPSB	napsin B aspartic peptidase pseudogene	19	-55528868	AI763426	256236	19q13.33	Hs.636624	4
227666_at	0.177	4.735	2.370	3.139e-02	0.495	-3.641	DCLK2	doublecortin-like kinase 2	4	151219529	AI523594	166614	4q31.23-q31.3	Hs.591683	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation intracellular signaling cascade transferase activity
1562650_at	-0.175	3.069	-2.370	3.140e-02	0.495	-3.641	FRYL	FRY-like	4	-48194136	AL833444	285527	4p11	Hs.631525	8	protein binding regulation of transcription
208541_x_at	-0.205	6.752	-2.370	3.141e-02	0.495	-3.642	TFAM	transcription factor A, mitochondrial	10	59815181	NM_012251	7019	10q21	Hs.642966	50	transcription factor activity nucleus mitochondrion DNA-dependent DNA replication regulation of transcription from RNA polymerase I promoter transcription from mitochondrial promoter mitochondrial nucleoid regulation of transcription	Huntington's disease
208522_s_at	0.229	4.865	2.370	3.142e-02	0.495	-3.642	PTCH1	patched homolog 1 (Drosophila)	9	-97245084, -97245084, -97245084, -97245084, -97245084	NM_000264	5727	9q22.3	Hs.494538 Hs.638946	96	receptor activity protein binding integral to plasma membrane signal transduction hedgehog receptor activity cell proliferation regulation of smoothened signaling pathway organ morphogenesis dorsal/ventral pattern formation membrane protein processing embryonic limb morphogenesis negative regulation of multicellular organism growth	Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma
1555214_a_at	0.209	3.808	2.370	3.143e-02	0.495	-3.642	CLEC7A	C-type lectin domain family 7, member A	12	-10171188, -10160646	AF400602	64581	12p13.2	Hs.143929	30	binding sugar binding cytoplasm phagocytosis, recognition inflammatory response pattern recognition receptor activity carbohydrate mediated signaling membrane integral to membrane T cell activation MHC protein binding defense response to protozoan innate immune response
223394_at	-0.352	6.703	-2.370	3.144e-02	0.495	-3.642	SERTAD1	SERTA domain containing 1	19	-45620248	BC002670	29950	19q13.1-q13.2	Hs.269898	15	regulation of cyclin-dependent protein kinase activity protein binding positive regulation of cell proliferation transcription activator activity positive regulation of transcription
211838_x_at	-0.173	5.124	-2.370	3.144e-02	0.495	-3.643	PCDHA5	protocadherin alpha 5	5	140181544, 140181544	AF152483	56143	5q31	Hs.199343	10	calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion nervous system development
212291_at	0.361	4.346	2.369	3.146e-02	0.495	-3.643	HIPK1	homeodomain interacting protein kinase 1	1	114273518, 114273518, 114295289, 114298021	AI393355	204851	1p13.2	Hs.532363	11	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleolus cytoplasm centrosome protein amino acid phosphorylation transferase activity regulation of transcription
233242_at	-0.232	4.321	-2.369	3.146e-02	0.495	-3.643	WDR73	WD repeat domain 73	15	-82987014	AL357213	84942	15q25.2	Hs.719288	3
219901_at	0.375	4.578	2.369	3.148e-02	0.495	-3.644	FGD6	FYVE, RhoGEF and PH domain containing 6	12	-93994655	NM_018351	55785	12q22	Hs.506381	6	ruffle guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm Golgi apparatus cytoskeleton zinc ion binding regulation of cell shape lamellipodium actin cytoskeleton organization small GTPase binding regulation of Rho protein signal transduction regulation of Cdc42 GTPase activity filopodium assembly metal ion binding
233880_at	0.218	4.869	2.369	3.148e-02	0.495	-3.644	RNF213	ring finger protein 213	17	75928320	AL161961	57674	17q25.3	Hs.195642 Hs.657519	6	nucleotide binding protein binding zinc ion binding nucleoside-triphosphatase activity metal ion binding
221505_at	-0.268	8.351	-2.369	3.150e-02	0.495	-3.644	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	1	-148457341, -148457341	AW612574	81611	1q21.2	Hs.656466	14	protein binding nucleus cytoplasm cytoplasmic membrane-bounded vesicle phosphatase inhibitor activity
1565765_x_at	0.171	3.379	2.369	3.151e-02	0.495	-3.644	C13orf33	chromosome 13 open reading frame 33	13	30378311	AL832478	84935	13q12.3	Hs.646647 Hs.708377	4
221191_at	0.195	4.968	2.368	3.151e-02	0.495	-3.644	STAG3L1	stromal antigen 3-like 1	7	74826382	NM_018991	54441	7q11.23-q21.1	Hs.632310 Hs.661254 Hs.709564	2
203798_s_at	-0.361	2.981	-2.368	3.152e-02	0.495	-3.645	VSNL1	visinin-like 1	2	17585287	NM_003385	7447	2p24.3	Hs.444212	29	calcium ion binding
209132_s_at	0.336	6.451	2.368	3.154e-02	0.495	-3.645	COMMD4	COMM domain containing 4	15	73415426	BE313890	54939	15q24.2	Hs.351327	8	protein binding cytoplasm
1555603_at	0.194	2.416	2.368	3.155e-02	0.495	-3.646	BAGE	B melanoma antigen	21	-10079666	AF527551	574	21p11.1	Hs.545789 Hs.624542 Hs.624543	7	extracellular region
226319_s_at	0.301	7.666	2.368	3.156e-02	0.495	-3.646	THOC4	THO complex 4	17	-77439008	AF047002	10189	17q25.3	Hs.534385	26	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex cytoplasm transport RNA splicing nuclear speck mRNA transport
235616_at	0.231	4.398	2.367	3.157e-02	0.495	-3.646	TSHZ2	teashirt zinc finger homeobox 2	20	51022283	AI694059	128553	20q13.2	Hs.271605 Hs.473117 Hs.649877	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding
209568_s_at	0.362	6.717	2.367	3.157e-02	0.495	-3.646	RGL1	ral guanine nucleotide dissociation stimulator-like 1	1	181871830	AF186779	23179	1q25.3	Hs.497148	6	guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular signal transduction Ral guanyl-nucleotide exchange factor activity regulation of small GTPase mediated signal transduction
1555814_a_at	-0.354	9.327	-2.367	3.158e-02	0.495	-3.646	RHOA	ras homolog gene family, member A	3	-49371582	AF498970	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
227798_at	0.375	7.699	2.367	3.162e-02	0.495	-3.647	SMAD1	SMAD family member 1	4	146622400, 146623406	AU146891	4086	4q31	Hs.604588	118	MAPKKK cascade mesodermal cell fate commitment osteoblast fate commitment transcription factor activity RNA polymerase II transcription factor activity receptor signaling protein activity intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol inflammatory response signal transduction transforming growth factor beta receptor signaling pathway SMAD protein complex assembly gamete generation negative regulation of cell proliferation embryonic pattern specification positive regulation of gene expression integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity midbrain development hindbrain development primary microRNA processing homeostatic process identical protein binding positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter co-SMAD binding	TGF-beta signaling pathway
1561660_at	-0.276	2.591	-2.367	3.162e-02	0.495	-3.647	MCART6	mitochondrial carrier triple repeat 6	X	-103230553	AL833609	401612	Xq22.2	Hs.660022	1	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
207910_at	0.229	3.144	2.366	3.166e-02	0.495	-3.648	SCGB1D1	secretoglobin, family 1D, member 1	11	61714285	NM_006552	10648	11q13	Hs.202686	4	binding extracellular region extracellular space
206993_at	0.533	7.515	2.366	3.166e-02	0.495	-3.649	ATP5S	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)	14	49848796, 49848796	NM_015684	27109	14q21.3	Hs.438489	12	mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o)
221810_at	0.296	5.284	2.366	3.168e-02	0.495	-3.649	RAB15	RAB15, member RAS onocogene family	14	-64482284	AA631242	376267	14q23.3	Hs.512492	11	nucleotide binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport
225998_at	-0.671	5.872	-2.366	3.169e-02	0.495	-3.649	GAB1	GRB2-associated binding protein 1	4	144477432	AK022142	2549	4q31.21	Hs.618456 Hs.80720	69	SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway	ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma
202822_at	0.351	7.884	2.365	3.173e-02	0.496	-3.650	LPP	LIM domain containing preferred translocation partner in lipoma	3	189413414	BF221852	4026	3q28	Hs.444362	30	molecular_function protein binding cellular_component nucleus cytoplasm plasma membrane focal adhesion cell adhesion biological_process zinc ion binding cell junction metal ion binding
228046_at	0.336	7.204	2.364	3.181e-02	0.497	-3.653	ZNF827	zinc finger protein 827	4	-146901337	AA741243	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
226985_at	0.229	5.909	2.362	3.189e-02	0.497	-3.655	FGD5	FYVE, RhoGEF and PH domain containing 5	3	14835472	AW269340	152273	3p25.1	Hs.412406	4	ruffle guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm Golgi apparatus cytoskeleton zinc ion binding regulation of cell shape lamellipodium actin cytoskeleton organization small GTPase binding regulation of Rho protein signal transduction regulation of Cdc42 GTPase activity filopodium assembly metal ion binding
220173_at	0.302	4.762	2.362	3.192e-02	0.498	-3.656	C14orf45	chromosome 14 open reading frame 45	14	73555811	NM_025057	80127	14q24.3	Hs.644621	5
204156_at	0.335	5.842	2.361	3.194e-02	0.498	-3.656	QSK	serine/threonine-protein kinase QSK	11	-116219327	AA044154	23387	11q23.3	Hs.167451	14	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
234956_at	-0.250	5.402	-2.361	3.197e-02	0.498	-3.657	LOC93444	hypothetical protein LOC93444	15		AK000175	93444	15q22.32	Hs.270133
214183_s_at	0.542	4.083	2.361	3.199e-02	0.498	-3.657	TKTL1	transketolase-like 1	X	153177220, 153186602	X91817	8277	Xq28	Hs.102866	21	transketolase activity calcium ion binding nucleus cytoplasm glucose catabolic process thiamin metabolic process metabolic process transferase activity	Pentose phosphate pathway Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of plant hormones Metabolic pathways
227416_s_at	0.205	9.919	2.360	3.203e-02	0.498	-3.659	ZCRB1	zinc finger CCHC-type and RNA binding motif 1	12	-40992154	BE265803	85437	12q12	Hs.496279	5	nucleotide binding RNA binding nucleus nucleoplasm U12-type spliceosomal complex mRNA processing zinc ion binding RNA splicing metal ion binding
1558846_at	0.247	2.802	2.360	3.204e-02	0.498	-3.659	PNLIPRP3	pancreatic lipase-related protein 3	10	118177413	AL833418	119548	10q25.3	Hs.276724	1	triacylglycerol lipase activity extracellular region lipid catabolic process hydrolase activity
223019_at	0.231	6.214	2.360	3.205e-02	0.498	-3.659	FAM129B	family with sequence similarity 129, member B	9	-129307438, -129307438	BC001979	64855	9q33.3-q34.11	Hs.522401	8
236605_at	0.206	5.721	2.360	3.206e-02	0.498	-3.659	EIF3K	eukaryotic translation initiation factor 3, subunit K	19	43801561	AA470798	27335	19q13.2	Hs.314359	15	translation initiation factor activity translation initiation factor activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex regulation of translational initiation ribosome binding
1562403_a_at	-0.359	7.147	-2.359	3.207e-02	0.498	-3.660	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3	14	-69580686, -69580686, -69580686	AK096553	6547	14q24.1	Hs.337696	16	calcium:sodium antiporter activity calcium ion binding calmodulin binding ion transport sodium ion transport calcium ion transport cell communication antiporter activity membrane integral to membrane sodium ion binding	Calcium signaling pathway
203191_at	-0.252	5.297	-2.359	3.208e-02	0.498	-3.660	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6	2	-219782737	AF308472	10058	2q36	Hs.107911	15	nucleotide binding ATP binding mitochondrion mitochondrial envelope mitochondrial outer membrane transport cellular iron ion homeostasis membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters
222629_at	0.485	5.370	2.359	3.209e-02	0.498	-3.660	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	N51427	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
221912_s_at	0.427	8.726	2.359	3.210e-02	0.498	-3.660	CCDC28B	coiled-coil domain containing 28B	1	32438788	AL049795	79140	1p35.1	Hs.718470	10
1568629_s_at	0.237	7.774	2.358	3.214e-02	0.499	-3.662	PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	19	18125015	BC033311	5296	19q13.2-q13.4	Hs.371344	68	protein binding intracellular cytosol phosphoinositide 3-kinase complex signal transduction 1-phosphatidylinositol-3-kinase activity negative regulation of anti-apoptosis phosphoinositide 3-kinase regulator activity	ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
212049_at	0.207	6.240	2.358	3.215e-02	0.499	-3.662	WIPF2	WAS/WASL interacting protein family, member 2	17	35629099	BG230612	147179	17q21.1-q21.2	Hs.421622 Hs.705989	11	actin binding cytoplasm cytoskeleton
243346_at	-0.366	9.852	-2.358	3.215e-02	0.499	-3.662	LMOD3	leiomodin 3 (fetal)	3	-69238728	BF109621	56203	3p14.1	Hs.350621	9	tropomyosin binding cytoplasm cytoskeleton
200045_at	-0.292	8.182	-2.358	3.217e-02	0.499	-3.662	ABCF1	ATP-binding cassette, sub-family F (GCN20), member 1	6	30647148, 1987727, 1786022	NM_001090	23	6p21.33	Hs.655285	15	nucleotide binding ATP binding translation inflammatory response translation factor activity, nucleic acid binding ATPase activity ATPase activity, coupled to transmembrane movement of substances
203642_s_at	0.333	4.977	2.358	3.218e-02	0.499	-3.663	COBLL1	COBL-like 1	2	-165249503	NM_014900	22837	2q24.3	Hs.470457	9
225805_at	-0.389	5.331	-2.357	3.221e-02	0.499	-3.664	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	AW137669	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
211033_s_at	0.393	7.209	2.357	3.221e-02	0.499	-3.664	PEX7	peroxisomal biogenesis factor 7	6	137185394	BC006268	5191	6q23.3	Hs.280932	21	peroxisome matrix targeting signal-2 binding cytoplasm peroxisome visual perception ether lipid biosynthetic process protein transport protein import into peroxisome matrix response to stimulus
1563426_a_at	0.307	4.127	2.357	3.222e-02	0.499	-3.664	LOC644613	hypothetical protein LOC644613	11		BC025792	644613	11q13.1	Hs.604039	1
235822_at	0.375	6.208	2.357	3.223e-02	0.499	-3.664	COQ9	coenzyme Q9 homolog (S. cerevisiae)	16	56038902	AW273049	57017	16q21	Hs.513632	7	mitochondrion ubiquinone biosynthetic process
1553023_a_at	-0.198	4.054	-2.357	3.224e-02	0.499	-3.664	NOX5	NADPH oxidase, EF-hand calcium binding domain 5	15	67009917	NM_024505	79400	15q23	Hs.657932	27	cytokinesis ion channel activity calcium ion binding ion transport induction of apoptosis cell proliferation electron carrier activity regulation of proton transport hydrogen ion channel activity hydrogen ion channel activity membrane integral to membrane superoxide-generating NADPH oxidase activity superoxide-generating NADPH oxidase activity oxidoreductase activity heme binding electron transport chain superoxide anion generation superoxide anion generation regulation of fusion of sperm to egg plasma membrane FAD binding NADP or NADPH binding cytokine secretion
1564637_a_at	0.268	7.701	2.357	3.224e-02	0.499	-3.664	FAM98B	family with sequence similarity 98, member B	15	36533619, 36533619	BC035600	283742	15q14	Hs.6799	5	protein binding
1559651_at	-0.240	2.712	-2.357	3.225e-02	0.499	-3.665	CSNK1A1P	casein kinase 1, alpha 1 pseudogene	15	-34878593	BC028192	161635	15q14	Hs.659822	1
207570_at	0.229	5.913	2.356	3.227e-02	0.499	-3.665	SHOX	short stature homeobox	X, Y	505078, 505078, 505078, 505078	NM_000451	6473	Xp22.33 Yp11.3	Hs.105932	48	skeletal system development transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter multicellular organismal development sequence-specific DNA binding
205913_at	0.644	5.958	2.356	3.227e-02	0.499	-3.665	PLIN1	perilipin 1	15	-88008602	NM_002666	5346	15q26	Hs.103253	42	protein binding lipid binding monolayer-surrounded lipid storage body lipid catabolic process	PPAR signaling pathway
209149_s_at	0.226	5.555	2.356	3.229e-02	0.499	-3.666	TM9SF1	transmembrane 9 superfamily member 1	14	-23729083, -23728192	BE899402	10548	14q11.2	Hs.91586	5	membrane integral to membrane
224690_at	0.516	9.832	2.356	3.230e-02	0.499	-3.666	C20orf108	chromosome 20 open reading frame 108	20	54367389	BG432350	116151	20q13.2	Hs.143736 Hs.593629	6	membrane integral to membrane
227933_at	-0.246	5.081	-2.356	3.232e-02	0.499	-3.666	LINGO1	leucine rich repeat and Ig domain containing 1	15	-75692423	AI193252	84894	15q24.3	Hs.656765	14
229854_at	0.274	9.795	2.356	3.232e-02	0.499	-3.666	OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	1	226462483, 226462483	AW614056	84033	1q42.13	Hs.650039 Hs.656999	23	nucleotide binding magnesium ion binding protein serine/threonine kinase activity Rho guanyl-nucleotide exchange factor activity protein binding ATP binding intracellular nucleus cytoplasm plasma membrane protein amino acid phosphorylation multicellular organismal development structural constituent of muscle transferase activity myofibril Z disc cell differentiation M band titin binding regulation of Rho protein signal transduction
242396_at	0.270	3.868	2.355	3.233e-02	0.499	-3.667	LOC100132798	similar to hCG1774772	15		AA195408	100132798	15q26.2
201628_s_at	-0.250	9.819	-2.355	3.234e-02	0.499	-3.667	RRAGA	Ras-related GTP binding A	9	19039371	NM_006570	10670	9p22.1	Hs.432330	10	nucleotide binding GTP binding nucleus cytoplasm Golgi apparatus apoptosis cell death virus-host interaction protein homodimerization activity interspecies interaction between organisms positive regulation of cytolysis protein heterodimerization activity phosphoprotein binding
223103_at	0.335	7.374	2.355	3.236e-02	0.499	-3.668	STARD10	StAR-related lipid transfer (START) domain containing 10	11	-72143421	AF151810	10809	11q13	Hs.188606	8
217649_at	-0.264	3.697	-2.355	3.237e-02	0.499	-3.668	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AV702306	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
235619_at	-0.539	8.613	-2.355	3.238e-02	0.499	-3.668	LOC285986	hypothetical protein LOC285986	7		AI681644	285986	7q21.3	Hs.602765	1
211029_x_at	0.275	4.014	2.355	3.238e-02	0.499	-3.668	FGF18	fibroblast growth factor 18	5	170779271	BC006245	8817	5q34	Hs.87191	25	angiogenesis intramembranous ossification endochondral ossification chondrocyte development extracellular region extracellular region extracellular space nucleolus signal transduction cell-cell signaling growth factor activity positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis lung development positive regulation of vascular endothelial growth factor receptor signaling pathway	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
201042_at	0.320	6.969	2.354	3.242e-02	0.499	-3.669	TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	20	-36199764, -36190277	AL031651	7052	20q12	Hs.517033	141	blood vessel remodeling protein-glutamine gamma-glutamyltransferase activity calcium ion binding GTP binding mitochondrion plasma membrane induction of apoptosis acyltransferase activity transferase activity peptide cross-linking isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine protein domain specific binding positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of cell adhesion positive regulation of smooth muscle cell proliferation positive regulation of inflammatory response protein homooligomerization elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	Huntington's disease
208016_s_at	-0.330	5.154	-2.354	3.243e-02	0.499	-3.669	AGTR1	angiotensin II receptor, type 1	3	149898347, 149930656	NM_004835	185	3q21-q25	Hs.477887 Hs.719071	524	regulation of cell growth angiotensin type I receptor activity angiotensin type I receptor activity kidney development renin-angiotensin regulation of aldosterone production regulation of blood vessel size by renin-angiotensin regulation of natriuresis receptor activity G-protein coupled receptor activity angiotensin type II receptor activity plasma membrane integral to plasma membrane oxygen and reactive oxygen species metabolic process signal transduction acetyltransferase activator activity positive regulation of foam cell differentiation positive regulation of cholesterol esterification regulation of vasoconstriction regulation of vasoconstriction regulation of vasoconstriction calcium-mediated signaling bradykinin receptor binding positive regulation of cellular protein metabolic process positive regulation of phospholipase A2 activity positive regulation of NAD(P)H oxidase activity low-density lipoprotein particle remodeling regulation of cell proliferation regulation of vasodilation protein heterodimerization activity positive regulation of inflammatory response elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction Renin-angiotensin system
225627_s_at	-0.280	5.425	-2.354	3.244e-02	0.499	-3.670	CACHD1	cache domain containing 1	1	64709063	AK024256	57685	1p31.3	Hs.708156	4	calcium ion binding ion transport calcium ion transport membrane integral to membrane
205024_s_at	-0.177	4.407	-2.354	3.244e-02	0.499	-3.670	RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	15	38774650	NM_002875	5888	15q15.1	Hs.631709	241	recombinase activity nucleotide binding double-strand break repair via homologous recombination condensed nuclear chromosome damaged DNA binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding ATP binding nucleus nucleus nucleoplasm DNA unwinding during replication DNA repair mitotic recombination response to DNA damage stimulus meiosis reciprocal meiotic recombination protein C-terminus binding PML body ATPase activity identical protein binding single-stranded DNA-dependent ATPase activity positive regulation of DNA ligation protein homooligomerization	Homologous recombination Pathways in cancer Pancreatic cancer
212430_at	-0.487	7.854	-2.352	3.251e-02	0.499	-3.672	RBM38	RNA binding motif protein 38	20	55399869	AL109955	55544	20q13.31	Hs.236361	6	nucleotide binding mRNA 3'-UTR binding nucleus cytoplasm cytosol mRNA processing DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle regulation of RNA splicing protein stabilization
227696_at	0.475	8.541	2.352	3.251e-02	0.499	-3.672	EXOSC6	exosome component 6	16	-68841634	AI701408	118460	16q22.1	Hs.660633 Hs.719211	9	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
232524_x_at	-0.276	6.754	-2.352	3.257e-02	0.499	-3.673	ANAPC4	anaphase promoting complex subunit 4	4	24987945	AK001881	29945	4p15.2	Hs.152173	21	G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
222049_s_at	0.207	3.313	2.351	3.258e-02	0.499	-3.673	RBP4	retinol binding protein 4, plasma	10	-95341582	AA908769	5950	10q23-q24	Hs.50223	110	eye development eye development transporter activity binding extracellular region extracellular space extracellular space gluconeogenesis gluconeogenesis transport visual perception retinal binding retinol binding maintenance of gastrointestinal epithelium lung development positive regulation of insulin secretion response to retinoic acid retinol transporter activity retinol transport retinol metabolic process glucose homeostasis embryonic organ morphogenesis embryonic skeletal system development cardiac muscle tissue development female genitalia morphogenesis response to stimulus positive regulation of immunoglobulin secretion negative regulation of cardiac muscle cell proliferation embryonic retina morphogenesis in camera-type eye uterus development vagina development urinary bladder development heart trabecula formation
52285_f_at	-0.487	3.813	-2.351	3.259e-02	0.499	-3.674	CEP76	centrosomal protein 76kDa	18	-12662630	AW002970	79959	18p11.21	Hs.236940	7	protein binding centriole regulation of centriole replication
202056_at	-0.416	8.604	-2.351	3.260e-02	0.499	-3.674	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	AW051311	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
202313_at	-0.192	8.633	-2.351	3.262e-02	0.499	-3.675	PPP2R2A	protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform	8	26204950	NM_002717	5520	8p21.2	Hs.146339	44	protein phosphatase type 2A complex protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation signal transduction protein phosphatase type 2A regulator activity response to morphine	Tight junction
228086_at	0.303	4.294	2.350	3.264e-02	0.499	-3.675	STK33	serine/threonine kinase 33	11	-8369993	AI703417	65975	11p15.3	Hs.501833	8	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm Golgi apparatus protein amino acid phosphorylation transferase activity perinuclear region of cytoplasm
226957_x_at	-0.322	5.153	-2.350	3.266e-02	0.499	-3.675	RALBP1	ralA binding protein 1	18	9465529	BF433757	10928	18p11.3	Hs.528993 Hs.719181	42	GTPase activator activity protein binding intracellular transport chemotaxis signal transduction small GTPase mediated signal transduction membrane ATPase activity Ral GTPase binding Rac GTPase activator activity regulation of GTPase activity positive regulation of Cdc42 GTPase activity ATPase activity, coupled to movement of substances Rac GTPase binding	Pathways in cancer Pancreatic cancer
1554873_at	-0.211	3.752	-2.350	3.266e-02	0.499	-3.676	CSPP1	centrosome and spindle pole associated protein 1	8	68139156	BC029445	79848	8q13.1-q13.2	Hs.370147	6	centrosome microtubule
217816_s_at	-0.259	9.041	-2.350	3.267e-02	0.499	-3.676	PCNP	PEST proteolytic signal containing nuclear protein	3	102775731	NM_020357	57092	3q12.3	Hs.545311 Hs.654949	6	protein binding nucleus cell cycle protein ubiquitination proteasomal ubiquitin-dependent protein catabolic process
AFFX-HSAC07/X00351_5_at	-0.226	11.188	-2.350	3.267e-02	0.499	-3.676	ACTB	actin, beta	7	-5533304	AFFX-HSAC07/X00351_5	60	7p15-p12	Hs.520640 Hs.708120	206	nucleotide binding structural constituent of cytoskeleton protein binding ATP binding soluble fraction cytoplasm cytosol cell motion cortical cytoskeleton NuA4 histone acetyltransferase complex nitric-oxide synthase binding MLL5-L complex	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
233446_at	0.300	3.362	2.350	3.268e-02	0.499	-3.676	ONECUT2	one cut homeobox 2	18	53253914	AU145336	9480	18q21.1-q21.2	Hs.194725	7	liver development regulation of cell-matrix adhesion epithelial cell development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent organ morphogenesis positive regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway endocrine pancreas development cilium assembly sequence-specific DNA binding cell fate commitment positive regulation of transcription from RNA polymerase II promoter peripheral nervous system neuron development
241816_at	0.226	4.184	2.349	3.270e-02	0.499	-3.677	C14orf106	chromosome 14 open reading frame 106	14	-44742142	AW103300	55320	14q21.2	Hs.437941	10	chromosome, centromeric region DNA binding nucleus cell cycle mitosis cell division
228135_at	-0.320	7.598	-2.349	3.271e-02	0.499	-3.677	C1orf52	chromosome 1 open reading frame 52	1	-85488226	AA738437	148423	1p22.3	Hs.26226	7
210093_s_at	0.250	5.940	2.349	3.272e-02	0.499	-3.677	MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	1	-53465151	AF067173	4116	1p34-p33	Hs.421576	24	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex cytoplasm transport RNA splicing nuclear speck exon-exon junction complex mRNA transport
226164_x_at	0.386	5.187	2.349	3.272e-02	0.499	-3.677	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AI760919	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
1558247_s_at	0.231	3.351	2.349	3.273e-02	0.499	-3.677	NTN5	netrin 5	19	-53856475	BC021210	126147	19q13.33	Hs.326217	1	protein binding extracellular region
206542_s_at	-0.407	8.391	-2.349	3.273e-02	0.499	-3.677	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	AV725365	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
244065_at	-0.455	3.968	-2.349	3.274e-02	0.499	-3.678	LOC643827	similar to cell recognition molecule CASPR3	9		AW016751	643827	9q12
232160_s_at	-0.298	6.866	-2.349	3.274e-02	0.499	-3.678	TNIP2	TNFAIP3 interacting protein 2	4	-2713184, -2713184	AL137262	79155	4p16.3	Hs.719161	20	protein binding cytoplasm I-kappaB kinase/NF-kappaB cascade
219967_at	-0.176	5.597	-2.348	3.276e-02	0.500	-3.678	MRM1	mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)	17	32032137	NM_024864	79922	17q12	Hs.194864	4	RNA binding mitochondrion RNA processing RNA methyltransferase activity transferase activity
227775_at	0.191	3.725	2.348	3.277e-02	0.500	-3.679	BRUNOL6	bruno-like 6, RNA binding protein (Drosophila)	15	-70364121	BE467313	60677	15q24	Hs.348342	5	nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome RNA binding nucleus cytoplasm mRNA processing
225053_at	-0.259	10.293	-2.348	3.278e-02	0.500	-3.679	CNOT7	CCR4-NOT transcription complex, subunit 7	8	-17133392, -17131110	W94952	29883	8p22-p21.3	Hs.645009 Hs.719129	19	nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter	RNA degradation
240479_at	0.287	5.098	2.348	3.281e-02	0.500	-3.679	HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	6	-114483442	AW449310	222537	6q21	Hs.645477	8	protein binding Golgi apparatus protein amino acid sulfation sulfotransferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane integral to membrane transferase activity regulation of virion penetration into host cell 3'-phosphoadenosine 5'-phosphosulfate binding negative regulation of coagulation	Heparan sulfate biosynthesis
231406_at	0.234	5.101	2.348	3.281e-02	0.500	-3.680	ORAI2	ORAI calcium release-activated calcium modulator 2	7	101861000	AW205664	80228	7q22.1	Hs.363308	12	membrane integral to membrane
220862_s_at	0.249	5.447	2.347	3.286e-02	0.500	-3.681	USP22	ubiquitin specific peptidase 22	17	-20843497	NM_014093	23326	17p11.2	Hs.462492	10	SAGA complex ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-specific protease activity protein binding nucleus ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity zinc ion binding embryonic development H4 histone acetyltransferase activity chromatin modification histone ubiquitination histone deubiquitination ligand-dependent nuclear receptor transcription coactivator activity positive regulation of mitotic cell cycle positive regulation of transcription metal ion binding
1555979_at	-0.258	4.398	-2.346	3.290e-02	0.500	-3.682	FLJ39609	similar to hCG1995469	1	-842817	CA447406	100130417	1p36.33	Hs.200644	2
1564972_x_at	-0.203	2.995	-2.346	3.291e-02	0.500	-3.682	SETDB2	SET domain, bifurcated 2	13	48916429, 48923688	AF277186	83852	13q14	Hs.631789 Hs.633823	6	DNA binding nucleus methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity	Lysine degradation
230266_at	0.415	5.235	2.346	3.291e-02	0.500	-3.682	RAB7B	RAB7B, member RAS oncogene family	1		AI127991	338382	1q32	Hs.534612	4	nucleotide binding GTP binding lysosome small GTPase mediated signal transduction protein transport
201962_s_at	-0.419	6.710	-2.346	3.291e-02	0.500	-3.682	RNF41	ring finger protein 41	12	-54884552, -54884552	NM_005785	10193	12q13.2-q13.3	Hs.524502	13	protein binding zinc ion binding protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process protein tag metal ion binding	Endocytosis
213918_s_at	-0.269	5.516	-2.346	3.292e-02	0.500	-3.682	NIPBL	Nipped-B homolog (Drosophila)	5	36912617	BF221673	25836	5p13.2	Hs.481927	22	protein binding nucleus cell cycle cohesin loading complex maintenance of mitotic sister chromatid cohesion
1556567_at	0.232	4.860	2.346	3.293e-02	0.500	-3.683	NAP1L4	nucleosome assembly protein 1-like 4	11	-2922235	BE087543	4676	11p15.5	Hs.501684 Hs.695395	12	nucleus chromatin assembly complex cytoplasm nucleosome assembly unfolded protein binding
219553_at	0.335	6.196	2.346	3.295e-02	0.501	-3.683	NME7	non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)	1	-167368396, -167368392	NM_013330	29922	1q24	Hs.706952	10	nucleotide binding magnesium ion binding nucleoside diphosphate kinase activity ATP binding GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process nucleotide metabolic process kinase activity transferase activity	Purine metabolism Pyrimidine metabolism Metabolic pathways
212447_at	-0.362	8.214	-2.345	3.298e-02	0.501	-3.684	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	7	-32874302	AF161402	25948	7p14.3	Hs.372541	4	protein binding
1555543_a_at	-0.373	5.470	-2.345	3.299e-02	0.501	-3.684	CLCC1	chloride channel CLIC-like 1	1	-109273652	AB052917	23155	1p13.3	Hs.658489	6	nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane
41512_at	-0.396	6.164	-2.345	3.300e-02	0.501	-3.684	BRAP	BRCA1 associated protein	12	-110564332	AL042733	8315	12q24	Hs.530940	12	ubiquitin-protein ligase activity cytoplasm zinc ion binding negative regulation of signal transduction ligase activity modification-dependent protein catabolic process identical protein binding metal ion binding
213523_at	0.221	5.997	2.345	3.301e-02	0.501	-3.685	CCNE1	cyclin E1	19	34994740, 34995400	AI671049	898	19q12	Hs.244723	144	G1/S transition of mitotic cell cycle transcription coactivator activity protein binding nucleus nucleoplasm cytosol cell cycle androgen receptor signaling pathway positive regulation of transcription, DNA-dependent androgen receptor binding cell division	Cell cycle p53 signaling pathway Pathways in cancer Prostate cancer Small cell lung cancer
211672_s_at	-0.352	6.332	-2.345	3.301e-02	0.501	-3.685	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	3	9809226	AF019888	10093	3p25.3	Hs.323342	16	cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
206024_at	0.246	3.309	2.344	3.305e-02	0.501	-3.686	HPD	4-hydroxyphenylpyruvate dioxygenase	12	-120761815	NM_002150	3242	12q24-qter	Hs.2899	11	4-hydroxyphenylpyruvate dioxygenase activity iron ion binding endoplasmic reticulum Golgi apparatus L-phenylalanine catabolic process tyrosine catabolic process aromatic amino acid family metabolic process oxidoreductase activity metal ion binding oxidation reduction	Ubiquinone and other terpenoid-quinone biosynthesis Tyrosine metabolism Phenylalanine metabolism Metabolic pathways
238722_x_at	0.295	5.906	2.343	3.314e-02	0.502	-3.688	NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D	7	-102527258	AI460037	222236	7q22.1	Hs.324271	5	lipid metabolic process zinc ion binding phospholipid catabolic process membrane hydrolase activity metal ion binding
1569332_at	-0.243	2.853	-2.342	3.317e-02	0.502	-3.689	C3orf66	chromosome 3 open reading frame 66	3	110379701	BC022563	677779	3q13.13	Hs.618669	2
1553959_a_at	0.284	6.229	2.342	3.320e-02	0.502	-3.690	B3GALT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6	1	1157491	N95564	126792	1p36.33	Hs.284284	4	Golgi apparatus Golgi medial cisterna glycosaminoglycan biosynthetic process protein amino acid glycosylation UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding galactosylxylosylprotein 3-beta-galactosyltransferase activity	Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways
1560002_at	-0.358	4.124	-2.341	3.322e-02	0.502	-3.690	LOC100132859	similar to Protein FAM27D1	9		BI917658	100132859	9q13
205521_at	0.372	5.928	2.341	3.322e-02	0.502	-3.690	EXOG	endo/exonuclease (5'-3'), endonuclease G-like	3	38512766	BF511976	9941	3p21.3	Hs.517897	6	nucleic acid binding endonuclease activity cellular_component mitochondrion mitochondrial inner membrane biological_process membrane hydrolase activity metal ion binding	Apoptosis
227176_at	-0.256	5.049	-2.341	3.323e-02	0.502	-3.690	SLC2A13	solute carrier family 2 (facilitated glucose transporter), member 13	12	-38435091	AL565362	114134	12q12	Hs.558595	5	transporter activity membrane integral to membrane substrate-specific transmembrane transporter activity transmembrane transport
221875_x_at	0.353	8.396	2.341	3.324e-02	0.502	-3.691	HLA-F	major histocompatibility complex, class I, F	6	29799095, 29799095, 1143812, 1143812, 945922, 945922	AW514210	3134	6p21.3	Hs.519972	68	antigen processing and presentation of peptide antigen via MHC class I immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
229245_at	0.336	4.256	2.341	3.324e-02	0.502	-3.691	PLEKHA6	pleckstrin homology domain containing, family A member 6	1	-202454603	AA535361	22874	1q32.1	Hs.253146	9
229378_at	0.198	3.502	2.341	3.325e-02	0.502	-3.691	STOX1	storkhead box 1	10	70257299, 70257299, 70257568	N53051	219736	10q21.3-q22.1	Hs.37636	9	DNA binding nucleus nucleolus cytoplasm
203540_at	0.254	3.306	2.341	3.325e-02	0.502	-3.691	GFAP	glial fibrillary acidic protein	17	-40342566, -40338518	NM_002055	2670	17q21	Hs.514227	110	structural constituent of cytoskeleton protein binding cytoplasm intermediate filament
41644_at	0.300	7.141	2.341	3.326e-02	0.502	-3.691	SASH1	SAM and SH3 domain containing 1	6	148705421	AB018333	23328	6q24.3	Hs.193133	12	protein binding
209364_at	-0.203	7.108	-2.341	3.328e-02	0.502	-3.692	BAD	BCL2-associated agonist of cell death	11	-63793876	U66879	572	11q13.1	Hs.370254	130	protein binding protein binding cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane cytosol induction of apoptosis activation of pro-apoptotic gene products membrane	ErbB signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Neurotrophin signaling pathway Insulin signaling pathway Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Pancreatic cancer Endometrial cancer Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
238635_at	0.215	2.314	2.340	3.334e-02	0.503	-3.693	C5orf28	chromosome 5 open reading frame 28	5	-43480110	W72333	64417	5p12	Hs.558531	5	membrane integral to membrane
36830_at	-0.426	6.161	-2.339	3.334e-02	0.503	-3.694	MIPEP	mitochondrial intermediate peptidase	13	-23202327	U80034	4285	13q12	Hs.507498	6	magnesium ion binding metalloendopeptidase activity iron ion binding calcium ion binding mitochondrion mitochondrial matrix proteolysis mitochondrial protein processing during import peptidase activity zinc ion binding manganese ion binding cobalt ion binding
221215_s_at	0.206	5.756	2.339	3.337e-02	0.503	-3.694	RIPK4	receptor-interacting serine-threonine kinase 4	21	-42032597	NM_020639	54101	21q22.3	Hs.517310	13	nucleotide binding protein serine/threonine kinase activity receptor activity ATP binding cytoplasm protein amino acid phosphorylation membrane transferase activity
1569867_at	0.213	4.098	2.339	3.337e-02	0.503	-3.694	EME2	essential meiotic endonuclease 1 homolog 2 (S. pombe)	16	1763229	BC041011	197342	16p13.3	Hs.7247	4	DNA binding endonuclease activity protein binding nucleus DNA repair DNA recombination response to DNA damage stimulus hydrolase activity
227239_at	-0.533	8.467	-2.339	3.340e-02	0.503	-3.695	FAM126A	family with sequence similarity 126, member A	7	-22947402	AV734839	84668	7p15.3	Hs.85603	9	signal transducer activity cellular_component cytoplasm biological_process membrane
213444_at	0.244	5.652	2.338	3.343e-02	0.503	-3.696	ZNF862	zinc finger protein 862	7	149166441	AB011115	643641	7q36.1	Hs.301277	4	nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding protein dimerization activity
219868_s_at	-0.175	4.908	-2.338	3.343e-02	0.503	-3.696	ANKFY1	ankyrin repeat and FYVE domain containing 1	17	-4044521, -4013413	NM_016376	51479	17p13.3	Hs.696087	11	protein binding cytoplasm endosome zinc ion binding endosome membrane membrane metal ion binding
218554_s_at	-0.220	5.132	-2.337	3.348e-02	0.504	-3.697	ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)	1	-153571675	NM_018489	55870	1q22	Hs.491060	10	DNA binding RNA polymerase II transcription factor activity protein binding nucleus tight junction DNA packaging transcription from RNA polymerase II promoter cell-cell signaling methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity cell junction regulation of transcription metal ion binding	Lysine degradation Tight junction
223518_at	0.210	5.792	2.337	3.354e-02	0.505	-3.698	DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	1	-10443189	AF087573	1676	1p36.3-p36.2	Hs.484782	44	caspase-activated deoxyribonuclease activity intracellular nucleus nucleoplasm cytoplasm cytosol DNA fragmentation involved in apoptosis intracellular signaling cascade identical protein binding negative regulation of apoptosis	Apoptosis
228937_at	0.688	3.778	2.335	3.365e-02	0.506	-3.702	C13orf31	chromosome 13 open reading frame 31	13	43351419, 43351968	AI659800	144811	13q14.11	Hs.210586	5
206356_s_at	-0.446	5.119	-2.335	3.366e-02	0.506	-3.702	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18	11679135, 11741561	NM_002071	2774	18p11.22-p11.21	Hs.136295	16	nucleotide binding GTPase activity signal transducer activity GTP binding signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding	Calcium signaling pathway Olfactory transduction
224719_s_at	0.314	9.100	2.335	3.367e-02	0.506	-3.702	C12orf57	chromosome 12 open reading frame 57	12	6923463	BG339653	113246	12p13.31	Hs.405913 Hs.591045	5
219600_s_at	-0.588	6.912	-2.334	3.370e-02	0.506	-3.703	TMEM50B	transmembrane protein 50B	21	-33743317	NM_006134	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
226597_at	-0.315	4.171	-2.334	3.371e-02	0.506	-3.703	REEP6	receptor accessory protein 6	19	1442164	AI348159	92840	19p13.3	Hs.76277	6	membrane integral to membrane
232523_at	-0.694	6.578	-2.334	3.371e-02	0.506	-3.703	MEGF10	multiple EGF-like-domains 10	5	126654354	AU144892	84466	5q33	Hs.438709	9	protein binding plasma membrane phagocytosis cell adhesion integral to membrane
204285_s_at	-0.458	4.893	-2.334	3.373e-02	0.506	-3.703	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	18	55718171	AI857639	5366	18q21.32	Hs.96	36	release of cytochrome c from mitochondria protein binding mitochondrion induction of apoptosis activation of caspase activity cell structure disassembly during apoptosis virus-infected cell apoptosis response to dsRNA	p53 signaling pathway
1556113_at	-0.218	5.615	-2.333	3.374e-02	0.506	-3.704	DKFZp451A211	DKFZp451A211 protein	13		BC036906	400169	13q34	Hs.646609	1
214006_s_at	0.228	6.676	2.333	3.376e-02	0.506	-3.704	GGCX	gamma-glutamyl carboxylase	2	-85629703	BE326952	2677	2p12	Hs.77719	53	membrane fraction endoplasmic reticulum protein modification process blood coagulation gamma-glutamyl carboxylase activity membrane integral to membrane ligase activity peptidyl-glutamic acid carboxylation
229730_at	-0.498	9.352	-2.333	3.377e-02	0.506	-3.705	SMTNL2	smoothelin-like 2	17	4434024, 4434582	AI193973	342527	17p13.2	Hs.441709	2
209797_at	0.247	7.507	2.333	3.377e-02	0.506	-3.705	CNPY2	canopy 2 homolog (zebrafish)	12	-54990483	BC001027	10330	12q15	Hs.8752	7	protein binding endoplasmic reticulum integral to plasma membrane
210296_s_at	-0.294	8.183	-2.333	3.379e-02	0.506	-3.705	PXMP3	peroxisomal membrane protein 3, 35kDa	8	-78055048	BC005375	5828	8q21.1	Hs.437966 Hs.703022	19	neuron migration protein binding peroxisome peroxisomal membrane integral to peroxisomal membrane peroxisome organization nervous system development zinc ion binding membrane integral to membrane metal ion binding
210837_s_at	-0.259	2.675	-2.333	3.380e-02	0.506	-3.705	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	AF012074	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
215424_s_at	-0.387	7.230	-2.333	3.380e-02	0.506	-3.705	SNW1	SNW domain containing 1	14	-77253696	AV689564	22938	14q24.3	Hs.445498	32	nuclear mRNA splicing, via spliceosome transcription coactivator activity Notch binding protein binding nucleus spliceosomal complex nucleolus regulation of transcription from RNA polymerase II promoter RNA splicing negative regulation of transcription	Notch signaling pathway
202212_at	-0.170	6.664	-2.332	3.381e-02	0.506	-3.705	PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)	22	-29302611	NM_014303	23481	22q12.1	Hs.517543	20	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding intracellular nucleus nucleoplasm nucleolus rRNA processing cell proliferation cell proliferation preribosome, large subunit precursor ribosomal large subunit biogenesis regulation of cell cycle PeBoW complex
207108_s_at	-0.221	4.947	-2.332	3.384e-02	0.506	-3.706	NIPBL	Nipped-B homolog (Drosophila)	5	36912617	NM_015384	25836	5p13.2	Hs.481927	22	protein binding nucleus cell cycle cohesin loading complex maintenance of mitotic sister chromatid cohesion
221324_at	0.248	4.409	2.332	3.384e-02	0.506	-3.706	TAS2R1	taste receptor, type 2, member 1	5	-9682108	NM_019599	50834	5p15	Hs.567492	12	receptor activity signal transduction G-protein coupled receptor protein signaling pathway chemosensory behavior taste receptor activity membrane integral to membrane response to stimulus sensory perception of taste	Taste transduction
207817_at	-0.216	3.208	-2.332	3.384e-02	0.506	-3.706	IFNW1	interferon, omega 1	9	-21130630	NM_002177	3467	9p22	Hs.73010	14	cytokine activity cytokine receptor binding extracellular region extracellular space defense response cell cycle arrest response to virus	Cytokine-cytokine receptor interaction RIG-I-like receptor signaling pathway Jak-STAT signaling pathway
1559060_a_at	-0.466	5.104	-2.332	3.386e-02	0.506	-3.707	FNIP1	folliculin interacting protein 1	5	-131005305	BF677986	96459	5q23.3	Hs.591273	4	cytoplasm
224726_at	0.233	7.604	2.332	3.386e-02	0.506	-3.707	MIB1	mindbomb homolog 1 (Drosophila)	18	17575542	W80418	57534	18q11.2	Hs.140903 Hs.658808	15	blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding
230136_at	0.498	5.281	2.332	3.387e-02	0.506	-3.707	LOC400099	hypothetical LOC400099	13		AI573252	400099	13q12.11	Hs.400432
221954_at	-0.387	7.321	-2.331	3.389e-02	0.506	-3.708	C20orf111	chromosome 20 open reading frame 111	20	-42258549	AA160474	51526	20q13.11	Hs.75798	6
225376_at	0.192	6.726	2.331	3.391e-02	0.506	-3.708	C20orf11	chromosome 20 open reading frame 11	20	61039885	BG480592	54994	20q13.33	Hs.353013	7	protein binding nucleus
201662_s_at	-0.404	7.577	-2.331	3.392e-02	0.506	-3.708	ACSL3	acyl-CoA synthetase long-chain family member 3	2	223433975	D89053	2181	2q34-q35	Hs.655772	20	nucleotide binding magnesium ion binding fatty-acyl-CoA synthase activity long-chain-fatty-acid-CoA ligase activity protein binding ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
217286_s_at	0.212	7.975	2.330	3.394e-02	0.507	-3.709	NDRG3	NDRG family member 3	20	-34713582	BC001805	57446	20q11.21-q11.23	Hs.437338	9	molecular_function cytoplasm spermatogenesis cell differentiation negative regulation of cell growth
224318_s_at	-0.354	8.751	-2.330	3.395e-02	0.507	-3.709	KIAA1310	KIAA1310	2	-96622633	AF311326	55683	2p12-p11.2	Hs.516341	10
222439_s_at	-0.438	7.555	-2.330	3.397e-02	0.507	-3.710	THRAP3	thyroid hormone receptor associated protein 3	1	36462603	BE967048	9967	1p34.3	Hs.160211	21	nucleotide binding receptor activity protein binding ATP binding nucleus nucleolus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
231966_at	-0.239	4.126	-2.330	3.400e-02	0.507	-3.710	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A	7	94374884	AB033048	55607	7q21.3	Hs.21816	12	actin binding protein binding cytoplasm cytoskeleton actin filament organization multicellular organismal development nervous system development synaptosome cell junction cell differentiation filopodium cortical actin cytoskeleton dendritic spine synapse
221629_x_at	0.237	6.634	2.329	3.402e-02	0.507	-3.711	C8orf30A	chromosome 8 open reading frame 30A	8	145264659, 145408687	AF151022	51236	8q24.3	Hs.300224	5	binding cellular_component biological_process
216682_s_at	0.205	3.200	2.329	3.403e-02	0.507	-3.711	FAM48A	family with sequence similarity 48, member A	13	-36481450	AK021457	55578	13q13.3	Hs.435815	14	protein binding multicellular organismal development gastrulation
221255_s_at	0.187	9.635	2.329	3.404e-02	0.507	-3.712	TMEM93	transmembrane protein 93	17	3518838	NM_031298	83460	17p13.2	Hs.30011	3	membrane integral to membrane
209177_at	0.272	8.781	2.329	3.405e-02	0.507	-3.712	NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3	3	49032911, 49033621, 49034077	BC002873	25915	3p21.31	Hs.31387	8	protein binding nucleus mitochondrial inner membrane mitochondrial respiratory chain complex I assembly
220603_s_at	0.219	2.871	2.329	3.406e-02	0.507	-3.712	MCTP2	multiple C2 domains, transmembrane 2	15	92642433, 92700167	NM_018349	55784	15q26.2	Hs.33368 Hs.592017	7	calcium ion binding calcium-dependent phospholipid binding membrane fraction membrane integral to membrane calcium-mediated signaling
212796_s_at	0.241	6.174	2.328	3.407e-02	0.507	-3.712	TBC1D2B	TBC1 domain family, member 2B	15	-76074381	BF195608	23102	15q24.3-q25.1	Hs.719242	2	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
236321_at	0.312	5.266	2.328	3.407e-02	0.507	-3.712	LOC285550	hypothetical protein LOC285550	4	15292449	AW439843	285550	4p15.32	Hs.399980 Hs.619367	3
212333_at	-0.295	8.992	-2.328	3.412e-02	0.507	-3.713	FAM98A	family with sequence similarity 98, member A	2	-33662232	AL049943	25940	2p22.3	Hs.468140	2
211251_x_at	-0.183	7.421	-2.327	3.414e-02	0.507	-3.714	NFYC	nuclear transcription factor Y, gamma	1	40929828, 40930266	U78774	4802	1p32	Hs.233458 Hs.713051	24	transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding intracellular nucleus regulation of transcription from RNA polymerase II promoter protein folding CCAAT-binding factor complex sequence-specific DNA binding	Antigen processing and presentation
222550_at	-0.230	8.687	-2.327	3.415e-02	0.507	-3.714	ARMC1	armadillo repeat containing 1	8	-66677627	AK024053	55156	8q13.1	Hs.269542	3	binding metal ion transport metal ion binding
210122_at	-0.220	3.382	-2.327	3.415e-02	0.507	-3.714	PRM2	protamine 2	16	-11276993	BC005303	5620	16p13.2	Hs.2324	36	nucleosome DNA binding nucleus nucleoplasm chromosome nucleus organization multicellular organismal development spermatogenesis spermatid development cell differentiation chromosome condensation
238825_at	0.384	5.205	2.327	3.417e-02	0.507	-3.715	ACRC	acidic repeat containing	X	70714598	AI091533	93953	Xq13.1	Hs.135167	3	nucleus
222279_at	0.243	4.999	2.327	3.418e-02	0.507	-3.715	RP3-377H14.5	hypothetical LOC285830	6	-29802356, -1147069, -949185	AI669379	285830	6p22.1	Hs.646985	2
228214_at	-0.486	7.401	-2.327	3.418e-02	0.507	-3.715	SOX6	SRY (sex determining region Y)-box 6	11	-15944571, -15944571, -15944571	AW242286	55553	11p15.3	Hs.368226	24	transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent multicellular organismal development muscle organ development
1565660_at	0.269	5.656	2.326	3.420e-02	0.507	-3.716	FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	19	-5781636	BC040472	2528	19p13.3	Hs.631846 Hs.705615	19	Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
227892_at	0.576	9.418	2.326	3.420e-02	0.507	-3.716	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	AA855042	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
201631_s_at	-0.379	6.178	-2.326	3.422e-02	0.507	-3.716	IER3	immediate early response 3	6	-30818954, -2159551, -1957851	NM_003897	8870	6p21.3	Hs.591785	37	protein binding apoptosis anti-apoptosis anatomical structure morphogenesis membrane integral to membrane
213389_at	-0.275	6.844	-2.326	3.422e-02	0.507	-3.716	ZNF592	zinc finger protein 592	15	83092821	BF508616	9640	15q25.3	Hs.79347	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212833_at	-0.354	8.755	-2.326	3.424e-02	0.507	-3.716	SLC25A46	solute carrier family 25, member 46	5	110102652	M74089	91137	5q22.1	Hs.75639	5	binding cellular_component mitochondrion mitochondrial inner membrane transport biological_process membrane integral to membrane
1560276_at	0.463	7.318	2.326	3.424e-02	0.507	-3.716	LOC283403	hypothetical protein LOC283403	12		BC038743	283403	12q13.13	Hs.667179	1
207251_at	-0.212	3.440	-2.326	3.425e-02	0.507	-3.717	MEP1B	meprin A, beta	18	28023984	NM_005925	4225	18q12.2-q12.3	Hs.194777	18	metalloendopeptidase activity extracellular space membrane fraction plasma membrane integral to plasma membrane proteolysis digestion peptidase activity zinc ion binding metal ion binding
205315_s_at	0.346	6.611	2.325	3.427e-02	0.508	-3.717	SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	16	67778550	NM_006750	6645	16q22-q23	Hs.461117	22	actin binding calcium ion binding calmodulin binding membrane fraction cytoplasm cytoskeleton microtubule dystrophin-associated glycoprotein complex membrane cell junction cytoplasmic vesicle synapse
227944_at	0.367	6.249	2.325	3.431e-02	0.508	-3.718	PTPN3	protein tyrosine phosphatase, non-receptor type 3	9	-111177794, -111177794, -111177794, -111177794	BF437260	5774	9q31	Hs.436429	20	protein tyrosine phosphatase activity cytoplasm cytoskeleton plasma membrane protein amino acid dephosphorylation cytoskeletal protein binding hydrolase activity extrinsic to membrane negative regulation of membrane protein ectodomain proteolysis
213056_at	0.302	3.725	2.325	3.432e-02	0.508	-3.718	FRMD4B	FERM domain containing 4B	3	-69301835	AU145019	23150	3p14.1	Hs.709671	5	binding cytoplasm cytoskeleton
236436_at	-0.344	5.710	-2.325	3.432e-02	0.508	-3.718	SLC25A45	solute carrier family 25, member 45	11	-64899238	AI336233	283130	11q13.1	Hs.661604	4	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
233409_at	0.182	5.523	2.325	3.432e-02	0.508	-3.718	RHBDL3	rhomboid, veinlet-like 3 (Drosophila)	17	27617307	AL133573	162494	17q11.2	Hs.655027	3	serine-type endopeptidase activity calcium ion binding signal transduction peptidase activity membrane integral to membrane
212388_at	-0.489	7.751	-2.324	3.435e-02	0.508	-3.719	USP24	ubiquitin specific peptidase 24	1	-55304619	AB028980	23358	1p32.3	Hs.477009	13	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
213588_x_at	-0.196	12.014	-2.324	3.435e-02	0.508	-3.719	RPL14	ribosomal protein L14	3	40473804, 40473833	AA838274	9045	3p22-p21.2	Hs.719095	21	RNA binding structural constituent of ribosome protein binding intracellular cytoplasm cytosol ribosome rRNA processing translational elongation cytosolic large ribosomal subunit ribosomal large subunit biogenesis	Ribosome
242176_at	-0.235	5.443	-2.324	3.436e-02	0.508	-3.720	MEF2A	myocyte enhancer factor 2A	15	97923655, 97990705	AA491228	4205	15q26	Hs.268675	77	transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding
206580_s_at	0.285	6.882	2.324	3.437e-02	0.508	-3.720	EFEMP2	EGF-containing fibulin-like extracellular matrix protein 2	11	-65390487	NM_016938	30008	11q13.1	Hs.170622	15	transmembrane receptor activity extracellular matrix structural constituent calcium ion binding protein binding extracellular region basement membrane blood coagulation membrane
208057_s_at	-0.193	6.365	-2.324	3.437e-02	0.508	-3.720	GLI2	GLI family zinc finger 2	2	121271336	D14827	2736	2q14	Hs.111867	35	negative regulation of transcription from RNA polymerase II promoter skeletal system development kidney development osteoblast development transcription factor activity intracellular nucleus smoothened signaling pathway pattern specification process axon guidance hindgut morphogenesis heart development zinc ion binding cell proliferation proximal/distal pattern formation transcription activator activity floor plate formation spinal cord dorsal/ventral patterning ventral spinal cord development cerebellar cortex morphogenesis smoothened signaling pathway involved in ventral spinal cord interneuron specification spinal cord ventral commissure morphogenesis pituitary gland development lung development mammary gland development hindbrain development notochord development tube development odontogenesis of dentine-containing tooth sequence-specific DNA binding regulation of transcription positive regulation of DNA replication positive regulation of transcription from RNA polymerase II promoter metal ion binding embryonic gut development developmental growth neuron development branching morphogenesis of a tube	Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma
223743_s_at	0.427	7.087	2.323	3.440e-02	0.508	-3.721	MRPL4	mitochondrial ribosomal protein L4	19	10223639, 10223639	BC000756	51073	19p13.2	Hs.279652	10	structural constituent of ribosome intracellular mitochondrion ribosome translation
212124_at	0.331	7.734	2.323	3.441e-02	0.508	-3.721	ZMIZ1	zinc finger, MIZ-type containing 1	10	80498797	AF070622	57178	10q22.3	Hs.193118	14	vasculogenesis in utero embryonic development heart morphogenesis protein binding nucleus cytoplasm vitellogenesis cell aging zinc ion binding nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding positive regulation of fibroblast proliferation developmental growth artery morphogenesis
224053_s_at	-0.201	5.403	-2.323	3.446e-02	0.508	-3.722	SLC4A9	solute carrier family 4, sodium bicarbonate cotransporter, member 9	5	139719970	AF336237	83697	5q31	Hs.550313	3	transporter activity inorganic anion exchanger activity anion transport anion transmembrane transporter activity antiporter activity membrane integral to membrane apical part of cell
216347_s_at	0.214	6.265	2.322	3.447e-02	0.508	-3.722	PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	14	-103269840	AK023188	23368	14q32.33	Hs.709297	13	protein binding nucleus cytoplasm apoptosis induction of apoptosis negative regulation of cell cycle
206188_at	0.242	4.039	2.322	3.451e-02	0.508	-3.723	ZNF623	zinc finger protein 623	8	144789515, 144803096	NM_014789	9831	8q24.3	Hs.43133 Hs.694018	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
202539_s_at	-0.372	5.336	-2.321	3.453e-02	0.508	-3.724	HMGCR	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	5	74668748	AL518627	3156	5q13.3-q14	Hs.643495 Hs.698445 Hs.713530	72	hydroxymethylglutaryl-CoA reductase (NADPH) activity peroxisome endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane cholesterol biosynthetic process isoprenoid biosynthetic process germ cell migration gonad development coenzyme A metabolic process membrane integral to membrane oxidoreductase activity NADP or NADPH binding oxidation reduction	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
215978_x_at	0.233	9.064	2.321	3.454e-02	0.508	-3.724	LOC152719	hypothetical protein LOC152719	4		AK021514	152719	4p16.3	Hs.428360	1
217405_x_at	0.267	3.967	2.321	3.457e-02	0.508	-3.725	GPLD1	glycosylphosphatidylinositol specific phospholipase D1	6	-24581304, -24536383	AL031230	2822	6p22.3-p22.2	Hs.533291	26	glycosylphosphatidylinositol phospholipase D activity extracellular region hydrolase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
211323_s_at	0.334	4.727	2.321	3.458e-02	0.508	-3.725	ITPR1	inositol 1,4,5-triphosphate receptor, type 1	3	4510033	L38019	3708	3p26-p25	Hs.567295 Hs.715765	87	response to hypoxia ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium channel activity calcium ion binding protein binding endoplasmic reticulum ion transport calcium ion transport signal transduction cell death calcium ion transmembrane transporter activity membrane integral to membrane platelet dense granule membrane platelet dense tubular network membrane	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease Huntington's disease
203390_s_at	0.292	4.767	2.320	3.462e-02	0.508	-3.726	KIF3C	kinesin family member 3C	2	-26002958	NM_002254	3797	2p23	Hs.21611	9	nucleotide binding microtubule motor activity ATP binding kinesin complex microtubule microtubule-based movement
218987_at	0.376	6.961	2.320	3.462e-02	0.508	-3.726	ATF7IP	activating transcription factor 7 interacting protein	12	14409877	NM_018179	55729	12p13.1	Hs.714407	17	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding nucleus transcription factor complex cytoplasm DNA methylation ATPase activity interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent regulation of transcriptional preinitiation complex assembly
228622_s_at	0.245	7.183	2.320	3.462e-02	0.508	-3.726	DNAJC4	DnaJ (Hsp40) homolog, subfamily C, member 4	11	63754328	AW071239	3338	11q13	Hs.172847	4	membrane fraction protein folding response to unfolded protein membrane integral to membrane heat shock protein binding unfolded protein binding
203400_s_at	0.238	3.055	2.320	3.463e-02	0.508	-3.726	TF	transferrin	3	134947924	NM_001063	7018	3q22.1	Hs.518267	163	response to hypoxia protein binding extracellular region basement membrane extracellular space early endosome late endosome ion transport cellular iron ion homeostasis acute-phase response ferric iron binding basal plasma membrane response to organic cyclic substance ferric iron transmembrane transporter activity ferric iron transport endocytic vesicle positive regulation of myelination metal ion binding perinuclear region of cytoplasm recycling endosome
212969_x_at	0.248	5.102	2.320	3.463e-02	0.508	-3.726	EML3	echinoderm microtubule associated protein like 3	11	-62126266	BE222618	256364	11q12.3	Hs.379785	8	protein binding cytoplasm microtubule
200912_s_at	-0.223	12.291	-2.320	3.463e-02	0.508	-3.726	EIF4A2	eukaryotic translation initiation factor 4A, isoform 2	3	187984054	NM_001967	1974	3q28	Hs.518475 Hs.599481	15	nucleotide binding RNA binding translation initiation factor activity helicase activity protein binding ATP binding cytosol translation regulation of translational initiation ATP-dependent helicase activity eukaryotic translation initiation factor 4F complex hydrolase activity interspecies interaction between organisms
232686_at	0.285	3.515	2.320	3.463e-02	0.508	-3.726	SIGLECP3	sialic acid binding Ig-like lectin, pseudogene 3	19	56362396	AI801574	284367	19q13.3	Hs.132045	3
225268_at	-0.347	10.637	-2.320	3.464e-02	0.508	-3.727	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	AU144710	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
1554396_at	0.268	5.094	2.320	3.464e-02	0.508	-3.727	UEVLD	UEV and lactate/malate dehyrogenase domains	11	-18509819	BC011011	55293	11p15.1	Hs.407991	5	binding glycolysis metabolic process protein transport oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor small conjugating protein ligase activity modification-dependent protein catabolic process post-translational protein modification cellular carbohydrate metabolic process regulation of protein metabolic process
227220_at	0.240	5.103	2.320	3.465e-02	0.508	-3.727	NFXL1	nuclear transcription factor, X-box binding-like 1	4	-47544013	AI743731	152518	4p12	Hs.646325	6	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding membrane integral to membrane metal ion binding
244345_at	0.207	2.913	2.320	3.467e-02	0.508	-3.727	CADM1	cell adhesion molecule 1	11	-114549554	AI627453	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
229577_at	0.225	5.122	2.319	3.469e-02	0.508	-3.728	AGPAT6	1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)	8	41554863	AI742085	137964	8p11.21	Hs.355753	7	glandular epithelial cell maturation 1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity membrane fraction endoplasmic reticulum endoplasmic reticulum acyl-CoA metabolic process phosphatidylcholine biosynthetic process lactation metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process triglyceride biosynthetic process regulation of multicellular organism growth diacylglycerol metabolic process	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways
213851_at	-0.558	7.019	-2.319	3.469e-02	0.508	-3.728	TMEM110	transmembrane protein 110	3	-52848937	BG031677	375346	3p21.1	Hs.705605	2	molecular_function cellular_component biological_process membrane integral to membrane
228810_at	-0.361	5.632	-2.319	3.471e-02	0.509	-3.728	CCNYL1	cyclin Y-like 1	2	208284508	AW135279	151195	2q33.3	Hs.471234 Hs.597952	5
203387_s_at	-0.487	8.548	-2.318	3.476e-02	0.509	-3.730	TBC1D4	TBC1 domain family, member 4	13	-74756809	NM_014832	9882	13q22.2	Hs.210891	26	GTPase activator activity Rab GTPase activator activity intracellular cytoplasm regulation of Rab GTPase activity
202098_s_at	0.260	6.417	2.318	3.477e-02	0.509	-3.730	PRMT2	protein arginine methyltransferase 2	21	46879954	NM_001535	3275	21q22.3	Hs.154163	17	signal transducer activity nucleus protein amino acid methylation signal transduction methyltransferase activity transferase activity identical protein binding
200761_s_at	-0.304	10.622	-2.318	3.478e-02	0.509	-3.730	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	3	69216779	NM_006407	10550	3p14	Hs.518060 Hs.716493	30	protein binding cytoplasm endoplasmic reticulum L-glutamate transport membrane integral to membrane
36711_at	-2.468	5.879	-2.318	3.479e-02	0.509	-3.730	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	22	36927884, 36928972	AL021977	23764	22q13.1	Hs.517617	14	in utero embryonic development transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress parturition sequence-specific DNA binding regulation of epidermal cell differentiation
232087_at	0.274	4.906	2.318	3.479e-02	0.509	-3.730	CXorf23	chromosome X open reading frame 23	X	-19844038	AW628045	256643	Xp22.12	Hs.28896	2	mitochondrion
231781_s_at	-0.582	9.640	-2.317	3.484e-02	0.509	-3.731	LRRC2	leucine rich repeat containing 2	3	-46531881, -46531881	AK021919	79442	3p21.31	Hs.657345	7	protein binding
209106_at	-0.302	7.862	-2.317	3.485e-02	0.509	-3.732	NCOA1	nuclear receptor coactivator 1	2	24660849	BF576458	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
205760_s_at	0.217	5.928	2.317	3.485e-02	0.509	-3.732	OGG1	8-oxoguanine DNA glycosylase	3	9766627, 9766627	NM_016821	4968	3p26.2	Hs.380271	243	damaged DNA binding endonuclease activity protein binding nucleus nucleoplasm nucleoplasm mitochondrion base-excision repair nucleotide-excision repair response to DNA damage stimulus metabolic process oxidized purine base lesion DNA N-glycosylase activity oxidized purine base lesion DNA N-glycosylase activity hydrolase activity, acting on glycosyl bonds lyase activity depurination	Base excision repair
219620_x_at	-0.318	5.497	-2.317	3.487e-02	0.509	-3.732	C9orf167	chromosome 9 open reading frame 167	9	139292100	NM_017723	54863	9q34.3	Hs.495541	1	nucleotide binding ATP binding endoplasmic reticulum membrane integral to membrane nucleoside-triphosphatase activity chaperone mediated protein folding requiring cofactor
212111_at	-0.245	6.915	-2.316	3.490e-02	0.510	-3.733	STX12	syntaxin 12	1	27972280	AA628051	23673	1p35-p34.1	Hs.523855	18	SNAP receptor activity Golgi apparatus intracellular protein transport membrane integral to membrane vesicle-mediated transport cholesterol efflux membrane raft phagocytic vesicle protein stabilization	SNARE interactions in vesicular transport
201503_at	-0.381	9.351	-2.316	3.491e-02	0.510	-3.733	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	BG500067	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
221497_x_at	-0.392	7.147	-2.315	3.498e-02	0.510	-3.735	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	BC005369	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
204747_at	-0.250	6.255	-2.315	3.498e-02	0.510	-3.735	IFIT3	interferon-induced protein with tetratricopeptide repeats 3	10	91077581, 91082218	NM_001549	3437	10q24	Hs.714337	14	binding cellular_component biological_process
226908_at	0.237	2.841	2.315	3.499e-02	0.510	-3.735	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	12	-57552204, -57552203	AI627704	121227	12q14.1	Hs.715683	9	protein binding membrane integral to membrane
1559399_s_at	0.460	4.963	2.315	3.499e-02	0.510	-3.735	ZCCHC10	zinc finger, CCHC domain containing 10	5	-132360575	BC015986	54819	5q31.1	Hs.29700	5	nucleic acid binding zinc ion binding metal ion binding
223380_s_at	-0.374	7.621	-2.314	3.506e-02	0.510	-3.737	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	13	-20445175	AF207547	26524	13q11-q12	Hs.78960	17	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding spindle pole protein serine/threonine kinase activity ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation cell cycle mitosis protein kinase cascade hormone-mediated signaling transferase activity negative regulation of cyclin-dependent protein kinase activity cell division
243027_at	0.229	2.633	2.313	3.508e-02	0.510	-3.737	IGSF5	immunoglobulin superfamily, member 5	21	40039203	AI824021	150084	21q22.2	Hs.422120	3	plasma membrane tight junction integral to membrane cell junction	Tight junction Epithelial cell signaling in Helicobacter pylori infection
212487_at	0.322	7.068	2.313	3.508e-02	0.510	-3.737	GPATCH8	G patch domain containing 8	17	-39828175	AI673812	23131	17q21.31	Hs.463129	8	molecular_function cellular_component biological_process
220907_at	-0.153	4.761	-2.313	3.508e-02	0.510	-3.737	GPR110	G protein-coupled receptor 110	6	-47095580, -47075771	NM_025048	266977	6p12.3	Hs.256897	11	G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
227627_at	0.192	6.360	2.313	3.512e-02	0.511	-3.738	SGK3	serum/glucocorticoid regulated kinase family, member 3	8	67787444, 67850015	AV690866	23678	8q12.3-q13.1	Hs.613417	30	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding early endosome protein amino acid phosphorylation response to stress cell communication transferase activity cytoplasmic vesicle phosphoinositide binding
212573_at	-0.344	8.451	-2.313	3.513e-02	0.511	-3.739	ENDOD1	endonuclease domain containing 1	11	94462664	AF131747	23052	11q21	Hs.167115	6	nucleic acid binding endonuclease activity extracellular region hydrolase activity metal ion binding	Apoptosis
220422_at	0.193	2.633	2.313	3.513e-02	0.511	-3.739	UBQLN3	ubiquilin 3	11	-5485105	NM_017481	50613	11p15	Hs.189184	6
200882_s_at	-0.252	9.443	-2.312	3.519e-02	0.511	-3.740	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	NM_002810	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
211497_x_at	0.277	4.455	2.311	3.522e-02	0.511	-3.741	NKX3-1	NK3 homeobox 1	8	-23592151	AF249671	4824	8p21	Hs.55999	45	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding	Pathways in cancer Prostate cancer
1555153_s_at	-0.265	2.158	-2.311	3.522e-02	0.511	-3.741	FCHO2	FCH domain only 2	5	72287563	BC014311	115548	5q13.2	Hs.719247	11
209635_at	0.248	5.586	2.311	3.525e-02	0.511	-3.742	AP1S1	adaptor-related protein complex 1, sigma 1 subunit	7	100584405	BC003561	1174	7q22.1	Hs.489365 Hs.718546	26	protein binding Golgi apparatus cytosol coated pit intracellular protein transport receptor-mediated endocytosis protein transporter activity membrane membrane coat AP-1 adaptor complex cytoplasmic vesicle	Lysosome
230807_at	0.231	4.882	2.311	3.525e-02	0.511	-3.742	CCDC151	coiled-coil domain containing 151	19	-11392271	AI807422	115948	19p13.2	Hs.124010	3
1555841_at	0.256	6.235	2.311	3.527e-02	0.511	-3.742	C9orf30	chromosome 9 open reading frame 30	9	102229462	BQ014020	91283	9q31.1	Hs.530272	3
221926_s_at	0.264	5.445	2.310	3.529e-02	0.512	-3.743	IL17RC	interleukin 17 receptor C	3	9933763	BF196320	84818	3p25.3 3p25.3-p24.1	Hs.129959	14	receptor activity plasma membrane integral to membrane
227372_s_at	0.317	4.011	2.310	3.529e-02	0.512	-3.743	BAIAP2L1	BAI1-associated protein 2-like 1	7	-97758903	AA496034	55971	7q21.3-q22.1	Hs.656063 Hs.710371	13	molecular_function actin binding cellular_component signal transduction cytoskeletal adaptor activity biological_process SH3 domain binding filopodium assembly
201724_s_at	-0.234	6.968	-2.310	3.531e-02	0.512	-3.743	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	NM_020474	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
206513_at	-0.210	4.000	-2.310	3.533e-02	0.512	-3.744	AIM2	absent in melanoma 2	1	-157298898	NM_004833	9447	1q22	Hs.281898	11	protein binding nucleus immune response
203227_s_at	-0.293	7.828	-2.310	3.534e-02	0.512	-3.744	TSPAN31	tetraspanin 31	12	56425050	NM_005981	6302	12q13.3	Hs.632708	12	membrane fraction integral to plasma membrane positive regulation of cell proliferation membrane
210299_s_at	-0.362	12.759	-2.308	3.544e-02	0.512	-3.746	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF063002	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
220579_at	-0.234	4.036	-2.308	3.544e-02	0.512	-3.746	FLJ14100	hypothetical protein FLJ14100	1		NM_025025	80093	1p36.33	Hs.711221	1
220753_s_at	0.275	6.227	2.308	3.544e-02	0.512	-3.746	CRYL1	crystallin, lambda 1	13	-19875805	NM_015974	51084	13q12.11	Hs.370703	6	binding cytosol fatty acid metabolic process metabolic process oxidoreductase activity protein homodimerization activity L-gulonate 3-dehydrogenase activity NAD binding
244640_at	0.197	2.477	2.308	3.544e-02	0.512	-3.746	ZNF850P	zinc finger protein 850 pseudogene	19		AW440392	342892	19q13.12	Hs.406307	1	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201993_x_at	-0.217	8.794	-2.308	3.545e-02	0.512	-3.747	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	NM_005463	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
230847_at	0.227	3.855	2.308	3.545e-02	0.512	-3.747	WRNIP1	Werner helicase interacting protein 1	6	2710664	T79870	56897	6p25.2	Hs.236828	14	nucleotide binding DNA synthesis during DNA repair DNA binding protein binding protein binding ATP binding nucleus response to DNA damage stimulus hydrolase activity ATPase activity regulation of DNA replication initiation
209395_at	0.306	2.365	2.308	3.547e-02	0.513	-3.747	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	1	-201414681	M80927	1116	1q32.1	Hs.382202	71	catalytic activity chitinase activity extracellular matrix structural constituent sugar binding extracellular region proteinaceous extracellular matrix extracellular space carbohydrate metabolic process chitin catabolic process cation binding
213778_x_at	-0.179	6.100	-2.307	3.549e-02	0.513	-3.748	ZNF276	zinc finger protein 276	16	88314893, 88315452	AI983201	92822	16q24.3	Hs.290154	8	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
216180_s_at	-0.320	5.900	-2.307	3.553e-02	0.513	-3.749	SYNJ2	synaptojanin 2	6	158322906	AK026758	8871	6q25.3	Hs.434494	18	RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity protein binding membrane dephosphorylation hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
223828_s_at	0.200	3.883	2.306	3.556e-02	0.513	-3.749	LGALS12	lectin, galactoside-binding, soluble, 12	11	63030099, 63032034	AF222694	85329	11q13	Hs.502774	5	sugar binding nucleus mitochondrion apoptosis induction of apoptosis by intracellular signals lactose binding
203089_s_at	0.213	6.857	2.306	3.556e-02	0.513	-3.749	HTRA2	HtrA serine peptidase 2	2	74610039	NM_013247	27429	2p12	Hs.469045 Hs.716372	54	serine-type endopeptidase activity nucleus mitochondrion mitochondrial intermembrane space endoplasmic reticulum endoplasmic reticulum membrane proteolysis apoptosis response to stress mitochondrion organization adult walking behavior peptidase activity induction of apoptosis by intracellular signals membrane integral to membrane forebrain development regulation of multicellular organism growth neuron development unfolded protein binding	Parkinson's disease
215179_x_at	0.210	8.176	2.306	3.556e-02	0.513	-3.749	PGF	placental growth factor	14	-74478290	AK023843	5228	14q24-q31	Hs.252820	79	angiogenesis extracellular region signal transduction cell-cell signaling multicellular organismal development growth factor activity heparin binding positive regulation of cell proliferation membrane cell differentiation	mTOR signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer
217856_at	-0.419	5.399	-2.306	3.557e-02	0.513	-3.749	RBM8A	RNA binding motif protein 8A	1	144218994	AF182415	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
1557079_at	0.329	2.395	2.306	3.557e-02	0.513	-3.750	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	13	100902966	AI753143	9358	13q33	Hs.696554	5	receptor activity binding extracellular region cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex
37965_at	0.301	6.330	2.306	3.558e-02	0.513	-3.750	PARVB	parvin, beta	22	42726505, 42751500	AA181053	29780	22q13.2-q13.33	Hs.475074	18	actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion cell junction	Focal adhesion
1552299_at	-0.221	4.250	-2.306	3.558e-02	0.513	-3.750	AKD1	adenylate kinase domain containing 1	6	-110059592, -109920751	NM_145025	221264	6q21	Hs.205144 Hs.335027 Hs.486169	6	ATP binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process nucleobase, nucleoside, nucleotide kinase activity
208524_at	0.201	4.539	2.306	3.560e-02	0.513	-3.750	GPR15	G protein-coupled receptor 15	3	99733567	NM_005290	2838	3q11.2-q13.1	Hs.563128	11	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway purinergic nucleotide receptor activity, G-protein coupled
200853_at	-0.346	8.798	-2.305	3.563e-02	0.513	-3.751	H2AFZ	H2A histone family, member Z	4	-101088266	NM_002106	3015	4q24	Hs.119192	37	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
238937_at	0.713	5.825	2.305	3.569e-02	0.514	-3.752	ZNF420	zinc finger protein 420	19	42261221	AI339586	147923	19q13.12	Hs.444992	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209185_s_at	-0.948	8.675	-2.305	3.569e-02	0.514	-3.752	IRS2	insulin receptor substrate 2	13	-109204184	AF073310	8660	13q34	Hs.442344	118	positive regulation of mesenchymal cell proliferation signal transducer activity insulin receptor binding plasma membrane signal transduction brain development insulin receptor signaling pathway negative regulation of plasma membrane long-chain fatty acid transport positive regulation of glucose metabolic process regulation of lipid metabolic process protein kinase binding protein domain specific binding positive regulation of cell migration mammary gland development positive regulation of fatty acid beta-oxidation response to peptide hormone stimulus phosphoinositide 3-kinase binding positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of glucose import lipid homeostasis	Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus
215613_at	0.198	3.808	2.305	3.569e-02	0.514	-3.752	ADAM12	ADAM metallopeptidase domain 12	10	-127719902, -127692894	AU145357	8038	10q26.3	Hs.594537	59	metalloendopeptidase activity protein binding extracellular region plasma membrane proteolysis cell adhesion myoblast fusion peptidase activity zinc ion binding integral to membrane SH3 domain binding metal ion binding
228634_s_at	-0.503	6.543	-2.304	3.570e-02	0.514	-3.753	CSDA	cold shock domain protein A	12	-10742944	BF195718	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
226368_at	0.204	4.921	2.304	3.570e-02	0.514	-3.753	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	12	103374907	AI806905	50515	12q	Hs.17569	11	N-acetylgalactosamine 4-O-sulfotransferase activity chondrocyte development Golgi apparatus respiratory gaseous exchange post-embryonic development membrane integral to membrane carbohydrate biosynthetic process transferase activity chondroitin sulfate biosynthetic process negative regulation of transforming growth factor beta receptor signaling pathway polysaccharide localization tail morphogenesis regulation of cell proliferation embryonic digit morphogenesis negative regulation of apoptosis chondroitin 4-sulfotransferase activity developmental growth embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis cartilage development	Chondroitin sulfate biosynthesis Sulfur metabolism
208984_x_at	-0.241	6.098	-2.304	3.571e-02	0.514	-3.753	RBM10	RNA binding motif protein 10	X	46889574, 46889574	BC004181	8241	Xp11.23	Hs.401509	23	nucleotide binding RNA binding intracellular nucleus mRNA processing biological_process zinc ion binding RNA splicing chromatin remodeling complex metal ion binding
218035_s_at	0.205	3.727	2.304	3.573e-02	0.514	-3.754	RBM47	RNA binding motif protein 47	4	-40120028, -40120028	NM_019027	54502	4p13-p12	Hs.518727	4	RNA binding nucleus
213490_s_at	-0.310	6.453	-2.304	3.576e-02	0.514	-3.754	MAP2K2	mitogen-activated protein kinase kinase 2	19	-4041319	AI762811	5605	19p13.3	Hs.465627	98	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding extracellular region protein amino acid phosphorylation Ras protein signal transduction transferase activity	MAPK signaling pathway ErbB signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Pathways in cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
217066_s_at	0.267	6.055	2.303	3.576e-02	0.514	-3.754	DMPK	dystrophia myotonica-protein kinase	19	-50964815, -50964815	M87313	1760	19q13.3	Hs.631596	91	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein modification process protein amino acid phosphorylation regulation of heart contraction transferase activity
218441_s_at	0.232	6.491	2.303	3.578e-02	0.514	-3.755	RPAP1	RNA polymerase II associated protein 1	15	-39596666	NM_015540	26015	15q15.1	Hs.371045	7	DNA binding DNA-directed RNA polymerase activity nucleus transcription transferase activity nucleotidyltransferase activity
1558815_at	0.222	2.717	2.303	3.581e-02	0.514	-3.755	SORBS2	sorbin and SH3 domain containing 2	4	-186743592, -186743592, -186743592, -186743592, -186743592, -186743591, -186743591	BC035329	8470	4q35.1	Hs.619806 Hs.655143	30	structural constituent of cytoskeleton protein binding nucleus cytoplasm cytoskeletal adaptor activity biological_process structural constituent of muscle actin cytoskeleton Z disc perinuclear region of cytoplasm
210479_s_at	-0.561	6.339	-2.303	3.583e-02	0.514	-3.756	RORA	RAR-related orphan receptor A	15	-58567776, -58567776, -58567776	L14611	6095	15q22.2	Hs.560343 Hs.655155	33	transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding
203810_at	-0.482	8.517	-2.302	3.584e-02	0.514	-3.756	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1	78243223	BG252490	11080	1p31.1	Hs.13852	11	protein folding response to unfolded protein response to heat heat shock protein binding unfolded protein binding
219094_at	-0.297	3.116	-2.302	3.588e-02	0.515	-3.757	ARMC8	armadillo repeat containing 8	3	139388837, 139388837	NM_014154	25852	3q22.3	Hs.719108	4	binding
222447_at	-0.343	7.726	-2.302	3.590e-02	0.515	-3.757	METTL9	methyltransferase like 9	16	21518356	BC000195	51108	16p13-p12	Hs.279583	6
227279_at	0.453	7.300	2.301	3.592e-02	0.515	-3.758	TCEAL3	transcription elongation factor A (SII)-like 3	X	102749489	AA847654	85012	Xq22.2	Hs.311776	6	nucleus regulation of transcription
219131_at	-0.168	5.837	-2.301	3.593e-02	0.515	-3.758	UBIAD1	UbiA prenyltransferase domain containing 1	1	11255841	NM_013319	29914	1p36-p34.1	Hs.522933	15	prenyltransferase activity nucleus cytoplasm membrane integral to membrane
1568780_at	0.464	3.280	2.301	3.593e-02	0.515	-3.758	LOC649305	hypothetical LOC649305	8		BC030211	649305		Hs.638932	1
203405_at	-0.333	6.521	-2.301	3.594e-02	0.515	-3.759	PSMG1	proteasome (prosome, macropain) assembly chaperone 1	21	-39469253	NM_003720	8624	21q22.3	Hs.473838	12	protein binding cytoplasm endoplasmic reticulum proteasome assembly
207453_s_at	-0.381	6.474	-2.300	3.597e-02	0.515	-3.759	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	9	34979724, 34980266	NM_012266	25822	9p13.3	Hs.237506	5	protein folding response to unfolded protein heat shock protein binding unfolded protein binding
216199_s_at	0.268	7.761	2.300	3.601e-02	0.515	-3.760	MAP3K4	mitogen-activated protein kinase kinase kinase 4	6	161332811	AL109942	4216	6q26	Hs.390428	20	nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding response to stress JNK cascade transferase activity	MAPK signaling pathway GnRH signaling pathway
222985_at	-0.202	11.964	-2.300	3.602e-02	0.515	-3.760	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	7	-75794043	AB024334	7532	7q11.23	Hs.520974	56	protein kinase C binding insulin-like growth factor receptor binding cytoplasm negative regulation of protein kinase activity protein targeting protein kinase C inhibitor activity regulation of signal transduction protein domain specific binding regulation of neuron differentiation regulation of synaptic plasticity	Cell cycle Neurotrophin signaling pathway
208876_s_at	0.210	3.422	2.300	3.603e-02	0.515	-3.761	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	3	197951124	AI076186	5062	3q29	Hs.518530	80	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol negative regulation of protein kinase activity apoptosis signal transduction membrane transferase activity regulation of growth identical protein binding interspecies interaction between organisms protein amino acid autophosphorylation perinuclear region of cytoplasm	MAPK signaling pathway ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
229055_at	0.261	5.298	2.300	3.603e-02	0.515	-3.761	GPR68	G protein-coupled receptor 68	14	-90768628	AI805006	8111	14q31	Hs.8882	14	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane inflammatory response signal transduction G-protein coupled receptor protein signaling pathway
227195_at	0.482	5.934	2.299	3.604e-02	0.515	-3.761	ZNF503	zinc finger protein 503	10	-76827610	AA603467	84858	10q22.2	Hs.195710	6	intracellular nucleus zinc ion binding regulation of transcription metal ion binding
218955_at	-0.216	7.480	-2.299	3.606e-02	0.515	-3.761	BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	8	-37820560	NM_018310	55290	8p11.23	Hs.709301	11	protein binding nucleus transcription factor complex transcription initiation regulation of transcription, DNA-dependent zinc ion binding transcription regulator activity metal ion binding
229274_at	0.446	5.100	2.299	3.608e-02	0.515	-3.762	GNAS	GNAS complex locus	20	56848189, 56861430, 56897574, 56899819, 56899820, 56900163	AI693143	2778	20q13.3	Hs.125898 Hs.694849	221	nucleotide binding ruffle molecular_function GTPase activity signal transducer activity GTP binding extracellular region membrane fraction cytoplasm cytoplasm heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway activation of adenylate cyclase activity female pregnancy sensory perception of smell protein secretion hormone-mediated signaling guanyl nucleotide binding intrinsic to membrane mu-type opioid receptor binding vesicle trans-Golgi network membrane sarcolemma identical protein binding intracellular transport	Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term depression Taste transduction GnRH signaling pathway Melanogenesis Vibrio cholerae infection
231973_s_at	-0.490	4.745	-2.299	3.609e-02	0.515	-3.762	ANAPC1	anaphase promoting complex subunit 1	2	-112243110	AK001223	64682	2q12.1	Hs.436527	26	nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
232722_at	0.173	3.025	2.299	3.611e-02	0.515	-3.762	RNASET2	ribonuclease T2	6	-167262993	AK001769	8635	6q27	Hs.529989	11	RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity
209741_x_at	0.422	7.092	2.299	3.611e-02	0.515	-3.763	SCAPER	S-phase cyclin A-associated protein in the ER	15	-74427583, -74427583	AF119814	49855	15q24	Hs.458986	7	intracellular nucleus endoplasmic reticulum zinc ion binding metal ion binding
222230_s_at	0.284	9.811	2.298	3.612e-02	0.515	-3.763	ACTR10	actin-related protein 10 homolog (S. cerevisiae)	14	57736585	AK022248	55860	14q23.1	Hs.509451	7	protein binding cytoplasm cytoskeleton dynactin complex microtubule-based movement
227598_at	0.213	3.757	2.298	3.614e-02	0.515	-3.763	C7orf29	chromosome 7 open reading frame 29	7	149657870	AI762857	113763	7q36.1	Hs.655915	4
1555867_at	0.191	2.676	2.298	3.615e-02	0.515	-3.763	GNG4	guanine nucleotide binding protein (G protein), gamma 4	1	-233777607, -233777607	BM666010	2786	1q42.3	Hs.159711	13	signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling negative regulation of cell growth	Chemokine signaling pathway
50400_at	0.177	4.793	2.298	3.617e-02	0.516	-3.764	PAOX	polyamine oxidase (exo-N4-amino)	10	135042730	AI743990	196743	10q26.3	Hs.532469	8
212032_s_at	-0.293	7.334	-2.297	3.619e-02	0.516	-3.764	PTOV1	prostate tumor overexpressed 1	19	55046227	AL046054	53635	19q13.33	Hs.587979	11	nucleus cytoplasm plasma membrane regulation of transcription perinuclear region of cytoplasm
208842_s_at	-0.221	7.657	-2.297	3.622e-02	0.516	-3.765	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	W93787	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
1553626_a_at	-0.202	2.337	-2.297	3.623e-02	0.516	-3.765	C17orf57	chromosome 17 open reading frame 57	17	42756348	NM_152347	124989	17q21.32	Hs.463303	2	calcium ion binding
226658_at	-0.374	4.837	-2.297	3.623e-02	0.516	-3.765	PDPN	podoplanin	1	13782838, 13784553	AW590196	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
207695_s_at	0.480	4.624	2.297	3.623e-02	0.516	-3.765	IGSF1	immunoglobulin superfamily, member 1	X	-130245822, -130235162	NM_001555	3547	Xq25	Hs.22111	15	receptor activity protein binding extracellular region signal transduction membrane integral to membrane regulation of transcription inhibin beta-A binding inhibin beta-B binding
1560078_at	-0.216	4.273	-2.297	3.623e-02	0.516	-3.766	LAMA3	laminin, alpha 3	18	19523559, 19706981	AL708055	3909	18q11.2	Hs.436367	49	receptor binding structural molecule activity extracellular region basement membrane laminin-1 complex epidermis development regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
225402_at	-0.384	4.989	-2.296	3.629e-02	0.516	-3.767	TP53RK	TP53 regulating kinase	20	-44746410	BG339450	112858	20q13.2	Hs.440263	12	nucleotide binding p53 binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity
1564300_at	0.251	3.458	2.295	3.633e-02	0.516	-3.768	LOC100129058	similar to hCG2038656	3		AK097471	100129058	3p21.2		1
213116_at	0.273	5.404	2.295	3.633e-02	0.516	-3.768	NEK3	NIMA (never in mitosis gene a)-related kinase 3	13	-51604780, -51604779, -51604779	AI191920	4752	13q14.13	Hs.409989	12	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation cell cycle mitosis transferase activity cell division
217467_at	0.178	3.159	2.295	3.634e-02	0.516	-3.768	BTF3	basic transcription factor 3	5	72830005	M90356	689	5q13.2	Hs.591768	12	RNA polymerase II transcription factor activity protein binding nucleus transcription from RNA polymerase II promoter regulation of transcription
1557227_s_at	-0.219	3.072	-2.295	3.634e-02	0.516	-3.768	TPR	translocated promoter region (to activated MET oncogene)	1	-184547408	AW235355	7175	1q25	Hs.279640	30	nucleotide binding kinetochore serine-tRNA ligase activity protein binding ATP binding nucleus nuclear pore nucleoplasm cytoplasm translation seryl-tRNA aminoacylation protein import into nucleus mitotic cell cycle spindle assembly checkpoint protein transport membrane mRNA transport intracellular protein transmembrane transport	Pathways in cancer Thyroid cancer
219585_at	-0.301	5.123	-2.295	3.637e-02	0.516	-3.769	CCDC28B	coiled-coil domain containing 28B	1	32438788	NM_024296	79140	1p35.1	Hs.718470	10
211105_s_at	-0.615	7.707	-2.295	3.637e-02	0.516	-3.769	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	18	75256759, 75256759, 75261313	U80918	4772	18q23	Hs.534074 Hs.701518	83	transcription factor activity FK506 binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter intracellular signaling cascade transcription activator activity	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
235025_at	-0.257	2.571	-2.295	3.638e-02	0.516	-3.769	WDR89	WD repeat domain 89	14	-63133509, -63133509	AW196959	112840	14q23.2	Hs.655666	6
206117_at	-0.409	13.220	-2.295	3.638e-02	0.516	-3.769	TPM1	tropomyosin 1 (alpha)	15	61121890, 61121890, 61127688	NM_000366	7168	15q22.1	Hs.133892	76	stress fiber positive regulation of heart rate by epinephrine actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction cytoskeleton organization regulation of heart contraction structural constituent of muscle sarcomere muscle filament sliding negative regulation of cell migration ruffle organization bleb ruffle membrane positive regulation of ATPase activity cellular response to reactive oxygen species wound healing sarcomere organization positive regulation of cell adhesion positive regulation of stress fiber formation ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
229177_at	0.230	5.551	2.294	3.641e-02	0.516	-3.770	C16orf89	chromosome 16 open reading frame 89	16	-5034123	AI823572	146556	16p13.3	Hs.11782	4	extracellular region
201181_at	-0.230	4.746	-2.294	3.642e-02	0.516	-3.770	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	1	109892708	NM_006496	2773	1p13	Hs.73799	54	nucleotide binding GTPase activity signal transducer activity protein binding GTP binding cytoplasm Golgi apparatus transport signal transduction G-protein coupled receptor protein signaling pathway negative regulation of adenylate cyclase activity guanyl nucleotide binding	Chemokine signaling pathway Axon guidance Tight junction Gap junction Leukocyte transendothelial migration Long-term depression Melanogenesis
232073_at	-0.254	4.127	-2.294	3.642e-02	0.516	-3.770	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	12	-80177486	AL157453	8499	12q21.31	Hs.506216	7	protein binding cytoplasm cell-matrix adhesion cell surface
244680_at	0.270	3.784	2.294	3.644e-02	0.516	-3.770	GLRB	glycine receptor, beta	4	158216726	AI701428	2743	4q31.3	Hs.32973	14	startle response ion channel activity extracellular ligand-gated ion channel activity protein binding membrane fraction plasma membrane integral to plasma membrane ion transport chloride transport neuropeptide signaling pathway synaptic transmission acrosome reaction nervous system development visual perception adult walking behavior glycine binding extracellular-glycine-gated chloride channel activity cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex regulation of membrane potential synapse postsynaptic membrane synaptic transmission, glycinergic righting reflex	Neuroactive ligand-receptor interaction
1568377_x_at	0.212	5.890	2.294	3.645e-02	0.516	-3.771	DEFB124	defensin, beta 124	20	-29516969	AY122476	245937	20q11.1	Hs.381373	3	extracellular region defense response to bacterium
201581_at	-0.341	8.777	-2.294	3.645e-02	0.516	-3.771	TMX4	thioredoxin-related transmembrane protein 4	20	-7909715	BF572868	56255	20p12	Hs.169358	11	mitochondrion transport membrane integral to membrane electron transport chain cell redox homeostasis
223601_at	0.184	3.061	2.293	3.650e-02	0.517	-3.772	OLFM2	olfactomedin 2	19	-9825393	AF131839	93145	19p13.2	Hs.169743	9	extracellular region
211570_s_at	-0.291	6.748	-2.293	3.650e-02	0.517	-3.772	RAPSN	receptor-associated protein of the synapse	11	-47415890	BC004196	5913	11p11.2-p11.1	Hs.81218	32	protein binding cytoplasm Golgi apparatus cytoskeleton plasma membrane synaptic transmission zinc ion binding cell junction neuromuscular junction acetylcholine receptor binding postsynaptic membrane metal ion binding
202959_at	0.305	6.260	2.293	3.651e-02	0.517	-3.772	MUT	methylmalonyl Coenzyme A mutase	6	-49506949	AI433712	4594	6p12.3	Hs.485527	42	methylmalonyl-CoA mutase activity mitochondrion mitochondrial matrix metabolic process post-embryonic development cobalamin binding metal ion binding cobalt ion binding	Valine, leucine and isoleucine degradation Propanoate metabolism Metabolic pathways
1554029_a_at	-0.328	2.907	-2.293	3.652e-02	0.517	-3.772	TTC37	tetratricopeptide repeat domain 37	5	-94825877	BC030966	9652	5q15	Hs.482868	4	binding	RNA degradation
237795_s_at	0.238	3.967	2.292	3.654e-02	0.517	-3.773	SP2	Sp2 transcription factor	17	43328514	AW294585	6668	17q21.32	Hs.514276	18	DNA binding RNA polymerase II transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter immune response zinc ion binding histone deacetylase binding regulation of transcription metal ion binding
219504_s_at	-0.218	5.810	-2.292	3.658e-02	0.517	-3.774	RPAP2	RNA polymerase II associated protein 2	1	92537109	NM_024813	79871	1p22.1	Hs.444421	7	membrane integral to membrane
244206_at	-0.308	3.169	-2.292	3.658e-02	0.517	-3.774	ANUBL1	AN1, ubiquitin-like, homolog (Xenopus laevis)	10	-45431044	AW469676	93550	10q11.22	Hs.89029	5	zinc ion binding metal ion binding
212426_s_at	0.324	8.305	2.292	3.659e-02	0.517	-3.774	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	2	-9641556	BF033313	10971	2p25.1	Hs.74405	93	cytoplasm protein targeting small GTPase mediated signal transduction protein domain specific binding negative regulation of transcription, DNA-dependent protein N-terminus binding	Cell cycle Neurotrophin signaling pathway Pathogenic Escherichia coli infection - EHEC
225908_at	0.213	8.659	2.292	3.660e-02	0.517	-3.774	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	2	9532120	AI829927	285148	2p25.1	Hs.614939	2	lipid catabolic process hydrolase activity, acting on ester bonds
229725_at	0.379	3.710	2.291	3.662e-02	0.517	-3.775	ACSL6	acyl-CoA synthetase long-chain family member 6	5	-131317050	AV705292	23305	5q31	Hs.14945	15	nucleotide binding magnesium ion binding long-chain-fatty-acid-CoA ligase activity ATP binding mitochondrion mitochondrial outer membrane peroxisome peroxisomal membrane endoplasmic reticulum microsome plasma membrane lipid metabolic process acyl-CoA metabolic process metabolic process integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
208365_s_at	0.240	4.154	2.291	3.663e-02	0.517	-3.775	GRK4	G protein-coupled receptor kinase 4	4	2935140	NM_005307	2868	4p16.3	Hs.32959	27	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity ATP binding protein amino acid phosphorylation signal transduction regulation of G-protein coupled receptor protein signaling pathway transferase activity	Chemokine signaling pathway Endocytosis
228820_at	-0.330	6.222	-2.290	3.668e-02	0.517	-3.776	XPNPEP3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative	22	39583039	BE674036	63929	22q13.31-q13.33	Hs.529163	7	aminopeptidase activity mitochondrion peptidase activity metallopeptidase activity cellular process manganese ion binding metal ion binding
1555626_a_at	0.216	5.154	2.290	3.668e-02	0.517	-3.776	SLAMF1	signaling lymphocytic activation molecule family member 1	1	-158846514	BC012602	6504	1q22-q23	Hs.523660	36	antigen binding transmembrane receptor activity plasma membrane positive regulation of cell proliferation cell surface integral to membrane interspecies interaction between organisms lymphocyte activation
213364_s_at	0.341	6.728	2.290	3.669e-02	0.517	-3.776	SNX1	sorting nexin 1	15	62175229	AI052536	6642	15q22.31	Hs.188634	28	protein binding cytoplasm endosome Golgi apparatus intracellular protein transport endocytosis cell communication protein transporter activity membrane phosphoinositide binding
240859_at	0.357	5.232	2.290	3.670e-02	0.517	-3.777	ZFYVE16	zinc finger, FYVE domain containing 16	5	79739593	N20928	9765	5q14	Hs.482660 Hs.660410	15	protein binding phosphatidylinositol binding cytoplasm protein targeting to lysosome signal transduction zinc ion binding protein transporter activity membrane vesicle organization endosome transport regulation of endocytosis BMP signaling pathway early endosome membrane metal ion binding	TGF-beta signaling pathway
221599_at	0.382	9.311	2.290	3.670e-02	0.517	-3.777	C11orf67	chromosome 11 open reading frame 67	11	77209855	BC002752	28971	11q14.1	Hs.503357	3
231140_at	-0.274	4.792	-2.290	3.671e-02	0.517	-3.777	TPPP2	tubulin polymerization-promoting protein family member 2	14	20568184	AA913948	122664	14q11.2	Hs.406966	5
204382_at	-0.189	6.234	-2.290	3.673e-02	0.517	-3.777	NAT9	N-acetyltransferase 9 (GCN5-related, putative)	17	-70278280	NM_015654	26151	17q25.1	Hs.144058	12	N-acetyltransferase activity metabolic process acyltransferase activity transferase activity protein complex
244527_at	0.209	3.058	2.290	3.673e-02	0.517	-3.777	TRIO	triple functional domain (PTPRF interacting)	5	14196828	BG055304	7204	5p15.2	Hs.130031	22	nucleotide binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity ATP binding intracellular cytoplasm protein amino acid phosphorylation transmembrane receptor protein tyrosine phosphatase signaling pathway transferase activity regulation of Rho protein signal transduction
210298_x_at	-0.508	11.878	-2.290	3.674e-02	0.517	-3.777	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF098518	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
1556573_s_at	-0.179	4.715	-2.289	3.676e-02	0.517	-3.778	LOC286178	hypothetical protein LOC286178	8		AK090741	286178	8q12.1	Hs.255156	1
204875_s_at	0.187	2.407	2.289	3.680e-02	0.517	-3.779	GMDS	GDP-mannose 4,6-dehydratase	6	-1569039	NM_001500	2762	6p25	Hs.144496 Hs.660919	11	binding intracellular cytoplasm carbohydrate metabolic process leukocyte adhesion GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process cellular metabolic process coenzyme binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
212554_at	-0.252	11.653	-2.289	3.680e-02	0.517	-3.779	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6	17501714	N90755	10486	6p22.3	Hs.132902	7	actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity
231869_at	-0.193	2.489	-2.289	3.680e-02	0.517	-3.779	KIAA1586	KIAA1586	6	57019342	BF339845	57691	6p12.1	Hs.709521	2
208941_s_at	0.212	6.086	2.288	3.682e-02	0.517	-3.779	SEPHS1	selenophosphate synthetase 1	10	-13400086	BC000941	22929	10p14	Hs.124027	8	nucleotide binding selenide, water dikinase activity ATP binding GTP binding protein modification process selenium binding transferase activity	Selenoamino acid metabolism Metabolic pathways
222750_s_at	0.449	5.174	2.288	3.682e-02	0.517	-3.779	SRD5A3	steroid 5 alpha-reductase 3	4	55907165	BC002480	79644	4q12	Hs.39311	3	3-oxo-5-alpha-steroid 4-dehydrogenase activity cytoplasm endoplasmic reticulum microsome lipid metabolic process membrane integral to membrane oxidoreductase activity, acting on the CH-CH group of donors oxidation reduction	Androgen and estrogen metabolism
207553_at	0.239	3.804	2.288	3.685e-02	0.517	-3.780	OPRK1	opioid receptor, kappa 1	8	-54300828	NM_000912	4986	8q11.2	Hs.106795	46	receptor activity G-protein coupled receptor activity kappa-opioid receptor activity protein binding plasma membrane integral to plasma membrane immune response signal transduction G-protein coupled receptor protein signaling pathway inhibition of adenylate cyclase activity by G-protein signaling synaptic transmission sensory perception behavior viral genome replication	Neuroactive ligand-receptor interaction
242816_at	-0.211	3.767	-2.288	3.686e-02	0.517	-3.780	GNAS	GNAS complex locus	20	56848189, 56861430, 56897574, 56899819, 56899820, 56900163	AI339489	2778	20q13.3	Hs.125898 Hs.694849	221	nucleotide binding ruffle molecular_function GTPase activity signal transducer activity GTP binding extracellular region membrane fraction cytoplasm cytoplasm heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway activation of adenylate cyclase activity female pregnancy sensory perception of smell protein secretion hormone-mediated signaling guanyl nucleotide binding intrinsic to membrane mu-type opioid receptor binding vesicle trans-Golgi network membrane sarcolemma identical protein binding intracellular transport	Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term depression Taste transduction GnRH signaling pathway Melanogenesis Vibrio cholerae infection
1560112_at	0.209	2.600	2.288	3.688e-02	0.517	-3.781	WDFY2	WD repeat and FYVE domain containing 2	13	51056484	AK054833	115825	13q14.3	Hs.208550	7	zinc ion binding metal ion binding
201816_s_at	-0.293	11.867	-2.287	3.689e-02	0.517	-3.781	GBAS	glioblastoma amplified sequence	7	55999789	NM_001483	2631	7p12	Hs.591069	9	membrane fraction mitochondrion integral to plasma membrane
219044_at	0.645	6.569	2.287	3.690e-02	0.517	-3.781	THNSL2	threonine synthase-like 2 (S. cerevisiae)	2	88250949	NM_018271	55258	2p11.2	Hs.516179	6	metabolic process lyase activity pyridoxal phosphate binding
203529_at	-0.271	9.073	-2.287	3.691e-02	0.517	-3.781	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	NM_016294	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
204003_s_at	0.210	6.583	2.287	3.692e-02	0.517	-3.782	NUPL2	nucleoporin like 2	7	23187970	NM_007342	11097	7p15	Hs.408241	13	nucleic acid binding nuclear export signal receptor activity nucleus nuclear pore cytosol protein export from nucleus zinc ion binding protein transport membrane metal ion binding mRNA transport intracellular protein transmembrane transport
238123_at	0.261	4.134	2.287	3.692e-02	0.517	-3.782	GABRQ	gamma-aminobutyric acid (GABA) receptor, theta	X	151557292	W52448	55879	Xq28	Hs.283081	8	transmembrane receptor activity GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity neurotransmitter transporter activity plasma membrane integral to plasma membrane ion transport signal transduction cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
51158_at	0.216	4.303	2.287	3.692e-02	0.517	-3.782	FAM174B	family with sequence similarity 174, member B	15	-90961682	AI801973	400451	15q26.1	Hs.27373 Hs.702316	2	membrane integral to membrane
204279_at	0.359	6.795	2.287	3.692e-02	0.517	-3.782	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	6	32929915, 4202792, 4007991	NM_002800	5698	6p21.3	Hs.654585	72	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex immune response peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
202207_at	0.811	4.276	2.287	3.694e-02	0.517	-3.782	ARL4C	ADP-ribosylation factor-like 4C	2	-235066424	BG435404	10123	2q37.1	Hs.111554 Hs.719190	7	nucleotide binding GTPase activity GTP binding intracellular nucleus small GTPase mediated signal transduction
215960_at	0.198	4.066	2.287	3.694e-02	0.517	-3.782	SLC5A4	solute carrier family 5 (low affinity glucose cotransporter), member 4	22	-30944464	AJ133127	6527	22q12.2-q12.3	Hs.130101	8	transporter activity ion transport sodium ion transport carbohydrate transport symporter activity membrane integral to membrane sodium ion binding
226824_at	0.328	5.401	2.286	3.696e-02	0.517	-3.783	CPXM2	carboxypeptidase X (M14 family), member 2	10	-125495141	AW513612	119587	10q26.13	Hs.656887	5	metallocarboxypeptidase activity extracellular region proteolysis cell adhesion zinc ion binding
214515_at	0.214	4.024	2.286	3.697e-02	0.517	-3.783	OR1E1	olfactory receptor, family 1, subfamily E, member 1	17	-3247509	NM_003553	8387	17p13.3	Hs.278485	7	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
202574_s_at	0.367	6.889	2.286	3.699e-02	0.517	-3.783	CSNK1G2	casein kinase 1, gamma 2	19	1892160	NM_001319	1455	19p13.3	Hs.651905	16	nucleotide binding protein serine/threonine kinase activity ATP binding cytoplasm protein amino acid phosphorylation signal transduction Wnt receptor signaling pathway transferase activity	Hedgehog signaling pathway
232457_at	0.294	4.822	2.286	3.700e-02	0.517	-3.784	LIMCH1	LIM and calponin homology domains 1	4	41057560, 41309675	AU147704	22998	4p13	Hs.335163	10	actin binding zinc ion binding actomyosin structure organization metal ion binding
219890_at	-0.235	2.952	-2.286	3.701e-02	0.517	-3.784	CLEC5A	C-type lectin domain family 5, member A	7	-141273625	NM_013252	23601	7q33	Hs.446235	8	binding sugar binding integral to plasma membrane immune response cellular defense response signal transduction membrane
203424_s_at	-0.494	6.756	-2.286	3.703e-02	0.517	-3.784	IGFBP5	insulin-like growth factor binding protein 5	2	-217245072	AW157548	3488	2q33-q36	Hs.607212	90	regulation of cell growth osteoblast differentiation extracellular region signal transduction negative regulation of smooth muscle cell migration insulin-like growth factor binding protein complex negative regulation of translation insulin-like growth factor I binding negative regulation of insulin-like growth factor receptor signaling pathway negative regulation of smooth muscle cell proliferation
214411_x_at	0.210	5.412	2.285	3.704e-02	0.517	-3.785	CTRB2	chymotrypsinogen B2	16	-73795494	AW584011	440387	16q23.1	Hs.632211	6	serine-type endopeptidase activity extracellular region extracellular space proteolysis digestion peptidase activity
201892_s_at	-0.325	9.409	-2.285	3.707e-02	0.518	-3.785	IMPDH2	IMP (inosine monophosphate) dehydrogenase 2	3	-49036765	NM_000884	3615	3p21.2	Hs.654400	31	IMP dehydrogenase activity IMP dehydrogenase activity protein binding cytosol purine nucleotide biosynthetic process GMP biosynthetic process oxidoreductase activity potassium ion binding lymphocyte proliferation metal ion binding oxidation reduction	Purine metabolism Drug metabolism - other enzymes Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
235539_at	-0.242	3.344	-2.284	3.713e-02	0.518	-3.787	NUMA1	nuclear mitotic apparatus protein 1	11	-71391558	AW964431	4926	11q13	Hs.325978	47	mitotic anaphase spindle pole structural molecule activity protein binding nucleus spindle microtubule nucleus organization microtubule binding nuclear matrix dendrite cell soma meiotic cell cycle
215250_at	0.332	5.473	2.284	3.713e-02	0.518	-3.787	TMEM111	transmembrane protein 111	3	-9980635	AU147317	55831	3p25.3	Hs.475392	6	molecular_function cellular_component biological_process membrane integral to membrane
1564787_at	0.216	4.802	2.284	3.715e-02	0.518	-3.787	LOC643923	hypothetical protein LOC643923	11	106967680	AK058066	643923	11q22.3	Hs.647220
225045_at	0.226	5.965	2.284	3.717e-02	0.518	-3.787	CCDC88A	coiled-coil domain containing 88A	2	-55368483	AB033038	55704	2p16.1	Hs.292925	13	regulation of protein amino acid phosphorylation actin binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane regulation of DNA replication microtubule binding membrane organization cell migration lamellipodium lamellipodium assembly cytoplasmic vesicle activation of protein kinase B activity regulation of actin cytoskeleton organization phosphoinositide binding regulation of cell proliferation protein homodimerization activity protein kinase B binding
210568_s_at	-0.243	4.693	-2.284	3.717e-02	0.518	-3.788	RECQL	RecQ protein-like (DNA helicase Q1-like)	12	-21513111	BC001052	5965	12p12	Hs.235069	29	nucleotide binding DNA strand renaturation DNA strand annealing activity DNA binding ATP-dependent DNA helicase activity protein binding ATP binding nucleus DNA repair DNA recombination hydrolase activity
213564_x_at	0.660	11.752	2.283	3.719e-02	0.518	-3.788	LDHB	lactate dehydrogenase B	12	-21679542	BE042354	3945	12p12.2-p12.1	Hs.446149	27	L-lactate dehydrogenase activity binding cytoplasm oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
207040_s_at	-0.299	10.356	-2.283	3.719e-02	0.518	-3.788	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22	-39550546	NM_003932	6767	22q13.2	Hs.712713	29	binding cytoplasm protein folding protein binding, bridging
209112_at	-0.356	9.602	-2.283	3.719e-02	0.518	-3.788	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	12	12761568	BC001971	1027	12p13.1-p12	Hs.238990	442	regulation of cyclin-dependent protein kinase activity G1/S transition of mitotic cell cycle protein kinase inhibitor activity cyclin-dependent protein kinase inhibitor activity transforming growth factor beta receptor, cytoplasmic mediator activity protein binding nucleus cytoplasm cytosol induction of apoptosis cell cycle cell cycle arrest negative regulation of cell proliferation negative regulation of cell growth negative regulation of gene-specific transcription negative regulation of kinase activity negative regulation of phosphorylation autophagic cell death	ErbB signaling pathway Cell cycle Pathways in cancer Prostate cancer Chronic myeloid leukemia Small cell lung cancer
221017_s_at	-0.232	3.523	-2.282	3.731e-02	0.519	-3.791	LRRC3	leucine rich repeat containing 3	21	44699820	NM_030891	81543	21q22.3	Hs.326579	5	protein binding membrane integral to membrane
214277_at	0.384	4.423	2.282	3.731e-02	0.519	-3.791	COX11	COX11 homolog, cytochrome c oxidase assembly protein (yeast)	17	-50393566, -50384257	AI376724	1353	17q22	Hs.591171	8	cytochrome-c oxidase activity copper ion binding mitochondrion mitochondrial inner membrane respiratory gaseous exchange respiratory chain complex IV assembly electron carrier activity membrane integral to membrane	Oxidative phosphorylation Metabolic pathways
213089_at	0.373	6.696	2.282	3.732e-02	0.519	-3.791	LOC100272216	hypothetical LOC100272216	5	-68962735, -639139, 931828	AU158490	100272216		Hs.631974
224345_x_at	0.269	10.762	2.281	3.733e-02	0.519	-3.791	FAM162A	family with sequence similarity 162, member A	3	123585712	AF107495	26355	3q21.1	Hs.584881	8	membrane integral to membrane
221674_s_at	0.159	5.098	2.281	3.733e-02	0.519	-3.791	CHRD	chordin	3	185580554	AF209929	8646	3q27	Hs.166186	21	skeletal system development extracellular region extracellular space multicellular organismal development cytokine binding BMP signaling pathway in spinal cord dorsal/ventral patterning negative regulation of cell migration negative regulation of BMP signaling pathway floor plate development positive regulation of cell adhesion	TGF-beta signaling pathway
AFFX-HUMGAPDH/M33197_3_at	-0.180	13.587	-2.281	3.736e-02	0.519	-3.792	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	AFFX-HUMGAPDH/M33197_3	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
204595_s_at	-0.190	4.697	-2.281	3.739e-02	0.519	-3.793	STC1	stanniocalcin 1	8	-23755378	AI300520	6781	8p21-p11.2	Hs.25590	35	hormone activity extracellular region extracellular space cellular calcium ion homeostasis cell surface receptor linked signal transduction cell-cell signaling response to nutrient
211822_s_at	0.226	3.591	2.281	3.739e-02	0.519	-3.793	NLRP1	NLR family, pyrin domain containing 1	17	-5358161, -5345442	AF229061	22861	17p13.2	Hs.652273	31	nucleotide binding ATP binding intracellular nucleus cytoplasm induction of apoptosis activation of caspase activity defense response caspase activator activity enzyme binding protein domain specific binding regulation of apoptosis neuron apoptosis
212871_at	-0.395	5.925	-2.280	3.741e-02	0.519	-3.793	MAPKAPK5	mitogen-activated protein kinase-activated protein kinase 5	12	110764661	NM_003668	8550	12q24.12-q24.13	Hs.413901	16	nucleotide binding protein serine/threonine kinase activity MAP kinase kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction transferase activity	MAPK signaling pathway
209693_at	-0.217	5.514	-2.280	3.742e-02	0.519	-3.793	ASTN2	astrotactin 2	9	-118227327, -118227327	AF116574	23245	9q33.1	Hs.601562	6	membrane integral to membrane
224954_at	0.202	7.494	2.280	3.743e-02	0.519	-3.794	SHMT1	serine hydroxymethyltransferase 1 (soluble)	17	-18171911	Y14486	6470	17p11.2	Hs.513987 Hs.636044	64	glycine hydroxymethyltransferase activity glycine hydroxymethyltransferase activity cytoplasm cytosol cytosol glycine metabolic process L-serine catabolic process one-carbon metabolic process purine base biosynthetic process transferase activity pyridoxal phosphate binding protein homodimerization activity folic acid metabolic process protein tetramerization	Glycine, serine and threonine metabolism Cyanoamino acid metabolism One carbon pool by folate Methane metabolism Metabolic pathways
1556804_s_at	0.358	2.600	2.280	3.745e-02	0.519	-3.794	POLR3B	polymerase (RNA) III (DNA directed) polypeptide B	12	105275565, 105275989	BC033542	55703	12q23.3	Hs.610795 Hs.62696	8	DNA binding DNA-directed RNA polymerase activity nucleus transcription zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
213213_at	0.228	5.781	2.280	3.745e-02	0.519	-3.794	DIDO1	death inducer-obliterator 1	20	-61006799, -61006799, -60989013, -60979534	AL035669	11083	20q13.33	Hs.517172	18	protein binding nucleus cytoplasm transcription apoptosis zinc ion binding metal ion binding
206546_at	-0.205	2.492	-2.279	3.748e-02	0.519	-3.795	SYCP2	synaptonemal complex protein 2	20	-57872012	NM_014258	10388	20q13.33	Hs.202676	4	lateral element DNA binding protein binding nucleus apoptosis cell cycle meiotic prophase I synaptonemal complex assembly male meiosis female meiosis fertilization organ morphogenesis protein heterodimerization activity male genitalia morphogenesis cell division
1561579_at	0.221	4.195	2.279	3.748e-02	0.519	-3.795	LOC728445	hypothetical protein LOC728445	8		AI240136	728445	8p11.21	Hs.713375
1556725_a_at	0.183	2.204	2.279	3.748e-02	0.519	-3.795	LOC100128398	hypothetical protein LOC100128398	19		BC036750	100128398	19q13.43	Hs.655081	1
224922_at	-0.248	5.925	-2.279	3.750e-02	0.519	-3.795	CSNK2A2	casein kinase 2, alpha prime polypeptide	16	-56749312	AI022089	1459	16q21	Hs.82201	143	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity protein N-terminus binding regulation of cell cycle	Wnt signaling pathway Adherens junction Tight junction
224277_at	-0.203	2.613	-2.278	3.754e-02	0.519	-3.796	MOP-1	MOP-1	4		AB014771	643616	4q21.22	Hs.679418
230475_at	0.303	5.722	2.278	3.756e-02	0.519	-3.797	C15orf59	chromosome 15 open reading frame 59	15	-71819193	AI368415	388135	15q24.1	Hs.40794	1
205943_at	0.755	3.134	2.278	3.757e-02	0.519	-3.797	TDO2	tryptophan 2,3-dioxygenase	4	157044296	NM_005651	6999	4q31-q32	Hs.183671	16	tryptophan 2,3-dioxygenase activity tryptophan 2,3-dioxygenase activity iron ion binding cytosol oxidoreductase activity tryptophan catabolic process to kynurenine NAD metabolic process metal ion binding oxidation reduction	Tryptophan metabolism Metabolic pathways
202803_s_at	0.290	5.036	2.278	3.758e-02	0.519	-3.797	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	21	-45130296, -45130296	NM_000211	3689	21q22.3	Hs.375957	243	glycoprotein binding receptor activity cytoplasm plasma membrane plasma membrane apoptosis inflammatory response cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway cell-cell signaling integrin complex regulation of cell shape integral to membrane protein kinase binding neutrophil chemotaxis regulation of peptidyl-tyrosine phosphorylation	Cell adhesion molecules (CAMs) Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Regulation of actin cytoskeleton
212981_s_at	0.396	6.630	2.278	3.759e-02	0.519	-3.797	FAM115A	family with sequence similarity 115, member A	7	-143180981	BF030508	9747	7q35	Hs.718446	6
212551_at	-0.298	11.501	-2.278	3.759e-02	0.519	-3.797	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6	17501714	NM_006366	10486	6p22.3	Hs.132902	7	actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity
208729_x_at	0.355	9.421	2.278	3.761e-02	0.519	-3.798	HLA-B	major histocompatibility complex, class I, B	6	-31429627, -2770844, -2569111	D83043	3106	6p21.3	Hs.707171 Hs.77961	1101	antigen processing and presentation of peptide antigen via MHC class I protein binding membrane fraction plasma membrane integral to plasma membrane defense response immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
218911_at	0.472	5.179	2.277	3.762e-02	0.520	-3.798	YEATS4	YEATS domain containing 4	12	68039798	NM_006530	8089	12q13-q15	Hs.4029	19	transcription factor activity structural constituent of cytoskeleton nucleus nucleoplasm mitosis protein C-terminus binding nuclear matrix chromatin modification NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation positive regulation of transcription, DNA-dependent
223170_at	0.213	5.297	2.277	3.764e-02	0.520	-3.799	TMEM98	transmembrane protein 98	17	28279040	AF132000	26022	17q11.2	Hs.3447	8	endoplasmic reticulum membrane integral to membrane
238793_at	0.371	4.670	2.277	3.765e-02	0.520	-3.799	TIGD7	tigger transposable element derived 7	16	-3288832	AI925903	91151	16p13.3	Hs.708399 Hs.718663	4	chromosome, centromeric region DNA binding mRNA binding nucleus cytoplasm ribonucleoprotein complex regulation of transcription
229487_at	0.429	5.906	2.277	3.767e-02	0.520	-3.799	EBF1	early B-cell factor 1	5	-158055500	W73890	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
209140_x_at	0.393	10.715	2.276	3.771e-02	0.520	-3.800	HLA-B	major histocompatibility complex, class I, B	6	-31429627, -2770844, -2569111	L42024	3106	6p21.3	Hs.707171 Hs.77961	1101	antigen processing and presentation of peptide antigen via MHC class I protein binding membrane fraction plasma membrane integral to plasma membrane defense response immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
211795_s_at	0.154	3.926	2.276	3.772e-02	0.520	-3.800	FYB	FYN binding protein (FYB-120/130)	5	-39141113	AF198052	2533	5p13.1	Hs.370503	27	protein binding nucleus cytoplasm protein amino acid phosphorylation NLS-bearing substrate import into nucleus immune response signal transduction protein kinase cascade
1552767_a_at	-1.146	5.544	-2.276	3.773e-02	0.520	-3.800	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	X	-131587718	NM_147174	90161	Xq26.2	Hs.385956	7	sulfotransferase activity membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
235484_at	-0.385	5.464	-2.276	3.775e-02	0.520	-3.801	PTAR1	protein prenyltransferase alpha subunit repeat containing 1	9	-71514257	BE892889	375743	9q21.12	Hs.719295	2	protein prenyltransferase activity transferase activity protein amino acid prenylation
1555797_a_at	-0.337	5.171	-2.276	3.775e-02	0.520	-3.801	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	1	-181861954	AF017807	10092	1q25.3	Hs.518609	14	actin binding structural constituent of cytoskeleton protein binding cytoplasm Arp2/3 protein complex cell motion actin cytoskeleton organization regulation of actin filament polymerization cell projection	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
213477_x_at	0.620	11.975	2.275	3.776e-02	0.520	-3.801	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	AL515273	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
208449_s_at	-0.189	5.057	-2.275	3.776e-02	0.520	-3.801	FGF8	fibroblast growth factor 8 (androgen-induced)	10	-103519876	NM_006119	2253	10q24	Hs.57710	33	extracellular region extracellular region signal transduction multicellular organismal development gastrulation growth factor activity cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
234325_at	-0.183	3.556	-2.275	3.776e-02	0.520	-3.801	C2orf65	chromosome 2 open reading frame 65	2	-74638517	Y12839	130951	2p13.1	Hs.348645	3
209960_at	0.266	2.695	2.275	3.777e-02	0.520	-3.801	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	7	-81218151, -81209942, -81169379	X16323	3082	7q21.1	Hs.396530	327	activation of MAPK activity cell morphogenesis epithelial to mesenchymal transition liver development catalytic activity serine-type endopeptidase activity protein binding extracellular region proteolysis anti-apoptosis mitosis growth factor activity platelet alpha granule lumen hepatocyte growth factor receptor signaling pathway myoblast proliferation regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Cytokine-cytokine receptor interaction Focal adhesion Pathways in cancer Renal cell carcinoma Melanoma
1557553_at	0.438	6.886	2.275	3.778e-02	0.520	-3.802	PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B	1	200584458, 200698493	BF438357	4660	1q32.1	Hs.444403	14	cytoplasm regulation of muscle contraction signal transduction enzyme activator activity	Vascular smooth muscle contraction
219334_s_at	-0.173	2.299	-2.275	3.778e-02	0.520	-3.802	OBFC2A	oligonucleotide/oligosaccharide-binding fold containing 2A	2	192251042, 192251105	NM_022837	64859	2q32.3	Hs.591610	3	nucleic acid binding nucleus
201178_at	-0.234	7.494	-2.275	3.780e-02	0.520	-3.802	FBXO7	F-box protein 7	22	31200706, 31201223	NM_012179	25793	22q12-q13	Hs.5912	19	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding ubiquitin-dependent protein catabolic process regulation of protein stability
228026_at	0.425	6.671	2.274	3.783e-02	0.520	-3.803	SIKE1	suppressor of IKBKE 1	1	-115113627	AI983535	80143	1p13.2	Hs.709277	6	cytoplasm	RIG-I-like receptor signaling pathway
222051_s_at	0.169	2.591	2.274	3.785e-02	0.520	-3.803	E2F5	E2F transcription factor 5, p130-binding	8	86276870, 86287161	AW139195	1875	8q21.2	Hs.445758	25	transcription factor activity nucleus nucleoplasm transcription factor complex cytoplasm regulation of transcription, DNA-dependent transcription factor binding organ morphogenesis	Cell cycle TGF-beta signaling pathway
204417_at	0.245	6.447	2.274	3.787e-02	0.520	-3.804	GALC	galactosylceramidase	14	-87499410, -87469110	NM_000153	2581	14q31	Hs.513439	27	galactosylceramidase activity lysosome carbohydrate metabolic process galactosylceramide catabolic process metabolic process hydrolase activity, acting on glycosyl bonds cation binding	Sphingolipid metabolism Metabolic pathways Lysosome
221417_x_at	0.192	3.960	2.274	3.789e-02	0.520	-3.804	S1PR5	sphingosine-1-phosphate receptor 5	19	-10484622	NM_030760	53637	19p13.2	Hs.501561	16	lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane	Neuroactive ligand-receptor interaction
213915_at	0.404	4.501	2.274	3.790e-02	0.520	-3.804	NKG7	natural killer cell group 7 sequence	19	-56566685	NM_005601	4818	19q13.41	Hs.10306	4	integral to plasma membrane membrane
201747_s_at	-0.272	5.752	-2.273	3.792e-02	0.521	-3.805	SAFB	scaffold attachment factor B	19	5574163	AI769566	6294	19p13.3-p13.2	Hs.23978	38	nucleotide binding DNA binding double-stranded DNA binding RNA binding protein binding nucleus nucleolus chromatin organization regulation of transcription
239710_at	0.446	4.704	2.273	3.794e-02	0.521	-3.805	FIGN	fidgetin	2	-164172363	AA993515	55137	2q24.3	Hs.593650	4	nucleotide binding ATP binding nucleoside-triphosphatase activity
229204_at	-0.364	5.855	-2.273	3.795e-02	0.521	-3.806	HP1BP3	heterochromatin protein 1, binding protein 3	1	-20941757	BE218428	50809	1p36.12	Hs.142442	3	nucleosome DNA binding nucleus chromosome nucleosome assembly
206840_at	-0.264	3.146	-2.272	3.798e-02	0.521	-3.806	AFM	afamin	4	74566325	NM_001133	173	4q11-q13	Hs.168718	19	extracellular region extracellular space transport
201275_at	0.215	7.153	2.272	3.799e-02	0.521	-3.806	FDPS	farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)	1	153545162, 153545328	NM_002004	2224	1q22	Hs.335918	30	dimethylallyltranstransferase activity geranyltranstransferase activity cytoplasm cholesterol biosynthetic process isoprenoid biosynthetic process transferase activity interspecies interaction between organisms	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
204114_at	0.341	5.841	2.272	3.800e-02	0.521	-3.807	NID2	nidogen 2 (osteonidogen)	14	-51541269	NM_007361	22795	14q21-q22	Hs.369840	15	calcium ion binding collagen binding extracellular region basement membrane cell adhesion cell-matrix adhesion bioluminescence membrane protein-chromophore linkage
238583_at	-0.438	6.923	-2.272	3.803e-02	0.521	-3.807	MSRB3	methionine sulfoxide reductase B3	12	63958754	BG023974	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
224189_x_at	-0.192	3.719	-2.272	3.804e-02	0.521	-3.808	EHF	ets homologous factor	11	34599243	AF124438	26298	11p12	Hs.653859	19	transcription factor activity protein binding nucleus multicellular organismal development cell proliferation epithelial cell differentiation sequence-specific DNA binding positive regulation of transcription, DNA-dependent
205872_x_at	-0.456	11.364	-2.272	3.805e-02	0.521	-3.808	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	NM_022359	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
227438_at	0.271	5.751	2.271	3.807e-02	0.521	-3.808	ALPK1	alpha-kinase 1	4	113437947	AI760166	80216	4q25	Hs.652825	10	protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation kinase activity transferase activity
220228_at	-0.211	2.809	-2.271	3.809e-02	0.521	-3.809	AP4E1	adaptor-related protein complex 4, epsilon 1 subunit	15	48988237	AB030653	23431	15q21.2	Hs.413366	6	structural molecule activity protein binding Golgi apparatus intracellular protein transport vesicle-mediated transport membrane coat COPI vesicle coat	Lysosome
1561927_at	0.145	2.690	2.271	3.811e-02	0.521	-3.809	C3orf16	chromosome 3 open reading frame 16	3	-150961581	AK027233	389161	3q25.1	Hs.665988	3
229414_at	-0.233	4.860	-2.270	3.815e-02	0.522	-3.810	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	17	62804385	AI676095	26207	17q24.2	Hs.591185 Hs.696160	8	protein binding intracellular cytoplasm lipid transport signal transduction lipid binding phosphatidylinositol transporter activity
221283_at	0.240	5.074	2.270	3.817e-02	0.522	-3.810	RUNX2	runt-related transcription factor 2	6	45404031, 45497891	NM_004348	860	6p21	Hs.535845	152	osteoblast differentiation transcription factor activity RNA polymerase II transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent negative regulation of transcription transcription activator activity
200681_at	-0.355	10.173	-2.270	3.818e-02	0.522	-3.811	GLO1	glyoxalase I	6	-38751679	NM_006708	2739	6p21.3-p21.1	Hs.268849	46	lactoylglutathione lyase activity cytoplasm carbohydrate metabolic process anti-apoptosis anti-apoptosis anti-apoptosis zinc ion binding lyase activity metal ion binding	Pyruvate metabolism
221814_at	0.249	4.906	2.269	3.824e-02	0.522	-3.812	GPR124	G protein-coupled receptor 124	8	37773581	BF511315	25960	8p11.23	Hs.274136	9	G-protein coupled receptor activity G-protein coupled receptor activity protein binding plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
240039_at	-0.240	4.873	-2.269	3.826e-02	0.523	-3.812	PLA2R1	phospholipase A2 receptor 1, 180kDa	2	-160510571, -160506257	T79636	22925	2q23-q24	Hs.410477	9	receptor activity binding sugar binding extracellular region extracellular space plasma membrane integral to plasma membrane endocytosis
204404_at	-0.519	5.974	-2.269	3.826e-02	0.523	-3.813	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2	5	127447381	NM_001046	6558	5q23.3	Hs.162585 Hs.712970	29	transporter activity membrane fraction integral to plasma membrane ion transport potassium ion transport sodium ion transport sodium:potassium:chloride symporter activity symporter activity membrane transepithelial chloride transport potassium ion binding sodium ion binding ammonia transporter activity transepithelial ammonium transport	Vibrio cholerae infection
231951_at	0.248	6.307	2.268	3.832e-02	0.523	-3.814	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	16	54782751, 54782751	AL512686	2775	16q13	Hs.644524	52	nucleotide binding GTPase activity signal transducer activity GTP binding intracellular muscle contraction signal transduction dopamine receptor signaling pathway locomotory behavior regulation of heart contraction cellular process guanyl nucleotide binding	Long-term depression Melanogenesis
213353_at	-0.380	7.885	-2.268	3.833e-02	0.523	-3.814	ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5	17	-64752170, -64752170	BF693921	23461	17q24.3	Hs.421474	11	nucleotide binding ATP binding lysosome endosome Golgi apparatus transport membrane integral to membrane ATPase activity	ABC transporters
223663_at	-0.189	6.376	-2.267	3.835e-02	0.523	-3.814	CCDC88B	coiled-coil domain containing 88B	11	63864270	AL136799	283234	11q12.3	Hs.98564	5
205370_x_at	0.250	9.203	2.267	3.838e-02	0.523	-3.815	DBT	dihydrolipoamide branched chain transacylase E2	1	-100425065	NM_001918	1629	1p31	Hs.709187	34	protein binding mitochondrion mitochondrial alpha-ketoglutarate dehydrogenase complex metabolic process acyltransferase activity transferase activity lipoic acid binding mitochondrial nucleoid dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity acyl-CoA biosynthetic process cofactor binding	Valine, leucine and isoleucine degradation Metabolic pathways
239482_x_at	0.234	5.646	2.267	3.838e-02	0.523	-3.815	ZNF708	zinc finger protein 708	19	-21265802	BF223715	7562	19p12	Hs.466296	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207384_at	-0.181	6.358	-2.267	3.839e-02	0.523	-3.816	PGLYRP1	peptidoglycan recognition protein 1	19	-51214280	NM_005091	8993	19q13.2-q13.3	Hs.137583	15	protein binding extracellular region bacterial binding N-acetylmuramoyl-L-alanine amidase activity peptidoglycan catabolic process peptidoglycan receptor activity detection of bacterium innate immune response defense response to Gram-positive bacterium
220087_at	-0.212	3.780	-2.266	3.844e-02	0.524	-3.817	BCMO1	beta-carotene 15,15'-monooxygenase 1	16	79829796	NM_017429	53630	16q21-q23	Hs.212172	11	beta-carotene 15,15'-monooxygenase activity iron ion binding oxidoreductase activity oxidation reduction	Retinol metabolism Metabolic pathways
221543_s_at	0.281	7.409	2.266	3.849e-02	0.524	-3.818	ERLIN2	ER lipid raft associated 2	8	37713254, 37713254, 37713356	AL442077	11160	8p11.2	Hs.705490	13	molecular_function cytoplasm endoplasmic reticulum endoplasmic reticulum membrane biological_process membrane integral to membrane
224854_s_at	0.338	6.276	2.265	3.852e-02	0.524	-3.818	SLAIN2	SLAIN motif family, member 2	4	48038369	AI979301	57606	4p11	Hs.479677	5
218962_s_at	0.199	6.525	2.265	3.855e-02	0.524	-3.819	TMEM168	transmembrane protein 168	7	-112193022	NM_022484	64418	7q31.32	Hs.709689	7	membrane integral to membrane transport vesicle
244740_at	0.714	6.242	2.264	3.857e-02	0.525	-3.819	MGC9913	hypothetical protein MGC9913	19		BE855713	386759	19q13.43	Hs.23133	1
223274_at	0.167	4.763	2.264	3.860e-02	0.525	-3.820	TCF19	transcription factor 19	6	31234281, 2577566, 2376100	BC002493	6941	6p21.3	Hs.584807	9	transcription factor activity protein binding nucleus regulation of transcription from RNA polymerase II promoter zinc ion binding cell proliferation regulation of transcription metal ion binding
209882_at	-0.267	5.477	-2.264	3.861e-02	0.525	-3.820	RIT1	Ras-like without CAAX 1	1	-154134224	AF084462	6016	1q22	Hs.491234	17	nucleotide binding calmodulin binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction small GTPase mediated signal transduction
211678_s_at	-0.326	8.537	-2.264	3.861e-02	0.525	-3.821	RNF114	ring finger protein 114	20	47986320	AF090934	55905	20q13.13	Hs.144949	9	protein binding intracellular multicellular organismal development spermatogenesis zinc ion binding cell differentiation metal ion binding
208147_s_at	0.241	2.458	2.264	3.863e-02	0.525	-3.821	CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	10	-96786518	NM_030878	1558	10q23.33	Hs.709188	97	monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	Arachidonic acid metabolism Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
208381_s_at	0.236	4.247	2.264	3.863e-02	0.525	-3.821	SGPL1	sphingosine-1-phosphate lyase 1	10	72245709	NM_003901	8879	10q21	Hs.499984	14	vasculogenesis kidney development endoplasmic reticulum lipid metabolic process ceramide metabolic process nitrogen compound metabolic process apoptosis sphinganine-1-phosphate aldolase activity post-embryonic development fibroblast migration membrane integral to membrane lyase activity carboxy-lyase activity carboxylic acid metabolic process hemopoiesis sphingolipid catabolic process pyridoxal phosphate binding integral to endoplasmic reticulum membrane regulation of multicellular organism growth platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis palate development face morphogenesis	Sphingolipid metabolism Metabolic pathways
228311_at	-0.361	6.199	-2.263	3.867e-02	0.525	-3.822	BCL6B	B-cell CLL/lymphoma 6, member B (zinc finger protein)	17	6867092	AI827455	255877	17p13.1	Hs.22575	8	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding intracellular nucleus zinc ion binding transcription repressor activity metal ion binding
216049_at	-0.275	2.824	-2.263	3.868e-02	0.525	-3.822	RHOBTB3	Rho-related BTB domain containing 3	5	95092605	AK023621	22836	5q15	Hs.445030	13	protein binding ATP binding ATPase activity Rab GTPase binding retrograde transport, endosome to Golgi
208923_at	0.388	8.287	2.263	3.869e-02	0.525	-3.822	CYFIP1	cytoplasmic FMR1 interacting protein 1	15	20444124, 20507195	BC005097	23191	15q11	Hs.26704	13	ruffle protein binding protein binding cytoplasm multicellular organismal development nervous system development regulation of cell shape synaptosome lamellipodium lamellipodium assembly cell junction cell differentiation ruffle organization synapse Rac GTPase binding perinuclear region of cytoplasm axon extension actin filament binding	Regulation of actin cytoskeleton
209303_at	0.276	10.252	2.263	3.869e-02	0.525	-3.822	NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	5	52892221	BC005270	4724	5q11.1	Hs.528222	28	regulation of protein amino acid phosphorylation mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport brain development NADH dehydrogenase (ubiquinone) activity membrane oxidoreductase activity, acting on NADH or NADPH cAMP-mediated signaling electron transport chain mitochondrial respiratory chain complex I assembly cellular respiration positive regulation of fibroblast proliferation response to cAMP respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
219811_at	0.212	6.849	2.263	3.870e-02	0.525	-3.823	DGCR8	DiGeorge syndrome critical region gene 8	22	18447833	NM_022720	54487	22q11.2	Hs.643452 Hs.713579	21	double-stranded RNA binding protein binding intracellular nucleus cytoplasm primary microRNA processing
233169_at	0.180	3.693	2.263	3.871e-02	0.525	-3.823	ZNF350	zinc finger protein 350	19	-57159404	AU145915	59348	19q13.41	Hs.407694	23	DNA binding protein binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding nuclear matrix negative regulation of transcription transcription repressor activity transcriptional repressor complex metal ion binding
204984_at	-0.456	7.219	-2.262	3.874e-02	0.525	-3.823	GPC4	glypican 4	X	-132262729	NM_001448	2239	Xq26.1	Hs.58367	12	extracellular region proteinaceous extracellular matrix extracellular space plasma membrane integral to plasma membrane cell proliferation anatomical structure morphogenesis anchored to membrane heparan sulfate proteoglycan binding
205944_s_at	0.244	7.683	2.262	3.879e-02	0.525	-3.824	CLTCL1	clathrin, heavy chain-like 1	22	-17546988	NM_007098	8218	22q11.2 22q11.21	Hs.368266	15	signal transducer activity structural molecule activity protein binding intracellular protein transport receptor-mediated endocytosis anatomical structure morphogenesis membrane vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle	Lysosome Endocytosis Huntington's disease
225605_at	-0.214	6.481	-2.261	3.880e-02	0.525	-3.825	TP53I13	tumor protein p53 inducible protein 13	17	24919864	AL540867	90313	17q11.2	Hs.514050	4	cytoplasm plasma membrane integral to membrane
234687_x_at	0.199	6.971	2.261	3.880e-02	0.525	-3.825	LIMD1	LIM domains containing 1	3	45611326	M80651	8994	3p21.3	Hs.193370 Hs.621057	14	protein binding regulation of transcription, DNA-dependent signal transduction multicellular organismal development zinc ion binding metal ion binding
201989_s_at	-0.219	6.877	-2.261	3.882e-02	0.525	-3.825	CREBL2	cAMP responsive element binding protein-like 2	12	12656097	AL529409	1389	12p13	Hs.591156	5	transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle signal transduction sequence-specific DNA binding protein dimerization activity
228556_at	-0.211	6.124	-2.261	3.883e-02	0.525	-3.825	YTHDC1	YTH domain containing 1	4	-68858699	AI990739	91746	4q13.2	Hs.175955	18	nucleus mRNA processing RNA splicing
205956_x_at	0.231	6.369	2.261	3.885e-02	0.526	-3.826	PSMC3IP	PSMC3 interacting protein	17	-37977854	NM_013290	29893	17q12-q21	Hs.383019	9	molecular_function DNA binding protein binding cellular_component nucleus DNA recombination meiosis biological_process
1559759_at	0.219	4.305	2.260	3.889e-02	0.526	-3.827	KIFC3	kinesin family member C3	16	-56349629, -56349629	BE407830	3801	16q13-q21	Hs.23131	10	nucleotide binding microtubule motor activity ATP binding Golgi apparatus kinesin complex microtubule microtubule-based movement Golgi organization visual perception
220401_at	0.219	2.457	2.260	3.889e-02	0.526	-3.827	FLJ21369	hypothetical protein FLJ21369	19		NM_024802	79860	19q13.11	Hs.529098
1569032_at	0.212	4.074	2.259	3.895e-02	0.526	-3.828	LOC642852	hypothetical LOC642852	21	45532394	BC033767	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
238994_at	-0.292	5.652	-2.259	3.897e-02	0.526	-3.829	OTUD7B	OTU domain containing 7B	1	-148178855	AW022496	56957	1q21.2	Hs.98322	11	DNA binding ubiquitin thiolesterase activity protein binding nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding protein deubiquitination modification-dependent protein catabolic process negative regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
200989_at	0.322	7.856	2.259	3.900e-02	0.526	-3.829	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	61231871	NM_001530	3091	14q21-q24	Hs.597216	743	response to hypoxia neural crest cell migration epithelial to mesenchymal transition embryonic placenta development positive regulation of endothelial cell proliferation heart looping connective tissue replacement during inflammatory response RNA polymerase II transcription factor activity, enhancer binding signal transducer activity nucleus transcription factor complex nucleolus cytoplasm lactate metabolic process regulation of transcription, DNA-dependent cellular iron ion homeostasis signal transduction transcription factor binding microtubule-based flagellum positive regulation vascular endothelial growth factor production positive regulation of epithelial cell migration response to muscle activity cell differentiation positive regulation of vascular endothelial growth factor receptor signaling pathway oxygen homeostasis positive regulation of chemokine production regulation of transforming growth factor-beta2 production collagen metabolic process histone acetyltransferase binding embryonic hemopoiesis hemoglobin biosynthetic process glucose homeostasis mRNA transcription from RNA polymerase II promoter regulation of apoptosis positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of angiogenesis positive regulation of glycolysis negative regulation of growth positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter muscle maintenance positive regulation of hormone biosynthetic process protein heterodimerization activity protein heterodimerization activity regulation of catalytic activity positive regulation of nitric-oxide synthase activity cartilage development elastin metabolic process Hsp90 protein binding	mTOR signaling pathway Pathways in cancer Renal cell carcinoma
209036_s_at	0.183	12.037	2.259	3.901e-02	0.526	-3.829	MDH2	malate dehydrogenase 2, NAD (mitochondrial)	7	75515328	BC001917	4191	7cen-q22	Hs.520967	26	binding mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix glycolysis tricarboxylic acid cycle malate metabolic process malate metabolic process oxidoreductase activity L-malate dehydrogenase activity L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
207250_at	-0.179	3.737	-2.259	3.901e-02	0.526	-3.829	SIX6	SIX homeobox 6	14	60045690	NM_007374	4990	14q22.3-q23	Hs.194756	10	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development visual perception organ morphogenesis sequence-specific DNA binding
225138_at	-0.387	7.678	-2.259	3.902e-02	0.526	-3.829	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	N52625	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
209410_s_at	-1.131	7.105	-2.258	3.902e-02	0.526	-3.829	GRB10	growth factor receptor-bound protein 10	7	-50625253, -50625253, -50625253	AF000017	2887	7p12-p11.2	Hs.164060	51	SH3/SH2 adaptor activity insulin receptor binding protein binding cytoplasm plasma membrane signal transduction cell-cell signaling negative regulation of glucose import negative regulation of insulin receptor signaling pathway
1564112_at	0.179	6.060	2.258	3.908e-02	0.527	-3.831	FAM71A	family with sequence similarity 71, member A	1	210864438	AK097437	149647	1q32.3	Hs.129293	4
1562239_at	0.255	4.648	2.258	3.909e-02	0.527	-3.831	SGSM1	small G protein signaling modulator 1	22	23532135	AB075821	129049	22q11.23	Hs.474397 Hs.620906	5	Rab GTPase activator activity intracellular Golgi apparatus regulation of Rab GTPase activity
212549_at	-0.346	7.854	-2.257	3.910e-02	0.527	-3.831	STAT5B	signal transducer and activator of transcription 5B	17	-37604720	BE645861	6777	17q11.2	Hs.719121	128	allantoin metabolic process luteinization natural killer cell differentiation transcription factor activity signal transducer activity calcium ion binding protein binding nucleus cytoplasm citrate metabolic process 2-oxoglutarate metabolic process succinate metabolic process oxaloacetate metabolic process isoleucine metabolic process valine metabolic process creatine metabolic process fatty acid metabolic process signal transduction female pregnancy lactation positive regulation of cell proliferation regulation of steroid metabolic process cytokine-mediated signaling pathway taurine metabolic process lipid storage regulation of cell adhesion regulation of epithelial cell differentiation response to estradiol stimulus cellular response to hormone stimulus T cell differentiation in the thymus glucocorticoid receptor binding positive regulation of multicellular organism growth positive regulation of activated T cell proliferation progesterone metabolic process T cell homeostasis negative regulation of apoptosis positive regulation of interleukin-2 biosynthetic process positive regulation of B cell differentiation positive regulation of gamma-delta T cell differentiation negative regulation of erythrocyte differentiation positive regulation of survival gene product expression positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter creatinine metabolic process development of secondary female sexual characteristics development of secondary male sexual characteristics Peyer's patch development positive regulation of inflammatory response JAK-STAT cascade involved in growth hormone signaling pathway	ErbB signaling pathway Chemokine signaling pathway Jak-STAT signaling pathway Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia
1552785_at	0.240	2.742	2.257	3.910e-02	0.527	-3.831	ZNF781	zinc finger protein 781	19	-42850489	NM_152605	163115	19q13.12	Hs.116622	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
244587_at	0.185	6.545	2.257	3.913e-02	0.527	-3.832	ATF7	activating transcription factor 7	12	-52192109, -52192109	AA534039	11016	12q13	Hs.12286	18	transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding protein dimerization activity
225142_at	-0.310	4.285	-2.257	3.913e-02	0.527	-3.832	JHDM1D	jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)	7	-139431014	AW294022	80853	7q34	Hs.308710	3	protein binding zinc ion binding metal ion binding
219178_at	0.280	3.635	2.257	3.915e-02	0.527	-3.832	QTRTD1	queuine tRNA-ribosyltransferase domain containing 1	3	115258300	NM_024638	79691	3q13.31	Hs.477162	2	mitochondrion zinc ion binding queuine tRNA-ribosyltransferase activity queuosine biosynthetic process transferase activity, transferring glycosyl groups metal ion binding
218468_s_at	-0.498	3.415	-2.257	3.915e-02	0.527	-3.832	GREM1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	15	30797496	AF154054	26585	15q13-q15	Hs.40098	28	cytokine activity protein binding extracellular region extracellular space multicellular organismal development nervous system development
223629_at	-0.298	4.087	-2.256	3.919e-02	0.527	-3.833	PCDHB5	protocadherin beta 5	5	140494983	BC001186	26167	5q31	Hs.119693	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion synaptic transmission synaptogenesis integral to membrane calcium-dependent cell-cell adhesion
219115_s_at	0.314	2.752	2.256	3.924e-02	0.527	-3.834	IL20RA	interleukin 20 receptor, alpha	6	-137362800	NM_014432	53832	6q22.33-q23.1	Hs.445868	15	receptor activity cytokine receptor activity membrane integral to membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
221022_s_at	0.170	5.485	2.255	3.924e-02	0.527	-3.834	PMFBP1	polyamine modulated factor 1 binding protein 1	16	-70710497, -70710497	NM_031293	83449	16q22.2	Hs.714939	10	cytoplasm
209695_at	0.371	9.858	2.255	3.927e-02	0.527	-3.835	PTP4A3	protein tyrosine phosphatase type IVA, member 3	8	142501188	BC003105	11156	8q24.3	Hs.43666	45	prenylated protein tyrosine phosphatase activity early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity identical protein binding
205164_at	0.263	6.977	2.255	3.927e-02	0.527	-3.835	GCAT	glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)	22	36533900	NM_014291	23464	22q13.1	Hs.54609	6	mitochondrion mitochondrial inner membrane cellular amino acid metabolic process acyltransferase activity glycine C-acetyltransferase activity biosynthetic process transferase activity, transferring nitrogenous groups pyridoxal phosphate binding	Glycine, serine and threonine metabolism
209746_s_at	-0.210	7.095	-2.255	3.927e-02	0.527	-3.835	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	16	18986427	AF032900	10229	16p13.11-p12.3	Hs.157113	18	iron ion binding nucleus mitochondrion ubiquinone biosynthetic process oxidoreductase activity protein metabolic process	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
206218_at	-0.264	3.697	-2.255	3.930e-02	0.527	-3.836	MAGEB2	melanoma antigen family B, 2	X	30143595	NM_002364	4113	Xp21.3	Hs.113824	12	protein binding
225044_at	0.255	7.299	2.255	3.931e-02	0.527	-3.836	NT5C3L	5'-nucleotidase, cytosolic III-like	17	-37234948	AL526783	115024	17q21.2	Hs.237536	1	nucleotide binding magnesium ion binding cytoplasm 5'-nucleotidase activity nucleotide metabolic process transferase activity hydrolase activity
225578_at	-0.436	7.671	-2.255	3.931e-02	0.527	-3.836	C13orf37	chromosome 13 open reading frame 37	13	-72180495	AI885466	440145	13q21.33-q22.1	Hs.28465	1
210038_at	-0.395	10.013	-2.255	3.931e-02	0.527	-3.836	PRKCQ	protein kinase C, theta	10	-6509110	AL137145	5588	10p15	Hs.498570	112	nucleotide binding magnesium ion binding regulation of cell growth protein kinase C activity protein binding ATP binding intracellular protein amino acid phosphorylation membrane protein ectodomain proteolysis intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding	Vascular smooth muscle contraction Tight junction T cell receptor signaling pathway Adipocytokine signaling pathway
211937_at	-0.196	8.042	-2.254	3.933e-02	0.527	-3.836	EIF4B	eukaryotic translation initiation factor 4B	12	51686328	NM_001417	1975	12q13.13	Hs.648394 Hs.702041	23	nucleotide binding RNA binding translation initiation factor activity cytosol translation regulation of translational initiation eukaryotic translation initiation factor 4F complex	mTOR signaling pathway
228984_at	0.411	8.080	2.254	3.934e-02	0.527	-3.837	ATPGD1	ATP-grasp domain containing 1	11	66939724	AB037815	57571	11q13.2	Hs.502982	3	nucleotide binding catalytic activity ATP binding manganese ion binding metal ion binding
212523_s_at	0.223	3.874	2.254	3.934e-02	0.527	-3.837	KIAA0146	KIAA0146	8	48336094	D63480	23514	8q11.21	Hs.381058	6
231481_at	0.206	3.937	2.254	3.935e-02	0.527	-3.837	CCNB3	cyclin B3	X	50044279	AI003521	85417	Xp11	Hs.130310	17	nucleus nucleolus cell cycle meiosis cell division	Cell cycle p53 signaling pathway
219525_at	-0.247	8.074	-2.254	3.935e-02	0.527	-3.837	SLC47A1	solute carrier family 47, member 1	17	19377758	NM_018242	55244	17p11.2	Hs.232054	16	plasma membrane transport multidrug transport drug transporter activity antiporter activity integral to membrane
202100_at	-0.384	7.047	-2.254	3.936e-02	0.527	-3.837	RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	2	120726883	BG169673	5899	2cen-q13	Hs.469820	23	nucleotide binding protein binding GTP binding intracellular plasma membrane Ras protein signal transduction	Pathways in cancer Pancreatic cancer
213750_at	-0.236	8.432	-2.254	3.939e-02	0.527	-3.838	RSL1D1	ribosomal L1 domain containing 1	16	-11835555	AA928506	26156	16p13.13	Hs.401842	17	RNA binding structural constituent of ribosome protein binding intracellular nucleus nucleolus ribosome RNA processing translation regulation of protein localization
1554544_a_at	-0.409	7.086	-2.253	3.940e-02	0.527	-3.838	MBP	myelin basic protein	18	-72853726, -72819776, -72819776	L18865	4155	18q23	Hs.551713	102	plasma membrane immune response synaptic transmission central nervous system development structural constituent of myelin sheath internode region of axon myelination cell projection cell soma myelin sheath
226897_s_at	-0.368	5.631	-2.253	3.941e-02	0.527	-3.838	ZC3H7A	zinc finger CCCH-type containing 7A	16	-11751942	AW169959	29066	16p13-p12	Hs.371856	5	nucleic acid binding intracellular nucleus zinc ion binding metal ion binding
226474_at	0.307	5.782	2.253	3.944e-02	0.527	-3.839	NLRC5	NLR family, CARD domain containing 5	16	55580910	AA005023	84166	16q13	Hs.528836	3	nucleotide binding protein binding ATP binding cytoplasm
221476_s_at	-0.314	10.485	-2.253	3.945e-02	0.527	-3.839	RPL15	ribosomal protein L15	3	23933642	AF279903	6138	3p24.2	Hs.381219 Hs.695621	14	RNA binding structural constituent of ribosome intracellular cytosol ribosome translational elongation	Ribosome
1568680_s_at	0.374	6.800	2.253	3.947e-02	0.527	-3.839	YTHDC2	YTH domain containing 2	5	112877308	BC019100	64848	5q22.2	Hs.231942	6	nucleotide binding nucleic acid binding helicase activity ATP binding hydrolase activity
231114_at	0.419	2.627	2.252	3.952e-02	0.527	-3.840	SPATA22	spermatogenesis associated 22	17	-3290063	BF438413	84690	17p13.3	Hs.351068	3
230925_at	0.376	4.932	2.252	3.952e-02	0.527	-3.841	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	10	26767271	AI093231	54518	10p12.1	Hs.310421	9	cytoplasm cytoskeleton plasma membrane focal adhesion signal transduction lamellipodium cell junction
232138_at	0.429	6.634	2.252	3.953e-02	0.527	-3.841	MBNL2	muscleblind-like 2 (Drosophila)	13	96672574	AW276914	10150	13q32.1	Hs.657347	9	RNA binding nucleus cytoplasm zinc ion binding metal ion binding
65635_at	0.208	7.621	2.252	3.954e-02	0.527	-3.841	ENGASE	endo-beta-N-acetylglucosaminidase	17	74582613	AL044097	64772	17q25.3	Hs.29288	5	intracellular cytoplasm cytosol metabolic process hydrolase activity, acting on glycosyl bonds mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	Other glycan degradation
210774_s_at	-0.266	10.935	-2.252	3.954e-02	0.527	-3.841	NCOA4	nuclear receptor coactivator 4	10	51235113, 51242369, 51246290	AL162047	8031	10q11.2	Hs.643658 Hs.709644	43	transcription coactivator activity protein binding nucleus male gonad development androgen receptor signaling pathway regulation of transcription positive regulation of transcription, DNA-dependent androgen receptor binding	Pathways in cancer Thyroid cancer
201496_x_at	-0.482	5.813	-2.251	3.955e-02	0.527	-3.841	MYH11	myosin, heavy chain 11, smooth muscle	16	-15704492	S67238	4629	16p13.11	Hs.460109	33	nucleotide binding motor activity actin binding calmodulin binding ATP binding striated muscle thick filament smooth muscle contraction striated muscle contraction structural constituent of muscle myosin complex muscle thick filament assembly melanosome elastic fiber assembly cardiac muscle fiber development	Vascular smooth muscle contraction Tight junction
201861_s_at	0.274	6.906	2.251	3.955e-02	0.527	-3.841	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2	238200962, 238265545, 238265545	BF965566	9208	2q37.3	Hs.471779	16	DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity
218309_at	0.230	7.017	2.251	3.955e-02	0.527	-3.841	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	1	-20681470	NM_018584	55450	1p36.12	Hs.197922	4	plasma membrane calcium-dependent protein kinase inhibitor activity postsynaptic density synaptosome protein kinase binding cell junction dendrite cell soma synapse postsynaptic membrane
219237_s_at	0.244	6.182	2.251	3.957e-02	0.528	-3.842	DNAJB14	DnaJ (Hsp40) homolog, subfamily B, member 14	4	-101039734	NM_024920	79982	4q23	Hs.577426	6	protein folding membrane integral to membrane heat shock protein binding unfolded protein binding
1557094_at	-0.199	3.664	-2.251	3.959e-02	0.528	-3.842	LOC653110	hypothetical LOC653110	10		BC029890	653110	10q11.22		2
1556134_a_at	-0.553	7.294	-2.249	3.970e-02	0.529	-3.844	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	3	184453725	BC013229	84002	3q28	Hs.718506	7	intracellular Golgi apparatus protein amino acid glycosylation multicellular organismal development central nervous system development galactosyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity lipopolysaccharide N-acetylglucosaminyltransferase activity glycolipid biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
209505_at	-0.238	2.644	-2.249	3.970e-02	0.529	-3.844	NR2F1	nuclear receptor subfamily 2, group F, member 1	5	92944798	AI951185	7025	5q14	Hs.519445	28	negative regulation of transcription from RNA polymerase II promoter neuron migration transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription coactivator activity nucleus regulation of transcription, DNA-dependent signal transduction nervous system development zinc ion binding forebrain development sequence-specific DNA binding metal ion binding
212428_at	-0.363	9.043	-2.249	3.970e-02	0.529	-3.845	KIAA0368	KIAA0368	9	-113162793	AW001101	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
244710_at	-0.387	3.990	-2.249	3.972e-02	0.529	-3.845	LRGUK	leucine-rich repeats and guanylate kinase domain containing	7	133462644	BE044261	136332	7q33	Hs.149774	4	nucleotide binding protein binding ATP binding kinase activity transferase activity
241710_at	0.334	3.914	2.249	3.973e-02	0.529	-3.845	hCG_1645220	hCG1645220	2	-43755795	AI436290	728819	2p21	Hs.602756	1
204293_at	0.282	4.950	2.249	3.976e-02	0.529	-3.846	SGSH	N-sulfoglucosamine sulfohydrolase	17	-75797673	NM_000199	6448	17q25.3	Hs.31074	25	calcium ion binding protein binding lysosome proteoglycan metabolic process metabolic process sulfuric ester hydrolase activity N-sulfoglucosamine sulfohydrolase activity hydrolase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
227647_at	0.291	5.891	2.249	3.978e-02	0.529	-3.846	KCNE3	potassium voltage-gated channel, Isk-related family, member 3	11	-73843533	AI692703	10008	11q13-q14	Hs.523899	24	voltage-gated ion channel activity voltage-gated potassium channel activity ion transport potassium ion transport membrane integral to membrane potassium ion binding
236314_at	0.267	5.271	2.248	3.978e-02	0.529	-3.846	EPM2AIP1	EPM2A (laforin) interacting protein 1	3	-37002361	AW162758	9852	3p22.1	Hs.28020	8	endoplasmic reticulum
213614_x_at	0.705	11.708	2.248	3.979e-02	0.529	-3.846	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	BE786672	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
215605_at	0.246	5.076	2.248	3.983e-02	0.529	-3.847	NCOA2	nuclear receptor coactivator 2	8	-71186820	AU145806	10499	8q13.3	Hs.446678	89	negative regulation of transcription from RNA polymerase II promoter signal transducer activity receptor binding nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription repressor activity thyroid hormone receptor coactivator activity steroid hormone receptor signaling pathway nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter
220660_at	-0.264	3.029	-2.248	3.984e-02	0.529	-3.847	C9orf27	chromosome 9 open reading frame 27	9	-117690364	NM_021208	58483	9q31.3	Hs.23367	2	molecular_function cellular_component biological_process
1557331_at	-0.196	4.699	-2.247	3.986e-02	0.529	-3.848	POLR1B	polymerase (RNA) I polypeptide B, 128kDa	2	113015962	CA442932	84172	2q13	Hs.86337	21	DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm nucleolus transcription zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
206748_s_at	-0.201	4.397	-2.247	3.990e-02	0.530	-3.849	SPAG9	sperm associated antigen 9	17	-46394534	NM_003971	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
201723_s_at	-0.357	8.049	-2.247	3.991e-02	0.530	-3.849	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	U41514	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
232253_at	0.288	6.864	2.246	3.995e-02	0.530	-3.850	C5orf56	chromosome 5 open reading frame 56	5	131774571	AL564637	441108	5q31.1	Hs.658288	1
1559618_at	0.180	3.406	2.246	3.996e-02	0.530	-3.850	LOC100129447	hypothetical protein LOC100129447	12		BQ188678	100129447	12q24.13	Hs.661564	1
207335_x_at	0.257	10.749	2.246	3.997e-02	0.530	-3.850	ATP5I	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	4	-656224	NM_007100	521	4p16.3	Hs.85539	14	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
230742_at	0.367	4.054	2.246	3.998e-02	0.530	-3.850	RBM6	RNA binding motif protein 6	3	49952595	AA742596	10180	3p21.3	Hs.439480	12	DNA binding RNA binding intracellular nucleus RNA processing zinc ion binding
208328_s_at	0.282	7.297	2.246	3.999e-02	0.530	-3.851	MEF2A	myocyte enhancer factor 2A	15	97923655, 97990705	NM_005587	4205	15q26	Hs.268675	77	transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding
211399_at	-0.190	4.849	-2.246	3.999e-02	0.530	-3.851	FGFR2	fibroblast growth factor receptor 2	10	-123231358, -123231358, -123227834, -123227834, -123227834, -123227834, -123227833	AB030077	2263	10q26	Hs.533683	232	nucleotide binding receptor activity fibroblast growth factor receptor activity protein binding ATP binding extracellular region plasma membrane plasma membrane protein amino acid phosphorylation heparin binding fibroblast growth factor receptor signaling pathway cell surface integral to membrane cell growth transferase activity	MAPK signaling pathway Endocytosis Regulation of actin cytoskeleton Pathways in cancer Prostate cancer
230981_at	0.276	5.164	2.246	3.999e-02	0.530	-3.851	CATSPER3	cation channel, sperm associated 3	5	134331512	AI219834	347732	5q31.1	Hs.631804	6	ciliary or flagellar motility acrosomal vesicle calcium activated cation channel activity voltage-gated ion channel activity calcium channel activity calcium ion binding protein binding endoplasmic reticulum plasma membrane cilium ion transport sodium ion transport calcium ion transport multicellular organismal development spermatogenesis integral to membrane flagellum cell differentiation sperm motility
202059_s_at	-0.370	7.441	-2.246	4.000e-02	0.530	-3.851	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	NM_002264	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
202050_s_at	-0.222	7.009	-2.245	4.008e-02	0.530	-3.853	ZMYM4	zinc finger, MYM-type 4	1	35507154	AI650586	9202	1p32-p34	Hs.269211	7	DNA binding nucleus multicellular organismal development zinc ion binding metal ion binding
231845_at	0.168	5.932	2.244	4.008e-02	0.530	-3.853	AARS2	alanyl-tRNA synthetase 2, mitochondrial (putative)	6	-44374440	AI721172	57505	6p21.1	Hs.158381	7	nucleotide binding nucleic acid binding alanine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix translation alanyl-tRNA aminoacylation ligase activity tRNA aminoacylation	Aminoacyl-tRNA biosynthesis
225377_at	0.405	7.538	2.244	4.009e-02	0.530	-3.853	C9orf86	chromosome 9 open reading frame 86	9	138822201	BE783949	55684	9q34.3	Hs.370555	11	nucleotide binding protein binding GTP binding nucleus cytoplasm small GTPase mediated signal transduction
214329_x_at	0.756	7.124	2.244	4.012e-02	0.531	-3.854	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	3	-173706157	AW474434	8743	3q26	Hs.478275	343	cytokine activity tumor necrosis factor receptor binding extracellular region extracellular space soluble fraction integral to plasma membrane induction of apoptosis immune response signal transduction cell-cell signaling zinc ion binding activation of pro-apoptotic gene products membrane positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity
214395_x_at	-0.276	5.974	-2.244	4.015e-02	0.531	-3.854	EEF1D	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	8	-144733040, -144733040	AI335509	1936	8q24.3	Hs.333388 Hs.686554	42	translation elongation factor activity signal transducer activity protein binding cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation positive regulation of I-kappaB kinase/NF-kappaB cascade
209696_at	0.224	4.851	2.244	4.015e-02	0.531	-3.854	FBP1	fructose-1,6-bisphosphatase 1	9	-96405237, -96405237	D26054	2203	9q22.3	Hs.494496	31	magnesium ion binding fructose-2,6-bisphosphate 2-phosphatase activity cytosol carbohydrate metabolic process fructose metabolic process gluconeogenesis hydrolase activity fructose 1,6-bisphosphate 1-phosphatase activity fructose 1,6-bisphosphate 1-phosphatase activity phosphoric ester hydrolase activity identical protein binding	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Metabolic pathways Insulin signaling pathway
212263_at	0.346	9.746	2.243	4.017e-02	0.531	-3.854	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	AI114716	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
226599_at	0.242	5.277	2.243	4.017e-02	0.531	-3.854	FHDC1	FH2 domain containing 1	4	154083584	AA527080	85462	4q31.3	Hs.132629	5	actin binding cellular component organization actin cytoskeleton organization
222357_at	-0.415	6.839	-2.243	4.021e-02	0.531	-3.855	ZBTB20	zinc finger and BTB domain containing 20	3	-115540212	AW974823	26137	3q13.2	Hs.655108	13	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
217824_at	-0.265	5.019	-2.243	4.021e-02	0.531	-3.856	UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)	6	-90093062	AW500009	51465	6q15	Hs.163776	12	nucleotide binding ubiquitin-protein ligase activity ATP binding endoplasmic reticulum membrane integral to membrane ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
227577_at	-0.429	6.640	-2.243	4.021e-02	0.531	-3.856	EXOC8	exocyst complex component 8	1	-229535104	AI168350	149371	1q42.2	Hs.356198	11	protein binding cytoplasm exocytosis protein transport growth cone cell projection
213461_at	-0.348	3.270	-2.243	4.022e-02	0.531	-3.856	NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	16	-55020548	AI800983	11051	16q12.2	Hs.528834	26	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus centrosome hydrolase activity paraspeckles
204089_x_at	0.258	7.771	2.243	4.023e-02	0.531	-3.856	MAP3K4	mitogen-activated protein kinase kinase kinase 4	6	161332811	NM_006724	4216	6q26	Hs.390428	20	nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding response to stress JNK cascade transferase activity	MAPK signaling pathway GnRH signaling pathway
1553863_at	0.189	3.056	2.242	4.024e-02	0.531	-3.856	WDFY4	WDFY family member 4	10	49563523	NM_173524	57705	10q11.22-q11.23	Hs.287379	8	binding membrane integral to membrane
201947_s_at	-0.305	8.984	-2.242	4.024e-02	0.531	-3.856	CCT2	chaperonin containing TCP1, subunit 2 (beta)	12	68265474	NM_006431	10576	12q15	Hs.189772	19	nucleotide binding ATP binding nucleus nucleolus cytoplasm cytosol chaperonin-containing T-complex protein folding unfolded protein binding
214356_s_at	-0.227	9.260	-2.242	4.029e-02	0.531	-3.857	KIAA0368	KIAA0368	9	-113162793	AI272899	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
244353_s_at	0.346	6.558	2.241	4.034e-02	0.531	-3.858	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12	6	-134350411	AI675682	154091	6q23.2	Hs.486508	11	transporter activity cytoplasm carbohydrate transport membrane integral to membrane substrate-specific transmembrane transporter activity perinuclear region of cytoplasm transmembrane transport
222187_x_at	-0.434	6.627	-2.241	4.034e-02	0.531	-3.858	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	X78262	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
211844_s_at	-0.191	2.626	-2.241	4.038e-02	0.531	-3.859	NRP2	neuropilin 2	2	206255468, 206255468, 206255468	AF022859	8828	2q33.3	Hs.471200	44	receptor activity vascular endothelial growth factor receptor activity membrane fraction plasma membrane cell adhesion multicellular organismal development nervous system development axon guidance integral to membrane cell differentiation
228323_at	-0.362	3.685	-2.241	4.039e-02	0.531	-3.859	CASC5	cancer susceptibility candidate 5	15	38673738	BF248364	57082	15q14	Hs.181855	16	acrosomal vesicle acrosome assembly protein binding nucleus
222292_at	0.174	3.560	2.240	4.041e-02	0.531	-3.860	CD40	CD40 molecule, TNF receptor superfamily member 5	20	44180312	AW298127	958	20q12-q13.2	Hs.472860	290	receptor activity extracellular region plasma membrane plasma membrane integral to plasma membrane protein complex assembly inflammatory response enzyme binding platelet activation B cell proliferation positive regulation of I-kappaB kinase/NF-kappaB cascade	Cytokine-cytokine receptor interaction Cell adhesion molecules (CAMs) Toll-like receptor signaling pathway Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Primary immunodeficiency
211220_s_at	-0.712	4.581	-2.240	4.042e-02	0.531	-3.860	HSF2	heat shock transcription factor 2	6	122762394	BC005329	3298	6q22.31	Hs.158195	28	transcription factor activity transcription coactivator activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress spermatogenesis protein homodimerization activity sequence-specific DNA binding
1561434_at	0.233	3.507	2.240	4.046e-02	0.531	-3.861	C15orf45	chromosome 15 open reading frame 45	15		AI956139	641318	15q13.3	Hs.711585	2
202854_at	0.453	7.888	2.240	4.047e-02	0.531	-3.861	HPRT1	hypoxanthine phosphoribosyltransferase 1	X	133421840	NM_000194	3251	Xq26.1	Hs.412707	104	magnesium ion binding response to amphetamine purine binding hypoxanthine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity soluble fraction cytoplasm cytosol purine nucleotide biosynthetic process purine ribonucleoside salvage adenine salvage guanine salvage grooming behavior nucleoside metabolic process transferase activity, transferring glycosyl groups cytolysis striatum development cerebral cortex neuron differentiation central nervous system neuron development protein homodimerization activity positive regulation of dopamine metabolic process hypoxanthine metabolic process lymphocyte proliferation dendrite morphogenesis protein homotetramerization	Purine metabolism Drug metabolism - other enzymes Metabolic pathways
203327_at	-0.294	8.398	-2.240	4.047e-02	0.531	-3.861	IDE	insulin-degrading enzyme	10	-94203579	N22903	3416	10q23-q25	Hs.500546	94	metalloendopeptidase activity signal transducer activity ATP binding extracellular space soluble fraction cytoplasm peroxisome proteolysis signal transduction sex differentiation peptidase activity zinc ion binding bradykinin catabolic process protein homodimerization activity metal ion binding beta-amyloid metabolic process	Alzheimer's disease
238039_at	0.246	4.326	2.239	4.047e-02	0.531	-3.861	LOC728769	hypothetical protein LOC728769	5		BG180437	728769	5q14.1	Hs.586193
231815_at	0.376	5.695	2.239	4.049e-02	0.531	-3.861	PHF12	PHD finger protein 12	17	-24263287, -24256396	AB040956	57649	17q11.2	Hs.714975	9	protein binding nucleus nucleolus zinc ion binding transcription repressor activity transcriptional repressor complex regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding
225398_at	-0.385	9.382	-2.239	4.050e-02	0.531	-3.862	RPUSD4	RNA pseudouridylate synthase domain containing 4	11	-125577199	AL580514	84881	11q24.2	Hs.150458	5	pseudouridine synthesis RNA binding pseudouridine synthase activity
205633_s_at	0.689	8.371	2.239	4.050e-02	0.531	-3.862	ALAS1	aminolevulinate, delta-, synthase 1	3	52207155, 52207183	NM_000688	211	3p21.1	Hs.476308	24	5-aminolevulinate synthase activity mitochondrion mitochondrial matrix heme biosynthetic process acyltransferase activity transferase activity, transferring nitrogenous groups pyridoxal phosphate binding tetrapyrrole biosynthetic process	Glycine, serine and threonine metabolism Porphyrin and chlorophyll metabolism Metabolic pathways
216526_x_at	0.410	9.841	2.239	4.052e-02	0.531	-3.862	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	AK024836	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
229089_at	0.219	5.952	2.239	4.053e-02	0.531	-3.862	ZNF509	zinc finger protein 509	4	4342824	BF061904	166793	4p16.3	Hs.419997	3	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
239890_s_at	0.250	2.703	2.239	4.054e-02	0.531	-3.862	SERP2	stress-associated endoplasmic reticulum protein family member 2	13	43845977	BG054503	387923	13q14.11	Hs.377972	4	endoplasmic reticulum protein transport membrane integral to membrane intracellular protein transmembrane transport
205134_s_at	0.354	5.321	2.238	4.060e-02	0.531	-3.864	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	13	-44411383	AW593143	26747	13q14	Hs.525006	11	box C/D snoRNP assembly DNA binding intracellular nucleus perichromatin fibrils nucleolus RNA processing transcription elongation factor complex zinc ion binding nuclear matrix cytosolic ribosome snoRNA binding protein binding, bridging identical protein binding positive regulation of transcription from RNA polymerase II promoter metal ion binding presynaptic active zone pre-snoRNP complex
208400_at	-0.180	3.455	-2.237	4.064e-02	0.531	-3.864	GLP1R	glucagon-like peptide 1 receptor	6	39124534	U01157	2740	6p21	Hs.389103	31	glucagon receptor activity plasma membrane response to stress G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity elevation of cytosolic calcium ion concentration learning or memory regulation of heart contraction peptide receptor activity, G-protein coupled integral to membrane cAMP-mediated signaling insulin secretion hormone secretion	Neuroactive ligand-receptor interaction
224827_at	-0.367	6.243	-2.237	4.064e-02	0.531	-3.865	UBTD2	ubiquitin domain containing 2	5	-171569254	AK022894	92181	5q35.1	Hs.131570 Hs.716824	7	cytoplasm
212403_at	-0.294	7.503	-2.237	4.064e-02	0.531	-3.865	UBE3B	ubiquitin protein ligase E3B	12	108399821	AI749193	89910	12q24.11	Hs.374067	8	intracellular protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
214955_at	0.224	6.566	2.237	4.068e-02	0.531	-3.865	TMPRSS6	transmembrane protease, serine 6	22	-35791424	AI912086	164656	22q12.3	Hs.370885	16	angiogenesis serine-type endopeptidase activity plasma membrane proteolysis intracellular signaling cascade peptidase activity integral to membrane extracellular matrix organization fibrinolysis
1555763_x_at	-0.240	4.166	-2.237	4.068e-02	0.531	-3.866	MKL1	megakaryoblastic leukemia (translocation) 1	22	-39136237	AF364036	57591	22q13	Hs.654688	37	nucleic acid binding transcription coactivator activity actin monomer binding protein binding nucleus cytoplasm anti-apoptosis positive regulation of transcription
213568_at	-0.302	5.388	-2.237	4.068e-02	0.531	-3.866	OSR2	odd-skipped related 2 (Drosophila)	8	100025806	AI811298	116039	8q22.2	Hs.253247	6	nucleic acid binding intracellular nucleus zinc ion binding positive regulation of cell proliferation metal ion binding embryonic skeletal system morphogenesis
210080_x_at	0.209	4.463	2.237	4.070e-02	0.531	-3.866	CELA3A	chymotrypsin-like elastase family, member 3A	1	22200735	D00306	10136	1p36.12	Hs.654349	7	serine-type endopeptidase activity proteolysis digestion cholesterol metabolic process peptidase activity
212638_s_at	-0.461	10.114	-2.236	4.072e-02	0.531	-3.866	WWP1	WW domain containing E3 ubiquitin protein ligase 1	8	87424109	BF131791	11059	8q21	Hs.655189	30	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding intracellular protein modification process signal transduction central nervous system development negative regulation of transcription protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process interspecies interaction between organisms entry of virus into host cell	Ubiquitin mediated proteolysis Endocytosis
218111_s_at	-0.319	6.252	-2.236	4.072e-02	0.531	-3.866	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase	12	22090425	NM_018686	55907	12p12.1	Hs.311346	13	nucleus N-acylneuraminate cytidylyltransferase activity lipopolysaccharide biosynthetic process transferase activity nucleotidyltransferase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
215412_x_at	0.279	5.382	2.236	4.073e-02	0.531	-3.866	PMS2L2	postmeiotic segregation increased 2-like 2 pseudogene	7	-74815899, 72114615	AB017007	5380	7q11-q22	Hs.292996 Hs.661055 Hs.675888	4	molecular_function ATP binding cellular_component mismatch repair biological_process mismatched DNA binding
223347_at	0.185	6.287	2.236	4.073e-02	0.531	-3.867	MUM1	melanoma associated antigen (mutated) 1	19	1305975, 1307322	AL360266	84939	19p13.3	Hs.515016	6
228157_at	0.319	6.815	2.236	4.074e-02	0.531	-3.867	ZNF207	zinc finger protein 207	17	27701269	AI125646	7756	17q11.2	Hs.500775	7	transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218438_s_at	-0.334	7.314	-2.236	4.074e-02	0.531	-3.867	MED28	mediator complex subunit 28	4	17225370	NM_025205	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
1556421_at	-0.416	3.383	-2.236	4.076e-02	0.532	-3.867	LOC286189	hypothetical protein LOC286189	8		AI890196	286189	8q13.1	Hs.593427	2
201079_at	-0.355	9.237	-2.235	4.080e-02	0.532	-3.868	SYNGR2	synaptogyrin 2	17	73676265	NM_004710	9144	17q25.3	Hs.464210 Hs.708616	5	integral to plasma membrane membrane
210103_s_at	0.285	3.847	2.235	4.081e-02	0.532	-3.868	FOXA2	forkhead box A2	20	-22509641, -22509641	AB028021	3170	20p11	Hs.155651	35	ectoderm formation RNA polymerase II transcription factor activity, enhancer binding nucleus regulation of transcription, DNA-dependent pattern specification process blood coagulation anterior/posterior pattern formation regulation of specific transcription from RNA polymerase II promoter cell differentiation in hindbrain dorsal/ventral neural tube patterning lung development epithelial cell differentiation endocrine pancreas development sequence-specific DNA binding cell part negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter cell development anatomical structure formation involved in morphogenesis neuron fate specification branching morphogenesis of a tube	Maturity onset diabetes of the young
213502_x_at	0.217	6.052	2.235	4.081e-02	0.532	-3.868	LOC91316	glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene	22	-22310675	AA398569	91316	22q11.23	Hs.148656	4
211833_s_at	0.253	3.869	2.235	4.082e-02	0.532	-3.868	BAX	BCL2-associated X protein	19	54149928, 54149928, 54149928	U19599	581	19q13.3-q13.4	Hs.624291	448	B cell apoptosis B cell apoptosis release of cytochrome c from mitochondria cytoplasm mitochondrion mitochondrial outer membrane mitochondrial permeability transition pore complex endoplasmic reticulum endoplasmic reticulum membrane cytosol cytosol DNA fragmentation involved in apoptosis cleavage of lamin transformed cell apoptosis mitochondrial fusion lipid binding induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals negative regulation of survival gene product expression activation of caspase activity by cytochrome c response to toxin establishment or maintenance of transmembrane electrochemical gradient membrane integral to membrane nuclear fragmentation during apoptosis release of matrix enzymes from mitochondria protein homodimerization activity protein homodimerization activity regulation of apoptosis regulation of protein homodimerization activity regulation of protein heterodimerization activity positive regulation of neuron apoptosis mitochondrial fragmentation during apoptosis induction of retinal programmed cell death protein heterodimerization activity protein homooligomerization BH3 domain binding regulation of mitochondrial membrane potential	p53 signaling pathway Apoptosis Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Huntington's disease Prion diseases Pathways in cancer Colorectal cancer
201066_at	0.212	11.243	2.235	4.083e-02	0.532	-3.869	CYC1	cytochrome c-1	8	145221947	NM_001916	1537	8q24.3	Hs.289271	23	mitochondrion mitochondrial inner membrane transport membrane integral to membrane heme binding electron transport chain electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity metal ion binding respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
228513_at	0.219	5.399	2.234	4.087e-02	0.532	-3.869	TMEM219	transmembrane protein 219	16	29880851	AA496243	124446	16p11.2	Hs.460574	1	membrane integral to membrane
216750_at	0.231	4.585	2.234	4.089e-02	0.532	-3.870	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	4	-40506801	AK024871	323	4p14-p13	Hs.479602	12	beta-amyloid binding nucleus cell cycle arrest intracellular signaling cascade transcription factor binding membrane lamellipodium negative regulation of cell growth growth cone synapse regulation of transcription negative regulation of S phase of mitotic cell cycle
215017_s_at	0.207	7.729	2.234	4.091e-02	0.532	-3.870	FNBP1L	formin binding protein 1-like	1	93686426	AW270932	54874	1p22.1	Hs.134060	15	cytoplasm cytoskeleton plasma membrane cell cortex endocytosis lipid binding cytoplasmic vesicle
204778_x_at	0.247	6.252	2.234	4.092e-02	0.532	-3.871	HOXB7	homeobox B7	17	-44039593	AW102783	3217	17q21.3	Hs.436181	39	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation myeloid cell differentiation sequence-specific DNA binding embryonic skeletal system morphogenesis
230630_at	0.221	4.187	2.234	4.093e-02	0.532	-3.871	AK3L1	adenylate kinase 3-like 1	1	65385819, 65386100, 65386473	AI566130	205	1p31.3	Hs.10862 Hs.592601	10	nucleotide binding adenylate kinase activity ATP binding GTP binding mitochondrion mitochondrial matrix nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity	Purine metabolism Metabolic pathways
240349_at	-0.315	5.553	-2.234	4.094e-02	0.532	-3.871	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	AV693202	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
243045_at	0.314	7.291	2.233	4.096e-02	0.532	-3.871	SMYD1	SET and MYND domain containing 1	2	88148496	N75296	150572	2p11.2	Hs.516176	8	DNA binding nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding
1552919_at	0.204	2.365	2.233	4.097e-02	0.532	-3.871	C4orf36	chromosome 4 open reading frame 36	4	-88016381	NM_144645	132989	4q21.3	Hs.339646	4
203311_s_at	-0.299	7.503	-2.233	4.098e-02	0.532	-3.872	ARF6	ADP-ribosylation factor 6	14	49429485	M57763	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
230129_at	-0.326	5.099	-2.233	4.101e-02	0.532	-3.872	PSTK	phosphoseryl-tRNA kinase	10	124729545	BF589448	118672	10q26.13	Hs.281004	4	nucleotide binding magnesium ion binding ATP binding translation kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor	Aminoacyl-tRNA biosynthesis
221829_s_at	0.239	9.161	2.233	4.102e-02	0.532	-3.873	TNPO1	transportin 1	5	72148173, 72179685	AI307759	3842	5q13.2	Hs.482497	58	protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
214077_x_at	0.307	4.459	2.232	4.103e-02	0.532	-3.873	MEIS3P1	Meis homeobox 3 pseudogene 1	17	15630888	H15129	4213	17p12	Hs.356135	4	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
205512_s_at	-0.296	8.186	-2.232	4.107e-02	0.533	-3.874	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	X	-129091019, -129091019, -129091018	NM_004208	9131	Xq25-q26	Hs.424932	58	DNA binding protein binding nucleus cytoplasm mitochondrion mitochondrial intermembrane space DNA fragmentation involved in apoptosis apoptosis DNA damage response, signal transduction resulting in induction of apoptosis electron carrier activity oxidoreductase activity cell redox homeostasis FAD binding oxidation reduction	Apoptosis
203616_at	0.323	9.693	2.231	4.110e-02	0.533	-3.874	POLB	polymerase (DNA directed), beta	8	42315186	NM_002690	5423	8p11.2	Hs.654484	95	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity nucleus nucleoplasm cytoplasm spindle microtubule DNA-dependent DNA replication base-excision repair pyrimidine dimer repair anti-apoptosis response to DNA damage stimulus microtubule binding cell death transferase activity nucleotidyltransferase activity lyase activity enzyme binding sodium ion binding	Base excision repair
204729_s_at	0.240	6.046	2.231	4.111e-02	0.533	-3.875	STX1A	syntaxin 1A (brain)	7	-72751475	NM_004603	6804	7q11.23	Hs.647024	112	SNARE binding positive regulation of neurotransmitter secretion SNAP receptor activity extracellular region plasma membrane plasma membrane neurotransmitter transport intracellular protein transport synaptic transmission response to gravity integral to membrane synaptic vesicle docking during exocytosis vesicle-mediated transport myosin binding calcium ion-dependent exocytosis calcium channel inhibitor activity secretory granule synaptic vesicle membrane protein binding, bridging myosin head/neck binding actomyosin ATP-dependent protein binding positive regulation of exocytosis protein heterodimerization activity calcium-dependent protein binding regulation of insulin secretion	SNARE interactions in vesicular transport
226961_at	0.241	3.995	2.231	4.114e-02	0.533	-3.875	PRR15	proline rich 15	7	29569951	AI347918	222171	7p14.3	Hs.91109	3	multicellular organismal development
1554702_at	0.234	3.856	2.231	4.114e-02	0.533	-3.875	NALCN	sodium leak channel, non-selective	13	-100504130	BC028390	259232	13q32.3	Hs.525146	8	voltage-gated ion channel activity sodium channel activity ion transport sodium ion transport membrane integral to membrane sodium ion binding
206774_at	0.314	5.197	2.231	4.115e-02	0.533	-3.875	FRMPD1	FERM and PDZ domain containing 1	9	37641051	NM_014907	22844	9p13.2	Hs.163990	4	protein binding cytoplasm cytosol cytoskeleton plasma membrane
243581_at	-0.298	2.492	-2.231	4.116e-02	0.533	-3.876	LOC646470	similar to proteaseome (prosome, macropain) 28 subunit, 3	1		AW117229	646470	1q23.3	Hs.659284
236613_at	-0.328	4.330	-2.231	4.117e-02	0.533	-3.876	RBM25	RNA binding motif protein 25	14	72594973	BE466195	58517	14q24.3	Hs.531106	13	nucleotide binding nuclear mRNA splicing, via spliceosome nucleic acid binding mRNA binding cellular_component nucleus cytoplasm nuclear speck
212576_at	0.229	6.907	2.231	4.118e-02	0.533	-3.876	MGRN1	mahogunin, ring finger 1	16	4614826	AB011116	23295	16p13.3	Hs.526494	10	protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
1561504_s_at	-1.777	7.634	-2.230	4.120e-02	0.533	-3.876	MYLK4	myosin light chain kinase family, member 4	6	-2608861	AK096893	340156	6p25.2	Hs.127830	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
223021_x_at	-0.407	7.356	-2.230	4.121e-02	0.533	-3.877	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	BF241590	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
202067_s_at	-0.193	4.818	-2.230	4.122e-02	0.533	-3.877	LDLR	low density lipoprotein receptor	19	11061056	AI861942	3949	19p13.3	Hs.213289 Hs.713967	374	transmembrane receptor activity low-density lipoprotein receptor activity calcium ion binding endosome plasma membrane plasma membrane integral to plasma membrane coated pit protein amino acid O-linked glycosylation lipid metabolic process lipid transport endocytosis steroid metabolic process cholesterol metabolic process endosome membrane very-low-density lipoprotein receptor activity intestinal cholesterol absorption clathrin-coated endocytic vesicle membrane low-density lipoprotein particle low-density lipoprotein particle clearance lipoprotein catabolic process cholesterol homeostasis interspecies interaction between organisms	Endocytosis
223247_at	-0.210	6.851	-2.230	4.123e-02	0.533	-3.877	MED10	mediator complex subunit 10	5	-6425038	BC003353	84246	5p15.31	Hs.13885	12	nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity regulation of transcription
222234_s_at	0.383	5.614	2.229	4.126e-02	0.533	-3.878	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1	16	-88598779, -88598779	AK022644	79007	16q24.3	Hs.301394	5	protein binding cytoplasm
238012_at	0.315	5.615	2.229	4.126e-02	0.533	-3.878	DPP7	dipeptidyl-peptidase 7	9	-139124812	AI620209	29952	9q34.3	Hs.37916	15	aminopeptidase activity protein binding lysosome proteolysis peptidase activity serine-type peptidase activity cytoplasmic vesicle
1554474_a_at	-0.243	2.820	-2.229	4.129e-02	0.533	-3.878	MOXD1	monooxygenase, DBH-like 1	6	-132658886	BC018756	26002	6q23.1-q23.3	Hs.6909	4	monooxygenase activity dopamine beta-monooxygenase activity copper ion binding endoplasmic reticulum histidine catabolic process catecholamine metabolic process cellular process membrane integral to membrane metal ion binding oxidation reduction
226225_at	0.605	6.595	2.229	4.129e-02	0.533	-3.878	MCC	mutated in colorectal cancers	5	-112385694, -112385694	BE967311	4163	5q21	Hs.593171	18	receptor activity protein binding signal transduction
205402_x_at	-0.211	4.382	-2.229	4.129e-02	0.533	-3.878	PRSS2	protease, serine, 2 (trypsin 2)	7	142178777	NM_002770	5645	7q34	Hs.622865	39	serine-type endopeptidase activity calcium ion binding protein binding extracellular region extracellular space proteolysis digestion peptidase activity positive regulation of cell growth collagen catabolic process collagen catabolic process extracellular matrix positive regulation of cell adhesion	Neuroactive ligand-receptor interaction
225800_at	0.207	4.326	2.229	4.130e-02	0.533	-3.879	JAZF1	JAZF zinc finger 1	7	-27836717	AI990891	221895	7p15.2-p15.1	Hs.368944	39	negative regulation of transcription from RNA polymerase II promoter nucleic acid binding transcription corepressor activity intracellular nucleus zinc ion binding transcriptional repressor complex regulation of transcription metal ion binding
200927_s_at	-0.403	7.252	-2.229	4.132e-02	0.533	-3.879	RAB14	RAB14, member RAS oncogene family	9	-122980236	AA919115	51552	9q32-q34.11	Hs.371563 Hs.713585	19	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm
219670_at	0.424	5.782	2.229	4.132e-02	0.533	-3.879	BEND5	BEN domain containing 5	1	-48966126	NM_024603	79656	1p33	Hs.475348	5	Golgi apparatus
219452_at	0.184	4.806	2.229	4.133e-02	0.533	-3.879	DPEP2	dipeptidase 2	16	-66578795	NM_022355	64174	16q22.1	Hs.372633	7	proteolysis peptidase activity metalloexopeptidase activity dipeptidyl-peptidase activity zinc ion binding membrane dipeptidase activity anchored to membrane metal ion binding
212972_x_at	-0.222	6.097	-2.229	4.133e-02	0.533	-3.879	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	4	-40506801	AL080130	323	4p14-p13	Hs.479602	12	beta-amyloid binding nucleus cell cycle arrest intracellular signaling cascade transcription factor binding membrane lamellipodium negative regulation of cell growth growth cone synapse regulation of transcription negative regulation of S phase of mitotic cell cycle
219126_at	-0.388	7.551	-2.228	4.136e-02	0.533	-3.880	PHF10	PHD finger protein 10	6	-169845925	NM_018288	55274	6q27	Hs.435933	14	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
240161_s_at	-0.275	3.157	-2.228	4.137e-02	0.533	-3.880	CDC20B	cell division cycle 20 homolog B (S. cerevisiae)	5	-54444579	AI470220	166979	5q11.2	Hs.669184	3
207812_s_at	-0.312	7.617	-2.228	4.139e-02	0.533	-3.880	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	NM_015530	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
233006_at	0.265	5.536	2.228	4.139e-02	0.533	-3.880	SEPT4	septin 4	17	-53952614, -53952614	AU147957	5414	17q22-q23	Hs.287518	29	nucleotide binding cytokinesis GTPase activity structural molecule activity protein binding GTP binding nucleus cytoplasm cell cycle
220610_s_at	-0.345	6.899	-2.228	4.141e-02	0.533	-3.881	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	NM_006309	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
203510_at	-0.504	7.360	-2.228	4.141e-02	0.533	-3.881	MET	met proto-oncogene (hepatocyte growth factor receptor)	7	116099694	BG170541	4233	7q31	Hs.132966	256	nucleotide binding activation of MAPK activity neuron migration receptor activity hepatocyte growth factor receptor activity protein binding ATP binding membrane fraction integral to plasma membrane cell surface receptor linked signal transduction multicellular organismal development brain development muscle organ development lactation basal plasma membrane membrane transferase activity flagellum sperm motility adult behavior protein amino acid autophosphorylation hepatocyte growth factor receptor signaling pathway myoblast proliferation	Cytokine-cytokine receptor interaction Endocytosis Axon guidance Focal adhesion Adherens junction Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Melanoma
209698_at	0.251	6.656	2.227	4.143e-02	0.533	-3.881	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AF216493	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
203846_at	-0.305	7.396	-2.227	4.144e-02	0.533	-3.881	TRIM32	tripartite motif-containing 32	9	118489401	BC003154	22954	9q33.1	Hs.591910	18	transcription coactivator activity intracellular nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process ubiquitin binding protein self-association fat cell differentiation metal ion binding	Ubiquitin mediated proteolysis
229517_at	0.300	5.782	2.227	4.146e-02	0.533	-3.882	PTPDC1	protein tyrosine phosphatase domain containing 1	9	95832896, 95886566	BE046919	138639	9q22.32	Hs.437943	2	protein tyrosine phosphatase activity protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
221768_at	0.276	7.636	2.227	4.149e-02	0.533	-3.882	SFPQ	splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)	1	-35421789	AV705803	6421	1p34.3	Hs.355934	47	nucleotide binding DNA binding RNA binding protein binding nucleus DNA repair DNA recombination mRNA processing response to DNA damage stimulus RNA splicing nuclear matrix regulation of transcription
232298_at	-0.610	7.873	-2.226	4.150e-02	0.533	-3.883	hCG_1806964	hypothetical LOC401093	3	-153463102	AK026494	401093	3q25.1	Hs.201858 Hs.558914 Hs.719379	3
208036_at	0.261	4.091	2.226	4.154e-02	0.534	-3.883	OPN1SW	opsin 1 (cone pigments), short-wave-sensitive	7	-128199778	NM_001708	611	7q32.1	Hs.656404	14	photoreceptor outer segment G-protein coupled receptor activity integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway visual perception phototransduction photoreceptor activity membrane protein-chromophore linkage response to stimulus
227320_at	0.311	6.014	2.226	4.155e-02	0.534	-3.884	FAM101A	family with sequence similarity 101, member A	12	123339662	AW264333	144347	12q24.31	Hs.432901	3
206398_s_at	0.220	4.807	2.226	4.157e-02	0.534	-3.884	CD19	CD19 molecule	16	28850760	NM_001770	930	16p11.2	Hs.652262	49	receptor signaling protein activity protein binding plasma membrane integral to plasma membrane cellular defense response cell surface receptor linked signal transduction external side of plasma membrane B cell receptor signaling pathway	Hematopoietic cell lineage B cell receptor signaling pathway Primary immunodeficiency
203710_at	0.494	4.914	2.225	4.159e-02	0.534	-3.885	ITPR1	inositol 1,4,5-triphosphate receptor, type 1	3	4510033	NM_002222	3708	3p26-p25	Hs.567295 Hs.715765	87	response to hypoxia ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium channel activity calcium ion binding protein binding endoplasmic reticulum ion transport calcium ion transport signal transduction cell death calcium ion transmembrane transporter activity membrane integral to membrane platelet dense granule membrane platelet dense tubular network membrane	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease Huntington's disease
228075_x_at	0.251	6.925	2.225	4.161e-02	0.534	-3.885	TFB1M	transcription factor B1, mitochondrial	6	-155620481	AI341648	51106	6q25.1-q25.3	Hs.279908	15	rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity DNA binding mitochondrion methyltransferase activity rRNA methyltransferase activity transferase activity mitochondrial nucleoid regulation of transcription
222269_at	0.386	4.901	2.225	4.165e-02	0.534	-3.886	APOOL	apolipoprotein O-like	X	84145560	W87634	139322	Xq21.1	Hs.512181 Hs.706885	7	extracellular region mitochondrion mitochondrial inner membrane
221280_s_at	-0.304	5.421	-2.225	4.165e-02	0.534	-3.886	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	NM_019619	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
211676_s_at	-0.657	6.362	-2.225	4.166e-02	0.534	-3.886	IFNGR1	interferon gamma receptor 1	6	-137560313	AF056979	3459	6q23.3	Hs.520414	104	receptor activity interferon-gamma receptor activity integral to plasma membrane signal transduction response to virus membrane cytokine binding	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity
223002_s_at	-0.189	6.117	-2.224	4.167e-02	0.534	-3.886	XRN2	5'-3' exoribonuclease 2	20	21231941	AL136841	22803	20p11.2-p11.1	Hs.255932	18	DNA catabolic process, exonucleolytic nucleic acid binding 5'-3' exoribonuclease activity protein binding intracellular nucleus nucleolus transcription termination mRNA processing RNA catabolic process spermatogenesis zinc ion binding cell growth hydrolase activity regulation of transcription metal ion binding	RNA degradation
232407_at	-0.172	5.600	-2.224	4.169e-02	0.534	-3.887	MUC17	mucin 17, cell surface associated	7	100450083	AK026404	140453	7q22.1	Hs.271819	9	extracellular region plasma membrane biological_process integral to membrane extracellular matrix constituent, lubricant activity
211081_s_at	-0.289	3.392	-2.223	4.175e-02	0.534	-3.888	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	14	-49954992	Z25426	11183	14q11.2-q21	Hs.130491	14	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding cytoplasm protein amino acid phosphorylation response to stress protein kinase cascade activation of JUN kinase activity transferase activity
1554026_a_at	0.210	4.354	2.223	4.177e-02	0.534	-3.888	MYO10	myosin X	5	-16715015	BC041694	4651	5p15.1-p14.3	Hs.481720	19	nucleotide binding motor activity actin binding ATP binding cytoskeleton signal transduction myosin complex	Fc gamma R-mediated phagocytosis
225915_at	-0.664	5.996	-2.223	4.179e-02	0.534	-3.889	CAB39L	calcium binding protein 39-like	13	-48780786, -48780786	AL138875	81617	13q14.2	Hs.87159	9	protein binding	mTOR signaling pathway
230030_at	-1.119	4.863	-2.223	4.180e-02	0.534	-3.889	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	X	-131587718	AI767756	90161	Xq26.2	Hs.385956	7	sulfotransferase activity membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
200739_s_at	-0.176	7.331	-2.222	4.183e-02	0.534	-3.890	SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	21	-45049959	BG338532	6612	21q22.3	Hs.474005	40	kinetochore protein binding cytoplasm protein sumoylation modification-dependent protein catabolic process
212779_at	-0.718	9.309	-2.222	4.184e-02	0.534	-3.890	KIAA1109	KIAA1109	4	123311207	AB029032	84162	4q27	Hs.408142	12	membrane integral to membrane
240106_at	-0.247	6.007	-2.222	4.185e-02	0.534	-3.890	GNPTAB	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	12	-100663407	AI633523	79158	12q23.2	Hs.46850	16	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity calcium ion binding nucleus Golgi apparatus transcription factor binding membrane integral to membrane transferase activity cell differentiation	Lysosome
1559566_at	-0.278	3.537	-2.222	4.185e-02	0.534	-3.890	FBXO42	F-box protein 42	1	-16449145	AL833207	54455	1p36.23-p36.11	Hs.522384	7	modification-dependent protein catabolic process
229001_at	-0.513	6.812	-2.222	4.188e-02	0.534	-3.890	PPP1R3E	protein phosphatase 1, regulatory (inhibitor) subunit 3E	14	-22834952	BE259127	90673	14q11.2	Hs.601513 Hs.672733	3	carbohydrate metabolic process glycogen metabolic process
217976_s_at	-0.297	7.682	-2.222	4.188e-02	0.534	-3.890	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	3	-32542470	NM_016141	51143	3p22.3	Hs.529495	11	nucleotide binding motor activity ATP binding microtubule dynein complex
202605_at	0.283	6.700	2.222	4.188e-02	0.534	-3.890	GUSB	glucuronidase, beta	7	-65063107	NM_000181	2990	7q21.11	Hs.255230	45	beta-glucuronidase activity lysosome carbohydrate metabolic process glycosaminoglycan catabolic process metabolic process cation binding	Pentose and glucuronate interconversions Starch and sucrose metabolism Glycosaminoglycan degradation Porphyrin and chlorophyll metabolism Drug metabolism - other enzymes Metabolic pathways Lysosome
1561451_a_at	0.229	3.793	2.222	4.188e-02	0.534	-3.891	ADAM29	ADAM metallopeptidase domain 29	4	176076083	BC034301	11086	4q34	Hs.126838	5	metalloendopeptidase activity integral to plasma membrane proteolysis spermatogenesis zinc ion binding membrane
222989_s_at	-0.296	7.341	-2.222	4.189e-02	0.534	-3.891	UBQLN1	ubiquilin 1	9	-85464697	NM_013438	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
215014_at	0.433	2.701	2.221	4.190e-02	0.534	-3.891	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	1	-112119976	AL512727	3752	1p13.3	Hs.666367	23	voltage-gated ion channel activity voltage-gated potassium channel activity A-type (transient outward) potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex zinc ion binding potassium ion binding sarcolemma neuron projection cell soma metal ion binding
201071_x_at	-0.230	9.823	-2.221	4.191e-02	0.534	-3.891	SF3B1	splicing factor 3b, subunit 1, 155kDa	2	-197991765, -197964942	NM_012433	23451	2q33.1	Hs.632554	34	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome protein binding nucleus spliceosomal complex RNA splicing nuclear speck RNA splicing factor activity, transesterification mechanism
213331_s_at	0.276	5.645	2.221	4.191e-02	0.534	-3.891	NEK1	NIMA (never in mitosis gene a)-related kinase 1	4	-170551003	AV700007	4750	4q33	Hs.481181	11	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division
213599_at	-0.496	6.367	-2.221	4.194e-02	0.534	-3.892	OIP5	Opa interacting protein 5	15	-39388757	BE045993	11339	15q15.1	Hs.661645	6	chromosome, centromeric region chromatin protein binding cellular_component nucleus cell cycle mitosis cell communication chromocenter Cajal body cell division
221527_s_at	-0.435	7.473	-2.220	4.199e-02	0.534	-3.893	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AF196185	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
215472_at	0.255	4.130	2.220	4.201e-02	0.534	-3.893	PACRG	PARK2 co-regulated	6	163068153, 163068991	AI017119	135138	6q26	Hs.25791	20
235121_at	0.315	4.590	2.220	4.201e-02	0.534	-3.893	ZNF542	zinc finger protein 542	19	61571279, 61571476	BE966943	147947	19q13.43	Hs.467326	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
232067_at	0.273	3.182	2.220	4.203e-02	0.534	-3.893	C6orf168	chromosome 6 open reading frame 168	6	-99827513	BC004869	84553	6q16.2	Hs.573245	5	mitochondrial outer membrane protein targeting to mitochondrion
203582_s_at	-0.246	7.410	-2.220	4.204e-02	0.534	-3.894	RAB4A	RAB4A, member RAS oncogene family	1	227473501	NM_004578	5867	1q42-q43	Hs.296169	43	nucleotide binding GTPase activity GTP binding cytoplasm small GTPase mediated signal transduction protein transport membrane	Endocytosis
201455_s_at	-0.340	8.739	-2.220	4.206e-02	0.534	-3.894	NPEPPS	aminopeptidase puromycin sensitive	17	42963442	AJ132583	9520	17q21	Hs.443837	14	aminopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
211865_s_at	-0.246	4.398	-2.219	4.206e-02	0.534	-3.894	FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	19	3457294, 3473953	AB013463	51343	19p13.3	Hs.413133	35	protein binding nucleus nucleoplasm anaphase-promoting complex cytoplasm cytosol ubiquitin-dependent protein catabolic process cell cycle mitosis enzyme activator activity cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
1556204_a_at	0.339	4.241	2.219	4.208e-02	0.534	-3.895	ZNF814	zinc finger protein 814	19	-63072558	AK096401	730051	19q13.43	Hs.634143 Hs.669024 Hs.719319	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
232355_at	-0.209	2.713	-2.219	4.209e-02	0.534	-3.895	SNORD114-3	small nucleolar RNA, C/D box 114-3	14	100489438	AU146318	767579	14q32	Hs.613596	2
217608_at	-0.365	5.091	-2.219	4.210e-02	0.534	-3.895	SFRS12IP1	SFRS12-interacting protein 1	5	-64049733	AW408767	285672	5q12.3	Hs.69504	3	nucleic acid binding mRNA processing zinc ion binding RNA splicing metal ion binding
206376_at	0.161	2.644	2.219	4.210e-02	0.534	-3.895	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15	12	-83798761, -83777399	NM_018057	55117	12q21.3	Hs.44424	10	neurotransmitter:sodium symporter activity integral to plasma membrane neurotransmitter transport symporter activity membrane
226484_at	-0.253	8.379	-2.219	4.211e-02	0.534	-3.895	ZBTB47	zinc finger and BTB domain containing 47	3	42675877	AA532640	92999	3p22.1	Hs.409561	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1553750_a_at	-0.223	2.716	-2.219	4.211e-02	0.534	-3.895	FAM76B	family with sequence similarity 76, member B	11	-95141753	NM_144664	143684	11q21	Hs.288304	11
222407_s_at	-0.403	10.913	-2.219	4.212e-02	0.534	-3.895	ZFP106	zinc finger protein 106 homolog (mouse)	15	-40492312	AI493587	64397	15q15.1	Hs.511143	9	opioid peptide activity intracellular membrane fraction nucleus nucleolus cytosol zinc ion binding insulin receptor signaling pathway SH3 domain binding metal ion binding
210720_s_at	0.275	7.677	2.219	4.212e-02	0.534	-3.895	NECAB3	N-terminal EF-hand calcium binding protein 3	20	-31708553	AB039947	63941	20q11.22	Hs.516986	11	Golgi cis cisterna Golgi cis cisterna calcium ion binding protein binding protein binding protein binding nucleus cytoplasm cytoplasm endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus protein secretion oxidoreductase activity antibiotic biosynthetic process protein metabolic process protein metabolic process regulation of amyloid precursor protein biosynthetic process
1562988_at	-0.181	3.259	-2.218	4.215e-02	0.534	-3.896	ZNF397OS	zinc finger protein 397 opposite strand	18	-31086816	AF373035	100101467	18q12.2	Hs.464896	3	transcription factor activity intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
241392_at	0.237	4.611	2.218	4.221e-02	0.534	-3.897	TMEM39A	transmembrane protein 39A	3	-120632390	BE551352	55254	3q13.33	Hs.656003	3	membrane integral to membrane
207509_s_at	0.210	3.543	2.217	4.223e-02	0.534	-3.898	LAIR2	leukocyte-associated immunoglobulin-like receptor 2	19	59705824	NM_002288	3904	19q13.4	Hs.43803	9	receptor activity extracellular region
205386_s_at	0.172	2.109	2.217	4.227e-02	0.534	-3.898	MDM2	Mdm2 p53 binding protein homolog (mouse)	12	67488237, 67489063	NM_002392	4193	12q14.3-q15	Hs.484551	555	negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding	Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia
218967_s_at	0.495	6.965	2.217	4.227e-02	0.534	-3.898	PTER	phosphotriesterase related	10	16518972	NM_030664	9317	10p12	Hs.444321 Hs.716660	6	zinc ion binding catabolic process hydrolase activity, acting on ester bonds metal ion binding
222338_x_at	0.196	6.879	2.217	4.228e-02	0.535	-3.899	LOC646808	similar to L antigen family, member 3	9		AI375965	646808	9p21.1
225639_at	0.561	6.745	2.217	4.229e-02	0.535	-3.899	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	N21390	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
202046_s_at	0.158	2.928	2.216	4.231e-02	0.535	-3.899	GRLF1	glucocorticoid receptor DNA binding factor 1	19	52113772	NM_004491	2909	19q13.3	Hs.509447	26	DNA binding transcription corepressor activity GTPase activator activity intracellular nucleus cytoplasm signal transduction negative regulation of transcription	Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
215505_s_at	-0.440	5.422	-2.216	4.232e-02	0.535	-3.899	STRN3	striatin, calmodulin binding protein 3	14	-30432755	AF243424	29966	14q13-q21	Hs.21016 Hs.401843	13	calmodulin binding membrane fraction nucleus cytoplasm cytosol cell cycle membrane
218387_s_at	0.261	6.166	2.216	4.236e-02	0.535	-3.900	PGLS	6-phosphogluconolactonase	19	17483431	NM_012088	25796	19p13.2	Hs.466165	5	carbohydrate metabolic process pentose-phosphate shunt hydrolase activity 6-phosphogluconolactonase activity	Pentose phosphate pathway Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
201917_s_at	0.309	9.167	2.215	4.245e-02	0.536	-3.902	SLC25A36	solute carrier family 25, member 36	3	142143351	AI694452	55186	3q23	Hs.144130	7	transporter activity binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane response to estradiol stimulus
223411_at	0.205	8.047	2.215	4.246e-02	0.536	-3.902	MIF4GD	MIF4G domain containing	17	-70773905	AF225422	57409	17q25.1	Hs.325631	5	protein binding nucleus cytoplasm regulation of translation RNA metabolic process
216979_at	-2.421	5.170	-2.214	4.247e-02	0.536	-3.902	NR4A3	nuclear receptor subfamily 4, group A, member 3	9	101623957, 101623957, 101628829	X89894	8013	9q22	Hs.279522	24	mesoderm formation transcription factor activity steroid hormone receptor activity thyroid hormone receptor activity binding nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding transcription activator activity adult behavior sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter metal ion binding semicircular canal morphogenesis neuromuscular process controlling balance vestibular reflex
206342_x_at	-0.303	6.047	-2.214	4.247e-02	0.536	-3.903	IDS	iduronate 2-sulfatase	X	-148376566, -148368202	NM_006123	3423	Xq28	Hs.460960	73	iduronate-2-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
203267_s_at	-0.217	6.407	-2.214	4.248e-02	0.536	-3.903	DRG2	developmentally regulated GTP binding protein 2	17	17932007	BF223206	1819	17p11.2	Hs.78582	12	nucleotide binding GTP binding intracellular cytoplasm signal transduction
205020_s_at	0.285	5.164	2.214	4.249e-02	0.536	-3.903	ARL4A	ADP-ribosylation factor-like 4A	7	12693005, 12693485	NM_005738	10124	7p21-p15.3	Hs.245540	8	nucleotide binding GTPase activity protein binding GTP binding intracellular nucleus nucleolus small GTPase mediated signal transduction
1553893_at	0.235	5.005	2.214	4.253e-02	0.536	-3.904	CCDC105	coiled-coil domain containing 105	19	14982538	NM_173482	126402	19p13.12	Hs.375985	2
210716_s_at	-0.462	7.410	-2.214	4.253e-02	0.536	-3.904	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	M97501	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
220646_s_at	0.411	3.337	2.213	4.257e-02	0.536	-3.905	KLRF1	killer cell lectin-like receptor subfamily F, member 1	12	9871343	NM_016523	51348	12p13.2-p12.3	Hs.183125	6	binding sugar binding integral to plasma membrane cell surface receptor linked signal transduction membrane MHC class I receptor activity
215680_at	0.208	4.756	2.213	4.257e-02	0.536	-3.905	KIAA1654	KIAA1654 protein	22		AB051441	85368		Hs.658191	1
239742_at	0.571	5.071	2.213	4.258e-02	0.536	-3.905	TULP4	tubby like protein 4	6	158653679	H15278	56995	6q25-q26	Hs.486993	7	transcription factor activity protein binding cellular_component cytoplasm regulation of transcription, DNA-dependent intracellular signaling cascade response to nutrient modification-dependent protein catabolic process
214953_s_at	0.329	6.705	2.213	4.259e-02	0.536	-3.905	APP	amyloid beta (A4) precursor protein	21	-26174732	X06989	351	21q21.2 21q21.3	Hs.434980	835	serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity iron ion binding copper ion binding extracellular region extracellular region cytoplasm Golgi apparatus plasma membrane integral to plasma membrane coated pit cellular copper ion homeostasis endocytosis cell adhesion Notch signaling pathway heparin binding cell death zinc ion binding cell surface peptidase inhibitor activity platelet alpha granule lumen acetylcholine receptor binding identical protein binding metal ion binding neuromuscular process neuron apoptosis	Alzheimer's disease
231056_at	0.221	5.900	2.213	4.263e-02	0.537	-3.906	LOC339352	similar to Putative ATP-binding domain-containing protein 3-like protein	19		AI479923	339352	19q13.41
209443_at	0.894	7.072	2.212	4.268e-02	0.537	-3.907	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	14	94117483	J02639	5104	14q32.1	Hs.159628	62	protease binding serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular region spermatogenesis fusion of sperm to egg plasma membrane heparin binding membrane peptidase inhibitor activity acrosin binding protein complex negative regulation of proteolysis	Complement and coagulation cascades
203430_at	0.225	10.424	2.211	4.275e-02	0.537	-3.908	HEBP2	heme binding protein 2	6	138767028	NM_014320	23593	6q24	Hs.486589	8	cytoplasm
214145_s_at	-0.352	7.427	-2.211	4.275e-02	0.537	-3.908	SPTB	spectrin, beta, erythrocytic	14	-64302901, -64282753	BG223341	6710	14q23-q24.2	Hs.417303	62	structural constituent of cytoskeleton protein binding cytoplasm cell cortex spectrin spectrin-associated cytoskeleton actin cytoskeleton intrinsic to internal side of plasma membrane protein complex actin filament binding actin filament capping
209061_at	-0.362	7.687	-2.211	4.275e-02	0.537	-3.908	NCOA3	nuclear receptor coactivator 3	20	45564063	AI761748	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
202745_at	-0.207	7.270	-2.211	4.277e-02	0.537	-3.909	USP8	ubiquitin specific peptidase 8	15	48503870	NM_005154	9101	15q21.2	Hs.644563	25	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding ubiquitin-dependent protein catabolic process peptidase activity cell proliferation SH3 domain binding	Endocytosis
204980_at	0.307	6.636	2.211	4.279e-02	0.537	-3.909	CLOCK	clock homolog (mouse)	4	-55993416	NM_004898	9575	4q12	Hs.436975	72	transcription factor activity histone acetyltransferase activity signal transducer activity protein binding nucleus transcription factor complex nucleolus cytoplasm signal transduction circadian rhythm acyltransferase activity photoperiodism transferase activity positive regulation of transcription from RNA polymerase II promoter	Circadian rhythm - mammal
1561961_at	-0.190	3.118	-2.210	4.280e-02	0.537	-3.909	DKFZp686A1627	PHD finger protein 2 pseudogene-like	13	-18518292	AL832753	266695	13q11	Hs.614937
219574_at	0.220	3.461	2.210	4.282e-02	0.537	-3.910	MARCH1	membrane-associated ring finger (C3HC4) 1	4	-164668498	NM_017923	55016	4q32.2-q32.3	Hs.608487 Hs.696248	5	zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process cytoplasmic vesicle metal ion binding
225347_at	-0.208	6.601	-2.210	4.282e-02	0.537	-3.910	ARL8A	ADP-ribosylation factor-like 8A	1	-200368599	AL520984	127829	1q32.1	Hs.497399 Hs.604697	7	nucleotide binding GTPase activity GTP binding intracellular cytoplasm lysosomal membrane endosome chromosome segregation small GTPase mediated signal transduction membrane midbody late endosome membrane alpha-tubulin binding beta-tubulin binding spindle midzone
227450_at	0.265	3.794	2.210	4.286e-02	0.537	-3.910	ERP27	endoplasmic reticulum protein 27	12	-14958243	AI051248	121506	12p12.3	Hs.162143	6	endoplasmic reticulum endoplasmic reticulum lumen
224514_x_at	0.278	5.304	2.210	4.287e-02	0.537	-3.910	IL17RC	interleukin 17 receptor C	3	9933763	BC006411	84818	3p25.3 3p25.3-p24.1	Hs.129959	14	receptor activity plasma membrane integral to membrane
202776_at	-0.267	7.875	-2.209	4.288e-02	0.537	-3.911	DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	1	-94107923	NM_014597	30836	1p22.1	Hs.85769	10	nucleus regulation of transcription
1552491_at	0.465	9.274	2.209	4.288e-02	0.537	-3.911	IDI2	isopentenyl-diphosphate delta isomerase 2	10	-1054846	NM_033261	91734	10p15.3	Hs.591325 Hs.9270	6	magnesium ion binding isopentenyl-diphosphate delta-isomerase activity peroxisome cytosol cholesterol biosynthetic process isoprenoid biosynthetic process carotenoid biosynthetic process hydrolase activity isomerase activity	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
213748_at	0.221	5.183	2.209	4.290e-02	0.537	-3.911	TRIM66	tripartite motif-containing 66	11	-8590161	AW271713	9866	11p15.4	Hs.130836	4	protein binding intracellular nucleus zinc ion binding chromocenter transcription repressor activity protein homodimerization activity negative regulation of transcription, DNA-dependent metal ion binding
238600_at	-0.159	4.314	-2.209	4.292e-02	0.537	-3.912	JAKMIP1	janus kinase and microtubule interacting protein 1	4	-6106382, -6078826	AW157571	152789	4p16.1	Hs.479066	10	peripheral to membrane of membrane fraction RNA binding cytoplasm cytoskeleton microtubule protein transport membrane ribonucleoprotein complex GABA receptor binding
226660_at	-0.345	8.434	-2.209	4.296e-02	0.537	-3.912	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	AI142096	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
206265_s_at	0.195	3.154	2.208	4.297e-02	0.537	-3.912	GPLD1	glycosylphosphatidylinositol specific phospholipase D1	6	-24581304, -24536383	NM_001503	2822	6p22.3-p22.2	Hs.533291	26	glycosylphosphatidylinositol phospholipase D activity extracellular region hydrolase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
201795_at	-0.248	7.021	-2.208	4.298e-02	0.537	-3.913	LBR	lamin B receptor	1	-223655826, -223655826	NM_002296	3930	1q42.1	Hs.435166	33	DNA binding receptor activity lamin binding nucleus nuclear envelope integral to nuclear inner membrane membrane integral to membrane delta14-sterol reductase activity
1557729_at	0.203	5.142	2.208	4.298e-02	0.537	-3.913	LOC100131848	FP2025	10		AK097099	100131848	10q26.11	Hs.711375	1
201296_s_at	0.379	9.058	2.208	4.301e-02	0.537	-3.913	WSB1	WD repeat and SOCS box-containing 1	17	22645232	NM_015626	26118	17q11.1	Hs.446017	21	molecular_function protein binding cellular_component intracellular intracellular signaling cascade biological_process modification-dependent protein catabolic process
223254_s_at	-0.256	4.410	-2.208	4.301e-02	0.537	-3.913	G2E3	G2/M-phase specific E3 ubiquitin ligase	14	30098079	AA887053	55632	14q12	Hs.509008 Hs.605081	13	protein polyubiquitination blastocyst development ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm Golgi apparatus protein modification process multicellular organismal development zinc ion binding ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process negative regulation of apoptosis metal ion binding
206955_at	0.361	6.920	2.208	4.302e-02	0.538	-3.914	AQP7	aquaporin 7	9	-33374947	NM_001170	364	9p13	Hs.455323	15	transporter activity integral to plasma membrane generation of precursor metabolites and energy transport water transport excretion water channel activity glycerol channel activity glycerol transport membrane	PPAR signaling pathway
214431_at	-0.256	7.161	-2.207	4.305e-02	0.538	-3.914	GMPS	guanine monphosphate synthetase	3	157071018	NM_003875	8833	3q24	Hs.591314	11	nucleotide binding GMP synthase activity GMP synthase (glutamine-hydrolyzing) activity ATP binding cytoplasm purine nucleotide biosynthetic process GMP biosynthetic process glutamine metabolic process biosynthetic process purine base biosynthetic process ligase activity	Purine metabolism Drug metabolism - other enzymes Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
212785_s_at	-0.259	7.489	-2.207	4.305e-02	0.538	-3.914	LARP7	La ribonucleoprotein domain family, member 7	4	113777568, 113778060	AA160181	51574	4q25	Hs.713663	11	nucleotide binding RNA binding nucleus nucleoplasm cytoplasm Golgi apparatus RNA processing ribonucleoprotein complex
209456_s_at	-0.235	4.566	-2.207	4.306e-02	0.538	-3.914	FBXW11	F-box and WD repeat domain containing 11	5	-171221160	AB033281	23291	5q35.1	Hs.484138	14	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding cytoplasm Wnt receptor signaling pathway protein ubiquitination modification-dependent protein catabolic process	Ubiquitin mediated proteolysis Wnt signaling pathway Hedgehog signaling pathway
227013_at	-0.362	8.565	-2.207	4.306e-02	0.538	-3.914	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	13	-20445175	AI535735	26524	13q11-q12	Hs.78960	17	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding spindle pole protein serine/threonine kinase activity ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation cell cycle mitosis protein kinase cascade hormone-mediated signaling transferase activity negative regulation of cyclin-dependent protein kinase activity cell division
1555467_a_at	-0.176	5.234	-2.207	4.310e-02	0.538	-3.915	CUGBP1	CUG triplet repeat, RNA binding protein 1	11	-47446520, -47446520, -47446520	AF267533	10658	11p11	Hs.632137	34	nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding
221050_s_at	0.363	7.075	2.206	4.313e-02	0.538	-3.916	GTPBP2	GTP binding protein 2	6	-43696195	NM_019096	54676	6p21-p12	Hs.485449	7	nucleotide binding GTPase activity GTP binding
241433_at	0.278	4.745	2.206	4.314e-02	0.538	-3.916	RCOR3	REST corepressor 3	1	209499330, 209499330, 209499911	AI023806	55758	1q32.2	Hs.356399	10	DNA binding protein binding nucleus nucleolus cytoplasm regulation of transcription
202595_s_at	0.244	6.046	2.206	4.317e-02	0.538	-3.916	LEPROTL1	leptin receptor overlapping transcript-like 1	8	30072463, 30072463	AF161461	23484	8p21.2-p21.1	Hs.146585	8	membrane integral to membrane
1554806_a_at	-0.280	6.320	-2.206	4.318e-02	0.538	-3.917	FBXO8	F-box protein 8	4	-175394384	BC040456	26269	4q34.1	Hs.76917	9	ubiquitin ligase complex ARF guanyl-nucleotide exchange factor activity intracellular ubiquitin-dependent protein catabolic process regulation of ARF protein signal transduction
233990_at	-0.159	3.948	-2.206	4.318e-02	0.538	-3.917	C19orf61	chromosome 19 open reading frame 61	19	-48927140	AK022948	56006	19q13.31	Hs.466875	7	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein binding intracellular
210027_s_at	0.207	9.080	2.206	4.319e-02	0.538	-3.917	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	14	19993129	M80261	328	14q11.2-q12	Hs.73722	235	magnesium ion binding DNA binding transcription coactivator activity transcription corepressor activity DNA-(apurinic or apyrimidinic site) lyase activity endodeoxyribonuclease activity ribonuclease H activity phosphodiesterase I activity uracil DNA N-glycosylase activity protein binding intracellular nucleus nucleoplasm cytoplasm endoplasmic reticulum centrosome ribosome base-excision repair transcription from RNA polymerase II promoter response to DNA damage stimulus 3'-5' exonuclease activity oxidoreductase activity lyase activity cell redox homeostasis perinuclear region of cytoplasm regulation of DNA binding	Base excision repair
219434_at	0.214	3.237	2.206	4.319e-02	0.538	-3.917	TREM1	triggering receptor expressed on myeloid cells 1	6	-41351689	NM_018643	54210	6p21.1	Hs.283022	42	receptor activity extracellular region plasma membrane plasma membrane humoral immune response intracellular signaling cascade integral to membrane
204511_at	-0.184	5.305	-2.205	4.324e-02	0.538	-3.918	FARP2	FERM, RhoGEF and pleckstrin domain protein 2	2	241944383	NM_014808	9855	2q37.3	Hs.657318 Hs.679161	9	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity binding intracellular cytoplasm cytoskeleton cytoskeletal protein binding neuron remodeling Rac protein signal transduction extrinsic to membrane regulation of Rho protein signal transduction	Adherens junction
232588_at	0.238	4.360	2.205	4.327e-02	0.538	-3.919	STAG1	stromal antigen 1	3	-137538688	AI038943	10274	3q22.3	Hs.412586	11	chromatin protein binding nucleus cell cycle chromosome segregation mitosis cell division	Cell cycle
1555733_s_at	0.157	2.512	2.205	4.327e-02	0.538	-3.919	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	2	-224328290	AF393369	130340	2q36.1	Hs.632555	13	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane membrane coat clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
223212_at	-0.248	7.546	-2.205	4.328e-02	0.538	-3.919	ZDHHC16	zinc finger, DHHC-type containing 16	10	99195919, 99195936	BC004535	84287	10q24.1	Hs.76662	6	endoplasmic reticulum apoptosis zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
236288_at	-0.290	5.582	-2.204	4.331e-02	0.538	-3.919	RNF34	ring finger protein 34	12	120322284	AW572402	80196	12q24.31	Hs.292804	11	protein binding nucleus apoptosis zinc ion binding membrane nuclear speck ligase activity modification-dependent protein catabolic process metal ion binding
234734_s_at	0.196	7.362	2.204	4.331e-02	0.538	-3.919	TNRC6A	trinucleotide repeat containing 6A	16	24648549	AK025696	27327	16p11.2	Hs.655057	28	nucleotide binding cytoplasmic mRNA processing body RNA binding cytoplasm regulation of translation gene silencing by RNA micro-ribonucleoprotein complex gene silencing by miRNA, negative regulation of translation
229618_at	-0.259	5.703	-2.204	4.331e-02	0.538	-3.919	SNX16	sorting nexin 16	8	-82874372	AW150236	64089	8q21.13	Hs.492121	7	protein binding cell communication protein transport phosphoinositide binding
211559_s_at	-0.334	3.531	-2.204	4.331e-02	0.538	-3.919	CCNG2	cyclin G2	4	78297380	L49506	901	4q21.1	Hs.13291	12	cell cycle checkpoint cytoplasm cell cycle mitosis cell division	p53 signaling pathway
230235_at	0.215	6.164	2.204	4.332e-02	0.538	-3.919	MCTS1	malignant T cell amplified sequence 1	X	119621771, 119622579	BE348430	28985	Xq22-q24	Hs.102696 Hs.670803	12	RNA binding cytoplasm response to DNA damage stimulus cell cycle positive regulation of cell proliferation regulation of growth regulation of transcription
232013_at	-0.219	3.153	-2.204	4.333e-02	0.538	-3.920	C9orf102	chromosome 9 open reading frame 102	9	97677720	AL133663	375748	9q22.32	Hs.432364	4	nucleotide binding DNA binding helicase activity ATP binding nucleus DNA repair response to DNA damage stimulus ATP-dependent helicase activity hydrolase activity
1558214_s_at	-0.176	5.290	-2.203	4.338e-02	0.538	-3.921	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	5	138117005	BG330076	1495	5q31	Hs.534797 Hs.656653	70	structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding	Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC)
222151_s_at	-0.287	6.749	-2.203	4.339e-02	0.538	-3.921	CEP63	centrosomal protein 63kDa	3	135687264, 135687264, 135687586, 135687736	AK023738	80254	3q22.2	Hs.443301	11	DNA damage checkpoint spindle pole protein binding centrosome spindle assembly
217593_at	0.242	6.065	2.203	4.341e-02	0.538	-3.921	ZSCAN18	zinc finger and SCAN domain containing 18	19	-63310783, -63287021, -63287021	AI375002	65982	19q13.43	Hs.235390	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207871_s_at	-0.487	5.548	-2.203	4.342e-02	0.538	-3.922	ST7	suppression of tumorigenicity 7	7	116380616, 116380616	NM_018412	7982	7q31.1-q31.3	Hs.368131	21	membrane integral to membrane
201987_at	-0.223	9.704	-2.203	4.343e-02	0.538	-3.922	MED13	mediator complex subunit 13	17	-57374747	AI984051	9969	17q22-q23	Hs.282678	26	receptor activity nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
201074_at	-0.295	6.544	-2.203	4.344e-02	0.538	-3.922	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	3	-47602381	AA593983	6599	3p23-p21	Hs.476179	39	chromatin DNA binding chromatin binding transcription coactivator activity intracellular nucleus nucleoplasm chromatin assembly or disassembly chromatin remodeling regulation of transcription from RNA polymerase II promoter protein C-terminus binding organ morphogenesis SWI/SNF complex regulation of transcription positive regulation of transcription, DNA-dependent protein N-terminus binding
201742_x_at	-0.635	6.844	-2.203	4.344e-02	0.538	-3.922	SFRS1	splicing factor, arginine/serine-rich 1	17	-53433278	NM_006924	6426	17q21.3-q22	Hs.68714	106	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex cytoplasm mRNA splice site selection RNA splicing nuclear speck
1566701_at	-0.184	4.492	-2.203	4.345e-02	0.538	-3.922	VRK3	vaccinia related kinase 3	19	-55171535	AK074461	51231	19q13	Hs.443330	7	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
210095_s_at	0.391	6.516	2.202	4.346e-02	0.538	-3.922	IGFBP3	insulin-like growth factor binding protein 3	7	-45918368	M31159	3486	7p13-p12	Hs.450230 Hs.697535	324	regulation of cell growth osteoblast differentiation negative regulation of protein amino acid phosphorylation extracellular region nucleus protein tyrosine phosphatase activator activity negative regulation of signal transduction negative regulation of smooth muscle cell migration insulin-like growth factor binding protein complex insulin-like growth factor I binding positive regulation of apoptosis positive regulation of myoblast differentiation metal ion binding negative regulation of smooth muscle cell proliferation	p53 signaling pathway
223741_s_at	0.227	6.628	2.202	4.348e-02	0.538	-3.923	TTYH2	tweety homolog 2 (Drosophila)	17	69721290, 69756099	BC004233	94015	17q25.1	Hs.27935	8	ion channel activity chloride channel activity calcium ion binding protein binding plasma membrane ion transport integral to membrane chloride ion binding chloride channel complex
203684_s_at	-0.459	5.618	-2.202	4.352e-02	0.538	-3.924	BCL2	B-cell CLL/lymphoma 2	18	-59136166, -58941558	M13994	596	18q21.3 18q21.33	Hs.150749	705	G1/S transition of mitotic cell cycle protein phosphatase type 2A complex cell morphogenesis response to acid ovarian follicle development ureteric bud development branching involved in ureteric bud morphogenesis behavioral fear response response to hypoxia B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development renal system process intracellular membrane fraction nucleus cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol calcineurin complex protein amino acid dephosphorylation melanin metabolic process oxygen and reactive oxygen species metabolic process regulation of nitrogen utilization anti-apoptosis humoral immune response response to oxidative stress actin filament organization female pregnancy cell aging response to nutrient transcription factor binding cell death positive regulation of cell proliferation male gonad development activation of pro-apoptotic gene products response to radiation response to heat response to external stimulus response to toxin post-embryonic development organ morphogenesis response to inorganic substance response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration membrane integral to membrane cell-cell adhesion transcription activator activity peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis hemopoiesis negative regulation of ossification negative regulation of cell growth negative regulation of cell migration response to caffeine hair follicle morphogenesis axon regeneration regulation of protein stability nuclear membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization negative regulation of myeloid cell apoptosis T cell differentiation in the thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine stimulus response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation response to drug response to hydrogen peroxide protein homodimerization activity T cell homeostasis positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment response to peptide hormone stimulus regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis ear development response to estrogen stimulus regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability protein heterodimerization activity focal adhesion formation positive regulation of pigmentation during development spleen development thymus development gut morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue response to glucocorticoid stimulus BH3 domain binding defense response to virus regulation of cell cycle response to protein stimulus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport apoptosis in response to endoplasmic reticulum stress	Apoptosis Focal adhesion Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Prostate cancer Small cell lung cancer
233341_s_at	0.268	5.719	2.201	4.359e-02	0.539	-3.925	POLR1B	polymerase (RNA) I polypeptide B, 128kDa	2	113015962	AK025574	84172	2q13	Hs.86337	21	DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm nucleolus transcription zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
214252_s_at	0.303	5.333	2.199	4.373e-02	0.540	-3.928	CLN5	ceroid-lipofuscinosis, neuronal 5	13	76464059	AV700514	1203	13q21.1-q32	Hs.30213	19	protein binding lysosomal membrane vacuolar lumen endoplasmic reticulum Golgi apparatus lysosomal lumen acidification brain development visual perception integral to membrane integral to membrane neurogenesis protein catabolic process neuron maturation perinuclear region of cytoplasm	Lysosome
219737_s_at	-0.540	5.413	-2.199	4.374e-02	0.540	-3.928	PCDH9	protocadherin 9	13	-65774967	AI524125	5101	13q14.3-q21.1	Hs.654709 Hs.719302	8	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
225425_s_at	0.339	9.587	2.199	4.375e-02	0.540	-3.928	MRPL41	mitochondrial ribosomal protein L41	9	139566129	AV726260	64975	9q34.3	Hs.44017	10	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation apoptosis cell cycle
203394_s_at	-0.918	7.645	-2.199	4.377e-02	0.540	-3.928	HES1	hairy and enhancer of split 1, (Drosophila)	3	195336627	BE973687	3280	3q28-q29	Hs.250666	44	in utero embryonic development liver development DNA binding nucleus cytoplasm regulation of transcription, DNA-dependent cell adhesion positive regulation of cell proliferation positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter transcription repressor activity midbrain-hindbrain boundary morphogenesis oculomotor nerve development trochlear nerve development hindbrain morphogenesis neural tube development pituitary gland development lung development midbrain development auditory receptor cell fate determination cell fate commitment negative regulation of auditory receptor cell differentiation negative regulation of neuron differentiation cell maturation cell morphogenesis involved in neuron differentiation regulation of neurogenesis regulation of timing of neuron differentiation	Notch signaling pathway Maturity onset diabetes of the young
219253_at	-0.358	5.031	-2.198	4.379e-02	0.540	-3.929	TMEM185B	transmembrane protein 185B (pseudogene)	2	-120695323	NM_024121	79134	2q14.2	Hs.376722	5	membrane integral to membrane
217140_s_at	-0.460	10.886	-2.198	4.380e-02	0.540	-3.929	VDAC1	voltage-dependent anion channel 1	5	-133335505	AJ002428	7416	5q31	Hs.519320 Hs.709372	73	behavioral fear response protein binding mitochondrion mitochondrial outer membrane mitochondrial inner membrane plasma membrane anion transport apoptosis nerve-nerve synaptic transmission learning voltage-gated anion channel activity voltage-gated anion channel activity mitochondrial nucleoid interspecies interaction between organisms pore complex	Calcium signaling pathway Parkinson's disease Huntington's disease
217843_s_at	-0.259	7.886	-2.198	4.381e-02	0.540	-3.929	MED4	mediator complex subunit 4	13	-47548092	NM_014166	29079	13q14.2	Hs.181112	21	transcription cofactor activity receptor activity protein binding nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription activator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription thyroid hormone receptor binding
218652_s_at	0.264	6.682	2.198	4.382e-02	0.540	-3.929	PIGG	phosphatidylinositol glycan anchor biosynthesis, class G	4	482988	NM_017733	54872	4p16.3	Hs.7099	8	protein binding endoplasmic reticulum endoplasmic reticulum membrane metabolic process membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity phosphotransferase activity, for other substituted phosphate groups CP2 mannose-ethanolamine phosphotransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
215377_at	-0.220	5.267	-2.198	4.383e-02	0.540	-3.930	CTBP2	C-terminal binding protein 2	10	-126666407, -126666407, -126666407	AK024129	1488	10q26.13	Hs.501345	32	nucleus negative regulation of cell proliferation oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor viral genome replication cell junction synapse cofactor binding NAD or NADH binding oxidation reduction	Wnt signaling pathway Notch signaling pathway Pathways in cancer Chronic myeloid leukemia
212286_at	-0.412	5.053	-2.198	4.385e-02	0.540	-3.930	ANKRD12	ankyrin repeat domain 12	18	9126757	AW572909	23253	18p11.22	Hs.464585	7	nucleus
202850_at	-0.320	9.111	-2.198	4.387e-02	0.540	-3.930	ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	1	94656520, 94656520	NM_002858	5825	1p22-p21	Hs.700576	25	nucleotide binding protein binding ATP binding peroxisome peroxisomal membrane integral to peroxisomal membrane transport peroxisome organization peroxisomal long-chain fatty acid import membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters
225875_s_at	0.411	5.897	2.197	4.389e-02	0.540	-3.931	NIPAL3	NIPA-like domain containing 3	1	24614831	T84558	57185	1p36.12-p35.1	Hs.523442	6	membrane integral to membrane
226367_at	-0.207	2.972	-2.197	4.389e-02	0.540	-3.931	KDM5A	lysine (K)-specific demethylase 5A	12	-259483	AA854032	5927	12p11	Hs.76272	25	transcription factor activity iron ion binding protein binding intracellular nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter multicellular organismal development zinc ion binding oxidoreductase activity transcription activator activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cyclin-dependent protein kinase activating kinase holoenzyme complex positive regulation of transcription metal ion binding oxidation reduction
214022_s_at	0.443	8.409	2.197	4.394e-02	0.541	-3.932	IFITM1	interferon induced transmembrane protein 1 (9-27)	11	303990	AA749101	8519	11p15.5	Hs.458414	16	receptor signaling protein activity protein binding plasma membrane cell surface receptor linked signal transduction negative regulation of cell proliferation response to biotic stimulus integral to membrane	B cell receptor signaling pathway
226149_at	0.227	5.998	2.197	4.395e-02	0.541	-3.932	SNHG11	small nucleolar RNA host gene 11 (non-protein coding)	20	36508710	AW661805	128439	20q11.23	Hs.16936	2
208633_s_at	-0.314	6.467	-2.196	4.396e-02	0.541	-3.932	MACF1	microtubule-actin crosslinking factor 1	1	39319704, 39569396	W61052	23499	1p32-p31	Hs.580782	25	calcium ion binding calcium ion binding protein binding cytoplasm cytoplasm cytoskeleton cytoskeleton cell cycle arrest microtubule binding biological_process actin filament binding
202241_at	-0.671	8.827	-2.196	4.398e-02	0.541	-3.933	TRIB1	tribbles homolog 1 (Drosophila)	8	126511744	NM_025195	10221	8q24.13	Hs.444947	19	protein kinase activity protein kinase inhibitor activity ATP binding nucleus cytoplasm protein amino acid phosphorylation negative regulation of protein kinase activity JNK cascade transcription factor binding negative regulation of smooth muscle cell migration mitogen-activated protein kinase kinase binding negative regulation of lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide regulation of MAP kinase activity negative regulation of transcription factor activity negative regulation of smooth muscle cell proliferation
204414_at	-0.195	2.852	-2.196	4.401e-02	0.541	-3.933	LARGE	like-glycosyltransferase	22	-31999061	NM_004737	9215	22q12.3	Hs.474667	18	Golgi apparatus N-acetylglucosamine metabolic process protein amino acid glycosylation glycosphingolipid biosynthetic process acetylglucosaminyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane muscle maintenance
1564285_at	-0.267	2.810	-2.196	4.402e-02	0.541	-3.933	HFM1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)	1	-91498910	AK096330	164045	1p22.2	Hs.454818	3	nucleotide binding nucleic acid binding helicase activity ATP binding ATP-dependent helicase activity hydrolase activity
241709_s_at	-0.220	4.830	-2.195	4.405e-02	0.541	-3.934	DOCK1	dedicator of cytokinesis 1	10	128584012	AA599017	1793	10q26.13-q26.3	Hs.159195 Hs.645702	39	guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm phagocytosis, engulfment apoptosis signal transduction integrin-mediated signaling pathway small GTPase mediated signal transduction membrane SH3 domain binding	Focal adhesion Regulation of actin cytoskeleton
228352_at	-0.193	5.160	-2.195	4.405e-02	0.541	-3.934	UNC13D	unc-13 homolog D (C. elegans)	17	-71334901	AW189167	201294	17q25.1	Hs.41045	21	granuloma formation germinal center formation cytoplasm exocytosis phagocytosis membrane natural killer cell degranulation defense response to virus
1567628_at	0.210	4.600	2.195	4.406e-02	0.541	-3.934	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	5	-149761394, -149761392	M28590	972	5q32	Hs.436568	58	prostaglandin biosynthetic process intracellular protein complex assembly intracellular protein transport immune response signal transduction cell proliferation membrane integral to membrane immunoglobulin mediated immune response antigen processing and presentation of endogenous antigen cytokine binding MHC class II protein binding identical protein binding regulation of macrophage activation negative regulation of apoptosis T cell selection	Antigen processing and presentation
211009_s_at	-0.415	6.617	-2.195	4.407e-02	0.541	-3.934	ZNF271	zinc finger protein 271	18	31124233	AF159567	10778	18q12	Hs.718598 Hs.718962	6
206057_x_at	-0.551	5.591	-2.195	4.409e-02	0.541	-3.935	SPN	sialophorin	16	29581800, 29582080	NM_003123	6693	16p11.2	Hs.632188	44	response to protozoan negative regulation of type IV hypersensitivity uropod transmembrane receptor activity protein binding basement membrane extracellular space integral to plasma membrane chemotaxis cellular defense response negative regulation of cell adhesion establishment or maintenance of cell polarity cell surface receptor linked signal transduction bacterial binding induction of apoptosis by extracellular signals external side of plasma membrane membrane T cell costimulation positive regulation of T cell proliferation negative regulation of T cell proliferation positive regulation of tumor necrosis factor biosynthetic process defense response to bacterium negative thymic T cell selection regulation of defense response to virus regulation of immune response	Cell adhesion molecules (CAMs)
1554360_at	0.240	3.351	2.195	4.411e-02	0.541	-3.935	FCHSD2	FCH and double SH3 domains 2	11	-72225437	BC010394	9873	11q13.4	Hs.577053	9	protein binding
212269_s_at	0.274	7.658	2.194	4.414e-02	0.541	-3.936	MCM3AP	minichromosome maintenance complex component 3 associated protein	21	-46479475	AJ010089	8888	21q22.3	Hs.389037	19	DNA binding nucleus cytoplasm cytosol DNA replication protein import into nucleus
229360_at	0.372	4.243	2.194	4.415e-02	0.541	-3.936	ZNF280B	zinc finger protein 280B	22	-21168771	N22886	140883	22q11.22	Hs.43834	6	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
230425_at	-0.656	5.422	-2.194	4.415e-02	0.541	-3.936	EPHB1	EPH receptor B1	3	135996949	AI674183	2047	3q21-q23	Hs.116092	41	nucleotide binding receptor activity ephrin receptor activity protein binding ATP binding plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway nervous system development transferase activity	Axon guidance
210139_s_at	-0.518	8.473	-2.194	4.415e-02	0.541	-3.936	PMP22	peripheral myelin protein 22	17	-15073821, -15073821, -15073820	L03203	5376	17p12-p11.2	Hs.372031	107	synaptic transmission peripheral nervous system development membrane integral to membrane myelin assembly
206756_at	0.307	5.148	2.194	4.420e-02	0.542	-3.937	CHST7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	X	46318135	NM_019886	56548	Xp11.23	Hs.129955	10	Golgi membrane N-acetylglucosamine 6-O-sulfotransferase activity Golgi apparatus polysaccharide metabolic process N-acetylglucosamine metabolic process sulfur metabolic process chondroitin 6-sulfotransferase activity membrane integral to membrane integral to membrane transferase activity chondroitin sulfate biosynthetic process	Chondroitin sulfate biosynthesis
229764_at	-1.526	4.095	-2.193	4.423e-02	0.542	-3.937	TPRG1	tumor protein p63 regulated 1	3	190372456	AW629527	285386	3q28	Hs.338851	4	cytoplasm
217984_at	0.266	6.335	2.193	4.425e-02	0.542	-3.938	RNASET2	ribonuclease T2	6	-167262993	NM_003730	8635	6q27	Hs.529989	11	RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity
200737_at	-0.490	8.965	-2.192	4.430e-02	0.542	-3.939	PGK1	phosphoglycerate kinase 1	X	77246321	NM_000291	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
201754_at	0.161	12.249	2.192	4.432e-02	0.542	-3.939	COX6C	cytochrome c oxidase subunit VIc	8	-100959547	NM_004374	1345	8q22-q23	Hs.351875	10	cytochrome-c oxidase activity mitochondrion mitochondrial inner membrane generation of precursor metabolites and energy membrane integral to membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
211779_x_at	0.210	6.385	2.192	4.433e-02	0.542	-3.939	AP2A2	adaptor-related protein complex 2, alpha 2 subunit	11	915840	BC006155	161	11p15.5	Hs.19121	41	protein binding cytosol plasma membrane plasma membrane coated pit intracellular protein transport endocytosis lipid binding protein transporter activity membrane coat AP-2 adaptor complex regulation of defense response to virus by virus	Endocytosis Huntington's disease
229060_at	0.471	5.616	2.192	4.434e-02	0.542	-3.940	YPEL2	yippee-like 2 (Drosophila)	17	54763834	AW005748	388403	17q22	Hs.463613	5	nucleus nucleolus
212482_at	-0.453	8.151	-2.192	4.435e-02	0.542	-3.940	RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	2	86800924	BF671894	64795	2p11.2	Hs.75277	7
1565483_at	0.423	7.780	2.192	4.437e-02	0.542	-3.940	EGFR	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	7	55054218, 55054218, 55054218, 55054218	AF277897	1956	7p12	Hs.488293	1458	nucleotide binding cell morphogenesis ossification double-stranded DNA binding MAP/ERK kinase kinase activity transmembrane receptor activity epidermal growth factor receptor activity epidermal growth factor receptor activity ATP binding extracellular region extracellular space intracellular nucleus cytoplasm endosome plasma membrane plasma membrane response to stress cell surface receptor linked signal transduction epidermal growth factor receptor signaling pathway activation of phospholipase C activity salivary gland morphogenesis integral to membrane basolateral plasma membrane cell-cell adhesion transferase activity protein phosphatase binding AP-2 adaptor complex endocytic vesicle nitric-oxide synthase regulator activity positive regulation of cell migration positive regulation of cyclin-dependent protein kinase activity during G1/S positive regulation of phosphorylation identical protein binding activation of phospholipase A2 activity by calcium-mediated signaling positive regulation of MAP kinase activity positive regulation of nitric oxide biosynthetic process protein amino acid autophosphorylation protein heterodimerization activity positive regulation of epithelial cell proliferation regulation of peptidyl-tyrosine phosphorylation regulation of nitric-oxide synthase activity actin filament binding protein insertion into membrane response to UV-A Shc-EGFR complex	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interaction Endocytosis Dorso-ventral axis formation Focal adhesion Adherens junction Gap junction Regulation of actin cytoskeleton GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Non-small cell lung cancer
228448_at	0.184	4.154	2.192	4.437e-02	0.542	-3.940	MAP6	microtubule-associated protein 6	11	-74991552, -74975610	AL134650	4135	11q13.5	Hs.585540	12	calmodulin binding cytoplasm Golgi apparatus cytoskeleton microtubule
212131_at	-0.386	8.418	-2.191	4.439e-02	0.542	-3.940	LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)	19	39355191	BG054966	26065	19q13.11	Hs.718430	6
224150_s_at	0.405	5.950	2.191	4.439e-02	0.542	-3.940	CEP70	centrosomal protein 70kDa	3	-139695876	AF289495	80321	3q22-q23	Hs.531962	9	protein binding centrosome
1564838_a_at	0.218	3.523	2.191	4.439e-02	0.542	-3.941	LOC151760	hypothetical LOC151760	3		BC038577	151760	3q13.13	Hs.124136	1
200769_s_at	-0.364	6.068	-2.191	4.441e-02	0.542	-3.941	MAT2A	methionine adenosyltransferase II, alpha	2	85619798	NM_005911	4144	2p11.2	Hs.516157	18	nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
219882_at	-0.309	5.188	-2.191	4.443e-02	0.542	-3.941	TTLL7	tubulin tyrosine ligase-like family, member 7	1	-84107644	NM_024686	79739	1p31.1	Hs.445826	7	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process multicellular organismal development nervous system development ligase activity cell differentiation dendrite perikaryon
232898_at	0.264	4.807	2.191	4.445e-02	0.542	-3.942	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	5	-39407536	R79120	1601	5p13	Hs.481980	47	coated pit protein C-terminus binding cell proliferation membrane clathrin coated vesicle membrane cytoplasmic vesicle	Endocytosis
221143_at	-0.505	4.456	-2.190	4.447e-02	0.542	-3.942	RPA4	replication protein A4, 34kDa	X	96025667	NM_013347	29935	Xq21.33	Hs.659349	9	nucleic acid binding single-stranded DNA binding nucleus DNA replication factor A complex DNA replication DNA replication initiation	DNA replication Nucleotide excision repair Mismatch repair Homologous recombination
206329_at	0.397	6.287	2.190	4.449e-02	0.542	-3.942	EXTL1	exostoses (multiple)-like 1	1	26220857	NM_004455	2134	1p36.1	Hs.150956	11	skeletal system development protein binding endoplasmic reticulum membrane integral to membrane transferase activity, transferring hexosyl groups intrinsic to endoplasmic reticulum membrane glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Heparan sulfate biosynthesis Metabolic pathways
1553185_at	-0.390	9.804	-2.190	4.450e-02	0.542	-3.943	RASEF	RAS and EF-hand domain containing	9	-84787136	NM_152573	158158	9q21.32	Hs.657750	3	nucleotide binding calcium ion binding GTP binding cytoplasm small GTPase mediated signal transduction protein transport perinuclear region of cytoplasm
228601_at	0.234	4.627	2.190	4.451e-02	0.542	-3.943	LOC401022	hypothetical LOC401022	2		AW340112	401022	2q31.2	Hs.98661	1
236866_at	0.237	4.787	2.190	4.451e-02	0.542	-3.943	GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase	16	-87407642	AA884446	2588	16q24.3	Hs.271383	39	N-acetylgalactosamine-4-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process N-acetylgalactosamine-6-sulfatase activity	Glycosaminoglycan degradation Metabolic pathways Lysosome
201146_at	-0.330	8.217	-2.190	4.452e-02	0.542	-3.943	NFE2L2	nuclear factor (erythroid-derived 2)-like 2	2	-177803279, -177803278	NM_006164	4780	2q31	Hs.715540	141	transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity
213803_at	-0.304	7.794	-2.190	4.453e-02	0.542	-3.943	KPNB1	karyopherin (importin) beta 1	17	43082273	BG545463	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
201051_at	0.250	9.005	2.189	4.455e-02	0.542	-3.944	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	15	-66857930	BE560202	8125	15q22.3-q23	Hs.458747	44	protein binding nucleus cytoplasm endoplasmic reticulum nucleocytoplasmic transport nucleocytoplasmic transport intracellular signaling cascade regulation of transcription perinuclear region of cytoplasm
232708_at	0.196	4.261	2.189	4.457e-02	0.542	-3.944	GALT	galactose-1-phosphate uridylyltransferase	9	34636634	AA453223	2592	9p13	Hs.522090	72	iron ion binding cytosol carbohydrate metabolic process galactose metabolic process UDP-glucose:hexose-1-phosphate uridylyltransferase activity UDP-glucose:hexose-1-phosphate uridylyltransferase activity zinc ion binding transferase activity nucleotidyltransferase activity metal ion binding	Galactose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
218537_at	-0.647	8.793	-2.189	4.459e-02	0.542	-3.944	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)	16	-3012626	NM_017885	54985	16p13.3	Hs.719259	2	nucleus cytoplasm
201669_s_at	0.389	7.646	2.189	4.462e-02	0.542	-3.945	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	NM_002356	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
211979_at	-0.215	6.652	-2.188	4.465e-02	0.542	-3.946	GPR107	G protein-coupled receptor 107	9	131855805	AB046844	57720	9q34.11	Hs.512461	7	membrane integral to membrane
221879_at	0.896	4.667	2.188	4.466e-02	0.542	-3.946	CALML4	calmodulin-like 4	15	-66270096	AA886335	91860	15q23	Hs.709550	4	calcium ion binding
1563511_at	0.354	5.231	2.188	4.468e-02	0.543	-3.946	DKFZp451B082	hypothetical gene supported by AL831931	6		AL831931	401282	6q26	Hs.444817
220967_s_at	-0.154	5.572	-2.187	4.475e-02	0.543	-3.947	ZNF696	zinc finger protein 696	8	144444933	NM_030895	79943	8q24.3	Hs.512740	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
208945_s_at	-0.310	8.493	-2.187	4.477e-02	0.543	-3.948	BECN1	beclin 1, autophagy related	17	-38215675	NM_003766	8678	17q21	Hs.716464	56	protein binding cytoplasm Golgi apparatus trans-Golgi network autophagy anti-apoptosis cellular defense response negative regulation of cell proliferation response to virus membrane cytoplasmic membrane-bounded vesicle positive regulation of macroautophagy protein complex	Regulation of autophagy
208709_s_at	-0.236	9.962	-2.187	4.479e-02	0.543	-3.948	NRD1	nardilysin (N-arginine dibasic convertase)	1	-52027453	U64898	4898	1p32.2-p32.1	Hs.584782	18	metalloendopeptidase activity protein binding cytosol proteolysis neuromuscular junction development peptidase activity zinc ion binding cell proliferation cell surface cell migration metal ion binding epidermal growth factor binding positive regulation of membrane protein ectodomain proteolysis regulation of endopeptidase activity
226486_at	0.334	5.870	2.186	4.481e-02	0.543	-3.948	MTERFD2	MTERF domain containing 2	2	-241683654, -241675182	AA115760	130916	2q37.3	Hs.159556	5
242149_at	-0.449	6.084	-2.186	4.481e-02	0.543	-3.949	C18orf19	chromosome 18 open reading frame 19	18	-13653345	R02709	125228	18p11.21	Hs.13034	3	membrane integral to membrane
1552899_at	0.333	4.863	2.186	4.485e-02	0.543	-3.949	RP4-662A9.2	hypothetical protein MGC34034	6	134183977	NM_153224	154089	6q23.2	Hs.126165	1
204629_at	0.247	6.712	2.186	4.486e-02	0.543	-3.949	PARVB	parvin, beta	22	42726505, 42751500	NM_013327	29780	22q13.2-q13.33	Hs.475074	18	actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion cell junction	Focal adhesion
207345_at	0.213	3.767	2.186	4.487e-02	0.543	-3.950	FST	follistatin	5	52812351	NM_006350	10468	5q11.2	Hs.9914	47	negative regulation of transcription from RNA polymerase II promoter signal transducer activity protein binding extracellular region multicellular organismal development negative regulation of follicle-stimulating hormone secretion positive regulation of hair follicle development	TGF-beta signaling pathway
244721_at	0.209	4.696	2.186	4.487e-02	0.543	-3.950	TP53INP1	tumor protein p53 inducible nuclear protein 1	8	-96007376	AW242000	94241	8q22	Hs.492261	16	nucleus apoptosis
204794_at	-0.238	5.226	-2.186	4.487e-02	0.543	-3.950	DUSP2	dual specificity phosphatase 2	2	-96172634	NM_004418	1844	2q11	Hs.1183	16	inactivation of MAPK activity protein tyrosine phosphatase activity nucleus protein amino acid dephosphorylation protein tyrosine/threonine phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity mitogen-activated protein kinase binding	MAPK signaling pathway
224600_at	-0.427	6.679	-2.185	4.490e-02	0.543	-3.950	CGGBP1	CGG triplet repeat binding protein 1	3	-88183789	BE501318	8545	3p12-p11.1	Hs.444818	14	DNA binding double-stranded DNA binding nucleus regulation of transcription
238034_at	0.269	6.690	2.185	4.491e-02	0.543	-3.950	CANX	calnexin	5	179058535	AI890021	821	5q35	Hs.699155	90	calcium ion binding sugar binding endoplasmic reticulum protein folding protein secretion membrane integral to membrane melanosome unfolded protein binding	Antigen processing and presentation
212381_at	-0.592	6.939	-2.185	4.493e-02	0.543	-3.951	USP24	ubiquitin specific peptidase 24	1	-55304619	BF444943	23358	1p32.3	Hs.477009	13	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
219807_x_at	0.172	6.340	2.185	4.493e-02	0.543	-3.951	RAB4B	RAB4B, member RAS oncogene family	19	45976010	NM_016154	53916	19q13.2	Hs.631539	5	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
210088_x_at	0.226	6.645	2.185	4.494e-02	0.543	-3.951	MYL4	myosin, light chain 4, alkali; atrial, embryonic	17	42641426, 42641712	M36172	4635	17q21-qter	Hs.463300	21	regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex muscle organ development structural constituent of muscle myosin complex A band myosin II heavy chain binding positive regulation of ATPase activity actin filament binding cardiac muscle contraction	Cardiac muscle contraction
221816_s_at	0.301	7.470	2.185	4.496e-02	0.543	-3.951	PHF11	PHD finger protein 11	13	48967801, 48968528	BF055474	51131	13q14.2	Hs.369039	17	protein binding zinc ion binding metal ion binding
218084_x_at	0.239	6.036	2.185	4.496e-02	0.543	-3.951	FXYD5	FXYD domain containing ion transport regulator 5	19	40337466	NM_014164	53827	19q12-q13.1	Hs.333418	20	actin binding ion channel activity ion transport membrane integral to membrane microvillus assembly cadherin binding negative regulation of calcium-dependent cell-cell adhesion
204806_x_at	0.285	8.027	2.184	4.499e-02	0.543	-3.952	HLA-F	major histocompatibility complex, class I, F	6	29799095, 29799095, 1143812, 1143812, 945922, 945922	NM_018950	3134	6p21.3	Hs.519972	68	antigen processing and presentation of peptide antigen via MHC class I immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
212641_at	-0.338	6.102	-2.184	4.502e-02	0.543	-3.953	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	6	-143114296	AL023584	3097	6q23-q24	Hs.510172	10	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200835_s_at	-0.348	8.763	-2.184	4.503e-02	0.543	-3.953	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AI553791	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
233322_at	0.216	5.124	2.183	4.507e-02	0.543	-3.954	CD9	CD9 molecule	12	6179815	AK025016	928	12p13.3	Hs.114286	96	protein binding plasma membrane plasma membrane integral to plasma membrane cell motion cell adhesion fusion of sperm to egg plasma membrane platelet activation paranodal junction assembly platelet alpha granule membrane	Hematopoietic cell lineage
214449_s_at	-0.329	9.179	-2.183	4.508e-02	0.543	-3.954	RHOQ	ras homolog gene family, member Q	2	46623370	NM_012249	23433	2p21	Hs.709193	27	nucleotide binding GTPase activity profilin binding GTP binding intracellular cytoplasm actin filament plasma membrane GTP catabolic process small GTPase mediated signal transduction insulin receptor signaling pathway regulation of cell shape positive regulation of specific transcription from RNA polymerase II promoter cortical actin cytoskeleton organization GBD domain binding regulation of actin cytoskeleton organization membrane raft positive regulation of glucose import positive regulation of filopodium assembly regulation of establishment of protein localization	Insulin signaling pathway
221467_at	0.167	4.486	2.183	4.508e-02	0.543	-3.954	MC4R	melanocortin 4 receptor	18	-56189543	NM_005912	4160	18q22	Hs.532833	147	receptor activity G-protein coupled receptor activity melanocortin receptor activity protein binding cytoplasm plasma membrane signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger feeding behavior integral to membrane regulation of metabolic process insulin secretion response to insulin stimulus positive regulation of bone resorption	Neuroactive ligand-receptor interaction
48531_at	-0.307	7.471	-2.183	4.510e-02	0.543	-3.954	TNIP2	TNFAIP3 interacting protein 2	4	-2713184, -2713184	AA522816	79155	4p16.3	Hs.719161	20	protein binding cytoplasm I-kappaB kinase/NF-kappaB cascade
209510_at	-0.276	8.058	-2.183	4.510e-02	0.543	-3.954	RNF139	ring finger protein 139	8	125556188	AF064801	11236	8q24	Hs.492751	10	receptor activity protein binding endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process regulation of protein ubiquitination metal ion binding
225480_at	-0.187	8.439	-2.183	4.511e-02	0.543	-3.954	C1orf122	chromosome 1 open reading frame 122	1	38046059	BE408081	127687	1p34.3	Hs.532749	4
225912_at	0.403	6.663	2.183	4.512e-02	0.543	-3.954	TP53INP1	tumor protein p53 inducible nuclear protein 1	8	-96007376	AW341649	94241	8q22	Hs.492261	16	nucleus apoptosis
211274_at	-0.198	4.260	-2.183	4.512e-02	0.543	-3.954	TBX1	T-box 1	22	18124225, 18124225, 18124225	AF012130	6899	22q11.21	Hs.173984	21	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter heart development anatomical structure morphogenesis protein homodimerization activity sequence-specific DNA binding thymus development embryonic viscerocranium morphogenesis parathyroid gland development soft palate development pharyngeal system development
219990_at	0.853	6.845	2.183	4.513e-02	0.543	-3.955	E2F8	E2F transcription factor 8	11	-19202185	NM_024680	79733	11p15.1	Hs.523526	8	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle
237981_at	-0.559	9.606	-2.182	4.516e-02	0.543	-3.955	CMYA5	cardiomyopathy associated 5	5	79021414	AA195941	202333	5q14.1	Hs.482625	7	cytoplasm identical protein binding perinuclear region of cytoplasm
243614_s_at	-0.211	4.575	-2.182	4.521e-02	0.543	-3.956	PRODH2	proline dehydrogenase (oxidase) 2	19	-40982731	AW138125	58510	19q13.1	Hs.515366	2	proline dehydrogenase activity mitochondrial inner membrane glutamate biosynthetic process proline catabolic process oxidoreductase activity oxidation reduction	Arginine and proline metabolism Metabolic pathways
205758_at	0.237	4.613	2.182	4.521e-02	0.543	-3.956	CD8A	CD8a molecule	2	-86865239, -86865239	AW006735	925	2p12	Hs.85258	72	protein binding extracellular region plasma membrane integral to plasma membrane immune response transmembrane receptor protein tyrosine kinase signaling pathway coreceptor activity antigen processing and presentation T cell receptor complex T cell activation MHC class I protein binding	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage T cell receptor signaling pathway Primary immunodeficiency
210010_s_at	0.242	6.004	2.182	4.522e-02	0.543	-3.956	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	22	-17543094	U25147	6576	22q11.21	Hs.719167	11	transporter activity protein binding mitochondrion mitochondrial inner membrane transport mitochondrial citrate transport citrate transmembrane transporter activity membrane integral to membrane
218501_at	0.293	6.685	2.181	4.527e-02	0.544	-3.957	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	3	-56736485, -56736485, -56736485	NM_019555	50650	3p21-p13	Hs.476402	15	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction
231742_at	0.219	4.236	2.181	4.527e-02	0.544	-3.957	CRX	cone-rod homeobox	19	53016910	NM_000554	1406	19q13.3	Hs.617342 Hs.633434 Hs.639114	31	chromatin binding transcription factor activity protein binding nucleus transcription factor complex regulation of transcription, DNA-dependent visual perception circadian rhythm organ morphogenesis transcription activator activity sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter positive regulation of photoreceptor cell differentiation response to stimulus
220120_s_at	0.243	2.656	2.180	4.535e-02	0.544	-3.959	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A	5	-111526213	NM_022140	64097	5q22.1-q22.2	Hs.584954	7	binding cellular_component cytoplasm cytoskeleton cytoskeletal protein binding biological_process extrinsic to membrane
239051_at	0.211	4.112	2.180	4.536e-02	0.544	-3.959	FLJ31813	hypothetical protein FLJ31813	10		BF508908	326332	10q11.22	Hs.712902	1
208822_s_at	0.224	8.909	2.180	4.537e-02	0.544	-3.959	DAP3	death associated protein 3	1	153925497, 153925497	U18321	7818	1q21-q22	Hs.516746	26	protein binding mitochondrion mitochondrial ribosome ribosome induction of apoptosis by extracellular signals apoptotic mitochondrial changes small ribosomal subunit
204049_s_at	0.320	7.411	2.180	4.538e-02	0.544	-3.959	PHACTR2	phosphatase and actin regulator 2	6	143971009, 144040794	NM_014721	9749	6q24.2	Hs.102471	8	actin binding phosphoprotein phosphatase inhibitor activity protein binding
209121_x_at	0.238	7.887	2.180	4.538e-02	0.544	-3.959	NR2F2	nuclear receptor subfamily 2, group F, member 2	15	94670160, 94675114, 94676797, 94677572	M64497	7026	15q26	Hs.657455	27	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding
226682_at	-0.428	8.536	-2.180	4.539e-02	0.544	-3.960	RORA	RAR-related orphan receptor A	15	-58567776, -58567776, -58567776	AW006185	6095	15q22.2	Hs.560343 Hs.655155	33	transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding
217943_s_at	-0.364	8.997	-2.179	4.544e-02	0.544	-3.961	MAP7D1	MAP7 domain containing 1	1	36394389	NM_018067	55700	1p34.3	Hs.700595	7	spindle
242441_at	-0.313	5.294	-2.179	4.546e-02	0.544	-3.961	LOC646548	similar to ADAM metallopeptidase domain 21 preproprotein	14		AA608973	646548	14q24.2
1564166_s_at	0.254	4.847	2.179	4.549e-02	0.544	-3.961	PRKRIP1	PRKR interacting protein 1 (IL11 inducible)	7	101823808	AK098276	79706	7q22.1	Hs.406395	6	double-stranded RNA binding protein kinase inhibitor activity protein binding nucleus nucleolus negative regulation of protein kinase activity protein kinase binding negative regulation of phosphorylation
205628_at	-0.200	3.465	-2.179	4.549e-02	0.544	-3.962	PRIM2	primase, DNA, polypeptide 2 (58kDa)	6	57290380	NM_000947	5558	6p12-p11.1	Hs.654580	16	DNA binding DNA primase activity iron ion binding nucleoplasm alpha DNA polymerase:primase complex DNA replication DNA replication, synthesis of RNA primer transcription transferase activity nucleotidyltransferase activity metal ion binding 4 iron, 4 sulfur cluster binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication
211778_s_at	-0.252	4.053	-2.178	4.550e-02	0.544	-3.962	OVOL2	ovo-like 2 (Drosophila)	20	-17952795	BC006148	58495	20pter-q11.23	Hs.661013 Hs.710157	5	neural crest cell migration neural fold formation DNA binding intracellular nucleus heart development zinc ion binding negative regulation of cell proliferation dorsal/ventral pattern formation regulation of transcription negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding embryonic gut morphogenesis
235085_at	0.296	8.123	2.178	4.551e-02	0.544	-3.962	PRAGMIN	homolog of rat pragma of Rnd2	8	-8212667	BF739767	157285	8p23.1	Hs.657673	4	nucleotide binding non-membrane spanning protein tyrosine kinase activity ATP binding protein amino acid phosphorylation transferase activity
208382_s_at	0.254	5.108	2.178	4.551e-02	0.544	-3.962	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	22	-37244899	D63882	11144	22q13.1	Hs.339396	24	nucleotide binding pachytene condensed nuclear chromosome ovarian follicle development oocyte maturation DNA binding protein binding ATP binding intracellular nucleus cytoplasm DNA metabolic process cell cycle meiosis reciprocal meiotic recombination male meiosis I spermatogenesis spermatid development female gamete generation DNA-dependent ATPase activity nucleoside-triphosphatase activity
232986_at	0.239	3.869	2.178	4.554e-02	0.544	-3.962	ZNF233	zinc finger protein 233	19	49455915	AC074331	353355	19q13.31	Hs.466891	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207818_s_at	0.196	3.446	2.178	4.557e-02	0.544	-3.963	HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	10	-92490557	NM_000872	3363	10q21-q24	Hs.73739	35	receptor activity G-protein coupled receptor activity serotonin receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger synaptic transmission circadian rhythm blood circulation	Calcium signaling pathway Neuroactive ligand-receptor interaction
244431_at	0.251	4.779	2.177	4.559e-02	0.544	-3.963	KILLIN	killin protein	10	-89608897	AA057423	100144748	10q23	Hs.559820	2	DNA binding nucleus apoptosis cell cycle
208386_x_at	0.160	3.279	2.177	4.561e-02	0.545	-3.964	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	22	-37244899	NM_007068	11144	22q13.1	Hs.339396	24	nucleotide binding pachytene condensed nuclear chromosome ovarian follicle development oocyte maturation DNA binding protein binding ATP binding intracellular nucleus cytoplasm DNA metabolic process cell cycle meiosis reciprocal meiotic recombination male meiosis I spermatogenesis spermatid development female gamete generation DNA-dependent ATPase activity nucleoside-triphosphatase activity
231666_at	-0.454	5.277	-2.177	4.564e-02	0.545	-3.964	PAX3	paired box 3	2	-222866592, -222774675, -222772850	AA194168	5077	2q35 2q35-q37	Hs.42146	103	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter apoptosis multicellular organismal development sensory perception of sound organ morphogenesis sequence-specific DNA binding
219658_at	0.162	5.025	2.177	4.565e-02	0.545	-3.964	PTCD2	pentatricopeptide repeat domain 2	5	71651955	NM_024754	79810	5q13.2	Hs.126906	3	kidney development liver development mitochondrion organization heart development muscle fiber development regulation of mRNA processing ventricular cardiac muscle morphogenesis
227087_at	0.301	6.974	2.177	4.566e-02	0.545	-3.965	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	2	98427752, 98427752	AA126419	3631	2q11.2	Hs.469386	16	signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
1557067_s_at	-0.293	6.063	-2.176	4.571e-02	0.545	-3.966	LUC7L	LUC7-like (S. cerevisiae)	16	-178974, -178970	AI744735	55692	16p13.3	Hs.16803	11	protein binding nucleus zinc ion binding negative regulation of striated muscle development metal ion binding RS domain binding
223331_s_at	-0.207	6.417	-2.176	4.573e-02	0.545	-3.966	DDX20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	1	112099776	AF106019	11218	1p21.1-p13.2	Hs.591405	30	negative regulation of transcription from RNA polymerase II promoter nucleotide binding assembly of spliceosomal tri-snRNP DNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus nucleoplasm spliceosomal complex cytoplasm cytosol cytoskeleton mRNA processing induction of apoptosis RNA splicing Cajal body transcription repressor activity hydrolase activity transcriptional repressor complex
225222_at	-0.307	6.958	-2.175	4.576e-02	0.545	-3.967	HIAT1	hippocampus abundant transcript 1	1	100276376	AI243268	64645	1p21.2	Hs.124156	5	transporter activity transport tetracycline:hydrogen antiporter activity tetracycline transport membrane integral to membrane response to antibiotic
211269_s_at	0.288	3.634	2.175	4.577e-02	0.545	-3.967	IL2RA	interleukin 2 receptor, alpha	10	-6093511	K03122	3559	10p15-p14	Hs.231367	189	receptor activity interleukin-2 receptor activity plasma membrane apoptosis immune response cell surface receptor linked signal transduction cell proliferation integral to membrane	Cytokine-cytokine receptor interaction Endocytosis Jak-STAT signaling pathway Hematopoietic cell lineage
232001_at	-0.457	8.457	-2.175	4.580e-02	0.545	-3.967	LOC439949	hypothetical protein LOC439949	10		AW193600	439949	10p14	Hs.590987	2
1552860_at	-0.241	3.677	-2.175	4.584e-02	0.546	-3.968	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)	18	-42808570, -42802655	NM_145653	162699	18q21.1	Hs.515381 Hs.631674	4	DNA binding protein binding nucleus integral to membrane transcription regulator activity regulation of transcription
222777_s_at	0.199	4.541	2.174	4.586e-02	0.546	-3.968	WHSC1	Wolf-Hirschhorn syndrome candidate 1	4	1842920, 1864306, 1864306, 1864306, 1872150	AI770166	7468	4p16.3	Hs.113876	32	DNA binding protein binding nucleus cytoplasm methyltransferase activity zinc ion binding anatomical structure morphogenesis chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription metal ion binding	Lysine degradation
1553281_at	0.142	5.130	2.174	4.586e-02	0.546	-3.968	PLCXD2	phosphatidylinositol-specific phospholipase C, X domain containing 2	3	112876196, 112876196	NM_153268	257068	3q13.2	Hs.655022	2	phospholipase C activity signal transducer activity intracellular signaling cascade lipid catabolic process hydrolase activity
216320_x_at	0.200	6.099	2.174	4.587e-02	0.546	-3.969	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	3	-49696384	U37055	4485	3p21	Hs.349110 Hs.512587	31	catalytic activity serine-type endopeptidase activity calcium ion binding extracellular region proteolysis blood coagulation biological_process
224853_at	0.344	6.048	2.174	4.589e-02	0.546	-3.969	SLAIN2	SLAIN motif family, member 2	4	48038369	AI979301	57606	4p11	Hs.479677	5
203442_x_at	0.233	5.518	2.174	4.590e-02	0.546	-3.969	EML3	echinoderm microtubule associated protein like 3	11	-62126266	AA478965	256364	11q12.3	Hs.379785	8	protein binding cytoplasm microtubule
1559890_a_at	-0.164	2.110	-2.174	4.591e-02	0.546	-3.969	ABI1	abl-interactor 1	10	-27075530	BF194851	10006	10p11.2	Hs.508148	39	intracellular soluble fraction nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal protein binding negative regulation of cell proliferation peptidyl-tyrosine phosphorylation synaptosome lamellipodium cell junction filopodium growth cone synapse
244871_s_at	-0.222	5.364	-2.173	4.597e-02	0.546	-3.970	USP32	ubiquitin specific peptidase 32	17	-55609472	AW268357	84669	17q23.1-q23.2	Hs.132868	6	ubiquitin thiolesterase activity calcium ion binding ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity membrane
223449_at	0.309	6.406	2.173	4.597e-02	0.546	-3.971	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	5	-115807149	AF225425	57556	5q23.1	Hs.156967	11	receptor activity protein binding apoptosis cytoskeleton organization cell surface receptor linked signal transduction multicellular organismal development nervous system development axon guidance organ morphogenesis membrane integral to membrane cell differentiation axon	Axon guidance
224046_s_at	-0.847	5.283	-2.172	4.603e-02	0.547	-3.972	PDE7A	phosphodiesterase 7A	8	-66796607, -66792459	U67932	5150	8q13	Hs.527119	16	cell fraction 3',5'-cyclic-AMP phosphodiesterase activity signal transduction hydrolase activity	Purine metabolism
226455_at	-0.275	5.550	-2.172	4.604e-02	0.547	-3.972	CREB3L4	cAMP responsive element binding protein 3-like 4	1	152207020	AL563283	148327	1q21.3	Hs.372924	6	transcription factor activity nucleus endoplasmic reticulum Golgi apparatus regulation of transcription, DNA-dependent response to unfolded protein membrane integral to membrane sequence-specific DNA binding protein dimerization activity	Melanogenesis Huntington's disease Prostate cancer
202364_at	-0.545	8.747	-2.171	4.612e-02	0.547	-3.973	MXI1	MAX interactor 1	10	111957352, 111959978, 111975751	NM_005962	4601	10q24-q25	Hs.602078 Hs.719185	37	DNA binding transcription corepressor activity nucleus negative regulation of cell proliferation transcription regulator activity cytoplasmic sequestering of transcription factor regulation of transcription
1555118_at	0.166	2.655	2.170	4.622e-02	0.548	-3.975	ENTPD3	ectonucleoside triphosphate diphosphohydrolase 3	3	40403676	BC029869	956	3p21.3	Hs.441145	9	nucleotide binding magnesium ion binding calcium ion binding ATP binding plasma membrane nucleoside diphosphate catabolic process nucleoside triphosphate catabolic process integral to membrane hydrolase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity	Purine metabolism Pyrimidine metabolism
227017_at	0.263	5.292	2.170	4.622e-02	0.548	-3.975	ERICH1	glutamate-rich 1	8	-604199	BE644894	157697	8p23.3	Hs.655310	4
203922_s_at	-0.189	3.906	-2.170	4.623e-02	0.548	-3.975	CYBB	cytochrome b-245, beta polypeptide	X	37524213	AI308863	1536	Xp21.1	Hs.292356	96	voltage-gated ion channel activity protein binding cytoplasm mitochondrion plasma membrane ion transport inflammatory response electron carrier activity superoxide-generating NADPH oxidase activity superoxide-generating NADPH oxidase activity oxidoreductase activity heme binding electron transport chain superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex innate immune response innate immune response respiratory burst respiratory burst metal ion binding protein heterodimerization activity FAD binding	Leukocyte transendothelial migration
217724_at	-0.207	11.090	-2.170	4.624e-02	0.548	-3.975	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	AF131807	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
233937_at	0.273	2.913	2.170	4.626e-02	0.548	-3.976	GGNBP2	gametogenetin binding protein 2	17	31974916	AK024883	79893	17q12	Hs.514116	4	multicellular organismal development spermatogenesis cell differentiation cytoplasmic vesicle
AFFX-HSAC07/X00351_M_at	-0.306	10.261	-2.170	4.626e-02	0.548	-3.976	ACTB	actin, beta	7	-5533304	AFFX-HSAC07/X00351_M	60	7p15-p12	Hs.520640 Hs.708120	206	nucleotide binding structural constituent of cytoskeleton protein binding ATP binding soluble fraction cytoplasm cytosol cell motion cortical cytoskeleton NuA4 histone acetyltransferase complex nitric-oxide synthase binding MLL5-L complex	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1560277_a_at	0.171	5.159	2.170	4.628e-02	0.548	-3.976	LOC283403	hypothetical protein LOC283403	12		BC038743	283403	12q13.13	Hs.667179	1
234676_s_at	-0.181	3.348	-2.169	4.629e-02	0.548	-3.976	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)	21	-29166383	AK021678	29104	21q21.3	Hs.163846	6	nucleic acid binding protein binding protein methyltransferase activity transferase activity positive regulation of cell growth methylation protein complex
229394_s_at	-0.338	8.971	-2.169	4.629e-02	0.548	-3.976	GRLF1	glucocorticoid receptor DNA binding factor 1	19	52113772	AI275597	2909	19q13.3	Hs.509447	26	DNA binding transcription corepressor activity GTPase activator activity intracellular nucleus cytoplasm signal transduction negative regulation of transcription	Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
218379_at	-0.268	7.350	-2.169	4.632e-02	0.548	-3.977	RBM7	RNA binding motif protein 7	11	113776593	NM_016090	10179	11q23.1-q23.2	Hs.7527	10	nucleotide binding RNA binding protein binding meiosis
228992_at	-0.390	7.023	-2.169	4.632e-02	0.548	-3.977	MED28	mediator complex subunit 28	4	17225370	BF064162	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
231669_at	-0.309	5.206	-2.169	4.632e-02	0.548	-3.977	SEPP1	selenoprotein P, plasma, 1	5	-42835738	AV653290	6414	5q31	Hs.275775 Hs.718521	34	selenium metabolic process extracellular region extracellular space response to oxidative stress brain development locomotory behavior selenium binding post-embryonic development sexual reproduction growth
204989_s_at	-0.216	5.096	-2.169	4.635e-02	0.548	-3.977	ITGB4	integrin, beta 4	17	71229110, 71232370	BF305661	3691	17q25	Hs.632226	120	receptor activity protein binding cell communication cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
230132_at	0.178	5.429	2.169	4.636e-02	0.548	-3.978	ATP5SL	ATP5S-like	19	-46629063	AA147817	55101	19q13.2	Hs.351099	2
212038_s_at	-0.355	11.646	-2.169	4.637e-02	0.548	-3.978	VDAC1	voltage-dependent anion channel 1	5	-133335505	AL515918	7416	5q31	Hs.519320 Hs.709372	73	behavioral fear response protein binding mitochondrion mitochondrial outer membrane mitochondrial inner membrane plasma membrane anion transport apoptosis nerve-nerve synaptic transmission learning voltage-gated anion channel activity voltage-gated anion channel activity mitochondrial nucleoid interspecies interaction between organisms pore complex	Calcium signaling pathway Parkinson's disease Huntington's disease
217908_s_at	-0.283	11.028	-2.168	4.638e-02	0.548	-3.978	DCAF6	DDB1 and CUL4 associated factor 6	1	166172531	NM_018442	55827	1q24.2	Hs.435741	10	nucleus ligand-dependent nuclear receptor transcription coactivator activity
217761_at	0.458	9.268	2.168	4.640e-02	0.548	-3.978	ADI1	acireductone dioxygenase 1	2	-3480696	NM_018269	55256	2p25.3	Hs.502773	13	protein binding nucleus cytoplasm plasma membrane cellular amino acid biosynthetic process methionine biosynthetic process nickel ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen methionine salvage metal ion binding oxidation reduction	Cysteine and methionine metabolism Metabolic pathways
1557822_at	-0.186	1.878	-2.168	4.642e-02	0.548	-3.979	LOC401134	hypothetical gene supported by BC040544	4		BC040544	401134	4q13.1	Hs.165899	1
1569408_at	-0.213	2.758	-2.168	4.642e-02	0.548	-3.979	EIF2C4	eukaryotic translation initiation factor 2C, 4	1	36046414	BC016012	192670	1p34.3	Hs.471492	8	cytoplasmic mRNA processing body RNA binding protein binding cytoplasm mRNA catabolic process regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation
212910_at	-0.323	7.578	-2.168	4.643e-02	0.548	-3.979	THAP11	THAP domain containing 11	16	66433713	W19873	57215	16q22.1	Hs.632200	7	DNA binding nucleus cytoplasm zinc ion binding identical protein binding regulation of transcription metal ion binding
214468_at	0.821	8.940	2.168	4.643e-02	0.548	-3.979	MYH6	myosin, heavy chain 6, cardiac muscle, alpha	14	-22921038	D00943	4624	14q12	Hs.278432	23	microfilament motor activity nucleotide binding in utero embryonic development regulation of the force of heart contraction regulation of heart rate actin binding calmodulin binding ATP binding nucleus nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction adult heart development visceral muscle development regulation of blood pressure structural constituent of muscle myosin complex ATPase activity actin filament-based movement muscle filament sliding actin-dependent ATPase activity regulation of ATPase activity sarcomere organization cardiac muscle fiber development atrial cardiac muscle morphogenesis ventricular cardiac muscle morphogenesis	Cardiac muscle contraction Tight junction Hypertrophic cardiomyopathy (HCM)
239002_at	-0.177	3.569	-2.168	4.645e-02	0.548	-3.979	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	1	-195319879	AA748494	259266	1q31	Hs.121028	35	calmodulin binding nucleus cytoplasm cell cycle mitosis cell division
1563090_at	0.214	6.567	2.167	4.650e-02	0.548	-3.980	CCDC33	coiled-coil domain containing 33	15	72315719, 72397952	BC009178	80125	15q24.1	Hs.383206 Hs.621342	7	protein binding
1553560_at	0.183	3.436	2.167	4.653e-02	0.548	-3.981	VN1R4	vomeronasal 1 receptor 4	19	-58461824	NM_173857	317703	19q13.42	Hs.553685	5	receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane pheromone receptor activity response to pheromone
218718_at	0.430	7.030	2.166	4.655e-02	0.548	-3.981	PDGFC	platelet derived growth factor C	4	-157902213	NM_016205	56034	4q32	Hs.570855	22	platelet-derived growth factor receptor binding extracellular region extracellular space nucleus cytoplasm activation of transmembrane receptor protein tyrosine kinase activity central nervous system development growth factor activity organ morphogenesis membrane protein homodimerization activity cell surface binding positive regulation of DNA replication platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation regulation of peptidyl-tyrosine phosphorylation	Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Prostate cancer Melanoma
228051_at	0.275	5.272	2.166	4.657e-02	0.548	-3.982	LOC202451	hypothetical protein LOC202451	6		AI979261	202451	6q23.3	Hs.194408	1
218756_s_at	0.401	6.561	2.166	4.657e-02	0.548	-3.982	DHRS11	dehydrogenase/reductase (SDR family) member 11	17	32022338	NM_024308	79154	17q12	Hs.462859	5	binding extracellular region oxidoreductase activity oxidation reduction
232842_at	-0.208	3.868	-2.166	4.657e-02	0.548	-3.982	DOCK8	dedicator of cytokinesis 8	9	204864	AL161725	81704	9p24.3	Hs.132599	11	guanyl-nucleotide exchange factor activity GTP binding GTPase binding
218124_at	0.363	7.112	2.166	4.658e-02	0.548	-3.982	RETSAT	retinol saturase (all-trans-retinol 13,14-reductase)	2	-85422589	NM_017750	54884	2p11.2	Hs.440401	11	nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane electron carrier activity membrane oxidoreductase activity retinol metabolic process all-trans-retinol 13,14-reductase activity oxidation reduction	Retinol metabolism
225004_at	-0.228	6.971	-2.166	4.659e-02	0.548	-3.982	TMEM101	transmembrane protein 101	17	-39444081	AL525613	84336	17q21.31	Hs.514211	3	signal transducer activity cellular_component membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
205425_at	0.357	3.378	2.166	4.659e-02	0.548	-3.982	HIP1	huntingtin interacting protein 1	7	-75001344	NM_005338	3092	7q11.23	Hs.329266 Hs.619089	31	actin binding structural constituent of cytoskeleton membrane fraction nucleus cytoplasm Golgi apparatus cytoskeleton endocytosis induction of apoptosis activation of caspase activity cell death membrane cell differentiation clathrin binding clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding regulation of apoptosis regulation of transcription positive regulation of receptor-mediated endocytosis clathrin coat assembly	Huntington's disease
225864_at	0.404	5.364	2.166	4.659e-02	0.548	-3.982	FAM84B	family with sequence similarity 84, member B	8	-127633868	AL039862	157638	8q24.21	Hs.124951	5	protein binding cytoplasm plasma membrane
204744_s_at	0.375	9.932	2.166	4.663e-02	0.548	-3.983	IARS	isoleucyl-tRNA synthetase	9	-94012445, -94012445	NM_013417	3376	9q21	Hs.445403	13	nucleotide binding isoleucine-tRNA ligase activity ATP binding soluble fraction cytoplasm isoleucyl-tRNA aminoacylation zinc ion binding ligase activity	Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis
238125_at	0.249	4.682	2.166	4.663e-02	0.548	-3.983	ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif, 16	5	5193442	AI740544	170690	5p15	Hs.661915	4	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
229256_at	-0.562	7.385	-2.165	4.664e-02	0.548	-3.983	PGM2L1	phosphoglucomutase 2-like 1	11	-73719008	AV724329	283209	11q13.4	Hs.26612	6	carbohydrate metabolic process glucose metabolic process transferase activity isomerase activity intramolecular transferase activity, phosphotransferases glucose-1,6-bisphosphate synthase activity	Starch and sucrose metabolism
240365_at	-0.176	2.922	-2.165	4.672e-02	0.549	-3.984	LOC647946	hypothetical protein LOC647946	18	-35040885	AI799052	647946	18q12.2-q12.3	Hs.649350	4
226084_at	0.354	5.443	2.164	4.673e-02	0.549	-3.984	MAP1B	microtubule-associated protein 1B	5	71438873	AA554833	4131	5q13	Hs.335079	34	microtubule bundle formation actin binding structural molecule activity protein binding cytosol microtubule microtubule associated complex negative regulation of microtubule depolymerization dendrite development
232611_at	-0.221	4.137	-2.164	4.675e-02	0.549	-3.985	GOLGA2L1	golgi autoantigen, golgin subfamily a, 2-like 1	12	-99081164, -99074323	AL137680	55592	12q23.1	Hs.524660 Hs.645240	3
224333_s_at	0.272	8.570	2.164	4.680e-02	0.549	-3.986	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	AB049940	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
215440_s_at	0.622	4.638	2.164	4.681e-02	0.549	-3.986	BEX4	brain expressed, X-linked 4	X	102356675, 102356675	AL523320	56271	Xq22.1-q22.3	Hs.184736	4	nucleus cytoplasm
225509_at	-0.314	7.304	-2.163	4.685e-02	0.550	-3.987	SAP30L	SAP30-like	5	153805709	AI862477	79685	5q33.2	Hs.592566	8	nucleus nucleolus regulation of transcription
1562219_at	0.217	5.168	2.163	4.687e-02	0.550	-3.987	FLJ41649	hypothetical LOC401260	6		BC040854	401260	6p21.2	Hs.654837	1
220637_at	0.219	3.950	2.162	4.692e-02	0.550	-3.988	FAM124B	family with sequence similarity 124B	2	-224951658	NM_024785	79843	2q36.2	Hs.147585	3	protein binding
206326_at	-0.202	3.189	-2.162	4.698e-02	0.551	-3.989	GRP	gastrin-releasing peptide	18	55038379	NM_002091	2922	18q21.1-q21.32	Hs.153444	37	receptor binding neuropeptide hormone activity extracellular region extracellular space signal transduction neuropeptide signaling pathway
221493_at	-0.288	10.576	-2.162	4.699e-02	0.551	-3.989	TSPYL1	TSPY-like 1	6	-116704438	AL136629	7259	6q22-q23	Hs.458358 Hs.486292	11	molecular_function cellular_component intracellular nucleus nucleolus nucleosome assembly biological_process
1553069_at	0.190	3.374	2.162	4.699e-02	0.551	-3.989	C21orf87	chromosome 21 open reading frame 87	21		NM_153455	257357	21q22.2	Hs.190548	2
1552637_at	0.252	2.990	2.161	4.704e-02	0.551	-3.990	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	NM_080601	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
201516_at	0.289	8.265	2.161	4.706e-02	0.551	-3.991	SRM	spermidine synthase	1	-11037235	NM_003132	6723	1p36-p22	Hs.76244	12	spermidine synthase activity spermidine biosynthetic process transferase activity	Cysteine and methionine metabolism Arginine and proline metabolism beta-Alanine metabolism Glutathione metabolism Metabolic pathways
218125_s_at	-0.296	6.953	-2.160	4.710e-02	0.551	-3.991	CCDC25	coiled-coil domain containing 25	8	-27646751	NM_018246	55246	8p21.1	Hs.445512	6
205729_at	-0.227	3.109	-2.160	4.711e-02	0.551	-3.991	OSMR	oncostatin M receptor	5	38881892	NM_003999	9180	5p13.1	Hs.120658	21	positive regulation of acute inflammatory response receptor activity oncostatin-M receptor activity oncostatin-M receptor complex cell surface receptor linked signal transduction positive regulation of cell proliferation membrane integral to membrane growth factor binding response to cytokine stimulus	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
213911_s_at	-0.311	9.588	-2.160	4.712e-02	0.551	-3.992	H2AFZ	H2A histone family, member Z	4	-101088266	BF718636	3015	4q24	Hs.119192	37	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
220385_at	-0.226	5.712	-2.160	4.713e-02	0.551	-3.992	JPH2	junctophilin 2	20	-42238870, -42173750	NM_020433	57158	20q13.12	Hs.441737	11	protein binding membrane fraction microsome plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
212096_s_at	-0.224	10.073	-2.160	4.714e-02	0.551	-3.992	MTUS1	mitochondrial tumor suppressor 1	8	-17545583, -17545583, -17545583	AL096842	57509	8p22	Hs.7946	11	nucleus mitochondrion Golgi apparatus plasma membrane
1566191_at	0.197	4.870	2.160	4.715e-02	0.551	-3.992	SUZ12	suppressor of zeste 12 homolog (Drosophila)	17	27288156	AI907884	23512	17q11.2	Hs.462732	31	intracellular nucleus zinc ion binding chromatin modification ESC/E(Z) complex histone methyltransferase activity regulation of transcription metal ion binding
209323_at	-0.269	8.357	-2.160	4.715e-02	0.551	-3.992	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	11	-75738651	AF081567	5612	11q13.5	Hs.503315	12	DNA binding nucleus nucleolus response to stress signal transduction zinc ion binding negative regulation of cell proliferation metal ion binding protein dimerization activity
212468_at	-0.368	6.974	-2.160	4.717e-02	0.551	-3.992	SPAG9	sperm associated antigen 9	17	-46394534	AK023512	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
217827_s_at	-0.469	8.679	-2.159	4.718e-02	0.551	-3.993	SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	15	-63042415, -63042415	NM_016630	51324	15q21-q22	Hs.242458	10	cytoplasm endosome Golgi apparatus cytosol cytosol cell death membrane trans-Golgi network transport vesicle trans-Golgi network transport vesicle CD4 receptor binding CD4 receptor binding antigen receptor-mediated signaling pathway
212610_at	-0.302	10.103	-2.159	4.719e-02	0.551	-3.993	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	U79291	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
226026_at	-0.391	7.505	-2.159	4.719e-02	0.551	-3.993	DIRC2	disrupted in renal carcinoma 2	3	123996590	AI147467	84925	3q21.1	Hs.477346	7	transport membrane integral to membrane
223484_at	-0.179	2.940	-2.159	4.722e-02	0.552	-3.994	C15orf48	chromosome 15 open reading frame 48	15	43510054	AF228422	84419	15q21.1	Hs.112242	5	nucleus
209961_s_at	0.216	4.969	2.158	4.729e-02	0.552	-3.995	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	7	-81218151, -81209942, -81169379	M60718	3082	7q21.1	Hs.396530	327	activation of MAPK activity cell morphogenesis epithelial to mesenchymal transition liver development catalytic activity serine-type endopeptidase activity protein binding extracellular region proteolysis anti-apoptosis mitosis growth factor activity platelet alpha granule lumen hepatocyte growth factor receptor signaling pathway myoblast proliferation regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Cytokine-cytokine receptor interaction Focal adhesion Pathways in cancer Renal cell carcinoma Melanoma
208643_s_at	-0.244	8.176	-2.158	4.731e-02	0.552	-3.995	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	2	216682264	J04977	7520	2q35	Hs.388739	148	nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding promoter binding hydrolase activity provirus integration initiation of viral infection	Non-homologous end-joining
229289_at	0.336	5.567	2.158	4.731e-02	0.552	-3.995	FAM71E1	family with sequence similarity 71, member E1	19	-55661856	AL517395	112703	19q13.33	Hs.448941	1
217886_at	-0.383	7.908	-2.158	4.734e-02	0.552	-3.996	EPS15	epidermal growth factor receptor pathway substrate 15	1	-51592523, -51592522	BF213575	2060	1p32	Hs.83722	63	calcium ion binding protein binding cytoplasm endosome cytosol plasma membrane coated pit epidermal growth factor receptor signaling pathway cell proliferation protein transport vesicle organization SH3 domain binding	Endocytosis
220559_at	0.430	5.463	2.157	4.736e-02	0.552	-3.996	EN1	engrailed homeobox 1	2	-119316216	NM_001426	2019	2q13-q21	Hs.271977	20	skeletal system development transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anatomical structure morphogenesis dorsal/ventral pattern formation proximal/distal pattern formation midbrain development hindbrain development midbrain-hindbrain boundary development embryonic forelimb morphogenesis pigmentation sequence-specific DNA binding neuron development
231704_at	-0.237	4.334	-2.157	4.737e-02	0.552	-3.996	CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	7	-99192539	AV650252	1576	7q21.1	Hs.654391	362	steroid binding cytoplasm endoplasmic reticulum microsome lipid metabolic process steroid metabolic process electron carrier activity cell surface membrane integral to membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen drug metabolic process oxygen binding heme binding vitamin D3 25-hydroxylase activity taurochenodeoxycholate 6alpha-hydroxylase activity vitamin D metabolic process metal ion binding albendazole monooxygenase activity quinine 3-monooxygenase activity testosterone 6-beta-hydroxylase activity oxidation reduction	gamma-Hexachlorocyclohexane degradation Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
225212_at	-0.797	7.631	-2.157	4.737e-02	0.552	-3.996	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	9	129870299, 129893948, 129900637, 129900656	BC005163	114789	9q34.11	Hs.5476	6	binding calcium ion binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
202278_s_at	-0.160	5.620	-2.157	4.738e-02	0.552	-3.996	SPTLC1	serine palmitoyltransferase, long chain base subunit 1	9	-93881166, -93833247	NM_006415	10558	9q22.2	Hs.90458	22	serine C-palmitoyltransferase activity protein binding endoplasmic reticulum acyltransferase activity biosynthetic process membrane integral to membrane transferase activity, transferring nitrogenous groups serine C-palmitoyltransferase complex sphingolipid biosynthetic process pyridoxal phosphate binding	Sphingolipid metabolism Metabolic pathways
231006_at	-0.217	5.769	-2.157	4.739e-02	0.552	-3.996	SPATA8	spermatogenesis associated 8	15	95127682	AI638541	145946	15q26.2	Hs.326528	3
1555787_at	0.183	4.156	2.157	4.741e-02	0.552	-3.997	C11orf63	chromosome 11 open reading frame 63	11	122258682, 122258682	BC009820	79864	11q24.1	Hs.164705	3
204070_at	0.482	5.955	2.157	4.742e-02	0.552	-3.997	RARRES3	retinoic acid receptor responder (tazarotene induced) 3	11	63060848	NM_004585	5920	11q23	Hs.17466	37	negative regulation of cell proliferation
218573_at	0.220	7.227	2.157	4.743e-02	0.552	-3.997	MAGEH1	melanoma antigen family H, 1	X	55495262	NM_014061	28986	Xp11.21	Hs.279819	11	apoptosis
215911_x_at	-0.238	3.056	-2.157	4.744e-02	0.552	-3.997	ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	X	152454773	AW615612	492	Xq28	Hs.533956 Hs.658008	15	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding Golgi apparatus plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
221723_s_at	0.210	4.332	2.156	4.747e-02	0.552	-3.998	SLC4A5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	2	-74302068, -74296876	AF243499	57835	2p13	Hs.594099	10	transporter activity inorganic anion exchanger activity plasma membrane sodium ion transport anion transport anion transmembrane transporter activity integral to membrane sodium ion binding
210115_at	0.313	4.086	2.155	4.755e-02	0.553	-3.999	RPL39L	ribosomal protein L39-like	3	-188321434	L05096	116832	3q27	Hs.647900	4	structural constituent of ribosome intracellular ribosome translation spermatogenesis cytosolic large ribosomal subunit
222058_at	0.163	4.403	2.155	4.756e-02	0.553	-4.000	RNF130	ring finger protein 130	5	-179315079	AW194818	55819	5q35.3	Hs.484363	7	molecular_function protein binding apoptosis zinc ion binding membrane integral to membrane metal ion binding
224711_at	-0.264	7.839	-2.155	4.756e-02	0.553	-4.000	YY1	YY1 transcription factor	14	99774854	AI670903	7528	14q	Hs.388927	97	transcription factor activity transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus transcription factor complex plasma membrane regulation of transcription from RNA polymerase II promoter zinc ion binding anterior/posterior pattern formation nuclear matrix PcG protein complex metal ion binding camera-type eye morphogenesis
213901_x_at	-0.353	7.998	-2.155	4.756e-02	0.553	-4.000	RBM9	RNA binding motif protein 9	22	-34464728, -34464728	AW149379	23543	22q13.1	Hs.282998	18	nucleotide binding transcription corepressor activity RNA binding nucleus cytoplasm mRNA processing transcription factor binding RNA splicing RNA metabolic process negative regulation of transcription estrogen receptor signaling pathway regulation of cell proliferation
211799_x_at	0.277	8.293	2.155	4.760e-02	0.553	-4.000	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	U62824	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
224622_at	-0.240	7.355	-2.155	4.761e-02	0.553	-4.000	TBC1D14	TBC1 domain family, member 14	4	6962071, 6962395, 7039789	AB037743	57533	4p16.1	Hs.518611	7	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
210638_s_at	-0.186	8.833	-2.155	4.761e-02	0.553	-4.000	FBXO9	F-box protein 9	6	53037754, 53038215, 53043729	AF176704	26268	6p12.3-p11.2	Hs.216653	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein ubiquitination modification-dependent protein catabolic process
229376_at	0.482	5.757	2.154	4.770e-02	0.553	-4.002	PROX1	prospero homeobox 1	1	212228482	BF223556	5629	1q32.2-q32.3	Hs.585369	34	cell fate determination kidney development liver development lymph vessel development DNA binding RNA polymerase II transcription factor activity, enhancer binding nucleus cytoplasm multicellular organismal development brain development negative regulation of cell proliferation dorsal spinal cord development neural tube development muscle thin filament assembly lung development transcription regulator activity olfactory placode formation pancreas development otic placode formation endothelial cell differentiation regulation of transcription positive regulation of cell cycle optic placode formation involved in camera-type eye venous blood vessel morphogenesis ventricular cardiac myofibril development atrial cardiac muscle morphogenesis ventricular cardiac muscle morphogenesis retina morphogenesis in camera-type eye endocardium formation positive regulation of sarcomere organization ventricular septum morphogenesis aorta smooth muscle tissue morphogenesis positive regulation of heart growth lens fiber cell morphogenesis
212257_s_at	-0.274	4.450	-2.154	4.771e-02	0.553	-4.002	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	AW131754	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
210695_s_at	0.237	6.820	2.153	4.773e-02	0.553	-4.003	WWOX	WW domain containing oxidoreductase	16	76691051, 76691051, 76691051	U13395	51741	16q23.3-q24.1	Hs.461453	64	nucleus cytoplasm mitochondrion Golgi apparatus steroid metabolic process oxidoreductase activity oxidoreductase activity protein dimerization activity coenzyme binding oxidation reduction
213538_at	-0.248	6.848	-2.153	4.774e-02	0.553	-4.003	SON	SON DNA binding protein	21	33837219, 33837219	AI936458	6651	21q22.1-q22.2 21q22.11	Hs.517262	28	DNA binding double-stranded RNA binding protein binding cellular_component intracellular nucleus anti-apoptosis nuclear speck
1552338_at	0.266	3.678	2.153	4.779e-02	0.554	-4.004	GSC	goosecoid homeobox	14	-94304312	AY177407	145258	14q32.1	Hs.440438	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus transcription factor complex regulation of transcription, DNA-dependent multicellular organismal development gastrulation anatomical structure morphogenesis dorsal/ventral neural tube patterning negative regulation of Wnt receptor signaling pathway forebrain development sequence-specific DNA binding ear development muscle organ morphogenesis embryonic skeletal system morphogenesis
212274_at	-0.383	9.759	-2.153	4.779e-02	0.554	-4.004	LPIN1	lipin 1	2	11804190	AV705559	23175	2p25.1	Hs.467740	28	molecular_function nucleus lipid metabolic process phosphatidate phosphatase activity ruffle organization actin cytoskeleton reorganization cellular response to insulin stimulus regulation of fat cell differentiation
213231_at	0.169	4.142	2.153	4.779e-02	0.554	-4.004	DMWD	dystrophia myotonica, WD repeat containing	19	-50978103	L19267	1762	19q13.3	Hs.515474	13	molecular_function cellular_component meiosis
213201_s_at	0.255	13.412	2.152	4.781e-02	0.554	-4.004	TNNT1	troponin T type 1 (skeletal, slow)	19	-60335972	AJ011712	7138	19q13.4	Hs.631558	29	skeletal muscle contraction protein binding tropomyosin binding troponin complex troponin complex negative regulation of muscle contraction
231603_at	0.179	2.786	2.152	4.783e-02	0.554	-4.004	RNASE11	ribonuclease, RNase A family, 11 (non-active)	14	-20120891	AW188146	122651	14q11.2	Hs.112761	5	nucleic acid binding endonuclease activity pancreatic ribonuclease activity extracellular region hydrolase activity
224326_s_at	-0.335	6.486	-2.152	4.783e-02	0.554	-4.004	PCGF6	polycomb group ring finger 6	10	-105052542	AB047006	84108	10q24.33	Hs.719328	12	transcription factor activity protein binding nucleus zinc ion binding negative regulation of transcription PcG protein complex metal ion binding
213314_at	-0.347	4.857	-2.152	4.786e-02	0.554	-4.005	C6orf162	chromosome 6 open reading frame 162	6	88089024	NM_020425	57150	6q15-q16.1	Hs.70769	4	membrane integral to membrane
205167_s_at	0.234	3.429	2.152	4.788e-02	0.554	-4.005	CDC25C	cell division cycle 25 homolog C (S. pombe)	5	-137648857	NM_001790	995	5q31	Hs.656	108	regulation of cyclin-dependent protein kinase activity protein tyrosine phosphatase activity protein binding cellular_component intracellular nucleus nucleoplasm cytoplasm cytosol DNA replication protein amino acid dephosphorylation cell cycle regulation of mitosis traversing start control point of mitotic cell cycle cell proliferation hydrolase activity interspecies interaction between organisms WW domain binding cell division	Cell cycle
65585_at	0.313	4.208	2.152	4.790e-02	0.554	-4.006	FAM86B1	family with sequence similarity 86, member B1	8	-12077021	AA527515	85002	8p23.1	Hs.458413 Hs.567527	3
231770_x_at	0.201	6.146	2.151	4.790e-02	0.554	-4.006	C2orf86	chromosome 2 open reading frame 86	2	-63202038, -63202038	AK022647	51057	2p15	Hs.414952	6
206202_at	0.163	2.233	2.151	4.793e-02	0.554	-4.006	MEOX2	mesenchyme homeobox 2	7	-15617361	NM_005924	4223	7p22.1-p21.3	Hs.170355	19	angiogenesis somite specification transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent multicellular organismal development skeletal muscle tissue development blood circulation sequence-specific DNA binding palate development limb development
215111_s_at	-0.243	10.524	-2.151	4.793e-02	0.554	-4.006	TSC22D1	TSC22 domain family, member 1	13	-43905658, -43905654	AK027071	8848	13q14	Hs.507916	23	transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter
222626_at	-0.249	4.971	-2.151	4.794e-02	0.554	-4.006	RBM26	RNA binding motif protein 26	13	-78792099	T79937	64062	13q31.1	Hs.558528	8	nucleotide binding RNA binding zinc ion binding metal ion binding
218794_s_at	-0.216	5.401	-2.151	4.795e-02	0.554	-4.007	TXNL4B	thioredoxin-like 4B	16	-70676258, -70676258, -70676258	NM_017853	54957	16q22.2	Hs.134406	12	nucleus spliceosomal complex mRNA processing cell cycle mitosis RNA splicing
230264_s_at	-0.329	9.723	-2.150	4.801e-02	0.554	-4.008	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	X	-15753849	AA551090	8905	Xp22.2	Hs.653504 Hs.656471	21	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
217150_s_at	0.269	5.123	2.150	4.802e-02	0.554	-4.008	NF2	neurofibromin 2 (merlin)	22	28329544, 28329544	S73854	4771	22q12.2	Hs.187898	131	mesoderm formation ruffle negative regulation of cell-matrix adhesion nucleus nucleolus cytoplasm early endosome cytoskeleton plasma membrane adherens junction negative regulation of protein kinase activity ectoderm development cytoskeletal protein binding negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell proliferation Schwann cell proliferation extrinsic to membrane negative regulation of cell-cell adhesion lamellipodium actin cytoskeleton organization filopodium negative regulation of cell migration cleavage furrow odontogenesis of dentine-containing tooth negative regulation of tyrosine phosphorylation of Stat3 protein negative regulation of tyrosine phosphorylation of Stat5 protein negative regulation of MAPKKK cascade cell-cell junction organization negative regulation of JAK-STAT cascade perinuclear region of cytoplasm positive regulation of stress fiber formation
241937_s_at	0.395	4.444	2.150	4.802e-02	0.554	-4.008	WDR4	WD repeat domain 4	21	-43142404, -43136272	AA577678	10785	21q22.3	Hs.248815	10	protein binding nucleus nucleoplasm cytoplasm tRNA modification tRNA (guanine-N7-)-methyltransferase activity
229043_at	-0.391	6.264	-2.150	4.805e-02	0.554	-4.008	PAPD5	PAP associated domain containing 5	16	48745568	AI492902	64282	16q12.1	Hs.514342	5	molecular_function DNA binding DNA-directed DNA polymerase activity cellular_component nucleus DNA replication cell cycle mitosis biological_process transferase activity nucleotidyltransferase activity cell division
209742_s_at	0.170	13.751	2.149	4.811e-02	0.555	-4.009	MYL2	myosin, light chain 2, regulatory, cardiac, slow	12	-109833006	AF020768	4633	12q24.11	Hs.75535	34	motor activity actin monomer binding calcium ion binding protein binding regulation of striated muscle contraction structural constituent of muscle myosin complex sarcomere negative regulation of cell growth myosin heavy chain binding cardiac myofibril assembly ventricular cardiac muscle morphogenesis heart contraction	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM)
210374_x_at	0.162	4.647	2.149	4.813e-02	0.555	-4.010	PTGER3	prostaglandin E receptor 3 (subtype EP3)	1	-71244124, -71209051, -71190702, -71090623	D38300	5733	1p31.2	Hs.445000	45	ligand-dependent nuclear receptor activity G-protein coupled receptor activity prostaglandin E receptor activity nuclear envelope plasma membrane integral to plasma membrane transcription, DNA-dependent signal transduction G-protein coupled receptor protein signaling pathway cell death	Calcium signaling pathway Neuroactive ligand-receptor interaction
225069_at	-0.306	8.085	-2.149	4.814e-02	0.555	-4.010	PCYT1A	phosphate cytidylyltransferase 1, choline, alpha	3	-197449649	BF063382	5130	3q29	Hs.435767	15	choline-phosphate cytidylyltransferase activity soluble fraction cytoplasm endoplasmic reticulum membrane cytosol phosphatidylcholine biosynthetic process phospholipid biosynthetic process biosynthetic process response to abiotic stimulus membrane transferase activity nucleotidyltransferase activity glycogen granule	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
207574_s_at	-0.653	6.360	-2.148	4.819e-02	0.555	-4.011	GADD45B	growth arrest and DNA-damage-inducible, beta	19	2427134	NM_015675	4616	19p13.3	Hs.110571	33	activation of MAPKKK activity activation of MAPKK activity protein binding negative regulation of protein kinase activity apoptosis response to stress multicellular organismal development cell differentiation regulation of cell cycle	MAPK signaling pathway Cell cycle p53 signaling pathway
218108_at	-0.234	6.381	-2.148	4.819e-02	0.555	-4.011	UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	14	92743153	NM_018108	55148	14q32.12	Hs.648806	7	molecular_function ubiquitin-protein ligase activity protein binding biological_process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
228302_x_at	0.180	3.618	2.148	4.822e-02	0.555	-4.011	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	1	-20681470	AW162846	55450	1p36.12	Hs.197922	4	plasma membrane calcium-dependent protein kinase inhibitor activity postsynaptic density synaptosome protein kinase binding cell junction dendrite cell soma synapse postsynaptic membrane
210458_s_at	-0.526	4.705	-2.148	4.822e-02	0.555	-4.011	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	BC003388	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
229861_at	0.292	5.353	2.148	4.825e-02	0.555	-4.012	RFFL	ring finger and FYVE-like domain containing 1	17	-30360243, -30360243	N66669	117584	17q12	Hs.13680	11	protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding
226035_at	0.448	6.610	2.148	4.826e-02	0.555	-4.012	USP31	ubiquitin specific peptidase 31	16	-22980228	AA102581	57478	16p12.2	Hs.183817	8	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
240164_at	0.279	3.980	2.147	4.827e-02	0.555	-4.012	MUC4	mucin 4, cell surface associated	3	-196959308	AW388645	4585	3q29	Hs.369646	71	ErbB-2 class receptor binding protein binding extracellular region proteinaceous extracellular matrix integral to plasma membrane cell adhesion cell-matrix adhesion biological_process membrane extracellular matrix constituent, lubricant activity
220350_at	0.257	4.720	2.147	4.828e-02	0.555	-4.012	ZNF235	zinc finger protein 235	19	-49482340	NM_004234	9310	19q13.2	Hs.298089 Hs.613424	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214925_s_at	-0.276	4.899	-2.147	4.830e-02	0.555	-4.013	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	9	130354686	AK026484	6709	9q33-q34	Hs.372331	70	actin binding structural constituent of cytoskeleton calcium ion binding calmodulin binding membrane fraction cytoplasm cytosol cytoskeleton cell cortex spectrin actin filament capping	Tight junction
221413_at	0.193	4.764	2.147	4.831e-02	0.555	-4.013	KCNAB3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	17	-7766751	NM_004732	9196	17p13.1	Hs.435074	6	voltage-gated ion channel activity voltage-gated potassium channel activity cytoplasm ion transport potassium ion transport potassium channel regulator activity integral to membrane oxidoreductase activity potassium ion binding oxidation reduction
213656_s_at	-0.273	9.144	-2.147	4.832e-02	0.555	-4.013	KLC1	kinesin light chain 1	14	103165277, 103165277	BF593594	3831	14q32.3	Hs.20107 Hs.657678	31	microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle
207458_at	0.176	5.401	2.147	4.832e-02	0.555	-4.013	C8orf51	chromosome 8 open reading frame 51	8	-144520168	NM_024035	78998	8q24	Hs.245886 Hs.618477	4
204920_at	0.293	5.192	2.147	4.833e-02	0.555	-4.013	CPS1	carbamoyl-phosphate synthetase 1, mitochondrial	2	211050653, 211129570, 211166334	AF154830	1373	2q35	Hs.149252	23	urea cycle nucleotide binding carbamoyl-phosphate synthase (ammonia) activity protein binding ATP binding mitochondrion glycogen catabolic process glutamine metabolic process ligase activity citrulline biosynthetic process triglyceride catabolic process response to lipopolysaccharide mitochondrial nucleoid positive regulation of vasodilation nitric oxide metabolic process carbamoyl phosphate biosynthetic process	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Nitrogen metabolism Metabolic pathways
225597_at	0.235	3.841	2.147	4.833e-02	0.555	-4.013	SLC45A4	solute carrier family 45, member 4	8	-142290051	AI346128	57210	8q24.3	Hs.372492	2	transport membrane integral to membrane
213647_at	0.359	5.679	2.147	4.835e-02	0.555	-4.014	DNA2	DNA replication helicase 2 homolog (yeast)	10	-69843826	D42046	1763	10q21.3-q22.1	Hs.532446	11	nucleotide binding DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleoplasm mitochondrion gamma DNA polymerase complex mitochondrial DNA replication base-excision repair hydrolase activity ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity DNA replication, removal of RNA primer positive regulation of DNA replication	DNA replication
205237_at	0.187	3.965	2.146	4.836e-02	0.555	-4.014	FCN1	ficolin (collagen/fibrinogen domain containing) 1	9	-136941254	NM_002003	2219	9q34	Hs.440898	20	antigen binding receptor binding calcium ion binding sugar binding extracellular region signal transduction opsonization
217173_s_at	-0.179	5.893	-2.146	4.838e-02	0.555	-4.014	LDLR	low density lipoprotein receptor	19	11061056	S70123	3949	19p13.3	Hs.213289 Hs.713967	374	transmembrane receptor activity low-density lipoprotein receptor activity calcium ion binding endosome plasma membrane plasma membrane integral to plasma membrane coated pit protein amino acid O-linked glycosylation lipid metabolic process lipid transport endocytosis steroid metabolic process cholesterol metabolic process endosome membrane very-low-density lipoprotein receptor activity intestinal cholesterol absorption clathrin-coated endocytic vesicle membrane low-density lipoprotein particle low-density lipoprotein particle clearance lipoprotein catabolic process cholesterol homeostasis interspecies interaction between organisms	Endocytosis
217803_at	-0.425	7.676	-2.146	4.839e-02	0.555	-4.014	GOLPH3	golgi phosphoprotein 3 (coat-protein)	5	-32160580	NM_022130	64083	5p13.3	Hs.408909	6	protein binding cytoplasm mitochondrion Golgi apparatus trans-Golgi network membrane positive regulation of TOR signaling pathway
232183_at	-0.240	6.202	-2.146	4.843e-02	0.555	-4.015	SERAC1	serine active site containing 1	6	-158450523	AA128978	84947	6q25.3	Hs.154706	6	binding membrane integral to membrane
226338_at	-0.397	6.736	-2.145	4.845e-02	0.555	-4.015	TMEM55A	transmembrane protein 55A	8	-92075674	AA604382	55529	8q21.3	Hs.202517	4	lysosome endosome membrane integral to membrane hydrolase activity
229526_at	0.643	5.380	2.145	4.847e-02	0.555	-4.016	AQP11	aquaporin 11	11	76978327	AI886656	282679	11q14.1	Hs.503345	5	kidney development transporter activity cytoplasm endoplasmic reticulum ion transport water transport cell surface glycerol transport urea transport membrane integral to membrane endosomal lumen acidification
219862_s_at	-0.338	7.863	-2.145	4.850e-02	0.556	-4.016	NARF	nuclear prelamin A recognition factor	17	78009348, 78009828	NM_012336	26502	17q25.3	Hs.256526 Hs.600304	10	lamin binding nucleus lamin filament nuclear lumen
219717_at	-0.574	4.978	-2.145	4.850e-02	0.556	-4.016	DCAF16	DDB1 and CUL4 associated factor 16	4	-17411375	NM_017741	54876	4p15.31	Hs.614787	2
230263_s_at	-0.663	3.961	-2.144	4.854e-02	0.556	-4.017	DOCK5	dedicator of cytokinesis 5	8	25098203	BF447954	80005	8p21.2	Hs.195403	7	guanyl-nucleotide exchange factor activity cytoplasm
212069_s_at	0.249	6.337	2.144	4.856e-02	0.556	-4.017	BAT2L	HLA-B associated transcript 2-like	9	133295297	AK026025	84726	9q34.13	Hs.495349 Hs.703868	9
230674_at	-0.232	4.080	-2.144	4.859e-02	0.556	-4.018	LGR4	leucine-rich repeat-containing G protein-coupled receptor 4	11	-27344083	BE502880	55366	11p14-p13	Hs.502176	6	receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane protein-hormone receptor activity
209409_at	-0.568	8.607	-2.144	4.859e-02	0.556	-4.018	GRB10	growth factor receptor-bound protein 10	7	-50625253, -50625253, -50625253	D86962	2887	7p12-p11.2	Hs.164060	51	SH3/SH2 adaptor activity insulin receptor binding protein binding cytoplasm plasma membrane signal transduction cell-cell signaling negative regulation of glucose import negative regulation of insulin receptor signaling pathway
202417_at	-0.336	8.783	-2.144	4.860e-02	0.556	-4.018	KEAP1	kelch-like ECH-associated protein 1	19	-10457795, -10457795	NM_012289	9817	19p13.2	Hs.465870	51	in utero embryonic development protein binding nucleus nucleolus cytoplasm endoplasmic reticulum centrosome transcription regulator activity regulation of transcription regulation of epidermal cell differentiation	Ubiquitin mediated proteolysis
202981_x_at	-0.246	8.135	-2.144	4.860e-02	0.556	-4.018	SIAH1	seven in absentia homolog 1 (Drosophila)	16	-46951954, -46951946	NM_003031	6477	16q12	Hs.295923	64	ubiquitin-protein ligase activity nucleus cytoplasm proteolysis ubiquitin-dependent protein catabolic process apoptosis cell cycle multicellular organismal development spermatogenesis nervous system development axon guidance protein C-terminus binding zinc ion binding anatomical structure morphogenesis protein ubiquitination ligase activity cell differentiation metal ion binding	p53 signaling pathway Ubiquitin mediated proteolysis Wnt signaling pathway
227310_at	0.176	3.014	2.144	4.862e-02	0.556	-4.018	ADSS	adenylosuccinate synthase	1	-242638418	AI346678	159	1cen-q12	Hs.498313	11	nucleotide binding magnesium ion binding immune system process adenylosuccinate synthase activity adenylosuccinate synthase activity GTP binding cellular_component cytoplasm purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process ligase activity phosphate binding	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
212932_at	-0.227	5.754	-2.144	4.862e-02	0.556	-4.018	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	AK022494	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
204053_x_at	-0.303	6.591	-2.144	4.863e-02	0.556	-4.019	PTEN	phosphatase and tensin homolog	10	89613174	U96180	5728	10q23.3	Hs.500466	557	regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade	Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer
228346_at	0.389	6.290	2.143	4.866e-02	0.556	-4.019	ZNF844	zinc finger protein 844	19	12036545	H47630	284391	19p13.2	Hs.646391	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222907_x_at	-0.515	5.851	-2.143	4.869e-02	0.556	-4.020	TMEM50B	transmembrane protein 50B	21	-33743317	BC000569	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
224206_x_at	-0.320	6.499	-2.143	4.869e-02	0.556	-4.020	MYNN	myoneurin	3	170973546	AF155508	55892	3q26.2	Hs.507025	6	transcription factor activity protein binding intracellular nucleus transcription, DNA-dependent zinc ion binding regulation of transcription metal ion binding
222123_s_at	0.284	4.272	2.143	4.871e-02	0.556	-4.020	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	AK021881	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
226500_at	-0.171	8.750	-2.142	4.873e-02	0.556	-4.020	ZBTB47	zinc finger and BTB domain containing 47	3	42675877	AI806872	92999	3p22.1	Hs.409561	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
202085_at	-0.379	6.619	-2.142	4.874e-02	0.556	-4.020	TJP2	tight junction protein 2 (zona occludens 2)	9	70978908	NM_004817	9414	9q13-q21	Hs.50382	49	guanylate kinase activity protein binding nucleus cytoplasm plasma membrane adherens junction tight junction cell junction	Tight junction Vibrio cholerae infection
216304_x_at	-0.224	9.276	-2.142	4.874e-02	0.556	-4.021	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AJ295618	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
216801_at	0.198	4.293	2.141	4.882e-02	0.556	-4.022	CROCC	ciliary rootlet coiled-coil, rootletin	1	17121031	AK026910	9696	1pter-p36.11	Hs.309403	10	structural molecule activity protein binding centriole cell cycle protein localization kinesin binding cell projection organization ciliary rootlet centrosome organization
1557073_s_at	-0.297	5.441	-2.141	4.883e-02	0.556	-4.022	TTBK2	tau tubulin kinase 2	15	-40823835	AK074481	146057	15q15.2	Hs.659846 Hs.713940	12	nucleotide binding protein serine/threonine kinase activity ATP binding cell death transferase activity peptidyl-serine phosphorylation
231917_at	-0.341	3.955	-2.141	4.884e-02	0.556	-4.022	GFM2	G elongation factor, mitochondrial 2	5	-74068249, -74052786	AK025314	84340	5q13	Hs.277154	5	nucleotide binding translation elongation factor activity GTPase activity GTP binding mitochondrion translation
1552878_at	0.157	2.230	2.141	4.885e-02	0.556	-4.022	ATOH7	atonal homolog 7 (Drosophila)	10	-69660387	BC032621	220202	10q21.3 10q21.3-q22.1	Hs.175396	4	DNA binding nucleus multicellular organismal development nervous system development circadian rhythm entrainment of circadian clock cell differentiation transcription regulator activity regulation of transcription
219595_at	0.202	5.541	2.141	4.886e-02	0.556	-4.023	ZNF26	zinc finger protein 26	12	132073128	NM_019591	7574	12q24.33	Hs.489608	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1569699_at	0.300	4.139	2.141	4.888e-02	0.556	-4.023	AK7	adenylate kinase 7	14	95928200	BC023986	122481	14q32.2	Hs.667462	4	nucleotide binding adenylate kinase activity ATP binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process metabolic process transferase activity nucleobase, nucleoside, nucleotide kinase activity	Purine metabolism Metabolic pathways
201135_at	0.269	10.281	2.141	4.888e-02	0.556	-4.023	ECHS1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	10	-135025976	NM_004092	1892	10q26.2-q26.3	Hs.76394	16	enoyl-CoA hydratase activity enoyl-CoA hydratase activity protein binding mitochondrion mitochondrial matrix mitochondrial matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process lyase activity	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Metabolic pathways
224436_s_at	0.502	7.121	2.141	4.889e-02	0.556	-4.023	NIPSNAP3A	nipsnap homolog 3A (C. elegans)	9	106549789	BC005935	25934	9q31.1	Hs.530275	6	cytoplasm cytosol
235344_at	-0.417	6.993	-2.140	4.894e-02	0.557	-4.024	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	BG288054	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
219925_at	-0.174	3.493	-2.140	4.894e-02	0.557	-4.024	ZMYM6	zinc finger, MYM-type 6	1	-35224353	NM_007167	9204	1p34.2	Hs.533986 Hs.623978 Hs.675613	8	DNA binding nucleus nucleolus multicellular organismal development zinc ion binding metal ion binding
220018_at	-0.447	4.402	-2.140	4.899e-02	0.557	-4.025	CBLL1	Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1	7	107171514	NM_024814	79872	7q22.3-q31.1	Hs.592271	9	protein binding intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
220798_x_at	0.146	5.896	2.140	4.899e-02	0.557	-4.025	PRG2	plasticity-related gene 2	19	-763517	NM_024888	79948	19p13.3	Hs.546439	5	phosphatidate phosphatase activity membrane integral to membrane hydrolase activity
1560715_at	0.246	3.428	2.140	4.899e-02	0.557	-4.025	P4HA3	prolyl 4-hydroxylase, alpha polypeptide III	11	-73655349	AL833965	283208	11q13.4	Hs.660541	4	procollagen-proline 4-dioxygenase activity binding iron ion binding endoplasmic reticulum endoplasmic reticulum lumen oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Arginine and proline metabolism Metabolic pathways
228256_s_at	0.281	5.578	2.139	4.901e-02	0.557	-4.025	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A	5	-111526213	AU144565	64097	5q22.1-q22.2	Hs.584954	7	binding cellular_component cytoplasm cytoskeleton cytoskeletal protein binding biological_process extrinsic to membrane
224437_s_at	-0.279	8.207	-2.139	4.902e-02	0.557	-4.025	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	BC005937	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
223367_at	0.340	6.770	2.139	4.903e-02	0.557	-4.026	DNAJC30	DnaJ (Hsp40) homolog, subfamily C, member 30	7	-72733183	BC005056	84277	7q11.23	Hs.647046	6	protein folding heat shock protein binding unfolded protein binding
236313_at	0.953	5.377	2.139	4.903e-02	0.557	-4.026	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	9	-21992901	AW444761	1030	9p21	Hs.72901	158	regulation of cyclin-dependent protein kinase activity G2/M transition of mitotic cell cycle cyclin-dependent protein kinase inhibitor activity protein binding cytoplasm cell cycle cell cycle arrest protein kinase binding positive regulation of transforming growth factor beta receptor signaling pathway G1/S transition checkpoint cellular response to extracellular stimulus cellular response to nutrient negative regulation of phosphorylation negative regulation of epithelial cell proliferation	Cell cycle TGF-beta signaling pathway Pathways in cancer Small cell lung cancer
205988_at	0.198	4.907	2.139	4.908e-02	0.557	-4.026	CD84	CD84 molecule	1	-158782410	NM_003874	8832	1q24	Hs.398093	23	receptor activity protein binding plasma membrane integral to plasma membrane defense response cell adhesion homophilic cell adhesion
228153_at	-0.318	9.778	-2.139	4.908e-02	0.557	-4.027	RNF144B	ring finger protein 144B	6	18495572	AI953847	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
209200_at	-0.432	10.422	-2.138	4.912e-02	0.557	-4.027	MEF2C	myocyte enhancer factor 2C	5	-88049814, -88049814	AL536517	4208	5q14	Hs.653394	56	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development negative regulation of specific transcription from RNA polymerase II promoter nuclear speck cell differentiation sequence-specific DNA binding positive regulation of survival gene product expression	MAPK signaling pathway
231258_at	-0.243	4.199	-2.138	4.914e-02	0.557	-4.027	TMEM66	transmembrane protein 66	8	-30040172	AV648367	51669	8p12	Hs.521487	10	membrane integral to membrane
200861_at	0.181	6.723	2.138	4.914e-02	0.557	-4.028	CNOT1	CCR4-NOT transcription complex, subunit 1	16	-57134732, -57111355	NM_016284	23019	16q21	Hs.460923 Hs.716474	9	regulation of transcription	RNA degradation
221366_at	-0.255	3.685	-2.137	4.922e-02	0.557	-4.029	NKX6-1	NK6 homeobox 1	4	-85633459	NM_006168	4825	4q21.2-q22	Hs.546270	7	transcription factor activity nucleus regulation of transcription, DNA-dependent smoothened signaling pathway multicellular organismal development organ morphogenesis regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification cell differentiation endocrine pancreas development sequence-specific DNA binding intracellular part positive regulation of neuron differentiation negative regulation of glial cell differentiation positive regulation of glial cell differentiation oligodendrocyte differentiation	Maturity onset diabetes of the young
223167_s_at	-0.659	8.359	-2.137	4.923e-02	0.557	-4.029	USP25	ubiquitin specific peptidase 25	21	16024366	AF170562	29761	21q11.2	Hs.473370	11	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
209619_at	0.410	7.841	2.137	4.923e-02	0.557	-4.029	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	5	-149761394, -149761392	K01144	972	5q32	Hs.436568	58	prostaglandin biosynthetic process intracellular protein complex assembly intracellular protein transport immune response signal transduction cell proliferation membrane integral to membrane immunoglobulin mediated immune response antigen processing and presentation of endogenous antigen cytokine binding MHC class II protein binding identical protein binding regulation of macrophage activation negative regulation of apoptosis T cell selection	Antigen processing and presentation
63305_at	0.223	6.646	2.137	4.928e-02	0.558	-4.030	PKNOX2	PBX/knotted 1 homeobox 2	11	124539768	D81792	63876		Hs.719275	7	transcription factor activity actin monomer binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter actin cytoskeleton microtubule cytoskeleton sequence-specific DNA binding actin filament binding
226269_at	0.395	4.990	2.136	4.929e-02	0.558	-4.030	GDAP1	ganglioside-induced differentiation-associated protein 1	8	75425172, 75425207	BF002104	54332	8q21.11	Hs.168950	30	cytoplasm response to retinoic acid
227272_at	-0.231	7.763	-2.136	4.930e-02	0.558	-4.030	C15orf52	chromosome 15 open reading frame 52	15	-38410944	BE673226	388115	15q15.1	Hs.32433	3
217043_s_at	-0.276	6.634	-2.135	4.940e-02	0.558	-4.032	MFN1	mitofusin 1	3	180548173	U95822	55669	3q26.33	Hs.478383	16	nucleotide binding GTPase activity GTP binding cytoplasm mitochondrion mitochondrial outer membrane mitochondrial fusion biological_process membrane integral to membrane hydrolase activity
237111_at	-0.263	3.863	-2.135	4.942e-02	0.558	-4.032	FLJ44450	hypothetical gene supported by AK126414	2		AW118588	388942	2p21	Hs.631883
208998_at	0.547	9.646	2.135	4.942e-02	0.558	-4.032	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	11	-73363363	U94592	7351	11q13	Hs.80658	153	response to superoxide binding mitochondrion mitochondrial inner membrane transport mitochondrial transport proton transport membrane integral to membrane
235850_at	0.366	7.074	2.135	4.942e-02	0.558	-4.032	WDR5B	WD repeat domain 5B	3	-123613389	BF434228	54554	3q21.1	Hs.567513 Hs.594258	6	modification-dependent protein catabolic process
219836_at	0.233	4.081	2.135	4.942e-02	0.558	-4.032	ZBED2	zinc finger, BED-type containing 2	3	-112794436	NM_024508	79413	3q13.2	Hs.136912	3	DNA binding zinc ion binding metal ion binding
232604_at	0.238	5.571	2.135	4.945e-02	0.559	-4.033	ZNF541	zinc finger protein 541	19	-52715759	AL136846	84215	19q13.33	Hs.14161	3	DNA binding intracellular nucleus multicellular organismal development spermatogenesis zinc ion binding cell differentiation regulation of transcription metal ion binding
1557820_at	-0.242	10.500	-2.135	4.946e-02	0.559	-4.033	AFG3L2	AFG3 ATPase family gene 3-like 2 (yeast)	18	-12319107	AA905788	10939	18p11	Hs.528996	5	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion mitochondrial inner membrane proteolysis axonogenesis neuromuscular junction development peptidase activity zinc ion binding membrane integral to membrane death nucleoside-triphosphatase activity nerve development regulation of multicellular organism growth myelination metal ion binding muscle fiber development unfolded protein binding righting reflex
227001_at	0.354	4.408	2.134	4.948e-02	0.559	-4.033	NIPAL2	NIPA-like domain containing 2	8	-99273562	AI096706	79815	8q22.2	Hs.309489	3	membrane integral to membrane
222779_s_at	0.181	5.682	2.134	4.952e-02	0.559	-4.034	C17orf85	chromosome 17 open reading frame 85	17	-3661208	AA706815	55421	17p13.2	Hs.120963	6
221645_s_at	0.399	4.360	2.134	4.955e-02	0.559	-4.035	ZNF83	zinc finger protein 83	19	-57807429, -57807429	M27877	55769	19q13.3	Hs.467210 Hs.655934 Hs.659798 Hs.710125	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208949_s_at	0.318	9.829	2.133	4.959e-02	0.559	-4.035	LGALS3	lectin, galactoside-binding, soluble, 3	14	54665624, 54673658	BC001120	3958	14q21-q22	Hs.531081	162	skeletal system development protein binding sugar binding proteinaceous extracellular matrix nucleus cytoplasm plasma membrane IgE binding cell differentiation extracellular matrix organization
235260_s_at	-0.458	5.641	-2.133	4.959e-02	0.559	-4.035	PACRGL	PARK2 co-regulated-like	4	20311133	AA398590	133015	4p15.31	Hs.479298	5	binding
1560494_a_at	-0.141	1.748	-2.133	4.963e-02	0.559	-4.036	CPXCR1	CPX chromosome region, candidate 1	X	87888881	AK098646	53336	Xq21.3	Hs.458292	2	intracellular zinc ion binding
232172_at	0.202	4.887	2.133	4.964e-02	0.559	-4.036	LOC401577	hypothetical protein LOC401577	X, Y		AK023533	401577	Xp22.33 Yp11.31	Hs.444541	2
215894_at	0.223	2.872	2.132	4.967e-02	0.560	-4.037	PTGDR	prostaglandin D2 receptor (DP)	14	51804180	AI460323	5729	14q22.1	Hs.306831	36	prostaglandin J receptor activity receptor activity G-protein coupled receptor activity prostaglandin D receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane male sex determination	Neuroactive ligand-receptor interaction
218291_at	0.274	7.666	2.132	4.971e-02	0.560	-4.037	ROBLD3	roadblock domain containing 3	1	154291140	NM_014017	28956	1q22	Hs.632483	5	lysosome endosome membrane
203364_s_at	-0.174	6.764	-2.132	4.974e-02	0.560	-4.038	KIAA0652	KIAA0652	11	46595401	NM_014741	9776	11p11.2	Hs.127403	16
209555_s_at	-0.698	9.879	-2.131	4.975e-02	0.560	-4.038	CD36	CD36 molecule (thrombospondin receptor)	7	80069439, 80105767, 80105767, 80113580, 80113697	M98399	948	7q11.2	Hs.120949	173	positive regulation of cell-matrix adhesion low-density lipoprotein receptor activity membrane fraction Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process transport cell adhesion nitric oxide mediated signal transduction blood coagulation high-density lipoprotein binding lipid binding cell surface cell surface positive regulation of foam cell differentiation plasma membrane long-chain fatty acid transport lipid storage cGMP-mediated signaling cholesterol transport platelet alpha granule membrane lipoprotein particle clearance lipoprotein catabolic process lipoprotein transport apoptotic cell clearance transforming growth factor beta binding thrombospondin receptor activity	PPAR signaling pathway ECM-receptor interaction Hematopoietic cell lineage Adipocytokine signaling pathway
209041_s_at	0.323	7.119	2.131	4.977e-02	0.560	-4.038	UBE2G2	ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)	21	-45013382	BG395660	7327	21q22.3	Hs.529420 Hs.701398	19	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding cytosol ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
207122_x_at	0.313	6.548	2.131	4.977e-02	0.560	-4.038	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	16	-28510766, -28510766	NM_001054	6799	16p12.1	Hs.546304	25	aryl sulfotransferase activity cytoplasm catecholamine metabolic process lipid metabolic process steroid metabolic process amine biosynthetic process transferase activity	Sulfur metabolism
224636_at	-0.298	8.964	-2.130	4.985e-02	0.561	-4.040	ZFP91	zinc finger protein 91 homolog (mouse)	11	58103162	AL045405	80829	11q12	Hs.524920	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
222767_s_at	-0.227	5.714	-2.130	4.987e-02	0.561	-4.040	C12orf49	chromosome 12 open reading frame 49	12	-115637978	AW872378	79794	12q24.22	Hs.592011	2	extracellular region
218082_s_at	-0.241	7.293	-2.130	4.987e-02	0.561	-4.040	UBP1	upstream binding protein 1 (LBP-1a)	3	-33404831, -33404831	NM_014517	7342	3p22.3	Hs.643744	11	transcription factor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter negative regulation of transcription specific transcriptional repressor activity viral genome replication
206334_at	0.210	4.382	2.130	4.990e-02	0.561	-4.041	LIPF	lipase, gastric	10	90414073	NM_004190	8513	10q23.31	Hs.523130	25	triacylglycerol lipase activity protein binding extracellular region mitochondrion triglyceride metabolic process lipid binding lipid catabolic process malate dehydrogenase activity hydrolase activity	Glycerolipid metabolism Metabolic pathways
203606_at	0.216	10.304	2.130	4.990e-02	0.561	-4.041	NDUFS6	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)	5	1854508	NM_004553	4726	5p15.33	Hs.408257	15	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity electron carrier activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
219854_at	0.313	5.260	2.129	4.994e-02	0.561	-4.041	ZNF14	zinc finger protein 14	19	-19682280	NM_021030	7561	19p13.3-p13.2	Hs.659932	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204766_s_at	0.219	5.959	2.129	5.000e-02	0.562	-4.042	NUDT1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	7	2248382, 2248421, 2249065	NM_002452	4521	7p22	Hs.534331	46	GTPase activity protein binding cytoplasm DNA repair response to oxidative stress 8-oxo-7,8-dihydroguanine triphosphatase activity hydrolase activity

3810 Genes