Bioconductor Affymetrix Probe Listing

Probe	log2FC	AveExpr	t	P.Value	adj.P.Val	B	Symbol	Description	Chromosome	Chromosome Location	GenBank	Gene	Cytoband	UniGene	PubMed	Gene Ontology	Pathway
1556113_at	-1.191	5.615	-10.208	3.335e-08	0.002	8.276	DKFZp451A211	DKFZp451A211 protein	13		BC036906	400169	13q34	Hs.646609	1
242414_at	1.476	5.714	8.560	3.339e-07	0.004	6.467	QPRT	quinolinate phosphoribosyltransferase	16	29597941	AW960707	23475	16p11.2	Hs.513484	8	nicotinate-nucleotide diphosphorylase (carboxylating) activity nicotinate-nucleotide diphosphorylase (carboxylating) activity cellular_component cytosol metabolic process NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process quinolinate catabolic process protein homodimerization activity protein oligomerization	Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
209190_s_at	-1.006	7.858	-8.498	3.662e-07	0.004	6.391	DIAPH1	diaphanous homolog 1 (Drosophila)	5	-140874771	AF051782	1729	5q31	Hs.529451	33	actin binding receptor binding cytoplasm cytoskeleton plasma membrane sensory perception of sound cellular component organization Rho GTPase binding actin cytoskeleton organization ruffle membrane cell projection	Focal adhesion Regulation of actin cytoskeleton
237116_at	-2.245	7.747	-8.205	5.702e-07	0.005	6.028	LOC646903	hypothetical LOC646903	3		AI262277	646903	3q25.1	Hs.632559	1
224323_s_at	1.035	5.975	7.415	1.990e-06	0.011	4.981	MRO	maestro	18	-46575487, -46575487	AB042647	83876	18q21	Hs.30495	6	binding nucleus nucleolus
213572_s_at	-1.376	6.314	-7.389	2.075e-06	0.011	4.945	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	6	-2778732	AI554300	1992	6p25	Hs.381167	18	serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity
201975_at	-0.923	9.896	-7.386	2.086e-06	0.011	4.941	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	NM_002956	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
1557260_a_at	1.847	2.670	7.332	2.278e-06	0.011	4.866	ZNF382	zinc finger protein 382	19	41788060	BM973530	84911	19q13.12	Hs.631591	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214788_x_at	-3.035	7.439	-7.269	2.529e-06	0.011	4.777	DDN	dendrin	12	-47675199	AA731713	23109	12q13.12	Hs.591044	5	nucleus cytoplasm endoplasmic reticulum plasma membrane dendrite cell projection perikaryon
228044_at	0.860	5.006	7.220	2.741e-06	0.011	4.708	SERP2	stress-associated endoplasmic reticulum protein family member 2	13	43845977	AI420319	387923	13q14.11	Hs.377972	4	endoplasmic reticulum protein transport membrane integral to membrane intracellular protein transmembrane transport
211984_at	-1.217	10.402	-7.200	2.835e-06	0.011	4.679	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	AI653730	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
200655_s_at	-0.952	10.516	-7.180	2.929e-06	0.011	4.651	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	NM_006888	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
202763_at	-1.272	5.490	-7.057	3.598e-06	0.012	4.474	CASP3	caspase 3, apoptosis-related cysteine peptidase	4	-185785843	NM_004346	836	4q34	Hs.141125	552	B cell homeostasis release of cytochrome c from mitochondria cysteine-type endopeptidase activity cyclin-dependent protein kinase inhibitor activity protein binding nucleus nucleoplasm nucleolus cytoplasm mitochondrion cytosol cytosol plasma membrane DNA fragmentation involved in apoptosis proteolysis response to DNA damage stimulus heart development sensory perception of sound peptidase activity induction of apoptosis via death domain receptors induction of apoptosis by oxidative stress response to UV response to wounding keratinocyte differentiation nuclear fragmentation during apoptosis negative regulation of B cell proliferation response to tumor necrosis factor T cell homeostasis negative regulation of apoptosis cell fate commitment negative regulation of cyclin-dependent protein kinase activity negative regulation of activated T cell proliferation neuron apoptosis	MAPK signaling pathway p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Parkinson's disease Amyotrophic lateral sclerosis (ALS) Huntington's disease Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer
211985_s_at	-1.313	10.126	-6.975	4.131e-06	0.012	4.355	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	AI653730	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
222990_at	-0.759	9.423	-6.958	4.254e-06	0.012	4.330	UBQLN1	ubiquilin 1	9	-85464697	AW204104	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
202985_s_at	-0.859	6.914	-6.883	4.828e-06	0.012	4.220	BAG5	BCL2-associated athanogene 5	14	-103092641, -103092641, -103092641	NM_004873	9529	14q32.33	Hs.5443	10	protein binding protein folding apoptosis
228728_at	1.072	9.498	6.882	4.838e-06	0.012	4.219	C7orf58	chromosome 7 open reading frame 58	7	120415986, 120416680	BF724137	79974	7q31.31	Hs.189652	13	endoplasmic reticulum
238592_at	-3.092	8.949	-6.877	4.882e-06	0.012	4.211	PDLIM3	PDZ and LIM domain 3	4	-186659844	BE840636	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
222975_s_at	-1.126	10.872	-6.840	5.197e-06	0.012	4.157	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	AI423180	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
210967_x_at	-0.783	9.549	-6.820	5.380e-06	0.012	4.126	CACNB1	calcium channel, voltage-dependent, beta 1 subunit	17	-34586914, -34583234	M92301	782	17q21-q22	Hs.635	18	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
225337_at	-0.814	6.878	-6.698	6.634e-06	0.014	3.944	ABHD2	abhydrolase domain containing 2	15	87432384	AI346910	11057	15q26.1	Hs.122337 Hs.705984	10	molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration
204044_at	1.394	5.567	6.658	7.116e-06	0.014	3.883	QPRT	quinolinate phosphoribosyltransferase	16	29597941	NM_014298	23475	16p11.2	Hs.513484	8	nicotinate-nucleotide diphosphorylase (carboxylating) activity nicotinate-nucleotide diphosphorylase (carboxylating) activity cellular_component cytosol metabolic process NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process quinolinate catabolic process protein homodimerization activity protein oligomerization	Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
223852_s_at	-1.084	7.293	-6.638	7.365e-06	0.014	3.853	STK40	serine/threonine kinase 40	1	-36577811	BC005169	83931	1p34.3	Hs.471768	11	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity
209563_x_at	-0.915	11.120	-6.636	7.384e-06	0.014	3.851	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	BC000454	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
239035_at	0.699	6.290	6.633	7.429e-06	0.014	3.846	MTHFR	5,10-methylenetetrahydrofolate reductase (NADPH)	1	-11768373	AL138431	4524	1p36.3	Hs.214142	1776	methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction	One carbon pool by folate Methane metabolism Metabolic pathways
206996_x_at	-0.760	9.524	-6.625	7.530e-06	0.014	3.834	CACNB1	calcium channel, voltage-dependent, beta 1 subunit	17	-34586914, -34583234	NM_000723	782	17q21-q22	Hs.635	18	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
235070_at	-0.935	8.267	-6.553	8.532e-06	0.015	3.725	A2BP1	ataxin 2-binding protein 1	16	6009132, 6763810, 7322751	AL133898	54715	16p13.3	Hs.459842	22	nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport
217911_s_at	-0.828	10.389	-6.470	9.878e-06	0.016	3.596	BAG3	BCL2-associated athanogene 3	10	121400871	NM_004281	9531	10q25.2-q26.2	Hs.523309	37	protein binding cellular_component cytosol protein folding anti-apoptosis
219765_at	2.239	4.909	6.464	9.989e-06	0.016	3.586	ZNF329	zinc finger protein 329	19	-63329506	NM_024620	79673	19q13.43	Hs.458377	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225185_at	-1.186	7.857	-6.452	1.019e-05	0.016	3.569	MRAS	muscle RAS oncogene homolog	3	139549314, 139550197	BF343625	22808	3q22.3	Hs.527021	18	nucleotide binding GTPase activity GTP binding intracellular plasma membrane Ras protein signal transduction multicellular organismal development muscle organ development actin cytoskeleton organization GTP-dependent protein binding	MAPK signaling pathway Tight junction Regulation of actin cytoskeleton
224983_at	-0.803	9.933	-6.439	1.043e-05	0.016	3.549	SCARB2	scavenger receptor class B, member 2	4	-77298917	BF339821	950	4q21.1	Hs.349656 Hs.714206	24	receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane	Lysosome
231968_at	-0.914	7.931	-6.365	1.188e-05	0.018	3.434	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1	2	128565223, 128565251	AK025416	56886	2q14.3	Hs.598715 Hs.719174	10	UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding
208649_s_at	-0.742	8.396	-6.328	1.270e-05	0.019	3.375	VCP	valosin-containing protein	9	-35046064	AF100752	7415	9p13.3	Hs.529782	97	nucleotide binding ATP binding nucleus nucleus nucleolus cytoplasm endoplasmic reticulum microsome cytosol double-strand break repair transport activation of caspase activity response to DNA damage stimulus lipid binding protein ubiquitination hydrolase activity ATPase activity protein domain specific binding modification-dependent protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol regulation of apoptosis establishment of protein localization
223016_x_at	-1.184	7.617	-6.318	1.293e-05	0.019	3.360	ZRANB2	zinc finger, RAN-binding domain containing 2	1	-71301561	AF065392	9406	1p31	Hs.194718	18	transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding
227558_at	1.105	6.002	6.254	1.450e-05	0.020	3.258	CBX4	chromobox homolog 4 (Pc class homolog, Drosophila)	17	-75421549	AI570531	8535	17q25.3	Hs.714363	25	chromatin chromatin binding transcription corepressor activity nucleus chromatin assembly or disassembly anti-apoptosis negative regulation of transcription chromatin modification enzyme binding modification-dependent protein catabolic process
217963_s_at	1.474	8.334	6.205	1.583e-05	0.021	3.181	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	X	102517923, 102518764	NM_014380	27018	Xq22.2	Hs.448588 Hs.719133	17	protein binding nucleus cytoplasm apoptosis multicellular organismal development metal ion binding	Neurotrophin signaling pathway
202693_s_at	-1.361	5.990	-6.184	1.643e-05	0.021	3.148	STK17A	serine/threonine kinase 17a	7	43589216	AW194730	9263	7p12-p14	Hs.709489	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity
228555_at	-0.965	6.532	-6.174	1.671e-05	0.021	3.133	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	4	-114597792, -114591638	AA029441	817	4q26	Hs.144114	29	G1/S transition of mitotic cell cycle nucleotide binding regulation of cell growth calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm calcium- and calmodulin-dependent protein kinase complex calcium ion transport transferase activity T-tubule protein amino acid autophosphorylation cardiac muscle contraction	ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma
239084_at	-0.803	4.907	-6.174	1.673e-05	0.021	3.132	SNAP29	synaptosomal-associated protein, 29kDa	22	19543291	BE896490	9342	22q11.21	Hs.108002 Hs.701035	19	SNAP receptor activity cytoplasm plasma membrane exocytosis vesicle targeting membrane fusion protein transport synaptosome cell junction synapse	SNARE interactions in vesicular transport
212678_at	-0.725	5.639	-6.115	1.861e-05	0.022	3.037	NF1	neurofibromin 1	17	26446120, 26446120	AW054826	4763	17q11.2	Hs.113577	204	osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction	MAPK signaling pathway
206209_s_at	0.852	6.436	6.107	1.888e-05	0.022	3.025	CA4	carbonic anhydrase IV	17	55582083	NM_000717	762	17q23	Hs.89485	30	carbonate dehydratase activity membrane fraction plasma membrane one-carbon metabolic process visual perception zinc ion binding lyase activity anchored to membrane metal ion binding response to stimulus	Nitrogen metabolism
219073_s_at	1.772	4.964	6.106	1.891e-05	0.022	3.023	OSBPL10	oxysterol binding protein-like 10	3	-31677320	NM_017784	114884	3p22.3	Hs.150122	7	lipid transport steroid metabolic process
201724_s_at	-0.766	6.968	-6.043	2.122e-05	0.023	2.921	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	NM_020474	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
202694_at	-0.821	4.352	-6.037	2.142e-05	0.023	2.913	STK17A	serine/threonine kinase 17a	7	43589216	AW183478	9263	7p12-p14	Hs.709489	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity
226648_at	-0.987	6.811	-6.020	2.211e-05	0.023	2.885	HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	10	102285630	AI769745	55662	10q24	Hs.500788	30	peptide-aspartate beta-dioxygenase activity iron ion binding protein binding nucleus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
228332_s_at	-0.579	9.953	-6.016	2.226e-05	0.023	2.878	C11orf31	chromosome 11 open reading frame 31	11	57265297	AA526939	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
224630_at	-0.680	7.942	-6.006	2.266e-05	0.023	2.863	ERLEC1	endoplasmic reticulum lectin 1	2	53867571	AK001913	27248	2p16.2	Hs.438336 Hs.713845	10	protein binding endoplasmic reticulum endoplasmic reticulum lumen
204992_s_at	-1.296	10.321	-5.976	2.397e-05	0.023	2.813	PFN2	profilin 2	3	-151165380	NM_002628	5217	3q25.1-q25.2	Hs.91747	24	actin binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm regulation of actin polymerization or depolymerization actin cytoskeleton actin cytoskeleton organization	Regulation of actin cytoskeleton
202492_at	-0.694	7.642	-5.966	2.439e-05	0.023	2.797	ATG9A	ATG9 autophagy related 9 homolog A (S. cerevisiae)	2	-219792345	NM_024085	79065	2q35	Hs.323363	10	autophagic vacuole formation autophagy protein transport membrane integral to membrane cytoplasmic vesicle
243924_at	1.499	3.740	5.950	2.512e-05	0.023	2.771	LOC100127980	hypothetical protein LOC100127980	19		AA781404	100127980	19q13.12	Hs.595153	1
1554292_a_at	-0.601	3.121	-5.947	2.527e-05	0.023	2.766	UHRF1BP1L	UHRF1 binding protein 1-like	12	-98987816, -98954993	BC014891	23074	12q23.1	Hs.620701	2
238613_at	-1.034	9.818	-5.925	2.630e-05	0.023	2.730	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AI475164	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
228153_at	-1.100	9.778	-5.924	2.636e-05	0.023	2.728	RNF144B	ring finger protein 144B	6	18495572	AI953847	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
218178_s_at	-1.250	8.778	-5.915	2.678e-05	0.023	2.714	CHMP1B	chromatin modifying protein 1B	18	11841388	NM_020412	57132	18p11.21	Hs.656244	16	cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division	Endocytosis
200758_s_at	-0.882	11.205	-5.853	3.005e-05	0.025	2.611	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	AI361227	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
225894_at	-1.030	11.477	-5.852	3.010e-05	0.025	2.610	SYNPO2	synaptopodin 2	4	120029443, 120029443	AL589603	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
214657_s_at	-1.212	5.063	-5.843	3.058e-05	0.025	2.596	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AU134977	283131	11q13.1	Hs.523789 Hs.648467	6
224324_at	0.823	5.004	5.839	3.083e-05	0.025	2.588	MRO	maestro	18	-46575487, -46575487	AB042647	83876	18q21	Hs.30495	6	binding nucleus nucleolus
225999_at	-1.125	5.149	-5.806	3.274e-05	0.026	2.535	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AI743612	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
204067_at	0.719	7.561	5.797	3.329e-05	0.026	2.520	SUOX	sulfite oxidase	12	54677309	AA129776	6821	12q13.2	Hs.558403	23	mitochondrion mitochondrial intermembrane space cytosol response to nutrient sulfite oxidase activity electron carrier activity oxidoreductase activity heme binding molybdenum ion binding molybdopterin cofactor binding metal ion binding oxidation reduction	Sulfur metabolism
214643_x_at	-0.915	9.148	-5.789	3.382e-05	0.026	2.506	BIN1	bridging integrator 1	2	-127522077, -127522076	BG034080	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
200789_at	0.897	10.678	5.771	3.492e-05	0.026	2.477	ECH1	enoyl Coenzyme A hydratase 1, peroxisomal	19	-43997901	NM_001398	1891	19q13.1	Hs.196176	9	enoyl-CoA hydratase activity protein binding mitochondrion peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process isomerase activity	Tyrosine metabolism
218858_at	-1.393	9.627	-5.759	3.575e-05	0.026	2.456	DEPDC6	DEP domain containing 6	8	120955080	NM_022783	64798	8q24.12	Hs.112981	11	protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size
232183_at	-0.803	6.202	-5.756	3.590e-05	0.026	2.452	SERAC1	serine active site containing 1	6	-158450523	AA128978	84947	6q25.3	Hs.154706	6	binding membrane integral to membrane
229160_at	-1.576	7.231	-5.756	3.596e-05	0.026	2.451	MUM1L1	melanoma associated antigen (mutated) 1-like 1	X	105307974	AI967987	139221	Xq22.3	Hs.592221	5
202204_s_at	-0.830	7.366	-5.748	3.644e-05	0.026	2.439	AMFR	autocrine motility factor receptor	16	-54952864	AF124145	267	16q21	Hs.295137	33	protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization
209029_at	-0.770	7.786	-5.743	3.681e-05	0.026	2.430	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	12	6703410, 6703440, 6703505, 6703709	AF193844	50813	12p13.31	Hs.530823	16	nucleus cytoplasm signalosome
220183_s_at	0.990	6.738	5.716	3.868e-05	0.026	2.386	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	4	-124033248, -124033248	NM_007083	11162	4q26	Hs.558459	15	cellular_component growth factor activity biological_process hydrolase activity
204270_at	0.622	6.165	5.703	3.969e-05	0.026	2.362	SKI	v-ski sarcoma viral oncogene homolog (avian)	1	2149993	AI568728	6497	1q22-q24	Hs.663133	54	nucleotide binding protein binding nucleus nucleoplasm cell differentiation BMP signaling pathway
220703_at	2.137	7.471	5.692	4.047e-05	0.026	2.345	C10orf110	chromosome 10 open reading frame 110	10	1058576	NM_018470	55853	10p15.3	Hs.644603	2
226066_at	-0.873	8.536	-5.681	4.130e-05	0.027	2.327	MITF	microphthalmia-associated transcription factor	3	69871322, 69895651, 69998131, 70010945, 70068442	AL117653	4286	3p14.2-p14.1	Hs.166017 Hs.618266	93	DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation	Melanogenesis Pathways in cancer Melanoma
222569_at	-1.301	6.279	-5.653	4.354e-05	0.027	2.279	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1	2	128565223, 128565251	AU153746	56886	2q14.3	Hs.598715 Hs.719174	10	UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding
225192_at	-0.860	7.570	-5.645	4.420e-05	0.027	2.266	C10orf46	chromosome 10 open reading frame 46	10	-120430483	AA044726	143384	10q26.11	Hs.719193	4	ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding
222154_s_at	-1.070	9.172	-5.614	4.683e-05	0.028	2.214	SPATS2L	spermatogenesis associated, serine-rich 2-like	2	200878848, 200879229, 200879600	AK002064	26010	2q33.1	Hs.120323	9
240453_at	-1.009	3.262	-5.611	4.710e-05	0.028	2.209	C20orf26	chromosome 20 open reading frame 26	20	19981195	AA418538	26074	20p11.23	Hs.176013	6
227337_at	-1.598	7.241	-5.610	4.718e-05	0.028	2.207	ANKRD37	ankyrin repeat domain 37	4	186554833	AA886870	353322	4q35.1	Hs.508154	4	nucleus cytoplasm
224281_s_at	-0.640	9.795	-5.601	4.801e-05	0.028	2.192	NGRN	neugrin, neurite outgrowth associated	15	88609898	AF225423	51335	15q26.1	Hs.715556 Hs.716378	2	molecular_function nucleus multicellular organismal development nervous system development neuron differentiation
226280_at	-0.717	8.481	-5.601	4.803e-05	0.028	2.191	BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	15	-57742353	AA133277	663	15q22.2	Hs.646490	15	GTPase activator activity calcium ion binding protein binding nuclear envelope cytoplasm apoptosis anti-apoptosis intracellular membrane-bounded organelle perinuclear region of cytoplasm
223805_at	-1.090	8.468	-5.580	4.990e-05	0.028	2.157	OSBPL6	oxysterol binding protein-like 6	2	178767619, 178893216	AF323728	114880	2q31-q32.1	Hs.318775	7	lipid transport steroid metabolic process
224709_s_at	-0.770	6.971	-5.573	5.063e-05	0.029	2.144	CDC42SE2	CDC42 small effector 2	5	130627600	AF131831	56990	5q23.3-q31.1	Hs.508829 Hs.713870	8	structural molecule activity protein binding cytoplasm cytoskeleton plasma membrane phagocytosis regulation of cell shape regulation of signal transduction
242274_x_at	0.993	4.133	5.563	5.156e-05	0.029	2.128	SLC25A42	solute carrier family 25, member 42	19	19035807	AI057363	284439	19p13.11	Hs.303669	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
203580_s_at	-0.880	8.015	-5.548	5.299e-05	0.029	2.103	SLC7A6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6	16	66855923	NM_003983	9057	16q22.1	Hs.653193 Hs.709557	6	plasma membrane integral to plasma membrane protein complex assembly cellular amino acid metabolic process transport amino acid transport amino acid transmembrane transporter activity antiporter activity
217820_s_at	-1.286	8.103	-5.543	5.352e-05	0.029	2.094	ENAH	enabled homolog (Drosophila)	1	-223741156	NM_018212	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
205311_at	1.072	4.213	5.513	5.662e-05	0.031	2.043	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7	-50493627, -50493627	NM_000790	1644	7p12.2	Hs.359698	48	aromatic-L-amino-acid decarboxylase activity protein binding cellular amino acid and derivative metabolic process response to toxin lyase activity carboxylic acid metabolic process pyridoxal phosphate binding catecholamine biosynthetic process	Histidine metabolism Tyrosine metabolism Phenylalanine metabolism Tryptophan metabolism Isoquinoline alkaloid biosynthesis Betalain biosynthesis Biosynthesis of alkaloids derived from shikimate pathway Metabolic pathways
221027_s_at	1.127	8.404	5.509	5.707e-05	0.031	2.036	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	NM_030821	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
201471_s_at	-0.722	9.615	-5.494	5.878e-05	0.031	2.010	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	NM_003900	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
1553177_at	-2.274	6.108	-5.492	5.896e-05	0.031	2.007	SH2D1B	SH2 domain containing 1B	1	-160631679	BC022407	117157	1q23.3	Hs.350581	10	molecular_function protein binding cellular_component biological_process	Natural killer cell mediated cytotoxicity
214439_x_at	-0.903	10.906	-5.458	6.286e-05	0.032	1.949	BIN1	bridging integrator 1	2	-127522077, -127522076	AF043899	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
212566_at	-0.754	10.545	-5.458	6.292e-05	0.032	1.948	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AL523310	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
59625_at	-0.539	7.889	-5.436	6.553e-05	0.033	1.912	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	16	65765370	AI912351	8996	16q21-q23	Hs.513667	22	RNA binding intracellular nucleus nucleolus cytoplasm cytosol mRNA processing anti-apoptosis RNA splicing identical protein binding regulation of apoptosis
218211_s_at	0.981	7.239	5.436	6.560e-05	0.033	1.911	MLPH	melanophilin	2	238060616	NM_024101	79083	2q37.3	Hs.102406	23	protein binding cytoplasm intracellular protein transport zinc ion binding Rab GTPase binding metal ion binding
223680_at	0.621	3.733	5.434	6.575e-05	0.033	1.909	ZNF607	zinc finger protein 607	19	-42879115	BC005085	84775	19q13.1	Hs.116622	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204309_at	0.670	4.458	5.428	6.656e-05	0.033	1.898	CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	15	-72417155, -72417155	NM_000781	1583	15q23-q24	Hs.303980	88	monooxygenase activity mitochondrion lipid metabolic process C21-steroid hormone biosynthetic process cholesterol metabolic process cholesterol metabolic process cholesterol monooxygenase (side-chain-cleaving) activity cholesterol monooxygenase (side-chain-cleaving) activity electron carrier activity membrane heme binding mitochondrial membrane vitamin D metabolic process metal ion binding oxidation reduction	C21-Steroid hormone metabolism Metabolic pathways
225243_s_at	-1.239	8.469	-5.424	6.708e-05	0.033	1.891	SLMAP	sarcolemma associated protein	3	57718213	AB046821	7871	3p21.2-p14.3	Hs.476432	11	smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding
214033_at	-0.870	5.924	-5.415	6.826e-05	0.033	1.875	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	16	-16222544, -16150922	AI084637	368	16p13.1	Hs.442182	70	nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus	ABC transporters
201462_at	0.989	4.520	5.414	6.829e-05	0.033	1.874	SCRN1	secernin 1	7	-29926244, -29926244, -29926244	NM_014766	9805	7p14.3-p14.1	Hs.520740	11	molecular_function nucleus cytoplasm exocytosis nuclear membrane
222478_at	-0.771	7.940	-5.399	7.028e-05	0.033	1.849	VPS36	vacuolar protein sorting 36 homolog (S. cerevisiae)	13	-51884737	AL576924	51028	13q14.3	Hs.109520	11	nucleus cytoplasm lysosome late endosome lipid binding protein transport ubiquitin binding regulation of transcription	Endocytosis
211654_x_at	0.807	6.355	5.395	7.092e-05	0.033	1.840	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M17565	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
1556114_a_at	-1.072	9.046	-5.392	7.122e-05	0.033	1.837	DKFZp451A211	DKFZp451A211 protein	13		BC036906	400169	13q34	Hs.646609	1
225817_at	0.753	4.119	5.385	7.229e-05	0.033	1.823	CGNL1	cingulin-like 1	15	55455996	AB051536	84952	15q21.3	Hs.148989	6	motor activity tight junction myosin complex cell junction
221959_at	-0.694	5.923	-5.374	7.380e-05	0.033	1.804	FAM110B	family with sequence similarity 110, member B	8	59069666	BE672313	90362	8q12.1	Hs.154652	7	cytoplasm mitochondrion centrosome
212539_at	-0.810	7.260	-5.374	7.381e-05	0.033	1.804	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	AI422099	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
221511_x_at	-0.738	7.859	-5.369	7.445e-05	0.033	1.797	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AB033080	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
212610_at	-0.936	10.103	-5.354	7.660e-05	0.034	1.771	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	U79291	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
226982_at	-1.237	5.535	-5.352	7.696e-05	0.034	1.767	ELL2	elongation factor, RNA polymerase II, 2	5	-95246557	AI745624	22936	5q15	Hs.192221 Hs.708710	6	RNA polymerase II transcription factor activity nucleus RNA elongation from RNA polymerase II promoter transcription elongation factor complex RNA polymerase II transcription elongation factor activity regulation of transcription
204285_s_at	-1.309	4.893	-5.337	7.922e-05	0.034	1.740	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	18	55718171	AI857639	5366	18q21.32	Hs.96	36	release of cytochrome c from mitochondria protein binding mitochondrion induction of apoptosis activation of caspase activity cell structure disassembly during apoptosis virus-infected cell apoptosis response to dsRNA	p53 signaling pathway
238575_at	-0.979	7.166	-5.330	8.021e-05	0.034	1.729	OSBPL6	oxysterol binding protein-like 6	2	178767619, 178893216	AI094626	114880	2q31-q32.1	Hs.318775	7	lipid transport steroid metabolic process
210202_s_at	-1.109	10.258	-5.322	8.140e-05	0.034	1.716	BIN1	bridging integrator 1	2	-127522077, -127522076	U87558	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
200653_s_at	-0.811	10.801	-5.322	8.145e-05	0.034	1.715	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	M27319	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
217759_at	-0.497	6.964	-5.319	8.190e-05	0.034	1.710	TRIM44	tripartite motif-containing 44	11	35640928	BF431488	54765	11p13	Hs.192103	10	intracellular zinc ion binding metal ion binding
200836_s_at	-0.868	8.420	-5.307	8.391e-05	0.035	1.688	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	NM_002375	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
225721_at	-1.457	8.704	-5.303	8.445e-05	0.035	1.683	SYNPO2	synaptopodin 2	4	120029443, 120029443	AI658662	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
218364_at	-1.021	8.099	-5.303	8.448e-05	0.035	1.682	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	NM_017724	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
212666_at	-0.853	5.449	-5.295	8.575e-05	0.035	1.669	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	7	-98462999	AB046845	57154	7q22.1	Hs.189329	34	ubiquitin-protein ligase activity protein binding intracellular cytoplasm plasma membrane protein modification process protein export from nucleus ectoderm development ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation negative regulation of ossification negative regulation of BMP signaling pathway ubiquitin-dependent SMAD protein catabolic process positive regulation of protein ubiquitination receptor catabolic process protein localization at cell surface protein ubiquitination during ubiquitin-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process activin binding I-SMAD binding R-SMAD binding	Ubiquitin mediated proteolysis Endocytosis TGF-beta signaling pathway
212168_at	-0.737	5.686	-5.292	8.627e-05	0.035	1.663	RBM12	RNA binding motif protein 12	20	-33700292	AL514547	10137	20q11.21	Hs.246413	13	nucleotide binding RNA binding protein binding nucleus
209075_s_at	-0.686	11.329	-5.285	8.746e-05	0.035	1.651	ISCU	iron-sulfur cluster scaffold homolog (E. coli)	12	107480423	AY009128	23479	12q24.1	Hs.615131	14	iron ion binding nucleus cytoplasm mitochondrion cytosol nitrogen fixation iron-sulfur cluster assembly protein complex scaffold metal ion binding iron-sulfur cluster binding
200721_s_at	-0.668	7.848	-5.282	8.800e-05	0.035	1.645	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	10	-104228976	NM_005736	10121	10q24.32	Hs.153961	26	nucleotide binding protein binding ATP binding cytoplasm centrosome cytoskeleton dynactin complex vesicle-mediated transport
210716_s_at	-1.379	7.410	-5.281	8.820e-05	0.035	1.643	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	M97501	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
206030_at	1.019	8.060	5.276	8.895e-05	0.035	1.636	ASPA	aspartoacylase (Canavan disease)	17	3324153, 3326045	NM_000049	443	17pter-p13	Hs.171142	27	aminoacylase activity nucleus cytoplasm aspartate catabolic process metabolic process zinc ion binding hydrolase activity, acting on ester bonds aspartoacylase activity metal ion binding	Alanine, aspartate and glutamate metabolism Histidine metabolism
224558_s_at	-1.231	9.293	-5.270	9.009e-05	0.035	1.624	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AI446756	378938	11q13.1	Hs.642877 Hs.714394	8
242287_at	-1.258	6.343	-5.259	9.194e-05	0.035	1.606	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	AI090487	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
244552_at	0.494	3.580	5.256	9.251e-05	0.035	1.600	ZNF788	zinc finger family member 788	19	12064077	AI190287	388507	19p13.2	Hs.127473		DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1556121_at	-1.360	6.152	-5.251	9.335e-05	0.035	1.592	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AK021751	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
221931_s_at	-0.877	8.078	-5.249	9.367e-05	0.035	1.589	SEH1L	SEH1-like (S. cerevisiae)	18	12937982	AV701173	81929	18p11.21	Hs.301048	9	kinetochore nucleus nuclear pore organization mitotic metaphase plate congression protein transport Nup107-160 complex Nup107-160 complex mRNA transport attachment of spindle microtubules to kinetochore during mitosis intracellular protein transmembrane transport
1565254_s_at	-0.464	4.196	-5.247	9.405e-05	0.035	1.585	ELL	elongation factor RNA polymerase II	19	-18414473	AF272374	8178	19p13.1	Hs.515260	26	protein binding nucleus nucleoplasm RNA elongation from RNA polymerase II promoter transcription elongation factor complex positive transcription elongation factor activity Cajal body nuclear speck RNA polymerase II transcription elongation factor activity regulation of transcription
212567_s_at	-0.729	8.340	-5.247	9.411e-05	0.035	1.585	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AL523310	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
207757_at	0.846	4.480	5.237	9.590e-05	0.036	1.568	ZFP2	zinc finger protein 2 homolog (mouse)	5	178255521	NM_030613	80108	5q35.3	Hs.654533	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
224339_s_at	-1.351	6.257	-5.227	9.786e-05	0.036	1.549	ANGPTL1	angiopoietin-like 1	1	-177085292	AB056476	9068	1q25.2	Hs.591474	19	receptor binding extracellular region extracellular space signal transduction
231569_at	0.610	3.402	5.218	9.942e-05	0.036	1.535	TMEM31	transmembrane protein 31	X	102852492	N58489	203562	Xq22.2	Hs.98843	1	membrane integral to membrane
202222_s_at	-0.680	11.468	-5.212	1.006e-04	0.036	1.525	DES	desmin	2	219991342	NM_001927	1674	2q35	Hs.594952	57	structural constituent of cytoskeleton protein binding intracellular insoluble fraction cytoplasm cytoskeleton muscle contraction cytoskeleton organization regulation of heart contraction Z disc sarcolemma contractile fiber type III intermediate filament synapse	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
209287_s_at	-0.637	6.135	-5.186	1.059e-04	0.038	1.478	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	2	-37724246	AF104857	10602	2p21	Hs.369574	17	protein binding cytoskeletal regulatory protein binding cytoplasm signal transduction regulation of cell shape actin cytoskeleton membrane
222434_at	-1.249	5.829	-5.185	1.060e-04	0.038	1.477	ENAH	enabled homolog (Drosophila)	1	-223741156	AI963713	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
214999_s_at	-1.058	4.533	-5.164	1.105e-04	0.039	1.439	RAB11FIP3	RAB11 family interacting protein 3 (class II)	16	415668, 464850	AW243089	9727	16p13.3	Hs.531642	18	calcium ion binding protein binding protein transport membrane Rab GTPase binding recycling endosome	Endocytosis
202931_x_at	-0.849	10.850	-5.163	1.106e-04	0.039	1.438	BIN1	bridging integrator 1	2	-127522077, -127522076	NM_004305	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
200759_x_at	-0.787	11.280	-5.162	1.108e-04	0.039	1.437	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	NM_003204	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
224928_at	-0.867	9.894	-5.158	1.118e-04	0.039	1.429	SETD7	SET domain containing (lysine methyltransferase) 7	4	-140646641	AK024846	80854	4q28	Hs.480792	21	protein binding nucleus chromosome regulation of transcription, DNA-dependent methyltransferase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity	Lysine degradation
218676_s_at	-0.731	6.714	-5.156	1.121e-04	0.039	1.426	PCTP	phosphatidylcholine transfer protein	17	51183354	NM_021213	58488	17q21-q24	Hs.285218	9	cytoplasm cytosol cytosol lipid binding phosphatidylcholine transmembrane transporter activity phosphatidylcholine transmembrane transporter activity phospholipid transport phosphatidylcholine binding
213844_at	0.743	6.527	5.156	1.122e-04	0.039	1.425	HOXA5	homeobox A5	7	-27147520	NM_019102	3202	7p15-p14	Hs.655218	32	transcription factor activity nucleus regulation of transcription, DNA-dependent pattern specification process anterior/posterior pattern formation lung development thyroid gland development multicellular organism growth sequence-specific DNA binding embryonic skeletal system morphogenesis
227321_at	-1.388	7.016	-5.153	1.129e-04	0.039	1.420	GATS	GATS, stromal antigen 3 opposite strand	7	-99644496, -99636215	D52585	352954	7q22.1	Hs.556063 Hs.718406	4
223960_s_at	-0.679	6.790	-5.141	1.154e-04	0.039	1.400	C16orf5	chromosome 16 open reading frame 5	16	-4500677	AF195661	29965	16p13.3	Hs.654653	6	molecular_function nucleus apoptosis induction of apoptosis biological_process tumor necrosis factor-mediated signaling pathway DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
204976_s_at	-0.684	5.380	-5.138	1.162e-04	0.039	1.394	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	X	-109324069	AK023637	9949	Xq22.3	Hs.656243	7	molecular_function cellular_component biological_process
210201_x_at	-0.859	10.934	-5.137	1.165e-04	0.039	1.392	BIN1	bridging integrator 1	2	-127522077, -127522076	AF001383	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
229012_at	0.737	5.291	5.132	1.174e-04	0.039	1.384	C9orf24	chromosome 9 open reading frame 24	9	-34369016, -34369016	AW269443	84688	9p13.3	Hs.50334	8
209448_at	-1.087	6.969	-5.131	1.178e-04	0.039	1.381	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	BC002439	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
201538_s_at	-0.947	7.274	-5.128	1.184e-04	0.039	1.376	DUSP3	dual specificity phosphatase 3	17	-39199014	NM_004090	1845	17q21	Hs.181046	21	protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleoplasm protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity	MAPK signaling pathway
221232_s_at	-3.531	9.431	-5.122	1.199e-04	0.039	1.365	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	10	99322245	NM_020349	26287	10q23.31-q23.32	Hs.73708	17	muscle organ development structural constituent of muscle I band
1553971_a_at	-1.573	6.969	-5.116	1.211e-04	0.039	1.356	GATS	GATS, stromal antigen 3 opposite strand	7	-99644496, -99636215	AL831967	352954	7q22.1	Hs.556063 Hs.718406	4
224677_x_at	-0.583	8.682	-5.098	1.255e-04	0.039	1.324	C11orf31	chromosome 11 open reading frame 31	11	57265297	AV729234	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
201832_s_at	-0.817	9.929	-5.096	1.259e-04	0.039	1.321	USO1	USO1 homolog, vesicle docking protein (yeast)	4	76868852	NM_003715	8615	4q21.1	Hs.292689	34	Golgi membrane protein binding cytoplasm microsome Golgi apparatus cytosol intracellular protein transport protein transporter activity membrane vesicle-mediated transport vesicle fusion with Golgi apparatus perinuclear region of cytoplasm
225057_at	-0.950	7.770	-5.096	1.261e-04	0.039	1.320	SLC15A4	solute carrier family 15, member 4	12	-127843692	AI636759	121260	12q24.32-q24.33	Hs.507260 Hs.699387	6	transporter activity oligopeptide transport protein transport symporter activity membrane integral to membrane
201375_s_at	-0.674	10.090	-5.094	1.265e-04	0.039	1.317	PPP2CB	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	8	-30762667	NM_004156	5516	8p12	Hs.491440	40	protein phosphatase type 2A complex chromosome, centromeric region protein serine/threonine phosphatase activity iron ion binding protein binding nucleus cytoplasm spindle protein amino acid dephosphorylation regulation of gene expression hydrolase activity manganese ion binding response to hydrogen peroxide negative regulation of apoptosis proteasomal ubiquitin-dependent protein catabolic process response to antibiotic metal ion binding	Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression
223192_at	0.596	8.030	5.093	1.266e-04	0.039	1.316	SLC25A28	solute carrier family 25, member 28	10	-101360264	AF267854	81894	10q23-q24	Hs.403790	6	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
223373_s_at	0.884	8.632	5.093	1.267e-04	0.039	1.315	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AF306567	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
205902_at	-1.014	6.119	-5.087	1.283e-04	0.040	1.304	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1	-152946536, -152946536	AJ251016	3782	1q21.3	Hs.490765	40	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
225720_at	-1.641	8.371	-5.080	1.299e-04	0.040	1.293	SYNPO2	synaptopodin 2	4	120029443, 120029443	AW009747	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
218273_s_at	1.663	7.566	5.077	1.308e-04	0.040	1.286	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	8	94998258, 94998337, 94998350, 94998454, 94999167	NM_018444	54704	8q22.1	Hs.22265	19	magnesium ion binding protein serine/threonine phosphatase activity [pyruvate dehydrogenase (lipoamide)] phosphatase activity calcium ion binding mitochondrion mitochondrial matrix protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity
201935_s_at	-1.485	7.842	-5.076	1.310e-04	0.040	1.285	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	1	-21005560	AI768122	8672	1p36.12	Hs.467084	19	RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
231045_x_at	-0.583	8.514	-5.074	1.316e-04	0.040	1.281	C11orf31	chromosome 11 open reading frame 31	11	57265297	H29876	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
217924_at	-0.758	6.187	-5.071	1.322e-04	0.040	1.277	C6orf106	chromosome 6 open reading frame 106	6	-34663047	AL523965	64771	6p21.31	Hs.643498	10
214179_s_at	-0.850	10.811	-5.055	1.364e-04	0.040	1.248	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	H93013	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
219882_at	-0.891	5.188	-5.055	1.365e-04	0.040	1.247	TTLL7	tubulin tyrosine ligase-like family, member 7	1	-84107644	NM_024686	79739	1p31.1	Hs.445826	7	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process multicellular organismal development nervous system development ligase activity cell differentiation dendrite perikaryon
217551_at	0.797	3.983	5.053	1.369e-04	0.040	1.245	LOC441453	similar to olfactory receptor, family 7, subfamily A, member 17	11		AA719797	441453	11p15.1	Hs.523504	1
228084_at	0.905	7.162	5.052	1.372e-04	0.040	1.243	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AI767751	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
232704_s_at	-0.838	6.347	-5.046	1.390e-04	0.040	1.231	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	AK025207	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
204607_at	4.074	7.980	5.039	1.408e-04	0.041	1.219	HMGCS2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	1	-120092525	NM_005518	3158	1p13-p12	Hs.59889	13	hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity mitochondrion mitochondrial inner membrane mitochondrial matrix cholesterol biosynthetic process response to nutrient metabolic process isoprenoid biosynthetic process transferase activity response to drug response to peptide hormone stimulus	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
202203_s_at	-1.234	7.181	-5.036	1.417e-04	0.041	1.214	AMFR	autocrine motility factor receptor	16	-54952864	NM_001144	267	16q21	Hs.295137	33	protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization
235635_at	-0.746	5.358	-5.035	1.419e-04	0.041	1.213	ARHGAP5	Rho GTPase activating protein 5	14	31616245	N50119	394	14q12	Hs.592313	19	GTPase activity GTPase activator activity Rho GTPase activator activity GTP binding intracellular cytoplasm cell adhesion signal transduction small GTPase mediated signal transduction Rho protein signal transduction membrane SH2 domain binding	Focal adhesion Leukocyte transendothelial migration
208753_s_at	-0.893	8.160	-5.016	1.474e-04	0.042	1.178	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	BC002387	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
1555522_s_at	-0.844	7.572	-5.010	1.489e-04	0.042	1.168	MEMO1	mediator of cell motility 1	2	-31946398, -31946397	BC036262	51072	2p22-p21	Hs.444969	10	nucleus cytosol
1558924_s_at	-1.805	6.486	-5.008	1.495e-04	0.042	1.165	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	BF673049	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
230904_at	-1.395	5.557	-5.006	1.501e-04	0.042	1.161	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	W42665	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
205335_s_at	-0.528	8.585	-5.002	1.513e-04	0.042	1.154	SRP19	signal recognition particle 19kDa	5	112224891	NM_003135	6728	5q21-q22	Hs.637001	14	nucleolus cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane 7S RNA binding response to drug	Protein export
211928_at	-0.648	8.973	-5.002	1.513e-04	0.042	1.154	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	14	101500617	AB002323	1778	14q32 14q32.3-qter	Hs.649497	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm Golgi apparatus cytoplasmic dynein complex microtubule microtubule-based movement mitotic spindle organization ATPase activity, coupled
203066_at	-1.971	6.357	-4.999	1.521e-04	0.042	1.149	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	10	-125757173	NM_014863	51363	10q26	Hs.287537	12	Golgi apparatus membrane integral to membrane transferase activity hexose biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate binding N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	Chondroitin sulfate biosynthesis
212510_at	0.733	10.561	4.997	1.528e-04	0.042	1.145	GPD1L	glycerol-3-phosphate dehydrogenase 1-like	3	32123147	AA135522	23171	3p22.3	Hs.82432	5	glycerol-3-phosphate dehydrogenase (NAD+) activity binding cytoplasm carbohydrate metabolic process glycerol-3-phosphate dehydrogenase complex protein homodimerization activity glycerol-3-phosphate catabolic process NAD or NADH binding oxidation reduction	Glycerophospholipid metabolism
204560_at	-1.330	4.975	-4.993	1.539e-04	0.042	1.139	FKBP5	FK506 binding protein 5	6	-35656311, -35649339, -35649339, -35649339	NM_004117	2289	6p21.3-p21.2	Hs.407190	50	peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding
225329_at	0.508	6.748	4.988	1.554e-04	0.042	1.129	LOC348262	hypothetical protein LOC348262	17	-2338651	BF338291	348262	17q25.3	Hs.514632	1
222617_s_at	-1.002	7.394	-4.972	1.606e-04	0.043	1.100	C10orf84	chromosome 10 open reading frame 84	10	-120058561	AI147026	63877	10q26.11	Hs.372309	5
227923_at	0.872	7.008	4.966	1.622e-04	0.043	1.091	SHANK3	SH3 and multiple ankyrin repeat domains 3	22	49459935	BF439330	85358	22q13.3	Hs.149035	21	MAPKKK cascade embryonic epithelial tube formation protein binding cytoplasm plasma membrane postsynaptic density SH3 domain binding cell junction synapse postsynaptic membrane
228696_at	0.515	4.077	4.966	1.624e-04	0.043	1.090	SLC45A3	solute carrier family 45, member 3	1	-203893603	AA631143	85414	1q32.1	Hs.278695	9	transport membrane integral to membrane
243009_at	0.809	5.692	4.961	1.639e-04	0.043	1.081	LOC441242	hypothetical LOC441242	7		AW513654	441242	7q11.21	Hs.656146	2
202352_s_at	-0.615	8.329	-4.961	1.641e-04	0.043	1.080	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	17	-62767081, -62767080	AI446530	5718	17q24.2	Hs.646575	39	protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
63825_at	-1.053	6.770	-4.947	1.686e-04	0.044	1.055	ABHD2	abhydrolase domain containing 2	15	87432384	AI557319	11057	15q26.1	Hs.122337 Hs.705984	10	molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration
1555814_a_at	-0.925	9.327	-4.942	1.703e-04	0.044	1.046	RHOA	ras homolog gene family, member A	3	-49371582	AF498970	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
202942_at	0.983	9.610	4.939	1.711e-04	0.044	1.042	ETFB	electron-transfer-flavoprotein, beta polypeptide	19	-56540220, -56540220	NM_001985	2109	19q13.3	Hs.348531	16	mitochondrion mitochondrial matrix transport electron carrier activity electron transport chain
227025_at	-0.598	6.105	-4.938	1.715e-04	0.044	1.040	PPHLN1	periphilin 1	12	41006213, 41006213, 41006213, 41006213	BG284497	51535	12q12	Hs.444157	13	nucleus cytoplasm keratinization
207180_s_at	-0.631	7.429	-4.937	1.718e-04	0.044	1.038	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	NM_006410	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
205338_s_at	0.580	4.924	4.930	1.742e-04	0.044	1.026	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	NM_001922	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
225895_at	-1.319	9.185	-4.929	1.746e-04	0.044	1.023	SYNPO2	synaptopodin 2	4	120029443, 120029443	AI634580	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
228647_at	-0.944	6.202	-4.925	1.761e-04	0.044	1.016	LOC100049716	hypothetical protein LOC100049716	12		AI675844	100049716	12p13.33	Hs.655804	1
1554801_at	0.533	3.306	4.923	1.765e-04	0.044	1.014	C5orf40	chromosome 5 open reading frame 40	5	-156701184	BC022570	408263	5q33.3	Hs.437066	3	membrane integral to membrane
201132_at	-0.784	8.987	-4.923	1.766e-04	0.044	1.014	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	X	100549846	NM_019597	3188	Xq22	Hs.632828	17	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm cytoskeleton heterogeneous nuclear ribonucleoprotein complex
222423_at	-0.643	7.461	-4.920	1.775e-04	0.044	1.008	NDFIP1	Nedd4 family interacting protein 1	5	141468507	H05010	80762	5q31.3	Hs.653510 Hs.9788	11	signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport
213473_at	-0.629	6.935	-4.916	1.790e-04	0.044	1.001	BRAP	BRCA1 associated protein	12	-110564332	AL042733	8315	12q24	Hs.530940	12	ubiquitin-protein ligase activity cytoplasm zinc ion binding negative regulation of signal transduction ligase activity modification-dependent protein catabolic process identical protein binding metal ion binding
232184_at	-0.540	2.824	-4.911	1.810e-04	0.044	0.991	ALS2	amyotrophic lateral sclerosis 2 (juvenile)	2	-202332427, -202273231	AK023024	57679	2q33.1	Hs.471096 Hs.621812	36	ruffle guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity protein binding intracellular early endosome centrosome cytosol endosome organization cell death Rab guanyl-nucleotide exchange factor activity Rab GTPase binding Rab GTPase binding lamellipodium dendrite Rac guanyl-nucleotide exchange factor activity positive regulation of Rac GTPase activity positive regulation of Rac protein signal transduction regulation of Rho protein signal transduction vesicular fraction protein homodimerization activity protein complex protein serine/threonine kinase activator activity positive regulation of protein kinase activity neuron projection morphogenesis regulation of endosome size	Amyotrophic lateral sclerosis (ALS)
200915_x_at	-0.702	11.862	-4.909	1.816e-04	0.044	0.988	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	NM_004986	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
1552701_a_at	0.935	4.232	4.907	1.821e-04	0.044	0.985	CARD16	caspase recruitment domain family, member 16	11	-104417262	NM_052889	114769		Hs.348365	8	cysteine-type endopeptidase activity cysteine-type endopeptidase inhibitor activity protein binding intracellular proteolysis peptidase inhibitor activity regulation of apoptosis
201397_at	0.510	6.069	4.904	1.835e-04	0.044	0.979	PHGDH	phosphoglycerate dehydrogenase	1	120055941	NM_006623	26227	1p12	Hs.487296	18	phosphoglycerate dehydrogenase activity L-serine biosynthetic process brain development cellular amino acid biosynthetic process electron carrier activity oxidoreductase activity cofactor binding NAD or NADH binding oxidation reduction	Glycine, serine and threonine metabolism Metabolic pathways
203933_at	-0.615	6.466	-4.900	1.848e-04	0.044	0.972	RAB11FIP3	RAB11 family interacting protein 3 (class II)	16	415668, 464850	NM_014700	9727	16p13.3	Hs.531642	18	calcium ion binding protein binding protein transport membrane Rab GTPase binding recycling endosome	Endocytosis
222572_at	1.464	9.672	4.900	1.848e-04	0.044	0.972	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	8	94998258, 94998337, 94998350, 94998454, 94999167	BG542521	54704	8q22.1	Hs.22265	19	magnesium ion binding protein serine/threonine phosphatase activity [pyruvate dehydrogenase (lipoamide)] phosphatase activity calcium ion binding mitochondrion mitochondrial matrix protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity
224856_at	-1.999	8.312	-4.899	1.852e-04	0.044	0.970	FKBP5	FK506 binding protein 5	6	-35656311, -35649339, -35649339, -35649339	W86302	2289	6p21.3-p21.2	Hs.407190	50	peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding
210445_at	0.529	4.524	4.898	1.855e-04	0.044	0.968	FABP6	fatty acid binding protein 6, ileal	5	159546951, 159558625, 159589014	U19869	2172	5q33.3-q34	Hs.519719	18	transporter activity fatty acid binding cytoplasm cytosol lipid metabolic process transport steroid metabolic process negative regulation of cell proliferation	PPAR signaling pathway
222437_s_at	-0.698	9.163	-4.897	1.860e-04	0.044	0.966	VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	2	-86584063	BC004419	51652	2p24.3-p24.1	Hs.591582	25	protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division	Endocytosis
202179_at	-0.537	6.492	-4.887	1.895e-04	0.044	0.949	BLMH	bleomycin hydrolase	17	-25599348	NM_000386	642	17q11.2	Hs.371914	27	aminopeptidase activity carboxypeptidase activity cysteine-type endopeptidase activity soluble fraction nucleus cytoplasm proteolysis peptidase activity response to toxin response to drug
221497_x_at	-1.033	7.147	-4.884	1.908e-04	0.044	0.943	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	BC005369	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
235521_at	0.826	6.453	4.878	1.931e-04	0.045	0.932	HOXA3	homeobox A3	7	-27112333, -27112333, -27112333	AW137982	3200	7p15-p14	Hs.659337	18	blood vessel remodeling transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation specification of organ position glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding thymus development organ formation embryonic skeletal system morphogenesis cartilage development parathyroid gland development
217995_at	-0.861	9.138	-4.877	1.935e-04	0.045	0.930	SQRDL	sulfide quinone reductase-like (yeast)	15	43714547	NM_021199	58472	15q15	Hs.511251	6	mitochondrion mitochondrial inner membrane oxidoreductase activity oxidation reduction
213645_at	-1.712	6.686	-4.874	1.945e-04	0.045	0.925	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	AF305057	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
209406_at	-0.758	8.221	-4.870	1.962e-04	0.045	0.917	BAG2	BCL2-associated athanogene 2	6	57145062	AF095192	9532	6p12.1-p11.2	Hs.719303	16	protein binding protein folding apoptosis protein metabolic process
208754_s_at	-0.983	7.540	-4.856	2.016e-04	0.046	0.893	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AL162068	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
208456_s_at	-0.974	6.926	-4.850	2.038e-04	0.046	0.883	RRAS2	related RAS viral (r-ras) oncogene homolog 2	11	-14256041, -14256041	NM_012250	22800	11p15.2	Hs.502004	25	nucleotide binding GTPase activity protein binding GTP binding intracellular endoplasmic reticulum plasma membrane Ras protein signal transduction cellular process positive regulation of cell migration	MAPK signaling pathway Tight junction Regulation of actin cytoskeleton
227718_at	-1.204	6.497	-4.848	2.047e-04	0.046	0.879	PURB	purine-rich element binding protein B	7	-44882416	BF337790	5814	7p13	Hs.349150 Hs.596321	13	translation repressor activity, nucleic acid binding double-stranded DNA binding single-stranded DNA binding transcription factor activity mRNA binding nucleus DNA replication factor A complex transcription factor binding specific transcriptional repressor activity purine-rich negative regulatory element binding regulation of transcription regulation of myeloid cell differentiation negative regulation of transcription, DNA-dependent SMAD binding
224758_at	-0.639	4.495	-4.848	2.049e-04	0.046	0.878	PL-5283	PL-5283 protein	7	134997760	BG393032	647087	7q33	Hs.200022	3
225043_at	-1.009	7.196	-4.847	2.050e-04	0.046	0.878	SLC15A4	solute carrier family 15, member 4	12	-127843692	AW304786	121260	12q24.32-q24.33	Hs.507260 Hs.699387	6	transporter activity oligopeptide transport protein transport symporter activity membrane integral to membrane
202322_s_at	-0.645	8.013	-4.842	2.074e-04	0.046	0.867	GGPS1	geranylgeranyl diphosphate synthase 1	1	233558375, 233558491	NM_004837	9453	1q43	Hs.719270	13	dimethylallyltranstransferase activity farnesyltranstransferase activity geranyltranstransferase activity soluble fraction cytoplasm isoprenoid biosynthetic process transferase activity	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
231779_at	-1.006	6.289	-4.839	2.083e-04	0.046	0.863	IRAK2	interleukin-1 receptor-associated kinase 2	3	10181562	AI246590	3656	3p25.3	Hs.449207	15	regulation of cytokine-mediated signaling pathway MyD88-dependent toll-like receptor signaling pathway protein kinase activity NF-kappaB-inducing kinase activity ATP binding protein amino acid phosphorylation inflammatory response signal transduction I-kappaB kinase/NF-kappaB cascade cell surface lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity protein homodimerization activity protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway response to interleukin-1	Apoptosis Neurotrophin signaling pathway
202646_s_at	-0.661	11.463	-4.838	2.088e-04	0.046	0.861	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	AA167775	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
212219_at	-0.572	8.217	-4.836	2.096e-04	0.046	0.857	PSME4	proteasome (prosome, macropain) activator subunit 4	2	-53944707	D38521	23198	2p16.2	Hs.413801	30	binding nucleus cytosol multicellular organismal development spermatogenesis nuclear speck cell differentiation protein complex	Proteasome
226206_at	-0.873	8.209	-4.831	2.116e-04	0.046	0.848	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	7	1536893	BG231691	7975	7p22.3	Hs.520612	14	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent nervous system development sequence-specific DNA binding
218177_at	-0.978	5.945	-4.822	2.156e-04	0.047	0.831	CHMP1B	chromatin modifying protein 1B	18	11841388	AA293502	57132	18p11.21	Hs.656244	16	cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division	Endocytosis
242029_at	-0.612	6.163	-4.820	2.164e-04	0.047	0.828	FNDC3B	fibronectin type III domain containing 3B	3	173240111, 173241037	N32832	64778	3q26.31	Hs.159430	9	endoplasmic reticulum membrane integral to membrane
212845_at	-0.813	10.495	-4.817	2.177e-04	0.047	0.823	SAMD4A	sterile alpha motif domain containing 4A	14	54104386, 54291255	AB028976	23034	14q22.2	Hs.98259	4	cytoplasm synaptosome translation repressor activity dendrite positive regulation of translation
222628_s_at	0.567	7.225	4.816	2.182e-04	0.047	0.821	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	AA195405	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
219631_at	-0.875	5.780	-4.815	2.184e-04	0.047	0.820	LRP12	low density lipoprotein-related protein 12	8	-105570642	NM_024937	29967	8q22.2-q23.1	Hs.600630	8	receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth
206799_at	2.245	5.452	4.814	2.192e-04	0.047	0.816	SCGB1D2	secretoglobin, family 1D, member 2	11	61766299	NM_006551	10647	11q13	Hs.204096	9	binding extracellular region extracellular space
222989_s_at	-0.801	7.341	-4.812	2.199e-04	0.047	0.813	UBQLN1	ubiquilin 1	9	-85464697	NM_013438	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
209281_s_at	-0.918	6.140	-4.811	2.205e-04	0.047	0.811	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	12	-88505956	M95541	490	12q21.3	Hs.506276	38	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
240259_at	-1.509	5.668	-4.808	2.217e-04	0.047	0.806	FLRT2	fibronectin leucine rich transmembrane protein 2	14	85066240	AI188161	23768	14q24-q32	Hs.533710 Hs.624735 Hs.719261	9	receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging
225007_at	-0.705	7.564	-4.803	2.240e-04	0.047	0.797	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	AV705516	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
203544_s_at	-0.769	7.175	-4.798	2.259e-04	0.047	0.789	STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	10	17726129	NM_003473	8027	10p14-p13	Hs.441498	30	SH3/SH2 adaptor activity protein binding cytoplasm endosome cytosol intracellular protein transport signal transduction membrane	Endocytosis Jak-STAT signaling pathway
210211_s_at	-0.738	11.097	-4.798	2.262e-04	0.047	0.788	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	AF028832	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
212878_s_at	-0.839	7.919	-4.796	2.267e-04	0.047	0.786	KLC1	kinesin light chain 1	14	103165277, 103165277	AA284075	3831	14q32.3	Hs.20107 Hs.657678	31	microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle
206238_s_at	-0.820	6.316	-4.794	2.280e-04	0.047	0.780	YAF2	YY1 associated factor 2	12	-40837173	NM_005748	10138	12q12	Hs.708084	9	transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus zinc ion binding negative regulation of transcription positive regulation of transcription metal ion binding
1555363_s_at	0.476	5.734	4.788	2.306e-04	0.047	0.770	LOC284440	hypothetical LOC284440	19	-19728182	BC034236	284440	19p13.11	Hs.665307	4
238877_at	-0.920	8.373	-4.787	2.308e-04	0.047	0.769	EYA4	eyes absent homolog 4 (Drosophila)	6	133604187	BE674583	2070	6q23	Hs.596680	15	magnesium ion binding protein tyrosine phosphatase activity nucleus cytoplasm DNA repair response to DNA damage stimulus multicellular organismal development visual perception metabolic process anatomical structure morphogenesis chromatin modification hydrolase activity regulation of transcription
212589_at	-0.780	8.264	-4.786	2.314e-04	0.047	0.767	RRAS2	related RAS viral (r-ras) oncogene homolog 2	11	-14256041, -14256041	AI753792	22800	11p15.2	Hs.502004	25	nucleotide binding GTPase activity protein binding GTP binding intracellular endoplasmic reticulum plasma membrane Ras protein signal transduction cellular process positive regulation of cell migration	MAPK signaling pathway Tight junction Regulation of actin cytoskeleton
232173_at	0.673	5.724	4.780	2.343e-04	0.048	0.756	CLEC2L	C-type lectin domain family 2, member L	7	138859213	W60866	154790	7q34	Hs.57806	3	binding sugar binding membrane integral to membrane
203909_at	-0.796	6.966	-4.767	2.402e-04	0.049	0.733	SLC9A6	solute carrier family 9 (sodium/hydrogen exchanger), member 6	X	134895251	NM_006359	10479	Xq26.3	Hs.62185	11	mitochondrion endosome endoplasmic reticulum membrane microsome plasma membrane cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity integral to membrane sodium ion binding early endosome membrane recycling endosome membrane	Cardiac muscle contraction
212993_at	-0.695	7.263	-4.760	2.437e-04	0.049	0.720	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	9	-138043023	AA114166	138151	9q34.3	Hs.112895	3	protein binding nucleus positive regulation of cell proliferation negative regulation of transcription specific transcriptional repressor activity nuclear body protein homooligomerization
200835_s_at	-0.948	8.763	-4.759	2.441e-04	0.049	0.718	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AI553791	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
225010_at	-0.733	7.666	-4.752	2.477e-04	0.049	0.705	CCDC6	coiled-coil domain containing 6	10	-61218526	AK024913	8030	10q21	Hs.591360	20	structural constituent of cytoskeleton protein binding cellular_component cytoplasm cytoskeleton biological_process SH3 domain binding	Pathways in cancer Thyroid cancer
201106_at	-0.678	10.229	-4.743	2.522e-04	0.050	0.688	GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)	19	1054935, 1055648	NM_002085	2879	19p13.3	Hs.433951	50	glutathione peroxidase activity soluble fraction nucleus nuclear envelope cytoplasm mitochondrion mitochondrial inner membrane cytosol chromatin organization phospholipid metabolic process glutathione metabolic process response to oxidative stress multicellular organismal development spermatogenesis selenium binding oxidoreductase activity hydrogen peroxide catabolic process glutathione binding phospholipid-hydroperoxide glutathione peroxidase activity regulation of inflammatory response oxidation reduction	Glutathione metabolism Arachidonic acid metabolism
202779_s_at	-1.371	5.832	-4.739	2.539e-04	0.050	0.682	UBE2S	ubiquitin-conjugating enzyme E2S	19	-60604461	NM_014501	27338	19q13.43	Hs.396393	6	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
1558675_s_at	-0.814	6.888	-4.735	2.558e-04	0.050	0.675	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	AV724508	9147	14q22	Hs.655964	8	nucleus cytoplasm
236192_at	-0.571	5.637	-4.735	2.559e-04	0.050	0.675	HOOK3	hook homolog 3 (Drosophila)	8	42871189	BF447112	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
202055_at	-0.912	8.509	-4.735	2.562e-04	0.050	0.674	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	AA652173	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
204143_s_at	-1.636	6.074	-4.732	2.576e-04	0.050	0.669	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	NM_017512	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
200994_at	-0.477	10.164	-4.731	2.583e-04	0.050	0.667	IPO7	importin 7	11	9362744	BG291787	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
209439_s_at	0.673	6.957	4.729	2.594e-04	0.050	0.663	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	D38616	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
219629_at	0.730	5.097	4.728	2.595e-04	0.050	0.662	FAM118A	family with sequence similarity 118, member A	22	44083744, 44084448	NM_017911	55007	22q13	Hs.265018	6	membrane integral to membrane
225521_at	-0.926	5.871	-4.728	2.596e-04	0.050	0.662	ANAPC7	anaphase promoting complex subunit 7	12	-109297656, -109295087	AL137586	51434	12q24.11	Hs.524741	30	binding nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
222656_at	-1.266	6.165	-4.723	2.625e-04	0.050	0.652	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	8	-74865393	AI625741	55284	8q21.11	Hs.597486	7	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
205903_s_at	-0.666	4.868	-4.721	2.632e-04	0.050	0.650	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1	-152946536, -152946536	NM_002249	3782	1q21.3	Hs.490765	40	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
204186_s_at	-0.990	7.957	-4.715	2.667e-04	0.050	0.637	PPID	peptidylprolyl isomerase D	4	-159849728	AI014573	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
60471_at	0.613	5.612	4.713	2.673e-04	0.050	0.635	RIN3	Ras and Rab interactor 3	14	92049877	AA625133	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
211672_s_at	-0.884	6.332	-4.708	2.702e-04	0.051	0.625	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	3	9809226	AF019888	10093	3p25.3	Hs.323342	16	cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
221752_at	-0.803	6.388	-4.705	2.716e-04	0.051	0.621	SSH1	slingshot homolog 1 (Drosophila)	12	-107709824, -107709824, -107700595	AL041728	54434	12q24.11	Hs.199763	23	cell morphogenesis actin binding protein tyrosine phosphatase activity protein binding cytoplasm cytoskeleton plasma membrane protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity lamellipodium actin cytoskeleton organization	Regulation of actin cytoskeleton
219939_s_at	-0.543	12.053	-4.696	2.768e-04	0.052	0.603	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	NM_007158	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
200059_s_at	-0.735	10.457	-4.691	2.796e-04	0.052	0.594	RHOA	ras homolog gene family, member A	3	-49371582	BC001360	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
235549_at	-1.322	4.321	-4.690	2.798e-04	0.052	0.594	RNF144B	ring finger protein 144B	6	18495572	AL575512	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
203836_s_at	0.996	6.368	4.687	2.819e-04	0.052	0.587	MAP3K5	mitogen-activated protein kinase kinase kinase 5	6	-136919879	D84476	4217	6q22.33	Hs.186486	108	MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding protein amino acid phosphorylation apoptosis activation of JUN kinase activity induction of apoptosis by extracellular signals caspase activator activity transferase activity protein homodimerization activity interspecies interaction between organisms	MAPK signaling pathway Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS)
201681_s_at	-1.145	7.124	-4.685	2.828e-04	0.052	0.584	DLG5	discs, large homolog 5 (Drosophila)	10	-79220554	AB011155	9231	10q23	Hs.652690	49	protein binding intracellular cytoplasm plasma membrane cell-cell adherens junction intracellular signaling cascade negative regulation of cell proliferation cell-cell adhesion cell junction receptor signaling complex scaffold activity regulation of apoptosis
205417_s_at	-0.560	9.122	-4.681	2.850e-04	0.052	0.577	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	3	49482568	NM_004393	1605	3p21	Hs.707131 Hs.76111	56	morphogenesis of an epithelial sheet calcium ion binding protein binding extracellular region basement membrane extracellular space membrane fraction cytoplasm integral to plasma membrane protein complex assembly muscle contraction actin cytoskeleton dystroglycan complex sarcolemma membrane raft	ECM-receptor interaction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
204400_at	0.686	4.839	4.681	2.852e-04	0.052	0.576	EFS	embryonal Fyn-associated substrate	14	-22895450	NM_005864	10278	14q11.2-q12	Hs.24587	8	cytoplasm cell adhesion intracellular signaling cascade SH3 domain binding
225665_at	-0.722	11.862	-4.678	2.869e-04	0.052	0.571	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AI129320	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
208752_x_at	-0.816	9.727	-4.678	2.870e-04	0.052	0.570	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AI888672	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
226879_at	0.482	6.393	4.676	2.880e-04	0.052	0.567	HVCN1	hydrogen voltage-gated channel 1	12	-109570873, -109570873	AW406569	84329	12q24.11	Hs.211511 Hs.334637	11	voltage-gated ion channel activity ion transport response to pH response to zinc ion response to zinc ion proton transport membrane integral to membrane voltage-gated proton channel activity voltage-gated proton channel activity
223041_at	-0.776	7.409	-4.674	2.893e-04	0.052	0.563	CD99L2	CD99 molecule-like 2	X	-149685466	AL136580	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
220610_s_at	-0.903	6.899	-4.665	2.942e-04	0.052	0.548	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	NM_006309	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
228450_at	0.776	3.691	4.658	2.984e-04	0.052	0.535	PLEKHA7	pleckstrin homology domain containing, family A member 7	11	-16765787	AA758861	144100	11p15.1	Hs.12332	4	protein binding
242323_at	0.769	8.505	4.657	2.991e-04	0.052	0.533	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AV714268	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
209212_s_at	-1.317	6.219	-4.656	2.997e-04	0.052	0.531	KLF5	Kruppel-like factor 5 (intestinal)	13	72531142	AB030824	688	13q22.1	Hs.508234	50	angiogenesis transcription factor activity RNA polymerase II transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter zinc ion binding positive regulation of cell proliferation microvillus assembly positive regulation of transcription metal ion binding
214461_at	-2.842	4.182	-4.656	2.998e-04	0.052	0.530	LBP	lipopolysaccharide binding protein	20	36408298	NM_004139	3929	20q11.23-q12	Hs.154078	58	lipopolysaccharide binding macrophage activation during immune response receptor binding extracellular region extracellular region extracellular space extracellular space nucleus lipid transport acute-phase response acute-phase response cellular defense response opsonization opsonization lipid binding lipopolysaccharide transport lipopolysaccharide-mediated signaling pathway detection of molecule of bacterial origin response to lipopolysaccharide negative regulation of tumor necrosis factor production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 4 signaling pathway positive regulation of macrophage activation cell surface binding innate immune response innate immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium Gram-negative bacterial cell surface binding Gram-negative bacterial cell surface binding Gram-positive bacterial cell surface binding positive regulation of respiratory burst during acute inflammatory response	Toll-like receptor signaling pathway
223652_at	1.266	6.104	4.655	3.001e-04	0.052	0.530	AS3MT	arsenic (+3 oxidation state) methyltransferase	10	104619199	AF226730	57412	10q24.32	Hs.34492	24	soluble fraction cytoplasm cytosol metabolic process methyltransferase activity toxin metabolic process transferase activity arsonoacetate metabolic process arsenite methyltransferase activity methylarsonite methyltransferase activity response to arsenic
223125_s_at	-0.743	9.410	-4.654	3.008e-04	0.052	0.528	C1orf21	chromosome 1 open reading frame 21	1	182622772	AL563236	81563	1q25	Hs.497159 Hs.719188	8
206703_at	-1.066	6.822	-4.650	3.034e-04	0.053	0.520	CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)	17	7289129	NM_000747	1140	17p13.1	Hs.330386	20	postsynaptic membrane organization nicotinic acetylcholine-activated cation-selective channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex cation transport muscle contraction signal transduction synaptic transmission, cholinergic neuromuscular synaptic transmission channel activity acetylcholine receptor activity cell junction behavioral response to nicotine regulation of membrane potential synapse postsynaptic membrane muscle fiber development neurological system process
242915_at	1.380	3.739	4.646	3.058e-04	0.053	0.512	ZNF682	zinc finger protein 682	19	-19976226, -19976226	AA603590	91120	19p12	Hs.306298	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224435_at	0.875	8.214	4.641	3.089e-04	0.053	0.503	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	BC005871	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
235049_at	0.771	5.891	4.640	3.092e-04	0.053	0.502	ADCY1	adenylate cyclase 1 (brain)	7	45580649	AA021120	107	7p13-p12	Hs.192215	24	nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis
1557950_at	-0.770	6.619	-4.639	3.097e-04	0.053	0.501	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	BF984340	9147	14q22	Hs.655964	8	nucleus cytoplasm
224314_s_at	-0.996	5.655	-4.626	3.184e-04	0.054	0.475	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	AF277174	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
223681_s_at	-1.634	8.420	-4.624	3.191e-04	0.054	0.473	INADL	InaD-like (Drosophila)	1	61980736	AB044807	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
224743_at	-0.934	8.892	-4.621	3.211e-04	0.054	0.468	IMPAD1	inositol monophosphatase domain containing 1	8	-58033041	BF674724	54928	8q12.1	Hs.716471	4	magnesium ion binding inositol-1(or 4)-monophosphatase activity membrane integral to membrane hydrolase activity
221495_s_at	-0.563	7.674	-4.620	3.219e-04	0.054	0.465	TCF25	transcription factor 25 (basic helix-loop-helix)	16	88467494	AF322111	22980	16q24.3	Hs.415342	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus heart development regulation of transcription
230329_s_at	0.886	7.493	4.619	3.223e-04	0.054	0.464	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	4	-124033248, -124033248	AI580268	11162	4q26	Hs.558459	15	cellular_component growth factor activity biological_process hydrolase activity
225379_at	-0.672	8.104	-4.617	3.241e-04	0.054	0.459	MAPT	microtubule-associated protein tau	17	41327543	AA199717	4137	17q21.1	Hs.101174	545	microtubule cytoskeleton organization microtubule cytoskeleton organization structural constituent of cytoskeleton cytoplasm cytosol cytoskeleton microtubule microtubule associated complex plasma membrane plasma membrane negative regulation of microtubule depolymerization microtubule binding microtubule binding lipoprotein binding SH3 domain binding enzyme binding axon axon growth cone growth cone positive regulation of microtubule polymerization positive regulation of microtubule polymerization apolipoprotein E binding identical protein binding cell projection tubulin complex tubulin complex positive regulation of axon extension positive regulation of axon extension generation of neurons	MAPK signaling pathway Alzheimer's disease
203269_at	-0.491	8.020	-4.616	3.247e-04	0.054	0.457	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	8	-59658619, -59658619	NM_003580	8439	8q12-q13	Hs.372000	8	receptor signaling protein activity soluble fraction cytoplasm ceramide metabolic process signal transduction
203360_s_at	-1.007	6.026	-4.602	3.340e-04	0.055	0.432	MYCBP	c-myc binding protein	1	-39101222	D50692	26292	1p33-p32.2	Hs.591506	12	transcription coactivator activity protein binding nucleus cytoplasm mitochondrion spermatogenesis regulation of transcription
33850_at	-0.623	8.659	-4.601	3.347e-04	0.055	0.430	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	W28892	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
203913_s_at	-0.697	2.683	-4.595	3.388e-04	0.056	0.419	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	4	-175647902, -175647902	AL574184	3248	4q34-q35	Hs.596913	47	prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction
222258_s_at	-1.211	5.744	-4.591	3.415e-04	0.056	0.411	SH3BP4	SH3-domain binding protein 4	2	235525366	AF015043	23677	2q37.1-q37.2	Hs.516777	12	molecular_function signal transducer activity protein binding cellular_component nucleus coated pit endocytosis cell cycle biological_process membrane clathrin-coated vesicle cytoplasmic vesicle
219464_at	1.331	7.403	4.589	3.425e-04	0.056	0.409	CA14	carbonic anhydrase XIV	1	148496841	NM_012113	23632	1q21	Hs.528988	11	carbonate dehydratase activity zinc ion binding membrane integral to membrane lyase activity metal ion binding	Nitrogen metabolism
212470_at	-0.717	8.166	-4.585	3.454e-04	0.056	0.401	SPAG9	sperm associated antigen 9	17	-46394534	AB011088	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
214152_at	-0.696	7.299	-4.584	3.461e-04	0.056	0.399	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AU144243	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
226065_at	0.769	6.761	4.584	3.461e-04	0.056	0.399	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	N98595	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
221838_at	0.502	4.960	4.583	3.465e-04	0.056	0.398	KLHL22	kelch-like 22 (Drosophila)	22	-19125805	N38751	84861	22q11.21	Hs.517419	6	protein binding
229310_at	-1.435	5.992	-4.581	3.483e-04	0.056	0.393	KLHL29	kelch-like 29 (Drosophila)	2		BE465475	114818	2p24.1	Hs.130593	5	protein binding
202381_at	-0.731	7.704	-4.579	3.494e-04	0.056	0.390	ADAM9	ADAM metallopeptidase domain 9 (meltrin gamma)	8	38973661, 38973661	NM_003816	8754	8p11.22	Hs.591852	36	activation of MAPKK activity metalloendopeptidase activity protein kinase C binding integrin binding integrin binding integrin binding collagen binding extracellular region extracellular space cytoplasm plasma membrane proteolysis response to oxidative stress cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway peptidase activity zinc ion binding cell surface response to manganese ion integral to membrane SH3 domain binding SH3 domain binding keratinocyte differentiation intrinsic to external side of plasma membrane positive regulation of cell adhesion mediated by integrin cell-cell adhesion mediated by integrin positive regulation of macrophage fusion response to tumor necrosis factor monocyte activation response to hydrogen peroxide laminin binding metal ion binding positive regulation of protein secretion positive regulation of membrane protein ectodomain proteolysis PMA-inducible membrane protein ectodomain proteolysis response to glucocorticoid stimulus positive regulation of keratinocyte migration response to calcium ion
213245_at	0.973	5.967	4.578	3.502e-04	0.056	0.388	ADCY1	adenylate cyclase 1 (brain)	7	45580649	AL120173	107	7p13-p12	Hs.192215	24	nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis
208840_s_at	-1.236	6.285	-4.578	3.503e-04	0.056	0.388	G3BP2	GTPase activating protein (SH3 domain) binding protein 2	4	-76786976, -76786976	AU149503	9908	4q21.1	Hs.303676	15	nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport
208029_s_at	-1.441	8.976	-4.577	3.510e-04	0.056	0.386	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	NM_018407	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
222736_s_at	-0.925	6.886	-4.575	3.525e-04	0.056	0.382	TMEM38B	transmembrane protein 38B	9	107496645	BC000049	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
228702_at	-1.450	7.814	-4.570	3.557e-04	0.056	0.374	FLJ43663	hypothetical LOC378805	7	-130279458, -130279458	AL569506	378805	7q32.3	Hs.150556 Hs.649308	2
219024_at	-0.994	6.599	-4.569	3.562e-04	0.056	0.373	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	10	124124209, 124141832	NM_021622	59338	10q26.13	Hs.643512	16	phospholipid binding cellular_component nucleus cytoplasm plasma membrane biological_process
214151_s_at	-0.736	7.368	-4.567	3.581e-04	0.056	0.368	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AU144243	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
238841_at	0.627	5.301	4.566	3.583e-04	0.056	0.367	PTPDC1	protein tyrosine phosphatase domain containing 1	9	95832896, 95886566	AA651920	138639	9q22.32	Hs.437943	2	protein tyrosine phosphatase activity protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
200830_at	-0.520	9.581	-4.566	3.588e-04	0.056	0.366	PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	3	185499715	NM_002808	5708	3q27.1	Hs.518464	45	proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
231773_at	-1.329	7.221	-4.565	3.594e-04	0.056	0.365	ANGPTL1	angiopoietin-like 1	1	-177085292	BF002046	9068	1q25.2	Hs.591474	19	receptor binding extracellular region extracellular space signal transduction
235653_s_at	-1.096	5.193	-4.561	3.620e-04	0.056	0.358	THAP6	THAP domain containing 6	4	76658677	BF685315	152815	4q21.1	Hs.479971	10	DNA binding zinc ion binding microtubule cytoskeleton metal ion binding
203282_at	-0.836	10.895	-4.559	3.638e-04	0.056	0.353	GBE1	glucan (1,4-alpha-), branching enzyme 1	3	-81621539	NM_000158	2632	3p12.3	Hs.436062	20	1,4-alpha-glucan branching enzyme activity 1,4-alpha-glucan branching enzyme activity hydrolase activity, hydrolyzing O-glycosyl compounds cytosol carbohydrate metabolic process glycogen biosynthetic process generation of precursor metabolites and energy transferase activity, transferring glycosyl groups cation binding	Starch and sucrose metabolism Metabolic pathways
202753_at	-0.440	9.889	-4.554	3.673e-04	0.056	0.345	PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	3	-63971270	NM_014814	9861	3p14.1	Hs.152536	35	proteasome complex protein binding cytosol proteolysis ATPase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
225398_at	-0.977	9.382	-4.552	3.686e-04	0.056	0.342	RPUSD4	RNA pseudouridylate synthase domain containing 4	11	-125577199	AL580514	84881	11q24.2	Hs.150458	5	pseudouridine synthesis RNA binding pseudouridine synthase activity
203405_at	-0.822	6.521	-4.551	3.693e-04	0.056	0.340	PSMG1	proteasome (prosome, macropain) assembly chaperone 1	21	-39469253	NM_003720	8624	21q22.3	Hs.473838	12	protein binding cytoplasm endoplasmic reticulum proteasome assembly
220235_s_at	-1.162	6.973	-4.550	3.702e-04	0.056	0.338	C1orf103	chromosome 1 open reading frame 103	1	-111291334	NM_018372	55791	1p13.3	Hs.25245	7	protein binding
204204_at	-0.980	6.238	-4.550	3.703e-04	0.056	0.337	SLC31A2	solute carrier family 31 (copper transporters), member 2	9	114953058	NM_001860	1318	9q31-q32	Hs.24030	7	copper ion transmembrane transporter activity copper ion binding integral to plasma membrane ion transport copper ion transport membrane
212248_at	-0.637	8.201	-4.539	3.788e-04	0.058	0.316	MTDH	metadherin	8	98725582	AI886796	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
218534_s_at	-0.844	6.554	-4.535	3.814e-04	0.058	0.310	AGGF1	angiogenic factor with G patch and FHA domains 1	5	76361987	NM_018046	55109	5q13.3	Hs.634849	12	vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm
217975_at	0.814	7.011	4.532	3.837e-04	0.058	0.305	WBP5	WW domain binding protein 5	X	102498035	NM_016303	51186	Xq22.2	Hs.533287	6	protein binding WW domain binding
205842_s_at	-1.224	5.011	-4.530	3.858e-04	0.058	0.300	JAK2	Janus kinase 2	9	4975244	AF001362	3717	9p24	Hs.656213	588	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding ATP binding nucleus cytoplasm cytoskeleton caveola apoptosis cell motion enzyme linked receptor protein signaling pathway tyrosine phosphorylation of STAT protein STAT protein nuclear translocation mesoderm development negative regulation of cell proliferation positive regulation of phosphoinositide 3-kinase cascade membrane transferase activity myeloid cell differentiation SH2 domain binding positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of DNA binding response to antibiotic positive regulation of peptidyl-tyrosine phosphorylation JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway	Chemokine signaling pathway Jak-STAT signaling pathway Adipocytokine signaling pathway
207551_s_at	-0.653	7.380	-4.528	3.868e-04	0.058	0.297	MSL3	male-specific lethal 3 homolog (Drosophila)	X	11686198, 11686198, 11687681	NM_006800	10943	Xp22.3	Hs.655288	6	chromatin chromatin binding transcription factor activity nucleus chromatin assembly or disassembly transcription from RNA polymerase II promoter multicellular organismal development chromatin modification regulation of transcription
210694_s_at	0.796	5.799	4.526	3.887e-04	0.058	0.293	MID1	midline 1 (Opitz/BBB syndrome)	X	-10373595, -10373595, -10373595	AF041209	4281	Xp22	Hs.27695	38	microtubule cytoskeleton organization protein binding intracellular cytoplasm microtubule microtubule associated complex negative regulation of microtubule depolymerization pattern specification process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
207001_x_at	-0.808	6.615	-4.517	3.954e-04	0.059	0.277	TSC22D3	TSC22 domain family, member 3	X	-106843107, -106843107, -106843107	NM_004089	1831	Xq22.3	Hs.716410	24	transcription factor activity regulation of transcription, DNA-dependent
203359_s_at	-0.964	6.336	-4.514	3.981e-04	0.059	0.271	MYCBP	c-myc binding protein	1	-39101222	AL525412	26292	1p33-p32.2	Hs.591506	12	transcription coactivator activity protein binding nucleus cytoplasm mitochondrion spermatogenesis regulation of transcription
212253_x_at	-0.563	7.883	-4.513	3.985e-04	0.059	0.270	DST	dystonin	6	-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743	BG253119	667	6p12.1	Hs.631992 Hs.669931	48	actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding
229287_at	-0.683	7.423	-4.512	3.995e-04	0.059	0.268	PCNX	pecanex homolog (Drosophila)	14	70443874	BE326214	22990	14q24.2	Hs.446559	10	membrane integral to membrane
203912_s_at	-0.729	9.011	-4.509	4.020e-04	0.059	0.262	DNASE1L1	deoxyribonuclease I-like 1	X	-153282772, -153282772	NM_006730	1774	Xq28	Hs.401929	14	DNA binding endonuclease activity deoxyribonuclease activity endoplasmic reticulum DNA catabolic process hydrolase activity
202500_at	-0.518	8.154	-4.504	4.065e-04	0.059	0.252	DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	2	219852283	NM_006736	3300	2q32-q34	Hs.77768	17	protein folding response to unfolded protein heat shock protein binding unfolded protein binding
243_g_at	-0.922	9.788	-4.503	4.067e-04	0.059	0.251	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	M64571	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
202003_s_at	0.949	10.017	4.503	4.073e-04	0.059	0.250	ACAA2	acetyl-Coenzyme A acyltransferase 2	18	-45563871	NM_006111	10449	18q21.1	Hs.200136	10	acetyl-CoA C-acyltransferase activity mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process cholesterol biosynthetic process metabolic process acyltransferase activity transferase activity	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Metabolic pathways
227198_at	2.701	4.681	4.503	4.074e-04	0.059	0.250	AFF3	AF4/FMR2 family, member 3	2	-99530147, -99530147	AW085505	3899	2q11.2-q12	Hs.444414	16	DNA binding nucleus multicellular organismal development regulation of transcription
203192_at	-0.757	6.466	-4.500	4.097e-04	0.059	0.245	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6	2	-219782737	NM_005689	10058	2q36	Hs.107911	15	nucleotide binding ATP binding mitochondrion mitochondrial envelope mitochondrial outer membrane transport cellular iron ion homeostasis membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters
209896_s_at	-1.779	6.546	-4.491	4.172e-04	0.060	0.228	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	AF119855	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
228863_at	0.891	4.329	4.491	4.172e-04	0.060	0.228	PCDH17	protocadherin 17	13	57103789	N69091	27253	13q21.1	Hs.106511	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
213789_at	0.472	5.459	4.488	4.193e-04	0.060	0.224	EBP	emopamil binding protein (sterol isomerase)	X	48265107	N58493	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
219926_at	-0.729	10.266	-4.487	4.200e-04	0.060	0.222	POPDC3	popeye domain containing 3	6	-105712475, -105712475	NM_022361	64208	6q21	Hs.458336	7	molecular_function biological_process membrane integral to membrane
239012_at	-1.494	7.441	-4.484	4.231e-04	0.061	0.215	RNF144B	ring finger protein 144B	6	18495572	R83905	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
212967_x_at	-0.681	9.824	-4.482	4.245e-04	0.061	0.212	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AW148801	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
222664_at	-0.609	5.271	-4.479	4.274e-04	0.061	0.206	KCTD15	potassium channel tetramerisation domain containing 15	19	38979590	AI808448	79047	19q13.11	Hs.221873 Hs.606506	12	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
200931_s_at	-0.907	10.478	-4.474	4.316e-04	0.061	0.197	VCL	vinculin	10	75427877	NM_014000	7414	10q22.2	Hs.643896	78	actin binding structural molecule activity cytoplasm plasma membrane cell-cell junction adherens junction focal adhesion cell motion cell adhesion actin cytoskeleton oxidoreductase activity lamellipodium assembly cell-substrate junction negative regulation of cell migration costamere protein complex apical junction assembly alpha-catenin binding	Focal adhesion Adherens junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
212742_at	-1.063	9.480	-4.470	4.353e-04	0.061	0.189	RNF115	ring finger protein 115	1	144322392	AL530462	27246	1q21.1	Hs.523550	8	protein binding zinc ion binding metal ion binding
212861_at	-0.591	6.426	-4.460	4.437e-04	0.062	0.172	MFSD5	major facilitator superfamily domain containing 5	12	51932146	BF690150	84975	12q13.13	Hs.654660	7	transport membrane integral to membrane
209605_at	0.961	8.090	4.455	4.483e-04	0.063	0.162	TST	thiosulfate sulfurtransferase (rhodanese)	22	-35736851	D87292	7263	22q13.1	Hs.474783	25	thiosulfate sulfurtransferase activity mitochondrion mitochondrial matrix plasma membrane sulfate transport cyanate catabolic process transferase activity
210788_s_at	-0.843	10.280	-4.453	4.505e-04	0.063	0.158	DHRS7	dehydrogenase/reductase (SDR family) member 7	14	-59681251	AF126782	51635	14q23.1	Hs.59719	7	binding oxidoreductase activity oxidation reduction
202760_s_at	1.597	6.045	4.451	4.519e-04	0.063	0.155	PALM2-AKAP2	PALM2-AKAP2 readthrough transcript	9	111582397, 111582409	NM_007203	445815	9q31-q33	Hs.591908	8
204219_s_at	-0.542	10.248	-4.450	4.532e-04	0.063	0.152	PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	14	89792646	NM_002802	5700	14q32.11	Hs.356654	51	nucleotide binding proteasome complex protein binding ATP binding nucleus nucleolus cytoplasm cytosol hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
210091_s_at	-0.671	7.854	-4.449	4.534e-04	0.063	0.152	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U46745	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
227792_at	-0.606	7.361	-4.448	4.544e-04	0.063	0.150	ITPRIPL2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	16	19032754	AA490685	162073	16p12.3	Hs.530899 Hs.648523	3	membrane integral to membrane
209345_s_at	-0.504	5.779	-4.446	4.560e-04	0.063	0.147	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha	10	99390432	AL561930	55361	10q24	Hs.25300	18	nucleotide binding magnesium ion binding 1-phosphatidylinositol 4-kinase activity protein binding ATP binding cytoplasm integral to plasma membrane phosphatidylinositol biosynthetic process membrane kinase activity transferase activity membrane raft
229377_at	-0.705	5.872	-4.441	4.611e-04	0.063	0.137	GRTP1	growth hormone regulated TBC protein 1	13	-113026505	BF001483	79774	13q34	Hs.170904	3	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
225419_at	-0.399	6.913	-4.440	4.620e-04	0.063	0.135	C7orf11	chromosome 7 open reading frame 11	7	-40138866	AI869704	136647	7p14.1	Hs.654989	9	nucleus
203244_at	-0.612	8.432	-4.438	4.637e-04	0.063	0.131	PEX5	peroxisomal biogenesis factor 5	12	7233025, 7233548, 7234224	NM_000319	5830	12p13.31	Hs.567327	45	protein binding cytoplasm peroxisome protein transport membrane
224818_at	-0.679	8.719	-4.432	4.692e-04	0.064	0.121	SORT1	sortilin 1	1	-109653714	BE622952	6272	1p21.3-p13.1	Hs.485195 Hs.703487	47	ossification receptor activity nucleus lysosome early endosome endoplasmic reticulum microsome Golgi apparatus plasma membrane coated pit transport Golgi to endosome transport endocytosis neuropeptide signaling pathway multicellular organismal development endosome to lysosome transport induction of apoptosis by extracellular signals cell surface nerve growth factor receptor activity regulation of gene expression myotube differentiation integral to membrane cytoplasmic membrane-bounded vesicle vesicle organization enzyme binding clathrin-coated vesicle cell differentiation neurotensin receptor activity, non-G-protein coupled endosome transport via multivesicular body sorting pathway response to insulin stimulus negative regulation of apoptosis glucose import nerve growth factor receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity	Lysosome Neurotrophin signaling pathway
212551_at	-0.725	11.501	-4.432	4.697e-04	0.064	0.120	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6	17501714	NM_006366	10486	6p22.3	Hs.132902	7	actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity
204311_at	0.531	5.735	4.429	4.726e-04	0.064	0.114	ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	17	7494978	NM_001678	482	17p13.1	Hs.712542	22	sodium:potassium-exchanging ATPase activity protein binding ATP biosynthetic process ion transport potassium ion transport sodium ion transport membrane integral to membrane potassium ion binding sodium ion binding	Cardiac muscle contraction
1552301_a_at	-0.856	10.094	-4.428	4.737e-04	0.064	0.112	CORO6	coronin 6	17	-24965899	NM_032854	84940	17q11.2	Hs.143046	7
206976_s_at	-1.110	8.022	-4.424	4.774e-04	0.064	0.105	HSPH1	heat shock 105kDa/110kDa protein 1	13	-30608762	NM_006644	10808	13q12.3	Hs.36927	25	nucleotide binding ATP binding cytoplasm response to unfolded protein
201662_s_at	-0.958	7.577	-4.424	4.775e-04	0.064	0.105	ACSL3	acyl-CoA synthetase long-chain family member 3	2	223433975	D89053	2181	2q34-q35	Hs.655772	20	nucleotide binding magnesium ion binding fatty-acyl-CoA synthase activity long-chain-fatty-acid-CoA ligase activity protein binding ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
203403_s_at	-1.034	8.283	-4.415	4.854e-04	0.064	0.089	RNF6	ring finger protein (C3H2C3 type) 6	13	-25684904, -25684904, -25684904	NM_005977	6049	13q12.2	Hs.136885	7	protein binding cellular_component biological_process zinc ion binding metal ion binding
209020_at	-0.700	7.971	-4.414	4.864e-04	0.064	0.088	C20orf111	chromosome 20 open reading frame 111	20	-42258549	AF217514	51526	20q13.11	Hs.75798	6
207076_s_at	1.793	7.831	4.414	4.873e-04	0.064	0.086	ASS1	argininosuccinate synthetase 1	9	132309914	NM_000050	445	9q34.1	Hs.160786	40	urea cycle nucleotide binding argininosuccinate synthase activity protein binding ATP binding cytoplasm arginine biosynthetic process cellular amino acid biosynthetic process ligase activity	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Metabolic pathways
212003_at	-0.485	6.891	-4.412	4.893e-04	0.064	0.082	C1orf144	chromosome 1 open reading frame 144	1	16566169	BG171020	26099	1p36.13	Hs.252967	2
209412_at	-0.717	6.010	-4.411	4.896e-04	0.064	0.082	TRAPPC10	trafficking protein particle complex 10	21	44256633	U61500	7109	21q22.3	Hs.126221	12	Golgi apparatus sodium ion transport sodium ion transmembrane transporter activity integral to membrane vesicle-mediated transport
230619_at	-0.472	6.369	-4.407	4.940e-04	0.065	0.073	ARNT	aryl hydrocarbon receptor nuclear translocator	1	-149048809	AI768497	405	1q21	Hs.632446	88	response to hypoxia positive regulation of endothelial cell proliferation RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus regulation of transcription, DNA-dependent signal transduction positive regulation vascular endothelial growth factor production aryl hydrocarbon receptor binding positive regulation of vascular endothelial growth factor receptor signaling pathway mRNA transcription from RNA polymerase II promoter positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of glycolysis positive regulation of hormone biosynthetic process protein heterodimerization activity	Pathways in cancer Renal cell carcinoma
222156_x_at	-0.838	6.792	-4.406	4.944e-04	0.065	0.073	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AK022459	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
1556134_a_at	-1.353	7.294	-4.405	4.961e-04	0.065	0.069	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	3	184453725	BC013229	84002	3q28	Hs.718506	7	intracellular Golgi apparatus protein amino acid glycosylation multicellular organismal development central nervous system development galactosyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity lipopolysaccharide N-acetylglucosaminyltransferase activity glycolipid biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
213353_at	-0.922	7.885	-4.403	4.974e-04	0.065	0.067	ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5	17	-64752170, -64752170	BF693921	23461	17q24.3	Hs.421474	11	nucleotide binding ATP binding lysosome endosome Golgi apparatus transport membrane integral to membrane ATPase activity	ABC transporters
1554600_s_at	-0.643	7.290	-4.403	4.979e-04	0.065	0.066	LMNA	lamin A/C	1	154351084, 154351084	BC033088	4000	1q21.2-q21.3	Hs.594444	279	structural molecule activity protein binding nucleus cytoplasm intermediate filament plasma membrane	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
232252_at	-0.681	9.385	-4.401	4.994e-04	0.065	0.063	DUSP27	dual specificity phosphatase 27 (putative)	1	165330710	AI822125	92235	1q22-q24	Hs.632462	2	protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity phosphatase activity
217882_at	-0.856	10.571	-4.399	5.015e-04	0.065	0.059	TMEM111	transmembrane protein 111	3	-9980635	NM_018447	55831	3p25.3	Hs.475392	6	molecular_function cellular_component biological_process membrane integral to membrane
214039_s_at	-1.068	11.019	-4.395	5.054e-04	0.065	0.052	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	T15777	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
222436_s_at	-0.456	8.492	-4.395	5.061e-04	0.065	0.051	VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	2	-86584063	AF219226	51652	2p24.3-p24.1	Hs.591582	25	protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division	Endocytosis
219233_s_at	0.413	5.366	4.392	5.091e-04	0.065	0.046	GSDMB	gasdermin B	17	-35314373, -35314373	NM_018530	55876	17q12	Hs.306777	12	cytoplasm
225819_at	-0.751	5.926	-4.391	5.098e-04	0.065	0.044	TBRG1	transforming growth factor beta regulator 1	11	123997951	AA576946	84897	11q24.2	Hs.436410	11	DNA binding protein binding nucleus DNA replication cell cycle cell cycle arrest negative regulation of cell proliferation nucleolus to nucleoplasm transport protein stabilization
49329_at	0.406	6.655	4.387	5.137e-04	0.065	0.038	KLHL22	kelch-like 22 (Drosophila)	22	-19125805	N38751	84861	22q11.21	Hs.517419	6	protein binding
219418_at	-0.597	6.396	-4.384	5.169e-04	0.066	0.032	NHEJ1	nonhomologous end-joining factor 1	2	-219648289	NM_024782	79840	2q35	Hs.225988	27	DNA binding nucleus DNA repair double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development response to ionizing radiation B cell differentiation T cell differentiation identical protein binding positive regulation of ligase activity	Non-homologous end-joining
242794_at	0.772	3.715	4.383	5.187e-04	0.066	0.029	MAML3	mastermind-like 3 (Drosophila)	4	-140856995	AI569476	55534	4q28	Hs.586165	7	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
239763_at	0.446	5.742	4.381	5.203e-04	0.066	0.026	PRDM11	PR domain containing 11	11	45072139	AA157112	56981	11p11	Hs.178715	3
213174_at	-0.670	6.200	-4.380	5.215e-04	0.066	0.024	TTC9	tetratricopeptide repeat domain 9	14	70178256	BE675549	23508	14q24.2	Hs.79170	5	binding protein folding
222991_s_at	-0.832	7.157	-4.379	5.220e-04	0.066	0.023	UBQLN1	ubiquilin 1	9	-85464697	AL136643	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
225701_at	0.603	5.259	4.379	5.230e-04	0.066	0.021	AKNA	AT-hook transcription factor	9	-116136254	AK024431	80709	9q32	Hs.494895	5	DNA binding nucleus regulation of transcription
219225_at	-0.580	5.549	-4.377	5.246e-04	0.066	0.018	PGBD5	piggyBac transposable element derived 5	1	-228524014	NM_024554	79605	1q42.13	Hs.520463	3	membrane integral to membrane
224865_at	-0.500	6.929	-4.375	5.268e-04	0.066	0.014	FAR1	fatty acyl CoA reductase 1	11	13646781	N63551	84188	11p15.2	Hs.501991	10	protein binding peroxisome lipid biosynthetic process membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor oxidation reduction
225833_at	-0.788	4.188	-4.374	5.275e-04	0.066	0.013	DAGLB	diacylglycerol lipase, beta	7	-6415272	BE795104	221955	7p22.1	Hs.487498	9	triacylglycerol lipase activity calcium ion binding plasma membrane integral to membrane lipid catabolic process hydrolase activity
235867_at	-0.980	6.134	-4.373	5.285e-04	0.066	0.012	GSTM3	glutathione S-transferase mu 3 (brain)	1	-110078076	AI459140	2947	1p13.3	Hs.2006	96	glutathione transferase activity cytoplasm establishment of blood-nerve barrier metabolic process transferase activity identical protein binding response to estrogen stimulus	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
201198_s_at	-0.742	8.426	-4.373	5.290e-04	0.066	0.011	PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	2	231629852	AI860431	5707	2q37.1	Hs.3887	43	proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
240289_at	-1.593	7.611	-4.371	5.314e-04	0.066	0.007	LOC100131683	hypothetical protein LOC100131683	4		W86910	100131683	4q35.1	Hs.442702
239390_at	-0.605	5.653	-4.366	5.365e-04	0.066	-0.002	GTDC1	glycosyltransferase-like domain containing 1	2	-144420052, -144420050	BE327650	79712	2q22.3	Hs.44780	3	biosynthetic process transferase activity, transferring glycosyl groups
210011_s_at	-0.342	6.699	-4.361	5.416e-04	0.067	-0.011	EWSR1	Ewing sarcoma breakpoint region 1	22	27993997, 27993997	BC000527	2130	22q12.2	Hs.374477	90	nucleotide binding RNA binding calmodulin binding intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding
214959_s_at	-0.794	4.404	-4.361	5.420e-04	0.067	-0.012	API5	apoptosis inhibitor 5	11	43290080	AF229253	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
200962_at	1.152	5.997	4.361	5.424e-04	0.067	-0.012	RPL31	ribosomal protein L31	2	100985122, 100985122	AI348010	6160	2q11.2	Hs.469473	21	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
231875_at	-1.044	4.875	-4.358	5.449e-04	0.067	-0.017	KIF21A	kinesin family member 21A	12	-37973296	AF155117	55605	12q12	Hs.374201	25	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement
217722_s_at	-0.500	11.404	-4.356	5.476e-04	0.067	-0.021	NGRN	neugrin, neurite outgrowth associated	15	88609898	NM_016645	51335	15q26.1	Hs.715556 Hs.716378	2	molecular_function nucleus multicellular organismal development nervous system development neuron differentiation
240607_at	0.523	6.006	4.355	5.486e-04	0.067	-0.023	MIAT	myocardial infarction associated transcript (non-protein coding)	22	25383483	AI692560	440823	22q12.1	Hs.517502	3
236574_at	0.420	5.748	4.354	5.495e-04	0.067	-0.024	LOC284373	hypothetical protein LOC284373	19		AI304870	284373	19q13.41	Hs.188680	1
202583_s_at	-1.030	6.875	-4.352	5.522e-04	0.067	-0.029	RANBP9	RAN binding protein 9	6	-13729708	NM_005493	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
213065_at	-0.586	6.431	-4.351	5.526e-04	0.067	-0.029	ZFC3H1	zinc finger, C3H1-type containing	12	-70289648	AB011118	196441	12q21.1	Hs.527874	4	binding intracellular RNA processing zinc ion binding metal ion binding
225639_at	1.376	6.745	4.350	5.545e-04	0.067	-0.032	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	N21390	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
200958_s_at	-0.559	9.015	-4.347	5.576e-04	0.067	-0.038	SDCBP	syndecan binding protein (syntenin)	8	59628281	NM_005625	6386	8q12	Hs.200804	39	interleukin-5 receptor binding nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton plasma membrane interleukin-5 receptor complex adherens junction focal adhesion protein targeting to membrane substrate-bound cell migration, cell extension intracellular signaling cascade Ras protein signal transduction synaptic transmission cytoskeletal adaptor activity actin cytoskeleton organization cell junction melanosome syndecan binding protein heterodimerization activity protein N-terminus binding
231014_at	0.468	4.971	4.346	5.586e-04	0.067	-0.039	TRIM50	tripartite motif-containing 50	7	-72364470	BG413545	135892	7q11.23	Hs.647053	4	protein binding intracellular cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
200740_s_at	-0.497	9.325	-4.342	5.635e-04	0.068	-0.047	SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	21	-45049959	NM_006936	6612	21q22.3	Hs.474005	40	kinetochore protein binding cytoplasm protein sumoylation modification-dependent protein catabolic process
214265_at	0.614	5.193	4.341	5.644e-04	0.068	-0.049	ITGA8	integrin, alpha 8	10	-15599093	AI193623	8516	10p13	Hs.171311	15	metanephros development receptor activity calcium ion binding protein binding cell-matrix adhesion integrin-mediated signaling pathway multicellular organismal development nervous system development memory integrin complex membrane integral to membrane cell-cell adhesion cell projection organization cell differentiation extracellular matrix organization positive regulation of transforming growth factor beta receptor signaling pathway inner ear morphogenesis apical part of cell	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
205160_at	0.712	6.679	4.336	5.694e-04	0.068	-0.057	PEX11A	peroxisomal biogenesis factor 11 alpha	15	-88027290	AL360141	8800	15q26.1	Hs.31034	9	peroxisome peroxisomal membrane integral to peroxisomal membrane signal transduction membrane integral to membrane peroxisome fission
202917_s_at	-2.507	5.693	-4.335	5.707e-04	0.068	-0.059	S100A8	S100 calcium binding protein A8	1	-151629131	NM_002964	6279	1q21	Hs.416073	91	calcium ion binding protein binding inflammatory response
242545_at	-0.644	5.907	-4.335	5.715e-04	0.068	-0.060	TTLL11	tubulin tyrosine ligase-like family, member 11	9	-123791010, -123624025	AA007347	158135	9q33.2	Hs.640663 Hs.644262	5	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process ligase activity
208997_s_at	1.134	7.151	4.334	5.719e-04	0.068	-0.061	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	11	-73363363	U82819	7351	11q13	Hs.80658	153	response to superoxide binding mitochondrion mitochondrial inner membrane transport mitochondrial transport proton transport membrane integral to membrane
200995_at	-0.892	8.955	-4.332	5.745e-04	0.068	-0.065	IPO7	importin 7	11	9362744	AI741392	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
224898_at	-0.801	5.465	-4.331	5.762e-04	0.068	-0.068	WDR26	WD repeat domain 26	1	-222639467	BG177759	80232	1q42.11-q42.12	Hs.497873	8	cytoplasm
210544_s_at	-0.798	6.810	-4.328	5.791e-04	0.068	-0.072	ALDH3A2	aldehyde dehydrogenase 3 family, member A2	17	19492655, 19492655	BC002430	224	17p11.2	Hs.499886	27	3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity aldehyde dehydrogenase [NAD(P)+] activity mitochondrial inner membrane endoplasmic reticulum cellular aldehyde metabolic process lipid metabolic process central nervous system development peripheral nervous system development epidermis development membrane integral to membrane oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
204671_s_at	0.777	5.498	4.328	5.798e-04	0.068	-0.073	ANKRD6	ankyrin repeat domain 6	6	90199615	BE677131	22881	6q14.2-q16.1	Hs.702213	9	protein binding
1562403_a_at	-0.822	7.147	-4.328	5.799e-04	0.068	-0.074	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3	14	-69580686, -69580686, -69580686	AK096553	6547	14q24.1	Hs.337696	16	calcium:sodium antiporter activity calcium ion binding calmodulin binding ion transport sodium ion transport calcium ion transport cell communication antiporter activity membrane integral to membrane sodium ion binding	Calcium signaling pathway
224566_at	-1.339	10.652	-4.327	5.803e-04	0.068	-0.074	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AI042152	283131	11q13.1	Hs.523789 Hs.648467	6
208266_at	0.556	4.306	4.327	5.806e-04	0.068	-0.075	C8orf17	chromosome 8 open reading frame 17	8		NM_020237	56988	8q24.3	Hs.283098	2	cytoplasm endoplasmic reticulum endoplasmic reticulum membrane microsome membrane
218843_at	0.969	6.142	4.322	5.861e-04	0.068	-0.083	FNDC4	fibronectin type III domain containing 4	2	-27568254	NM_022823	64838	2p23.3	Hs.27836 Hs.718524	6	membrane integral to membrane
219441_s_at	0.638	5.096	4.322	5.866e-04	0.068	-0.084	LRRK1	leucine-rich repeat kinase 1	15	99276982	NM_024652	79705	15q26.3	Hs.407918	16	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding GTP binding intracellular cytoplasm protein amino acid phosphorylation small GTPase mediated signal transduction transferase activity manganese ion binding
204422_s_at	1.491	3.435	4.321	5.870e-04	0.068	-0.085	FGF2	fibroblast growth factor 2 (basic)	4	123967312	NM_002006	2247	4q26-q27	Hs.284244	320	activation of MAPKK activity activation of MAPK activity induction of an organ positive regulation of protein amino acid phosphorylation protein binding extracellular region extracellular region extracellular space apoptosis chemotaxis signal transduction Ras protein signal transduction multicellular organismal development nervous system development growth factor activity heparin binding negative regulation of cell proliferation fibroblast growth factor receptor signaling pathway organ morphogenesis glial cell differentiation positive regulation of granule cell precursor proliferation lung development positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration positive regulation of cell differentiation positive regulation of angiogenesis regulation of retinal cell programmed cell death positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
206263_at	-0.568	4.371	-4.321	5.870e-04	0.068	-0.085	FMO4	flavin containing monooxygenase 4	1	169550109	NM_002022	2329	1q23-q25	Hs.386502	11	monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome xenobiotic metabolic process membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction	Drug metabolism - cytochrome P450
206995_x_at	0.625	4.988	4.320	5.883e-04	0.068	-0.087	SCARF1	scavenger receptor class F, member 1	17	-1483902, -1483901	NM_003693	8578	17p13.3	Hs.647430	6	scavenger receptor activity protein binding cholesterol catabolic process receptor-mediated endocytosis cell adhesion membrane integral to membrane low-density lipoprotein binding
221217_s_at	-0.722	9.440	-4.314	5.961e-04	0.068	-0.099	A2BP1	ataxin 2-binding protein 1	16	6009132, 6763810, 7322751	NM_018723	54715	16p13.3	Hs.459842	22	nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport
221432_s_at	0.599	7.402	4.313	5.966e-04	0.068	-0.100	SLC25A28	solute carrier family 25, member 28	10	-101360264	NM_031212	81894	10q23-q24	Hs.403790	6	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
224843_at	-0.595	4.779	-4.313	5.970e-04	0.068	-0.100	SLAIN2	SLAIN motif family, member 2	4	48038369	AB040891	57606	4p11	Hs.479677	5
202059_s_at	-0.887	7.441	-4.312	5.983e-04	0.068	-0.102	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	NM_002264	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
207188_at	0.527	5.404	4.312	5.989e-04	0.068	-0.103	CDK3	cyclin-dependent kinase 3	17	71508581	NM_001258	1018	17q22-qter	Hs.706766	21	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation cell cycle mitosis cell proliferation transferase activity cell division
202313_at	-0.440	8.633	-4.309	6.024e-04	0.068	-0.108	PPP2R2A	protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform	8	26204950	NM_002717	5520	8p21.2	Hs.146339	44	protein phosphatase type 2A complex protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation signal transduction protein phosphatase type 2A regulator activity response to morphine	Tight junction
209825_s_at	-0.775	6.658	-4.307	6.050e-04	0.068	-0.113	UCK2	uridine-cytidine kinase 2	1	164063513	BC002906	7371	1q23	Hs.458360	22	nucleotide binding molecular_function uridine kinase activity ATP binding cellular_component cytosol metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways
228561_at	-1.188	6.687	-4.306	6.063e-04	0.068	-0.114	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	9	4669565	BF510563	55664	9p24.1	Hs.561954	6	protein binding cytoplasm
221052_at	0.405	3.135	4.305	6.072e-04	0.068	-0.116	TDRKH	tudor and KH domain containing	1	-150012579, -150010664	NM_006862	11022	1q21	Hs.144439	8	RNA binding
230919_at	0.843	3.345	4.302	6.107e-04	0.068	-0.121	ZNF233	zinc finger protein 233	19	49455915	AW006620	353355	19q13.31	Hs.466891	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201079_at	-0.854	9.237	-4.300	6.130e-04	0.068	-0.124	SYNGR2	synaptogyrin 2	17	73676265	NM_004710	9144	17q25.3	Hs.464210 Hs.708616	5	integral to plasma membrane membrane
224827_at	-0.883	6.243	-4.300	6.136e-04	0.068	-0.125	UBTD2	ubiquitin domain containing 2	5	-171569254	AK022894	92181	5q35.1	Hs.131570 Hs.716824	7	cytoplasm
222858_s_at	0.579	5.408	4.298	6.157e-04	0.068	-0.128	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	AI632216	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
208370_s_at	-1.057	7.490	-4.298	6.160e-04	0.068	-0.129	RCAN1	regulator of calcineurin 1	21	-34810653, -34810653, -34810653	NM_004414	1827	21q22.1-q22.2 21q22.12	Hs.282326	45	transcription factor activity protein binding nucleus cytoplasm signal transduction central nervous system development blood circulation response to mechanical stimulus calcium-mediated signaling response to estrogen stimulus regulation of phosphoprotein phosphatase activity skeletal muscle fiber development negative regulation of smooth muscle cell differentiation
208744_x_at	-0.571	6.312	-4.297	6.170e-04	0.068	-0.130	HSPH1	heat shock 105kDa/110kDa protein 1	13	-30608762	BG403660	10808	13q12.3	Hs.36927	25	nucleotide binding ATP binding cytoplasm response to unfolded protein
217993_s_at	-0.682	9.801	-4.296	6.177e-04	0.068	-0.131	MAT2B	methionine adenosyltransferase II, beta	5	162862808, 162865162	NM_013283	27430	5q34-q35	Hs.54642	20	catalytic activity protein binding intracellular nucleus S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process metabolic process dTDP-4-dehydrorhamnose reductase activity extracellular polysaccharide biosynthetic process methionine adenosyltransferase complex methionine adenosyltransferase regulator activity methionine adenosyltransferase regulator activity	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
233557_s_at	-0.439	5.174	-4.295	6.191e-04	0.068	-0.134	MON1B	MON1 homolog B (yeast)	16	75782336	AK023374	22879	16q23.1	Hs.513743	6
213166_x_at	0.837	8.455	4.292	6.231e-04	0.069	-0.139	FAM128A	family with sequence similarity 128, member A	2	-131958002	BG332462	653784	2q21.1	Hs.655067	2
212002_at	-0.471	7.210	-4.290	6.252e-04	0.069	-0.143	C1orf144	chromosome 1 open reading frame 144	1	16566169	AL561657	26099	1p36.13	Hs.252967	2
200972_at	-0.840	10.380	-4.289	6.274e-04	0.069	-0.146	TSPAN3	tetraspanin 3	15	-75125385	BC000704	10099	15q24.3	Hs.5062 Hs.716484	8	membrane integral to membrane
214328_s_at	-0.476	11.601	-4.286	6.311e-04	0.069	-0.151	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	R01140	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
223309_x_at	-0.612	7.849	-4.285	6.314e-04	0.069	-0.152	PNPLA8	patatin-like phospholipase domain containing 8	7	-107899306	BG025248	50640	7q31	Hs.617340	13	lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm
210691_s_at	-0.601	8.089	-4.285	6.316e-04	0.069	-0.152	CACYBP	calcyclin binding protein	1	173235193, 173235514	AF275803	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
241233_x_at	0.444	7.465	4.282	6.357e-04	0.069	-0.158	C21orf81	ankyrin repeat domain 20 family, member A3 pseudogene	21	-14237966	AI978581	391267	21q11.2	Hs.364456	2
201457_x_at	-0.626	6.984	-4.282	6.359e-04	0.069	-0.158	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	10	124903749	AF081496	9184	10q26	Hs.418533	28	kinetochore protein binding nucleus nucleolus cytosol mitosis mitotic cell cycle checkpoint cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle
224767_at	-0.443	6.011	-4.282	6.363e-04	0.069	-0.159	RPL37	ribosomal protein L37	5	-40867186	AL044126	6167	5p13	Hs.558601 Hs.80545	12	structural constituent of ribosome protein binding intracellular cytosol ribosome translational elongation zinc ion binding rRNA binding cytosolic large ribosomal subunit metal ion binding	Ribosome
223716_s_at	-0.534	9.448	-4.281	6.368e-04	0.069	-0.160	ZRANB2	zinc finger, RAN-binding domain containing 2	1	-71301561	AF065391	9406	1p31	Hs.194718	18	transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding
226563_at	-0.555	6.864	-4.279	6.400e-04	0.069	-0.164	SMAD2	SMAD family member 2	18	-43613464, -43613463, -43613463	BF793454	4087	18q21.1	Hs.12253 Hs.705764	206	mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol	Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer
200593_s_at	-0.450	7.885	-4.278	6.410e-04	0.069	-0.165	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	BC003621	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
215307_at	0.606	3.799	4.274	6.460e-04	0.069	-0.173	ZNF529	zinc finger protein 529	19	-41762996, -41726357, -41726357	AL109722	57711	19q13.13	Hs.708146	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204706_at	0.511	6.578	4.274	6.465e-04	0.069	-0.173	INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	9	-138442892	NM_019892	56623	9q34.3	Hs.120998	5	Golgi membrane inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity cellular_component Golgi apparatus lipid metabolic process biological_process membrane hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
227973_at	-0.883	6.770	-4.273	6.471e-04	0.069	-0.174	C2orf69	chromosome 2 open reading frame 69	2	200484223	BF130937	205327	2q33.1	Hs.471040	3	extracellular region
202815_s_at	-0.809	6.944	-4.272	6.486e-04	0.069	-0.176	HEXIM1	hexamethylene bis-acetamide inducible 1	17	40580466	NM_006460	10614	17q21.31	Hs.586945 Hs.634944 Hs.716487	28	negative regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm heart development specific transcriptional repressor activity snRNA binding regulation of transcription negative regulation of cyclin-dependent protein kinase activity
225365_at	-0.640	5.561	-4.271	6.499e-04	0.069	-0.178	ZDHHC20	zinc finger, DHHC-type containing 20	13	-20848507	BG249221	253832	13q12.11	Hs.564611 Hs.693749	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
201899_s_at	-0.507	9.213	-4.270	6.512e-04	0.069	-0.180	UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	X	118592526, 118598325	NM_003336	7319	Xq24-q25	Hs.379466	16	nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination	Ubiquitin mediated proteolysis
1569566_at	-1.401	4.803	-4.269	6.528e-04	0.069	-0.182	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	BC028196	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
227135_at	-0.468	5.638	-4.266	6.565e-04	0.070	-0.187	NAAA	N-acylethanolamine acid amidase	4	-77053832, -77050831	AI436803	27163	4q21.1	Hs.437365	12	molecular_function cellular_component cytoplasm lysosome lipid metabolic process biological_process hydrolase activity
213864_s_at	-0.755	9.661	-4.261	6.637e-04	0.070	-0.197	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AI985751	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
1555882_at	-1.328	3.612	-4.257	6.695e-04	0.071	-0.205	SPIN3	spindlin family, member 3	X	-57033988, -57019529	AJ271379	169981	Xp11.21	Hs.522672	6	gamete generation
226592_at	0.518	5.056	4.251	6.771e-04	0.071	-0.216	ZNF618	zinc finger protein 618	9	115678382	AA031404	114991	9q32	Hs.349208	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity
208763_s_at	-0.798	9.335	-4.242	6.892e-04	0.072	-0.232	TSC22D3	TSC22 domain family, member 3	X	-106843107, -106843107, -106843107	AL110191	1831	Xq22.3	Hs.716410	24	transcription factor activity regulation of transcription, DNA-dependent
219109_at	0.900	6.414	4.242	6.896e-04	0.072	-0.233	SPAG16	sperm associated antigen 16	2	213857360, 213857360	NM_024532	79582	2q34	Hs.602792 Hs.715620	6	cytoplasm cilium flagellum cell projection organization
203423_at	1.613	6.369	4.240	6.921e-04	0.072	-0.236	RBP1	retinol binding protein 1, cellular	3	-140727937, -140727317, -140718965	NM_002899	5947	3q23	Hs.529571	31	transporter activity cytoplasm transport lipid binding retinal binding retinol binding retinol metabolic process retinoic acid metabolic process
201381_x_at	-0.424	9.087	-4.239	6.935e-04	0.072	-0.238	CACYBP	calcyclin binding protein	1	173235193, 173235514	AF057356	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
212586_at	-0.801	9.942	-4.239	6.936e-04	0.072	-0.238	CAST	calpastatin	5	96023696, 96064251, 96104999	AA195244	831	5q15	Hs.436186	60	protein binding calcium-dependent cysteine-type endopeptidase inhibitor activity
223908_at	-0.918	4.374	-4.234	7.004e-04	0.072	-0.247	HDAC8	histone deacetylase 8	X	-71466090	AF212246	55869	Xq13	Hs.310536	23	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter nuclear chromosome histone deacetylase activity nucleus cytoplasm chromatin assembly or disassembly transcription factor binding chromatin modification histone deacetylation hydrolase activity regulation of transcription
206685_at	0.447	3.409	4.234	7.004e-04	0.072	-0.247	HCG4	HLA complex group 4	6	-29866787, -1211427, -1013559	NM_018985	54435	6p21.3	Hs.660431	2
209288_s_at	-1.267	7.632	-4.233	7.023e-04	0.072	-0.249	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	2	-37724246	AL136842	10602	2p21	Hs.369574	17	protein binding cytoskeletal regulatory protein binding cytoplasm signal transduction regulation of cell shape actin cytoskeleton membrane
210807_s_at	0.811	4.907	4.232	7.033e-04	0.072	-0.251	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	AF049608	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
222847_s_at	-0.648	5.277	-4.232	7.034e-04	0.072	-0.251	EGLN3	egl nine homolog 3 (C. elegans)	14	-33463171	AI378406	112399	14q13.1	Hs.135507	26	iron ion binding protein binding nucleus cytoplasm apoptosis oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
221606_s_at	-0.849	5.373	-4.231	7.047e-04	0.072	-0.252	NSBP1	nucleosomal binding protein 1	X	-80255855	BC005342	79366	Xq13.3	Hs.282204	7	chromatin DNA binding chromatin binding nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase I promoter transcription activator activity
1554678_s_at	-0.562	8.367	-4.231	7.060e-04	0.072	-0.254	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	AB066484	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
237560_at	0.725	5.661	4.227	7.103e-04	0.072	-0.260	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	AI015881	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
218033_s_at	-1.116	5.345	-4.227	7.105e-04	0.072	-0.260	SNN	stannin	16	11669801	NM_003498	8303	16p13	Hs.700592	11	response to stress response to abiotic stimulus membrane integral to membrane
235042_at	-1.618	9.868	-4.226	7.129e-04	0.072	-0.263	XIRP1	xin actin-binding repeat containing 1	3	-39199710	AW755250	165904	3p22.2	Hs.447868	7	actin binding fascia adherens negative regulation of cell proliferation actin cytoskeleton organization cell junction regulation of membrane potential sarcomere organization cardiac muscle cell development
240459_at	-0.476	3.787	-4.220	7.213e-04	0.073	-0.274	YTHDC1	YTH domain containing 1	4	-68858699	AW467048	91746	4q13.2	Hs.175955	18	nucleus mRNA processing RNA splicing
221519_at	-0.578	7.992	-4.217	7.251e-04	0.073	-0.279	FBXW4	F-box and WD repeat domain containing 4	10	-103360410	AF281859	6468	10q24	Hs.500822	16	ubiquitin ligase complex molecular_function ubiquitin-dependent protein catabolic process multicellular organismal development Wnt receptor signaling pathway embryonic limb morphogenesis limb development
224840_at	-1.384	10.230	-4.214	7.305e-04	0.074	-0.285	FKBP5	FK506 binding protein 5	6	-35656311, -35649339, -35649339, -35649339	AI753747	2289	6p21.3-p21.2	Hs.407190	50	peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding
212565_at	-0.839	6.648	-4.208	7.395e-04	0.075	-0.297	STK38L	serine/threonine kinase 38 like	12	27288344	BE302191	23012	12p11.23	Hs.184523	15	nucleotide binding magnesium ion binding actin binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation protein kinase cascade actin cytoskeleton transferase activity regulation of cellular component organization
201646_at	-0.974	7.181	-4.206	7.419e-04	0.075	-0.300	SCARB2	scavenger receptor class B, member 2	4	-77298917	AA885297	950	4q21.1	Hs.349656 Hs.714206	24	receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane	Lysosome
1560145_at	-0.591	5.884	-4.204	7.448e-04	0.075	-0.303	MKLN1	muskelin 1, intracellular mediator containing kelch motifs	7	130445394, 130663134	BQ942131	4289	7q32	Hs.44693	13	protein binding cytoplasm signal transduction
238974_at	-0.763	9.063	-4.203	7.464e-04	0.075	-0.305	C2orf69	chromosome 2 open reading frame 69	2	200484223	N47077	205327	2q33.1	Hs.471040	3	extracellular region
214709_s_at	-0.663	11.707	-4.203	7.470e-04	0.075	-0.306	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	Z22551	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
213745_at	-1.143	2.958	-4.197	7.557e-04	0.076	-0.317	ATRNL1	attractin-like 1	10	116843113	AW151108	26033	10q26	Hs.501127	3	binding sugar binding membrane integral to membrane
218520_at	-0.694	6.533	-4.195	7.590e-04	0.076	-0.321	TBK1	TANK-binding kinase 1	12	63132203	NM_013254	29110	12q14.1	Hs.505874 Hs.607889	51	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation response to virus transferase activity positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms innate immune response	Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway
210156_s_at	-0.636	9.210	-4.195	7.593e-04	0.076	-0.321	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	6	150112523	D25547	5110	6q24-q25	Hs.279257	25	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding
226247_at	-0.719	7.755	-4.194	7.605e-04	0.076	-0.322	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	10	124124209, 124141832	AI346026	59338	10q26.13	Hs.643512	16	phospholipid binding cellular_component nucleus cytoplasm plasma membrane biological_process
226398_s_at	0.526	7.559	4.188	7.704e-04	0.076	-0.334	C10orf4	chromosome 10 open reading frame 4	10	-95418318	AI804930	118924	10q23.33	Hs.658192	7	protein binding nucleus
203711_s_at	-0.630	7.456	-4.187	7.708e-04	0.076	-0.335	HIBCH	3-hydroxyisobutyryl-Coenzyme A hydrolase	2	-190777604	NM_014362	26275	2q32.2	Hs.656685	8	3-hydroxyisobutyryl-CoA hydrolase activity protein binding mitochondrion metabolic process branched chain family amino acid catabolic process hydrolase activity	Valine, leucine and isoleucine degradation beta-Alanine metabolism Propanoate metabolism Metabolic pathways
209018_s_at	-0.563	9.533	-4.186	7.728e-04	0.076	-0.337	PINK1	PTEN induced putative kinase 1	1	20832534	BF432478	65018	1p36	Hs.389171	105	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding mitochondrion mitochondrial outer membrane protein amino acid phosphorylation response to stress protein kinase cascade membrane integral to membrane transferase activity positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion	Parkinson's disease
217856_at	-0.950	5.399	-4.183	7.780e-04	0.076	-0.343	RBM8A	RNA binding motif protein 8A	1	144218994	AF182415	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
233825_s_at	-0.982	7.468	-4.181	7.806e-04	0.076	-0.346	CD99L2	CD99 molecule-like 2	X	-149685466	AU158444	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
202723_s_at	-0.782	6.727	-4.181	7.812e-04	0.076	-0.347	FOXO1	forkhead box O1	13	-40027800	AW117498	2308	13q14.1	Hs.370666	140	blood vessel development transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent anti-apoptosis insulin receptor signaling pathway transcription activator activity regulation of cell proliferation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter	Insulin signaling pathway Pathways in cancer Prostate cancer
208624_s_at	-0.851	6.994	-4.180	7.819e-04	0.076	-0.348	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	3	185515049, 185515664, 185520956	BE966878	1981	3q27-qter	Hs.433750	91	RNA binding translation initiation factor activity protein binding cytoplasm cytosol regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
203466_at	0.488	6.450	4.180	7.823e-04	0.076	-0.348	MPV17	MpV17 mitochondrial inner membrane protein	2	-27385863	NM_002437	4358	2p23.3	Hs.75659	17	mitochondrial genome maintenance molecular_function mitochondrion mitochondrial inner membrane integral to peroxisomal membrane oxygen and reactive oxygen species metabolic process membrane integral to membrane homeostatic process
231157_at	-0.736	5.922	-4.177	7.876e-04	0.077	-0.354	TTLL11	tubulin tyrosine ligase-like family, member 11	9	-123791010, -123624025	BE856668	158135	9q33.2	Hs.640663 Hs.644262	5	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process ligase activity
233669_s_at	-0.530	7.947	-4.176	7.885e-04	0.077	-0.356	TRIM54	tripartite motif-containing 54	2	27359103	AA868267	57159	2p23.3	Hs.516036	5	signal transducer activity protein binding intracellular cytoplasm cytoskeleton microtubule microtubule associated complex microtubule-based process negative regulation of microtubule depolymerization signal transduction multicellular organismal development microtubule binding zinc ion binding Z disc cell differentiation metal ion binding
207705_s_at	1.018	6.329	4.172	7.948e-04	0.077	-0.363	NINL	ninein-like	20	-25381337	NM_025176	22981	20p11.22-p11.1	Hs.696157	13	calcium ion binding cytoplasm centrosome microtubule
236193_at	-1.254	5.263	-4.167	8.038e-04	0.078	-0.373	HIST1H2BC	histone cluster 1, H2bc	6	-26231673	AA037483	8347	6p21.3	Hs.658713	10	nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly defense response to bacterium	Systemic lupus erythematosus
200993_at	-0.558	10.084	-4.167	8.039e-04	0.078	-0.373	IPO7	importin 7	11	9362744	AA939270	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
236250_at	-0.478	5.927	-4.166	8.052e-04	0.078	-0.375	AFG3L1	AFG3 ATPase family gene 3-like 1 (S. cerevisiae)	16	88566488, 88566488	AI859065	172	16q24.3	Hs.534773	6
216115_at	-0.460	5.019	-4.164	8.082e-04	0.078	-0.378	NF1	neurofibromin 1	17	26446120, 26446120	AK024873	4763	17q11.2	Hs.113577	204	osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction	MAPK signaling pathway
220539_at	-0.894	6.761	-4.164	8.082e-04	0.078	-0.378	C10orf92	chromosome 10 open reading frame 92	10	-134471886	NM_017609	54777	10q26.3	Hs.298038	6
215071_s_at	-0.914	7.430	-4.161	8.140e-04	0.078	-0.385	HIST1H2AC	histone cluster 1, H2ac	6	26232351	AL353759	8334	6p21.3	Hs.699831	19	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
235798_at	-1.059	6.282	-4.159	8.166e-04	0.078	-0.388	TMEM170B	transmembrane protein 170B	6	11646496	BE671123	100113407	6p24.2	Hs.146317	1	membrane integral to membrane
218265_at	-0.496	6.809	-4.157	8.194e-04	0.078	-0.391	SECISBP2	SECIS binding protein 2	9	91123231	NM_024077	79048	9q22.2	Hs.59804	20	RNA binding mRNA 3'-UTR binding nucleus translation
228594_at	0.405	7.140	4.157	8.198e-04	0.078	-0.391	C5orf33	chromosome 5 open reading frame 33	5	-36228450, -36228450	H94910	133686	5p13.2	Hs.81907	3	NAD+ kinase activity metabolic process
222611_s_at	-0.824	5.386	-4.155	8.235e-04	0.078	-0.395	PSPC1	paraspeckle component 1	13	-19175008, -19146895	AA969958	55269	13q12.11	Hs.213198	9	nucleotide binding RNA binding protein binding nucleus nucleolus cytoplasm nuclear matrix regulation of transcription
204185_x_at	-0.761	9.597	-4.154	8.243e-04	0.078	-0.396	PPID	peptidylprolyl isomerase D	4	-159849728	NM_005038	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
218954_s_at	-0.788	6.227	-4.154	8.248e-04	0.078	-0.397	BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	8	-37820560	AF298153	55290	8p11.23	Hs.709301	11	protein binding nucleus transcription factor complex transcription initiation regulation of transcription, DNA-dependent zinc ion binding transcription regulator activity metal ion binding
222431_at	0.721	6.362	4.154	8.257e-04	0.078	-0.398	SPIN1	spindlin 1	9	90193116	AL136719	10927	9q22.1-q22.3	Hs.146804	16	nucleus spindle cell cycle multicellular organismal development gamete generation
210170_at	-1.661	9.678	-4.152	8.280e-04	0.078	-0.400	PDLIM3	PDZ and LIM domain 3	4	-186659844	BC001017	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
218024_at	0.777	10.668	4.152	8.286e-04	0.078	-0.401	BRP44L	brain protein 44-like	6	-166698399	NM_016098	51660	6q27	Hs.172755	7	molecular_function cellular_component mitochondrion biological_process
225049_at	-0.639	9.138	-4.149	8.341e-04	0.078	-0.407	BLOC1S2	biogenesis of lysosomal organelles complex-1, subunit 2	10	-102023702, -102023702	BF382281	282991	10q24.31	Hs.34906	12	gamma-tubulin complex centrosome BLOC-1 complex melanosome organization identical protein binding regulation of apoptosis gamma-tubulin binding platelet dense granule organization
218984_at	-0.639	6.570	-4.146	8.391e-04	0.079	-0.413	PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	7	-104884195	NM_019042	54517	7q22.3	Hs.520619	5	pseudouridine synthesis RNA binding tRNA processing pseudouridine synthase activity isomerase activity
201096_s_at	-0.524	7.868	-4.144	8.418e-04	0.079	-0.416	ARF4	ADP-ribosylation factor 4	3	-57532129	AL537042	378	3p21.2-p21.1	Hs.695943	19	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
1567014_s_at	-0.714	5.957	-4.138	8.530e-04	0.079	-0.428	NFE2L2	nuclear factor (erythroid-derived 2)-like 2	2	-177803279, -177803278	AF323119	4780	2q31	Hs.715540	141	transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity
232119_at	-1.117	7.352	-4.137	8.543e-04	0.079	-0.429	SYNPO2	synaptopodin 2	4	120029443, 120029443	BF984227	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
235261_at	-0.693	10.438	-4.136	8.550e-04	0.079	-0.430	UNC45B	unc-45 homolog B (C. elegans)	17	30498948	AI800785	146862	17q12	Hs.379636	4	binding multicellular organismal development muscle organ development cell differentiation
204784_s_at	-1.819	8.892	-4.135	8.572e-04	0.079	-0.432	MLF1	myeloid leukemia factor 1	3	159771646	NM_022443	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
217976_s_at	-0.691	7.682	-4.134	8.588e-04	0.079	-0.434	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	3	-32542470	NM_016141	51143	3p22.3	Hs.529495	11	nucleotide binding motor activity ATP binding microtubule dynein complex
228962_at	-0.827	7.188	-4.134	8.595e-04	0.079	-0.435	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	BF507941	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
1559965_at	-0.734	5.394	-4.131	8.653e-04	0.080	-0.441	LOC100192378	hypothetical LOC100192378	8	-77685669	BC037827	100192378	8q21.11	Hs.648649	2
220044_x_at	-0.523	8.877	-4.129	8.676e-04	0.080	-0.443	LUC7L3	LUC7-like 3 (S. cerevisiae)	17	46151975	NM_016424	51747	17q21.33	Hs.130293	15	DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck
228790_at	-0.961	6.461	-4.129	8.686e-04	0.080	-0.444	FAM110B	family with sequence similarity 110, member B	8	59069666	AW264082	90362	8q12.1	Hs.154652	7	cytoplasm mitochondrion centrosome
1555741_at	0.488	3.722	4.129	8.690e-04	0.080	-0.445	MRAP	melanocortin 2 receptor accessory protein	21	32585994, 32585994	AF483549	56246	21q22.1	Hs.584940	12	cytoplasm endoplasmic reticulum plasma membrane integral to membrane perinuclear region of cytoplasm
221567_at	-0.458	8.126	-4.127	8.714e-04	0.080	-0.447	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	16	65765370	AF064599	8996	16q21-q23	Hs.513667	22	RNA binding intracellular nucleus nucleolus cytoplasm cytosol mRNA processing anti-apoptosis RNA splicing identical protein binding regulation of apoptosis
220340_at	1.250	6.134	4.126	8.740e-04	0.080	-0.450	KIAA1772	KIAA1772	18	17076200	NM_024935	80000	18q11.1-q11.2	Hs.149020	4	membrane integral to membrane
210719_s_at	-0.645	5.457	-4.124	8.770e-04	0.080	-0.453	HMG20B	high-mobility group 20B	19	3523942	BC002552	10362	19p13.3	Hs.406534	18	transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle chromatin modification
217873_at	-1.101	9.662	-4.121	8.821e-04	0.080	-0.458	CAB39	calcium binding protein 39	2	231285800, 231286506	NM_016289	51719	2q37.1	Hs.632536	14	protein binding cytoplasm	mTOR signaling pathway
235440_at	-0.521	4.024	-4.120	8.838e-04	0.080	-0.460	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	11	-18584523	BE780878	144108	11p15.1	Hs.268668 Hs.719399	2
223212_at	-0.580	7.546	-4.120	8.850e-04	0.080	-0.462	ZDHHC16	zinc finger, DHHC-type containing 16	10	99195919, 99195936	BC004535	84287	10q24.1	Hs.76662	6	endoplasmic reticulum apoptosis zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
201938_at	-0.512	10.263	-4.119	8.862e-04	0.080	-0.463	CDK2AP1	cyclin-dependent kinase 2 associated protein 1	12	-122311492	NM_004642	8099	12q24.31	Hs.719107	15	S phase of mitotic cell cycle DNA binding protein binding nucleus cytoplasm DNA-dependent DNA replication protein amino acid phosphorylation cell cycle
217655_at	0.453	3.262	4.117	8.889e-04	0.080	-0.466	LOC100127972	hypothetical LOC100127972	19		BE552409	100127972	19q13.12	Hs.710764 Hs.716895	1
238799_at	-0.544	3.277	-4.117	8.890e-04	0.080	-0.466	ATP5S	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)	14	49848796, 49848796	BE968806	27109	14q21.3	Hs.438489	12	mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o)
205830_at	2.159	4.555	4.116	8.922e-04	0.080	-0.469	CLGN	calmegin	4	-141529056	NM_004362	1047	4q28.3-q31.1	Hs.86368	11	calcium ion binding endoplasmic reticulum protein folding single fertilization membrane integral to membrane unfolded protein binding
240744_at	0.765	5.173	4.115	8.930e-04	0.080	-0.470	CPA5	carboxypeptidase A5	7	129771865, 129771865	AW184014	93979	7q32	Hs.567642	9	metallocarboxypeptidase activity extracellular region proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
222700_at	-0.945	7.622	-4.113	8.970e-04	0.080	-0.474	ATL2	atlastin GTPase 2	2	-38375534	AV700003	64225	2p22.2-p22.1	Hs.594950	8	nucleotide binding GTPase activity GTP binding membrane integral to membrane
204094_s_at	-0.633	8.315	-4.111	9.012e-04	0.080	-0.478	TSC22D2	TSC22 domain family, member 2	3	151609477	NM_014779	9819	3q25.1	Hs.665220 Hs.715600	5	transcription factor activity regulation of transcription, DNA-dependent
221743_at	-0.465	10.502	-4.110	9.028e-04	0.080	-0.480	CUGBP1	CUG triplet repeat, RNA binding protein 1	11	-47446520, -47446520, -47446520	AI472139	10658	11p11	Hs.632137	34	nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding
212006_at	-0.575	8.019	-4.105	9.117e-04	0.081	-0.489	UBXN4	UBX domain protein 4	2	136215658	AU149908	23190	2q21.3	Hs.591242	12	protein binding nucleus nuclear envelope endoplasmic reticulum response to unfolded protein membrane integral to membrane
219737_s_at	-1.260	5.413	-4.103	9.151e-04	0.081	-0.492	PCDH9	protocadherin 9	13	-65774967	AI524125	5101	13q14.3-q21.1	Hs.654709 Hs.719302	8	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
230098_at	-0.697	7.466	-4.103	9.157e-04	0.081	-0.493	PHF20L1	PHD finger protein 20-like 1	8	133856785, 133856785, 133856785	AW612407	51105	8q24.22	Hs.304362	4	nucleic acid binding protein binding zinc ion binding metal ion binding
205374_at	-0.486	13.454	-4.095	9.308e-04	0.082	-0.508	SLN	sarcolipin	11	-107083310	NM_003063	6588	11q22-q23	Hs.334629	12	membrane integral to membrane sarcoplasmic reticulum enzyme regulator activity regulation of calcium ion transport
1554574_a_at	-0.636	5.646	-4.093	9.346e-04	0.082	-0.512	CYB5R3	cytochrome b5 reductase 3	22	-41344757, -41344757	AF361370	1727	22q13.2-q13.31 22q13.31-qter	Hs.700572	49	cytochrome-b5 reductase activity cytoplasm mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane hemoglobin complex cholesterol biosynthetic process blood circulation electron carrier activity membrane oxidoreductase activity oxidation reduction	Amino sugar and nucleotide sugar metabolism
228310_at	-0.831	5.551	-4.090	9.393e-04	0.082	-0.516	ENAH	enabled homolog (Drosophila)	1	-223741156	BF223300	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
212268_at	-0.836	6.390	-4.088	9.431e-04	0.083	-0.520	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	6	-2778732	NM_030666	1992	6p25	Hs.381167	18	serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity
214541_s_at	-0.807	5.840	-4.088	9.436e-04	0.083	-0.520	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	AF142418	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
214960_at	-0.630	5.476	-4.087	9.467e-04	0.083	-0.523	API5	apoptosis inhibitor 5	11	43290080	AF229253	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
205149_s_at	-0.838	5.396	-4.084	9.519e-04	0.083	-0.528	CLCN4	chloride channel 4	X	10084984	NM_001830	1183	Xp22.3	Hs.495674	17	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding
206453_s_at	-0.822	11.058	-4.082	9.547e-04	0.083	-0.531	NDRG2	NDRG family member 2	14	-20554761, -20554761	NM_016250	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
202566_s_at	-0.997	9.802	-4.082	9.553e-04	0.083	-0.532	SVIL	supervillin	10	-29786282, -29786282	AF051851	6840	10p11.2	Hs.499209	23	podosome calcium ion binding nucleus cytoplasm plasma membrane cytoskeleton organization skeletal muscle tissue development cell projection costamere actin filament binding
204742_s_at	-0.753	6.154	-4.081	9.581e-04	0.083	-0.534	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	13	32058591	NM_015032	23047	13q12.3	Hs.716441	15	chromatin DNA binding ATP binding nucleus cell cycle mitotic sister chromatid cohesion mitosis negative regulation of cell proliferation identical protein binding cell division
204408_at	0.452	5.554	4.079	9.614e-04	0.083	-0.538	APEX2	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	X	55043504	NM_014481	27301	Xp11.21	Hs.659558	8	DNA binding DNA-(apurinic or apyrimidinic site) lyase activity endonuclease activity intracellular nucleus mitochondrion DNA repair response to DNA damage stimulus zinc ion binding lyase activity	Base excision repair
230055_at	0.554	5.283	4.078	9.626e-04	0.083	-0.539	KHDC1	KH homology domain containing 1	6	-74007758	AL037414	80759	6q13	Hs.715645	4	RNA binding membrane integral to membrane
215559_at	-1.665	5.747	-4.076	9.668e-04	0.083	-0.543	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	16	-16222544, -16150922	AI074459	368	16p13.1	Hs.442182	70	nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus	ABC transporters
224832_at	-0.596	7.087	-4.076	9.672e-04	0.083	-0.543	DUSP16	dual specificity phosphatase 16	12	-12520097	AB051487	80824	12p13	Hs.536535	12	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive	MAPK signaling pathway
212010_s_at	-0.636	10.577	-4.076	9.674e-04	0.083	-0.543	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	AK025647	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
207145_at	-1.080	4.700	-4.076	9.675e-04	0.083	-0.543	MSTN	myostatin	2	-190628670	NM_005259	2660	2q32.2	Hs.41565	55	cytokine activity extracellular region extracellular space transforming growth factor beta receptor signaling pathway muscle organ development growth factor activity growth positive regulation of transcription
206625_at	-1.616	6.668	-4.076	9.684e-04	0.083	-0.544	PRPH2	peripherin 2 (retinal degeneration, slow)	6	-42772310	NM_000322	5961	6p21.2-p12.3	Hs.654489	57	protein binding cell adhesion visual perception membrane integral to membrane response to stimulus retina development in camera-type eye	Amyotrophic lateral sclerosis (ALS)
226561_at	-0.868	5.722	-4.074	9.705e-04	0.083	-0.546	AGFG1	ArfGAP with FG repeats 1	2	228045131	BE551849	3267	2q36.3	Hs.352962	29	DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding
217943_s_at	-0.850	8.997	-4.074	9.714e-04	0.083	-0.547	MAP7D1	MAP7 domain containing 1	1	36394389	NM_018067	55700	1p34.3	Hs.700595	7	spindle
225003_at	-0.576	8.568	-4.073	9.734e-04	0.083	-0.549	TMEM205	transmembrane protein 205	19	-11314451	BF343862	374882	19p13.2	Hs.8036	2	membrane integral to membrane
201898_s_at	-0.496	8.762	-4.072	9.755e-04	0.083	-0.551	UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	X	118592526, 118598325	AI126625	7319	Xq24-q25	Hs.379466	16	nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination	Ubiquitin mediated proteolysis
1555960_at	-0.664	4.400	-4.070	9.792e-04	0.083	-0.554	HINT1	histidine triad nucleotide binding protein 1	5	-130522773, -130522773	AK054976	3094	5q31.2	Hs.483305	26	protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity
201573_s_at	-0.641	8.422	-4.068	9.842e-04	0.083	-0.559	ETF1	eukaryotic translation termination factor 1	5	-137869682	M75715	2107	5q31.1	Hs.483494	32	RNA binding protein binding cytoplasm regulation of translational termination protein amino acid methylation translation release factor activity, codon specific ribosome binding
220929_at	0.427	5.086	4.067	9.860e-04	0.083	-0.561	GALNT8	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)	12	4700012	NM_017417	26290	12p13.3	Hs.511985	2	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding	O-Glycan biosynthesis Metabolic pathways
1555427_s_at	-0.798	5.246	-4.063	9.942e-04	0.084	-0.568	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	AY034482	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
228921_at	0.565	4.254	4.062	9.955e-04	0.084	-0.570	SLC25A42	solute carrier family 25, member 42	19	19035807	AW170609	284439	19p13.11	Hs.303669	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
218735_s_at	1.044	5.646	4.060	9.996e-04	0.084	-0.573	ZNF544	zinc finger protein 544	19	63431881	AA349848	27300	19q13.43	Hs.438994	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1555793_a_at	0.769	4.722	4.060	9.999e-04	0.084	-0.574	ZFP82	zinc finger protein 82 homolog (mouse)	19	-41574700	AL834267	284406	19q13.12	Hs.558734	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225719_s_at	0.441	7.148	4.060	1.000e-03	0.084	-0.574	MRPL55	mitochondrial ribosomal protein L55	1	-226361002	BG497783	128308	1q42.13	Hs.63236	11	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation
235132_at	-0.580	6.248	-4.059	1.002e-03	0.084	-0.576	LOC254128	hypothetical protein LOC254128	2		BF939830	254128	2q14.2	Hs.712685	1
204927_at	0.323	6.532	4.059	1.002e-03	0.084	-0.576	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	11	550970, 551449	NM_003475	8045	11p15.5	Hs.72925	9	DNA binding protein binding nucleus regulation of transcription, DNA-dependent signal transduction
235721_at	0.428	6.811	4.058	1.003e-03	0.084	-0.576	DTX3	deltex homolog 3 (Drosophila)	12	56284870	N62126	196403	12q13.3	Hs.32374	6	protein binding cytoplasm Notch signaling pathway zinc ion binding metal ion binding	Notch signaling pathway
228882_at	0.739	5.286	4.058	1.004e-03	0.084	-0.577	TUB	tubby homolog (mouse)	11	8016755, 8059484	AL042088	7275	11p15.5	Hs.231850 Hs.568986	16	nucleus cytoplasm response to stimulus
226208_at	-1.112	6.233	-4.058	1.004e-03	0.084	-0.578	ZSWIM6	zinc finger, SWIM-type containing 6	5	60663856	AI692595	57688	5q12.1	Hs.650537	5	zinc ion binding metal ion binding
1552616_a_at	0.474	5.767	4.057	1.006e-03	0.084	-0.579	ACACB	acetyl-Coenzyme A carboxylase beta	12	108061584	NM_001093	32	12q24.11	Hs.234898	22	nucleotide binding acetyl-CoA carboxylase activity biotin carboxylase activity ATP binding cytoplasm Golgi apparatus cytosol fatty acid biosynthetic process metabolic process biotin binding membrane ligase activity manganese ion binding regulation of fatty acid oxidation metal ion binding	Fatty acid biosynthesis Pyruvate metabolism Propanoate metabolism Metabolic pathways Insulin signaling pathway Adipocytokine signaling pathway
242835_s_at	-0.663	5.308	-4.054	1.012e-03	0.084	-0.585	LOC728730	hypothetical LOC728730	2		AW772084	728730	2p22.1
203575_at	-0.514	7.110	-4.053	1.014e-03	0.084	-0.587	CSNK2A2	casein kinase 2, alpha prime polypeptide	16	-56749312	NM_001896	1459	16q21	Hs.82201	143	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity protein N-terminus binding regulation of cell cycle	Wnt signaling pathway Adherens junction Tight junction
204000_at	0.522	5.556	4.051	1.018e-03	0.084	-0.590	GNB5	guanine nucleotide binding protein (G protein), beta 5	15	-50200414, -50200414	NM_016194	10681	15q21.2	Hs.155090	26	GTPase activity signal transducer activity protein binding nucleus heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway	Chemokine signaling pathway
226380_at	-0.592	6.509	-4.049	1.022e-03	0.084	-0.594	PTPN21	protein tyrosine phosphatase, non-receptor type 21	14	-88001874	N21442	11099	14q31.3	Hs.437040	10	protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity
235593_at	-1.176	3.420	-4.045	1.031e-03	0.085	-0.602	ZEB2	zinc finger E-box binding homeobox 2	2	-144862052	AL546529	9839	2q22.3	Hs.34871	49	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent nervous system development zinc ion binding negative regulation of transcription phosphatase regulator activity sequence-specific DNA binding SMAD binding metal ion binding
201298_s_at	-0.518	7.583	-4.045	1.032e-03	0.085	-0.602	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	2	-74236718	BC003398	55233	2p13.1	Hs.196437	12	protein binding zinc ion binding metal ion binding
229459_at	-0.617	2.636	-4.044	1.032e-03	0.085	-0.602	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	22	47263951, 47350781	AV723914	25817	22q13.32	Hs.436854 Hs.632788	8	extracellular region membrane integral to membrane
224352_s_at	-0.705	11.148	-4.044	1.033e-03	0.085	-0.603	CFL2	cofilin 2 (muscle)	14	-34249338, -34249338, -34249338	AF134802	1073	14q12	Hs.180141	20	actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
207797_s_at	-0.554	4.932	-4.041	1.038e-03	0.085	-0.608	LRP2BP	LRP2 binding protein	4	-186522026	NM_018409	55805	4q35.1	Hs.558513	4	protein binding cytoplasm
225662_at	-0.621	11.537	-4.034	1.055e-03	0.086	-0.623	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	H28667	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
213831_at	2.383	3.957	4.033	1.055e-03	0.086	-0.623	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	6	32713160	X00452	3117	6p21.3	Hs.387679 Hs.706240	542	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane MHC class II receptor activity MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
227239_at	-1.149	8.467	-4.032	1.059e-03	0.086	-0.626	FAM126A	family with sequence similarity 126, member A	7	-22947402	AV734839	84668	7p15.3	Hs.85603	9	signal transducer activity cellular_component cytoplasm biological_process membrane
221935_s_at	-0.921	5.848	-4.029	1.066e-03	0.087	-0.632	C3orf64	chromosome 3 open reading frame 64	3	-69107057	AK023140	285203	3p14.1	Hs.518059	2	extracellular region endoplasmic reticulum transferase activity, transferring glycosyl groups
221536_s_at	-0.804	6.968	-4.024	1.076e-03	0.087	-0.641	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	3	-195842806	AL136897	55341	3q29	Hs.518505	12	nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export
226184_at	-0.824	6.725	-4.023	1.078e-03	0.087	-0.643	FMNL2	formin-like 2	2	152899996	AI123567	114793	2q23.3	Hs.654630	9	actin binding cytoplasm cellular component organization Rho GTPase binding actin cytoskeleton organization
222815_at	-0.709	4.330	-4.020	1.084e-03	0.087	-0.648	RLIM	ring finger protein, LIM domain interacting	X	-73719537	BE966018	51132	Xq13-q21	Hs.653288	9	transcription corepressor activity ubiquitin-protein ligase activity protein binding zinc ion binding negative regulation of transcription ligase activity transcriptional repressor complex modification-dependent protein catabolic process metal ion binding
224906_at	-0.646	8.706	-4.020	1.084e-03	0.087	-0.648	ANO6	anoctamin 6	12	43896036, 43896036, 43896142, 43972732	AL041280	196527	12q12	Hs.696326	6	ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex
223229_at	-0.799	6.718	-4.019	1.087e-03	0.088	-0.651	UBE2T	ubiquitin-conjugating enzyme E2T (putative)	1	-200567408	AB032931	29089	1q32.1	Hs.5199	10	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
215903_s_at	-0.482	8.195	-4.018	1.089e-03	0.088	-0.652	MAST2	microtubule associated serine/threonine kinase 2	1	46041871	BE786598	23139	1p34.1	Hs.319481	19	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoskeleton plasma membrane protein amino acid phosphorylation transferase activity phosphatase binding regulation of interleukin-12 biosynthetic process spermatid differentiation
202847_at	1.315	4.676	4.015	1.097e-03	0.088	-0.658	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	14	23633322, 23633322	NM_004563	5106	14q11.2	Hs.75812	9	phosphoenolpyruvate carboxykinase (GTP) activity GTP binding mitochondrion gluconeogenesis lyase activity purine nucleotide binding manganese ion binding metal ion binding	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways PPAR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway
217835_x_at	-0.784	11.038	-4.015	1.097e-03	0.088	-0.659	C20orf24	chromosome 20 open reading frame 24	20	34667580, 34667605	NM_018840	55969	20q11.23	Hs.584985	7	molecular_function protein binding cellular_component biological_process
213327_s_at	-0.594	6.620	-4.014	1.097e-03	0.088	-0.659	USP12	ubiquitin specific peptidase 12	13	-26540437	AI820101	219333	13q12.13	Hs.42400	6	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding cellular_component protein modification process ubiquitin-dependent protein catabolic process peptidase activity protein deubiquitination
202056_at	-0.887	8.604	-4.014	1.099e-03	0.088	-0.660	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	AW051311	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
205383_s_at	-0.529	8.745	-4.012	1.102e-03	0.088	-0.663	ZBTB20	zinc finger and BTB domain containing 20	3	-115540212	NM_015642	26137	3q13.2	Hs.655108	13	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
214455_at	-1.615	3.861	-4.010	1.108e-03	0.088	-0.668	HIST1H2BC	histone cluster 1, H2bc	6	-26231673	NM_003526	8347	6p21.3	Hs.658713	10	nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly defense response to bacterium	Systemic lupus erythematosus
206356_s_at	-0.957	5.119	-4.009	1.109e-03	0.088	-0.668	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18	11679135, 11741561	NM_002071	2774	18p11.22-p11.21	Hs.136295	16	nucleotide binding GTPase activity signal transducer activity GTP binding signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding	Calcium signaling pathway Olfactory transduction
201604_s_at	-0.629	6.274	-4.008	1.111e-03	0.088	-0.671	PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	12	-78691474, -78691474, -78691474	NM_002480	4659	12q15-q21	Hs.49582	41	signal transducer activity protein binding cytoplasm	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton
214787_at	-0.607	3.839	-4.006	1.117e-03	0.088	-0.675	DENND4A	DENN/MADD domain containing 4A	15	-63740012	BE268538	10260	15q22.31	Hs.654567	8	DNA binding protein binding nucleus regulation of transcription, DNA-dependent
214663_at	-0.454	6.017	-4.005	1.118e-03	0.088	-0.676	DSTYK	dual serine/threonine and tyrosine protein kinase	1	-203378254	AB007941	25778	1q32.1	Hs.6874	9	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
227523_s_at	-0.582	6.197	-4.005	1.118e-03	0.088	-0.676	PHF20L1	PHD finger protein 20-like 1	8	133856785, 133856785, 133856785	AA192936	51105	8q24.22	Hs.304362	4	nucleic acid binding protein binding zinc ion binding metal ion binding
223294_at	-0.694	7.370	-3.997	1.136e-03	0.090	-0.691	CXorf26	chromosome X open reading frame 26	X	75309172	BC001220	51260	Xq13.3	Hs.370100	6	molecular_function cellular_component biological_process
223598_at	-0.807	9.548	-3.997	1.137e-03	0.090	-0.692	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	AF262027	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
222433_at	-1.103	8.250	-3.996	1.140e-03	0.090	-0.694	ENAH	enabled homolog (Drosophila)	1	-223741156	AK025108	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
218868_at	-0.485	5.920	-3.995	1.142e-03	0.090	-0.696	ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)	7	152087783	NM_020445	57180	7q36.1	Hs.647117	8	nucleotide binding actin binding protein binding ATP binding cytoplasm cytoskeleton regulation of actin filament polymerization cell projection
235753_at	0.787	7.886	3.994	1.144e-03	0.090	-0.698	HOXA7	homeobox A7	7	-27159862	AI492051	3204	7p15-p14	Hs.660918	24	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding negative regulation of keratinocyte differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
206289_at	0.682	6.561	3.993	1.146e-03	0.090	-0.699	HOXA4	homeobox A4	7	-27134650	NM_002141	3201	7p15-p14	Hs.533357 Hs.714774	22	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anatomical structure morphogenesis anterior/posterior pattern formation sequence-specific DNA binding embryonic skeletal system morphogenesis
203837_at	1.191	6.437	3.992	1.148e-03	0.090	-0.701	MAP3K5	mitogen-activated protein kinase kinase kinase 5	6	-136919879	NM_005923	4217	6q22.33	Hs.186486	108	MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding protein amino acid phosphorylation apoptosis activation of JUN kinase activity induction of apoptosis by extracellular signals caspase activator activity transferase activity protein homodimerization activity interspecies interaction between organisms	MAPK signaling pathway Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS)
219343_at	-1.246	8.355	-3.991	1.151e-03	0.090	-0.703	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	9	4669565	NM_017913	55664	9p24.1	Hs.561954	6	protein binding cytoplasm
226395_at	-0.950	7.792	-3.990	1.153e-03	0.090	-0.704	HOOK3	hook homolog 3 (Drosophila)	8	42871189	AI912618	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
213376_at	-0.676	6.831	-3.989	1.156e-03	0.090	-0.707	ZBTB1	zinc finger and BTB domain containing 1	14	64041044, 64041044	AI656706	22890	14q23.3	Hs.655536	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225607_at	-0.559	8.256	-3.988	1.159e-03	0.090	-0.709	CCDC43	coiled-coil domain containing 43	17	-40110330	AI948491	124808	17q21.31	Hs.579115	2
231973_s_at	-1.062	4.745	-3.986	1.164e-03	0.090	-0.713	ANAPC1	anaphase promoting complex subunit 1	2	-112243110	AK001223	64682	2q12.1	Hs.436527	26	nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
232902_s_at	-0.622	5.887	-3.982	1.172e-03	0.091	-0.720	RARS2	arginyl-tRNA synthetase 2, mitochondrial	6	-88280815	BG165118	57038	6q16.1	Hs.485910	8	nucleotide binding arginine-tRNA ligase activity protein binding ATP binding cytoplasm mitochondrion mitochondrial matrix arginyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
223422_s_at	-1.458	6.120	-3.982	1.173e-03	0.091	-0.720	ARHGAP24	Rho GTPase activating protein 24	4	86615307, 86918874, 87070449	AI743534	83478	4q21.23-q21.3	Hs.444229	14	angiogenesis GTPase activator activity protein binding intracellular cytoplasm cytoskeleton adherens junction focal adhesion signal transduction multicellular organismal development cell junction cell differentiation cell projection
201388_at	-0.521	7.184	-3.981	1.176e-03	0.091	-0.723	PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	17	35390585	NM_002809	5709	17q21.1	Hs.12970	34	proteasome complex protein binding cytosol enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
225053_at	-0.548	10.293	-3.980	1.177e-03	0.091	-0.724	CNOT7	CCR4-NOT transcription complex, subunit 7	8	-17133392, -17131110	W94952	29883	8p22-p21.3	Hs.645009 Hs.719129	19	nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter	RNA degradation
206576_s_at	0.504	6.075	3.977	1.184e-03	0.091	-0.729	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	NM_001712	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
219263_at	-0.991	6.831	-3.977	1.185e-03	0.091	-0.729	RNF128	ring finger protein 128	X	105823723, 105856549	NM_024539	79589	Xq22.3	Hs.496542	13	protein binding cytoplasm zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding perinuclear region of cytoplasm
205003_at	0.504	7.291	3.976	1.188e-03	0.091	-0.732	DOCK4	dedicator of cytokinesis 4	7	-111153399	NM_014705	9732	7q31.1	Hs.654652	16	guanyl-nucleotide exchange factor activity protein binding membrane SH3 domain binding PDZ domain binding Rac GTPase activator activity stereocilium Rac GTPase binding
212689_s_at	-0.995	6.775	-3.976	1.188e-03	0.091	-0.732	KDM3A	lysine (K)-specific demethylase 3A	2	86521781, 86522094	AA524505	55818	2p11.2	Hs.557425	11	iron ion binding nucleus cytoplasm spermatogenesis zinc ion binding hormone-mediated signaling oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cell differentiation androgen receptor signaling pathway histone H3-K9 demethylation positive regulation of transcription formaldehyde biosynthetic process metal ion binding androgen receptor binding oxidation reduction
226606_s_at	1.157	6.176	3.975	1.189e-03	0.091	-0.733	GTPBP5	GTP binding protein 5 (putative)	20	60191475	AI860690	26164	20q13.33	Hs.340636	6	nucleotide binding GTP binding intracellular mitochondrion ribosome biogenesis
201199_s_at	-0.583	9.140	-3.974	1.193e-03	0.091	-0.735	PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	2	231629852	NM_002807	5707	2q37.1	Hs.3887	43	proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
204264_at	0.933	7.437	3.972	1.197e-03	0.091	-0.739	CPT2	carnitine palmitoyltransferase 2	1	53434688	NM_000098	1376	1p32	Hs.713535	53	carnitine O-palmitoyltransferase activity carnitine O-palmitoyltransferase activity mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport carnitine shuttle acyltransferase activity membrane transferase activity regulation of fatty acid oxidation	Fatty acid metabolism PPAR signaling pathway
224298_s_at	-0.670	7.624	-3.970	1.202e-03	0.091	-0.743	UBAC2	UBA domain containing 2	13	98650679, 98651163	BC004528	337867	13q32.3	Hs.508545	6	membrane integral to membrane
225033_at	-0.641	6.709	-3.969	1.204e-03	0.091	-0.744	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	8	-134536272	AV721528	6482	8q24.22	Hs.374257	20	beta-galactoside alpha-2,3-sialyltransferase activity extracellular region Golgi apparatus protein amino acid glycosylation membrane integral to membrane integral to Golgi membrane	O-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
226230_at	-0.692	6.581	-3.967	1.208e-03	0.092	-0.747	SMEK2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	2	-55629017	AA541716	57223	2p16.1	Hs.516182	16	protein binding nucleus cytoplasm centrosome
216178_x_at	-1.199	7.325	-3.964	1.216e-03	0.092	-0.753	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	AA215854	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
205656_at	0.511	5.810	3.963	1.218e-03	0.092	-0.755	PCDH17	protocadherin 17	13	57103789	NM_014459	27253	13q21.1	Hs.106511	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
211063_s_at	-0.475	8.090	-3.963	1.219e-03	0.092	-0.755	NCK1	NCK adaptor protein 1	3	138063762	BC006403	4690	3q21	Hs.477693	110	receptor binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal complex assembly cytoskeletal adaptor activity vesicle membrane cell migration protein domain specific binding lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
210479_s_at	-1.208	6.339	-3.963	1.220e-03	0.092	-0.756	RORA	RAR-related orphan receptor A	15	-58567776, -58567776, -58567776	L14611	6095	15q22.2	Hs.560343 Hs.655155	33	transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding
202128_at	-0.653	6.577	-3.962	1.222e-03	0.092	-0.758	KIAA0317	KIAA0317	14	-74197707	NM_014821	9870	14q24.3	Hs.497417	4	intracellular protein modification process membrane integral to membrane acid-amino acid ligase activity modification-dependent protein catabolic process
205040_at	0.746	4.148	3.962	1.222e-03	0.092	-0.758	ORM1	orosomucoid 1	9	116125123	NM_000607	5004	9q31-q32	Hs.522356	55	regulation of immune system process protein binding extracellular region extracellular space acute-phase response inflammatory response
214356_s_at	-0.500	9.260	-3.960	1.226e-03	0.092	-0.761	KIAA0368	KIAA0368	9	-113162793	AI272899	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
230876_at	0.922	2.974	3.958	1.231e-03	0.092	-0.765	LOC169834	hypothetical protein LOC169834	9	-114799220	AI827906	169834	9q32	Hs.192877	1
224565_at	-0.997	10.792	-3.952	1.247e-03	0.093	-0.776	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	BE675516	283131	11q13.1	Hs.523789 Hs.648467	6
200973_s_at	-0.983	9.408	-3.952	1.247e-03	0.093	-0.776	TSPAN3	tetraspanin 3	15	-75125385	NM_005724	10099	15q24.3	Hs.5062 Hs.716484	8	membrane integral to membrane
220359_s_at	-1.864	4.646	-3.950	1.252e-03	0.094	-0.780	ARPP-21	cyclic AMP-regulated phosphoprotein, 21 kD	3	35658852, 35696119, 35697432	NM_016300	10777	3p22.3	Hs.475902 Hs.713605	7	molecular_function nucleic acid binding cellular_component cytoplasm biological_process
226632_at	0.413	6.270	3.948	1.256e-03	0.094	-0.783	CYGB	cytoglobin	17	-72035034	AL513673	114757	17q25.3	Hs.95120	28	peroxidase activity oxygen transporter activity cytoplasm transport response to oxidative stress oxygen transport oxygen binding heme binding neuron projection cell soma metal ion binding
239183_at	-1.145	6.216	-3.947	1.259e-03	0.094	-0.785	ANGPTL1	angiopoietin-like 1	1	-177085292	W67461	9068	1q25.2	Hs.591474	19	receptor binding extracellular region extracellular space signal transduction
212835_at	-1.010	6.466	-3.947	1.260e-03	0.094	-0.786	FAM175B	family with sequence similarity 175, member B	10	126480343	AA777641	23172	10q26.13	Hs.280695	10	protein binding polyubiquitin binding BRISC complex
202919_at	-0.628	8.679	-3.946	1.262e-03	0.094	-0.787	MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	2	198088564, 198089015	NM_015387	25843	2q33.1	Hs.645458	13	protein binding cytoplasm Golgi apparatus transport zinc ion binding membrane metal ion binding perinuclear region of cytoplasm
232473_at	0.609	4.405	3.942	1.274e-03	0.094	-0.796	PRPF18	PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae)	10	13668944	AU144329	8559	10p13	Hs.161181	6	nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck
201027_s_at	-0.579	7.408	-3.941	1.277e-03	0.094	-0.798	EIF5B	eukaryotic translation initiation factor 5B	2	99320265	NM_015904	9669	2q11.2	Hs.158688	15	nucleotide binding translation initiation factor activity translation initiation factor activity GTPase activity protein binding GTP binding cytoplasm translation regulation of translational initiation regulation of translational initiation
227163_at	0.528	5.026	3.940	1.278e-03	0.094	-0.799	GSTO2	glutathione S-transferase omega 2	10	106018620	AL162742	119391	10q25.1	Hs.203634	27	glutathione transferase activity cytoplasm metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
217830_s_at	-0.574	8.316	-3.937	1.286e-03	0.095	-0.805	NSFL1C	NSFL1 (p97) cofactor (p47)	20	-1370810	AL109658	55968	20p13	Hs.12865	20	protein binding nucleus Golgi apparatus Golgi stack lipid binding
201729_s_at	-0.438	7.560	-3.936	1.289e-03	0.095	-0.807	KIAA0100	KIAA0100	17	-23965584	NM_014680	9703	17q11.2	Hs.151761	5	extracellular region tricarboxylic acid cycle malate dehydrogenase (acceptor) activity
226312_at	-0.679	7.938	-3.935	1.292e-03	0.095	-0.809	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	BF940270	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
222134_at	-0.734	4.988	-3.933	1.296e-03	0.095	-0.812	DDO	D-aspartate oxidase	6	-110820075	AL050350	8528	6q21	Hs.591348	11	D-amino-acid oxidase activity binding peroxisome aspartate catabolic process D-aspartate oxidase activity oxidoreductase activity oxidation reduction	Alanine, aspartate and glutamate metabolism
226535_at	0.648	9.547	3.933	1.297e-03	0.095	-0.813	ITGB6	integrin, beta 6	2	-160666478	AK026736	3694	2q24.2	Hs.470399	44	receptor activity protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane interspecies interaction between organisms	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
226967_at	0.506	6.463	3.932	1.298e-03	0.095	-0.813	FIZ1	FLT3-interacting zinc finger 1	19	-60794548	BG231981	84922	19q13.42	Hs.515617	5	nucleic acid binding receptor binding intracellular nucleus cytoplasm zinc ion binding protein kinase binding regulation of transcription metal ion binding
201676_x_at	-0.348	10.708	-3.931	1.301e-03	0.095	-0.815	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	11	-14492087, -14482998, -14482998	NM_002786	5682	11p15.1	Hs.102798 Hs.445711	52	RNA binding threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex polysome ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
204999_s_at	2.018	5.575	3.931	1.301e-03	0.095	-0.815	ATF5	activating transcription factor 5	19	55123785	BC005174	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
212296_at	-0.529	10.020	-3.930	1.305e-03	0.095	-0.818	PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	2	161873031	NM_005805	10213	2q24.2	Hs.567410	15	proteasome complex ubiquitin thiolesterase activity protein binding cytosol ubiquitin-dependent protein catabolic process peptidase activity metallopeptidase activity zinc ion binding anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process metal ion binding negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle protein K63-linked deubiquitination	Proteasome
226029_at	0.552	4.077	3.930	1.306e-03	0.095	-0.819	VANGL2	vang-like 2 (van gogh, Drosophila)	1	158636990	AB033041	57216	1q22-q23	Hs.99477	8	establishment of planar polarity neural tube closure heart looping multicellular organismal development membrane integral to membrane sensory cilium assembly apical protein localization	Wnt signaling pathway
202724_s_at	-0.830	7.398	-3.927	1.314e-03	0.096	-0.825	FOXO1	forkhead box O1	13	-40027800	NM_002015	2308	13q14.1	Hs.370666	140	blood vessel development transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent anti-apoptosis insulin receptor signaling pathway transcription activator activity regulation of cell proliferation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter	Insulin signaling pathway Pathways in cancer Prostate cancer
218959_at	-0.608	7.426	-3.925	1.319e-03	0.096	-0.828	HOXC10	homeobox C10	12	52665212	NM_017409	3226	12q13.3	Hs.44276	13	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation proximal/distal pattern formation cyclin-dependent protein kinase activating kinase holoenzyme complex spinal cord motor neuron cell fate specification embryonic limb morphogenesis sequence-specific DNA binding neuromuscular process
217011_at	0.505	5.787	3.924	1.322e-03	0.096	-0.830	GBX1	gastrulation brain homeobox 1	7	-150476608	L11239	2636	7q36	Hs.647114	4	nuclear chromosome transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
235374_at	0.599	7.590	3.924	1.322e-03	0.096	-0.830	MDH1	malate dehydrogenase 1, NAD (soluble)	2	63669625	AW952547	4190	2p13.3	Hs.526521	18	malic enzyme activity binding soluble fraction cytoplasm cytosol cytosol glycolysis tricarboxylic acid cycle oxaloacetate metabolic process malate metabolic process oxidoreductase activity NAD metabolic process L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
218527_at	-0.394	6.301	-3.924	1.322e-03	0.096	-0.830	APTX	aprataxin	9	-32962607, -32962607, -32962607, -32962607, -32962607	NM_017692	54840	9p13.3	Hs.20158	41	single strand break repair chromatin chromatin binding damaged DNA binding double-stranded DNA binding double-stranded RNA binding intracellular nucleus nucleoplasm nucleolus response to DNA damage stimulus cell death zinc ion binding phosphoglycolate phosphatase activity hydrolase activity regulation of protein stability DNA 5'-adenosine monophosphate hydrolase activity response to hydrogen peroxide metal ion binding protein N-terminus binding
1555310_a_at	0.536	5.885	3.923	1.323e-03	0.096	-0.831	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	15	38296920, 38319326	BC035596	56924	15q14	Hs.513645	13	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
225028_at	-0.677	3.030	-3.922	1.326e-03	0.096	-0.833	LOC550643	hypothetical LOC550643	X	56772442	AI417268	550643	Xp11.1	Hs.355559	1
227476_at	-0.655	6.861	-3.920	1.331e-03	0.096	-0.836	LPGAT1	lysophosphatidylglycerol acyltransferase 1	1	-209983422	AW576195	9926	1q32	Hs.497674	6	molecular_function cytoplasm endoplasmic reticulum metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
225326_at	-0.485	7.474	-3.920	1.331e-03	0.096	-0.837	RBM27	RNA binding motif protein 27	5	145563355	AB037732	54439	5q32	Hs.61441	8	nucleotide binding RNA binding nucleus cytoplasm zinc ion binding nuclear speck metal ion binding
223104_at	-0.389	7.874	-3.919	1.336e-03	0.096	-0.839	JAGN1	jagunal homolog 1 (Drosophila)	3	9907270	AF212230	84522	3p25.2	Hs.24054	6	endoplasmic reticulum membrane integral to membrane
212337_at	-0.499	6.380	-3.918	1.337e-03	0.096	-0.840	TUG1	taurine upregulated 1 (non-protein coding)	22	29695633	AI687738	55000	22q12.2	Hs.554829	7
207233_s_at	-0.574	8.486	-3.918	1.337e-03	0.096	-0.841	MITF	microphthalmia-associated transcription factor	3	69871322, 69895651, 69998131, 70010945, 70068442	NM_000248	4286	3p14.2-p14.1	Hs.166017 Hs.618266	93	DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation	Melanogenesis Pathways in cancer Melanoma
1552309_a_at	-0.573	12.027	-3.918	1.337e-03	0.096	-0.841	NEXN	nexilin (F actin binding protein)	1	78126787	NM_144573	91624	1p31.1	Hs.612385	6	cytoplasm cytoskeleton cell-substrate adherens junction cell junction regulation of cell migration actin filament binding regulation of cytoskeleton organization
235348_at	-0.724	4.294	-3.914	1.347e-03	0.096	-0.847	ABHD13	abhydrolase domain containing 13	13	107668763	AA404347	84945	13q33.3	Hs.183528	6	membrane integral to membrane hydrolase activity
208562_s_at	-0.518	4.642	-3.914	1.350e-03	0.096	-0.849	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	12	-21849374, -21841590	NM_020297	10060	12p12.1	Hs.446050	35	nucleotide binding receptor activity transporter activity ATP binding transport sulfonylurea receptor activity ATP-sensitive potassium channel complex potassium ion import potassium channel regulator activity membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances defense response to virus	ABC transporters
212573_at	-0.728	8.451	-3.911	1.356e-03	0.097	-0.854	ENDOD1	endonuclease domain containing 1	11	94462664	AF131747	23052	11q21	Hs.167115	6	nucleic acid binding endonuclease activity extracellular region hydrolase activity metal ion binding	Apoptosis
217811_at	-0.502	8.433	-3.904	1.377e-03	0.098	-0.868	SELT	selenoprotein T	3	151803755	NM_016275	51714	3q25.1	Hs.369052	9	selenocysteine incorporation selenium binding cell redox homeostasis
200769_s_at	-0.811	6.068	-3.903	1.378e-03	0.098	-0.868	MAT2A	methionine adenosyltransferase II, alpha	2	85619798	NM_005911	4144	2p11.2	Hs.516157	18	nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
220478_at	0.413	5.601	3.902	1.383e-03	0.098	-0.871	APOL5	apolipoprotein L, 5	22	34443864	NM_030642	80831	22q12.3	Hs.326561	3	protein binding extracellular region cytoplasm lipid metabolic process lipid transport high-density lipoprotein binding lipid binding lipoprotein metabolic process
205105_at	-0.781	6.980	-3.899	1.391e-03	0.099	-0.877	MAN2A1	mannosidase, alpha, class 2A, member 1	5	109053054	NM_002372	4124	5q21-q22	Hs.432822	29	Golgi membrane in utero embryonic development liver development alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing mitochondrion organization vacuole organization respiratory gaseous exchange metabolic process zinc ion binding membrane integral to membrane hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding lung alveolus development	N-Glycan biosynthesis Metabolic pathways
225601_at	-0.968	5.667	-3.898	1.394e-03	0.099	-0.879	HMGB3	high-mobility group box 3	X	149902420	AI806853	3149	Xq28	Hs.19114	11	nucleus chromosome multicellular organismal development DNA bending activity negative regulation of B cell differentiation negative regulation of myeloid cell differentiation
218013_x_at	-0.932	6.579	-3.897	1.397e-03	0.099	-0.880	DCTN4	dynactin 4 (p62)	5	-150068502, -150068502	NM_016221	51164	5q31-q32	Hs.675564	7	nucleus cytoplasm centrosome cytoskeleton protein N-terminus binding	Huntington's disease
214992_s_at	-0.771	5.483	-3.897	1.397e-03	0.099	-0.881	DNASE2	deoxyribonuclease II, lysosomal	19	-12847024	AD000092	1777	19p13.2	Hs.118243	27	DNA binding endodeoxyribonuclease activity deoxyribonuclease II activity protein binding lysosome DNA catabolic process apoptosis multicellular organismal development hydrolase activity erythrocyte differentiation	Lysosome
205007_s_at	0.931	6.177	3.895	1.401e-03	0.099	-0.883	CIB2	calcium and integrin binding family member 2	15	-76184045	AI478592	10518	15q24	Hs.129867	6	calcium ion binding protein binding
202582_s_at	-0.558	9.914	-3.894	1.404e-03	0.099	-0.885	RANBP9	RAN binding protein 9	6	-13729708	AF306510	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
201857_at	-0.439	9.409	-3.893	1.407e-03	0.099	-0.887	ZFR	zinc finger RNA binding protein	5	-32390212	NM_016107	51663	5p13.3	Hs.435231	6	DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding
223880_x_at	-0.793	10.902	-3.889	1.419e-03	0.099	-0.895	C20orf24	chromosome 20 open reading frame 24	20	34667580, 34667605	BC004446	55969	20q11.23	Hs.584985	7	molecular_function protein binding cellular_component biological_process
226317_at	-0.800	6.772	-3.889	1.421e-03	0.099	-0.896	PPP4R2	protein phosphatase 4, regulatory subunit 2	3	73128808	AI983837	151987	3p13	Hs.431092	7	protein binding centrosome mRNA processing protein modification process RNA splicing
243409_at	0.375	5.675	3.888	1.422e-03	0.099	-0.897	FOXL1	forkhead box L1	16	85169615	AI005407	2300	16q24	Hs.533830	7	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development DNA bending activity sequence-specific DNA binding
202303_x_at	-0.713	5.846	-3.888	1.424e-03	0.099	-0.898	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	NM_003601	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
244353_s_at	0.749	6.558	3.887	1.426e-03	0.099	-0.900	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12	6	-134350411	AI675682	154091	6q23.2	Hs.486508	11	transporter activity cytoplasm carbohydrate transport membrane integral to membrane substrate-specific transmembrane transporter activity perinuclear region of cytoplasm transmembrane transport
239297_at	0.462	4.095	3.885	1.431e-03	0.100	-0.903	C8orf79	chromosome 8 open reading frame 79	8	12847553, 12914143	BE932011	57604	8p22	Hs.202521	5	metabolic process methyltransferase activity transferase activity
1553039_a_at	0.373	7.101	3.884	1.433e-03	0.100	-0.904	ASB10	ankyrin repeat and SOCS box-containing 10	7	-150503717, -150503717	NM_080871	136371	7q36.1	Hs.647081	6	intracellular signaling cascade modification-dependent protein catabolic process
218181_s_at	-0.588	6.902	-3.884	1.433e-03	0.100	-0.904	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	2	101680919	NM_017792	9448	2q11.2-q12	Hs.719073	22	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade transferase activity	MAPK signaling pathway
219449_s_at	-1.226	10.923	-3.884	1.434e-03	0.100	-0.905	TMEM70	transmembrane protein 70	8	75050983	NM_017866	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
227542_at	-0.803	7.379	-3.883	1.437e-03	0.100	-0.907	SOCS6	suppressor of cytokine signaling 6	18	66107116	AU157543	9306	18q22.2	Hs.44439	13	protein binding cytoplasm defense response intracellular signaling cascade JAK-STAT cascade negative regulation of signal transduction modification-dependent protein catabolic process regulation of growth
201586_s_at	-0.436	7.590	-3.882	1.440e-03	0.100	-0.908	SFPQ	splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)	1	-35421789	NM_005066	6421	1p34.3	Hs.355934	47	nucleotide binding DNA binding RNA binding protein binding nucleus DNA repair DNA recombination mRNA processing response to DNA damage stimulus RNA splicing nuclear matrix regulation of transcription
227696_at	0.979	8.541	3.881	1.443e-03	0.100	-0.911	EXOSC6	exosome component 6	16	-68841634	AI701408	118460	16q22.1	Hs.660633 Hs.719211	9	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
214030_at	-0.463	7.447	-3.880	1.444e-03	0.100	-0.911	CRYBG3	beta-gamma crystallin domain containing 3	3	99078508	BE501352	131544	3q11.2	Hs.714457	2	sugar binding
226968_at	-0.699	10.187	-3.880	1.447e-03	0.100	-0.913	KIF1B	kinesin family member 1B	1	10193350, 10193350	AK023184	23095	1p36.2	Hs.97858	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle
206383_s_at	-0.742	5.206	-3.879	1.449e-03	0.100	-0.915	G3BP2	GTPase activating protein (SH3 domain) binding protein 2	4	-76786976, -76786976	NM_012297	9908	4q21.1	Hs.303676	15	nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport
231358_at	0.543	5.244	3.878	1.451e-03	0.100	-0.915	MRO	maestro	18	-46575487, -46575487	BE465760	83876	18q21	Hs.30495	6	binding nucleus nucleolus
218694_at	-0.780	8.432	-3.877	1.454e-03	0.100	-0.918	ARMCX1	armadillo repeat containing, X-linked 1	X	100692169	NM_016608	51309	Xq21.33-q22.2	Hs.9728	8	binding membrane integral to membrane
206342_x_at	-0.663	6.047	-3.876	1.456e-03	0.100	-0.919	IDS	iduronate 2-sulfatase	X	-148376566, -148368202	NM_006123	3423	Xq28	Hs.460960	73	iduronate-2-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
216779_at	0.314	3.685	3.874	1.465e-03	0.100	-0.924	CYLC1	cylicin, basic protein of sperm head cytoskeleton 1	X	83002825	Z22780	1538	Xq21.1	Hs.444230	6	structural molecule activity cytoplasm cytoskeleton multicellular organismal development spermatogenesis cell differentiation cytoskeletal calyx acrosomal matrix
214846_s_at	-0.994	7.757	-3.870	1.475e-03	0.101	-0.931	ALPK3	alpha-kinase 3	15	83160914	AB037751	57538	15q25.2	Hs.459183	5	protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation multicellular organismal development heart development kinase activity transferase activity
213380_x_at	0.475	5.443	3.870	1.477e-03	0.101	-0.932	MSTP9	macrophage stimulating, pseudogene 9	1	-16953988	AA911235	11223	1p36.13	Hs.349110 Hs.655432	2	serine-type endopeptidase activity extracellular region proteolysis peptidase activity
1563842_at	0.330	4.922	3.867	1.485e-03	0.101	-0.937	PIGG	phosphatidylinositol glycan anchor biosynthesis, class G	4	482988	AK097244	54872	4p16.3	Hs.7099	8	protein binding endoplasmic reticulum endoplasmic reticulum membrane metabolic process membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity phosphotransferase activity, for other substituted phosphate groups CP2 mannose-ethanolamine phosphotransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
227091_at	0.463	4.776	3.865	1.491e-03	0.101	-0.941	CCDC146	coiled-coil domain containing 146	7	76589869	AB040938	57639	7q11.23	Hs.113940	4
235595_at	0.492	6.625	3.864	1.496e-03	0.101	-0.943	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	1	-154183253, -154183253	AW299534	9181	1q21-q22	Hs.655209	28	cell morphogenesis guanyl-nucleotide exchange factor activity intracellular cytoplasm Golgi apparatus spindle microtubule tight junction intracellular protein transport actin filament organization negative regulation of microtubule depolymerization cell cycle mitosis intracellular signaling cascade microtubule binding zinc ion binding diacylglycerol binding cell junction Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction regulation of cell proliferation metal ion binding Rac GTPase binding cell division	Pathogenic Escherichia coli infection - EHEC
225363_at	-0.388	8.593	-3.863	1.496e-03	0.101	-0.944	PTEN	phosphatase and tensin homolog	10	89613174	AK024986	5728	10q23.3	Hs.500466	557	regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade	Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer
205499_at	-0.559	4.423	-3.859	1.510e-03	0.102	-0.952	SRPX2	sushi-repeat-containing protein, X-linked 2	X	99785818	NM_014467	27286	Xq21.33-q23	Hs.306339	13	extracellular region
212468_at	-0.821	6.974	-3.858	1.512e-03	0.102	-0.953	SPAG9	sperm associated antigen 9	17	-46394534	AK023512	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
234947_s_at	-0.698	7.166	-3.858	1.514e-03	0.102	-0.955	C10orf84	chromosome 10 open reading frame 84	10	-120058561	AK026630	63877	10q26.11	Hs.372309	5
225032_at	-0.709	8.203	-3.857	1.516e-03	0.102	-0.956	FNDC3B	fibronectin type III domain containing 3B	3	173240111, 173241037	AI141784	64778	3q26.31	Hs.159430	9	endoplasmic reticulum membrane integral to membrane
210072_at	0.394	3.942	3.857	1.517e-03	0.102	-0.956	CCL19	chemokine (C-C motif) ligand 19	9	-34679566	U88321	6363	9p13	Hs.50002	39	extracellular region extracellular space cellular calcium ion homeostasis chemotaxis inflammatory response immune response signal transduction chemokine activity response to virus	Cytokine-cytokine receptor interaction Chemokine signaling pathway
212590_at	-0.848	7.834	-3.856	1.519e-03	0.102	-0.958	RRAS2	related RAS viral (r-ras) oncogene homolog 2	11	-14256041, -14256041	AI431643	22800	11p15.2	Hs.502004	25	nucleotide binding GTPase activity protein binding GTP binding intracellular endoplasmic reticulum plasma membrane Ras protein signal transduction cellular process positive regulation of cell migration	MAPK signaling pathway Tight junction Regulation of actin cytoskeleton
221667_s_at	-0.839	11.262	-3.855	1.523e-03	0.102	-0.960	HSPB8	heat shock 22kDa protein 8	12	118100977	AF133207	26353	12q24.23	Hs.400095	48	protein serine/threonine kinase activity cellular_component intracellular biological_process cell death response to heat identical protein binding
1555259_at	-0.755	5.978	-3.854	1.526e-03	0.102	-0.962	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AF465843	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
202077_at	0.453	12.059	3.852	1.531e-03	0.102	-0.965	NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	16	-23499835	NM_005003	4706	16p12.2	Hs.189716	14	acyl carrier activity fatty acid binding calcium ion binding mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone fatty acid biosynthetic process transport NADH dehydrogenase (ubiquinone) activity electron transport chain phosphopantetheine binding mitochondrial membrane mitochondrial membrane cofactor binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
201936_s_at	-1.123	7.459	-3.852	1.531e-03	0.102	-0.965	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	1	-21005560	NM_003760	8672	1p36.12	Hs.467084	19	RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
40255_at	-0.430	6.337	-3.851	1.535e-03	0.102	-0.967	DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	16	-66612674	AC004531	55794	16q22.1	Hs.458313	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mitochondrion ATP-dependent helicase activity hydrolase activity mitochondrial nucleoid
232913_at	0.387	5.067	3.848	1.544e-03	0.102	-0.973	TMED8	transmembrane emp24 protein transport domain containing 8	14	-76877866	AC007954	283578	14q24.3	Hs.200413 Hs.26403	6
209025_s_at	-0.728	7.549	-3.848	1.544e-03	0.102	-0.973	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	AF037448	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
202211_at	-0.577	6.940	-3.847	1.547e-03	0.102	-0.974	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	22	-41522475	BC005122	26286	22q13.2-q13.3	Hs.162877	15	cytoplasm Golgi apparatus cytosol intracellular protein transport ARF GTPase activator activity zinc ion binding protein transporter activity protein secretion membrane vesicle-mediated transport regulation of ARF GTPase activity metal ion binding	Endocytosis
205621_at	-0.465	6.865	-3.846	1.551e-03	0.103	-0.977	ALKBH1	alkB, alkylation repair homolog 1 (E. coli)	14	-77208501	NM_006020	8846	14q24.3	Hs.94542	6	DNA dealkylation
223046_at	-0.695	10.533	-3.845	1.554e-03	0.103	-0.979	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	AL117352	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
210257_x_at	-0.584	4.790	-3.840	1.571e-03	0.103	-0.988	CUL4B	cullin 4B	X	-119542473, -119542473	AF212995	8450	Xq23	Hs.102914	28	molecular_function protein binding cellular_component DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
202370_s_at	-0.643	7.815	-3.838	1.575e-03	0.103	-0.991	CBFB	core-binding factor, beta subunit	16	65620550	NM_001755	865	16q22.1	Hs.460988	39	osteoblast differentiation transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus lymphocyte differentiation myeloid cell differentiation positive regulation of transcription from RNA polymerase II promoter cell maturation definitive hemopoiesis
209027_s_at	-0.719	5.959	-3.838	1.576e-03	0.103	-0.991	ABI1	abl-interactor 1	10	-27075530	BF673013	10006	10p11.2	Hs.508148	39	intracellular soluble fraction nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal protein binding negative regulation of cell proliferation peptidyl-tyrosine phosphorylation synaptosome lamellipodium cell junction filopodium growth cone synapse
225525_at	-1.547	7.458	-3.838	1.576e-03	0.103	-0.992	KIAA1671	KIAA1671	22	23753940	AB051458	85379	22q11.23	Hs.419171	4
203264_s_at	0.591	5.026	3.838	1.577e-03	0.103	-0.992	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9	X	-62771572	NM_015185	23229	Xq11.1	Hs.54697	10	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm regulation of Rho protein signal transduction
235103_at	-0.956	6.297	-3.835	1.586e-03	0.104	-0.997	MAN2A1	mannosidase, alpha, class 2A, member 1	5	109053054	AA029155	4124	5q21-q22	Hs.432822	29	Golgi membrane in utero embryonic development liver development alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing mitochondrion organization vacuole organization respiratory gaseous exchange metabolic process zinc ion binding membrane integral to membrane hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding lung alveolus development	N-Glycan biosynthesis Metabolic pathways
210407_at	-0.852	5.498	-3.834	1.588e-03	0.104	-0.999	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AF070670	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
220949_s_at	-0.562	7.049	-3.834	1.589e-03	0.104	-0.999	C7orf49	chromosome 7 open reading frame 49	7	-134501071	NM_024033	78996	7q33	Hs.521213	4	cytoplasm
222668_at	-1.123	4.264	-3.834	1.590e-03	0.104	-1.000	KCTD15	potassium channel tetramerisation domain containing 15	19	38979590	W73820	79047	19q13.11	Hs.221873 Hs.606506	12	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
212585_at	-0.789	7.101	-3.832	1.596e-03	0.104	-1.003	OSBPL8	oxysterol binding protein-like 8	12	-75269708	BF970829	114882	12q14	Hs.430849	13	lipid transport steroid metabolic process
207643_s_at	-0.512	6.990	-3.831	1.600e-03	0.104	-1.006	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	12	-6308183	NM_001065	7132	12p13.2	Hs.279594 Hs.713833	271	receptor activity tumor necrosis factor receptor activity protein binding extracellular region plasma membrane plasma membrane integral to plasma membrane prostaglandin metabolic process apoptosis signal transduction cytokine-mediated signaling pathway positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms membrane raft positive regulation of transcription from RNA polymerase II promoter positive regulation of inflammatory response	MAPK signaling pathway Cytokine-cytokine receptor interaction Apoptosis Adipocytokine signaling pathway Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
217878_s_at	-0.971	7.117	-3.829	1.606e-03	0.104	-1.009	CDC27	cell division cycle 27 homolog (S. cerevisiae)	17	-42550309	AI203880	996	17q12-q23.2	Hs.463295	53	protein binding nucleus nucleoplasm cytoplasm centrosome cytosol spindle microtubule mitotic metaphase/anaphase transition cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
217403_s_at	-0.469	3.202	-3.828	1.608e-03	0.104	-1.010	ZNF227	zinc finger protein 227	19	49408530	AC074331	7770		Hs.371335	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
230708_at	0.439	4.821	3.827	1.612e-03	0.104	-1.013	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	AA206141	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
202009_at	-0.472	8.592	-3.825	1.620e-03	0.105	-1.017	TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	3	-52237665	NM_007284	11344	3p21.1	Hs.436439	9	actin binding protein binding ATP binding intracellular cytoplasm cytoskeleton perinuclear region of cytoplasm
221889_at	0.450	4.909	3.825	1.620e-03	0.105	-1.017	KCTD13	potassium channel tetramerisation domain containing 13	16	-29825161	AW026481	253980	16p11.2	Hs.534590	9	voltage-gated potassium channel activity nucleus DNA replication potassium ion transport voltage-gated potassium channel complex membrane identical protein binding
203411_s_at	-0.419	7.886	-3.824	1.621e-03	0.105	-1.017	LMNA	lamin A/C	1	154351084, 154351084	NM_005572	4000	1q21.2-q21.3	Hs.594444	279	structural molecule activity protein binding nucleus cytoplasm intermediate filament plasma membrane	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212271_at	-0.551	7.929	-3.823	1.624e-03	0.105	-1.019	MAPK1	mitogen-activated protein kinase 1	22	-20453318, -20443946	AA195999	5594	22q11.2 22q11.21	Hs.431850	822	MAPKKK cascade nucleotide binding phosphotyrosine binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol cytoskeleton protein amino acid phosphorylation induction of apoptosis chemotaxis response to DNA damage stimulus cell cycle Ras protein signal transduction synaptic transmission organ morphogenesis transferase activity MAP kinase 2 activity cytosine metabolic process lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to exogenous dsRNA interspecies interaction between organisms negative regulation of cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation TGF-beta signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Type II diabetes mellitus Alzheimer's disease Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
212328_at	-0.623	9.315	-3.822	1.630e-03	0.105	-1.023	LIMCH1	LIM and calponin homology domains 1	4	41057560, 41309675	AB029025	22998	4p13	Hs.335163	10	actin binding zinc ion binding actomyosin structure organization metal ion binding
221821_s_at	-0.985	7.843	-3.821	1.632e-03	0.105	-1.023	C12orf41	chromosome 12 open reading frame 41	12	-47333261	AK022732	54934	12q13.11	Hs.505412	8
226137_at	-0.711	7.435	-3.821	1.632e-03	0.105	-1.024	ZFHX3	zinc finger homeobox 3	16	-71374286	AI288759	463	16q22.3-q23.1	Hs.598297	26	negative regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor activity, enhancer binding intracellular nucleus transcription factor complex mitochondrion regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity sequence-specific DNA binding metal ion binding
205841_at	-1.034	5.502	-3.820	1.636e-03	0.105	-1.026	JAK2	Janus kinase 2	9	4975244	NM_004972	3717	9p24	Hs.656213	588	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding ATP binding nucleus cytoplasm cytoskeleton caveola apoptosis cell motion enzyme linked receptor protein signaling pathway tyrosine phosphorylation of STAT protein STAT protein nuclear translocation mesoderm development negative regulation of cell proliferation positive regulation of phosphoinositide 3-kinase cascade membrane transferase activity myeloid cell differentiation SH2 domain binding positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of DNA binding response to antibiotic positive regulation of peptidyl-tyrosine phosphorylation JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway	Chemokine signaling pathway Jak-STAT signaling pathway Adipocytokine signaling pathway
220757_s_at	-0.570	6.926	-3.817	1.645e-03	0.105	-1.031	UBXN6	UBX domain protein 6	19	-4396260	NM_025241	80700	19p13	Hs.435255 Hs.661664	6	molecular_function protein binding cellular_component nucleus cytoplasm centrosome biological_process modification-dependent protein catabolic process
200684_s_at	-0.687	6.645	-3.817	1.647e-03	0.105	-1.032	UBE2L3	ubiquitin-conjugating enzyme E2L 3	22	20251956	AI819709	7332	22q11.21	Hs.108104 Hs.603229 Hs.715088	38	ubiquitin ligase complex nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity enzyme binding regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
226567_at	-0.648	8.468	-3.816	1.649e-03	0.105	-1.033	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	18	148482	BG283995	9097	18p11.32	Hs.464416 Hs.707058	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity
223886_s_at	-0.406	9.888	-3.815	1.652e-03	0.105	-1.035	RNF146	ring finger protein 146	6	127629712	AL136829	81847	6q22.1-q22.33	Hs.267120	12	protein binding zinc ion binding metal ion binding
237094_at	-0.545	2.970	-3.815	1.652e-03	0.105	-1.035	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	22	47263951, 47350781	AI953086	25817	22q13.32	Hs.436854 Hs.632788	8	extracellular region membrane integral to membrane
220565_at	0.804	4.568	3.815	1.654e-03	0.105	-1.036	CCR10	chemokine (C-C motif) receptor 10	17	-38084945	NM_016602	2826	17q21.1-q21.3	Hs.719562	20	receptor activity G-protein coupled receptor activity protein binding plasma membrane integral to plasma membrane chemotaxis signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration C-C chemokine receptor activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
231935_at	-1.033	7.696	-3.814	1.658e-03	0.105	-1.038	ARPP-21	cyclic AMP-regulated phosphoprotein, 21 kD	3	35658852, 35696119, 35697432	AL133109	10777	3p22.3	Hs.475902 Hs.713605	7	molecular_function nucleic acid binding cellular_component cytoplasm biological_process
225131_at	-0.803	7.856	-3.813	1.661e-03	0.105	-1.040	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	H60265	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
201243_s_at	-0.629	11.157	-3.811	1.667e-03	0.105	-1.043	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	1	167342570	NM_001677	481	1q24	Hs.291196	34	response to hypoxia sodium:potassium-exchanging ATPase activity protein binding plasma membrane sodium:potassium-exchanging ATPase complex ATP biosynthetic process ion transport potassium ion transport sodium ion transport integral to membrane basolateral plasma membrane potassium ion binding sodium ion binding	Cardiac muscle contraction
213859_x_at	-0.564	3.540	-3.809	1.672e-03	0.105	-1.046	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	AI652586	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
222568_at	-0.454	6.088	-3.809	1.673e-03	0.105	-1.047	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1	2	128565223, 128565251	AI672492	56886	2q14.3	Hs.598715 Hs.719174	10	UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding
211537_x_at	-0.664	5.912	-3.805	1.686e-03	0.106	-1.053	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AF218074	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
207327_at	-0.477	5.525	-3.805	1.687e-03	0.106	-1.054	EYA4	eyes absent homolog 4 (Drosophila)	6	133604187	NM_004100	2070	6q23	Hs.596680	15	magnesium ion binding protein tyrosine phosphatase activity nucleus cytoplasm DNA repair response to DNA damage stimulus multicellular organismal development visual perception metabolic process anatomical structure morphogenesis chromatin modification hydrolase activity regulation of transcription
36554_at	-0.693	5.830	-3.804	1.691e-03	0.106	-1.056	ASMTL	acetylserotonin O-methyltransferase-like	X, Y	-1482031, -1482031	Y15521	8623	Xp22.3 Yp11.3	Hs.533514	10	cellular_component cytoplasm acetylserotonin O-methyltransferase activity melatonin biosynthetic process
209860_s_at	-0.696	9.710	-3.802	1.697e-03	0.106	-1.059	ANXA7	annexin A7	10	-74805194	J04543	310	10q21.1-q21.2	Hs.631827	24	calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding
230249_at	-1.443	5.937	-3.802	1.698e-03	0.106	-1.060	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	8	136538897	AI650382	10656	8q24.2	Hs.444558	20	RNA binding protein binding nucleus nucleolus cytoplasm spermatogenesis SH3 domain binding regulation of transcription
1553102_a_at	-0.721	8.649	-3.802	1.698e-03	0.106	-1.060	CCDC69	coiled-coil domain containing 69	5	-150540805	BC016647	26112	5q33.1	Hs.655336	3
1552734_at	-0.382	3.951	-3.801	1.699e-03	0.106	-1.061	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	NM_152756	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
224636_at	-0.664	8.964	-3.801	1.700e-03	0.106	-1.061	ZFP91	zinc finger protein 91 homolog (mouse)	11	58103162	AL045405	80829	11q12	Hs.524920	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
224476_s_at	0.574	7.217	3.801	1.702e-03	0.106	-1.062	MESP1	mesoderm posterior 1 homolog (mouse)	15	-88094103	BC006219	55897	15q26.1	Hs.447531	4	heart morphogenesis DNA binding nucleus Notch signaling pathway multicellular organismal development mesodermal cell migration transcription regulator activity regulation of transcription
208643_s_at	-0.536	8.176	-3.798	1.713e-03	0.106	-1.068	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	2	216682264	J04977	7520	2q35	Hs.388739	148	nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding promoter binding hydrolase activity provirus integration initiation of viral infection	Non-homologous end-joining
1558762_a_at	0.418	5.053	3.797	1.716e-03	0.106	-1.069	ZNF789	zinc finger protein 789	7	98908450, 98908450	AK093141	285989	7q22.1	Hs.440384	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211597_s_at	0.671	7.451	3.794	1.726e-03	0.107	-1.075	HOPX	HOP homeobox	4	-57208910, -57208910	AB059408	84525	4q11-q12	Hs.654864	25	negative regulation of transcription from RNA polymerase II promoter trophectodermal cell differentiation transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development heart development regulation of heart contraction transcription repressor activity histone deacetylation positive regulation of skeletal muscle regeneration sequence-specific DNA binding negative regulation of cell differentiation lung alveolus development positive regulation of striated muscle cell differentiation
55662_at	-0.599	6.188	-3.793	1.729e-03	0.107	-1.077	C10orf76	chromosome 10 open reading frame 76	10	-103595345	H27225	79591	10q24.32	Hs.16004	4	membrane integral to membrane
208985_s_at	-0.839	9.651	-3.793	1.730e-03	0.107	-1.077	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	BC002719	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
211968_s_at	-0.774	9.335	-3.793	1.730e-03	0.107	-1.077	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	AI962933	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
216251_s_at	-0.388	6.200	-3.792	1.733e-03	0.107	-1.079	TTLL12	tubulin tyrosine ligase-like family, member 12	22	-41892571	BF965437	23170	22q13.31	Hs.517670	6	tubulin-tyrosine ligase activity protein modification process
226548_at	0.527	7.623	3.791	1.736e-03	0.107	-1.081	SBK1	SH3-binding domain kinase 1	16	28211340	AI935915	388228	16p11.2	Hs.97837	3	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
224961_at	-0.488	6.565	-3.789	1.743e-03	0.107	-1.084	SCYL2	SCY1-like 2 (S. cerevisiae)	12	99185679	AB037781	55681	12q23.1	Hs.506481	8	protein kinase activity binding ATP binding cytoplasm endosome Golgi apparatus protein amino acid phosphorylation endosome membrane membrane clathrin-coated vesicle cytoplasmic vesicle perinuclear region of cytoplasm
218869_at	1.022	8.408	3.789	1.744e-03	0.107	-1.084	MLYCD	malonyl-CoA decarboxylase	16	82490230	NM_012213	23417	16q24	Hs.644610	16	methylmalonyl-CoA decarboxylase activity cytoplasm mitochondrion peroxisome cytosol acetyl-CoA biosynthetic process fatty acid biosynthetic process acyl-CoA metabolic process lyase activity regulation of fatty acid beta-oxidation malonyl-CoA decarboxylase activity	beta-Alanine metabolism Propanoate metabolism Metabolic pathways
200882_s_at	-0.516	9.443	-3.786	1.754e-03	0.107	-1.090	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	NM_002810	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
212036_s_at	-0.613	7.762	-3.783	1.763e-03	0.108	-1.095	PNN	pinin, desmosome associated protein	14	38714137	AW152664	5411	14q21.1	Hs.409965	30	DNA binding structural molecule activity protein binding nucleus spliceosomal complex nucleolus cytoplasm intermediate filament plasma membrane mRNA processing cell adhesion RNA splicing nuclear speck desmosome regulation of transcription
219887_at	0.319	4.457	3.782	1.767e-03	0.108	-1.097	CCDC87	coiled-coil domain containing 87	11	-66114215	NM_018219	55231	11q13.2	Hs.121072	3
226736_at	-2.502	7.588	-3.781	1.772e-03	0.108	-1.099	CHURC1	churchill domain containing 1	14	64450892	BE568660	91612	14q23.3	Hs.325531	5	multicellular organismal development zinc ion binding transcription activator activity positive regulation of transcription metal ion binding
212582_at	-0.990	7.202	-3.780	1.777e-03	0.108	-1.102	OSBPL8	oxysterol binding protein-like 8	12	-75269708	AL049923	114882	12q14	Hs.430849	13	lipid transport steroid metabolic process
212717_at	-0.433	6.963	-3.774	1.798e-03	0.110	-1.113	PLEKHM1	pleckstrin homology domain containing, family M (with RUN domain) member 1	17	-40869048	AB002354	9842	17q21.31	Hs.514242	7	cytoplasm intracellular signaling cascade zinc ion binding diacylglycerol binding metal ion binding
201174_s_at	-0.413	8.264	-3.773	1.800e-03	0.110	-1.114	TERF2IP	telomeric repeat binding factor 2, interacting protein	16	74239184	NM_018975	54386	16q23.1	Hs.301419	25	nuclear chromosome nuclear telomere cap complex DNA binding protein binding nucleus nucleoplasm cytoplasm telomere maintenance via telomerase Mre11 complex protection from non-homologous end joining at telomere negative regulation of telomere maintenance telomeric DNA binding regulation of transcription protein localization to telomere
233632_s_at	-0.892	7.190	-3.773	1.801e-03	0.110	-1.114	XRN1	5'-3' exoribonuclease 1	3	-143508138	AL117516	54464	3q23	Hs.435103	12	DNA binding RNA binding protein binding intracellular cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5'-3' exonuclease activity hydrolase activity	RNA degradation
201856_s_at	-0.797	5.459	-3.773	1.803e-03	0.110	-1.115	ZFR	zinc finger RNA binding protein	5	-32390212	BC000376	51663	5p13.3	Hs.435231	6	DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding
215286_s_at	-0.529	4.704	-3.772	1.807e-03	0.110	-1.117	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AL050389	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
212765_at	-0.546	7.042	-3.768	1.820e-03	0.110	-1.124	CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1	1	198975308	AB029001	23271	1q32.1	Hs.23585	6
212886_at	-0.576	9.167	-3.765	1.833e-03	0.111	-1.130	CCDC69	coiled-coil domain containing 69	5	-150540805	AL080169	26112	5q33.1	Hs.655336	3
205478_at	0.803	11.526	3.764	1.835e-03	0.111	-1.131	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	12	-53259290	NM_006741	5502	12q13.2	Hs.505662	9	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process signal transduction	Long-term potentiation
200816_s_at	-0.403	9.168	-3.763	1.839e-03	0.111	-1.133	PAFAH1B1	platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)	17	2443672	NM_000430	5048	17p13.3	Hs.77318	75	establishment of mitotic spindle orientation astral microtubule kinetochore acrosome assembly neuron migration nucleus cytoplasm centrosome spindle cytosol microtubule microtubule associated complex cell cortex transport cell cycle mitosis synaptic transmission multicellular organismal development nervous system development neuroblast proliferation learning or memory microtubule binding retrograde axon cargo transport heparin binding adult locomotory behavior membrane lipid catabolic process corpus callosum morphogenesis hippocampus development layer formation in the cerebral cortex cerebral cortex development actin cytoskeleton organization cell differentiation microtubule organizing center organization cell leading edge motile primary cilium nonmotile primary cilium nuclear membrane regulation of Rho GTPase activity dynactin binding protein homodimerization activity phospholipase binding dynein binding platelet activating factor metabolic process vesicle transport along microtubule perinuclear region of cytoplasm brain morphogenesis neuromuscular process controlling balance phosphoprotein binding cell division	Ether lipid metabolism Metabolic pathways
224177_s_at	-0.591	6.290	-3.763	1.841e-03	0.111	-1.134	CXorf26	chromosome X open reading frame 26	X	75309172	AF151079	51260	Xq13.3	Hs.370100	6	molecular_function cellular_component biological_process
208625_s_at	-0.577	8.464	-3.760	1.851e-03	0.111	-1.139	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	3	185515049, 185515664, 185520956	AF104913	1981	3q27-qter	Hs.433750	91	RNA binding translation initiation factor activity protein binding cytoplasm cytosol regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
205155_s_at	0.487	5.574	3.759	1.854e-03	0.112	-1.141	SPTBN2	spectrin, beta, non-erythrocytic 2	11	-66209296	NM_006946	6712	11q13	Hs.26915	18	actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton cell cortex spectrin cell death vesicle-mediated transport actin filament capping
1558689_a_at	0.347	3.184	3.758	1.860e-03	0.112	-1.144	LOC441461	hypothetical LOC441461	9		BG701300	441461	9q31.1	Hs.163155	1
1564537_a_at	0.584	6.672	3.757	1.863e-03	0.112	-1.145	ASB10	ankyrin repeat and SOCS box-containing 10	7	-150503717, -150503717	AK055536	136371	7q36.1	Hs.647081	6	intracellular signaling cascade modification-dependent protein catabolic process
228980_at	-0.901	6.188	-3.753	1.878e-03	0.112	-1.152	RFFL	ring finger and FYVE-like domain containing 1	17	-30360243, -30360243	AI760772	117584	17q12	Hs.13680	11	protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding
203588_s_at	-0.684	6.335	-3.752	1.880e-03	0.112	-1.153	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	BG034328	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
201994_at	-0.501	11.098	-3.750	1.891e-03	0.113	-1.159	MORF4L2	mortality factor 4 like 2	X	-102817083, -102817083	NM_012286	9643	Xq22	Hs.326387 Hs.441076 Hs.597035	19	regulation of cell growth molecular_function protein binding nucleus nucleolus DNA repair response to DNA damage stimulus chromatin modification regulation of transcription
208767_s_at	-1.610	9.437	-3.747	1.900e-03	0.113	-1.163	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	AW149681	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
212530_at	-0.643	9.438	-3.747	1.901e-03	0.113	-1.164	NEK7	NIMA (never in mitosis gene a)-related kinase 7	1	196392730	AL080111	140609	1q31.3	Hs.24119	7	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
232267_at	-0.707	5.050	-3.746	1.906e-03	0.113	-1.166	GPR133	G protein-coupled receptor 133	12	130004404	AL162032	283383	12q24.33	Hs.719239	7	G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
226180_at	-0.880	6.777	-3.745	1.909e-03	0.113	-1.168	WDR36	WD repeat domain 36	5	110455768	BF439595	134430	5q22.1	Hs.533237	19	molecular_function cellular_component rRNA processing visual perception small-subunit processome response to stimulus
220617_s_at	-0.482	8.309	-3.744	1.911e-03	0.113	-1.168	ZNF532	zinc finger protein 532	18	54681040	NM_018181	55205	18q21.32	Hs.529023 Hs.607676	4	DNA binding intracellular nucleus nucleolus Golgi apparatus zinc ion binding regulation of transcription metal ion binding
224149_x_at	-0.889	6.677	-3.744	1.912e-03	0.113	-1.169	SLMAP	sarcolemma associated protein	3	57718213	AF304450	7871	3p21.2-p14.3	Hs.476432	11	smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding
1553678_a_at	-0.726	8.235	-3.744	1.912e-03	0.113	-1.169	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	NM_133376	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
200878_at	0.562	10.038	3.744	1.913e-03	0.113	-1.169	EPAS1	endothelial PAS domain protein 1	2	46378066	AF052094	2034	2p21-p16	Hs.468410	101	angiogenesis response to hypoxia embryonic placenta development blood vessel remodeling regulation of heart rate RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus transcription factor complex transcription factor complex cytoplasm regulation of transcription, DNA-dependent response to oxidative stress mitochondrion organization signal transduction multicellular organismal development visual perception transcription factor binding hemopoiesis cell differentiation erythrocyte differentiation lung development histone acetyltransferase binding norepinephrine metabolic process surfactant homeostasis sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity cell maturation	Pathways in cancer Renal cell carcinoma
212502_at	-0.631	7.500	-3.742	1.921e-03	0.113	-1.173	ADO	2-aminoethanethiol (cysteamine) dioxygenase	10	64234521	AV713053	84890	10q21.3	Hs.99821	4	iron ion binding oxidoreductase activity metal ion binding cysteamine dioxygenase activity oxidation reduction	Taurine and hypotaurine metabolism Metabolic pathways
207660_at	0.626	4.226	3.740	1.928e-03	0.114	-1.177	DMD	dystrophin	X	-31106232, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265	NM_004019	1756	Xp21.2	Hs.495912	240	actin binding structural constituent of cytoskeleton calcium ion binding protein binding cytoplasm cytoskeleton muscle organ development zinc ion binding structural constituent of muscle structural constituent of muscle cell surface dystrophin-associated glycoprotein complex sarcolemma costamere peptide biosynthetic process nitric-oxide synthase binding	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
202263_at	-0.596	11.457	-3.738	1.938e-03	0.114	-1.181	CYB5R1	cytochrome b5 reductase 1	1	-201197624	NM_016243	51706	1p36.13-q41	Hs.334832	8	cytochrome-b5 reductase activity electron carrier activity membrane integral to membrane sterol biosynthetic process oxidoreductase activity oxidation reduction	Amino sugar and nucleotide sugar metabolism
225024_at	-0.497	6.693	-3.736	1.944e-03	0.114	-1.184	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B	20	36095361	AL117521	58490	20q11.21-q12	Hs.278839	7
226897_s_at	-0.762	5.631	-3.736	1.946e-03	0.114	-1.185	ZC3H7A	zinc finger CCCH-type containing 7A	16	-11751942	AW169959	29066	16p13-p12	Hs.371856	5	nucleic acid binding intracellular nucleus zinc ion binding metal ion binding
210024_s_at	-0.765	10.303	-3.735	1.949e-03	0.114	-1.186	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	2	181553356, 181553586	AB017644	10477	2q32.1	Hs.470804	20	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding nucleus cytoplasm ligase activity modification-dependent protein catabolic process regulation of growth post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
225339_at	-0.653	8.195	-3.735	1.949e-03	0.114	-1.187	SPAG9	sperm associated antigen 9	17	-46394534	BG290577	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
223168_at	-0.787	8.352	-3.735	1.949e-03	0.114	-1.187	RHOU	ras homolog gene family, member U	1	226937491	AL096776	58480	1q42.11-q42.3	Hs.647774	12	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding podosome GTPase activity protein binding GTP binding intracellular Golgi apparatus plasma membrane focal adhesion small GTPase mediated signal transduction regulation of cell shape Rac protein signal transduction actin cytoskeleton organization cell junction cell projection
213489_at	-0.865	7.624	-3.734	1.954e-03	0.114	-1.189	MAPRE2	microtubule-associated protein, RP/EB family, member 2	18	30810889, 30812205, 30875321	BE671156	10982	18q12.1-q12.2	Hs.532824	27	cytoplasm microtubule cell cycle mitosis signal transduction microtubule binding cell proliferation cell division
214733_s_at	-0.404	6.482	-3.733	1.956e-03	0.114	-1.190	YIPF1	Yip1 domain family, member 1	1	-54089993	AL031427	54432	1p33-p32.1	Hs.11923	9	membrane integral to membrane transport vesicle
212061_at	-0.661	7.260	-3.733	1.956e-03	0.114	-1.190	SR140	U2-associated SR140 protein	3	144203061	AB002330	23350	3q23	Hs.596572	4	nucleotide binding RNA binding RNA processing
226942_at	-0.645	5.788	-3.732	1.959e-03	0.114	-1.191	PHF20L1	PHD finger protein 20-like 1	8	133856785, 133856785, 133856785	AI742668	51105	8q24.22	Hs.304362	4	nucleic acid binding protein binding zinc ion binding metal ion binding
226178_at	-0.674	5.352	-3.731	1.963e-03	0.114	-1.193	SOCS4	suppressor of cytokine signaling 4	14	54563593	BF446961	122809	14q22.2-q22.3	Hs.708344	7	protein binding intracellular signaling cascade negative regulation of signal transduction modification-dependent protein catabolic process regulation of growth	Jak-STAT signaling pathway Insulin signaling pathway Type II diabetes mellitus
219232_s_at	-0.695	3.685	-3.730	1.968e-03	0.115	-1.196	EGLN3	egl nine homolog 3 (C. elegans)	14	-33463171	NM_022073	112399	14q13.1	Hs.135507	26	iron ion binding protein binding nucleus cytoplasm apoptosis oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
214552_s_at	-1.072	5.461	-3.730	1.970e-03	0.115	-1.196	RABEP1	rabaptin, RAB GTPase binding effector protein 1	17	5126281	AF098638	9135	17p13.2	Hs.584784 Hs.592121	19	GTPase activator activity protein binding cytoplasm early endosome endocytosis apoptosis membrane fusion growth factor activity protein transport recycling endosome	Endocytosis
227534_at	-0.767	6.441	-3.729	1.972e-03	0.115	-1.198	C9orf21	chromosome 9 open reading frame 21	9	-98443353	AI655189	195827	9q22.32	Hs.44640	4
206847_s_at	0.854	7.004	3.725	1.988e-03	0.115	-1.205	HOXA7	homeobox A7	7	-27159862	AF026397	3204	7p15-p14	Hs.660918	24	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding negative regulation of keratinocyte differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
224559_at	-0.861	7.327	-3.725	1.989e-03	0.115	-1.205	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AF001540	378938	11q13.1	Hs.642877 Hs.714394	8
212877_at	-0.639	7.090	-3.724	1.993e-03	0.115	-1.207	KLC1	kinesin light chain 1	14	103165277, 103165277	AA284075	3831	14q32.3	Hs.20107 Hs.657678	31	microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle
218829_s_at	-0.522	6.856	-3.724	1.993e-03	0.115	-1.207	CHD7	chromodomain helicase DNA binding protein 7	8	61753892	NM_017780	55636	8q12.1-q12.2	Hs.20395	36	nucleotide binding chromatin skeletal system development blood vessel development in utero embryonic development heart morphogenesis DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly central nervous system development adult heart development sensory perception of sound locomotory behavior adult walking behavior blood circulation chromatin modification hydrolase activity cranial nerve development T cell differentiation female genitalia development embryonic hindlimb morphogenesis positive regulation of multicellular organism growth inner ear morphogenesis nose development regulation of transcription cognition palate development retina development in camera-type eye regulation of growth hormone secretion limb development face development
224722_at	-0.534	5.014	-3.722	2.000e-03	0.115	-1.210	MIB1	mindbomb homolog 1 (Drosophila)	18	17575542	BE048628	57534	18q11.2	Hs.140903 Hs.658808	15	blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding
201686_x_at	-0.424	5.513	-3.722	2.001e-03	0.115	-1.211	API5	apoptosis inhibitor 5	11	43290080	AF229254	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
209106_at	-0.607	7.862	-3.720	2.011e-03	0.116	-1.215	NCOA1	nuclear receptor coactivator 1	2	24660849	BF576458	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
204198_s_at	0.443	3.687	3.716	2.026e-03	0.116	-1.222	RUNX3	runt-related transcription factor 3	1	-25098588, -25098588	AA541630	864	1p36	Hs.170019	95	transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter induction of apoptosis cell proliferation negative regulation of cell cycle negative regulation of epithelial cell proliferation
219269_at	1.718	6.784	3.716	2.026e-03	0.116	-1.222	HMBOX1	homeobox containing 1	8	28803829, 28804143	NM_024567	79618	8p21.1	Hs.591836	5	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
201635_s_at	-0.826	9.811	-3.716	2.026e-03	0.116	-1.222	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	AI990766	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
218546_at	0.729	6.346	3.713	2.040e-03	0.116	-1.228	C1orf115	chromosome 1 open reading frame 115	1	218930250	NM_024709	79762	1q41	Hs.519839	6	membrane integral to membrane
225477_s_at	-0.583	7.335	-3.713	2.040e-03	0.116	-1.228	NR2C2	nuclear receptor subfamily 2, group C, member 2	3	14964239	AL138444	7182	3p25	Hs.555973	22	transcription factor activity steroid hormone receptor activity transcription coactivator activity nucleus nucleolus regulation of transcription, DNA-dependent nervous system development zinc ion binding sequence-specific DNA binding metal ion binding spermatocyte division
211652_s_at	-1.973	4.811	-3.712	2.041e-03	0.116	-1.229	LBP	lipopolysaccharide binding protein	20	36408298	M35533	3929	20q11.23-q12	Hs.154078	58	lipopolysaccharide binding macrophage activation during immune response receptor binding extracellular region extracellular region extracellular space extracellular space nucleus lipid transport acute-phase response acute-phase response cellular defense response opsonization opsonization lipid binding lipopolysaccharide transport lipopolysaccharide-mediated signaling pathway detection of molecule of bacterial origin response to lipopolysaccharide negative regulation of tumor necrosis factor production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 4 signaling pathway positive regulation of macrophage activation cell surface binding innate immune response innate immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium Gram-negative bacterial cell surface binding Gram-negative bacterial cell surface binding Gram-positive bacterial cell surface binding positive regulation of respiratory burst during acute inflammatory response	Toll-like receptor signaling pathway
200992_at	-0.397	9.968	-3.712	2.042e-03	0.116	-1.230	IPO7	importin 7	11	9362744	AL137335	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
206567_s_at	-0.727	7.452	-3.709	2.054e-03	0.116	-1.235	PHF20	PHD finger protein 20	20	33823336	NM_016436	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
202578_s_at	-0.573	6.202	-3.707	2.065e-03	0.117	-1.239	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A	16	68938324	NM_018332	55308	16q22.1	Hs.656037	5	nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport
213885_at	0.349	5.643	3.706	2.067e-03	0.117	-1.240	TRIM3	tripartite motif-containing 3	11	-6426418	AA114843	10612	11p15.5	Hs.591992	11	intracellular cytoplasm early endosome nervous system development protein C-terminus binding zinc ion binding protein transport metal ion binding
218193_s_at	-0.751	5.717	-3.705	2.072e-03	0.117	-1.243	GOLT1B	golgi transport 1 homolog B (S. cerevisiae)	12	21545965	NM_016072	51026	12p12.1	Hs.62275	10	signal transducer activity endoplasmic reticulum Golgi apparatus protein transport membrane integral to membrane vesicle-mediated transport positive regulation of I-kappaB kinase/NF-kappaB cascade
243309_at	-0.833	5.284	-3.704	2.075e-03	0.117	-1.244	FLJ27352	hypothetical LOC145788	15		AA398658	145788	15q21.3	Hs.97300
226342_at	-0.761	6.899	-3.702	2.085e-03	0.117	-1.249	SPTBN1	spectrin, beta, non-erythrocytic 1	2	54536957, 54639034	AW593244	6711	2p21	Hs.503178 Hs.705692	46	actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping
221207_s_at	0.678	6.864	3.701	2.089e-03	0.117	-1.250	NBEA	neurobeachin	13	34414455	NM_015678	26960	13q13	Hs.491172	11	protein binding cytoplasm trans-Golgi network cytosol plasma membrane protein localization endomembrane system protein kinase binding
221823_at	-0.727	5.944	-3.699	2.097e-03	0.117	-1.254	C5orf30	chromosome 5 open reading frame 30	5	102622340	AL565741	90355	5q21.1	Hs.482976	4
225805_at	-0.763	5.331	-3.699	2.098e-03	0.117	-1.254	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	AW137669	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
205975_s_at	0.549	4.748	3.699	2.099e-03	0.117	-1.255	HOXD1	homeobox D1	2	176761552	NM_024501	3231	2q31.1	Hs.83465	14	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding
217599_s_at	-1.133	5.959	-3.699	2.100e-03	0.117	-1.255	MDFIC	MyoD family inhibitor domain containing	7	114349444	BE910600	29969	7q31.1-q31.2	Hs.427236	7	nucleus nucleolus cytoplasm activation of JUN kinase activity regulation of Wnt receptor signaling pathway cyclin binding Tat protein binding interspecies interaction between organisms regulation of transcription positive regulation of viral transcription
224413_s_at	-0.582	7.148	-3.698	2.102e-03	0.117	-1.256	TM2D2	TM2 domain containing 2	8	-38965483	AF353991	83877	8p11.22	Hs.7471	5	membrane integral to membrane
230284_at	-1.012	6.234	-3.698	2.104e-03	0.117	-1.257	MYOM3	myomesin family, member 3	1	-24255117	BF108688	127294	1p36.11	Hs.523413	4
232149_s_at	-0.663	5.613	-3.697	2.109e-03	0.118	-1.259	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	8	-59658619, -59658619	BF056507	8439	8q12-q13	Hs.372000	8	receptor signaling protein activity soluble fraction cytoplasm ceramide metabolic process signal transduction
200818_at	0.408	12.156	3.697	2.109e-03	0.118	-1.259	ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	21	-34197626	NM_001697	539	21q22.1-q22.2 21q22.11	Hs.409140	12	transporter activity mitochondrion mitochondrial proton-transporting ATP synthase complex mitochondrial proton-transporting ATP synthase complex plasma membrane ATP catabolic process ion transport drug binding proton transport ATPase activity mitochondrial ATP synthesis coupled proton transport proton-transporting ATP synthase complex, catalytic core F(1) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
231887_s_at	0.508	6.042	3.693	2.125e-03	0.118	-1.266	KIAA1274	KIAA1274	10	71908569	AB033100	27143	10q22.1	Hs.202351	5
206303_s_at	-0.614	6.900	-3.693	2.127e-03	0.118	-1.267	NUDT4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	12	92295831	AF191653	11163	12q21	Hs.506325	10	magnesium ion binding intracellular cytoplasm intracellular signaling cascade diphosphoinositol-polyphosphate diphosphatase activity cyclic nucleotide metabolic process hydrolase activity calcium-mediated signaling cyclic-nucleotide-mediated signaling manganese ion binding regulation of RNA export from nucleus intracellular transport
231845_at	0.345	5.932	3.692	2.130e-03	0.118	-1.268	AARS2	alanyl-tRNA synthetase 2, mitochondrial (putative)	6	-44374440	AI721172	57505	6p21.1	Hs.158381	7	nucleotide binding nucleic acid binding alanine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix translation alanyl-tRNA aminoacylation ligase activity tRNA aminoacylation	Aminoacyl-tRNA biosynthesis
218330_s_at	1.115	5.815	3.691	2.135e-03	0.118	-1.270	NAV2	neuron navigator 2	11	19328846, 19691456, 20001211	NM_018162	89797	11p15.1	Hs.502116 Hs.551898 Hs.639427 Hs.639428	18	nucleotide binding helicase activity ATP binding nucleus nucleolus cytoplasm hydrolase activity
1554863_s_at	-0.697	7.602	-3.691	2.136e-03	0.118	-1.271	DOK5	docking protein 5	20	52525672	BC008992	55816	20q13.2	Hs.656582	10	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
1568618_a_at	-0.870	7.864	-3.690	2.138e-03	0.118	-1.271	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	BC038440	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
221898_at	-0.708	6.126	-3.689	2.141e-03	0.118	-1.273	PDPN	podoplanin	1	13782838, 13784553	AU154455	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
201591_s_at	0.422	7.508	3.688	2.147e-03	0.118	-1.275	NISCH	nischarin	3	52464563	NM_007184	11188	3p21.1	Hs.435290	16	receptor activity integrin binding protein binding membrane fraction cytoplasm early endosome cytosol plasma membrane glucose metabolic process apoptosis cell communication regulation of blood pressure amine receptor activity Rac protein signal transduction actin cytoskeleton organization negative regulation of cell migration regulation of synaptic transmission, GABAergic phosphoinositide binding norepinephrine secretion recycling endosome
204225_at	-0.933	7.940	-3.688	2.149e-03	0.118	-1.276	HDAC4	histone deacetylase 4	2	-239634800	NM_006037	9759	2q37.3	Hs.20516 Hs.688314	83	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter skeletal system development DNA binding histone deacetylase activity nucleus cytoplasm inflammatory response cell cycle multicellular organismal development nervous system development transcription factor binding negative regulation of cell proliferation transcription repressor activity chromatin modification hydrolase activity B cell differentiation positive regulation of protein sumoylation negative regulation of striated muscle development
213787_s_at	0.574	6.315	3.686	2.154e-03	0.118	-1.278	EBP	emopamil binding protein (sterol isomerase)	X	48265107	AV702405	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
219297_at	-0.469	6.172	-3.684	2.165e-03	0.119	-1.283	WDR44	WD repeat domain 44	X	117364069	NM_019045	54521	Xq24	Hs.98510	16	cytoplasm endosome Golgi apparatus cytosol endosome membrane membrane perinuclear region of cytoplasm
218891_at	-0.427	7.142	-3.684	2.166e-03	0.119	-1.284	C10orf76	chromosome 10 open reading frame 76	10	-103595345	NM_024541	79591	10q24.32	Hs.16004	4	membrane integral to membrane
201955_at	-0.513	7.090	-3.681	2.177e-03	0.119	-1.288	CCNC	cyclin C	6	-100096983	AL137784	892	6q21	Hs.430646 Hs.633351	31	protein binding nucleus regulation of transcription
212995_x_at	0.618	8.794	3.681	2.177e-03	0.119	-1.288	FAM128B	family with sequence similarity 128, member B	2	130656172	BG255188	80097	2q21.1	Hs.469925 Hs.516450	2
201078_at	-0.737	7.859	-3.680	2.182e-03	0.119	-1.290	TM9SF2	transmembrane 9 superfamily member 2	13	98951728	NM_004800	9375	13q32.3	Hs.654824	9	endosome integral to plasma membrane transport membrane
212307_s_at	-0.496	7.187	-3.680	2.184e-03	0.119	-1.291	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	70669657	BF001665	8473	Xq13	Hs.405410	47	protein binding nucleus cytoplasm cytosol protein amino acid O-linked glycosylation signal transduction response to nutrient acetylglucosaminyltransferase activity transferase activity, transferring glycosyl groups MLL5-L complex	O-Glycan biosynthesis Metabolic pathways
201675_at	0.639	10.658	3.680	2.184e-03	0.119	-1.291	AKAP1	A kinase (PRKA) anchor protein 1	17	52517551	NM_003488	8165	17q21-q23	Hs.463506	27	RNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane membrane integral to membrane
200605_s_at	-0.931	9.785	-3.679	2.185e-03	0.119	-1.291	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	17	64019704, 64020137	NM_002734	5573	17q23-q24	Hs.280342	106	nucleotide binding mesoderm formation regulation of protein amino acid phosphorylation protein binding cAMP-dependent protein kinase complex regulation of transcription from RNA polymerase II promoter cAMP-dependent protein kinase regulator activity hormone-mediated signaling cAMP binding neuromuscular junction	Apoptosis Insulin signaling pathway
211559_s_at	-0.697	3.531	-3.679	2.185e-03	0.119	-1.292	CCNG2	cyclin G2	4	78297380	L49506	901	4q21.1	Hs.13291	12	cell cycle checkpoint cytoplasm cell cycle mitosis cell division	p53 signaling pathway
207196_s_at	-0.483	8.706	-3.678	2.191e-03	0.119	-1.294	TNIP1	TNFAIP3 interacting protein 1	5	-150389698	NM_006058	10318	5q32-q33.1	Hs.355141	31	protein binding intracellular nucleus cytoplasm translation defense response glycoprotein biosynthetic process pathogenesis negative regulation of viral genome replication
208598_s_at	-0.446	7.922	-3.678	2.192e-03	0.119	-1.295	HUWE1	HECT, UBA and WWE domain containing 1	X	-53575796	NM_005703	10075	Xp11.22	Hs.136905	28	protein polyubiquitination DNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm protein modification process histone ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation	Ubiquitin mediated proteolysis
207382_at	-0.839	8.137	-3.677	2.195e-03	0.119	-1.296	TP63	tumor protein p63	3	190831909, 190831909, 190990142, 190990142	NM_003722	8626	3q28	Hs.137569	238	response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization
201454_s_at	-0.714	9.084	-3.676	2.199e-03	0.119	-1.297	NPEPPS	aminopeptidase puromycin sensitive	17	42963442	AW055008	9520	17q21	Hs.443837	14	aminopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
226055_at	-1.057	7.210	-3.676	2.201e-03	0.119	-1.298	ARRDC2	arrestin domain containing 2	19	17972943, 17979976	AK000689	27106	19p13.11	Hs.515249	6
218966_at	0.689	6.083	3.674	2.211e-03	0.119	-1.302	MYO5C	myosin VC	15	-50271811	NM_018728	55930	15q21	Hs.487036	6	nucleotide binding motor activity calmodulin binding ATP binding myosin complex actin filament binding
205898_at	1.011	6.220	3.674	2.212e-03	0.119	-1.303	CX3CR1	chemokine (C-X3-C motif) receptor 1	3	-39279988	U20350	1524	3p21 3p21.3	Hs.78913	123	receptor activity G-protein coupled receptor activity chemokine receptor activity protein binding plasma membrane integral to plasma membrane chemotaxis cellular defense response cell adhesion signal transduction G-protein coupled receptor protein signaling pathway response to wounding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway
212428_at	-0.740	9.043	-3.672	2.218e-03	0.120	-1.305	KIAA0368	KIAA0368	9	-113162793	AW001101	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
204998_s_at	1.933	6.902	3.670	2.227e-03	0.120	-1.309	ATF5	activating transcription factor 5	19	55123785	NM_012068	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
242660_at	0.873	3.258	3.669	2.232e-03	0.120	-1.311	C10orf112	chromosome 10 open reading frame 112	10		AA846789	340895	10p12.31	Hs.662505	4	membrane integral to membrane
228186_s_at	-0.803	8.382	-3.668	2.237e-03	0.120	-1.313	RSPO3	R-spondin 3 homolog (Xenopus laevis)	6	127481740	BF589322	84870	6q22.33	Hs.135254	10	extracellular region heparin binding Wnt receptor signaling pathway response to stimulus
225886_at	-0.470	6.944	-3.666	2.246e-03	0.120	-1.317	DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	17	-59924835	AA156797	1655	17q21	Hs.279806	50	nucleotide binding RNA binding RNA helicase activity protein binding ATP binding nucleus spliceosomal complex nucleolus mRNA processing ATP-dependent helicase activity RNA splicing cell growth hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
217783_s_at	-0.440	8.135	-3.666	2.246e-03	0.120	-1.317	YPEL5	yippee-like 5 (Drosophila)	2	30223253	NM_016061	51646	2p23.1	Hs.515890	6
218115_at	0.454	5.553	3.665	2.253e-03	0.120	-1.320	ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	19	-14091320	NM_018154	55723	19p13.12	Hs.26516	15	chromatin nucleus chromatin assembly or disassembly nucleosome assembly multicellular organismal development spermatogenesis chromatin modification cell differentiation histone binding regulation of transcription
219929_s_at	0.544	6.247	3.663	2.258e-03	0.120	-1.322	ZFYVE21	zinc finger, FYVE domain containing 21	14	103251897	NM_024071	79038	14q32.33	Hs.592322	4	zinc ion binding metal ion binding
203846_at	-0.628	7.396	-3.663	2.259e-03	0.120	-1.322	TRIM32	tripartite motif-containing 32	9	118489401	BC003154	22954	9q33.1	Hs.591910	18	transcription coactivator activity intracellular nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process ubiquitin binding protein self-association fat cell differentiation metal ion binding	Ubiquitin mediated proteolysis
217996_at	-0.942	5.076	-3.663	2.260e-03	0.120	-1.323	PHLDA1	pleckstrin homology-like domain, family A, member 1	12	-74705493	AA576961	22822	12q15	Hs.602085	15	protein binding nucleus nucleolus cytoplasm apoptosis membrane cytoplasmic vesicle membrane cytoplasmic vesicle FasL biosynthetic process
217781_s_at	-0.710	11.287	-3.663	2.262e-03	0.120	-1.323	ZFP106	zinc finger protein 106 homolog (mouse)	15	-40492312	NM_022473	64397	15q15.1	Hs.511143	9	opioid peptide activity intracellular membrane fraction nucleus nucleolus cytosol zinc ion binding insulin receptor signaling pathway SH3 domain binding metal ion binding
1555950_a_at	-0.829	7.589	-3.659	2.280e-03	0.121	-1.330	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	1	205561439	CA448665	1604	1q32	Hs.126517	118	soluble fraction plasma membrane integral to plasma membrane complement activation, classical pathway elevation of cytosolic calcium ion concentration anchored to membrane innate immune response membrane raft respiratory burst	Complement and coagulation cascades Hematopoietic cell lineage
1552770_s_at	0.431	4.807	3.659	2.280e-03	0.121	-1.331	ZNF563	zinc finger protein 563	19	-12289305	NM_145276	147837	19p13.2	Hs.663510	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203957_at	-0.663	6.571	-3.659	2.280e-03	0.121	-1.331	E2F6	E2F transcription factor 6	2	-11501951	NM_001952	1876	2p25.1	Hs.603093	24	regulation of transcription of G1/S-phase of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription corepressor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle
1554452_a_at	0.540	5.420	3.659	2.281e-03	0.121	-1.331	C7orf68	chromosome 7 open reading frame 68	7	127883119	BC001863	29923	7q32.1	Hs.710088	9	molecular_function cellular_component response to stress membrane integral to membrane
209513_s_at	0.583	9.661	3.658	2.283e-03	0.121	-1.332	HSDL2	hydroxysteroid dehydrogenase like 2	9	114182171	BC004331	84263	9q32	Hs.59486	6	binding sterol carrier activity oxidoreductase activity oxidation reduction
224616_at	-0.403	9.374	-3.658	2.284e-03	0.121	-1.332	DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2	16	-65312299	BG110975	1783	16q22.1	Hs.369068	10	nucleotide binding motor activity ATP binding cytoplasmic dynein complex microtubule
223339_at	0.606	7.497	3.655	2.299e-03	0.122	-1.338	ATPIF1	ATPase inhibitory factor 1	1	28435197	BC001867	93974		Hs.590908	13	angiogenesis negative regulation of endothelial cell proliferation calmodulin binding mitochondrion mitochondrion mitochondrial proton-transporting ATP synthase complex generation of precursor metabolites and energy cell surface ATPase inhibitor activity ATPase inhibitor activity protein homodimerization activity angiostatin binding negative regulation of nucleotide metabolic process ATPase binding ATPase binding protein homotetramerization negative regulation of hydrolase activity negative regulation of hydrolase activity
225972_at	-1.036	6.355	-3.654	2.303e-03	0.122	-1.340	TMEM64	transmembrane protein 64	8	-91703398	AA524005	169200	8q21.3	Hs.567759	2	membrane integral to membrane
206891_at	-2.740	9.865	-3.654	2.303e-03	0.122	-1.340	ACTN3	actinin, alpha 3	11	66070966	NM_001104	89	11q13.1	Hs.654432	47	actin binding integrin binding calcium ion binding protein binding actin filament focal adhesion structural constituent of muscle pseudopodium protein homodimerization activity regulation of apoptosis focal adhesion formation	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
202842_s_at	-0.603	8.301	-3.653	2.305e-03	0.122	-1.341	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	AL080081	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
207550_at	0.490	3.170	3.652	2.314e-03	0.122	-1.344	MPL	myeloproliferative leukemia virus oncogene	1	43576061	NM_005373	4352	1p34	Hs.82906	85	cytokine receptor activity plasma membrane integral to plasma membrane cell surface receptor linked signal transduction cell proliferation	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
225814_at	-0.610	8.189	-3.651	2.315e-03	0.122	-1.344	XRN1	5'-3' exoribonuclease 1	3	-143508138	BG534738	54464	3q23	Hs.435103	12	DNA binding RNA binding protein binding intracellular cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5'-3' exonuclease activity hydrolase activity	RNA degradation
221483_s_at	-0.453	9.330	-3.651	2.315e-03	0.122	-1.345	ARPP19	cAMP-regulated phosphoprotein, 19kDa	15	-50626723	AF084555	10776	15q21.2	Hs.512908	10	receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import
230405_at	0.410	7.327	3.651	2.316e-03	0.122	-1.345	C5orf56	chromosome 5 open reading frame 56	5	131774571	AI143416	441108	5q31.1	Hs.658288	1
239213_at	0.448	4.754	3.649	2.329e-03	0.122	-1.350	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	6	-2778732	W52010	1992	6p25	Hs.381167	18	serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity
224437_s_at	-0.594	8.207	-3.648	2.329e-03	0.122	-1.350	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	BC005937	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
209895_at	-1.430	5.951	-3.648	2.330e-03	0.122	-1.351	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	AF119855	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
224376_s_at	-0.782	10.037	-3.646	2.340e-03	0.122	-1.354	C20orf24	chromosome 20 open reading frame 24	20	34667580, 34667605	AF274948	55969	20q11.23	Hs.584985	7	molecular_function protein binding cellular_component biological_process
208884_s_at	-0.661	7.241	-3.645	2.345e-03	0.122	-1.357	UBR5	ubiquitin protein ligase E3 component n-recognin 5	8	-103334744	AF006010	51366	8q22	Hs.591856	21	RNA binding ubiquitin-protein ligase activity protein binding intracellular soluble fraction nucleus protein modification process ubiquitin-dependent protein catabolic process response to DNA damage stimulus zinc ion binding cell proliferation ligase activity acid-amino acid ligase activity metal ion binding progesterone receptor signaling pathway	Ubiquitin mediated proteolysis
201946_s_at	-0.859	8.231	-3.644	2.350e-03	0.122	-1.358	CCT2	chaperonin containing TCP1, subunit 2 (beta)	12	68265474	AL545982	10576	12q15	Hs.189772	19	nucleotide binding ATP binding nucleus nucleolus cytoplasm cytosol chaperonin-containing T-complex protein folding unfolded protein binding
203785_s_at	-0.605	6.058	-3.642	2.362e-03	0.123	-1.363	DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	16	-66612674	NM_018380	55794	16q22.1	Hs.458313	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mitochondrion ATP-dependent helicase activity hydrolase activity mitochondrial nucleoid
208322_s_at	-0.585	7.144	-3.638	2.380e-03	0.124	-1.370	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	8	-134536272	NM_003033	6482	8q24.22	Hs.374257	20	beta-galactoside alpha-2,3-sialyltransferase activity extracellular region Golgi apparatus protein amino acid glycosylation membrane integral to membrane integral to Golgi membrane	O-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
217115_at	0.378	5.152	3.637	2.386e-03	0.124	-1.372	LOC100240726	makorin ring finger protein 1 pseudogene	20	-44525707	AL031686	100240726	20q13.12		1
225323_at	-0.352	5.917	-3.634	2.399e-03	0.124	-1.377	CC2D1B	coiled-coil and C2 domain containing 1B	1	-52588854	AW514783	200014	1p32.3	Hs.591451	6
212250_at	-0.744	7.994	-3.634	2.399e-03	0.124	-1.377	MTDH	metadherin	8	98725582	AV700332	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
203327_at	-0.596	8.398	-3.633	2.405e-03	0.124	-1.379	IDE	insulin-degrading enzyme	10	-94203579	N22903	3416	10q23-q25	Hs.500546	94	metalloendopeptidase activity signal transducer activity ATP binding extracellular space soluble fraction cytoplasm peroxisome proteolysis signal transduction sex differentiation peptidase activity zinc ion binding bradykinin catabolic process protein homodimerization activity metal ion binding beta-amyloid metabolic process	Alzheimer's disease
1552610_a_at	-0.868	6.479	-3.631	2.417e-03	0.125	-1.384	JAK1	Janus kinase 1	1	-65071493	NM_002227	3716	1p32.3-p31.3	Hs.207538	118	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity growth hormone receptor binding protein binding ATP binding nucleus cytoplasm cytoskeleton enzyme linked receptor protein signaling pathway protein kinase cascade membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway response to antibiotic	Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer
229840_at	0.372	5.819	3.629	2.425e-03	0.125	-1.387	IQSEC2	IQ motif and Sec7 domain 2	X	-53312230, -53278789, -53278782	AW026036	23096	Xp11.22	Hs.496138	10	ARF guanyl-nucleotide exchange factor activity intracellular cytoplasm regulation of ARF protein signal transduction	Endocytosis
238228_at	-0.816	4.849	-3.629	2.425e-03	0.125	-1.387	COG3	component of oligomeric golgi complex 3	13	44937071	AI732206	83548	13q14.13	Hs.507948	15	Golgi apparatus cis-Golgi network protein amino acid glycosylation intracellular protein transport ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport protein transporter activity membrane Golgi transport complex protein localization in organelle protein stabilization
212427_at	-0.961	7.057	-3.629	2.426e-03	0.125	-1.388	KIAA0368	KIAA0368	9	-113162793	AB002366	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
232306_at	0.338	3.172	3.629	2.426e-03	0.125	-1.388	CDH26	cadherin-like 26	20	57966876, 58004823	BG289314	60437	20q13.2-q13.33	Hs.54973	4	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
222735_at	-0.833	9.485	-3.628	2.427e-03	0.125	-1.388	TMEM38B	transmembrane protein 38B	9	107496645	AW452608	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
1558668_s_at	0.647	2.445	3.628	2.431e-03	0.125	-1.389	SPATA22	spermatogenesis associated 22	17	-3290063	AW072392	84690	17p13.3	Hs.351068	3
230090_at	-1.999	5.755	-3.628	2.431e-03	0.125	-1.389	GDNF	glial cell derived neurotrophic factor	5	-37851509, -37851509, -37851509	AW296078	2668	5p13.1-p12	Hs.248114	86	neural crest cell migration extracellular region anti-apoptosis signal transduction nervous system development growth factor activity adult locomotory behavior positive regulation of specific transcription from RNA polymerase II promoter neuron projection development positive regulation of monooxygenase activity positive regulation of dopamine secretion protein homodimerization activity negative regulation of neuron apoptosis mRNA stabilization regulation of dopamine uptake
238864_at	0.427	5.488	3.627	2.436e-03	0.125	-1.391	VWA3A	von Willebrand factor A domain containing 3A	16	22011363	AI559649	146177	16p12.2	Hs.10697	4	extracellular region
1559705_s_at	0.325	5.647	3.627	2.436e-03	0.125	-1.391	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	X73875	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
228930_at	-0.721	6.512	-3.627	2.437e-03	0.125	-1.392	SCARNA15	small Cajal body-specific RNA 15	15	81221750	AI679611	677778	15q25.2	Hs.513091	1
220512_at	0.366	4.901	3.624	2.449e-03	0.125	-1.396	DLC1	deleted in liver cancer 1	8	-13116452, -12985242, -12985242	NM_024767	10395	8p22	Hs.134296	48	neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation
212758_s_at	-0.828	8.044	-3.624	2.450e-03	0.125	-1.397	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	AI373166	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
234854_at	0.417	3.278	3.622	2.462e-03	0.125	-1.401	MDN1	MDN1, midasin homolog (yeast)	6	-90409951	AL096678	23195	6q15	Hs.529948	7	nucleotide binding ATP binding nucleus ATPase activity regulation of protein complex assembly unfolded protein binding
204773_at	0.340	7.128	3.622	2.462e-03	0.125	-1.401	IL11RA	interleukin 11 receptor, alpha	9	34642181, 34643931, 34643931	NM_004512	3590	9p13	Hs.591088	26	cytokine receptor activity integral to plasma membrane membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
213929_at	0.604	2.932	3.619	2.476e-03	0.126	-1.406	EXPH5	exophilin 5	11	-107881367, -107881367, -107881367	AL050204	23086	11q22.3	Hs.28540	8	protein binding intracellular protein transport Rab GTPase binding
226735_at	-0.694	7.036	-3.617	2.483e-03	0.126	-1.409	TAPT1	transmembrane anterior posterior transformation 1	4	-15771225	AI239899	202018	4p15.32	Hs.479223	5	receptor activity multicellular organismal development membrane integral to membrane
205206_at	-1.280	7.950	-3.617	2.484e-03	0.126	-1.409	KAL1	Kallmann syndrome 1 sequence	X	-8456914	NM_000216	3730	Xp22.32	Hs.521869	35	serine-type endopeptidase inhibitor activity extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix extracellular space chemotaxis cell adhesion axon guidance cell surface peptidase inhibitor activity
206156_at	0.379	3.596	3.617	2.485e-03	0.126	-1.410	GJB5	gap junction protein, beta 5, 31.1kDa	1	34993307	NM_005268	2709	1p35.1	Hs.198249	5	plasma membrane connexon complex cell communication epidermis development integral to membrane cell junction
206647_at	0.383	4.149	3.616	2.492e-03	0.126	-1.412	HBZ	hemoglobin, zeta	16	142853	NM_005332	3050	16p13.3	Hs.585357	24	oxygen transporter activity hemoglobin complex transport oxygen transport oxygen binding heme binding metal ion binding
225324_at	-0.835	7.581	-3.615	2.493e-03	0.126	-1.413	CRLS1	cardiolipin synthase 1	20	5934738, 5935897	AL035461	54675	20p13-p12.3	Hs.224764	14	mitochondrion mitochondrial inner membrane phospholipid biosynthetic process membrane integral to membrane transferase activity phosphotransferase activity, for other substituted phosphate groups	Glycerophospholipid metabolism Metabolic pathways
1556325_at	-0.841	8.240	-3.615	2.494e-03	0.126	-1.413	FILIP1	filamin A interacting protein 1	6	-76074519	AL832009	27145	6q14.1	Hs.696158	9
210426_x_at	-0.936	5.791	-3.609	2.526e-03	0.128	-1.424	RORA	RAR-related orphan receptor A	15	-58567776, -58567776, -58567776	U04897	6095	15q22.2	Hs.560343 Hs.655155	33	transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding
226267_at	-0.683	6.423	-3.606	2.541e-03	0.128	-1.430	JDP2	Jun dimerization protein 2	14	74964261, 74964672, 74964812, 74968589	AA716425	122953	14q24.3	Hs.196482	15	negative regulation of transcription from RNA polymerase II promoter transcription factor activity nucleus regulation of transcription, DNA-dependent transcription repressor activity sequence-specific DNA binding protein dimerization activity
242338_at	-0.498	4.707	-3.605	2.549e-03	0.128	-1.433	TMEM64	transmembrane protein 64	8	-91703398	BG535396	169200	8q21.3	Hs.567759	2	membrane integral to membrane
230285_at	-0.625	5.014	-3.604	2.553e-03	0.128	-1.434	SVIP	small VCP/p97-interacting protein	11	-22800173	BF447829	258010	11p14.2	Hs.349096	4	endoplasmic reticulum Golgi apparatus plasma membrane
1563290_at	0.386	5.303	3.603	2.556e-03	0.128	-1.435	DNAH3	dynein, axonemal, heavy chain 3	16	-20851976	Z83805	55567	16p12.3	Hs.526500	7	nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme	Huntington's disease
1554549_a_at	-0.793	3.234	-3.603	2.559e-03	0.128	-1.437	WDR20	WD repeat domain 20	14	101675964, 101675964, 101675964	BC030654	91833	14q32.31	Hs.36859	7
202978_s_at	-0.620	5.295	-3.601	2.570e-03	0.129	-1.440	CREBZF	CREB/ATF bZIP transcription factor	11	-85046257	AW204564	58487	11q14	Hs.535319 Hs.595940 Hs.714910	12	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent response to virus negative regulation of transcription specific transcriptional repressor activity sequence-specific DNA binding negative regulation of gene expression, epigenetic regulation of transcription factor activity
208680_at	-0.596	10.706	-3.600	2.572e-03	0.129	-1.441	PRDX1	peroxiredoxin 1	1	-45749293	L19184	5052	1p34.1	Hs.180909	62	skeletal system development protein binding nucleus cytoplasm mitochondrion cell proliferation oxidoreductase activity melanosome hydrogen peroxide catabolic process cell redox homeostasis peroxiredoxin activity oxidation reduction
209004_s_at	0.504	10.040	3.599	2.579e-03	0.129	-1.444	FBXL5	F-box and leucine-rich repeat protein 5	4	-15215251	AF142481	26234	4p15.32	Hs.643433	13	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process
217725_x_at	-0.834	8.721	-3.598	2.584e-03	0.129	-1.445	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	NM_015640	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
209657_s_at	-0.942	8.384	-3.597	2.590e-03	0.129	-1.448	HSF2	heat shock transcription factor 2	6	122762394	M65217	3298	6q22.31	Hs.158195	28	transcription factor activity transcription coactivator activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress spermatogenesis protein homodimerization activity sequence-specific DNA binding
211994_at	-0.541	9.340	-3.596	2.595e-03	0.129	-1.449	WNK1	WNK lysine deficient protein kinase 1	12	732485	AI742553	65125	12p13.3	Hs.709894	51	nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process
229178_at	0.483	4.428	3.594	2.606e-03	0.129	-1.453	PRTG	protogenin homolog (Gallus gallus)	15	-53691041	AV699825	283659	15q21.3	Hs.130957	4	multicellular organismal development membrane integral to membrane
211744_s_at	-0.680	5.471	-3.594	2.609e-03	0.129	-1.454	CD58	CD58 molecule	1	-116862845, -116858679	BC005930	965	1p13	Hs.34341	38	protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane	Cell adhesion molecules (CAMs)
201764_at	0.553	7.300	3.593	2.612e-03	0.129	-1.455	TMEM106C	transmembrane protein 106C	12	46643596	NM_024056	79022	12q13.1	Hs.596726	5	molecular_function cellular_component endoplasmic reticulum biological_process membrane integral to membrane
203732_at	-0.529	5.886	-3.593	2.614e-03	0.129	-1.456	TRIP4	thyroid hormone receptor interactor 4	15	62467072	NM_016213	9325	15q22.31	Hs.500340	9	transcription coactivator activity nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter zinc ion binding ligand-dependent nuclear receptor binding regulation of transcription metal ion binding
224445_s_at	0.425	7.772	3.593	2.614e-03	0.129	-1.456	ZFYVE21	zinc finger, FYVE domain containing 21	14	103251897	BC005999	79038	14q32.33	Hs.592322	4	zinc ion binding metal ion binding
219751_at	-0.634	5.538	-3.591	2.621e-03	0.129	-1.458	SETD6	SET domain containing 6	16	57106883	NM_024860	79918	16q21	Hs.592060	5
201699_at	-0.545	9.470	-3.588	2.636e-03	0.130	-1.464	PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	14	52243645	NM_002806	5706	14q22.1	Hs.156171 Hs.718586	45	nucleotide binding proteasome complex ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process protein binding, bridging anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
206392_s_at	0.718	3.499	3.588	2.640e-03	0.130	-1.465	RARRES1	retinoic acid receptor responder (tazarotene induced) 1	3	-159905133, -159897590	NM_002888	5918	3q25.32	Hs.131269	11	negative regulation of cell proliferation membrane integral to membrane
203525_s_at	-0.839	7.366	-3.587	2.642e-03	0.130	-1.466	APC	adenomatous polyposis coli	5	112071116, 112101454	AI375486	324	5q21-q22	Hs.158932	386	cytokinesis after mitosis kinetochore kidney development hair follicle development nucleus cytoplasm centrosome cytosol cytoplasmic microtubule protein complex assembly response to DNA damage stimulus negative regulation of microtubule depolymerization cell cycle arrest mitotic metaphase/anaphase transition mitotic cell cycle spindle assembly checkpoint axonogenesis beta-catenin binding microtubule binding axis specification anterior/posterior pattern formation dorsal/ventral pattern formation proximal/distal pattern formation lateral plasma membrane protein kinase regulator activity protein kinase binding negative regulation of Wnt receptor signaling pathway positive regulation of cell migration growth cone positive regulation of epithelial cell differentiation beta-catenin destruction complex positive regulation of microtubule polymerization cell projection membrane positive regulation of pseudopodium assembly T cell differentiation in the thymus axon part Axin-APC-beta-catenin-GSK3B complex somatic stem cell maintenance negative regulation of odontogenesis cell projection positive regulation of apoptosis negative regulation of apoptosis negative regulation of MAPKKK cascade skin development regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process negative regulation of cyclin-dependent protein kinase activity positive regulation of cell adhesion muscle maintenance thymus development negative regulation of epithelial cell proliferation regulation of nitrogen compound metabolic process chromosome organization regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye Wnt receptor signaling pathway through beta-catenin Wnt receptor signaling pathway through beta-catenin	Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma
202057_at	-0.694	7.254	-3.587	2.644e-03	0.130	-1.467	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	BC002374	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
31846_at	0.412	8.470	3.586	2.649e-03	0.130	-1.468	RHOD	ras homolog gene family, member D	11	66580864	AW003733	29984	11q14.3	Hs.15114	22	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction	Axon guidance
217957_at	0.606	8.066	3.585	2.657e-03	0.130	-1.471	C16orf80	chromosome 16 open reading frame 80	16	-56704997	NM_013242	29105	16q21	Hs.532755	3	multicellular organismal development
223126_s_at	-0.656	7.260	-3.584	2.659e-03	0.130	-1.472	C1orf21	chromosome 1 open reading frame 21	1	182622772	AI159874	81563	1q25	Hs.497159 Hs.719188	8
226127_at	-0.557	7.177	-3.584	2.660e-03	0.130	-1.472	ALKBH3	alkB, alkylation repair homolog 3 (E. coli)	11	43858932	BF062547	221120	11p11.2	Hs.368920	11	damaged DNA binding iron ion binding nucleus nucleoplasm cytoplasm mitochondrion DNA repair response to DNA damage stimulus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding metal ion binding oxidation reduction
222730_s_at	-0.667	6.219	-3.584	2.663e-03	0.130	-1.473	ZDHHC2	zinc finger, DHHC-type containing 2	8	17058206	AI814257	51201	8p21.3-p22	Hs.443852	8	zinc ion binding membrane integral to membrane palmitoyltransferase activity transferase activity protein palmitoylation metal ion binding
203156_at	-0.595	7.454	-3.583	2.664e-03	0.130	-1.473	AKAP11	A kinase (PRKA) anchor protein 11	13	41744288	NM_016248	11215	13q14.11	Hs.105105	14	cytoplasm centrosome protein kinase cascade protein phosphatase 1 binding protein kinase A binding
222657_s_at	-0.747	6.919	-3.583	2.667e-03	0.130	-1.474	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	8	-74865393	AK024050	55284	8q21.11	Hs.597486	7	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
203693_s_at	-0.540	6.387	-3.582	2.673e-03	0.130	-1.476	E2F3	E2F transcription factor 3	6	20510115	NM_001949	1871	6p22	Hs.269408 Hs.703174	48	transcription factor activity protein binding nucleus nucleoplasm transcription factor complex regulation of transcription, DNA-dependent transcription initiation from RNA polymerase II promoter cell cycle	Cell cycle Pathways in cancer Pancreatic cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer
225061_at	-0.945	9.832	-3.582	2.673e-03	0.130	-1.476	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	15	76343541, 76344043, 76345614	N45231	55466	15q25.1	Hs.513053	5	protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding
226682_at	-0.879	8.536	-3.581	2.679e-03	0.130	-1.479	RORA	RAR-related orphan receptor A	15	-58567776, -58567776, -58567776	AW006185	6095	15q22.2	Hs.560343 Hs.655155	33	transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding
225029_at	-0.759	6.807	-3.581	2.680e-03	0.130	-1.479	LOC550643	hypothetical LOC550643	X	56772442	BE621082	550643	Xp11.1	Hs.355559	1
225071_at	-0.560	6.013	-3.580	2.684e-03	0.130	-1.480	NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	6	118103309	BG168247	116150	6q22.1	Hs.289008	6	angiogenesis molecular_function receptor activity cellular_component multicellular organismal development biological_process membrane integral to membrane transferase activity, transferring alkyl or aryl (other than methyl) groups cell differentiation
218111_s_at	-0.638	6.252	-3.580	2.685e-03	0.130	-1.481	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase	12	22090425	NM_018686	55907	12p12.1	Hs.311346	13	nucleus N-acylneuraminate cytidylyltransferase activity lipopolysaccharide biosynthetic process transferase activity nucleotidyltransferase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
217883_at	-0.412	11.057	-3.579	2.688e-03	0.130	-1.482	MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	2	-150134395	NM_015702	27249	2q23.2	Hs.5324	7	mitochondrion
219253_at	-0.728	5.031	-3.578	2.694e-03	0.130	-1.484	TMEM185B	transmembrane protein 185B (pseudogene)	2	-120695323	NM_024121	79134	2q14.2	Hs.376722	5	membrane integral to membrane
218919_at	-0.482	7.043	-3.578	2.695e-03	0.130	-1.484	ZFAND1	zinc finger, AN1-type domain 1	8	-82776512	NM_024699	79752	8q21.13	Hs.655453	4	zinc ion binding metal ion binding
212327_at	-0.515	9.537	-3.578	2.696e-03	0.130	-1.484	LIMCH1	LIM and calponin homology domains 1	4	41057560, 41309675	AK026815	22998	4p13	Hs.335163	10	actin binding zinc ion binding actomyosin structure organization metal ion binding
41577_at	0.595	5.424	3.575	2.711e-03	0.131	-1.490	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AB020630	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
36553_at	-0.837	6.751	-3.575	2.713e-03	0.131	-1.490	ASMTL	acetylserotonin O-methyltransferase-like	X, Y	-1482031, -1482031	AA669799	8623	Xp22.3 Yp11.3	Hs.533514	10	cellular_component cytoplasm acetylserotonin O-methyltransferase activity melatonin biosynthetic process
230025_at	0.491	5.927	3.573	2.719e-03	0.131	-1.492	GJD3	gap junction protein, delta 3, 31.9kDa	17	-35770430	BF508941	125111	17q21.2	Hs.444663	8	protein binding plasma membrane integral to plasma membrane connexon complex cell communication cell surface gap junction assembly cell junction
217726_at	-0.498	7.621	-3.573	2.720e-03	0.131	-1.492	COPZ1	coatomer protein complex, subunit zeta 1	12	53005177	NM_016057	22818	12q13.2-q13.3	Hs.505652	14	protein binding cytoplasm Golgi apparatus cytosol intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat COPI vesicle coat cytoplasmic vesicle COPI coating of Golgi vesicle
203076_s_at	-0.561	7.236	-3.573	2.721e-03	0.131	-1.493	SMAD2	SMAD family member 2	18	-43613464, -43613463, -43613463	U65019	4087	18q21.1	Hs.12253 Hs.705764	206	mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol	Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer
223002_s_at	-0.379	6.117	-3.567	2.758e-03	0.132	-1.505	XRN2	5'-3' exoribonuclease 2	20	21231941	AL136841	22803	20p11.2-p11.1	Hs.255932	18	DNA catabolic process, exonucleolytic nucleic acid binding 5'-3' exoribonuclease activity protein binding intracellular nucleus nucleolus transcription termination mRNA processing RNA catabolic process spermatogenesis zinc ion binding cell growth hydrolase activity regulation of transcription metal ion binding	RNA degradation
221815_at	-0.990	5.603	-3.566	2.760e-03	0.132	-1.506	ABHD2	abhydrolase domain containing 2	15	87432384	BE671816	11057	15q26.1	Hs.122337 Hs.705984	10	molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration
225643_at	-0.565	7.374	-3.566	2.764e-03	0.133	-1.507	MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	14	54588114	AI261542	93487	14q22.3	Hs.594338 Hs.619374	8
224477_s_at	0.447	6.507	3.565	2.767e-03	0.133	-1.508	NUDT16L1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1	16	4683716	BC006223	84309	16p13.3	Hs.592084	5	cytoplasm
203137_at	-0.603	8.932	-3.564	2.772e-03	0.133	-1.510	WTAP	Wilms tumor 1 associated protein	6	160068141, 160068141, 160068609	NM_004906	9589	6q25-q27	Hs.446091 Hs.710715	16	nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane
219600_s_at	-1.121	6.912	-3.562	2.783e-03	0.133	-1.513	TMEM50B	transmembrane protein 50B	21	-33743317	NM_006134	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
222471_s_at	-0.672	9.130	-3.562	2.787e-03	0.133	-1.515	KCMF1	potassium channel modulatory factor 1	2	85051741	AI743396	56888	2p11.2	Hs.654968	7	intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
202058_s_at	-1.098	5.315	-3.561	2.789e-03	0.133	-1.516	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	BC002374	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
224250_s_at	-0.661	7.930	-3.560	2.794e-03	0.133	-1.517	SECISBP2	SECIS binding protein 2	9	91123231	BC001189	79048	9q22.2	Hs.59804	20	RNA binding mRNA 3'-UTR binding nucleus translation
217955_at	-0.514	7.972	-3.560	2.794e-03	0.133	-1.517	BCL2L13	BCL2-like 13 (apoptosis facilitator)	22	16501484	NM_015367	23786	22q11.1	Hs.631672	12	nucleus mitochondrion induction of apoptosis activation of caspase activity caspase activator activity membrane integral to membrane regulation of apoptosis
235030_at	-0.650	6.982	-3.560	2.795e-03	0.133	-1.518	FAM55C	family with sequence similarity 55, member C	3	102980718, 102980975	BF969254	91775	3q12.3	Hs.595933	4	extracellular region
220495_s_at	-0.477	7.451	-3.557	2.812e-03	0.133	-1.523	TXNDC15	thioredoxin domain containing 15	5	134237358	NM_024715	79770	5q31.1	Hs.696335	7	membrane integral to membrane cell redox homeostasis
208998_at	1.140	9.646	3.557	2.814e-03	0.133	-1.524	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	11	-73363363	U94592	7351	11q13	Hs.80658	153	response to superoxide binding mitochondrion mitochondrial inner membrane transport mitochondrial transport proton transport membrane integral to membrane
201765_s_at	-0.351	7.537	-3.557	2.815e-03	0.133	-1.524	HEXA	hexosaminidase A (alpha polypeptide)	15	-70422831	AL523158	3073	15q23-q24	Hs.604479 Hs.709495	93	skeletal system development hydrolase activity, hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity protein binding lysosome carbohydrate metabolic process ganglioside catabolic process lysosome organization sensory perception of sound locomotory behavior adult walking behavior metabolic process membrane lipid storage sexual reproduction glycosaminoglycan metabolic process myelination cation binding protein heterodimerization activity neuromuscular process controlling posture neuromuscular process controlling balance	Other glycan degradation Amino sugar and nucleotide sugar metabolism Glycosaminoglycan degradation Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways Lysosome
218150_at	-0.517	9.360	-3.557	2.815e-03	0.133	-1.524	ARL5A	ADP-ribosylation factor-like 5A	2	-152365725	NM_012097	26225	2q23.3	Hs.470233	6	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
1554679_a_at	-1.974	8.658	-3.556	2.817e-03	0.133	-1.525	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	AF317417	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
210764_s_at	-2.045	5.000	-3.556	2.818e-03	0.133	-1.525	CYR61	cysteine-rich, angiogenic inducer, 61	1	85819031	AF003114	3491	1p31-p22	Hs.8867	82	regulation of cell growth patterning of blood vessels insulin-like growth factor binding extracellular region chemotaxis cell adhesion heparin binding cell proliferation anatomical structure morphogenesis positive regulation of cell-substrate adhesion extracellular matrix organization extracellular matrix binding
1564112_at	0.353	6.060	3.555	2.823e-03	0.133	-1.527	FAM71A	family with sequence similarity 71, member A	1	210864438	AK097437	149647	1q32.3	Hs.129293	4
201987_at	-0.451	9.704	-3.555	2.824e-03	0.133	-1.527	MED13	mediator complex subunit 13	17	-57374747	AI984051	9969	17q22-q23	Hs.282678	26	receptor activity nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
1552506_at	0.307	3.694	3.555	2.824e-03	0.133	-1.527	CRB2	crumbs homolog 2 (Drosophila)	9	125158268	NM_173689	286204	9q33.3	Hs.710092	7	calcium ion binding extracellular region plasma membrane visual perception integral to membrane response to stimulus
212128_s_at	-0.520	6.317	-3.554	2.831e-03	0.134	-1.529	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	3	49482568	AW411370	1605	3p21	Hs.707131 Hs.76111	56	morphogenesis of an epithelial sheet calcium ion binding protein binding extracellular region basement membrane extracellular space membrane fraction cytoplasm integral to plasma membrane protein complex assembly muscle contraction actin cytoskeleton dystroglycan complex sarcolemma membrane raft	ECM-receptor interaction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
232910_at	0.415	4.339	3.553	2.836e-03	0.134	-1.531	NCRNA00081	non-protein coding RNA 81	10	-112648478, -112648478	AK021501	92482	10q25.2	Hs.232543 Hs.651480	4	cytoplasm cilium
225320_at	-0.769	7.973	-3.552	2.844e-03	0.134	-1.533	CCDC109A	coiled-coil domain containing 109A	10	74121894	AA579630	90550	10q22.1	Hs.591366	2	membrane integral to membrane
1553634_a_at	0.436	4.011	3.551	2.851e-03	0.134	-1.536	FLJ40852	hypothetical LOC285962	7	-141050606	NM_173677	285962	7q34	Hs.17589	2
226043_at	0.367	6.571	3.550	2.857e-03	0.134	-1.538	GPSM1	G-protein signaling modulator 1 (AGS3-like, C. elegans)	9	138341752, 138341752, 138367329	AI242661	26086	9q34.3	Hs.239370	14	GTPase activator activity binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane signal transduction multicellular organismal development nervous system development cell differentiation
222222_s_at	-0.818	6.876	-3.549	2.858e-03	0.134	-1.538	HOMER3	homer homolog 3 (Drosophila)	19	-18901009, -18901009, -18901009, -18901009, -18901009	AC002985	9454	19p13.11	Hs.10326	16	protein binding cytoplasm plasma membrane protein targeting metabotropic glutamate receptor signaling pathway postsynaptic density cell junction synapse postsynaptic membrane
224654_at	-0.442	8.166	-3.549	2.861e-03	0.134	-1.539	DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	10	70385897	BG164358	9188	10q21	Hs.223141 Hs.576875	18	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus nucleolus hydrolase activity
213581_at	-0.819	5.606	-3.548	2.864e-03	0.134	-1.540	PDCD2	programmed cell death 2	6	-170732759, -170728374	BF446180	5134	6q27	Hs.367900	14	DNA binding protein binding nucleus cytoplasm apoptosis zinc ion binding metal ion binding
211862_x_at	-0.644	7.214	-3.548	2.865e-03	0.134	-1.540	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	AF015451	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
200804_at	-0.554	9.253	-3.548	2.867e-03	0.134	-1.541	TMBIM6	transmembrane BAX inhibitor motif containing 6	12	48421559, 48421858	NM_003217	7009	12q12-q13	Hs.35052 Hs.708025	20	insoluble fraction nucleus endoplasmic reticulum integral to plasma membrane spermatogenesis membrane negative regulation of apoptosis
234071_at	-0.512	3.755	-3.546	2.879e-03	0.134	-1.545	DEPDC6	DEP domain containing 6	8	120955080	AU147969	64798	8q24.12	Hs.112981	11	protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size
226161_at	-0.518	6.323	-3.546	2.880e-03	0.134	-1.545	SLC30A6	solute carrier family 30 (zinc transporter), member 6	2	32244436	BF793552	55676	2p22.3	Hs.23248	7	Golgi apparatus cation transport zinc ion transport zinc ion binding cation transmembrane transporter activity membrane integral to membrane
210246_s_at	0.614	5.357	3.545	2.883e-03	0.134	-1.546	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	11	-17371007	AF087138	6833	11p15.1	Hs.54470	111	nucleotide binding receptor activity ATP binding plasma membrane carbohydrate metabolic process transport potassium ion transport sulfonylurea receptor activity potassium ion transmembrane transporter activity integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters Type II diabetes mellitus
226008_at	-0.482	7.262	-3.545	2.883e-03	0.134	-1.546	NDNL2	necdin-like 2	15	-27347649	AA627644	56160	15q13.1	Hs.719283	8	protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of growth
202288_at	-0.371	5.971	-3.543	2.897e-03	0.135	-1.550	MTOR	mechanistic target of rapamycin (serine/threonine kinase)	1	-11089175	U88966	2475	1p36.2	Hs.338207	317	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum Golgi apparatus cytosol phosphoinositide 3-kinase complex signal transduction response to nutrient endomembrane system membrane cell growth kinase activity phosphotransferase activity, alcohol group as acceptor protein catabolic process TOR signaling pathway TORC1 complex TORC2 complex regulation of actin cytoskeleton organization response to amino acid stimulus protein amino acid autophosphorylation phosphoprotein binding	ErbB signaling pathway mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Pathways in cancer Glioma Prostate cancer Acute myeloid leukemia
1557981_at	0.358	4.118	3.542	2.900e-03	0.135	-1.551	RPS9	ribosomal protein S9	19	59396537	AK095055	6203	19q13.4	Hs.467284 Hs.546288	20	structural constituent of ribosome protein binding intracellular nucleolus cytoplasm cytosol ribosome translational elongation positive regulation of cell proliferation rRNA binding cytosolic small ribosomal subunit translation regulator activity	Ribosome
203267_s_at	-0.433	6.407	-3.542	2.903e-03	0.135	-1.552	DRG2	developmentally regulated GTP binding protein 2	17	17932007	BF223206	1819	17p11.2	Hs.78582	12	nucleotide binding GTP binding intracellular cytoplasm signal transduction
213251_at	-0.580	7.781	-3.540	2.914e-03	0.135	-1.556	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	AV712064	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
204524_at	-0.354	7.350	-3.539	2.922e-03	0.135	-1.558	PDPK1	3-phosphoinositide dependent protein kinase-1	16	2527970	NM_002613	5170	16p13.3	Hs.459691	103	nucleotide binding 3-phosphoinositide-dependent protein kinase activity protein binding ATP binding cytoplasm cytosol plasma membrane plasma membrane negative regulation of protein kinase activity intracellular signaling cascade transferase activity peptidyl-threonine phosphorylation actin cytoskeleton organization activation of protein kinase B activity cellular response to insulin stimulus regulation of establishment of protein localization	PPAR signaling pathway mTOR signaling pathway Focal adhesion Insulin signaling pathway Endometrial cancer Prostate cancer Non-small cell lung cancer
206662_at	-0.793	9.632	-3.538	2.925e-03	0.135	-1.559	GLRX	glutaredoxin (thioltransferase)	5	-95175308	NM_002064	2745	5q14	Hs.28988 Hs.712696	47	cytoplasm cytosol transport electron carrier activity protein disulfide oxidoreductase activity glutathione disulfide oxidoreductase activity electron transport chain cell redox homeostasis protein N-terminus binding
231950_at	0.580	4.964	3.538	2.926e-03	0.135	-1.559	ZNF658	zinc finger protein 658	9	-40761401	AW874634	26149	9p13.1	Hs.522147	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203002_at	-0.935	6.784	-3.537	2.931e-03	0.135	-1.561	AMOTL2	angiomotin like 2	3	-135556879	NM_016201	51421	3q21-q22	Hs.426312 Hs.713601	9	tight junction identical protein binding
226713_at	-0.413	6.527	-3.535	2.941e-03	0.136	-1.564	CCDC50	coiled-coil domain containing 50	3	192529567	AI247881	152137	3q28	Hs.478682	12	protein binding cytoplasm
209200_at	-0.893	10.422	-3.535	2.942e-03	0.136	-1.564	MEF2C	myocyte enhancer factor 2C	5	-88049814, -88049814	AL536517	4208	5q14	Hs.653394	56	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development negative regulation of specific transcription from RNA polymerase II promoter nuclear speck cell differentiation sequence-specific DNA binding positive regulation of survival gene product expression	MAPK signaling pathway
211456_x_at	-0.820	10.327	-3.535	2.943e-03	0.136	-1.565	MT1P2	metallothionein 1 pseudogene 2	1		AF333388	645745	1q43	Hs.632513	1
222443_s_at	-0.549	7.690	-3.534	2.951e-03	0.136	-1.567	RBM8A	RNA binding motif protein 8A	1	144218994	AF182415	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
1559315_s_at	0.359	2.890	3.533	2.953e-03	0.136	-1.568	LOC144481	hypothetical protein LOC144481	12		AK054607	144481	12q22	Hs.602278	1
224834_at	-0.581	6.627	-3.532	2.962e-03	0.136	-1.571	UBTD2	ubiquitin domain containing 2	5	-171569254	BF243404	92181	5q35.1	Hs.131570 Hs.716824	7	cytoplasm
202272_s_at	-0.449	7.031	-3.530	2.972e-03	0.136	-1.574	FBXO28	F-box protein 28	1	222368413	NM_015176	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
238124_at	-0.910	8.554	-3.530	2.976e-03	0.136	-1.575	MYOM3	myomesin family, member 3	1	-24255117	AI124053	127294	1p36.11	Hs.523413	4
214113_s_at	-0.656	7.575	-3.529	2.980e-03	0.136	-1.576	RBM8A	RNA binding motif protein 8A	1	144218994	AI738479	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
1562689_at	0.402	4.549	3.528	2.984e-03	0.136	-1.578	LOC151484	hypothetical protein LOC151484	2		BC043555	151484	2q37.1	Hs.559309	1
233517_s_at	0.424	5.630	3.527	2.991e-03	0.136	-1.579	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	AK021421	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
209019_s_at	-0.525	10.140	-3.527	2.992e-03	0.136	-1.580	PINK1	PTEN induced putative kinase 1	1	20832534	AF316873	65018	1p36	Hs.389171	105	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding mitochondrion mitochondrial outer membrane protein amino acid phosphorylation response to stress protein kinase cascade membrane integral to membrane transferase activity positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion	Parkinson's disease
226140_s_at	-2.017	7.548	-3.527	2.994e-03	0.136	-1.581	OTUD1	OTU domain containing 1	10	23768203	AI934347	220213	10p12.2	Hs.499042	4
235164_at	-0.623	6.484	-3.526	3.001e-03	0.136	-1.583	ZNF25	zinc finger protein 25	10	-38278800	BG433539	219749	10p11.1	Hs.499429	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202136_at	-0.379	9.463	-3.526	3.002e-03	0.136	-1.583	ZMYND11	zinc finger, MYND domain containing 11	10	170423, 170423	BE250417	10771	10p14	Hs.292265	17	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding nucleus cell cycle zinc ion binding cell proliferation regulation of transcription metal ion binding
218084_x_at	0.483	6.036	3.525	3.003e-03	0.136	-1.583	FXYD5	FXYD domain containing ion transport regulator 5	19	40337466	NM_014164	53827	19q12-q13.1	Hs.333418	20	actin binding ion channel activity ion transport membrane integral to membrane microvillus assembly cadherin binding negative regulation of calcium-dependent cell-cell adhesion
1556736_at	0.357	4.380	3.525	3.004e-03	0.136	-1.583	LOC100129858	hypothetical protein LOC100129858	4		AK095554	100129858	4q31.1	Hs.660477	1
205589_at	0.533	12.188	3.525	3.007e-03	0.136	-1.584	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	3	-46874360	NM_000258	4634	3p21.3-p21.2	Hs.517939	27	regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex regulation of striated muscle contraction structural constituent of muscle myosin complex A band I band myosin II heavy chain binding positive regulation of ATPase activity ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
204528_s_at	-0.557	8.114	-3.524	3.012e-03	0.137	-1.586	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	NM_004537	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
210611_s_at	-0.851	6.975	-3.523	3.019e-03	0.137	-1.588	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U26744	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
236866_at	0.476	4.787	3.523	3.020e-03	0.137	-1.588	GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase	16	-87407642	AA884446	2588	16q24.3	Hs.271383	39	N-acetylgalactosamine-4-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process N-acetylgalactosamine-6-sulfatase activity	Glycosaminoglycan degradation Metabolic pathways Lysosome
1553425_at	0.360	4.901	3.522	3.022e-03	0.137	-1.589	WDR65	WD repeat domain 65	1	43410612	NM_152498	149465	1p34.2	Hs.647644	6	membrane integral to membrane
217978_s_at	-0.396	7.870	-3.521	3.029e-03	0.137	-1.591	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	1	-152787674	NM_017582	55585	1q21.3	Hs.607928	7	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
204745_x_at	-0.709	8.513	-3.521	3.030e-03	0.137	-1.591	MT1G	metallothionein 1G	16	-55258153	NM_005950	4495	16q13	Hs.433391	17	copper ion binding protein binding zinc ion binding cadmium ion binding metal ion binding
205389_s_at	0.704	9.476	3.518	3.046e-03	0.137	-1.596	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	AI659683	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
214515_at	0.411	4.024	3.518	3.047e-03	0.137	-1.596	OR1E1	olfactory receptor, family 1, subfamily E, member 1	17	-3247509	NM_003553	8387	17p13.3	Hs.278485	7	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
209653_at	-0.899	5.423	-3.518	3.051e-03	0.137	-1.598	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	U93240	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
214073_at	-0.811	5.353	-3.517	3.052e-03	0.137	-1.598	CTTN	cortactin	11	69922259, 69922291	BG475299	2017	11q13	Hs.596164	106	ruffle protein binding soluble fraction cytoplasm cytoskeleton cell cortex lamellipodium	Tight junction Pathogenic Escherichia coli infection - EHEC
1554168_a_at	1.101	7.854	3.517	3.056e-03	0.137	-1.599	SH3KBP1	SH3-domain kinase binding protein 1	X	-19462003, -19462003	AF542051	30011	Xp22.1-p21.3	Hs.719268	58	molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse	Endocytosis
226603_at	-0.727	5.327	-3.514	3.077e-03	0.138	-1.606	SAMD9L	sterile alpha motif domain containing 9-like	7	-92597303	BE966604	219285	7q21.2	Hs.489118	4
222287_at	-0.763	11.343	-3.513	3.080e-03	0.138	-1.606	TRDN	triadin	6	-123579181	AW969675	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
219565_at	-0.509	5.331	-3.512	3.088e-03	0.138	-1.609	CYP20A1	cytochrome P450, family 20, subfamily A, polypeptide 1	2	203811408	NM_020674	57404	2q33.2	Hs.446065 Hs.707756	7	monooxygenase activity electron carrier activity membrane integral to membrane heme binding metal ion binding oxidation reduction
203149_at	-0.408	5.774	-3.511	3.096e-03	0.138	-1.611	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	19	50041232, 50041232	NM_002856	5819	19q13.2	Hs.655455	38	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of immunoglobulin mediated immune response plasma membrane cell-cell junction zonula adherens cell adhesion homophilic cell adhesion spermatid development cell surface coreceptor activity integral to membrane viral envelope fusion with host membrane positive regulation of mast cell activation susceptibility to natural killer cell mediated cytotoxicity virion attachment, binding of host cell surface coreceptor cell adhesion molecule binding adhesion to symbiont susceptibility to T cell mediated cytotoxicity	Cell adhesion molecules (CAMs) Adherens junction
1552791_a_at	-1.681	9.065	-3.511	3.097e-03	0.138	-1.611	TRDN	triadin	6	-123579181	NM_006073	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
244741_s_at	1.482	6.388	3.510	3.097e-03	0.138	-1.612	MGC9913	hypothetical protein MGC9913	19		BE855713	386759	19q13.43	Hs.23133	1
223429_x_at	-0.418	6.937	-3.510	3.102e-03	0.138	-1.613	ISY1	ISY1 splicing factor homolog (S. cerevisiae)	3	-130330924	BC004122	57461	3q21.3	Hs.512661	7	nucleus spliceosomal complex nucleolus cytoplasm mRNA processing RNA splicing
222725_s_at	-0.828	7.474	-3.510	3.103e-03	0.138	-1.613	PALMD	palmdelphin	1	99884018	AI082747	54873	1p22-p21	Hs.483993	7	cytoplasm regulation of cell shape membrane
218368_s_at	-1.078	7.033	-3.509	3.106e-03	0.139	-1.614	TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	16	3010313	NM_016639	51330	16p13.3	Hs.355899	25	angiogenesis ruffle receptor activity protein binding plasma membrane apoptosis cell motion substrate-bound cell migration, cell attachment to substrate cell adhesion multicellular organismal development cell death cell surface integral to membrane cell differentiation positive regulation of axon extension	Cytokine-cytokine receptor interaction
1554114_s_at	-0.742	4.607	-3.508	3.113e-03	0.139	-1.616	SSH2	slingshot homolog 2 (Drosophila)	17	-24977090	AB072359	85464	17q11.2	Hs.654754	11	actin binding protein tyrosine phosphatase activity cytoplasm cytoskeleton protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity actin cytoskeleton organization	Regulation of actin cytoskeleton
236320_at	0.426	3.883	3.507	3.120e-03	0.139	-1.618	CCDC17	coiled-coil domain containing 17	1	-45858302	AA010540	149483	1p34.1	Hs.18912	3
210993_s_at	-0.586	7.248	-3.505	3.130e-03	0.139	-1.621	SMAD1	SMAD family member 1	4	146622400, 146623406	U54826	4086	4q31	Hs.604588	118	MAPKKK cascade mesodermal cell fate commitment osteoblast fate commitment transcription factor activity RNA polymerase II transcription factor activity receptor signaling protein activity intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol inflammatory response signal transduction transforming growth factor beta receptor signaling pathway SMAD protein complex assembly gamete generation negative regulation of cell proliferation embryonic pattern specification positive regulation of gene expression integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity midbrain development hindbrain development primary microRNA processing homeostatic process identical protein binding positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter co-SMAD binding	TGF-beta signaling pathway
223615_at	0.414	6.230	3.505	3.135e-03	0.139	-1.623	ABI3	ABI family, member 3	17	44642587	AL136709	51225	17q21.3	Hs.130719	12	protein binding intracellular cytoplasm cell motion peptidyl-tyrosine phosphorylation lamellipodium regulation of cell migration
203100_s_at	-0.703	5.704	-3.504	3.136e-03	0.139	-1.623	CDYL	chromodomain protein, Y-like	6	4651391, 4721678, 4781330, 4835224	NM_004824	9425	6p25.1	Hs.269092	8	chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription
238615_at	0.317	2.866	3.504	3.137e-03	0.139	-1.623	ERLIN2	ER lipid raft associated 2	8	37713254, 37713254, 37713356	AI817403	11160	8p11.2	Hs.705490	13	molecular_function cytoplasm endoplasmic reticulum endoplasmic reticulum membrane biological_process membrane integral to membrane
228871_at	0.310	4.140	3.504	3.139e-03	0.139	-1.624	ALG14	asparagine-linked glycosylation 14 homolog (S. cerevisiae)	1	-95220866	AI652839	199857	1p21.3	Hs.408927	5	endoplasmic reticulum membrane integral to membrane	N-Glycan biosynthesis Metabolic pathways
238727_at	-0.734	3.259	-3.503	3.146e-03	0.139	-1.626	LOC440934	hypothetical LOC440934	2		AA031832	440934	2q36.1	Hs.715764	1
209105_at	-0.726	5.994	-3.502	3.150e-03	0.139	-1.627	NCOA1	nuclear receptor coactivator 1	2	24660849	AI672428	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
212131_at	-0.771	8.418	-3.501	3.160e-03	0.140	-1.630	LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)	19	39355191	BG054966	26065	19q13.11	Hs.718430	6
201075_s_at	-0.557	5.226	-3.499	3.172e-03	0.140	-1.633	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	3	-47602381	NM_003074	6599	3p23-p21	Hs.476179	39	chromatin DNA binding chromatin binding transcription coactivator activity intracellular nucleus nucleoplasm chromatin assembly or disassembly chromatin remodeling regulation of transcription from RNA polymerase II promoter protein C-terminus binding organ morphogenesis SWI/SNF complex regulation of transcription positive regulation of transcription, DNA-dependent protein N-terminus binding
202154_x_at	-0.633	7.366	-3.499	3.173e-03	0.140	-1.634	TUBB3	tubulin, beta 3	16	88517245	NM_006086	10381	16q24.3	Hs.511743	41	nucleotide binding GTPase activity structural molecule activity GTP binding intracellular microtubule microtubule-based movement mitosis neuron differentiation axon protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
219366_at	-0.797	6.794	-3.498	3.176e-03	0.140	-1.635	AVEN	apoptosis, caspase activation inhibitor	15	-31945719	NM_020371	57099	15q13.1	Hs.555966	10	protein binding intracellular membrane fraction apoptosis anti-apoptosis membrane
237515_at	-1.642	6.341	-3.497	3.181e-03	0.140	-1.636	TMEM56	transmembrane protein 56	1	95355481	AA054642	148534	1p21.3	Hs.483512	3	molecular_function cellular_component biological_process membrane integral to membrane
228155_at	1.079	9.301	3.495	3.196e-03	0.141	-1.640	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	BF512388	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
229963_at	0.555	3.927	3.495	3.199e-03	0.141	-1.641	BEX5	brain expressed, X-linked 5	X	-101295335, -101295335	AV726956	340542	Xq22.1	Hs.47209	5	cytoplasm
1564490_at	0.379	4.663	3.494	3.205e-03	0.141	-1.643	LOC100128830	hypothetical protein LOC100128830	10		AK097584	100128830	10q26.3	Hs.638406	1
225919_s_at	-0.515	5.703	-3.494	3.207e-03	0.141	-1.644	C9orf72	chromosome 9 open reading frame 72	9	-27550498, -27536543	AI832598	203228	9p21.2	Hs.493639	4
201297_s_at	-0.742	5.545	-3.493	3.212e-03	0.141	-1.645	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	2	-74236718	AK023321	55233	2p13.1	Hs.196437	12	protein binding zinc ion binding metal ion binding
215016_x_at	-0.371	10.701	-3.492	3.216e-03	0.141	-1.646	DST	dystonin	6	-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743	BC004912	667	6p12.1	Hs.631992 Hs.669931	48	actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding
1567214_a_at	-0.576	6.760	-3.492	3.217e-03	0.141	-1.646	PNN	pinin, desmosome associated protein	14	38714137	U59479	5411	14q21.1	Hs.409965	30	DNA binding structural molecule activity protein binding nucleus spliceosomal complex nucleolus cytoplasm intermediate filament plasma membrane mRNA processing cell adhesion RNA splicing nuclear speck desmosome regulation of transcription
208786_s_at	-0.723	9.127	-3.492	3.220e-03	0.141	-1.647	MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	16	85983301	AF183417	81631	16q24.2	Hs.356061	22	protein binding intracellular cytoplasm autophagic vacuole microtubule autophagy modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
200794_x_at	-0.755	9.386	-3.491	3.227e-03	0.141	-1.649	DAZAP2	DAZ associated protein 2	12	49918774, 49918774	NM_014764	9802	12q12	Hs.369761	15	protein binding WW domain binding
225378_at	-0.859	6.877	-3.489	3.235e-03	0.141	-1.651	VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)	8	17148771	AI866426	137492	8p22	Hs.343873 Hs.512464	8	nucleus endosome protein transport membrane	Endocytosis
202577_s_at	-0.571	6.353	-3.489	3.236e-03	0.141	-1.652	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A	16	68938324	BC005162	55308	16q22.1	Hs.656037	5	nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport
210711_at	0.342	4.589	3.489	3.236e-03	0.141	-1.652	C1orf217	chromosome 1 open reading frame 217	1		BC000988	84719	1q32.1	Hs.661178	1
229044_at	0.411	5.806	3.489	3.238e-03	0.141	-1.652	NUDT17	nudix (nucleoside diphosphate linked moiety X)-type motif 17	1	-144297851	AA284522	200035	1q21.1	Hs.585066	4	magnesium ion binding mitochondrion hydrolase activity manganese ion binding
218092_s_at	-0.563	5.228	-3.489	3.240e-03	0.141	-1.653	AGFG1	ArfGAP with FG repeats 1	2	228045131	NM_004504	3267	2q36.3	Hs.352962	29	DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding
226060_at	-0.487	4.822	-3.487	3.250e-03	0.141	-1.656	RFT1	RFT1 homolog (S. cerevisiae)	3	-53097542	BF475369	91869	3p21.1	Hs.631910	3	lipid transporter activity lipid transport carbohydrate transport membrane integral to membrane	N-Glycan biosynthesis
210285_x_at	-0.497	7.560	-3.487	3.250e-03	0.141	-1.656	WTAP	Wilms tumor 1 associated protein	6	160068141, 160068141, 160068609	BC000383	9589	6q25-q27	Hs.446091 Hs.710715	16	nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane
219643_at	-2.569	5.193	-3.487	3.251e-03	0.141	-1.656	LRP1B	low density lipoprotein-related protein 1B (deleted in tumors)	2	-140705465	NM_018557	53353	2q21.2	Hs.656461	14	receptor activity low-density lipoprotein receptor activity calcium ion binding protein binding membrane fraction receptor-mediated endocytosis protein transport membrane integral to membrane
218078_s_at	-0.554	6.491	-3.484	3.269e-03	0.142	-1.661	ZDHHC3	zinc finger, DHHC-type containing 3	3	-44931757	NM_016598	51304	3p21.31	Hs.61430	8	Golgi apparatus zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
218729_at	0.744	6.757	3.482	3.286e-03	0.142	-1.666	LXN	latexin	3	-159866896	NM_020169	56925	3q25.32	Hs.478067	5	enzyme inhibitor activity protein binding cytoplasm metalloendopeptidase inhibitor activity detection of temperature stimulus involved in sensory perception of pain
208136_s_at	0.414	5.683	3.482	3.287e-03	0.142	-1.666	MGC3771	hypothetical LOC81854	16	-3100462	NM_030970	81854	16p13.3	Hs.669490	1
224697_at	-0.436	5.988	-3.479	3.307e-03	0.142	-1.672	DCAF5	DDB1 and CUL4 associated factor 5	14	-68587390	AI568478	8816	14q23-q24.1	Hs.509780	6
201993_x_at	-0.410	8.794	-3.478	3.309e-03	0.142	-1.672	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	NM_005463	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
1557227_s_at	-0.414	3.072	-3.477	3.317e-03	0.143	-1.674	TPR	translocated promoter region (to activated MET oncogene)	1	-184547408	AW235355	7175	1q25	Hs.279640	30	nucleotide binding kinetochore serine-tRNA ligase activity protein binding ATP binding nucleus nuclear pore nucleoplasm cytoplasm translation seryl-tRNA aminoacylation protein import into nucleus mitotic cell cycle spindle assembly checkpoint protein transport membrane mRNA transport intracellular protein transmembrane transport	Pathways in cancer Thyroid cancer
220238_s_at	-0.459	3.260	-3.477	3.319e-03	0.143	-1.675	KLHL7	kelch-like 7 (Drosophila)	7	23111877	NM_018846	55975	7p15.3	Hs.654817	9	protein binding nucleus nucleolus
212771_at	-0.929	6.405	-3.477	3.320e-03	0.143	-1.675	FAM171A1	family with sequence similarity 171, member A1	10	-15293649	AU150943	221061	10p13	Hs.66762	4	membrane integral to membrane
237145_at	-0.427	2.934	-3.476	3.328e-03	0.143	-1.677	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	15	38013638	AI953362	440275	15q15.1	Hs.656673	10	nucleotide binding eukaryotic translation initiation factor 2alpha kinase activity aminoacyl-tRNA ligase activity protein binding ATP binding intracellular cytoplasm tRNA aminoacylation for protein translation regulation of translational initiation protein amino acid phosphorylation transferase activity cytosolic ribosome
205595_at	0.379	5.158	3.474	3.336e-03	0.143	-1.680	DSG3	desmoglein 3 (pemphigus vulgaris antigen)	18	27281729	NM_001944	1830	18q12.1-q12.2	Hs.1925	51	calcium ion binding protein binding cytosol plasma membrane plasma membrane cell adhesion homophilic cell adhesion integral to membrane cell junction desmosome
205694_at	-2.076	6.660	-3.473	3.347e-03	0.143	-1.683	TYRP1	tyrosinase-related protein 1	9	12683385	NM_000550	7306	9p23	Hs.270279	49	copper ion binding protein binding membrane integral to membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen melanocyte differentiation melanosome organization melanosome membrane melanin biosynthetic process protein homodimerization activity acetoacetic acid metabolic process pigmentation metal ion binding protein heterodimerization activity oxidation reduction	Tyrosine metabolism Metabolic pathways Melanogenesis
217591_at	-0.867	5.835	-3.472	3.355e-03	0.144	-1.685	SKIL	SKI-like oncogene	3	171558166, 171560104	BF725121	6498	3q26	Hs.581632	34	nucleotide binding transcription corepressor activity transforming growth factor beta receptor, cytoplasmic mediator activity protein binding nucleus transcription from RNA polymerase II promoter signal transduction multicellular organismal development
227123_at	0.392	3.818	3.472	3.355e-03	0.144	-1.685	RAB3B	RAB3B, member RAS oncogene family	1	-52157422	AU156710	5865	1p32-p31	Hs.123072	15	nucleotide binding GTPase activity protein binding GTP binding plasma membrane small GTPase mediated signal transduction synaptic vesicle protein transport regulation of exocytosis peptidyl-cysteine methylation	Tight junction
206254_at	-1.216	7.646	-3.471	3.360e-03	0.144	-1.686	EGF	epidermal growth factor (beta-urogastrone)	4	111053488	NM_001963	1950	4q25	Hs.419815	289	activation of MAPKK activity angiogenesis epidermal growth factor receptor binding calcium ion binding protein binding extracellular region extracellular space plasma membrane DNA replication signal transduction epidermal growth factor receptor signaling pathway growth factor activity integral to membrane positive regulation of granule cell precursor proliferation transmembrane receptor protein tyrosine kinase activator activity platelet alpha granule lumen positive regulation of phosphorylation positive regulation of MAP kinase activity positive regulation of epidermal growth factor receptor activity positive regulation of mitosis branching morphogenesis of a tube regulation of protein secretion regulation of peptidyl-tyrosine phosphorylation negative regulation of secretion	MAPK signaling pathway ErbB signaling pathway Cytokine-cytokine receptor interaction Endocytosis Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Non-small cell lung cancer
1555487_a_at	-0.327	5.670	-3.471	3.360e-03	0.144	-1.686	ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)	7	152087783	BC015207	57180	7q36.1	Hs.647117	8	nucleotide binding actin binding protein binding ATP binding cytoplasm cytoskeleton regulation of actin filament polymerization cell projection
1558093_s_at	-0.856	5.991	-3.470	3.364e-03	0.144	-1.687	MATR3	matrin 3	5	138637690, 138657253	BI832461	9782	5q31.2	Hs.268939	24	nucleotide binding RNA binding structural molecule activity protein binding intracellular nucleus nuclear inner membrane zinc ion binding nuclear matrix metal ion binding
223466_x_at	-0.653	6.617	-3.469	3.371e-03	0.144	-1.689	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	5	-74702683, -74702683	BC000102	10087	5q13.3	Hs.270437	26	protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response
201544_x_at	-0.398	9.087	-3.469	3.372e-03	0.144	-1.690	PABPN1	poly(A) binding protein, nuclear 1	14	22859236	BF675004	8106	14q11.2-q13	Hs.707712	42	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm muscle contraction poly(A)+ mRNA export from nucleus
210140_at	0.423	5.489	3.468	3.383e-03	0.144	-1.692	CST7	cystatin F (leukocystatin)	20	24877865	AF031824	8530	20p11.21	Hs.143212	17	cysteine-type endopeptidase inhibitor activity extracellular region cytoplasm immune response
236613_at	-0.638	4.330	-3.465	3.401e-03	0.144	-1.697	RBM25	RNA binding motif protein 25	14	72594973	BE466195	58517	14q24.3	Hs.531106	13	nucleotide binding nuclear mRNA splicing, via spliceosome nucleic acid binding mRNA binding cellular_component nucleus cytoplasm nuclear speck
217834_s_at	-0.651	6.533	-3.464	3.407e-03	0.144	-1.699	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	NM_006372	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
235634_at	0.435	5.179	3.464	3.407e-03	0.144	-1.699	PURG	purine-rich element binding protein G	8	-31007898, -30972862	BE503391	29942	8p11	Hs.373778	3	DNA binding nucleus
221066_at	0.347	3.359	3.464	3.410e-03	0.144	-1.700	RXFP3	relaxin/insulin-like family peptide receptor 3	5	33972247	NM_016568	51289	5p15.1-p14	Hs.170146	11	receptor activity N-formyl peptide receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
208842_s_at	-0.417	7.657	-3.463	3.416e-03	0.144	-1.701	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	W93787	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
35147_at	0.570	6.873	3.463	3.416e-03	0.144	-1.701	MCF2L	MCF.2 cell line derived transforming sequence-like	13	112670757, 112681655	AB002360	23263	13q34	Hs.170422 Hs.597691	15	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm mitochondrion plasma membrane intracellular signaling cascade regulation of Rho protein signal transduction
218154_at	0.370	6.445	3.462	3.422e-03	0.144	-1.703	GSDMD	gasdermin D	8	144711634	NM_024736	79792	8q24.3	Hs.118983	8	cellular response to extracellular stimulus
208579_x_at	-0.552	5.642	-3.462	3.424e-03	0.144	-1.703	H2BFS	H2B histone family, member S	21		NM_017445	54145	21q22.3	Hs.473961	17	nucleosome DNA binding nucleus chromosome nucleosome assembly defense response to bacterium
204407_at	-0.998	3.787	-3.462	3.426e-03	0.144	-1.704	TTF2	transcription termination factor, RNA polymerase II	1	117404471	AF080255	8458	1p22	Hs.486818	12	nucleotide binding DNA binding RNA polymerase II transcription termination factor activity helicase activity ATP binding nucleus spliceosomal complex cytoplasm transcription termination mRNA processing transcription elongation factor complex ATP-dependent helicase activity DNA-dependent ATPase activity zinc ion binding RNA splicing hydrolase activity regulation of transcription
201133_s_at	-0.646	8.032	-3.461	3.433e-03	0.145	-1.706	PJA2	praja ring finger 2	5	-108698308	AA142966	9867	5q21.3	Hs.483036 Hs.592564	10	protein binding cytoplasm endoplasmic reticulum Golgi apparatus plasma membrane zinc ion binding postsynaptic density ligase activity modification-dependent protein catabolic process cell junction synapse postsynaptic membrane metal ion binding
218270_at	0.441	9.273	3.460	3.435e-03	0.145	-1.706	MRPL24	mitochondrial ribosomal protein L24	1	-154973717	NM_024540	79590	1q21-q22	Hs.418233	9	structural constituent of ribosome intracellular mitochondrion ribosome translation
211954_s_at	-0.383	9.184	-3.459	3.444e-03	0.145	-1.709	IPO5	importin 5	13	97403929	BC000947	3843	13q32.2	Hs.712598	53	protein import into nucleus, docking GTPase inhibitor activity protein binding nucleus nuclear pore nucleolus cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport Ran GTPase binding protein transporter activity interspecies interaction between organisms
201376_s_at	-0.436	6.523	-3.459	3.444e-03	0.145	-1.709	HNRNPF	heterogeneous nuclear ribonucleoprotein F	10	-43201070, -43201070, -43201070, -43201070, -43201070, -43201070	AI591354	3185	10q11.21-q11.22	Hs.712955 Hs.808	30	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm heterogeneous nuclear ribonucleoprotein complex regulation of RNA splicing
206544_x_at	-0.881	7.914	-3.459	3.448e-03	0.145	-1.710	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	NM_003070	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
228559_at	-0.529	3.871	-3.457	3.455e-03	0.145	-1.712	CENPN	centromere protein N	16	79597603, 79597603, 79597603	BF111626	55839	16q23.2	Hs.55028	9	chromosome, centromeric region condensed chromosome kinetochore nucleus chromosome
201227_s_at	0.444	10.740	3.457	3.459e-03	0.145	-1.713	NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	10	-102273486	NM_005004	4714	10q23.2-q23.33	Hs.523215	16	NADH dehydrogenase activity mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I endoplasmic reticulum mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1555372_at	0.687	5.773	3.455	3.472e-03	0.145	-1.716	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2	111594961, 111594961	AF455755	10018	2q13	Hs.469658	143	peripheral to membrane of membrane fraction in utero embryonic development B cell homeostasis B cell apoptosis kidney development myeloid cell homeostasis protein binding cytoplasm mitochondrion mitochondrial outer membrane cytosol plasma membrane induction of apoptosis cell-matrix adhesion spermatogenesis microtubule binding male gonad development activation of pro-apoptotic gene products post-embryonic development mammary gland development tube lumen formation odontogenesis of dentine-containing tooth T cell homeostasis ear development regulation of organ growth regulation of pigmentation during development spleen development thymus development post-embryonic organ morphogenesis
232000_at	-0.889	3.038	-3.454	3.477e-03	0.145	-1.717	TTC39B	tetratricopeptide repeat domain 39B	9	-15161560	AW001030	158219	9p22.3	Hs.563630	3	binding
1558233_s_at	-0.577	7.094	-3.451	3.504e-03	0.146	-1.725	ATF1	activating transcription factor 1	12	49444085	CA337502	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
224642_at	-1.181	7.117	-3.451	3.505e-03	0.146	-1.725	FYTTD1	forty-two-three domain containing 1	3	198960820, 198961020, 198961657	BG291550	84248	3q29	Hs.277533	6
1556203_a_at	0.413	3.932	3.448	3.524e-03	0.147	-1.730	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	1	204582822, 204582822	AI263819	23380	1q32.1	Hs.497575	7	GTPase activator activity intracellular signal transduction	Axon guidance
226615_at	-0.563	6.555	-3.443	3.561e-03	0.148	-1.740	XPR1	xenotropic and polytropic retrovirus receptor	1	178867768	BE439489	9213	1q25.1	Hs.227656	6	G-protein coupled receptor activity plasma membrane integral to plasma membrane G-protein coupled receptor protein signaling pathway
218999_at	-0.927	7.217	-3.442	3.564e-03	0.148	-1.740	TMEM140	transmembrane protein 140	7	134483363	NM_018295	55281	7q33	Hs.719309	8	membrane integral to membrane
1554806_a_at	-0.545	6.320	-3.442	3.565e-03	0.148	-1.741	FBXO8	F-box protein 8	4	-175394384	BC040456	26269	4q34.1	Hs.76917	9	ubiquitin ligase complex ARF guanyl-nucleotide exchange factor activity intracellular ubiquitin-dependent protein catabolic process regulation of ARF protein signal transduction
222033_s_at	0.441	7.332	3.442	3.566e-03	0.148	-1.741	FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	13	-27871181, -27857687, -27840233, -27772482	AA058828	2321	13q12	Hs.654360	228	nucleotide binding patterning of blood vessels receptor activity vascular endothelial growth factor receptor activity ATP binding extracellular region extracellular space cytoplasm plasma membrane plasma membrane integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway multicellular organismal development female pregnancy positive regulation of cell proliferation cell migration transferase activity growth factor binding cell differentiation positive regulation of vascular endothelial growth factor receptor signaling pathway identical protein binding	Cytokine-cytokine receptor interaction Endocytosis Focal adhesion
223519_at	-0.812	9.964	-3.442	3.566e-03	0.148	-1.741	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AW069181	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
222235_s_at	-0.653	6.103	-3.440	3.586e-03	0.148	-1.746	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	10	42953939	AL139812	55454	10q11.21	Hs.657569	6	protein binding Golgi apparatus membrane integral to membrane transferase activity integral to Golgi membrane Golgi cisterna membrane metal ion binding glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Chondroitin sulfate biosynthesis Metabolic pathways
211761_s_at	-0.440	9.436	-3.439	3.590e-03	0.148	-1.747	CACYBP	calcyclin binding protein	1	173235193, 173235514	BC005975	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
222919_at	-0.620	12.085	-3.438	3.598e-03	0.148	-1.749	TRDN	triadin	6	-123579181	AA192306	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
206853_s_at	-0.410	6.486	-3.436	3.610e-03	0.149	-1.752	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AL121964	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
200924_s_at	-0.498	6.644	-3.434	3.629e-03	0.149	-1.757	SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	11	62380093, 62404862	NM_002394	6520	11q13	Hs.502769	74	catalytic activity calcium:sodium antiporter activity protein binding protein binding plasma membrane carbohydrate metabolic process transport calcium ion transport amino acid transport cell surface neutral amino acid transmembrane transporter activity tryptophan transport integral to membrane cell growth melanosome cation binding leucine import
223082_at	1.047	8.513	3.433	3.635e-03	0.150	-1.758	SH3KBP1	SH3-domain kinase binding protein 1	X	-19462003, -19462003	AF230904	30011	Xp22.1-p21.3	Hs.719268	58	molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse	Endocytosis
226580_at	-0.533	7.477	-3.430	3.655e-03	0.150	-1.763	BRMS1L	breast cancer metastasis-suppressor 1-like	14	35365347	AA779684	84312	14q13.2	Hs.525299	3	nucleus regulation of growth regulation of transcription
212554_at	-0.472	11.653	-3.430	3.656e-03	0.150	-1.763	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6	17501714	N90755	10486	6p22.3	Hs.132902	7	actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity
226277_at	-0.559	7.980	-3.429	3.664e-03	0.150	-1.766	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	5	-74702683, -74702683	AA889952	10087	5q13.3	Hs.270437	26	protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response
207397_s_at	0.363	3.123	3.428	3.674e-03	0.150	-1.768	HOXD13	homeobox D13	2	176665777	NM_000523	3239	2q31.1	Hs.152414	37	skeletal system development transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter multicellular organismal development sequence-specific DNA binding
209207_s_at	-0.555	6.153	-3.427	3.676e-03	0.150	-1.769	SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae)	1	143807763	BC001364	9554	1q21.1	Hs.632438 Hs.715002	13	protein binding endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus ER to Golgi vesicle-mediated transport protein transport membrane integral to membrane vesicle-mediated transport melanosome	SNARE interactions in vesicular transport
209770_at	0.608	5.674	3.427	3.682e-03	0.150	-1.770	BTN3A1	butyrophilin, subfamily 3, member A1	6	26510443	U90552	11119	6p22.1	Hs.191510 Hs.628564	10	lipid metabolic process membrane integral to membrane
1553422_s_at	-0.509	9.039	-3.427	3.683e-03	0.150	-1.770	A2BP1	ataxin 2-binding protein 1	16	6009132, 6763810, 7322751	NM_145892	54715	16p13.3	Hs.459842	22	nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport
213086_s_at	-0.705	8.418	-3.426	3.684e-03	0.150	-1.771	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	BF341845	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
201245_s_at	-0.501	7.079	-3.426	3.685e-03	0.150	-1.771	OTUB1	OTU domain, ubiquitin aldehyde binding 1	11	63509900	AL523776	55611	11q13.1	Hs.473788	15	immune response peptidase activity cysteine-type peptidase activity modification-dependent protein catabolic process
213592_at	0.738	6.462	3.426	3.686e-03	0.150	-1.771	APLNR	apelin receptor	11	-56757629	X89271	187	11q12	Hs.438311	29	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway	Neuroactive ligand-receptor interaction
202467_s_at	-0.674	9.905	-3.425	3.692e-03	0.150	-1.773	COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	15	-47204762	NM_004236	9318	15q21.2	Hs.369614	37	signal transducer activity protein binding protein binding nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter signal transduction signalosome
205757_at	0.344	4.339	3.425	3.695e-03	0.150	-1.773	ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	14	-73502935	NM_001249	957	14q24	Hs.131555	14	magnesium ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen hydrolase activity nucleoside-diphosphatase activity	Purine metabolism Pyrimidine metabolism
218168_s_at	-0.587	11.345	-3.424	3.704e-03	0.150	-1.776	CABC1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	1	225194560	NM_020247	56997	1q42.13	Hs.118241	10	nucleotide binding ATP binding mitochondrion cell death kinase activity transferase activity
240509_s_at	-0.620	2.488	-3.423	3.712e-03	0.151	-1.777	GREM2	gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)	1	-238719495	BF064262	64388	1q43	Hs.98206	9	cytokine activity extracellular region extracellular region extracellular space BMP signaling pathway
202733_at	-0.598	6.211	-3.420	3.734e-03	0.151	-1.783	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	5	-131556204, -131556202, -131556202	NM_004199	8974	5q31	Hs.519568	14	procollagen-proline 4-dioxygenase activity iron ion binding protein binding endoplasmic reticulum endoplasmic reticulum lumen electron carrier activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen peptidyl-proline hydroxylation to 4-hydroxy-L-proline L-ascorbic acid binding metal ion binding oxidation reduction	Arginine and proline metabolism Metabolic pathways
1555971_s_at	-0.500	7.134	-3.420	3.735e-03	0.151	-1.783	FBXO28	F-box protein 28	1	222368413	AU154086	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
1556190_s_at	-0.464	3.310	-3.418	3.749e-03	0.151	-1.786	PRNP	prion protein	20	4614796, 4615156	AK056897	5621	20p13	Hs.472010 Hs.610285 Hs.707152 Hs.714553	353	copper ion binding cytoplasm endoplasmic reticulum Golgi apparatus plasma membrane cellular copper ion homeostasis anti-apoptosis response to oxidative stress microtubule binding metabolic process extrinsic to membrane anchored to membrane identical protein binding membrane raft response to cadmium ion response to copper ion protein homooligomerization	Prion diseases
235388_at	-1.127	4.400	-3.417	3.753e-03	0.151	-1.787	CHD9	chromodomain helicase DNA binding protein 9	16	51646445	BG538482	80205	16q12.2	Hs.59159 Hs.622347	10	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription
222396_at	-1.217	8.041	-3.417	3.756e-03	0.151	-1.788	HN1	hematological and neurological expressed 1	17	-70642938, -70642938	AF060925	51155	17q25.1	Hs.532803 Hs.713826	9	nucleus
225578_at	-0.826	7.671	-3.416	3.763e-03	0.151	-1.790	C13orf37	chromosome 13 open reading frame 37	13	-72180495	AI885466	440145	13q21.33-q22.1	Hs.28465	1
217165_x_at	-0.753	8.412	-3.416	3.764e-03	0.151	-1.790	MT1F	metallothionein 1F	16	55249355	M10943	4494	16q13	Hs.513626	20	copper ion binding cytoplasm biological_process zinc ion binding cadmium ion binding metal ion binding
214844_s_at	-0.717	9.310	-3.416	3.765e-03	0.151	-1.790	DOK5	docking protein 5	20	52525672	AL050069	55816	20q13.2	Hs.656582	10	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
226678_at	0.463	6.434	3.415	3.769e-03	0.151	-1.791	UNC13D	unc-13 homolog D (C. elegans)	17	-71334901	BG054744	201294	17q25.1	Hs.41045	21	granuloma formation germinal center formation cytoplasm exocytosis phagocytosis membrane natural killer cell degranulation defense response to virus
205951_at	-2.367	11.141	-3.415	3.772e-03	0.151	-1.792	MYH1	myosin, heavy chain 1, skeletal muscle, adult	17	-10336348	NM_005963	4619	17p13.1	Hs.689619	30	nucleotide binding motor activity actin binding calmodulin binding ATP binding nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction myosin complex myofibril A band	Tight junction
218025_s_at	0.543	10.491	3.415	3.773e-03	0.151	-1.793	PECI	peroxisomal D3,D2-enoyl-CoA isomerase	6	-4060925	NM_006117	10455	6p24.3	Hs.15250	15	acyl-CoA binding dodecenoyl-CoA delta-isomerase activity binding peroxisome peroxisomal matrix fatty acid metabolic process metabolic process isomerase activity	Fatty acid metabolism
228725_x_at	-0.428	6.179	-3.414	3.776e-03	0.151	-1.793	PRMT2	protein arginine methyltransferase 2	21	46879954	BF003112	3275	21q22.3	Hs.154163	17	signal transducer activity nucleus protein amino acid methylation signal transduction methyltransferase activity transferase activity identical protein binding
203914_x_at	-0.815	5.134	-3.413	3.786e-03	0.152	-1.796	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	4	-175647902, -175647902	NM_000860	3248	4q34-q35	Hs.596913	47	prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction
227022_at	-0.714	5.800	-3.413	3.786e-03	0.152	-1.796	GNPDA2	glucosamine-6-phosphate deaminase 2	4	-44398924	AI817388	132789	4p12	Hs.21398	6	glucosamine-6-phosphate deaminase activity cytoplasm carbohydrate metabolic process N-acetylglucosamine metabolic process hydrolase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
226353_at	-0.815	8.706	-3.412	3.797e-03	0.152	-1.798	SPPL2A	signal peptide peptidase-like 2A	15	-48787028	AI674647	84888	15q21.2	Hs.401537	12	aspartic-type endopeptidase activity peptidase activity membrane integral to membrane
228593_at	0.347	6.091	3.412	3.798e-03	0.152	-1.798	MTMR9L	myotubularin related protein 9-like	1	-32469848	AI271425	339483	1p35.1	Hs.471067	3
225793_at	-0.582	7.860	-3.411	3.801e-03	0.152	-1.799	LIX1L	Lix1 homolog (mouse)-like	1	144188441	AW500180	128077	1q21.1	Hs.632435	2
201351_s_at	-0.594	8.669	-3.411	3.802e-03	0.152	-1.800	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AF070656	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
213554_s_at	-0.484	6.317	-3.411	3.806e-03	0.152	-1.800	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	AI928407	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
203906_at	0.448	7.755	3.410	3.807e-03	0.152	-1.801	IQSEC1	IQ motif and Sec7 domain 1	3	-12913718, -12913718	AI652645	9922	3p25.2	Hs.475506	10	ARF guanyl-nucleotide exchange factor activity intracellular nucleus cytoplasm regulation of ARF protein signal transduction	Endocytosis
232740_at	0.371	2.920	3.409	3.816e-03	0.152	-1.803	MCM3APAS	MCM3AP antisense RNA (non-protein coding)	21	46473585	BC002458	114044	21q22.3	Hs.709346	3
224367_at	2.900	6.783	3.408	3.823e-03	0.152	-1.805	BEX2	brain expressed X-linked 2	X	-102450929	AF251053	84707	Xq22	Hs.398989	11	nucleus cytoplasm
1554415_at	-0.717	4.626	-3.408	3.828e-03	0.152	-1.806	TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	1	-227801563, -227795486	BC041094	27097	1q42.13	Hs.270621	16	transcription factor activity transcription coactivator activity histone acetyltransferase activity nucleus transcription from RNA polymerase II promoter STAGA complex transcription factor TFTC complex histone H3 acetylation regulation of transcription	Basal transcription factors
206833_s_at	-0.678	10.363	-3.407	3.834e-03	0.152	-1.807	ACYP2	acylphosphatase 2, muscle type	2	54195913	NM_001108	98	2p16.2	Hs.516173 Hs.642983	16	acylphosphatase activity phosphate metabolic process hydrolase activity	Pyruvate metabolism Benzoate degradation via CoA ligation
222868_s_at	0.501	4.697	3.407	3.834e-03	0.152	-1.807	IL18BP	interleukin 18 binding protein	11	71387605, 71387756, 71388310, 71388620	AI521549	10068	11q13	Hs.591967	22	extracellular region interleukin-18 binding T-helper 1 type immune response receptor antagonist activity
220254_at	-0.603	3.707	-3.406	3.840e-03	0.152	-1.809	LRP12	low density lipoprotein-related protein 12	8	-105570642	NM_013437	29967	8q22.2-q23.1	Hs.600630	8	receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth
211746_x_at	-0.286	10.723	-3.406	3.841e-03	0.152	-1.809	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	11	-14492087, -14482998, -14482998	BC005932	5682	11p15.1	Hs.102798 Hs.445711	52	RNA binding threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex polysome ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
1556228_a_at	-0.463	5.248	-3.406	3.844e-03	0.152	-1.810	VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	8	-67705041	AF088033	80124	8q13	Hs.632066	16	ubiquitin-specific protease activity cytoplasm endoplasmic reticulum Golgi apparatus Golgi stack peptidase activity cysteine-type peptidase activity protein ubiquitination modification-dependent protein catabolic process
224932_at	0.612	11.130	3.406	3.846e-03	0.152	-1.810	CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10	22	-22438020	AI814909	400916	22q11.23	Hs.66915	2	mitochondrion
238890_at	-0.625	5.500	-3.403	3.864e-03	0.153	-1.814	PSMG1	proteasome (prosome, macropain) assembly chaperone 1	21	-39469253	AI791303	8624	21q22.3	Hs.473838	12	protein binding cytoplasm endoplasmic reticulum proteasome assembly
223021_x_at	-0.776	7.356	-3.403	3.866e-03	0.153	-1.815	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	BF241590	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
219165_at	1.019	8.954	3.403	3.866e-03	0.153	-1.815	PDLIM2	PDZ and LIM domain 2 (mystique)	8	22492587, 22493928, 22493928	NM_021630	64236	8p21.2	Hs.632034	10	protein binding nucleus cytoplasm cytoskeleton zinc ion binding cell surface metal ion binding
208669_s_at	-0.435	9.563	-3.403	3.869e-03	0.153	-1.816	EID1	EP300 interacting inhibitor of differentiation 1	15	46957581	AF109873	23741	15q21.1-q21.2	Hs.255973 Hs.714048	12	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding cellular_component nucleus cytoplasm cell cycle specific transcriptional repressor activity cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of transcription
200720_s_at	-0.516	7.918	-3.402	3.874e-03	0.153	-1.817	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	10	-104228976	AL532341	10121	10q24.32	Hs.153961	26	nucleotide binding protein binding ATP binding cytoplasm centrosome cytoskeleton dynactin complex vesicle-mediated transport
232932_at	0.425	5.416	3.402	3.877e-03	0.153	-1.817	LOC645030	hypothetical protein LOC645030	1		AU145140	645030	1p31.3	Hs.632410
212599_at	-0.923	6.733	-3.401	3.884e-03	0.153	-1.819	AUTS2	autism susceptibility candidate 2	7	68701840, 68701841, 68701841	AK025298	26053	7q11.22	Hs.654801 Hs.712991	13	molecular_function cellular_component biological_process
205173_x_at	-0.523	6.740	-3.399	3.897e-03	0.153	-1.822	CD58	CD58 molecule	1	-116862845, -116858679	NM_001779	965	1p13	Hs.34341	38	protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane	Cell adhesion molecules (CAMs)
1569351_at	0.327	4.829	3.399	3.897e-03	0.153	-1.822	SOBP	sine oculis binding protein homolog (Drosophila)	6	107918009	BC014859	55084	6q21	Hs.445244	4	zinc ion binding metal ion binding
203662_s_at	-0.700	9.137	-3.399	3.898e-03	0.153	-1.822	TMOD1	tropomodulin 1	9	99326257	NM_003275	7111	9q22.3	Hs.494595	18	actin binding tropomyosin binding nucleus cytoplasm membrane myofibril myofibril assembly cortical cytoskeleton
212032_s_at	-0.542	7.334	-3.399	3.901e-03	0.153	-1.823	PTOV1	prostate tumor overexpressed 1	19	55046227	AL046054	53635	19q13.33	Hs.587979	11	nucleus cytoplasm plasma membrane regulation of transcription perinuclear region of cytoplasm
214646_at	0.336	4.847	3.398	3.907e-03	0.153	-1.824	HIST1H3J	histone cluster 1, H3j	6	-27966071	AL522145	8356	6p22-p21.3	Hs.484990	8		Systemic lupus erythematosus
204142_at	-0.895	6.051	-3.398	3.910e-03	0.153	-1.825	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	NM_017512	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
1556209_at	-1.256	4.095	-3.397	3.917e-03	0.153	-1.827	CLEC2B	C-type lectin domain family 2, member B	12	-9896234	CA447397	9976	12p13-p12	Hs.85201	10	binding sugar binding integral to plasma membrane membrane
213476_x_at	-0.810	7.695	-3.396	3.919e-03	0.153	-1.827	TUBB3	tubulin, beta 3	16	88517245	AL565749	10381	16q24.3	Hs.511743	41	nucleotide binding GTPase activity structural molecule activity GTP binding intracellular microtubule microtubule-based movement mitosis neuron differentiation axon protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
224628_at	-0.400	8.307	-3.395	3.928e-03	0.153	-1.829	ERLEC1	endoplasmic reticulum lectin 1	2	53867571	AF131743	27248	2p16.2	Hs.438336 Hs.713845	10	protein binding endoplasmic reticulum endoplasmic reticulum lumen
201161_s_at	-0.546	12.823	-3.395	3.931e-03	0.153	-1.830	CSDA	cold shock domain protein A	12	-10742944	NM_003651	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
208675_s_at	-0.459	8.268	-3.395	3.932e-03	0.153	-1.830	DDOST	dolichyl-diphosphooligosaccharide-protein glycosyltransferase	1	-20850846	D29643	1650	1p36.1	Hs.523145	12	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum microsome protein amino acid terminal N-glycosylation oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine response to cytokine stimulus T cell activation	N-Glycan biosynthesis Metabolic pathways
208776_at	-0.629	7.169	-3.395	3.933e-03	0.153	-1.830	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	17	27795614	BF432873	5717	17q11.2	Hs.655396	41	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
227649_s_at	0.327	5.412	3.393	3.947e-03	0.154	-1.834	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	1	204582822, 204582822	AU144000	23380	1q32.1	Hs.497575	7	GTPase activator activity intracellular signal transduction	Axon guidance
225433_at	-0.750	6.980	-3.392	3.955e-03	0.154	-1.836	GTF2A1	general transcription factor IIA, 1, 19/37kDa	14	-80716146, -80716146	AU144104	2957	14q31.1	Hs.592334 Hs.593630	45	DNA binding transcription coactivator activity nucleus nucleoplasm transcription factor TFIIA complex nucleolus cytoplasm transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter transcription factor binding general RNA polymerase II transcription factor activity TATA-binding protein binding general transcription from RNA polymerase II promoter regulation of transcription protein heterodimerization activity	Basal transcription factors
219863_at	0.510	4.663	3.391	3.966e-03	0.154	-1.838	HERC5	hect domain and RLD 5	4	89597290	NM_016323	51191	4q22.1	Hs.26663	10	regulation of cyclin-dependent protein kinase activity intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process perinuclear region of cytoplasm
212485_at	-0.716	7.334	-3.389	3.977e-03	0.155	-1.840	GPATCH8	G patch domain containing 8	17	-39828175	AU146596	23131	17q21.31	Hs.463129	8	molecular_function cellular_component biological_process
239203_at	-1.209	8.595	-3.388	3.988e-03	0.155	-1.843	C7orf53	chromosome 7 open reading frame 53	7	111908143, 111908301	AW014728	286006	7q31.1	Hs.396189	5	membrane integral to membrane
206241_at	-0.870	5.551	-3.387	3.997e-03	0.155	-1.845	KPNA5	karyopherin alpha 5 (importin alpha 6)	6	117109059	NM_002269	3841	6q22.1	Hs.182971	46	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
221559_s_at	-0.678	7.202	-3.387	4.000e-03	0.155	-1.846	MIS12	MIS12, MIND kinetochore complex component, homolog (S. pombe)	17	5330970	BC000229	79003	17p13.2	Hs.267194	11	MIS12/MIND type complex chromosome, centromeric region protein binding nucleus cell cycle chromosome segregation mitosis cell division kinetochore assembly
239839_at	0.523	4.127	3.386	4.007e-03	0.155	-1.848	ZNF555	zinc finger protein 555	19	2792481	BF435923	148254	19p13.3	Hs.47712	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221676_s_at	-0.547	5.968	-3.385	4.012e-03	0.155	-1.849	CORO1C	coronin, actin binding protein, 1C	12	-107563015	BC002342	23603	12q24.1	Hs.330384	12	actin binding phagocytosis signal transduction actin cytoskeleton
229110_at	1.060	3.472	3.385	4.012e-03	0.155	-1.849	LOC100128844	hypothetical protein LOC100128844	9		N50083	100128844	9p22.1	Hs.593150
218108_at	-0.460	6.381	-3.384	4.020e-03	0.155	-1.850	UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	14	92743153	NM_018108	55148	14q32.12	Hs.648806	7	molecular_function ubiquitin-protein ligase activity protein binding biological_process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
227424_x_at	-0.513	6.524	-3.384	4.021e-03	0.155	-1.851	C21orf119	chromosome 21 open reading frame 119	21	32687312	AI800837	84996	21q22.11	Hs.58149	2
225797_at	-0.519	7.876	-3.383	4.026e-03	0.155	-1.852	MRPL54	mitochondrial ribosomal protein L54	19	3713664	AV707568	116541	19p13.3	Hs.356578	5	mitochondrion ribosome
209139_s_at	-0.550	9.622	-3.383	4.029e-03	0.155	-1.852	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	2	-179004387, -179004387, -179004387	AF083033	8575	2q31.2	Hs.570274	27	double-stranded RNA binding protein binding intracellular cytoplasm protein amino acid phosphorylation induction of apoptosis response to stress immune response enzyme activator activity negative regulation of cell proliferation response to virus RNA interference, production of siRNA gene silencing by RNA outer ear morphogenesis middle ear morphogenesis protein homodimerization activity perinuclear region of cytoplasm skeletal system morphogenesis
1568900_a_at	0.447	3.053	3.383	4.033e-03	0.155	-1.853	ZNF568	zinc finger protein 568	19	42099073	BC031218	374900	19q13.12	Hs.404220	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221505_at	-0.478	8.351	-3.382	4.041e-03	0.156	-1.855	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	1	-148457341, -148457341	AW612574	81611	1q21.2	Hs.656466	14	protein binding nucleus cytoplasm cytoplasmic membrane-bounded vesicle phosphatase inhibitor activity
214177_s_at	-0.836	8.347	-3.381	4.048e-03	0.156	-1.857	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	1	-153183179	AI935162	57326	1q21.3	Hs.505806	8	transcription corepressor activity protein binding nucleus cytoplasm cytosol cytoskeleton microtubule multicellular organismal development negative regulation of transcription cell differentiation
208977_x_at	-0.850	8.862	-3.379	4.066e-03	0.156	-1.861	TUBB2C	tubulin, beta 2C	9	139255531	BC004188	10383	9q34	Hs.433615	25	nucleotide binding GTPase activity structural molecule activity GTP binding cytoskeleton microtubule cell motion microtubule-based movement natural killer cell mediated cytotoxicity MHC class I protein binding protein complex unfolded protein binding protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
222394_at	-0.559	7.107	-3.376	4.085e-03	0.156	-1.865	PDCD6IP	programmed cell death 6 interacting protein	3	33815069, 33815069, 33845133	BG484789	10015	3p22.3	Hs.475896	65	protein binding cytoplasm centrosome cytosol apoptosis cell cycle protein transport melanosome interspecies interaction between organisms cell division	Endocytosis
209107_x_at	-0.407	7.573	-3.376	4.089e-03	0.156	-1.866	NCOA1	nuclear receptor coactivator 1	2	24660849	U19179	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
218545_at	-0.584	7.762	-3.376	4.090e-03	0.156	-1.866	CCDC91	coiled-coil domain containing 91	12	28301399	NM_018318	55297	12p11.22	Hs.653125	8	Golgi apparatus protein transport membrane
212935_at	0.482	6.813	3.375	4.094e-03	0.156	-1.867	MCF2L	MCF.2 cell line derived transforming sequence-like	13	112670757, 112681655	AB002360	23263	13q34	Hs.170422 Hs.597691	15	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm mitochondrion plasma membrane intracellular signaling cascade regulation of Rho protein signal transduction
65517_at	0.388	6.223	3.374	4.105e-03	0.157	-1.870	AP1M2	adaptor-related protein complex 1, mu 2 subunit	19	-10544347	AA910946	10053	19p13.2	Hs.18894	28	protein binding Golgi apparatus cytosol protein targeting vesicle targeting membrane clathrin adaptor complex cytoplasmic vesicle	Lysosome
222634_s_at	-0.653	4.726	-3.373	4.111e-03	0.157	-1.871	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	3	-178221235	AF314544	79718	3q26.32	Hs.715537	14	nucleus chromatin modification modification-dependent protein catabolic process regulation of transcription	Wnt signaling pathway
226037_s_at	-0.592	6.758	-3.373	4.114e-03	0.157	-1.872	TAF9B	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	X	-77271900, 1383006	AL049589	51616	Xq13.1-q21.1	Hs.592248 Hs.643614 Hs.714006	8	DNA binding transcription corepressor activity protein binding nucleus transcription factor TFIID complex transcription initiation negative regulation of specific transcription from RNA polymerase II promoter positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptosis regulation of transcription	Basal transcription factors
221942_s_at	0.603	6.729	3.372	4.122e-03	0.157	-1.873	GUCY1A3	guanylate cyclase 1, soluble, alpha 3	4	156807311, 156807311, 156807311, 156807598, 156807598, 156808264	AI719730	2982	4q31.1-q31.2 4q31.3-q33	Hs.24258	14	nucleotide binding guanylate cyclase activity receptor activity GTP binding cytoplasm nitric oxide mediated signal transduction guanylate cyclase complex, soluble regulation of blood pressure positive regulation of cGMP biosynthetic process response to defense-related host nitric oxide production relaxation of vascular smooth muscle	Purine metabolism Vascular smooth muscle contraction Gap junction Long-term depression
244428_at	0.407	4.351	3.371	4.127e-03	0.157	-1.875	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	2	-25357824, -25309348, -25309348, -25309348	AW572279	1788	2p23	Hs.515840	54	euchromatin DNA binding DNA (cytosine-5-)-methyltransferase activity protein binding nucleus cytoplasm DNA methylation genetic imprinting methyltransferase activity zinc ion binding nuclear matrix transferase activity metal ion binding	Cysteine and methionine metabolism Metabolic pathways
203605_at	-0.524	7.496	-3.371	4.134e-03	0.157	-1.876	SRP54	signal recognition particle 54kDa	14	34521854	NM_003136	6729	14q13.2	Hs.167535	15	nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane, translocation SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition drug binding 7S RNA binding nuclear speck GDP binding endoplasmic reticulum signal peptide binding response to drug ribonucleoprotein binding	Protein export
203285_s_at	-0.635	4.425	-3.369	4.144e-03	0.157	-1.878	HS2ST1	heparan sulfate 2-O-sulfotransferase 1	1	87152922, 87152922	NM_012262	9653	1p31.1-p22.1	Hs.719144	9	Golgi apparatus membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
209032_s_at	0.701	6.063	3.369	4.144e-03	0.157	-1.878	CADM1	cell adhesion molecule 1	11	-114549554	AF132811	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
226899_at	1.034	5.673	3.369	4.149e-03	0.157	-1.879	UNC5B	unc-5 homolog B (C. elegans)	10	72642303	AK022859	219699	10q22.1	Hs.522997	12	receptor activity protein binding apoptosis signal transduction multicellular organismal development membrane integral to membrane	Axon guidance
232983_s_at	-0.435	6.112	-3.367	4.161e-03	0.158	-1.882	SERGEF	secretion regulating guanine nucleotide exchange factor	11	-17766171	AJ243951	26297	11p14.3	Hs.32470	7	guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm signal transduction negative regulation of protein secretion
1558969_a_at	0.314	5.256	3.367	4.163e-03	0.158	-1.882	RPL32P3	ribosomal protein L32 pseudogene 3	3	-130584366	BG741817	132241	3q21.3	Hs.477537 Hs.652423	2
217870_s_at	-0.563	9.052	-3.366	4.170e-03	0.158	-1.884	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	1	47572055	NM_016308	51727	1p32	Hs.714325	16	nucleotide binding cytidylate kinase activity uridine kinase activity ATP binding nucleus cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine ribonucleotide biosynthetic process transferase activity phosphotransferase activity, phosphate group as acceptor	Pyrimidine metabolism Metabolic pathways
202090_s_at	0.368	11.887	3.365	4.180e-03	0.158	-1.886	UQCR	ubiquinol-cytochrome c reductase, 6.4kDa subunit	19	-1548170	NM_006830	10975	19p13.3	Hs.8372	4	mitochondrion mitochondrial inner membrane mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity electron carrier activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
212435_at	-0.448	7.497	-3.363	4.195e-03	0.158	-1.889	TRIM33	tripartite motif-containing 33	1	-114736921	AA205593	51592	1p13.1	Hs.26837	12	DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding
214093_s_at	-0.656	6.861	-3.363	4.197e-03	0.158	-1.890	FUBP1	far upstream element (FUSE) binding protein 1	1	-78186178	AA156865	8880	1p31.1	Hs.567380	28	single-stranded DNA binding transcription factor activity RNA binding protein binding nucleus nucleolus transcription from RNA polymerase II promoter regulation of transcription
228433_at	-0.388	5.286	-3.363	4.199e-03	0.158	-1.890	NFYA	nuclear transcription factor Y, alpha	6	41148684	AU157605	4800	6p21.3	Hs.10441	55	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter CCAAT-binding factor complex	Antigen processing and presentation
226748_at	-0.932	8.208	-3.363	4.203e-03	0.158	-1.891	LYSMD2	LysM, putative peptidoglycan-binding, domain containing 2	15	-49802553, -49802553	AI674731	256586	15q21.2	Hs.631693	3	cell wall macromolecule catabolic process
224318_s_at	-0.638	8.751	-3.362	4.211e-03	0.158	-1.893	KIAA1310	KIAA1310	2	-96622633	AF311326	55683	2p12-p11.2	Hs.516341	10
208869_s_at	-0.798	6.940	-3.361	4.213e-03	0.158	-1.893	GABARAPL1	GABA(A) receptor-associated protein like 1	12	10256755	AF087847	23710	12p13.2	Hs.524250	18	protein binding intracellular cytoplasm autophagic vacuole endoplasmic reticulum Golgi apparatus microtubule membrane beta-tubulin binding GABA receptor binding	Regulation of autophagy
242408_at	-0.463	3.130	-3.361	4.217e-03	0.158	-1.894	STYX	serine/threonine/tyrosine interacting protein	14	52266632	AW968935	6815		Hs.364980	8	protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
218583_s_at	-0.480	8.112	-3.361	4.217e-03	0.158	-1.894	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	3	-184143252	NM_020640	54165	3q26.3	Hs.715661	16	molecular_function cellular_component biological_process modification-dependent protein catabolic process
208722_s_at	-0.560	7.308	-3.360	4.228e-03	0.159	-1.897	ANAPC5	anaphase promoting complex subunit 5	12	-120230432, -120230432	BC001081	51433	12q24.31	Hs.7101	28	G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
203098_at	-0.521	6.865	-3.360	4.229e-03	0.159	-1.897	CDYL	chromodomain protein, Y-like	6	4651391, 4721678, 4781330, 4835224	AL050164	9425	6p25.1	Hs.269092	8	chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription
228810_at	-0.654	5.632	-3.360	4.229e-03	0.159	-1.897	CCNYL1	cyclin Y-like 1	2	208284508	AW135279	151195	2q33.3	Hs.471234 Hs.597952	5
224711_at	-0.513	7.839	-3.358	4.242e-03	0.159	-1.900	YY1	YY1 transcription factor	14	99774854	AI670903	7528	14q	Hs.388927	97	transcription factor activity transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus transcription factor complex plasma membrane regulation of transcription from RNA polymerase II promoter zinc ion binding anterior/posterior pattern formation nuclear matrix PcG protein complex metal ion binding camera-type eye morphogenesis
218312_s_at	0.649	7.394	3.356	4.261e-03	0.159	-1.904	ZSCAN18	zinc finger and SCAN domain containing 18	19	-63310783, -63287021, -63287021	NM_023926	65982	19q13.43	Hs.235390	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203804_s_at	-0.427	8.942	-3.356	4.261e-03	0.159	-1.904	LUC7L3	LUC7-like 3 (S. cerevisiae)	17	46151975	NM_006107	51747	17q21.33	Hs.130293	15	DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck
200894_s_at	-0.592	6.051	-3.355	4.268e-03	0.159	-1.905	FKBP4	FK506 binding protein 4, 59kDa	12	2774368	AA894574	2288	12p13.33	Hs.524183 Hs.713721	47	peptidyl-prolyl cis-trans isomerase activity ATP binding GTP binding FK506 binding intracellular nucleus nucleolus cytoplasm protein folding steroid hormone receptor complex assembly copper ion transport embryo implantation isomerase activity protein binding, bridging heat shock protein binding protein complex localization glucocorticoid receptor binding male sex differentiation phosphoprotein binding
222713_s_at	-0.310	4.219	-3.355	4.272e-03	0.159	-1.906	FANCF	Fanconi anemia, complementation group F	11	-22600654	AF181995	2188	11p15	Hs.713574	27	molecular_function protein binding cellular_component nucleus DNA repair response to DNA damage stimulus biological_process
1559489_a_at	0.345	4.708	3.354	4.280e-03	0.159	-1.908	LOC257358	hypothetical LOC257358	5	169691012	AK093725	257358	5q35.1	Hs.249689	3
222742_s_at	0.455	8.412	3.354	4.281e-03	0.159	-1.908	RABL5	RAB, member RAS oncogene family-like 5	7	-100743368	AW026449	64792	7q22.1	Hs.389104	4	nucleotide binding GTP binding
212330_at	-0.575	7.561	-3.353	4.283e-03	0.159	-1.908	TFDP1	transcription factor Dp-1	13	113287003, 113287056	R60866	7027	13q34	Hs.79353	37	transcription factor activity transcription coactivator activity nucleus nucleoplasm transcription factor complex regulation of transcription from RNA polymerase II promoter cell cycle transcription factor binding cell proliferation protein domain specific binding	Cell cycle TGF-beta signaling pathway
209090_s_at	-0.658	9.676	-3.353	4.284e-03	0.159	-1.909	SH3GLB1	SH3-domain GRB2-like endophilin B1	1	86942844	AL049597	51100	1p22	Hs.136309	28	protein insertion into mitochondrial membrane during induction of apoptosis fatty acid binding protein binding nucleus cytoplasm mitochondrion mitochondrial outer membrane microsome Golgi apparatus phosphatidic acid biosynthetic process apoptosis anti-apoptosis phospholipid biosynthetic process membrane lysophosphatidic acid acyltransferase activity protein homodimerization activity protein complex 'de novo' posttranslational protein folding	Endocytosis
214493_s_at	-0.648	4.578	-3.352	4.299e-03	0.160	-1.912	INADL	InaD-like (Drosophila)	1	61980736	NM_005799	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
205019_s_at	0.459	5.899	3.349	4.318e-03	0.160	-1.916	VIPR1	vasoactive intestinal peptide receptor 1	3	42519107	NM_004624	7433	3p22	Hs.348500	65	vasoactive intestinal polypeptide receptor activity plasma membrane integral to plasma membrane muscle contraction immune response G-protein signaling, coupled to cyclic nucleotide second messenger synaptic transmission digestion positive regulation of cell proliferation	Neuroactive ligand-receptor interaction
217755_at	-1.172	7.671	-3.348	4.334e-03	0.161	-1.919	HN1	hematological and neurological expressed 1	17	-70642938, -70642938	NM_016185	51155	17q25.1	Hs.532803 Hs.713826	9	nucleus
225811_at	-0.567	9.799	-3.346	4.346e-03	0.161	-1.922	C11orf58	chromosome 11 open reading frame 58	11	16716723	AI652868	10944	11p15.1	Hs.719128	8	molecular_function cellular_component biological_process
235341_at	0.329	4.596	3.346	4.347e-03	0.161	-1.922	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	13	95127402	AL119957	5611	13q32.1	Hs.59214	19	protein kinase inhibitor activity binding cytoplasm endoplasmic reticulum response to unfolded protein response to virus heat shock protein binding
1556554_at	0.402	5.834	3.346	4.348e-03	0.161	-1.922	TRIM50	tripartite motif-containing 50	7	-72364470	AK057366	135892	7q11.23	Hs.647053	4	protein binding intracellular cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
229943_at	0.731	6.690	3.345	4.356e-03	0.161	-1.924	TRIM13	tripartite motif-containing 13	13	49469143	BF939833	10206	13q14	Hs.436922	14	signal transducer activity protein binding intracellular cytoplasm zinc ion binding anatomical structure morphogenesis positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
1565269_s_at	-0.837	5.359	-3.345	4.358e-03	0.161	-1.924	ATF1	activating transcription factor 1	12	49444085	AF047022	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
217741_s_at	-0.976	8.246	-3.345	4.358e-03	0.161	-1.924	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AW471220	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
209316_s_at	-0.600	8.606	-3.345	4.360e-03	0.161	-1.925	HBS1L	HBS1-like (S. cerevisiae)	6	-135398687, -135323215, -135323213	BC001465	10767	6q23-q24	Hs.378532	12	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation signal transduction
214334_x_at	-0.454	9.875	-3.344	4.365e-03	0.161	-1.926	DAZAP2	DAZ associated protein 2	12	49918774, 49918774	N34846	9802	12q12	Hs.369761	15	protein binding WW domain binding
215804_at	0.389	4.861	3.344	4.368e-03	0.161	-1.926	EPHA1	EPH receptor A1	7	-142798327	Z27409	2041	7q34	Hs.89839	30	nucleotide binding receptor activity ephrin receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity	Axon guidance
225878_at	-0.650	11.479	-3.343	4.381e-03	0.161	-1.929	KIF1B	kinesin family member 1B	1	10193350, 10193350	AL135264	23095	1p36.2	Hs.97858	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle
227310_at	0.342	3.014	3.342	4.388e-03	0.161	-1.931	ADSS	adenylosuccinate synthase	1	-242638418	AI346678	159	1cen-q12	Hs.498313	11	nucleotide binding magnesium ion binding immune system process adenylosuccinate synthase activity adenylosuccinate synthase activity GTP binding cellular_component cytoplasm purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process ligase activity phosphate binding	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
217817_at	-0.315	7.266	-3.341	4.394e-03	0.161	-1.932	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	3	9809226	BE891920	10093	3p25.3	Hs.323342	16	cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
208581_x_at	-0.981	10.736	-3.341	4.396e-03	0.161	-1.932	MT1X	metallothionein 1X	16	55273882	NM_005952	4501	16q13	Hs.374950	18	copper ion binding zinc ion binding response to metal ion cadmium ion binding metal ion binding
202233_s_at	0.431	11.913	3.340	4.404e-03	0.161	-1.934	UQCRH	ubiquinol-cytochrome c reductase hinge protein	1	46541966	NM_006004	7388	1p34.1	Hs.481571	9	mitochondrion mitochondrial respiratory chain oxidative phosphorylation mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity aerobic respiration membrane electron transport chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
203021_at	-1.878	5.977	-3.340	4.404e-03	0.161	-1.934	SLPI	secretory leukocyte peptidase inhibitor	20	-43314292	NM_003064	6590	20q12	Hs.517070	71	serine-type endopeptidase inhibitor activity extracellular region
223478_at	-0.470	7.772	-3.339	4.408e-03	0.161	-1.935	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)	11	-111461079	AF165967	26521	11q23.1-q23.2	Hs.279915	6	protein binding mitochondrion mitochondrial inner membrane presequence translocase complex sensory perception of sound zinc ion binding protein transport membrane mitochondrial intermembrane space protein transporter complex protein import into mitochondrial inner membrane metal ion binding intracellular protein transmembrane transport
218563_at	0.358	11.096	3.339	4.409e-03	0.161	-1.935	NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	19	59297971	NM_004542	4696	19q13.42	Hs.198269	7	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
223490_s_at	-0.472	5.070	-3.337	4.431e-03	0.162	-1.939	EXOSC3	exosome component 3	9	-37770307, -37770307	AF281132	51010	9p11	Hs.602571 Hs.713483	12	3'-5'-exoribonuclease activity nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing hydrolase activity	RNA degradation
212511_at	-0.605	6.778	-3.337	4.432e-03	0.162	-1.940	PICALM	phosphatidylinositol binding clathrin assembly protein	11	-85346132	AI766247	8301	11q14	Hs.163893	22	phospholipid binding phosphatidylinositol binding Golgi apparatus coated pit protein complex assembly receptor-mediated endocytosis membrane clathrin coat clathrin-coated vesicle clathrin binding cytoplasmic vesicle clathrin coat assembly
206174_s_at	-0.607	7.891	-3.336	4.437e-03	0.162	-1.941	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	NM_002721	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
226787_at	-0.407	5.360	-3.336	4.437e-03	0.162	-1.941	ZNF18	zinc finger protein 18	17	-11821486	BF966015	7566	17p11.2	Hs.370473	8	transcription factor activity intracellular nucleus nucleolus cytoplasm Golgi apparatus plasma membrane regulation of transcription, DNA-dependent zinc ion binding metal ion binding
243980_at	0.337	4.330	3.335	4.446e-03	0.162	-1.943	ZNF594	zinc finger protein 594	17	-5023554	AW978739	84622	17p13	Hs.658402	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203983_at	-0.475	8.627	-3.335	4.452e-03	0.162	-1.944	TSNAX	translin-associated factor X	1	229731021	NM_005999	7257	1q42.1	Hs.96247	17	nucleus cytoplasm multicellular organismal development spermatogenesis protein transporter activity cell differentiation sequence-specific DNA binding perinuclear region of cytoplasm
200597_at	-0.577	7.237	-3.334	4.455e-03	0.162	-1.945	EIF3A	eukaryotic translation initiation factor 3, subunit A	10	-120784530	AI123320	8661	10q26	Hs.523299	38	formation of translation initiation complex translation initiation factor activity translation initiation factor activity structural molecule activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex
204326_x_at	-1.004	10.673	-3.334	4.460e-03	0.162	-1.946	MT1X	metallothionein 1X	16	55273882	NM_002450	4501	16q13	Hs.374950	18	copper ion binding zinc ion binding response to metal ion cadmium ion binding metal ion binding
200767_s_at	-0.370	7.277	-3.333	4.469e-03	0.163	-1.947	FAM120A	family with sequence similarity 120A	9	95253993	NM_014612	23196	9q22.31	Hs.372003 Hs.707324	14	RNA binding cytoplasm plasma membrane
214279_s_at	-1.617	9.481	-3.332	4.476e-03	0.163	-1.949	NDRG2	NDRG family member 2	14	-20554761, -20554761	W74452	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
206587_at	-0.561	5.253	-3.331	4.485e-03	0.163	-1.951	CCT6B	chaperonin containing TCP1, subunit 6B (zeta 2)	17	-30279050	NM_006584	10693	17q12	Hs.73072	9	nucleotide binding ATP binding cytoplasm protein folding spermatogenesis protein transporter activity unfolded protein binding chaperone-mediated protein complex assembly
225108_at	-0.740	5.444	-3.331	4.486e-03	0.163	-1.951	AGPS	alkylglycerone phosphate synthase	2	177965716	BF111719	8540	2q31.2	Hs.516543	19	peroxisome peroxisomal membrane cytosol alkylglycerone-phosphate synthase activity lipid biosynthetic process membrane oxidoreductase activity transferase activity FAD binding	Ether lipid metabolism Metabolic pathways
219250_s_at	-0.892	5.099	-3.331	4.489e-03	0.163	-1.952	FLRT3	fibronectin leucine rich transmembrane protein 3	20	-14252642, -14252642	NM_013281	23767	20p11	Hs.41296	9	receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging
217884_at	-0.398	6.230	-3.330	4.493e-03	0.163	-1.952	NAT10	N-acetyltransferase 10 (GCN5-related)	11	34083686	NM_024662	55226	11p13	Hs.577281	18	nucleotide binding molecular_function protein binding ATP binding nucleus nucleolus N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
220939_s_at	-0.568	9.023	-3.330	4.494e-03	0.163	-1.952	DPP8	dipeptidyl-peptidase 8	15	-63525050, -63525050	NM_017743	54878	15q22	Hs.591106	16	aminopeptidase activity nucleus cytoplasm proteolysis immune response peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity membrane
232046_at	-0.566	6.432	-3.330	4.500e-03	0.163	-1.954	KIAA1217	KIAA1217	10	24023680, 24537725	AU148164	56243	10p12.2-p12.1	Hs.445885	5	molecular_function cytoplasm multicellular organismal development embryonic skeletal system development
208072_s_at	-0.598	8.209	-3.329	4.506e-03	0.163	-1.955	DGKD	diacylglycerol kinase, delta 130kDa	2	233927891, 233961538	NM_003648	8527	2q37.1	Hs.471675	14	nucleotide binding diacylglycerol kinase activity ATP binding cytoplasm plasma membrane epidermal growth factor receptor signaling pathway activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway multicellular organismal development zinc ion binding response to organic substance cytoplasmic membrane-bounded vesicle cell growth transferase activity second-messenger-mediated signaling diacylglycerol binding protein homodimerization activity diacylglycerol metabolic process metal ion binding protein heterodimerization activity protein homooligomerization	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phosphatidylinositol signaling system
208865_at	-0.466	9.179	-3.329	4.509e-03	0.163	-1.955	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	BG534245	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
202301_s_at	-0.708	7.267	-3.328	4.512e-03	0.163	-1.956	RSRC2	arginine/serine-rich coiled-coil 2	12	-121555225, -121555225	BE396879	65117	12q24.31	Hs.432996	4
215951_at	0.324	5.136	3.326	4.530e-03	0.163	-1.960	TBC1D2B	TBC1 domain family, member 2B	15	-76074381	AL137303	23102	15q24.3-q25.1	Hs.719242	2	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
226268_at	-0.843	6.008	-3.326	4.536e-03	0.164	-1.961	RAB21	RAB21, member RAS oncogene family	12	70434924	AI309554	23011	12q21.1	Hs.524590	12	Golgi membrane nucleotide binding protein binding GTP binding endosome endoplasmic reticulum Golgi apparatus small GTPase mediated signal transduction protein transport membrane cytoplasmic vesicle membrane cytoplasmic vesicle early endosome membrane
229412_at	-0.605	5.685	-3.325	4.540e-03	0.164	-1.962	TAF8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa	6	42126228	AA641254	129685	6p21.1	Hs.520122	17	inner cell mass cell proliferation DNA binding protein binding nucleus transcription factor TFIID complex cytoplasm multicellular organismal development transcription activator activity cell differentiation regulation of transcription regulation of fat cell differentiation positive regulation of transcription, DNA-dependent
208868_s_at	-0.555	6.745	-3.325	4.545e-03	0.164	-1.963	GABARAPL1	GABA(A) receptor-associated protein like 1	12	10256755	BF125756	23710	12p13.2	Hs.524250	18	protein binding intracellular cytoplasm autophagic vacuole endoplasmic reticulum Golgi apparatus microtubule membrane beta-tubulin binding GABA receptor binding	Regulation of autophagy
211593_s_at	-0.389	7.952	-3.322	4.570e-03	0.164	-1.968	MAST2	microtubule associated serine/threonine kinase 2	1	46041871	AB047005	23139	1p34.1	Hs.319481	19	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoskeleton plasma membrane protein amino acid phosphorylation transferase activity phosphatase binding regulation of interleukin-12 biosynthetic process spermatid differentiation
202776_at	-0.501	7.875	-3.322	4.573e-03	0.164	-1.968	DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	1	-94107923	NM_014597	30836	1p22.1	Hs.85769	10	nucleus regulation of transcription
227272_at	-0.449	7.763	-3.321	4.580e-03	0.164	-1.970	C15orf52	chromosome 15 open reading frame 52	15	-38410944	BE673226	388115	15q15.1	Hs.32433	3
207057_at	1.488	6.095	3.320	4.589e-03	0.165	-1.972	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	NM_004731	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
225268_at	-0.621	10.637	-3.320	4.592e-03	0.165	-1.972	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	AU144710	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
226117_at	0.892	5.990	3.319	4.595e-03	0.165	-1.973	TIFA	TRAF-interacting protein with forkhead-associated domain	4	-113416230	AA195074	92610	4q25	Hs.310640	9	protein binding I-kappaB kinase/NF-kappaB cascade
215884_s_at	-0.616	8.157	-3.319	4.597e-03	0.165	-1.973	UBQLN2	ubiquilin 2	X	56606796	AK001029	29978	Xp11.23-p11.1	Hs.179309	20	binding nucleus cytoplasm plasma membrane
1557545_s_at	0.617	2.649	3.318	4.612e-03	0.165	-1.976	RNF165	ring finger protein 165	18	42168184	BF529886	494470	18q21.1	Hs.501114	4	protein binding zinc ion binding metal ion binding
220094_s_at	0.496	8.746	3.318	4.612e-03	0.165	-1.976	CCDC90A	coiled-coil domain containing 90A	6	-13898998	NM_022102	63933	6p24.3-p23	Hs.214043	3	mitochondrion membrane integral to membrane
224614_at	-0.516	6.007	-3.317	4.614e-03	0.165	-1.977	DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2	16	-65312299	AK024863	1783	16q22.1	Hs.369068	10	nucleotide binding motor activity ATP binding cytoplasmic dynein complex microtubule
233558_s_at	-0.734	5.746	-3.316	4.625e-03	0.165	-1.979	C4orf41	chromosome 4 open reading frame 41	4	184817439	AK023390	60684	4q35.1	Hs.443240	6
235604_x_at	0.656	4.708	3.316	4.629e-03	0.165	-1.979	ZNF493	zinc finger protein 493	19	21371760, 21371760	AI758697	284443	19p12	Hs.656558	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203699_s_at	-0.512	3.922	-3.316	4.629e-03	0.165	-1.980	DIO2	deiodinase, iodothyronine, type II	14	-79733621, -79733621	U53506	1734	14q24.2-q24.3	Hs.202354	61	selenocysteine incorporation thyroxine 5'-deiodinase activity thyroid hormone generation selenium binding membrane integral to membrane thyroid hormone catabolic process hormone biosynthetic process oxidation reduction
212111_at	-0.438	6.915	-3.316	4.629e-03	0.165	-1.980	STX12	syntaxin 12	1	27972280	AA628051	23673	1p35-p34.1	Hs.523855	18	SNAP receptor activity Golgi apparatus intracellular protein transport membrane integral to membrane vesicle-mediated transport cholesterol efflux membrane raft phagocytic vesicle protein stabilization	SNARE interactions in vesicular transport
221599_at	0.692	9.311	3.315	4.635e-03	0.165	-1.981	C11orf67	chromosome 11 open reading frame 67	11	77209855	BC002752	28971	11q14.1	Hs.503357	3
205583_s_at	-0.524	7.057	-3.315	4.637e-03	0.165	-1.981	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_024810	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
237447_at	0.521	5.134	3.315	4.638e-03	0.165	-1.981	C22orf45	chromosome 22 open reading frame 45	22		BF509218	646023	22q11.23	Hs.712771	2
215716_s_at	-0.585	7.194	-3.315	4.640e-03	0.165	-1.982	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	12	-88505956	L14561	490	12q21.3	Hs.506276	38	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
202495_at	-0.715	7.788	-3.315	4.641e-03	0.165	-1.982	TBCC	tubulin folding cofactor C	6	-42820211	NM_003192	6903	6pter-p12.1	Hs.75064	6	binding cytoskeleton microtubule post-chaperonin tubulin folding pathway chaperone binding
204872_at	-0.893	7.931	-3.314	4.643e-03	0.165	-1.982	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	9	81376697	NM_007005	7091	9q21.31	Hs.444213	12	molecular_function nucleus biological_process Wnt receptor signaling pathway regulation of transcription
218156_s_at	-0.696	6.638	-3.314	4.643e-03	0.165	-1.982	TSR1	TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)	17	-2172731	NM_018128	55720	17p13.3	Hs.388170	5	protein binding nucleus nucleolus ribosome assembly
235306_at	0.939	5.665	3.313	4.655e-03	0.165	-1.985	GIMAP8	GTPase, IMAP family member 8	7	149778894	AI611648	155038	7q36.1	Hs.647121	7	nucleotide binding GTP binding mitochondrion endoplasmic reticulum Golgi apparatus
203811_s_at	-1.590	7.287	-3.313	4.657e-03	0.165	-1.985	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1	78243223	NM_007034	11080	1p31.1	Hs.13852	11	protein folding response to unfolded protein response to heat heat shock protein binding unfolded protein binding
211762_s_at	-1.046	6.424	-3.312	4.668e-03	0.165	-1.987	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	17	63462309, -1713110	BC005978	3838	17q24.2	Hs.594238	125	regulation of DNA recombination M phase specific microtubule process G2 phase of mitotic cell cycle protein binding nucleus nuclear pore nucleoplasm cytoplasm DNA metabolic process NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
223244_s_at	0.377	11.718	3.312	4.669e-03	0.165	-1.987	NDUFA12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	12	-93889240	AF217092	55967	12q22	Hs.506374	9	NADH dehydrogenase activity mitochondrion mitochondrial inner membrane transport response to oxidative stress respiratory gaseous exchange NADH dehydrogenase (ubiquinone) activity electron carrier activity membrane electron transport chain respiratory chain
211729_x_at	0.408	8.716	3.311	4.678e-03	0.165	-1.989	BLVRA	biliverdin reductase A	7	43764796	BC005902	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
212222_at	-0.550	8.865	-3.310	4.680e-03	0.165	-1.990	PSME4	proteasome (prosome, macropain) activator subunit 4	2	-53944707	AU143855	23198	2p16.2	Hs.413801	30	binding nucleus cytosol multicellular organismal development spermatogenesis nuclear speck cell differentiation protein complex	Proteasome
208671_at	-0.687	9.911	-3.310	4.689e-03	0.165	-1.991	SERINC1	serine incorporator 1	6	-122806191	AF164794	57515	6q22.31	Hs.146668	9	endoplasmic reticulum endoplasmic reticulum membrane plasma membrane lipid metabolic process phosphatidylserine metabolic process sphingolipid metabolic process phospholipid biosynthetic process L-serine transmembrane transporter activity L-serine transport integral to membrane positive regulation of transferase activity
1560382_at	0.306	5.326	3.310	4.689e-03	0.165	-1.991	GAB1	GRB2-associated binding protein 1	4	144477432	AK074381	2549	4q31.21	Hs.618456 Hs.80720	69	SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway	ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma
215293_s_at	0.288	6.207	3.309	4.694e-03	0.165	-1.992	PGAP2	post-GPI attachment to proteins 2	11	3775529, 3775624, 3775707, 3775765, 3785815, 3786341	AL049261	27315	11p15.5	Hs.133968	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus GPI anchor biosynthetic process protein transporter activity membrane integral to membrane
214429_at	-0.509	7.651	-3.308	4.703e-03	0.165	-1.994	MTMR6	myotubularin related protein 6	13	-24718340	U47635	9107	13q12	Hs.643702	17	protein serine/threonine phosphatase activity protein tyrosine phosphatase activity cellular_component nucleus nuclear envelope cytoplasm protein amino acid dephosphorylation calcium-activated potassium channel activity hydrolase activity phosphatase activity	Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways
209015_s_at	-0.514	10.020	-3.308	4.703e-03	0.165	-1.994	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	7	156822470, 156822471	BC002446	10049	7q36.3	Hs.593923 Hs.719116	25	ATPase activator activity DNA binding nucleus cytoplasm protein folding response to unfolded protein transcription repressor activity heat shock protein binding negative regulation of caspase activity intermediate filament organization negative regulation of transcription, DNA-dependent perinuclear region of cytoplasm chaperone binding
203238_s_at	0.467	5.554	3.307	4.710e-03	0.165	-1.995	NOTCH3	Notch homolog 3 (Drosophila)	19	-15131443	NM_000435	4854	19p13.2-p13.1	Hs.8546	96	receptor activity calcium ion binding protein binding nucleus plasma membrane Notch signaling pathway multicellular organismal development integral to membrane forebrain development regulation of transcription negative regulation of neuron differentiation neuron fate commitment regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
208835_s_at	-0.626	9.471	-3.307	4.711e-03	0.165	-1.996	LUC7L3	LUC7-like 3 (S. cerevisiae)	17	46151975	AW089673	51747	17q21.33	Hs.130293	15	DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck
221195_at	-0.556	4.261	-3.307	4.714e-03	0.165	-1.996	RNFT1	ring finger protein, transmembrane 1	17	-55384504	NM_016125	51136	17q23.1	Hs.531701	1	protein binding zinc ion binding membrane integral to membrane metal ion binding
210014_x_at	0.548	10.161	3.307	4.718e-03	0.165	-1.997	IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	20	-2587040	AF023266	3420	20p13	Hs.436405	14	magnesium ion binding isocitrate dehydrogenase (NAD+) activity mitochondrion mitochondrial matrix tricarboxylic acid cycle isocitrate metabolic process visual perception electron carrier activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding response to stimulus NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
211808_s_at	0.311	5.027	3.305	4.729e-03	0.165	-1.999	CREBBP	CREB binding protein	16	-3715056	U85962	1387	16p13.3	Hs.459759	399	histone acetyltransferase complex response to hypoxia p53 binding transcription factor activity transcription coactivator activity transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent protein complex assembly signal transduction zinc ion binding acetyltransferase activity histone acetylation transferase activity N-terminal peptidyl-lysine acetylation homeostatic process interspecies interaction between organisms positive regulation of transcription positive regulation of transcription metal ion binding MyoD binding	Cell cycle Wnt signaling pathway Notch signaling pathway TGF-beta signaling pathway Adherens junction Jak-STAT signaling pathway Long-term potentiation Melanogenesis Huntington's disease Pathways in cancer Renal cell carcinoma Prostate cancer
225677_at	-0.530	7.799	-3.305	4.730e-03	0.165	-1.999	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	AW152589	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
207543_s_at	-0.762	8.070	-3.305	4.731e-03	0.165	-1.999	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	10	-74436987	NM_000917	5033	10q21.3-q23.1	Hs.500047 Hs.593005	19	procollagen-proline 4-dioxygenase activity binding iron ion binding mitochondrion endoplasmic reticulum endoplasmic reticulum lumen oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Arginine and proline metabolism Metabolic pathways
202462_s_at	-0.483	8.113	-3.305	4.732e-03	0.165	-2.000	DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	5	134122359	NM_014829	9879	5q31.1	Hs.406549	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing Cajal body nuclear speck hydrolase activity
205331_s_at	0.349	7.232	3.305	4.733e-03	0.165	-2.000	REEP2	receptor accessory protein 2	5	137802674	NM_016606	51308	5q31	Hs.416090	10	membrane integral to membrane
224870_at	0.668	9.168	3.305	4.735e-03	0.165	-2.000	KIAA0114	KIAA0114	4	53273377	BG255416	57291	4q12	Hs.17719	4
207812_s_at	-0.579	7.617	-3.305	4.736e-03	0.165	-2.000	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	NM_015530	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
236154_at	-0.873	7.955	-3.304	4.740e-03	0.165	-2.001	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	R41907	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
1555618_s_at	-1.046	6.596	-3.304	4.745e-03	0.165	-2.002	SAE1	SUMO1 activating enzyme subunit 1	19	52325919, 52325954, 52325971	AF110956	10055	19q13.32	Hs.515500	20	ubiquitin activating enzyme activity nucleus protein modification process protein C-terminus binding protein C-terminus binding enzyme activator activity metabolic process protein ubiquitination ligase activity modification-dependent protein catabolic process ATP-dependent protein binding protein heterodimerization activity	Ubiquitin mediated proteolysis
221276_s_at	-0.775	9.068	-3.303	4.751e-03	0.165	-2.003	SYNC	syncoilin, intermediate filament protein	1	-32918093	NM_030786	81493	1p34.3-p33	Hs.712631	6	structural molecule activity protein binding cytoplasm cytosol intermediate filament Z disc sarcolemma intermediate filament-based process synapse perinuclear region of cytoplasm
231035_s_at	-1.615	5.277	-3.303	4.752e-03	0.165	-2.003	OTUD1	OTU domain containing 1	10	23768203	AI697976	220213	10p12.2	Hs.499042	4
215075_s_at	-0.570	6.789	-3.303	4.756e-03	0.165	-2.004	GRB2	growth factor receptor-bound protein 2	17	-70825751, -70825751	L29511	2885	17q24-q25	Hs.444356 Hs.708119	438	SH3/SH2 adaptor activity epidermal growth factor receptor binding Golgi apparatus cytosol cytosol epidermal growth factor receptor signaling pathway Ras protein signal transduction Ras protein signal transduction cell-cell signaling insulin receptor signaling pathway insulin receptor substrate binding interspecies interaction between organisms	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
239898_x_at	0.409	5.538	3.303	4.756e-03	0.165	-2.004	ZNF286A	zinc finger protein 286A	17	15543615	AI498484	57335	17p11.2	Hs.585799 Hs.659318	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218184_at	-0.667	6.485	-3.303	4.757e-03	0.165	-2.004	TULP4	tubby like protein 4	6	158653679	NM_020245	56995	6q25-q26	Hs.486993	7	transcription factor activity protein binding cellular_component cytoplasm regulation of transcription, DNA-dependent intracellular signaling cascade response to nutrient modification-dependent protein catabolic process
221883_at	-0.567	6.012	-3.302	4.761e-03	0.165	-2.005	PKNOX1	PBX/knotted 1 homeobox 1	21	43267711	AA133342	5316	21q22.3	Hs.431043	25	angiogenesis specific RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex cytoplasm hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity
219026_s_at	-0.535	4.301	-3.301	4.770e-03	0.165	-2.007	RASAL2	RAS protein activator like 2	1	176329486, 176577228	NM_004841	9462	1q24	Hs.549729 Hs.715627	11	Ras GTPase activator activity intracellular signal transduction regulation of small GTPase mediated signal transduction
48659_at	0.336	6.612	3.301	4.774e-03	0.165	-2.008	MIIP	migration and invasion inhibitory protein	1	12002098	W60802	60672	1p36.22	Hs.8595	4
216439_at	0.363	6.672	3.301	4.774e-03	0.165	-2.008	TNK2	tyrosine kinase, non-receptor, 2	3	-197074632, -197074632	AK024904	10188	3q29	Hs.518513	37	nucleotide binding magnesium ion binding non-membrane spanning protein tyrosine kinase activity GTPase inhibitor activity protein binding ATP binding plasma membrane protein amino acid phosphorylation small GTPase mediated signal transduction transferase activity positive regulation of peptidyl-tyrosine phosphorylation
211578_s_at	-0.497	4.928	-3.300	4.779e-03	0.165	-2.009	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	M60725	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
216048_s_at	-0.504	4.799	-3.300	4.786e-03	0.165	-2.010	RHOBTB3	Rho-related BTB domain containing 3	5	95092605	AK023621	22836	5q15	Hs.445030	13	protein binding ATP binding ATPase activity Rab GTPase binding retrograde transport, endosome to Golgi
213820_s_at	0.317	4.770	3.299	4.789e-03	0.165	-2.010	STARD5	StAR-related lipid transfer (START) domain containing 5	15	-79392061	T54159	80765	15q26	Hs.513075	12	cytosol steroid biosynthetic process lipid transport lipid binding
225395_s_at	-0.449	7.338	-3.299	4.792e-03	0.165	-2.011	FAM120AOS	family with sequence similarity 120A opposite strand	9	-95248602	AI309997	158293	9q22.31	Hs.350364 Hs.709859	3
212254_s_at	-0.414	10.289	-3.298	4.801e-03	0.165	-2.013	DST	dystonin	6	-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743	AI798790	667	6p12.1	Hs.631992 Hs.669931	48	actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding
1556988_s_at	-0.410	6.916	-3.298	4.802e-03	0.165	-2.013	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	BE220618	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
1570035_at	0.514	3.708	3.297	4.808e-03	0.166	-2.014	TBC1D10A	TBC1 domain family, member 10A	22	-29017978	BC007908	83874	22q12.1-qter	Hs.655273	13	Rab GTPase activator activity protein binding intracellular microvillus biological_process PDZ domain binding regulation of Rab GTPase activity
219806_s_at	-0.649	5.718	-3.297	4.812e-03	0.166	-2.015	C11orf75	chromosome 11 open reading frame 75	11	-92851286	NM_020179	56935	11q13.3-q23.3	Hs.438064	3	molecular_function cellular_component biological_process membrane integral to membrane
234851_at	0.333	4.052	3.297	4.816e-03	0.166	-2.016	IGL@	immunoglobulin lambda locus	22		AJ275399	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
221502_at	-0.778	10.595	-3.297	4.817e-03	0.166	-2.016	KPNA3	karyopherin alpha 3 (importin alpha 4)	13	-49171444	AL120704	3839	13q14.3	Hs.527919	61	protein binding nucleus nuclear pore cytoplasm protein complex assembly NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity
223904_at	-1.106	6.778	-3.296	4.819e-03	0.166	-2.016	PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	2	-219395349	AF214519	53632	2q35	Hs.591634	13	AMP-activated protein kinase activity glycogen biosynthetic process fatty acid biosynthetic process protein kinase cascade glucose transport protein kinase binding	Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
219963_at	-0.519	10.097	-3.296	4.822e-03	0.166	-2.017	DUSP13	dual specificity phosphatase 13	10	-76524197, -76524195	NM_016364	51207	10q22.2	Hs.178170	9	protein tyrosine phosphatase activity protein amino acid dephosphorylation meiosis spermatogenesis protein tyrosine/serine/threonine phosphatase activity hydrolase activity
208857_s_at	-0.466	10.307	-3.294	4.839e-03	0.166	-2.020	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	6	150112523	M93008	5110	6q24-q25	Hs.279257	25	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding
1555326_a_at	-0.768	4.830	-3.294	4.843e-03	0.166	-2.021	ADAM9	ADAM metallopeptidase domain 9 (meltrin gamma)	8	38973661, 38973661	AF495383	8754	8p11.22	Hs.591852	36	activation of MAPKK activity metalloendopeptidase activity protein kinase C binding integrin binding integrin binding integrin binding collagen binding extracellular region extracellular space cytoplasm plasma membrane proteolysis response to oxidative stress cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway peptidase activity zinc ion binding cell surface response to manganese ion integral to membrane SH3 domain binding SH3 domain binding keratinocyte differentiation intrinsic to external side of plasma membrane positive regulation of cell adhesion mediated by integrin cell-cell adhesion mediated by integrin positive regulation of macrophage fusion response to tumor necrosis factor monocyte activation response to hydrogen peroxide laminin binding metal ion binding positive regulation of protein secretion positive regulation of membrane protein ectodomain proteolysis PMA-inducible membrane protein ectodomain proteolysis response to glucocorticoid stimulus positive regulation of keratinocyte migration response to calcium ion
208777_s_at	-0.420	8.974	-3.294	4.843e-03	0.166	-2.021	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	17	27795614	AF001212	5717	17q11.2	Hs.655396	41	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
204772_s_at	-0.611	5.919	-3.294	4.843e-03	0.166	-2.021	TTF1	transcription termination factor, RNA polymerase I	9	-134240757	NM_007344	7270	9q34.13	Hs.54780	18	DNA binding transcription termination factor activity nucleus nucleoplasm nucleolus transcription termination negative regulation of DNA replication regulation of transcription
224851_at	0.583	4.495	3.293	4.856e-03	0.166	-2.023	CDK6	cyclin-dependent kinase 6	7	-92072172, -92072172	AW274756	1021	7q21-q22	Hs.119882	95	G1 phase of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex ruffle positive regulation of cell-matrix adhesion cyclin-dependent protein kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation regulation of gene expression regulation of gene expression transferase activity hemopoiesis cyclin binding gliogenesis cell dedifferentiation regulation of erythrocyte differentiation negative regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of fibroblast proliferation negative regulation of epithelial cell proliferation cell division	Cell cycle p53 signaling pathway Pathways in cancer Pancreatic cancer Glioma Melanoma Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer
225342_at	0.927	5.487	3.292	4.858e-03	0.166	-2.024	AK3L1	adenylate kinase 3-like 1	1	65385819, 65386100, 65386473	AK026966	205	1p31.3	Hs.10862 Hs.592601	10	nucleotide binding adenylate kinase activity ATP binding GTP binding mitochondrion mitochondrial matrix nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity	Purine metabolism Metabolic pathways
222479_s_at	-0.469	8.021	-3.292	4.864e-03	0.166	-2.025	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	3	-32542470	AK001081	51143	3p22.3	Hs.529495	11	nucleotide binding motor activity ATP binding microtubule dynein complex
1562299_at	0.303	3.018	3.290	4.879e-03	0.166	-2.028	C14orf25	chromosome 14 open reading frame 25	14		BC038110	319089	14q21.1	Hs.659936	2
202501_at	-0.761	7.499	-3.290	4.882e-03	0.166	-2.028	MAPRE2	microtubule-associated protein, RP/EB family, member 2	18	30810889, 30812205, 30875321	NM_014268	10982	18q12.1-q12.2	Hs.532824	27	cytoplasm microtubule cell cycle mitosis signal transduction microtubule binding cell proliferation cell division
222658_s_at	-0.348	6.310	-3.290	4.883e-03	0.166	-2.028	APTX	aprataxin	9	-32962607, -32962607, -32962607, -32962607, -32962607	BC001628	54840	9p13.3	Hs.20158	41	single strand break repair chromatin chromatin binding damaged DNA binding double-stranded DNA binding double-stranded RNA binding intracellular nucleus nucleoplasm nucleolus response to DNA damage stimulus cell death zinc ion binding phosphoglycolate phosphatase activity hydrolase activity regulation of protein stability DNA 5'-adenosine monophosphate hydrolase activity response to hydrogen peroxide metal ion binding protein N-terminus binding
234257_at	0.473	4.401	3.290	4.886e-03	0.166	-2.029	TNS3	tensin 3	7	-47281276	AL137468	64759	7p12.3	Hs.520814	12	protein binding nucleus nucleolus cytoplasm plasma membrane focal adhesion positive regulation of cell proliferation cell migration cell junction lung alveolus development
223982_s_at	-0.417	8.445	-3.289	4.890e-03	0.166	-2.030	PNPLA8	patatin-like phospholipase domain containing 8	7	-107899306	AB041261	50640	7q31	Hs.617340	13	lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm
204783_at	-1.739	7.532	-3.289	4.891e-03	0.166	-2.030	MLF1	myeloid leukemia factor 1	3	159771646	AI911434	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
229328_at	0.483	4.274	3.287	4.910e-03	0.167	-2.033	ZNF540	zinc finger protein 540	19	42734147	T90358	163255	19q13.12	Hs.121283	5	DNA binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
215015_at	0.319	5.551	3.287	4.914e-03	0.167	-2.034	CCDC64	coiled-coil domain containing 64	12	118912030	AA319460	92558	12q24.23	Hs.369763
224597_at	-0.460	10.927	-3.286	4.918e-03	0.167	-2.035	LOC647979	hypothetical LOC647979	20	-34096955	AV729406	647979	20q11.23	Hs.649310 Hs.718413	2
203689_s_at	-0.593	6.098	-3.286	4.919e-03	0.167	-2.035	FMR1	fragile X mental retardation 1	X	146801200	AI743037	2332	Xq27.3	Hs.103183	211	mRNA binding protein binding soluble fraction nucleus nucleoplasm nucleolus cytoplasm transport polysomal ribosome mRNA transport
218649_x_at	-0.809	8.146	-3.286	4.922e-03	0.167	-2.036	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	NM_004713	9147	14q22	Hs.655964	8	nucleus cytoplasm
210094_s_at	-0.460	7.207	-3.285	4.929e-03	0.167	-2.037	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AF196186	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
1558168_at	0.300	4.033	3.285	4.934e-03	0.167	-2.038	C3orf47	chromosome 3 open reading frame 47	3	130517803	AL040547	339942	3q21.3	Hs.450096 Hs.75307	5
208652_at	-0.512	9.460	-3.284	4.938e-03	0.167	-2.039	PPP2CA	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	5	-133560046	BC000400	5515	5q31.1	Hs.105818	105	protein phosphatase type 2A complex inactivation of MAPK activity chromosome, centromeric region phosphoprotein phosphatase activity iron ion binding protein binding soluble fraction nucleus cytoplasm mitochondrion spindle cytosol plasma membrane regulation of DNA replication protein amino acid dephosphorylation ceramide metabolic process induction of apoptosis mesoderm development RNA splicing response to organic substance hydrolase activity second-messenger-mediated signaling regulation of Wnt receptor signaling pathway manganese ion binding regulation of cell adhesion negative regulation of cell growth regulation of growth negative regulation of tyrosine phosphorylation of Stat3 protein regulation of transcription regulation of cell differentiation metal ion binding protein heterodimerization activity	Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression
203487_s_at	-0.584	8.120	-3.284	4.938e-03	0.167	-2.039	ARMC8	armadillo repeat containing 8	3	139388837, 139388837	NM_015396	25852	3q22.3	Hs.719108	4	binding
225550_at	-0.958	7.294	-3.284	4.942e-03	0.167	-2.039	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	AV700816	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
217938_s_at	-0.517	9.082	-3.284	4.943e-03	0.167	-2.040	KCMF1	potassium channel modulatory factor 1	2	85051741	NM_020122	56888	2p11.2	Hs.654968	7	intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
201032_at	-0.594	9.957	-3.283	4.957e-03	0.167	-2.042	BLCAP	bladder cancer associated protein	20	-35579232	NM_006698	10904	20q11.2-q12	Hs.472651 Hs.718404	9	membrane integral to membrane
224974_at	-0.652	5.141	-3.282	4.962e-03	0.167	-2.043	SUDS3	suppressor of defective silencing 3 homolog (S. cerevisiae)	12	117298740	AK024460	64426	12q24.23	Hs.416630 Hs.602312	9	protein binding negative regulation of transcription chromatin modification Sin3 complex histone deacetylase binding
205116_at	-0.536	6.684	-3.282	4.964e-03	0.167	-2.043	LAMA2	laminin, alpha 2	6	129245978	NM_000426	3908	6q22-q23	Hs.200841	40	receptor binding structural molecule activity extracellular region basal lamina laminin-1 complex muscle organ development regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission, cholinergic sarcolemma regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
222576_s_at	0.312	5.392	3.282	4.966e-03	0.167	-2.044	EIF2C1	eukaryotic translation initiation factor 2C, 1	1	36121396	AW071829	26523	1p35-p34	Hs.22867	26	cytoplasmic mRNA processing body nuclear-transcribed mRNA catabolic process RNA binding protein binding cytoplasm regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation regulation of transcription
223140_s_at	-0.459	7.950	-3.281	4.973e-03	0.167	-2.045	DHX36	DEAH (Asp-Glu-Ala-His) box polypeptide 36	3	-155476150	AF217190	170506	3p13-q23	Hs.446270	13	nucleotide binding nucleic acid binding helicase activity protein binding ATP binding nucleus cytoplasm ATP-dependent helicase activity hydrolase activity
204342_at	-0.647	6.424	-3.279	4.993e-03	0.167	-2.049	SLC25A24	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24	1	-108478969, -108478969	NM_013386	29957	1p13.3	Hs.656870	4	binding calcium ion binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
235082_at	-0.624	4.866	-3.279	4.994e-03	0.167	-2.049	PCNX	pecanex homolog (Drosophila)	14	70443874	BG024649	22990	14q24.2	Hs.446559	10	membrane integral to membrane
208803_s_at	-0.685	5.248	-3.278	5.000e-03	0.167	-2.050	SRP72	signal recognition particle 72kDa	4	57028518	AF069765	6731	4q11	Hs.237825	18	signal recognition particle binding binding cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane 7S RNA binding response to drug	Protein export
218530_at	-0.644	8.336	-3.277	5.013e-03	0.167	-2.052	FHOD1	formin homology 2 domain containing 1	16	-65820792	NM_013241	29109	16q22	Hs.95231	25	actin binding protein binding nucleus cytoplasm cytoskeleton cellular component organization actin cytoskeleton organization
201155_s_at	0.418	9.746	3.277	5.017e-03	0.167	-2.053	MFN2	mitofusin 2	1	11962824	NM_014874	9927	1p36.22	Hs.376681	43	nucleotide binding blastocyst formation GTPase activity protein binding GTP binding mitochondrion cytosol protein targeting to mitochondrion mitochondrial membrane organization cell cycle arrest mitochondrial fusion microtubule cytoskeleton membrane integral to membrane hydrolase activity intrinsic to mitochondrial outer membrane negative regulation of Ras protein signal transduction camera-type eye morphogenesis negative regulation of smooth muscle cell proliferation mitochondrion localization
229689_s_at	-0.733	3.574	-3.277	5.018e-03	0.167	-2.053	DLG5	discs, large homolog 5 (Drosophila)	10	-79220554	AV721789	9231	10q23	Hs.652690	49	protein binding intracellular cytoplasm plasma membrane cell-cell adherens junction intracellular signaling cascade negative regulation of cell proliferation cell-cell adhesion cell junction receptor signaling complex scaffold activity regulation of apoptosis
222125_s_at	0.390	6.465	3.276	5.020e-03	0.167	-2.054	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	3	49002344	BC000580	54681	3p21.31	Hs.654944	9	iron ion binding calcium ion binding endoplasmic reticulum membrane integral to membrane oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding oxidation reduction
202374_s_at	-0.350	6.766	-3.276	5.021e-03	0.167	-2.054	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	NM_012414	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
243864_at	-0.408	4.085	-3.276	5.027e-03	0.167	-2.055	CCDC80	coiled-coil domain containing 80	3	-113806098	AA994712	151887	3q13.2	Hs.477128	10	fibronectin binding extracellular region basement membrane interstitial matrix heparin binding positive regulation of cell-substrate adhesion extracellular matrix organization intracellular membrane-bounded organelle
201831_s_at	-0.965	8.187	-3.276	5.027e-03	0.167	-2.055	USO1	USO1 homolog, vesicle docking protein (yeast)	4	76868852	BE875592	8615	4q21.1	Hs.292689	34	Golgi membrane protein binding cytoplasm microsome Golgi apparatus cytosol intracellular protein transport protein transporter activity membrane vesicle-mediated transport vesicle fusion with Golgi apparatus perinuclear region of cytoplasm
217364_x_at	-0.637	5.559	-3.276	5.027e-03	0.167	-2.055	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	AL031313	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
224871_at	-0.472	7.753	-3.275	5.039e-03	0.168	-2.057	TPRG1L	tumor protein p63 regulated 1-like	1	3531415	AK025464	127262	1p36.32	Hs.20529	5	synaptic vesicle cell junction cytoplasmic vesicle synapse
223334_at	0.598	10.036	3.274	5.043e-03	0.168	-2.058	TMEM126A	transmembrane protein 126A	11	85036692	AL136941	84233	11q14.1	Hs.533725	8	molecular_function mitochondrion biological_process membrane integral to membrane
241389_at	0.282	6.607	3.274	5.044e-03	0.168	-2.058	CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	1	152806880	BE261002	1141	1q21.3	Hs.2306	59	conditioned taste aversion response to hypoxia nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport calcium ion transport smooth muscle contraction signal transduction synaptic transmission, cholinergic visual perception sensory perception of sound memory locomotory behavior visual learning external side of plasma membrane acetylcholine receptor activity integral to membrane sensory perception of pain vestibulocochlear nerve development optic nerve morphogenesis lateral geniculate nucleus development central nervous system projection neuron axonogenesis cell junction positive regulation of B cell proliferation positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion behavioral response to nicotine social behavior regulation of dopamine metabolic process B cell activation response to cocaine regulation of circadian sleep/wake cycle, REM sleep regulation of circadian sleep/wake cycle, non-REM sleep synapse postsynaptic membrane response to ethanol negative regulation of action potential regulation of dendrite morphogenesis cognition membrane depolarization regulation of synaptogenesis synaptic transmission involved in micturition
241458_at	-0.371	4.612	-3.273	5.060e-03	0.168	-2.061	SETD2	SET domain containing 2	3	-47032903	AI868267	29072	3p21.31	Hs.517941	18	DNA binding protein binding nucleus methyltransferase activity oxidoreductase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription transition metal ion binding	Lysine degradation
222510_s_at	-0.541	6.259	-3.272	5.063e-03	0.168	-2.061	MKRN2	makorin ring finger protein 2	3	12573593	AI809203	23609	3p25	Hs.591666	5	molecular_function nucleic acid binding protein binding intracellular biological_process zinc ion binding metal ion binding
222800_at	0.288	5.112	3.271	5.075e-03	0.168	-2.064	TRNAU1AP	tRNA selenocysteine 1 associated protein 1	1	28752115	BC000680	54952	1p35.3	Hs.533626	5	nucleotide binding selenocysteine incorporation RNA binding nucleus cytoplasm translation
222408_s_at	-0.522	8.246	-3.270	5.086e-03	0.168	-2.066	YPEL5	yippee-like 5 (Drosophila)	2	30223253	BC000836	51646	2p23.1	Hs.515890	6
228342_s_at	-1.046	8.465	-3.270	5.092e-03	0.168	-2.067	ALPK3	alpha-kinase 3	15	83160914	AA843297	57538	15q25.2	Hs.459183	5	protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation multicellular organismal development heart development kinase activity transferase activity
242586_at	-0.800	6.623	-3.269	5.094e-03	0.168	-2.067	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	H07986	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
207614_s_at	-0.555	7.395	-3.269	5.099e-03	0.168	-2.068	CUL1	cullin 1	7	148026865	NM_003592	8454	7q36.1	Hs.146806	72	G1/S transition of mitotic cell cycle protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process apoptosis cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals organ morphogenesis SCF ubiquitin ligase complex ubiquitin protein ligase binding positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
204681_s_at	0.730	5.967	3.267	5.119e-03	0.169	-2.072	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	7	-22124432	NM_012294	9771	7p15.3	Hs.174768 Hs.713217	10	intracellular nucleus nervous system development Rap guanyl-nucleotide exchange factor activity GTP-dependent protein binding regulation of small GTPase mediated signal transduction
202984_s_at	-0.504	6.697	-3.267	5.122e-03	0.169	-2.072	BAG5	BCL2-associated athanogene 5	14	-103092641, -103092641, -103092641	AA457021	9529	14q32.33	Hs.5443	10	protein binding protein folding apoptosis
210284_s_at	-0.599	6.650	-3.267	5.124e-03	0.169	-2.072	MAP3K7IP2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	6	149680755	AF241230	23118	6q25.1-q25.3	Hs.269775	39	protein binding intracellular cytoplasm cytosol cytosol zinc ion binding membrane positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway Toll-like receptor signaling pathway
222542_x_at	-1.025	6.701	-3.265	5.138e-03	0.169	-2.075	CABC1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	1	225194560	BF724826	56997	1q42.13	Hs.118241	10	nucleotide binding ATP binding mitochondrion cell death kinase activity transferase activity
206562_s_at	-0.781	6.685	-3.265	5.141e-03	0.169	-2.075	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	NM_001892	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
201736_s_at	-0.419	6.603	-3.264	5.148e-03	0.169	-2.077	MARCH6	membrane-associated ring finger (C3HC4) 6	5	10406827	BF000409	10299	5p15.2	Hs.432862	8	endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
233750_s_at	-0.761	5.204	-3.264	5.155e-03	0.169	-2.078	C1orf25	chromosome 1 open reading frame 25	1	-183353840	AL109865	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
201637_s_at	-0.452	10.494	-3.262	5.169e-03	0.170	-2.080	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	NM_005087	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
205150_s_at	-0.685	5.425	-3.262	5.174e-03	0.170	-2.081	KIAA0644	KIAA0644 gene product	7	-28959498	AV724192	9865	7p14.3	Hs.719240	4	protein binding membrane integral to membrane
1559520_at	0.352	2.784	3.261	5.180e-03	0.170	-2.082	GYPA	glycophorin A (MNS blood group)	4	-145249905	AL833104	2993	4q28.2-q31.1	Hs.434973	60	membrane fraction plasma membrane integral to membrane identical protein binding	Hematopoietic cell lineage
213330_s_at	-0.610	7.969	-3.261	5.181e-03	0.170	-2.082	STIP1	stress-induced-phosphoprotein 1	11	63710162	BE886580	10963	11q13	Hs.337295	34	protein binding nucleus cytoplasm Golgi apparatus response to stress	Prion diseases
224839_s_at	0.959	7.443	3.261	5.184e-03	0.170	-2.083	GPT2	glutamic pyruvate transaminase (alanine aminotransferase) 2	16	45475808, 45476602	BG328998	84706	16q12.1	Hs.460693	9	L-alanine:2-oxoglutarate aminotransferase activity transaminase activity biosynthetic process pyridoxal phosphate binding	Alanine, aspartate and glutamate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
226310_at	-0.693	5.876	-3.260	5.189e-03	0.170	-2.084	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	AI743511	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
217784_at	-0.443	6.689	-3.260	5.198e-03	0.170	-2.085	YKT6	YKT6 v-SNARE homolog (S. cerevisiae)	7	44207102	BE384482	10652	7p15.1	Hs.520794	19	SNAP receptor activity cytoplasm endosome endoplasmic reticulum Golgi apparatus cytosol integral to plasma membrane ER to Golgi vesicle-mediated transport vesicle targeting vesicle docking during exocytosis protein transport membrane transferase activity protein-cysteine S-palmitoleyltransferase activity SNARE complex SNARE complex cytoplasmic vesicle retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
205011_at	0.461	6.303	3.258	5.216e-03	0.170	-2.089	VWA5A	von Willebrand factor A domain containing 5A	11	123491320, 123491320	NM_014622	4013	11q23	Hs.152944	5
210538_s_at	0.576	3.460	3.257	5.226e-03	0.170	-2.090	BIRC3	baculoviral IAP repeat-containing 3	11	101693403	U37546	330	11q22	Hs.127799	92	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm anti-apoptosis cell surface receptor linked signal transduction zinc ion binding regulation of apoptosis metal ion binding	Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer
211212_s_at	-0.712	4.231	-3.256	5.240e-03	0.171	-2.093	ORC5L	origin recognition complex, subunit 5-like (yeast)	7	-103595859, -103554023	AF081459	5001	7q22.1	Hs.432948	28	nucleotide binding DNA replication origin binding ATP binding nucleus nucleoplasm DNA replication DNA replication DNA replication initiation identical protein binding	Cell cycle
201588_at	-0.314	10.440	-3.255	5.242e-03	0.171	-2.093	TXNL1	thioredoxin-like 1	18	-52421050	NM_004786	9352	18q21.31	Hs.114412	15	cytoplasm transport disulfide oxidoreductase activity electron transport chain cell redox homeostasis
226538_at	-0.658	7.174	-3.255	5.244e-03	0.171	-2.094	MAN2A1	mannosidase, alpha, class 2A, member 1	5	109053054	AV700323	4124	5q21-q22	Hs.432822	29	Golgi membrane in utero embryonic development liver development alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing mitochondrion organization vacuole organization respiratory gaseous exchange metabolic process zinc ion binding membrane integral to membrane hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding lung alveolus development	N-Glycan biosynthesis Metabolic pathways
201904_s_at	0.838	6.793	3.255	5.250e-03	0.171	-2.094	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF031714	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
238697_at	0.452	3.047	3.254	5.258e-03	0.171	-2.096	NCRNA00086	non-protein coding RNA 86	X	134383533	AA565509	399668	Xq26.3	Hs.374414	3
219448_at	-1.822	7.532	-3.253	5.273e-03	0.171	-2.099	TMEM70	transmembrane protein 70	8	75050983	BC002748	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
206408_at	0.394	3.452	3.252	5.277e-03	0.171	-2.099	LRRTM2	leucine rich repeat transmembrane neuronal 2	5	-138232977	NM_015564	26045	5q31.2	Hs.656653	6	protein binding membrane integral to membrane
218630_at	0.285	5.884	3.252	5.284e-03	0.171	-2.100	MKS1	Meckel syndrome, type 1	17	-53637796	NM_017777	54903	17q22	Hs.408843	13
221215_s_at	0.357	5.756	3.251	5.292e-03	0.172	-2.102	RIPK4	receptor-interacting serine-threonine kinase 4	21	-42032597	NM_020639	54101	21q22.3	Hs.517310	13	nucleotide binding protein serine/threonine kinase activity receptor activity ATP binding cytoplasm protein amino acid phosphorylation membrane transferase activity
202641_at	0.457	6.960	3.250	5.298e-03	0.172	-2.103	ARL3	ADP-ribosylation factor-like 3	10	-104423477	NM_004311	403	10q23.3	Hs.182215	18	nucleotide binding magnesium ion binding GTP binding intracellular nucleus Golgi apparatus spindle cell cycle small GTPase mediated signal transduction membrane cell division
203773_x_at	0.409	8.645	3.250	5.305e-03	0.172	-2.104	BLVRA	biliverdin reductase A	7	43764796	NM_000712	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
201366_at	-0.554	9.200	-3.249	5.307e-03	0.172	-2.104	ANXA7	annexin A7	10	-74805194	NM_004034	310	10q21.1-q21.2	Hs.631827	24	calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding
213589_s_at	0.497	5.805	3.249	5.309e-03	0.172	-2.105	B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1	17	-78494955	AW468201	146712	17q25.3	Hs.718480	5	transferase activity, transferring glycosyl groups
202012_s_at	-0.505	6.047	-3.249	5.316e-03	0.172	-2.106	EXT2	exostoses (multiple) 2	11	44073674	AA196245	2132	11p12-p11	Hs.368404	55	ossification mesoderm formation protein binding endoplasmic reticulum Golgi apparatus glycosaminoglycan biosynthetic process signal transduction heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process membrane integral to membrane cell differentiation intrinsic to endoplasmic reticulum membrane heparan sulfate N-acetylglucosaminyltransferase activity protein homodimerization activity protein heterodimerization activity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	Heparan sulfate biosynthesis Metabolic pathways
222422_s_at	-0.467	7.071	-3.249	5.317e-03	0.172	-2.106	NDFIP1	Nedd4 family interacting protein 1	5	141468507	AW167859	80762	5q31.3	Hs.653510 Hs.9788	11	signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport
217850_at	-0.636	7.880	-3.248	5.320e-03	0.172	-2.107	GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	3	52694975	NM_014366	26354	3p21.1	Hs.313544	29	nucleotide binding protein binding GTP binding intracellular nucleus nucleoplasm nucleolus regulation of cell proliferation
225288_at	0.702	5.649	3.248	5.325e-03	0.172	-2.107	COL27A1	collagen, type XXVII, alpha 1	9	115958051	AI949136	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
204042_at	-0.706	6.999	-3.247	5.330e-03	0.172	-2.108	WASF3	WAS protein family, member 3	13	26029839	AB020707	10810	13q12	Hs.635221	19	actin binding cytoplasm cytoskeleton protein complex assembly actin filament polymerization	Adherens junction Fc gamma R-mediated phagocytosis
211686_s_at	-0.528	6.971	-3.247	5.332e-03	0.172	-2.109	MAK16	MAK16 homolog (S. cerevisiae)	8	33462226	AF251062	84549	8p12	Hs.583805	10	nucleus nucleolus
201393_s_at	-0.674	8.969	-3.247	5.340e-03	0.172	-2.110	IGF2R	insulin-like growth factor 2 receptor	6	160310120	NM_000876	3482	6q26	Hs.487062	101	glycoprotein binding receptor activity insulin-like growth factor receptor activity transporter activity insulin-like growth factor binding mannose binding membrane fraction nucleus nuclear envelope lumen cytoplasm lysosome endosome Golgi apparatus integral to plasma membrane transport receptor-mediated endocytosis signal transduction membrane trans-Golgi network transport vesicle	Lysosome
215992_s_at	-0.421	4.153	-3.246	5.347e-03	0.172	-2.111	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	4	160408447	AL117397	9693	4q32.1	Hs.113912	14	MAPKKK cascade signal transducer activity guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular plasma membrane integral to plasma membrane Rap guanyl-nucleotide exchange factor activity cAMP-mediated signaling diacylglycerol binding Rap GTPase activator activity regulation of small GTPase mediated signal transduction	MAPK signaling pathway
223200_s_at	-0.748	6.350	-3.245	5.353e-03	0.172	-2.112	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	3	-195842806	AI219740	55341	3q29	Hs.518505	12	nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export
203266_s_at	-0.495	6.793	-3.244	5.364e-03	0.172	-2.114	MAP2K4	mitogen-activated protein kinase kinase 4	17	11864859	NM_003010	6416	17p11.2	Hs.514681	92	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding protein amino acid phosphorylation signal transduction JNK cascade transferase activity	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection
228113_at	0.334	3.387	3.243	5.381e-03	0.172	-2.117	RAB37	RAB37, member RAS oncogene family	17	70178850, 70244553, 70244950	R62453	326624	17q25.1	Hs.592097	11	nucleotide binding GTP binding ER-Golgi intermediate compartment small GTPase mediated signal transduction protein transport cytoplasmic vesicle
202716_at	-0.394	6.465	-3.242	5.387e-03	0.172	-2.118	PTPN1	protein tyrosine phosphatase, non-receptor type 1	20	48560297	NM_002827	5770	20q13.1-q13.2	Hs.417549	144	protein tyrosine phosphatase activity protein binding endoplasmic reticulum protein amino acid dephosphorylation signal transduction zinc ion binding membrane hydrolase activity negative regulation of insulin receptor signaling pathway	Adherens junction Insulin signaling pathway
201599_at	-0.924	9.166	-3.242	5.390e-03	0.172	-2.119	OAT	ornithine aminotransferase (gyrate atrophy)	10	-126075861	NM_000274	4942	10q26	Hs.523332	28	ornithine-oxo-acid transaminase activity protein binding cytoplasm mitochondrion mitochondrial matrix visual perception transferase activity pyridoxal phosphate binding	Arginine and proline metabolism Metabolic pathways
226453_at	-0.467	7.199	-3.242	5.390e-03	0.172	-2.119	RNASEH2C	ribonuclease H2, subunit C	11	-65241719	BF982002	84153	11q13.1	Hs.718438	9	nucleus	DNA replication
221150_at	0.366	4.975	3.241	5.405e-03	0.173	-2.121	MEPE	matrix extracellular phosphoglycoprotein	4	88973163	NM_020203	56955	4q21.1	Hs.676357	13	skeletal system development extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix negative regulation of bone mineralization
206614_at	0.344	5.363	3.240	5.410e-03	0.173	-2.122	GDF5	growth differentiation factor 5	20	-33484562	NM_000557	8200	20q11.2	Hs.1573	58	cytokine activity protein binding extracellular region extracellular space transforming growth factor beta receptor signaling pathway cell-cell signaling growth factor activity embryonic limb morphogenesis positive regulation of chondrocyte differentiation post-embryonic hindlimb morphogenesis forelimb morphogenesis growth regulation of multicellular organism growth regulation of apoptosis	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
200764_s_at	-0.417	6.736	-3.240	5.413e-03	0.173	-2.123	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	5	138117005	AI826881	1495	5q31	Hs.534797 Hs.656653	70	structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding	Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC)
213435_at	-0.532	5.922	-3.240	5.416e-03	0.173	-2.123	SATB2	SATB homeobox 2	2	-199842468	AB028957	23314	2q33	Hs.516617	9	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
202845_s_at	-0.454	7.788	-3.239	5.418e-03	0.173	-2.123	RALBP1	ralA binding protein 1	18	9465529	NM_006788	10928	18p11.3	Hs.528993 Hs.719181	42	GTPase activator activity protein binding intracellular transport chemotaxis signal transduction small GTPase mediated signal transduction membrane ATPase activity Ral GTPase binding Rac GTPase activator activity regulation of GTPase activity positive regulation of Cdc42 GTPase activity ATPase activity, coupled to movement of substances Rac GTPase binding	Pathways in cancer Pancreatic cancer
1553267_a_at	0.296	2.281	3.239	5.421e-03	0.173	-2.124	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	4	-78853564	NM_144571	246175	4q13.3	Hs.592519	5	exonuclease activity protein binding cytoplasm mRNA processing hydrolase activity	RNA degradation
233814_at	0.409	4.042	3.239	5.424e-03	0.173	-2.124	EFNA5	ephrin-A5	5	-106740488	AK025909	1946	5q21	Hs.288741	27	protein binding extracellular space plasma membrane cell-cell signaling multicellular organismal development nervous system development cell differentiation anchored to plasma membrane ephrin receptor binding	Axon guidance
220606_s_at	-0.740	6.229	-3.238	5.435e-03	0.173	-2.126	C17orf48	chromosome 17 open reading frame 48	17	10541651	NM_020233	56985	17p13.1	Hs.47668 Hs.708369	2	zinc ion binding hydrolase activity metal ion binding ADP-ribose diphosphatase activity CDP-glycerol diphosphatase activity
218750_at	-0.609	5.525	-3.237	5.440e-03	0.173	-2.127	TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	11	-93108745	NM_024116	79101	11q21	Hs.355750	6	DNA binding protein binding nucleus regulation of transcription
203396_at	-0.355	9.065	-3.237	5.449e-03	0.173	-2.129	PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	15	76619801	NM_002789	5685	15q25.1	Hs.251531	47	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process identical protein binding negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
200847_s_at	-0.669	9.716	-3.236	5.455e-03	0.173	-2.129	TMEM66	transmembrane protein 66	8	-30040172	NM_016127	51669	8p12	Hs.521487	10	membrane integral to membrane
206973_at	0.432	4.454	3.236	5.460e-03	0.173	-2.130	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	12	-80177486	NM_003625	8499	12q21.31	Hs.506216	7	protein binding cytoplasm cell-matrix adhesion cell surface
218934_s_at	-0.696	10.768	-3.236	5.461e-03	0.173	-2.130	HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	1	-16213109	NM_014424	27129	1p36.23-p34.3	Hs.502612	7	response to unfolded protein regulation of heart contraction protein C-terminus binding response to heat
241938_at	0.882	7.147	3.235	5.465e-03	0.173	-2.131	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	AA935633	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
201423_s_at	-0.563	8.987	-3.235	5.472e-03	0.173	-2.132	CUL4A	cullin 4A	13	112911086, 112911931	AL037208	8451	13q34	Hs.339735	48	G1/S transition of mitotic cell cycle protein binding DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
230563_at	0.833	4.497	3.234	5.474e-03	0.173	-2.133	RASGEF1A	RasGEF domain family, member 1A	10	-43009989	BF446578	221002	10q11.21	Hs.125293	4	guanyl-nucleotide exchange factor activity intracellular regulation of small GTPase mediated signal transduction
203016_s_at	-0.741	5.926	-3.234	5.482e-03	0.173	-2.134	SSX2IP	synovial sarcoma, X breakpoint 2 interacting protein	1	-84882184	AK001710	117178	1p22.3	Hs.22587	14	protein binding nucleus adherens junction cell adhesion cell junction protein complex	Adherens junction
216082_at	0.405	4.629	3.233	5.495e-03	0.174	-2.136	NEU3	sialidase 3 (membrane sialidase)	11	74377597	AK022450	10825	11q13.5	Hs.191074	25	exo-alpha-sialidase activity plasma membrane integral to plasma membrane carbohydrate metabolic process ganglioside catabolic process metabolic process hydrolase activity, acting on glycosyl bonds	Other glycan degradation Sphingolipid metabolism
226541_at	-0.534	6.966	-3.232	5.503e-03	0.174	-2.138	FBXO30	F-box protein 30	6	-146160964	AI808182	84085	6q24	Hs.421095	8	zinc ion binding modification-dependent protein catabolic process metal ion binding
1569323_at	-0.812	4.935	-3.232	5.507e-03	0.174	-2.138	PTPRG	protein tyrosine phosphatase, receptor type, G	3	61522282	BU853579	5793	3p21-p14	Hs.595541 Hs.654488	19	transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine kinase signaling pathway membrane hydrolase activity identical protein binding
238844_s_at	-0.760	5.808	-3.231	5.515e-03	0.174	-2.139	NPHP1	nephronophthisis 1 (juvenile)	2	-110238202	BF216535	4867	2q13	Hs.280388	36	structural molecule activity protein binding adherens junction signal transduction excretion visual behavior membrane cell-cell adhesion actin cytoskeleton organization cell junction
206461_x_at	-0.773	10.334	-3.229	5.532e-03	0.174	-2.142	MT1H	metallothionein 1H	16	55261226	NM_005951	4496	16q13	Hs.438462	16	copper ion binding protein binding zinc ion binding cadmium ion binding metal ion binding
1569076_a_at	0.444	3.324	3.229	5.537e-03	0.174	-2.143	ZNF836	zinc finger protein 836	19	-57349936	BE791720	162962	19q13.41	Hs.631584	1	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1559926_at	0.678	5.115	3.228	5.544e-03	0.174	-2.144	LOC728353	hypothetical protein LOC728353	14		BC031683	728353	14q11.2	Hs.621210
221600_s_at	0.746	8.954	3.227	5.563e-03	0.175	-2.147	C11orf67	chromosome 11 open reading frame 67	11	77209855	BC002752	28971	11q14.1	Hs.503357	3
209033_s_at	-0.614	9.042	-3.225	5.586e-03	0.175	-2.151	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	21	37661728, 37713076, 37714470, 37714471	D86550	1859	21q22.13	Hs.368240 Hs.719269	57	nucleotide binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding nucleus nervous system development nuclear speck transferase activity peptidyl-tyrosine phosphorylation protein self-association protein amino acid autophosphorylation
213224_s_at	-0.437	6.000	-3.224	5.593e-03	0.176	-2.152	NCRNA00081	non-protein coding RNA 81	10	-112648478, -112648478	AK025724	92482	10q25.2	Hs.232543 Hs.651480	4	cytoplasm cilium
201136_at	-0.813	7.879	-3.224	5.599e-03	0.176	-2.153	PLP2	proteolipid protein 2 (colonic epithelium-enriched)	X	48915216	NM_002668	5355	Xp11.23	Hs.77422	12	protein binding membrane fraction endoplasmic reticulum endoplasmic reticulum membrane plasma membrane ion transport chemotaxis ion transmembrane transporter activity integral to membrane cytokine-mediated signaling pathway chemokine binding
236824_at	-0.315	2.615	-3.223	5.603e-03	0.176	-2.154	TMEM132B	transmembrane protein 132B	12	124377114	AI435595	114795	12q24.31-q24.32	Hs.524838	4	molecular_function cellular_component biological_process membrane integral to membrane
225914_s_at	-0.500	4.879	-3.223	5.606e-03	0.176	-2.154	CAB39L	calcium binding protein 39-like	13	-48780786, -48780786	AW242839	81617	13q14.2	Hs.87159	9	protein binding	mTOR signaling pathway
222279_at	0.420	4.999	3.222	5.612e-03	0.176	-2.155	RP3-377H14.5	hypothetical LOC285830	6	-29802356, -1147069, -949185	AI669379	285830	6p22.1	Hs.646985	2
211684_s_at	-0.423	8.353	-3.222	5.614e-03	0.176	-2.156	DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	2	172252227	AF250307	1781	2q31.1	Hs.546250	17	microtubule motor activity protein binding cytoplasm microtubule microtubule-based movement dynein complex
225731_at	-0.492	5.190	-3.220	5.639e-03	0.176	-2.160	ANKRD50	ankyrin repeat domain 50	4	-125804915	BF196876	57182	4q28.1	Hs.480694	3
209276_s_at	-0.916	9.119	-3.219	5.654e-03	0.176	-2.162	GLRX	glutaredoxin (thioltransferase)	5	-95175308	AF162769	2745	5q14	Hs.28988 Hs.712696	47	cytoplasm cytosol transport electron carrier activity protein disulfide oxidoreductase activity glutathione disulfide oxidoreductase activity electron transport chain cell redox homeostasis protein N-terminus binding
226103_at	-0.444	11.454	-3.218	5.657e-03	0.176	-2.163	NEXN	nexilin (F actin binding protein)	1	78126787	AF114264	91624	1p31.1	Hs.612385	6	cytoplasm cytoskeleton cell-substrate adherens junction cell junction regulation of cell migration actin filament binding regulation of cytoskeleton organization
208799_at	-0.334	10.104	-3.218	5.660e-03	0.176	-2.163	PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	14	-22564900, -22564900	BC004146	5693	14q11.2	Hs.422990	53	threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
204336_s_at	0.480	5.732	3.218	5.667e-03	0.177	-2.164	RGS19	regulator of G-protein signaling 19	20	-62174978, -62174978	NM_005873	10287	20q13.33	Hs.422336	25	signal transducer activity protein binding membrane fraction Golgi apparatus heterotrimeric G-protein complex autophagy G-protein coupled receptor protein signaling pathway small GTPase mediated signal transduction negative regulation of signal transduction membrane
228920_at	0.459	5.963	3.217	5.674e-03	0.177	-2.165	ZNF260	zinc finger protein 260	19	-41693433	BE328273	339324	19q13.12	Hs.18103	5	DNA binding intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
209840_s_at	-1.123	5.365	-3.217	5.677e-03	0.177	-2.166	LRRN3	leucine rich repeat neuronal 3	7	110518297	AI221950	54674	7q31.1	Hs.3781	6	protein binding membrane integral to membrane
219632_s_at	0.613	5.676	3.216	5.684e-03	0.177	-2.167	TRPV1	transient receptor potential cation channel, subfamily V, member 1	17	-3415489, -3415489, -3415489, -3415489	AF196175	7442	17p13.2	Hs.579217 Hs.655380	107	nucleotide binding ion channel activity calcium channel activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ion transport calcium ion transport cell surface receptor linked signal transduction chemosensory behavior thermoception	Neuroactive ligand-receptor interaction
208814_at	-0.662	7.388	-3.215	5.700e-03	0.177	-2.170	HSPA4	heat shock 70kDa protein 4	5	132415560	AA043348	3308	5q31.1-q31.2	Hs.90093	108	nucleotide binding ATP binding nucleus cytoplasm response to unfolded protein cellular chaperone-mediated protein complex assembly mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation
223084_s_at	-0.710	8.721	-3.214	5.704e-03	0.177	-2.170	CCNDBP1	cyclin D-type binding-protein 1	15	41264757, 41265429	AF246144	23582	15q14-q15	Hs.36794 Hs.368642 Hs.688009	19	protein binding nucleus cytoplasm cell cycle
214553_s_at	-0.668	9.327	-3.214	5.707e-03	0.177	-2.171	ARPP19	cAMP-regulated phosphoprotein, 19kDa	15	-50626723	NM_006628	10776	15q21.2	Hs.512908	10	receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import
204979_s_at	-0.431	11.743	-3.213	5.720e-03	0.177	-2.173	SH3BGR	SH3 domain binding glutamic acid-rich protein	21	39739666, 39745649	NM_007341	6450	21q22.3	Hs.473847	8	SH3/SH2 adaptor activity cytosol protein complex assembly SH3 domain binding
209804_at	-0.790	5.084	-3.213	5.725e-03	0.177	-2.174	DCLRE1A	DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)	10	-115584473	D42045	9937	10q25.1	Hs.1560	14	nucleus nucleotide-excision repair response to DNA damage stimulus cell cycle mitosis cell division
227054_at	0.361	7.055	3.213	5.727e-03	0.177	-2.174	N6AMT2	N-6 adenine-specific DNA methyltransferase 2 (putative)	13	-20201072	AI141584	221143	13q12.11	Hs.26674	3	nucleic acid binding methyltransferase activity transferase activity methylation
1557720_s_at	1.202	4.018	3.212	5.735e-03	0.177	-2.175	MYO16	myosin XVI	13	108046500	BC041343	23026	13q33.3	Hs.656587	7	nucleotide binding motor activity ATP binding nucleoplasm cytoplasm plasma membrane negative regulation of cell proliferation myosin complex cerebellum development negative regulation of S phase of mitotic cell cycle perinuclear region of cytoplasm actin filament binding
209147_s_at	-0.535	9.090	-3.212	5.736e-03	0.177	-2.175	PPAP2A	phosphatidic acid phosphatase type 2A	5	-54756439	AB000888	8611	5q11	Hs.696231	20	membrane fraction cytosol plasma membrane integral to plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity negative regulation of cell proliferation germ cell migration hydrolase activity regulation of lipid metabolic process androgen receptor signaling pathway phospholipid dephosphorylation	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
1556839_s_at	0.641	4.206	3.211	5.747e-03	0.178	-2.177	SPTBN5	spectrin, beta, non-erythrocytic 5	15	-39927635	AA515490	51332	15q21	Hs.709819	3	actin binding cytoplasm cytoskeleton spectrin membrane actin cytoskeleton organization actin filament capping
205202_at	-0.528	10.257	-3.209	5.768e-03	0.178	-2.180	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	6	150112523	NM_005389	5110	6q24-q25	Hs.279257	25	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding
210596_at	-0.411	6.170	-3.209	5.774e-03	0.178	-2.181	MAGT1	magnesium transporter 1	X	-76968519	AF130104	84061	Xq21.1	Hs.323562 Hs.710189	14	dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum oligosaccharyltransferase complex membrane integral to membrane protein amino acid N-linked glycosylation via asparagine
213860_x_at	-0.580	8.864	-3.207	5.791e-03	0.178	-2.184	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	AW268585	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
209034_at	-0.604	10.368	-3.207	5.794e-03	0.178	-2.185	PNRC1	proline-rich nuclear receptor coactivator 1	6	89847147	AF279899	10957	6q15	Hs.703798 Hs.75969	11	protein binding nucleus regulation of transcription
220185_at	0.437	5.760	3.207	5.795e-03	0.178	-2.185	SPTBN4	spectrin, beta, non-erythrocytic 4	19	45664965, 45728234	NM_025213	57731	19q13.13	Hs.32706	11	actin binding structural constituent of cytoskeleton protein binding cytoplasm cytoskeleton cell cortex cytoskeletal anchoring at plasma membrane axonogenesis sensory perception of sound adult walking behavior spectrin fertilization vesicle-mediated transport nuclear matrix PML body transmission of nerve impulse axon ankyrin binding adult behavior positive regulation of multicellular organism growth axon hillock actin filament capping
1554579_a_at	-0.744	8.489	-3.207	5.797e-03	0.178	-2.185	MYO18B	myosin XVIIIB	22	24468119	AB042648	84700	22q11.2-q12.1	Hs.417959	11	nucleotide binding motor activity actin binding protein binding ATP binding nucleus cytoplasm unconventional myosin complex sarcomere
217841_s_at	-0.358	7.156	-3.206	5.800e-03	0.178	-2.185	PPME1	protein phosphatase methylesterase 1	11	73560015	NM_016147	51400	11q13.4	Hs.503251	10	carboxylesterase activity phosphoprotein phosphatase inhibitor activity protein amino acid demethylation protein phosphatase type 2A regulator activity hydrolase activity protein phosphatase 2A binding protein C-terminal methylesterase activity	Tropane, piperidine and pyridine alkaloid biosynthesis
201316_at	-0.647	8.090	-3.206	5.805e-03	0.178	-2.186	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	7	-42922986	AL523904	5683	7p13	Hs.333786	48	threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
212999_x_at	0.615	4.201	3.206	5.806e-03	0.178	-2.186	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	AW276186	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
203781_at	0.350	11.411	3.205	5.813e-03	0.179	-2.188	MRPL33	mitochondrial ribosomal protein L33	2	27848087	NM_004891	9553	2p21	Hs.515879	8	structural constituent of ribosome intracellular mitochondrion ribosome translation
244861_at	0.342	6.374	3.205	5.816e-03	0.179	-2.188	ZNF527	zinc finger protein 527	19	42553898	AI679883	84503	19q13.1	Hs.590940	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226222_at	-0.477	5.512	-3.205	5.818e-03	0.179	-2.188	KIAA1432	KIAA1432	9	5619326, 5646582	AB037853	57589	9p24.1	Hs.211520	5	membrane integral to membrane
213012_at	-1.098	7.748	-3.204	5.824e-03	0.179	-2.189	NEDD4	neural precursor cell expressed, developmentally down-regulated 4	15	-53906413, -53906413	D42055	4734	15q	Hs.1565	79	ubiquitin ligase complex chromatin ubiquitin-protein ligase activity intracellular membrane fraction cytoplasm cytosol plasma membrane cell cortex protein modification process protein targeting to lysosome pathogenesis negative regulation of sodium ion transport negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage positive regulation of phosphoinositide 3-kinase cascade apicolateral plasma membrane ligase activity acid-amino acid ligase activity transmission of virus sodium channel inhibitor activity protein domain specific binding modification-dependent protein catabolic process neuron projection development receptor internalization beta-2 adrenergic receptor binding receptor catabolic process cellular response to UV protein ubiquitination during ubiquitin-dependent protein catabolic process glucocorticoid receptor signaling pathway ubiquitin binding ubiquitin binding positive regulation of protein catabolic process positive regulation of nucleocytoplasmic transport perinuclear region of cytoplasm phosphoserine binding phosphothreonine binding progesterone receptor signaling pathway response to calcium ion RNA polymerase binding proline-rich region binding	Ubiquitin mediated proteolysis Endocytosis
235953_at	0.691	4.455	3.204	5.827e-03	0.179	-2.190	ZNF610	zinc finger protein 610	19	57531309, 57540493	AA776810	162963	19q13.41	Hs.357663	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208853_s_at	-0.595	6.394	-3.204	5.834e-03	0.179	-2.191	CANX	calnexin	5	179058535	L18887	821	5q35	Hs.699155	90	calcium ion binding sugar binding endoplasmic reticulum protein folding protein secretion membrane integral to membrane melanosome unfolded protein binding	Antigen processing and presentation
213479_at	-0.785	4.185	-3.203	5.837e-03	0.179	-2.191	NPTX2	neuronal pentraxin II	7	98084532	U26662	4885	7q21.3-q22.1	Hs.3281	13	molecular_function calcium ion binding sugar binding extracellular region synaptic transmission
227702_at	-0.896	5.832	-3.203	5.842e-03	0.179	-2.192	CYP4X1	cytochrome P450, family 4, subfamily X, polypeptide 1	1	47261826	AA557324	260293	1p33	Hs.439760	7	monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity
202824_s_at	-0.343	10.120	-3.203	5.843e-03	0.179	-2.192	TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8	-75021187	NM_005648	6921	8q21.11	Hs.554594	46	protein binding nucleus nucleoplasm cytosol regulation of transcription from RNA polymerase II promoter ubiquitin-dependent protein catabolic process interspecies interaction between organisms regulation of transcription	Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma
212297_at	-0.460	5.468	-3.203	5.844e-03	0.179	-2.192	ATP13A3	ATPase type 13A3	3	-195604691	BF218804	79572	3q29	Hs.529609	11	nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity
1552344_s_at	-0.899	6.052	-3.202	5.848e-03	0.179	-2.193	CNOT7	CCR4-NOT transcription complex, subunit 7	8	-17133392, -17131110	NM_054026	29883	8p22-p21.3	Hs.645009 Hs.719129	19	nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter	RNA degradation
214074_s_at	-0.482	5.140	-3.201	5.870e-03	0.179	-2.196	CTTN	cortactin	11	69922259, 69922291	BG475299	2017	11q13	Hs.596164	106	ruffle protein binding soluble fraction cytoplasm cytoskeleton cell cortex lamellipodium	Tight junction Pathogenic Escherichia coli infection - EHEC
209984_at	-0.357	5.759	-3.199	5.894e-03	0.180	-2.200	KDM4C	lysine (K)-specific demethylase 4C	9	6710862, 6747640, 6747640, 6747640	AB037901	23081	9p24.1	Hs.709425	15	molecular_function nucleic acid binding iron ion binding protein binding cellular_component nucleus biological_process zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
238929_at	-0.452	5.174	-3.198	5.899e-03	0.180	-2.201	SFRS2B	splicing factor, arginine/serine-rich 2B	11	94439703	N30132	10929	11q22	Hs.476680 Hs.713908	6	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
213571_s_at	-0.573	7.408	-3.197	5.915e-03	0.180	-2.203	EIF4E2	eukaryotic translation initiation factor 4E family member 2	2	233123600	BF516289	9470	2q37.1	Hs.292026 Hs.700929	15	RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation	mTOR signaling pathway Insulin signaling pathway
202201_at	0.675	8.887	3.196	5.929e-03	0.180	-2.206	BLVRB	biliverdin reductase B (flavin reductase (NADPH))	19	-45645530	NM_000713	645	19q13.1-q13.2	Hs.515785	14	biliverdin reductase activity binding cytoplasm oxidoreductase activity flavin reductase activity cellular metabolic process coenzyme binding oxidation reduction	Porphyrin and chlorophyll metabolism
225138_at	-0.684	7.678	-3.195	5.934e-03	0.180	-2.206	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	N52625	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
213519_s_at	-0.509	6.327	-3.193	5.959e-03	0.181	-2.210	LAMA2	laminin, alpha 2	6	129245978	AI078169	3908	6q22-q23	Hs.200841	40	receptor binding structural molecule activity extracellular region basal lamina laminin-1 complex muscle organ development regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission, cholinergic sarcolemma regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
204362_at	0.978	6.645	3.192	5.968e-03	0.181	-2.212	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	NM_003930	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
200792_at	-0.575	9.536	-3.192	5.978e-03	0.181	-2.213	XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	22	40347240	NM_001469	2547	22q13.2-q13.31	Hs.292493	155	nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding membrane fraction nucleus nucleoplasm transcription factor complex chromosome cytoplasm DNA-dependent protein kinase-DNA ligase 4 complex DNA ligation double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding response to ionizing radiation positive regulation of specific transcription from RNA polymerase II promoter promoter binding transcription activator activity hydrolase activity provirus integration initiation of viral infection V(D)J recombination positive regulation of transcription, DNA-dependent positive regulation of neurogenesis	Non-homologous end-joining
209046_s_at	-0.430	10.852	-3.192	5.979e-03	0.181	-2.213	GABARAPL2	GABA(A) receptor-associated protein-like 2	16	74157749	AB030710	11345	16q22.3-q24.1	Hs.461379	20	Golgi membrane SNARE binding autophagic vacuole membrane intracellular membrane fraction Golgi apparatus cytosol intra-Golgi vesicle-mediated transport autophagy microtubule binding protein transport positive regulation of ATPase activity beta-tubulin binding GABA receptor binding GABA receptor binding ATPase binding	Regulation of autophagy
228239_at	-0.574	5.726	-3.191	5.985e-03	0.181	-2.214	FAM165B	family with sequence similarity 165, member B	21	34669618	AA148789	54065	21q22.12	Hs.656195	7	molecular_function cellular_component biological_process membrane integral to membrane
232705_at	-0.394	5.265	-3.191	5.989e-03	0.181	-2.215	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	AK025207	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
230030_at	-2.007	4.863	-3.191	5.991e-03	0.181	-2.215	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	X	-131587718	AI767756	90161	Xq26.2	Hs.385956	7	sulfotransferase activity membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
222231_s_at	-0.509	6.555	-3.190	5.995e-03	0.181	-2.216	LRRC59	leucine rich repeat containing 59	17	-45813597	AK025328	55379	17q21.33	Hs.370927	6	protein binding endoplasmic reticulum microsome membrane integral to membrane mitochondrial nucleoid
212355_at	-0.595	5.427	-3.190	5.998e-03	0.181	-2.216	KIAA0323	KIAA0323	14	23968980	AI075450	23351	14q12	Hs.713590	5
1555271_a_at	0.388	5.059	3.189	6.010e-03	0.181	-2.218	TERT	telomerase reverse transcriptase	5	-1306286	AB085628	7015	5p15.33	Hs.492203	518	telomere maintenance chromosome, telomeric region nuclear telomere cap complex DNA binding telomeric template RNA reverse transcriptase activity protein binding nucleus nucleoplasm chromosome telomerase holoenzyme complex anti-apoptosis telomere maintenance via telomerase senescence transferase activity nucleotidyltransferase activity DNA strand elongation telomere formation via telomerase telomeric DNA binding protein homodimerization activity telomeric RNA binding
227930_at	-0.623	7.574	-3.187	6.037e-03	0.182	-2.222	EIF2C4	eukaryotic translation initiation factor 2C, 4	1	36046414	AI669957	192670	1p34.3	Hs.471492	8	cytoplasmic mRNA processing body RNA binding protein binding cytoplasm mRNA catabolic process regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation
226364_at	0.461	5.856	3.186	6.043e-03	0.182	-2.223	HIP1	huntingtin interacting protein 1	7	-75001344	AU145049	3092	7q11.23	Hs.329266 Hs.619089	31	actin binding structural constituent of cytoskeleton membrane fraction nucleus cytoplasm Golgi apparatus cytoskeleton endocytosis induction of apoptosis activation of caspase activity cell death membrane cell differentiation clathrin binding clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding regulation of apoptosis regulation of transcription positive regulation of receptor-mediated endocytosis clathrin coat assembly	Huntington's disease
225244_at	-0.412	7.264	-3.186	6.046e-03	0.182	-2.223	SNAP47	synaptosomal-associated protein, 47kDa	1	225989319	AA019893	116841	1q42.13	Hs.325081	3	cytoplasm membrane perinuclear region of cytoplasm	SNARE interactions in vesicular transport
227388_at	-0.661	7.954	-3.185	6.056e-03	0.182	-2.225	TUSC1	tumor suppressor candidate 1	9	-25666386	AA479016	286319	9p21.2	Hs.26268 Hs.606014	2
1555154_a_at	-0.786	6.750	-3.185	6.058e-03	0.182	-2.225	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	AF142421	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
1557910_at	-0.721	8.999	-3.184	6.072e-03	0.182	-2.227	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	6	44322826	BG612458	3326	6p12	Hs.509736 Hs.689683 Hs.701787	50	nucleotide binding ATP binding cytoplasm protein folding response to unfolded protein nitric-oxide synthase regulator activity TPR domain binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process melanosome positive regulation of nitric oxide biosynthetic process unfolded protein binding regulation of interferon-gamma-mediated signaling pathway regulation of type I interferon-mediated signaling pathway	Antigen processing and presentation Pathways in cancer Prostate cancer
226734_at	-0.711	6.631	-3.184	6.074e-03	0.182	-2.228	EIF4E2	eukaryotic translation initiation factor 4E family member 2	2	233123600	AW242220	9470	2q37.1	Hs.292026 Hs.700929	15	RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation	mTOR signaling pathway Insulin signaling pathway
211536_x_at	-0.364	5.661	-3.184	6.076e-03	0.182	-2.228	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AB009358	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
209621_s_at	-0.788	12.315	-3.183	6.089e-03	0.182	-2.230	PDLIM3	PDZ and LIM domain 3	4	-186659844	AF002280	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
218876_at	-1.408	6.526	-3.182	6.094e-03	0.182	-2.231	TPPP3	tubulin polymerization-promoting protein family member 3	16	-65981212	NM_016140	51673	16q22.1	Hs.534458	8
219816_s_at	-0.358	7.003	-3.181	6.115e-03	0.183	-2.234	RBM23	RNA binding motif protein 23	14	-22439693	NM_018107	55147	14q11.2	Hs.4997	11	nucleotide binding RNA binding nucleus nucleolus mRNA processing
228986_at	-0.862	3.773	-3.181	6.116e-03	0.183	-2.234	OSBPL8	oxysterol binding protein-like 8	12	-75269708	AW978375	114882	12q14	Hs.430849	13	lipid transport steroid metabolic process
238497_at	0.342	3.491	3.180	6.118e-03	0.183	-2.234	TMEM136	transmembrane protein 136	11	119701225	N51836	219902	11q23.3	Hs.706896	1	membrane integral to membrane
222559_s_at	-0.612	7.323	-3.180	6.123e-03	0.183	-2.235	RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	18	-31823789	T79568	55197	18q12.2	Hs.464912	3
213463_s_at	-0.439	6.371	-3.180	6.124e-03	0.183	-2.235	FAM149B1	family with sequence similarity 149, member B1	10	74597882	AW300504	317662	10q22.2	Hs.408577	4
229296_at	0.383	4.045	3.180	6.124e-03	0.183	-2.235	LOC100128501	hypothetical protein LOC100128501	9		AI659477	100128501	9q34.11	Hs.711775	1
211476_at	-1.518	8.067	-3.180	6.129e-03	0.183	-2.236	MYOZ2	myozenin 2	4	120276386	AY013295	51778	4q26-q27	Hs.381047	16	protein binding cytoplasm biological_process actin cytoskeleton sarcomere Z disc protein phosphatase 2B binding
1555083_at	0.311	6.198	3.180	6.130e-03	0.183	-2.236	RPL13AP17	ribosomal protein L13a pseudogene 17	7	77814494	BC027852	399670	7q21.11	Hs.568045	3
213737_x_at	0.378	8.885	3.179	6.138e-03	0.183	-2.237	GOLGA9P	golgi autoantigen, golgin subfamily a, 9 pseudogene	15	20806682	AI620911	283796	15q11.2	Hs.375441	2
229940_at	-0.522	5.675	-3.179	6.140e-03	0.183	-2.238	SETD3	SET domain containing 3	14	-98945893, -98933835	BF448048	84193	14q32.2	Hs.510407	6
227339_at	-0.364	5.458	-3.178	6.145e-03	0.183	-2.238	RGMB	RGM domain family, member B	5	98132898	BE206621	285704	5q15	Hs.526902	5	ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane
212261_at	-0.276	7.311	-3.177	6.159e-03	0.183	-2.240	GIGYF2	GRB10 interacting GYF protein 2	2	233270258	AB014542	26058	2q37.1	Hs.565319	23	protein binding
244345_at	0.353	2.913	3.175	6.187e-03	0.184	-2.244	CADM1	cell adhesion molecule 1	11	-114549554	AI627453	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
217833_at	-0.708	8.199	-3.174	6.194e-03	0.184	-2.245	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	AL520908	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
225812_at	0.648	6.637	3.174	6.206e-03	0.184	-2.247	C6orf225	chromosome 6 open reading frame 225	6	112515366	N36759	619208	6q21	Hs.591340	1
227251_at	-0.490	8.734	-3.173	6.210e-03	0.184	-2.248	DCAF5	DDB1 and CUL4 associated factor 5	14	-68587390	AI431597	8816	14q23-q24.1	Hs.509780	6
205459_s_at	0.449	5.769	3.173	6.213e-03	0.184	-2.248	NPAS2	neuronal PAS domain protein 2	2	100803044	NM_002518	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
224096_at	0.405	5.557	3.173	6.216e-03	0.184	-2.249	LOC100130797	PRO0566	20		AF116649	100130797	20q11.22	Hs.711049
220935_s_at	-0.388	6.696	-3.172	6.220e-03	0.184	-2.249	CDK5RAP2	CDK5 regulatory subunit associated protein 2	9	-122190967	NM_018249	55755	9q33.2	Hs.269560	18	centrosome cytoskeleton brain development microtubule binding neuronal Cdc2-like kinase binding regulation of neuron differentiation
202558_s_at	-0.453	4.897	-3.172	6.221e-03	0.184	-2.249	HSPA13	heat shock protein 70kDa family, member 13	21	-14665307	NM_006948	6782	21q11 21q11.1	Hs.352341	16	nucleotide binding ATP binding endoplasmic reticulum microsome
200722_s_at	-0.398	6.363	-3.172	6.231e-03	0.184	-2.251	CAPRIN1	cell cycle associated protein 1	11	34029805, 34029805	BG258784	4076	11p13	Hs.471818	10	protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection
220419_s_at	-0.664	9.493	-3.171	6.240e-03	0.184	-2.252	USP25	ubiquitin specific peptidase 25	21	16024366	NM_013396	29761	21q11.2	Hs.473370	11	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
224311_s_at	-1.104	5.702	-3.171	6.242e-03	0.184	-2.252	CAB39	calcium binding protein 39	2	231285800, 231286506	AF151824	51719	2q37.1	Hs.632536	14	protein binding cytoplasm	mTOR signaling pathway
211376_s_at	-0.286	6.571	-3.170	6.249e-03	0.184	-2.254	NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	10	-123706592	BC005212	54780	10q26.13	Hs.258798	8
203547_at	0.377	6.362	3.169	6.259e-03	0.184	-2.255	CD4	CD4 molecule	12	6768911	U47924	920	12pter-p12	Hs.631659	992	conjugation with cellular fusion cytokine production glycoprotein binding transmembrane receptor activity extracellular matrix structural constituent early endosome endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane plasma membrane protein amino acid N-linked glycosylation immune response cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway zinc ion binding external side of plasma membrane coreceptor activity integral to membrane initiation of viral infection protein kinase binding T cell receptor complex MHC class II protein binding protein homodimerization activity interspecies interaction between organisms T cell selection positive regulation of interleukin-2 biosynthetic process membrane raft positive regulation of protein kinase activity positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of T cell activation response to protein stimulus	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage T cell receptor signaling pathway Primary immunodeficiency
210759_s_at	-0.330	9.928	-3.169	6.269e-03	0.184	-2.256	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	11	-14492087, -14482998, -14482998	M64992	5682	11p15.1	Hs.102798 Hs.445711	52	RNA binding threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex polysome ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
200768_s_at	-0.428	8.543	-3.169	6.270e-03	0.184	-2.257	MAT2A	methionine adenosyltransferase II, alpha	2	85619798	BC001686	4144	2p11.2	Hs.516157	18	nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
221535_at	-0.449	6.843	-3.168	6.277e-03	0.184	-2.258	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	3	-195842806	AL136897	55341	3q29	Hs.518505	12	nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export
210774_s_at	-0.468	10.935	-3.168	6.280e-03	0.184	-2.258	NCOA4	nuclear receptor coactivator 4	10	51235113, 51242369, 51246290	AL162047	8031	10q11.2	Hs.643658 Hs.709644	43	transcription coactivator activity protein binding nucleus male gonad development androgen receptor signaling pathway regulation of transcription positive regulation of transcription, DNA-dependent androgen receptor binding	Pathways in cancer Thyroid cancer
202846_s_at	-0.477	6.658	-3.167	6.292e-03	0.185	-2.260	PIGC	phosphatidylinositol glycan anchor biosynthesis, class C	1	-170677219	NM_002642	5279	1q23-q25	Hs.188456	12	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring glycosyl groups phosphatidylinositol N-acetylglucosaminyltransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
226083_at	-1.033	7.027	-3.165	6.311e-03	0.185	-2.262	TMEM70	transmembrane protein 70	8	75050983	AA886902	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
212392_s_at	-1.171	6.396	-3.165	6.320e-03	0.185	-2.264	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	AI950145	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
212041_at	-0.535	8.805	-3.164	6.323e-03	0.185	-2.264	ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	16	-66029417	AL566172	9114	16q22	Hs.106876	21	protein binding ion transport hydrogen-exporting ATPase activity, phosphorylative mechanism ATP synthesis coupled proton transport proton transport membrane vacuolar proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V0 domain	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
226902_at	-0.543	10.746	-3.164	6.327e-03	0.185	-2.265	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	3	180853626	BF109140	8975	3q26.2-q26.3	Hs.175322	11	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding
215505_s_at	-0.786	5.422	-3.164	6.329e-03	0.185	-2.265	STRN3	striatin, calmodulin binding protein 3	14	-30432755	AF243424	29966	14q13-q21	Hs.21016 Hs.401843	13	calmodulin binding membrane fraction nucleus cytoplasm cytosol cell cycle membrane
203115_at	-0.792	5.892	-3.164	6.332e-03	0.185	-2.266	FECH	ferrochelatase (protoporphyria)	18	-53363070	AU152635	2235	18q21.3	Hs.365365	61	ferrochelatase activity ferrochelatase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix generation of precursor metabolites and energy heme biosynthetic process ferrous iron binding response to light stimulus detection of UV membrane protoporphyrinogen IX metabolic process metal ion binding 2 iron, 2 sulfur cluster binding	Porphyrin and chlorophyll metabolism Metabolic pathways
215711_s_at	-0.703	5.266	-3.163	6.336e-03	0.185	-2.266	WEE1	WEE1 homolog (S. pombe)	11	9551803, 9552809	AJ277546	7465	11p15.3-p15.1	Hs.249441	61	nucleotide binding magnesium ion binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division	Cell cycle
1552731_at	-1.674	8.049	-3.162	6.357e-03	0.186	-2.269	ABRA	actin-binding Rho activating protein	8	-107840886	NM_139166	137735	8q23.1	Hs.374668	12	protein import into nucleus, translocation transcription coactivator activity actin binding cytoplasm plasma membrane protein transport actin cytoskeleton sarcomere positive regulation of Rho protein signal transduction positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription factor activity intracellular protein transmembrane transport
222130_s_at	-0.492	6.905	-3.159	6.389e-03	0.186	-2.274	FTSJ2	FtsJ homolog 2 (E. coli)	7	-2240451	AK024635	29960	7p22	Hs.279877	4	nucleic acid binding nucleus nucleolus rRNA processing RNA methyltransferase activity transferase activity rRNA methylation methylation
1552767_a_at	-1.989	5.544	-3.159	6.391e-03	0.186	-2.274	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	X	-131587718	NM_147174	90161	Xq26.2	Hs.385956	7	sulfotransferase activity membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
219874_at	0.384	4.129	3.159	6.393e-03	0.186	-2.274	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8	3	-126284169	NM_024628	84561	3q21.2	Hs.658514	7	ion transport potassium ion transport symporter activity membrane integral to membrane potassium ion binding chloride ion binding
208640_at	-0.431	10.558	-3.159	6.398e-03	0.186	-2.275	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	BG292367	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
201408_at	-0.749	9.614	-3.159	6.398e-03	0.186	-2.275	PPP1CB	protein phosphatase 1, catalytic subunit, beta isoform	2	28828117, 28828129	W67887	5500	2p23	Hs.591571 Hs.702907	42	protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding cell division MLL5-L complex	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton Insulin signaling pathway
1562799_at	0.360	5.444	3.158	6.413e-03	0.186	-2.277	LOC100130285	hypothetical LOC100130285	16		AK097604	100130285	16p13.3	Hs.683811	1
234284_at	0.311	3.864	3.158	6.413e-03	0.186	-2.277	GNG8	guanine nucleotide binding protein (G protein), gamma 8	19	-51829172	AF188179	94235	19q13.2-q13.3	Hs.283961	5	GTPase activity signal transducer activity extracellular region heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
228829_at	-0.760	6.651	-3.157	6.416e-03	0.186	-2.278	ATF7	activating transcription factor 7	12	-52192109, -52192109	AI279868	11016	12q13	Hs.12286	18	transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding protein dimerization activity
227379_at	0.541	5.055	3.157	6.419e-03	0.186	-2.278	MBOAT1	membrane bound O-acyltransferase domain containing 1	6	-20208913	AI734993	154141	6p22.3	Hs.377830	7	acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
230129_at	-0.577	5.099	-3.157	6.420e-03	0.186	-2.278	PSTK	phosphoseryl-tRNA kinase	10	124729545	BF589448	118672	10q26.13	Hs.281004	4	nucleotide binding magnesium ion binding ATP binding translation kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor	Aminoacyl-tRNA biosynthesis
218955_at	-0.370	7.480	-3.156	6.434e-03	0.186	-2.280	BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	8	-37820560	NM_018310	55290	8p11.23	Hs.709301	11	protein binding nucleus transcription factor complex transcription initiation regulation of transcription, DNA-dependent zinc ion binding transcription regulator activity metal ion binding
210896_s_at	-0.528	5.196	-3.155	6.442e-03	0.187	-2.281	ASPH	aspartate beta-hydroxylase	8	-62739837, -62699648, -62699648, -62575669	AF306765	444	8q12.1	Hs.591874	24	peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis
1552430_at	0.296	2.228	3.155	6.450e-03	0.187	-2.282	WDR17	WD repeat domain 17	4	177224125	NM_170710	116966	4q34	Hs.532056	3
217365_at	0.329	4.164	3.154	6.455e-03	0.187	-2.283	PRAMEF11	PRAME family member 11	1	-12807054	AL022101	440560	1p36.21	Hs.551617	2
226607_at	-0.977	8.310	-3.154	6.458e-03	0.187	-2.283	C20orf194	chromosome 20 open reading frame 194	20	-3177947	AI498144	25943	20p13	Hs.516853	7
236328_at	0.415	4.744	3.154	6.463e-03	0.187	-2.284	ZNF285A	zinc finger protein 285A	19	-49581647	AW513227	26974		Hs.709428	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207968_s_at	-0.976	6.288	-3.154	6.467e-03	0.187	-2.285	MEF2C	myocyte enhancer factor 2C	5	-88049814, -88049814	NM_002397	4208	5q14	Hs.653394	56	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development negative regulation of specific transcription from RNA polymerase II promoter nuclear speck cell differentiation sequence-specific DNA binding positive regulation of survival gene product expression	MAPK signaling pathway
210622_x_at	-0.357	5.865	-3.153	6.470e-03	0.187	-2.285	CDK10	cyclin-dependent kinase 10	16	88280576	AF153430	8558	16q24	Hs.699177	16	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation traversing start control point of mitotic cell cycle negative regulation of cell proliferation transferase activity
224385_s_at	0.273	3.337	3.153	6.477e-03	0.187	-2.286	MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)	22	48870561, 48870811, 48927610	AF285604	54456	22q13.33	Hs.62880	7	nucleotide binding magnesium ion binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding intracellular multicellular organismal development germ cell development spermatogenesis muscle organ development cell proliferation hydrolase activity negative regulation of cell cycle
203810_at	-0.825	8.517	-3.153	6.479e-03	0.187	-2.286	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1	78243223	BG252490	11080	1p31.1	Hs.13852	11	protein folding response to unfolded protein response to heat heat shock protein binding unfolded protein binding
202174_s_at	-0.532	9.124	-3.148	6.537e-03	0.188	-2.295	PCM1	pericentriolar material 1	8	17824645	NM_006197	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
1554217_a_at	-0.548	2.834	-3.148	6.540e-03	0.188	-2.295	CCDC132	coiled-coil domain containing 132	7	92699588, 92699588	BC017888	55610	7q21.3	Hs.222282	5
201944_at	-0.496	7.742	-3.148	6.541e-03	0.188	-2.295	HEXB	hexosaminidase B (beta polypeptide)	5	74016724	NM_000521	3074	5q13	Hs.69293	66	skeletal system development acrosomal vesicle hydrolase activity, hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity lysosome carbohydrate metabolic process glycosphingolipid metabolic process ganglioside catabolic process cellular calcium ion homeostasis lysosome organization penetration of zona pellucida sensory perception of sound locomotory behavior male courtship behavior metabolic process phospholipid biosynthetic process oligosaccharide catabolic process membrane lipid storage sexual reproduction glycosaminoglycan metabolic process regulation of cellular metabolic process myelination protein homodimerization activity cation binding cellular protein metabolic process protein heterodimerization activity oogenesis neuromuscular process controlling balance	Other glycan degradation Amino sugar and nucleotide sugar metabolism Glycosaminoglycan degradation Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways Lysosome
227395_at	-0.825	5.119	-3.147	6.548e-03	0.188	-2.296	TBCEL	tubulin folding cofactor E-like	11	120400012, 120400022	BE672045	219899	11q23.3	Hs.504136	4	cytoplasm cytoskeleton
208818_s_at	-0.661	8.197	-3.147	6.556e-03	0.188	-2.297	COMT	catechol-O-methyltransferase	22	18309262, 18318459, 18319044, 18330069	BC000419	1312	22q11.21 22q11.21-q11.23	Hs.370408 Hs.704514 Hs.713616	742	magnesium ion binding protein binding soluble fraction cytoplasm microsome cytosol plasma membrane catecholamine metabolic process integral to membrane catechol O-methyltransferase activity catechol O-methyltransferase activity transferase activity neurotransmitter catabolic process dopamine catabolic process	Tyrosine metabolism Betalain biosynthesis Metabolic pathways
222918_at	-0.630	7.490	-3.145	6.578e-03	0.188	-2.300	RAB9B	RAB9B, member RAS oncogene family	X	-102966606	AL139228	51209	Xq22.1-q22.3	Hs.522736 Hs.679046	5	nucleotide binding protein binding GTP binding cellular_component plasma membrane Golgi to endosome transport small GTPase mediated signal transduction protein transport
203442_x_at	0.421	5.518	3.145	6.578e-03	0.188	-2.300	EML3	echinoderm microtubule associated protein like 3	11	-62126266	AA478965	256364	11q12.3	Hs.379785	8	protein binding cytoplasm microtubule
230588_s_at	-1.023	5.660	-3.145	6.582e-03	0.188	-2.301	LOC285074	anaphase promoting complex subunit 1 pseudogene	2	-87111310	AA906142	285074	2p11.2	Hs.424184	2
225391_at	-0.679	6.747	-3.145	6.585e-03	0.188	-2.301	LOC93622	hypothetical LOC93622	4		AL562398	93622	4p16.1	Hs.705429	1
201947_s_at	-0.534	8.984	-3.144	6.593e-03	0.189	-2.302	CCT2	chaperonin containing TCP1, subunit 2 (beta)	12	68265474	NM_006431	10576	12q15	Hs.189772	19	nucleotide binding ATP binding nucleus nucleolus cytoplasm cytosol chaperonin-containing T-complex protein folding unfolded protein binding
213947_s_at	0.292	6.219	3.143	6.607e-03	0.189	-2.304	NUP210	nucleoporin 210kDa	3	-13332736	AI867102	23225	3p25.1	Hs.475525	24	protein binding nucleus nuclear pore endoplasmic reticulum protein transport membrane integral to membrane mRNA transport intracellular protein transmembrane transport
229452_at	0.459	7.104	3.143	6.611e-03	0.189	-2.305	TMEM88	transmembrane protein 88	17	7699108	AL544576	92162	17p13.1	Hs.389669	2	membrane integral to membrane
220761_s_at	-0.454	6.337	-3.142	6.620e-03	0.189	-2.306	TAOK3	TAO kinase 3	12	-117071988	NM_016281	51347	12q	Hs.644420	10	nucleotide binding protein serine/threonine kinase activity protein kinase inhibitor activity ATP binding cytoplasm mitochondrion plasma membrane transferase activity negative regulation of JNK cascade positive regulation of JNK cascade protein amino acid autophosphorylation	MAPK signaling pathway
213753_x_at	-0.612	8.952	-3.141	6.639e-03	0.189	-2.309	EIF5A	eukaryotic translation initiation factor 5A	17	7151041, 7151579, 7152011, 7152417	BF541557	1984	17p13-p12	Hs.534314	52	RNA binding translation initiation factor activity translation elongation factor activity nucleus annulate lamellae nuclear pore cytoplasm endoplasmic reticulum cytosol mRNA export from nucleus translation translational frameshifting protein export from nucleus nucleocytoplasmic transport nucleocytoplasmic transport induction of apoptosis cell proliferation peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine protein transport membrane U6 snRNA binding viral genome replication ribosome binding positive regulation of translational elongation positive regulation of translational termination positive regulation of translational initiation protein N-terminus binding intracellular protein transmembrane transport
1569157_s_at	0.803	4.499	3.141	6.640e-03	0.189	-2.309	ZNF846	zinc finger protein 846	19	-9729150	BC037359	162993	19p13.2	Hs.665717	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
238635_at	0.360	2.314	3.141	6.640e-03	0.189	-2.309	C5orf28	chromosome 5 open reading frame 28	5	-43480110	W72333	64417	5p12	Hs.558531	5	membrane integral to membrane
221755_at	-0.454	7.999	-3.140	6.642e-03	0.189	-2.309	EHBP1L1	EH domain binding protein 1-like 1	11	65100084	BG334196	254102	11q13.1	Hs.502867	4
209759_s_at	0.509	9.160	3.140	6.645e-03	0.189	-2.309	DCI	dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)	16	-2229898	BC002746	1632	16p13.3	Hs.403436	6	dodecenoyl-CoA delta-isomerase activity mitochondrion mitochondrial inner membrane mitochondrial matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process isomerase activity	Fatty acid metabolism
221733_s_at	0.324	4.038	3.139	6.659e-03	0.189	-2.311	GPATCH4	G patch domain containing 4	1	-154830902	BE546897	54865	1q22	Hs.193832 Hs.708599	3	nucleic acid binding intracellular
216304_x_at	-0.410	9.276	-3.139	6.661e-03	0.189	-2.312	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AJ295618	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
218472_s_at	-0.512	7.188	-3.139	6.668e-03	0.189	-2.313	PELO	pelota homolog (Drosophila)	5	52119530	NM_015946	53918	5q11.2	Hs.644352 Hs.669791	9	endonuclease activity protein binding nucleus cytoplasm translation cell cycle cell proliferation hydrolase activity metal ion binding chromosome organization cell division
220547_s_at	-0.455	7.160	-3.138	6.670e-03	0.189	-2.313	FAM35A	family with sequence similarity 35, member A	10	88844932	NM_019054	54537	10q23.2	Hs.500419	6
234937_x_at	0.462	4.384	3.138	6.673e-03	0.189	-2.313	ZFP28	zinc finger protein 28 homolog (mouse)	19	61742128	AC007228	140612		Hs.14794	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222558_at	-0.561	5.536	-3.138	6.675e-03	0.189	-2.314	RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	18	-31823789	T79568	55197	18q12.2	Hs.464912	3
219377_at	-0.498	6.182	-3.137	6.690e-03	0.190	-2.316	FAM59A	family with sequence similarity 59, member A	18	-28101474	NM_022751	64762	18q12.1	Hs.444314	7
240486_at	0.285	4.261	3.137	6.697e-03	0.190	-2.317	HELZ	helicase with zinc finger	17	-62497015	AA761673	9931	17q24.2	Hs.370140 Hs.569824 Hs.596366	8	nucleotide binding nucleic acid binding helicase activity ATP binding nucleus zinc ion binding hydrolase activity metal ion binding
229405_at	0.426	5.161	3.135	6.714e-03	0.190	-2.319	KIF7	kinesin family member 7	15	-87972204	BF515033	374654	15q26.1	Hs.513134	5	nucleotide binding microtubule motor activity ATP binding microtubule-based movement
200685_at	-0.402	7.117	-3.135	6.714e-03	0.190	-2.319	SFRS11	splicing factor, arginine/serine-rich 11	1	70443952	AU146237	9295	1p31	Hs.479693	13	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleolus RNA splicing
227705_at	1.214	5.007	3.135	6.715e-03	0.190	-2.319	TCEAL7	transcription elongation factor A (SII)-like 7	X	102471820	BF591534	56849	Xq22.1	Hs.21861	7	nucleus regulation of transcription
213597_s_at	0.279	2.947	3.135	6.715e-03	0.190	-2.319	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF002474	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
1561281_a_at	0.353	3.189	3.135	6.716e-03	0.190	-2.319	LOC284576	hypothetical protein LOC284576	1		AK090497	284576	1q32.1	Hs.585440	1
221430_s_at	-0.704	6.086	-3.135	6.719e-03	0.190	-2.320	RNF146	ring finger protein 146	6	127629712	NM_030963	81847	6q22.1-q22.33	Hs.267120	12	protein binding zinc ion binding metal ion binding
210298_x_at	-0.870	11.878	-3.135	6.724e-03	0.190	-2.320	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF098518	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
224336_s_at	-0.475	5.069	-3.134	6.728e-03	0.190	-2.321	DUSP16	dual specificity phosphatase 16	12	-12520097	AB052156	80824	12p13	Hs.536535	12	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive	MAPK signaling pathway
220510_at	0.381	6.815	3.133	6.743e-03	0.190	-2.323	RHBG	Rh family, B glycoprotein (gene/pseudogene)	1	154605626	NM_020407	57127	1q21.3	Hs.131835	16	plasma membrane integral to plasma membrane transport ammonium transmembrane transporter activity spectrin-associated cytoskeleton basolateral plasma membrane basolateral plasma membrane ankyrin binding cytoplasmic vesicle anchored to plasma membrane ammonia transporter activity ammonia transporter activity transepithelial ammonium transport
209785_s_at	-0.684	9.028	-3.133	6.745e-03	0.190	-2.323	PLA2G4C	phospholipase A2, group IVC (cytosolic, calcium-independent)	19	-53242912	AF065214	8605	19q13.3	Hs.631562	22	phospholipid binding cytosol inflammatory response intracellular signaling cascade parturition metabolic process membrane lipid catabolic process hydrolase activity arachidonic acid metabolic process glycerophospholipid catabolic process calcium-independent phospholipase A2 activity
209863_s_at	-0.752	6.267	-3.133	6.748e-03	0.190	-2.323	TP63	tumor protein p63	3	190831909, 190831909, 190990142, 190990142	AF091627	8626	3q28	Hs.137569	238	response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization
212791_at	-0.404	6.242	-3.132	6.761e-03	0.190	-2.325	C1orf216	chromosome 1 open reading frame 216	1	-35952063	AL042729	127703	1p34.3	Hs.112023	3
228024_at	-0.511	6.593	-3.130	6.785e-03	0.190	-2.329	VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)	8	17148771	AW028100	137492	8p22	Hs.343873 Hs.512464	8	nucleus endosome protein transport membrane	Endocytosis
222916_s_at	-0.476	5.661	-3.130	6.790e-03	0.190	-2.329	HDLBP	high density lipoprotein binding protein	2	-241815351, -241815351	AF116718	3069	2q37.3	Hs.471851	25	RNA binding protein binding nucleus cytoplasm plasma membrane lipid metabolic process lipid transport steroid metabolic process cholesterol metabolic process lipid binding high-density lipoprotein particle
213726_x_at	-0.739	8.850	-3.130	6.790e-03	0.190	-2.329	TUBB2C	tubulin, beta 2C	9	139255531	AA515698	10383	9q34	Hs.433615	25	nucleotide binding GTPase activity structural molecule activity GTP binding cytoskeleton microtubule cell motion microtubule-based movement natural killer cell mediated cytotoxicity MHC class I protein binding protein complex unfolded protein binding protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
210540_s_at	-0.656	3.874	-3.130	6.790e-03	0.190	-2.329	B4GALT4	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	3	-120413278	BC004523	8702	3q13.3	Hs.13225	14	N-acetyllactosamine synthase activity Golgi apparatus carbohydrate metabolic process membrane lipid metabolic process galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding metal ion binding	Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
224694_at	-0.857	7.193	-3.129	6.799e-03	0.190	-2.330	ANTXR1	anthrax toxin receptor 1	2	69093779, 69093779, 69093779	AF279145	84168	2p13.1	Hs.165859	24	transmembrane receptor activity collagen binding membrane integral to membrane lamellipodium membrane filopodium membrane actin cytoskeleton reorganization substrate adhesion-dependent cell spreading metal ion binding actin filament binding
1558315_s_at	-0.523	3.268	-3.129	6.804e-03	0.190	-2.331	HOOK3	hook homolog 3 (Drosophila)	8	42871189	AV710762	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
209089_at	-0.375	9.034	-3.128	6.808e-03	0.190	-2.332	RAB5A	RAB5A, member RAS oncogene family	3	19963575	BC001267	5868	3p24-p22	Hs.475663	73	nucleotide binding ruffle GTPase activity protein binding protein binding GTP binding early endosome plasma membrane endocytosis small GTPase mediated signal transduction protein transport guanyl nucleotide binding endocytic vesicle melanosome membrane raft	Endocytosis Amyotrophic lateral sclerosis (ALS)
203013_at	-0.372	6.639	-3.128	6.808e-03	0.190	-2.332	ECD	ecdysoneless homolog (Drosophila)	10	-74564288	NM_007265	11319	10q22.1-q22.2	Hs.631822	11	transcription coactivator activity nucleus cytoplasm regulation of glycolysis transcription from RNA polymerase II promoter regulation of transcription
201705_at	-0.429	9.932	-3.128	6.810e-03	0.190	-2.332	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	16	72888181	NM_002811	5713	16q23-q24	Hs.440604	47	proteasome complex protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
209031_at	0.959	6.696	3.128	6.816e-03	0.191	-2.333	CADM1	cell adhesion molecule 1	11	-114549554	AL519710	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
212403_at	-0.514	7.503	-3.127	6.828e-03	0.191	-2.334	UBE3B	ubiquitin protein ligase E3B	12	108399821	AI749193	89910	12q24.11	Hs.374067	8	intracellular protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
226617_at	-0.722	8.348	-3.126	6.837e-03	0.191	-2.336	ARL5A	ADP-ribosylation factor-like 5A	2	-152365725	AW291264	26225	2q23.3	Hs.470233	6	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
200723_s_at	-0.433	8.059	-3.126	6.839e-03	0.191	-2.336	CAPRIN1	cell cycle associated protein 1	11	34029805, 34029805	NM_005898	4076	11p13	Hs.471818	10	protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection
223187_s_at	-0.328	7.516	-3.126	6.845e-03	0.191	-2.337	ORMDL1	ORM1-like 1 (S. cerevisiae)	2	-190343237	BC005200	94101	2q32	Hs.709387	7	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane
242919_at	0.608	5.598	3.126	6.848e-03	0.191	-2.337	ZNF253	zinc finger protein 253	19	19837713	AV683221	56242	19p13.11	Hs.659321	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity metal ion binding
209214_s_at	-0.360	8.040	-3.125	6.860e-03	0.191	-2.339	EWSR1	Ewing sarcoma breakpoint region 1	22	27993997, 27993997	BC004817	2130	22q12.2	Hs.374477	90	nucleotide binding RNA binding calmodulin binding intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding
227031_at	-0.557	7.445	-3.125	6.861e-03	0.191	-2.339	SNX13	sorting nexin 13	7	-17796910	AV681975	23161	7p21.1	Hs.487648	10	signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding
207154_at	0.386	6.219	3.124	6.876e-03	0.191	-2.341	DIO3	deiodinase, iodothyronine, type III	14	101097440	NM_001362	1735	14q32	Hs.49322	19	thyroxine 5'-deiodinase activity cellular_component endosome plasma membrane biological_process selenium binding integral to membrane thyroxine 5-deiodinase activity positive regulation of multicellular organism growth thyroid hormone catabolic process hormone biosynthetic process oxidation reduction
226439_s_at	0.724	5.936	3.123	6.881e-03	0.191	-2.341	NBEA	neurobeachin	13	34414455	AI246710	26960	13q13	Hs.491172	11	protein binding cytoplasm trans-Golgi network cytosol plasma membrane protein localization endomembrane system protein kinase binding
235093_at	-0.475	7.225	-3.123	6.881e-03	0.191	-2.341	PEX13	peroxisomal biogenesis factor 13	2	61098315	BE564430	5194	2p14-p16	Hs.161377	21	fatty acid alpha-oxidation neuron migration suckling behavior protein binding membrane fraction peroxisome peroxisomal membrane integral to peroxisomal membrane locomotory behavior protein transport membrane integral to membrane protein import into peroxisome matrix, docking protein import into peroxisome matrix, docking cerebral cortex cell migration microtubule-based peroxisome localization
211969_at	-0.440	11.215	-3.123	6.892e-03	0.191	-2.343	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	BG420237	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
210954_s_at	-0.455	4.063	-3.122	6.895e-03	0.191	-2.343	TSC22D2	TSC22 domain family, member 2	3	151609477	AF201292	9819	3q25.1	Hs.665220 Hs.715600	5	transcription factor activity regulation of transcription, DNA-dependent
216100_s_at	-1.102	4.756	-3.121	6.909e-03	0.191	-2.345	TOR1AIP1	torsin A interacting protein 1	1	178118042	BG289527	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
1558487_a_at	0.493	7.829	3.121	6.911e-03	0.191	-2.345	TMED4	transmembrane emp24 protein transport domain containing 4	7	-44585286	AK074557	222068	7p13	Hs.598832 Hs.715273	11	endoplasmic reticulum transport membrane integral to membrane
205029_s_at	-1.917	4.768	-3.121	6.918e-03	0.191	-2.346	FABP7	fatty acid binding protein 7, brain	6	123142344	NM_001446	2173	6q22-q23	Hs.26770	28	transporter activity cytoplasm transport nervous system development negative regulation of cell proliferation lipid binding	PPAR signaling pathway
210638_s_at	-0.337	8.833	-3.121	6.919e-03	0.191	-2.346	FBXO9	F-box protein 9	6	53037754, 53038215, 53043729	AF176704	26268	6p12.3-p11.2	Hs.216653	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein ubiquitination modification-dependent protein catabolic process
220248_x_at	-0.342	9.150	-3.120	6.923e-03	0.191	-2.347	NSFL1C	NSFL1 (p97) cofactor (p47)	20	-1370810	NM_018839	55968	20p13	Hs.12865	20	protein binding nucleus Golgi apparatus Golgi stack lipid binding
209695_at	0.642	9.858	3.120	6.924e-03	0.191	-2.347	PTP4A3	protein tyrosine phosphatase type IVA, member 3	8	142501188	BC003105	11156	8q24.3	Hs.43666	45	prenylated protein tyrosine phosphatase activity early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity identical protein binding
213868_s_at	-0.602	4.712	-3.120	6.928e-03	0.191	-2.347	DHRS7	dehydrogenase/reductase (SDR family) member 7	14	-59681251	AW243128	51635	14q23.1	Hs.59719	7	binding oxidoreductase activity oxidation reduction
200064_at	-0.379	10.780	-3.119	6.944e-03	0.192	-2.350	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	6	44322826	AF275719	3326	6p12	Hs.509736 Hs.689683 Hs.701787	50	nucleotide binding ATP binding cytoplasm protein folding response to unfolded protein nitric-oxide synthase regulator activity TPR domain binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process melanosome positive regulation of nitric oxide biosynthetic process unfolded protein binding regulation of interferon-gamma-mediated signaling pathway regulation of type I interferon-mediated signaling pathway	Antigen processing and presentation Pathways in cancer Prostate cancer
220944_at	0.347	5.810	3.118	6.956e-03	0.192	-2.351	PGLYRP4	peptidoglycan recognition protein 4	1	-151569220	NM_020393	57115	1q21	Hs.58356	5	protein binding intracellular N-acetylmuramoyl-L-alanine amidase activity peptidoglycan catabolic process peptidoglycan receptor activity membrane detection of bacterium innate immune response defense response to Gram-positive bacterium
203315_at	-0.410	8.167	-3.118	6.957e-03	0.192	-2.351	NCK2	NCK adaptor protein 2	2	105727785, 105834736	BC000103	8440	2q12	Hs.529244 Hs.707062	34	protein binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal transduction signal complex assembly epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor activity cytoskeletal adaptor activity negative regulation of cell proliferation vesicle membrane cell migration lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
214975_s_at	-0.527	3.866	-3.117	6.967e-03	0.192	-2.353	MTMR1	myotubularin related protein 1	X	149612526	AK001816	8776	Xq28	Hs.347187	10	protein tyrosine phosphatase activity cellular_component plasma membrane dephosphorylation hydrolase activity phosphatase activity	Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways
1557073_s_at	-0.540	5.441	-3.117	6.974e-03	0.192	-2.354	TTBK2	tau tubulin kinase 2	15	-40823835	AK074481	146057	15q15.2	Hs.659846 Hs.713940	12	nucleotide binding protein serine/threonine kinase activity ATP binding cell death transferase activity peptidyl-serine phosphorylation
223165_s_at	-0.883	6.905	-3.116	6.992e-03	0.192	-2.356	IP6K2	inositol hexakisphosphate kinase 2	3	-48705886, -48700439	BC004469	51447	3p21.31	Hs.595983	18	nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding nucleus cytoskeleton inositol trisphosphate 3-kinase activity transferase activity negative regulation of cell growth positive regulation of apoptosis phosphoinositide phosphorylation
201823_s_at	-0.785	6.396	-3.115	6.997e-03	0.192	-2.357	RNF14	ring finger protein 14	5	141326620, 141328805, 141328916	NM_004290	9604	5q23.3-q31.1	Hs.483616	19	transcription coactivator activity transcription coactivator activity protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter signal transduction zinc ion binding protein ubiquitination ligase activity small conjugating protein ligase activity modification-dependent protein catabolic process androgen receptor signaling pathway response to estradiol stimulus regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding
204856_at	0.328	5.748	3.115	7.000e-03	0.192	-2.357	B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	19	17766918	NM_014256	10331	19p13.1	Hs.657825 Hs.69009	13	Golgi apparatus integral to plasma membrane protein amino acid glycosylation galactosyltransferase activity membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
218401_s_at	-0.719	6.409	-3.114	7.015e-03	0.193	-2.359	ZNF281	zinc finger protein 281	1	-198642042	NM_012482	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
233523_at	0.392	4.436	3.114	7.021e-03	0.193	-2.360	C20orf186	chromosome 20 open reading frame 186	20	31132978	AL121756	149954	20q11.21	Hs.38961	4	extracellular region cytoplasm lipid binding
210458_s_at	-0.953	4.705	-3.113	7.029e-03	0.193	-2.361	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	BC003388	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
1565389_s_at	0.282	5.042	3.113	7.030e-03	0.193	-2.361	GRM5	glutamate receptor, metabotropic 5	11	-87877392, -87877392	S64316	2915	11q14.2-q14.3	Hs.147361 Hs.680431 Hs.719168	33	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway synaptic transmission glutamate receptor activity	Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction Long-term potentiation Long-term depression Huntington's disease
221926_s_at	0.444	5.445	3.113	7.030e-03	0.193	-2.361	IL17RC	interleukin 17 receptor C	3	9933763	BF196320	84818	3p25.3 3p25.3-p24.1	Hs.129959	14	receptor activity plasma membrane integral to membrane
223289_s_at	-1.230	7.232	-3.112	7.040e-03	0.193	-2.362	USP38	ubiquitin specific peptidase 38	4	144325519	AF211481	84640		Hs.480848	7	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
35436_at	-0.344	7.607	-3.112	7.040e-03	0.193	-2.362	GOLGA2	golgi autoantigen, golgin subfamily a, 2	9	-130057928	L06147	2801	9q34.11	Hs.155827	45	protein binding Golgi apparatus membrane
52285_f_at	-0.805	3.813	-3.112	7.043e-03	0.193	-2.363	CEP76	centrosomal protein 76kDa	18	-12662630	AW002970	79959	18p11.21	Hs.236940	7	protein binding centriole regulation of centriole replication
203742_s_at	-0.466	5.727	-3.111	7.060e-03	0.193	-2.365	TDG	thymine-DNA glycosylase	12	102883722	BF674842	6996	12q24.1	Hs.584809	47	damaged DNA binding protein binding nucleus nucleoplasm nucleoplasm base-excision repair mismatch repair response to DNA damage stimulus metabolic process pyrimidine-specific mismatch base pair DNA N-glycosylase activity DNA N-glycosylase activity mismatched DNA binding depyrimidination	Base excision repair
204537_s_at	0.346	4.456	3.110	7.070e-03	0.193	-2.366	GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	X	-150872251	NM_004961	2564	Xq28	Hs.22785	17	GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport gamma-aminobutyric acid signaling pathway cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
200862_at	-1.169	7.125	-3.110	7.077e-03	0.193	-2.367	DHCR24	24-dehydrocholesterol reductase	1	-55087887	NM_014762	1718	1p33-p31.1	Hs.498727	25	nucleus endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus cholesterol biosynthetic process cholesterol biosynthetic process apoptosis anti-apoptosis response to oxidative stress cell cycle arrest protein localization tissue development membrane integral to membrane membrane organization oxidoreductase activity enzyme binding male genitalia development plasminogen activation peptide antigen binding amyloid precursor protein catabolic process negative regulation of caspase activity neuroprotection skin development delta24-sterol reductase activity FAD binding oxidation reduction	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
204813_at	0.521	5.818	3.109	7.084e-03	0.193	-2.368	MAPK10	mitogen-activated protein kinase 10	4	-87156655, -87156655, -87156655, -87156655	NM_002753	5602	4q22.1-q23	Hs.125503	54	nucleotide binding protein serine/threonine kinase activity JUN kinase activity MAP kinase activity MAP kinase kinase activity ATP binding cytoplasm protein amino acid phosphorylation signal transduction JNK cascade transferase activity	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Pancreatic cancer
213421_x_at	0.359	5.154	3.109	7.088e-03	0.193	-2.368	PRSS3	protease, serine, 3	9	33740514, 33785558	AW007273	5646	9p11.2	Hs.654513	22	serine-type endopeptidase activity calcium ion binding protein binding extracellular region extracellular space proteolysis proteolysis digestion peptidase activity zymogen activation endothelial cell migration	Neuroactive ligand-receptor interaction
201122_x_at	-0.676	9.062	-3.109	7.092e-03	0.193	-2.369	EIF5A	eukaryotic translation initiation factor 5A	17	7151041, 7151579, 7152011, 7152417	BC000751	1984	17p13-p12	Hs.534314	52	RNA binding translation initiation factor activity translation elongation factor activity nucleus annulate lamellae nuclear pore cytoplasm endoplasmic reticulum cytosol mRNA export from nucleus translation translational frameshifting protein export from nucleus nucleocytoplasmic transport nucleocytoplasmic transport induction of apoptosis cell proliferation peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine protein transport membrane U6 snRNA binding viral genome replication ribosome binding positive regulation of translational elongation positive regulation of translational termination positive regulation of translational initiation protein N-terminus binding intracellular protein transmembrane transport
226445_s_at	-0.335	7.086	-3.108	7.098e-03	0.193	-2.370	TRIM41	tripartite motif-containing 41	5	180582911	AI743109	90933	5q35.3	Hs.441488	9	protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding
230115_at	-0.513	6.442	-3.108	7.101e-03	0.193	-2.370	DKFZp779M0652	hypothetical DKFZp779M0652	11	45749558	BE348376	374387	11p11.2	Hs.632142	1
224695_at	-0.449	7.231	-3.108	7.102e-03	0.193	-2.370	C2orf29	chromosome 2 open reading frame 29	2	101235776	AK024221	55571	2q11.2	Hs.715598	5	molecular_function cellular_component cell proliferation
203884_s_at	-0.314	6.039	-3.108	7.106e-03	0.193	-2.371	RAB11FIP2	RAB11 family interacting protein 2 (class I)	10	-119754418	NM_014904	22841	10q26.11	Hs.173656	20	protein binding endosome plasma membrane protein transport	Endocytosis
1567458_s_at	-0.894	7.595	-3.107	7.110e-03	0.193	-2.371	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	AJ012502	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
205750_at	0.582	7.099	3.107	7.122e-03	0.193	-2.373	BPHL	biphenyl hydrolase-like (serine hydrolase)	6	3063924	NM_004332	670	6p25	Hs.10136	12	mitochondrion cellular amino acid and derivative metabolic process response to toxin hydrolase activity
227687_at	-0.598	5.901	-3.106	7.131e-03	0.193	-2.374	HYLS1	hydrolethalus syndrome 1	11	125258718, 125262164	AL523264	219844	11q24.2	Hs.585071	7	cytoplasm
228427_at	0.816	4.468	3.104	7.162e-03	0.194	-2.378	FBXO16	F-box protein 16	8	-28341847	BF196856	157574	8p21.1	Hs.659190	5	modification-dependent protein catabolic process
218031_s_at	-0.639	8.265	-3.102	7.184e-03	0.194	-2.381	FOXN3	forkhead box N3	14	-88692268, -88692268	NM_018589	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
226500_at	-0.310	8.750	-3.102	7.188e-03	0.194	-2.381	ZBTB47	zinc finger and BTB domain containing 47	3	42675877	AI806872	92999	3p22.1	Hs.409561	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
207980_s_at	-1.441	4.817	-3.101	7.197e-03	0.195	-2.382	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	6	-139735089	NM_006079	10370	6q23.3	Hs.82071	21	negative regulation of transcription from RNA polymerase II promoter nuclear chromatin response to hypoxia liver development transcription factor activity transcription coactivator activity transcription corepressor activity protein binding nucleus anti-apoptosis determination of left/right symmetry heart development heart development positive regulation of specific transcription from RNA polymerase II promoter positive regulation of cell-cell adhesion negative regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway response to fluid shear stress positive regulation of cell cycle positive regulation of transcription, DNA-dependent
230656_s_at	-0.479	7.196	-3.101	7.202e-03	0.195	-2.383	CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)	16	67723999	AL578336	84916	16q22.1	Hs.461113	13	molecular_function nucleus nucleolus biological_process
202955_s_at	-0.454	5.915	-3.099	7.236e-03	0.195	-2.387	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	8	-68272450	AF084520	10565	8q13	Hs.656902	22	ARF guanyl-nucleotide exchange factor activity binding intracellular exocytosis ARF GTPase activator activity myosin binding regulation of ARF protein signal transduction
218501_at	0.520	6.685	3.099	7.238e-03	0.195	-2.387	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	3	-56736485, -56736485, -56736485	NM_019555	50650	3p21-p13	Hs.476402	15	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction
219452_at	0.320	4.806	3.098	7.243e-03	0.195	-2.388	DPEP2	dipeptidase 2	16	-66578795	NM_022355	64174	16q22.1	Hs.372633	7	proteolysis peptidase activity metalloexopeptidase activity dipeptidyl-peptidase activity zinc ion binding membrane dipeptidase activity anchored to membrane metal ion binding
201674_s_at	0.543	10.078	3.098	7.248e-03	0.195	-2.389	AKAP1	A kinase (PRKA) anchor protein 1	17	52517551	BC000729	8165	17q21-q23	Hs.463506	27	RNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane membrane integral to membrane
205079_s_at	-0.449	7.872	-3.098	7.255e-03	0.195	-2.390	MPDZ	multiple PDZ domain protein	9	-13095702	NM_003829	8777	9p24-p22	Hs.169378	25	protein binding plasma membrane tight junction postsynaptic density synaptosome cell junction dendrite cell projection interspecies interaction between organisms synapse postsynaptic membrane	Tight junction
209206_at	-0.468	7.696	-3.098	7.255e-03	0.195	-2.390	SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae)	1	143807763	AV701283	9554	1q21.1	Hs.632438 Hs.715002	13	protein binding endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus ER to Golgi vesicle-mediated transport protein transport membrane integral to membrane vesicle-mediated transport melanosome	SNARE interactions in vesicular transport
212202_s_at	-0.491	7.231	-3.097	7.258e-03	0.195	-2.390	TMEM87A	transmembrane protein 87A	15	-40337427, -40290017	BG493972	25963	15q15.1	Hs.511138 Hs.719196	6	membrane integral to membrane
211769_x_at	-0.738	7.546	-3.097	7.259e-03	0.195	-2.390	SERINC3	serine incorporator 3	20	-42561314, -42558277	BC006088	10955	20q13.1-q13.3	Hs.272168 Hs.696043	10	protein binding Golgi apparatus plasma membrane induction of apoptosis integral to membrane
219299_at	-0.517	6.364	-3.097	7.267e-03	0.195	-2.391	TRMT12	tRNA methyltransferase 12 homolog (S. cerevisiae)	8	125532228	NM_017956	55039	8q24.13	Hs.9925	9	tRNA processing methyltransferase activity transferase activity
226582_at	0.545	5.377	3.096	7.276e-03	0.195	-2.392	LOC400043	hypothetical LOC400043	12	52806121	AL520272	400043	12q13.13	Hs.19193	2
202122_s_at	-0.473	8.268	-3.095	7.287e-03	0.196	-2.394	PLIN3	perilipin 3	19	-4789345	NM_005817	10226	19p13.3	Hs.140452	35	protein binding cytoplasm endosome Golgi apparatus lipid particle membrane vesicle-mediated transport
214948_s_at	-0.544	6.648	-3.095	7.291e-03	0.196	-2.394	TMF1	TATA element modulatory factor 1	3	-69151667	AL050136	7110	3p21-p12	Hs.267632	15	Golgi membrane DNA binding RNA polymerase II transcription factor activity transcription cofactor activity protein binding nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter membrane
1554334_a_at	-1.102	8.170	-3.095	7.293e-03	0.196	-2.394	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	15	76343541, 76344043, 76345614	BC031044	55466	15q25.1	Hs.513053	5	protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding
243508_at	-0.376	4.338	-3.095	7.295e-03	0.196	-2.394	C20orf196	chromosome 20 open reading frame 196	20	5679042	AV715251	149840	20p12.3	Hs.529340	1
211950_at	-0.391	8.097	-3.094	7.306e-03	0.196	-2.396	UBR4	ubiquitin protein ligase E3 component n-recognin 4	1	-19273586	AB007931	23352	1p36.13	Hs.148078 Hs.649405	11	ubiquitin-protein ligase activity calmodulin binding nucleus cytoplasm cytoskeleton zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process interspecies interaction between organisms metal ion binding
200928_s_at	-0.334	3.394	-3.094	7.315e-03	0.196	-2.397	RAB14	RAB14, member RAS oncogene family	9	-122980236	AL162081	51552	9q32-q34.11	Hs.371563 Hs.713585	19	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm
219069_at	-0.629	6.249	-3.093	7.327e-03	0.196	-2.398	ANKRD49	ankyrin repeat domain 49	11	93866800	NM_017704	54851	11q21	Hs.29052	5
207615_s_at	0.329	4.221	3.093	7.331e-03	0.196	-2.399	C16orf3	chromosome 16 open reading frame 3	16	-88622816	NM_001214	750	16q24.3	Hs.633032	3	molecular_function cellular_component biological_process
226750_at	-0.683	6.597	-3.092	7.333e-03	0.196	-2.399	LARP1B	La ribonucleoprotein domain family, member 1B	4	129201952, 129201952, 129201952	AI767732	55132	4q28.2	Hs.657067	3	RNA binding
210330_at	-0.553	4.597	-3.092	7.337e-03	0.196	-2.400	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	5	155686344, 155686344	U58331	6444	5q33-q34	Hs.387207 Hs.644733	29	protein binding cytoplasm cytoskeleton plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex integral to membrane	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
234876_at	0.339	5.107	3.092	7.341e-03	0.196	-2.400	COX6A1	cytochrome c oxidase subunit VIa polypeptide 1	12	119360286	U82486	1337	12q24.2	Hs.497118	11	cytochrome-c oxidase activity mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex IV generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
215509_s_at	0.292	3.692	3.090	7.372e-03	0.197	-2.404	BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	2	-111111882	AL137654	699	2q14	Hs.469649	55	nucleotide binding condensed chromosome kinetochore condensed nuclear chromosome, centromeric region protein serine/threonine kinase activity ATP binding nucleus spindle pole body protein amino acid phosphorylation cell cycle mitosis mitotic cell cycle spindle assembly checkpoint cell proliferation transferase activity cell division	Cell cycle
204844_at	0.790	5.317	3.090	7.373e-03	0.197	-2.404	ENPEP	glutamyl aminopeptidase (aminopeptidase A)	4	111616677	L12468	2028	4q25	Hs.435765	25	angiogenesis aminopeptidase activity calcium ion binding plasma membrane integral to plasma membrane brush border proteolysis cell-cell signaling peptidase activity metalloexopeptidase activity zinc ion binding cell proliferation external side of plasma membrane apical plasma membrane cell migration cytoplasmic vesicle	Renin-angiotensin system
205369_x_at	-0.536	4.935	-3.089	7.378e-03	0.197	-2.405	DBT	dihydrolipoamide branched chain transacylase E2	1	-100425065	J03208	1629	1p31	Hs.709187	34	protein binding mitochondrion mitochondrial alpha-ketoglutarate dehydrogenase complex metabolic process acyltransferase activity transferase activity lipoic acid binding mitochondrial nucleoid dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity acyl-CoA biosynthetic process cofactor binding	Valine, leucine and isoleucine degradation Metabolic pathways
229177_at	0.387	5.551	3.089	7.390e-03	0.197	-2.406	C16orf89	chromosome 16 open reading frame 89	16	-5034123	AI823572	146556	16p13.3	Hs.11782	4	extracellular region
217730_at	-0.491	8.118	-3.088	7.395e-03	0.197	-2.407	TMBIM1	transmembrane BAX inhibitor motif containing 1	2	-218847160	NM_022152	64114	2p24.3-p24.1	Hs.591605	9	membrane integral to membrane
212350_at	-0.912	7.557	-3.088	7.399e-03	0.197	-2.407	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	AB029031	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
220028_at	0.394	5.958	3.088	7.404e-03	0.197	-2.408	ACVR2B	activin A receptor, type IIB	3	38470793	NM_001106	93	3p22	Hs.174273	38	nucleotide binding magnesium ion binding receptor activity ATP binding cytoplasm plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction anterior/posterior pattern formation cell surface activin receptor activity, type II transferase activity growth factor binding manganese ion binding positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of osteoblast differentiation	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
222653_at	-0.406	6.777	-3.087	7.408e-03	0.197	-2.409	PNPO	pyridoxamine 5'-phosphate oxidase	17	43373887	AA005137	55163	17q21.32	Hs.631742	13	pyridoxamine-phosphate oxidase activity pyridoxine biosynthetic process FMN binding oxidoreductase activity, acting on the CH-NH2 group of donors oxidation reduction	Vitamin B6 metabolism Metabolic pathways
1561687_a_at	0.526	2.935	3.087	7.409e-03	0.197	-2.409	ZNF382	zinc finger protein 382	19	41788060	BC038358	84911	19q13.12	Hs.631591	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
205603_s_at	-1.069	6.759	-3.087	7.421e-03	0.197	-2.410	DIAPH2	diaphanous homolog 2 (Drosophila)	X	95826317, 95826317	NM_007309	1730	Xq21.33	Hs.226483 Hs.716101	14	cytokinesis actin binding receptor binding cytoplasm early endosome Golgi apparatus cytosol multicellular organismal development cellular component organization Rho GTPase binding actin cytoskeleton organization cell differentiation oogenesis	Regulation of actin cytoskeleton
212018_s_at	-0.618	8.731	-3.086	7.435e-03	0.197	-2.412	RSL1D1	ribosomal L1 domain containing 1	16	-11835555	AK000822	26156	16p13.13	Hs.401842	17	RNA binding structural constituent of ribosome protein binding intracellular nucleus nucleolus ribosome RNA processing translation regulation of protein localization
232175_at	0.356	6.270	3.085	7.445e-03	0.198	-2.413	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AI972094	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
209286_at	-1.139	6.516	-3.084	7.453e-03	0.198	-2.414	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	2	-37724246	AI754416	10602	2p21	Hs.369574	17	protein binding cytoskeletal regulatory protein binding cytoplasm signal transduction regulation of cell shape actin cytoskeleton membrane
225381_at	0.761	5.988	3.083	7.480e-03	0.198	-2.417	LOC399959	hypothetical LOC399959	11	-121465022	AW162210	399959	11q24.1	Hs.44098	2
1554464_a_at	-0.881	5.317	-3.083	7.481e-03	0.198	-2.417	CRTAP	cartilage associated protein	3	33130453	BC008745	10491	3p22.3	Hs.719160	10	extracellular region proteinaceous extracellular matrix
219016_at	-0.381	7.179	-3.083	7.481e-03	0.198	-2.417	FASTKD5	FAST kinase domains 5	20	-3075164	NM_021826	60493	20p13	Hs.654646	4	protein kinase activity ATP binding apoptosis
229500_at	-0.564	4.475	-3.083	7.483e-03	0.198	-2.418	SLC30A9	solute carrier family 30 (zinc transporter), member 9	4	41687279	AI609256	10463	4p13-p12	Hs.479634	6	nucleotide binding transcription factor activity nucleus cytoskeleton cation transport zinc ion transport biological_process zinc ion binding cation transmembrane transporter activity membrane integral to membrane regulation of transcription
212004_at	-0.285	7.617	-3.081	7.501e-03	0.198	-2.420	C1orf144	chromosome 1 open reading frame 144	1	16566169	AL050028	26099	1p36.13	Hs.252967	2
212397_at	-0.521	9.676	-3.081	7.504e-03	0.198	-2.420	RDX	radixin	11	-109605375	AL137751	5962	11q23	Hs.263671 Hs.592679	46	ruffle actin binding cytoplasm cytoskeleton plasma membrane extrinsic to membrane lamellipodium microvillus assembly filopodium stereocilium apical protein localization apical part of cell actin filament capping	Regulation of actin cytoskeleton
228601_at	0.411	4.627	3.081	7.505e-03	0.198	-2.420	LOC401022	hypothetical LOC401022	2		AW340112	401022	2q31.2	Hs.98661	1
38269_at	0.309	6.172	3.081	7.506e-03	0.198	-2.420	PRKD2	protein kinase D2	19	-51869412, -51869412	AL050147	25865	19q13.3	Hs.466987	25	nucleotide binding protein kinase C activity ATP binding intracellular protein amino acid phosphorylation intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding metal ion binding
233587_s_at	0.730	5.782	3.081	7.509e-03	0.198	-2.421	SIPA1L2	signal-induced proliferation-associated 1 like 2	1	-230600334	AK022852	57568	1q42.2	Hs.715656	8	GTPase activator activity protein binding intracellular regulation of small GTPase mediated signal transduction
221472_at	-0.359	8.414	-3.079	7.534e-03	0.199	-2.424	SERINC3	serine incorporator 3	20	-42561314, -42558277	Z97053	10955	20q13.1-q13.3	Hs.272168 Hs.696043	10	protein binding Golgi apparatus plasma membrane induction of apoptosis integral to membrane
222885_at	0.441	8.351	3.079	7.539e-03	0.199	-2.424	EMCN	endomucin	4	-101535522	AF205940	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
219959_at	1.237	5.116	3.079	7.542e-03	0.199	-2.425	MOCOS	molybdenum cofactor sulfurase	18	32021477	NM_017947	55034	18q12	Hs.405028	10	cellular_component Mo-molybdopterin cofactor biosynthetic process metabolic process Mo-molybdopterin cofactor sulfurase activity lyase activity molybdenum ion binding pyridoxal phosphate binding molybdopterin cofactor metabolic process
215119_at	1.372	5.238	3.078	7.550e-03	0.199	-2.426	MYO16	myosin XVI	13	108046500	AI522028	23026	13q33.3	Hs.656587	7	nucleotide binding motor activity ATP binding nucleoplasm cytoplasm plasma membrane negative regulation of cell proliferation myosin complex cerebellum development negative regulation of S phase of mitotic cell cycle perinuclear region of cytoplasm actin filament binding
208042_at	-0.478	4.909	-3.078	7.558e-03	0.199	-2.427	AGGF1	angiogenic factor with G patch and FHA domains 1	5	76361987	NM_013303	55109	5q13.3	Hs.634849	12	vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm
203581_at	-0.433	8.186	-3.077	7.566e-03	0.199	-2.428	RAB4A	RAB4A, member RAS oncogene family	1	227473501	BC002438	5867	1q42-q43	Hs.296169	43	nucleotide binding GTPase activity GTP binding cytoplasm small GTPase mediated signal transduction protein transport membrane	Endocytosis
210672_s_at	-0.376	6.099	-3.077	7.574e-03	0.199	-2.429	C16orf35	chromosome 16 open reading frame 35	16	-75803, -75803	BC004185	8131	16p13.3	Hs.19699	6	molecular_function cellular_component biological_process
215910_s_at	0.309	3.823	3.075	7.591e-03	0.199	-2.431	FNDC3A	fibronectin type III domain containing 3A	13	48448048, 48582449	AL137000	22862	13q14.2	Hs.508010	10	acrosomal vesicle Golgi apparatus cytosol spermatid development fertilization vesicle membrane cell-cell adhesion cytoplasmic vesicle vesicular fraction Sertoli cell development
201723_s_at	-0.610	8.049	-3.075	7.592e-03	0.199	-2.431	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	U41514	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
223654_s_at	0.297	4.903	3.075	7.593e-03	0.199	-2.431	BRUNOL4	bruno-like 4, RNA binding protein (Drosophila)	18	-33077005	BC004167	56853	18q12	Hs.435976 Hs.600908	12	nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome translation repressor activity, nucleic acid binding nucleus cytoplasm germ cell development embryonic development BRE binding
201647_s_at	-0.627	5.963	-3.075	7.597e-03	0.199	-2.431	SCARB2	scavenger receptor class B, member 2	4	-77298917	NM_005506	950	4q21.1	Hs.349656 Hs.714206	24	receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane	Lysosome
200711_s_at	-0.535	9.463	-3.075	7.598e-03	0.199	-2.432	SKP1	S-phase kinase-associated protein 1	5	-133519980	NM_003197	6500	5q31	Hs.171626 Hs.710433	63	protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
201371_s_at	-0.533	9.427	-3.074	7.615e-03	0.199	-2.434	CUL3	cullin 3	2	-225043112	AF062537	8452	2q36.2	Hs.372286	39	G1/S transition of mitotic cell cycle protein binding nucleus Golgi apparatus ubiquitin-dependent protein catabolic process cell cycle arrest cyclin catabolic process positive regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
234000_s_at	0.433	6.614	3.074	7.619e-03	0.199	-2.434	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	15	63609879	AJ271091	51495	15q22.2	Hs.512973	13	molecular_function GTPase activator activity protein binding cellular_component I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity small GTPase mediated signal transduction Rho protein signal transduction membrane integral to membrane Rac protein signal transduction
200627_at	-0.653	10.402	-3.073	7.635e-03	0.199	-2.436	PTGES3	prostaglandin E synthase 3 (cytosolic)	12	-55343391	BC003005	10728	12 12q13.3	Hs.50425	36	telomere maintenance chromosome, telomeric region prostaglandin biosynthetic process telomerase activity telomerase holoenzyme complex cytoplasm fatty acid biosynthetic process signal transduction isomerase activity prostaglandin-E synthase activity unfolded protein binding
240809_at	0.398	5.045	3.073	7.635e-03	0.199	-2.436	C21orf121	chromosome 21 open reading frame 121	21	42315181	AI138282	150142	21q22.3	Hs.143833	3
229820_at	0.597	5.322	3.072	7.649e-03	0.200	-2.438	LOC440993	hypothetical LOC440993	3		BF509179	440993	3q29	Hs.709411
203349_s_at	-0.842	5.794	-3.072	7.652e-03	0.200	-2.438	ETV5	ets variant 5	3	-187246799	NM_004454	2119	3q28	Hs.43697	21	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
209799_at	-0.577	3.757	-3.072	7.654e-03	0.200	-2.438	PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	5	-40795237	AF100763	5562	5p12	Hs.43322	68	nucleotide binding activation of MAPK activity magnesium ion binding response to hypoxia protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein binding ATP binding intracellular glucose metabolic process fatty acid biosynthetic process signal transduction transferase activity fatty acid oxidation positive regulation of cholesterol biosynthetic process positive regulation of anti-apoptosis negative regulation of glucosylceramide biosynthetic process	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
209487_at	0.442	6.152	3.070	7.684e-03	0.200	-2.442	RBPMS	RNA binding protein with multiple splicing	8	30361485, 30361485	D84109	11030	8p12-p11	Hs.334587	8	nucleotide binding RNA binding protein binding RNA processing
1554287_at	-0.553	4.870	-3.069	7.686e-03	0.200	-2.442	TRIM4	tripartite motif-containing 4	7	-99325971	BC011763	89122	7q22-q31.1	Hs.50749	8	protein binding intracellular cytoplasm zinc ion binding metal ion binding protein trimerization
205836_s_at	-0.712	5.254	-3.069	7.691e-03	0.200	-2.443	YTHDC2	YTH domain containing 2	5	112877308	NM_022828	64848	5q22.2	Hs.231942	6	nucleotide binding nucleic acid binding helicase activity ATP binding hydrolase activity
238177_at	0.317	5.248	3.069	7.696e-03	0.200	-2.443	SLC6A19	solute carrier family 6 (neutral amino acid transporter), member 19	5	1254709	AA873542	340024	5p15.33	Hs.481478	10	neurotransmitter:sodium symporter activity integral to plasma membrane neurotransmitter transport neutral amino acid transmembrane transporter activity symporter activity neutral amino acid transport membrane
223012_at	-0.639	8.695	-3.068	7.707e-03	0.200	-2.445	UBXN6	UBX domain protein 6	19	-4396260	AF272894	80700	19p13	Hs.435255 Hs.661664	6	molecular_function protein binding cellular_component nucleus cytoplasm centrosome biological_process modification-dependent protein catabolic process
206001_at	0.308	4.812	3.067	7.724e-03	0.201	-2.446	NPY	neuropeptide Y	7	24290333	NM_000905	4852	7p15.1	Hs.1832	144	G-protein-coupled receptor binding G-protein coupled receptor activity neuropeptide hormone activity calcium channel regulator activity extracellular region extracellular space cell calcium ion transport cell motion G-protein signaling, coupled to cyclic nucleotide second messenger neuropeptide signaling pathway synaptic transmission digestion regulation of blood pressure cell proliferation adult feeding behavior positive regulation of appetite	Adipocytokine signaling pathway
236321_at	0.514	5.266	3.067	7.729e-03	0.201	-2.447	LOC285550	hypothetical protein LOC285550	4	15292449	AW439843	285550	4p15.32	Hs.399980 Hs.619367	3
208946_s_at	-0.570	8.279	-3.066	7.746e-03	0.201	-2.449	BECN1	beclin 1, autophagy related	17	-38215675	AF139131	8678	17q21	Hs.716464	56	protein binding cytoplasm Golgi apparatus trans-Golgi network autophagy anti-apoptosis cellular defense response negative regulation of cell proliferation response to virus membrane cytoplasmic membrane-bounded vesicle positive regulation of macroautophagy protein complex	Regulation of autophagy
208718_at	-0.307	10.589	-3.065	7.757e-03	0.201	-2.450	DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	22	-37209388, -37209388	Z97056	10521	22q13.1	Hs.528305 Hs.665429 Hs.719084	28	nucleotide binding RNA binding RNA helicase activity ATP binding nucleus RNA processing ATP-dependent helicase activity RNA-dependent ATPase activity hydrolase activity
201241_at	-0.534	9.959	-3.064	7.775e-03	0.201	-2.453	DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	2	15649220	NM_004939	1653	2p24	Hs.440599	24	nucleotide binding spliceosome assembly RNA binding RNA helicase activity protein binding ATP binding cellular_component regulation of translational initiation multicellular organismal development ATP-dependent helicase activity hydrolase activity ribonucleoprotein complex
1554774_at	-0.575	4.865	-3.064	7.780e-03	0.202	-2.453	MINA	MYC induced nuclear antigen	3	-99143350, -99143350	AB083191	84864	3q11.2	Hs.607776	15	nucleus nucleolus cytoplasm ribosome biogenesis
224718_at	-0.448	6.823	-3.063	7.787e-03	0.202	-2.454	YY1	YY1 transcription factor	14	99774854	AK025731	7528	14q	Hs.388927	97	transcription factor activity transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus transcription factor complex plasma membrane regulation of transcription from RNA polymerase II promoter zinc ion binding anterior/posterior pattern formation nuclear matrix PcG protein complex metal ion binding camera-type eye morphogenesis
228316_at	0.510	4.186	3.063	7.788e-03	0.202	-2.454	C2orf63	chromosome 2 open reading frame 63	2	-55253187, -55253187	AA905470	130162	2p16.1	Hs.347014	4	binding
223253_at	-0.554	9.630	-3.062	7.803e-03	0.202	-2.456	EPDR1	ependymin related protein 1 (zebrafish)	7	37926687	BC000686	54749	7p14.1	Hs.563491	7	calcium ion binding extracellular region lysosome cell-matrix adhesion
220611_at	0.333	4.182	3.060	7.829e-03	0.202	-2.459	DAB1	disabled homolog 1 (Drosophila)	1	-57236166	NM_021080	1600	1p32-p31	Hs.477370	37	multicellular organismal development nervous system development cell differentiation
221272_s_at	-0.920	7.422	-3.060	7.832e-03	0.202	-2.459	C1orf21	chromosome 1 open reading frame 21	1	182622772	NM_030806	81563	1q25	Hs.497159 Hs.719188	8
217542_at	-0.380	4.898	-3.060	7.839e-03	0.202	-2.460	MDM2	Mdm2 p53 binding protein homolog (mouse)	12	67488237, 67489063	BE930512	4193	12q14.3-q15	Hs.484551	555	negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding	Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia
212185_x_at	-0.852	10.784	-3.060	7.841e-03	0.202	-2.460	MT2A	metallothionein 2A	16	55199978	NM_005953	4502	16q13	Hs.647371	53	protein binding cellular copper ion homeostasis zinc ion binding metal ion binding
211665_s_at	-1.006	5.476	-3.060	7.844e-03	0.202	-2.461	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	L20686	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
227666_at	0.285	4.735	3.059	7.850e-03	0.202	-2.461	DCLK2	doublecortin-like kinase 2	4	151219529	AI523594	166614	4q31.23-q31.3	Hs.591683	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation intracellular signaling cascade transferase activity
40687_at	0.398	6.474	3.059	7.859e-03	0.202	-2.462	GJA4	gap junction protein, alpha 4, 37kDa	1	35031185	M96789	2701	1p35.1	Hs.296310	47	blood vessel development plasma membrane integral to plasma membrane connexon complex transport cell-cell junction assembly cell communication cell junction
202814_s_at	-0.741	7.357	-3.058	7.866e-03	0.202	-2.463	HEXIM1	hexamethylene bis-acetamide inducible 1	17	40580466	AW193511	10614	17q21.31	Hs.586945 Hs.634944 Hs.716487	28	negative regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm heart development specific transcriptional repressor activity snRNA binding regulation of transcription negative regulation of cyclin-dependent protein kinase activity
243439_at	0.525	5.722	3.057	7.882e-03	0.203	-2.465	ZNF418	zinc finger protein 418	19	-63125063	AI971569	147686	19q13.43	Hs.660728	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1553757_at	0.377	5.085	3.056	7.908e-03	0.203	-2.468	IQCG	IQ motif containing G	3	-199100344, -199100343	NM_032263	84223	3q29	Hs.591675	6
229809_at	-0.508	5.722	-3.053	7.943e-03	0.204	-2.472	POU6F1	POU class 6 homeobox 1	12	-49866986, -49866986	AW445212	5463	12q13.13	Hs.555886	10	transcription factor activity nucleus regulation of transcription, DNA-dependent brain development heart development muscle organ development sequence-specific DNA binding
209533_s_at	-0.522	7.344	-3.053	7.955e-03	0.204	-2.473	PLAA	phospholipase A2-activating protein	9	-26893368	AF145020	9373	9p21	Hs.27182	15	protein binding phospholipid metabolic process inflammatory response signal transduction phospholipase A2 activator activity
225978_at	-0.834	5.474	-3.053	7.955e-03	0.204	-2.473	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AW409794	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
215932_at	0.332	3.175	3.052	7.959e-03	0.204	-2.474	MAGEC2	melanoma antigen family C, 2	X	-141117795	AL031073	51438	Xq27	Hs.123536	14	nucleus cytoplasm
203235_at	0.297	6.272	3.051	7.977e-03	0.204	-2.476	THOP1	thimet oligopeptidase 1	19	2736505	NM_003249	7064	19q13.3	Hs.78769	24	metalloendopeptidase activity protein binding cytoplasm proteolysis peptide metabolic process protein kinase cascade peptidase activity zinc ion binding metal ion binding	Renin-angiotensin system
212429_s_at	-0.411	7.412	-3.051	7.980e-03	0.204	-2.476	GTF3C2	general transcription factor IIIC, polypeptide 2, beta 110kDa	2	-27402224	AW194657	2976	2p23.3	Hs.75782	18	transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity protein binding nucleus mitochondrion peroxisome transcription, DNA-dependent oxygen and reactive oxygen species metabolic process 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter
225203_at	0.761	8.671	3.050	8.000e-03	0.205	-2.478	PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	8	145692916	AI742931	84988	8q24.3	Hs.521937	9	protein binding plasma membrane
204458_at	-0.466	5.720	-3.049	8.008e-03	0.205	-2.479	PLA2G15	phospholipase A2, group XV	16	66836747	AL110209	23659	16q22.1	Hs.632199	17	phosphatidylcholine-sterol O-acyltransferase activity lysophospholipase activity phospholipid binding extracellular region soluble fraction lysosome lipid metabolic process ceramide metabolic process acyltransferase activity fatty acid catabolic process transferase activity hydrolase activity calcium-independent phospholipase A2 activity	Glycerophospholipid metabolism Lysosome
216320_x_at	0.351	6.099	3.049	8.017e-03	0.205	-2.480	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	3	-49696384	U37055	4485	3p21	Hs.349110 Hs.512587	31	catalytic activity serine-type endopeptidase activity calcium ion binding extracellular region proteolysis blood coagulation biological_process
226466_s_at	-0.440	7.202	-3.048	8.032e-03	0.205	-2.482	FAM58A	family with sequence similarity 58, member A	X	-152506576	AL544688	92002	Xq28	Hs.496943 Hs.659433	6
202353_s_at	-0.477	9.140	-3.047	8.041e-03	0.205	-2.483	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	17	-62767081, -62767080	NM_002816	5718	17q24.2	Hs.646575	39	protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
207087_x_at	0.486	11.167	3.046	8.058e-03	0.206	-2.485	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_020478	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
212966_at	0.598	3.806	3.046	8.059e-03	0.206	-2.485	HIC2	hypermethylated in cancer 2	22	20101692	AL043112	23119	22q11.21	Hs.632767	12	DNA binding intracellular nucleus protein C-terminus binding zinc ion binding regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding
224777_s_at	-0.331	7.755	-3.046	8.069e-03	0.206	-2.486	PAFAH1B2	platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa)	11	116520249	BG386322	5049	11q23	Hs.718419	15	1-alkyl-2-acetylglycerophosphocholine esterase activity protein binding cytoplasm spermatogenesis lipid catabolic process hydrolase activity, acting on ester bonds	Ether lipid metabolism Metabolic pathways
242146_at	0.514	5.300	3.045	8.073e-03	0.206	-2.487	SNRPA1	small nuclear ribonucleoprotein polypeptide A'	15	-99639237	AA872471	6627	15q26.3	Hs.528763	22	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex U2 snRNP RNA splicing
1566147_a_at	0.405	5.322	3.045	8.073e-03	0.206	-2.487	LOC375010	ankyrin repeat domain 20 family, member A pseudogene	1		AK098337	375010	1q21.1	Hs.672092	1
221503_s_at	-0.973	9.038	-3.044	8.100e-03	0.206	-2.490	KPNA3	karyopherin alpha 3 (importin alpha 4)	13	-49171444	AF034756	3839	13q14.3	Hs.527919	61	protein binding nucleus nuclear pore cytoplasm protein complex assembly NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity
225674_at	-0.653	8.510	-3.044	8.101e-03	0.206	-2.490	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	AW873330	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
212843_at	-0.830	5.000	-3.043	8.108e-03	0.206	-2.491	NCAM1	neural cell adhesion molecule 1	11	112337204, 112337204	AA126505	4684	11q23.1	Hs.503878	120	protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane	Cell adhesion molecules (CAMs) Prion diseases
223424_s_at	-0.416	6.552	-3.043	8.109e-03	0.206	-2.491	ZSCAN21	zinc finger and SCAN domain containing 21	7	99485352	AL136865	7589	7q22.1	Hs.632294	9	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription activator activity metal ion binding
201362_at	-0.719	6.719	-3.043	8.114e-03	0.206	-2.491	IVNS1ABP	influenza virus NS1A binding protein	1	-183532144	AF205218	10625	1q25.1-q31.1	Hs.497183	9	protein binding nucleus nucleoplasm transcription factor complex spliceosomal complex cytoplasm cytoskeleton transcription from RNA polymerase III promoter RNA splicing response to virus interspecies interaction between organisms
221539_at	0.751	7.538	3.043	8.115e-03	0.206	-2.491	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	8	38007176	AB044548	1978	8p12	Hs.411641	107	protein binding cytosol eukaryotic initiation factor 4E binding insulin receptor signaling pathway negative regulation of translational initiation	ErbB signaling pathway mTOR signaling pathway Insulin signaling pathway Acute myeloid leukemia
226484_at	-0.433	8.379	-3.043	8.115e-03	0.206	-2.491	ZBTB47	zinc finger and BTB domain containing 47	3	42675877	AA532640	92999	3p22.1	Hs.409561	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
223386_at	-0.584	6.702	-3.043	8.119e-03	0.206	-2.492	FAM118B	family with sequence similarity 118, member B	11	125586828	BC001647	79607	11q24.2	Hs.276315	2
203232_s_at	-0.701	7.933	-3.042	8.125e-03	0.206	-2.492	ATXN1	ataxin 1	6	-16407321	NM_000332	6310	6p23	Hs.434961 Hs.712106	65	RNA binding nucleus nucleoplasm nucleolus cytoplasm RNA processing protein C-terminus binding cell death poly(U) RNA binding adult locomotory behavior visual learning nuclear matrix negative regulation of transcription transcription repressor activity poly(G) RNA binding nuclear RNA export factor complex negative regulation of phosphorylation nuclear inclusion body identical protein binding negative regulation of insulin-like growth factor receptor signaling pathway protein self-association positive regulation of transcription from RNA polymerase II promoter nuclear export regulation of excitatory postsynaptic membrane potential
1569906_s_at	-0.404	6.371	-3.042	8.128e-03	0.206	-2.493	PHF20	PHD finger protein 20	20	33823336	BC015538	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212885_at	-0.582	7.356	-3.042	8.131e-03	0.206	-2.493	MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)	2	71210951	AL545921	10199	2p13.3	Hs.656208	10	protein binding nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing RNA splicing RNA splicing factor activity, transesterification mechanism
1565329_at	0.557	2.450	3.041	8.147e-03	0.206	-2.495	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	2	75039282	AY034104	56655	2p12	Hs.469060	5	DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
201580_s_at	-0.609	7.082	-3.039	8.173e-03	0.207	-2.498	TMX4	thioredoxin-related transmembrane protein 4	20	-7909715	AL544094	56255	20p12	Hs.169358	11	mitochondrion transport membrane integral to membrane electron transport chain cell redox homeostasis
226090_x_at	-0.518	5.883	-3.039	8.174e-03	0.207	-2.498	RABL3	RAB, member of RAS oncogene family-like 3	3	-121888217	AK025772	285282	3q13.33	Hs.444360	1	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
225921_at	-0.945	7.246	-3.039	8.174e-03	0.207	-2.498	NIN	ninein (GSK3B interacting protein)	14	-50263700, -50262296, -50262296, -50256230	AL359571	51199	14q22.1	Hs.310429	23	nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization
201402_at	0.273	7.495	3.039	8.185e-03	0.207	-2.499	ADRBK1	adrenergic, beta, receptor kinase 1	11	66790480	NM_001619	156	11q13.1	Hs.83636	98	nucleotide binding regulation of the force of heart contraction desensitization of G-protein coupled receptor protein signaling pathway negative regulation of the force of heart contraction by chemical signal G-protein coupled receptor kinase activity signal transducer activity protein binding ATP binding soluble fraction cytoplasm signal transduction muscarinic acetylcholine receptor signaling pathway tachykinin receptor signaling pathway heart development membrane transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation positive regulation of catecholamine secretion negative regulation of striated muscle contraction beta-adrenergic receptor kinase activity cardiac muscle contraction	Chemokine signaling pathway Endocytosis
210418_s_at	0.619	10.152	3.039	8.186e-03	0.207	-2.499	IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	20	-2587040	AF023265	3420	20p13	Hs.436405	14	magnesium ion binding isocitrate dehydrogenase (NAD+) activity mitochondrion mitochondrial matrix tricarboxylic acid cycle isocitrate metabolic process visual perception electron carrier activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding response to stimulus NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
214359_s_at	-0.499	9.104	-3.039	8.187e-03	0.207	-2.499	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	6	44322826	AI218219	3326	6p12	Hs.509736 Hs.689683 Hs.701787	50	nucleotide binding ATP binding cytoplasm protein folding response to unfolded protein nitric-oxide synthase regulator activity TPR domain binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process melanosome positive regulation of nitric oxide biosynthetic process unfolded protein binding regulation of interferon-gamma-mediated signaling pathway regulation of type I interferon-mediated signaling pathway	Antigen processing and presentation Pathways in cancer Prostate cancer
220924_s_at	-1.015	9.558	-3.038	8.195e-03	0.207	-2.500	SLC38A2	solute carrier family 38, member 2	12	-45038238	NM_018976	54407	12q	Hs.221847	20	plasma membrane ion transport sodium ion transport amino acid transport symporter activity integral to membrane sodium ion binding
230009_at	-0.543	6.502	-3.038	8.197e-03	0.207	-2.501	FAM118B	family with sequence similarity 118, member B	11	125586828	AI936072	79607	11q24.2	Hs.276315	2
207616_s_at	-0.628	8.047	-3.037	8.209e-03	0.207	-2.502	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	NM_004180	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
201456_s_at	-0.616	6.348	-3.037	8.210e-03	0.207	-2.502	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	10	124903749	AU160695	9184	10q26	Hs.418533	28	kinetochore protein binding nucleus nucleolus cytosol mitosis mitotic cell cycle checkpoint cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle
216197_at	0.385	4.660	3.037	8.212e-03	0.207	-2.502	ATF7IP	activating transcription factor 7 interacting protein	12	14409877	AK021569	55729	12p13.1	Hs.714407	17	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding nucleus transcription factor complex cytoplasm DNA methylation ATPase activity interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent regulation of transcriptional preinitiation complex assembly
223465_at	-0.678	6.401	-3.037	8.217e-03	0.207	-2.503	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	5	-74702683, -74702683	BE967275	10087	5q13.3	Hs.270437	26	protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response
213741_s_at	-1.115	5.508	-3.037	8.222e-03	0.207	-2.503	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	BF575685	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
202601_s_at	-0.477	5.129	-3.036	8.240e-03	0.207	-2.505	HTATSF1	HIV-1 Tat specific factor 1	X	135406903, 135407336	AI373539	27336	Xq26.1-q27.2	Hs.204475	27	nucleotide binding RNA polymerase II transcription factor activity transcription elongation regulator activity RNA binding protein binding nucleus nucleolus regulation of transcription from RNA polymerase II promoter viral genome replication regulation of transcription
218438_s_at	-0.566	7.314	-3.035	8.253e-03	0.207	-2.507	MED28	mediator complex subunit 28	4	17225370	NM_025205	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
225658_at	-0.652	7.263	-3.035	8.255e-03	0.207	-2.507	SPOPL	speckle-type POZ protein-like	2	138975819	BF034206	339745	2q22.1	Hs.333297	6	protein binding nucleus modification-dependent protein catabolic process
205872_x_at	-0.762	11.364	-3.034	8.267e-03	0.207	-2.508	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	NM_022359	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
212259_s_at	-0.504	7.591	-3.034	8.273e-03	0.207	-2.509	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	1	-153183179	BF344265	57326	1q21.3	Hs.505806	8	transcription corepressor activity protein binding nucleus cytoplasm cytosol cytoskeleton microtubule multicellular organismal development negative regulation of transcription cell differentiation
202873_at	0.283	4.301	3.034	8.273e-03	0.207	-2.509	ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	8	104102423	BF034973	528	8q22.3	Hs.86905	19	transporter activity protein binding plasma membrane ion transport ATP synthesis coupled proton transport proton transport proton-transporting two-sector ATPase complex hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances proton-transporting V-type ATPase, V1 domain proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
1558556_at	0.395	4.450	3.033	8.277e-03	0.207	-2.509	CAMK1	calcium/calmodulin-dependent protein kinase I	3	-9774030	AL041824	8536	3p25.3	Hs.434875	31	nucleotide binding calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm protein amino acid phosphorylation nucleocytoplasmic transport signal transduction multicellular organismal development nervous system development transferase activity cell differentiation
211330_s_at	0.344	4.123	3.033	8.278e-03	0.207	-2.509	HFE	hemochromatosis	6	26195487	AF144242	3077	6p21.3	Hs.233325	592	antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome
225152_at	-0.431	7.232	-3.033	8.282e-03	0.207	-2.510	ZNF622	zinc finger protein 622	5	-16504627	BF940944	90441	5p15.1	Hs.60300	5	nucleic acid binding intracellular nucleus cytoplasm zinc ion binding metal ion binding
213750_at	-0.396	8.432	-3.032	8.293e-03	0.207	-2.511	RSL1D1	ribosomal L1 domain containing 1	16	-11835555	AA928506	26156	16p13.13	Hs.401842	17	RNA binding structural constituent of ribosome protein binding intracellular nucleus nucleolus ribosome RNA processing translation regulation of protein localization
212533_at	-0.799	6.044	-3.032	8.296e-03	0.207	-2.511	WEE1	WEE1 homolog (S. pombe)	11	9551803, 9552809	X62048	7465	11p15.3-p15.1	Hs.249441	61	nucleotide binding magnesium ion binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division	Cell cycle
231995_at	-0.623	4.497	-3.032	8.302e-03	0.207	-2.512	C9orf82	chromosome 9 open reading frame 82	9	-26830682	AF131768	79886	9p21.2	Hs.178357	10
241819_at	0.415	2.951	3.032	8.305e-03	0.207	-2.512	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	9	-116704944	AW518486	944	9q33	Hs.654445	19	cytokine activity tumor necrosis factor receptor binding extracellular space integral to plasma membrane induction of apoptosis immune response signal transduction cell-cell signaling cell proliferation membrane	Cytokine-cytokine receptor interaction
212293_at	-0.628	7.620	-3.031	8.310e-03	0.207	-2.513	HIPK1	homeodomain interacting protein kinase 1	1	114273518, 114273518, 114295289, 114298021	BG111260	204851	1p13.2	Hs.532363	11	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleolus cytoplasm centrosome protein amino acid phosphorylation transferase activity regulation of transcription
228988_at	1.405	4.851	3.031	8.311e-03	0.207	-2.513	ZNF711	zinc finger protein 711	X	84385652	AU157017	7552	Xq21.1-q21.2	Hs.326801	7	DNA binding intracellular nucleus zinc ion binding transcription regulator activity regulation of transcription metal ion binding
202748_at	-1.117	7.016	-3.030	8.332e-03	0.207	-2.515	GBP2	guanylate binding protein 2, interferon-inducible	1	-89345897	NM_004120	2634	1p22.2	Hs.386567	13	nucleotide binding GTPase activity GTP binding plasma membrane immune response
208709_s_at	-0.408	9.962	-3.030	8.333e-03	0.207	-2.515	NRD1	nardilysin (N-arginine dibasic convertase)	1	-52027453	U64898	4898	1p32.2-p32.1	Hs.584782	18	metalloendopeptidase activity protein binding cytosol proteolysis neuromuscular junction development peptidase activity zinc ion binding cell proliferation cell surface cell migration metal ion binding epidermal growth factor binding positive regulation of membrane protein ectodomain proteolysis regulation of endopeptidase activity
204223_at	0.586	5.014	3.030	8.334e-03	0.207	-2.516	PRELP	proline/arginine-rich end leucine-rich repeat protein	1	201711505	NM_002725	5549	1q32	Hs.632481	13	skeletal system development extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix cell aging
226599_at	0.409	5.277	3.030	8.338e-03	0.207	-2.516	FHDC1	FH2 domain containing 1	4	154083584	AA527080	85462	4q31.3	Hs.132629	5	actin binding cellular component organization actin cytoskeleton organization
209024_s_at	-0.612	7.262	-3.030	8.339e-03	0.207	-2.516	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	AI472757	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
219408_at	-0.445	6.260	-3.030	8.339e-03	0.207	-2.516	PRMT7	protein arginine methyltransferase 7	16	66902445	NM_019023	54496	16q22.1	Hs.712584	9	spliceosomal snRNP biogenesis nucleus cytoplasm cytosol genetic imprinting S-adenosylmethionine-dependent methyltransferase activity [myelin basic protein]-arginine N-methyltransferase activity chromatin modification transferase activity peptidyl-arginine methylation cell differentiation histone arginine methylation protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N symmetric methyltransferase activity protein-arginine omega-N symmetric methyltransferase activity histone binding ribonucleoprotein binding DNA methylation during gametogenesis regulation of protein binding histone methyltransferase activity (H4-R3 specific) regulation of transcription
205752_s_at	0.416	5.874	3.030	8.340e-03	0.207	-2.516	GSTM5	glutathione S-transferase mu 5	1	110056386	NM_000851	2949	1p13.3	Hs.75652	15	glutathione transferase activity cytoplasm metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
214088_s_at	0.271	5.204	3.030	8.340e-03	0.207	-2.516	FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	19	-5793898	AW080549	2525	19p13.3	Hs.169238	55	membrane fraction Golgi apparatus carbohydrate metabolic process protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
206235_at	-0.529	4.536	-3.028	8.361e-03	0.207	-2.519	LIG4	ligase IV, DNA, ATP-dependent	13	-107657792, -107657792, -107657792	NM_002312	3981	13q33-q34	Hs.166091	82	single strand break repair nucleotide binding magnesium ion binding condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding DNA ligase (ATP) activity ATP binding intracellular nucleus cytoplasm plasma membrane focal adhesion DNA-dependent protein kinase-DNA ligase 4 complex DNA replication nucleotide-excision repair, DNA gap filling double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus cell cycle central nervous system development protein C-terminus binding cell proliferation response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination T cell receptor V(D)J recombination somatic stem cell maintenance negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA recombination DNA ligation during DNA repair DNA ligation during DNA repair chromosome organization cell division	Non-homologous end-joining
211060_x_at	-0.377	8.053	-3.028	8.365e-03	0.207	-2.519	GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	8	145209511	BC006383	8733	8q24.3	Hs.627962	16	GPI-anchor transamidase activity protein binding endoplasmic reticulum protein complex assembly protein retention in ER lumen tubulin binding membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein attachment of GPI anchor to protein GPI anchor binding GPI-anchor transamidase complex	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
227780_s_at	0.446	6.601	3.028	8.365e-03	0.207	-2.519	ECSCR	endothelial cell-specific chemotaxis regulator	5	-138812143	AI422211	641700	5q31.2	Hs.483538 Hs.570903	5	angiogenesis plasma membrane chemotaxis multicellular organismal development integral to membrane cell differentiation
207284_s_at	-0.604	6.962	-3.028	8.367e-03	0.207	-2.519	ASPH	aspartate beta-hydroxylase	8	-62739837, -62699648, -62699648, -62575669	NM_020164	444	8q12.1	Hs.591874	24	peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis
221766_s_at	-0.519	6.569	-3.028	8.372e-03	0.207	-2.520	FAM46A	family with sequence similarity 46, member A	6	-82512165	AW246673	55603	6q14	Hs.10784	11
219065_s_at	-0.679	9.125	-3.027	8.379e-03	0.207	-2.521	MEMO1	mediator of cell motility 1	2	-31946398, -31946397	NM_015955	51072	2p22-p21	Hs.444969	10	nucleus cytosol
201926_s_at	-0.618	7.311	-3.027	8.390e-03	0.208	-2.522	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	1	205561439	BC001288	1604	1q32	Hs.126517	118	soluble fraction plasma membrane integral to plasma membrane complement activation, classical pathway elevation of cytosolic calcium ion concentration anchored to membrane innate immune response membrane raft respiratory burst	Complement and coagulation cascades Hematopoietic cell lineage
212103_at	-0.468	7.476	-3.027	8.391e-03	0.208	-2.522	KPNA6	karyopherin alpha 6 (importin alpha 7)	1	32346230	BG403834	23633	1p35.1-p34.3	Hs.470588 Hs.711019	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
204592_at	0.488	4.637	3.026	8.398e-03	0.208	-2.523	DLG4	discs, large homolog 4 (Drosophila)	17	-7033935, -7033933	NM_001365	1742	17p13.1	Hs.463928	119	cytoplasm plasma membrane protein complex assembly signal transduction synaptic transmission nervous system development learning protein C-terminus binding postsynaptic density synaptic vesicle maturation synaptosome cell junction cortical cytoskeleton extrinsic to internal side of plasma membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex synapse postsynaptic membrane regulation of long-term neuronal synaptic plasticity	Huntington's disease
217816_s_at	-0.417	9.041	-3.026	8.404e-03	0.208	-2.523	PCNP	PEST proteolytic signal containing nuclear protein	3	102775731	NM_020357	57092	3q12.3	Hs.545311 Hs.654949	6	protein binding nucleus cell cycle protein ubiquitination proteasomal ubiquitin-dependent protein catabolic process
209674_at	-0.685	6.958	-3.026	8.406e-03	0.208	-2.523	CRY1	cryptochrome 1 (photolyase-like)	12	-105909271	D83702	1407	12q23-q24.1	Hs.151573	23	nucleotide binding DNA binding DNA photolyase activity nucleus cytoplasm mitochondrion DNA repair circadian rhythm G-protein coupled photoreceptor activity protein-chromophore linkage regulation of transcription response to stimulus	Circadian rhythm - mammal
217717_s_at	-0.446	8.101	-3.025	8.418e-03	0.208	-2.525	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	20	42947757	BF246499	7529	20q13.1	Hs.643544	109	cytoplasm cytosol protein targeting Ras protein signal transduction activation of pro-apoptotic gene products enzyme binding protein domain specific binding negative regulation of protein amino acid dephosphorylation melanosome positive regulation of catalytic activity perinuclear region of cytoplasm	Cell cycle Neurotrophin signaling pathway
208630_at	0.482	9.543	3.024	8.428e-03	0.208	-2.526	HADHA	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	2	-26267007	AI972144	3030	2p23	Hs.516032	36	acyl-CoA binding 3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity fatty acid beta-oxidation multienzyme complex long-chain-enoyl-CoA hydratase activity long-chain-3-hydroxyacyl-CoA dehydrogenase activity lyase activity response to drug mitochondrial nucleoid NAD or NADH binding oxidation reduction	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Biosynthesis of unsaturated fatty acids Metabolic pathways
205120_s_at	-0.508	8.075	-3.024	8.433e-03	0.208	-2.526	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	4	-52581617	U29586	6443	4q12	Hs.438953	28	cytoplasm cytoskeleton plasma membrane integral to plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
223143_s_at	-0.843	5.361	-3.024	8.435e-03	0.208	-2.527	AKIRIN2	akirin 2	6	-88441298	AI742378	55122	6q15	Hs.485915	10	protein binding nucleus embryonic development transcriptional repressor complex response to lipopolysaccharide positive regulation of interleukin-6 production innate immune response regulation of transcription positive regulation of transcription from RNA polymerase II promoter
226525_at	-0.534	5.070	-3.024	8.436e-03	0.208	-2.527	STK17B	serine/threonine kinase 17b	2	-196706552	N51102	9262	2q32.3	Hs.710234 Hs.88297	7	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade actin cytoskeleton transferase activity
211220_s_at	-1.201	4.581	-3.024	8.439e-03	0.208	-2.527	HSF2	heat shock transcription factor 2	6	122762394	BC005329	3298	6q22.31	Hs.158195	28	transcription factor activity transcription coactivator activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress spermatogenesis protein homodimerization activity sequence-specific DNA binding
224878_at	-0.475	8.142	-3.024	8.439e-03	0.208	-2.527	UBFD1	ubiquitin family domain containing 1	16	23476362	N63936	56061	16p12	Hs.3459	3
202372_at	-0.366	6.772	-3.024	8.443e-03	0.208	-2.527	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	BF240652	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
209211_at	-1.362	4.661	-3.023	8.457e-03	0.208	-2.529	KLF5	Kruppel-like factor 5 (intestinal)	13	72531142	AF132818	688	13q22.1	Hs.508234	50	angiogenesis transcription factor activity RNA polymerase II transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter zinc ion binding positive regulation of cell proliferation microvillus assembly positive regulation of transcription metal ion binding
214505_s_at	-1.025	12.494	-3.023	8.459e-03	0.208	-2.529	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF220153	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
209613_s_at	1.257	6.961	3.022	8.474e-03	0.208	-2.531	ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	4	-100446549	M21692	125	4q21-q23	Hs.4	193	alcohol dehydrogenase (NAD) activity binding cytoplasm ethanol oxidation zinc ion binding oxidoreductase activity metal ion binding oxidation reduction	Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
225267_at	-0.709	9.492	-3.021	8.484e-03	0.208	-2.532	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	AI935246	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
228624_at	0.381	4.156	3.021	8.487e-03	0.208	-2.532	TMEM144	transmembrane protein 144	4	159350850	AI432488	55314	4q32.1	Hs.718582	2	membrane integral to membrane
209821_at	0.558	3.848	3.021	8.488e-03	0.208	-2.532	IL33	interleukin 33	9	6231677	AB024518	90865	9p24.1	Hs.348390	32	cytokine activity protein binding extracellular region extracellular space
203841_x_at	-0.454	4.718	-3.021	8.493e-03	0.208	-2.533	MAPRE3	microtubule-associated protein, RP/EB family, member 3	2	27047028	BG222594	22924	2p23.3-p23.1	Hs.515860	13	small GTPase regulator activity cytoplasm microtubule cell cycle mitosis microtubule binding midbody positive regulation of gene-specific transcription cell division
223468_s_at	-0.648	7.311	-3.020	8.508e-03	0.209	-2.534	RGMA	RGM domain family, member A	15	-91387640	AL136826	56963	15q26.1	Hs.271277	16	neural tube closure endoplasmic reticulum plasma membrane cell surface regulation of BMP signaling pathway anchored to membrane
228087_at	-0.390	7.124	-3.020	8.509e-03	0.209	-2.534	CCDC126	coiled-coil domain containing 126	7	23603522	AK026684	90693	7p15.3	Hs.232296	4	extracellular region
228376_at	0.566	5.826	3.019	8.532e-03	0.209	-2.537	GGTA1	glycoprotein, alpha-galactosyltransferase 1	9	-123257139	AI972498	2681	9q33.2-q34.11	Hs.97469	6	Golgi apparatus carbohydrate metabolic process membrane integral to membrane transferase activity, transferring hexosyl groups
205584_at	-0.359	6.114	-3.018	8.548e-03	0.209	-2.539	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_024810	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
224520_s_at	-1.231	6.695	-3.017	8.555e-03	0.209	-2.539	BEST3	bestrophin 3	12	-68333655, -68333655	BC006440	144453	12q14.2-q15	Hs.280782	7	molecular_function ion channel activity chloride channel activity calcium ion binding plasma membrane ion transport biological_process integral to membrane chloride ion binding chloride channel complex
203977_at	0.316	7.185	3.017	8.559e-03	0.209	-2.540	TAZ	tafazzin	X	153293070	NM_000116	6901	Xq28	Hs.409911	35	cytoplasm mitochondrion mitochondrion muscle contraction skeletal muscle tissue development metabolic process acyltransferase activity membrane integral to membrane hemopoiesis cardiolipin biosynthetic process mitochondrial respiratory chain complex I assembly cristae formation mitochondrial ATP synthesis coupled electron transport 1-acylglycerophosphocholine O-acyltransferase activity cardiac muscle tissue development cardiac muscle contraction
227865_at	0.438	5.673	3.016	8.576e-03	0.209	-2.542	C9orf103	chromosome 9 open reading frame 103	9	85427785	BF111242	414328	9q21-q22	Hs.530261	1	nucleotide binding molecular_function shikimate kinase activity ATP binding cellular_component carbohydrate metabolic process biological_process transferase activity gluconokinase activity
229092_at	-0.452	5.750	-3.016	8.579e-03	0.209	-2.542	NR2F2	nuclear receptor subfamily 2, group F, member 2	15	94670160, 94675114, 94676797, 94677572	AI420144	7026	15q26	Hs.657455	27	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding
222679_s_at	-0.747	5.615	-3.016	8.583e-03	0.209	-2.542	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	3	-184143252	AW468880	54165	3q26.3	Hs.715661	16	molecular_function cellular_component biological_process modification-dependent protein catabolic process
217839_at	-0.522	8.919	-3.015	8.586e-03	0.209	-2.543	TFG	TRK-fused gene	3	101910849	NM_006070	10342	3q12.2	Hs.518123	25	signal transducer activity cytoplasm identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade	Pathways in cancer Thyroid cancer
1557211_a_at	-0.556	3.385	-3.013	8.622e-03	0.210	-2.547	C14orf86	chromosome 14 open reading frame 86	14	-93440828	BC037859	283592	14q32.12	Hs.585649	1
1552729_at	0.264	4.521	3.013	8.623e-03	0.210	-2.547	SNHG7	small nucleolar RNA host gene 7 (non-protein coding)	9	-138739506, -138738868	NM_032887	84973	9q34.3	Hs.636619	2
203384_s_at	-0.362	5.872	-3.013	8.624e-03	0.210	-2.547	GOLGA1	golgi autoantigen, golgin subfamily a, 1	9	-126680394	NM_002077	2800	9q33.3	Hs.133469 Hs.59504	11	Golgi apparatus membrane
218343_s_at	-0.543	6.702	-3.013	8.637e-03	0.210	-2.548	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	2	-197337344	NM_012086	9330	2q33.1	Hs.470996	10	transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity binding nucleus transcription, DNA-dependent 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter
205738_s_at	1.170	11.432	3.012	8.648e-03	0.210	-2.549	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)	1	-31610686	NM_004102	2170	1p33-p32	Hs.657242	35	transporter activity cytoplasm phosphatidylcholine biosynthetic process transport negative regulation of cell proliferation lipid binding	PPAR signaling pathway
228256_s_at	0.495	5.578	3.012	8.655e-03	0.211	-2.550	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A	5	-111526213	AU144565	64097	5q22.1-q22.2	Hs.584954	7	binding cellular_component cytoplasm cytoskeleton cytoskeletal protein binding biological_process extrinsic to membrane
218642_s_at	0.469	7.636	3.011	8.660e-03	0.211	-2.551	CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7	8	57286868	NM_024300	79145	8q12.1	Hs.436913	9
202696_at	-0.407	8.252	-3.011	8.669e-03	0.211	-2.551	OXSR1	oxidative-stress responsive 1	3	38182029	NM_005109	9943	3p22-p21.3	Hs.475970	21	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation response to oxidative stress protein kinase cascade transferase activity identical protein binding
210862_s_at	0.338	3.986	3.010	8.687e-03	0.211	-2.553	SARDH	sarcosine dehydrogenase	9	-135518506, -135518506	AF047190	1757	9q33-q34	Hs.198003	11	aminomethyltransferase activity cytoplasm mitochondrion mitochondrial matrix glycine catabolic process sarcosine dehydrogenase activity oxidoreductase activity oxidation reduction	Glycine, serine and threonine metabolism Metabolic pathways
225606_at	0.763	6.832	3.010	8.690e-03	0.211	-2.554	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2	111594961, 111594961	AI949179	10018	2q13	Hs.469658	143	peripheral to membrane of membrane fraction in utero embryonic development B cell homeostasis B cell apoptosis kidney development myeloid cell homeostasis protein binding cytoplasm mitochondrion mitochondrial outer membrane cytosol plasma membrane induction of apoptosis cell-matrix adhesion spermatogenesis microtubule binding male gonad development activation of pro-apoptotic gene products post-embryonic development mammary gland development tube lumen formation odontogenesis of dentine-containing tooth T cell homeostasis ear development regulation of organ growth regulation of pigmentation during development spleen development thymus development post-embryonic organ morphogenesis
214901_at	0.467	5.371	3.010	8.691e-03	0.211	-2.554	ZNF8	zinc finger protein 8	19	63482129	AI671579	7554	19q13.43	Hs.590941 Hs.713519	8	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding BMP signaling pathway metal ion binding
209787_s_at	-0.397	8.343	-3.010	8.691e-03	0.211	-2.554	HMGN4	high mobility group nucleosomal binding domain 4	6	26646550	BC001282	10473	6p21.3	Hs.236774	6	chromatin DNA binding nucleus
208689_s_at	-0.515	8.190	-3.009	8.692e-03	0.211	-2.554	RPN2	ribophorin II	20	35240869	BC003560	6185	20q12-q13.1	Hs.370895	17	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum protein modification process oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine	N-Glycan biosynthesis Metabolic pathways
204194_at	-0.782	5.949	-3.009	8.698e-03	0.211	-2.554	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	21	29593090, 29593607, 29599430	NM_001186	571	21q22.11	Hs.154276	30	transcription factor activity nucleus nucleolus cytosol regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
208877_at	-0.396	7.949	-3.008	8.721e-03	0.211	-2.557	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	3	197951124	W74494	5062	3q29	Hs.518530	80	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol negative regulation of protein kinase activity apoptosis signal transduction membrane transferase activity regulation of growth identical protein binding interspecies interaction between organisms protein amino acid autophosphorylation perinuclear region of cytoplasm	MAPK signaling pathway ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
228831_s_at	0.485	6.001	3.007	8.732e-03	0.211	-2.558	GNG7	guanine nucleotide binding protein (G protein), gamma 7	19	-2462217	AL039870	2788	19p13.3	Hs.515544	12	behavioral fear response signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction receptor guanylyl cyclase signaling pathway locomotory behavior regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
234950_s_at	-0.392	6.139	-3.007	8.735e-03	0.211	-2.558	RFWD2	ring finger and WD repeat domain 2	1	-174180589	AK001278	64326	1q25.1-q25.2	Hs.523744	12	protein binding nucleus cytoplasm zinc ion binding nuclear speck ligase activity modification-dependent protein catabolic process metal ion binding	p53 signaling pathway Ubiquitin mediated proteolysis
218215_s_at	-0.426	6.227	-3.007	8.736e-03	0.211	-2.558	NR1H2	nuclear receptor subfamily 1, group H, member 2	19	55571496	NM_007121	7376	19q13.3-q13.3	Hs.432976	62	transcription factor activity steroid hormone receptor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding positive regulation of specific transcription from RNA polymerase II promoter negative regulation of foam cell differentiation positive regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux negative regulation of cholesterol storage negative regulation of transcription positive regulation of cellular protein metabolic process negative regulation of lipid transport sequence-specific DNA binding cellular lipid metabolic process positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of pinocytosis positive regulation of lipoprotein lipase activity
212343_at	-0.557	6.766	-3.007	8.741e-03	0.211	-2.559	YIPF6	Yip1 domain family, member 6	X	67635610	AL117461	286451	Xq12	Hs.700646 Hs.82719	10	endoplasmic reticulum membrane integral to membrane
225997_at	-0.829	6.658	-3.006	8.750e-03	0.211	-2.560	MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	4	71986927	AL162039	92597	4q13.3	Hs.700445 Hs.719746	6	protein binding nucleus cytoplasm zinc ion binding kinase activator activity kinase binding protein amino acid autophosphorylation metal ion binding
218393_s_at	-0.416	6.287	-3.006	8.754e-03	0.211	-2.560	SMU1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	9	-33031849	NM_018225	55234	9p12	Hs.655351	10	nucleus cytoplasm
204349_at	-0.410	6.528	-3.006	8.758e-03	0.211	-2.561	MED7	mediator complex subunit 7	5	-156498028, -156498028	BC005250	9443	5q33.3	Hs.279902 Hs.719330	15	transcription coactivator activity protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription regulator activity regulation of transcription
208152_s_at	-0.428	8.322	-3.006	8.761e-03	0.211	-2.561	DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	10	70385897	NM_004728	9188	10q21	Hs.223141 Hs.576875	18	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus nucleolus hydrolase activity
222410_s_at	-0.579	8.633	-3.005	8.764e-03	0.211	-2.561	SNX6	sorting nexin 6	14	-34100368, -34100368	AF121856	58533	14q13.1	Hs.583855	7	protein binding intracellular cytoplasm intracellular protein transport cell communication negative regulation of epidermal growth factor receptor activity negative regulation of transcription negative regulation of transforming growth factor beta receptor signaling pathway phosphoinositide binding protein homodimerization activity
203679_at	-0.467	7.476	-3.005	8.771e-03	0.211	-2.562	TMED1	transmembrane emp24 protein transport domain containing 1	19	-10804113	NM_006858	11018	19p13.2	Hs.515139	6	receptor binding plasma membrane transport signal transduction cell-cell signaling integral to membrane
222597_at	-0.764	4.963	-3.005	8.774e-03	0.211	-2.562	SNAP29	synaptosomal-associated protein, 29kDa	22	19543291	AI346639	9342	22q11.21	Hs.108002 Hs.701035	19	SNAP receptor activity cytoplasm plasma membrane exocytosis vesicle targeting membrane fusion protein transport synaptosome cell junction synapse	SNARE interactions in vesicular transport
212688_at	-0.531	7.969	-3.005	8.774e-03	0.211	-2.562	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	3	-139856920	BC003393	5291	3q22.3	Hs.239818	58	nucleotide binding activation of MAPK activity regulation of cell-matrix adhesion inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex cellular calcium ion homeostasis chemotaxis homophilic cell adhesion signal transduction G-protein coupled receptor protein signaling pathway 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor platelet activation embryonic cleavage insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
213875_x_at	-0.582	6.283	-3.005	8.777e-03	0.211	-2.563	C6orf62	chromosome 6 open reading frame 62	6	-24813069	BG252842	81688	6p22.3	Hs.519930	6	molecular_function cellular_component intracellular biological_process
1554397_s_at	-0.490	4.741	-3.005	8.779e-03	0.211	-2.563	UEVLD	UEV and lactate/malate dehyrogenase domains	11	-18509819	BC011011	55293	11p15.1	Hs.407991	5	binding glycolysis metabolic process protein transport oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor small conjugating protein ligase activity modification-dependent protein catabolic process post-translational protein modification cellular carbohydrate metabolic process regulation of protein metabolic process
226411_at	0.323	6.033	3.004	8.794e-03	0.211	-2.564	EVI5L	ecotropic viral integration site 5-like	19	7801160, 7817385	N32544	115704	19p13.2	Hs.26870	7	GTPase activator activity Rab GTPase activator activity protein binding intracellular regulation of Rab GTPase activity
1555733_s_at	0.267	2.512	3.004	8.798e-03	0.211	-2.565	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	2	-224328290	AF393369	130340	2q36.1	Hs.632555	13	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane membrane coat clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
206021_at	0.434	4.693	3.004	8.798e-03	0.211	-2.565	SCAND2	SCAN domain containing 2 pseudogene	15	82975694	NM_022050	54581	15q25-q26	Hs.658114	7	molecular_function transcription factor activity cellular_component nucleus regulation of transcription, DNA-dependent biological_process
211382_s_at	-0.540	9.133	-3.003	8.809e-03	0.211	-2.566	TACC2	transforming, acidic coiled-coil containing protein 2	10	123738678, 123913094	AF220152	10579	10q26	Hs.501252 Hs.713875	18	protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding
225463_x_at	-0.453	6.880	-3.003	8.816e-03	0.211	-2.567	GPR89A	G protein-coupled receptor 89A	1	-144475951	BF941168	653519	1q21.1	Hs.559115 Hs.645432	10	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
214769_at	-0.536	8.644	-3.003	8.816e-03	0.211	-2.567	CLCN4	chloride channel 4	X	10084984	AF052117	1183	Xp22.3	Hs.495674	17	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding
224977_at	-0.512	6.803	-3.002	8.817e-03	0.211	-2.567	C6orf89	chromosome 6 open reading frame 89	6	36961617	AL119182	221477	6p21.2	Hs.433381	10	membrane integral to membrane
214636_at	-2.016	2.674	-3.002	8.820e-03	0.211	-2.567	CALCB	calcitonin-related polypeptide beta	11	15051721	AA747379	797	11p15.2-p15.1	Hs.534305	15	neuropeptide hormone activity extracellular region soluble fraction cellular calcium ion homeostasis signal transduction vasodilation
235032_at	-0.544	8.020	-3.001	8.849e-03	0.212	-2.570	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	5	34965454	BG112118	134218	5p13.2	Hs.131887	5	nucleic acid binding intracellular zinc ion binding heat shock protein binding metal ion binding
203207_s_at	-0.571	5.109	-3.001	8.851e-03	0.212	-2.570	MTFR1	mitochondrial fission regulator 1	8	66719441, 66719441, 66744661	BF214329	9650	8q13.1	Hs.584788	8	mitochondrion plasma membrane
228452_at	-0.627	6.951	-3.001	8.852e-03	0.212	-2.570	C17orf39	chromosome 17 open reading frame 39	17	17883335	AA827865	79018	17p11.2	Hs.187422	5
209440_at	-0.423	8.355	-3.000	8.853e-03	0.212	-2.570	PRPS1	phosphoribosyl pyrophosphate synthetase 1	X	106758309	BC001605	5631	Xq21.32-q24	Hs.56	26	nucleotide binding magnesium ion binding ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding cytosol purine base metabolic process purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process kinase activity transferase activity urate biosynthetic process protein homodimerization activity hypoxanthine biosynthetic process	Pentose phosphate pathway Purine metabolism Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
1553429_at	0.353	5.026	2.999	8.882e-03	0.212	-2.573	FLJ31713	hypothetical protein FLJ31713	9		NM_152575	158263	9q32	Hs.350785	1
202212_at	-0.274	6.664	-2.999	8.886e-03	0.212	-2.574	PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)	22	-29302611	NM_014303	23481	22q12.1	Hs.517543	20	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding intracellular nucleus nucleoplasm nucleolus rRNA processing cell proliferation cell proliferation preribosome, large subunit precursor ribosomal large subunit biogenesis regulation of cell cycle PeBoW complex
201643_x_at	-0.352	8.231	-2.999	8.888e-03	0.212	-2.574	KDM3B	lysine (K)-specific demethylase 3B	5	137716183	NM_016604	51780	5q31	Hs.714832	14	iron ion binding nucleus nucleolus zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
240754_at	0.287	3.334	2.998	8.894e-03	0.212	-2.575	LOC284933	hypothetical protein LOC284933	22		AI382197	284933	22q13.32	Hs.159057	1
1555308_at	0.294	6.034	2.998	8.896e-03	0.212	-2.575	CARD14	caspase recruitment domain family, member 14	17	75766875, 75776193	BC018142	79092	17q25	Hs.675480 Hs.696253	7	positive regulation of protein amino acid phosphorylation protein binding intracellular cytoplasm plasma membrane activation of NF-kappaB-inducing kinase activity regulation of apoptosis CARD domain binding
230418_s_at	-0.848	4.456	-2.998	8.899e-03	0.212	-2.575	GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1	14	68796667	AI097463	57452	14q24.1	Hs.21035	4	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding	O-Glycan biosynthesis Metabolic pathways
219428_s_at	0.293	6.736	2.997	8.916e-03	0.212	-2.577	PXMP4	peroxisomal membrane protein 4, 24kDa	20	-31754210	BF057649	11264	20q11.22	Hs.654857	8	membrane fraction peroxisome peroxisomal membrane membrane integral to membrane
217716_s_at	-0.348	6.988	-2.997	8.919e-03	0.212	-2.577	SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	3	129253901	NM_013336	29927	3q21.3	Hs.518236	14	protein binding endoplasmic reticulum protein transport P-P-bond-hydrolysis-driven protein transmembrane transporter activity membrane integral to membrane ribosome binding intracellular protein transmembrane transport	Vibrio cholerae infection
230718_at	0.385	3.357	2.997	8.925e-03	0.212	-2.578	HSF5	heat shock transcription factor family member 5	17	-53852527	AL137385	124535	17q22	Hs.380061	1	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
229030_at	0.415	3.947	2.997	8.925e-03	0.212	-2.578	CAPN8	calpain 8	1	-221781594	AW242997	388743	1q41	Hs.291487 Hs.670199	9	calcium-dependent cysteine-type endopeptidase activity calcium ion binding intracellular cytoplasm Golgi apparatus proteolysis peptidase activity
234027_at	0.385	4.212	2.996	8.929e-03	0.212	-2.578	CCDC129	coiled-coil domain containing 129	7	31523502	AI184130	223075	7p14.3	Hs.224269	2
211609_x_at	-0.477	10.078	-2.996	8.942e-03	0.213	-2.580	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	U51007	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
228163_at	0.325	5.676	2.996	8.944e-03	0.213	-2.580	ST6GALNAC4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	9	-129709985	BE858453	27090	9q34	Hs.3972 Hs.709827	13	soluble fraction nucleus Golgi apparatus protein amino acid glycosylation glycolipid metabolic process membrane integral to membrane integral to Golgi membrane (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
229389_at	0.384	5.089	2.994	8.977e-03	0.213	-2.583	ATG16L2	ATG16 autophagy related 16-like 2 (S. cerevisiae)	11	72203098	AA741058	89849	11q13.4	Hs.653186	3	cytoplasm autophagy protein transport
228953_at	-0.598	6.967	-2.993	8.981e-03	0.213	-2.584	WHAMM	WAS protein homolog associated with actin, golgi membranes and microtubules	15	81275026	AI023634	123720	15q25.2	Hs.377360	5	actin binding cytoplasm ER-Golgi intermediate compartment Golgi apparatus membrane cytoplasmic vesicle membrane cytoplasmic vesicle
219584_at	1.454	5.503	2.993	8.988e-03	0.213	-2.584	PLA1A	phospholipase A1 member A	3	120799411	NM_015900	51365	3q13.13-q13.2	Hs.437451	11	extracellular region phosphatidylserine metabolic process phospholipase A1 activity lipid catabolic process hydrolase activity	Tropane, piperidine and pyridine alkaloid biosynthesis
225157_at	-0.619	9.347	-2.993	8.992e-03	0.213	-2.585	MLXIP	MLX interacting protein	12	121001142	AW245631	22877	12q24.31	Hs.437153	7	DNA binding nucleus cytoplasm mitochondrion mitochondrial outer membrane membrane transcription regulator activity regulation of transcription
200737_at	-0.836	8.965	-2.992	9.003e-03	0.213	-2.586	PGK1	phosphoglycerate kinase 1	X	77246321	NM_000291	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
215675_at	0.371	5.001	2.992	9.017e-03	0.213	-2.587	TEF	thyrotrophic embryonic factor	22	40093337, 40107908	AB051442	7008	22q13 22q13.2	Hs.181159	14	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity rhythmic process
1552899_at	0.570	4.863	2.991	9.019e-03	0.213	-2.587	RP4-662A9.2	hypothetical protein MGC34034	6	134183977	NM_153224	154089	6q23.2	Hs.126165	1
218041_x_at	-0.972	9.513	-2.991	9.023e-03	0.213	-2.588	SLC38A2	solute carrier family 38, member 2	12	-45038238	NM_018573	54407	12q	Hs.221847	20	plasma membrane ion transport sodium ion transport amino acid transport symporter activity integral to membrane sodium ion binding
226080_at	-0.907	8.766	-2.991	9.024e-03	0.213	-2.588	SSH2	slingshot homolog 2 (Drosophila)	17	-24977090	BE676214	85464	17q11.2	Hs.654754	11	actin binding protein tyrosine phosphatase activity cytoplasm cytoskeleton protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity actin cytoskeleton organization	Regulation of actin cytoskeleton
224755_at	-0.365	7.152	-2.991	9.025e-03	0.213	-2.588	TM9SF3	transmembrane 9 superfamily member 3	10	-98267856	BE621524	56889	10q24.1	Hs.500674	5	binding membrane integral to membrane
234195_at	0.283	5.146	2.991	9.029e-03	0.213	-2.588	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	8	23016378	AK026079	8794	8p22-p21	Hs.655801	43	transmembrane receptor activity plasma membrane integral to plasma membrane apoptosis signal transduction anchored to membrane	Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity
230484_at	0.237	5.199	2.991	9.031e-03	0.213	-2.589	CHDH	choline dehydrogenase	3	-53825427	AI741739	55349	3p21.1	Hs.126688	5	mitochondrion mitochondrial inner membrane alcohol metabolic process choline dehydrogenase activity FAD binding oxidation reduction	Glycine, serine and threonine metabolism
208826_x_at	-0.313	10.976	-2.991	9.034e-03	0.213	-2.589	HINT1	histidine triad nucleotide binding protein 1	5	-130522773, -130522773	U27143	3094	5q31.2	Hs.483305	26	protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity
238560_at	0.302	6.005	2.990	9.047e-03	0.213	-2.590	CALCOCO2	calcium binding and coiled-coil domain 2	17	44263370	AI684710	10241	17q21.32	Hs.514920	11	protein binding soluble fraction nucleus cytoplasm Golgi apparatus cytoskeleton viral reproduction response to interferon-gamma protein homodimerization activity perinuclear region of cytoplasm
226214_at	-0.489	8.802	-2.989	9.061e-03	0.213	-2.592	GDE1	glycerophosphodiester phosphodiesterase 1	16	-19420515	BE677894	51573	16p12-p11.2	Hs.512607	8	magnesium ion binding cytoplasm glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity glycerophosphoinositol glycerophosphodiesterase activity	Glycerophospholipid metabolism
227080_at	-0.537	5.638	-2.988	9.076e-03	0.214	-2.593	ZNF697	zinc finger protein 697	1	-119963522	AW003092	90874	1p12	Hs.381105 Hs.711175	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
201384_s_at	-0.468	8.599	-2.988	9.082e-03	0.214	-2.594	NBR1	neighbor of BRCA1 gene 1	17	38576023, 38576036, 38576771	NM_005899	4077	17q21.31	Hs.277721 Hs.373818 Hs.546264 Hs.708158	16	zinc ion binding metal ion binding
1562337_at	-0.656	4.318	-2.987	9.096e-03	0.214	-2.595	OR7D2	olfactory receptor, family 7, subfamily D, member 2	19	9157269	AK095468	162998	19p13.2	Hs.531755	4	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
226221_at	-0.571	6.172	-2.987	9.100e-03	0.214	-2.595	KIAA1432	KIAA1432	9	5619326, 5646582	AL138104	57589	9p24.1	Hs.211520	5	membrane integral to membrane
237044_s_at	0.442	5.463	2.987	9.101e-03	0.214	-2.596	C10orf41	chromosome 10 open reading frame 41	10	76831291, 76833519	AI480142	100131213	10q22.2	Hs.534598 Hs.599628	4
223000_s_at	0.498	6.332	2.986	9.117e-03	0.214	-2.597	F11R	F11 receptor	1	-159231624	AF172398	50848	1q21.2-q21.3	Hs.517293	63	protein binding plasma membrane cell-cell junction tight junction inflammatory response cell adhesion integral to membrane epithelial cell differentiation interspecies interaction between organisms	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
224355_s_at	0.555	5.409	2.986	9.123e-03	0.214	-2.598	MS4A8B	membrane-spanning 4-domains, subfamily A, member 8B	11	60223622	AF237905	83661	11q12.2	Hs.150878	5	receptor activity signal transduction membrane integral to membrane
1552848_a_at	0.425	4.164	2.985	9.136e-03	0.214	-2.599	PTCHD1	patched domain containing 1	X	23262905	NM_173495	139411	Xp22.11	Hs.319503	2	hedgehog receptor activity membrane integral to membrane
235848_x_at	-0.758	8.032	-2.985	9.145e-03	0.214	-2.600	ATL2	atlastin GTPase 2	2	-38375534	N35250	64225	2p22.2-p22.1	Hs.594950	8	nucleotide binding GTPase activity GTP binding membrane integral to membrane
201672_s_at	-0.418	9.677	-2.984	9.153e-03	0.214	-2.601	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	18	148482	NM_005151	9097	18p11.32	Hs.464416 Hs.707058	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity
227413_at	-0.465	5.646	-2.983	9.168e-03	0.214	-2.602	UBLCP1	ubiquitin-like domain containing CTD phosphatase 1	5	158622666	BF965546	134510	5q33.3	Hs.591733	7	phosphoprotein phosphatase activity nucleus hydrolase activity
226784_at	-0.366	5.732	-2.983	9.169e-03	0.214	-2.602	TWISTNB	TWIST neighbor	7	-19701609	AA121481	221830	7p21.1	Hs.353035	5	DNA-directed RNA polymerase activity nucleus nucleolus transcription
225113_at	-0.642	6.104	-2.983	9.173e-03	0.214	-2.603	AGPS	alkylglycerone phosphate synthase	2	177965716	BF688144	8540	2q31.2	Hs.516543	19	peroxisome peroxisomal membrane cytosol alkylglycerone-phosphate synthase activity lipid biosynthetic process membrane oxidoreductase activity transferase activity FAD binding	Ether lipid metabolism Metabolic pathways
209392_at	0.940	6.341	2.983	9.179e-03	0.214	-2.603	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	8	-120638500, -120638499	L35594	5168	8q24.1	Hs.190977	47	nucleic acid binding phosphodiesterase I activity nucleotide diphosphatase activity extracellular region plasma membrane integral to plasma membrane phosphate metabolic process cell motion chemotaxis G-protein coupled receptor protein signaling pathway transcription factor binding metabolic process lipid catabolic process hydrolase activity metal ion binding alkylglycerophosphoethanolamine phosphodiesterase activity	Ether lipid metabolism
205414_s_at	0.569	4.890	2.983	9.179e-03	0.214	-2.603	RICH2	Rho-type GTPase-activating protein RICH2	17	12633553	NM_014859	9912	17p12	Hs.499758	7	GTPase activator activity protein binding intracellular cytoplasm signal transduction
208458_at	0.331	5.337	2.982	9.196e-03	0.214	-2.605	SCNN1D	sodium channel, nonvoltage-gated 1, delta	1	1207351, 1207438	NM_002978	6339	1p36.3-p36.2	Hs.512681	16	ion channel activity ion transport sodium ion transport amiloride-sensitive sodium channel activity membrane integral to membrane sodium ion binding response to stimulus sensory perception of taste
222405_at	0.285	6.985	2.982	9.203e-03	0.214	-2.606	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	15	63609879	AL573951	51495	15q22.2	Hs.512973	13	molecular_function GTPase activator activity protein binding cellular_component I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity small GTPase mediated signal transduction Rho protein signal transduction membrane integral to membrane Rac protein signal transduction
204725_s_at	-0.510	7.380	-2.982	9.203e-03	0.214	-2.606	NCK1	NCK adaptor protein 1	3	138063762	NM_006153	4690	3q21	Hs.477693	110	receptor binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal complex assembly cytoskeletal adaptor activity vesicle membrane cell migration protein domain specific binding lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
223355_at	-0.294	4.114	-2.981	9.205e-03	0.214	-2.606	ALG1	asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)	16	5061810	BC004402	56052	16p13.3	Hs.592086	9	chitobiosyldiphosphodolichol beta-mannosyltransferase activity endoplasmic reticulum protein amino acid glycosylation biosynthetic process lipopolysaccharide biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups	N-Glycan biosynthesis Metabolic pathways
238462_at	-0.508	2.700	-2.981	9.211e-03	0.214	-2.606	UBASH3B	ubiquitin associated and SH3 domain containing, B	11	122031607	AI418293	84959	11q24.1	Hs.444075	15	nucleus cytoplasm
210867_at	-0.464	5.238	-2.980	9.225e-03	0.215	-2.608	CNOT4	CCR4-NOT transcription complex, subunit 4	7	-134723303, -134697088	AF180475	4850	7q22-qter	Hs.490224	7	nucleotide binding RNA binding protein binding nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process regulation of transcription metal ion binding	RNA degradation
200671_s_at	-0.483	5.770	-2.979	9.253e-03	0.215	-2.611	SPTBN1	spectrin, beta, non-erythrocytic 1	2	54536957, 54639034	N92501	6711	2p21	Hs.503178 Hs.705692	46	actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping
221030_s_at	-0.650	5.403	-2.979	9.256e-03	0.215	-2.611	ARHGAP24	Rho GTPase activating protein 24	4	86615307, 86918874, 87070449	NM_031305	83478	4q21.23-q21.3	Hs.444229	14	angiogenesis GTPase activator activity protein binding intracellular cytoplasm cytoskeleton adherens junction focal adhesion signal transduction multicellular organismal development cell junction cell differentiation cell projection
201574_at	-0.454	8.905	-2.978	9.269e-03	0.215	-2.612	ETF1	eukaryotic translation termination factor 1	5	-137869682	NM_004730	2107	5q31.1	Hs.483494	32	RNA binding protein binding cytoplasm regulation of translational termination protein amino acid methylation translation release factor activity, codon specific ribosome binding
232349_x_at	-0.618	9.489	-2.977	9.280e-03	0.215	-2.613	DCAF6	DDB1 and CUL4 associated factor 6	1	166172531	BF671187	55827	1q24.2	Hs.435741	10	nucleus ligand-dependent nuclear receptor transcription coactivator activity
211151_x_at	0.335	4.464	2.977	9.285e-03	0.215	-2.614	GH1	growth hormone 1	17	-59348294	AF185611	2688	17q24.2	Hs.655229	227	positive regulation of receptor internalization growth hormone receptor binding prolactin receptor binding protein binding extracellular region extracellular space growth factor activity positive regulation of activation of JAK2 kinase activity positive regulation of phosphoinositide 3-kinase cascade glucose transport response to estradiol stimulus positive regulation of multicellular organism growth positive regulation of multicellular organism growth positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein positive regulation of MAP kinase activity positive regulation of insulin-like growth factor receptor signaling pathway positive regulation of JAK-STAT cascade positive regulation of peptidyl-tyrosine phosphorylation growth hormone receptor signaling pathway growth hormone activity	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Jak-STAT signaling pathway
1562511_at	-0.272	3.483	-2.977	9.293e-03	0.216	-2.615	LYST	lysosomal trafficking regulator	1	-233890968	AL833100	1130	1q42.1-q42.2	Hs.532411	23	protein binding cytoplasm protein transport microtubule cytoskeleton leukocyte chemotaxis melanosome organization endosome to lysosome transport via multivesicular body sorting pathway mast cell secretory granule organization natural killer cell mediated cytotoxicity defense response to bacterium defense response to protozoan pigmentation defense response to virus
239218_at	0.510	3.355	2.977	9.295e-03	0.216	-2.615	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	7	-31795771	AI800515	5137	7p14.3	Hs.655694	10	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity	Purine metabolism Calcium signaling pathway Olfactory transduction
221932_s_at	0.419	10.590	2.976	9.302e-03	0.216	-2.615	GLRX5	glutaredoxin 5	14	95071075	AA133341	51218	14q32.13	Hs.532683 Hs.719204	5	mitochondrion electron carrier activity protein disulfide oxidoreductase activity cell redox homeostasis
205148_s_at	-0.707	6.344	-2.976	9.314e-03	0.216	-2.617	CLCN4	chloride channel 4	X	10084984	AA071195	1183	Xp22.3	Hs.495674	17	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding
216125_s_at	-0.918	5.549	-2.975	9.321e-03	0.216	-2.617	RANBP9	RAN binding protein 9	6	-13729708	AF064606	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
230359_at	0.301	5.518	2.975	9.324e-03	0.216	-2.618	KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	10	134823960	N45097	85442	10q26.3	Hs.530685	3	molecular_function guanyl-nucleotide exchange factor activity cellular_component intracellular biological_process regulation of small GTPase mediated signal transduction
218813_s_at	-0.493	5.345	-2.975	9.329e-03	0.216	-2.618	SH3GLB2	SH3-domain GRB2-like endophilin B2	9	-130810133	NM_020145	56904	9q34	Hs.460238	13	protein binding nucleus nucleolus cytoplasm	Endocytosis
205210_at	-0.298	5.527	-2.974	9.337e-03	0.216	-2.619	TGFBRAP1	transforming growth factor, beta receptor associated protein 1	2	-105249973	NM_004257	9392	2q12.1	Hs.446350	7	transforming growth factor beta receptor binding cytoplasm signal transduction transforming growth factor beta receptor signaling pathway membrane regulation of transcription SMAD binding
202811_at	-0.415	8.074	-2.974	9.339e-03	0.216	-2.619	STAMBP	STAM binding protein	2	73909593, 73909634, 73909654	NM_006463	10617	2p13.1	Hs.469018 Hs.657598	28	ubiquitin thiolesterase activity protein binding nucleus cytoplasm early endosome anti-apoptosis JAK-STAT cascade peptidase activity metallopeptidase activity zinc ion binding positive regulation of cell proliferation membrane modification-dependent protein catabolic process metal ion binding	Endocytosis
200812_at	-0.322	9.517	-2.974	9.347e-03	0.216	-2.620	CCT7	chaperonin containing TCP1, subunit 7 (eta)	2	73314912	NM_006429	10574	2p13.2	Hs.368149	18	nucleotide binding ATP binding cytoplasm protein folding unfolded protein binding
220816_at	0.388	5.461	2.973	9.357e-03	0.216	-2.621	LPAR3	lysophosphatidic acid receptor 3	1	-85051673	NM_012152	23566	1p22.3	Hs.674915	19	activation of MAPK activity lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger elevation of cytosolic calcium ion concentration synaptic transmission lipid binding bleb formation positive regulation of MAPKKK cascade	Neuroactive ligand-receptor interaction
201339_s_at	-0.384	8.737	-2.973	9.357e-03	0.216	-2.621	SCP2	sterol carrier protein 2	1	53165535, 53165535, 53253197	NM_002979	6342	1p32	Hs.476365 Hs.709369	36	sterol carrier activity protein binding cytoplasm mitochondrion peroxisome steroid biosynthetic process lipid transport metabolic process lipid binding oxidoreductase activity transferase activity propanoyl-CoA C-acyltransferase activity	Primary bile acid biosynthesis Metabolic pathways PPAR signaling pathway
230143_at	0.675	5.047	2.973	9.360e-03	0.216	-2.621	RNF165	ring finger protein 165	18	42168184	BF433220	494470	18q21.1	Hs.501114	4	protein binding zinc ion binding metal ion binding
201361_at	-0.347	7.562	-2.973	9.361e-03	0.216	-2.621	TMEM109	transmembrane protein 109	11	60437946	NM_024092	79073	11q12.2	Hs.13662	5	molecular_function cellular_component nucleus nucleolus cytoplasm biological_process membrane integral to membrane sarcoplasmic reticulum nuclear membrane
235344_at	-0.724	6.993	-2.973	9.363e-03	0.216	-2.621	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	BG288054	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
209311_at	-0.392	6.931	-2.973	9.368e-03	0.216	-2.622	BCL2L2	BCL2-like 2	14	22845851	D87461	599	14q11.2-q12	Hs.410026	31	protein binding mitochondrion cytosol anti-apoptosis spermatogenesis membrane mitochondrial membrane regulation of apoptosis Sertoli cell proliferation
200914_x_at	-0.583	10.569	-2.973	9.371e-03	0.216	-2.622	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	BF589024	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
201066_at	0.353	11.243	2.972	9.378e-03	0.216	-2.623	CYC1	cytochrome c-1	8	145221947	NM_001916	1537	8q24.3	Hs.289271	23	mitochondrion mitochondrial inner membrane transport membrane integral to membrane heme binding electron transport chain electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity metal ion binding respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
219839_x_at	0.301	4.571	2.972	9.379e-03	0.216	-2.623	TCL6	T-cell leukemia/lymphoma 6	14	95187267, 95187267, 95199345, 95199345, 95199345	NM_012468	27004	14q32.1	Hs.510368	4	molecular_function cellular_component biological_process
205391_x_at	0.491	11.171	2.972	9.383e-03	0.216	-2.623	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	M28880	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
224394_at	-0.473	4.431	-2.971	9.397e-03	0.216	-2.625	RNF7	ring finger protein 7	3	142939740	AF312226	9616	3q22-q24	Hs.134623	25	copper ion binding protein binding nucleus cytoplasm anti-apoptosis redox signal response zinc ion binding induction of apoptosis by oxidative stress NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation metal ion binding	Ubiquitin mediated proteolysis
200009_at	-0.476	9.430	-2.971	9.411e-03	0.216	-2.626	GDI2	GDP dissociation inhibitor 2	10	-5847191	NM_001494	2665	10p15	Hs.299055	16	Rab GDP-dissociation inhibitor activity GTPase activator activity cytoplasm signal transduction cell surface protein transport membrane regulation of GTPase activity
225182_at	-0.683	8.054	-2.970	9.415e-03	0.216	-2.626	TMEM50B	transmembrane protein 50B	21	-33743317	AL355685	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
208055_s_at	-0.317	3.864	-2.970	9.416e-03	0.216	-2.626	HERC4	hect domain and RLD 4	10	-69351661	NM_015601	26091	10q21.3	Hs.51891	7	intracellular cytoplasm cytosol protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
208557_at	0.466	5.361	2.970	9.421e-03	0.216	-2.627	HOXA6	homeobox A6	7	-27151640	NM_024014	3203	7p15-p14	Hs.679517	12	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation sequence-specific DNA binding embryonic skeletal system morphogenesis
202539_s_at	-0.594	5.336	-2.970	9.423e-03	0.216	-2.627	HMGCR	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	5	74668748	AL518627	3156	5q13.3-q14	Hs.643495 Hs.698445 Hs.713530	72	hydroxymethylglutaryl-CoA reductase (NADPH) activity peroxisome endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane cholesterol biosynthetic process isoprenoid biosynthetic process germ cell migration gonad development coenzyme A metabolic process membrane integral to membrane oxidoreductase activity NADP or NADPH binding oxidation reduction	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
235815_at	0.311	3.830	2.969	9.433e-03	0.216	-2.628	TSHZ2	teashirt zinc finger homeobox 2	20	51022283	BE222470	128553	20q13.2	Hs.271605 Hs.473117 Hs.649877	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding
228067_at	0.577	5.292	2.969	9.437e-03	0.216	-2.628	C2orf55	chromosome 2 open reading frame 55	2	-98776740	AW249666	343990	2q11.2	Hs.469398	1
1560514_at	0.330	3.903	2.969	9.440e-03	0.216	-2.629	LOC285205	hypothetical LOC285205	3	109084741	BC039517	285205	3q13.12	Hs.134882	2
209503_s_at	-0.378	9.753	-2.969	9.441e-03	0.216	-2.629	PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	17	59258541	AF035309	5705	17q23-q25	Hs.79387	71	nucleotide binding proteasome complex transcription cofactor activity ATP binding nucleus nucleolus cytoplasm cytosol transcription from RNA polymerase II promoter hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process thyrotropin-releasing hormone receptor binding negative regulation of programmed cell death positive regulation of gene-specific transcription negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
1557821_at	0.254	3.139	2.969	9.450e-03	0.216	-2.630	LOC283547	hypothetical protein LOC283547	14		BC035119	283547	14q21.1	Hs.675941	1
201238_s_at	-0.646	10.394	-2.968	9.457e-03	0.216	-2.630	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	7	116289798	BC005338	830	7q31.2-q31.3	Hs.446123	14	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
211086_x_at	0.270	3.870	2.968	9.462e-03	0.216	-2.631	NEK1	NIMA (never in mitosis gene a)-related kinase 1	4	-170551003	Z25431	4750	4q33	Hs.481181	11	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division
226106_at	-0.547	8.884	-2.968	9.462e-03	0.216	-2.631	RNF141	ring finger protein 141	11	-10489800	AI307808	50862	11p15.4	Hs.44685	7	DNA binding protein binding regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207862_at	0.303	3.791	2.968	9.464e-03	0.216	-2.631	UPK2	uroplakin 2	11	118332235	NM_006760	7379	11q23	Hs.710330	14	plasma membrane integral to plasma membrane multicellular organismal development membrane organization integral to endoplasmic reticulum membrane epithelial cell differentiation
209905_at	0.538	7.543	2.968	9.469e-03	0.216	-2.632	HOXA9	homeobox A9	7	-27168581	AI246769	3205	7p15-p14	Hs.659350	63	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity sequence-specific DNA binding
211548_s_at	-0.581	5.023	-2.967	9.471e-03	0.216	-2.632	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	4	-175647902, -175647902	J05594	3248	4q34-q35	Hs.596913	47	prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction
1555976_s_at	-0.979	6.343	-2.967	9.486e-03	0.216	-2.633	MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	18	3237527	BU676221	10627	18p11.31	Hs.190086	9	motor activity calcium ion binding protein binding myosin complex	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
217148_x_at	0.696	5.646	2.967	9.489e-03	0.216	-2.633	IGL@	immunoglobulin lambda locus	22		AJ249377	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
1559293_x_at	0.337	3.805	2.966	9.498e-03	0.216	-2.634	NCRNA00032	non-protein coding RNA 32	9	-27235683	AF507950	158035	9p21	Hs.201554	1
218455_at	0.477	6.681	2.966	9.500e-03	0.216	-2.635	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	20	-33720024	NM_021100	9054	20q11.22	Hs.194692	14	protein binding nucleus cytoplasm mitochondrion mitochondrial matrix cytosol protein complex assembly cysteine metabolic process Mo-molybdopterin cofactor biosynthetic process metabolic process transferase activity iron incorporation into metallo-sulfur cluster pyridoxal phosphate binding cysteine desulfurase activity protein homodimerization activity	Thiamine metabolism
206158_s_at	-0.449	11.893	-2.965	9.519e-03	0.217	-2.636	CNBP	CCHC-type zinc finger, nucleic acid binding protein	3	-130369347	NM_003418	7555	3q21	Hs.518249	24	transcription factor activity protein binding cytoplasm endoplasmic reticulum regulation of transcription, DNA-dependent cholesterol biosynthetic process zinc ion binding metal ion binding
208373_s_at	0.325	5.275	2.965	9.522e-03	0.217	-2.637	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	11	72653217, 72658586, 72660894	NM_004154	5031	11q13.5	Hs.16362	23	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger transepithelial chloride transport purinergic nucleotide receptor activity, G-protein coupled UDP-activated nucleotide receptor activity	Neuroactive ligand-receptor interaction
218744_s_at	-0.604	8.410	-2.965	9.523e-03	0.217	-2.637	PACSIN3	protein kinase C and casein kinase substrate in neurons 3	11	-47155656	NM_016223	29763	11p12-p11.12	Hs.334639	14	cytoplasm plasma membrane cytoskeletal protein binding negative regulation of endocytosis positive regulation of membrane protein ectodomain proteolysis
228748_at	-0.709	6.728	-2.964	9.549e-03	0.217	-2.639	CD59	CD59 molecule, complement regulatory protein	11	-33681131, -33681131, -33681131	AI653117	966	11p13	Hs.278573 Hs.709466 Hs.710641	107	protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane	Complement and coagulation cascades Hematopoietic cell lineage
37170_at	-0.449	3.934	-2.963	9.554e-03	0.217	-2.640	BMP2K	BMP2 inducible kinase	4	79916555, 79916555	AB015331	55589	4q21.21	Hs.146551	11	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity
203008_x_at	-0.476	7.997	-2.962	9.576e-03	0.217	-2.642	TXNDC9	thioredoxin domain containing 9	2	-99301918	NM_005783	10190	2q11.2	Hs.536122	8	protein binding cellular_component biological_process
219036_at	-0.377	6.139	-2.962	9.577e-03	0.217	-2.642	CEP70	centrosomal protein 70kDa	3	-139695876	NM_024491	80321	3q22-q23	Hs.531962	9	protein binding centrosome
205437_at	0.579	5.822	2.962	9.578e-03	0.217	-2.642	ZNF211	zinc finger protein 211	19	62836346	NM_006385	10520	19q13.4	Hs.590977	4	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203885_at	-0.592	8.739	-2.962	9.580e-03	0.217	-2.642	RAB21	RAB21, member RAS oncogene family	12	70434924	NM_014999	23011	12q21.1	Hs.524590	12	Golgi membrane nucleotide binding protein binding GTP binding endosome endoplasmic reticulum Golgi apparatus small GTPase mediated signal transduction protein transport membrane cytoplasmic vesicle membrane cytoplasmic vesicle early endosome membrane
233878_s_at	-0.490	5.234	-2.962	9.582e-03	0.217	-2.642	XRN2	5'-3' exoribonuclease 2	20	21231941	BE536170	22803	20p11.2-p11.1	Hs.255932	18	DNA catabolic process, exonucleolytic nucleic acid binding 5'-3' exoribonuclease activity protein binding intracellular nucleus nucleolus transcription termination mRNA processing RNA catabolic process spermatogenesis zinc ion binding cell growth hydrolase activity regulation of transcription metal ion binding	RNA degradation
224922_at	-0.403	5.925	-2.962	9.587e-03	0.217	-2.643	CSNK2A2	casein kinase 2, alpha prime polypeptide	16	-56749312	AI022089	1459	16q21	Hs.82201	143	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity protein N-terminus binding regulation of cell cycle	Wnt signaling pathway Adherens junction Tight junction
218029_at	0.314	6.302	2.961	9.601e-03	0.217	-2.644	FAM65A	family with sequence similarity 65, member A	16	66120254	NM_024519	79567	16q22.1	Hs.152717	5	binding
1558028_x_at	-1.059	5.884	-2.961	9.603e-03	0.217	-2.644	LOC647979	hypothetical LOC647979	20	-34096955	BI857154	647979	20q11.23	Hs.649310 Hs.718413	2
204779_s_at	0.521	4.610	2.961	9.603e-03	0.217	-2.644	HOXB7	homeobox B7	17	-44039593	NM_004502	3217	17q21.3	Hs.436181	39	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation myeloid cell differentiation sequence-specific DNA binding embryonic skeletal system morphogenesis
210251_s_at	-0.685	5.534	-2.960	9.609e-03	0.217	-2.645	RUFY3	RUN and FYVE domain containing 3	4	71789517, 71806559, 71806559	AF112221	22902	4q13.3	Hs.713172	8	multicellular organismal development nervous system development cell differentiation filopodium growth cone negative regulation of axonogenesis
231666_at	-0.771	5.277	-2.960	9.623e-03	0.217	-2.646	PAX3	paired box 3	2	-222866592, -222774675, -222772850	AA194168	5077	2q35 2q35-q37	Hs.42146	103	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter apoptosis multicellular organismal development sensory perception of sound organ morphogenesis sequence-specific DNA binding
242224_at	-0.340	3.122	-2.960	9.625e-03	0.217	-2.646	GPATCH2	G patch domain containing 2	1	-215670456	R40111	55105	1q41	Hs.420757	6	nucleic acid binding intracellular
228346_at	0.671	6.290	2.959	9.632e-03	0.217	-2.647	ZNF844	zinc finger protein 844	19	12036545	H47630	284391	19p13.2	Hs.646391	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222399_s_at	-0.625	7.381	-2.959	9.636e-03	0.217	-2.647	TM9SF3	transmembrane 9 superfamily member 3	10	-98267856	BG104571	56889	10q24.1	Hs.500674	5	binding membrane integral to membrane
241512_at	0.254	4.463	2.959	9.637e-03	0.217	-2.647	SPATC1	spermatogenesis and centriole associated 1	8	145158569	AI026805	375686	8q24.3	Hs.97726	3	cytoplasm centrosome
214876_s_at	-0.550	4.951	-2.959	9.637e-03	0.217	-2.647	TUBGCP5	tubulin, gamma complex associated protein 5	15	20384835, 20384835	AI628925	114791	15q11.2	Hs.533898	9	spindle pole centrosome microtubule microtubule nucleation microtubule binding gamma-tubulin ring complex
209234_at	-1.312	7.572	-2.959	9.643e-03	0.217	-2.648	KIF1B	kinesin family member 1B	1	10193350, 10193350	BF939474	23095	1p36.2	Hs.97858	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle
226992_at	0.675	5.455	2.959	9.646e-03	0.217	-2.648	NOSTRIN	nitric oxide synthase trafficker	2	169367352, 169367398	AK002203	115677	2q24.3-q31.1	Hs.189780	9	protein binding cytoplasm cytoskeleton plasma membrane plasma membrane endocytosis cytoplasmic vesicle
219640_at	0.356	7.546	2.958	9.650e-03	0.217	-2.649	CLDN15	claudin 15	7	-100662093	NM_014343	24146	7q11.22	Hs.38738	11	structural molecule activity plasma membrane tight junction integral to membrane calcium-independent cell-cell adhesion cell junction identical protein binding	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration
225911_at	1.056	4.528	2.958	9.660e-03	0.217	-2.650	NPNT	nephronectin	4	107036053	AL138410	255743	4q24	Hs.518921	5	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development membrane cell differentiation
203399_x_at	0.333	3.589	2.958	9.665e-03	0.217	-2.650	PSG3	pregnancy specific beta-1-glycoprotein 3	19	-47917633	NM_021016	5671	19q13.2	Hs.654413	13	extracellular region defense response female pregnancy
210652_s_at	0.735	4.608	2.957	9.672e-03	0.217	-2.651	TTC39A	tetratricopeptide repeat domain 39A	1	-51525518, -51525518	BC004399	22996	1p32.3	Hs.112949	3	binding cellular_component biological_process
217609_at	0.396	4.405	2.957	9.674e-03	0.217	-2.651	LRRC23	leucine rich repeat containing 23	12	6884157	BG420747	10233	12p13	Hs.155586	10	molecular_function protein binding cellular_component biological_process
1554015_a_at	-0.461	4.832	-2.957	9.676e-03	0.217	-2.651	CHD2	chromodomain helicase DNA binding protein 2	15	91244554, 91244554	BC007347	1106	15q26	Hs.220864	9	nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter hydrolase activity
208731_at	-0.653	9.818	-2.956	9.690e-03	0.217	-2.653	RAB2A	RAB2A, member RAS oncogene family	8	61592112	AU158062	5862	8q12.1	Hs.369017	19	nucleotide binding GTPase activity GTP binding endoplasmic reticulum Golgi apparatus ER to Golgi vesicle-mediated transport small GTPase mediated signal transduction protein transport membrane vesicle-mediated transport melanosome
213599_at	-0.826	6.367	-2.956	9.699e-03	0.217	-2.653	OIP5	Opa interacting protein 5	15	-39388757	BE045993	11339	15q15.1	Hs.661645	6	chromosome, centromeric region chromatin protein binding cellular_component nucleus cell cycle mitosis cell communication chromocenter Cajal body cell division
227862_at	0.557	5.362	2.956	9.701e-03	0.217	-2.653	TRNP1	TMF1-regulated nuclear protein 1	1	27192781	AA037766	388610	1p36.11	Hs.355747	2	nucleus cell cycle
211327_x_at	0.360	4.844	2.955	9.714e-03	0.217	-2.655	HFE	hemochromatosis	6	26195487	AF149804	3077	6p21.3	Hs.233325	592	antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome
235180_at	-0.273	2.966	-2.955	9.718e-03	0.217	-2.655	STYX	serine/threonine/tyrosine interacting protein	14	52266632	AI492892	6815		Hs.364980	8	protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
208815_x_at	-0.436	7.873	-2.955	9.726e-03	0.217	-2.656	HSPA4	heat shock 70kDa protein 4	5	132415560	AB023420	3308	5q31.1-q31.2	Hs.90093	108	nucleotide binding ATP binding nucleus cytoplasm response to unfolded protein cellular chaperone-mediated protein complex assembly mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation
1553600_at	0.307	4.617	2.954	9.726e-03	0.217	-2.656	TMIE	transmembrane inner ear	3	46717826	NM_147196	259236	3p21	Hs.185777	10	sensory perception of sound membrane integral to membrane inner ear morphogenesis
210210_at	0.293	6.120	2.954	9.730e-03	0.217	-2.656	MPZL1	myelin protein zero-like 1	1	165957810	AF181660	9019	1q24.2	Hs.493919 Hs.603116	19	structural molecule activity protein binding integral to plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling membrane	Cell adhesion molecules (CAMs)
226921_at	-0.667	8.092	-2.954	9.733e-03	0.217	-2.657	UBR1	ubiquitin protein ligase E3 component n-recognin 1	15	-41022389	AV715153	197131	15q13	Hs.591121	21	ubiquitin ligase complex proteasome complex ubiquitin-protein ligase activity protein binding cytoplasm cytosol ubiquitin-dependent protein catabolic process zinc ion binding ligase activity protein catabolic process metal ion binding
201305_x_at	-0.592	8.368	-2.954	9.735e-03	0.217	-2.657	ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	9	99785309	AV712577	10541	9q22.32	Hs.715547	16	protein binding nucleus
1558251_a_at	0.361	3.079	2.953	9.748e-03	0.217	-2.658	ZNF587	zinc finger protein 587	19	63053080	AK055448	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209066_x_at	0.290	11.943	2.953	9.750e-03	0.217	-2.658	UQCRB	ubiquinol-cytochrome c reductase binding protein	8	-97308479	M26700	7381	8q22	Hs.131255	10	mitochondrion mitochondrial respiratory chain oxidative phosphorylation mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity aerobic respiration membrane electron transport chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
207164_s_at	-0.559	3.944	-2.953	9.765e-03	0.217	-2.659	ZNF238	zinc finger protein 238	1	242281183, 242283204	NM_006352	10472	1q44-qter	Hs.69997	11	negative regulation of transcription from RNA polymerase II promoter nuclear chromosome transcription factor activity protein binding intracellular nucleus transport zinc ion binding regulation of transcription metal ion binding
201222_s_at	-0.517	8.610	-2.952	9.766e-03	0.217	-2.660	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	AL527365	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
222439_s_at	-0.694	7.555	-2.952	9.769e-03	0.217	-2.660	THRAP3	thyroid hormone receptor associated protein 3	1	36462603	BE967048	9967	1p34.3	Hs.160211	21	nucleotide binding receptor activity protein binding ATP binding nucleus nucleolus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
206050_s_at	-0.390	7.701	-2.952	9.769e-03	0.217	-2.660	RNH1	ribonuclease/angiogenin inhibitor 1	11	-484511, -484511	NM_002939	6050	11p15.5	Hs.530687	23	protein binding cytoplasm mRNA catabolic process ribonuclease inhibitor activity angiogenin-PRI complex regulation of angiogenesis
212266_s_at	-0.382	8.004	-2.952	9.784e-03	0.218	-2.661	SFRS5	splicing factor, arginine/serine-rich 5	14	69303581, 69303586	AW084582	6430	14q24	Hs.632326	28	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA splice site selection RNA splicing RS domain binding
200698_at	-0.400	6.621	-2.951	9.789e-03	0.218	-2.662	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	7	-6467236	AL542253	11014	7p22.1	Hs.654552 Hs.705873	12	receptor activity KDEL sequence binding protein binding endoplasmic reticulum Golgi apparatus protein retention in ER lumen intracellular protein transport membrane integral to membrane vesicle-mediated transport	Vibrio cholerae infection
212251_at	-0.517	9.406	-2.951	9.794e-03	0.218	-2.662	MTDH	metadherin	8	98725582	AI972475	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
214719_at	-0.319	6.682	-2.951	9.803e-03	0.218	-2.663	SLC46A3	solute carrier family 46, member 3	13	-28172219	AK026720	283537	13q12.3	Hs.117167	5	membrane integral to membrane
218311_at	-0.566	7.417	-2.950	9.818e-03	0.218	-2.664	MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	2	-39329925	NM_003618	8491	2p22.1	Hs.655750	7	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade transferase activity	MAPK signaling pathway
1552785_at	0.392	2.742	2.950	9.821e-03	0.218	-2.665	ZNF781	zinc finger protein 781	19	-42850489	NM_152605	163115	19q13.12	Hs.116622	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
205843_x_at	0.417	8.314	2.949	9.827e-03	0.218	-2.665	CRAT	carnitine acetyltransferase	9	-130896895, -130896893	NM_000755	1384	9q34.1	Hs.12068	10	carnitine O-acetyltransferase activity mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum lipid metabolic process fatty acid metabolic process transport acyltransferase activity energy derivation by oxidation of organic compounds membrane transferase activity
225302_at	-0.471	7.086	-2.948	9.849e-03	0.218	-2.667	TMX3	thioredoxin-related transmembrane protein 3	18	-64491904	BE503286	54495	18q22	Hs.440534	11	protein disulfide isomerase activity endoplasmic reticulum membrane integral to membrane isomerase activity cell redox homeostasis
227874_at	0.534	7.601	2.948	9.855e-03	0.218	-2.668	EMCN	endomucin	4	-101535522	AI635774	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
216348_at	0.320	7.452	2.948	9.863e-03	0.219	-2.669	RPS17P5	ribosomal protein S17 pseudogene 5	6		AL049693	442216	6p12.3		2
240770_at	0.795	2.734	2.947	9.867e-03	0.219	-2.669	TMEM171	transmembrane protein 171	5	72452143	AW058459	134285	5q13.2	Hs.162246	5	membrane integral to membrane
211015_s_at	-0.660	6.698	-2.947	9.870e-03	0.219	-2.669	HSPA4	heat shock 70kDa protein 4	5	132415560	L12723	3308	5q31.1-q31.2	Hs.90093	108	nucleotide binding ATP binding nucleus cytoplasm response to unfolded protein cellular chaperone-mediated protein complex assembly mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation
226254_s_at	-0.464	7.197	-2.947	9.876e-03	0.219	-2.670	KIAA1430	KIAA1430	4	-186317812	AI912523	57587	4q35.1	Hs.535734	3
201881_s_at	-0.574	7.217	-2.946	9.901e-03	0.219	-2.672	ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	15	70553720	NM_005744	25820	15q24	Hs.268787	11	ubiquitin ligase complex protein binding cytoplasm ubiquitin-dependent protein catabolic process zinc ion binding small conjugating protein ligase activity metal ion binding
206016_at	-0.602	5.393	-2.946	9.902e-03	0.219	-2.672	CCDC22	coiled-coil domain containing 22	X	48978884	NM_014008	28952	Xp11.23	Hs.247700 Hs.26333	6	molecular_function cellular_component biological_process
200042_at	-0.380	7.938	-2.945	9.907e-03	0.219	-2.673	C22orf28	chromosome 22 open reading frame 28	22	-31113561	NM_014306	51493	22q12	Hs.474643	10	cellular_component cell-matrix adhesion vinculin binding substrate adhesion-dependent cell spreading
226234_at	-0.346	3.807	-2.945	9.909e-03	0.219	-2.673	GDF11	growth differentiation factor 11	12	54423330	D80983	10220	12q13.2	Hs.600883	10	skeletal system development ureteric bud development cytokine activity protein binding extracellular region extracellular space nervous system development mesoderm development growth factor activity negative regulation of cell proliferation organ morphogenesis spinal cord anterior/posterior patterning pancreas development growth negative regulation of cell differentiation cell maturation camera-type eye morphogenesis
209486_at	-0.411	7.581	-2.945	9.911e-03	0.219	-2.673	UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	4	71773059	BC004546	57050	4q13.3	Hs.322901	15	molecular_function protein binding nucleus nucleolus multicellular organismal development brain development gene silencing chromatin modification
225140_at	-0.430	3.678	-2.945	9.918e-03	0.219	-2.674	KLF3	Kruppel-like factor 3 (basic)	4	38342184	BF438116	51274	4p14	Hs.298658	12	transcription factor activity intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
239924_at	0.244	3.275	2.944	9.929e-03	0.219	-2.675	LOC91316	glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene	22	-22310675	AA629699	91316	22q11.23	Hs.148656	4
202765_s_at	-0.928	5.808	-2.944	9.931e-03	0.219	-2.675	FBN1	fibrillin 1	15	-46487796	AI264196	2200	15q21.1	Hs.591133	179	skeletal system development microfibril extracellular matrix structural constituent extracellular matrix structural constituent calcium ion binding calcium ion binding protein binding extracellular region basement membrane extracellular space heart development
209512_at	0.773	8.671	2.944	9.945e-03	0.219	-2.676	HSDL2	hydroxysteroid dehydrogenase like 2	9	114182171	BC004331	84263	9q32	Hs.59486	6	binding sterol carrier activity oxidoreductase activity oxidation reduction
202813_at	0.320	7.372	2.943	9.958e-03	0.219	-2.677	TARBP1	TAR (HIV-1) RNA binding protein 1	1	-232593681	NM_005646	6894	1q42.3	Hs.498115	12	RNA binding binding nucleus regulation of transcription from RNA polymerase II promoter RNA processing RNA methyltransferase activity transferase activity
224899_s_at	-0.408	8.102	-2.943	9.959e-03	0.219	-2.677	MAGT1	magnesium transporter 1	X	-76968519	BG292405	84061	Xq21.1	Hs.323562 Hs.710189	14	dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum oligosaccharyltransferase complex membrane integral to membrane protein amino acid N-linked glycosylation via asparagine
204736_s_at	-0.373	4.947	-2.942	9.970e-03	0.219	-2.678	CSPG4	chondroitin sulfate proteoglycan 4	15	-73753717	NM_001897	1464	15q24.2	Hs.513044	34	angiogenesis signal transducer activity receptor signaling protein tyrosine phosphatase signaling protein activity protein binding plasma membrane integral to plasma membrane signal transduction multicellular organismal development receptor signaling protein tyrosine kinase signaling protein activity cell surface cell differentiation cell projection tissue remodeling
221764_at	-0.405	5.979	-2.942	9.986e-03	0.220	-2.680	C19orf22	chromosome 19 open reading frame 22	19	-847502	AL574186	91300	19p13.3	Hs.557655	2	nucleic acid binding nucleus
228793_at	-0.463	5.823	-2.942	9.986e-03	0.220	-2.680	JMJD1C	jumonji domain containing 1C	10	-64596993, -64596993	BF002296	221037	10q21.3	Hs.413416	10	iron ion binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding thyroid hormone receptor binding oxidation reduction
219811_at	0.344	6.849	2.941	9.999e-03	0.220	-2.681	DGCR8	DiGeorge syndrome critical region gene 8	22	18447833	NM_022720	54487	22q11.2	Hs.643452 Hs.713579	21	double-stranded RNA binding protein binding intracellular nucleus cytoplasm primary microRNA processing
214460_at	0.388	4.817	2.940	1.001e-02	0.220	-2.682	LSAMP	limbic system-associated membrane protein	3	-117011831	NM_002338	4045	3q13.2-q21	Hs.657246	8	protein binding plasma membrane cell adhesion nervous system development anchored to membrane
225542_at	-0.285	5.045	-2.940	1.002e-02	0.220	-2.683	ACAP3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	1	-1217626	AB051503	116983		Hs.535257	6	ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding	Endocytosis
201466_s_at	-0.692	7.438	-2.940	1.002e-02	0.220	-2.683	JUN	jun oncogene	1	-59019050	NM_002228	3725	1p32-p31	Hs.714791	443	nuclear chromosome transcription factor activity RNA polymerase II transcription factor activity Rho GTPase activator activity nucleus transcription factor complex cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation transcription factor binding negative regulation of cell proliferation cellular process promoter binding negative regulation of protein amino acid autophosphorylation leading edge cell differentiation response to drug positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein dimerization activity regulation of cell cycle SMAD protein signal transduction R-SMAD binding	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma
208064_s_at	0.396	3.381	2.940	1.002e-02	0.220	-2.683	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	18	53170718	NM_015879	51046	18q21.31	Hs.23172	7	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein amino acid glycosylation N-glycan processing glycosphingolipid biosynthetic process oligosaccharide metabolic process membrane integral to membrane integral to Golgi membrane
208670_s_at	-0.511	9.136	-2.939	1.003e-02	0.220	-2.684	EID1	EP300 interacting inhibitor of differentiation 1	15	46957581	AF274951	23741	15q21.1-q21.2	Hs.255973 Hs.714048	12	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding cellular_component nucleus cytoplasm cell cycle specific transcriptional repressor activity cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of transcription
219396_s_at	0.302	6.138	2.939	1.003e-02	0.220	-2.684	NEIL1	nei endonuclease VIII-like 1 (E. coli)	15	73426383	NM_024608	79661	15q24.2	Hs.512732	35	damaged DNA binding DNA-(apurinic or apyrimidinic site) lyase activity nucleus cytoplasm base-excision repair nucleotide-excision repair response to DNA damage stimulus response to oxidative stress protein C-terminus binding metabolic process zinc ion binding lyase activity DNA N-glycosylase activity negative regulation of nuclease activity	Base excision repair
243344_at	0.343	5.288	2.939	1.004e-02	0.220	-2.685	LOC100130054	hypothetical LOC100130054	9		BE218142	100130054	9q21.12	Hs.207074
201030_x_at	1.113	10.837	2.938	1.005e-02	0.220	-2.686	LDHB	lactate dehydrogenase B	12	-21679542	NM_002300	3945	12p12.2-p12.1	Hs.446149	27	L-lactate dehydrogenase activity binding cytoplasm oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
210296_s_at	-0.463	8.183	-2.938	1.005e-02	0.220	-2.686	PXMP3	peroxisomal membrane protein 3, 35kDa	8	-78055048	BC005375	5828	8q21.1	Hs.437966 Hs.703022	19	neuron migration protein binding peroxisome peroxisomal membrane integral to peroxisomal membrane peroxisome organization nervous system development zinc ion binding membrane integral to membrane metal ion binding
220794_at	-0.871	3.176	-2.938	1.005e-02	0.220	-2.686	GREM2	gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)	1	-238719495	NM_022469	64388	1q43	Hs.98206	9	cytokine activity extracellular region extracellular region extracellular space BMP signaling pathway
227219_x_at	0.356	7.879	2.938	1.006e-02	0.220	-2.686	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	BE857601	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
224986_s_at	-0.388	8.123	-2.938	1.006e-02	0.220	-2.686	PDPK1	3-phosphoinositide dependent protein kinase-1	16	2527970	AL040394	5170	16p13.3	Hs.459691	103	nucleotide binding 3-phosphoinositide-dependent protein kinase activity protein binding ATP binding cytoplasm cytosol plasma membrane plasma membrane negative regulation of protein kinase activity intracellular signaling cascade transferase activity peptidyl-threonine phosphorylation actin cytoskeleton organization activation of protein kinase B activity cellular response to insulin stimulus regulation of establishment of protein localization	PPAR signaling pathway mTOR signaling pathway Focal adhesion Insulin signaling pathway Endometrial cancer Prostate cancer Non-small cell lung cancer
214937_x_at	-0.462	8.865	-2.938	1.007e-02	0.220	-2.687	PCM1	pericentriolar material 1	8	17824645	AI924817	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
1554014_at	-0.581	4.405	-2.937	1.008e-02	0.220	-2.688	CHD2	chromodomain helicase DNA binding protein 2	15	91244554, 91244554	BC007347	1106	15q26	Hs.220864	9	nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter hydrolase activity
222537_s_at	-0.641	6.562	-2.937	1.008e-02	0.220	-2.688	CDC42SE1	CDC42 small effector 1	1	-149290070	W44413	56882	1q21.3	Hs.22065	4	GTPase inhibitor activity protein binding cytoplasm cytoskeleton plasma membrane phagocytosis signal transduction regulation of cell shape
241343_at	-0.489	5.153	-2.937	1.008e-02	0.220	-2.688	RNASEH1	ribonuclease H1	2	-3570565	BF127479	246243	2p25	Hs.568006	20	magnesium ion binding RNA binding endonuclease activity ribonuclease H activity ribonuclease activity cytoplasm mitochondrion RNA catabolic process hydrolase activity	DNA replication
228813_at	-0.774	8.494	-2.937	1.009e-02	0.220	-2.689	HDAC4	histone deacetylase 4	2	-239634800	AW206037	9759	2q37.3	Hs.20516 Hs.688314	83	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter skeletal system development DNA binding histone deacetylase activity nucleus cytoplasm inflammatory response cell cycle multicellular organismal development nervous system development transcription factor binding negative regulation of cell proliferation transcription repressor activity chromatin modification hydrolase activity B cell differentiation positive regulation of protein sumoylation negative regulation of striated muscle development
232844_at	0.271	3.767	2.936	1.009e-02	0.220	-2.690	IFT140	intraflagellar transport 140 homolog (Chlamydomonas)	16	-1500429	AU159127	9742	16p13.3	Hs.389438	6
229492_at	0.332	4.126	2.936	1.010e-02	0.220	-2.690	VANGL1	vang-like 1 (van gogh, Drosophila)	1	115986096	R85437	81839	1p11-p13.1	Hs.515130	12	protein binding multicellular organismal development membrane integral to membrane	Wnt signaling pathway
201068_s_at	-0.317	10.739	-2.936	1.011e-02	0.220	-2.691	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	7	102775324	NM_002803	5701	7q22.1-q22.3	Hs.437366	56	nucleotide binding proteasome complex protein binding ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
204011_at	-0.422	6.771	-2.935	1.012e-02	0.220	-2.692	SPRY2	sprouty homolog 2 (Drosophila)	13	-79808112	NM_005842	10253	13q31.1	Hs.18676	59	protein binding cytoplasm cytosol microtubule plasma membrane plasma membrane cell-cell signaling multicellular organismal development sensory perception of sound organ morphogenesis regulation of signal transduction lung development inner ear morphogenesis negative regulation of MAP kinase activity cell fate commitment branching morphogenesis of a tube	Jak-STAT signaling pathway
225331_at	-0.438	7.791	-2.935	1.013e-02	0.220	-2.693	CCDC50	coiled-coil domain containing 50	3	192529567	BF941088	152137	3q28	Hs.478682	12	protein binding cytoplasm
212932_at	-0.389	5.754	-2.934	1.014e-02	0.220	-2.694	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	AK022494	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
227111_at	0.399	5.341	2.934	1.014e-02	0.220	-2.694	ZBTB34	zinc finger and BTB domain containing 34	9	128662764	BG179317	403341	9q33.3	Hs.177633	4	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
232432_s_at	-0.527	4.678	-2.934	1.015e-02	0.220	-2.694	SLC30A5	solute carrier family 30 (zinc transporter), member 5	5	68425573, 68425637	AK022818	64924	5q12.1	Hs.631975	10	zinc ion transmembrane transporter activity membrane fraction Golgi apparatus integral to plasma membrane cation transport cobalt ion transport zinc ion transport cellular zinc ion homeostasis zinc ion binding cation transmembrane transporter activity response to zinc ion regulation of proton transport membrane apical plasma membrane secretory granule
224327_s_at	0.533	6.076	2.933	1.016e-02	0.220	-2.695	DGAT2	diacylglycerol O-acyltransferase homolog 2 (mouse)	11	75157425	AB048286	84649	11q13.5	Hs.334305	16	2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity membrane fraction endoplasmic reticulum glycerol metabolic process acyltransferase activity lipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process	Glycerolipid metabolism Retinol metabolism Metabolic pathways
218071_s_at	-0.317	7.148	-2.933	1.016e-02	0.220	-2.695	MKRN2	makorin ring finger protein 2	3	12573593	NM_014160	23609	3p25	Hs.591666	5	molecular_function nucleic acid binding protein binding intracellular biological_process zinc ion binding metal ion binding
207289_at	0.420	5.588	2.933	1.017e-02	0.220	-2.696	MMP25	matrix metallopeptidase 25	16	3036682	NM_004142	64386	16p13.3	Hs.654979	16	metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix plasma membrane proteolysis inflammatory response metabolic process peptidase activity zinc ion binding cell surface anchored to membrane
204009_s_at	-0.554	7.833	-2.933	1.017e-02	0.220	-2.696	KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	12	-25249446	W80678	3845	12p12.1	Hs.505033	430	nucleotide binding protein binding GTP binding intracellular membrane fraction plasma membrane plasma membrane endocytosis Ras protein signal transduction cell aging positive regulation of cell proliferation visual learning actin cytoskeleton organization regulation of synaptic transmission, GABAergic positive regulation of Rac protein signal transduction negative regulation of neuron apoptosis regulation of long-term neuronal synaptic plasticity striated muscle cell differentiation	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Axon guidance VEGF signaling pathway Tight junction Gap junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
222494_at	-0.324	9.126	-2.932	1.018e-02	0.220	-2.697	FOXN3	forkhead box N3	14	-88692268, -88692268	AW051527	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
218107_at	-0.488	7.763	-2.932	1.018e-02	0.220	-2.697	WDR26	WD repeat domain 26	1	-222639467	NM_025160	80232	1q42.11-q42.12	Hs.497873	8	cytoplasm
224461_s_at	-0.475	5.674	-2.932	1.018e-02	0.220	-2.697	AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2	10	-71542035	BC006121	84883	10q22.1	Hs.655377	13	DNA binding electron-transferring-flavoprotein dehydrogenase activity electron-transferring-flavoprotein dehydrogenase activity cytoplasm mitochondrion mitochondrial outer membrane cytosol induction of apoptosis apoptotic mitochondrial changes membrane integral to membrane oxidoreductase activity chromosome condensation FAD binding oxidation reduction
216083_s_at	0.365	5.442	2.932	1.018e-02	0.220	-2.698	NEU3	sialidase 3 (membrane sialidase)	11	74377597	AK022450	10825	11q13.5	Hs.191074	25	exo-alpha-sialidase activity plasma membrane integral to plasma membrane carbohydrate metabolic process ganglioside catabolic process metabolic process hydrolase activity, acting on glycosyl bonds	Other glycan degradation Sphingolipid metabolism
1555020_a_at	0.257	5.558	2.932	1.019e-02	0.220	-2.698	ARHGAP20	Rho GTPase activating protein 20	11	-109952975	BC039340	57569	11q23.1	Hs.6136	7	GTPase activator activity intracellular signal transduction
1560011_at	0.325	3.867	2.932	1.019e-02	0.220	-2.698	PSCA	prostate stem cell antigen	8	143758876	AK092432	8000	8q24.2	Hs.652235 Hs.711174	31	plasma membrane anchored to membrane
1553530_a_at	-0.850	7.157	-2.931	1.020e-02	0.220	-2.699	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	NM_033669	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1569156_at	0.399	3.068	2.931	1.021e-02	0.220	-2.700	ZNF846	zinc finger protein 846	19	-9729150	BC037359	162993	19p13.2	Hs.665717	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
34408_at	-0.558	10.274	-2.930	1.022e-02	0.220	-2.701	RTN2	reticulon 2	19	-50680389, -50680389, -50680389	AF004222	6253	19q13.32	Hs.47517	10	signal transducer activity endoplasmic reticulum signal transduction membrane integral to membrane integral to endoplasmic reticulum membrane
1569852_at	-1.099	7.982	-2.930	1.022e-02	0.220	-2.701	C7orf53	chromosome 7 open reading frame 53	7	111908143, 111908301	BC031976	286006	7q31.1	Hs.396189	5	membrane integral to membrane
207169_x_at	-0.823	6.635	-2.930	1.022e-02	0.220	-2.701	DDR1	discoidin domain receptor tyrosine kinase 1	6	30959839, 30960305, 30964443, 2300465, 2300931, 2305069, 2098794, 2099260, 2103398	NM_001954	780	6p21.3	Hs.631988	60	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding extracellular region integral to plasma membrane protein amino acid phosphorylation cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity
219213_at	0.495	6.066	2.930	1.022e-02	0.220	-2.701	JAM2	junctional adhesion molecule 2	21	25933459	NM_021219	58494	21q21.2	Hs.517227	21	plasma membrane plasma membrane integral to plasma membrane tight junction cell-cell adhesion cell junction	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
217356_s_at	-0.885	10.442	-2.930	1.022e-02	0.220	-2.701	PGK1	phosphoglycerate kinase 1	X	77246321	S81916	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
239996_x_at	0.376	6.126	2.929	1.024e-02	0.220	-2.703	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	12	109203414, 109203414	AI671237	488	12q23-q24.1	Hs.506759	84	nucleotide binding magnesium ion binding regulation of the force of heart contraction calcium-transporting ATPase activity calcium ion binding ATP binding membrane fraction microsome integral to plasma membrane ATP biosynthetic process cation transport cellular calcium ion homeostasis ER-nuclear signaling pathway cell adhesion metabolic process epidermis development membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances sarcoplasmic reticulum membrane negative regulation of heart contraction S100 alpha binding sarcoplasmic reticulum calcium ion transport	Calcium signaling pathway Cardiac muscle contraction Alzheimer's disease Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
219035_s_at	-0.553	8.558	-2.929	1.025e-02	0.220	-2.704	RNF34	ring finger protein 34	12	120322284	NM_025126	80196	12q24.31	Hs.292804	11	protein binding nucleus apoptosis zinc ion binding membrane nuclear speck ligase activity modification-dependent protein catabolic process metal ion binding
223384_s_at	-0.436	5.754	-2.928	1.027e-02	0.221	-2.705	TRIM4	tripartite motif-containing 4	7	-99325971	BE501464	89122	7q22-q31.1	Hs.50749	8	protein binding intracellular cytoplasm zinc ion binding metal ion binding protein trimerization
241984_at	0.291	4.793	2.928	1.027e-02	0.221	-2.705	FOXN3	forkhead box N3	14	-88692268, -88692268	BF984444	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
208734_x_at	-0.648	8.298	-2.927	1.028e-02	0.221	-2.706	RAB2A	RAB2A, member RAS oncogene family	8	61592112	M28213	5862	8q12.1	Hs.369017	19	nucleotide binding GTPase activity GTP binding endoplasmic reticulum Golgi apparatus ER to Golgi vesicle-mediated transport small GTPase mediated signal transduction protein transport membrane vesicle-mediated transport melanosome
217832_at	-0.514	6.738	-2.927	1.029e-02	0.221	-2.707	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	BE672181	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
222589_at	-0.456	6.459	-2.926	1.031e-02	0.221	-2.708	NLK	nemo-like kinase	17	23393814	AI967933	51701	17q11.2	Hs.208759	24	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase activity ATP binding nucleus nucleolus cytoplasm transforming growth factor beta receptor signaling pathway protein kinase cascade transcription factor binding transferase activity peptidyl-threonine phosphorylation negative regulation of Wnt receptor signaling pathway ubiquitin protein ligase binding serine phosphorylation of STAT3 protein SH2 domain binding regulation of transcription protein amino acid autophosphorylation	MAPK signaling pathway Wnt signaling pathway Adherens junction
229793_at	-0.562	5.317	-2.926	1.031e-02	0.221	-2.708	ASAH2B	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B	10	52169713	AI656964	653308	10q11.23	Hs.710005	2
205246_at	-0.512	5.991	-2.926	1.031e-02	0.221	-2.709	PEX13	peroxisomal biogenesis factor 13	2	61098315	NM_002618	5194	2p14-p16	Hs.161377	21	fatty acid alpha-oxidation neuron migration suckling behavior protein binding membrane fraction peroxisome peroxisomal membrane integral to peroxisomal membrane locomotory behavior protein transport membrane integral to membrane protein import into peroxisome matrix, docking protein import into peroxisome matrix, docking cerebral cortex cell migration microtubule-based peroxisome localization
204775_at	-0.419	5.821	-2.925	1.032e-02	0.221	-2.710	CHAF1B	chromatin assembly factor 1, subunit B (p60)	21	36679558	NM_005441	8208	21q22.13	Hs.75238	26	chromatin binding nucleus nucleoplasm chromatin assembly complex cytoplasm mitochondrion cytosol DNA replication DNA repair DNA replication-dependent nucleosome assembly protein complex assembly response to DNA damage stimulus cell cycle histone binding regulation of transcription unfolded protein binding
220984_s_at	-0.336	5.658	-2.925	1.032e-02	0.221	-2.710	SLCO5A1	solute carrier organic anion transporter family, member 5A1	8	-70747123, -70747123, -70747123	NM_030958	81796	8q13.3	Hs.152460 Hs.443609	3	transporter activity transport membrane integral to membrane
201097_s_at	-0.333	8.868	-2.925	1.032e-02	0.221	-2.710	ARF4	ADP-ribosylation factor 4	3	-57532129	NM_001660	378	3p21.2-p21.1	Hs.695943	19	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
213213_at	0.366	5.781	2.925	1.032e-02	0.221	-2.710	DIDO1	death inducer-obliterator 1	20	-61006799, -61006799, -60989013, -60979534	AL035669	11083	20q13.33	Hs.517172	18	protein binding nucleus cytoplasm transcription apoptosis zinc ion binding metal ion binding
210305_at	-1.132	11.233	-2.925	1.032e-02	0.221	-2.710	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	AB042557	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
1553367_a_at	0.372	4.957	2.925	1.033e-02	0.221	-2.710	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)	19	-60552881	NM_144613	125965	19q13.42	Hs.550544	5	cytochrome-c oxidase activity mitochondrion mitochondrial intermembrane space mitochondrial crista	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
223611_s_at	0.760	5.929	2.924	1.034e-02	0.221	-2.711	LNX1	ligand of numb-protein X 1	4	-54021193, -54021193	AI738919	84708	4q12	Hs.518760 Hs.624833	22	ubiquitin-protein ligase activity protein binding cytoplasm zinc ion binding ligase activity PDZ domain binding protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding protein homooligomerization
214764_at	-0.793	6.634	-2.924	1.035e-02	0.221	-2.712	RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	1	216525251	AW029169	51018	1q41	Hs.660109	8	protein binding
205321_at	-0.901	5.896	-2.924	1.035e-02	0.221	-2.712	EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	X	23982985	NM_001415	1968	Xp22.2-p22.1	Hs.539684	21	nucleotide binding translation initiation factor activity GTPase activity protein binding GTP binding cytosol translational initiation
236600_at	-0.471	5.738	-2.924	1.035e-02	0.221	-2.713	SPG20	spastic paraplegia 20 (Troyer syndrome)	13	-35773776, -35773776, -35773776	AI651603	23111	13q13.3	Hs.440414	19	cell death
219126_at	-0.637	7.551	-2.924	1.036e-02	0.221	-2.713	PHF10	PHD finger protein 10	6	-169845925	NM_018288	55274	6q27	Hs.435933	14	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
218386_x_at	-0.485	7.794	-2.924	1.036e-02	0.221	-2.713	USP16	ubiquitin specific peptidase 16	21	29318808	NM_006447	10600	21q22.11	Hs.99819	15	transcription coactivator activity cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity nucleus cytoplasm ubiquitin-dependent protein catabolic process cell cycle mitosis peptidase activity zinc ion binding chromatin modification histone deubiquitination histone binding ubiquitin binding regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization cell division
1555778_a_at	-1.235	3.054	-2.924	1.036e-02	0.221	-2.713	POSTN	periostin, osteoblast specific factor	13	-37034719	AY140646	10631	13q13.3	Hs.136348	38	skeletal system development protein binding extracellular region proteinaceous extracellular matrix cell adhesion heparin binding
228480_at	-0.640	6.708	-2.923	1.036e-02	0.221	-2.713	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	18	9903954	AW296039	9218	18p11.22	Hs.699980	18	signal transducer activity structural molecule activity protein binding membrane fraction endoplasmic reticulum microtubule plasma membrane tight junction membrane fusion integral to membrane vesicle positive regulation of I-kappaB kinase/NF-kappaB cascade protein heterodimerization activity perinuclear region of cytoplasm	Tight junction
1553874_a_at	0.333	4.069	2.923	1.037e-02	0.221	-2.714	ZSCAN10	zinc finger and SCAN domain containing 10	16	-3078895	NM_032805	84891	16p13.3	Hs.334515	4	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1556960_a_at	0.367	4.074	2.923	1.037e-02	0.221	-2.714	hCG_2007354	hCG2007354	12		AK057223	647589	12q24.33	Hs.703008	2
235408_x_at	0.698	3.536	2.923	1.037e-02	0.221	-2.714	ZNF117	zinc finger protein 117	7	-64072264	AW058673	51351	7q11.21	Hs.250693	5	molecular_function transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding metal ion binding
213131_at	-0.877	6.098	-2.921	1.041e-02	0.221	-2.717	OLFM1	olfactomedin 1	9	137106909, 137106923	R38389	10439	9q34.3	Hs.522484	9	protein binding endoplasmic reticulum endoplasmic reticulum lumen multicellular organismal development nervous system development membrane
201014_s_at	-0.598	6.343	-2.920	1.043e-02	0.221	-2.719	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	4	56996671, 56997025	NM_006452	10606	4q12	Hs.518774 Hs.709570	16	nucleotide binding phosphoribosylaminoimidazole carboxylase activity phosphoribosylaminoimidazolesuccinocarboxamide synthase activity ATP binding purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process purine base biosynthetic process lyase activity ligase activity identical protein binding	Purine metabolism Metabolic pathways
209841_s_at	-1.247	4.453	-2.920	1.044e-02	0.221	-2.720	LRRN3	leucine rich repeat neuronal 3	7	110518297	AL442092	54674	7q31.1	Hs.3781	6	protein binding membrane integral to membrane
232054_at	-1.412	3.202	-2.920	1.044e-02	0.221	-2.720	PCDH20	protocadherin 20	13	-60881819	AA040057	64881	13q21	Hs.391781	9	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
212764_at	-0.403	9.713	-2.920	1.044e-02	0.221	-2.720	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	AI806174	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
217227_x_at	0.314	5.527	2.920	1.045e-02	0.221	-2.721	IGL@	immunoglobulin lambda locus	22		X93006	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
222907_x_at	-0.878	5.851	-2.919	1.045e-02	0.221	-2.721	TMEM50B	transmembrane protein 50B	21	-33743317	BC000569	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
223428_s_at	-0.347	6.391	-2.919	1.046e-02	0.221	-2.722	ISY1	ISY1 splicing factor homolog (S. cerevisiae)	3	-130330924	AI761808	57461	3q21.3	Hs.512661	7	nucleus spliceosomal complex nucleolus cytoplasm mRNA processing RNA splicing
224752_at	-0.278	9.383	-2.918	1.048e-02	0.221	-2.723	PL-5283	PL-5283 protein	7	134997760	BG031051	647087	7q33	Hs.200022	3
205289_at	-0.328	4.035	-2.917	1.049e-02	0.221	-2.724	BMP2	bone morphogenetic protein 2	20	6696744	AA583044	650	20p12	Hs.73853	195	branching involved in ureteric bud morphogenesis cytokine activity extracellular region extracellular region extracellular space inflammatory response cell-cell signaling growth factor activity negative regulation of cell proliferation embryonic development organ morphogenesis positive regulation of pathway-restricted SMAD protein phosphorylation specific transcriptional repressor activity positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway negative regulation of gene-specific transcription cardiac cell differentiation growth odontogenesis of dentine-containing tooth cell fate commitment positive regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter SMAD binding positive regulation of astrocyte differentiation cartilage development cardiac epithelial to mesenchymal transition	Cytokine-cytokine receptor interaction Hedgehog signaling pathway TGF-beta signaling pathway Pathways in cancer Basal cell carcinoma
222790_s_at	0.504	5.770	2.917	1.049e-02	0.221	-2.725	RSBN1	round spermatid basic protein 1	1	-114105976	AK022166	54665	1p13.2	Hs.486285	6	protein binding nucleus
240381_at	0.368	5.864	2.917	1.050e-02	0.221	-2.725	ZBED5	zinc finger, BED-type containing 5	11	-10830829	AA813103	58486	11p15.3	Hs.655066	5	DNA binding zinc ion binding metal ion binding
232265_at	0.405	4.381	2.917	1.050e-02	0.221	-2.725	ATXN7L1	ataxin 7-like 1	7	-105187871, -105032456, -105032456	BC003517	222255	7q22.3	Hs.489603	8
201314_at	-0.491	8.009	-2.917	1.050e-02	0.221	-2.725	STK25	serine/threonine kinase 25 (STE20 homolog, yeast)	2	-242083104	NM_006374	10494	2q37.3	Hs.516807	12	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus protein amino acid phosphorylation response to oxidative stress signal transduction transferase activity identical protein binding
200626_s_at	-0.550	8.092	-2.916	1.052e-02	0.222	-2.727	MATR3	matrin 3	5	138637690, 138657253	NM_018834	9782	5q31.2	Hs.268939	24	nucleotide binding RNA binding structural molecule activity protein binding intracellular nucleus nuclear inner membrane zinc ion binding nuclear matrix metal ion binding
217503_at	-0.373	2.709	-2.916	1.052e-02	0.222	-2.727	STK17B	serine/threonine kinase 17b	2	-196706552	AA203487	9262	2q32.3	Hs.710234 Hs.88297	7	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade actin cytoskeleton transferase activity
238805_at	-0.596	5.372	-2.916	1.052e-02	0.222	-2.727	C11orf52	chromosome 11 open reading frame 52	11	111294810	AA991551	91894	11q23.1	Hs.97013	3
218848_at	-0.365	6.025	-2.916	1.053e-02	0.222	-2.727	THOC6	THO complex 6 homolog (Drosophila)	16	3014032	NM_024339	79228	16p13.3	Hs.412304	2
205329_s_at	-0.459	5.602	-2.915	1.054e-02	0.222	-2.728	SNX4	sorting nexin 4	3	-126648183	NM_003794	8723	3q21.2	Hs.507243	9	protein binding cytoplasm endocytosis cell communication protein transport phosphoinositide binding
205788_s_at	-0.434	9.858	-2.915	1.055e-02	0.222	-2.730	ZC3H11A	zinc finger CCCH-type containing 11A	1	202031373	NM_014827	9877	1q32.1	Hs.532399	13	nucleic acid binding protein binding zinc ion binding metal ion binding
213152_s_at	-0.544	5.915	-2.915	1.055e-02	0.222	-2.730	SFRS2B	splicing factor, arginine/serine-rich 2B	11	94439703	AI343248	10929	11q22	Hs.476680 Hs.713908	6	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
214182_at	-0.637	6.108	-2.914	1.056e-02	0.222	-2.730	ARF6	ADP-ribosylation factor 6	14	49429485	AA243143	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
221688_s_at	-0.481	8.008	-2.914	1.056e-02	0.222	-2.731	IMP3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)	15	-73718490	AL136913	55272	15q24	Hs.513043	21	protein binding intracellular nucleus nucleolus rRNA processing rRNA binding ribonucleoprotein complex
205638_at	0.430	2.509	2.914	1.057e-02	0.222	-2.731	BAI3	brain-specific angiogenesis inhibitor 3	6	69402352	NM_001704	577	6q12	Hs.13261	8	plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane brain-specific angiogenesis inhibitor activity
243313_at	-0.564	10.623	-2.914	1.057e-02	0.222	-2.731	SYNPO2L	synaptopodin 2-like	10	-75074649, -75074649	AI141151	79933	10q22.2	Hs.645273	4	actin binding protein binding cytoplasm cytoskeleton
224378_x_at	0.381	7.995	2.914	1.057e-02	0.222	-2.731	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	AF276658	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
202115_s_at	-0.239	6.997	-2.914	1.057e-02	0.222	-2.731	NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	1	-869445	NM_015658	26155	1p36.33	Hs.405987	23	protein binding nucleus nucleolus
212998_x_at	0.931	5.689	2.914	1.057e-02	0.222	-2.732	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	AI583173	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
219625_s_at	-0.530	6.892	-2.912	1.060e-02	0.222	-2.734	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	5	-74702683, -74702683	NM_005713	10087	5q13.3	Hs.270437	26	protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response
214910_s_at	0.338	5.372	2.912	1.061e-02	0.222	-2.734	APOM	apolipoprotein M	6	31731649, 3069795, 2871254	AF161454	55937	6p21.33	Hs.534468	38	lipid transporter activity protein binding extracellular region cytosol integral to plasma membrane lipid transport defense response response to unfolded protein response to nutrient cholesterol efflux cholesterol efflux very-low-density lipoprotein particle low-density lipoprotein particle discoidal high-density lipoprotein particle spherical high-density lipoprotein particle high-density lipoprotein particle remodeling high-density lipoprotein particle assembly high-density lipoprotein particle clearance lipoprotein metabolic process cholesterol homeostasis protein complex reverse cholesterol transport NF-kappaB binding negative regulation of lipoprotein lipid oxidation
211081_s_at	-0.472	3.392	-2.911	1.062e-02	0.222	-2.736	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	14	-49954992	Z25426	11183	14q11.2-q21	Hs.130491	14	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding cytoplasm protein amino acid phosphorylation response to stress protein kinase cascade activation of JUN kinase activity transferase activity
1552722_at	-0.506	3.196	-2.911	1.062e-02	0.222	-2.736	ARPP-21	cyclic AMP-regulated phosphoprotein, 21 kD	3	35658852, 35696119, 35697432	NM_016300	10777	3p22.3	Hs.475902 Hs.713605	7	molecular_function nucleic acid binding cellular_component cytoplasm biological_process
202089_s_at	-0.689	5.649	-2.911	1.063e-02	0.222	-2.736	SLC39A6	solute carrier family 39 (zinc transporter), member 6	18	-31944960, -31942491	NM_012319	25800	18q12.2	Hs.719277	13	endoplasmic reticulum plasma membrane ion transport zinc ion transport zinc ion binding integral to membrane metal ion transport metal ion transmembrane transporter activity
226723_at	-0.531	6.985	-2.911	1.063e-02	0.222	-2.737	CCDC23	coiled-coil domain containing 23	1	-43045309	AI581511	374969	1p34.2	Hs.113919	4
228746_s_at	-0.656	8.292	-2.910	1.066e-02	0.223	-2.739	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	AV646549	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
1559190_s_at	0.552	5.767	2.910	1.066e-02	0.223	-2.739	RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	19	-60247503, -60247503	AL833150	112724	19q13.42	Hs.327631	9	binding oxidoreductase activity oxidation reduction
226012_at	-0.489	6.994	-2.909	1.067e-02	0.223	-2.740	ANKRD11	ankyrin repeat domain 11	16	-87861535	AI686514	29123	16q24.3	Hs.335003	8	nucleus
228977_at	-1.121	7.946	-2.909	1.067e-02	0.223	-2.740	LOC729680	hypothetical protein LOC729680	13		AI669535	729680	13q12.11	Hs.130652	1
218521_s_at	-0.850	6.304	-2.909	1.067e-02	0.223	-2.740	UBE2W	ubiquitin-conjugating enzyme E2W (putative)	8	-74865393	NM_018299	55284	8q21.11	Hs.597486	7	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
207711_at	0.351	4.588	2.909	1.067e-02	0.223	-2.740	C20orf117	chromosome 20 open reading frame 117	20	-34839258	NM_015377	140710	20q11.23	Hs.460807 Hs.719179	8
234486_at	0.445	5.275	2.908	1.069e-02	0.223	-2.741	OR51B2	olfactory receptor, family 51, subfamily B, member 2	11	-5301103	AF137396	79345	11p15	Hs.680163	4	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
212150_at	-0.615	8.492	-2.908	1.069e-02	0.223	-2.742	EFR3A	EFR3 homolog A (S. cerevisiae)	8	132985540	AA805651	23167	8q24.22	Hs.204564	4	binding plasma membrane
209061_at	-0.595	7.687	-2.908	1.070e-02	0.223	-2.742	NCOA3	nuclear receptor coactivator 3	20	45564063	AI761748	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
222448_s_at	-0.569	7.474	-2.908	1.070e-02	0.223	-2.742	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	1	47572055	AF112216	51727	1p32	Hs.714325	16	nucleotide binding cytidylate kinase activity uridine kinase activity ATP binding nucleus cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine ribonucleotide biosynthetic process transferase activity phosphotransferase activity, phosphate group as acceptor	Pyrimidine metabolism Metabolic pathways
238647_at	-0.607	5.084	-2.908	1.070e-02	0.223	-2.742	C14orf28	chromosome 14 open reading frame 28	14	44436256	AA496213	122525	14q21.2	Hs.82098	3
229439_s_at	0.386	5.334	2.907	1.071e-02	0.223	-2.743	RBM47	RNA binding motif protein 47	4	-40120028, -40120028	AI830823	54502	4p13-p12	Hs.518727	4	RNA binding nucleus
206867_at	0.317	5.045	2.907	1.072e-02	0.223	-2.744	GCKR	glucokinase (hexokinase 4) regulator	2	27573209	NM_001486	2646	2p23	Hs.89771	41	protein import into nucleus, translocation cellular glucose homeostasis enzyme inhibitor activity protein binding nucleus nucleoplasm cytosol
216512_s_at	0.315	4.479	2.907	1.072e-02	0.223	-2.744	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	AL139318	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
210378_s_at	-0.270	7.301	-2.907	1.072e-02	0.223	-2.744	SSNA1	Sjogren syndrome nuclear autoantigen 1	9	139202874	BC004118	8636	9q34.3	Hs.530314	6	nucleus centrosome identical protein binding
230721_at	0.382	5.654	2.905	1.076e-02	0.223	-2.747	C16orf52	chromosome 16 open reading frame 52	16	21927030	BF436957	730094	16p12.2	Hs.498890	3
212461_at	-0.394	8.606	-2.904	1.078e-02	0.223	-2.749	AZIN1	antizyme inhibitor 1	8	-103907711	BF793951	51582	8q22.3	Hs.459106	10	catalytic activity protein binding polyamine biosynthetic process ornithine decarboxylase inhibitor activity ornithine decarboxylase activator activity
227456_s_at	0.386	8.877	2.904	1.078e-02	0.223	-2.749	C6orf136	chromosome 6 open reading frame 136	6	30722794, 2063373, 1861669	BF224092	221545	6p21.33	Hs.591787	7
226533_at	-0.610	6.519	-2.903	1.080e-02	0.224	-2.751	HINT3	histidine triad nucleotide binding protein 3	6	126319553	BF694956	135114	6q22.32	Hs.72325	6	nucleus cytoplasm hydrolase activity
238648_at	0.335	4.713	2.903	1.081e-02	0.224	-2.751	FLJ42291	hypothetical LOC346547	7		BE671597	346547	7q36.2
218403_at	-0.373	9.088	-2.903	1.081e-02	0.224	-2.752	TRIAP1	TP53 regulated inhibitor of apoptosis 1	12	-119366146	NM_016399	51499	12q24.31	Hs.69499	7	protein binding cytoplasm mitochondrion apoptosis anti-apoptosis DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest caspase inhibitor activity perinuclear region of cytoplasm
221577_x_at	1.988	4.455	2.903	1.081e-02	0.224	-2.752	GDF15	growth differentiation factor 15	19	18357967	AF003934	9518	19p13.11	Hs.616962	77	cytokine activity extracellular region extracellular space signal transduction transforming growth factor beta receptor signaling pathway cell-cell signaling growth factor activity
220241_at	-0.524	3.100	-2.902	1.082e-02	0.224	-2.752	TMCO3	transmembrane and coiled-coil domains 3	13	113193308	NM_017905	55002	13q34	Hs.317593	6	cation transport antiporter activity solute:hydrogen antiporter activity membrane integral to membrane
215546_at	0.432	4.404	2.902	1.083e-02	0.224	-2.753	PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	9	-122618152	AK001065	5711	9q33.2	Hs.193725	39	proteasome complex binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
204026_s_at	-0.408	4.881	-2.902	1.083e-02	0.224	-2.753	ZWINT	ZW10 interactor	10	-57787204	NM_007057	11130	10q21-q22	Hs.591363	17	mitotic sister chromatid segregation condensed chromosome kinetochore nucleus cell cycle spindle organization mitotic cell cycle checkpoint protein N-terminus binding phosphoinositide-mediated signaling cell division establishment of localization in cell
204022_at	-0.407	6.298	-2.901	1.084e-02	0.224	-2.754	WWP2	WW domain containing E3 ubiquitin protein ligase 2	16	68353774, 68353774, 68516401	AI668780	11060	16q22.1	Hs.408458	20	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding intracellular protein modification process negative regulation of gene expression protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process negative regulation of transporter activity interspecies interaction between organisms entry of virus into host cell negative regulation of protein transport	Ubiquitin mediated proteolysis
210347_s_at	0.354	3.668	2.900	1.086e-02	0.224	-2.756	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	2	-60537832, -60531805	AF080216	53335	2p16.1	Hs.370549	26	nucleic acid binding intracellular nucleus cytoplasm zinc ion binding hemopoiesis regulation of transcription metal ion binding
217992_s_at	0.326	5.492	2.900	1.086e-02	0.224	-2.756	EFHD2	EF-hand domain family, member D2	1	15608977	NM_024329	79180	1p36.21	Hs.465374	8	calcium ion binding protein binding
233438_at	0.460	4.141	2.899	1.090e-02	0.224	-2.759	C6orf162	chromosome 6 open reading frame 162	6	88089024	AK024130	57150	6q15-q16.1	Hs.70769	4	membrane integral to membrane
213744_at	-0.476	4.784	-2.899	1.090e-02	0.224	-2.759	ATRNL1	attractin-like 1	10	116843113	AI817331	26033	10q26	Hs.501127	3	binding sugar binding membrane integral to membrane
46323_at	0.376	6.002	2.899	1.090e-02	0.224	-2.759	CANT1	calcium activated nucleotidase 1	17	-74499392	AL120741	124583	17q25.3	Hs.8859	13	signal transducer activity calcium ion binding endoplasmic reticulum Golgi apparatus membrane integral to membrane hydrolase activity nucleoside-diphosphatase activity positive regulation of I-kappaB kinase/NF-kappaB cascade	Purine metabolism Pyrimidine metabolism
215368_at	-0.644	8.289	-2.898	1.091e-02	0.224	-2.760	NEB	nebulin	2	-152050098	R78299	4703	2q22	Hs.588655	32	actin binding protein binding cytoplasm somatic muscle development structural constituent of muscle actin cytoskeleton sarcomere Z disc regulation of actin filament length
235106_at	0.451	3.272	2.898	1.091e-02	0.224	-2.760	MAML2	mastermind-like 2 (Drosophila)	11	-95351087	AW847318	84441	11q21	Hs.428214	17	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
237793_at	0.413	4.363	2.898	1.092e-02	0.225	-2.761	LOC100128496	similar to chromosome 20 open reading frame 78	20		AW118618	100128496	20p11.23	Hs.664484
205037_at	0.380	6.350	2.897	1.095e-02	0.225	-2.763	RABL4	RAB, member of RAS oncogene family-like 4	22	-35484200	NM_006860	11020	22q13.1	Hs.415172	6	nucleotide binding GTP binding small GTPase mediated signal transduction
208633_s_at	-0.517	6.467	-2.896	1.095e-02	0.225	-2.763	MACF1	microtubule-actin crosslinking factor 1	1	39319704, 39569396	W61052	23499	1p32-p31	Hs.580782	25	calcium ion binding calcium ion binding protein binding cytoplasm cytoplasm cytoskeleton cytoskeleton cell cycle arrest microtubule binding biological_process actin filament binding
218191_s_at	-0.626	8.686	-2.896	1.097e-02	0.225	-2.765	LMBRD1	LMBR1 domain containing 1	6	-70442469	NM_018368	55788	6q13	Hs.271643	9	lysosome transport membrane integral to membrane cobalamin binding interspecies interaction between organisms cobalt ion binding
230040_at	0.769	3.671	2.895	1.099e-02	0.226	-2.766	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	16	-75873525	AI733120	170692	16q23	Hs.188746	9	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
206538_at	-0.512	6.518	-2.895	1.099e-02	0.226	-2.766	MRAS	muscle RAS oncogene homolog	3	139549314, 139550197	NM_012219	22808	3q22.3	Hs.527021	18	nucleotide binding GTPase activity GTP binding intracellular plasma membrane Ras protein signal transduction multicellular organismal development muscle organ development actin cytoskeleton organization GTP-dependent protein binding	MAPK signaling pathway Tight junction Regulation of actin cytoskeleton
203935_at	-0.640	7.479	-2.893	1.102e-02	0.226	-2.769	ACVR1	activin A receptor, type I	2	-158301204, -158301204	NM_001105	90	2q23-q24	Hs.470316	53	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding patterning of blood vessels urogenital system development in utero embryonic development gastrulation with mouth forming second mesoderm formation neural crest cell migration acute inflammatory response receptor activity ATP binding protein amino acid phosphorylation transforming growth factor beta receptor signaling pathway germ cell development determination of left/right symmetry mesoderm development heart development embryonic development membrane activin receptor activity, type I transferase activity manganese ion binding regulation of ossification positive regulation of bone mineralization BMP signaling pathway negative regulation of activin receptor signaling pathway protein homodimerization activity negative regulation of apoptosis apical part of cell positive regulation of osteoblast differentiation positive regulation of transcription SMAD binding activin receptor complex follistatin binding activin binding regulation of skeletal muscle tissue development transforming growth factor beta binding smooth muscle cell differentiation pharyngeal system development	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
231114_at	0.673	2.627	2.893	1.102e-02	0.226	-2.769	SPATA22	spermatogenesis associated 22	17	-3290063	BF438413	84690	17p13.3	Hs.351068	3
1567410_at	0.295	6.402	2.893	1.103e-02	0.226	-2.770	ZNF135	zinc finger protein 135	19	63262423	X65231	7694	19q13.4	Hs.85863	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
220201_at	-0.379	5.261	-2.892	1.105e-02	0.226	-2.772	RC3H2	ring finger and CCCH-type zinc finger domains 2	9	-124655844, -124651552	NM_018835	54542	9q34	Hs.533499	6	DNA binding protein binding membrane fraction cytoplasm biological_process zinc ion binding cell surface membrane metal ion binding perinuclear region of cytoplasm
218160_at	0.473	10.633	2.892	1.105e-02	0.226	-2.772	NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	9	-123946158	NM_014222	4702	9q33.2-q34.11	Hs.495039	12	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
228785_at	-0.464	7.557	-2.892	1.106e-02	0.226	-2.772	ZNF281	zinc finger protein 281	1	-198642042	AA121673	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
224674_at	0.316	6.640	2.891	1.106e-02	0.226	-2.772	TTYH3	tweety homolog 3 (Drosophila)	7	2638128	AI934753	80727	7p22	Hs.440899	5	ion channel activity chloride channel activity calcium ion binding plasma membrane ion transport integral to membrane chloride ion binding chloride channel complex
202822_at	0.536	7.884	2.891	1.107e-02	0.226	-2.773	LPP	LIM domain containing preferred translocation partner in lipoma	3	189413414	BF221852	4026	3q28	Hs.444362	30	molecular_function protein binding cellular_component nucleus cytoplasm plasma membrane focal adhesion cell adhesion biological_process zinc ion binding cell junction metal ion binding
200977_s_at	-0.530	9.292	-2.890	1.109e-02	0.227	-2.774	TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	7	27746262	AF090891	8887	7p15	Hs.34576	21	intracellular apoptosis anti-apoptosis zinc ion binding identical protein binding
212785_s_at	-0.425	7.489	-2.890	1.109e-02	0.227	-2.775	LARP7	La ribonucleoprotein domain family, member 7	4	113777568, 113778060	AA160181	51574	4q25	Hs.713663	11	nucleotide binding RNA binding nucleus nucleoplasm cytoplasm Golgi apparatus RNA processing ribonucleoprotein complex
229650_s_at	-0.301	6.526	-2.890	1.110e-02	0.227	-2.775	C19orf42	chromosome 19 open reading frame 42	19	-16617958	BG538931	79086	19p13.11	Hs.356467	1	membrane integral to membrane
1564463_at	0.444	5.465	2.890	1.110e-02	0.227	-2.776	LOC283711	hypothetical protein LOC283711	15		AK093758	283711	15q13.3	Hs.585100	1
201504_s_at	-0.465	6.247	-2.890	1.110e-02	0.227	-2.776	TSN	translin	2	122229590	AI435302	7247	2q21.1	Hs.75066	28	nucleus cytoplasm DNA recombination sequence-specific DNA binding
206492_at	0.705	5.547	2.889	1.113e-02	0.227	-2.778	FHIT	fragile histidine triad gene	3	-59710075	NM_002012	2272	3p14.2	Hs.715588 Hs.715597	164	magnesium ion binding protein binding cytoplasm DNA replication nucleotide metabolic process hydrolase activity manganese ion binding bis(5'-adenosyl)-triphosphatase activity	Purine metabolism Small cell lung cancer Non-small cell lung cancer
212643_at	-0.360	8.572	-2.888	1.114e-02	0.227	-2.779	MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	14	54588114	AI671747	93487	14q22.3	Hs.594338 Hs.619374	8
231582_at	0.527	3.789	2.887	1.116e-02	0.227	-2.780	FLJ23834	hypothetical protein FLJ23834	7	105390892	BE467322	222256	7q22.3	Hs.150120	4	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
216893_s_at	-1.022	4.069	-2.886	1.118e-02	0.228	-2.782	COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	2	227737524	U02519	1285	2q36-q37	Hs.570065	77	integrin binding integrin binding extracellular matrix structural constituent protein binding extracellular region collagen collagen type IV induction of apoptosis activation of caspase activity cell adhesion cell surface receptor linked signal transduction sensory perception of sound blood circulation metalloendopeptidase inhibitor activity negative regulation of cell proliferation negative regulation of angiogenesis
203460_s_at	-0.455	5.881	-2.886	1.119e-02	0.228	-2.783	PSEN1	presenilin 1	14	72672895	NM_007318	5663	14q24.3	Hs.3260	386	kinetochore endopeptidase activity membrane fraction integral to nuclear inner membrane nuclear outer membrane mitochondrion endoplasmic reticulum Golgi apparatus integral to plasma membrane membrane protein ectodomain proteolysis apoptosis anti-apoptosis chromosome segregation Notch receptor processing intracellular signaling cascade beta-catenin binding cell death peptidase activity cell surface membrane cell-cell adhesion protein processing PDZ domain binding endoplasmic reticulum calcium ion homeostasis regulation of phosphorylation amyloid precursor protein catabolic process positive regulation of catalytic activity	Wnt signaling pathway Notch signaling pathway Neurotrophin signaling pathway Alzheimer's disease
236381_s_at	-0.618	5.023	-2.885	1.121e-02	0.228	-2.784	WDR8	WD repeat domain 8	1	-3537191	AW572779	49856	1p36.3	Hs.31714	8	protein binding cytoplasm
226183_at	-0.360	6.525	-2.885	1.122e-02	0.228	-2.785	GSK3B	glycogen synthase kinase 3 beta	3	-121023493	AW139538	2932	3q13.3	Hs.445733 Hs.593022	373	nucleotide binding re-entry into mitotic cell cycle p53 binding glycogen synthase kinase 3 activity ATP binding nucleus cytoplasm cytosol cytosol glycogen metabolic process anti-apoptosis response to stress ER overload response intracellular signaling cascade beta-catenin binding organ morphogenesis transferase activity peptidyl-serine phosphorylation growth cone beta-catenin destruction complex positive regulation of protein complex assembly protein kinase A catalytic subunit binding Axin-APC-beta-catenin-GSK3B complex cell soma dendritic shaft membrane-bounded organelle fat cell differentiation positive regulation of protein export from nucleus tau-protein kinase activity NF-kappaB binding Wnt receptor signaling pathway through beta-catenin	ErbB signaling pathway Chemokine signaling pathway Cell cycle Wnt signaling pathway Hedgehog signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Insulin signaling pathway Melanogenesis Alzheimer's disease Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Basal cell carcinoma
203116_s_at	-0.300	7.941	-2.884	1.124e-02	0.228	-2.786	FECH	ferrochelatase (protoporphyria)	18	-53363070	NM_000140	2235	18q21.3	Hs.365365	61	ferrochelatase activity ferrochelatase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix generation of precursor metabolites and energy heme biosynthetic process ferrous iron binding response to light stimulus detection of UV membrane protoporphyrinogen IX metabolic process metal ion binding 2 iron, 2 sulfur cluster binding	Porphyrin and chlorophyll metabolism Metabolic pathways
232524_x_at	-0.423	6.754	-2.884	1.124e-02	0.228	-2.787	ANAPC4	anaphase promoting complex subunit 4	4	24987945	AK001881	29945	4p15.2	Hs.152173	21	G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
228463_at	0.327	3.830	2.883	1.124e-02	0.228	-2.787	FOXA3	forkhead box A3	19	51059357	R99562	3171	19q13.2-q13.4	Hs.36137	14	cellular glucose homeostasis transcription factor activity nucleus regulation of transcription, DNA-dependent cellular response to starvation sequence-specific DNA binding	Maturity onset diabetes of the young
1566149_at	0.245	5.226	2.883	1.125e-02	0.228	-2.788	CALML4	calmodulin-like 4	15	-66270096	AK096198	91860	15q23	Hs.709550	4	calcium ion binding
226071_at	0.820	4.909	2.883	1.125e-02	0.228	-2.788	ADAMTSL4	ADAMTS-like 4	1	148788521, 148788521	AF217974	54507	1q21.3	Hs.516243	16	protease binding metalloendopeptidase activity protein binding extracellular region peptidase activity extracellular matrix positive regulation of apoptosis
226284_at	-0.643	5.152	-2.883	1.126e-02	0.228	-2.789	ZBTB2	zinc finger and BTB domain containing 2	6	-151726942	BF111616	57621	6q25.1	Hs.520073	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
218129_s_at	-0.660	6.516	-2.882	1.128e-02	0.229	-2.790	NFYB	nuclear transcription factor Y, beta	12	-103034987	NM_006166	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
223145_s_at	-0.501	8.565	-2.881	1.130e-02	0.229	-2.792	AKIRIN2	akirin 2	6	-88441298	BC000764	55122	6q15	Hs.485915	10	protein binding nucleus embryonic development transcriptional repressor complex response to lipopolysaccharide positive regulation of interleukin-6 production innate immune response regulation of transcription positive regulation of transcription from RNA polymerase II promoter
37424_at	0.310	6.411	2.880	1.132e-02	0.229	-2.793	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AB029343	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
218899_s_at	0.523	3.636	2.880	1.132e-02	0.229	-2.793	BAALC	brain and acute leukemia, cytoplasmic	8	104222096	NM_024812	79870	8q22.3	Hs.533446	11	cytoplasm membrane
230150_at	-0.451	5.665	-2.880	1.132e-02	0.229	-2.793	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	N57499	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
218310_at	-0.444	7.602	-2.880	1.132e-02	0.229	-2.793	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	7	65843077	NM_014504	27342	7q11.21	Hs.530053	20	DNA binding protein binding cytoplasm early endosome endocytosis zinc ion binding protein transport modification-dependent protein catabolic process metal ion binding recycling endosome
213248_at	0.292	3.705	2.879	1.133e-02	0.229	-2.794	LOC730101	hypothetical LOC730101	6	52637157	AL577024	730101	6p12.2	Hs.7921	2
201878_at	-0.566	7.485	-2.879	1.134e-02	0.229	-2.795	ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	15	70553720	N25546	25820	15q24	Hs.268787	11	ubiquitin ligase complex protein binding cytoplasm ubiquitin-dependent protein catabolic process zinc ion binding small conjugating protein ligase activity metal ion binding
225426_at	-0.886	8.192	-2.879	1.135e-02	0.229	-2.795	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	AW195360	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
1556285_s_at	0.309	8.790	2.879	1.135e-02	0.229	-2.796	PPA2	pyrophosphatase (inorganic) 2	4	-106509682	AF086012	27068	4q25	Hs.654957	13	magnesium ion binding inorganic diphosphatase activity cytoplasm mitochondrion phosphate metabolic process hydrolase activity	Oxidative phosphorylation
231775_at	0.328	5.075	2.878	1.137e-02	0.229	-2.797	TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	8	-23104914	W65310	8797	8p21	Hs.591834	95	receptor activity death receptor activity induction of apoptosis activation of caspase activity signal transduction activation of NF-kappaB-inducing kinase activity transcription factor binding induction of apoptosis via death domain receptors caspase activator activity membrane integral to membrane TRAIL binding	Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity
204263_s_at	0.567	6.825	2.878	1.137e-02	0.229	-2.798	CPT2	carnitine palmitoyltransferase 2	1	53434688	M58581	1376	1p32	Hs.713535	53	carnitine O-palmitoyltransferase activity carnitine O-palmitoyltransferase activity mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport carnitine shuttle acyltransferase activity membrane transferase activity regulation of fatty acid oxidation	Fatty acid metabolism PPAR signaling pathway
241533_at	0.303	5.388	2.877	1.139e-02	0.229	-2.799	LOC731656	hypothetical LOC731656	1		AV652367	731656		Hs.702477	1
213508_at	-0.568	7.095	-2.877	1.139e-02	0.229	-2.799	C14orf147	chromosome 14 open reading frame 147	14	-33971894	AA142942	171546	14q13.1	Hs.269909	5	serine C-palmitoyltransferase activity protein binding endoplasmic reticulum membrane integral to membrane serine C-palmitoyltransferase complex sphingolipid biosynthetic process
1555996_s_at	-0.668	3.768	-2.877	1.140e-02	0.229	-2.800	EIF4A2	eukaryotic translation initiation factor 4A, isoform 2	3	187984054	AI332397	1974	3q28	Hs.518475 Hs.599481	15	nucleotide binding RNA binding translation initiation factor activity helicase activity protein binding ATP binding cytosol translation regulation of translational initiation ATP-dependent helicase activity eukaryotic translation initiation factor 4F complex hydrolase activity interspecies interaction between organisms
1565823_at	-0.375	3.155	-2.877	1.140e-02	0.229	-2.800	SEPT7	septin 7	7	35807151	BF855173	989	7p14.3-p14.1	Hs.191346 Hs.642540	23	nucleotide binding condensed chromosome kinetochore cytokinesis stress fiber structural molecule activity protein binding GTP binding nucleus cytoplasm spindle cell cycle mitosis septin complex protein heterooligomerization
224883_at	-0.680	6.155	-2.877	1.140e-02	0.229	-2.800	PLDN	pallidin homolog (mouse)	15	43666708	AI344311	26258	15q21.1	Hs.719102	17	cellular_component cytoplasm endosome membrane fusion blood coagulation membrane synaptic vesicle docking during exocytosis melanocyte differentiation syntaxin-13 binding positive regulation of natural killer cell activation secretion of lysosomal enzymes identical protein binding pigmentation
1556283_s_at	-0.388	4.937	-2.877	1.140e-02	0.229	-2.800	FGFR1OP2	FGFR1 oncogene partner 2	12	26982582	W74643	26127	12p11.23	Hs.591162	5	cytoplasm
205084_at	-0.656	5.876	-2.876	1.140e-02	0.229	-2.800	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	NM_018844	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
208743_s_at	-0.418	8.034	-2.876	1.141e-02	0.229	-2.800	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	20	42947757	BC001359	7529	20q13.1	Hs.643544	109	cytoplasm cytosol protein targeting Ras protein signal transduction activation of pro-apoptotic gene products enzyme binding protein domain specific binding negative regulation of protein amino acid dephosphorylation melanosome positive regulation of catalytic activity perinuclear region of cytoplasm	Cell cycle Neurotrophin signaling pathway
218526_s_at	-0.477	6.841	-2.876	1.141e-02	0.229	-2.801	RANGRF	RAN guanine nucleotide release factor	17	8132713	NM_014185	29098	17p13	Hs.408233	6	guanyl-nucleotide exchange factor activity nucleus cytoplasm protein transport
230384_at	-0.884	7.912	-2.876	1.142e-02	0.229	-2.801	ANKRD23	ankyrin repeat domain 23	2	-96867377	AI866797	200539	2q11.2	Hs.643430	8	nucleus
202745_at	-0.337	7.270	-2.876	1.142e-02	0.229	-2.802	USP8	ubiquitin specific peptidase 8	15	48503870	NM_005154	9101	15q21.2	Hs.644563	25	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding ubiquitin-dependent protein catabolic process peptidase activity cell proliferation SH3 domain binding	Endocytosis
201101_s_at	-1.121	7.205	-2.873	1.148e-02	0.230	-2.806	BCLAF1	BCL2-associated transcription factor 1	6	-136619693	BE963370	9774	6q22-q23	Hs.486542	16	DNA binding protein binding nucleus cytoplasm induction of apoptosis negative regulation of transcription transcription repressor activity
228244_at	0.255	5.084	2.873	1.148e-02	0.230	-2.806	BLOC1S3	biogenesis of lysosomal organelles complex-1, subunit 3	19	50373842	BF062383	388552	19q13.32	Hs.103902 Hs.719016	7	eye development molecular_function cytoplasm cytosol platelet activation BLOC-1 complex BLOC-1 complex melanosome organization positive regulation of natural killer cell activation secretion of lysosomal enzymes response to drug identical protein binding pigmentation during development platelet dense granule organization
226581_at	-0.437	7.558	-2.872	1.150e-02	0.230	-2.808	ZFYVE20	zinc finger, FYVE domain containing 20	3	-15086583	AA524034	64145	3p25.1	Hs.475565 Hs.706478	9	intracellular endosome plasma membrane zinc ion binding protein transport endosome transport metal ion binding	Endocytosis
223756_at	-0.390	4.820	-2.872	1.151e-02	0.230	-2.808	KIAA1310	KIAA1310	2	-96622633	AL136849	55683	2p12-p11.2	Hs.516341	10
206542_s_at	-0.621	8.391	-2.872	1.151e-02	0.230	-2.808	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	AV725365	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
227733_at	0.478	3.526	2.871	1.153e-02	0.231	-2.810	TMEM63C	transmembrane protein 63C	14	76717854	AA928939	57156	14q24.3	Hs.22452	3	membrane integral to membrane
1553559_at	0.491	4.421	2.871	1.154e-02	0.231	-2.810	TMEM171	transmembrane protein 171	5	72452143	NM_173490	134285	5q13.2	Hs.162246	5	membrane integral to membrane
1558459_s_at	-0.299	5.985	-2.870	1.154e-02	0.231	-2.811	LOC401320	hypothetical LOC401320	7		BC041636	401320	7p15.1	Hs.561708	2
212383_at	-0.358	7.523	-2.870	1.156e-02	0.231	-2.812	ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1	17	37864387	AL096733	535	17q21	Hs.463074	21	protein binding cytoplasm plasma membrane ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport integral to membrane cytoplasmic vesicle proton-transporting two-sector ATPase complex, proton-transporting domain melanosome ATPase binding	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
237603_at	0.436	3.671	2.870	1.156e-02	0.231	-2.812	C1orf100	chromosome 1 open reading frame 100	1	242582559	AI122828	200159	1q44	Hs.442703	3
223583_at	0.387	5.061	2.869	1.157e-02	0.231	-2.813	TNFAIP8L2	tumor necrosis factor, alpha-induced protein 8-like 2	1	149395728	AF271774	79626	1q21.3	Hs.709522	2	protein binding innate immune response
211900_x_at	0.476	4.522	2.869	1.157e-02	0.231	-2.813	CD6	CD6 molecule	11	60495690	U66146	923	11q13	Hs.643167	22	scavenger receptor activity protein binding integral to plasma membrane cell adhesion cell surface membrane	Cell adhesion molecules (CAMs)
222853_at	-1.566	5.561	-2.869	1.159e-02	0.231	-2.814	FLRT3	fibronectin leucine rich transmembrane protein 3	20	-14252642, -14252642	N71923	23767	20p11	Hs.41296	9	receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging
225551_at	-0.865	7.161	-2.869	1.159e-02	0.231	-2.815	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	AW291187	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
218176_at	0.308	6.626	2.868	1.159e-02	0.231	-2.815	MAGEF1	melanoma antigen family F, 1	3	-185910848	NM_022149	64110	3q13	Hs.306123	4
214771_x_at	-0.342	9.344	-2.868	1.160e-02	0.231	-2.815	MPRIP	myosin phosphatase Rho interacting protein	17	16886831, 16886831	AK025604	23164	17p11.2	Hs.462341	16	actin binding protein binding cytoplasm cytoskeleton
236860_at	1.176	6.851	2.868	1.161e-02	0.231	-2.816	NPY6R	neuropeptide Y receptor Y6 (pseudogene)	5	137171360	BF968482	4888	5q31	Hs.643466 Hs.713225	4	peptide YY receptor activity receptor activity G-protein coupled receptor activity integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway membrane
1552649_a_at	-0.442	4.033	-2.867	1.161e-02	0.231	-2.817	RFFL	ring finger and FYVE-like domain containing 1	17	-30360243, -30360243	NM_057178	117584	17q12	Hs.13680	11	protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding
1553534_at	0.272	4.010	2.867	1.162e-02	0.231	-2.817	NLRP10	NLR family, pyrin domain containing 10	11	-7937731	NM_176821	338322	11p15.4	Hs.449636	6	nucleotide binding protein binding ATP binding
219804_at	-0.646	10.192	-2.867	1.163e-02	0.231	-2.818	SYNPO2L	synaptopodin 2-like	10	-75074649, -75074649	NM_024875	79933	10q22.2	Hs.645273	4	actin binding protein binding cytoplasm cytoskeleton
217754_at	-0.325	6.728	-2.867	1.163e-02	0.231	-2.818	DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	7	-44571927	NM_019082	54606	7p13	Hs.654762	16	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding nucleus nucleolus rRNA processing hydrolase activity identical protein binding
219436_s_at	0.501	6.908	2.867	1.163e-02	0.231	-2.818	EMCN	endomucin	4	-101535522	NM_016242	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
222547_at	-0.523	5.098	-2.867	1.164e-02	0.231	-2.818	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	2	101680919	AL561281	9448	2q11.2-q12	Hs.719073	22	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade transferase activity	MAPK signaling pathway
224751_at	-0.542	8.277	-2.866	1.164e-02	0.231	-2.818	PL-5283	PL-5283 protein	7	134997760	BE738276	647087	7q33	Hs.200022	3
202651_at	-0.569	6.046	-2.866	1.164e-02	0.231	-2.819	LPGAT1	lysophosphatidylglycerol acyltransferase 1	1	-209983422	NM_014873	9926	1q32	Hs.497674	6	molecular_function cytoplasm endoplasmic reticulum metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
235602_at	0.338	3.119	2.866	1.164e-02	0.231	-2.819	TP53INP1	tumor protein p53 inducible nuclear protein 1	8	-96007376	AI422387	94241	8q22	Hs.492261	16	nucleus apoptosis
213957_s_at	-0.360	5.306	-2.866	1.165e-02	0.231	-2.819	CEP350	centrosomal protein 350kDa	1	178190530	AA635523	9857	1p36.13-q41	Hs.413045	17	nucleus centrosome spindle
215942_s_at	0.343	5.282	2.866	1.165e-02	0.231	-2.819	GTSE1	G-2 and S-phase expressed 1	22	45071301	BF973178	51512	22q13.2-q13.3	Hs.386189	18	G2 phase of mitotic cell cycle molecular_function cytoplasm cytoplasmic microtubule DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest microtubule-based process	p53 signaling pathway
222764_at	0.715	5.550	2.866	1.166e-02	0.231	-2.820	ASRGL1	asparaginase like 1	11	61861349	AI928342	80150	11q12.3	Hs.535326	9	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity cytoplasm hydrolase activity asparagine catabolic process via L-aspartate	Alanine, aspartate and glutamate metabolism Cyanoamino acid metabolism Nitrogen metabolism Metabolic pathways
224861_at	-0.429	6.278	-2.866	1.166e-02	0.231	-2.820	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	9	-79525010	AA628423	2776	9q21	Hs.269782	105	nucleotide binding skeletal system development regulation of action potential GTPase activity signal transducer activity protein binding GTP binding membrane fraction cytoplasm plasma membrane plasma membrane protein amino acid ADP-ribosylation signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway activation of phospholipase C activity glutamate signaling pathway heart development blood coagulation behavior post-embryonic development neuron remodeling guanyl nucleotide binding forebrain neuron development embryonic digit morphogenesis regulation of melanocyte differentiation pigmentation during development activation of phospholipase C activity by dopamine receptor signaling pathway	Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
225612_s_at	-0.777	6.270	-2.865	1.167e-02	0.231	-2.821	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	3	184453725	BE672260	84002	3q28	Hs.718506	7	intracellular Golgi apparatus protein amino acid glycosylation multicellular organismal development central nervous system development galactosyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity lipopolysaccharide N-acetylglucosaminyltransferase activity glycolipid biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
205930_at	-0.531	6.681	-2.865	1.167e-02	0.231	-2.821	GTF2E1	general transcription factor IIE, polypeptide 1, alpha 56kDa	3	121944247	NM_005513	2960	3q21-q24	Hs.445272	41	RNA polymerase II transcription factor activity protein binding nucleus nucleoplasm transcription factor TFIIE complex transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter zinc ion binding regulation of transcription metal ion binding	Basal transcription factors
218077_s_at	-0.465	5.205	-2.865	1.167e-02	0.231	-2.821	ZDHHC3	zinc finger, DHHC-type containing 3	3	-44931757	BE542551	51304	3p21.31	Hs.61430	8	Golgi apparatus zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
210592_s_at	-0.486	7.644	-2.864	1.169e-02	0.231	-2.822	SAT1	spermidine/spermine N1-acetyltransferase 1	X	23711195	M55580	6303	Xp22.1	Hs.28491	46	diamine N-acetyltransferase activity protein binding intracellular cytoplasm metabolic process acyltransferase activity transferase activity	Arginine and proline metabolism Metabolic pathways
201713_s_at	-0.397	9.152	-2.864	1.170e-02	0.231	-2.823	RANBP2	RAN binding protein 2	2	108702368	D42063	5903	2q12.3	Hs.199561 Hs.715056	61	peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport
224333_s_at	0.450	8.570	2.864	1.170e-02	0.231	-2.823	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	AB049940	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
208741_at	-0.498	6.954	-2.863	1.171e-02	0.231	-2.824	SAP18	Sin3A-associated protein, 18kDa	13	20612652	AW274856	10284	13q12.11	Hs.524899	17	histone deacetylase complex transcription corepressor activity protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter regulation of transcription
217071_s_at	0.312	5.981	2.863	1.171e-02	0.231	-2.824	MTHFR	5,10-methylenetetrahydrofolate reductase (NADPH)	1	-11768373	AJ249275	4524	1p36.3	Hs.214142	1776	methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction	One carbon pool by folate Methane metabolism Metabolic pathways
229986_at	0.266	5.812	2.863	1.172e-02	0.231	-2.825	ZNF717	zinc finger protein 717	3	-75868718	AW205616	100131827	3p12.3	Hs.556877	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
206219_s_at	0.326	3.736	2.862	1.174e-02	0.232	-2.826	VAV1	vav 1 guanine nucleotide exchange factor	19	6723721	NM_005428	7409	19p13.2	Hs.116237	134	transcription factor activity guanyl-nucleotide exchange factor activity protein binding intracellular phagocytosis immune response integrin-mediated signaling pathway intracellular signaling cascade zinc ion binding diacylglycerol binding Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction T cell activation regulation of GTPase activity positive regulation of cell adhesion metal ion binding	Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton
209378_s_at	-0.449	6.963	-2.862	1.175e-02	0.232	-2.827	FAM190B	family with sequence similarity 190, member B	10	86078389	AI478879	54462	10q23.1	Hs.461988	5
241402_at	0.286	5.777	2.861	1.176e-02	0.232	-2.828	TSEN54	tRNA splicing endonuclease 54 homolog (S. cerevisiae)	17	71024203	AA504269	283989	17q25.1	Hs.655875	6	nucleus nucleolus tRNA splicing, via endonucleolytic cleavage and ligation mRNA processing
212762_s_at	0.461	4.482	2.861	1.176e-02	0.232	-2.828	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10	114699998	AI375916	6934	10q25.3	Hs.593995	246	blood vessel development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter anti-apoptosis cell cycle arrest beta-catenin binding transcription factor binding cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process specific transcriptional repressor activity protein kinase binding pancreas development positive regulation of insulin secretion regulation of hormone metabolic process glucose homeostasis fat cell differentiation regulation of transcription myoblast cell fate commitment Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1564536_at	0.440	7.078	2.861	1.178e-02	0.232	-2.829	ASB10	ankyrin repeat and SOCS box-containing 10	7	-150503717, -150503717	AK055536	136371	7q36.1	Hs.647081	6	intracellular signaling cascade modification-dependent protein catabolic process
1555278_a_at	-0.460	6.539	-2.860	1.178e-02	0.232	-2.830	CKAP5	cytoskeleton associated protein 5	11	-46721659	BC035554	9793	11p11.2	Hs.201253	16	gamma-tubulin complex protein binding centrosome cell cycle mitosis microtubule cytoskeleton establishment or maintenance of microtubule cytoskeleton polarity RNA transport centrosome organization spindle pole body organization cell division
204608_at	0.516	5.290	2.860	1.180e-02	0.232	-2.831	ASL	argininosuccinate lyase	7	65178210, 65178268	NM_000048	435	7cen-q11.2	Hs.632015	19	urea cycle argininosuccinate metabolic process response to hypoxia kidney development liver development argininosuccinate lyase activity cytoplasm arginine catabolic process response to nutrient locomotory behavior cellular amino acid biosynthetic process post-embryonic development lyase activity ammonia assimilation cycle arginine biosynthetic process via ornithine response to peptide hormone stimulus response to steroid hormone stimulus response to glucocorticoid stimulus response to cAMP	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Metabolic pathways
217857_s_at	-0.408	6.586	-2.859	1.181e-02	0.232	-2.832	RBM8A	RNA binding motif protein 8A	1	144218994	NM_005105	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
1564190_x_at	0.431	4.303	2.859	1.182e-02	0.232	-2.832	ZNF519	zinc finger protein 519	18	-14094723	AK096748	162655	18p11.21	Hs.352635	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212189_s_at	-0.467	7.333	-2.859	1.182e-02	0.232	-2.832	COG4	component of oligomeric golgi complex 4	16	-69071972	AK022874	25839	16q22.1	Hs.208680	11	protein binding Golgi apparatus protein transport membrane Golgi transport complex
226635_at	-0.621	7.121	-2.859	1.182e-02	0.232	-2.832	LOC401504	hypothetical gene supported by AK091718	9		BG170478	401504	9p13.2	Hs.446271	2
208926_at	-0.409	6.480	-2.859	1.182e-02	0.232	-2.833	NEU1	sialidase 1 (lysosomal sialidase)	6	-31934807, -3273082, -3074566	U84246	4758	6p21.3	Hs.520037	41	exo-alpha-sialidase activity protein binding plasma membrane metabolic process hydrolase activity, acting on glycosyl bonds cytoplasmic vesicle lysosomal lumen	Other glycan degradation Sphingolipid metabolism Lysosome
204663_at	0.351	7.408	2.857	1.185e-02	0.232	-2.835	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	11	-85829799, -85829797, -85829797	NM_006680	10873	11cen-q22.3	Hs.199743	8	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity mitochondrion mitochondrial matrix pyruvate metabolic process malate metabolic process oxygen and reactive oxygen species metabolic process aerobic respiration oxidoreductase activity metal ion binding cofactor binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways
222924_at	-0.800	7.669	-2.857	1.186e-02	0.232	-2.835	SLMAP	sarcolemma associated protein	3	57718213	BF526855	7871	3p21.2-p14.3	Hs.476432	11	smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding
241393_at	0.448	6.009	2.857	1.186e-02	0.232	-2.835	IPP	intracisternal A particle-promoted polypeptide	1	-45936995, -45932586	R78604	3652	1p34-p32	Hs.699548	8	actin binding protein binding cytoplasm actin cytoskeleton
203038_at	-0.359	6.589	-2.857	1.186e-02	0.232	-2.835	PTPRK	protein tyrosine phosphatase, receptor type, K	6	-128331617, -128331617	NM_002844	5796	6q22.2-q22.3	Hs.155919	20	receptor activity transmembrane receptor protein tyrosine phosphatase activity plasma membrane integral to plasma membrane cell-cell junction adherens junction protein amino acid dephosphorylation cell adhesion signal transduction transforming growth factor beta receptor signaling pathway beta-catenin binding cell surface negative regulation of keratinocyte proliferation negative regulation of transcription hydrolase activity protein kinase binding negative regulation of cell migration leading edge membrane protein localization at cell surface cellular response to reactive oxygen species cellular response to UV gamma-catenin binding negative regulation of cell cycle focal adhesion formation
208817_at	-0.524	7.854	-2.857	1.186e-02	0.232	-2.836	COMT	catechol-O-methyltransferase	22	18309262, 18318459, 18319044, 18330069	BC000419	1312	22q11.21 22q11.21-q11.23	Hs.370408 Hs.704514 Hs.713616	742	magnesium ion binding protein binding soluble fraction cytoplasm microsome cytosol plasma membrane catecholamine metabolic process integral to membrane catechol O-methyltransferase activity catechol O-methyltransferase activity transferase activity neurotransmitter catabolic process dopamine catabolic process	Tyrosine metabolism Betalain biosynthesis Metabolic pathways
229872_s_at	-1.334	6.025	-2.857	1.186e-02	0.232	-2.836	LOC100132999	hypothetical protein LOC100132999	1		AA532655	100132999	1q21.2	Hs.670106
222692_s_at	-0.522	5.378	-2.857	1.188e-02	0.233	-2.837	FNDC3B	fibronectin type III domain containing 3B	3	173240111, 173241037	BF444916	64778	3q26.31	Hs.159430	9	endoplasmic reticulum membrane integral to membrane
225425_s_at	0.550	9.587	2.856	1.189e-02	0.233	-2.838	MRPL41	mitochondrial ribosomal protein L41	9	139566129	AV726260	64975	9q34.3	Hs.44017	10	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation apoptosis cell cycle
240110_at	0.636	4.433	2.856	1.190e-02	0.233	-2.838	HMGCS2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	1	-120092525	AI090874	3158	1p13-p12	Hs.59889	13	hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity mitochondrion mitochondrial inner membrane mitochondrial matrix cholesterol biosynthetic process response to nutrient metabolic process isoprenoid biosynthetic process transferase activity response to drug response to peptide hormone stimulus	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
231801_at	0.298	4.291	2.856	1.190e-02	0.233	-2.838	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	20	-49441172, -49441171	AL035682	4773	20q13.2-q13.3	Hs.713650	93	cytokine production transcription factor activity protein binding nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription activator activity sequence-specific DNA binding positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter	MAPK signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
213145_at	-0.387	5.728	-2.855	1.191e-02	0.233	-2.839	FBXL14	F-box and leucine-rich repeat protein 14	12	-1545420	BF001666	144699	12p13.33	Hs.367956	3	modification-dependent protein catabolic process
204175_at	-0.608	7.909	-2.855	1.192e-02	0.233	-2.840	ZNF593	zinc finger protein 593	1	26368974	NM_015871	51042	1p36.11	Hs.477273	6	negative regulation of transcription from RNA polymerase II promoter DNA binding transcription corepressor activity intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
218082_s_at	-0.404	7.293	-2.854	1.193e-02	0.233	-2.841	UBP1	upstream binding protein 1 (LBP-1a)	3	-33404831, -33404831	NM_014517	7342	3p22.3	Hs.643744	11	transcription factor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter negative regulation of transcription specific transcriptional repressor activity viral genome replication
203589_s_at	-0.601	5.744	-2.854	1.194e-02	0.233	-2.842	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	NM_006286	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
203582_s_at	-0.396	7.410	-2.854	1.195e-02	0.233	-2.842	RAB4A	RAB4A, member RAS oncogene family	1	227473501	NM_004578	5867	1q42-q43	Hs.296169	43	nucleotide binding GTPase activity GTP binding cytoplasm small GTPase mediated signal transduction protein transport membrane	Endocytosis
200978_at	0.369	12.281	2.853	1.196e-02	0.233	-2.843	MDH1	malate dehydrogenase 1, NAD (soluble)	2	63669625	NM_005917	4190	2p13.3	Hs.526521	18	malic enzyme activity binding soluble fraction cytoplasm cytosol cytosol glycolysis tricarboxylic acid cycle oxaloacetate metabolic process malate metabolic process oxidoreductase activity NAD metabolic process L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
202376_at	0.964	5.401	2.853	1.197e-02	0.233	-2.844	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	14	94148466	NM_001085	12	14q32.1	Hs.534293 Hs.710488	134	DNA binding serine-type endopeptidase inhibitor activity protein binding extracellular region intracellular nucleus acute-phase response inflammatory response regulation of lipid metabolic process peptidase inhibitor activity
1555575_a_at	-0.261	9.171	-2.852	1.199e-02	0.233	-2.845	KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	19	-53577638	BC008958	10945	19q13.3	Hs.515515	14	receptor activity KDEL sequence binding protein binding membrane fraction endoplasmic reticulum ER-Golgi intermediate compartment protein retention in ER lumen intracellular protein transport membrane integral to membrane vesicle-mediated transport	Vibrio cholerae infection
215040_at	0.426	6.661	2.852	1.199e-02	0.233	-2.845	RNASEH2B	ribonuclease H2, subunit B	13	50381892, 50381892	AL049218	79621	13q14.3	Hs.306291	13	nucleus	DNA replication
205657_at	0.287	6.751	2.852	1.199e-02	0.233	-2.846	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	2	-42847732	NM_012205	23498	2p21	Hs.368805	12	3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity soluble fraction cytoplasm cytosol cytosol ferrous iron binding electron carrier activity response to zinc ion oxidoreductase activity pyridine nucleotide biosynthetic process NAD metabolic process quinolinate biosynthetic process response to cadmium ion metal ion binding oxidation reduction neuron maintenance	Tryptophan metabolism Metabolic pathways
207685_at	0.316	5.628	2.852	1.199e-02	0.233	-2.846	CRYBB3	crystallin, beta B3	22	23925824	NM_004076	1417	22q11.2-q12.1 22q11.23	Hs.533022	12	structural constituent of eye lens protein binding visual perception
202717_s_at	-0.672	6.828	-2.851	1.200e-02	0.233	-2.846	CDC16	cell division cycle 16 homolog (S. cerevisiae)	13	114018463	NM_003903	8881	13q34	Hs.374127	32	binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
200610_s_at	-0.358	9.937	-2.851	1.200e-02	0.233	-2.846	NCL	nucleolin	2	-232027702	NM_005381	4691	2q12-qter	Hs.79110	97	nucleotide binding angiogenesis DNA binding RNA binding nucleus nucleolus cell cortex protein C-terminus binding ribonucleoprotein complex telomeric DNA binding	Pathogenic Escherichia coli infection - EHEC
227340_s_at	0.926	5.307	2.851	1.201e-02	0.234	-2.847	RGMB	RGM domain family, member B	5	98132898	AL117590	285704	5q15	Hs.526902	5	ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane
230068_s_at	0.303	3.912	2.850	1.204e-02	0.234	-2.849	PEG3	paternally expressed 3	19	-62013256, -62013256	W93046	5178	19q13.4	Hs.719209	18	nucleic acid binding transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent apoptosis zinc ion binding metal ion binding
206319_s_at	0.229	3.208	2.850	1.204e-02	0.234	-2.849	SPINLW1	serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)	20	-43602678, -43602678	AF286368	57119	20q12-q13.2	Hs.121084	10	serine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity
236073_at	0.292	5.254	2.850	1.204e-02	0.234	-2.849	EPHA10	EPH receptor A10	1	-37998531, -37954232	AA789266	284656	1p34.3	Hs.129435	5	nucleotide binding receptor activity ephrin receptor activity ATP binding extracellular region plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane transferase activity
205161_s_at	0.612	5.494	2.850	1.204e-02	0.234	-2.849	PEX11A	peroxisomal biogenesis factor 11 alpha	15	-88027290	NM_003847	8800	15q26.1	Hs.31034	9	peroxisome peroxisomal membrane integral to peroxisomal membrane signal transduction membrane integral to membrane peroxisome fission
209748_at	-0.482	6.626	-2.849	1.205e-02	0.234	-2.850	SPAST	spastin	2	32142183	AB029006	6683	2p24-p21	Hs.468091	90	nucleotide binding microtubule bundle formation ATP binding ATP binding nucleus nucleus cytoplasm endosome endoplasmic reticulum centrosome spindle microtubule ER to Golgi vesicle-mediated transport cell cycle cytokinesis, completion of separation multicellular organismal development nervous system development microtubule binding microtubule binding cell death microtubule-severing ATPase activity membrane integral to membrane hydrolase activity nucleoside-triphosphatase activity cell differentiation midbody protein hexamerization ATPase activity, uncoupled alpha-tubulin binding perinuclear region of cytoplasm beta-tubulin binding microtubule severing protein homooligomerization cell division
201807_at	-0.346	8.724	-2.848	1.207e-02	0.234	-2.852	VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)	10	70553913	NM_004896	9559	10q21.1	Hs.499925	17	protein binding cytoplasm endosome cytosol vacuolar transport protein transporter activity protein transport membrane retromer complex retrograde transport, endosome to Golgi
228891_at	-0.644	8.904	-2.848	1.209e-02	0.234	-2.853	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	9	-91181971, -91165525	N93399	10507	9q22.2	Hs.494406	29	receptor activity receptor binding anti-apoptosis immune response cell adhesion multicellular organismal development nervous system development membrane integral to membrane cell differentiation positive regulation of axonogenesis	Axon guidance
225293_at	0.627	7.295	2.847	1.210e-02	0.234	-2.853	COL27A1	collagen, type XXVII, alpha 1	9	115958051	AK021957	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
1553096_s_at	0.354	5.273	2.847	1.211e-02	0.234	-2.854	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2	111594961, 111594961	NM_138627	10018	2q13	Hs.469658	143	peripheral to membrane of membrane fraction in utero embryonic development B cell homeostasis B cell apoptosis kidney development myeloid cell homeostasis protein binding cytoplasm mitochondrion mitochondrial outer membrane cytosol plasma membrane induction of apoptosis cell-matrix adhesion spermatogenesis microtubule binding male gonad development activation of pro-apoptotic gene products post-embryonic development mammary gland development tube lumen formation odontogenesis of dentine-containing tooth T cell homeostasis ear development regulation of organ growth regulation of pigmentation during development spleen development thymus development post-embryonic organ morphogenesis
202636_at	-0.484	7.437	-2.846	1.212e-02	0.235	-2.855	RNF103	ring finger protein 103	2	-86684026	NM_005667	7844	2p11.2	Hs.469199	9	protein binding central nervous system development zinc ion binding membrane integral to membrane metal ion binding
221912_s_at	0.644	8.726	2.846	1.213e-02	0.235	-2.855	CCDC28B	coiled-coil domain containing 28B	1	32438788	AL049795	79140	1p35.1	Hs.718470	10
203633_at	0.653	7.024	2.846	1.213e-02	0.235	-2.856	CPT1A	carnitine palmitoyltransferase 1A (liver)	11	-68278926, -68278663	BF001714	1374	11q13.1-q13.2	Hs.503043	32	carnitine O-palmitoyltransferase activity mitochondrion mitochondrial outer membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport acyltransferase activity membrane integral to membrane transferase activity	Fatty acid metabolism PPAR signaling pathway Adipocytokine signaling pathway
207622_s_at	-0.472	6.421	-2.845	1.215e-02	0.235	-2.857	ABCF2	ATP-binding cassette, sub-family F (GCN20), member 2	7	-150540508, -150535855	NM_005692	10061	7q36	Hs.654958	15	nucleotide binding transporter activity ATP binding mitochondrial envelope transport ATPase activity ATP-binding cassette (ABC) transporter complex
225369_at	0.302	5.837	2.845	1.216e-02	0.235	-2.858	ESAM	endothelial cell adhesion molecule	11	-124128228	AL573851	90952	11q24.2	Hs.173840	11	protein binding plasma membrane adherens junction tight junction homophilic cell adhesion integral to membrane cell junction	Cell adhesion molecules (CAMs) Leukocyte transendothelial migration
203511_s_at	0.400	7.452	2.845	1.216e-02	0.235	-2.858	TRAPPC3	trafficking protein particle complex 3	1	-36374759	AF041432	27095	1p34.3	Hs.523131	16	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol ER to Golgi vesicle-mediated transport vesicle-mediated transport TRAPP complex
213005_s_at	-0.349	8.042	-2.845	1.217e-02	0.235	-2.858	KANK1	KN motif and ankyrin repeat domains 1	9	494702, 696895	D79994	23189	9p24.3	Hs.306764	14	cytoplasm
224735_at	-0.394	6.439	-2.844	1.217e-02	0.235	-2.859	CYBASC3	cytochrome b, ascorbate dependent 3	11	-60872797, -60872797	AA683481	220002	11q12.2	Hs.22546	8	iron ion binding lysosome endosome transport membrane integral to membrane oxidoreductase activity electron transport chain metal ion binding
201854_s_at	-0.552	7.057	-2.844	1.219e-02	0.235	-2.860	ATMIN	ATM interactor	16	79626958	AI744148	23300	16q23.2	Hs.16349 Hs.589959	9	intracellular nucleus response to DNA damage stimulus zinc ion binding metal ion binding
201957_at	-0.494	8.875	-2.844	1.219e-02	0.235	-2.860	PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B	1	200584458, 200698493	AF324888	4660	1q32.1	Hs.444403	14	cytoplasm regulation of muscle contraction signal transduction enzyme activator activity	Vascular smooth muscle contraction
242584_at	0.775	5.343	2.844	1.219e-02	0.235	-2.860	FAM161A	family with sequence similarity 161, member A	2	-61905486	AI954412	84140	2p15	Hs.440466	7
241601_at	-0.518	5.930	-2.844	1.219e-02	0.235	-2.860	WIPF3	WAS/WASL interacting protein family, member 3	7	29840865	H58488	644150	7p14.3	Hs.709280	5	actin binding cytoplasm multicellular organismal development spermatogenesis cell differentiation
202804_at	-0.576	7.373	-2.843	1.220e-02	0.235	-2.861	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	16	15950934	AI539710	4363	16p13.1	Hs.709181	163	nucleotide binding transporter activity ATP binding membrane fraction plasma membrane integral to plasma membrane transport hydrolase activity ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances	ABC transporters
1554868_s_at	-0.901	7.913	-2.843	1.220e-02	0.235	-2.861	PCNP	PEST proteolytic signal containing nuclear protein	3	102775731	BC013916	57092	3q12.3	Hs.545311 Hs.654949	6	protein binding nucleus cell cycle protein ubiquitination proteasomal ubiquitin-dependent protein catabolic process
217595_at	-0.319	2.713	-2.843	1.220e-02	0.235	-2.861	GSPT1	G1 to S phase transition 1	16	-11869485, -11869485	AV701723	2935	16p13.1	Hs.528780	27	G1/S transition of mitotic cell cycle nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translation release factor activity GTPase activity protein binding GTP binding intracellular translation protein amino acid methylation
227796_at	-0.413	6.329	-2.843	1.220e-02	0.235	-2.861	ZFP62	zinc finger protein 62 homolog (mouse)	5	-180207218, -12668	AW157773	643836	5q35.3	Hs.509227 Hs.719290	6	nucleic acid binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
42361_g_at	0.492	4.416	2.843	1.221e-02	0.235	-2.861	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AI588986	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
205569_at	0.704	4.122	2.842	1.222e-02	0.235	-2.862	LAMP3	lysosomal-associated membrane protein 3	3	-184322696	NM_014398	27074	3q26.3-q27	Hs.518448	13	lysosomal membrane cell proliferation membrane integral to membrane	Lysosome
212926_at	-0.589	4.594	-2.842	1.222e-02	0.235	-2.863	SMC5	structural maintenance of chromosomes 5	9	72063697	AW183677	23137	9q21.12	Hs.534189 Hs.601181	13	nucleotide binding ATP binding nucleus chromosome DNA repair DNA recombination response to DNA damage stimulus
211947_s_at	-0.378	4.975	-2.842	1.223e-02	0.235	-2.863	BAT2D1	BAT2 domain containing 1	1	169721289	AI359472	23215	1q23.3	Hs.494614	5
1556560_a_at	0.273	5.406	2.842	1.224e-02	0.235	-2.864	LOC100128071	similar to hCG41624	1		BI825578	100128071	1p35.1	Hs.660539	1
204113_at	-0.646	4.814	-2.842	1.224e-02	0.235	-2.864	CUGBP1	CUG triplet repeat, RNA binding protein 1	11	-47446520, -47446520, -47446520	NM_006560	10658	11p11	Hs.632137	34	nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding
210875_s_at	-0.892	6.856	-2.842	1.224e-02	0.235	-2.864	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	U12170	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
204286_s_at	-0.917	3.439	-2.841	1.225e-02	0.235	-2.865	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	18	55718171	NM_021127	5366	18q21.32	Hs.96	36	release of cytochrome c from mitochondria protein binding mitochondrion induction of apoptosis activation of caspase activity cell structure disassembly during apoptosis virus-infected cell apoptosis response to dsRNA	p53 signaling pathway
209682_at	-0.469	6.375	-2.841	1.225e-02	0.235	-2.865	CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	3	-106859798	U26710	868	3q13.11	Hs.430589	44	signal transducer activity calcium ion binding protein binding nucleus cytoplasm NLS-bearing substrate import into nucleus immune response cell surface receptor linked signal transduction zinc ion binding ligase activity modification-dependent protein catabolic process	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis Jak-STAT signaling pathway T cell receptor signaling pathway Insulin signaling pathway Pathways in cancer Chronic myeloid leukemia
229068_at	-0.533	5.555	-2.841	1.226e-02	0.235	-2.865	CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	5	10303281	BF197357	22948	5p15.2	Hs.1600	30	nucleotide binding ATP binding nucleus nucleolus cytoplasm chaperonin-containing T-complex protein folding unfolded protein binding
227144_at	-0.575	5.835	-2.841	1.226e-02	0.235	-2.865	C22orf9	chromosome 22 open reading frame 9	22	-43966786, -43966786	AA476916	23313	22q13.31	Hs.592207	10	protein binding
224738_x_at	-0.388	8.355	-2.841	1.226e-02	0.235	-2.865	RPL7L1	ribosomal protein L7-like 1	6	42955648	BE858199	285855	6p21.1	Hs.520133	5	structural constituent of ribosome protein binding intracellular ribosome translation large ribosomal subunit transcription regulator activity
235463_s_at	-0.769	4.215	-2.840	1.228e-02	0.235	-2.867	LASS6	LAG1 homolog, ceramide synthase 6	2	169021080	AI081356	253782	2q24.3	Hs.506829 Hs.718403	5	transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding ceramide biosynthetic process sphingosine N-acyltransferase activity
203880_at	-0.355	10.231	-2.840	1.229e-02	0.235	-2.868	COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	3	-120871061	NM_005694	10063	3q13.33	Hs.534383	19	cytoplasm mitochondrion mitochondrial intermembrane space generation of precursor metabolites and energy copper ion transport copper chaperone activity metal ion binding	Oxidative phosphorylation Metabolic pathways
216942_s_at	-0.444	5.244	-2.839	1.230e-02	0.235	-2.869	CD58	CD58 molecule	1	-116862845, -116858679	D28586	965	1p13	Hs.34341	38	protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane	Cell adhesion molecules (CAMs)
1553106_at	-0.600	2.812	-2.839	1.232e-02	0.235	-2.870	C5orf24	chromosome 5 open reading frame 24	5	134209268, 134209556	NM_152409	134553	5q31.1	Hs.406549	3
221649_s_at	-0.268	6.484	-2.838	1.233e-02	0.236	-2.871	PPAN	peter pan homolog (Drosophila)	19	10077964	BC000535	56342	19p13	Hs.14468	15	protein binding nucleus nucleolus RNA splicing
200798_x_at	-0.785	6.800	-2.837	1.236e-02	0.236	-2.873	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	1	-148813658	NM_021960	4170	1q21	Hs.719112	154	cell fate determination protein binding nucleus nucleoplasm cytoplasm mitochondrion mitochondrial outer membrane anti-apoptosis multicellular organismal development protein channel activity membrane integral to membrane cellular homeostasis cell differentiation response to cytokine stimulus regulation of apoptosis protein heterodimerization activity
204711_at	0.305	5.867	2.837	1.237e-02	0.236	-2.873	KIAA0753	KIAA0753	17	-6422368	NM_014804	9851	17p13.2-p13.1	Hs.28070	3
201534_s_at	-0.532	7.049	-2.836	1.237e-02	0.236	-2.874	UBL3	ubiquitin-like 3	13	-29236545	AF044221	5412	13q12-q13	Hs.145575	12	intracellular plasma membrane
202879_s_at	0.299	5.344	2.836	1.238e-02	0.236	-2.874	CYTH1	cytohesin 1	17	-74181724	AI798823	9267	17q25	Hs.191215	28	ARF guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm plasma membrane vesicle-mediated transport regulation of cell adhesion regulation of ARF protein signal transduction
229139_at	-0.822	10.879	-2.836	1.238e-02	0.236	-2.874	JPH1	junctophilin 1	8	-75309492	AI202201	56704	8q21	Hs.657367	9	molecular_function microsome plasma membrane muscle organ development structural constituent of muscle junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc junctional membrane complex regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
208945_s_at	-0.502	8.493	-2.836	1.238e-02	0.236	-2.874	BECN1	beclin 1, autophagy related	17	-38215675	NM_003766	8678	17q21	Hs.716464	56	protein binding cytoplasm Golgi apparatus trans-Golgi network autophagy anti-apoptosis cellular defense response negative regulation of cell proliferation response to virus membrane cytoplasmic membrane-bounded vesicle positive regulation of macroautophagy protein complex	Regulation of autophagy
222851_at	-0.510	4.566	-2.836	1.238e-02	0.236	-2.874	ZNF654	zinc finger protein 654	3	88270951	AL120354	55279	3p11.1	Hs.591650 Hs.661116	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225564_at	0.471	5.002	2.836	1.239e-02	0.236	-2.875	SPATA13	spermatogenesis associated 13	13	23632886	AW269397	221178	13q12.12	Hs.657121	7	Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
222507_s_at	-0.802	7.252	-2.835	1.240e-02	0.236	-2.876	TMEM9B	TMEM9 domain family, member B	11	-8925415	AI188389	56674	11p15.3	Hs.501853	7	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
229241_at	0.366	6.996	2.835	1.241e-02	0.236	-2.876	LDHD	lactate dehydrogenase D	16	-73703258	AI623801	197257	16q23.1	Hs.380929	5	D-lactate dehydrogenase (cytochrome) activity protein binding protein binding mitochondrion oxidoreductase activity FAD binding oxidation reduction	Pyruvate metabolism
221753_at	-0.387	5.727	-2.835	1.241e-02	0.236	-2.876	SSH1	slingshot homolog 1 (Drosophila)	12	-107709824, -107709824, -107700595	AI651213	54434	12q24.11	Hs.199763	23	cell morphogenesis actin binding protein tyrosine phosphatase activity protein binding cytoplasm cytoskeleton plasma membrane protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity lamellipodium actin cytoskeleton organization	Regulation of actin cytoskeleton
1557450_s_at	0.326	7.313	2.834	1.243e-02	0.236	-2.878	WHAMML2	WAS protein homolog associated with actin, golgi membranes and microtubules-like 2 (pseudogene)	15	26781769	AF129926	440253	15q13.1	Hs.558967 Hs.655308	3
226612_at	-0.792	8.605	-2.834	1.243e-02	0.236	-2.878	FLJ25076	probable ubiquitin-conjugating enzyme E2 FLJ25076	5	6501735	H17038	134111	5p15.31	Hs.126856	3	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
215120_s_at	-0.627	4.795	-2.834	1.244e-02	0.236	-2.879	SAMD4A	sterile alpha motif domain containing 4A	14	54104386, 54291255	BF697247	23034	14q22.2	Hs.98259	4	cytoplasm synaptosome translation repressor activity dendrite positive regulation of translation
217555_at	-0.366	5.076	-2.834	1.244e-02	0.236	-2.879	SMC1A	structural maintenance of chromosomes 1A	X	-53417794	AI042030	8243	Xp11.22-p11.21	Hs.211602	47	cell cycle checkpoint nucleotide binding nuclear mRNA splicing, via spliceosome condensed chromosome kinetochore condensed nuclear chromosome chromatin binding microtubule motor activity protein binding ATP binding nucleus chromosome cytoplasm DNA repair response to DNA damage stimulus cell cycle mitotic spindle organization mitotic sister chromatid cohesion meiosis cohesin core heterodimer response to radiation DNA damage response, signal transduction protein heterodimerization activity chromosome organization cell division	Cell cycle
210965_x_at	0.333	3.294	2.833	1.245e-02	0.236	-2.879	CDC2L5	cell division cycle 2-like 5 (cholinesterase-related cell division controller)	7	39956483	BC001274	8621	7p13	Hs.233552	18	nucleotide binding cyclin-dependent protein kinase activity ATP binding protein amino acid phosphorylation regulation of mitosis multicellular organismal development positive regulation of cell proliferation transferase activity
1564224_x_at	0.363	4.679	2.833	1.245e-02	0.236	-2.879	UNQ2963	hypothetical LOC283314	12	7152179	AK091792	283314	12p13.31	Hs.715709	2
225547_at	-0.604	10.993	-2.833	1.247e-02	0.236	-2.880	SNHG6	small nucleolar RNA host gene 6 (non-protein coding)	8	-67996718	BG169443	641638	8q13	Hs.372680	1
202242_at	-0.595	9.102	-2.832	1.248e-02	0.236	-2.881	TSPAN7	tetraspanin 7	X	38305674	NM_004615	7102	Xp11.4	Hs.441664	18	plasma membrane integral to plasma membrane protein amino acid N-linked glycosylation
235305_s_at	0.497	7.354	2.832	1.248e-02	0.236	-2.881	ECHDC2	enoyl Coenzyme A hydratase domain containing 2	1	-53134491	AI903313	55268	1p32.3	Hs.476319	2	mitochondrion lipid metabolic process fatty acid metabolic process metabolic process lyase activity
1553363_at	0.335	4.519	2.832	1.248e-02	0.236	-2.882	C6orf195	chromosome 6 open reading frame 195	6	-2567970	NM_152554	154386	6p25.2	Hs.680574	4
203256_at	0.415	5.599	2.831	1.250e-02	0.237	-2.883	CDH3	cadherin 3, type 1, P-cadherin (placental)	16	67235651	NM_001793	1001	16q22.1	Hs.191842	56	calcium ion binding protein binding plasma membrane cell-cell adherens junction homophilic cell adhesion visual perception integral to membrane response to stimulus	Cell adhesion molecules (CAMs)
208205_at	0.330	4.128	2.831	1.252e-02	0.237	-2.884	PCDHA9	protocadherin alpha 9	5	140207540, 140207540	NM_014005	9752	5q31	Hs.199343	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
202950_at	-0.425	7.774	-2.831	1.252e-02	0.237	-2.884	CRYZ	crystallin, zeta (quinone reductase)	1	-74943762, -74943759	NM_001889	1429	1p31-p22	Hs.83114	14	NADPH:quinone reductase activity binding cytoplasm visual perception zinc ion binding oxidoreductase activity oxidation reduction
229229_at	0.469	4.802	2.830	1.252e-02	0.237	-2.884	AGXT2	alanine-glyoxylate aminotransferase 2	5	-35033962	AJ292204	64902	5p13	Hs.34494	7	mitochondrion alanine-glyoxylate transaminase activity transferase activity pyridoxal phosphate binding (R)-3-amino-2-methylpropionate-pyruvate transaminase activity	Alanine, aspartate and glutamate metabolism
1560105_at	0.487	3.936	2.830	1.254e-02	0.237	-2.886	PTPRB	protein tyrosine phosphatase, receptor type, B	12	-69196898, -69196898	BC043182	5787	12q15-q21	Hs.434375	29	transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation membrane hydrolase activity	Adherens junction
210878_s_at	-0.460	8.178	-2.830	1.255e-02	0.237	-2.886	KDM3B	lysine (K)-specific demethylase 3B	5	137716183	BC001202	51780	5q31	Hs.714832	14	iron ion binding nucleus nucleolus zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
222985_at	-0.310	11.964	-2.829	1.255e-02	0.237	-2.887	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	7	-75794043	AB024334	7532	7q11.23	Hs.520974	56	protein kinase C binding insulin-like growth factor receptor binding cytoplasm negative regulation of protein kinase activity protein targeting protein kinase C inhibitor activity regulation of signal transduction protein domain specific binding regulation of neuron differentiation regulation of synaptic plasticity	Cell cycle Neurotrophin signaling pathway
1557044_at	0.316	2.374	2.829	1.256e-02	0.237	-2.887	LOC100127980	hypothetical protein LOC100127980	19		BC041949	100127980	19q13.12	Hs.595153	1
202579_x_at	-0.802	8.373	-2.829	1.256e-02	0.237	-2.887	HMGN4	high mobility group nucleosomal binding domain 4	6	26646550	NM_006353	10473	6p21.3	Hs.236774	6	chromatin DNA binding nucleus
204931_at	0.473	3.536	2.829	1.257e-02	0.237	-2.888	TCF21	transcription factor 21	6	134251951, 134251952	NM_003206	6943	6pter-qter	Hs.78061	16	branching involved in ureteric bud morphogenesis DNA binding protein binding nucleus mesoderm development sex differentiation organ morphogenesis transcription regulator activity regulation of transcription
208352_x_at	0.471	11.108	2.828	1.258e-02	0.237	-2.889	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_020479	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
208875_s_at	-0.641	6.061	-2.828	1.258e-02	0.237	-2.889	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	3	197951124	BF796470	5062	3q29	Hs.518530	80	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol negative regulation of protein kinase activity apoptosis signal transduction membrane transferase activity regulation of growth identical protein binding interspecies interaction between organisms protein amino acid autophosphorylation perinuclear region of cytoplasm	MAPK signaling pathway ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
212137_at	-0.345	9.074	-2.828	1.259e-02	0.237	-2.889	LARP1	La ribonucleoprotein domain family, member 1	5	154072654, 154115081	AV746402	23367	5q33.2	Hs.292078	11	RNA binding protein binding
217187_at	0.468	6.696	2.828	1.259e-02	0.237	-2.889	MUC5AC	mucin 5AC, oligomeric mucus/gel-forming	11	1132473	Z34282	4586	11p15.5	Hs.534332 Hs.558950	95	molecular_function protein binding extracellular region apoptosis induction of apoptosis cell adhesion digestion biological_process negative regulation of cell proliferation extracellular matrix constituent, lubricant activity negative regulation of cell migration fibril fibril organization
225155_at	-1.054	11.077	-2.827	1.260e-02	0.237	-2.890	SNHG5	small nucleolar RNA host gene 5 (non-protein coding)	6	-86443443	BG339050	387066	6q14.3	Hs.292457	2
1555379_at	0.315	4.048	2.826	1.263e-02	0.238	-2.892	FAM159A	family with sequence similarity 159, member A	1	52871653	BC041608	348378	1p32.3	Hs.424589	2	membrane integral to membrane
208873_s_at	-0.469	9.513	-2.826	1.265e-02	0.238	-2.893	REEP5	receptor accessory protein 5	5	-112239979	BC000232	7905	5q22-q23	Hs.429608	11	molecular_function protein binding biological_process membrane integral to membrane
210401_at	0.722	6.348	2.825	1.266e-02	0.238	-2.894	P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	17	-3746633	U45448	5023	17p13.3	Hs.41735	42	purinergic nucleotide receptor activity serotonin secretion by platelet regulation of vascular smooth muscle contraction receptor activity ATP-gated cation channel activity calcium channel activity protein binding ATP binding plasma membrane plasma membrane integral to plasma membrane activation of caspase activity signal transduction insemination regulation of blood pressure death synaptosome platelet activation external side of cell outer membrane response to ATP synaptic transmission, glutamatergic vasoconstriction protein homodimerization activity positive regulation of ion transport membrane raft postsynaptic membrane ceramide biosynthetic process protein heterodimerization activity response to stimulus regulation of calcium ion transport	Calcium signaling pathway Neuroactive ligand-receptor interaction
201383_s_at	-0.802	6.963	-2.825	1.267e-02	0.238	-2.895	NBR1	neighbor of BRCA1 gene 1	17	38576023, 38576036, 38576771	AL044170	4077	17q21.31	Hs.277721 Hs.373818 Hs.546264 Hs.708158	16	zinc ion binding metal ion binding
223247_at	-0.333	6.851	-2.824	1.268e-02	0.238	-2.895	MED10	mediator complex subunit 10	5	-6425038	BC003353	84246	5p15.31	Hs.13885	12	nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity regulation of transcription
223124_s_at	-0.460	8.444	-2.824	1.268e-02	0.238	-2.896	C1orf128	chromosome 1 open reading frame 128	1	23977462	AF271784	57095	1p36.11	Hs.31819	4
206355_at	-1.324	5.808	-2.824	1.269e-02	0.238	-2.896	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18	11679135, 11741561	R20102	2774	18p11.22-p11.21	Hs.136295	16	nucleotide binding GTPase activity signal transducer activity GTP binding signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding	Calcium signaling pathway Olfactory transduction
205981_s_at	-0.798	6.685	-2.824	1.269e-02	0.238	-2.897	ING2	inhibitor of growth family, member 2	4	184663213	NM_001564	3622	4q35.1	Hs.107153	27	DNA binding chromatin binding protein binding nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding transcription activator activity chromatin modification Sin3 complex CCAAT-binding factor complex regulation of growth positive regulation of transcription metal ion binding
200045_at	-0.438	8.182	-2.824	1.270e-02	0.238	-2.897	ABCF1	ATP-binding cassette, sub-family F (GCN20), member 1	6	30647148, 1987727, 1786022	NM_001090	23	6p21.33	Hs.655285	15	nucleotide binding ATP binding translation inflammatory response translation factor activity, nucleic acid binding ATPase activity ATPase activity, coupled to transmembrane movement of substances
1567250_at	0.305	2.951	2.824	1.270e-02	0.238	-2.897	OR10A3	olfactory receptor, family 10, subfamily A, member 3	11	-7916698	X64986	26496	11p15.4	Hs.381322	5	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
229573_at	-0.640	6.310	-2.823	1.270e-02	0.238	-2.897	USP9X	ubiquitin specific peptidase 9, X-linked	X	40829831	AI659456	8239	Xp11.4	Hs.77578	24	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm ubiquitin-dependent protein catabolic process transforming growth factor beta receptor signaling pathway female gamete generation peptidase activity protein deubiquitination BMP signaling pathway co-SMAD binding
228301_x_at	0.466	10.761	2.823	1.271e-02	0.238	-2.898	NDUFB10	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa	16	1949517	AA854479	4716	16p13.3	Hs.513266	11	protein binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
244572_at	0.831	7.073	2.822	1.274e-02	0.238	-2.900	KY	kyphoscoliosis peptidase	3	-135801454	AI147310	339855	3q22.2	Hs.146730	4	cytoplasm cytoskeleton peptidase activity
208696_at	-0.424	8.894	-2.822	1.274e-02	0.238	-2.900	CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	5	10303281	AF275798	22948	5p15.2	Hs.1600	30	nucleotide binding ATP binding nucleus nucleolus cytoplasm chaperonin-containing T-complex protein folding unfolded protein binding
203610_s_at	-0.643	4.839	-2.822	1.275e-02	0.239	-2.901	TRIM38	tripartite motif-containing 38	6	26071049	AI363270	10475	6p21.3	Hs.584851	7	signal transducer activity protein binding cellular_component intracellular zinc ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
218127_at	-0.765	7.185	-2.821	1.276e-02	0.239	-2.901	NFYB	nuclear transcription factor Y, beta	12	-103034987	AI804118	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
210104_at	-0.392	6.849	-2.820	1.279e-02	0.239	-2.903	MED6	mediator complex subunit 6	14	-70120709	AF074723	10001	14q24.2	Hs.497353	22	RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter
1565661_x_at	0.388	5.480	2.820	1.280e-02	0.239	-2.904	FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	19	-5781636	BC040472	2528	19p13.3	Hs.631846 Hs.705615	19	Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
221900_at	-0.255	3.522	-2.819	1.282e-02	0.239	-2.905	COL8A2	collagen, type VIII, alpha 2	1	-36333432	AI806793	1296	1p34.2	Hs.353001	19	extracellular matrix structural constituent extracellular region basement membrane cell-cell adhesion extracellular matrix organization protein binding, bridging
209220_at	0.633	4.200	2.819	1.282e-02	0.239	-2.905	GPC3	glypican 3	X	-132497441	L47125	2719	Xq26.1	Hs.644108	53	extracellular region proteinaceous extracellular matrix extracellular space plasma membrane integral to plasma membrane anatomical structure morphogenesis anchored to membrane heparan sulfate proteoglycan binding
200983_x_at	-0.345	10.055	-2.819	1.282e-02	0.239	-2.906	CD59	CD59 molecule, complement regulatory protein	11	-33681131, -33681131, -33681131	BF983379	966	11p13	Hs.278573 Hs.709466 Hs.710641	107	protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane	Complement and coagulation cascades Hematopoietic cell lineage
205503_at	-0.339	3.973	-2.819	1.282e-02	0.239	-2.906	PTPN14	protein tyrosine phosphatase, non-receptor type 14	1	-212597633	NM_005401	5784	1q32.2	Hs.696573	13	protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity
202302_s_at	-0.653	9.282	-2.819	1.283e-02	0.239	-2.906	RSRC2	arginine/serine-rich coiled-coil 2	12	-121555225, -121555225	NM_023012	65117	12q24.31	Hs.432996	4
235272_at	0.355	4.572	2.818	1.283e-02	0.239	-2.907	SBSN	suprabasin	19	-40706110	AI814274	374897	19q13.13	Hs.433484	5	extracellular region cytoplasm
200976_s_at	-0.429	9.179	-2.818	1.284e-02	0.239	-2.907	TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	7	27746262	NM_006024	8887	7p15	Hs.34576	21	intracellular apoptosis anti-apoptosis zinc ion binding identical protein binding
222599_s_at	0.326	5.691	2.817	1.287e-02	0.240	-2.909	NAV2	neuron navigator 2	11	19328846, 19691456, 20001211	AU137607	89797	11p15.1	Hs.502116 Hs.551898 Hs.639427 Hs.639428	18	nucleotide binding helicase activity ATP binding nucleus nucleolus cytoplasm hydrolase activity
206168_at	0.226	4.861	2.816	1.289e-02	0.240	-2.910	ZC3H7B	zinc finger CCCH-type containing 7B	22	40027512	NM_025013	23264	22q13.2	Hs.592188	12	nucleic acid binding protein binding intracellular nucleus zinc ion binding interspecies interaction between organisms metal ion binding
244178_at	0.287	4.706	2.816	1.289e-02	0.240	-2.911	COMMD7	COMM domain containing 7	20	-30754153	AW451792	149951	20q11.21	Hs.408427	6	protein binding cellular_component negative regulation of transcription negative regulation of NF-kappaB transcription factor activity tumor necrosis factor-mediated signaling pathway NF-kappaB binding
224879_at	0.619	10.010	2.816	1.289e-02	0.240	-2.911	C9orf123	chromosome 9 open reading frame 123	9	-7786490	BF315994	90871	9p24.1	Hs.7517	4	membrane integral to membrane
91703_at	-0.413	7.837	-2.816	1.290e-02	0.240	-2.911	EHBP1L1	EH domain binding protein 1-like 1	11	65100084	AA149545	254102	11q13.1	Hs.502867	4
211563_s_at	-0.925	6.715	-2.815	1.291e-02	0.240	-2.912	C19orf2	chromosome 19 open reading frame 2	19	35125264	AB006572	8725	19q12	Hs.466391	11	transcription corepressor activity nucleus DNA-directed RNA polymerase II, core complex cytoplasm regulation of transcription from RNA polymerase II promoter protein folding response to virus prefoldin complex unfolded protein binding
209155_s_at	-0.541	9.084	-2.815	1.292e-02	0.240	-2.913	NT5C2	5'-nucleotidase, cytosolic II	10	-104835929	BC001595	22978	10q24.32-q24.33	Hs.97439	12	nucleotide binding magnesium ion binding protein binding cytoplasm cytosol 5'-nucleotidase activity 5'-nucleotidase activity nucleotide metabolic process hydrolase activity	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
217854_s_at	-0.456	8.703	-2.815	1.292e-02	0.240	-2.913	POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	19	-1037577	NM_002695	5434	19p13.3	Hs.24301	91	nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter interspecies interaction between organisms	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
204879_at	-0.429	5.889	-2.815	1.292e-02	0.240	-2.913	PDPN	podoplanin	1	13782838, 13784553	NM_006474	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
203730_s_at	-0.513	4.232	-2.814	1.296e-02	0.240	-2.915	ZKSCAN5	zinc finger with KRAB and SCAN domains 5	7	98940208, 98940508	BF196931	23660	7q22	Hs.110839	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
232696_at	0.480	3.719	2.813	1.297e-02	0.241	-2.916	LOC648556	uncharacterized gastric protein ZA43P	16		AI394334	648556		Hs.203594
225001_at	0.303	6.224	2.813	1.298e-02	0.241	-2.917	RAB3D	RAB3D, member RAS oncogene family	19	-11296092	AI744658	9545	19p13.2	Hs.655274	13	nucleotide binding GTPase activity protein binding GTP binding plasma membrane exocytosis small GTPase mediated signal transduction protein transport
209476_at	-0.522	7.045	-2.812	1.299e-02	0.241	-2.918	TMX1	thioredoxin-related transmembrane protein 1	14	50776635	AL080080	81542	14q22.1	Hs.125221	10	membrane fraction nucleus endoplasmic reticulum endoplasmic reticulum membrane DNA replication transport ER to Golgi vesicle-mediated transport anti-apoptosis response to stress signal transduction cell proliferation disulfide oxidoreductase activity membrane integral to membrane electron transport chain arsenate reductase (thioredoxin) activity leukocyte activation cell redox homeostasis positive regulation of transcription, DNA-dependent positive regulation of growth
221641_s_at	-0.499	7.343	-2.812	1.301e-02	0.241	-2.919	ACOT9	acyl-CoA thioesterase 9	X	-23631697	AF241787	23597	Xp22.11	Hs.298885	6	acetyl-CoA hydrolase activity carboxylesterase activity mitochondrion acyl-CoA metabolic process hydrolase activity
229985_at	0.715	7.367	2.812	1.301e-02	0.241	-2.919	BTNL9	butyrophilin-like 9	5	180399830	AI912653	153579	5q35.3	Hs.546502	4	membrane integral to membrane
221020_s_at	-0.424	6.232	-2.812	1.301e-02	0.241	-2.919	SLC25A32	solute carrier family 25, member 32	8	-104480042	NM_030780	81034	8q22.3	Hs.607819	6	transporter activity binding mitochondrion mitochondrial inner membrane transport folic acid transporter activity folic acid transport membrane integral to membrane
1552732_at	-1.263	10.048	-2.812	1.301e-02	0.241	-2.919	ABRA	actin-binding Rho activating protein	8	-107840886	AL832152	137735	8q23.1	Hs.374668	12	protein import into nucleus, translocation transcription coactivator activity actin binding cytoplasm plasma membrane protein transport actin cytoskeleton sarcomere positive regulation of Rho protein signal transduction positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription factor activity intracellular protein transmembrane transport
225885_at	-0.618	8.605	-2.811	1.302e-02	0.241	-2.920	EEA1	early endosome antigen 1	12	-91690415	AI336848	8411	12q22	Hs.567367	32	calmodulin binding phosphatidylinositol binding intracellular membrane fraction cytoplasm early endosome cytosol serine-pyruvate aminotransferase complex vesicle fusion zinc ion binding membrane synaptic vesicle to endosome fusion extrinsic to plasma membrane GTP-dependent protein binding protein homodimerization activity early endosome to late endosome transport metal ion binding	Endocytosis
221311_x_at	-0.398	7.824	-2.811	1.302e-02	0.241	-2.920	LYRM2	LYR motif containing 2	6	-90398663	NM_020466	57226	6q14.2-q16.1	Hs.177275	5
226651_at	-0.859	7.921	-2.811	1.303e-02	0.241	-2.920	HOMER1	homer homolog 1 (Drosophila)	5	-78705541	AW052119	9456	5q14.2	Hs.591761	33	skeletal muscle contraction protein binding membrane fraction cytoplasm plasma membrane integral to plasma membrane activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway synaptic transmission postsynaptic density Z disc cell junction positive regulation of calcium ion transport via store-operated calcium channel activity costamere synapse postsynaptic membrane skeletal muscle fiber development
200775_s_at	-0.333	10.099	-2.811	1.303e-02	0.241	-2.921	HNRNPK	heterogeneous nuclear ribonucleoprotein K	9	-85772817, -85772817	BC000355	3190	9q21.32-q21.33	Hs.522257	89	nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm signal transduction RNA splicing heterogeneous nuclear ribonucleoprotein complex interspecies interaction between organisms
243109_at	0.290	3.106	2.811	1.304e-02	0.241	-2.921	MCTP2	multiple C2 domains, transmembrane 2	15	92642433, 92700167	AA748418	55784	15q26.2	Hs.33368 Hs.592017	7	calcium ion binding calcium-dependent phospholipid binding membrane fraction membrane integral to membrane calcium-mediated signaling
1552626_a_at	0.458	4.315	2.810	1.304e-02	0.241	-2.921	TMEM163	transmembrane protein 163	2	-134929800	NM_030923	81615	2q21.3	Hs.369471 Hs.595089	5	membrane integral to membrane
217735_s_at	-0.434	4.990	-2.810	1.304e-02	0.241	-2.921	EIF2AK1	eukaryotic translation initiation factor 2-alpha kinase 1	7	-6028405	AW007368	27102	7p22	Hs.719136	19	nucleotide binding eukaryotic translation initiation factor 2alpha kinase activity ATP binding cytoplasm response to stress negative regulation of cell proliferation response to external stimulus transferase activity negative regulation of translation heme binding protein homodimerization activity negative regulation of translational initiation by iron protein amino acid autophosphorylation negative regulation of hemoglobin biosynthetic process
232722_at	0.265	3.025	2.810	1.304e-02	0.241	-2.921	RNASET2	ribonuclease T2	6	-167262993	AK001769	8635	6q27	Hs.529989	11	RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity
224819_at	0.443	6.667	2.810	1.305e-02	0.241	-2.921	TCEAL8	transcription elongation factor A (SII)-like 8	X	-102394578	AI743979	90843	Xq22.1	Hs.389734	4	nucleus regulation of transcription
214273_x_at	0.287	6.788	2.810	1.306e-02	0.241	-2.922	C16orf35	chromosome 16 open reading frame 35	16	-75803, -75803	AV704353	8131	16p13.3	Hs.19699	6	molecular_function cellular_component biological_process
1560097_at	0.345	4.776	2.810	1.306e-02	0.241	-2.923	FHAD1	forkhead-associated (FHA) phosphopeptide binding domain 1	1	15446354	AB067524	114827	1p36.21	Hs.659997	6
213313_at	-0.541	8.556	-2.808	1.310e-02	0.241	-2.925	RABGAP1	RAB GTPase activating protein 1	9	124743108	AI922519	23637	9q33.2-q33.3	Hs.271341	6	GTPase activator activity Rab GTPase activator activity intracellular cytoplasm centrosome cytosol microtubule associated complex cell cycle tubulin binding regulation of Rab GTPase activity
222442_s_at	-0.469	7.601	-2.808	1.310e-02	0.241	-2.925	ARL8B	ADP-ribosylation factor-like 8B	3	5138929	AW055237	55207	3p26.1	Hs.250009 Hs.719100	10	nucleotide binding GTPase activity GTP binding intracellular cytoplasm lysosomal membrane endosome chromosome segregation small GTPase mediated signal transduction membrane GDP binding midbody late endosome membrane alpha-tubulin binding beta-tubulin binding spindle midzone
208860_s_at	-0.533	7.456	-2.808	1.311e-02	0.241	-2.926	ATRX	alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)	X	-76647011	U09820	546	Xq13.1-q21.1	Hs.533526 Hs.645562 Hs.653797	66	nucleotide binding DNA binding DNA helicase activity protein binding ATP binding nucleus nuclear heterochromatin DNA repair DNA methylation DNA recombination regulation of transcription, DNA-dependent response to DNA damage stimulus zinc ion binding hydrolase activity metal ion binding
224744_at	-0.818	5.412	-2.808	1.312e-02	0.241	-2.926	IMPAD1	inositol monophosphatase domain containing 1	8	-58033041	AW628838	54928	8q12.1	Hs.716471	4	magnesium ion binding inositol-1(or 4)-monophosphatase activity membrane integral to membrane hydrolase activity
219256_s_at	0.424	4.260	2.808	1.312e-02	0.241	-2.926	SH3TC1	SH3 domain and tetratricopeptide repeats 1	4	8251959	NM_018986	54436	4p16.1	Hs.479116	5	binding cellular_component biological_process
242422_at	-0.551	4.508	-2.808	1.312e-02	0.241	-2.927	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	AA180161	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
230977_at	0.262	6.985	2.807	1.312e-02	0.241	-2.927	NPM2	nucleophosmin/nucleoplasmin 2	8	21938299	AI016313	10361	8p21.3	Hs.131055	5	cytoplasmic chromatin nuclear chromatin nucleic acid binding nucleus chromatin remodeling regulation of exit from mitosis single fertilization embryonic development oocyte differentiation histone binding positive regulation of meiosis
236302_at	2.416	3.500	2.807	1.313e-02	0.241	-2.927	PPM1E	protein phosphatase 1E (PP2C domain containing)	17	54188230	R40892	22843	17q22	Hs.245044	5	magnesium ion binding protein serine/threonine phosphatase activity nucleus nucleolus cytoplasm protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity manganese ion binding
212870_at	-0.748	9.163	-2.807	1.314e-02	0.241	-2.928	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	AI628605	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
209480_at	1.290	4.013	2.807	1.314e-02	0.241	-2.928	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M16276	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
210249_s_at	-0.326	7.532	-2.805	1.318e-02	0.242	-2.931	NCOA1	nuclear receptor coactivator 1	2	24660849	U59302	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
225659_at	-0.507	5.094	-2.804	1.321e-02	0.242	-2.933	SPOPL	speckle-type POZ protein-like	2	138975819	BF516590	339745	2q22.1	Hs.333297	6	protein binding nucleus modification-dependent protein catabolic process
224392_s_at	0.438	4.446	2.804	1.321e-02	0.242	-2.933	OPN3	opsin 3	1	-239823074	AF303588	23596	1q43	Hs.409081 Hs.719236	10	integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway visual perception phototransduction G-protein coupled photoreceptor activity membrane protein-chromophore linkage regulation of circadian rhythm response to stimulus
236294_at	-0.314	5.729	-2.804	1.322e-02	0.242	-2.934	HUWE1	HECT, UBA and WWE domain containing 1	X	-53575796	R37670	10075	Xp11.22	Hs.136905	28	protein polyubiquitination DNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm protein modification process histone ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation	Ubiquitin mediated proteolysis
239004_at	0.240	5.936	2.803	1.323e-02	0.242	-2.934	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	AI041019	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
1570627_at	0.328	4.230	2.803	1.323e-02	0.242	-2.934	TCEB3	transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)	1	23942442	BC019949	6924	1p36.1	Hs.15535	26	DNA binding protein binding nucleus nucleoplasm cytoplasm regulation of transcription from RNA polymerase II promoter integral to membrane transcription regulator activity regulation of transcription
202518_at	-0.415	7.330	-2.803	1.323e-02	0.242	-2.934	BCL7B	B-cell CLL/lymphoma 7B	7	-72588621	NM_001707	9275	7q11.23	Hs.647051	8	actin binding cellular_component biological_process
217827_s_at	-0.762	8.679	-2.803	1.324e-02	0.242	-2.935	SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	15	-63042415, -63042415	NM_016630	51324	15q21-q22	Hs.242458	10	cytoplasm endosome Golgi apparatus cytosol cytosol cell death membrane trans-Golgi network transport vesicle trans-Golgi network transport vesicle CD4 receptor binding CD4 receptor binding antigen receptor-mediated signaling pathway
218659_at	-0.436	6.876	-2.803	1.325e-02	0.242	-2.935	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	NM_018263	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
206052_s_at	-0.525	6.785	-2.803	1.325e-02	0.242	-2.935	SLBP	stem-loop binding protein	4	-1664324	NM_006527	7884	4p16.3	Hs.298345	27	mRNA binding nucleus nucleoplasm cytoplasm mRNA processing histone mRNA 3'-end processing ribonucleoprotein complex
212231_at	-0.444	7.872	-2.802	1.326e-02	0.242	-2.936	FBXO21	F-box protein 21	12	-116065967	AB020682	23014	12q24.22	Hs.719089	7	ubiquitin ligase complex ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process
212441_at	-0.438	9.842	-2.802	1.327e-02	0.242	-2.937	KIAA0232	KIAA0232	4	6835359	D86985	9778	4p16.1	Hs.79276	7	nucleotide binding ATP binding
215418_at	0.358	5.060	2.802	1.327e-02	0.242	-2.937	PARVA	parvin, alpha	11	12355721	AK022316	55742	11p15.3	Hs.607144	17	actin binding protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion lamellipodium cell junction	Focal adhesion
225240_s_at	-0.546	7.880	-2.802	1.327e-02	0.242	-2.937	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BE220026	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
200719_at	-0.555	8.289	-2.802	1.328e-02	0.242	-2.937	SKP1	S-phase kinase-associated protein 1	5	-133519980	BE964043	6500	5q31	Hs.171626 Hs.710433	63	protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
1569792_a_at	-0.328	5.239	-2.801	1.328e-02	0.242	-2.938	C12orf72	chromosome 12 open reading frame 72	12	31691360, 31703387, 31703875	BC039107	254013	12p11.21	Hs.585084	2
224068_x_at	-0.503	6.791	-2.801	1.328e-02	0.242	-2.938	RBM22	RNA binding motif protein 22	5	-150050544	U39402	55696	5q33.1	Hs.713564	17	protein import into nucleus, translocation nucleotide binding RNA binding nucleus spliceosomal complex nucleolus cytoplasm mRNA processing zinc ion binding RNA splicing metal ion binding calcium-dependent protein binding
205687_at	-0.482	7.337	-2.801	1.329e-02	0.242	-2.938	UBFD1	ubiquitin family domain containing 1	16	23476362	NM_019116	56061	16p12	Hs.3459	3
216898_s_at	-0.877	4.865	-2.801	1.329e-02	0.242	-2.938	COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	2	227737524	U02520	1285	2q36-q37	Hs.570065	77	integrin binding integrin binding extracellular matrix structural constituent protein binding extracellular region collagen collagen type IV induction of apoptosis activation of caspase activity cell adhesion cell surface receptor linked signal transduction sensory perception of sound blood circulation metalloendopeptidase inhibitor activity negative regulation of cell proliferation negative regulation of angiogenesis
229730_at	-0.747	9.352	-2.801	1.330e-02	0.242	-2.939	SMTNL2	smoothelin-like 2	17	4434024, 4434582	AI193973	342527	17p13.2	Hs.441709	2
203661_s_at	-0.453	8.860	-2.799	1.334e-02	0.243	-2.941	TMOD1	tropomodulin 1	9	99326257	BC002660	7111	9q22.3	Hs.494595	18	actin binding tropomyosin binding nucleus cytoplasm membrane myofibril myofibril assembly cortical cytoskeleton
225519_at	-0.489	7.838	-2.799	1.334e-02	0.243	-2.942	PPP4R2	protein phosphatase 4, regulatory subunit 2	3	73128808	AA206408	151987	3p13	Hs.431092	7	protein binding centrosome mRNA processing protein modification process RNA splicing
223460_at	0.300	6.687	2.799	1.336e-02	0.243	-2.943	CAMKK1	calcium/calmodulin-dependent protein kinase kinase 1, alpha	17	-3715199, -3710365, -3710365	AL136576	84254	17p13.2	Hs.8417	16	nucleotide binding calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity	Adipocytokine signaling pathway
220459_at	0.457	3.644	2.798	1.336e-02	0.243	-2.943	MCM3APAS	MCM3AP antisense RNA (non-protein coding)	21	46473585	NM_018118	114044	21q22.3	Hs.709346	3
236523_at	-0.731	10.116	-2.798	1.337e-02	0.243	-2.944	LOC285556	hypothetical protein LOC285556	4		BF435831	285556	4q23	Hs.480371
217596_at	-0.295	5.341	-2.798	1.338e-02	0.243	-2.944	UPF3A	UPF3 regulator of nonsense transcripts homolog A (yeast)	13	114065179	AA649851	65110	13q34	Hs.533855	20	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay RNA binding nucleocytoplasmic transporter activity protein binding nucleus cytoplasm transport mRNA transport
202223_at	-0.403	6.452	-2.798	1.338e-02	0.243	-2.944	STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	11	124967948	NM_002219	3703	11q23.3	Hs.504237	9	dolichyl-diphosphooligosaccharide-protein glycotransferase activity membrane fraction endoplasmic reticulum protein amino acid glycosylation oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine
227945_at	-0.887	7.217	-2.798	1.338e-02	0.243	-2.945	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	BE882538	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
212990_at	-0.500	5.635	-2.797	1.340e-02	0.243	-2.946	SYNJ1	synaptojanin 1	21	-32922939, -32922939	AB020717	8867	21q22.2	Hs.473632	31	RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity cytoplasm dephosphorylation hydrolase activity synaptic vesicle endocytosis	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
235301_at	0.523	5.912	2.797	1.340e-02	0.243	-2.946	KIAA1324L	KIAA1324-like	7	-86347173, -86347173	AI797353	222223	7q21.12	Hs.208093	3	G-protein coupled receptor activity protein binding G-protein coupled receptor protein signaling pathway membrane integral to membrane
201830_s_at	-0.708	6.960	-2.796	1.342e-02	0.243	-2.947	NET1	neuroepithelial cell transforming 1	10	5444517, 5478545	NM_005863	10276	10p15	Hs.25155	19	regulation of cell growth guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity cellular_component intracellular nucleus cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction
1556665_at	0.251	4.054	2.796	1.342e-02	0.243	-2.947	TTC6	tetratricopeptide repeat domain 6	14		BU680030	115669	14q21.1	Hs.670915	2	binding
209342_s_at	-0.805	6.352	-2.796	1.343e-02	0.243	-2.948	IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	8	42247985	AF080158	3551	8p11.2	Hs.597664	172	nucleotide binding B cell homeostasis ATP binding cytoplasm cytosol protein amino acid phosphorylation IkappaB kinase activity transcription activator activity transferase activity identical protein binding positive regulation of NF-kappaB transcription factor activity	MAPK signaling pathway Chemokine signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Pancreatic cancer Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer
225429_at	-0.775	8.456	-2.796	1.344e-02	0.243	-2.948	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	BF437011	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
207079_s_at	-0.599	7.534	-2.796	1.344e-02	0.243	-2.948	MED6	mediator complex subunit 6	14	-70120709	NM_005466	10001	14q24.2	Hs.497353	22	RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter
1561518_at	0.288	5.110	2.795	1.344e-02	0.243	-2.949	LOC283914	hypothetical protein LOC283914	16	34455287, 34455402	BC038774	283914	16p11.2-p11.1	Hs.385772	1
203313_s_at	-0.563	4.866	-2.795	1.345e-02	0.243	-2.949	TGIF1	TGFB-induced factor homeobox 1	18	3402071, 3437607, 3439972, 3440030, 3440171, 3441590, 3443771	NM_003244	7050	18p11.3	Hs.373550	38	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription corepressor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding
201123_s_at	-0.915	9.932	-2.795	1.345e-02	0.243	-2.949	EIF5A	eukaryotic translation initiation factor 5A	17	7151041, 7151579, 7152011, 7152417	NM_001970	1984	17p13-p12	Hs.534314	52	RNA binding translation initiation factor activity translation elongation factor activity nucleus annulate lamellae nuclear pore cytoplasm endoplasmic reticulum cytosol mRNA export from nucleus translation translational frameshifting protein export from nucleus nucleocytoplasmic transport nucleocytoplasmic transport induction of apoptosis cell proliferation peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine protein transport membrane U6 snRNA binding viral genome replication ribosome binding positive regulation of translational elongation positive regulation of translational termination positive regulation of translational initiation protein N-terminus binding intracellular protein transmembrane transport
223018_at	-0.271	6.731	-2.795	1.345e-02	0.243	-2.949	NOB1	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)	16	-68333274	BC000050	28987	16q22.3	Hs.271695 Hs.606475	8	protein binding nucleus zinc ion binding metal ion binding
222430_s_at	-0.440	7.568	-2.795	1.346e-02	0.243	-2.950	YTHDF2	YTH domain family, member 2	1	28935722	BC002559	51441	1p35	Hs.532286	5	humoral immune response
217770_at	-0.460	7.001	-2.795	1.347e-02	0.243	-2.950	PIGT	phosphatidylinositol glycan anchor biosynthesis, class T	20	43478137	NM_015937	51604	20q12-q13.12	Hs.437388	19	GPI-anchor transamidase activity protein binding endoplasmic reticulum membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein GPI-anchor transamidase complex	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
230821_at	-0.429	5.839	-2.794	1.348e-02	0.243	-2.951	ZNF148	zinc finger protein 148	3	-126427202	AW594167	7707	3q21	Hs.592591	34	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex nucleolus Golgi apparatus cellular defense response gamete generation zinc ion binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
204260_at	-2.349	4.431	-2.794	1.349e-02	0.243	-2.952	CHGB	chromogranin B (secretogranin 1)	20	5839973	NM_001819	1114	20pter-p12	Hs.516874	35	hormone activity protein binding extracellular region
217489_s_at	0.236	2.368	2.793	1.352e-02	0.244	-2.954	IL6R	interleukin 6 receptor	1	152644292	S72848	3570	1q21	Hs.709210	132	hepatic immune response monocyte chemotaxis positive regulation of leukocyte chemotaxis receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity receptor binding extracellular region plasma membrane interleukin-6 receptor complex acute-phase response integral to membrane apical plasma membrane enzyme binding endocrine pancreas development endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production response to cytokine stimulus positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity regulation of apoptosis positive regulation of osteoblast differentiation positive regulation of anti-apoptosis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium interleukin-6-mediated signaling pathway ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
236050_at	0.307	5.484	2.792	1.354e-02	0.244	-2.955	C11orf35	chromosome 11 open reading frame 35	11	-544856	AI656897	256329	11p15.5	Hs.669395	2
212224_at	-1.323	7.934	-2.791	1.357e-02	0.244	-2.957	ALDH1A1	aldehyde dehydrogenase 1 family, member A1	9	-74705406	NM_000689	216	9q21.13	Hs.76392	51	retinal dehydrogenase activity aldehyde dehydrogenase (NAD) activity aldehyde dehydrogenase (NAD) activity Ras GTPase activator activity androgen binding cytoplasm cytosol cellular aldehyde metabolic process oxidoreductase activity oxidation reduction	Retinol metabolism Metabolic pathways
225264_at	-0.338	7.534	-2.791	1.357e-02	0.244	-2.957	RARS2	arginyl-tRNA synthetase 2, mitochondrial	6	-88280815	AK023550	57038	6q16.1	Hs.485910	8	nucleotide binding arginine-tRNA ligase activity protein binding ATP binding cytoplasm mitochondrion mitochondrial matrix arginyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
224444_s_at	0.590	5.346	2.791	1.357e-02	0.244	-2.957	C1orf97	chromosome 1 open reading frame 97	1	209622719	BC005997	84791	1q32.3	Hs.523932	4
230893_at	-0.877	6.116	-2.791	1.358e-02	0.244	-2.958	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	5	34965454	AI223870	134218	5p13.2	Hs.131887	5	nucleic acid binding intracellular zinc ion binding heat shock protein binding metal ion binding
200738_s_at	-0.635	11.446	-2.791	1.358e-02	0.244	-2.958	PGK1	phosphoglycerate kinase 1	X	77246321	NM_000291	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
219918_s_at	-0.366	3.070	-2.790	1.358e-02	0.244	-2.958	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	1	-195319879	NM_018123	259266	1q31	Hs.121028	35	calmodulin binding nucleus cytoplasm cell cycle mitosis cell division
228794_at	-0.923	12.513	-2.790	1.360e-02	0.244	-2.959	XIRP2	xin actin-binding repeat containing 2	2	167468220	AA211780	129446	2q24.3	Hs.73680	8	actin binding actin cytoskeleton organization cell junction
205758_at	0.379	4.613	2.790	1.360e-02	0.244	-2.959	CD8A	CD8a molecule	2	-86865239, -86865239	AW006735	925	2p12	Hs.85258	72	protein binding extracellular region plasma membrane integral to plasma membrane immune response transmembrane receptor protein tyrosine kinase signaling pathway coreceptor activity antigen processing and presentation T cell receptor complex T cell activation MHC class I protein binding	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage T cell receptor signaling pathway Primary immunodeficiency
205008_s_at	0.773	6.424	2.790	1.360e-02	0.244	-2.959	CIB2	calcium and integrin binding family member 2	15	-76184045	NM_006383	10518	15q24	Hs.129867	6	calcium ion binding protein binding
225164_s_at	-0.348	5.534	-2.790	1.360e-02	0.244	-2.959	EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	15	38013638	AB037759	440275	15q15.1	Hs.656673	10	nucleotide binding eukaryotic translation initiation factor 2alpha kinase activity aminoacyl-tRNA ligase activity protein binding ATP binding intracellular cytoplasm tRNA aminoacylation for protein translation regulation of translational initiation protein amino acid phosphorylation transferase activity cytosolic ribosome
233977_at	0.423	5.994	2.790	1.360e-02	0.244	-2.959	KIAA1772	KIAA1772	18	17076200	AB051559	80000	18q11.1-q11.2	Hs.149020	4	membrane integral to membrane
236726_at	0.334	3.702	2.790	1.361e-02	0.244	-2.959	RGS6	regulator of G-protein signaling 6	14	71469538	H41121	9628	14q24.3	Hs.509872	13	signal transducer activity GTPase activator activity cellular_component cytoplasm heterotrimeric G-protein complex intracellular signaling cascade regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction membrane
1553515_at	0.314	4.582	2.789	1.362e-02	0.244	-2.960	MYEOV2	myeloma overexpressed 2	2	-240718914, -240714652	NM_138336	150678	2q37.3	Hs.293884	2
234684_s_at	0.289	2.616	2.789	1.362e-02	0.244	-2.960	KRTAP4-4	keratin associated protein 4-4	17	-36569431	AJ296168	84616	17q12-q21	Hs.307022	2	keratin filament
203813_s_at	0.436	4.187	2.789	1.363e-02	0.244	-2.961	SLIT3	slit homolog 3 (Drosophila)	5	-168025648	NM_003062	6586	5q35	Hs.604116	17	structural molecule activity calcium ion binding protein binding extracellular region extracellular space multicellular organismal development axon guidance central nervous system development organ morphogenesis cell differentiation	Axon guidance
218300_at	0.319	7.164	2.789	1.363e-02	0.244	-2.961	C16orf53	chromosome 16 open reading frame 53	16	29735028	NM_024516	79447	16p11.2	Hs.702841	7
224621_at	-0.344	8.366	-2.788	1.366e-02	0.245	-2.963	MAPK1	mitogen-activated protein kinase 1	22	-20453318, -20443946	AA129773	5594	22q11.2 22q11.21	Hs.431850	822	MAPKKK cascade nucleotide binding phosphotyrosine binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol cytoskeleton protein amino acid phosphorylation induction of apoptosis chemotaxis response to DNA damage stimulus cell cycle Ras protein signal transduction synaptic transmission organ morphogenesis transferase activity MAP kinase 2 activity cytosine metabolic process lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to exogenous dsRNA interspecies interaction between organisms negative regulation of cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation TGF-beta signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Type II diabetes mellitus Alzheimer's disease Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
225851_at	-0.365	7.347	-2.788	1.366e-02	0.245	-2.963	FNTB	farnesyltransferase, CAAX box, beta	14	64523259	BF131248	2342	14q23-q24	Hs.632345	26	farnesyltranstransferase activity protein farnesyltransferase activity protein binding zinc ion binding negative regulation of cell proliferation transferase activity protein amino acid farnesylation wound healing metal ion binding positive regulation of fibroblast proliferation
218145_at	1.465	5.963	2.787	1.366e-02	0.245	-2.963	TRIB3	tribbles homolog 3 (Drosophila)	20	309307	NM_021158	57761	20p13-p12.2	Hs.516826	36	transcription corepressor activity protein kinase activity protein kinase inhibitor activity protein binding protein binding ATP binding nucleus nucleolus protein amino acid phosphorylation negative regulation of protein kinase activity apoptosis response to stress protein kinase binding protein kinase binding regulation of MAP kinase activity regulation of transcription
215121_x_at	0.747	5.938	2.787	1.367e-02	0.245	-2.963	IGL@	immunoglobulin lambda locus	22		AA680302	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
41858_at	0.346	6.059	2.787	1.368e-02	0.245	-2.964	PGAP2	post-GPI attachment to proteins 2	11	3775529, 3775624, 3775707, 3775765, 3785815, 3786341	AL049261	27315	11p15.5	Hs.133968	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus GPI anchor biosynthetic process protein transporter activity membrane integral to membrane
206633_at	-2.206	7.373	-2.787	1.369e-02	0.245	-2.965	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)	2	-175320568	NM_000079	1134	2q24-q32	Hs.434479	43	skeletal muscle contraction nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport signal transduction neuromuscular synaptic transmission neuromuscular junction development cell surface acetylcholine receptor activity integral to membrane regulation of action potential in neuron cell junction neuromuscular junction regulation of membrane potential postsynaptic membrane muscle maintenance skeletal muscle tissue growth neuromuscular process neuron maintenance
1553148_a_at	-0.698	5.267	-2.786	1.369e-02	0.245	-2.965	SNX13	sorting nexin 13	7	-17796910	R75838	23161	7p21.1	Hs.487648	10	signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding
209199_s_at	-0.512	11.643	-2.786	1.370e-02	0.245	-2.965	MEF2C	myocyte enhancer factor 2C	5	-88049814, -88049814	N22468	4208	5q14	Hs.653394	56	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development negative regulation of specific transcription from RNA polymerase II promoter nuclear speck cell differentiation sequence-specific DNA binding positive regulation of survival gene product expression	MAPK signaling pathway
214736_s_at	-0.412	7.879	-2.786	1.370e-02	0.245	-2.965	ADD1	adducin 1 (alpha)	4	2815381	BE898639	118	4p16.3	Hs.183706 Hs.701490	139	calmodulin binding nucleus cytoplasm cytosol cytoskeleton plasma membrane transcription factor binding F-actin capping protein complex actin cytoskeleton organization spectrin binding positive regulation of protein binding protein homodimerization activity metal ion binding protein heterodimerization activity actin filament binding barbed-end actin filament capping actin filament bundle formation
231251_at	0.416	3.737	2.786	1.370e-02	0.245	-2.966	WIPF2	WAS/WASL interacting protein family, member 2	17	35629099	AW295547	147179	17q21.1-q21.2	Hs.421622 Hs.705989	11	actin binding cytoplasm cytoskeleton
215111_s_at	-0.394	10.524	-2.786	1.371e-02	0.245	-2.966	TSC22D1	TSC22 domain family, member 1	13	-43905658, -43905654	AK027071	8848	13q14	Hs.507916	23	transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter
208070_s_at	-0.381	7.680	-2.785	1.372e-02	0.245	-2.967	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	6	-111726926	NM_002912	5980	6q21	Hs.232021	19	nucleotide binding DNA binding DNA-directed DNA polymerase activity nucleus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process DNA-dependent DNA replication DNA repair response to DNA damage stimulus zinc ion binding transferase activity nucleotidyltransferase activity metal ion binding	Metabolic pathways
225056_at	0.801	6.453	2.785	1.372e-02	0.245	-2.967	SIPA1L2	signal-induced proliferation-associated 1 like 2	1	-230600334	AB037810	57568	1q42.2	Hs.715656	8	GTPase activator activity protein binding intracellular regulation of small GTPase mediated signal transduction
229578_at	-0.560	9.090	-2.785	1.374e-02	0.245	-2.969	JPH2	junctophilin 2	20	-42238870, -42173750	AA716165	57158	20q13.12	Hs.441737	11	protein binding membrane fraction microsome plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
214955_at	0.349	6.566	2.784	1.376e-02	0.245	-2.969	TMPRSS6	transmembrane protease, serine 6	22	-35791424	AI912086	164656	22q12.3	Hs.370885	16	angiogenesis serine-type endopeptidase activity plasma membrane proteolysis intracellular signaling cascade peptidase activity integral to membrane extracellular matrix organization fibrinolysis
201796_s_at	0.251	6.795	2.783	1.378e-02	0.245	-2.971	VARS	valyl-tRNA synthetase	6	-31853275, -3191374, -3006978	BE790854	7407	6p21.3	Hs.520026	15	nucleotide binding valine-tRNA ligase activity protein binding ATP binding intracellular cytoplasm mitochondrion cytosol translational elongation valyl-tRNA aminoacylation defense response response to unfolded protein response to nutrient ligase activity protein complex NF-kappaB binding	Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis
230852_at	-0.554	8.114	-2.783	1.378e-02	0.245	-2.971	STAC3	SH3 and cysteine rich domain 3	12	-55923508	AW663959	246329	12q13.3	Hs.417595	4	intracellular signaling cascade zinc ion binding diacylglycerol binding identical protein binding metal ion binding
229623_at	0.349	6.597	2.782	1.380e-02	0.246	-2.972	FLJ12993	hypothetical LOC441027	4	-83624627	BF508344	441027	4q21.22	Hs.507676	1
212206_s_at	-0.651	7.769	-2.782	1.381e-02	0.246	-2.973	H2AFV	H2A histone family, member V	7	-44839737, -44833012	BF343852	94239	7p13	Hs.488189	12	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
233208_x_at	-0.547	4.887	-2.782	1.383e-02	0.246	-2.974	CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	14	91658081	AA583986	53981	14q31.1	Hs.657632	24	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus hydrolase activity
206121_at	-1.015	10.853	-2.781	1.383e-02	0.246	-2.974	AMPD1	adenosine monophosphate deaminase 1 (isoform M)	1	-115017244	NM_000036	270	1p13	Hs.89570	59	AMP deaminase activity purine base metabolic process nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process hydrolase activity	Purine metabolism Biosynthesis of plant hormones Metabolic pathways
222859_s_at	0.558	4.120	2.781	1.384e-02	0.246	-2.975	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	AA150186	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
232591_s_at	-0.374	3.859	-2.781	1.385e-02	0.246	-2.975	TMEM30A	transmembrane protein 30A	6	-76019357	AK022883	55754	6q14.1	Hs.108530	7	membrane integral to membrane
222642_s_at	-0.522	5.374	-2.781	1.386e-02	0.246	-2.976	TMEM33	transmembrane protein 33	4	41631893	BC000948	55161	4p13	Hs.31082	5	protein binding biological_process membrane integral to membrane melanosome
35150_at	0.299	7.161	2.780	1.386e-02	0.246	-2.976	CD40	CD40 molecule, TNF receptor superfamily member 5	20	44180312	X60592	958	20q12-q13.2	Hs.472860	290	receptor activity extracellular region plasma membrane plasma membrane integral to plasma membrane protein complex assembly inflammatory response enzyme binding platelet activation B cell proliferation positive regulation of I-kappaB kinase/NF-kappaB cascade	Cytokine-cytokine receptor interaction Cell adhesion molecules (CAMs) Toll-like receptor signaling pathway Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Primary immunodeficiency
202213_s_at	-0.568	5.706	-2.780	1.386e-02	0.246	-2.976	CUL4B	cullin 4B	X	-119542473, -119542473	AI650819	8450	Xq23	Hs.102914	28	molecular_function protein binding cellular_component DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
210299_s_at	-0.545	12.759	-2.780	1.387e-02	0.246	-2.977	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF063002	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
1554705_at	0.336	5.210	2.780	1.387e-02	0.246	-2.977	SCARA5	scavenger receptor class A, member 5 (putative)	8	-27783668	BC033153	286133	8p21.1	Hs.591833	6	receptor activity scavenger receptor activity iron ion binding protein binding plasma membrane integral to plasma membrane ion transport cellular iron ion homeostasis endocytosis cell surface cellular response to heat iron ion transmembrane transport protein homotrimerization ferritin receptor activity
232051_at	0.313	4.399	2.780	1.388e-02	0.246	-2.977	CCDC102A	coiled-coil domain containing 102A	16	-56103592	BC004307	92922	16q21	Hs.644611	2
209026_x_at	-0.783	9.366	-2.780	1.388e-02	0.246	-2.977	TUBB	tubulin, beta	6	30796135, 2136731, 1935034	AF141349	203068	6p21.33	Hs.636480 Hs.706187 Hs.714425	39	nucleotide binding GTPase activity structural constituent of cytoskeleton GTP binding cytoskeleton microtubule cell motion microtubule-based movement flotillin complex natural killer cell mediated cytotoxicity MHC class I protein binding spindle assembly protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
201687_s_at	-0.450	7.295	-2.779	1.390e-02	0.246	-2.979	API5	apoptosis inhibitor 5	11	43290080	NM_006595	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
208642_s_at	-0.402	8.198	-2.779	1.391e-02	0.246	-2.979	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	2	216682264	AA205834	7520	2q35	Hs.388739	148	nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding promoter binding hydrolase activity provirus integration initiation of viral infection	Non-homologous end-joining
225953_at	-0.312	8.944	-2.778	1.393e-02	0.246	-2.981	RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	18	-31823789	AI684281	55197	18q12.2	Hs.464912	3
224454_at	-0.420	2.590	-2.778	1.394e-02	0.246	-2.981	ETNK1	ethanolamine kinase 1	12	22669342, 22669342	BC006111	55500	12p12.1	Hs.29464	4	nucleotide binding ethanolamine kinase activity ATP binding cytoplasm phosphatidylethanolamine biosynthetic process transferase activity	Glycerophospholipid metabolism Metabolic pathways
1555600_s_at	0.236	4.705	2.778	1.394e-02	0.246	-2.981	APOL4	apolipoprotein L, 4	22	-34915121	AF305226	80832	22q11.2-q13.2	Hs.115099	9	molecular_function extracellular region lipid metabolic process lipid transport lipid binding lipoprotein metabolic process
206245_s_at	-0.796	6.814	-2.777	1.395e-02	0.246	-2.982	IVNS1ABP	influenza virus NS1A binding protein	1	-183532144	NM_006469	10625	1q25.1-q31.1	Hs.497183	9	protein binding nucleus nucleoplasm transcription factor complex spliceosomal complex cytoplasm cytoskeleton transcription from RNA polymerase III promoter RNA splicing response to virus interspecies interaction between organisms
205726_at	-0.710	6.840	-2.777	1.396e-02	0.246	-2.982	DIAPH2	diaphanous homolog 2 (Drosophila)	X	95826317, 95826317	NM_006729	1730	Xq21.33	Hs.226483 Hs.716101	14	cytokinesis actin binding receptor binding cytoplasm early endosome Golgi apparatus cytosol multicellular organismal development cellular component organization Rho GTPase binding actin cytoskeleton organization cell differentiation oogenesis	Regulation of actin cytoskeleton
206277_at	-0.585	7.066	-2.777	1.397e-02	0.246	-2.983	P2RY2	purinergic receptor P2Y, G-protein coupled, 2	11	72606991, 72607149	NM_002564	5029	11q13.5-q14.1	Hs.339	43	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane cellular ion homeostasis signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger purinergic nucleotide receptor activity, G-protein coupled	Neuroactive ligand-receptor interaction
227903_x_at	-0.272	4.755	-2.777	1.397e-02	0.246	-2.983	C19orf20	chromosome 19 open reading frame 20	19	458496	AI990682	91978	19p13.3	Hs.369613	6	cytoplasm centrosome cytoskeleton microtubule cilium microtubule basal body multicellular organismal development spermatogenesis flagellum cell differentiation axon dendrite cilium axoneme flagellar axoneme
218252_at	-0.673	5.045	-2.776	1.397e-02	0.246	-2.983	CKAP2	cytoskeleton associated protein 2	13	51927495	NM_018204	26586	13q14	Hs.444028 Hs.449585 Hs.711762	17	cytoplasm cytoskeleton microtubule apoptosis cell cycle
228753_at	-0.611	5.109	-2.776	1.397e-02	0.246	-2.983	LOC100128737	hypothetical LOC100128737	7		AI041217	100128737	7q22.3
209455_at	-0.394	7.651	-2.776	1.399e-02	0.246	-2.984	FBXW11	F-box and WD repeat domain containing 11	5	-171221160	BE963245	23291	5q35.1	Hs.484138	14	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding cytoplasm Wnt receptor signaling pathway protein ubiquitination modification-dependent protein catabolic process	Ubiquitin mediated proteolysis Wnt signaling pathway Hedgehog signaling pathway
201315_x_at	0.555	8.833	2.776	1.399e-02	0.246	-2.984	IFITM2	interferon induced transmembrane protein 2 (1-8D)	11	298106	NM_006435	10581	11p15.5	Hs.709321	6	protein binding immune response response to biotic stimulus membrane integral to membrane
238047_at	2.294	5.314	2.776	1.399e-02	0.246	-2.984	RP13-102H20.1	hypothetical protein FLJ30058	X	130019896	AA405456	158763	Xq26.1	Hs.22905	5	intracellular signal transduction
205934_at	-0.757	6.897	-2.776	1.399e-02	0.246	-2.985	PLCL1	phospholipase C-like 1	2	198377670, 198377777	NM_006226	5334	2q33	Hs.153322 Hs.593586	8	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
201146_at	-0.522	8.217	-2.775	1.400e-02	0.247	-2.985	NFE2L2	nuclear factor (erythroid-derived 2)-like 2	2	-177803279, -177803278	NM_006164	4780	2q31	Hs.715540	141	transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity
206398_s_at	0.342	4.807	2.775	1.402e-02	0.247	-2.986	CD19	CD19 molecule	16	28850760	NM_001770	930	16p11.2	Hs.652262	49	receptor signaling protein activity protein binding plasma membrane integral to plasma membrane cellular defense response cell surface receptor linked signal transduction external side of plasma membrane B cell receptor signaling pathway	Hematopoietic cell lineage B cell receptor signaling pathway Primary immunodeficiency
212851_at	-0.472	6.005	-2.775	1.402e-02	0.247	-2.986	DCUN1D4	DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)	4	52404032	AA194584	23142	4q12	Hs.605388	10	nucleus
200697_at	-0.404	9.866	-2.774	1.404e-02	0.247	-2.988	HK1	hexokinase 1	10	70699761, 70745615, 70748608	NM_000188	3098	10q22	Hs.370365	40	nucleotide binding hexokinase activity hexokinase activity ATP binding mitochondrion mitochondrial outer membrane cytosol cytosol carbohydrate metabolic process glycolysis membrane kinase activity transferase activity	Glycolysis / Gluconeogenesis Fructose and mannose metabolism Galactose metabolism Starch and sucrose metabolism Amino sugar and nucleotide sugar metabolism Streptomycin biosynthesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Insulin signaling pathway Type II diabetes mellitus
210243_s_at	-0.430	6.341	-2.774	1.405e-02	0.247	-2.988	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	1	-159407724	AF038661	8703	1q21-q23	Hs.321231	16	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity N-acetyllactosamine synthase activity cytoplasm Golgi apparatus carbohydrate metabolic process galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding metal ion binding	N-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
1558044_s_at	0.584	7.195	2.773	1.406e-02	0.247	-2.989	EXOSC6	exosome component 6	16	-68841634	BF692729	118460	16q22.1	Hs.660633 Hs.719211	9	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
224162_s_at	-0.668	7.935	-2.773	1.406e-02	0.247	-2.989	FBXO31	F-box protein 31	16	-85920444, -85920444	BC002985	79791	16q24.2	Hs.567582	10	cell cycle cyclin catabolic process SCF ubiquitin ligase complex modification-dependent protein catabolic process cyclin binding SCF-dependent proteasomal ubiquitin-dependent protein catabolic process G1 DNA damage checkpoint cellular response to DNA damage stimulus
209244_s_at	-0.287	8.255	-2.773	1.407e-02	0.247	-2.990	KIF1C	kinesin family member 1C	17	4841999	BE885926	10749	17p13.2	Hs.435120	8	nucleotide binding microtubule motor activity ATP binding endoplasmic reticulum Golgi apparatus microtubule retrograde vesicle-mediated transport, Golgi to ER microtubule-based movement
213027_at	-0.424	6.765	-2.773	1.407e-02	0.247	-2.990	TROVE2	TROVE domain family, member 2	1	191295375, 191295579, 191295579	AU146655	6738	1q31	Hs.288178	24	RNA binding protein binding cytoplasm transcription from RNA polymerase III promoter ribonucleoprotein complex	Systemic lupus erythematosus
202271_at	-0.353	7.657	-2.773	1.408e-02	0.247	-2.990	FBXO28	F-box protein 28	1	222368413	AB007952	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
201631_s_at	-0.565	6.178	-2.772	1.409e-02	0.247	-2.991	IER3	immediate early response 3	6	-30818954, -2159551, -1957851	NM_003897	8870	6p21.3	Hs.591785	37	protein binding apoptosis anti-apoptosis anatomical structure morphogenesis membrane integral to membrane
200867_at	-0.584	7.326	-2.771	1.412e-02	0.247	-2.993	RNF114	ring finger protein 114	20	47986320	AL031685	55905	20q13.13	Hs.144949	9	protein binding intracellular multicellular organismal development spermatogenesis zinc ion binding cell differentiation metal ion binding
223254_s_at	-0.402	4.410	-2.771	1.413e-02	0.247	-2.994	G2E3	G2/M-phase specific E3 ubiquitin ligase	14	30098079	AA887053	55632	14q12	Hs.509008 Hs.605081	13	protein polyubiquitination blastocyst development ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm Golgi apparatus protein modification process multicellular organismal development zinc ion binding ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process negative regulation of apoptosis metal ion binding
1566191_at	0.316	4.870	2.770	1.414e-02	0.247	-2.994	SUZ12	suppressor of zeste 12 homolog (Drosophila)	17	27288156	AI907884	23512	17q11.2	Hs.462732	31	intracellular nucleus zinc ion binding chromatin modification ESC/E(Z) complex histone methyltransferase activity regulation of transcription metal ion binding
205771_s_at	-0.887	7.942	-2.770	1.414e-02	0.247	-2.994	AKAP7	A kinase (PRKA) anchor protein 7	6	131508153, 131613196	AL137063	9465	6q23	Hs.486483	9	catalytic activity intracellular cytoplasm cytosol plasma membrane ion transport intracellular signaling cascade protein localization biological_process RNA metabolic process apical plasma membrane lateral plasma membrane protein kinase A binding protein kinase A binding
232366_at	-0.633	5.571	-2.770	1.415e-02	0.247	-2.994	KIAA0232	KIAA0232	4	6835359	AF143884	9778	4p16.1	Hs.79276	7	nucleotide binding ATP binding
1555543_a_at	-0.551	5.470	-2.770	1.415e-02	0.247	-2.994	CLCC1	chloride channel CLIC-like 1	1	-109273652	AB052917	23155	1p13.3	Hs.658489	6	nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane
203357_s_at	-0.709	5.769	-2.770	1.415e-02	0.247	-2.994	CAPN7	calpain 7	3	15222736	NM_014296	23473	3p24	Hs.631920	6	calcium-dependent cysteine-type endopeptidase activity intracellular nucleus proteolysis peptidase activity cysteine-type peptidase activity
217898_at	-0.385	8.557	-2.770	1.415e-02	0.247	-2.995	C15orf24	chromosome 15 open reading frame 24	15	-32163515	NM_020154	56851	15q14	Hs.160565	6	cytoplasm biological_process membrane integral to membrane purine nucleotide binding
201023_at	-0.512	9.598	-2.770	1.416e-02	0.247	-2.995	TAF7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	5	-140678240	NM_005642	6879	5q31	Hs.438838	38	spermine transport transcription factor activity transcription coactivator activity nucleus transcription factor TFIID complex nucleolus cytoplasm Golgi apparatus transcription initiation from RNA polymerase II promoter negative regulation of protein kinase activity positive transcription elongation factor complex b negative regulation of specific transcription from RNA polymerase II promoter promoter binding general RNA polymerase II transcription factor activity specific transcriptional repressor activity transcription initiation factor activity estrogen receptor signaling pathway transcription factor TFTC complex histone acetyltransferase binding negative regulation of histone acetylation vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding	Basal transcription factors
223985_at	-0.503	3.084	-2.770	1.416e-02	0.247	-2.995	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	AF316830	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
219457_s_at	0.368	5.367	2.770	1.416e-02	0.247	-2.995	RIN3	Ras and Rab interactor 3	14	92049877	NM_024832	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
232298_at	-0.949	7.873	-2.770	1.417e-02	0.247	-2.996	hCG_1806964	hypothetical LOC401093	3	-153463102	AK026494	401093	3q25.1	Hs.201858 Hs.558914 Hs.719379	3
205521_at	-0.550	5.928	-2.769	1.419e-02	0.247	-2.998	EXOG	endo/exonuclease (5'-3'), endonuclease G-like	3	38512766	BF511976	9941	3p21.3	Hs.517897	6	nucleic acid binding endonuclease activity cellular_component mitochondrion mitochondrial inner membrane biological_process membrane hydrolase activity metal ion binding	Apoptosis
227788_at	-0.534	8.148	-2.769	1.419e-02	0.247	-2.998	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	3	180853626	AW295324	8975	3q26.2-q26.3	Hs.175322	11	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding
241602_at	0.260	6.195	2.769	1.420e-02	0.247	-2.998	ZNF582	zinc finger protein 582	19	-61586459	BG432829	147948	19q13.43	Hs.244391	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235114_x_at	-0.476	3.985	-2.768	1.421e-02	0.247	-2.999	HOOK3	hook homolog 3 (Drosophila)	8	42871189	N67300	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
235515_at	0.330	3.510	2.768	1.421e-02	0.247	-2.999	C19orf46	chromosome 19 open reading frame 46	19	-41185841	AA827649	163183	19q13.12	Hs.436743	2	actin binding nucleus membrane integral to membrane
221522_at	-0.660	6.708	-2.768	1.422e-02	0.247	-2.999	ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	19	-37779746	AL136784	84079	19q13.11	Hs.59236	12	guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm lysosome early endosome early endosome to late endosome transport
1568644_at	0.298	2.618	2.768	1.422e-02	0.247	-2.999	ZNF208	zinc finger protein 208	19	-21940736	BC038199	7757	19p12	Hs.541334	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200828_s_at	-0.626	8.457	-2.768	1.422e-02	0.247	-2.999	ZNF207	zinc finger protein 207	17	27701269	BE871379	7756	17q11.2	Hs.500775	7	transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211170_s_at	-0.375	3.545	-2.768	1.422e-02	0.247	-2.999	PDE10A	phosphodiesterase 10A	6	-165660767	AF127480	10846	6q26	Hs.348762	13	nucleotide binding magnesium ion binding cytoplasm signal transduction zinc ion binding hydrolase activity cAMP binding cGMP binding 3',5'-cyclic-GMP phosphodiesterase activity	Purine metabolism
226876_at	0.533	7.080	2.768	1.423e-02	0.247	-3.000	FAM101B	family with sequence similarity 101, member B	17	-289998	AI961778	359845	17p13	Hs.345588 Hs.596411 Hs.719324	4
208809_s_at	-0.427	8.603	-2.767	1.423e-02	0.247	-3.000	C6orf62	chromosome 6 open reading frame 62	6	-24813069	AL136632	81688	6p22.3	Hs.519930	6	molecular_function cellular_component intracellular biological_process
210749_x_at	-0.659	7.205	-2.767	1.424e-02	0.247	-3.000	DDR1	discoidin domain receptor tyrosine kinase 1	6	30959839, 30960305, 30964443, 2300465, 2300931, 2305069, 2098794, 2099260, 2103398	L11315	780	6p21.3	Hs.631988	60	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding extracellular region integral to plasma membrane protein amino acid phosphorylation cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity
201581_at	-0.514	8.777	-2.767	1.425e-02	0.247	-3.001	TMX4	thioredoxin-related transmembrane protein 4	20	-7909715	BF572868	56255	20p12	Hs.169358	11	mitochondrion transport membrane integral to membrane electron transport chain cell redox homeostasis
232631_at	0.420	4.685	2.766	1.426e-02	0.247	-3.002	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	5	31229552	AU150574	1004	5p15.1-p14	Hs.171054	14	calcium ion binding protein binding nucleus cytoplasm plasma membrane cell adhesion homophilic cell adhesion female gonad development integral to membrane
201091_s_at	-0.521	7.916	-2.766	1.427e-02	0.247	-3.002	CBX3	chromobox homolog 3 (HP1 gamma homolog, Drosophila)	7	26207623, 26207848	BE748755	11335	7p15.2	Hs.381189 Hs.706294	45	condensed chromosome, centromeric region chromatin chromatin binding nucleus nuclear inner membrane polytene chromosome chromocenter nuclear euchromatin spindle chromatin assembly or disassembly chromatin remodeling negative regulation of transcription general transcriptional repressor activity enzyme binding protein domain specific binding nuclear centromeric heterochromatin
202983_at	0.437	7.487	2.766	1.427e-02	0.247	-3.002	HLTF	helicase-like transcription factor	3	-150230593	AI760760	6596	3q25.1-q26.1	Hs.3068	22	nucleotide binding DNA binding RNA polymerase II transcription factor activity helicase activity protein binding ATP binding nucleus transcription regulation of transcription from RNA polymerase II promoter zinc ion binding transcription activator activity chromatin modification hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity metal ion binding
208617_s_at	-0.683	10.462	-2.766	1.428e-02	0.247	-3.003	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	AF208850	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
221504_s_at	-0.514	7.538	-2.766	1.428e-02	0.247	-3.003	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	8	-54790667, -54790667	AF112204	51606	8q11.2	Hs.491737	20	vacuolar proton-transporting V-type ATPase, V1 domain protein binding cytosol plasma membrane ion transport endocytosis vacuolar acidification ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity enzyme regulator activity interspecies interaction between organisms proton-transporting ATPase activity, rotational mechanism regulation of defense response to virus by virus	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
225055_at	-0.392	6.036	-2.765	1.430e-02	0.248	-3.004	LOC651250	hypothetical LOC651250	17	63609332	AV735241	651250	17q24.2	Hs.293560 Hs.591212 Hs.647405 Hs.655146 Hs.663262	3
201399_s_at	-0.505	6.073	-2.765	1.431e-02	0.248	-3.005	TRAM1	translocation associated membrane protein 1	8	-71648226	NM_014294	23471	8q13.3	Hs.491988	9	receptor activity protein binding endoplasmic reticulum cotranslational protein targeting to membrane protein transport membrane integral to membrane intracellular protein transmembrane transport
225790_at	-0.683	7.260	-2.764	1.433e-02	0.248	-3.006	MSRB3	methionine sulfoxide reductase B3	12	63958754	AL048386	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
1559977_a_at	1.524	8.726	2.763	1.436e-02	0.248	-3.008	SLC25A34	solute carrier family 25, member 34	1	15935395	AL832282	284723	1p36.21	Hs.631867	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
226050_at	-1.051	6.706	-2.763	1.437e-02	0.248	-3.009	TMCO3	transmembrane and coiled-coil domains 3	13	113193308	AL576117	55002	13q34	Hs.317593	6	cation transport antiporter activity solute:hydrogen antiporter activity membrane integral to membrane
224359_s_at	-0.358	3.896	-2.762	1.438e-02	0.248	-3.009	HOOK3	hook homolog 3 (Drosophila)	8	42871189	AF241830	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
204366_s_at	-0.350	7.179	-2.762	1.439e-02	0.249	-3.010	GTF3C2	general transcription factor IIIC, polypeptide 2, beta 110kDa	2	-27402224	NM_001521	2976	2p23.3	Hs.75782	18	transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity protein binding nucleus mitochondrion peroxisome transcription, DNA-dependent oxygen and reactive oxygen species metabolic process 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter
213093_at	-0.596	7.094	-2.762	1.440e-02	0.249	-3.010	PRKCA	protein kinase C, alpha	17	61729387	AI471375	5578	17q22-q23.2	Hs.531704 Hs.708867	455	nucleotide binding inactivation of MAPK activity negative regulation of protein amino acid phosphorylation positive regulation of protein amino acid phosphorylation regulation of the force of heart contraction chondrocyte differentiation calcium-dependent protein kinase C activity calcium ion binding protein binding ATP binding membrane fraction nucleus cytoplasm mitochondrion cytosol cytosol plasma membrane negative regulation of protein kinase activity cellular calcium ion homeostasis regulation of muscle contraction intracellular signaling cascade zinc ion binding negative regulation of cell proliferation induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals transferase activity diacylglycerol binding neutrophil chemotaxis negative regulation of glucose import negative regulation of insulin receptor signaling pathway positive regulation of inflammatory response regulation of peptidyl-tyrosine phosphorylation induction of positive chemotaxis	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway VEGF signaling pathway Focal adhesion Tight junction Gap junction Natural killer cell mediated cytotoxicity Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Pathways in cancer Glioma Non-small cell lung cancer
218360_at	-0.369	6.059	-2.761	1.441e-02	0.249	-3.011	RAB22A	RAB22A, member RAS oncogene family	20	56318176	NM_020673	57403	20q13.32	Hs.529044	14	nucleotide binding GTPase activity protein binding protein binding GTP binding early endosome plasma membrane endocytosis endosome organization small GTPase mediated signal transduction protein transport	Endocytosis
238664_s_at	0.240	4.773	2.761	1.441e-02	0.249	-3.011	MGC12916	hypothetical protein MGC12916	17	14147781	BF205828	84815	17p12	Hs.597458
207988_s_at	-0.521	9.799	-2.760	1.443e-02	0.249	-3.013	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	2	218790118, 218790364	NM_005731	10109	2q36.1	Hs.529303	23	actin binding structural constituent of cytoskeleton protein binding cytoplasm Golgi apparatus Arp2/3 protein complex focal adhesion cell motion positive regulation of actin filament polymerization cell leading edge cell projection	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
222863_at	-0.292	3.144	-2.760	1.444e-02	0.249	-3.013	ZBTB10	zinc finger and BTB domain containing 10	8	81561002	BG483802	65986	8q13-q21.1	Hs.591868	4	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
237833_s_at	0.317	5.311	2.760	1.444e-02	0.249	-3.013	SNCAIP	synuclein, alpha interacting protein	5	121675718	BF062366	9627	5q23.1-q23.3	Hs.426463	40	protein binding cytoplasm dopamine metabolic process presynaptic membrane cell soma regulation of neurotransmitter secretion	Parkinson's disease
230822_at	0.328	4.496	2.760	1.444e-02	0.249	-3.013	TMEM61	transmembrane protein 61	1	55219052	AI766925	199964	1p32.3	Hs.663950	3	membrane integral to membrane
201007_at	0.465	12.162	2.760	1.445e-02	0.249	-3.014	HADHB	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	2	26321119	NM_000183	3032	2p23	Hs.515848	23	3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity mitochondrion mitochondrial envelope mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process acyltransferase activity transferase activity mitochondrial nucleoid	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Metabolic pathways
214370_at	-0.533	2.682	-2.759	1.446e-02	0.249	-3.014	S100A8	S100 calcium binding protein A8	1	-151629131	AW238654	6279	1q21	Hs.416073	91	calcium ion binding protein binding inflammatory response
1554462_a_at	-0.810	7.075	-2.759	1.446e-02	0.249	-3.014	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	AF115512	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
218857_s_at	0.499	6.547	2.759	1.447e-02	0.249	-3.015	ASRGL1	asparaginase like 1	11	61861349	NM_025080	80150	11q12.3	Hs.535326	9	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity cytoplasm hydrolase activity asparagine catabolic process via L-aspartate	Alanine, aspartate and glutamate metabolism Cyanoamino acid metabolism Nitrogen metabolism Metabolic pathways
209142_s_at	-0.713	10.214	-2.759	1.447e-02	0.249	-3.015	UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	17	-4119260	BC002775	7326	17p13.2 1q42	Hs.714345	12	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
213394_at	0.397	6.371	2.759	1.449e-02	0.249	-3.016	MAPKBP1	mitogen-activated protein kinase binding protein 1	15	39853923	AI674759	23005	15q15.1	Hs.513661	6
213019_at	-0.397	7.854	-2.758	1.450e-02	0.249	-3.017	RANBP6	RAN binding protein 6	9	-6001019, -6001018	AI123233	26953	9p24.1	Hs.167496 Hs.675725	5	binding nucleus cytoplasm protein transport
228909_at	0.312	4.595	2.758	1.450e-02	0.249	-3.017	LOC642852	hypothetical LOC642852	21	45532394	AW131553	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
203208_s_at	-0.319	7.452	-2.758	1.451e-02	0.249	-3.017	MTFR1	mitochondrial fission regulator 1	8	66719441, 66719441, 66744661	NM_014637	9650	8q13.1	Hs.584788	8	mitochondrion plasma membrane
208841_s_at	-0.650	9.625	-2.758	1.451e-02	0.249	-3.017	G3BP2	GTPase activating protein (SH3 domain) binding protein 2	4	-76786976, -76786976	AB014560	9908	4q21.1	Hs.303676	15	nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport
217902_s_at	-0.328	8.060	-2.757	1.453e-02	0.249	-3.018	HERC2	hect domain and RLD 2	15	-26029782	NM_004667	8924	15q13	Hs.434890 Hs.610412	24	ubiquitin-protein ligase activity guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular anaphase-promoting complex protein modification process intracellular protein transport zinc ion binding protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process heme binding regulation of mitotic metaphase/anaphase transition metal ion binding	Ubiquitin mediated proteolysis
225915_at	-1.030	5.996	-2.757	1.453e-02	0.249	-3.019	CAB39L	calcium binding protein 39-like	13	-48780786, -48780786	AL138875	81617	13q14.2	Hs.87159	9	protein binding	mTOR signaling pathway
223298_s_at	0.679	10.065	2.757	1.454e-02	0.249	-3.019	NT5C3	5'-nucleotidase, cytosolic III	7	-33020266, -33020266	AF312735	51251	7p14.3	Hs.487933	22	nucleotide binding magnesium ion binding cytoplasm endoplasmic reticulum pyrimidine nucleoside metabolic process 5'-nucleotidase activity 5'-nucleotidase activity 2'-phosphotransferase activity 2'-phosphotransferase activity nucleotide metabolic process hydrolase activity	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
227179_at	-0.395	8.385	-2.757	1.455e-02	0.249	-3.020	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)	8	-74624394	AK002152	27067	8q13-q21.1	Hs.561815	11	double-stranded RNA binding intracellular nucleus nucleolus cytoplasm endoplasmic reticulum microtubule transport
220664_at	0.267	3.974	2.755	1.459e-02	0.249	-3.022	SPRR2C	small proline-rich protein 2C (pseudogene)	1	-151379217	NM_006518	6702	1q21-q22	Hs.2421	5
216344_at	0.304	4.282	2.754	1.462e-02	0.250	-3.024	NPHP4	nephronophthisis 4	1	-5845456	AL117405	261734	1p36.22	Hs.462348	13	structural molecule activity protein binding centrosome cilium microtubule basal body signal transduction visual behavior membrane cell-cell adhesion actin cytoskeleton organization
218097_s_at	0.299	9.332	2.754	1.463e-02	0.250	-3.025	CUEDC2	CUE domain containing 2	10	-104172991	NM_024040	79004	10q24.32	Hs.500874	6	protein binding nucleus cytoplasm modification-dependent protein catabolic process
244409_at	0.427	6.286	2.754	1.463e-02	0.250	-3.025	CCDC154	coiled-coil domain containing 154	16	-1424390	AW612232	645811	16p13.3	Hs.355232	1
224860_at	0.781	6.256	2.753	1.464e-02	0.250	-3.025	C9orf123	chromosome 9 open reading frame 123	9	-7786490	AL137489	90871	9p24.1	Hs.7517	4	membrane integral to membrane
1554960_at	0.248	3.382	2.753	1.464e-02	0.250	-3.026	C1orf110	chromosome 1 open reading frame 110	1	-161090710	BC040018	339512	1q23.3	Hs.407631	5
227192_at	0.319	4.884	2.753	1.467e-02	0.250	-3.027	PRRT2	proline-rich transmembrane protein 2	16	29730909	BF060707	112476	16p11.2	Hs.655071	5	response to biotic stimulus membrane integral to membrane
224931_at	-0.364	7.334	-2.752	1.467e-02	0.250	-3.027	SLC41A3	solute carrier family 41, member 3	3	-127207889, -127207889	AK021925	54946	3q21.2-q21.3	Hs.573007	5	plasma membrane cation transport cation transmembrane transporter activity integral to membrane
235863_at	-0.411	6.936	-2.752	1.468e-02	0.250	-3.028	JSRP1	junctional sarcoplasmic reticulum protein 1	19	-2203251	AI805145	126306	19p13.3	Hs.712901	4	membrane sarcoplasmic reticulum membrane
222612_at	-0.576	4.881	-2.751	1.471e-02	0.250	-3.029	PSPC1	paraspeckle component 1	13	-19175008, -19146895	N32583	55269	13q12.11	Hs.213198	9	nucleotide binding RNA binding protein binding nucleus nucleolus cytoplasm nuclear matrix regulation of transcription
234192_s_at	-0.538	8.574	-2.751	1.471e-02	0.250	-3.030	GKAP1	G kinase anchoring protein 1	9	-85544156	AK026487	80318	9q21.32	Hs.522255	5	protein binding Golgi apparatus signal transduction
1556536_at	0.286	3.835	2.751	1.471e-02	0.250	-3.030	hCG_2044152	hCG2044152	2		BC040292	729224	2q33.1	Hs.623895	1
1556667_at	-1.063	5.469	-2.751	1.472e-02	0.250	-3.030	LOC348751	hypothetical protein LOC348751	2		BC039445	348751	2q33.1	Hs.471039	1
231899_at	-0.641	7.558	-2.750	1.473e-02	0.250	-3.031	ZC3H12C	zinc finger CCCH-type containing 12C	11	109469296	AB051513	85463	11q22.3	Hs.376289	3	magnesium ion binding endonuclease activity zinc ion binding hydrolase activity
219656_at	0.304	6.482	2.750	1.474e-02	0.251	-3.032	PCDH12	protocadherin 12	5	-141304713	NM_016580	51294	5q31	Hs.439474	10	calcium ion binding protein binding plasma membrane integral to plasma membrane cell-cell junction cell adhesion homophilic cell adhesion neuron recognition calcium-dependent cell-cell adhesion
227937_at	0.353	6.426	2.750	1.474e-02	0.251	-3.032	MYPOP	Myb-related transcription factor, partner of profilin	19	-51085120	AA307731	339344	19q13.32	Hs.515478	2	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus protein homodimerization activity regulation of transcription
220975_s_at	0.251	6.295	2.749	1.476e-02	0.251	-3.033	C1QTNF1	C1q and tumor necrosis factor related protein 1	17	74531845, 74542066	NM_030968	114897	17q25.3	Hs.201398	11	extracellular region
226220_at	-0.358	5.644	-2.749	1.477e-02	0.251	-3.033	METTL9	methyltransferase like 9	16	21518356	BE551054	51108	16p13-p12	Hs.279583	6
215447_at	0.511	3.836	2.748	1.479e-02	0.251	-3.034	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	2	-188051550, -188037202	AL080215	7035	2q32	Hs.516578	118	serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway	Complement and coagulation cascades
211084_x_at	-0.306	5.254	-2.748	1.479e-02	0.251	-3.035	PRKD3	protein kinase D3	2	-37331149	Z25429	23683	2p21	Hs.660757 Hs.716034	31	nucleotide binding protein kinase C activity protein binding ATP binding protein amino acid phosphorylation activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding metal ion binding
204830_x_at	0.410	4.280	2.748	1.480e-02	0.251	-3.035	PSG5	pregnancy specific beta-1-glycoprotein 5	19	-48363734	NM_002781	5673	19q13.2	Hs.654415	15	extracellular region female pregnancy
233919_s_at	-0.286	6.234	-2.748	1.481e-02	0.251	-3.036	HABP4	hyaluronan binding protein 4	9	98252234	BF213501	22927	9q22.3-q31	Hs.494567	15	nucleus cytoplasm regulation of transcription
209510_at	-0.434	8.058	-2.748	1.481e-02	0.251	-3.036	RNF139	ring finger protein 139	8	125556188	AF064801	11236	8q24	Hs.492751	10	receptor activity protein binding endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process regulation of protein ubiquitination metal ion binding
202915_s_at	-0.497	6.998	-2.747	1.482e-02	0.251	-3.036	FAM20B	family with sequence similarity 20, member B	1	177261696	BF115776	9917	1q25	Hs.719217	9	extracellular region
1552257_a_at	-0.290	5.887	-2.747	1.482e-02	0.251	-3.037	TTLL12	tubulin tyrosine ligase-like family, member 12	22	-41892571	NM_015140	23170	22q13.31	Hs.517670	6	tubulin-tyrosine ligase activity protein modification process
221433_at	1.656	5.684	2.747	1.484e-02	0.251	-3.037	FGF21	fibroblast growth factor 21	19	53951155	NM_019113	26291	19q13.1-qter	Hs.283015	17	extracellular region soluble fraction signal transduction cell-cell signaling growth factor activity	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
1565559_at	0.398	5.365	2.746	1.486e-02	0.251	-3.039	MAGIX	MAGI family member, X-linked	X	48906124, 48907213	AW418579	79917	Xp11.23	Hs.193170	3	protein binding
217096_at	0.360	4.613	2.746	1.486e-02	0.251	-3.039	PCLO	piccolo (presynaptic cytomatrix protein)	7	-82287731, -82221256	AC004082	27445	7q11.23-q21.3	Hs.12376	14	transporter activity calcium ion binding profilin binding calcium-dependent phospholipid binding cytoskeleton transport cytoskeleton organization synaptic vesicle zinc ion binding membrane synaptic vesicle exocytosis regulation of exocytosis cAMP-mediated signaling cell junction insulin secretion synapse
208135_at	0.283	4.231	2.746	1.487e-02	0.251	-3.039	HNF1B	HNF1 homeobox B	17	-33120546	NM_006481	6928	17cen-q21.3	Hs.191144	87	kidney development transcription factor activity nucleus nucleolus transcription activator activity sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Maturity onset diabetes of the young
212163_at	-0.547	6.725	-2.746	1.487e-02	0.251	-3.039	KIDINS220	kinase D-interacting substrate, 220kDa	2	-8786437	AB033076	57498	2p24	Hs.9873	17	cytosol intracellular signaling cascade membrane integral to membrane	Neurotrophin signaling pathway
208950_s_at	0.528	6.530	2.745	1.488e-02	0.251	-3.040	ALDH7A1	aldehyde dehydrogenase 7 family, member A1	5	-125906816	BC002515	501	5q31	Hs.483239	19	aldehyde dehydrogenase (NAD) activity L-aminoadipate-semialdehyde dehydrogenase activity cellular_component mitochondrion cellular aldehyde metabolic process sensory perception of sound oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
211514_at	0.342	3.691	2.745	1.488e-02	0.251	-3.040	DSTYK	dual serine/threonine and tyrosine protein kinase	1	-203378254	AF068286	25778	1q32.1	Hs.6874	9	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
201071_x_at	-0.355	9.823	-2.745	1.489e-02	0.251	-3.040	SF3B1	splicing factor 3b, subunit 1, 155kDa	2	-197991765, -197964942	NM_012433	23451	2q33.1	Hs.632554	34	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome protein binding nucleus spliceosomal complex RNA splicing nuclear speck RNA splicing factor activity, transesterification mechanism
231940_at	0.514	6.712	2.745	1.489e-02	0.251	-3.041	ZNF529	zinc finger protein 529	19	-41762996, -41726357, -41726357	AI369933	57711	19q13.13	Hs.708146	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229587_at	0.301	6.369	2.745	1.489e-02	0.251	-3.041	UBA2	ubiquitin-like modifier activating enzyme 2	19	39611107	AA974493	10054	19q12	Hs.631580	23	nucleotide binding ATP binding nucleus protein modification process enzyme activator activity transcription factor binding small protein activating enzyme activity ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
235313_at	-0.985	11.573	-2.745	1.490e-02	0.251	-3.041	NRAP	nebulin-related anchoring protein	10	-115338572	AA195854	4892	10q24-q26	Hs.268788	14	actin binding actin binding protein binding fascia adherens muscle tendon junction biological_process zinc ion binding metal ion binding muscle alpha-actinin binding
235692_at	0.567	5.955	2.744	1.491e-02	0.251	-3.042	SH3KBP1	SH3-domain kinase binding protein 1	X	-19462003, -19462003	AW024527	30011	Xp22.1-p21.3	Hs.719268	58	molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse	Endocytosis
216854_at	0.298	4.603	2.744	1.491e-02	0.251	-3.042	GDF11	growth differentiation factor 11	12	54423330	AF028333	10220	12q13.2	Hs.600883	10	skeletal system development ureteric bud development cytokine activity protein binding extracellular region extracellular space nervous system development mesoderm development growth factor activity negative regulation of cell proliferation organ morphogenesis spinal cord anterior/posterior patterning pancreas development growth negative regulation of cell differentiation cell maturation camera-type eye morphogenesis
219196_at	0.225	2.063	2.744	1.492e-02	0.251	-3.042	SCG3	secretogranin III	15	49760841	NM_013243	29106	15q21	Hs.232618	16	extracellular region
227511_at	0.278	5.267	2.744	1.492e-02	0.251	-3.043	SAMD4B	sterile alpha motif domain containing 4B	19	44524947	BE963280	55095	19q13.2	Hs.612332	8	protein binding
220129_at	0.991	4.303	2.743	1.494e-02	0.252	-3.044	SOHLH2	spermatogenesis and oogenesis specific basic helix-loop-helix 2	13	-35640346	NM_017826	54937	13q13.3	Hs.124519	4	DNA binding nucleus multicellular organismal development spermatogenesis cell differentiation transcription regulator activity regulation of transcription oogenesis
221234_s_at	-0.681	4.931	-2.743	1.496e-02	0.252	-3.045	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	6	-90692968	NM_021813	60468	6q15	Hs.269764 Hs.716609 Hs.716710	23	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
227055_at	-1.072	6.216	-2.743	1.496e-02	0.252	-3.045	METTL7B	methyltransferase like 7B	12	54361596	AI827972	196410	12q13.2	Hs.51483	3	metabolic process methyltransferase activity transferase activity
218219_s_at	-0.394	5.689	-2.742	1.498e-02	0.252	-3.046	LANCL2	LanC lantibiotic synthetase component C-like 2 (bacterial)	7	55400634	NM_018697	55915	7q31.1-q31.33	Hs.595384 Hs.655117	9	catalytic activity ATP binding GTP binding nucleus cytoplasm cytosol plasma membrane negative regulation of transcription
209659_s_at	-0.400	8.563	-2.742	1.498e-02	0.252	-3.046	CDC16	cell division cycle 16 homolog (S. cerevisiae)	13	114018463	AF164598	8881	13q34	Hs.374127	32	binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
1561847_at	0.417	4.429	2.742	1.499e-02	0.252	-3.047	NUDT17	nudix (nucleoside diphosphate linked moiety X)-type motif 17	1	-144297851	AA481984	200035	1q21.1	Hs.585066	4	magnesium ion binding mitochondrion hydrolase activity manganese ion binding
1554628_at	0.553	3.887	2.741	1.500e-02	0.252	-3.047	ZNF57	zinc finger protein 57	19	2851895	BC028974	126295	19p13.3	Hs.591378	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
223776_x_at	-0.407	7.357	-2.741	1.500e-02	0.252	-3.047	TINF2	TERF1 (TRF1)-interacting nuclear factor 2	14	-23778690	BC005030	26277	14q12	Hs.496191	30	chromosome, telomeric region nuclear telomere cap complex DNA binding nucleus nucleoplasm chromosome protein C-terminus binding perinucleolar chromocenter telomere maintenance via telomere lengthening negative regulation of protein amino acid ADP-ribosylation telomere assembly positive regulation of telomere maintenance negative regulation of telomere maintenance via telomerase negative regulation of telomere maintenance via telomerase telomeric DNA binding negative regulation of epithelial cell proliferation protein localization to telomere
224806_at	0.656	6.930	2.741	1.500e-02	0.252	-3.048	TRIM25	tripartite motif-containing 25	17	-52320268	BE563152	7706	17q23.2	Hs.528952	22	transcription factor activity protein binding nucleus nucleolus cytoplasm focal adhesion zinc ion binding cell junction metal ion binding	RIG-I-like receptor signaling pathway
202514_at	-0.622	5.772	-2.741	1.501e-02	0.252	-3.048	DLG1	discs, large homolog 1 (Drosophila)	3	-198253827	AW139131	1739	3q29	Hs.292549	95	endothelial cell proliferation guanylate kinase activity phosphoprotein phosphatase activity endoplasmic reticulum endoplasmic reticulum membrane cell-cell junction actin filament organization establishment or maintenance of cell polarity protein C-terminus binding cytoskeletal protein binding postsynaptic density potassium channel regulator activity basolateral plasma membrane cell-cell adhesion protein kinase binding phosphatase binding cortical actin cytoskeleton organization G1/S transition checkpoint sarcolemma interspecies interaction between organisms synapse postsynaptic membrane negative regulation of mitotic cell cycle	T cell receptor signaling pathway
219913_s_at	-0.569	6.603	-2.741	1.501e-02	0.252	-3.048	CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)	20	-19963011	NM_016652	51340	20p11.2	Hs.171342	7	spliceosome assembly RNA binding intracellular nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing nuclear speck
206122_at	0.350	6.436	2.741	1.502e-02	0.252	-3.048	SOX15	SRY (sex determining region Y)-box 15	17	-7432221	NM_006942	6665	17p13	Hs.95582	13	negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm chromatin organization male gonad development cell differentiation skeletal muscle regeneration negative regulation of striated muscle development positive regulation of transcription from RNA polymerase II promoter myoblast development
231812_x_at	-0.325	7.365	-2.740	1.503e-02	0.252	-3.049	PHAX	phosphorylated adaptor for RNA export	5	125964531	AK023255	51808	5q23.2	Hs.555731 Hs.719165	10	spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol snRNA export from nucleus Cajal body protein transport
211676_s_at	-1.011	6.362	-2.739	1.506e-02	0.252	-3.051	IFNGR1	interferon gamma receptor 1	6	-137560313	AF056979	3459	6q23.3	Hs.520414	104	receptor activity interferon-gamma receptor activity integral to plasma membrane signal transduction response to virus membrane cytokine binding	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity
205047_s_at	2.524	6.156	2.739	1.509e-02	0.253	-3.052	ASNS	asparagine synthetase	7	-97319376, -97319376	NM_001673	440	7q21.3	Hs.489207	36	nucleotide binding asparagine synthase (glutamine-hydrolyzing) activity asparagine synthase (glutamine-hydrolyzing) activity ATP binding soluble fraction cytosol asparagine biosynthetic process glutamine metabolic process metabolic process cellular amino acid biosynthetic process ligase activity cellular response to glucose starvation negative regulation of apoptosis positive regulation of mitotic cell cycle	Alanine, aspartate and glutamate metabolism Nitrogen metabolism Metabolic pathways
200033_at	-0.547	9.789	-2.738	1.510e-02	0.253	-3.053	DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	17	-59924835	NM_004396	1655	17q21	Hs.279806	50	nucleotide binding RNA binding RNA helicase activity protein binding ATP binding nucleus spliceosomal complex nucleolus mRNA processing ATP-dependent helicase activity RNA splicing cell growth hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
223169_s_at	-0.456	5.662	-2.738	1.510e-02	0.253	-3.053	RHOU	ras homolog gene family, member U	1	226937491	AB051826	58480	1q42.11-q42.3	Hs.647774	12	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding podosome GTPase activity protein binding GTP binding intracellular Golgi apparatus plasma membrane focal adhesion small GTPase mediated signal transduction regulation of cell shape Rac protein signal transduction actin cytoskeleton organization cell junction cell projection
212302_at	-0.511	6.571	-2.738	1.511e-02	0.253	-3.054	RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	15	39496593	AI192081	23168	15q15.1	Hs.511096	9	DNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm transcription initiation histone modification regulation of transcription
225125_at	-0.370	8.006	-2.737	1.512e-02	0.253	-3.054	MMGT1	membrane magnesium transporter 1	X	-134871896	BF978280	93380	Xq26.3	Hs.110702	7	magnesium ion binding cytoplasm early endosome endoplasmic reticulum Golgi apparatus plasma membrane transport cobalt ion transport copper ion transport cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity magnesium ion transmembrane transporter activity ferrous iron transport magnesium ion transport integral to membrane
217843_s_at	-0.403	7.886	-2.737	1.513e-02	0.253	-3.055	MED4	mediator complex subunit 4	13	-47548092	NM_014166	29079	13q14.2	Hs.181112	21	transcription cofactor activity receptor activity protein binding nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription activator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription thyroid hormone receptor binding
205682_x_at	0.369	6.181	2.737	1.513e-02	0.253	-3.055	APOM	apolipoprotein M	6	31731649, 3069795, 2871254	NM_019101	55937	6p21.33	Hs.534468	38	lipid transporter activity protein binding extracellular region cytosol integral to plasma membrane lipid transport defense response response to unfolded protein response to nutrient cholesterol efflux cholesterol efflux very-low-density lipoprotein particle low-density lipoprotein particle discoidal high-density lipoprotein particle spherical high-density lipoprotein particle high-density lipoprotein particle remodeling high-density lipoprotein particle assembly high-density lipoprotein particle clearance lipoprotein metabolic process cholesterol homeostasis protein complex reverse cholesterol transport NF-kappaB binding negative regulation of lipoprotein lipid oxidation
209036_s_at	0.277	12.037	2.737	1.514e-02	0.253	-3.056	MDH2	malate dehydrogenase 2, NAD (mitochondrial)	7	75515328	BC001917	4191	7cen-q22	Hs.520967	26	binding mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix glycolysis tricarboxylic acid cycle malate metabolic process malate metabolic process oxidoreductase activity L-malate dehydrogenase activity L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
223477_s_at	0.409	7.142	2.737	1.515e-02	0.253	-3.056	C12orf65	chromosome 12 open reading frame 65	12	122283793, 122284254	AF061733	91574	12q24.31	Hs.319128	2	translation release factor activity translational termination
226782_at	0.747	9.912	2.736	1.516e-02	0.253	-3.057	SLC25A30	solute carrier family 25, member 30	13	-44865455	BF001919	253512	13q14.13	Hs.591230	3	binding mitochondrion mitochondrial inner membrane transport mitochondrial transport membrane integral to membrane
1565698_at	0.340	2.355	2.736	1.517e-02	0.253	-3.057	HECTD2	HECT domain containing 2	10	93160075, 93160075	AI949651	143279	10q23.32	Hs.596096	7	intracellular protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process
226929_at	0.367	6.060	2.735	1.519e-02	0.253	-3.058	MTHFR	5,10-methylenetetrahydrofolate reductase (NADPH)	1	-11768373	AA524272	4524	1p36.3	Hs.214142	1776	methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction	One carbon pool by folate Methane metabolism Metabolic pathways
212333_at	-0.433	8.992	-2.735	1.519e-02	0.253	-3.058	FAM98A	family with sequence similarity 98, member A	2	-33662232	AL049943	25940	2p22.3	Hs.468140	2
1569034_a_at	0.271	2.968	2.734	1.521e-02	0.254	-3.060	LOC440864	hypothetical gene supported by BC040724	2		BC019620	440864	2p16.3	Hs.388171	1
228372_at	0.384	6.539	2.734	1.522e-02	0.254	-3.060	C10orf128	chromosome 10 open reading frame 128	10	-50033896	AW204712	170371	10q11.23	Hs.385493	1	membrane integral to membrane
202778_s_at	-0.383	6.655	-2.734	1.524e-02	0.254	-3.061	ZMYM2	zinc finger, MYM-type 2	13	19430809	NM_003453	7750	13q11-q12	Hs.644041	29	protein binding cellular_component nucleus biological_process zinc ion binding PML body ubiquitin conjugating enzyme binding regulation of transcription metal ion binding
216064_s_at	-0.674	5.354	-2.733	1.525e-02	0.254	-3.062	AGA	aspartylglucosaminidase	4	-178588917	W27131	175	4q32-q33	Hs.207776	36	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity lysosome protein deglycosylation hydrolase activity protein maturation	Other glycan degradation Lysosome
1558212_at	0.595	5.993	2.733	1.526e-02	0.254	-3.062	FLJ35024	hypothetical LOC401491	9	-2525654	BC004474	401491	9p24.2	Hs.416043	2
222162_s_at	-1.312	6.709	-2.733	1.526e-02	0.254	-3.063	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	21	-27130476	AK023795	9510	21q21.2	Hs.643357	44	ovulation from ovarian follicle kidney development metalloendopeptidase activity protein binding extracellular region basement membrane proteolysis integrin-mediated signaling pathway heparin binding peptidase activity zinc ion binding negative regulation of cell proliferation cytoplasmic vesicle metal ion binding heart trabecula formation
226618_at	-0.739	7.177	-2.733	1.526e-02	0.254	-3.063	FLJ25076	probable ubiquitin-conjugating enzyme E2 FLJ25076	5	6501735	AW572911	134111	5p15.31	Hs.126856	3	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
202484_s_at	-0.405	7.103	-2.733	1.527e-02	0.254	-3.063	MBD2	methyl-CpG binding domain protein 2	18	-49983044, -49934572	AF072242	8932	18q21	Hs.25674	50	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter heterochromatin DNA binding chromatin binding satellite DNA binding mRNA binding nucleus nucleus cytoplasm methyl-CpG binding negative regulation of transcription transcription repressor activity positive regulation of Wnt receptor signaling pathway siRNA binding regulation of cell proliferation maternal behavior cellular protein complex assembly C2H2 zinc finger domain binding
218864_at	-0.369	6.337	-2.732	1.528e-02	0.254	-3.064	TNS1	tensin 1	2	-218372756	AF116610	7145	2q35-q36	Hs.471381	16	actin binding protein binding cytoplasm cytoskeleton focal adhesion cell junction
228375_at	-0.851	5.406	-2.732	1.529e-02	0.254	-3.065	IGSF11	immunoglobulin superfamily, member 11	3	-120102168, -120102168	BE221674	152404	3q13.32	Hs.112873	7	receptor activity protein binding plasma membrane cell adhesion integral to membrane regulation of growth
220819_at	0.226	5.801	2.732	1.530e-02	0.254	-3.065	FRMD1	FERM domain containing 1	6	-168199312, -168199312	NM_024919	79981	6q27	Hs.266746	2	binding cytoskeleton
201841_s_at	-0.746	11.444	-2.731	1.531e-02	0.254	-3.065	HSPB1	heat shock 27kDa protein 1	7	75769810	NM_001540	3315	7q11.23	Hs.520973	153	nucleus cytoplasm spindle cytoskeleton regulation of translational initiation anti-apoptosis cell motion response to unfolded protein cell death response to heat cell surface identical protein binding	MAPK signaling pathway VEGF signaling pathway
1552395_at	0.345	6.430	2.730	1.535e-02	0.255	-3.068	TSSK3	testis-specific serine kinase 3	1	32600448	NM_052841	81629	1p35-p34	Hs.512763	5	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation multicellular organismal development spermatogenesis transferase activity cell differentiation
202038_at	-0.468	8.304	-2.729	1.536e-02	0.255	-3.069	UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)	11	117735511	NM_004788	9354	11q23.3	Hs.602967 Hs.75275	12	ubiquitin ligase complex protein polyubiquitination protein binding cytoplasm ubiquitin-dependent protein catabolic process ubiquitin-ubiquitin ligase activity	Ubiquitin mediated proteolysis
204117_at	-0.394	8.773	-2.729	1.537e-02	0.255	-3.069	PREP	prolyl endopeptidase	6	-105832198	NM_002726	5550	6q22	Hs.436564	26	serine-type endopeptidase activity cytoplasm proteolysis peptidase activity
224787_s_at	-0.628	7.976	-2.728	1.540e-02	0.255	-3.071	RAB18	RAB18, member RAS oncogene family	10	27833254	AI333232	22931	10p12.1	Hs.406799	24	nucleotide binding GTPase activity GTP binding cellular_component intracellular plasma membrane endocytosis small GTPase mediated signal transduction protein transport
217838_s_at	-0.467	6.515	-2.728	1.541e-02	0.255	-3.072	EVL	Enah/Vasp-like	14	99601503	NM_016337	51466	14q32.2	Hs.125867	24	actin binding profilin binding cytoplasm cytoskeleton focal adhesion cell surface receptor linked signal transduction nervous system development actin polymerization or depolymerization organ morphogenesis SH3 domain binding lamellipodium
223049_at	-0.393	7.509	-2.728	1.542e-02	0.255	-3.072	GRB2	growth factor receptor-bound protein 2	17	-70825751, -70825751	AF246238	2885	17q24-q25	Hs.444356 Hs.708119	438	SH3/SH2 adaptor activity epidermal growth factor receptor binding Golgi apparatus cytosol cytosol epidermal growth factor receptor signaling pathway Ras protein signal transduction Ras protein signal transduction cell-cell signaling insulin receptor signaling pathway insulin receptor substrate binding interspecies interaction between organisms	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
214648_at	0.335	3.631	2.727	1.543e-02	0.255	-3.073	GPX5	glutathione peroxidase 5 (epididymal androgen-related protein)	6	28601767	AI207120	2880	6p22.1	Hs.248129	14	glutathione peroxidase activity extracellular region lipid metabolic process response to oxidative stress oxidoreductase activity oxidation reduction	Glutathione metabolism Arachidonic acid metabolism
243481_at	0.309	4.148	2.726	1.546e-02	0.256	-3.074	RHOJ	ras homolog gene family, member J	14	62740897	AA181207	57381	14q23.2	Hs.656339	8	nucleotide binding GTPase activity protein binding GTP binding cellular_component intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape actin cytoskeleton organization
218761_at	-0.445	7.007	-2.726	1.547e-02	0.256	-3.075	RNF111	ring finger protein 111	15	57067156	NM_017610	54778	15q21	Hs.404423	13	protein binding nucleus cytoplasm multicellular organismal development zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
203528_at	-0.461	4.923	-2.726	1.548e-02	0.256	-3.076	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	9	-91181971, -91165525	NM_006378	10507	9q22.2	Hs.494406	29	receptor activity receptor binding anti-apoptosis immune response cell adhesion multicellular organismal development nervous system development membrane integral to membrane cell differentiation positive regulation of axonogenesis	Axon guidance
235068_at	-0.530	4.762	-2.725	1.550e-02	0.256	-3.077	ZDHHC21	zinc finger, DHHC-type containing 21	9	-14607032	AI807206	340481	9p22.3	Hs.649522	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
202698_x_at	0.339	12.077	2.725	1.550e-02	0.256	-3.077	COX4I1	cytochrome c oxidase subunit IV isoform 1	16	84390696	NM_001861	1327	16q22-qter	Hs.433419	17	cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
237465_at	-0.487	6.427	-2.725	1.550e-02	0.256	-3.077	USP53	ubiquitin specific peptidase 53	4	120353229	BF196943	54532	4q26	Hs.431081 Hs.595368	8	ubiquitin thiolesterase activity cellular_component ubiquitin-dependent protein catabolic process biological_process
209209_s_at	-0.454	6.661	-2.725	1.550e-02	0.256	-3.077	FERMT2	fermitin family homolog 2 (Drosophila)	14	-52395956, -52393739	AW469573	10979	14q22.1	Hs.509343	12	stress fiber protein binding cytoplasm cytoskeleton focal adhesion cell cortex cell adhesion regulation of cell shape actin cytoskeleton organization cell junction filamentous actin
211721_s_at	0.364	3.175	2.725	1.551e-02	0.256	-3.077	ZNF551	zinc finger protein 551	19	62885168	BC005868	90233	19q13.43	Hs.109540	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221562_s_at	0.496	6.794	2.725	1.551e-02	0.256	-3.077	SIRT3	sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)	11	-205029	AF083108	23410	11p15.5	Hs.716456	21	NAD+ ADP-ribosyltransferase activity protein binding cytoplasm mitochondrion mitochondrial matrix chromatin silencing protein amino acid ADP-ribosylation protein amino acid deacetylation zinc ion binding membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides regulation of transcription metal ion binding NAD binding
203057_s_at	-0.475	7.115	-2.725	1.552e-02	0.256	-3.078	PRDM2	PR domain containing 2, with ZNF domain	1	13899321, 13903936, 13903936, 13948462	AV724783	7799	1p36.21	Hs.371823	39	transcription factor activity intracellular nucleus Golgi apparatus regulation of transcription, DNA-dependent methyltransferase activity zinc ion binding transferase activity histone-lysine N-methyltransferase activity metal ion binding
209188_x_at	-0.409	6.894	-2.724	1.552e-02	0.256	-3.078	DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	1	93584065	BC002809	1810	1p22.1	Hs.348418	23	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity intracellular nucleus transcription factor binding sequence-specific DNA binding regulation of transcription
205508_at	-0.406	7.804	-2.724	1.553e-02	0.256	-3.079	SCN1B	sodium channel, voltage-gated, type I, beta	19	40213373, 40213373	NM_001037	6324	19q13.1	Hs.436646	28	voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport synaptic transmission membrane integral to membrane sodium ion binding
201730_s_at	-0.358	7.231	-2.724	1.554e-02	0.256	-3.079	TPR	translocated promoter region (to activated MET oncogene)	1	-184547408	BF110993	7175	1q25	Hs.279640	30	nucleotide binding kinetochore serine-tRNA ligase activity protein binding ATP binding nucleus nuclear pore nucleoplasm cytoplasm translation seryl-tRNA aminoacylation protein import into nucleus mitotic cell cycle spindle assembly checkpoint protein transport membrane mRNA transport intracellular protein transmembrane transport	Pathways in cancer Thyroid cancer
224761_at	-0.368	9.104	-2.724	1.554e-02	0.256	-3.079	GNA13	guanine nucleotide binding protein (G protein), alpha 13	17	-60435870	AI928136	10672	17q24.3	Hs.515018	57	nucleotide binding patterning of blood vessels in utero embryonic development GTPase activity signal transducer activity protein binding GTP binding cell motion signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade Rho protein signal transduction regulation of cell shape membrane guanyl nucleotide binding cell differentiation platelet activation regulation of cell migration melanosome	Vascular smooth muscle contraction Long-term depression Regulation of actin cytoskeleton
213434_at	-0.412	6.097	-2.724	1.555e-02	0.256	-3.079	STX2	syntaxin 2	12	-129840099	H95263	2054	12q24.33	Hs.437585	28	SNARE binding cytokinesis cell separation during cytokinesis SNAP receptor activity membrane fraction soluble fraction endosome microsome plasma membrane intracellular protein transport signal transduction acrosome reaction ectoderm development organ morphogenesis integral to membrane vesicle-mediated transport basolateral plasma membrane apical plasma membrane microvillus assembly midbody epithelial cell differentiation plasma membrane fusion calcium-dependent protein binding gut morphogenesis	SNARE interactions in vesicular transport
204629_at	0.384	6.712	2.723	1.556e-02	0.256	-3.080	PARVB	parvin, beta	22	42726505, 42751500	NM_013327	29780	22q13.2-q13.33	Hs.475074	18	actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion cell junction	Focal adhesion
215265_at	0.303	6.065	2.723	1.556e-02	0.256	-3.080	EMX1	empty spiracles homeobox 1	2	72998111	BF515060	2016	2p14-p13	Hs.516090	9	transcription factor activity nucleus regulation of transcription, DNA-dependent brain development post-embryonic development cerebral cortex development neuron differentiation response to drug sequence-specific DNA binding
235067_at	-0.559	6.451	-2.723	1.556e-02	0.256	-3.080	MKLN1	muskelin 1, intracellular mediator containing kelch motifs	7	130445394, 130663134	D81987	4289	7q32	Hs.44693	13	protein binding cytoplasm signal transduction
200927_s_at	-0.615	7.252	-2.723	1.557e-02	0.256	-3.081	RAB14	RAB14, member RAS oncogene family	9	-122980236	AA919115	51552	9q32-q34.11	Hs.371563 Hs.713585	19	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm
205151_s_at	-0.467	6.215	-2.723	1.557e-02	0.256	-3.081	KIAA0644	KIAA0644 gene product	7	-28959498	NM_014817	9865	7p14.3	Hs.719240	4	protein binding membrane integral to membrane
204497_at	-0.532	8.496	-2.722	1.558e-02	0.256	-3.082	ADCY9	adenylate cyclase 9	16	-3952652	AB011092	115	16p13.3	Hs.391860 Hs.610484	19	nucleotide binding magnesium ion binding adenylate cyclase activity ATP binding integral to plasma membrane cAMP biosynthetic process intracellular signaling cascade membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction GnRH signaling pathway Melanogenesis Vibrio cholerae infection
221527_s_at	-0.666	7.473	-2.721	1.563e-02	0.256	-3.084	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AF196185	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
206137_at	0.348	4.715	2.721	1.563e-02	0.256	-3.084	RIMS2	regulating synaptic membrane exocytosis 2	8	104582151, 104900591	NM_014677	9699	8q22.3	Hs.655271	18	protein binding plasma membrane intracellular protein transport zinc ion binding Rab GTPase binding cell junction synapse metal ion binding
205112_at	-0.768	4.586	-2.721	1.564e-02	0.256	-3.085	PLCE1	phospholipase C, epsilon 1	10	95743735	NM_016341	51196	10q23	Hs.655033	35	Golgi membrane activation of MAPK activity regulation of cell growth phosphoinositide phospholipase C activity receptor signaling protein activity guanyl-nucleotide exchange factor activity calcium ion binding intracellular membrane fraction cytoplasm Golgi apparatus cytosol plasma membrane phospholipid metabolic process diacylglycerol biosynthetic process regulation of smooth muscle contraction cytoskeleton organization epidermal growth factor receptor signaling pathway activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway heart development regulation of G-protein coupled receptor protein signaling pathway cell proliferation lipid catabolic process hydrolase activity Ras GTPase binding calcium-mediated signaling calcium-mediated signaling enzyme binding glomerulus development regulation of protein kinase activity regulation of Ras protein signal transduction inositol phosphate-mediated signaling	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system
208485_x_at	-0.505	7.301	-2.721	1.564e-02	0.256	-3.085	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	NM_003879	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
218105_s_at	0.532	7.228	2.721	1.564e-02	0.256	-3.085	MRPL4	mitochondrial ribosomal protein L4	19	10223639, 10223639	NM_015956	51073	19p13.2	Hs.279652	10	structural constituent of ribosome intracellular mitochondrion ribosome translation
229071_at	0.470	4.287	2.721	1.564e-02	0.256	-3.085	C17orf100	chromosome 17 open reading frame 100	17	6495782	AI681419	388327	17p13.1	Hs.262480	2
205072_s_at	-0.491	3.528	-2.720	1.565e-02	0.256	-3.085	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	5	82409072	NM_022406	7518	5q13-q14	Hs.567359	93	condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding nucleus nucleus cytosol DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development protein C-terminus binding response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA repair positive regulation of ligase activity	Non-homologous end-joining
203130_s_at	-0.363	4.474	-2.720	1.565e-02	0.256	-3.085	KIF5C	kinesin family member 5C	2	149349288	NM_004522	3800	2q23.1	Hs.435557 Hs.660699	15	nucleotide binding microtubule motor activity protein binding ATP binding kinesin complex microtubule organelle organization microtubule-based movement
222486_s_at	-1.055	5.462	-2.720	1.567e-02	0.256	-3.087	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	21	-27130476	AF060152	9510	21q21.2	Hs.643357	44	ovulation from ovarian follicle kidney development metalloendopeptidase activity protein binding extracellular region basement membrane proteolysis integrin-mediated signaling pathway heparin binding peptidase activity zinc ion binding negative regulation of cell proliferation cytoplasmic vesicle metal ion binding heart trabecula formation
221645_s_at	0.636	4.360	2.719	1.568e-02	0.257	-3.087	ZNF83	zinc finger protein 83	19	-57807429, -57807429	M27877	55769	19q13.3	Hs.467210 Hs.655934 Hs.659798 Hs.710125	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225939_at	-0.573	6.385	-2.719	1.569e-02	0.257	-3.088	EIF4E3	eukaryotic translation initiation factor 4E family member 3	3	-71811131, -71811131, -71811131, -71811131	AL161983	317649	3p14	Hs.581355	3	RNA binding translation initiation factor activity cytoplasm translational initiation regulation of translation
212934_at	-0.372	6.456	-2.719	1.570e-02	0.257	-3.088	UBXN2B	UBX domain protein 2B	8	59486376	AI245523	137886	8q12.1	Hs.155572	4	nucleus cytoplasm endoplasmic reticulum Golgi apparatus cytosol
225465_at	0.513	7.216	2.719	1.571e-02	0.257	-3.089	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	3	-65319983, -65314945	AK023358	9223	3p14.1	Hs.651939	24	nucleotide binding ATP binding plasma membrane cell-cell junction tight junction protein complex assembly cell adhesion cell surface receptor linked signal transduction protein C-terminus binding	Tight junction
221194_s_at	-0.855	5.781	-2.718	1.572e-02	0.257	-3.090	RNFT1	ring finger protein, transmembrane 1	17	-55384504	NM_016125	51136	17q23.1	Hs.531701	1	protein binding zinc ion binding membrane integral to membrane metal ion binding
1555943_at	0.296	4.872	2.717	1.576e-02	0.257	-3.091	PGAM5	phosphoglycerate mutase family member 5	12	131797508	CA307621	192111	12q24.33	Hs.102558	6	nucleus cytoplasm
202373_s_at	-0.313	8.118	-2.717	1.577e-02	0.258	-3.092	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	AF255648	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
1554129_a_at	0.310	5.428	2.716	1.580e-02	0.258	-3.094	ADIG	adipogenin	20	36643251	BC029594	149685	20q11.23	Hs.368028	3	nucleus cytoplasm membrane integral to membrane positive regulation of fat cell differentiation white fat cell differentiation brown fat cell differentiation
200985_s_at	-0.432	10.405	-2.715	1.581e-02	0.258	-3.094	CD59	CD59 molecule, complement regulatory protein	11	-33681131, -33681131, -33681131	NM_000611	966	11p13	Hs.278573 Hs.709466 Hs.710641	107	protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane	Complement and coagulation cascades Hematopoietic cell lineage
223404_s_at	-0.493	7.473	-2.715	1.581e-02	0.258	-3.095	C1orf25	chromosome 1 open reading frame 25	1	-183353840	AW512122	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
208660_at	0.461	11.140	2.715	1.583e-02	0.258	-3.096	CS	citrate synthase	12	-54951749	BC000105	1431	12q13.2-q13.3	Hs.430606 Hs.715526	20	citrate (Si)-synthase activity citrate (Si)-synthase activity mitochondrion mitochondrial matrix mitochondrial matrix tricarboxylic acid cycle transferase activity cellular carbohydrate metabolic process	Citrate cycle (TCA cycle) Glyoxylate and dicarboxylate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
227551_at	-0.556	7.428	-2.715	1.583e-02	0.258	-3.096	FAM108B1	family with sequence similarity 108, member B1	9	-73669887, -73667187	BE856596	51104	9q21.13	Hs.380389	4	extracellular region hydrolase activity
206409_at	0.235	4.127	2.714	1.584e-02	0.258	-3.096	TIAM1	T-cell lymphoma invasion and metastasis 1	21	-31412606	NM_003253	7074	21q22.1 21q22.11	Hs.517228	49	receptor signaling protein activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding phospholipid binding intracellular plasma membrane small GTPase mediated signal transduction regulation of Rho protein signal transduction ephrin receptor binding ephrin receptor signaling pathway positive regulation of axonogenesis	Chemokine signaling pathway Regulation of actin cytoskeleton
207718_x_at	0.363	4.390	2.714	1.585e-02	0.258	-3.097	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	19	-46073183	NM_000764	1549	19q13.2	Hs.250615	13	endoplasmic reticulum microsome electron carrier activity membrane oxygen binding heme binding metal ion binding oxidation reduction aromatase activity	Caffeine metabolism Retinol metabolism Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
200093_s_at	-0.346	10.848	-2.713	1.587e-02	0.258	-3.098	HINT1	histidine triad nucleotide binding protein 1	5	-130522773, -130522773	N32864	3094	5q31.2	Hs.483305	26	protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity
241009_at	0.411	4.310	2.713	1.588e-02	0.258	-3.098	FOXN4	forkhead box N4	12	-108200165	AI243313	121643	12q24.11	Hs.528316	6	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
201067_at	-0.535	8.272	-2.712	1.590e-02	0.259	-3.100	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	7	102775324	BF215487	5701	7q22.1-q22.3	Hs.437366	56	nucleotide binding proteasome complex protein binding ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
231982_at	0.298	5.089	2.712	1.591e-02	0.259	-3.100	LOC284422	similar to HSPC323	19	-3425404	AF161441	284422	19p13.3	Hs.130714 Hs.718889	2	membrane integral to membrane
207910_at	0.328	3.144	2.712	1.592e-02	0.259	-3.101	SCGB1D1	secretoglobin, family 1D, member 1	11	61714285	NM_006552	10648	11q13	Hs.202686	4	binding extracellular region extracellular space
1564658_at	0.311	6.940	2.712	1.592e-02	0.259	-3.101	C7orf52	chromosome 7 open reading frame 52	7	-100600497	BC037583	375607	7q22.1	Hs.213044	2	N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
204950_at	0.473	6.268	2.712	1.593e-02	0.259	-3.101	CARD8	caspase recruitment domain family, member 8	19	-53403154	NM_014959	22900	19q13.33	Hs.446146 Hs.655940	23	protein binding intracellular nucleus cytoplasm caspase activator activity NACHT domain binding protein homodimerization activity regulation of apoptosis negative regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of caspase activity positive regulation of interleukin-1 beta secretion
219546_at	-0.330	3.642	-2.712	1.593e-02	0.259	-3.101	BMP2K	BMP2 inducible kinase	4	79916555, 79916555	NM_017593	55589	4q21.21	Hs.146551	11	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity
1561048_at	-0.291	4.920	-2.711	1.593e-02	0.259	-3.102	RARS2	arginyl-tRNA synthetase 2, mitochondrial	6	-88280815	AF143874	57038	6q16.1	Hs.485910	8	nucleotide binding arginine-tRNA ligase activity protein binding ATP binding cytoplasm mitochondrion mitochondrial matrix arginyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
202590_s_at	0.433	8.502	2.711	1.594e-02	0.259	-3.102	PDK2	pyruvate dehydrogenase kinase, isozyme 2	17	45527694	AL574319	5164	17q21.33	Hs.256667	28	two-component sensor activity nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity protein binding ATP binding nucleus nucleolus mitochondrion mitochondrial matrix carbohydrate metabolic process glucose metabolic process signal transduction transferase activity peptidyl-histidine phosphorylation
1552880_at	0.327	2.885	2.711	1.594e-02	0.259	-3.102	SEC16B	SEC16 homolog B (S. cerevisiae)	1	-176164864	NM_033127	89866	1q25.2	Hs.709633	10	endoplasmic reticulum Golgi apparatus protein transport membrane vesicle-mediated transport
202770_s_at	-0.919	4.848	-2.711	1.595e-02	0.259	-3.102	CCNG2	cyclin G2	4	78297380	NM_004354	901	4q21.1	Hs.13291	12	cell cycle checkpoint cytoplasm cell cycle mitosis cell division	p53 signaling pathway
213286_at	-0.536	5.192	-2.711	1.595e-02	0.259	-3.102	ZFR	zinc finger RNA binding protein	5	-32390212	BF445199	51663	5p13.3	Hs.435231	6	DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding
213688_at	-0.362	4.880	-2.710	1.596e-02	0.259	-3.103	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	N25325	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
221073_s_at	0.305	6.206	2.710	1.599e-02	0.259	-3.104	NOD1	nucleotide-binding oligomerization domain containing 1	7	-30430667	NM_006092	10392	7p15-p14	Hs.405153	72	nucleotide binding ATP binding intracellular cytoplasm induction of apoptosis activation of caspase activity inflammatory response intracellular signaling cascade caspase activator activity detection of bacterium positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade interleukin-8 biosynthetic process identical protein binding peptidoglycan binding regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JNK cascade CARD domain binding defense response to Gram-positive bacterium protein oligomerization positive regulation of ERK1 and ERK2 cascade	Epithelial cell signaling in Helicobacter pylori infection
225806_at	0.552	3.152	2.710	1.599e-02	0.259	-3.105	JUB	jub, ajuba homolog (Xenopus laevis)	14	-22510249, -22510249	AI289311	84962	14q11.2	Hs.655832	16	protein binding nucleus cytoplasm centrosome cytoskeleton plasma membrane focal adhesion cell cycle cell adhesion zinc ion binding lamellipodium lamellipodium assembly cell junction regulation of cell migration wound healing, spreading of epidermal cells regulation of GTPase activity metal ion binding focal adhesion formation
213036_x_at	0.294	6.100	2.709	1.600e-02	0.259	-3.105	ATP2A3	ATPase, Ca++ transporting, ubiquitous	17	-3773917	Y15724	489	17p13.3	Hs.513870	27	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding protein binding ATP binding nucleus ATP biosynthetic process cation transport calcium ion transport metabolic process membrane integral to membrane sarcoplasmic reticulum hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway Alzheimer's disease
239261_s_at	0.305	4.830	2.709	1.601e-02	0.259	-3.106	CORIN	corin, serine peptidase	4	-47290774	AI338960	10699	4p13-p12	Hs.518618	15	serine-type endopeptidase activity scavenger receptor activity plasma membrane integral to plasma membrane proteolysis lipid metabolic process regulation of blood pressure peptidase activity anatomical structure morphogenesis cell surface
226370_at	-0.702	5.697	-2.709	1.602e-02	0.259	-3.107	KLHL15	kelch-like 15 (Drosophila)	X	-23911756	BG149487	80311	Xp22.1-p21	Hs.495854	6	protein binding modification-dependent protein catabolic process
1560553_at	0.274	4.666	2.709	1.603e-02	0.259	-3.107	TIAF1	TGFB1-induced anti-apoptotic factor 1	17	-24424664	BC011938	9220	17q11.2	Hs.462590	15	molecular_function nucleus apoptosis anti-apoptosis I-kappaB kinase/NF-kappaB cascade
228039_at	-0.491	7.700	-2.708	1.603e-02	0.259	-3.107	DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	5	134122359	AI765169	9879	5q31.1	Hs.406549	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing Cajal body nuclear speck hydrolase activity
202598_at	-0.841	8.934	-2.708	1.605e-02	0.259	-3.108	S100A13	S100 calcium binding protein A13	1	-151857899, -151857899, -151857899, -151857899, -151857899	NM_005979	6284	1q21	Hs.516505	24	calcium ion binding cellular_component cell differentiation
233584_at	0.362	3.745	2.707	1.608e-02	0.260	-3.110	C20orf62	chromosome 20 open reading frame 62	20		AI138237	140834	20q13.12	Hs.357589	3
210203_at	-0.729	5.704	-2.706	1.610e-02	0.260	-3.111	CNOT4	CCR4-NOT transcription complex, subunit 4	7	-134723303, -134697088	R64001	4850	7q22-qter	Hs.490224	7	nucleotide binding RNA binding protein binding nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process regulation of transcription metal ion binding	RNA degradation
218100_s_at	-0.385	6.152	-2.705	1.613e-02	0.260	-3.112	IFT57	intraflagellar transport 57 homolog (Chlamydomonas)	3	-109362348	NM_018010	55081	3q13.12-q13.13	Hs.412196	13	DNA binding protein binding Golgi apparatus cilium microtubule basal body activation of caspase activity regulation of apoptosis regulation of transcription	Huntington's disease
1558143_a_at	0.340	4.555	2.705	1.613e-02	0.260	-3.113	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2	111594961, 111594961	AK027160	10018	2q13	Hs.469658	143	peripheral to membrane of membrane fraction in utero embryonic development B cell homeostasis B cell apoptosis kidney development myeloid cell homeostasis protein binding cytoplasm mitochondrion mitochondrial outer membrane cytosol plasma membrane induction of apoptosis cell-matrix adhesion spermatogenesis microtubule binding male gonad development activation of pro-apoptotic gene products post-embryonic development mammary gland development tube lumen formation odontogenesis of dentine-containing tooth T cell homeostasis ear development regulation of organ growth regulation of pigmentation during development spleen development thymus development post-embryonic organ morphogenesis
208750_s_at	-0.749	8.765	-2.705	1.614e-02	0.260	-3.113	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AA580004	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
205168_at	0.294	4.954	2.705	1.615e-02	0.260	-3.113	DDR2	discoidin domain receptor tyrosine kinase 2	1	160868851	NM_006182	4921	1q23.3	Hs.275757 Hs.593833	26	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation cell adhesion signal transduction transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell proliferation membrane transferase activity
208913_at	-0.487	7.188	-2.705	1.615e-02	0.260	-3.114	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	16	-23383143	AA868560	23062	16p12	Hs.460336	37	protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding	Lysosome
225087_at	-0.626	8.708	-2.705	1.615e-02	0.260	-3.114	C16orf63	chromosome 16 open reading frame 63	16	-15867077	AA524072	123811	16p13.11	Hs.514179	3
1556919_at	0.348	4.185	2.705	1.615e-02	0.260	-3.114	LEPR	leptin receptor	1	65658905, 65658905, 65658905	BC035120	3953	1p31	Hs.705413	260	angiogenesis ovulation from ovarian follicle cytokine receptor activity protein binding extracellular region extracellular space plasma membrane energy reserve metabolic process cell surface receptor linked signal transduction multicellular organismal development female pregnancy cholesterol metabolic process integral to membrane protein-hormone receptor activity peptide hormone binding cellular response to nutrient levels response to nicotine response to chemical stimulus eating behavior response to estrogen stimulus negative regulation of hydrolase activity	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Jak-STAT signaling pathway Adipocytokine signaling pathway
1553391_at	0.367	2.680	2.704	1.616e-02	0.260	-3.114	CXorf58	chromosome X open reading frame 58	X	23836043	NM_152761	254158	Xp22.11	Hs.351265	4
204171_at	-0.390	5.842	-2.704	1.616e-02	0.260	-3.114	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	NM_003161	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
225333_at	0.317	4.335	2.704	1.616e-02	0.260	-3.114	ZNF496	zinc finger protein 496	1	-245530244	AI218383	84838	1q44	Hs.654803	5	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1557895_at	0.290	2.324	2.703	1.620e-02	0.260	-3.116	FLJ35934	FLJ35934 protein	17		BC033201	400579	17p11.2	Hs.375092	2
212460_at	-0.463	6.872	-2.703	1.620e-02	0.260	-3.116	C14orf147	chromosome 14 open reading frame 147	14	-33971894	BE738425	171546	14q13.1	Hs.269909	5	serine C-palmitoyltransferase activity protein binding endoplasmic reticulum membrane integral to membrane serine C-palmitoyltransferase complex sphingolipid biosynthetic process
1560274_at	-0.355	2.481	-2.703	1.622e-02	0.261	-3.117	WTAP	Wilms tumor 1 associated protein	6	160068141, 160068141, 160068609	BF679507	9589	6q25-q27	Hs.446091 Hs.710715	16	nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane
216342_x_at	0.370	11.005	2.702	1.623e-02	0.261	-3.118	RPS4X	ribosomal protein S4, X-linked	X	-71409177	AL121916	6191	Xq13.1	Hs.118076	25	structural constituent of ribosome intracellular cytosol ribosome polysome translational elongation multicellular organismal development positive regulation of cell proliferation rRNA binding cytosolic small ribosomal subunit cytosolic small ribosomal subunit positive regulation of translation	Ribosome
229121_at	0.288	5.331	2.702	1.625e-02	0.261	-3.119	CMKLR1	chemokine-like receptor 1	12	-107205951, -107205951	BE857553	1240	12q24.1	Hs.197143	14	skeletal system development receptor activity G-protein coupled receptor activity chemokine receptor activity plasma membrane integral to plasma membrane chemotaxis immune response signal transduction G-protein coupled receptor protein signaling pathway
208641_s_at	-0.340	9.819	-2.701	1.627e-02	0.261	-3.120	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	BC004247	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
217868_s_at	-0.287	8.863	-2.700	1.629e-02	0.261	-3.122	METTL9	methyltransferase like 9	16	21518356	NM_016025	51108	16p13-p12	Hs.279583	6
218844_at	0.423	7.076	2.700	1.630e-02	0.261	-3.122	ACSF2	acyl-CoA synthetase family member 2	17	45858517	NM_025149	80221	17q21.33	Hs.288959	7	nucleotide binding ATP binding mitochondrion lipid metabolic process fatty acid metabolic process metabolic process ligase activity
219828_at	0.279	5.830	2.699	1.632e-02	0.262	-3.123	C9orf86	chromosome 9 open reading frame 86	9	138822201	NM_024718	55684	9q34.3	Hs.370555	11	nucleotide binding protein binding GTP binding nucleus cytoplasm small GTPase mediated signal transduction
213499_at	0.317	5.155	2.699	1.633e-02	0.262	-3.124	CLCN2	chloride channel 2	3	-185547033	NM_004366	1181	3q27-q28	Hs.436847	28	voltage-gated ion channel activity voltage-gated chloride channel activity ion transport chloride transport membrane integral to membrane chloride ion binding chloride channel complex
224534_at	-0.698	3.620	-2.699	1.634e-02	0.262	-3.124	KREMEN1	kringle containing transmembrane protein 1	22	27799065, 27799105	AB059618	83999	22q12.1	Hs.229335	11	molecular_function membrane fraction cell communication membrane integral to membrane Wnt receptor signaling pathway
229849_at	-0.669	8.410	-2.699	1.634e-02	0.262	-3.124	WIPF3	WAS/WASL interacting protein family, member 3	7	29840865	AI807950	644150	7p14.3	Hs.709280	5	actin binding cytoplasm multicellular organismal development spermatogenesis cell differentiation
242268_at	-0.510	3.571	-2.699	1.635e-02	0.262	-3.125	CUGBP2	CUG triplet repeat, RNA binding protein 2	10	11087264, 11099898, 11246998	BE157991	10659	10p13	Hs.309288	25	nucleotide binding RNA binding protein binding nucleus cytoplasm mRNA processing regulation of heart contraction
235389_at	-0.438	6.704	-2.698	1.635e-02	0.262	-3.125	PHF20	PHD finger protein 20	20	33823336	BG168139	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
242844_at	-0.431	5.604	-2.698	1.636e-02	0.262	-3.125	PGGT1B	protein geranylgeranyltransferase type I, beta subunit	5	-114574425	AA989220	5229	5q22.3	Hs.254006	8	prenyltransferase activity CAAX-protein geranylgeranyltransferase activity CAAX-protein geranylgeranyltransferase complex zinc ion binding transferase activity protein amino acid geranylgeranylation metal ion binding
200713_s_at	-0.387	7.879	-2.698	1.636e-02	0.262	-3.126	MAPRE1	microtubule-associated protein, RP/EB family, member 1	20	30871359	NM_012325	22919	20q11.1-q11.23	Hs.472437	31	cytoplasm Golgi apparatus spindle cytoplasmic microtubule cell cycle mitosis protein C-terminus binding cell proliferation cortical microtubule cytoskeleton negative regulation of microtubule polymerization cell projection membrane cell projection microtubule plus-end binding cell division
226058_at	0.361	5.513	2.698	1.637e-02	0.262	-3.126	B3GNT9	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	16	-65739505	AI651445	84752	16q22.1	Hs.718517	2	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups
200896_x_at	-0.335	9.699	-2.698	1.638e-02	0.262	-3.126	HDGF	hepatoma-derived growth factor (high-mobility group protein 1-like)	1	-154978522, -154978522, -154978522	NM_004494	3068	1q21-q23	Hs.506748	22	nucleotide binding DNA binding extracellular space nucleus cytoplasm signal transduction growth factor activity heparin binding cell proliferation regulation of transcription
203622_s_at	-0.562	7.314	-2.698	1.639e-02	0.262	-3.127	PNO1	partner of NOB1 homolog (S. cerevisiae)	2	68238508	NM_020143	56902	2p14	Hs.262858	8	RNA binding nucleus nucleolus
230367_at	-1.853	9.957	-2.697	1.639e-02	0.262	-3.127	SMTNL1	smoothelin-like 1	11	57065554	AI359511	219537	11q12.1	Hs.68756	2	response to activity peptidyl-serine phosphorylation M band I band response to drug contractile fiber positive regulation of vasoconstriction negative regulation of vasodilation muscle organ morphogenesis
1561093_at	0.312	6.479	2.697	1.640e-02	0.262	-3.127	SLC22A25	solute carrier family 22, member 25	11	-62687871	AK091990	387601	11q12.3	Hs.332119	5	transport membrane integral to membrane
209100_at	-0.618	8.381	-2.697	1.640e-02	0.262	-3.128	IFRD2	interferon-related developmental regulator 2	3	-50300168	BC001327	7866	3p21.3	Hs.315177 Hs.719200	7	binding cellular_component cell proliferation cell differentiation
205113_at	-0.556	2.959	-2.697	1.641e-02	0.262	-3.128	NEFM	neurofilament, medium polypeptide	8	24827178, 24828359	NM_005382	4741	8p21	Hs.458657 Hs.615287	24	microtubule cytoskeleton organization structural constituent of cytoskeleton cytoskeleton neurofilament axon cargo transport axon regulation of axon diameter neuromuscular junction intermediate filament bundle assembly neurofilament cytoskeleton organization	Amyotrophic lateral sclerosis (ALS)
231849_at	-0.766	3.849	-2.697	1.642e-02	0.262	-3.128	KRT80	keratin 80	12	-50849046	AL162069	144501	12q13.13	Hs.140978	3	structural molecule activity keratin filament
219365_s_at	0.359	5.565	2.696	1.642e-02	0.262	-3.129	CAMKV	CaM kinase-like vesicle-associated	3	-49870425	NM_024046	79012	3p21.31	Hs.145156	10	protein serine/threonine kinase activity ATP binding plasma membrane protein amino acid phosphorylation cytoplasmic vesicle
223803_s_at	-0.584	6.483	-2.695	1.647e-02	0.262	-3.131	ZCCHC10	zinc finger, CCHC domain containing 10	5	-132360575	BC005211	54819	5q31.1	Hs.29700	5	nucleic acid binding zinc ion binding metal ion binding
214705_at	-0.999	4.385	-2.695	1.647e-02	0.262	-3.131	INADL	InaD-like (Drosophila)	1	61980736	AJ001306	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
203787_at	-0.560	7.330	-2.695	1.648e-02	0.262	-3.132	SSBP2	single-stranded DNA binding protein 2	5	-80751427	NM_012446	23635	5q14.1	Hs.102735	14	DNA binding single-stranded DNA binding protein binding nucleus cytoplasm transcription regulator activity regulation of transcription
210349_at	0.316	3.436	2.694	1.650e-02	0.262	-3.133	CAMK4	calcium/calmodulin-dependent protein kinase IV	5	110587980	L24959	814	5q21.3	Hs.591269	46	nucleotide binding calmodulin-dependent protein kinase activity calcium ion binding calmodulin binding ATP binding nucleus nucleolus cytoplasm protein amino acid phosphorylation signal transduction transferase activity	Calcium signaling pathway Long-term potentiation Neurotrophin signaling pathway
213793_s_at	-0.790	8.633	-2.694	1.650e-02	0.262	-3.133	HOMER1	homer homolog 1 (Drosophila)	5	-78705541	BE550452	9456	5q14.2	Hs.591761	33	skeletal muscle contraction protein binding membrane fraction cytoplasm plasma membrane integral to plasma membrane activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway synaptic transmission postsynaptic density Z disc cell junction positive regulation of calcium ion transport via store-operated calcium channel activity costamere synapse postsynaptic membrane skeletal muscle fiber development
234685_x_at	0.344	3.300	2.694	1.651e-02	0.262	-3.133	KRTAP4-9	keratin associated protein 4-9	17	36515166	AJ406941	100132386	17q21.2	Hs.307018 Hs.711926	1	keratin filament
209138_x_at	0.750	4.901	2.694	1.651e-02	0.263	-3.134	IGL@	immunoglobulin lambda locus	22		M87790	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
227430_at	-0.300	5.288	-2.693	1.653e-02	0.263	-3.135	ZC3H10	zinc finger CCCH-type containing 10	12	54798296	AI969773	84872	12q13.2	Hs.632706	7	nucleic acid binding zinc ion binding metal ion binding
240479_at	0.411	5.098	2.693	1.654e-02	0.263	-3.135	HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	6	-114483442	AW449310	222537	6q21	Hs.645477	8	protein binding Golgi apparatus protein amino acid sulfation sulfotransferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane integral to membrane transferase activity regulation of virion penetration into host cell 3'-phosphoadenosine 5'-phosphosulfate binding negative regulation of coagulation	Heparan sulfate biosynthesis
214183_s_at	0.772	4.083	2.693	1.654e-02	0.263	-3.135	TKTL1	transketolase-like 1	X	153177220, 153186602	X91817	8277	Xq28	Hs.102866	21	transketolase activity calcium ion binding nucleus cytoplasm glucose catabolic process thiamin metabolic process metabolic process transferase activity	Pentose phosphate pathway Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of plant hormones Metabolic pathways
217367_s_at	-0.317	5.554	-2.693	1.654e-02	0.263	-3.135	ZHX3	zinc fingers and homeoboxes 3	20	-39240502	AB007855	23051	20q12	Hs.380133	13	transcription factor activity protein binding intracellular nucleus cytoplasm zinc ion binding sequence-specific DNA binding negative regulation of transcription, DNA-dependent metal ion binding
208800_at	-0.481	6.344	-2.693	1.654e-02	0.263	-3.135	SRP72	signal recognition particle 72kDa	4	57028518	AV702627	6731	4q11	Hs.237825	18	signal recognition particle binding binding cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane 7S RNA binding response to drug	Protein export
209955_s_at	-0.517	5.768	-2.692	1.656e-02	0.263	-3.136	FAP	fibroblast activation protein, alpha	2	-162735445	U76833	2191	2q23	Hs.654370	34	metalloendopeptidase activity serine-type endopeptidase activity plasma membrane proteolysis peptidase activity dipeptidyl-peptidase activity integral to membrane lamellipodium protein homodimerization activity
242979_at	0.769	5.326	2.692	1.658e-02	0.263	-3.137	IRS1	insulin receptor substrate 1	2	-227304276	AI474666	3667	2q36	Hs.471508	290	positive regulation of mesenchymal cell proliferation signal transducer activity transmembrane receptor protein tyrosine kinase docking protein activity protein kinase C binding insulin receptor binding insulin-like growth factor receptor binding protein binding nucleus cytoplasm microsome plasma membrane insulin receptor complex caveola signal transduction positive regulation of glucose metabolic process phosphoinositide 3-kinase cascade positive regulation of cell migration mammary gland development positive regulation of fatty acid beta-oxidation SH2 domain binding glucose homeostasis response to peptide hormone stimulus protein kinase B signaling cascade phosphoinositide 3-kinase binding phosphoinositide 3-kinase binding positive regulation of phosphoinositide 3-kinase activity positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of glucose import negative regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway	Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus
1558688_at	0.367	8.913	2.691	1.659e-02	0.263	-3.138	LOC441461	hypothetical LOC441461	9		BG701300	441461	9q31.1	Hs.163155	1
218772_x_at	-0.847	8.424	-2.691	1.660e-02	0.263	-3.138	TMEM38B	transmembrane protein 38B	9	107496645	NM_018112	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
1554127_s_at	-0.689	8.134	-2.691	1.660e-02	0.263	-3.138	MSRB3	methionine sulfoxide reductase B3	12	63958754	BC040053	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
203556_at	-0.472	7.461	-2.690	1.663e-02	0.263	-3.140	ZHX2	zinc fingers and homeoboxes 2	8	123863081	NM_014943	22882	8q24.13	Hs.658443 Hs.719079	12	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding intracellular nucleus mRNA catabolic process zinc ion binding sequence-specific DNA binding metal ion binding
203911_at	0.259	7.006	2.690	1.665e-02	0.263	-3.141	RAP1GAP	RAP1 GTPase activating protein	1	-21795295, -21795295	NM_002885	5909	1p36.1-p35	Hs.148178	40	GTPase activator activity intracellular Golgi apparatus signal transduction membrane regulation of small GTPase mediated signal transduction
209568_s_at	0.514	6.717	2.689	1.666e-02	0.263	-3.142	RGL1	ral guanine nucleotide dissociation stimulator-like 1	1	181871830	AF186779	23179	1q25.3	Hs.497148	6	guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular signal transduction Ral guanyl-nucleotide exchange factor activity regulation of small GTPase mediated signal transduction
1554894_a_at	0.340	7.366	2.689	1.666e-02	0.263	-3.142	PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	5	134268708	AF499009	84105	5q31.1	Hs.710014	11	phenylalanine 4-monooxygenase activity protein binding cellular_component nucleus tetrahydrobiopterin biosynthetic process 4-alpha-hydroxytetrahydrobiopterin dehydratase activity lyase activity positive regulation of transcription, DNA-dependent protein homotetramerization protein heterooligomerization
221547_at	-0.441	7.682	-2.689	1.666e-02	0.263	-3.142	PRPF18	PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae)	10	13668944	BC000794	8559	10p13	Hs.161181	6	nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck
241280_at	0.291	4.639	2.689	1.668e-02	0.264	-3.143	ALDOB	aldolase B, fructose-bisphosphate	9	-103222662	AV650426	229	9q21.3-q22.2	Hs.530274	40	fructose-bisphosphate aldolase activity microtubule organizing center glycolysis NADH oxidation cytoskeletal protein binding metabolic process lyase activity fructose 1,6-bisphosphate metabolic process positive regulation of ATPase activity centriolar satellite identical protein binding ATPase binding fructose binding vacuolar proton-transporting V-type ATPase complex assembly	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
226653_at	-0.437	4.608	-2.688	1.669e-02	0.264	-3.143	MARK1	MAP/microtubule affinity-regulating kinase 1	1	218768190	AB040910	4139	1q41	Hs.497806	27	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm protein amino acid phosphorylation cytoskeleton organization protein kinase cascade microtubule cytoskeleton transferase activity
226673_at	0.464	5.653	2.688	1.670e-02	0.264	-3.143	SH2D3C	SH2 domain containing 3C	9	-129540416, -129540416, -129540416, -129540416, -129540416, -129540416	AW665063	10044	9q34.11	Hs.306412	16	SH3/SH2 adaptor activity guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm JNK cascade small GTPase mediated signal transduction membrane
225215_s_at	-0.394	8.333	-2.688	1.670e-02	0.264	-3.144	MTRF1L	mitochondrial translational release factor 1-like	6	-153350092	BF665339	54516	6q25-q26	Hs.225836 Hs.304818	9	cytoplasm mitochondrion translational termination translation release factor activity, codon specific
210149_s_at	0.315	11.939	2.688	1.671e-02	0.264	-3.144	ATP5H	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d	17	-70546549	AF061735	10476	17q25	Hs.514465	13	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1559507_at	0.318	3.567	2.688	1.672e-02	0.264	-3.145	LOC100130357	similar to hCG2038897	6		AK091836	100130357	6p24.1	Hs.657498	1
228408_s_at	-0.539	7.590	-2.687	1.673e-02	0.264	-3.145	SDAD1	SDA1 domain containing 1	4	-77090091	AI738666	55153	4q21.1	Hs.632604	9	protein binding nucleus nucleolus protein transport ribosome biogenesis
231837_at	-0.668	7.163	-2.687	1.673e-02	0.264	-3.145	USP28	ubiquitin specific peptidase 28	11	-113173806	AB040948	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
219623_at	-0.260	6.189	-2.687	1.674e-02	0.264	-3.146	ACTR5	ARP5 actin-related protein 5 homolog (yeast)	20	36810510	NM_024855	79913	20q11.23	Hs.371585	7	protein binding ATP binding regulation of transcription
212482_at	-0.693	8.151	-2.687	1.675e-02	0.264	-3.146	RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	2	86800924	BF671894	64795	2p11.2	Hs.75277	7
219067_s_at	-0.308	6.848	-2.687	1.675e-02	0.264	-3.147	NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	10	-123706592	NM_017615	54780	10q26.13	Hs.258798	8
225106_s_at	-0.531	7.059	-2.686	1.676e-02	0.264	-3.147	OGFOD1	2-oxoglutarate and iron-dependent oxygenase domain containing 1	16	55042924	AK022130	55239	16q12.2	Hs.231883	4	iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors L-ascorbic acid binding metal ion binding oxidation reduction
237247_at	0.400	2.893	2.686	1.679e-02	0.264	-3.148	USP51	ubiquitin specific peptidase 51	X	-55529686	AI341140	158880	Xp11.21	Hs.134289	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding
228438_at	0.728	3.703	2.685	1.681e-02	0.264	-3.150	LOC100132891	hypothetical protein LOC100132891	8		AI948599	100132891	8q13.3	Hs.137674
244103_at	-0.385	8.033	-2.684	1.685e-02	0.265	-3.152	C1orf55	chromosome 1 open reading frame 55	1	-224237025	AW963092	163859	1q42.12	Hs.520192	2
1552757_s_at	0.341	3.331	2.684	1.685e-02	0.265	-3.152	C9orf66	chromosome 9 open reading frame 66	9	-203107	AI478419	157983	9p24.3	Hs.190877	3
209398_at	-0.651	8.565	-2.684	1.685e-02	0.265	-3.152	HIST1H1C	histone cluster 1, H1c	6	-26163946	BC002649	3006	6p21.3	Hs.7644	17	nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly nucleosome positioning
205849_s_at	0.248	12.106	2.683	1.686e-02	0.265	-3.152	UQCRB	ubiquinol-cytochrome c reductase binding protein	8	-97308479	NM_006294	7381	8q22	Hs.131255	10	mitochondrion mitochondrial respiratory chain oxidative phosphorylation mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity aerobic respiration membrane electron transport chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
214081_at	-0.629	5.945	-2.683	1.687e-02	0.265	-3.153	PLXDC1	plexin domain containing 1	17	-34473082	AF070526	57125	17q21.1	Hs.125036	11	angiogenesis molecular_function extracellular region cytoplasm membrane integral to membrane
220035_at	0.420	4.987	2.683	1.687e-02	0.265	-3.153	NUP210	nucleoporin 210kDa	3	-13332736	NM_024923	23225	3p25.1	Hs.475525	24	protein binding nucleus nuclear pore endoplasmic reticulum protein transport membrane integral to membrane mRNA transport intracellular protein transmembrane transport
203756_at	0.309	6.736	2.683	1.687e-02	0.265	-3.153	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	11	72697310	NM_014786	9828	11q13.4	Hs.533719 Hs.719521	8	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular actin cytoskeleton organization regulation of Rho protein signal transduction
229052_at	-0.481	11.505	-2.683	1.688e-02	0.265	-3.153	ANKRD23	ankyrin repeat domain 23	2	-96867377	AI637712	200539	2q11.2	Hs.643430	8	nucleus
218552_at	0.443	8.683	2.683	1.689e-02	0.265	-3.154	ECHDC2	enoyl Coenzyme A hydratase domain containing 2	1	-53134491	NM_018281	55268	1p32.3	Hs.476319	2	mitochondrion lipid metabolic process fatty acid metabolic process metabolic process lyase activity
212311_at	0.404	4.444	2.683	1.689e-02	0.265	-3.154	KIAA0746	KIAA0746 protein	4	-25358146	AA522514	23231	4p15.2	Hs.479384	5	binding membrane integral to membrane
207364_at	0.367	5.050	2.682	1.689e-02	0.265	-3.154	TEX28	testis expressed 28	X	-153152125	NM_001586	1527	Xq28	Hs.672606	7	molecular_function biological_process membrane integral to membrane
208583_x_at	-0.253	6.372	-2.682	1.690e-02	0.265	-3.154	HIST1H2AJ	histone cluster 1, H2aj	6	-27890058	NM_021066	8331	6p22-p21.3	Hs.406691	10		Systemic lupus erythematosus
226895_at	-0.489	10.055	-2.682	1.691e-02	0.265	-3.155	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	19	3310615, 3317572	AW134798	4782	19p13.3	Hs.170131	23	negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus DNA replication regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter
213564_x_at	0.969	11.752	2.681	1.694e-02	0.265	-3.156	LDHB	lactate dehydrogenase B	12	-21679542	BE042354	3945	12p12.2-p12.1	Hs.446149	27	L-lactate dehydrogenase activity binding cytoplasm oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
223310_x_at	-0.387	8.806	-2.681	1.695e-02	0.265	-3.157	PNPLA8	patatin-like phospholipase domain containing 8	7	-107899306	AF217519	50640	7q31	Hs.617340	13	lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm
222731_at	-0.612	8.411	-2.681	1.696e-02	0.265	-3.157	ZDHHC2	zinc finger, DHHC-type containing 2	8	17058206	AK001608	51201	8p21.3-p22	Hs.443852	8	zinc ion binding membrane integral to membrane palmitoyltransferase activity transferase activity protein palmitoylation metal ion binding
225414_at	-0.369	7.334	-2.680	1.696e-02	0.265	-3.158	RNF149	ring finger protein 149	2	-101258984	AL558987	284996	2q11.2	Hs.142074	8	protein binding zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
224905_at	-0.447	6.667	-2.680	1.698e-02	0.266	-3.159	WDR26	WD repeat domain 26	1	-222639467	AA482548	80232	1q42.11-q42.12	Hs.497873	8	cytoplasm
232004_at	-0.451	6.054	-2.679	1.701e-02	0.266	-3.160	HNRNPR	heterogeneous nuclear ribonucleoprotein R	1	-23508862	AK001846	10236	1p36.12	Hs.373763	17	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex RNA splicing heterogeneous nuclear ribonucleoprotein complex
213575_at	0.487	5.007	2.679	1.702e-02	0.266	-3.161	TRA2A	transformer 2 alpha homolog (Drosophila)	7	-23510925	AA831170	29896	7p15.3	Hs.445652	11	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding nucleus RNA splicing identical protein binding
212236_x_at	0.304	6.113	2.678	1.703e-02	0.266	-3.161	KRT17	keratin 17	17	-37029217	Z19574	3872	17q12-q21	Hs.2785	39	structural constituent of cytoskeleton protein binding nucleus nucleolus cytoplasm cytoskeleton intermediate filament epidermis development
219088_s_at	-0.315	5.828	-2.678	1.704e-02	0.266	-3.162	ZNF576	zinc finger protein 576	19	48792383, 48792577	AA639585	79177	19q13.31	Hs.11110	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212657_s_at	0.339	4.343	2.677	1.707e-02	0.266	-3.163	IL1RN	interleukin 1 receptor antagonist	2	113591940, 113601608	U65590	3557	2q14.2	Hs.81134	610	cytokine activity interleukin-1 receptor antagonist activity protein binding extracellular region extracellular space intracellular cytoplasm inflammatory response immune response response to glucocorticoid stimulus
219415_at	0.277	3.980	2.677	1.707e-02	0.266	-3.163	TTYH1	tweety homolog 1 (Drosophila)	19	59618446	NM_020659	57348	19q13.4	Hs.268728	4	ion channel activity chloride channel activity iron ion transmembrane transporter activity protein binding plasma membrane ion transport iron ion transport cell adhesion integral to membrane chloride ion binding chloride channel complex
205730_s_at	0.636	6.986	2.677	1.708e-02	0.266	-3.164	ABLIM3	actin binding LIM protein family, member 3	5	148501246	NM_014945	22885	5q32	Hs.49688	15	actin binding cytoplasm cytoskeleton organization zinc ion binding positive regulation of transcription from RNA polymerase II promoter metal ion binding	Axon guidance
238207_at	0.288	5.556	2.677	1.709e-02	0.266	-3.164	LOC440957	similar to CG32736-PA	3	52545660	AW003138	440957	3p21.1	Hs.660577	3	membrane integral to membrane
213044_at	-0.343	7.475	-2.677	1.709e-02	0.266	-3.165	ROCK1	Rho-associated, coiled-coil containing protein kinase 1	18	-16783700	N22548	6093	18q11.1	Hs.306307	134	nucleotide binding cytokinesis protein serine/threonine kinase activity ATP binding intracellular cytoplasm Golgi apparatus centriole cytosol protein amino acid phosphorylation apoptosis intracellular signaling cascade Rho protein signal transduction zinc ion binding membrane transferase activity diacylglycerol binding membrane to membrane docking actin cytoskeleton organization bleb formation identical protein binding negative regulation of neuron apoptosis metal ion binding leukocyte migration leukocyte tethering or rolling	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
218651_s_at	1.079	6.598	2.677	1.709e-02	0.266	-3.165	LARP6	La ribonucleoprotein domain family, member 6	15	-68930821, -68910942	NM_018357	55323	15q23	Hs.416755	5	RNA binding nucleus cytoplasm RNA processing ribonucleoprotein complex
200611_s_at	-0.484	7.686	-2.676	1.710e-02	0.266	-3.165	WDR1	WD repeat domain 1	4	-9685060	AB010427	9948	4p16.1	Hs.128548 Hs.713658	15	actin binding protein binding cytoplasm cytoskeleton sensory perception of sound
226679_at	0.422	6.465	2.676	1.710e-02	0.266	-3.165	SLC26A11	solute carrier family 26, member 11	17	75808831	BE964598	284129	17q25.3	Hs.4866	4	transporter activity endoplasmic reticulum Golgi apparatus plasma membrane ion transport secondary active sulfate transmembrane transporter activity sulfate transport anion transmembrane transporter activity anion exchanger activity integral to membrane
225040_s_at	-0.433	5.657	-2.676	1.710e-02	0.266	-3.165	RPE	ribulose-5-phosphate-3-epimerase	2	210575596, 210575625	AV699857	6120	2q32-q33.3	Hs.282260	11	ribulose-phosphate 3-epimerase activity ribulose-phosphate 3-epimerase activity protein binding cytosol carbohydrate metabolic process metabolic process isomerase activity	Pentose phosphate pathway Pentose and glucuronate interconversions Carbon fixation in photosynthetic organisms Metabolic pathways
1558700_s_at	0.641	4.153	2.676	1.711e-02	0.266	-3.166	ZNF260	zinc finger protein 260	19	-41693433	BC042676	339324	19q13.12	Hs.18103	5	DNA binding intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
200617_at	0.393	7.643	2.676	1.711e-02	0.266	-3.166	MLEC	malectin	12	119609331	NM_014730	9761	12q24.31	Hs.714322	4	endoplasmic reticulum carbohydrate metabolic process membrane integral to membrane carbohydrate binding
208972_s_at	0.389	11.130	2.676	1.712e-02	0.266	-3.166	ATP5G1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)	17	44325146	AL080089	516	17q21.32	Hs.80986	16	transporter activity mitochondrion mitochondrial proton-transporting ATP synthase complex ion transport lipid binding hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting ATP synthase complex, coupling factor F(o)	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
215543_s_at	-0.596	7.717	-2.676	1.712e-02	0.266	-3.166	LARGE	like-glycosyltransferase	22	-31999061	AB011181	9215	22q12.3	Hs.474667	18	Golgi apparatus N-acetylglucosamine metabolic process protein amino acid glycosylation glycosphingolipid biosynthetic process acetylglucosaminyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane muscle maintenance
200008_s_at	-0.803	7.612	-2.676	1.713e-02	0.266	-3.166	GDI2	GDP dissociation inhibitor 2	10	-5847191	D13988	2665	10p15	Hs.299055	16	Rab GDP-dissociation inhibitor activity GTPase activator activity cytoplasm signal transduction cell surface protein transport membrane regulation of GTPase activity
226727_at	0.328	7.745	2.675	1.713e-02	0.266	-3.167	CISD3	CDGSH iron sulfur domain 3	17	34140035	BG171264	284106	17q12	Hs.713595	4	iron ion binding mitochondrion metal ion binding 2 iron, 2 sulfur cluster binding
210817_s_at	-0.583	9.150	-2.675	1.714e-02	0.266	-3.167	CALCOCO2	calcium binding and coiled-coil domain 2	17	44263370	BC004130	10241	17q21.32	Hs.514920	11	protein binding soluble fraction nucleus cytoplasm Golgi apparatus cytoskeleton viral reproduction response to interferon-gamma protein homodimerization activity perinuclear region of cytoplasm
202866_at	-0.322	7.302	-2.675	1.715e-02	0.266	-3.168	DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12	10	-73762593	BG283782	54788	10q22.1	Hs.696014	7	endoplasmic reticulum protein folding membrane integral to membrane heat shock protein binding unfolded protein binding
219718_at	0.627	7.890	2.675	1.715e-02	0.266	-3.168	FGGY	FGGY carbohydrate kinase domain containing	1	59535212	NM_018291	55277	1p32.1	Hs.444301	7	molecular_function cellular_component carbohydrate metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor neuron maintenance
225440_at	-0.690	8.029	-2.675	1.716e-02	0.266	-3.168	AGPAT3	1-acylglycerol-3-phosphate O-acyltransferase 3	21	44109543, 44169706	BE737251	56894	21q22.3	Hs.248785	9	1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum cytosol plasma membrane metabolic process acyltransferase activity phospholipid biosynthetic process integral to membrane transferase activity phospholipid:diacylglycerol acyltransferase activity	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways
207895_at	0.327	4.418	2.674	1.719e-02	0.267	-3.170	NAALADL1	N-acetylated alpha-linked acidic dipeptidase-like 1	11	-64568870	NM_005468	10004	11q12	Hs.13967	3	carboxypeptidase activity plasma membrane proteolysis peptidase activity metallopeptidase activity zinc ion binding integral to membrane dipeptidase activity metal ion binding
200941_at	-0.446	7.861	-2.674	1.719e-02	0.267	-3.170	HSBP1	heat shock factor binding protein 1	16	82399093	AK026575	3281	16q23.3	Hs.250899 Hs.705549	8	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus
213126_at	-0.446	4.648	-2.674	1.720e-02	0.267	-3.170	MED8	mediator complex subunit 8	1	-43622983, -43622174	BG230758	112950	1p34.2	Hs.301756	12	nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity modification-dependent protein catabolic process regulation of transcription
1555704_at	0.345	3.831	2.674	1.720e-02	0.267	-3.170	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	16	65195702, 65195713, 65196067	AY166714	123920	16q21	Hs.298198	7	cytokine activity extracellular space chemotaxis membrane integral to membrane
207243_s_at	-0.543	11.436	-2.673	1.722e-02	0.267	-3.171	CALM2	calmodulin 2 (phosphorylase kinase, delta)	2	-47240725	NM_001743	805	2p21	Hs.468442	52		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
218821_at	-0.432	7.060	-2.672	1.723e-02	0.267	-3.172	NPEPL1	aminopeptidase-like 1	20	56701267	AL139349	79716	20q13.32	Hs.554211 Hs.654868	7	aminopeptidase activity intracellular proteolysis peptidase activity zinc ion binding manganese ion binding metal ion binding
206860_s_at	-0.568	7.440	-2.672	1.724e-02	0.267	-3.172	MIOS	missing oocyte, meiosis regulator, homolog (Drosophila)	7	7573140	NM_019005	54468	7p22-p21	Hs.520215	4
203849_s_at	0.297	4.367	2.672	1.725e-02	0.267	-3.173	KIF1A	kinesin family member 1A	2	-241301856	BG473130	547	2q37.3	Hs.516802	21	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement anterograde axon cargo transport
229927_at	0.338	3.880	2.671	1.728e-02	0.267	-3.174	LEMD1	LEM domain containing 1	1	-203617135	BE222220	93273	1q32.1	Hs.655520	2	nuclear envelope membrane integral to membrane
243318_at	-0.359	6.640	-2.671	1.728e-02	0.267	-3.174	DCAF8	DDB1 and CUL4 associated factor 8	1	-158475636, -158475636, -158452128, -158452128	AI208342	50717	1q22-q23	Hs.632447	10	protein binding
226573_at	0.802	5.920	2.671	1.729e-02	0.267	-3.175	DIRAS1	DIRAS family, GTP-binding RAS-like 1	19	-2665564	AI829795	148252	19p13.3	Hs.172753	6	nucleotide binding GTP binding intracellular plasma membrane small GTPase mediated signal transduction
227013_at	-0.548	8.565	-2.671	1.729e-02	0.267	-3.175	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	13	-20445175	AI535735	26524	13q11-q12	Hs.78960	17	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding spindle pole protein serine/threonine kinase activity ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation cell cycle mitosis protein kinase cascade hormone-mediated signaling transferase activity negative regulation of cyclin-dependent protein kinase activity cell division
1562841_at	0.316	4.887	2.671	1.729e-02	0.267	-3.175	LOC339666	hypothetical protein LOC339666	22		BC041349	339666	22q12.3	Hs.654761	1
228162_at	-0.422	5.573	-2.670	1.730e-02	0.267	-3.176	ESD	esterase D/formylglutathione hydrolase	13	-46243391	AA193515	2098	13q14.1-q14.2	Hs.432491	27	carboxylesterase activity cytoplasm biological_process cytoplasmic membrane-bounded vesicle S-formylglutathione hydrolase activity
1554020_at	-0.512	3.793	-2.670	1.731e-02	0.267	-3.176	BICD1	bicaudal D homolog 1 (Drosophila)	12	32151451	BC010091	636	12p11.2-p11.1	Hs.505202	17	structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis
221249_s_at	0.363	5.597	2.670	1.732e-02	0.267	-3.176	FAM117A	family with sequence similarity 117, member A	17	-45142687	NM_030802	81558	17q21.33	Hs.514308	2
218579_s_at	-0.336	4.886	-2.670	1.732e-02	0.267	-3.176	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	20	37024413	NM_021931	60625	20q11.22-q12	Hs.444520	5	nucleotide binding nucleic acid binding helicase activity ATP binding spliceosomal complex mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity
207771_at	0.253	5.648	2.670	1.732e-02	0.267	-3.177	SLC5A2	solute carrier family 5 (sodium/glucose cotransporter), member 2	16	31401939	NM_003041	6524	16p12-p11	Hs.709195	9	transporter activity low-affinity glucose:sodium symporter activity carbohydrate metabolic process ion transport sodium ion transport carbohydrate transport symporter activity glucose transport membrane integral to membrane sodium ion binding brush border membrane
232662_x_at	0.403	7.435	2.670	1.733e-02	0.267	-3.177	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	AK022598	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
236657_at	-0.684	5.994	-2.670	1.734e-02	0.267	-3.177	LOC100130506	hypothetical protein LOC100130506	2		AW014647	100130506
244682_at	0.274	2.545	2.670	1.734e-02	0.267	-3.177	CAMSAP1	calmodulin regulated spectrin-associated protein 1	9	-137840153	H11471	157922	9q34.3	Hs.522493	2
214869_x_at	-0.282	6.059	-2.669	1.735e-02	0.267	-3.178	GAPVD1	GTPase activating protein and VPS9 domains 1	9	127063931	AK021533	26130	9q33.3	Hs.495134	9	guanyl-nucleotide exchange factor activity GTPase activator activity intracellular endosome cytosol endocytosis signal transduction membrane GTPase activating protein binding regulation of small GTPase mediated signal transduction regulation of protein transport
241793_at	-1.360	9.582	-2.669	1.736e-02	0.267	-3.178	ZMYND17	zinc finger, MYND-type containing 17	10	-74853342	BE674227	118490	10q22.2	Hs.631823	2	zinc ion binding metal ion binding
1554256_a_at	0.446	3.950	2.669	1.736e-02	0.267	-3.179	PCNXL2	pecanex-like 2 (Drosophila)	1	-231186504	BC008300	80003	1q42.2	Hs.370605	4	membrane integral to membrane
233480_at	-0.408	3.492	-2.669	1.737e-02	0.267	-3.179	TMEM43	transmembrane protein 43	3	14141440	AK026869	79188	3p25.1	Hs.517817	18	nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane
228459_at	0.254	3.103	2.668	1.737e-02	0.267	-3.179	FAM84A	family with sequence similarity 84, member A	2	14690306	BF063776	151354	2p24.3	Hs.260855	6
1567297_at	0.272	4.625	2.668	1.737e-02	0.267	-3.179	OR13C4	olfactory receptor, family 13, subfamily C, member 4	9	-106328354	X64991	138804	9q31.1	Hs.553601	5	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
201514_s_at	-0.740	6.900	-2.668	1.738e-02	0.267	-3.180	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	NM_005754	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
1564251_at	0.321	5.359	2.668	1.739e-02	0.267	-3.180	EMID1	EMI domain containing 1	22	27931952	AL831910	129080	22q12.2	Hs.289106	5	protein binding extracellular region proteinaceous extracellular matrix endoplasmic reticulum Golgi apparatus
217729_s_at	-0.431	8.376	-2.668	1.739e-02	0.267	-3.180	AES	amino-terminal enhancer of split	19	-3003907, -3003907	NM_001130	166	19p13.3	Hs.515053	24	skeletal system development transcription corepressor activity protein binding nucleus regulation of transcription from RNA polymerase II promoter multicellular organismal development organ morphogenesis negative regulation of specific transcription from RNA polymerase II promoter Wnt receptor signaling pathway negative regulation of transcription transcription regulator activity cellular response to extracellular stimulus negative regulation of protein binding regulation of growth negative regulation of response to cytokine stimulus response to interleukin-1
226660_at	-0.521	8.434	-2.668	1.740e-02	0.267	-3.180	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	AI142096	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
211549_s_at	-0.335	3.008	-2.668	1.740e-02	0.267	-3.180	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)	4	-175647902, -175647902	U63296	3248	4q34-q35	Hs.596913	47	prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction
212665_at	-0.398	7.184	-2.668	1.740e-02	0.267	-3.180	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	3	157875072	AL556438	25976	3q25.31	Hs.719169	11	vasculogenesis kidney development nucleic acid binding NAD+ ADP-ribosyltransferase activity protein binding nucleus protein amino acid ADP-ribosylation nitrogen compound metabolic process zinc ion binding post-embryonic development transferase activity, transferring glycosyl groups hemopoiesis multicellular organismal metabolic process metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development palate development face morphogenesis
226168_at	-0.323	6.754	-2.667	1.741e-02	0.267	-3.181	ZFAND2B	zinc finger, AN1-type domain 2B	2	219779781	AA524690	130617	2q35	Hs.534540	6	protein binding zinc ion binding metal ion binding
203961_at	0.437	4.351	2.667	1.741e-02	0.267	-3.181	NEBL	nebulette	10	-21108910, -21108910	AL157398	10529	10p12	Hs.5025	15	actin binding structural constituent of muscle regulation of actin filament length
202669_s_at	0.356	5.383	2.667	1.741e-02	0.267	-3.181	EFNB2	ephrin-B2	13	-105940096	U16797	1948	13q33	Hs.149239	71	lymph vessel development plasma membrane integral to plasma membrane cell-cell signaling multicellular organismal development nervous system development organ morphogenesis cell differentiation interspecies interaction between organisms ephrin receptor binding	Axon guidance
243452_at	0.467	3.711	2.667	1.742e-02	0.267	-3.181	LOC646778	hypothetical LOC646778	18		BE895304	646778	18q12.1	Hs.631680	1
222619_at	-0.537	6.840	-2.667	1.742e-02	0.267	-3.181	ZNF281	zinc finger protein 281	1	-198642042	AU150752	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
227357_at	-0.462	7.546	-2.667	1.743e-02	0.267	-3.182	MAP3K7IP3	mitogen-activated protein kinase kinase kinase 7 interacting protein 3	X	-30755479	BF593914	257397	Xp21.2	Hs.188256	10	protein binding intracellular zinc ion binding metal ion binding
202440_s_at	-0.516	5.903	-2.667	1.743e-02	0.267	-3.182	ST5	suppression of tumorigenicity 5	11	-8671474, -8671474, -8671474	NM_005418	6764	11p15	Hs.117715	11	protein binding
218076_s_at	-0.413	7.620	-2.666	1.745e-02	0.267	-3.183	ARHGAP17	Rho GTPase activating protein 17	16	-24838212	NM_018054	55114	16p12.1	Hs.373793	8	GTPase activator activity protein binding intracellular cytoplasm tight junction signal transduction membrane SH3 domain binding cell junction
223231_at	-0.322	8.569	-2.666	1.745e-02	0.267	-3.183	TATDN1	TatD DNase domain containing 1	8	-125569915	AF212250	83940	8q24.13	Hs.170568	3	nuclease activity nucleus hydrolase activity endodeoxyribonuclease activity, producing 5'-phosphomonoesters
218241_at	-0.400	7.242	-2.666	1.746e-02	0.267	-3.183	GOLGA5	golgi autoantigen, golgin subfamily a, 5	14	92330402	NM_005113	9950	14q32.12-q32.13	Hs.104320	14	Golgi membrane protein tyrosine kinase activity protein binding ATP binding Golgi apparatus cis-Golgi network protein amino acid phosphorylation Golgi organization membrane integral to membrane Rab GTPase binding Golgi cisterna protein homodimerization activity Golgi vesicle transport
226331_at	-0.303	7.064	-2.666	1.746e-02	0.267	-3.184	BBX	bobby sox homolog (Drosophila)	3	108724472	BF508813	56987	3q13.1	Hs.124366	11	DNA binding nucleus regulation of transcription
220239_at	-0.581	4.141	-2.666	1.746e-02	0.267	-3.184	KLHL7	kelch-like 7 (Drosophila)	7	23111877	NM_018846	55975	7p15.3	Hs.654817	9	protein binding nucleus nucleolus
204647_at	-0.817	8.045	-2.666	1.747e-02	0.267	-3.184	HOMER3	homer homolog 3 (Drosophila)	19	-18901009, -18901009, -18901009, -18901009, -18901009	NM_004838	9454	19p13.11	Hs.10326	16	protein binding cytoplasm plasma membrane protein targeting metabotropic glutamate receptor signaling pathway postsynaptic density cell junction synapse postsynaptic membrane
204324_s_at	-0.768	5.851	-2.666	1.747e-02	0.267	-3.184	GOLIM4	golgi integral membrane protein 4	3	-169210347	NM_014498	27333	3q26.2	Hs.143600	10	nucleus endosome Golgi apparatus Golgi lumen cis-Golgi network transport membrane integral to membrane endocytic vesicle
229530_at	0.378	5.619	2.664	1.753e-02	0.268	-3.187	GUCY1A3	guanylate cyclase 1, soluble, alpha 3	4	156807311, 156807311, 156807311, 156807598, 156807598, 156808264	BF002625	2982	4q31.1-q31.2 4q31.3-q33	Hs.24258	14	nucleotide binding guanylate cyclase activity receptor activity GTP binding cytoplasm nitric oxide mediated signal transduction guanylate cyclase complex, soluble regulation of blood pressure positive regulation of cGMP biosynthetic process response to defense-related host nitric oxide production relaxation of vascular smooth muscle	Purine metabolism Vascular smooth muscle contraction Gap junction Long-term depression
223925_s_at	-0.455	4.636	-2.664	1.754e-02	0.268	-3.188	LUZP6	leucine zipper protein 6	7	-135262042	AF130088	767558	7q33	Hs.654894	2
202137_s_at	-0.741	6.285	-2.663	1.755e-02	0.268	-3.188	ZMYND11	zinc finger, MYND domain containing 11	10	170423, 170423	NM_006624	10771	10p14	Hs.292265	17	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding nucleus cell cycle zinc ion binding cell proliferation regulation of transcription metal ion binding
210301_at	0.357	4.405	2.663	1.755e-02	0.268	-3.188	XDH	xanthine dehydrogenase	2	-31410691	U06117	7498	2p23.1	Hs.250	48	xanthine dehydrogenase activity xanthine oxidase activity xanthine oxidase activity iron ion binding peroxisome cytosol cytosol lactation electron carrier activity response to aluminum ion oxidoreductase activity molybdenum ion binding regulation of epithelial cell differentiation bone resorption metal ion binding FAD binding 2 iron, 2 sulfur cluster binding oxidation reduction	Purine metabolism Caffeine metabolism Drug metabolism - other enzymes Metabolic pathways
211489_at	0.342	2.974	2.662	1.760e-02	0.269	-3.191	ADRA1A	adrenergic, alpha-1A-, receptor	8	-26683138, -26679287, -26669829, -26661583	D32201	148	8p21-p11.2	Hs.709175	67	receptor activity G-protein coupled receptor activity adrenoceptor activity alpha1-adrenergic receptor activity alpha1-adrenergic receptor activity plasma membrane integral to plasma membrane apoptosis smooth muscle contraction signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade cell-cell signaling negative regulation of cell proliferation	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
220199_s_at	-0.610	5.831	-2.661	1.762e-02	0.269	-3.192	AIDA	axin interactor, dorsalization associated	1	-220907977	NM_022831	64853	1q41	Hs.156625 Hs.534965 Hs.707666	6	protein binding cellular_component multicellular organismal development dorsal/ventral pattern formation regulation of protein homodimerization activity negative regulation of JNK cascade
200736_s_at	-0.274	9.668	-2.661	1.762e-02	0.269	-3.192	GPX1	glutathione peroxidase 1	3	-49369612	NM_000581	2876	3p21.3	Hs.76686	126	temperature homeostasis release of cytochrome c from mitochondria endothelial cell development negative regulation of inflammatory response to antigenic stimulus glutathione peroxidase activity glutathione peroxidase activity cytoplasm mitochondrion cytosol lipid metabolic process triglyceride metabolic process glutathione metabolic process anti-apoptosis induction of apoptosis sensory perception of sound selenium binding proteasome inhibitor activity induction of apoptosis by oxidative stress response to xenobiotic stimulus response to symbiotic bacterium response to wounding response to toxin UV protection response to selenium ion response to gamma radiation myotube differentiation oxidoreductase activity SH3 domain binding protein amino acid oxidation response to hydroperoxide regulation of mammary gland epithelial cell proliferation regulation of gene expression, epigenetic vasodilation response to hydrogen peroxide hydrogen peroxide catabolic process negative regulation of caspase activity glutathione binding skeletal muscle regeneration regulation of neuron apoptosis blood vessel endothelial cell migration fat cell differentiation myoblast proliferation interaction with symbiont positive regulation of protein kinase B signaling cascade oxidation reduction heart contraction angiogenesis involved in wound healing	Glutathione metabolism Arachidonic acid metabolism Amyotrophic lateral sclerosis (ALS) Huntington's disease
219251_s_at	-0.319	7.125	-2.661	1.762e-02	0.269	-3.192	WDR60	WD repeat domain 60	7	158342029	NM_018051	55112	7q36.3	Hs.389945	7
209772_s_at	0.321	3.933	2.661	1.762e-02	0.269	-3.192	CD24	CD24 molecule	6	-19611913	X69397	100133941	6q21	Hs.644105 Hs.694721	65	response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation leukocyte migration during inflammatory response immune response-regulating cell surface receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptosis signal transducer activity protein binding membrane fraction plasma membrane oxygen and reactive oxygen species metabolic process heterophilic cell adhesion leukocyte adhesion elevation of cytosolic calcium ion concentration neuromuscular synaptic transmission negative regulation of neuroblast proliferation induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals apoptotic mitochondrial changes external side of plasma membrane Wnt receptor signaling pathway cell migration protein kinase binding carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity regulation of epithelial cell differentiation negative regulation of B cell proliferation neuron projection development anchored to membrane T cell costimulation anchored to external side of plasma membrane microvillus membrane B cell receptor transport into membrane raft chemokine receptor transport out of membrane raft negative regulation of transforming growth factor-beta3 production positive regulation of integrin activation positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPKKK cascade eukaryotic cell surface binding response to estrogen stimulus membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling cilium membrane
1563071_at	0.281	5.029	2.661	1.763e-02	0.269	-3.192	LOC100289061	hypothetical protein LOC100289061	1		BC038543	100289061	1q21.3	Hs.677561	1
207564_x_at	-0.606	6.670	-2.661	1.763e-02	0.269	-3.192	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	70669657	NM_003605	8473	Xq13	Hs.405410	47	protein binding nucleus cytoplasm cytosol protein amino acid O-linked glycosylation signal transduction response to nutrient acetylglucosaminyltransferase activity transferase activity, transferring glycosyl groups MLL5-L complex	O-Glycan biosynthesis Metabolic pathways
201539_s_at	-1.037	11.817	-2.661	1.765e-02	0.269	-3.193	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	U29538	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
243829_at	-0.442	4.988	-2.660	1.766e-02	0.269	-3.194	BRAF	v-raf murine sarcoma viral oncogene homolog B1	7	-140080281	AW613053	673	7q34	Hs.550061	427	nucleotide binding protein serine/threonine kinase activity receptor signaling protein activity protein binding ATP binding nucleus cytoplasm plasma membrane protein amino acid phosphorylation anti-apoptosis small GTPase mediated signal transduction zinc ion binding organ morphogenesis transferase activity diacylglycerol binding metal ion binding	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Focal adhesion Natural killer cell mediated cytotoxicity Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
1558217_at	0.239	3.771	2.660	1.768e-02	0.269	-3.195	SLFN13	schlafen family member 13	17	-30786227	AK074465	146857	17q12	Hs.462833	8	nucleotide binding ATP binding intracellular
225154_at	-0.275	8.403	-2.659	1.769e-02	0.269	-3.196	SYAP1	synapse associated protein 1, SAP47 homolog (Drosophila)	X	16647675	BG029566	94056	Xp22.2	Hs.605178	11	nucleus
238889_at	-0.340	2.954	-2.659	1.769e-02	0.269	-3.196	AGBL5	ATP/GTP binding protein-like 5	2	27127994, 27127994	AA045527	60509	2p23.3	Hs.138207	4	metallocarboxypeptidase activity nucleus cytoplasm proteolysis zinc ion binding
213490_s_at	-0.448	6.453	-2.659	1.770e-02	0.269	-3.196	MAP2K2	mitogen-activated protein kinase kinase 2	19	-4041319	AI762811	5605	19p13.3	Hs.465627	98	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding extracellular region protein amino acid phosphorylation Ras protein signal transduction transferase activity	MAPK signaling pathway ErbB signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Pathways in cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
202869_at	0.530	5.510	2.659	1.771e-02	0.269	-3.196	OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	12	111829121, 111829121	NM_016816	4938	12q24.1	Hs.524760	44	nucleotide binding RNA binding ATP binding nucleus cytoplasm mitochondrion endoplasmic reticulum microsome nucleobase, nucleoside, nucleotide and nucleic acid metabolic process immune response transferase activity nucleotidyltransferase activity
239831_at	0.380	4.036	2.659	1.772e-02	0.269	-3.197	TMEM106C	transmembrane protein 106C	12	46643596	R19392	79022	12q13.1	Hs.596726	5	molecular_function cellular_component endoplasmic reticulum biological_process membrane integral to membrane
201667_at	0.566	7.602	2.658	1.774e-02	0.269	-3.198	GJA1	gap junction protein, alpha 1, 43kDa	6	121798443	NM_000165	2697	6q21-q23.2	Hs.74471	181	signal transducer activity protein binding cytoplasm mitochondrial outer membrane lysosome early endosome multivesicular body endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane integral to plasma membrane fascia adherens connexon complex apoptosis muscle contraction cell-cell signaling heart development negative regulation of cell proliferation response to pH vascular transport ion transmembrane transporter activity ATP transport gap junction assembly SH3 domain binding transmembrane transporter activity cell junction PDZ domain binding Golgi-associated vesicle membrane positive regulation of I-kappaB kinase/NF-kappaB cascade membrane raft positive regulation of protein catabolic process neuron projection morphogenesis protein oligomerization regulation of calcium ion transport	Gap junction Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1557055_s_at	-0.743	6.704	-2.658	1.774e-02	0.269	-3.198	LOC643837	hypothetical LOC643837	1	752926	BC042880	643837	1p36.33	Hs.133183	2
221903_s_at	-0.911	6.645	-2.658	1.774e-02	0.269	-3.198	CYLD	cylindromatosis (turban tumor syndrome)	16	49333461, 49333529	BE046443	1540	16q12.1	Hs.578973	54	structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm	RIG-I-like receptor signaling pathway
228822_s_at	-0.473	7.776	-2.658	1.775e-02	0.269	-3.198	USP16	ubiquitin specific peptidase 16	21	29318808	AI435036	10600	21q22.11	Hs.99819	15	transcription coactivator activity cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity nucleus cytoplasm ubiquitin-dependent protein catabolic process cell cycle mitosis peptidase activity zinc ion binding chromatin modification histone deubiquitination histone binding ubiquitin binding regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization cell division
207142_at	-0.926	2.907	-2.658	1.775e-02	0.269	-3.198	KCNJ3	potassium inwardly-rectifying channel, subfamily J, member 3	2	155263338	NM_002239	3760	2q24.1	Hs.591606	24	voltage-gated ion channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex external side of plasma membrane G-protein activated inward rectifier potassium channel activity membrane integral to membrane T-tubule potassium ion binding
214641_at	-0.834	6.383	-2.658	1.776e-02	0.269	-3.199	COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	2	227737524	M81379	1285	2q36-q37	Hs.570065	77	integrin binding integrin binding extracellular matrix structural constituent protein binding extracellular region collagen collagen type IV induction of apoptosis activation of caspase activity cell adhesion cell surface receptor linked signal transduction sensory perception of sound blood circulation metalloendopeptidase inhibitor activity negative regulation of cell proliferation negative regulation of angiogenesis
223413_s_at	0.368	7.112	2.657	1.777e-02	0.269	-3.200	LYAR	Ly1 antibody reactive homolog (mouse)	4	-4320331, -4320331	AW958593	55646	4p16.3	Hs.425427	14	protein binding nucleus nucleolus zinc ion binding metal ion binding
201585_s_at	-0.304	7.075	-2.657	1.778e-02	0.269	-3.200	SFPQ	splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)	1	-35421789	BG035151	6421	1p34.3	Hs.355934	47	nucleotide binding DNA binding RNA binding protein binding nucleus DNA repair DNA recombination mRNA processing response to DNA damage stimulus RNA splicing nuclear matrix regulation of transcription
209781_s_at	-0.582	7.736	-2.656	1.780e-02	0.269	-3.201	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	8	136538897	AF069681	10656	8q24.2	Hs.444558	20	RNA binding protein binding nucleus nucleolus cytoplasm spermatogenesis SH3 domain binding regulation of transcription
208445_s_at	-0.318	7.390	-2.656	1.781e-02	0.269	-3.201	BAZ1B	bromodomain adjacent to zinc finger domain, 1B	7	-72492675	NM_023005	9031	7q11.23	Hs.719243	20	nucleotide binding condensed chromosome chromatin binding transcription factor activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus centromeric heterochromatin chromatin assembly or disassembly chromatin remodeling response to DNA damage stimulus zinc ion binding kinase activity histone phosphorylation chromatin remodeling complex transferase activity histone kinase activity regulation of transcription metal ion binding histone acetyl-lysine binding
1562239_at	0.375	4.648	2.656	1.781e-02	0.269	-3.201	SGSM1	small G protein signaling modulator 1	22	23532135	AB075821	129049	22q11.23	Hs.474397 Hs.620906	5	Rab GTPase activator activity intracellular Golgi apparatus regulation of Rab GTPase activity
205309_at	0.282	3.263	2.656	1.781e-02	0.269	-3.202	SMPDL3B	sphingomyelin phosphodiesterase, acid-like 3B	1	28134090, 28134090	NM_014474	27293	1p35.3	Hs.123659	3	sphingomyelin phosphodiesterase activity extracellular region extracellular space sphingomyelin catabolic process metabolic process hydrolase activity, acting on glycosyl bonds
1566926_at	0.262	4.400	2.656	1.781e-02	0.269	-3.202	C21orf104	chromosome 21 open reading frame 104	21		AJ011409	54748		Hs.548784
202843_at	-0.622	6.201	-2.655	1.785e-02	0.270	-3.203	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	NM_012328	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
200951_s_at	0.318	3.456	2.655	1.785e-02	0.270	-3.203	CCND2	cyclin D2	12	4253162	AW026491	894	12p13	Hs.376071	73	G1/S transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex positive regulation of protein amino acid phosphorylation protein binding nucleus positive regulation of cell proliferation protein kinase binding positive regulation of cyclin-dependent protein kinase activity cell division regulation of cell cycle	Cell cycle p53 signaling pathway Wnt signaling pathway Focal adhesion Jak-STAT signaling pathway
201289_at	-1.877	6.609	-2.655	1.785e-02	0.270	-3.204	CYR61	cysteine-rich, angiogenic inducer, 61	1	85819031	NM_001554	3491	1p31-p22	Hs.8867	82	regulation of cell growth patterning of blood vessels insulin-like growth factor binding extracellular region chemotaxis cell adhesion heparin binding cell proliferation anatomical structure morphogenesis positive regulation of cell-substrate adhesion extracellular matrix organization extracellular matrix binding
214363_s_at	-0.365	8.944	-2.655	1.786e-02	0.270	-3.204	MATR3	matrin 3	5	138637690, 138657253	AA129420	9782	5q31.2	Hs.268939	24	nucleotide binding RNA binding structural molecule activity protein binding intracellular nucleus nuclear inner membrane zinc ion binding nuclear matrix metal ion binding
223271_s_at	-0.424	5.914	-2.655	1.786e-02	0.270	-3.204	CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2	15	42506870	AF161543	51496	15q15.3-q21.1	Hs.497967	4	phosphoprotein phosphatase activity hydrolase activity
1569856_at	-0.397	3.032	-2.655	1.787e-02	0.270	-3.204	TPP2	tripeptidyl peptidase II	13	102047286	BC024905	7174	13q32-q33	Hs.432424	23	aminopeptidase activity serine-type endopeptidase activity cytoplasm proteolysis peptidase activity tripeptidyl-peptidase activity
201266_at	-0.437	8.584	-2.654	1.787e-02	0.270	-3.205	TXNRD1	thioredoxin reductase 1	12	103133688, 103204856	NM_003330	7296	12q23-q24.1	Hs.708065	60	thioredoxin-disulfide reductase activity thioredoxin-disulfide reductase activity nucleus cytoplasm cytosol transport signal transduction selenium binding electron carrier activity protein disulfide oxidoreductase activity oxidoreductase activity electron transport chain cell redox homeostasis FAD binding NADP or NADPH binding	Pyrimidine metabolism
200765_x_at	-0.478	8.070	-2.654	1.788e-02	0.270	-3.205	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	5	138117005	NM_001903	1495	5q31	Hs.534797 Hs.656653	70	structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding	Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC)
204605_at	-0.432	7.241	-2.654	1.788e-02	0.270	-3.205	CGRRF1	cell growth regulator with ring finger domain 1	14	54046336	NM_006568	10668	14q22.2	Hs.59106	5	protein binding response to stress cell cycle cell cycle arrest zinc ion binding negative regulation of cell proliferation negative regulation of cell growth metal ion binding
40020_at	0.315	4.436	2.654	1.789e-02	0.270	-3.206	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	3	-48648899	AB011536	1951	3p24.1-p21.2	Hs.631926	10	G-protein coupled receptor activity G-protein coupled receptor activity calcium ion binding protein binding plasma membrane homophilic cell adhesion neuropeptide signaling pathway multicellular organismal development integral to membrane integral to membrane
1553016_at	0.369	5.140	2.654	1.790e-02	0.270	-3.206	GPR113	G protein-coupled receptor 113	2	-26386316, -26384544, -26384544	NM_153835	165082	2p23.3	Hs.631878	7	G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
219630_at	-0.277	4.213	-2.653	1.791e-02	0.270	-3.207	PDZK1IP1	PDZK1 interacting protein 1	1	-47421847	NM_005764	10158	1p33	Hs.431099	16	membrane integral to membrane
226578_s_at	0.350	5.770	2.653	1.792e-02	0.270	-3.207	DUSP1	dual specificity phosphatase 1	5	-172127706	AW024420	1843	5q34	Hs.171695	73	non-membrane spanning protein tyrosine phosphatase activity protein binding protein amino acid dephosphorylation response to oxidative stress cell cycle intracellular signaling cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
214797_s_at	0.520	6.045	2.653	1.792e-02	0.270	-3.207	PCTK3	PCTAIRE protein kinase 3	1	203740349	BC000281	5129	1q31-q32	Hs.445402	13	nucleotide binding cyclin-dependent protein kinase activity signal transducer activity protein binding ATP binding cellular_component protein amino acid phosphorylation signal transduction transferase activity
215017_s_at	0.307	7.729	2.653	1.793e-02	0.270	-3.207	FNBP1L	formin binding protein 1-like	1	93686426	AW270932	54874	1p22.1	Hs.134060	15	cytoplasm cytoskeleton plasma membrane cell cortex endocytosis lipid binding cytoplasmic vesicle
223585_x_at	-0.789	5.827	-2.652	1.794e-02	0.270	-3.208	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	7	-32874302	AF151831	25948	7p14.3	Hs.372541	4	protein binding
202670_at	-0.484	8.542	-2.652	1.795e-02	0.270	-3.209	MAP2K1	mitogen-activated protein kinase kinase 1	15	64466264	AI571419	5604	15q22.1-q22.33	Hs.145442	171	nucleotide binding protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity receptor signaling protein tyrosine phosphatase activity protein binding ATP binding Golgi apparatus cytosol protein amino acid phosphorylation cell motion chemotaxis response to oxidative stress mitosis Ras protein signal transduction cell proliferation transferase activity neuron differentiation keratinocyte differentiation positive regulation of MAP kinase activity positive regulation of cell differentiation response to glucocorticoid stimulus	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation VEGF signaling pathway Focal adhesion Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
1556072_at	0.343	3.015	2.652	1.796e-02	0.270	-3.209	C22orf37	chromosome 22 open reading frame 37	22		AK097861	200298	22q11.21	Hs.517397	1
227766_at	-0.507	5.861	-2.652	1.796e-02	0.270	-3.209	LIG4	ligase IV, DNA, ATP-dependent	13	-107657792, -107657792, -107657792	AI829314	3981	13q33-q34	Hs.166091	82	single strand break repair nucleotide binding magnesium ion binding condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding DNA ligase (ATP) activity ATP binding intracellular nucleus cytoplasm plasma membrane focal adhesion DNA-dependent protein kinase-DNA ligase 4 complex DNA replication nucleotide-excision repair, DNA gap filling double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus cell cycle central nervous system development protein C-terminus binding cell proliferation response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination T cell receptor V(D)J recombination somatic stem cell maintenance negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA recombination DNA ligation during DNA repair DNA ligation during DNA repair chromosome organization cell division	Non-homologous end-joining
1563462_at	-1.345	3.885	-2.652	1.796e-02	0.270	-3.209	LOC285419	hypothetical LOC285419	4	124793389, 124914868	AL833449	285419	4q28.1	Hs.535763	1
204974_at	0.425	5.940	2.652	1.797e-02	0.270	-3.210	RAB3A	RAB3A, member RAS oncogene family	19	-18168610	AA988241	5864	19p13.2	Hs.27744	46	nucleotide binding respiratory system process GTPase activity protein binding protein binding GTP binding plasma membrane mitochondrion organization small GTPase mediated signal transduction neuromuscular synaptic transmission axonogenesis synaptic vesicle post-embryonic development protein transport synaptic vesicle exocytosis synaptic vesicle maturation lung development regulation of synaptic vesicle fusion to presynaptic membrane maintenance of presynaptic active zone structure sensory perception of touch response to electrical stimulus
216602_s_at	-0.602	6.123	-2.651	1.799e-02	0.270	-3.211	FARSA	phenylalanyl-tRNA synthetase, alpha subunit	19	-12894283	AD000092	2193	19p13.2	Hs.23111	10	tRNA binding nucleotide binding phenylalanine-tRNA ligase activity ATP binding soluble fraction cytoplasm phenylalanyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
218678_at	-0.970	7.924	-2.651	1.800e-02	0.270	-3.211	NES	nestin	1	-154905179	NM_024609	10763	1q23.1	Hs.527971	87	structural molecule activity cytoskeleton intermediate filament central nervous system development
227438_at	0.395	5.751	2.650	1.802e-02	0.270	-3.212	ALPK1	alpha-kinase 1	4	113437947	AI760166	80216	4q25	Hs.652825	10	protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation kinase activity transferase activity
218908_at	-0.517	5.716	-2.650	1.802e-02	0.270	-3.212	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	17	77528714	NM_024083	79058	17q25.3	Hs.298351	11	molecular_function protein binding cellular_component biological_process membrane
208535_x_at	0.310	5.642	2.650	1.802e-02	0.270	-3.212	COL13A1	collagen, type XIII, alpha 1	10	71231649, 71231649	NM_005203	1305	10q22	Hs.695934	16	morphogenesis of a branching structure endochondral ossification extracellular matrix structural constituent protein binding collagen type XIII plasma membrane cell-matrix adhesion multicellular organismal development biological_process heparin binding integral to membrane cell-cell adhesion cell differentiation
205087_at	-0.571	7.033	-2.649	1.805e-02	0.270	-3.213	RWDD3	RWD domain containing 3	1	95472298	NM_015485	25950	1p21.3	Hs.709591	11	protein binding nucleus cytoplasm
229144_at	-0.245	5.074	-2.649	1.806e-02	0.270	-3.214	RP1-21O18.1	kazrin	1	14797799, 14797799, 15123211, 15128882, 15145001	AA989362	23254	1p36.21	Hs.368823	10	nucleus cytoplasm cytoskeleton cell junction desmosome keratinization
218854_at	-0.507	6.368	-2.649	1.807e-02	0.270	-3.214	DSE	dermatan sulfate epimerase	6	116707975, 116798802	NM_013352	29940	6q22	Hs.486292	10	endoplasmic reticulum Golgi apparatus membrane integral to membrane isomerase activity dermatan sulfate biosynthetic process chondroitin-glucuronate 5-epimerase activity	Chondroitin sulfate biosynthesis
205541_s_at	-0.670	6.321	-2.649	1.807e-02	0.270	-3.214	GSPT2	G1 to S phase transition 2	X	51503236	NM_018094	23708	Xp11.22	Hs.59523	10	nucleotide binding translation release factor activity GTPase activity protein binding protein binding GTP binding cytoplasm translation cell cycle
223022_s_at	-0.501	7.699	-2.649	1.808e-02	0.270	-3.215	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	AL136684	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
225216_at	-0.402	7.241	-2.648	1.809e-02	0.270	-3.215	CXorf39	chromosome X open reading frame 39	X	103297956	AI590719	139231	Xq22.2	Hs.496535 Hs.592223	5
206875_s_at	-0.514	7.680	-2.648	1.809e-02	0.270	-3.216	SLK	STE20-like kinase (yeast)	10	105717459	NM_014720	9748	10q24.33	Hs.591922	16	nucleotide binding DNA binding nuclease activity protein serine/threonine kinase activity ATP binding cytoplasm plasma membrane nucleotide-excision repair protein amino acid phosphorylation apoptosis transferase activity
209780_at	-1.051	9.763	-2.648	1.810e-02	0.270	-3.216	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AL136883	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
229596_at	0.560	3.961	2.648	1.810e-02	0.270	-3.216	AMDHD1	amidohydrolase domain containing 1	12	94861201	AW271617	144193	12q23.1	Hs.424907	4	iron ion binding cytoplasm cytosol histidine metabolic process zinc ion binding histidine catabolic process to glutamate and formamide metal ion binding imidazolonepropionase activity	Histidine metabolism Metabolic pathways
239385_at	0.253	2.711	2.648	1.810e-02	0.270	-3.216	TFG	TRK-fused gene	3	101910849	AI150613	10342	3q12.2	Hs.518123	25	signal transducer activity cytoplasm identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade	Pathways in cancer Thyroid cancer
1559121_s_at	-0.562	5.342	-2.648	1.811e-02	0.270	-3.216	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	AI767566	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
224467_s_at	0.278	7.400	2.648	1.811e-02	0.270	-3.217	PDCD2L	programmed cell death 2-like	19	39587142	BC006146	84306	19q13.11	Hs.515344	5	cytoplasm
213970_at	-0.416	6.439	-2.648	1.812e-02	0.270	-3.217	RABL3	RAB, member of RAS oncogene family-like 3	3	-121888217	AA744682	285282	3q13.33	Hs.444360	1	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
204920_at	0.452	5.192	2.647	1.812e-02	0.270	-3.217	CPS1	carbamoyl-phosphate synthetase 1, mitochondrial	2	211050653, 211129570, 211166334	AF154830	1373	2q35	Hs.149252	23	urea cycle nucleotide binding carbamoyl-phosphate synthase (ammonia) activity protein binding ATP binding mitochondrion glycogen catabolic process glutamine metabolic process ligase activity citrulline biosynthetic process triglyceride catabolic process response to lipopolysaccharide mitochondrial nucleoid positive regulation of vasodilation nitric oxide metabolic process carbamoyl phosphate biosynthetic process	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Nitrogen metabolism Metabolic pathways
212598_at	-0.455	4.839	-2.647	1.812e-02	0.270	-3.217	WDFY3	WD repeat and FYVE domain containing 3	4	-85949008, -85809722, -85809722	BE348236	23001	4q21.23	Hs.480116	10	binding zinc ion binding membrane metal ion binding
215092_s_at	-0.460	4.446	-2.647	1.813e-02	0.270	-3.217	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	16	68156497	AJ005683	10725	16q22.1	Hs.371987	35	cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction excretion positive regulation of transcription from RNA polymerase II promoter	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
212197_x_at	-0.341	8.775	-2.647	1.815e-02	0.271	-3.218	MPRIP	myosin phosphatase Rho interacting protein	17	16886831, 16886831	AB020671	23164	17p11.2	Hs.462341	16	actin binding protein binding cytoplasm cytoskeleton
1557067_s_at	-0.445	6.063	-2.646	1.816e-02	0.271	-3.219	LUC7L	LUC7-like (S. cerevisiae)	16	-178974, -178970	AI744735	55692	16p13.3	Hs.16803	11	protein binding nucleus zinc ion binding negative regulation of striated muscle development metal ion binding RS domain binding
222407_s_at	-0.601	10.913	-2.646	1.817e-02	0.271	-3.219	ZFP106	zinc finger protein 106 homolog (mouse)	15	-40492312	AI493587	64397	15q15.1	Hs.511143	9	opioid peptide activity intracellular membrane fraction nucleus nucleolus cytosol zinc ion binding insulin receptor signaling pathway SH3 domain binding metal ion binding
225694_at	-0.500	5.206	-2.645	1.823e-02	0.271	-3.222	CRKRS	Cdc2-related kinase, arginine/serine-rich	17	34871264	AI823766	51755	17q12	Hs.416108	11	nucleotide binding RNA polymerase II transcription factor activity cyclin-dependent protein kinase activity ATP binding nucleus nuclear speck transferase activity protein amino acid autophosphorylation
231228_at	0.351	5.642	2.644	1.823e-02	0.271	-3.222	BCL2L1	BCL2-like 1	20	-29715921	AW263226	598	20q11.21	Hs.516966	295	release of cytochrome c from mitochondria nucleus mitochondrion mitochondrial outer membrane mitochondrial outer membrane anti-apoptosis negative regulation of survival gene product expression membrane integral to membrane response to cytokine stimulus identical protein binding regulation of mitochondrial membrane permeability regulation of mitochondrial membrane potential	Apoptosis Jak-STAT signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Pancreatic cancer Chronic myeloid leukemia Small cell lung cancer
202588_at	-0.367	8.800	-2.644	1.824e-02	0.272	-3.223	AK1	adenylate kinase 1	9	-129668579	NM_000476	203	9q34.1	Hs.175473	24	nucleotide binding adenylate kinase activity protein binding ATP binding nucleus cytoplasm mitochondrion cytosol plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle arrest transferase activity nucleoside kinase activity ATP metabolic process	Purine metabolism Metabolic pathways
235910_x_at	0.368	4.300	2.644	1.825e-02	0.272	-3.223	ZNF316	zinc finger protein 316	7		BE674951	100131017	7p22.1	Hs.112668	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212837_at	-0.346	7.849	-2.643	1.827e-02	0.272	-3.224	FAM175B	family with sequence similarity 175, member B	10	126480343	D63877	23172	10q26.13	Hs.280695	10	protein binding polyubiquitin binding BRISC complex
223567_at	0.282	3.275	2.643	1.828e-02	0.272	-3.225	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	19	-4493599	AB022433	10501	19p13.3	Hs.465642	4	receptor activity multicellular organismal development nervous system development membrane integral to membrane cell differentiation	Axon guidance
219131_at	-0.241	5.837	-2.643	1.829e-02	0.272	-3.225	UBIAD1	UbiA prenyltransferase domain containing 1	1	11255841	NM_013319	29914	1p36-p34.1	Hs.522933	15	prenyltransferase activity nucleus cytoplasm membrane integral to membrane
207000_s_at	-0.319	7.507	-2.643	1.830e-02	0.272	-3.226	PPP3CC	protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform	8	22354540	NM_005605	5533	8p21.3	Hs.655661	21	phosphoprotein phosphatase activity iron ion binding calmodulin binding cytosol zinc ion binding activation of pro-apoptotic gene products hydrolase activity metal ion binding	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
215424_s_at	-0.548	7.230	-2.642	1.832e-02	0.272	-3.227	SNW1	SNW domain containing 1	14	-77253696	AV689564	22938	14q24.3	Hs.445498	32	nuclear mRNA splicing, via spliceosome transcription coactivator activity Notch binding protein binding nucleus spliceosomal complex nucleolus regulation of transcription from RNA polymerase II promoter RNA splicing negative regulation of transcription	Notch signaling pathway
219701_at	-0.302	2.575	-2.642	1.833e-02	0.272	-3.227	TMOD2	tropomodulin 2 (neuronal)	15	49831049	NM_014548	29767	15q21.1-q21.2	Hs.513734 Hs.659839	7	actin binding tropomyosin binding cytoplasm cytoskeleton nerve-nerve synaptic transmission nervous system development learning or memory positive regulation of G-protein coupled receptor protein signaling pathway
244041_at	-0.378	4.882	-2.641	1.835e-02	0.272	-3.228	STX6	syntaxin 6	1	-179208798	AI884934	10228	1q25.3	Hs.518417	24	SNAP receptor activity membrane fraction early endosome Golgi apparatus trans-Golgi network plasma membrane intracellular protein transport vesicle fusion endosome organization integral to membrane clathrin-coated vesicle Golgi vesicle transport perinuclear region of cytoplasm	SNARE interactions in vesicular transport
201160_s_at	-0.252	12.837	-2.641	1.835e-02	0.272	-3.228	CSDA	cold shock domain protein A	12	-10742944	AL556190	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
228160_at	-0.420	6.157	-2.641	1.836e-02	0.272	-3.229	LOC339290	hypothetical LOC339290	18	5228098	AI433706	339290	18p11.31	Hs.643553 Hs.700799	4
217987_at	-0.489	8.972	-2.640	1.841e-02	0.273	-3.231	ASNSD1	asparagine synthetase domain containing 1	2	190234369	NM_019048	54529	2p24.3-q21.3	Hs.101364	3	asparagine synthase (glutamine-hydrolyzing) activity asparagine biosynthetic process glutamine metabolic process cellular amino acid biosynthetic process
215000_s_at	-0.691	9.974	-2.639	1.843e-02	0.273	-3.232	FEZ2	fasciculation and elongation protein zeta 2 (zygin II)	2	-36632904	AL117593	9637	2p21	Hs.258563	9	protein binding signal transduction nervous system development axon guidance
203700_s_at	-0.485	4.945	-2.638	1.846e-02	0.273	-3.234	DIO2	deiodinase, iodothyronine, type II	14	-79733621, -79733621	NM_013989	1734	14q24.2-q24.3	Hs.202354	61	selenocysteine incorporation thyroxine 5'-deiodinase activity thyroid hormone generation selenium binding membrane integral to membrane thyroid hormone catabolic process hormone biosynthetic process oxidation reduction
242114_at	-0.494	5.000	-2.638	1.846e-02	0.273	-3.234	BOLA2	bolA homolog 2 (E. coli)	16	-30111756, -29372414	BF088991	552900	16p11.2	Hs.444600 Hs.655267	5
1552482_at	0.258	2.332	2.638	1.847e-02	0.274	-3.234	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	2	-204014436, -204006783	NM_025252	65059	2q33	Hs.471162	13	nucleus cytoplasm cytoskeleton plasma membrane cell-matrix adhesion signal transduction lamellipodium filopodium
202309_at	0.353	8.723	2.638	1.848e-02	0.274	-3.234	MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	14	63924511	NM_005956	4522	14q24	Hs.652308	68	histidine biosynthetic process nucleotide binding formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity protein binding ATP binding cytoplasm mitochondrion purine nucleotide biosynthetic process histidine catabolic process one-carbon metabolic process cellular amino acid biosynthetic process methionine biosynthetic process folic acid and derivative biosynthetic process formyltetrahydrofolate dehydrogenase activity oxidoreductase activity hydrolase activity ligase activity oxidation reduction	Glyoxylate and dicarboxylate metabolism One carbon pool by folate Metabolic pathways
206947_at	-0.277	2.632	-2.638	1.848e-02	0.274	-3.234	B3GALT5	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5	21	39951123	NM_006057	10317	21q22.3	Hs.655094	19	endoplasmic reticulum Golgi apparatus protein amino acid glycosylation galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Glycosphingolipid biosynthesis - globo series Metabolic pathways
235457_at	0.597	5.597	2.637	1.851e-02	0.274	-3.236	MAML2	mastermind-like 2 (Drosophila)	11	-95351087	AI769569	84441	11q21	Hs.428214	17	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
217940_s_at	-0.383	7.691	-2.637	1.851e-02	0.274	-3.236	CARKD	carbohydrate kinase domain containing	13	110066008	NM_018210	55739	13q34	Hs.408324	5	molecular_function cellular_component biological_process
220164_s_at	0.587	8.534	2.637	1.851e-02	0.274	-3.236	FBXO40	F-box protein 40	3	122794859	NM_016298	51725	3q13.33	Hs.272564	7	molecular_function cellular_component biological_process zinc ion binding modification-dependent protein catabolic process metal ion binding
225843_at	0.288	6.218	2.637	1.851e-02	0.274	-3.236	ZFYVE19	zinc finger, FYVE domain containing 19	15	38886565	AW015263	84936	15q15.1	Hs.121676	8	protein binding zinc ion binding metal ion binding
1558214_s_at	-0.263	5.290	-2.637	1.852e-02	0.274	-3.236	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	5	138117005	BG330076	1495	5q31	Hs.534797 Hs.656653	70	structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding	Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1562031_at	-0.781	4.113	-2.637	1.852e-02	0.274	-3.237	JAK2	Janus kinase 2	9	4975244	BC043187	3717	9p24	Hs.656213	588	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding ATP binding nucleus cytoplasm cytoskeleton caveola apoptosis cell motion enzyme linked receptor protein signaling pathway tyrosine phosphorylation of STAT protein STAT protein nuclear translocation mesoderm development negative regulation of cell proliferation positive regulation of phosphoinositide 3-kinase cascade membrane transferase activity myeloid cell differentiation SH2 domain binding positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of DNA binding response to antibiotic positive regulation of peptidyl-tyrosine phosphorylation JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway	Chemokine signaling pathway Jak-STAT signaling pathway Adipocytokine signaling pathway
213718_at	-0.369	5.584	-2.637	1.852e-02	0.274	-3.237	RBM4	RNA binding motif protein 4	11	66162713	BE222257	5936	11q13	Hs.533712	20	nucleotide binding RNA binding nucleus nucleolus cytoplasm mRNA processing zinc ion binding RNA splicing metal ion binding
203183_s_at	0.250	4.668	2.637	1.852e-02	0.274	-3.237	SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	12	48765249	NM_003076	6602	12q13-q14	Hs.79335	23	transcription coactivator activity nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase II promoter SWI/SNF complex chromatin remodeling complex protein complex scaffold chromatin-mediated maintenance of transcription
226111_s_at	0.269	5.160	2.635	1.857e-02	0.274	-3.239	ZNF385A	zinc finger protein 385A	12	-53049186, -53049186	BF525395	25946	12q13.13	Hs.505653	8	DNA binding protein binding intracellular nucleus nucleolus cytoplasm zinc ion binding regulation of transcription metal ion binding
219545_at	0.238	5.266	2.635	1.859e-02	0.274	-3.240	KCTD14	potassium channel tetramerisation domain containing 14	11	-77404408	NM_023930	65987	11q14.1	Hs.709780	2	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
213898_at	0.312	4.066	2.635	1.859e-02	0.274	-3.240	RBM9	RNA binding motif protein 9	22	-34464728, -34464728	AW149379	23543	22q13.1	Hs.282998	18	nucleotide binding transcription corepressor activity RNA binding nucleus cytoplasm mRNA processing transcription factor binding RNA splicing RNA metabolic process negative regulation of transcription estrogen receptor signaling pathway regulation of cell proliferation
226064_s_at	0.487	5.869	2.635	1.859e-02	0.274	-3.240	DGAT2	diacylglycerol O-acyltransferase homolog 2 (mouse)	11	75157425	AW469523	84649	11q13.5	Hs.334305	16	2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity membrane fraction endoplasmic reticulum glycerol metabolic process acyltransferase activity lipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process	Glycerolipid metabolism Retinol metabolism Metabolic pathways
201860_s_at	0.433	5.248	2.634	1.861e-02	0.274	-3.241	PLAT	plasminogen activator, tissue	8	-42151392	NM_000930	5327	8p12	Hs.491582	209	serine-type endopeptidase activity extracellular region extracellular region extracellular space protein modification process proteolysis blood coagulation peptidase activity	Complement and coagulation cascades
205189_s_at	0.316	6.065	2.634	1.862e-02	0.274	-3.241	FANCC	Fanconi anemia, complementation group C	9	-96901156	NM_000136	2176	9q22.3	Hs.494529	77	protein binding nucleus cytoplasm cytosol DNA repair protein complex assembly response to DNA damage stimulus
211711_s_at	-0.801	4.674	-2.634	1.862e-02	0.274	-3.241	PTEN	phosphatase and tensin homolog	10	89613174	BC005821	5728	10q23.3	Hs.500466	557	regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade	Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer
210946_at	-0.387	8.838	-2.634	1.863e-02	0.274	-3.242	PPAP2A	phosphatidic acid phosphatase type 2A	5	-54756439	AF014403	8611	5q11	Hs.696231	20	membrane fraction cytosol plasma membrane integral to plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity negative regulation of cell proliferation germ cell migration hydrolase activity regulation of lipid metabolic process androgen receptor signaling pathway phospholipid dephosphorylation	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
227583_at	-0.229	5.526	-2.633	1.866e-02	0.275	-3.243	POP4	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	19	34789009	BE742653	10775	19q12	Hs.412870	13	ribonuclease MRP complex RNA binding ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolus rRNA processing mRNA cleavage tRNA processing hydrolase activity ribonuclease P complex identical protein binding
202606_s_at	-0.382	7.210	-2.633	1.867e-02	0.275	-3.244	TLK1	tousled-like kinase 1	2	-171555578, -171555578, -171555578	NM_012290	9874	2q31.1	Hs.719163	23	nucleotide binding regulation of chromatin assembly or disassembly protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus protein amino acid phosphorylation intracellular protein transport response to DNA damage stimulus cell cycle intracellular signaling cascade chromatin modification transferase activity
1554966_a_at	-0.651	7.394	-2.632	1.868e-02	0.275	-3.244	FILIP1L	filamin A interacting protein 1-like	3	-101049461, -101049461, -101034677	AF329092	11259	3q12.1	Hs.104672	8	molecular_function nucleus cytoplasm biological_process membrane myosin complex
233328_x_at	0.281	5.249	2.632	1.868e-02	0.275	-3.244	SLC17A9	solute carrier family 17, member 9	20	61054443	AL121673	63910	20q13.33	Hs.512686	7	transporter activity transport exocytosis membrane integral to membrane
209496_at	0.420	6.304	2.632	1.870e-02	0.275	-3.245	RARRES2	retinoic acid receptor responder (tazarotene induced) 2	7	-149666340	BC000069	5919	7q36.1	Hs.647064	22	retinoid metabolic process molecular_function extracellular region brown fat cell differentiation
1559101_at	0.340	5.469	2.631	1.872e-02	0.275	-3.246	FYN	FYN oncogene related to SRC, FGR, YES	6	-112089177, -112089177, -112089177	AK090692	2534	6q21	Hs.390567	326	nucleotide binding glycoprotein binding non-membrane spanning protein tyrosine kinase activity ATP binding endosome cytosol plasma membrane protein amino acid phosphorylation calcium ion transport protein kinase cascade multicellular organismal development learning feeding behavior transferase activity manganese ion binding identical protein binding interspecies interaction between organisms metal ion binding T cell receptor signaling pathway	Axon guidance Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway Prion diseases Pathogenic Escherichia coli infection - EHEC
202417_at	-0.515	8.783	-2.631	1.872e-02	0.275	-3.246	KEAP1	kelch-like ECH-associated protein 1	19	-10457795, -10457795	NM_012289	9817	19p13.2	Hs.465870	51	in utero embryonic development protein binding nucleus nucleolus cytoplasm endoplasmic reticulum centrosome transcription regulator activity regulation of transcription regulation of epidermal cell differentiation	Ubiquitin mediated proteolysis
205428_s_at	0.276	4.777	2.631	1.872e-02	0.275	-3.246	CALB2	calbindin 2	16	69950126, 69950126	NM_001740	794	16q22.2	Hs.106857	33	calcium ion binding gap junction
225300_at	-0.436	6.369	-2.631	1.875e-02	0.275	-3.247	C15orf23	chromosome 15 open reading frame 23	15	38462213	BF792864	90417	15q15.1	Hs.525796	6	protein binding nucleus
213325_at	-0.419	3.201	-2.630	1.876e-02	0.275	-3.248	PVRL3	poliovirus receptor-related 3	3	112273554	AA129716	25945	3q13	Hs.293917	9	plasma membrane cell adhesion homophilic cell adhesion integral to membrane protein homodimerization activity cell adhesion molecule binding	Cell adhesion molecules (CAMs) Adherens junction
226324_s_at	0.245	5.946	2.630	1.876e-02	0.275	-3.248	IFT172	intraflagellar transport 172 homolog (Chlamydomonas)	2	-27520743	AB033005	26160	2p23.3	Hs.127401	4	neural tube formation protein binding cilium smoothened signaling pathway multicellular organismal development determination of left/right symmetry dorsal/ventral pattern formation protein processing cilium assembly
204810_s_at	0.211	13.769	2.630	1.877e-02	0.275	-3.249	CKM	creatine kinase, muscle	19	-50501510	NM_001824	1158	19q13.2-q13.3	Hs.334347	43	nucleotide binding creatine kinase activity ATP binding cytoplasm cytosol creatine metabolic process phosphocreatine biosynthetic process	Arginine and proline metabolism Metabolic pathways
225238_at	-0.890	6.014	-2.629	1.879e-02	0.276	-3.249	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BF435123	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
219400_at	0.283	5.054	2.629	1.880e-02	0.276	-3.250	CNTNAP1	contactin associated protein 1	17	38088157	NM_003632	8506	17q21	Hs.408730	10	receptor activity SH3/SH2 adaptor activity receptor binding integral to plasma membrane cell adhesion signal transduction membrane SH3 domain binding paranode region of axon	Cell adhesion molecules (CAMs)
228765_at	-0.551	8.877	-2.629	1.880e-02	0.276	-3.250	GTF2IRD2	GTF2I repeat domain containing 2	7	-73848419	BG032651	84163	7q11.23	Hs.647017 Hs.647039	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription
228099_at	0.470	6.394	2.628	1.883e-02	0.276	-3.251	ZNF550	zinc finger protein 550	19	-62750154	AI805301	162972	19q13.43	Hs.180257	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231509_at	0.334	4.313	2.628	1.885e-02	0.276	-3.252	C7orf16	chromosome 7 open reading frame 16	7	31693323	AW614524	10842	7p15	Hs.227011	8	protein serine/threonine phosphatase inhibitor activity soluble fraction protein amino acid phosphorylation signal transduction protein kinase cascade central nervous system development behavior	Long-term depression
225179_at	-0.540	7.146	-2.627	1.888e-02	0.276	-3.254	UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	4	39376058	AA161140	3093	4p14	Hs.50308 Hs.714332	20	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding cytoplasm ubiquitin-dependent protein catabolic process ligase activity ubiquitin protein ligase binding post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
202260_s_at	0.347	5.791	2.627	1.888e-02	0.276	-3.254	STXBP1	syntaxin binding protein 1	9	129414306	NM_003165	6812	9q34.1	Hs.288229	38	protein binding cytoplasm mitochondrion vesicle docking during exocytosis axon target recognition protein transport membrane synaptic vesicle maturation vesicle-mediated transport negative regulation of synaptic transmission, GABAergic
214065_s_at	0.299	4.956	2.627	1.890e-02	0.276	-3.254	CIB2	calcium and integrin binding family member 2	15	-76184045	BG251252	10518	15q24	Hs.129867	6	calcium ion binding protein binding
244655_at	0.532	4.113	2.626	1.890e-02	0.276	-3.255	LOC100132798	similar to hCG1774772	15		W68045	100132798	15q26.2
204778_x_at	0.363	6.252	2.626	1.891e-02	0.276	-3.255	HOXB7	homeobox B7	17	-44039593	AW102783	3217	17q21.3	Hs.436181	39	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation myeloid cell differentiation sequence-specific DNA binding embryonic skeletal system morphogenesis
215167_at	0.741	6.711	2.626	1.891e-02	0.276	-3.255	MED14	mediator complex subunit 14	X	-40393738	BE567032	9282	Xp11.4-p11.2	Hs.407604	33	receptor activity protein binding nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
216887_s_at	-0.569	11.269	-2.626	1.893e-02	0.276	-3.256	LDB3	LIM domain binding 3	10	88418300, 88418405, 88418405	AJ133768	11155	10q22.3-q23.2	Hs.657271	15	protein binding cytoplasm cytoskeleton zinc ion binding Z disc pseudopodium metal ion binding perinuclear region of cytoplasm
227828_s_at	0.397	4.614	2.625	1.894e-02	0.276	-3.256	FAM176A	family with sequence similarity 176, member A	2	-75572951, -75572951	AV700753	84141	2p12	Hs.302346	9	cytoplasm lysosome endoplasmic reticulum plasma membrane autophagy apoptosis integral to membrane
221822_at	-0.521	6.879	-2.625	1.894e-02	0.276	-3.256	CCDC101	coiled-coil domain containing 101	16	28472749	BE544663	112869	16p11.2	Hs.655476	6	nucleus regulation of transcription
200071_at	-0.594	8.339	-2.625	1.894e-02	0.276	-3.257	SMNDC1	survival motor neuron domain containing 1	10	-112042787	BF224259	10285	10q23	Hs.632093	12	spliceosome assembly RNA binding protein binding nucleus spliceosomal complex cytoplasm mRNA processing apoptosis induction of apoptosis RNA splicing Cajal body nuclear speck RNA splicing factor activity, transesterification mechanism
218091_at	-0.312	6.986	-2.625	1.895e-02	0.276	-3.257	AGFG1	ArfGAP with FG repeats 1	2	228045131	AI989512	3267	2q36.3	Hs.352962	29	DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding
1558705_at	0.370	5.991	2.625	1.896e-02	0.276	-3.257	ATOH8	atonal homolog 8 (Drosophila)	2	85834419	AL831857	84913	2p11.2	Hs.135569 Hs.436464	5	DNA binding nucleus multicellular organismal development nervous system development cell differentiation transcription regulator activity regulation of transcription
202432_at	-0.712	11.048	-2.625	1.896e-02	0.276	-3.257	PPP3CB	protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform	10	-74866569	NM_021132	5532	10q21-q22	Hs.500067	29	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding calcineurin complex signal transduction zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
229039_at	0.357	4.974	2.625	1.896e-02	0.276	-3.257	SYN2	synapsin II	3	12020861, 12020861	BE220333	6854	3p25	Hs.445503	22	catalytic activity protein binding ATP binding synaptic transmission neurotransmitter secretion cell junction synaptic vesicle membrane synapse
242002_at	0.447	4.931	2.625	1.897e-02	0.276	-3.258	NKAIN2	Na+/K+ transporting ATPase interacting 2	6	124166767	N62814	154215	6q21	Hs.656604	6	plasma membrane integral to membrane
204469_at	0.283	2.139	2.624	1.898e-02	0.276	-3.258	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	7	121300394	NM_002851	5803	7q31.3	Hs.489824	42	transmembrane receptor protein tyrosine phosphatase activity protein binding cellular_component integral to plasma membrane protein amino acid dephosphorylation central nervous system development biological_process protein tyrosine/threonine phosphatase activity membrane hydrolase activity	Epithelial cell signaling in Helicobacter pylori infection
226960_at	0.320	4.462	2.624	1.898e-02	0.276	-3.258	CXCL17	chemokine (C-X-C motif) ligand 17	19	-47624534	AW471176	284340	19q13.2	Hs.445586	6	angiogenesis extracellular region chemotaxis multicellular organismal development cell differentiation
213215_at	-0.385	7.231	-2.624	1.898e-02	0.276	-3.259	AP3S2	adaptor-related protein complex 3, sigma 2 subunit	15	-88174834	AI910895	10239	15q26.1	Hs.632161	14	protein binding Golgi apparatus intracellular protein transport protein transporter activity membrane vesicle-mediated transport membrane coat cytoplasmic vesicle	Lysosome
1564300_at	0.358	3.458	2.624	1.899e-02	0.276	-3.259	LOC100129058	similar to hCG2038656	3		AK097471	100129058	3p21.2		1
1554949_at	0.302	5.454	2.623	1.902e-02	0.277	-3.260	LOC554174	hypothetical LOC554174	22		BC009388	554174	22q13.31	Hs.660824	1
212535_at	-0.301	8.997	-2.623	1.902e-02	0.277	-3.260	MEF2A	myocyte enhancer factor 2A	15	97923655, 97990705	AA142929	4205	15q26	Hs.268675	77	transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding
200961_at	-0.421	8.180	-2.623	1.902e-02	0.277	-3.260	SEPHS2	selenophosphate synthetase 2	16	-30362452	NM_012248	22928	16p11.2	Hs.718460	7	nucleotide binding selenide, water dikinase activity ATP binding cellular_component selenium binding selenocysteine biosynthetic process transferase activity	Selenoamino acid metabolism Metabolic pathways
223666_at	-0.398	5.137	-2.623	1.904e-02	0.277	-3.261	SNX5	sorting nexin 5	20	-17870243, -17870243	BC002724	27131	20p11	Hs.316890	14	protein binding cell communication protein transport phosphoinositide binding
211717_at	-0.513	6.045	-2.623	1.905e-02	0.277	-3.262	ANKRD40	ankyrin repeat domain 40	17	-46125550	BC005853	91369	17q21.33	Hs.463426	2
204698_at	0.427	4.385	2.623	1.905e-02	0.277	-3.262	ISG20	interferon stimulated exonuclease gene 20kDa	15	86983042	NM_002201	3669	15q26	Hs.459265	10	3'-5'-exoribonuclease activity DNA catabolic process, exonucleolytic RNA binding exonuclease activity intracellular nucleus nucleoplasm RNA catabolic process cell proliferation single-stranded DNA specific 3'-5' exodeoxyribonuclease activity exoribonuclease II activity response to virus PML body hydrolase activity manganese ion binding metal ion binding
203198_at	-0.378	5.619	-2.622	1.906e-02	0.277	-3.262	CDK9	cyclin-dependent kinase 9	9	129588125	NM_001261	1025	9q34.1	Hs.150423 Hs.706809	172	nucleotide binding DNA binding cyclin-dependent protein kinase activity protein binding ATP binding nucleus nucleoplasm nucleolus transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter protein amino acid phosphorylation transcription elongation factor complex cell proliferation RNA polymerase II carboxy-terminal domain kinase activity transferase activity snRNA binding regulation of transcription
210976_s_at	-0.563	12.191	-2.622	1.907e-02	0.277	-3.263	PFKM	phosphofructokinase, muscle	12	46799294	U24183	5213	12q13.3	Hs.75160	35	nucleotide binding magnesium ion binding 6-phosphofructokinase activity 6-phosphofructokinase activity 6-phosphofructokinase activity ATP binding sugar binding soluble fraction cytoplasm cytosol cytosol 6-phosphofructokinase complex fructose 6-phosphate metabolic process glycolysis protein C-terminus binding kinase activity apical plasma membrane transferase activity kinase binding fructose 1,6-bisphosphate metabolic process positive regulation of insulin secretion glucose homeostasis identical protein binding muscle maintenance protein oligomerization fructose-6-phosphate binding	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Galactose metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
37425_g_at	0.341	5.564	2.622	1.907e-02	0.277	-3.263	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AB029343	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
211317_s_at	-0.630	7.298	-2.622	1.907e-02	0.277	-3.263	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	AF041461	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
235353_at	0.303	3.611	2.622	1.908e-02	0.277	-3.263	KIAA0746	KIAA0746 protein	4	-25358146	AI887866	23231	4p15.2	Hs.479384	5	binding membrane integral to membrane
210460_s_at	-0.504	10.033	-2.622	1.909e-02	0.277	-3.263	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	AB033605	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
226640_at	-0.315	5.747	-2.621	1.909e-02	0.277	-3.264	DAGLB	diacylglycerol lipase, beta	7	-6415272	AA015606	221955	7p22.1	Hs.487498	9	triacylglycerol lipase activity calcium ion binding plasma membrane integral to membrane lipid catabolic process hydrolase activity
203978_at	-0.311	7.047	-2.620	1.914e-02	0.277	-3.266	NUBP1	nucleotide binding protein 1 (MinD homolog, E. coli)	16	10745198	NM_002484	4682	16p13.13	Hs.81469	9	nucleotide binding protein binding ATP binding cytosol cellular iron ion homeostasis cell growth iron-sulfur cluster assembly nucleoside-triphosphatase activity iron-sulfur cluster binding
221763_at	-0.556	7.283	-2.620	1.915e-02	0.277	-3.266	JMJD1C	jumonji domain containing 1C	10	-64596993, -64596993	AI694023	221037	10q21.3	Hs.413416	10	iron ion binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding thyroid hormone receptor binding oxidation reduction
234926_s_at	-0.358	8.953	-2.620	1.915e-02	0.277	-3.267	C20orf43	chromosome 20 open reading frame 43	20	54477053	AK026118	51507	20q13.31	Hs.517134	10	molecular_function cellular_component biological_process
213842_x_at	-0.379	7.885	-2.620	1.916e-02	0.277	-3.267	NSUN5C	NOL1/NOP2/Sun domain family, member 5C	7	-72056767	AK021688	260294	7q11.23	Hs.510927	5	methyltransferase activity transferase activity
223050_s_at	-0.355	7.869	-2.619	1.917e-02	0.277	-3.267	FBXW5	F-box and WD repeat domain containing 5	9	-138954707	BC000850	54461	9q34.3	Hs.522507	12	protein binding modification-dependent protein catabolic process
203165_s_at	-0.306	3.555	-2.619	1.917e-02	0.277	-3.267	SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1	3	-157028064	NM_004733	9197	3q25.31	Hs.478031	5	membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane transport cell death acetyl-CoA transporter activity membrane	Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
223981_at	-0.479	4.197	-2.619	1.917e-02	0.277	-3.268	NIN	ninein (GSK3B interacting protein)	14	-50263700, -50262296, -50262296, -50256230	AF223937	51199	14q22.1	Hs.310429	23	nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization
1552362_a_at	0.316	6.237	2.619	1.918e-02	0.277	-3.268	LEAP2	liver expressed antimicrobial peptide 2	5	132237256	NM_052971	116842	5q31.1	Hs.337588	3	extracellular region defense response to bacterium
1552790_a_at	-0.529	6.847	-2.619	1.919e-02	0.277	-3.268	SEC62	SEC62 homolog (S. cerevisiae)	3	171167273	NM_153039	7095	3q26.2	Hs.622596	10	receptor activity endoplasmic reticulum cytoskeleton cotranslational protein targeting to membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport
213666_at	0.384	4.713	2.619	1.919e-02	0.277	-3.268	SEPT6	septin 6	X	-118634936, -118633715	AK026589	23157	Xq24	Hs.496666	22	nucleotide binding cytokinesis protein binding protein binding GTP binding cellular_component cell cycle septin complex
222498_at	-0.354	6.641	-2.618	1.924e-02	0.278	-3.271	AZI2	5-azacytidine induced 2	3	-28348183, -28338850	AI809206	64343	3p24.1	Hs.706676	12	cytoplasm	RIG-I-like receptor signaling pathway
220626_at	0.293	5.919	2.617	1.924e-02	0.278	-3.271	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	14	-93819402, -93819402	NM_016186	51156	14q32.13	Hs.118620	15	serine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity
230486_at	0.273	5.833	2.617	1.925e-02	0.278	-3.271	PCBP3	poly(rC) binding protein 3	21	46094302	BG025371	54039	21q22.3	Hs.474049	11	DNA binding RNA binding nucleus cytoplasm cytosol mRNA metabolic process ribonucleoprotein complex
225402_at	-0.547	4.989	-2.617	1.925e-02	0.278	-3.271	TP53RK	TP53 regulating kinase	20	-44746410	BG339450	112858	20q13.2	Hs.440263	12	nucleotide binding p53 binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity
204587_at	-0.376	5.974	-2.617	1.926e-02	0.278	-3.271	SLC25A14	solute carrier family 25 (mitochondrial carrier, brain), member 14	X	129301727	NM_003951	9016	Xq24	Hs.194686	13	binding mitochondrion mitochondrial inner membrane integral to plasma membrane transport mitochondrial transport aerobic respiration membrane
200866_s_at	-0.545	8.333	-2.617	1.926e-02	0.278	-3.272	PSAP	prosaposin	10	-73246060	M32221	5660	10q21-q22	Hs.523004 Hs.705948	76	extracellular space lysosome Golgi apparatus lipid metabolic process glycosphingolipid metabolic process lipid transport enzyme activator activity lipid binding integral to membrane	Lysosome
207131_x_at	0.443	5.201	2.617	1.926e-02	0.278	-3.272	GGT1	gamma-glutamyltransferase 1	22	23309717, 23329179, 23333654	NM_013430	2678	22q11.23	Hs.595809 Hs.645535	71	molecular_function gamma-glutamyltransferase activity protein binding cellular amino acid metabolic process glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity	Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways
228841_at	0.343	9.869	2.617	1.926e-02	0.278	-3.272	LYRM7	Lyrm7 homolog (mouse)	5	130534539	AW299250	90624	5q23.3	Hs.115467	4
218516_s_at	-0.384	5.423	-2.617	1.928e-02	0.278	-3.272	IMPAD1	inositol monophosphatase domain containing 1	8	-58033041	NM_017813	54928	8q12.1	Hs.716471	4	magnesium ion binding inositol-1(or 4)-monophosphatase activity membrane integral to membrane hydrolase activity
1555754_s_at	0.251	6.985	2.617	1.928e-02	0.278	-3.273	ATN1	atrophin 1	12	6903886, 6907740	Z22814	1822	12p13.31	Hs.143766	46	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus cytoplasm central nervous system development cell death toxin metabolic process protein domain specific binding toxin receptor binding
217724_at	-0.312	11.090	-2.616	1.930e-02	0.278	-3.273	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	AF131807	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
210532_s_at	0.256	11.689	2.616	1.930e-02	0.278	-3.274	C14orf2	chromosome 14 open reading frame 2	14	-103448377	AF116639	9556	14q32.33	Hs.109052	5	molecular_function cellular_component mitochondrion biological_process
222488_s_at	-0.317	9.175	-2.616	1.932e-02	0.278	-3.274	DCTN4	dynactin 4 (p62)	5	-150068502, -150068502	BE218028	51164	5q31-q32	Hs.675564	7	nucleus cytoplasm centrosome cytoskeleton protein N-terminus binding	Huntington's disease
233100_at	0.220	4.684	2.616	1.932e-02	0.278	-3.274	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1	7	36159360	AF150438	80820	7p14.2	Hs.487994 Hs.670591	4	DNA binding intracellular DNA repair
202593_s_at	-0.900	7.613	-2.615	1.932e-02	0.278	-3.274	GDE1	glycerophosphodiester phosphodiesterase 1	16	-19420515	NM_016641	51573	16p12-p11.2	Hs.512607	8	magnesium ion binding cytoplasm glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity glycerophosphoinositol glycerophosphodiesterase activity	Glycerophospholipid metabolism
224663_s_at	-0.381	11.620	-2.615	1.933e-02	0.278	-3.275	CFL2	cofilin 2 (muscle)	14	-34249338, -34249338, -34249338	BF576053	1073	14q12	Hs.180141	20	actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
227038_at	-0.697	5.370	-2.615	1.933e-02	0.278	-3.275	SGMS2	sphingomyelin synthase 2	4	108965169, 109033868	AI963083	166929	4q25	Hs.595423	13	Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process sphingolipid metabolic process sphingomyelin biosynthetic process kinase activity transferase activity integral to Golgi membrane sphingomyelin synthase activity ceramide cholinephosphotransferase activity	Sphingolipid metabolism Metabolic pathways
203064_s_at	-0.363	6.728	-2.615	1.934e-02	0.278	-3.275	FOXK2	forkhead box K2	17	78070882	NM_004514	3607	17q25	Hs.591140	11	magnesium ion binding transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding
1554187_at	-0.379	4.236	-2.615	1.934e-02	0.278	-3.275	LOC554206	hypothetical LOC554206	16		AK097891	554206	16p12.1	Hs.552959	2
226251_at	-0.420	5.926	-2.614	1.937e-02	0.278	-3.276	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	AW295549	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
229027_at	-0.938	5.002	-2.614	1.937e-02	0.278	-3.277	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AI241945	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
234980_at	-0.958	6.810	-2.614	1.937e-02	0.278	-3.277	TMEM56	transmembrane protein 56	1	95355481	AI004375	148534	1p21.3	Hs.483512	3	molecular_function cellular_component biological_process membrane integral to membrane
218436_at	-0.236	7.701	-2.614	1.937e-02	0.278	-3.277	SIL1	SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)	5	-138310308	NM_022464	64374	5q31	Hs.483521	15	binding endoplasmic reticulum endoplasmic reticulum lumen protein folding unfolded protein binding intracellular protein transmembrane transport
1554396_at	0.377	5.094	2.614	1.938e-02	0.278	-3.277	UEVLD	UEV and lactate/malate dehyrogenase domains	11	-18509819	BC011011	55293	11p15.1	Hs.407991	5	binding glycolysis metabolic process protein transport oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor small conjugating protein ligase activity modification-dependent protein catabolic process post-translational protein modification cellular carbohydrate metabolic process regulation of protein metabolic process
207335_x_at	0.374	10.749	2.614	1.939e-02	0.278	-3.278	ATP5I	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	4	-656224	NM_007100	521	4p16.3	Hs.85539	14	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
217790_s_at	-0.661	5.990	-2.613	1.941e-02	0.278	-3.278	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	3	-157741236	NM_007107	6747	3q25.31	Hs.518346	7	signal sequence binding protein binding endoplasmic reticulum translocon complex microsome cotranslational protein targeting to membrane membrane integral to membrane integral to endoplasmic reticulum membrane
234626_at	0.392	5.351	2.613	1.942e-02	0.278	-3.279	OR51I1	olfactory receptor, family 51, subfamily I, member 1	11	-5418375	AF137396	390063	11p15.4	Hs.553732	3	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
1553265_at	0.287	3.185	2.613	1.942e-02	0.278	-3.279	SLC23A3	solute carrier family 23 (nucleobase transporters), member 3	2	-219734426	NM_144712	151295	2q35	Hs.124565	5	transporter activity transport membrane integral to membrane
207993_s_at	-0.405	4.787	-2.613	1.943e-02	0.278	-3.279	CHP	calcium binding protein P22	15	39310728	NM_007236	11261	15q13.3	Hs.406234 Hs.706184	21	calcium ion binding cytoplasm potassium ion transport small GTPase mediated signal transduction potassium channel regulator activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
214270_s_at	-0.441	4.051	-2.613	1.943e-02	0.278	-3.280	MAPRE3	microtubule-associated protein, RP/EB family, member 3	2	27047028	AI885178	22924	2p23.3-p23.1	Hs.515860	13	small GTPase regulator activity cytoplasm microtubule cell cycle mitosis microtubule binding midbody positive regulation of gene-specific transcription cell division
209654_at	-0.488	7.434	-2.613	1.944e-02	0.278	-3.280	KIAA0947	KIAA0947	5	5475806	BC004902	23379	5p15.32	Hs.449296	3
204344_s_at	-0.655	6.373	-2.612	1.945e-02	0.278	-3.280	SEC23A	Sec23 homolog A (S. cerevisiae)	14	-38570873	NM_006364	10484	14q21.1	Hs.272927	18	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport zinc ion binding membrane membrane organization vesicle-mediated transport COPII vesicle coat perinuclear region of cytoplasm
222827_s_at	-1.282	11.393	-2.612	1.945e-02	0.278	-3.280	KBTBD10	kelch repeat and BTB (POZ) domain containing 10	2	170074457	AI126808	10324	2q31.1	Hs.50550	8	ruffle protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion striated muscle contraction modification-dependent protein catabolic process pseudopodium
209645_s_at	-0.697	5.820	-2.612	1.946e-02	0.278	-3.281	ALDH1B1	aldehyde dehydrogenase 1 family, member B1	9	38382701	NM_000692	219	9p11.1	Hs.436219	15	aldehyde dehydrogenase (NAD) activity mitochondrion mitochondrial matrix carbohydrate metabolic process oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
201359_at	-0.321	6.933	-2.612	1.946e-02	0.278	-3.281	COPB1	coatomer protein complex, subunit beta 1	11	-14435624, -14435624, -14435624	NM_016451	1315	11p15.2	Hs.339278	46	Golgi membrane structural molecule activity protein binding cytoplasm Golgi apparatus Golgi-associated vesicle cytosol cytosol intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat cytoplasmic vesicle interspecies interaction between organisms COPI coating of Golgi vesicle
238964_at	0.295	5.562	2.611	1.948e-02	0.278	-3.282	FIGN	fidgetin	2	-164172363	BE960968	55137	2q24.3	Hs.593650	4	nucleotide binding ATP binding nucleoside-triphosphatase activity
226470_at	-1.072	7.013	-2.611	1.950e-02	0.278	-3.283	GGT7	gamma-glutamyltransferase 7	20	-32896183	AL049709	2686	20q11.22	Hs.433738	9	gamma-glutamyltransferase activity glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity	Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways
205675_at	0.472	3.212	2.611	1.951e-02	0.278	-3.283	MTTP	microsomal triglyceride transfer protein	4	100704262	AI623321	4547	4q24	Hs.195799	93	lipid transporter activity endoplasmic reticulum protein amino acid lipidation lipid metabolic process triglyceride metabolic process lipid transport lipid binding lipoprotein metabolic process cholesterol homeostasis lipoprotein transport
235648_at	0.472	4.526	2.610	1.954e-02	0.278	-3.284	ZNF567	zinc finger protein 567	19	41872141	AA742659	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1554470_s_at	-0.707	6.802	-2.610	1.954e-02	0.278	-3.285	ZBTB44	zinc finger and BTB domain containing 44	11	-129601783	BC030580	29068	11q24.3	Hs.719099	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
224788_at	-0.363	6.984	-2.609	1.957e-02	0.279	-3.286	ARF6	ADP-ribosylation factor 6	14	49429485	AV700721	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
208674_x_at	-0.424	7.250	-2.609	1.957e-02	0.279	-3.286	DDOST	dolichyl-diphosphooligosaccharide-protein glycosyltransferase	1	-20850846	BC002594	1650	1p36.1	Hs.523145	12	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum microsome protein amino acid terminal N-glycosylation oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine response to cytokine stimulus T cell activation	N-Glycan biosynthesis Metabolic pathways
237679_at	0.224	4.044	2.609	1.958e-02	0.279	-3.286	TRIM66	tripartite motif-containing 66	11	-8590161	AI632106	9866	11p15.4	Hs.130836	4	protein binding intracellular nucleus zinc ion binding chromocenter transcription repressor activity protein homodimerization activity negative regulation of transcription, DNA-dependent metal ion binding
204963_at	0.545	9.720	2.608	1.959e-02	0.279	-3.287	SSPN	sarcospan (Kras oncogene-associated gene)	12	26239535, 26239772	AL136756	8082	12p11.2	Hs.183428	26	integral to plasma membrane muscle contraction cell adhesion dystrophin-associated glycoprotein complex cell junction transport vesicle sarcolemma synapse postsynaptic membrane
234519_at	0.295	5.249	2.608	1.962e-02	0.279	-3.288	NOBOX	NOBOX oogenesis homeobox	7	-143726971	AC004534	135935	7q35	Hs.558628	9	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development cell differentiation sequence-specific DNA binding oogenesis
1557347_at	0.222	5.498	2.607	1.965e-02	0.279	-3.289	MCPH1	microcephalin 1	8	6251528	N21605	79648	8p23.1	Hs.709634	32	intracellular centrosome
228578_at	-0.376	5.791	-2.607	1.965e-02	0.279	-3.290	RBM45	RNA binding motif protein 45	2	178685427	AI471723	129831	2q31.2	Hs.377257	3	nucleotide binding RNA binding nucleus cytoplasm multicellular organismal development nervous system development cell differentiation
218628_at	-0.499	8.227	-2.607	1.966e-02	0.279	-3.290	CCDC53	coiled-coil domain containing 53	12	-100930847	NM_016053	51019	12q23.2	Hs.405692	9	molecular_function protein binding cellular_component biological_process
216840_s_at	-0.510	6.806	-2.607	1.966e-02	0.279	-3.290	LAMA2	laminin, alpha 2	6	129245978	AK026829	3908	6q22-q23	Hs.200841	40	receptor binding structural molecule activity extracellular region basal lamina laminin-1 complex muscle organ development regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission, cholinergic sarcolemma regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212005_at	-0.347	7.229	-2.606	1.968e-02	0.279	-3.291	C1orf144	chromosome 1 open reading frame 144	1	16566169	AL582808	26099	1p36.13	Hs.252967	2
209422_at	-0.669	7.978	-2.606	1.969e-02	0.279	-3.291	PHF20	PHD finger protein 20	20	33823336	AL109965	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212409_s_at	-0.671	5.992	-2.606	1.969e-02	0.279	-3.291	TOR1AIP1	torsin A interacting protein 1	1	178118042	AK021613	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
222351_at	0.342	5.257	2.605	1.971e-02	0.279	-3.292	PPP2R1B	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	11	-111113814, -111102841	AW009884	5519	11q23.2	Hs.584790	34	antigen binding protein binding protein heterodimerization activity	Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression
1570115_at	-0.300	2.172	-2.605	1.971e-02	0.279	-3.292	PP12708	hypothetical LOC100130609	7		AF318327	100130609	7q34	Hs.684470
210837_s_at	-0.362	2.675	-2.605	1.972e-02	0.279	-3.293	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	AF012074	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
214789_x_at	-0.349	7.334	-2.605	1.973e-02	0.279	-3.293	SFRS2B	splicing factor, arginine/serine-rich 2B	11	94439703	AA524274	10929	11q22	Hs.476680 Hs.713908	6	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
203375_s_at	-0.394	7.546	-2.604	1.977e-02	0.280	-3.295	TPP2	tripeptidyl peptidase II	13	102047286	NM_003291	7174	13q32-q33	Hs.432424	23	aminopeptidase activity serine-type endopeptidase activity cytoplasm proteolysis peptidase activity tripeptidyl-peptidase activity
204943_at	0.309	5.669	2.604	1.977e-02	0.280	-3.295	ADAM12	ADAM metallopeptidase domain 12	10	-127719902, -127692894	NM_021641	8038	10q26.3	Hs.594537	59	metalloendopeptidase activity protein binding extracellular region plasma membrane proteolysis cell adhesion myoblast fusion peptidase activity zinc ion binding integral to membrane SH3 domain binding metal ion binding
221023_s_at	0.219	6.310	2.604	1.978e-02	0.280	-3.295	KCNH6	potassium voltage-gated channel, subfamily H (eag-related), member 6	17	58954426, 58954426	NM_030779	81033	17q23.3	Hs.591177	6	voltage-gated ion channel activity voltage-gated potassium channel activity regulation of transcription, DNA-dependent ion transport potassium ion transport signal transduction membrane integral to membrane potassium ion binding
206890_at	0.280	4.539	2.604	1.978e-02	0.280	-3.295	IL12RB1	interleukin 12 receptor, beta 1	19	-18042371, -18031370	NM_005535	3594	19p13.1	Hs.567294	51	cytokine receptor activity integral to plasma membrane cell surface receptor linked signal transduction positive regulation of cell proliferation membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
201011_at	-0.313	7.229	-2.604	1.979e-02	0.280	-3.296	RPN1	ribophorin I	3	-129821502	NM_002950	6184	3q21.3	Hs.518244 Hs.603636	19	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum protein amino acid glycosylation oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine rough endoplasmic reticulum membrane melanosome	N-Glycan biosynthesis Metabolic pathways
227358_at	0.368	5.645	2.603	1.980e-02	0.280	-3.296	ZBTB46	zinc finger and BTB domain containing 46	20	-61846321	Z39566	140685	20q13.33	Hs.585028	5	nucleic acid binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
217359_s_at	-0.669	3.700	-2.603	1.981e-02	0.280	-3.297	NCAM1	neural cell adhesion molecule 1	11	112337204, 112337204	M22094	4684	11q23.1	Hs.503878	120	protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane	Cell adhesion molecules (CAMs) Prion diseases
202165_at	-0.876	7.556	-2.603	1.981e-02	0.280	-3.297	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	3	-196722511	BF966540	5504	3q29	Hs.535731 Hs.706920	22	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy regulation of signal transduction regulation of phosphoprotein phosphatase activity
212367_at	-0.399	7.311	-2.603	1.981e-02	0.280	-3.297	FEM1B	fem-1 homolog b (C. elegans)	15	66357194	AI799061	10116	15q22	Hs.362733	9	ubiquitin-protein ligase activity death receptor binding death receptor binding cellular_component cytoplasm induction of apoptosis modification-dependent protein catabolic process regulation of apoptosis regulation of ubiquitin-protein ligase activity
202261_at	-0.496	8.273	-2.603	1.982e-02	0.280	-3.297	VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	1	-149415557	NM_005997	6944	1q21	Hs.2430	10	negative regulation of transcription from RNA polymerase II promoter transcription factor activity RNA polymerase II transcription factor activity nucleus chromatin modification protein complex regulation of transcription
211799_x_at	0.418	8.293	2.603	1.982e-02	0.280	-3.297	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	U62824	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
201628_s_at	-0.346	9.819	-2.603	1.982e-02	0.280	-3.297	RRAGA	Ras-related GTP binding A	9	19039371	NM_006570	10670	9p22.1	Hs.432330	10	nucleotide binding GTP binding nucleus cytoplasm Golgi apparatus apoptosis cell death virus-host interaction protein homodimerization activity interspecies interaction between organisms positive regulation of cytolysis protein heterodimerization activity phosphoprotein binding
203223_at	-0.976	4.860	-2.602	1.986e-02	0.280	-3.299	RABEP1	rabaptin, RAB GTPase binding effector protein 1	17	5126281	NM_004703	9135	17p13.2	Hs.584784 Hs.592121	19	GTPase activator activity protein binding cytoplasm early endosome endocytosis apoptosis membrane fusion growth factor activity protein transport recycling endosome	Endocytosis
206981_at	-0.491	7.705	-2.601	1.987e-02	0.280	-3.300	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	17	-59369645	NM_000334	6329	17q23-q25.3	Hs.46038	65	voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport muscle contraction membrane sodium ion binding
201799_s_at	-0.441	6.906	-2.601	1.988e-02	0.280	-3.300	OSBP	oxysterol binding protein	11	-59098446	AI927993	5007	11q12-q13	Hs.597091	13	cytoplasm Golgi apparatus lipid transport oxysterol binding steroid metabolic process membrane
202457_s_at	-0.656	9.104	-2.601	1.989e-02	0.280	-3.300	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	AA911231	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
238798_at	-0.512	4.930	-2.601	1.989e-02	0.280	-3.300	TAPT1	transmembrane anterior posterior transformation 1	4	-15771225	AA811306	202018	4p15.32	Hs.479223	5	receptor activity multicellular organismal development membrane integral to membrane
219799_s_at	0.361	4.808	2.601	1.990e-02	0.280	-3.301	DHRS9	dehydrogenase/reductase (SDR family) member 9	2	169629544, 169631790, 169637330, 169645862	NM_005771	10170	2q31.1	Hs.179608	11	alcohol dehydrogenase (NAD) activity alcohol dehydrogenase (NAD) activity retinol dehydrogenase activity retinol dehydrogenase activity binding endoplasmic reticulum endoplasmic reticulum membrane microsome microsome androgen metabolic process membrane oxidoreductase activity racemase and epimerase activity integral to endoplasmic reticulum membrane integral to endoplasmic reticulum membrane epithelial cell differentiation progesterone metabolic process retinol metabolic process 9-cis-retinoic acid biosynthetic process 9-cis-retinoic acid biosynthetic process 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity oxidation reduction	Retinol metabolism Metabolic pathways
202565_s_at	-0.443	11.809	-2.601	1.991e-02	0.280	-3.301	SVIL	supervillin	10	-29786282, -29786282	NM_003174	6840	10p11.2	Hs.499209	23	podosome calcium ion binding nucleus cytoplasm plasma membrane cytoskeleton organization skeletal muscle tissue development cell projection costamere actin filament binding
210373_at	0.297	5.954	2.599	1.996e-02	0.281	-3.304	TUSC4	tumor suppressor candidate 4	3	-50359922	AF040708	10641	3p21.3	Hs.437083	11	protein kinase activity protein binding negative regulation of kinase activity
213320_at	-0.518	5.994	-2.599	1.997e-02	0.281	-3.304	PRMT3	protein arginine methyltransferase 3	11	20365651	AL551971	10196	11p15.1	Hs.152337	10	protein binding intracellular cytoplasm cytosol ribosome protein amino acid methylation metabolic process methyltransferase activity zinc ion binding protein-arginine N-methyltransferase activity transferase activity metal ion binding
209047_at	0.490	8.788	2.598	2.003e-02	0.281	-3.307	AQP1	aquaporin 1 (Colton blood group)	7	30917992	AL518391	358	7p14	Hs.76152	100	transporter activity protein binding integral to plasma membrane transport water transport excretion water channel activity carbon dioxide transport ammonium transport membrane basolateral plasma membrane apical plasma membrane ammonia transporter activity
223305_at	0.292	5.925	2.596	2.008e-02	0.282	-3.309	TMEM216	transmembrane protein 216	11	60916440	AF151078	51259	11q13.1	Hs.26745	3	membrane integral to membrane
210610_at	0.265	5.710	2.596	2.008e-02	0.282	-3.309	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	M69176	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
232067_at	0.399	3.182	2.596	2.009e-02	0.282	-3.309	C6orf168	chromosome 6 open reading frame 168	6	-99827513	BC004869	84553	6q16.2	Hs.573245	5	mitochondrial outer membrane protein targeting to mitochondrion
213887_s_at	-0.360	8.572	-2.596	2.010e-02	0.282	-3.310	POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	19	-1037577	AI554759	5434	19p13.3	Hs.24301	91	nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter interspecies interaction between organisms	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
242528_at	0.256	3.103	2.596	2.010e-02	0.282	-3.310	LOC285943	hypothetical protein LOC285943	7		AI473887	285943	7p15.2	Hs.714774	1
227250_at	-0.761	6.666	-2.596	2.010e-02	0.282	-3.310	KREMEN1	kringle containing transmembrane protein 1	22	27799065, 27799105	BF221745	83999	22q12.1	Hs.229335	11	molecular_function membrane fraction cell communication membrane integral to membrane Wnt receptor signaling pathway
227777_at	-0.527	6.772	-2.596	2.011e-02	0.282	-3.310	C10orf18	chromosome 10 open reading frame 18	10	5766806	BF223040	54906	10p15.1	Hs.699500	4
219572_at	0.284	5.622	2.595	2.011e-02	0.282	-3.310	CADPS2	Ca++-dependent secretion activator 2	7	-121745713	NM_017954	93664	7q31.3	Hs.708214	12	calcium ion binding exocytosis lipid binding protein transport membrane cell junction cytoplasmic vesicle synapse
1553587_a_at	-0.529	7.607	-2.595	2.012e-02	0.282	-3.311	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	2	75039282	NM_019896	56655	2p12	Hs.469060	5	DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
1558954_at	0.315	5.816	2.595	2.013e-02	0.282	-3.311	SNORA78	small nucleolar RNA, H/ACA box 78	16	1955185	BC028232	677844	16p13.3	Hs.707294	2
37950_at	-0.431	7.856	-2.595	2.013e-02	0.282	-3.311	PREP	prolyl endopeptidase	6	-105832198	X74496	5550	6q22	Hs.436564	26	serine-type endopeptidase activity cytoplasm proteolysis peptidase activity
221526_x_at	-0.492	7.257	-2.595	2.014e-02	0.282	-3.311	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AW452651	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
229585_at	0.259	3.407	2.595	2.014e-02	0.282	-3.312	ADAMTSL1	ADAMTS-like 1	9	18464103, 18464103	AI803088	92949	9p22.2-p22.1	Hs.522019	10	extracellular region proteinaceous extracellular matrix peptidase activity metallopeptidase activity zinc ion binding
1553997_a_at	0.299	4.896	2.595	2.015e-02	0.282	-3.312	ASPHD1	aspartate beta-hydroxylase domain containing 1	16	29819647	BC034275	253982	16p11.2	Hs.655761	4	peptide-aspartate beta-dioxygenase activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane oxidation reduction
243582_at	-1.092	6.632	-2.594	2.016e-02	0.282	-3.312	SH3RF2	SH3 domain containing ring finger 2	5	145296318	AW082633	153769	5q32	Hs.443728	4	protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
204964_s_at	0.771	8.973	2.594	2.016e-02	0.282	-3.312	SSPN	sarcospan (Kras oncogene-associated gene)	12	26239535, 26239772	NM_005086	8082	12p11.2	Hs.183428	26	integral to plasma membrane muscle contraction cell adhesion dystrophin-associated glycoprotein complex cell junction transport vesicle sarcolemma synapse postsynaptic membrane
221732_at	0.340	7.107	2.594	2.016e-02	0.282	-3.312	CANT1	calcium activated nucleotidase 1	17	-74499392	AK026161	124583	17q25.3	Hs.8859	13	signal transducer activity calcium ion binding endoplasmic reticulum Golgi apparatus membrane integral to membrane hydrolase activity nucleoside-diphosphatase activity positive regulation of I-kappaB kinase/NF-kappaB cascade	Purine metabolism Pyrimidine metabolism
209522_s_at	0.493	9.483	2.594	2.017e-02	0.282	-3.313	CRAT	carnitine acetyltransferase	9	-130896895, -130896893	BC000723	1384	9q34.1	Hs.12068	10	carnitine O-acetyltransferase activity mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum lipid metabolic process fatty acid metabolic process transport acyltransferase activity energy derivation by oxidation of organic compounds membrane transferase activity
215880_at	-0.274	4.811	-2.594	2.017e-02	0.282	-3.313	NAGLU	N-acetylglucosaminidase, alpha-	17	37941476	AI364950	4669	17q21	Hs.50727	21	alpha-N-acetylglucosaminidase activity lysosome nervous system development metabolic process hydrolase activity, acting on glycosyl bonds glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
201784_s_at	-0.237	9.168	-2.594	2.018e-02	0.282	-3.313	C11orf58	chromosome 11 open reading frame 58	11	16716723	NM_014267	10944	11p15.1	Hs.719128	8	molecular_function cellular_component biological_process
201088_at	-0.759	7.145	-2.593	2.020e-02	0.282	-3.314	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	17	63462309, -1713110	NM_002266	3838	17q24.2	Hs.594238	125	regulation of DNA recombination M phase specific microtubule process G2 phase of mitotic cell cycle protein binding nucleus nuclear pore nucleoplasm cytoplasm DNA metabolic process NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
214730_s_at	-0.561	7.467	-2.593	2.020e-02	0.282	-3.314	GLG1	golgi apparatus protein 1	16	-73038828	AK025457	2734	16q22.3	Hs.109731	17	Golgi membrane receptor binding Golgi apparatus membrane integral to membrane	Cell adhesion molecules (CAMs)
211058_x_at	-0.599	10.584	-2.593	2.023e-02	0.282	-3.315	TUBA1B	tubulin, alpha 1b	12	-47807832	BC006379	10376	12q13.12	Hs.524390 Hs.719075	42	nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
240444_x_at	-0.224	4.924	-2.592	2.023e-02	0.282	-3.316	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	AA868722	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
222942_s_at	-0.696	5.655	-2.592	2.024e-02	0.282	-3.316	TIAM2	T-cell lymphoma invasion and metastasis 2	6	155453114, 155579788	AI094945	26230	6q25.2	Hs.586279	5	receptor signaling protein activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm intracellular signaling cascade lamellipodium filopodium growth cone regulation of Rho protein signal transduction	Chemokine signaling pathway Regulation of actin cytoskeleton
62987_r_at	0.276	8.982	2.592	2.025e-02	0.282	-3.317	CACNG4	calcium channel, voltage-dependent, gamma subunit 4	17	62391474	AI675178	27092	17q24	Hs.514423	9	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane integral to plasma membrane ion transport calcium ion transport transmission of nerve impulse	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212017_at	-0.283	8.302	-2.592	2.026e-02	0.282	-3.317	FAM168B	family with sequence similarity 168, member B	2	-131521918	BF677404	130074	2q21.1	Hs.534679	2
228095_at	-0.388	6.351	-2.592	2.026e-02	0.282	-3.317	PHF14	PHD finger protein 14	7	10980040, 10980040	AA608749	9678	7p21.3	Hs.655688	7	protein binding zinc ion binding metal ion binding
1553262_a_at	0.282	6.284	2.591	2.027e-02	0.282	-3.317	UTS2R	urotensin 2 receptor	17	77925489	NM_018949	2837	17q25.3	Hs.192720	21	urotensin II receptor activity receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway blood circulation integral to membrane	Neuroactive ligand-receptor interaction
219872_at	0.290	2.966	2.591	2.027e-02	0.282	-3.317	C4orf18	chromosome 4 open reading frame 18	4	-159265181, -159265181	NM_016613	51313	4q32.1	Hs.567498	9	Golgi apparatus membrane integral to membrane
213271_s_at	-0.329	6.951	-2.591	2.028e-02	0.282	-3.318	DOPEY1	dopey family member 1	6	83834103	AB029040	23033	6q15	Hs.520246 Hs.708998	6	protein transport
224415_s_at	0.379	9.434	2.591	2.028e-02	0.282	-3.318	HINT2	histidine triad nucleotide binding protein 2	9	-35802956	AF356515	84681	9p13.3	Hs.70573	6	extracellular region mitochondrion hydrolase activity
1558703_at	0.393	5.409	2.591	2.029e-02	0.282	-3.318	SLC46A1	solute carrier family 46 (folate transporter), member 1	17	-23745787	AL832613	113235	17q11.2	Hs.446689	22	folic acid binding cytoplasm plasma membrane transport folic acid transporter activity folic acid transport integral to membrane apical plasma membrane
202519_at	-0.449	9.261	-2.591	2.029e-02	0.282	-3.318	MLXIP	MLX interacting protein	12	121001142	NM_014938	22877	12q24.31	Hs.437153	7	DNA binding nucleus cytoplasm mitochondrion mitochondrial outer membrane membrane transcription regulator activity regulation of transcription
200912_s_at	-0.312	12.291	-2.591	2.029e-02	0.282	-3.318	EIF4A2	eukaryotic translation initiation factor 4A, isoform 2	3	187984054	NM_001967	1974	3q28	Hs.518475 Hs.599481	15	nucleotide binding RNA binding translation initiation factor activity helicase activity protein binding ATP binding cytosol translation regulation of translational initiation ATP-dependent helicase activity eukaryotic translation initiation factor 4F complex hydrolase activity interspecies interaction between organisms
215705_at	0.332	5.818	2.591	2.031e-02	0.282	-3.319	PPP5C	protein phosphatase 5, catalytic subunit	19	51542133	BC000750	5536	19q13.3	Hs.654604	39	protein serine/threonine phosphatase activity signal transducer activity iron ion binding protein binding nucleus cytoplasm transcription protein amino acid dephosphorylation mitosis hydrolase activity manganese ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway
215022_x_at	-0.457	3.269	-2.590	2.032e-02	0.282	-3.319	ZNF33B	zinc finger protein 33B	10	-42404560	BG429214	7582	10q11.2	Hs.499453	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222826_at	-0.542	6.780	-2.590	2.034e-02	0.282	-3.320	PLDN	pallidin homolog (mouse)	15	43666708	BC004819	26258	15q21.1	Hs.719102	17	cellular_component cytoplasm endosome membrane fusion blood coagulation membrane synaptic vesicle docking during exocytosis melanocyte differentiation syntaxin-13 binding positive regulation of natural killer cell activation secretion of lysosomal enzymes identical protein binding pigmentation
205741_s_at	0.392	9.024	2.589	2.036e-02	0.282	-3.321	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	NM_001392	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
1555864_s_at	0.300	10.969	2.589	2.037e-02	0.282	-3.321	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	X	19271931	AW057819	5160	Xp22.2-p22.1	Hs.530331	54	pyruvate dehydrogenase (acetyl-transferring) activity protein binding mitochondrion mitochondrial matrix glycolysis oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
216306_x_at	-0.374	6.896	-2.588	2.040e-02	0.283	-3.323	PTBP1	polypyrimidine tract binding protein 1	19	748391	X62006	5725	19p13.3	Hs.172550	65	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus poly-pyrimidine tract binding RNA splicing heterogeneous nuclear ribonucleoprotein complex
1569737_a_at	0.305	4.489	2.588	2.040e-02	0.283	-3.323	CASKIN1	CASK interacting protein 1	16	-2167184	BC042011	57524	16p13.3	Hs.643537	3	protein binding cytoplasm signal transduction
202479_s_at	-0.482	5.774	-2.588	2.041e-02	0.283	-3.324	TRIB2	tribbles homolog 2 (Drosophila)	2	12774448, 12774448	BC002637	28951	2p24.3	Hs.467751	16	nucleotide binding protein kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoskeleton protein amino acid phosphorylation regulation of MAP kinase activity
233496_s_at	-0.464	10.678	-2.588	2.042e-02	0.283	-3.324	CFL2	cofilin 2 (muscle)	14	-34249338, -34249338, -34249338	AV726166	1073	14q12	Hs.180141	20	actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
1554631_at	0.295	5.793	2.588	2.043e-02	0.283	-3.324	ATM	ataxia telangiectasia mutated	11	107598768, 107663328	BC007023	472	11q22-q23	Hs.367437	504	nucleotide binding DNA binding protein serine/threonine kinase activity ATP binding nucleus nucleoplasm DNA repair response to DNA damage stimulus cell cycle mitotic cell cycle spindle assembly checkpoint reciprocal meiotic recombination signal transduction cell death response to ionizing radiation 1-phosphatidylinositol-3-kinase activity transferase activity cytoplasmic vesicle protein N-terminus binding	Cell cycle p53 signaling pathway Apoptosis
219867_at	0.477	5.047	2.588	2.043e-02	0.283	-3.324	CHODL	chondrolectin	21	18539020	NM_024944	140578	21q11.2	Hs.283725	9	binding sugar binding hyaluronic acid binding muscle organ development membrane integral to membrane perinuclear region of cytoplasm
207309_at	0.361	5.567	2.586	2.049e-02	0.283	-3.327	NOS1	nitric oxide synthase 1 (neuronal)	12	-116135361	NM_000620	4842	12q24.2-q24.31	Hs.654410	188	response to hypoxia photoreceptor inner segment nitric-oxide synthase activity calmodulin binding cytoplasm cytoskeleton arginine catabolic process nitric oxide biosynthetic process myoblast fusion electron carrier activity response to heat FMN binding negative regulation of calcium ion transport into cytosol oxidoreductase activity sarcoplasmic reticulum heme binding multicellular organismal response to stress tetrahydrobiopterin binding arginine binding neurotransmitter biosynthetic process sarcolemma cell projection dendritic spine positive regulation of vasodilation positive regulation of vasodilation cadmium ion binding metal ion binding perinuclear region of cytoplasm FAD binding NADP or NADPH binding oxidation reduction regulation of cardiac muscle contraction	Arginine and proline metabolism Metabolic pathways Calcium signaling pathway Long-term depression Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer Small cell lung cancer
210988_s_at	-0.486	5.587	-2.586	2.051e-02	0.284	-3.328	PRUNE	prune homolog (Drosophila)	1	149247596	AF123538	58497	1q21	Hs.78524	8	inorganic diphosphatase activity protein binding nucleus cytoplasm focal adhesion hydrolase activity cell junction manganese ion binding metal ion binding	Purine metabolism
201712_s_at	-0.401	6.737	-2.585	2.055e-02	0.284	-3.329	RANBP2	RAN binding protein 2	2	108702368	NM_006267	5903	2q12.3	Hs.199561 Hs.715056	61	peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport
214118_x_at	-0.300	8.593	-2.585	2.055e-02	0.284	-3.329	PCM1	pericentriolar material 1	8	17824645	AI205598	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
216008_s_at	-0.345	7.424	-2.585	2.055e-02	0.284	-3.330	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	AV694434	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
205910_s_at	0.305	2.909	2.584	2.057e-02	0.284	-3.330	CEL	carboxyl ester lipase (bile salt-stimulated lipase)	9	134927185	NM_001807	1056	9q34.3	Hs.533258	51	sterol esterase activity sterol esterase activity triacylglycerol lipase activity extracellular region cytoplasm triglyceride metabolic process cholesterol catabolic process cholesterol catabolic process heparin binding fatty acid catabolic process lipid catabolic process hydrolase activity protein amino acid esterification pancreatic juice secretion intestinal cholesterol absorption intestinal lipid catabolic process acylglycerol lipase activity	Steroid biosynthesis Glycerolipid metabolism Metabolic pathways
222701_s_at	0.378	7.226	2.584	2.057e-02	0.284	-3.330	CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7	8	57286868	AA570393	79145	8q12.1	Hs.436913	9
209217_s_at	-0.322	7.422	-2.584	2.059e-02	0.284	-3.331	WDR45	WD repeat domain 45	X	-48819035, -48819035	BC000464	11152	Xp11.23	Hs.632807	8
244783_at	-0.292	2.576	-2.584	2.059e-02	0.284	-3.331	YAF2	YY1 associated factor 2	12	-40837173	R56794	10138	12q12	Hs.708084	9	transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus zinc ion binding negative regulation of transcription positive regulation of transcription metal ion binding
221058_s_at	0.324	5.747	2.583	2.061e-02	0.284	-3.332	CKLF	chemokine-like factor	16	65143966, 65143972	NM_016326	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
1555567_s_at	-0.557	7.832	-2.583	2.062e-02	0.284	-3.332	LMOD3	leiomodin 3 (fetal)	3	-69238728	BC039202	56203	3p14.1	Hs.350621	9	tropomyosin binding cytoplasm cytoskeleton
230430_at	0.223	5.452	2.582	2.064e-02	0.284	-3.334	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	9	-139062373	AW134837	954	9q34	Hs.123036	14	magnesium ion binding calcium ion binding membrane integral to membrane hydrolase activity	Purine metabolism
209944_at	-0.287	7.678	-2.582	2.066e-02	0.284	-3.334	ZNF410	zinc finger protein 410	14	73423338	BC000330	57862	14q24.3	Hs.270869	9	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
53720_at	0.382	6.198	2.582	2.066e-02	0.284	-3.334	C19orf66	chromosome 19 open reading frame 66	19	10057805	AI862559	55337	19p13.2	Hs.655613	2
1561928_s_at	0.280	5.156	2.581	2.069e-02	0.285	-3.335	C3orf16	chromosome 3 open reading frame 16	3	-150961581	AK027233	389161	3q25.1	Hs.665988	3
204969_s_at	-0.607	5.074	-2.581	2.069e-02	0.285	-3.336	RDX	radixin	11	-109605375	NM_002906	5962	11q23	Hs.263671 Hs.592679	46	ruffle actin binding cytoplasm cytoskeleton plasma membrane extrinsic to membrane lamellipodium microvillus assembly filopodium stereocilium apical protein localization apical part of cell actin filament capping	Regulation of actin cytoskeleton
231416_at	0.286	5.398	2.581	2.071e-02	0.285	-3.337	DHDH	dihydrodiol dehydrogenase (dimeric)	19	54128750	NM_014475	27294	19q13.3	Hs.631555	6	binding carbohydrate metabolic process NAD(P) transhydrogenase activity electron carrier activity oxidoreductase activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity D-xylose 1-dehydrogenase (NADP+) activity oxidation reduction	Metabolism of xenobiotics by cytochrome P450
206611_at	0.352	6.200	2.580	2.073e-02	0.285	-3.337	C2orf27A	chromosome 2 open reading frame 27A	2	132196533	NM_013310	29798	2q21.1-q21.2	Hs.635289 Hs.655680	5
207040_s_at	-0.422	10.356	-2.580	2.075e-02	0.285	-3.338	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22	-39550546	NM_003932	6767	22q13.2	Hs.712713	29	binding cytoplasm protein folding protein binding, bridging
223331_s_at	-0.307	6.417	-2.580	2.075e-02	0.285	-3.338	DDX20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20	1	112099776	AF106019	11218	1p21.1-p13.2	Hs.591405	30	negative regulation of transcription from RNA polymerase II promoter nucleotide binding assembly of spliceosomal tri-snRNP DNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus nucleoplasm spliceosomal complex cytoplasm cytosol cytoskeleton mRNA processing induction of apoptosis RNA splicing Cajal body transcription repressor activity hydrolase activity transcriptional repressor complex
232124_at	0.352	3.430	2.580	2.076e-02	0.285	-3.338	LOC729085	hypothetical protein LOC729085	3	42995762	AL117530	729085	3p22.1	Hs.146346	2
206082_at	0.566	5.129	2.579	2.078e-02	0.285	-3.339	HCP5	HLA complex P5	6	31538935, 2877117	NM_006674	10866	6p21.3	Hs.654480	12	defense response
212795_at	-0.771	7.536	-2.579	2.080e-02	0.285	-3.340	KIAA1033	KIAA1033	12	104025621	AL137753	23325	12q24.11	Hs.12144	4
1554086_at	0.269	4.579	2.579	2.080e-02	0.285	-3.340	TUBGCP3	tubulin, gamma complex associated protein 3	13	-112187328	BC007763	10426	13q34	Hs.224152	8	structural constituent of cytoskeleton protein binding cytoplasm centriole polar microtubule microtubule microtubule nucleation gamma-tubulin binding
219090_at	-0.982	7.810	-2.578	2.080e-02	0.285	-3.340	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	20	19141289	NM_020689	57419	20p13	Hs.654790	2	calcium ion binding ion transport potassium ion transport sodium ion transport calcium ion transport calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral to membrane potassium ion binding sodium ion binding
230264_s_at	-0.493	9.723	-2.578	2.083e-02	0.285	-3.341	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	X	-15753849	AA551090	8905	Xp22.2	Hs.653504 Hs.656471	21	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
235129_at	0.534	8.734	2.578	2.083e-02	0.285	-3.342	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	12	-53259290	BF510098	5502	12q13.2	Hs.505662	9	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process signal transduction	Long-term potentiation
222036_s_at	0.509	6.817	2.577	2.086e-02	0.286	-3.343	MCM4	minichromosome maintenance complex component 4	8	49036046	AI859865	4173	8q11.2	Hs.460184	47	nucleotide binding DNA binding DNA helicase activity single-stranded DNA binding protein binding ATP binding nucleus nucleoplasm nucleolus DNA replication DNA replication DNA unwinding during replication DNA replication initiation nucleoside-triphosphatase activity regulation of transcription	DNA replication Cell cycle
225026_at	-0.413	4.401	-2.577	2.086e-02	0.286	-3.343	CHD6	chromodomain helicase DNA binding protein 6	20	-39464583	BF572029	84181	20q12	Hs.371979	12	nucleotide binding chromatin DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly chromatin remodeling regulation of transcription, DNA-dependent nervous system development ATP-dependent helicase activity hydrolase activity
226994_at	-0.471	7.892	-2.577	2.087e-02	0.286	-3.343	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	16	-45546774	AW057513	10294	16q12.1	Hs.368078	15	protein folding zinc ion binding positive regulation of cell proliferation membrane heat shock protein binding metal ion binding unfolded protein binding
202972_s_at	-0.449	5.994	-2.577	2.088e-02	0.286	-3.344	FAM13A	family with sequence similarity 13, member A	4	-89866128, -89866128	AW450403	10144	4q22.1	Hs.97270	7
218909_at	-0.371	6.987	-2.576	2.089e-02	0.286	-3.344	RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1	1	211291210	NM_012424	26750	1q41	Hs.591416	10	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm early endosome protein amino acid phosphorylation signal transduction membrane transferase activity phosphoinositide binding
1554424_at	-0.634	4.846	-2.576	2.090e-02	0.286	-3.344	FIP1L1	FIP1 like 1 (S. cerevisiae)	4	53938576	BC017724	81608	4q12	Hs.624245	28	RNA binding nucleus mRNA processing
226143_at	0.440	7.538	2.576	2.091e-02	0.286	-3.345	RAI1	retinoic acid induced 1	17	17525511	BF984830	10743	17p11.2	Hs.655395	16	protein binding nucleus cytoplasm zinc ion binding metal ion binding
227277_at	-0.481	5.409	-2.576	2.091e-02	0.286	-3.345	MTDH	metadherin	8	98725582	BG530089	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
217800_s_at	-0.439	7.775	-2.576	2.091e-02	0.286	-3.345	NDFIP1	Nedd4 family interacting protein 1	5	141468507	NM_030571	80762	5q31.3	Hs.653510 Hs.9788	11	signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport
209676_at	-0.432	3.430	-2.576	2.092e-02	0.286	-3.346	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	2	-188051550, -188037202	J03225	7035	2q32	Hs.516578	118	serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway	Complement and coagulation cascades
243971_x_at	0.495	4.723	2.576	2.092e-02	0.286	-3.346	LOC731789	hypothetical LOC731789	10	26972042	AL042865	731789	10p12.1	Hs.178186	1
204957_at	-0.476	6.275	-2.576	2.092e-02	0.286	-3.346	ORC5L	origin recognition complex, subunit 5-like (yeast)	7	-103595859, -103554023	NM_002553	5001	7q22.1	Hs.432948	28	nucleotide binding DNA replication origin binding ATP binding nucleus nucleoplasm DNA replication DNA replication DNA replication initiation identical protein binding	Cell cycle
224747_at	-0.843	7.213	-2.576	2.093e-02	0.286	-3.346	UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2	15	73922676, 73923439	AK000617	92912	15q24.2	Hs.23033	4	nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
208867_s_at	-0.619	6.506	-2.575	2.093e-02	0.286	-3.346	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	AF119911	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
207692_s_at	0.307	5.141	2.574	2.097e-02	0.286	-3.348	ACAN	aggrecan	15	87147677	NM_001135	176	15q26.1	Hs.2159 Hs.616395 Hs.711491	59	skeletal system development binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix proteolysis cell adhesion extracellular matrix structural constituent conferring compression resistance extracellular matrix organization
210127_at	0.339	4.139	2.574	2.100e-02	0.286	-3.349	RAB6B	RAB6B, member RAS oncogene family	3	-135025769	BC002510	51560	3q22.1	Hs.707804	10	nucleotide binding GTPase activity GTP binding Golgi apparatus retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane vesicle-mediated transport
209352_s_at	0.269	5.283	2.573	2.102e-02	0.286	-3.349	SIN3B	SIN3 homolog B, transcription regulator (yeast)	19	16801217	AB014600	23309	19p13.11	Hs.13999	22	protein binding nucleus regulation of transcription, DNA-dependent
224857_s_at	-0.342	7.320	-2.573	2.102e-02	0.286	-3.350	POLR1D	polymerase (RNA) I polypeptide D, 16kDa	13	27094002, 27094028	BE378670	51082	13q12.2	Hs.507584	15	DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm transcription protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
214954_at	-0.617	2.832	-2.573	2.104e-02	0.286	-3.351	SUSD5	sushi domain containing 5	3	-33166540	BF977837	26032	3p22.3	Hs.196647	2	binding hyaluronic acid binding cell adhesion membrane integral to membrane
227064_at	-0.439	9.157	-2.573	2.105e-02	0.286	-3.351	ANKRD40	ankyrin repeat domain 40	17	-46125550	AV712687	91369	17q21.33	Hs.463426	2
212398_at	-0.560	7.399	-2.573	2.105e-02	0.286	-3.351	RDX	radixin	11	-109605375	AI057093	5962	11q23	Hs.263671 Hs.592679	46	ruffle actin binding cytoplasm cytoskeleton plasma membrane extrinsic to membrane lamellipodium microvillus assembly filopodium stereocilium apical protein localization apical part of cell actin filament capping	Regulation of actin cytoskeleton
1562540_at	0.323	4.285	2.572	2.106e-02	0.286	-3.351	LOC339978	hypothetical protein LOC339978	4		BC043566	339978	4q12		1
41512_at	-0.543	6.164	-2.572	2.106e-02	0.286	-3.352	BRAP	BRCA1 associated protein	12	-110564332	AL042733	8315	12q24	Hs.530940	12	ubiquitin-protein ligase activity cytoplasm zinc ion binding negative regulation of signal transduction ligase activity modification-dependent protein catabolic process identical protein binding metal ion binding
1555216_a_at	0.358	4.941	2.572	2.107e-02	0.286	-3.352	LOC645722	hypothetical LOC645722	17		BC009278	645722	17q23.2
210162_s_at	-0.594	6.271	-2.572	2.108e-02	0.286	-3.352	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	18	75256759, 75256759, 75261313	U08015	4772	18q23	Hs.534074 Hs.701518	83	transcription factor activity FK506 binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter intracellular signaling cascade transcription activator activity	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
202850_at	-0.468	9.111	-2.572	2.108e-02	0.286	-3.352	ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	1	94656520, 94656520	NM_002858	5825	1p22-p21	Hs.700576	25	nucleotide binding protein binding ATP binding peroxisome peroxisomal membrane integral to peroxisomal membrane transport peroxisome organization peroxisomal long-chain fatty acid import membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters
220564_at	-0.293	4.495	-2.572	2.108e-02	0.286	-3.352	RNLS	renalase, FAD-dependent amine oxidase	10	-90033839, -90023600	NM_018363	55328	10q23.31	Hs.149849	10	monooxygenase activity extracellular region oxidation reduction
244565_at	0.248	4.642	2.572	2.109e-02	0.286	-3.353	HMX2	H6 family homeobox 2	10	124897627	AI685824	3167	10q25.2-q26.3	Hs.444756	3	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development nervous system development brain development positive regulation of cell proliferation cell differentiation inner ear morphogenesis sequence-specific DNA binding
201142_at	-0.377	7.518	-2.572	2.109e-02	0.286	-3.353	EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	14	66896786	AA577698	1965	14q23.3	Hs.151777	73	RNA binding translation initiation factor activity protein binding nucleus cytoplasm cytosol polysome eukaryotic translation initiation factor 2 complex eukaryotic translation initiation factor 2B complex regulation of translation regulation of translational initiation in response to stress
217196_s_at	-0.640	5.317	-2.571	2.112e-02	0.286	-3.354	CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1	1	198975308	AL110158	23271	1q32.1	Hs.23585	6
217613_at	0.340	3.194	2.571	2.114e-02	0.287	-3.355	TMEM144	transmembrane protein 144	4	159350850	AW173720	55314	4q32.1	Hs.718582	2	membrane integral to membrane
201829_at	-0.413	6.941	-2.570	2.114e-02	0.287	-3.355	NET1	neuroepithelial cell transforming 1	10	5444517, 5478545	AW263232	10276	10p15	Hs.25155	19	regulation of cell growth guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity cellular_component intracellular nucleus cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction
224874_at	-0.493	7.384	-2.570	2.115e-02	0.287	-3.355	POLR1D	polymerase (RNA) I polypeptide D, 16kDa	13	27094002, 27094028	N32181	51082	13q12.2	Hs.507584	15	DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm transcription protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
235426_at	0.287	4.629	2.569	2.119e-02	0.287	-3.357	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	AW293951	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
1554400_at	0.218	4.057	2.568	2.124e-02	0.288	-3.359	TCTE3	t-complex-associated-testis-expressed 3	6	-169882139	AF519569	6991	6q27	Hs.584808	3	membrane
239126_at	0.304	3.546	2.568	2.125e-02	0.288	-3.359	C19orf23	chromosome 19 open reading frame 23	19	-1218470	AA012950	148046	19p13.3	Hs.438829	2
1554352_s_at	-0.315	5.320	-2.567	2.127e-02	0.288	-3.360	DENND4A	DENN/MADD domain containing 4A	15	-63740012	BC041706	10260	15q22.31	Hs.654567	8	DNA binding protein binding nucleus regulation of transcription, DNA-dependent
206284_x_at	-0.360	8.518	-2.567	2.127e-02	0.288	-3.360	CLTB	clathrin, light chain (Lcb)	5	-175752061	NM_001834	1212	4q2-q3 5q35	Hs.484241	17	structural molecule activity calcium ion binding protein binding intracellular protein transport membrane vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle	Lysosome Endocytosis Huntington's disease
1556864_at	0.277	6.183	2.567	2.129e-02	0.288	-3.361	TCTN1	tectonic family member 1	12	109536262	BC030993	79600	12q24.11	Hs.211511 Hs.694390	5	extracellular region multicellular organismal development
1557729_at	0.295	5.142	2.567	2.129e-02	0.288	-3.361	LOC100131848	FP2025	10		AK097099	100131848	10q26.11	Hs.711375	1
223028_s_at	-0.358	6.899	-2.567	2.130e-02	0.288	-3.362	SNX9	sorting nexin 9	6	158164281	BC005022	51429	6q25.1-q26	Hs.191213	24	protein binding cell communication protein transport phosphoinositide binding
1568704_a_at	0.397	8.136	2.566	2.132e-02	0.288	-3.362	CHERP	calcium homeostasis endoplasmic reticulum protein	19	-16489699	BF511683	10523	19p13.1	Hs.631627	5	molecular_function RNA binding cellular_component intracellular cytoplasm endoplasmic reticulum RNA processing nervous system development biological_process perinuclear region of cytoplasm
223260_s_at	-0.524	5.083	-2.566	2.133e-02	0.288	-3.363	POLK	polymerase (DNA directed) kappa	5	74843412	AB027564	51426	5q13	Hs.715657	39	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity nucleus DNA replication DNA repair response to DNA damage stimulus zinc ion binding transferase activity nucleotidyltransferase activity
204297_at	-0.431	6.290	-2.566	2.133e-02	0.288	-3.363	PIK3C3	phosphoinositide-3-kinase, class 3	18	37789196	NM_002647	5289	18q12.3	Hs.464971	42	nucleotide binding inositol or phosphatidylinositol kinase activity protein kinase activity protein binding ATP binding cytosol phosphoinositide 3-kinase complex protein amino acid phosphorylation 1-phosphatidylinositol-3-kinase activity transferase activity manganese ion binding phosphoinositide phosphorylation phosphoinositide-mediated signaling	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system Regulation of autophagy
219824_at	0.267	5.833	2.566	2.134e-02	0.288	-3.363	SLC13A4	solute carrier family 13 (sodium/sulfate symporters), member 4	7	-135016526	NM_012450	26266	7q33	Hs.200022 Hs.490241	5	transporter activity integral to plasma membrane ion transport sodium ion transport sulfate transport symporter activity sodium:sulfate symporter activity membrane sodium ion binding
224793_s_at	-0.511	7.460	-2.565	2.135e-02	0.288	-3.364	TGFBR1	transforming growth factor, beta receptor 1	9	100907232, 100907232	AA604375	7046	9q22	Hs.494622	202	nucleotide binding activation of MAPKK activity magnesium ion binding in utero embryonic development kidney development protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity, type I type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding ATP binding signal transduction transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway heart development positive regulation of cell proliferation germ cell migration anterior/posterior pattern formation positive regulation of pathway-restricted SMAD protein phosphorylation integral to membrane transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation manganese ion binding collagen fibril organization positive regulation of cell growth positive regulation of survival gene product expression positive regulation of transcription SMAD binding protein heterodimerization activity thymus development neuron fate commitment embryonic cranial skeleton morphogenesis skeletal system morphogenesis artery morphogenesis cell motility transforming growth factor beta binding positive regulation of cell motion positive regulation of protein kinase B signaling cascade parathyroid gland development palate development pharyngeal system development positive regulation of SMAD protein nuclear translocation transforming growth factor beta receptor complex response to cholesterol	MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia
212797_at	-0.346	2.825	-2.565	2.136e-02	0.288	-3.364	SORT1	sortilin 1	1	-109653714	BE742268	6272	1p21.3-p13.1	Hs.485195 Hs.703487	47	ossification receptor activity nucleus lysosome early endosome endoplasmic reticulum microsome Golgi apparatus plasma membrane coated pit transport Golgi to endosome transport endocytosis neuropeptide signaling pathway multicellular organismal development endosome to lysosome transport induction of apoptosis by extracellular signals cell surface nerve growth factor receptor activity regulation of gene expression myotube differentiation integral to membrane cytoplasmic membrane-bounded vesicle vesicle organization enzyme binding clathrin-coated vesicle cell differentiation neurotensin receptor activity, non-G-protein coupled endosome transport via multivesicular body sorting pathway response to insulin stimulus negative regulation of apoptosis glucose import nerve growth factor receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity	Lysosome Neurotrophin signaling pathway
213009_s_at	-0.413	7.799	-2.565	2.136e-02	0.288	-3.364	TRIM37	tripartite motif-containing 37	17	-54430342, -54414781	AK022701	4591	17q23.2	Hs.579079 Hs.605697	23	protein binding intracellular cytoplasm peroxisome zinc ion binding metal ion binding	Ubiquitin mediated proteolysis
1555961_a_at	-0.286	11.509	-2.565	2.136e-02	0.288	-3.364	HINT1	histidine triad nucleotide binding protein 1	5	-130522773, -130522773	AK054976	3094	5q31.2	Hs.483305	26	protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity
229422_at	-0.631	6.298	-2.565	2.137e-02	0.288	-3.364	NRD1	nardilysin (N-arginine dibasic convertase)	1	-52027453	AA448346	4898	1p32.2-p32.1	Hs.584782	18	metalloendopeptidase activity protein binding cytosol proteolysis neuromuscular junction development peptidase activity zinc ion binding cell proliferation cell surface cell migration metal ion binding epidermal growth factor binding positive regulation of membrane protein ectodomain proteolysis regulation of endopeptidase activity
223547_at	-0.535	5.665	-2.565	2.138e-02	0.288	-3.365	JKAMP	JNK1/MAPK8-associated membrane protein	14	59020913	AL038769	51528	14q23.1	Hs.446850	12	plasma membrane integral to membrane
205747_at	0.349	3.620	2.565	2.139e-02	0.288	-3.365	CBLN1	cerebellin 1 precursor	16	-47869711	NM_004352	869	16q12.1	Hs.458423	8	protein binding extracellular region synaptic transmission nervous system development membrane cell junction protein homodimerization activity synapse
1553146_at	0.302	4.228	2.564	2.139e-02	0.288	-3.365	C3orf30	chromosome 3 open reading frame 30	3	120347686	NM_152539	152405	3q13.32	Hs.632574	1
221706_s_at	-0.305	7.094	-2.564	2.140e-02	0.288	-3.366	USE1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	19	17187154	BC006005	55850	19p13.11	Hs.16187	12	protein binding lysosome endoplasmic reticulum ER to Golgi vesicle-mediated transport lysosomal transport protein transport membrane integral to membrane vesicle-mediated transport protein catabolic process	SNARE interactions in vesicular transport
224303_x_at	-0.445	5.256	-2.564	2.140e-02	0.288	-3.366	NIN	ninein (GSK3B interacting protein)	14	-50263700, -50262296, -50262296, -50256230	AF223938	51199	14q22.1	Hs.310429	23	nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization
209577_at	0.251	6.605	2.563	2.145e-02	0.289	-3.368	PCYT2	phosphate cytidylyltransferase 2, ethanolamine	17	-77455383, -2421678	BC000351	5833	17q25.3	Hs.645248	8	ethanolamine-phosphate cytidylyltransferase activity cellular_component phospholipid biosynthetic process biosynthetic process transferase activity nucleotidyltransferase activity	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
221413_at	0.288	4.764	2.563	2.145e-02	0.289	-3.368	KCNAB3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	17	-7766751	NM_004732	9196	17p13.1	Hs.435074	6	voltage-gated ion channel activity voltage-gated potassium channel activity cytoplasm ion transport potassium ion transport potassium channel regulator activity integral to membrane oxidoreductase activity potassium ion binding oxidation reduction
204217_s_at	-0.546	8.193	-2.563	2.146e-02	0.289	-3.368	RTN2	reticulon 2	19	-50680389, -50680389, -50680389	NM_005619	6253	19q13.32	Hs.47517	10	signal transducer activity endoplasmic reticulum signal transduction membrane integral to membrane integral to endoplasmic reticulum membrane
221499_s_at	-0.331	6.816	-2.563	2.147e-02	0.289	-3.368	STX16	syntaxin 16	20	56659733, 56659733	AK026970	8675	20q13.32	Hs.307913	14	SNAP receptor activity cytoplasm microsome Golgi apparatus intracellular protein transport intra-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport SNARE complex retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
228266_s_at	0.385	4.389	2.562	2.149e-02	0.289	-3.369	HDGFRP3	hepatoma-derived growth factor, related protein 3	15	-81597819	BE703418	50810	15q25.2	Hs.513954	9	nucleus cytoplasm growth factor activity cell proliferation
200954_at	0.300	8.103	2.562	2.149e-02	0.289	-3.369	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	16	2503953	NM_001694	527	16p13.3	Hs.389107	23	protein binding vacuole ion transport ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting V-type ATPase, V0 domain interspecies interaction between organisms proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
219805_at	0.414	6.465	2.561	2.153e-02	0.289	-3.371	CXorf56	chromosome X open reading frame 56	X	-118557528	NM_022101	63932	Xq23	Hs.248572	3	protein binding
218977_s_at	0.404	5.319	2.560	2.158e-02	0.290	-3.373	TRNAU1AP	tRNA selenocysteine 1 associated protein 1	1	28752115	NM_017846	54952	1p35.3	Hs.533626	5	nucleotide binding selenocysteine incorporation RNA binding nucleus cytoplasm translation
208428_at	0.301	3.996	2.559	2.162e-02	0.290	-3.375	TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	6	-32901164, -32897587, -4174042, -4170466, -3979239, -3975663	NM_018833	6891	6p21.3	Hs.502	129	nucleotide binding homoaconitate hydratase activity transporter activity ATP binding nucleus endoplasmic reticulum endoplasmic reticulum lumen cytosol protein complex assembly intracellular protein transport immune response peptide transporter activity peptide antigen-transporting ATPase activity peptide transport membrane integral to membrane ATPase activity antigen processing and presentation of endogenous peptide antigen via MHC class I MHC class I protein binding phosphate binding peptide antigen binding ATPase activity, coupled to transmembrane movement of substances TAP complex interspecies interaction between organisms cytosol to ER transport tapasin binding protein heterodimerization activity	ABC transporters Antigen processing and presentation Primary immunodeficiency
211282_x_at	0.307	5.251	2.559	2.162e-02	0.290	-3.375	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	1	-6446757, -6443800	U94506	8718	1p36.2	Hs.462529	30	receptor activity tumor necrosis factor receptor activity protein binding extracellular region cytosol plasma membrane integral to plasma membrane cell surface receptor linked signal transduction induction of apoptosis by extracellular signals regulation of apoptosis	Cytokine-cytokine receptor interaction
215415_s_at	0.292	3.413	2.559	2.163e-02	0.290	-3.375	LYST	lysosomal trafficking regulator	1	-233890968	U70064	1130	1q42.1-q42.2	Hs.532411	23	protein binding cytoplasm protein transport microtubule cytoskeleton leukocyte chemotaxis melanosome organization endosome to lysosome transport via multivesicular body sorting pathway mast cell secretory granule organization natural killer cell mediated cytotoxicity defense response to bacterium defense response to protozoan pigmentation defense response to virus
219002_at	1.043	7.443	2.559	2.163e-02	0.290	-3.375	FASTKD1	FAST kinase domains 1	2	-170094508	NM_024622	79675	2q31	Hs.529276	6	protein kinase activity ATP binding apoptosis
219646_at	-0.557	6.572	-2.558	2.165e-02	0.290	-3.376	DEF8	differentially expressed in FDCP 8 homolog (mouse)	16	88542651, 88542683	NM_017702	54849	16q24.3	Hs.62771	4	protein binding intracellular signaling cascade zinc ion binding diacylglycerol binding metal ion binding
228023_x_at	-0.343	7.370	-2.558	2.166e-02	0.290	-3.376	AMY2B	amylase, alpha 2B (pancreatic)	1	103898844	AV699389	280	1p21	Hs.484588	19	alpha-amylase activity calcium ion binding extracellular region carbohydrate metabolic process digestion metabolic process hydrolase activity, acting on glycosyl bonds chloride ion binding	Starch and sucrose metabolism Metabolic pathways
208745_at	0.430	9.469	2.558	2.166e-02	0.290	-3.376	ATP5L	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G	11	117777313	AA917672	10632	11q23.3	Hs.486360	15	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) protein binding mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
222083_at	0.355	5.101	2.558	2.168e-02	0.290	-3.377	GLYAT	glycine-N-acyltransferase	11	-58234136, -58232805	AW024233	10249	11q12.1	Hs.145384	12	mitochondrion acyl-CoA metabolic process acyltransferase activity response to toxin transferase activity glycine N-acyltransferase activity
202829_s_at	-0.386	7.722	-2.558	2.169e-02	0.290	-3.378	VAMP7	vesicle-associated membrane protein 7	X, Y	154764140, 57623340	NM_005638	6845	Xq28 Yq12	Hs.24167	38	protein binding protein binding lysosomal membrane endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ER to Golgi vesicle-mediated transport vesicle fusion phagocytosis, engulfment endosome to lysosome transport protein transport membrane integral to membrane calcium ion-dependent exocytosis SNARE complex cytoplasmic vesicle late endosome membrane eosinophil degranulation neutrophil degranulation apical part of cell phagocytic vesicle	SNARE interactions in vesicular transport
224991_at	0.366	4.888	2.558	2.169e-02	0.290	-3.378	CMIP	c-Maf-inducing protein	16	80036275, 80086454	AI819630	80790	16q23	Hs.709248	7	nucleus cytoplasm
212373_at	-0.595	5.730	-2.558	2.169e-02	0.290	-3.378	FEM1B	fem-1 homolog b (C. elegans)	15	66357194	AW139179	10116	15q22	Hs.362733	9	ubiquitin-protein ligase activity death receptor binding death receptor binding cellular_component cytoplasm induction of apoptosis modification-dependent protein catabolic process regulation of apoptosis regulation of ubiquitin-protein ligase activity
202568_s_at	-0.429	7.023	-2.557	2.170e-02	0.290	-3.378	MARK3	MAP/microtubule affinity-regulating kinase 3	14	102921453	AI745639	4140	14q32.3	Hs.35828	24	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
225876_at	0.509	5.801	2.557	2.170e-02	0.290	-3.378	NIPAL3	NIPA-like domain containing 3	1	24614831	T84558	57185	1p36.12-p35.1	Hs.523442	6	membrane integral to membrane
201795_at	-0.359	7.021	-2.557	2.170e-02	0.290	-3.378	LBR	lamin B receptor	1	-223655826, -223655826	NM_002296	3930	1q42.1	Hs.435166	33	DNA binding receptor activity lamin binding nucleus nuclear envelope integral to nuclear inner membrane membrane integral to membrane delta14-sterol reductase activity
214258_x_at	-0.332	6.675	-2.557	2.170e-02	0.290	-3.378	KAT5	K(lysine) acetyltransferase 5	11	65236064	AA886971	10524	11q13	Hs.397010	88	chromatin chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding nucleus nucleolus cytoplasm double-strand break repair chromatin assembly or disassembly DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator zinc ion binding acyltransferase activity chromatin modification histone acetylation transferase activity androgen receptor signaling pathway Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding perinuclear region of cytoplasm androgen receptor binding
210845_s_at	0.260	5.166	2.557	2.171e-02	0.290	-3.378	PLAUR	plasminogen activator, urokinase receptor	19	-48844571, -48842087	U08839	5329	19q13	Hs.466871	234	extracellular region plasma membrane plasma membrane cell motion chemotaxis signal transduction blood coagulation cell surface integral to membrane attachment of GPI anchor to protein extrinsic to membrane enzyme binding regulation of proteolysis U-plasminogen activator receptor activity anchored to membrane skeletal muscle regeneration	Complement and coagulation cascades
206612_at	-0.403	8.832	-2.557	2.171e-02	0.290	-3.379	CACNG1	calcium channel, voltage-dependent, gamma subunit 1	17	62471167	NM_000727	786	17q24	Hs.147989	8	voltage-gated ion channel activity calcium ion binding voltage-gated calcium channel complex ion transport calcium ion transport muscle contraction dihydropyridine-sensitive calcium channel activity membrane integral to membrane	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
243116_at	0.431	4.150	2.557	2.172e-02	0.290	-3.379	PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase-like 1	9	-129723630, -129723628	AI923090	138429	9q34.11	Hs.445486	2	nucleotide binding protein binding ATP binding cytoplasm membrane kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity transferase activity cell projection phosphatidylinositol metabolic process
1560220_a_at	0.257	3.579	2.557	2.173e-02	0.290	-3.379	CBY1	chibby homolog 1 (Drosophila)	22	37382603	BC008839	25776	22q12	Hs.334911 Hs.596584	20	nucleus Golgi apparatus trans-Golgi network beta-catenin binding protein localization nuclear speck negative regulation of Wnt receptor signaling pathway negative regulation of Wnt receptor signaling pathway identical protein binding fat cell differentiation negative regulation of transcription, DNA-dependent cardiac muscle cell differentiation
201267_s_at	-0.380	9.617	-2.556	2.174e-02	0.290	-3.380	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11	-47396895	AL545523	5702	11p12-p13	Hs.250758	57	nucleotide binding proteasome complex blastocyst development transcription coactivator activity transcription corepressor activity protein binding ATP binding nucleus cytoplasm cytosol hydrolase activity nucleoside-triphosphatase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
238337_s_at	-0.483	8.666	-2.556	2.176e-02	0.290	-3.380	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	5	34965454	BF678298	134218	5p13.2	Hs.131887	5	nucleic acid binding intracellular zinc ion binding heat shock protein binding metal ion binding
223503_at	0.377	3.412	2.556	2.176e-02	0.290	-3.381	TMEM163	transmembrane protein 163	2	-134929800	AF255647	81615	2q21.3	Hs.369471 Hs.595089	5	membrane integral to membrane
219022_at	-0.459	5.280	-2.556	2.177e-02	0.290	-3.381	C12orf43	chromosome 12 open reading frame 43	12	-119925230	NM_022895	64897	12q	Hs.528671	10
211698_at	-0.366	8.884	-2.556	2.177e-02	0.290	-3.381	EID1	EP300 interacting inhibitor of differentiation 1	15	46957581	AF349444	23741	15q21.1-q21.2	Hs.255973 Hs.714048	12	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding cellular_component nucleus cytoplasm cell cycle specific transcriptional repressor activity cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of transcription
206854_s_at	-0.517	6.392	-2.556	2.178e-02	0.290	-3.381	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	NM_003188	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
230800_at	0.392	6.495	2.555	2.179e-02	0.290	-3.382	ADCY4	adenylate cyclase 4	14	-23857409	AV699353	196883	14q12	Hs.443428	13	nucleotide binding magnesium ion binding adenylate cyclase activity ATP binding intracellular cAMP biosynthetic process G-protein signaling, coupled to cAMP nucleotide second messenger intracellular signaling cascade membrane integral to membrane dendrite	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Taste transduction GnRH signaling pathway Melanogenesis
201726_at	-0.433	8.899	-2.555	2.180e-02	0.290	-3.382	ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	19	-7929456	BC003376	1994	19p13.2	Hs.184492 Hs.713744	115	nucleotide binding mRNA binding nucleus multicellular organismal development identical protein binding mRNA stabilization
205337_at	0.301	2.805	2.555	2.180e-02	0.290	-3.382	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	AL139318	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
204435_at	-0.662	6.606	-2.555	2.181e-02	0.290	-3.382	NUPL1	nucleoporin like 1	13	24773665	NM_014778	9818	13q12.13	Hs.310453 Hs.719291	9	nucleus nuclear pore protein transport membrane mRNA transport intracellular protein transmembrane transport
202898_at	0.333	5.374	2.555	2.182e-02	0.290	-3.383	SDC3	syndecan 3	1	-31114899	NM_014654	9672	1pter-p22.3	Hs.158287	35	cytoskeletal protein binding membrane integral to membrane	ECM-receptor interaction Cell adhesion molecules (CAMs)
1553227_s_at	-0.395	5.098	-2.554	2.184e-02	0.291	-3.384	BRWD1	bromodomain and WD repeat domain containing 1	21	-39590234, -39484017, -39479273	NM_018963	54014	21q22.2	Hs.654740	8	protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter biological_process transcription regulator activity regulation of transcription
214873_at	0.289	3.851	2.554	2.185e-02	0.291	-3.384	LRP5L	low density lipoprotein receptor-related protein 5-like	22	-24077385, -24077385	AL137651	91355	22q11.23	Hs.634058	3	membrane
200086_s_at	0.363	11.778	2.554	2.185e-02	0.291	-3.384	COX4I1	cytochrome c oxidase subunit IV isoform 1	16	84390696	AA854966	1327	16q22-qter	Hs.433419	17	cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
210253_at	-0.382	4.230	-2.554	2.185e-02	0.291	-3.384	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	AF092095	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
203051_at	-0.221	6.643	-2.554	2.186e-02	0.291	-3.385	BAHD1	bromo adjacent homology domain containing 1	15	38520702	NM_014952	22893	15q15.1	Hs.22109	5	DNA binding
38671_at	0.322	7.151	2.553	2.191e-02	0.291	-3.387	PLXND1	plexin D1	3	-130756745	AB014520	23129	3q22.1	Hs.301685	10	receptor activity intracellular plasma membrane signal transduction multicellular organismal development integral to membrane
218250_s_at	-0.368	9.799	-2.552	2.191e-02	0.291	-3.387	CNOT7	CCR4-NOT transcription complex, subunit 7	8	-17133392, -17131110	NM_013354	29883	8p22-p21.3	Hs.645009 Hs.719129	19	nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter	RNA degradation
204170_s_at	-0.987	5.215	-2.552	2.191e-02	0.291	-3.387	CKS2	CDC28 protein kinase regulatory subunit 2	9	91115932	NM_001827	1164	9q22	Hs.83758	15	regulation of cyclin-dependent protein kinase activity cell cycle spindle organization meiosis I cell proliferation cyclin-dependent protein kinase regulator activity phosphoinositide-mediated signaling cell division
218517_at	-0.329	7.224	-2.552	2.192e-02	0.291	-3.387	PHF17	PHD finger protein 17	4	129950228, 129950228	NM_024900	79960	4q26-q27	Hs.12420	14	histone acetyltransferase complex protein binding nucleus cytoplasm apoptosis response to stress zinc ion binding negative regulation of cell growth histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation regulation of transcription metal ion binding
238327_at	0.476	3.656	2.552	2.194e-02	0.291	-3.388	ODF3B	outer dense fiber of sperm tails 3B	22	-49315703	AI962367	440836	22q13.33	Hs.531314	6
214084_x_at	0.310	5.565	2.552	2.195e-02	0.291	-3.388	NCF1C	neutrophil cytosolic factor 1C pseudogene	7	-74210380	AW072388	654817	7q11.23	Hs.647047 Hs.648940 Hs.655201	58	protein binding cytoplasm cell communication phosphoinositide binding
231480_at	0.266	4.688	2.551	2.197e-02	0.291	-3.389	SLC6A19	solute carrier family 6 (neutral amino acid transporter), member 19	5	1254709	AI636105	340024	5p15.33	Hs.481478	10	neurotransmitter:sodium symporter activity integral to plasma membrane neurotransmitter transport neutral amino acid transmembrane transporter activity symporter activity neutral amino acid transport membrane
233006_at	0.379	5.536	2.551	2.197e-02	0.291	-3.389	SEPT4	septin 4	17	-53952614, -53952614	AU147957	5414	17q22-q23	Hs.287518	29	nucleotide binding cytokinesis GTPase activity structural molecule activity protein binding GTP binding nucleus cytoplasm cell cycle
218648_at	-0.350	7.432	-2.551	2.200e-02	0.291	-3.390	CRTC3	CREB regulated transcription coactivator 3	15	88874201	NM_022769	64784	15q26.1	Hs.567572	10	nucleus cytoplasm interspecies interaction between organisms regulation of transcription
209331_s_at	-0.386	5.527	-2.551	2.200e-02	0.291	-3.390	MAX	MYC associated factor X	14	-64620214, -64614273, -64611597, -64542644	AA723514	4149	14q23	Hs.285354 Hs.712926	56	transcription factor activity transcription coactivator activity protein binding nucleus cytoplasm transcription from RNA polymerase II promoter regulation of transcription	MAPK signaling pathway Pathways in cancer Small cell lung cancer
201520_s_at	-0.526	9.375	-2.550	2.200e-02	0.291	-3.391	GRSF1	G-rich RNA sequence binding factor 1	4	-71900362, -71900362	BF034561	2926	4q13	Hs.309763	6	mRNA binding cytoplasm mRNA polyadenylation
1554661_s_at	-0.406	4.772	-2.550	2.202e-02	0.291	-3.391	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	BC036200	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
1552879_a_at	0.284	3.964	2.550	2.202e-02	0.291	-3.391	ATOH7	atonal homolog 7 (Drosophila)	10	-69660387	BC032621	220202	10q21.3 10q21.3-q22.1	Hs.175396	4	DNA binding nucleus multicellular organismal development nervous system development circadian rhythm entrainment of circadian clock cell differentiation transcription regulator activity regulation of transcription
225635_s_at	-0.439	4.809	-2.550	2.202e-02	0.291	-3.391	LOC401504	hypothetical gene supported by AK091718	9		BG535378	401504	9p13.2	Hs.446271	2
214180_at	0.328	5.544	2.550	2.202e-02	0.291	-3.391	MAN1C1	mannosidase, alpha, class 1C, member 1	1	25816545	AW340588	57134	1p35	Hs.197043	26	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding Golgi apparatus protein amino acid N-linked glycosylation metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds integral to Golgi membrane	N-Glycan biosynthesis Metabolic pathways
205073_at	-1.047	7.758	-2.550	2.202e-02	0.291	-3.391	CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	1	-60131567	NM_000775	1573	1p31.3-p31.2	Hs.152096	50	endoplasmic reticulum microsome fatty acid metabolic process icosanoid metabolic process regulation of heart contraction arachidonic acid epoxygenase activity electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	Arachidonic acid metabolism Linoleic acid metabolism Metabolic pathways
1570225_at	0.287	5.102	2.550	2.203e-02	0.291	-3.391	TMEM150B	transmembrane protein 150B	19	-60516038	BC020862	284417	19q13.42	Hs.382625	2	membrane integral to membrane
232938_at	0.250	4.389	2.550	2.204e-02	0.291	-3.392	SFMBT2	Scm-like with four mbt domains 2	10	-7244254	AL118884	57713	10p14	Hs.407983	3	nucleus regulation of transcription
1553732_s_at	0.261	5.387	2.549	2.206e-02	0.292	-3.393	CCDC123	coiled-coil domain containing 123	19	-38061743	NM_032816	84902	19q13.11	Hs.599703	3	protein binding mitochondrion
219922_s_at	-0.495	6.370	-2.549	2.207e-02	0.292	-3.393	LTBP3	latent transforming growth factor beta binding protein 3	11	-65062605	NM_021070	4054	11q13.1	Hs.289019	19	binding calcium ion binding extracellular region growth factor binding
237730_at	0.251	5.252	2.549	2.208e-02	0.292	-3.393	LOC100130700	similar to hCG2038355	16		AA824251	100130700	16p11.1	Hs.97712
227572_at	-0.377	6.840	-2.548	2.210e-02	0.292	-3.394	USP30	ubiquitin specific peptidase 30	12	107974762	AA528138	84749	12q24.11	Hs.486434 Hs.660996	7	ubiquitin thiolesterase activity mitochondrion mitochondrial outer membrane ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity membrane integral to membrane
211006_s_at	-1.993	6.748	-2.548	2.211e-02	0.292	-3.395	KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	20	-47421911	L02840	3745	20q13.2	Hs.84244	28	voltage-gated ion channel activity voltage-gated potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex membrane integral to membrane potassium ion binding	Taste transduction
238665_at	0.323	5.866	2.548	2.212e-02	0.292	-3.395	LOC100133142	similar to zinc finger protein 208	19		AI084583	100133142	19q13.42
237256_at	0.280	4.427	2.548	2.213e-02	0.292	-3.395	FBXL12	F-box and leucine-rich repeat protein 12	19	-9781942	AI479104	54850	19p13.2	Hs.12439	7	ubiquitin ligase complex cytoplasm ubiquitin-dependent protein catabolic process
223230_at	-0.381	5.815	-2.547	2.215e-02	0.292	-3.396	PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	1	52642806	AL521713	84950	1p33-p32.1	Hs.5301	5	nucleus spliceosomal complex mRNA processing RNA splicing
242499_at	0.290	5.024	2.547	2.216e-02	0.292	-3.397	U2AF1	U2 small nuclear RNA auxiliary factor 1	21	-43386134	AA448694	7307	21q22.3	Hs.365116	47	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex zinc ion binding RNA splicing Cajal body metal ion binding RS domain binding
215795_at	1.118	8.240	2.547	2.216e-02	0.292	-3.397	MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	20	33026866	AK000947	57644	20q11.22	Hs.414122	8	nucleotide binding motor activity actin binding ATP binding striated muscle thick filament striated muscle contraction membrane myosin complex	Tight junction
211724_x_at	-0.498	7.774	-2.547	2.217e-02	0.292	-3.397	MIOS	missing oocyte, meiosis regulator, homolog (Drosophila)	7	7573140	BC005883	54468	7p22-p21	Hs.520215	4
1556573_s_at	-0.249	4.715	-2.546	2.218e-02	0.292	-3.398	LOC286178	hypothetical protein LOC286178	8		AK090741	286178	8q12.1	Hs.255156	1
201020_at	-0.569	7.768	-2.546	2.218e-02	0.292	-3.398	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	22	30670478	NM_003405	7533	22q12.3	Hs.226755	76	actin binding insulin-like growth factor receptor binding cytoplasm glucocorticoid catabolic process intracellular protein transport transcription activator activity enzyme binding protein domain specific binding glucocorticoid receptor binding glucocorticoid receptor signaling pathway regulation of neuron differentiation positive regulation of transcription regulation of synaptic plasticity negative regulation of dendrite morphogenesis	Cell cycle Neurotrophin signaling pathway
208631_s_at	0.489	9.363	2.546	2.218e-02	0.292	-3.398	HADHA	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	2	-26267007	U04627	3030	2p23	Hs.516032	36	acyl-CoA binding 3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity fatty acid beta-oxidation multienzyme complex long-chain-enoyl-CoA hydratase activity long-chain-3-hydroxyacyl-CoA dehydrogenase activity lyase activity response to drug mitochondrial nucleoid NAD or NADH binding oxidation reduction	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Biosynthesis of unsaturated fatty acids Metabolic pathways
208922_s_at	-0.350	7.205	-2.546	2.219e-02	0.292	-3.398	NXF1	nuclear RNA export factor 1	11	-62316173	BC004904	10482	11q12-q13	Hs.523739 Hs.601546	45	nucleotide binding mRNA binding nucleocytoplasmic transporter activity protein binding intracellular nucleus nuclear pore nucleoplasm cytoplasm RNA export from nucleus transport nuclear speck poly(A)+ mRNA export from nucleus nuclear inclusion body interspecies interaction between organisms mRNA transport
41037_at	-0.470	7.512	-2.546	2.219e-02	0.292	-3.398	TEAD4	TEA domain family member 4	12	2938756, 2939222	U63824	7004	12p13.3-p13.2	Hs.94865	16	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter muscle organ development
200005_at	-0.435	8.377	-2.546	2.220e-02	0.292	-3.398	EIF3D	eukaryotic translation initiation factor 3, subunit D	22	-35236842	NM_003753	8664	22q13.1	Hs.55682	20	translation initiation factor activity translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation translational initiation
200922_at	-0.267	5.461	-2.546	2.220e-02	0.292	-3.398	KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	19	-53577638	NM_006801	10945	19q13.3	Hs.515515	14	receptor activity KDEL sequence binding protein binding membrane fraction endoplasmic reticulum ER-Golgi intermediate compartment protein retention in ER lumen intracellular protein transport membrane integral to membrane vesicle-mediated transport	Vibrio cholerae infection
204576_s_at	-0.427	6.347	-2.546	2.220e-02	0.292	-3.398	CLUAP1	clusterin associated protein 1	16	3490963, 3499894	AA207013	23059	16p13.3	Hs.155995	7	protein binding nucleus
219144_at	-0.680	9.919	-2.546	2.222e-02	0.292	-3.399	DUSP26	dual specificity phosphatase 26 (putative)	8	-33568392	NM_024025	78986	8p12	Hs.8719	6	protein tyrosine phosphatase activity nucleus cytoplasm Golgi apparatus protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
227719_at	1.476	7.120	2.546	2.222e-02	0.292	-3.399	SMAD9	SMAD family member 9	13	-36320206	AA934610	4093	13q12-q14	Hs.123119	20	transcription factor activity protein binding intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	TGF-beta signaling pathway
201327_s_at	-0.592	8.069	-2.545	2.223e-02	0.292	-3.399	CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	7	56086871	NM_001762	908	7p11.2	Hs.82916	17	nucleotide binding ATP binding cytoplasm chaperonin-containing T-complex protein folding unfolded protein binding
236998_at	0.279	5.013	2.545	2.224e-02	0.292	-3.400	CCDC56	coiled-coil domain containing 56	17	-38203177	AI056409	28958	17q21	Hs.16059	4	mitochondrion membrane integral to membrane
223301_s_at	0.362	6.164	2.545	2.225e-02	0.292	-3.400	CCDC82	coiled-coil domain containing 82	11	-95725576	AF245436	79780	11q21	Hs.525088	9	protein binding
244740_at	1.003	6.242	2.545	2.225e-02	0.292	-3.401	MGC9913	hypothetical protein MGC9913	19		BE855713	386759	19q13.43	Hs.23133	1
201455_s_at	-0.487	8.739	-2.544	2.227e-02	0.293	-3.401	NPEPPS	aminopeptidase puromycin sensitive	17	42963442	AJ132583	9520	17q21	Hs.443837	14	aminopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
236939_at	0.373	3.724	2.544	2.229e-02	0.293	-3.402	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	9	-20996364	AA687316	401494	9p21.3	Hs.716678	1	membrane integral to membrane
224484_s_at	-0.517	4.733	-2.544	2.229e-02	0.293	-3.402	BRMS1L	breast cancer metastasis-suppressor 1-like	14	35365347	BC006250	84312	14q13.2	Hs.525299	3	nucleus regulation of growth regulation of transcription
206372_at	-0.799	9.978	-2.544	2.231e-02	0.293	-3.403	MYF6	myogenic factor 6 (herculin)	12	79625576	NM_002469	4618	12q21	Hs.35937	12	somitogenesis transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter multicellular organismal development muscle organ development skeletal muscle tissue development negative regulation of transcription cell differentiation positive regulation of transcription
1565758_at	0.425	4.107	2.543	2.231e-02	0.293	-3.403	RPL13	ribosomal protein L13	16	88154590, 88154631	AW302784	6137	16q24.3 17p11.2	Hs.410817	17	RNA binding structural constituent of ribosome protein binding intracellular cytosol translational elongation cytosolic ribosome	Ribosome
203879_at	0.327	5.436	2.543	2.232e-02	0.293	-3.403	PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	1	9634376	U86453	5293	1p36.2	Hs.518451	40	nucleotide binding inositol or phosphatidylinositol kinase activity protein binding ATP binding phosphoinositide 3-kinase complex protein amino acid phosphorylation signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
228566_at	-0.342	5.756	-2.543	2.233e-02	0.293	-3.404	RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	18	-31823789	AA778694	55197	18q12.2	Hs.464912	3
213765_at	-0.954	7.777	-2.543	2.234e-02	0.293	-3.404	MFAP5	microfibrillar associated protein 5	12	-8689806	AW665892	8076	12p13.1-p12.3	Hs.512842	9	microfibril extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix
1557136_at	0.307	4.183	2.543	2.234e-02	0.293	-3.404	ATP13A4	ATPase type 13A4	3	-194602559	BG059633	84239	3q29	Hs.674423	4	nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity
211121_s_at	0.268	5.071	2.543	2.235e-02	0.293	-3.404	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	2	74635367	AF180527	1796	2p13	Hs.103854	52	insulin receptor binding protein binding cell surface receptor linked signal transduction transmembrane receptor protein tyrosine kinase signaling pathway
226436_at	-0.791	6.226	-2.543	2.235e-02	0.293	-3.404	RASSF4	Ras association (RalGDS/AF-6) domain family member 4	10	44775224	N49935	83937	10q11.21	Hs.522895	9	protein binding cell cycle signal transduction
1569335_a_at	0.367	5.044	2.542	2.237e-02	0.293	-3.405	STRA6	stimulated by retinoic acid gene 6 homolog (mouse)	15	-72273783, -72258862, -72258862, -72258862	BC015881	64220	15q24.1	Hs.24553	13	receptor activity plasma membrane transport integral to membrane protein complex
209919_x_at	0.306	5.464	2.542	2.237e-02	0.293	-3.405	GGT1	gamma-glutamyltransferase 1	22	23309717, 23329179, 23333654	L20490	2678	22q11.23	Hs.595809 Hs.645535	71	molecular_function gamma-glutamyltransferase activity protein binding cellular amino acid metabolic process glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity	Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways
1555844_s_at	-0.427	8.515	-2.542	2.237e-02	0.293	-3.405	HNRNPM	heterogeneous nuclear ribonucleoprotein M	19	8415802	AL713781	4670	19p13.3-p13.2	Hs.465808 Hs.666214	28	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding nucleus spliceosomal complex nucleolus integral to plasma membrane RNA splicing protein domain specific binding
227186_s_at	0.569	11.233	2.542	2.239e-02	0.293	-3.406	MRPL41	mitochondrial ribosomal protein L41	9	139566129	AI090841	64975	9q34.3	Hs.44017	10	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation apoptosis cell cycle
203584_at	0.257	9.146	2.541	2.240e-02	0.293	-3.406	TTC35	tetratricopeptide repeat domain 35	8	109525028	NM_014673	9694	8q23.1	Hs.654351	9	binding nucleus endoplasmic reticulum
225315_at	0.404	8.929	2.541	2.241e-02	0.293	-3.407	MRPL21	mitochondrial ribosomal protein L21	11	-68415321	BF344406	219927	11q13.3	Hs.503047	6	RNA binding structural constituent of ribosome intracellular mitochondrion ribosome translation
1553113_s_at	-0.683	5.357	-2.541	2.242e-02	0.293	-3.407	CDK8	cyclin-dependent kinase 8	13	25726755	BF700678	1024	13q12	Hs.382306	38	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation RNA polymerase II carboxy-terminal domain kinase activity transferase activity regulation of transcription
200065_s_at	-0.392	9.894	-2.540	2.244e-02	0.293	-3.408	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AF052179	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
1555620_a_at	0.238	6.581	2.540	2.246e-02	0.294	-3.409	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	19	-51815564	BC017857	5739	19q13.3	Hs.458324	55	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger cell-cell signaling	Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
1555760_a_at	-0.357	6.166	-2.539	2.250e-02	0.294	-3.410	RBM15	RNA binding motif protein 15	1	110683467	AF364037	64783	1p13	Hs.435947 Hs.708172	13	nucleotide binding RNA binding protein binding nucleus negative regulation of transcription interspecies interaction between organisms
1569629_x_at	0.212	4.124	2.539	2.250e-02	0.294	-3.410	LOC389906	similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1)	X		BC017231	389906	Xp22.33	Hs.636199 Hs.684492	1
244680_at	0.373	3.784	2.539	2.250e-02	0.294	-3.410	GLRB	glycine receptor, beta	4	158216726	AI701428	2743	4q31.3	Hs.32973	14	startle response ion channel activity extracellular ligand-gated ion channel activity protein binding membrane fraction plasma membrane integral to plasma membrane ion transport chloride transport neuropeptide signaling pathway synaptic transmission acrosome reaction nervous system development visual perception adult walking behavior glycine binding extracellular-glycine-gated chloride channel activity cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex regulation of membrane potential synapse postsynaptic membrane synaptic transmission, glycinergic righting reflex	Neuroactive ligand-receptor interaction
213198_at	-0.278	8.138	-2.539	2.250e-02	0.294	-3.411	ACVR1B	activin A receptor, type IB	12	50631752, 50631752, 50631752	AL117643	91	12q13	Hs.438918	39	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding in utero embryonic development hair follicle development protein serine/threonine kinase activity receptor activity ATP binding integral to plasma membrane induction of apoptosis signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway embryonic development cell surface membrane activin receptor activity, type I transferase activity peptidyl-threonine phosphorylation growth factor binding manganese ion binding negative regulation of cell growth ubiquitin protein ligase binding positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of erythrocyte differentiation SMAD binding protein amino acid autophosphorylation activin binding	MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia
203526_s_at	-0.683	4.157	-2.539	2.251e-02	0.294	-3.411	APC	adenomatous polyposis coli	5	112071116, 112101454	M74088	324	5q21-q22	Hs.158932	386	cytokinesis after mitosis kinetochore kidney development hair follicle development nucleus cytoplasm centrosome cytosol cytoplasmic microtubule protein complex assembly response to DNA damage stimulus negative regulation of microtubule depolymerization cell cycle arrest mitotic metaphase/anaphase transition mitotic cell cycle spindle assembly checkpoint axonogenesis beta-catenin binding microtubule binding axis specification anterior/posterior pattern formation dorsal/ventral pattern formation proximal/distal pattern formation lateral plasma membrane protein kinase regulator activity protein kinase binding negative regulation of Wnt receptor signaling pathway positive regulation of cell migration growth cone positive regulation of epithelial cell differentiation beta-catenin destruction complex positive regulation of microtubule polymerization cell projection membrane positive regulation of pseudopodium assembly T cell differentiation in the thymus axon part Axin-APC-beta-catenin-GSK3B complex somatic stem cell maintenance negative regulation of odontogenesis cell projection positive regulation of apoptosis negative regulation of apoptosis negative regulation of MAPKKK cascade skin development regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process negative regulation of cyclin-dependent protein kinase activity positive regulation of cell adhesion muscle maintenance thymus development negative regulation of epithelial cell proliferation regulation of nitrogen compound metabolic process chromosome organization regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye Wnt receptor signaling pathway through beta-catenin Wnt receptor signaling pathway through beta-catenin	Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma
229799_s_at	-0.761	4.985	-2.539	2.251e-02	0.294	-3.411	NCAM1	neural cell adhesion molecule 1	11	112337204, 112337204	AI569787	4684	11q23.1	Hs.503878	120	protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane	Cell adhesion molecules (CAMs) Prion diseases
236937_at	-0.488	5.404	-2.539	2.251e-02	0.294	-3.411	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)	3	186012624	BF108423	23355	3q27.2	Hs.269263	6	protein binding zinc ion binding metal ion binding
229969_at	-0.382	5.585	-2.539	2.252e-02	0.294	-3.411	SEC63	SEC63 homolog (S. cerevisiae)	6	-108295652	AV723931	11231	6q21	Hs.26904	14	receptor activity endoplasmic reticulum protein folding protein targeting to membrane protein transport membrane integral to membrane heat shock protein binding unfolded protein binding
212009_s_at	-0.932	6.851	-2.539	2.253e-02	0.294	-3.411	STIP1	stress-induced-phosphoprotein 1	11	63710162	AL553320	10963	11q13	Hs.337295	34	protein binding nucleus cytoplasm Golgi apparatus response to stress	Prion diseases
241754_at	0.330	3.117	2.538	2.254e-02	0.294	-3.412	SCAI	suppressor of cancer cell invasion	9	-126744710	AA829836	286205	9q33.3	Hs.59504	4	transcription corepressor activity protein binding protein binding nucleus cytoplasm negative regulation of signal transduction membrane integral to membrane negative regulation of cell migration negative regulation of Rho protein signal transduction regulation of transcription
219500_at	0.308	5.973	2.538	2.254e-02	0.294	-3.412	CLCF1	cardiotrophin-like cytokine factor 1	11	-66888214	NM_013246	23529	11q13.3	Hs.502977	13	cytokine activity extracellular region extracellular space JAK-STAT cascade growth factor activity cytokine-mediated signaling pathway B cell differentiation positive regulation of tyrosine phosphorylation of Stat3 protein negative regulation of apoptosis	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
203921_at	0.294	4.537	2.538	2.257e-02	0.294	-3.413	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	3	144321357	NM_004267	9435	3q24	Hs.8786	19	N-acetylglucosamine 6-O-sulfotransferase activity Golgi apparatus trans-Golgi network carbohydrate metabolic process N-acetylglucosamine metabolic process sulfur metabolic process inflammatory response multicellular organismal development membrane integral to membrane transferase activity intrinsic to Golgi membrane	Keratan sulfate biosynthesis Metabolic pathways
208616_s_at	-0.517	10.542	-2.537	2.259e-02	0.294	-3.414	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	U48297	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
213673_x_at	0.332	5.375	2.537	2.259e-02	0.294	-3.414	NENF	neuron derived neurotrophic factor	1	210672851	AA156251	29937	1q32.3	Hs.461787	7	extracellular region extracellular space growth factor activity heme binding positive regulation of MAPKKK cascade metal ion binding
219193_at	-0.270	6.677	-2.537	2.259e-02	0.294	-3.414	WDR70	WD repeat domain 70	5	37415168	NM_018034	55100	5p13.2	Hs.213690	2
200087_s_at	-0.564	9.470	-2.536	2.262e-02	0.294	-3.415	TMED2	transmembrane emp24 domain trafficking protein 2	12	122635028	AK024976	10959	12q24.31	Hs.592682 Hs.75914	10	protein binding microsome ER-Golgi intermediate compartment Golgi apparatus protein transport membrane integral to membrane vesicle-mediated transport cytoplasmic vesicle zymogen granule membrane
201464_x_at	-0.486	9.248	-2.536	2.264e-02	0.294	-3.416	JUN	jun oncogene	1	-59019050	BG491844	3725	1p32-p31	Hs.714791	443	nuclear chromosome transcription factor activity RNA polymerase II transcription factor activity Rho GTPase activator activity nucleus transcription factor complex cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation transcription factor binding negative regulation of cell proliferation cellular process promoter binding negative regulation of protein amino acid autophosphorylation leading edge cell differentiation response to drug positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein dimerization activity regulation of cell cycle SMAD protein signal transduction R-SMAD binding	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma
213615_at	-0.288	5.452	-2.536	2.265e-02	0.294	-3.416	LPCAT3	lysophosphatidylcholine acyltransferase 3	12	-6955607	AA773554	10162	12p13	Hs.655248	15	endoplasmic reticulum acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity 1-acylglycerophosphocholine O-acyltransferase activity
218172_s_at	-0.650	5.866	-2.536	2.266e-02	0.294	-3.417	DERL1	Der1-like domain family, member 1	8	-124094748	NM_018630	79139	8q24.13	Hs.241576	28	receptor activity protein binding endoplasmic reticulum endoplasmic reticulum response to unfolded protein protein transport membrane integral to membrane intracellular transport of viral proteins in host cell integral to endoplasmic reticulum membrane ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol MHC class I protein binding interspecies interaction between organisms	Amyotrophic lateral sclerosis (ALS)
209103_s_at	-0.355	8.232	-2.535	2.268e-02	0.294	-3.417	UFD1L	ubiquitin fusion degradation 1 like (yeast)	22	-17817463	BC001049	7353	22q11.21	Hs.474213	22	skeletal system development ubiquitin-specific protease activity protein binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process
230802_at	-0.636	3.816	-2.535	2.269e-02	0.295	-3.418	ARHGAP24	Rho GTPase activating protein 24	4	86615307, 86918874, 87070449	AI761947	83478	4q21.23-q21.3	Hs.444229	14	angiogenesis GTPase activator activity protein binding intracellular cytoplasm cytoskeleton adherens junction focal adhesion signal transduction multicellular organismal development cell junction cell differentiation cell projection
224775_at	-0.284	6.417	-2.534	2.271e-02	0.295	-3.419	IWS1	IWS1 homolog (S. cerevisiae)	2	-127954852	AW451291	55677	2q14.3	Hs.469879	12	nucleus
219412_at	0.496	3.756	2.534	2.275e-02	0.295	-3.420	RAB38	RAB38, member RAS oncogene family	11	-87486078	NM_022337	23682	11q14	Hs.591975	10	nucleotide binding GTPase activity protein binding GTP binding cellular_component soluble fraction insoluble fraction cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane organelle organization small GTPase mediated signal transduction protein transport melanosome vesicular fraction
222127_s_at	-0.445	7.527	-2.534	2.275e-02	0.295	-3.420	EXOC1	exocyst complex component 1	4	56414572	AK023461	55763	4q12	Hs.269665	13	exocyst exocytosis protein transport
221191_at	0.261	4.968	2.534	2.275e-02	0.295	-3.420	STAG3L1	stromal antigen 3-like 1	7	74826382	NM_018991	54441	7q11.23-q21.1	Hs.632310 Hs.661254 Hs.709564	2
202900_s_at	-0.459	7.026	-2.533	2.279e-02	0.295	-3.422	NUP88	nucleoporin 88kDa	17	-5230143	NM_002532	4927	17p13.2	Hs.584784	24	transporter activity nucleus nuclear pore cytosol protein transport mRNA transport intracellular protein transmembrane transport
224884_at	-0.600	6.762	-2.533	2.280e-02	0.295	-3.422	AKAP13	A kinase (PRKA) anchor protein 13	15	83724874, 84021271	AW575773	11214	15q24-q25	Hs.459211 Hs.710656	38	cAMP-dependent protein kinase activity signal transducer activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular membrane fraction nucleus cytoplasm intracellular signaling cascade biological_process zinc ion binding membrane diacylglycerol binding regulation of Rho protein signal transduction metal ion binding
218577_at	-0.415	7.135	-2.533	2.280e-02	0.295	-3.422	LRRC40	leucine rich repeat containing 40	1	-70383084	NM_017768	55631	1p31.1	Hs.147836	6	protein binding
212158_at	-0.733	6.984	-2.532	2.281e-02	0.295	-3.423	SDC2	syndecan 2	8	97575057	AL577322	6383	8q22-q23	Hs.1501 Hs.598247	72	molecular_function integral to plasma membrane cytoskeletal protein binding biological_process membrane	ECM-receptor interaction Cell adhesion molecules (CAMs)
212065_s_at	-0.692	4.912	-2.532	2.283e-02	0.295	-3.424	USP34	ubiquitin specific peptidase 34	2	-61268093	AW502434	9736	2p15	Hs.644708	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
221199_at	0.387	5.818	2.532	2.284e-02	0.295	-3.424	GFRA4	GDNF family receptor alpha 4	20	-3587938	NM_022139	64096	20p13-p12	Hs.302025	7	receptor activity extracellular region plasma membrane anchored to membrane
235707_at	-0.462	4.079	-2.532	2.284e-02	0.295	-3.424	LOC221710	hypothetical protein LOC221710	6	11202251	AW994270	221710	6p24.2	Hs.656600	1
215766_at	0.355	5.191	2.531	2.285e-02	0.295	-3.424	GSTA1	glutathione S-transferase alpha 1	6	-52764137	AL096729	2938	6p12.1	Hs.446309	104	glutathione transferase activity cytoplasm glutathione metabolic process metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
202010_s_at	-0.302	6.534	-2.531	2.286e-02	0.295	-3.424	ZNF410	zinc finger protein 410	14	73423338	NM_021188	57862	14q24.3	Hs.270869	9	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
210275_s_at	-0.632	10.431	-2.531	2.286e-02	0.295	-3.425	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AF062347	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
207148_x_at	-1.120	11.243	-2.531	2.287e-02	0.295	-3.425	MYOZ2	myozenin 2	4	120276386	NM_016599	51778	4q26-q27	Hs.381047	16	protein binding cytoplasm biological_process actin cytoskeleton sarcomere Z disc protein phosphatase 2B binding
1553314_a_at	0.243	3.026	2.531	2.287e-02	0.295	-3.425	KIF19	kinesin family member 19	17	69833945	NM_153209	124602	17q25.1	Hs.372773	6	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement
217760_at	-0.302	7.070	-2.531	2.287e-02	0.295	-3.425	TRIM44	tripartite motif-containing 44	11	35640928	AA176780	54765	11p13	Hs.192103	10	intracellular zinc ion binding metal ion binding
203138_at	-0.484	8.667	-2.531	2.287e-02	0.295	-3.425	HAT1	histone acetyltransferase 1	2	172487180	NM_003642	8520	2q31.2-q33.1	Hs.632532	14	histone acetyltransferase activity protein binding nucleus cytoplasm DNA packaging chromatin silencing at telomere internal protein amino acid acetylation acyltransferase activity chromatin modification histone acetylation transferase activity
202979_s_at	-0.678	5.176	-2.531	2.288e-02	0.295	-3.425	CREBZF	CREB/ATF bZIP transcription factor	11	-85046257	NM_021212	58487	11q14	Hs.535319 Hs.595940 Hs.714910	12	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent response to virus negative regulation of transcription specific transcriptional repressor activity sequence-specific DNA binding negative regulation of gene expression, epigenetic regulation of transcription factor activity
240337_at	0.279	3.597	2.531	2.289e-02	0.295	-3.426	RHOA	ras homolog gene family, member A	3	-49371582	AW173151	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
227768_at	-0.376	6.822	-2.530	2.289e-02	0.295	-3.426	ZNF407	zinc finger protein 407	18	70471906, 70471906, 70471906	AB051490	55628	18q23	Hs.536490	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
208097_s_at	-0.715	5.000	-2.530	2.291e-02	0.295	-3.426	TMX1	thioredoxin-related transmembrane protein 1	14	50776635	NM_030755	81542	14q22.1	Hs.125221	10	membrane fraction nucleus endoplasmic reticulum endoplasmic reticulum membrane DNA replication transport ER to Golgi vesicle-mediated transport anti-apoptosis response to stress signal transduction cell proliferation disulfide oxidoreductase activity membrane integral to membrane electron transport chain arsenate reductase (thioredoxin) activity leukocyte activation cell redox homeostasis positive regulation of transcription, DNA-dependent positive regulation of growth
242469_at	0.257	5.067	2.530	2.291e-02	0.295	-3.426	LOC120376	Uncharacterized protein LOC120376	11	110675185	AI590055	120376	11q23.1	Hs.31409	6
205643_s_at	0.378	3.264	2.530	2.292e-02	0.295	-3.427	PPP2R2B	protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform	5	-145949260, -145949260, -145949260, -145949260, -145949260	NM_004576	5521	5q31-q32	Hs.655213	48	protein phosphatase type 2A complex signal transduction cell death protein phosphatase type 2A regulator activity	Tight junction
227539_at	-0.796	5.704	-2.530	2.293e-02	0.295	-3.427	GNA13	guanine nucleotide binding protein (G protein), alpha 13	17	-60435870	AW298099	10672	17q24.3	Hs.515018	57	nucleotide binding patterning of blood vessels in utero embryonic development GTPase activity signal transducer activity protein binding GTP binding cell motion signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade Rho protein signal transduction regulation of cell shape membrane guanyl nucleotide binding cell differentiation platelet activation regulation of cell migration melanosome	Vascular smooth muscle contraction Long-term depression Regulation of actin cytoskeleton
233736_at	0.322	4.279	2.530	2.293e-02	0.295	-3.427	OR51J1	olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene)	11		AF137396	79470	11p15.4		1	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus
218618_s_at	-0.547	5.976	-2.530	2.294e-02	0.295	-3.427	FNDC3B	fibronectin type III domain containing 3B	3	173240111, 173241037	NM_022763	64778	3q26.31	Hs.159430	9	endoplasmic reticulum membrane integral to membrane
229805_at	0.286	5.187	2.529	2.294e-02	0.295	-3.428	ZDHHC22	zinc finger, DHHC-type containing 22	14	-76667365	AI363193	283576	14q24.3	Hs.525485	5	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
204361_s_at	0.860	4.788	2.529	2.295e-02	0.295	-3.428	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	AB014486	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
209362_at	-0.504	7.983	-2.529	2.296e-02	0.295	-3.428	MED21	mediator complex subunit 21	12	27066749	AI688580	9412	12p11.23	Hs.286145	27	blastocyst development RNA polymerase II transcription factor activity transcription coactivator activity DNA-directed RNA polymerase activity protein binding nucleus DNA-directed RNA polymerase II, core complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter
213996_at	-0.822	5.660	-2.529	2.298e-02	0.296	-3.429	YPEL1	yippee-like 1 (Drosophila)	22	-20381825	NM_013313	29799	22q11.2	Hs.517436	7	nucleus
224635_s_at	-0.464	7.802	-2.528	2.299e-02	0.296	-3.430	BIRC6	baculoviral IAP repeat-containing 6	2	32435599	AI017106	57448	2p22-p21	Hs.150107	14	ubiquitin-protein ligase activity cysteine-type endopeptidase inhibitor activity protein binding cellular_component intracellular membrane fraction apoptosis anti-apoptosis positive regulation of cell proliferation ligase activity modification-dependent protein catabolic process peptidase inhibitor activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
209067_s_at	-0.381	9.175	-2.528	2.300e-02	0.296	-3.430	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	D89092	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
219203_at	0.256	8.086	2.528	2.301e-02	0.296	-3.430	FAM158A	family with sequence similarity 158, member A	14	-23678013	NM_016049	51016	14q11.2	Hs.271614	4
208030_s_at	-0.328	9.705	-2.528	2.302e-02	0.296	-3.431	ADD1	adducin 1 (alpha)	4	2815381	NM_001119	118	4p16.3	Hs.183706 Hs.701490	139	calmodulin binding nucleus cytoplasm cytosol cytoskeleton plasma membrane transcription factor binding F-actin capping protein complex actin cytoskeleton organization spectrin binding positive regulation of protein binding protein homodimerization activity metal ion binding protein heterodimerization activity actin filament binding barbed-end actin filament capping actin filament bundle formation
211581_x_at	0.411	5.299	2.528	2.302e-02	0.296	-3.431	LST1	leukocyte specific transcript 1	6	31661949, 31662603, 3000093, 3000747, 2801557, 2802211	AF000426	7940	6p21.3	Hs.436066	20	cell morphogenesis molecular_function protein binding cytoplasm Golgi apparatus immune response regulation of cell shape anatomical structure morphogenesis membrane integral to membrane dendrite development negative regulation of lymphocyte proliferation
211036_x_at	-0.362	9.183	-2.528	2.302e-02	0.296	-3.431	ANAPC5	anaphase promoting complex subunit 5	12	-120230432, -120230432	BC006301	51433	12q24.31	Hs.7101	28	G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
206329_at	0.573	6.287	2.527	2.304e-02	0.296	-3.431	EXTL1	exostoses (multiple)-like 1	1	26220857	NM_004455	2134	1p36.1	Hs.150956	11	skeletal system development protein binding endoplasmic reticulum membrane integral to membrane transferase activity, transferring hexosyl groups intrinsic to endoplasmic reticulum membrane glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Heparan sulfate biosynthesis Metabolic pathways
203802_x_at	-0.273	7.104	-2.527	2.305e-02	0.296	-3.432	NSUN5	NOL1/NOP2/Sun domain family, member 5	7	-72355161	NM_018044	55695	7q11.23	Hs.647060	9	methyltransferase activity transferase activity
243179_at	0.677	4.889	2.527	2.305e-02	0.296	-3.432	LOC100130360	hypothetical LOC100130360	6		BG231554	100130360	6p22.3
204685_s_at	-1.288	7.048	-2.527	2.306e-02	0.296	-3.432	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	3	-10340706	R52647	491	3p25.3	Hs.268942	30	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding cytoplasm plasma membrane ATP biosynthetic process cation transport calcium ion transport sensory perception of sound metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances neuron differentiation	Calcium signaling pathway
227326_at	-0.502	6.757	-2.526	2.309e-02	0.296	-3.434	MXRA7	matrix-remodelling associated 7	17	-72187245, -72183403	BE966768	439921	17q25.1	Hs.250723 Hs.597019 Hs.707692	4	membrane integral to membrane
218187_s_at	-0.253	6.176	-2.526	2.310e-02	0.296	-3.434	C8orf33	chromosome 8 open reading frame 33	8	146248627	NM_023080	65265	8q24.3	Hs.169615	3
226718_at	-0.408	6.567	-2.525	2.313e-02	0.296	-3.435	AMIGO1	adhesion molecule with Ig-like domain 1	1	-109850968	AA001423	57463	1p13.3	Hs.709892	5	protein binding cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development nervous system development axonal fasciculation membrane integral to membrane cell differentiation axon myelination cell projection positive regulation of axonogenesis
203743_s_at	-0.461	7.018	-2.525	2.313e-02	0.296	-3.435	TDG	thymine-DNA glycosylase	12	102883722	NM_003211	6996	12q24.1	Hs.584809	47	damaged DNA binding protein binding nucleus nucleoplasm nucleoplasm base-excision repair mismatch repair response to DNA damage stimulus metabolic process pyrimidine-specific mismatch base pair DNA N-glycosylase activity DNA N-glycosylase activity mismatched DNA binding depyrimidination	Base excision repair
1558486_at	0.475	5.671	2.525	2.313e-02	0.296	-3.435	ZNF493	zinc finger protein 493	19	21371760, 21371760	BC022394	284443	19p12	Hs.656558	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203877_at	0.446	4.230	2.525	2.313e-02	0.296	-3.435	MMP11	matrix metallopeptidase 11 (stromelysin 3)	22	22445035	NM_005940	4320	22q11.2 22q11.23	Hs.143751	30	metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix proteolysis multicellular organismal development peptidase activity zinc ion binding collagen catabolic process
209233_at	-0.423	7.508	-2.525	2.316e-02	0.296	-3.436	EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)	12	6950204	U72514	10436	12p13	Hs.558447	13	nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing
203465_at	-0.673	8.070	-2.524	2.318e-02	0.297	-3.437	MRPL19	mitochondrial ribosomal protein L19	2	75727416	NM_014763	9801	2q11.1-q11.2	Hs.44024	11	structural constituent of ribosome intracellular nucleus mitochondrion ribosome translation nuclear membrane
207922_s_at	-0.295	7.479	-2.524	2.318e-02	0.297	-3.437	MAEA	macrophage erythroblast attacher	4	1273671	NM_005882	10296	4p16.3	Hs.139896	5	actin binding membrane fraction nucleus cytoplasm spindle contractile ring cytoskeleton plasma membrane integral to plasma membrane cell cycle cell adhesion regulation of mitotic cell cycle nuclear matrix negative regulation of myeloid cell apoptosis erythrocyte maturation cell division
208447_s_at	-0.506	6.415	-2.523	2.324e-02	0.297	-3.439	PRPS1	phosphoribosyl pyrophosphate synthetase 1	X	106758309	NM_002764	5631	Xq21.32-q24	Hs.56	26	nucleotide binding magnesium ion binding ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding cytosol purine base metabolic process purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process kinase activity transferase activity urate biosynthetic process protein homodimerization activity hypoxanthine biosynthetic process	Pentose phosphate pathway Purine metabolism Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
210044_s_at	0.378	6.381	2.522	2.326e-02	0.297	-3.440	LYL1	lymphoblastic leukemia derived sequence 1	19	-13070846	BC002796	4066	19p13.2	Hs.46446	15	DNA binding nucleus transcription regulator activity regulation of transcription
230603_at	0.331	5.193	2.522	2.328e-02	0.297	-3.441	COL27A1	collagen, type XXVII, alpha 1	9	115958051	W94813	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
230263_s_at	-0.975	3.961	-2.522	2.328e-02	0.297	-3.441	DOCK5	dedicator of cytokinesis 5	8	25098203	BF447954	80005	8p21.2	Hs.195403	7	guanyl-nucleotide exchange factor activity cytoplasm
213172_at	-0.555	3.701	-2.522	2.329e-02	0.297	-3.441	TTC9	tetratricopeptide repeat domain 9	14	70178256	AW235608	23508	14q24.2	Hs.79170	5	binding protein folding
1555970_at	0.324	4.814	2.522	2.330e-02	0.298	-3.442	FBXO28	F-box protein 28	1	222368413	AU154086	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
207654_x_at	-0.434	6.634	-2.521	2.331e-02	0.298	-3.442	DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	1	93584065	NM_001938	1810	1p22.1	Hs.348418	23	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity intracellular nucleus transcription factor binding sequence-specific DNA binding regulation of transcription
230973_at	0.263	4.992	2.521	2.331e-02	0.298	-3.442	SH2D5	SH2 domain containing 5	1	-20918811	AI937119	400745	1p36.12	Hs.591522	2	protein binding
224846_at	0.264	5.271	2.521	2.333e-02	0.298	-3.442	SHKBP1	SH3KBP1 binding protein 1	19	45774596	AI348000	92799	19q13.2	Hs.26506	7	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
1557123_a_at	0.264	4.982	2.521	2.333e-02	0.298	-3.443	CHADL	chondroadherin-like	22	-39955459	BC040188	150356	22q13.2	Hs.344488 Hs.714982	2	protein binding extracellular region proteinaceous extracellular matrix
1557170_at	0.265	5.687	2.521	2.334e-02	0.298	-3.443	NEK8	NIMA (never in mitosis gene a)- related kinase 8	17	24079958	AI073943	284086	17q11.1	Hs.448468	8	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
206734_at	-0.444	5.692	-2.521	2.334e-02	0.298	-3.443	JRKL	jerky homolog-like (mouse)	11	95762805	NM_003772	8690	11q21	Hs.105940	4	DNA binding nucleus central nervous system development regulation of transcription
224418_x_at	0.257	4.398	2.520	2.335e-02	0.298	-3.443	PMCHL1	pro-melanin-concentrating hormone-like 1	5	22178217	AY008407	5369	5p14.3	Hs.247975	6
219730_at	-0.538	4.784	-2.520	2.336e-02	0.298	-3.444	MED18	mediator complex subunit 18	1	28528099	NM_017638	54797	1p35.3	Hs.479911	6	nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity identical protein binding regulation of transcription
231987_at	0.345	6.030	2.520	2.337e-02	0.298	-3.444	LOC728264	hypothetical LOC728264	5	148766632	AW081196	728264	5q32	Hs.519666	1
225619_at	-0.499	3.022	-2.520	2.338e-02	0.298	-3.444	SLAIN1	SLAIN motif family, member 1	13	77170470, 77213295	AV730849	122060	13q22.3	Hs.349955	4
200945_s_at	-0.253	8.771	-2.520	2.339e-02	0.298	-3.445	SEC31A	SEC31 homolog A (S. cerevisiae)	4	-83958837	NM_014933	22872	4q21.22	Hs.370024	20	cytoplasm endoplasmic reticulum ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport protein transport membrane membrane organization vesicle-mediated transport COPII vesicle coat cytoplasmic vesicle calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion
208366_at	0.351	3.531	2.520	2.339e-02	0.298	-3.445	PCDH11X	protocadherin 11 X-linked	X	90920959, 90976314, 90976314	NM_014522	27328	Xq21.3	Hs.655673	16	calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion
227226_at	0.327	4.460	2.520	2.339e-02	0.298	-3.445	MRAP2	melanocortin 2 receptor accessory protein 2	6	84800138	AA418816	112609	6q14.2	Hs.370055	8
214160_at	0.214	3.926	2.519	2.340e-02	0.298	-3.445	CDK6	cyclin-dependent kinase 6	7	-92072172, -92072172	AI738463	1021	7q21-q22	Hs.119882	95	G1 phase of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex ruffle positive regulation of cell-matrix adhesion cyclin-dependent protein kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation regulation of gene expression regulation of gene expression transferase activity hemopoiesis cyclin binding gliogenesis cell dedifferentiation regulation of erythrocyte differentiation negative regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of fibroblast proliferation negative regulation of epithelial cell proliferation cell division	Cell cycle p53 signaling pathway Pathways in cancer Pancreatic cancer Glioma Melanoma Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer
1561038_at	0.314	4.114	2.519	2.341e-02	0.298	-3.446	ZNF81	zinc finger protein 81	X	47581244	BC039609	347344	Xp11.23	Hs.114246	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225585_at	-0.763	7.662	-2.519	2.342e-02	0.298	-3.446	RAP2A	RAP2A, member of RAS oncogene family	13	96884475	AI963476	5911	13q34	Hs.508480	34	nucleotide binding GTPase activity protein binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction
226604_at	-0.373	5.815	-2.519	2.343e-02	0.298	-3.447	TMTC3	transmembrane and tetratricopeptide repeat containing 3	12	87060203	AA418403	160418	12q21.32	Hs.331268	7	binding membrane integral to membrane
229441_at	-0.478	5.489	-2.518	2.347e-02	0.298	-3.448	PRSS23	protease, serine, 23	11	86189138	AI569872	11098	11q14.1	Hs.25338	13	serine-type endopeptidase activity extracellular region nucleus proteolysis peptidase activity
215379_x_at	0.652	6.110	2.518	2.347e-02	0.298	-3.448	IGL@	immunoglobulin lambda locus	22		AV698647	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
220834_at	0.265	2.996	2.518	2.349e-02	0.298	-3.449	MS4A12	membrane-spanning 4-domains, subfamily A, member 12	11	60016826	NM_017716	54860	11q12	Hs.272789	7	receptor activity signal transduction membrane integral to membrane
219461_at	0.289	4.916	2.517	2.349e-02	0.298	-3.449	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	15	38296920, 38319326	AJ236915	56924	15q14	Hs.513645	13	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
201414_s_at	-0.332	7.696	-2.517	2.350e-02	0.298	-3.449	NAP1L4	nucleosome assembly protein 1-like 4	11	-2922235	NM_005969	4676	11p15.5	Hs.501684 Hs.695395	12	nucleus chromatin assembly complex cytoplasm nucleosome assembly unfolded protein binding
203265_s_at	-0.449	5.678	-2.517	2.351e-02	0.298	-3.449	MAP2K4	mitogen-activated protein kinase kinase 4	17	11864859	AA810268	6416	17p11.2	Hs.514681	92	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding protein amino acid phosphorylation signal transduction JNK cascade transferase activity	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection
238338_at	0.275	3.867	2.517	2.353e-02	0.298	-3.450	DCAF8	DDB1 and CUL4 associated factor 8	1	-158475636, -158475636, -158452128, -158452128	AL134577	50717	1q22-q23	Hs.632447	10	protein binding
200895_s_at	-0.448	8.114	-2.517	2.353e-02	0.298	-3.450	FKBP4	FK506 binding protein 4, 59kDa	12	2774368	NM_002014	2288	12p13.33	Hs.524183 Hs.713721	47	peptidyl-prolyl cis-trans isomerase activity ATP binding GTP binding FK506 binding intracellular nucleus nucleolus cytoplasm protein folding steroid hormone receptor complex assembly copper ion transport embryo implantation isomerase activity protein binding, bridging heat shock protein binding protein complex localization glucocorticoid receptor binding male sex differentiation phosphoprotein binding
226322_at	-0.535	8.258	-2.517	2.353e-02	0.298	-3.450	TMTC1	transmembrane and tetratricopeptide repeat containing 1	12	-29545023	BF109231	83857	12p11.22	Hs.401954	3	binding membrane integral to membrane
203721_s_at	-0.636	7.769	-2.516	2.354e-02	0.298	-3.451	UTP18	UTP18, small subunit (SSU) processome component, homolog (yeast)	17	46692895	NM_016001	51096	17q21.33	Hs.709327	11	nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing
206208_at	0.395	6.232	2.516	2.355e-02	0.298	-3.451	CA4	carbonic anhydrase IV	17	55582083	NM_000717	762	17q23	Hs.89485	30	carbonate dehydratase activity membrane fraction plasma membrane one-carbon metabolic process visual perception zinc ion binding lyase activity anchored to membrane metal ion binding response to stimulus	Nitrogen metabolism
242918_at	-0.873	4.860	-2.516	2.355e-02	0.298	-3.451	NASP	nuclear autoantigenic sperm protein (histone-binding)	1	45822303	AU144734	4678	1p34.1	Hs.319334	28	blastocyst development protein binding nucleus cytoplasm DNA replication cell cycle cell proliferation protein transport histone exchange Hsp90 protein binding
221534_at	-0.299	7.863	-2.516	2.357e-02	0.298	-3.452	C11orf68	chromosome 11 open reading frame 68	11	-65440859	AF073483	83638	11q13.1	Hs.433573	6
228230_at	0.242	5.044	2.515	2.360e-02	0.299	-3.453	PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285	20	-61659882, -61659882	AL121829	85441	20q13.33	Hs.517180	9	nucleotide binding DNA binding transcription coactivator activity RNA binding helicase activity ribonuclease activity ATP binding intracellular nucleus zinc ion binding hydrolase activity regulation of transcription metal ion binding
227161_at	-0.464	5.309	-2.515	2.360e-02	0.299	-3.453	NOM1	nucleolar protein with MIF4G domain 1	7	156435177	AI419857	64434	7q36.3	Hs.15825	6	protein binding nucleus nucleolus biological_process RNA metabolic process
202548_s_at	-0.269	8.324	-2.515	2.361e-02	0.299	-3.453	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	13	110565624, 110604061, 110637173	NM_003899	8874	13q34	Hs.508738	49	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytosol intracellular signaling cascade regulation of Rho protein signal transduction	Regulation of actin cytoskeleton
203567_s_at	-0.519	6.397	-2.515	2.361e-02	0.299	-3.453	TRIM38	tripartite motif-containing 38	6	26071049	AU157590	10475	6p21.3	Hs.584851	7	signal transducer activity protein binding cellular_component intracellular zinc ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
231816_s_at	0.304	4.612	2.515	2.362e-02	0.299	-3.453	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	1	-152787674	AI986085	55585	1q21.3	Hs.607928	7	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
235291_s_at	0.370	4.037	2.515	2.362e-02	0.299	-3.454	FLJ32255	hypothetical protein LOC643977	5		BE875232	643977	5p12	Hs.535791	1
211743_s_at	0.315	4.175	2.515	2.363e-02	0.299	-3.454	PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	11	-56911409	BC005929	5553	11q12	Hs.512633	51	binding sugar binding extracellular region immune response heparin binding defense response to bacterium	Asthma
1554485_s_at	0.451	3.900	2.514	2.364e-02	0.299	-3.454	TMEM37	transmembrane protein 37	2	119905915	BI825302	140738	2q14.2	Hs.26216	3	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane
239052_at	0.257	3.990	2.514	2.365e-02	0.299	-3.455	HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	4	-83493490	AW968636	3184	4q21.1-q21.2	Hs.480073	64	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding RNA binding protein binding nucleus chromosome regulation of transcription, DNA-dependent RNA processing RNA catabolic process biological_process transcription activator activity heterogeneous nuclear ribonucleoprotein complex telomeric DNA binding
213035_at	-0.641	7.921	-2.514	2.365e-02	0.299	-3.455	ANKRD28	ankyrin repeat domain 28	3	-15683747	AI081194	23243	3p25.1	Hs.335239	10	protein binding nucleus nucleoplasm
1552418_at	0.357	4.589	2.514	2.366e-02	0.299	-3.455	TTLL10	tubulin tyrosine ligase-like family, member 10	1	1099148, 1104939	NM_153254	254173	1p36.33	Hs.454835	4	tubulin-tyrosine ligase activity cytoplasm cytoskeleton microtubule protein modification process ligase activity protein polyglycylation protein-glycine ligase activity
221712_s_at	-0.352	6.915	-2.513	2.368e-02	0.299	-3.456	WDR74	WD repeat domain 74	11	-62356959	BC006351	54663	11q12.3	Hs.655372	7	molecular_function nucleus nucleolus biological_process
240033_at	0.433	6.080	2.513	2.371e-02	0.299	-3.457	PLG	plasminogen	6	161043263	BF447999	5340	6q26	Hs.143436	198	serine-type endopeptidase activity calcium ion binding extracellular region extracellular region extracellular space proteolysis induction of apoptosis blood coagulation peptidase activity negative regulation of cell proliferation negative regulation of angiogenesis apolipoprotein binding negative regulation of blood vessel endothelial cell migration tissue remodeling negative regulation of fibrinolysis positive regulation of fibrinolysis	Neuroactive ligand-receptor interaction Complement and coagulation cascades
212997_s_at	-0.385	6.715	-2.513	2.372e-02	0.299	-3.458	TLK2	tousled-like kinase 2	17	57910117	AU151689	11011	17q23	Hs.445078	10	nucleotide binding regulation of chromatin assembly or disassembly protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus protein amino acid phosphorylation response to DNA damage stimulus cell cycle intracellular signaling cascade chromatin modification transferase activity
238356_at	0.276	2.791	2.512	2.373e-02	0.299	-3.458	DOCK11	dedicator of cytokinesis 11	X	117513899	AW968823	139818	Xq24	Hs.368203	4	guanyl-nucleotide exchange factor activity GTP binding GTPase binding
213400_s_at	-0.466	6.514	-2.512	2.375e-02	0.299	-3.458	TBL1X	transducin (beta)-like 1X-linked	X	9391334, 9393200	AV753028	6907	Xp22.3	Hs.495656	16	nucleus signal transduction visual perception sensory perception of sound modification-dependent protein catabolic process regulation of transcription	Wnt signaling pathway
213646_x_at	-0.599	10.324	-2.512	2.375e-02	0.299	-3.459	TUBA1B	tubulin, alpha 1b	12	-47807832	BE300252	10376	12q13.12	Hs.524390 Hs.719075	42	nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
215174_at	0.256	3.911	2.512	2.377e-02	0.299	-3.459	FMO6P	flavin containing monooxygenase 6 pseudogene	1	169373502	AL021026	388714	1q24.3	Hs.448988	4	monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction
218757_s_at	-0.443	7.156	-2.511	2.377e-02	0.299	-3.459	UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	X	-118852016	NM_023010	65109	Xq25-q26	Hs.103832	26	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome RNA binding nucleocytoplasmic transporter activity protein binding nucleus cytoplasm transport mRNA transport
209366_x_at	0.349	7.625	2.511	2.378e-02	0.299	-3.460	CYB5A	cytochrome b5 type A (microsomal)	18	-70071506	M22865	1528	18q23	Hs.465413	38	aldo-keto reductase activity cytochrome-c oxidase activity cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum microsome transport membrane integral to membrane heme binding electron transport chain metal ion binding
223051_at	-0.310	9.444	-2.511	2.379e-02	0.299	-3.460	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	AF277178	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
228494_at	-0.590	6.754	-2.511	2.379e-02	0.299	-3.460	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A	7	94374884	AI888150	55607	7q21.3	Hs.21816	12	actin binding protein binding cytoplasm cytoskeleton actin filament organization multicellular organismal development nervous system development synaptosome cell junction cell differentiation filopodium cortical actin cytoskeleton dendritic spine synapse
200991_s_at	-0.500	7.593	-2.511	2.379e-02	0.299	-3.460	SNX17	sorting nexin 17	2	27446892	NM_014748	9784	2p23-p22	Hs.278569	18	receptor binding cytoplasm early endosome Golgi apparatus cholesterol catabolic process intracellular protein transport receptor-mediated endocytosis signal transduction protein C-terminus binding membrane endosome transport regulation of endocytosis phosphoinositide binding low-density lipoprotein receptor binding
1568849_at	0.268	4.289	2.511	2.379e-02	0.299	-3.460	C21orf135	chromosome 21 open reading frame 135	21		BC009635	727701	21q22.3	Hs.382029	2
224600_at	-0.614	6.679	-2.511	2.379e-02	0.299	-3.460	CGGBP1	CGG triplet repeat binding protein 1	3	-88183789	BE501318	8545	3p12-p11.1	Hs.444818	14	DNA binding double-stranded DNA binding nucleus regulation of transcription
208250_s_at	0.256	6.100	2.511	2.379e-02	0.299	-3.460	DMBT1	deleted in malignant brain tumors 1	10	124310170	NM_004406	1755	10q26.13	Hs.279611	60	scavenger receptor activity scavenger receptor activity extracellular region cytoplasm multicellular organismal development pattern recognition receptor activity response to virus protein transport membrane phagocytic vesicle membrane epithelial cell differentiation epithelial cell differentiation induction of bacterial agglutination interspecies interaction between organisms innate immune response calcium-dependent protein binding
233470_at	0.314	5.140	2.511	2.380e-02	0.299	-3.460	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	11	-18706050	U27831	84867	11p15.1	Hs.79092	10	protein tyrosine phosphatase activity protein amino acid dephosphorylation integral to membrane hydrolase activity	MAPK signaling pathway
203757_s_at	0.241	3.672	2.511	2.381e-02	0.299	-3.461	CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	19	46951237	BC005008	4680	19q13.2	Hs.466814	45	plasma membrane plasma membrane integral to plasma membrane signal transduction cell-cell signaling anchored to membrane
205344_at	0.308	5.517	2.511	2.382e-02	0.299	-3.461	CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	3	-47578731	NM_006574	10675	3p21.3	Hs.45127	9	protein binding protein binding membrane fraction endoplasmic reticulum Golgi apparatus plasma membrane integral to plasma membrane multicellular organismal development nervous system development growth factor activity cell differentiation Golgi-associated vesicle membrane regulation of growth intracellular transport
222389_s_at	-0.284	7.428	-2.510	2.383e-02	0.299	-3.462	WAC	WW domain containing adaptor with coiled-coil	10	28861432, 28862429	BE879807	51322		Hs.714700	15	protein binding nucleus nuclear speck
1553167_a_at	-0.485	3.497	-2.509	2.387e-02	0.299	-3.463	SEPSECS	Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase	4	-24730725	BC023539	51091	4p15.2	Hs.253305 Hs.597198	10	tRNA binding selenocysteine incorporation protein binding nucleus cytoplasm translation selenium binding transferase activity selenotransferase activity	Aminoacyl-tRNA biosynthesis
1569905_at	-0.242	5.528	-2.509	2.388e-02	0.299	-3.463	HSD11B1L	hydroxysteroid (11-beta) dehydrogenase 1-like	19	5632034, 5632046, 5632051, 5632074	BC018336	374875	19p13.3	Hs.631840	2	binding extracellular region oxidoreductase activity oxidation reduction
1561041_at	0.255	4.272	2.509	2.388e-02	0.299	-3.464	TNRC6C	trinucleotide repeat containing 6C	17	73511912	BM459591	57690	17q25.3	Hs.569831 Hs.584945	10	nucleotide binding RNA binding regulation of translation gene silencing by RNA
37577_at	0.241	3.649	2.509	2.389e-02	0.299	-3.464	ARHGAP19	Rho GTPase activating protein 19	10	-98971919	U79256	84986	10q24.1	Hs.80305	8	GTPase activator activity intracellular nucleus signal transduction
209498_at	0.323	5.401	2.509	2.389e-02	0.299	-3.464	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	X16354	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
202266_at	-0.389	8.082	-2.509	2.389e-02	0.299	-3.464	TTRAP	TRAF and TNF receptor associated protein	6	-24758183	NM_016614	51567	6p22.3-p22.1	Hs.716397	14	transcription corepressor activity protein binding nucleus cell surface receptor linked signal transduction
223228_at	-0.459	7.426	-2.509	2.389e-02	0.299	-3.464	LDOC1L	leucine zipper, down-regulated in cancer 1-like	22	-43267113	AL136553	84247	22q13.31	Hs.715637	6
215035_at	0.427	4.889	2.509	2.390e-02	0.299	-3.464	IGLV6-57	immunoglobulin lambda variable 6-57	22		AI952772	28778	22q11.2	Hs.535668	6
220018_at	-0.655	4.402	-2.509	2.391e-02	0.299	-3.464	CBLL1	Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1	7	107171514	NM_024814	79872	7q22.3-q31.1	Hs.592271	9	protein binding intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
222561_at	-0.344	7.060	-2.508	2.394e-02	0.300	-3.465	LANCL2	LanC lantibiotic synthetase component C-like 2 (bacterial)	7	55400634	AJ278245	55915	7q31.1-q31.33	Hs.595384 Hs.655117	9	catalytic activity ATP binding GTP binding nucleus cytoplasm cytosol plasma membrane negative regulation of transcription
239192_at	0.272	3.399	2.508	2.394e-02	0.300	-3.466	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	2	205118760	BF434006	117583	2q33.3	Hs.657382	11	protein binding tight junction cell cycle membrane cell junction cell division
211714_x_at	-0.729	9.583	-2.508	2.394e-02	0.300	-3.466	TUBB	tubulin, beta	6	30796135, 2136731, 1935034	BC005838	203068	6p21.33	Hs.636480 Hs.706187 Hs.714425	39	nucleotide binding GTPase activity structural constituent of cytoskeleton GTP binding cytoskeleton microtubule cell motion microtubule-based movement flotillin complex natural killer cell mediated cytotoxicity MHC class I protein binding spindle assembly protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
221487_s_at	-0.859	7.202	-2.508	2.396e-02	0.300	-3.466	ENSA	endosulfine alpha	1	-148866145, -148862377, -148862377, -148861222, -148861222	AF157510	2029	1q21.3	Hs.632456	15	receptor binding cytoplasm transport response to nutrient ion channel inhibitor activity
210317_s_at	-0.448	5.845	-2.507	2.399e-02	0.300	-3.467	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	17	-1194585	U28936	7531	17p13.3	Hs.513851	87	neuron migration cytoplasm mitochondrion protein targeting intracellular signaling cascade enzyme binding protein domain specific binding hippocampus development cerebral cortex development negative regulation of protein amino acid dephosphorylation melanosome interspecies interaction between organisms	Cell cycle Neurotrophin signaling pathway
213624_at	-0.561	8.799	-2.507	2.399e-02	0.300	-3.467	SMPDL3A	sphingomyelin phosphodiesterase, acid-like 3A	6	123151669	AA873600	10924	6q22.31	Hs.486357	5	sphingomyelin phosphodiesterase activity protein binding extracellular region extracellular space sphingomyelin catabolic process metabolic process hydrolase activity, acting on glycosyl bonds
205022_s_at	-0.489	8.479	-2.507	2.400e-02	0.300	-3.468	FOXN3	forkhead box N3	14	-88692268, -88692268	NM_005197	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
238036_at	0.328	4.866	2.507	2.400e-02	0.300	-3.468	SHE	Src homology 2 domain containing E	1	-152718582	AI760776	126669	1q21.3	Hs.591481	5	protein binding
208715_at	-0.254	7.162	-2.506	2.402e-02	0.300	-3.469	TMCO1	transmembrane and coiled-coil domains 1	1	-163960151	BF002031	54499	1q22-q25	Hs.31498 Hs.715707	12	endoplasmic reticulum Golgi apparatus membrane integral to membrane
242157_at	-0.566	4.464	-2.506	2.403e-02	0.300	-3.469	CHD9	chromodomain helicase DNA binding protein 9	16	51646445	AW469037	80205	16q12.2	Hs.59159 Hs.622347	10	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription
213100_at	0.313	5.704	2.506	2.403e-02	0.300	-3.469	UNC5B	unc-5 homolog B (C. elegans)	10	72642303	AA127885	219699	10q22.1	Hs.522997	12	receptor activity protein binding apoptosis signal transduction multicellular organismal development membrane integral to membrane	Axon guidance
238791_at	0.231	3.060	2.506	2.404e-02	0.300	-3.469	ZNF100	zinc finger protein 100	19	-21698682	AA282536	163227	19p12	Hs.365142 Hs.535881	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201090_x_at	-0.585	10.198	-2.506	2.404e-02	0.300	-3.469	TUBA1B	tubulin, alpha 1b	12	-47807832	NM_006082	10376	12q13.12	Hs.524390 Hs.719075	42	nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
203657_s_at	-0.428	7.547	-2.506	2.405e-02	0.300	-3.470	CTSF	cathepsin F	11	-66087510	NM_003793	8722	11q13	Hs.11590	12	cysteine-type endopeptidase activity lysosome proteolysis peptidase activity	Lysosome
204476_s_at	-0.432	5.336	-2.506	2.405e-02	0.300	-3.470	PC	pyruvate carboxylase	11	-66372572, -66372572	NM_022172	5091	11q13.4-q13.5	Hs.89890	26	nucleotide binding pyruvate carboxylase activity pyruvate carboxylase activity ATP binding soluble fraction cytoplasm mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix gluconeogenesis oxaloacetate metabolic process metabolic process lipid biosynthetic process biotin binding ligase activity manganese ion binding carboxylic acid binding metal ion binding	Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways
206295_at	-1.430	4.533	-2.505	2.406e-02	0.300	-3.470	IL18	interleukin 18 (interferon-gamma-inducing factor)	11	-111519185	NM_001562	3606	11q22.2-q22.3	Hs.83077	389	angiogenesis response to hypoxia signal transducer activity cytokine activity interleukin-1 receptor binding extracellular region extracellular space immune response cell-cell signaling response to cold regulation of cell adhesion sleep chemokine biosynthetic process T-helper 1 type immune response T-helper 2 type immune response interleukin-2 biosynthetic process interferon-gamma biosynthetic process positive regulation of activated T cell proliferation interleukin-13 biosynthetic process granulocyte macrophage colony-stimulating factor biosynthetic process	Cytokine-cytokine receptor interaction
200594_x_at	-0.308	9.659	-2.505	2.408e-02	0.300	-3.471	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	NM_004501	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
222693_at	-0.323	3.374	-2.505	2.409e-02	0.300	-3.471	FNDC3B	fibronectin type III domain containing 3B	3	173240111, 173241037	BF444916	64778	3q26.31	Hs.159430	9	endoplasmic reticulum membrane integral to membrane
231132_at	0.276	5.284	2.504	2.412e-02	0.300	-3.472	LOC348120	hypothetical protein LOC348120	15		AW002496	348120	15q11.2	Hs.116287	1
202852_s_at	-0.335	5.190	-2.504	2.412e-02	0.300	-3.472	AAGAB	alpha- and gamma-adaptin binding protein	15	-65280420	NM_024666	79719	15q22.33-q23	Hs.254642	12	cytoplasm protein transport
217249_x_at	0.430	8.979	2.504	2.413e-02	0.300	-3.473	COX7A2	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	6	-76004222	AC004544	1347	6q12	Hs.70312	11	cytochrome-c oxidase activity mitochondrion mitochondrial respiratory chain electron carrier activity membrane	Oxidative phosphorylation Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
238494_at	-0.643	6.661	-2.504	2.413e-02	0.300	-3.473	TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	2	238893923	AI623155	26146	2q37.3	Hs.631898	5	cytoplasm cytoskeleton
221736_at	-0.302	7.053	-2.504	2.413e-02	0.300	-3.473	KIAA1219	KIAA1219	20	36534899	AA156777	57148	20q11.23	Hs.655758	9	GTPase activator activity protein binding intracellular regulation of small GTPase mediated signal transduction
231357_at	0.313	3.699	2.504	2.414e-02	0.300	-3.473	CLEC12B	C-type lectin domain family 12, member B	12	10054497, 10054497	AW003535	387837	12p13.2	Hs.127937	3	receptor activity binding sugar binding plasma membrane integral to membrane
226049_at	-0.240	6.671	-2.503	2.417e-02	0.300	-3.474	ERC1	ELKS/RAB6-interacting/CAST family member 1	12	970664	AI271420	23085	12p13.3	Hs.655744 Hs.658200	19	protein binding cytoplasm Golgi apparatus regulation of transcription, DNA-dependent I-kappaB phosphorylation multicellular organismal development IkappaB kinase complex protein transport Rab GTPase binding retrograde transport, endosome to Golgi presynaptic membrane leucine zipper domain binding positive regulation of anti-apoptosis positive regulation of NF-kappaB transcription factor activity
209661_at	0.369	5.987	2.503	2.417e-02	0.300	-3.474	KIFC3	kinesin family member C3	16	-56349629, -56349629	BC001211	3801	16q13-q21	Hs.23131	10	nucleotide binding microtubule motor activity ATP binding Golgi apparatus kinesin complex microtubule microtubule-based movement Golgi organization visual perception
221516_s_at	0.260	7.080	2.503	2.419e-02	0.300	-3.475	SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	22	38228229	BC002587	54471	22q13	Hs.718449	11	mitochondrion membrane integral to membrane
221994_at	-0.566	12.166	-2.503	2.419e-02	0.300	-3.475	PDLIM5	PDZ and LIM domain 5	4	95592060, 95592060	AA196325	10611	4q22	Hs.480311	34	actin binding protein kinase C binding protein binding membrane fraction cytosol zinc ion binding actin cytoskeleton Z disc actinin binding metal ion binding
208274_at	0.288	4.639	2.503	2.419e-02	0.300	-3.475	OCLM	oculomedin	1	184636326	NM_022375	10896	1q25	Hs.679230	6	visual perception
204821_at	0.445	4.520	2.503	2.420e-02	0.300	-3.475	BTN3A3	butyrophilin, subfamily 3, member A3	6	26548741	NM_006994	10384	6p21.3	Hs.167741	9	membrane integral to membrane
229748_x_at	0.466	6.384	2.501	2.425e-02	0.301	-3.477	LOC100132288	hypothetical protein LOC100132288	21	-103279, -493625	AI380156	100132288	21p11.2	Hs.487562	7
204145_at	-0.327	7.270	-2.501	2.429e-02	0.301	-3.479	FRG1	FSHD region gene 1	4	191098967	NM_004477	2483	4q35	Hs.203772	11	nucleus spliceosomal complex nucleolus rRNA processing mRNA processing RNA splicing Cajal body nuclear speck
1556411_s_at	0.277	4.028	2.500	2.430e-02	0.301	-3.479	KY	kyphoscoliosis peptidase	3	-135801454	AF086360	339855	3q22.2	Hs.146730	4	cytoplasm cytoskeleton peptidase activity
203761_at	0.413	5.123	2.500	2.433e-02	0.301	-3.480	SLA	Src-like-adaptor	8	-134118154, -134118154	NM_006748	6503	8q22.3-qter 8q24	Hs.75367	15	SH3/SH2 adaptor activity protein binding cytoplasm endosome
204332_s_at	-0.555	6.159	-2.500	2.433e-02	0.301	-3.480	AGA	aspartylglucosaminidase	4	-178588917	M64073	175	4q32-q33	Hs.207776	36	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity lysosome protein deglycosylation hydrolase activity protein maturation	Other glycan degradation Lysosome
1560128_x_at	0.325	5.796	2.500	2.434e-02	0.301	-3.480	C5orf56	chromosome 5 open reading frame 56	5	131774571	AL713721	441108	5q31.1	Hs.658288	1
227418_at	-0.699	7.214	-2.499	2.435e-02	0.301	-3.481	KIAA1826	KIAA1826	11	-105383838	AI808746	84437	11q22	Hs.266782	8	nucleus
231299_at	-0.288	4.575	-2.499	2.437e-02	0.301	-3.481	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	7	150414758, 150414758	AI494590	116988	7q36.1	Hs.647075	8	nucleotide binding GTP binding intracellular cytoplasm small GTPase mediated signal transduction ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding
1553517_at	0.354	5.268	2.499	2.437e-02	0.301	-3.482	FERD3L	Fer3-like (Drosophila)	7	-19150929	AF517122	222894	7p21.1	Hs.592168	4	DNA binding nucleus negative regulation of transcription transcription repressor activity
219800_s_at	0.527	3.767	2.499	2.438e-02	0.301	-3.482	THNSL1	threonine synthase-like 1 (S. cerevisiae)	10	25345513	NM_024838	79896	10p12.1	Hs.645274	6	catalytic activity shikimate kinase activity threonine synthase activity ATP binding metabolic process threonine biosynthetic process pyridoxal phosphate binding
1563743_at	0.275	3.552	2.499	2.438e-02	0.301	-3.482	C1orf180	chromosome 1 open reading frame 180	1	-84866500	AK092806	439927	1p22.3	Hs.407054	2
218315_s_at	-0.385	7.100	-2.499	2.439e-02	0.301	-3.482	CDK5RAP1	CDK5 regulatory subunit associated protein 1	20	-31410305	NM_016408	51654	20pter-q11.23	Hs.435952	13	catalytic activity iron ion binding protein binding cellular_component brain development neuronal Cdc2-like kinase binding regulation of neuron differentiation negative regulation of cyclin-dependent protein kinase activity metal ion binding 4 iron, 4 sulfur cluster binding
212833_at	-0.476	8.755	-2.498	2.440e-02	0.301	-3.482	SLC25A46	solute carrier family 25, member 46	5	110102652	M74089	91137	5q22.1	Hs.75639	5	binding cellular_component mitochondrion mitochondrial inner membrane transport biological_process membrane integral to membrane
204545_at	1.010	5.578	2.498	2.440e-02	0.301	-3.483	PEX6	peroxisomal biogenesis factor 6	6	-43039588	NM_000287	5190	6p21.1	Hs.656425	20	nucleotide binding ATP binding cytoplasm peroxisome peroxisomal membrane cytosol protein targeting to peroxisome protein C-terminus binding membrane protein import into peroxisome matrix, translocation protein complex binding ATPase activity, coupled protein stabilization
39582_at	-0.583	6.985	-2.498	2.443e-02	0.301	-3.483	CYLD	cylindromatosis (turban tumor syndrome)	16	49333461, 49333529	AL050166	1540	16q12.1	Hs.578973	54	structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm	RIG-I-like receptor signaling pathway
202905_x_at	-0.457	5.938	-2.498	2.443e-02	0.301	-3.484	NBN	nibrin	8	-91014739	AI796269	4683	8q21	Hs.492208	222	DNA damage checkpoint telomere maintenance nuclear chromosome, telomeric region in utero embryonic development blastocyst growth damaged DNA binding intracellular nucleus nucleoplasm replication fork chromosome nucleolus Golgi apparatus double-strand break repair response to DNA damage stimulus cell cycle cell cycle arrest mitotic cell cycle G2/M transition DNA damage checkpoint meiosis transcription factor binding cell proliferation regulation of DNA replication initiation DNA damage response, signal transduction by p53 class mediator Mre11 complex G1/S transition checkpoint nuclear inclusion body isotype switching protein N-terminus binding regulation of fibroblast proliferation neuromuscular process controlling balance	Homologous recombination
204279_at	0.489	6.795	2.496	2.449e-02	0.302	-3.486	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	6	32929915, 4202792, 4007991	NM_002800	5698	6p21.3	Hs.654585	72	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex immune response peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
225748_at	-0.353	7.010	-2.496	2.450e-02	0.302	-3.486	LTV1	LTV1 homolog (S. cerevisiae)	6	144206200	AI458051	84946	6q24.2	Hs.185675	2
218574_s_at	0.405	10.510	2.496	2.451e-02	0.302	-3.486	LMCD1	LIM and cysteine-rich domains 1	3	8518510	NM_014583	29995	3p26-p24	Hs.475353	4	negative regulation of transcription from RNA polymerase II promoter molecular_function transcription corepressor activity protein binding cellular_component nucleus biological_process zinc ion binding metal ion binding
235590_at	-0.499	4.523	-2.496	2.451e-02	0.302	-3.486	FAM178A	family with sequence similarity 178, member A	10	102662315, 102662315, 102662315	BF112155	55719	10q24.31	Hs.447458	5
240114_s_at	0.312	5.303	2.496	2.452e-02	0.302	-3.487	TMEM174	transmembrane protein 174	5	72504778	AI927971	134288	5q13.2	Hs.508588	3	membrane integral to membrane
210619_s_at	0.917	6.791	2.496	2.453e-02	0.302	-3.487	HYAL1	hyaluronoglucosaminidase 1	3	-50312324, -50312323, -50312323	AF173154	3373	3p21.3-p21.2	Hs.75619	30	hyalurononglucosaminidase activity extracellular region extracellular space lysosome carbohydrate metabolic process metabolic process hydrolase activity, acting on glycosyl bonds glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways
1568713_a_at	-0.625	4.377	-2.495	2.454e-02	0.302	-3.488	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	AI872403	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
219076_s_at	0.413	7.807	2.495	2.455e-02	0.302	-3.488	PXMP2	peroxisomal membrane protein 2, 22kDa	12	131774264	NM_018663	5827	12q24.33	Hs.430299	5	protein binding peroxisome membrane integral to membrane
201353_s_at	0.331	5.617	2.495	2.455e-02	0.302	-3.488	BAZ2A	bromodomain adjacent to zinc finger domain, 2A	12	-55275646	AI653126	11176	12q24.3-qter	Hs.314263	11	chromatin silencing at rDNA DNA binding RNA binding protein binding nucleus chromatin silencing complex nucleolus nucleolus organizer region DNA methylation chromatin remodeling regulation of transcription, DNA-dependent zinc ion binding histone deacetylation transcription regulator activity rDNA heterochromatin metal ion binding histone acetyl-lysine binding
1553007_a_at	0.337	4.446	2.495	2.456e-02	0.302	-3.488	ODZ1	odz, odd Oz/ten-m homolog 1(Drosophila)	X	-123337436	NM_014253	10178	Xq25	Hs.23796 Hs.537002 Hs.716649	13	extracellular region integral to plasma membrane immune response signal transduction nervous system development heparin binding negative regulation of cell proliferation membrane
200829_x_at	-0.366	8.477	-2.495	2.456e-02	0.302	-3.488	ZNF207	zinc finger protein 207	17	27701269	NM_003457	7756	17q11.2	Hs.500775	7	transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204674_at	0.313	6.129	2.495	2.457e-02	0.302	-3.489	LRMP	lymphoid-restricted membrane protein	12	25096507	NM_006152	4033	12p12.1	Hs.124922	9	cytoplasm endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane vesicle targeting vesicle fusion membrane
230010_at	0.350	4.608	2.495	2.458e-02	0.302	-3.489	KIAA1853	KIAA1853	12	117903778	AA608629	84530	12q24.23	Hs.112577	4
222470_s_at	-0.583	5.467	-2.494	2.461e-02	0.303	-3.490	UQCC	ubiquinol-cytochrome c reductase complex chaperone	20	-33353794	AA033998	55245	20q11.22	Hs.714359	16	cytoplasmic vesicle
1555697_at	0.307	6.924	2.494	2.463e-02	0.303	-3.491	KLK4	kallikrein-related peptidase 4	19	-56101419	AF259970	9622	19q13.41	Hs.218366	34	serine-type endopeptidase activity extracellular region proteolysis peptidase activity zinc ion binding metal ion binding
208816_x_at	-0.399	8.124	-2.493	2.464e-02	0.303	-3.491	ANXA2P2	annexin A2 pseudogene 2	9	33614222	M62898	304	9p13	Hs.534301	2	angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm
212239_at	-0.617	7.454	-2.493	2.467e-02	0.303	-3.492	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	5	67558217, 67620007, 67622250	AI680192	5295	5q13.1	Hs.132225 Hs.604502	321	negative regulation of cell-matrix adhesion insulin receptor binding insulin-like growth factor receptor binding phosphatidylinositol binding intracellular cytosol cytosol 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex protein amino acid phosphorylation signal transduction insulin receptor signaling pathway phosphoinositide 3-kinase cascade membrane protein phosphatase binding B cell differentiation positive regulation of cell migration phosphoinositide 3-kinase regulator activity negative regulation of apoptosis ErbB-3 class receptor binding insulin binding insulin receptor substrate binding interspecies interaction between organisms negative regulation of osteoclast differentiation positive regulation of glucose import phosphoinositide phosphorylation insulin-like growth factor receptor signaling pathway growth hormone receptor signaling pathway regulation of establishment of protein localization	ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
226774_at	-0.387	6.073	-2.493	2.467e-02	0.303	-3.492	FAM120B	family with sequence similarity 120B	6	170457768	N48188	84498	6q27	Hs.369522	7	protein binding nucleus cell differentiation regulation of transcription
1563607_x_at	-0.239	4.532	-2.493	2.468e-02	0.303	-3.493	hCG_2045089	hypothetical LOC286359	9	-99192941	AL833510	286359	9q22.33	Hs.132262	2
205013_s_at	0.314	5.128	2.492	2.469e-02	0.303	-3.493	ADORA2A	adenosine A2a receptor	22	23153529	NM_000675	135	22q11.23	Hs.197029	109	adenosine receptor activity, G-protein coupled receptor activity G-protein coupled receptor activity membrane fraction plasma membrane integral to plasma membrane cAMP biosynthetic process phagocytosis apoptosis inflammatory response cellular defense response signal transduction transmembrane receptor protein tyrosine kinase signaling pathway G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger activation of adenylate cyclase activity cell-cell signaling central nervous system development blood coagulation sensory perception blood circulation	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
217644_s_at	-0.700	4.807	-2.492	2.469e-02	0.303	-3.493	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	AI276593	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
222414_at	-0.421	7.217	-2.492	2.469e-02	0.303	-3.493	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	7	-151462942	AA121529	58508	7q36.1	Hs.647120	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent intracellular signaling cascade methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
212410_at	-0.406	9.692	-2.492	2.471e-02	0.303	-3.494	EFHA1	EF-hand domain family, member A1	13	-20964838	AI346431	221154	13q12.11	Hs.412103	7	calcium ion binding
227394_at	-0.604	5.756	-2.491	2.473e-02	0.303	-3.495	NCAM1	neural cell adhesion molecule 1	11	112337204, 112337204	W94001	4684	11q23.1	Hs.503878	120	protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane	Cell adhesion molecules (CAMs) Prion diseases
208843_s_at	-0.318	8.512	-2.491	2.474e-02	0.303	-3.495	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	BC001408	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
226334_s_at	-0.354	6.675	-2.491	2.475e-02	0.303	-3.495	AHSA2	AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)	2	61258324	AW117717	130872	2p15	Hs.655602	6	ATPase activator activity cytoplasm response to stress chaperone binding
204696_s_at	0.257	5.147	2.491	2.476e-02	0.303	-3.495	CDC25A	cell division cycle 25 homolog A (S. pombe)	3	-48173671	NM_001789	993	3p21	Hs.437705	89	regulation of cyclin-dependent protein kinase activity protein tyrosine phosphatase activity protein binding cellular_component intracellular nucleoplasm DNA replication protein amino acid dephosphorylation cell cycle mitosis cell proliferation hydrolase activity cell division	Cell cycle
1556377_s_at	-0.509	5.956	-2.491	2.478e-02	0.303	-3.496	LMO7	LIM domain 7	13	75092570, 75232797	AF174600	4008	13q22.2	Hs.207631	18	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm zinc ion binding protein ubiquitination metal ion binding	Adherens junction
236253_at	0.282	4.419	2.491	2.478e-02	0.303	-3.496	ZNF546	zinc finger protein 546	19	45194782	BE548749	339327	19q13.2	Hs.709400	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213918_s_at	-0.357	5.516	-2.490	2.479e-02	0.303	-3.496	NIPBL	Nipped-B homolog (Drosophila)	5	36912617	BF221673	25836	5p13.2	Hs.481927	22	protein binding nucleus cell cycle cohesin loading complex maintenance of mitotic sister chromatid cohesion
226549_at	0.342	7.461	2.490	2.479e-02	0.303	-3.497	SBK1	SH3-binding domain kinase 1	16	28211340	BF447901	388228	16p11.2	Hs.97837	3	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
212804_s_at	-0.411	5.990	-2.490	2.480e-02	0.303	-3.497	GAPVD1	GTPase activating protein and VPS9 domains 1	9	127063931	AI797397	26130	9q33.3	Hs.495134	9	guanyl-nucleotide exchange factor activity GTPase activator activity intracellular endosome cytosol endocytosis signal transduction membrane GTPase activating protein binding regulation of small GTPase mediated signal transduction regulation of protein transport
222532_at	-0.487	6.304	-2.490	2.480e-02	0.303	-3.497	SRPRB	signal recognition particle receptor, B subunit	3	135007366	BF983948	58477	3q22.1	Hs.12152	10	nucleotide binding receptor activity protein binding GTP binding endoplasmic reticulum membrane integral to membrane ribonucleoprotein complex
226801_s_at	-0.333	8.894	-2.490	2.482e-02	0.303	-3.498	AIDA	axin interactor, dorsalization associated	1	-220907977	W72220	64853	1q41	Hs.156625 Hs.534965 Hs.707666	6	protein binding cellular_component multicellular organismal development dorsal/ventral pattern formation regulation of protein homodimerization activity negative regulation of JNK cascade
213085_s_at	0.254	5.414	2.489	2.485e-02	0.304	-3.499	WWC1	WW and C2 domain containing 1	5	167651642	AB020676	23286	5q34	Hs.484047	19	protein binding cytoplasm
214587_at	0.218	2.318	2.489	2.486e-02	0.304	-3.499	COL8A1	collagen, type VIII, alpha 1	3	100840143	BE877796	1295	3q12.3	Hs.654548	16	protein binding extracellular region collagen type VIII basement membrane cell adhesion positive regulation of cell-substrate adhesion camera-type eye morphogenesis epithelial cell proliferation
209732_at	-0.895	7.902	-2.489	2.487e-02	0.304	-3.500	CLEC2B	C-type lectin domain family 2, member B	12	-9896234	BC005254	9976	12p13-p12	Hs.85201	10	binding sugar binding integral to plasma membrane membrane
200710_at	0.448	11.429	2.489	2.487e-02	0.304	-3.500	ACADVL	acyl-Coenzyme A dehydrogenase, very long chain	17	7063876	NM_000018	37	17p13-p11	Hs.437178 Hs.463928	30	long-chain-acyl-CoA dehydrogenase activity mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation electron carrier activity energy derivation by oxidation of organic compounds membrane mitochondrial nucleoid FAD binding oxidation reduction	Fatty acid metabolism Metabolic pathways
204160_s_at	-0.586	7.255	-2.489	2.488e-02	0.304	-3.500	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)	6	46205659	AW194947	22875	6p21.1	Hs.643497	4	metabolic process membrane integral to membrane hydrolase activity
212947_at	-0.404	5.960	-2.489	2.488e-02	0.304	-3.500	SLC9A8	solute carrier family 9 (sodium/hydrogen exchanger), member 8	20	47862656	AL031685	23315	20q13.13	Hs.444202	12	Golgi apparatus cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane sodium ion binding
229772_at	0.289	5.237	2.489	2.488e-02	0.304	-3.500	DEFB123	defensin, beta 123	20	29492071	AA789269	245936	20q11.1	Hs.122509	4	extracellular region defense response to bacterium
231741_at	0.323	5.631	2.488	2.488e-02	0.304	-3.500	S1PR3	sphingosine-1-phosphate receptor 3	9	90796181	NM_005226	1903	9q22.1-q22.2	Hs.585118	31	lysosphingolipid and lysophosphatidic acid receptor activity cytokine production receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane inflammatory response signal transduction G-protein coupled receptor protein signaling pathway inhibition of adenylate cyclase activity by G-protein signaling elevation of cytosolic calcium ion concentration positive regulation of cell proliferation lipid binding anatomical structure morphogenesis regulation of interleukin-1 beta production	Neuroactive ligand-receptor interaction
214034_at	-0.571	4.271	-2.488	2.489e-02	0.304	-3.500	ERAP1	endoplasmic reticulum aminopeptidase 1	5	-96135943, -96122269	AB011097	51752	5q15	Hs.716426	40	aminopeptidase activity interleukin-6 receptor binding interleukin-1, Type II receptor binding protein binding extracellular region cytoplasm endoplasmic reticulum endoplasmic reticulum lumen cytosol proteolysis membrane protein ectodomain proteolysis immune response regulation of blood pressure peptidase activity metalloexopeptidase activity zinc ion binding response to bacterium membrane integral to membrane antigen processing and presentation of endogenous peptide antigen via MHC class I regulation of innate immune response fat cell differentiation positive regulation of angiogenesis metal ion binding
216708_x_at	0.384	3.339	2.488	2.490e-02	0.304	-3.501	IGL@	immunoglobulin lambda locus	22		D84143	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
220003_at	0.213	5.856	2.488	2.491e-02	0.304	-3.501	LRRC36	leucine rich repeat containing 36	16	65918247, 65938758	NM_018296	55282	16q22.1	Hs.125139	3	protein binding
1557480_a_at	-0.632	9.889	-2.487	2.495e-02	0.304	-3.502	DYSFIP1	dysferlin interacting protein 1	17	-77384656	AI972007	116729	17q25.3	Hs.454720	5
200760_s_at	-0.479	10.202	-2.487	2.495e-02	0.304	-3.502	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	3	69216779	N92494	10550	3p14	Hs.518060 Hs.716493	30	protein binding cytoplasm endoplasmic reticulum L-glutamate transport membrane integral to membrane
207648_at	0.420	5.522	2.487	2.495e-02	0.304	-3.502	DRP2	dystrophin related protein 2	X	100361588	NM_001939	1821	Xq22	Hs.159291	13	calcium ion binding protein binding membrane fraction cytoplasm cytoskeleton plasma membrane central nervous system development zinc ion binding dendrite synapse organization
212109_at	-0.261	5.582	-2.487	2.496e-02	0.304	-3.503	HN1L	hematological and neurological expressed 1-like	16	1668278	AI590869	90861	16p13.3	Hs.513261	8	nucleus cytoplasm
220358_at	0.231	5.589	2.487	2.497e-02	0.304	-3.503	BATF3	basic leucine zipper transcription factor, ATF-like 3	1	-210926381	NM_018664	55509	1q32.3	Hs.62919	7	transcription factor activity transcription corepressor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity
1569616_at	0.271	3.835	2.487	2.497e-02	0.304	-3.503	LOC647309	hypothetical protein LOC647309	3	-192053219	BC031680	647309	3q28	Hs.518490	1
1554633_a_at	-0.255	3.768	-2.487	2.497e-02	0.304	-3.503	MYT1L	myelin transcription factor 1-like	2	-1771891	AF036943	23040	2p25.3	Hs.434418 Hs.669852	7	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development nervous system development zinc ion binding cell differentiation metal ion binding
206690_at	0.284	4.003	2.486	2.500e-02	0.304	-3.504	ACCN1	amiloride-sensitive cation channel 1, neuronal	17	-28364218, -28364218	NM_001094	40	17q12	Hs.368417	18	ion channel activity protein binding plasma membrane integral to plasma membrane ion transport sodium ion transport synaptic transmission central nervous system development peripheral nervous system development amiloride-sensitive sodium channel activity sodium ion binding	Taste transduction
223299_at	0.310	7.028	2.486	2.502e-02	0.304	-3.505	SEC11C	SEC11 homolog C (S. cerevisiae)	18	54958104	AF212233	90701	18q21.32	Hs.45107	2	endoplasmic reticulum microsome signal peptide processing proteolysis peptidase activity membrane integral to membrane	Protein export
219419_at	-0.386	6.838	-2.486	2.502e-02	0.304	-3.505	C18orf22	chromosome 18 open reading frame 22	18	75895345	NM_024805	79863	18q23	Hs.593610	3	mitochondrion rRNA processing
217946_s_at	-0.491	7.029	-2.485	2.503e-02	0.304	-3.505	SAE1	SUMO1 activating enzyme subunit 1	19	52325919, 52325954, 52325971	NM_016402	10055	19q13.32	Hs.515500	20	ubiquitin activating enzyme activity nucleus protein modification process protein C-terminus binding protein C-terminus binding enzyme activator activity metabolic process protein ubiquitination ligase activity modification-dependent protein catabolic process ATP-dependent protein binding protein heterodimerization activity	Ubiquitin mediated proteolysis
213578_at	-0.367	6.972	-2.485	2.503e-02	0.304	-3.505	BMPR1A	bone morphogenetic protein receptor, type IA	10	88506375	AI678679	657	10q22.3	Hs.524477	70	nucleotide binding magnesium ion binding mesoderm formation Mullerian duct regression positive regulation of mesenchymal cell proliferation protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity ATP binding plasma membrane plasma membrane caveola protein amino acid phosphorylation immune response transforming growth factor beta receptor signaling pathway pattern specification process ectoderm development heart development dorsal/ventral axis specification anterior/posterior pattern formation positive regulation of pathway-restricted SMAD protein phosphorylation integral to membrane transferase activity stem cell maintenance manganese ion binding cell differentiation lung development positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway hindlimb morphogenesis odontogenesis of dentine-containing tooth protein homodimerization activity positive regulation of osteoblast differentiation SMAD binding mesendoderm development embryonic morphogenesis positive regulation of epithelial cell proliferation negative regulation of neurogenesis cartilage development palate development positive regulation of SMAD protein nuclear translocation	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
90265_at	0.277	7.023	2.485	2.505e-02	0.304	-3.506	ADAP1	ArfGAP with dual PH domains 1	7	-904062	AW050627	11033	7p22.3	Hs.644629	22	protein binding nucleus cytoplasm plasma membrane cell surface receptor linked signal transduction ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity regulation of GTPase activity inositol 1,3,4,5 tetrakisphosphate binding metal ion binding
218369_s_at	0.297	3.468	2.485	2.506e-02	0.304	-3.506	EXOSC1	exosome component 1	10	-99185655	NM_016046	51013	10q24	Hs.632089	14	exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus rRNA processing hydrolase activity	RNA degradation
224077_at	0.282	2.711	2.484	2.509e-02	0.305	-3.507	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	8	-38293091, -38251717	AF255649	54904	8p11.2	Hs.700599	10	protein binding nucleus nucleus nucleolus mitochondrion methyltransferase activity zinc ion binding cell growth chromatin modification histone methylation transferase activity histone-lysine N-methyltransferase activity cell differentiation regulation of transcription metal ion binding	Lysine degradation
222199_s_at	-0.331	5.260	-2.484	2.510e-02	0.305	-3.508	BIN3	bridging integrator 3	8	-22533891	AK001289	55909	8p21.3	Hs.718405	10	cytokinesis barrier septum formation protein binding cytoplasm cytoskeleton actin filament organization cell cycle cytoskeletal adaptor activity protein localization protein localization unidimensional cell growth unidimensional cell growth
1552347_at	-0.387	6.518	-2.484	2.511e-02	0.305	-3.508	CRYZL1	crystallin, zeta (quinone reductase)-like 1	21	-33883517	NM_145311	9946	21q21.3	Hs.352671	9	NADPH:quinone reductase activity binding cytosol zinc ion binding oxidoreductase activity quinone cofactor metabolic process NADP or NADPH binding oxidation reduction
210995_s_at	-0.547	4.580	-2.484	2.511e-02	0.305	-3.508	TRIM23	tripartite motif-containing 23	5	-64921262	AF230399	373	5q12.3	Hs.792	14	Golgi membrane nucleotide binding GTPase activity ubiquitin-protein ligase activity protein binding GTP binding intracellular nucleus cytoplasm lysosomal membrane Golgi apparatus small GTPase mediated signal transduction enzyme activator activity zinc ion binding membrane protein ubiquitination GDP binding metal ion binding
238842_at	0.308	5.950	2.484	2.511e-02	0.305	-3.508	C10orf12	chromosome 10 open reading frame 12	10	98731030	BE000242	26148	10q24.1	Hs.14555 Hs.427927	5
222421_at	-0.385	8.212	-2.483	2.513e-02	0.305	-3.509	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	7	-129260230	BF435617	7328	7q32	Hs.643548	16	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity regulation of protein metabolic process	Ubiquitin mediated proteolysis
1564514_at	0.234	3.982	2.483	2.513e-02	0.305	-3.509	SNRK	SNF related kinase	3	43303007	AK098414	54861	3p22.1	Hs.476052	14	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation transferase activity myeloid cell differentiation
210829_s_at	-0.484	6.766	-2.483	2.515e-02	0.305	-3.509	SSBP2	single-stranded DNA binding protein 2	5	-80751427	AF077048	23635	5q14.1	Hs.102735	14	DNA binding single-stranded DNA binding protein binding nucleus cytoplasm transcription regulator activity regulation of transcription
218125_s_at	-0.425	6.953	-2.483	2.515e-02	0.305	-3.509	CCDC25	coiled-coil domain containing 25	8	-27646751	NM_018246	55246	8p21.1	Hs.445512	6
221872_at	0.515	3.695	2.482	2.520e-02	0.305	-3.511	RARRES1	retinoic acid receptor responder (tazarotene induced) 1	3	-159905133, -159897590	AI669229	5918	3q25.32	Hs.131269	11	negative regulation of cell proliferation membrane integral to membrane
209727_at	0.262	6.185	2.482	2.521e-02	0.305	-3.512	GM2A	GM2 ganglioside activator	5	150612805	M76477	2760	5q31.3-q33.1	Hs.483873	32	lipid transporter activity cytoplasm mitochondrion lysosome hydrogen:potassium-exchanging ATPase complex lipid metabolic process ganglioside catabolic process lipid transport learning or memory oligosaccharide catabolic process internal side of plasma membrane phospholipase activator activity glycolipid catabolic process lipid storage sphingolipid catabolic process sphingolipid activator protein activity beta-N-acetylgalactosaminidase activity apical cortex neurological system process neuromuscular process controlling balance positive regulation of hydrolase activity	Lysosome
207067_s_at	0.240	4.696	2.482	2.522e-02	0.305	-3.512	HDC	histidine decarboxylase	15	-48321437	NM_002112	3067	15q21-q22	Hs.1481	37	histidine decarboxylase activity cellular amino acid and derivative metabolic process histidine metabolic process lyase activity carboxylic acid metabolic process pyridoxal phosphate binding catecholamine biosynthetic process	Histidine metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
235343_at	-0.831	3.146	-2.482	2.522e-02	0.305	-3.512	VASH2	vasohibin 2	1	211190509	AI961235	79805	1q32.3	Hs.96885	5
223314_at	0.354	5.831	2.482	2.522e-02	0.305	-3.512	TSPAN14	tetraspanin 14	10	82204017	BF025955	81619	10q23.1	Hs.310453	5	membrane integral to membrane
222103_at	-0.558	8.706	-2.482	2.523e-02	0.305	-3.512	ATF1	activating transcription factor 1	12	49444085	AI434345	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
219353_at	-0.476	7.093	-2.481	2.525e-02	0.305	-3.513	NHLRC2	NHL repeat containing 2	10	115604409	NM_017687	374354	10q25.3	Hs.369924 Hs.594372	2	cell redox homeostasis
225475_at	-0.394	5.946	-2.481	2.526e-02	0.305	-3.513	MIER1	mesoderm induction early response 1 homolog (Xenopus laevis)	1	67163165, 67168513	AI668786	57708	1p31.3	Hs.652983	14	DNA binding signal transducer activity nucleus cytoplasm positive regulation of I-kappaB kinase/NF-kappaB cascade regulation of transcription
235542_at	-0.322	4.632	-2.480	2.528e-02	0.306	-3.514	TET3	tet oncogene family member 3	2	74126957	BF675754	200424	2p13.1	Hs.516107	6	iron ion binding oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors metal ion binding oxidation reduction
234993_at	-0.320	3.074	-2.480	2.529e-02	0.306	-3.514	ABHD13	abhydrolase domain containing 13	13	107668763	BE301702	84945	13q33.3	Hs.183528	6	membrane integral to membrane hydrolase activity
1553234_at	0.215	4.780	2.480	2.530e-02	0.306	-3.515	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	16	-75873525	NM_139054	170692	16q23	Hs.188746	9	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
202679_at	-0.488	5.584	-2.479	2.533e-02	0.306	-3.516	NPC1	Niemann-Pick disease, type C1	18	-19365462	NM_000271	4864	18q11-q12	Hs.464779 Hs.715623	61	protein binding nuclear envelope lysosome endosome endoplasmic reticulum integral to plasma membrane endocytosis lysosomal transport hedgehog receptor activity bile acid metabolic process sterol transporter activity membrane negative regulation of macroautophagy cholesterol efflux cholesterol homeostasis cholesterol homeostasis response to cadmium ion perinuclear region of cytoplasm	Lysosome
225726_s_at	0.755	5.398	2.479	2.533e-02	0.306	-3.516	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	14	67069760	AB033026	57475	14q24.1	Hs.594236	4	binding cytoskeleton
230196_x_at	0.294	5.909	2.479	2.533e-02	0.306	-3.516	ARHGAP23	Rho GTPase activating protein 23	17	33867169	AI123323	57636	17q12	Hs.374446	4	GTPase activator activity protein binding intracellular signal transduction
1560472_at	0.273	5.328	2.479	2.534e-02	0.306	-3.516	LOC338588	hypothetical LOC338588	10	4688347	BC040895	338588	10p15.1	Hs.121365	1
1558249_s_at	-0.516	5.476	-2.479	2.535e-02	0.306	-3.516	STX16	syntaxin 16	20	56659733, 56659733	BE878126	8675	20q13.32	Hs.307913	14	SNAP receptor activity cytoplasm microsome Golgi apparatus intracellular protein transport intra-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport SNARE complex retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
1555547_at	0.305	2.046	2.479	2.537e-02	0.306	-3.517	BPA-1	brain peptide A1	1		AB088847	100131534	1p31.3	Hs.684094
202130_at	-0.333	9.842	-2.479	2.537e-02	0.306	-3.517	RIOK3	RIO kinase 3 (yeast)	18	19286784	AA725102	8780	18q11.2	Hs.445511 Hs.719109	9	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation chromosome segregation kinase activity transferase activity
206123_at	0.420	7.438	2.479	2.537e-02	0.306	-3.517	LLGL1	lethal giant larvae homolog 1 (Drosophila)	17	18069660	D50550	3996	17p11.2	Hs.513983	14	structural molecule activity protein binding cytoplasm cytoskeleton protein complex assembly exocytosis protein kinase binding cortical actin cytoskeleton cortical actin cytoskeleton organization maintenance of apical/basal cell polarity	Tight junction
204234_s_at	-0.506	5.164	-2.478	2.540e-02	0.306	-3.518	ZNF195	zinc finger protein 195	11	-3336586	AI476267	7748	11p15.5	Hs.386294	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214015_at	0.305	4.071	2.478	2.540e-02	0.306	-3.518	SOCS7	suppressor of cytokine signaling 7	17	33761530	AI968839	30837	17q12	Hs.514132 Hs.632261	16	protein binding cellular_component cytoplasm plasma membrane intracellular signaling cascade biological_process insulin receptor signaling pathway negative regulation of signal transduction protein ubiquitination SH3 domain binding modification-dependent protein catabolic process regulation of growth fat cell differentiation	Jak-STAT signaling pathway
1559244_at	0.269	3.914	2.478	2.541e-02	0.306	-3.519	FMN2	formin 2	1	238321807	AF218941	56776	1q43	Hs.24889	7	molecular_function actin binding cellular_component meiotic metaphase I multicellular organismal development cellular component organization meiotic chromosome movement towards spindle pole actin cytoskeleton organization polar body extrusion after meiotic divisions oogenesis establishment of meiotic spindle localization	Dorso-ventral axis formation
201087_at	-0.334	7.223	-2.478	2.542e-02	0.306	-3.519	PXN	paxillin	12	-119132632, -119132632	NM_002859	5829	12q24.31	Hs.446336	140	protein binding cytoplasm cytoskeleton microtubule associated complex plasma membrane focal adhesion cell adhesion cell-matrix adhesion signal transduction signal complex assembly zinc ion binding vinculin binding lamellipodium cell junction cellular response to reactive oxygen species metal ion binding	Chemokine signaling pathway VEGF signaling pathway Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
203389_at	0.264	5.823	2.478	2.542e-02	0.306	-3.519	KIF3C	kinesin family member 3C	2	-26002958	AF035621	3797	2p23	Hs.21611	9	nucleotide binding microtubule motor activity ATP binding kinesin complex microtubule microtubule-based movement
225006_x_at	0.346	7.495	2.478	2.542e-02	0.306	-3.519	TH1L	TH1-like (Drosophila)	20	56989705	AJ238379	51497	20q13	Hs.517148	22	protein binding nucleus nucleoplasm negative regulation of transcription
221376_at	0.323	5.608	2.478	2.542e-02	0.306	-3.519	FGF17	fibroblast growth factor 17	8	21956373	NM_003867	8822	8p21	Hs.248192	17	extracellular region extracellular region extracellular space signal transduction cell-cell signaling nervous system development growth factor activity positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
209758_s_at	-1.221	7.000	-2.477	2.544e-02	0.306	-3.520	MFAP5	microfibrillar associated protein 5	12	-8689806	U37283	8076	12p13.1-p12.3	Hs.512842	9	microfibril extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix
243618_s_at	0.365	8.093	2.477	2.545e-02	0.306	-3.520	ZNF827	zinc finger protein 827	4	-146901337	BF678830	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212930_at	-0.580	6.527	-2.477	2.546e-02	0.306	-3.520	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	12	-88505956	AW576457	490	12q21.3	Hs.506276	38	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
1554077_a_at	0.364	5.760	2.477	2.546e-02	0.306	-3.520	TMEM53	transmembrane protein 53	1	-44892087	BC007521	79639	1p34.1	Hs.22157	5	Golgi apparatus plasma membrane focal adhesion integral to membrane
205526_s_at	-0.391	7.173	-2.477	2.547e-02	0.306	-3.521	KATNA1	katanin p60 (ATPase-containing) subunit A 1	6	-149957864	NM_007044	11104	6q25.1	Hs.450175	12	nucleotide binding spindle pole ATP binding cytoplasm centrosome microtubule cell cycle mitosis microtubule binding microtubule-severing ATPase activity hydrolase activity nucleoside-triphosphatase activity protein heterodimerization activity cell division interphase of mitotic cell cycle
225146_at	-0.386	7.079	-2.477	2.547e-02	0.306	-3.521	C9orf25	chromosome 9 open reading frame 25	9	-34388181	AW005237	203259	9p13.3	Hs.493771	8
1553583_a_at	0.429	5.731	2.477	2.548e-02	0.306	-3.521	THRSP	thyroid hormone responsive (SPOT14 homolog, rat)	11	77452554	NM_003251	7069	11q13.5	Hs.591969	12	protein binding nucleus lipid metabolic process
229018_at	-0.501	6.469	-2.476	2.548e-02	0.306	-3.521	C12orf26	chromosome 12 open reading frame 26	12	81276454	AI310001	84190	12q21.31	Hs.506222	3
210321_at	0.384	4.655	2.475	2.554e-02	0.307	-3.523	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	14	-24145532	M36118	2999	14q11.2	Hs.348264	17	serine-type endopeptidase activity cytoplasm proteolysis apoptosis peptidase activity cytolysis
224641_at	-0.505	9.844	-2.475	2.557e-02	0.307	-3.524	FYTTD1	forty-two-three domain containing 1	3	198960820, 198961020, 198961657	BF576005	84248	3q29	Hs.277533	6
224897_at	-0.394	8.752	-2.474	2.558e-02	0.307	-3.524	WDR26	WD repeat domain 26	1	-222639467	BF510490	80232	1q42.11-q42.12	Hs.497873	8	cytoplasm
232172_at	-0.293	4.887	-2.474	2.559e-02	0.307	-3.525	LOC401577	hypothetical protein LOC401577	X, Y		AK023533	401577	Xp22.33 Yp11.31	Hs.444541	2
225853_at	-0.489	7.011	-2.474	2.560e-02	0.307	-3.525	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1	14	-52311660	BE789346	64841	14q22.1	Hs.702056	5	glucosamine 6-phosphate N-acetyltransferase activity late endosome ER-Golgi intermediate compartment Golgi apparatus metabolic process acyltransferase activity membrane transferase activity	Amino sugar and nucleotide sugar metabolism
222142_at	-0.506	3.687	-2.474	2.560e-02	0.307	-3.525	CYLD	cylindromatosis (turban tumor syndrome)	16	49333461, 49333529	AK024212	1540	16q12.1	Hs.578973	54	structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm	RIG-I-like receptor signaling pathway
212919_at	-0.716	6.631	-2.474	2.561e-02	0.307	-3.525	DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)	5	112340331	AV715578	167227	5q22.2	Hs.443875	21	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasmic mRNA processing body RNA binding protein binding nucleus cytoplasm hydrolase activity manganese ion binding metal ion binding	RNA degradation
220896_at	0.246	5.006	2.473	2.565e-02	0.307	-3.527	FBXL18	F-box and leucine-rich repeat protein 18	7	-5481953	NM_024963	80028	7p22.2	Hs.623974 Hs.706587	5	modification-dependent protein catabolic process
202754_at	-0.482	8.357	-2.473	2.565e-02	0.307	-3.527	R3HDM1	R3H domain containing 1	2	136005552	NM_015361	23518	2q21.3	Hs.412462	8	nucleic acid binding
211249_at	0.288	4.295	2.473	2.566e-02	0.307	-3.527	GPR68	G protein-coupled receptor 68	14	-90768628	U35398	8111	14q31	Hs.8882	14	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane inflammatory response signal transduction G-protein coupled receptor protein signaling pathway
222468_at	-0.294	7.535	-2.473	2.567e-02	0.307	-3.528	KIAA0319L	KIAA0319-like	1	-35671678	W58365	79932	1p34.2	Hs.456507	4	membrane integral to membrane
1569677_a_at	0.244	2.454	2.473	2.568e-02	0.307	-3.528	C8orf45	chromosome 8 open reading frame 45	8	67945537, 67945537, 67946290	BC034576	157777	8q13.1	Hs.437006	2
209323_at	-0.385	8.357	-2.472	2.569e-02	0.307	-3.528	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	11	-75738651	AF081567	5612	11q13.5	Hs.503315	12	DNA binding nucleus nucleolus response to stress signal transduction zinc ion binding negative regulation of cell proliferation metal ion binding protein dimerization activity
227118_s_at	0.272	4.432	2.472	2.571e-02	0.307	-3.529	MRPS26	mitochondrial ribosomal protein S26	20	2974674	AA594308	64949	20p13	Hs.18946	10	mitochondrion mitochondrial small ribosomal subunit ribosome DNA damage response, detection of DNA damage peptide biosynthetic process
209612_s_at	0.778	7.063	2.472	2.571e-02	0.307	-3.529	ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	4	-100446549	M24317	125	4q21-q23	Hs.4	193	alcohol dehydrogenase (NAD) activity binding cytoplasm ethanol oxidation zinc ion binding oxidoreductase activity metal ion binding oxidation reduction	Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
208471_at	-0.388	4.720	-2.472	2.572e-02	0.307	-3.529	HPR	haptoglobin-related protein	16	70654625	NM_020995	3250	16q22.1	Hs.655361	17	catalytic activity serine-type endopeptidase activity extracellular region proteolysis hemoglobin binding spherical high-density lipoprotein particle
1553166_at	0.299	4.883	2.472	2.573e-02	0.307	-3.530	CDH24	cadherin-like 24	14	-22586109	NM_144985	64403	14q11.2	Hs.155912	4	calcium ion binding protein binding plasma membrane cell-cell junction homophilic cell adhesion integral to membrane
224703_at	-0.370	7.580	-2.471	2.574e-02	0.307	-3.530	DCAF5	DDB1 and CUL4 associated factor 5	14	-68587390	AI814644	8816	14q23-q24.1	Hs.509780	6
214285_at	0.940	9.920	2.471	2.574e-02	0.307	-3.530	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)	1	-31610686	AI041520	2170	1p33-p32	Hs.657242	35	transporter activity cytoplasm phosphatidylcholine biosynthetic process transport negative regulation of cell proliferation lipid binding	PPAR signaling pathway
228833_s_at	0.283	3.670	2.471	2.575e-02	0.307	-3.530	LOC400027	hypothetical protein LOC400027	12		BE963456	400027	12q12	Hs.597122	1
223288_at	-0.881	8.835	-2.471	2.575e-02	0.307	-3.530	USP38	ubiquitin specific peptidase 38	4	144325519	AW977401	84640		Hs.480848	7	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
1563321_s_at	0.352	4.279	2.471	2.576e-02	0.307	-3.531	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10	21863107, 21863579	AF272384	8028	10p12	Hs.30385	19	transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding
204294_at	0.340	7.196	2.470	2.579e-02	0.308	-3.532	AMT	aminomethyltransferase	3	-49429214	NM_000481	275	3p21.2-p21.1	Hs.102	17	aminomethyltransferase activity cytoplasm mitochondrion glycine catabolic process transaminase activity transferase activity	Glycine, serine and threonine metabolism One carbon pool by folate Nitrogen metabolism Metabolic pathways
222457_s_at	-0.580	6.726	-2.470	2.580e-02	0.308	-3.532	LIMA1	LIM domain and actin binding 1	12	-48855829, -48855829	BC001247	51474	12q13	Hs.525419	23	stress fiber actin monomer binding cytoplasm focal adhesion zinc ion binding actin cytoskeleton cell junction negative regulation of actin filament depolymerization ruffle organization metal ion binding actin filament binding actin filament bundle formation
204028_s_at	-0.359	8.424	-2.470	2.581e-02	0.308	-3.532	RABGAP1	RAB GTPase activating protein 1	9	124743108	NM_012197	23637	9q33.2-q33.3	Hs.271341	6	GTPase activator activity Rab GTPase activator activity intracellular cytoplasm centrosome cytosol microtubule associated complex cell cycle tubulin binding regulation of Rab GTPase activity
53987_at	-0.239	5.906	-2.470	2.581e-02	0.308	-3.532	RANBP10	RAN binding protein 10	16	-66314505	AL041852	57610	16q22.1	Hs.368569	8	microtubule cytoskeleton organization Ran guanyl-nucleotide exchange factor activity cytoplasm cytoplasmic microtubule Ran GTPase binding beta-tubulin binding
212442_s_at	-0.650	6.656	-2.470	2.582e-02	0.308	-3.533	LASS6	LAG1 homolog, ceramide synthase 6	2	169021080	BG289001	253782	2q24.3	Hs.506829 Hs.718403	5	transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding ceramide biosynthetic process sphingosine N-acyltransferase activity
235508_at	0.288	5.918	2.469	2.587e-02	0.308	-3.534	PML	promyelocytic leukemia	15	72074066, 72074066, 72074066	AW291023	5371	15q22	Hs.526464	208	response to hypoxia DNA binding intracellular insoluble fraction nucleus nucleoplasm nucleolus cytoplasm protein complex assembly induction of apoptosis activation of caspase activity DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest cell cycle arrest transforming growth factor beta receptor signaling pathway common-partner SMAD protein phosphorylation SMAD protein nuclear translocation cell aging zinc ion binding negative regulation of cell proliferation response to UV response to gamma radiation nuclear matrix negative regulation of transcription negative regulation of angiogenesis PML body myeloid cell differentiation negative regulation of cell growth transcription regulator activity PML body organization ubiquitin protein ligase binding nuclear membrane response to cytokine stimulus DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis protein homodimerization activity interspecies interaction between organisms regulation of MHC class I biosynthetic process SMAD binding metal ion binding retinoic acid receptor signaling pathway maintenance of protein location in nucleus	Ubiquitin mediated proteolysis Pathways in cancer Acute myeloid leukemia
233842_x_at	-0.340	8.632	-2.469	2.587e-02	0.308	-3.534	C20orf43	chromosome 20 open reading frame 43	20	54477053	AK000586	51507	20q13.31	Hs.517134	10	molecular_function cellular_component biological_process
214545_s_at	-0.406	7.165	-2.469	2.588e-02	0.308	-3.535	PROSC	proline synthetase co-transcribed homolog (bacterial)	8	37739258	NM_007198	11212	8p11.2	Hs.304792 Hs.608177	8	intracellular cytoplasm
228950_s_at	-0.548	4.267	-2.468	2.591e-02	0.308	-3.536	GPR177	G protein-coupled receptor 177	1	-68363628, -68336738	AL534095	79971	1p31.3	Hs.647659	8	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
203524_s_at	0.477	7.661	2.468	2.593e-02	0.309	-3.536	MPST	mercaptopyruvate sulfurtransferase	22	35745647	NM_021126	4357	22q13.1	Hs.248267	9	thiosulfate sulfurtransferase activity cytoplasm mitochondrion sulfate transport cyanate catabolic process response to toxin transferase activity 3-mercaptopyruvate sulfurtransferase activity	Cysteine and methionine metabolism Metabolic pathways
201074_at	-0.413	6.544	-2.467	2.594e-02	0.309	-3.537	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	3	-47602381	AA593983	6599	3p23-p21	Hs.476179	39	chromatin DNA binding chromatin binding transcription coactivator activity intracellular nucleus nucleoplasm chromatin assembly or disassembly chromatin remodeling regulation of transcription from RNA polymerase II promoter protein C-terminus binding organ morphogenesis SWI/SNF complex regulation of transcription positive regulation of transcription, DNA-dependent protein N-terminus binding
211758_x_at	-0.327	8.078	-2.467	2.595e-02	0.309	-3.537	TXNDC9	thioredoxin domain containing 9	2	-99301918	BC005968	10190	2q11.2	Hs.536122	8	protein binding cellular_component biological_process
214620_x_at	-0.510	7.799	-2.467	2.595e-02	0.309	-3.537	PAM	peptidylglycine alpha-amidating monooxygenase	5	102229425	BF038548	5066	5q14-q21	Hs.369430	34	monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding protein binding extracellular region protein modification process peptide metabolic process zinc ion binding cellular process membrane integral to membrane lyase activity secretory granule L-ascorbic acid binding metal ion binding oxidation reduction
1569879_a_at	0.244	6.234	2.467	2.595e-02	0.309	-3.537	MEGF11	multiple EGF-like-domains 11	15	-63974687	BC029999	84465	15q22.31	Hs.712886	6	plasma membrane integral to membrane
231948_s_at	-0.367	7.718	-2.467	2.597e-02	0.309	-3.538	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	2	238540438	BG171548	140739	2q37.3	Hs.471785	4	nucleotide binding protein binding ATP binding ligase activity NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation regulation of protein metabolic process	Ubiquitin mediated proteolysis
209113_s_at	-0.353	5.518	-2.467	2.597e-02	0.309	-3.538	HMG20B	high-mobility group 20B	19	3523942	AF288679	10362	19p13.3	Hs.406534	18	transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle chromatin modification
241729_at	-0.289	3.747	-2.467	2.597e-02	0.309	-3.538	DOK6	docking protein 6	18	65219270	AW173080	220164	18q22.2	Hs.278285	4	insulin receptor binding
202963_at	-0.444	6.095	-2.467	2.599e-02	0.309	-3.538	RFX5	regulatory factor X, 5 (influences HLA class II expression)	1	-149579739	AW027312	5993	1q21	Hs.632472	27	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent	Antigen processing and presentation Primary immunodeficiency
238577_s_at	0.337	2.850	2.466	2.601e-02	0.309	-3.539	TSHZ2	teashirt zinc finger homeobox 2	20	51022283	AA628481	128553	20q13.2	Hs.271605 Hs.473117 Hs.649877	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding
203069_at	0.273	4.775	2.466	2.602e-02	0.309	-3.540	SV2A	synaptic vesicle glycoprotein 2A	1	-148141499	NM_014849	9900	1q21.2	Hs.516153	24	transporter activity cytoplasm endoplasmic reticulum neurotransmitter transport membrane integral to membrane cell junction cytoplasmic vesicle synapse	ECM-receptor interaction
231930_at	-0.644	4.562	-2.466	2.603e-02	0.309	-3.540	ELMOD1	ELMO/CED-12 domain containing 1	11	106967026	AL359601	55531	11q22.3	Hs.495779	5	cytoskeleton phagocytosis
225344_at	0.420	6.390	2.466	2.604e-02	0.309	-3.540	NCOA7	nuclear receptor coactivator 7	6	126153693	AL035689	135112	6q22.32	Hs.171426	18	protein binding intracellular nucleus cell wall macromolecule catabolic process regulation of transcription
204306_s_at	-0.424	7.177	-2.465	2.604e-02	0.309	-3.540	CD151	CD151 molecule (Raph blood group)	11	822951	NM_004357	977	11p15.5	Hs.654379	55	protein binding membrane fraction plasma membrane integral to plasma membrane cell adhesion
1555595_at	-0.292	3.001	-2.465	2.605e-02	0.309	-3.541	SCRN3	secernin 3	2	174968712	BC007344	79634	2q31.1	Hs.470679	7
226588_at	-0.389	5.799	-2.465	2.606e-02	0.309	-3.541	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	2	-180517848	AB046824	57703	2q31.3	Hs.311363	6	RNA binding protein binding nucleus spliceosomal complex mRNA processing RNA splicing RNA metabolic process regulation of nuclear mRNA splicing, via spliceosome
1552280_at	0.311	3.795	2.465	2.607e-02	0.309	-3.541	TIMD4	T-cell immunoglobulin and mucin domain containing 4	5	-156278870	NM_138379	91937	5q33.3	Hs.334907	11	membrane integral to membrane
225200_at	-0.830	7.822	-2.464	2.610e-02	0.309	-3.542	DPH3	DPH3, KTI11 homolog (S. cerevisiae)	3	-16273572	AU151106	285381	3p25.1	Hs.388087	8	protein binding nucleus cytoplasm zinc ion binding peptidyl-diphthamide biosynthetic process from peptidyl-histidine metal ion binding negative regulation of protein secretion positive regulation of binding
1558945_s_at	0.237	1.984	2.464	2.613e-02	0.309	-3.543	CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	19	-13178256	BC042451	773	19p13.2-p13.1	Hs.501632	126	voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity calcium ion binding protein binding nucleus cytoplasm plasma membrane plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport elevation of cytosolic calcium ion concentration cell death integral to membrane syntaxin binding cell projection	MAPK signaling pathway Calcium signaling pathway Long-term depression Taste transduction Type II diabetes mellitus
1567628_at	0.295	4.600	2.463	2.614e-02	0.309	-3.544	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	5	-149761394, -149761392	M28590	972	5q32	Hs.436568	58	prostaglandin biosynthetic process intracellular protein complex assembly intracellular protein transport immune response signal transduction cell proliferation membrane integral to membrane immunoglobulin mediated immune response antigen processing and presentation of endogenous antigen cytokine binding MHC class II protein binding identical protein binding regulation of macrophage activation negative regulation of apoptosis T cell selection	Antigen processing and presentation
201392_s_at	-0.495	8.226	-2.463	2.615e-02	0.309	-3.544	IGF2R	insulin-like growth factor 2 receptor	6	160310120	BG031974	3482	6q26	Hs.487062	101	glycoprotein binding receptor activity insulin-like growth factor receptor activity transporter activity insulin-like growth factor binding mannose binding membrane fraction nucleus nuclear envelope lumen cytoplasm lysosome endosome Golgi apparatus integral to plasma membrane transport receptor-mediated endocytosis signal transduction membrane trans-Golgi network transport vesicle	Lysosome
228608_at	0.487	3.211	2.463	2.615e-02	0.309	-3.544	NALCN	sodium leak channel, non-selective	13	-100504130	N49852	259232	13q32.3	Hs.525146	8	voltage-gated ion channel activity sodium channel activity ion transport sodium ion transport membrane integral to membrane sodium ion binding
227642_at	-0.737	4.545	-2.463	2.615e-02	0.309	-3.544	TFCP2L1	transcription factor CP2-like 1	2	-121690635	AI928242	29842	2q14	Hs.156471	8	negative regulation of transcription from RNA polymerase II promoter cell morphogenesis epithelial cell maturation transcription factor activity transcription corepressor activity nucleus cytoplasm steroid biosynthetic process cytoplasm organization salivary gland development female pregnancy determination of adult lifespan membrane general transcriptional repressor activity regulation of transcription positive regulation of growth
214043_at	-0.562	3.829	-2.463	2.617e-02	0.309	-3.545	PTPRD	protein tyrosine phosphatase, receptor type, D	9	-8304245	BF062299	5789	9p23-p24.3	Hs.446083	23	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine phosphatase signaling pathway membrane hydrolase activity
228236_at	0.245	5.613	2.463	2.617e-02	0.309	-3.545	C20orf54	chromosome 20 open reading frame 54	20	-688723	AA903862	113278	20p13	Hs.283865	6	membrane integral to membrane
235257_at	0.302	5.607	2.463	2.617e-02	0.309	-3.545	ODF3B	outer dense fiber of sperm tails 3B	22	-49315703	BF436372	440836	22q13.33	Hs.531314	6
238263_at	0.265	4.063	2.463	2.618e-02	0.309	-3.545	LOC285965	hypothetical protein LOC285965	7		AW590543	285965	7q35	Hs.642649
209531_at	-0.356	7.331	-2.463	2.618e-02	0.309	-3.545	GSTZ1	glutathione transferase zeta 1	14	76856982, 76857458	BC001453	2954	14q24.3	Hs.655292	31	glutathione transferase activity glutathione peroxidase activity protein binding cytoplasm mitochondrion cytosol L-phenylalanine catabolic process tyrosine catabolic process aromatic amino acid family metabolic process maleylacetoacetate isomerase activity maleylacetoacetate isomerase activity transferase activity isomerase activity	Tyrosine metabolism Glutathione metabolism Styrene degradation Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
242838_at	-0.487	5.515	-2.463	2.619e-02	0.309	-3.545	MAP6D1	MAP6 domain containing 1	3	-185016357	AA283642	79929	3q27.1	Hs.478465	4	calmodulin binding cytoplasm Golgi apparatus Golgi-associated vesicle cis-Golgi network cytoskeleton negative regulation of microtubule depolymerization microtubule binding N-terminal peptidyl-L-cysteine N-palmitoylation
212260_at	-0.397	6.622	-2.462	2.619e-02	0.309	-3.546	GIGYF2	GRB10 interacting GYF protein 2	2	233270258	AL045800	26058	2q37.1	Hs.565319	23	protein binding
225340_s_at	-0.392	7.527	-2.462	2.620e-02	0.309	-3.546	CAPRIN1	cell cycle associated protein 1	11	34029805, 34029805	BG107845	4076	11p13	Hs.471818	10	protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection
217997_at	-0.416	3.562	-2.462	2.621e-02	0.309	-3.546	PHLDA1	pleckstrin homology-like domain, family A, member 1	12	-74705493	AI795908	22822	12q15	Hs.602085	15	protein binding nucleus nucleolus cytoplasm apoptosis membrane cytoplasmic vesicle membrane cytoplasmic vesicle FasL biosynthetic process
219505_at	0.541	6.139	2.462	2.622e-02	0.309	-3.546	CECR1	cat eye syndrome chromosome region, candidate 1	22	-16040193, -16040191	NM_017424	51816	22q11.2	Hs.170310	10	extracellular region extracellular space Golgi apparatus multicellular organismal development growth factor activity purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity
227137_at	0.345	3.105	2.462	2.622e-02	0.309	-3.547	C10orf46	chromosome 10 open reading frame 46	10	-120430483	N25937	143384	10q26.11	Hs.719193	4	ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding
238171_at	0.301	4.024	2.462	2.624e-02	0.309	-3.547	SLC25A30	solute carrier family 25, member 30	13	-44865455	AI128486	253512	13q14.13	Hs.591230	3	binding mitochondrion mitochondrial inner membrane transport mitochondrial transport membrane integral to membrane
225474_at	0.617	5.455	2.462	2.624e-02	0.309	-3.547	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	3	-65319983, -65314945	AI141556	9223	3p14.1	Hs.651939	24	nucleotide binding ATP binding plasma membrane cell-cell junction tight junction protein complex assembly cell adhesion cell surface receptor linked signal transduction protein C-terminus binding	Tight junction
227282_at	0.356	4.869	2.460	2.633e-02	0.310	-3.550	PCDH19	protocadherin 19	X	-99433297	AB037734	57526	Xq13.3	Hs.4993	12	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
202683_s_at	-0.414	6.322	-2.460	2.633e-02	0.310	-3.550	RNMT	RNA (guanine-7-) methyltransferase	18	13716703	NM_003799	8731	18p11.22-p11.23	Hs.592347	13	RNA binding mRNA (guanine-N7-)-methyltransferase activity mRNA (guanine-N7-)-methyltransferase activity nucleus nucleoplasm mRNA capping methyltransferase activity transferase activity
202207_at	1.091	4.276	2.460	2.633e-02	0.310	-3.550	ARL4C	ADP-ribosylation factor-like 4C	2	-235066424	BG435404	10123	2q37.1	Hs.111554 Hs.719190	7	nucleotide binding GTPase activity GTP binding intracellular nucleus small GTPase mediated signal transduction
218773_s_at	0.269	10.273	2.460	2.633e-02	0.310	-3.550	MSRB2	methionine sulfoxide reductase B2	10	23424432	NM_012228	22921	10p12	Hs.461420	14	protein-methionine-R-oxide reductase activity transcription factor activity mitochondrion peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity protein repair metal ion binding oxidation reduction
237373_at	0.218	3.485	2.460	2.634e-02	0.310	-3.550	RAB20	RAB20, member RAS oncogene family	13	-109973413	BE464359	55647	13q34	Hs.719403	7	nucleotide binding GTP binding Golgi apparatus small GTPase mediated signal transduction protein transport
230938_x_at	0.328	7.105	2.459	2.635e-02	0.310	-3.551	ATF5	activating transcription factor 5	19	55123785	H48515	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
236171_at	0.263	4.870	2.459	2.636e-02	0.310	-3.551	ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	16	82959633	BE219325	9914	16q24.1	Hs.6168	6	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding ATP binding ATP biosynthetic process cation transport calcium ion transport metabolic process membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
220449_at	0.234	5.908	2.459	2.637e-02	0.310	-3.551	MGC5566	hypothetical protein MGC5566	20		NM_024049	79015	20q13.12	Hs.255479	1
226562_at	-0.379	6.800	-2.459	2.637e-02	0.310	-3.551	ZSCAN29	zinc finger and SCAN domain containing 29	15	-41437661	BE622486	146050	15q15.3	Hs.418287	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
AFFX-HUMISGF3A/M97935_MA_at	0.243	5.781	2.459	2.640e-02	0.310	-3.552	STAT1	signal transducer and activator of transcription 1, 91kDa	2	-191548507, -191542006	AFFX-HUMISGF3A/M97935_MA	6772	2q32.2	Hs.642990 Hs.715518	323	transcription factor activity signal transducer activity hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity calcium ion binding protein binding nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter activation of caspase activity signal transduction I-kappaB kinase/NF-kappaB cascade tyrosine phosphorylation of STAT protein response to virus interspecies interaction between organisms	Chemokine signaling pathway Toll-like receptor signaling pathway Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer
224513_s_at	-0.315	7.096	-2.458	2.640e-02	0.310	-3.553	UBQLN4	ubiquilin 4	1	-154271715	BC006410	56893	1q21	Hs.283739	9	nucleus cytoplasm endoplasmic reticulum endoplasmic reticulum membrane cytosol biological_process identical protein binding
205438_at	-0.250	4.659	-2.458	2.641e-02	0.310	-3.553	PTPN21	protein tyrosine phosphatase, non-receptor type 21	14	-88001874	NM_007039	11099	14q31.3	Hs.437040	10	protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity
200790_at	-0.637	9.208	-2.458	2.642e-02	0.310	-3.553	ODC1	ornithine decarboxylase 1	2	-10497958	NM_002539	4953	2p25	Hs.467701	47	kidney development ornithine decarboxylase activity protein binding cellular_component cytosol polyamine biosynthetic process positive regulation of cell proliferation lyase activity	Arginine and proline metabolism Glutathione metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
209546_s_at	0.310	6.253	2.458	2.644e-02	0.310	-3.554	APOL1	apolipoprotein L, 1	22	34979062	AF323540	8542	22q13.1	Hs.114309	27	chloride channel activity protein binding extracellular region extracellular space lipid metabolic process chloride transport lipid transport steroid metabolic process cholesterol metabolic process lipid binding cytolysis intrinsic to membrane killing of cells of another organism very-low-density lipoprotein particle high-density lipoprotein particle lipoprotein metabolic process innate immune response
211197_s_at	0.230	5.329	2.458	2.645e-02	0.310	-3.554	ICOSLG	inducible T-cell co-stimulator ligand	21	-44471149	AL355690	23308	21q22.3	Hs.14155	29	receptor binding defense response immune response hyperosmotic response signal transduction membrane integral to membrane positive regulation of activated T cell proliferation T cell activation B cell activation	Cell adhesion molecules (CAMs)
212871_at	-0.532	5.925	-2.458	2.645e-02	0.310	-3.554	MAPKAPK5	mitogen-activated protein kinase-activated protein kinase 5	12	110764661	NM_003668	8550	12q24.12-q24.13	Hs.413901	16	nucleotide binding protein serine/threonine kinase activity MAP kinase kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction transferase activity	MAPK signaling pathway
201722_s_at	-0.557	8.042	-2.457	2.647e-02	0.310	-3.555	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	AV692127	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
206010_at	0.391	4.744	2.457	2.647e-02	0.310	-3.555	HABP2	hyaluronan binding protein 2	10	115302767	NM_004132	3026	10q25.3	Hs.422542	30	serine-type endopeptidase activity glycosaminoglycan binding extracellular region extracellular space proteolysis cell adhesion peptidase activity
217743_s_at	-0.457	6.162	-2.457	2.647e-02	0.310	-3.555	TMEM30A	transmembrane protein 30A	6	-76019357	NM_018247	55754	6q14.1	Hs.108530	7	membrane integral to membrane
227235_at	0.328	6.520	2.457	2.648e-02	0.310	-3.555	GUCY1A3	guanylate cyclase 1, soluble, alpha 3	4	156807311, 156807311, 156807311, 156807598, 156807598, 156808264	AI758408	2982	4q31.1-q31.2 4q31.3-q33	Hs.24258	14	nucleotide binding guanylate cyclase activity receptor activity GTP binding cytoplasm nitric oxide mediated signal transduction guanylate cyclase complex, soluble regulation of blood pressure positive regulation of cGMP biosynthetic process response to defense-related host nitric oxide production relaxation of vascular smooth muscle	Purine metabolism Vascular smooth muscle contraction Gap junction Long-term depression
32091_at	-0.288	6.740	-2.457	2.648e-02	0.310	-3.555	SLC25A44	solute carrier family 25, member 44	1	154430353	AB007915	9673	1q22	Hs.532375	6	transporter activity binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
203097_s_at	-0.339	8.111	-2.457	2.649e-02	0.310	-3.555	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	4	160408447	NM_014247	9693	4q32.1	Hs.113912	14	MAPKKK cascade signal transducer activity guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular plasma membrane integral to plasma membrane Rap guanyl-nucleotide exchange factor activity cAMP-mediated signaling diacylglycerol binding Rap GTPase activator activity regulation of small GTPase mediated signal transduction	MAPK signaling pathway
215294_s_at	-0.488	4.844	-2.457	2.649e-02	0.310	-3.556	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	X	-128408158	AK026426	6594	Xq25	Hs.152292	15	nucleotide binding DNA binding helicase activity protein binding ATP binding nucleus brain development DNA-dependent ATPase activity chromatin remodeling complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides neuron differentiation transcription regulator activity nucleosome binding ATP-dependent chromatin remodeling positive regulation of gene-specific transcription regulation of transcription
235226_at	0.359	3.022	2.457	2.650e-02	0.310	-3.556	CDC2L6	cell division cycle 2-like 6 (CDK8-like)	6	-111037873	AA994004	23097	6q21	Hs.719138	10	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
226026_at	-0.556	7.505	-2.456	2.651e-02	0.310	-3.556	DIRC2	disrupted in renal carcinoma 2	3	123996590	AI147467	84925	3q21.1	Hs.477346	7	transport membrane integral to membrane
204620_s_at	-0.587	5.836	-2.456	2.651e-02	0.310	-3.556	VCAN	versican	5	82803248	NM_004385	1462	5q14.3	Hs.643801 Hs.715773	74	binding calcium ion binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development cell recognition	Cell adhesion molecules (CAMs)
221927_s_at	0.344	7.441	2.456	2.653e-02	0.310	-3.557	ABHD11	abhydrolase domain containing 11	7	-72789980, -72789935, -72788362, -72788362	AI923458	83451	7q11.23	Hs.647045	9	molecular_function cellular_component biological_process hydrolase activity
213574_s_at	-0.431	8.607	-2.456	2.655e-02	0.311	-3.558	KPNB1	karyopherin (importin) beta 1	17	43082273	AA861608	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
223629_at	-0.406	4.087	-2.456	2.655e-02	0.311	-3.558	PCDHB5	protocadherin beta 5	5	140494983	BC001186	26167	5q31	Hs.119693	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion synaptic transmission synaptogenesis integral to membrane calcium-dependent cell-cell adhesion
201274_at	-0.254	8.803	-2.455	2.657e-02	0.311	-3.558	PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	1	-109745994	NM_002790	5686	1p13	Hs.712557	45	threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
202295_s_at	0.439	7.350	2.455	2.657e-02	0.311	-3.558	CTSH	cathepsin H	15	-77001146	NM_004390	1512	15q24-q25	Hs.148641	34	cysteine-type endopeptidase activity protein binding lysosome endoplasmic reticulum proteolysis peptidase activity	Lysosome
209055_s_at	-0.556	6.170	-2.455	2.658e-02	0.311	-3.559	CDC5L	CDC5 cell division cycle 5-like (S. pombe)	6	44463279	AW268817	988	6p21	Hs.485471	35	DNA binding RNA binding protein binding nucleus spliceosomal complex nucleolus cytoplasm regulation of transcription, DNA-dependent mRNA processing cell cycle RNA splicing nuclear speck
242396_at	0.351	3.868	2.454	2.661e-02	0.311	-3.560	LOC100132798	similar to hCG1774772	15		AA195408	100132798	15q26.2
222661_at	-0.359	7.006	-2.454	2.662e-02	0.311	-3.560	AGGF1	angiogenic factor with G patch and FHA domains 1	5	76361987	AA528017	55109	5q13.3	Hs.634849	12	vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm
224664_at	-0.278	10.834	-2.453	2.666e-02	0.311	-3.561	C10orf104	chromosome 10 open reading frame 104	10	73645811	BE962336	119504	10q22.1	Hs.426296	5
214670_at	-0.496	5.726	-2.453	2.668e-02	0.311	-3.562	ZKSCAN1	zinc finger with KRAB and SCAN domains 1	7	99451154	AA653300	7586	7q21.3-q22.1	Hs.615360	11	transcription factor activity intracellular nucleus cytoplasm mitochondrion regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210029_at	0.554	6.979	2.453	2.669e-02	0.311	-3.562	IDO1	indoleamine 2,3-dioxygenase 1	8	39890484	M34455	3620	8p12-p11	Hs.840	105	positive regulation of T cell tolerance induction positive regulation of chronic inflammatory response positive regulation of T-helper 2 type immune response tryptophan 2,3-dioxygenase activity tryptophan 2,3-dioxygenase activity cytoplasm cytosol female pregnancy electron carrier activity oxidoreductase activity tryptophan catabolic process to kynurenine NAD metabolic process heme binding indoleamine 2,3-dioxygenase activity metal ion binding oxidation reduction	Tryptophan metabolism Metabolic pathways
1554555_a_at	-0.458	6.387	-2.453	2.669e-02	0.311	-3.562	SETD6	SET domain containing 6	16	57106883	BC022451	79918	16q21	Hs.592060	5
226856_at	-0.868	11.844	-2.453	2.670e-02	0.311	-3.562	MUSTN1	musculoskeletal, embryonic nuclear protein 1	3	-52842176	BF793701	389125	3p21.1	Hs.556077	1	nucleus
222327_x_at	0.455	5.425	2.453	2.670e-02	0.311	-3.562	OR7E156P	olfactory receptor, family 7, subfamily E, member 156 pseudogene	13	63209568	AA459867	283491	13q21.31	Hs.363054 Hs.694575	2
234464_s_at	-0.335	4.366	-2.453	2.671e-02	0.311	-3.563	EME1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	17	45805588	AK021607	146956	17q21.33	Hs.514330	15	magnesium ion binding DNA binding endonuclease activity protein binding nucleus nucleolus DNA repair DNA recombination response to DNA damage stimulus hydrolase activity	Homologous recombination
228788_at	-0.662	4.036	-2.453	2.671e-02	0.311	-3.563	YPEL1	yippee-like 1 (Drosophila)	22	-20381825	AA425358	29799	22q11.2	Hs.517436	7	nucleus
203373_at	0.621	4.920	2.452	2.673e-02	0.311	-3.563	SOCS2	suppressor of cytokine signaling 2	12	92487728	NM_003877	8835	12q	Hs.485572	40	regulation of cell growth SH3/SH2 adaptor activity growth hormone receptor binding prolactin receptor binding insulin-like growth factor receptor binding protein binding cytoplasm anti-apoptosis intracellular signaling cascade JAK-STAT cascade JAK pathway signal transduction adaptor activity negative regulation of signal transduction modification-dependent protein catabolic process response to estradiol stimulus growth hormone receptor signaling pathway	Jak-STAT signaling pathway Insulin signaling pathway Type II diabetes mellitus
1570383_at	0.249	3.704	2.452	2.674e-02	0.311	-3.564	BMP1	bone morphogenetic protein 1	8	22078619, 22078619	AF289591	649	8p21.3	Hs.1274	38	cartilage condensation ossification metalloendopeptidase activity cytokine activity calcium ion binding extracellular space proteolysis multicellular organismal development growth factor activity peptidase activity zinc ion binding cell differentiation
219239_s_at	-0.487	5.272	-2.452	2.674e-02	0.311	-3.564	ZNF654	zinc finger protein 654	3	88270951	NM_018293	55279	3p11.1	Hs.591650 Hs.661116	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1553603_s_at	-0.501	4.235	-2.452	2.676e-02	0.311	-3.564	ATL2	atlastin GTPase 2	2	-38375534	NM_022374	64225	2p22.2-p22.1	Hs.594950	8	nucleotide binding GTPase activity GTP binding membrane integral to membrane
205838_at	0.291	3.646	2.451	2.677e-02	0.312	-3.565	GYPA	glycophorin A (MNS blood group)	4	-145249905	NM_002099	2993	4q28.2-q31.1	Hs.434973	60	membrane fraction plasma membrane integral to membrane identical protein binding	Hematopoietic cell lineage
225184_at	-0.329	5.435	-2.451	2.677e-02	0.312	-3.565	ARID1B	AT rich interactive domain 1B (SWI1-like)	6	157140777	AK000921	57492	6q25.1	Hs.291587 Hs.714899	22	DNA binding DNA binding transcription coactivator activity protein binding intracellular nucleus nucleolus cytoplasm SWI/SNF complex chromatin modification regulation of transcription chromatin-mediated maintenance of transcription
209846_s_at	0.590	6.032	2.451	2.680e-02	0.312	-3.566	BTN3A2	butyrophilin, subfamily 3, member A2	6	26473376	BC002832	11118	6p22.1	Hs.376046	9	biological_process membrane integral to membrane
219204_s_at	-0.683	4.806	-2.451	2.681e-02	0.312	-3.566	SRR	serine racemase	17	2153997	NM_021947	63826	17p13	Hs.461954	22	calcium ion binding protein binding ATP binding cellular amino acid metabolic process L-serine metabolic process metabolic process glycine binding isomerase activity racemase and epimerase activity, acting on amino acids and derivatives threonine racemase activity pyridoxal phosphate binding serine racemase activity protein homodimerization activity protein homotetramerization D-serine biosynthetic process	Glycine, serine and threonine metabolism
221884_at	0.405	5.524	2.450	2.684e-02	0.312	-3.567	MECOM	MDS1 and EVI1 complex locus	3	-170283980, -170283980, -170283980, -170283980	BE466525	2122	3q24-q28	Hs.659873 Hs.719216	46	molecular_function DNA binding transcription factor activity protein binding intracellular nucleus multicellular organismal development biological_process zinc ion binding metal ion binding	MAPK signaling pathway Pathways in cancer Chronic myeloid leukemia
231879_at	-0.444	4.156	-2.450	2.684e-02	0.312	-3.567	COL12A1	collagen, type XII, alpha 1	6	-75850761	AL096771	1303	6q12-q13	Hs.101302	19	skeletal system development structural molecule activity protein binding extracellular region proteinaceous extracellular matrix collagen type XII cell adhesion extracellular matrix structural constituent conferring tensile strength collagen fibril organization
235367_at	-0.658	8.917	-2.450	2.684e-02	0.312	-3.567	MYPN	myopalladin	10	69539255	BF109970	84665	10q21.3	Hs.55205	12	actin binding nucleus cytoplasm sarcomere
210175_at	-0.422	6.860	-2.450	2.684e-02	0.312	-3.567	C2orf3	chromosome 2 open reading frame 3	2	-75742801	BC000853	6936	2p11.2-p11.1	Hs.303808 Hs.662279	13	transcription factor activity protein binding nucleus regulation of transcription
1553061_at	0.362	4.621	2.450	2.685e-02	0.312	-3.568	OR6W1P	olfactory receptor, family 6, subfamily W, member 1 pseudogene	7	-142469502	NM_033519	89883	7q34	Hs.339818	2
203618_at	0.259	5.620	2.450	2.686e-02	0.312	-3.568	FAIM2	Fas apoptotic inhibitory molecule 2	12	-48546946	AB023167	23017	12q13	Hs.567424	9	protein binding plasma membrane apoptosis anti-apoptosis integral to membrane cell junction synapse postsynaptic membrane
232636_at	-1.743	4.987	-2.450	2.687e-02	0.312	-3.568	SLITRK4	SLIT and NTRK-like family, member 4	X	-142543607	AL080239	139065	Xq27.3	Hs.272284	4	protein binding axonogenesis membrane integral to membrane
244556_at	0.326	4.273	2.449	2.688e-02	0.312	-3.569	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	5	-169607665	AI824014	3937	5q33.1-qter	Hs.304475	72	protein binding cytoplasm cytosol immune response transmembrane receptor protein tyrosine kinase signaling pathway mast cell activation cytokine secretion	Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway
229528_at	-0.222	6.630	-2.448	2.693e-02	0.312	-3.570	LOC283378	hypothetical protein LOC283378	12		AI670935	283378	12q24.31	Hs.594149	1
1556474_a_at	-0.291	2.496	-2.448	2.694e-02	0.312	-3.570	FLJ38379	hypothetical FLJ38379	2		AK095698	285097	2q37.3	Hs.653239	1
231759_at	-0.538	6.621	-2.448	2.694e-02	0.312	-3.570	TAL2	T-cell acute lymphocytic leukemia 2	9	107464558	NM_005421	6887	9q32	Hs.247978	9	DNA binding protein binding nucleus behavior post-embryonic development thalamus development transcription regulator activity midbrain development multicellular organism growth regulation of transcription
211276_at	0.288	3.057	2.448	2.695e-02	0.312	-3.571	TCEAL2	transcription elongation factor A (SII)-like 2	X	101267315	AF063606	140597	Xq22.1-q22.3	Hs.401835	6	nucleus regulation of transcription
221252_s_at	0.252	3.807	2.448	2.697e-02	0.312	-3.571	GSG1	germ cell associated 1	12	-13128308, -13128308	NM_031289	83445	12p13.1	Hs.240053	7	endoplasmic reticulum membrane integral to membrane
227728_at	-0.426	9.606	-2.447	2.699e-02	0.313	-3.572	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AA886888	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
201223_s_at	-0.335	9.235	-2.447	2.700e-02	0.313	-3.572	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	NM_002874	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
204369_at	-0.587	5.570	-2.447	2.700e-02	0.313	-3.572	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	3	180349004	NM_006218	5290	3q26.3	Hs.553498 Hs.85701	259	nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex glucose metabolic process protein amino acid phosphorylation anti-apoptosis signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor lamellipodium regulation of multicellular organism growth protein kinase B signaling cascade insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
205570_at	0.361	4.189	2.447	2.701e-02	0.313	-3.573	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	10	-22863771	NM_005028	5305	10p12.2	Hs.57079	24	nucleotide binding ATP binding cellular_component kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity phosphorylation transferase activity phosphatidylinositol metabolic process	Inositol phosphate metabolism Phosphatidylinositol signaling system Regulation of actin cytoskeleton
212882_at	-0.316	5.474	-2.447	2.703e-02	0.313	-3.573	KLHL18	kelch-like 18 (Drosophila)	3	47299333	AB018338	23276	3p21.31	Hs.517946	8	protein binding
202220_at	-0.380	7.512	-2.446	2.704e-02	0.313	-3.574	KIAA0907	KIAA0907	1	-154149459	NM_014949	22889	1q22	Hs.719258	6
215328_at	0.289	4.658	2.446	2.704e-02	0.313	-3.574	EFR3B	EFR3 homolog B (S. cerevisiae)	2	25118476	AB023170	22979	2p23.3	Hs.4892	6	binding
223266_at	-0.490	8.997	-2.446	2.706e-02	0.313	-3.575	STRADB	STE20-related kinase adaptor beta	2	202024636	AB038950	55437	2q33.1	Hs.652338	12	nucleotide binding protein kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation protein export from nucleus cell cycle activation of protein kinase activity
236166_at	-0.474	7.559	-2.446	2.707e-02	0.313	-3.575	LOC285147	hypothetical protein LOC285147	2		AW195071	285147	2p25.2	Hs.467627	1
207261_at	0.272	2.293	2.446	2.707e-02	0.313	-3.575	CNGA3	cyclic nucleotide gated channel alpha 3	2	98329049	NM_001298	1261	2q11.2	Hs.234785	26	nucleotide binding ion transport signal transduction visual perception ligand-gated ion channel activity membrane integral to membrane cGMP binding response to stimulus	Olfactory transduction
207573_x_at	0.294	11.545	2.446	2.708e-02	0.313	-3.575	ATP5L	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G	11	117777313	NM_006476	10632	11q23.3	Hs.486360	15	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) protein binding mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
232510_s_at	-0.334	6.473	-2.446	2.708e-02	0.313	-3.575	DPP3	dipeptidyl-peptidase 3	11	66004455	AW250952	10072	11q12-q13.1	Hs.502914	29	aminopeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity dipeptidyl-peptidase activity zinc ion binding metal ion binding
206105_at	0.325	4.488	2.446	2.708e-02	0.313	-3.575	AFF2	AF4/FMR2 family, member 2	X	147389830	NM_002025	2334	Xq28	Hs.496911	21	protein binding brain development
1569699_at	0.428	4.139	2.445	2.710e-02	0.313	-3.576	AK7	adenylate kinase 7	14	95928200	BC023986	122481	14q32.2	Hs.667462	4	nucleotide binding adenylate kinase activity ATP binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process metabolic process transferase activity nucleobase, nucleoside, nucleotide kinase activity	Purine metabolism Metabolic pathways
226529_at	-0.485	9.306	-2.445	2.710e-02	0.313	-3.576	TMEM106B	transmembrane protein 106B	7	12217372	BF513060	54664	7p21.3	Hs.396358	10	molecular_function cellular_component biological_process membrane integral to membrane
225208_s_at	-0.293	7.809	-2.445	2.710e-02	0.313	-3.576	FAM103A1	family with sequence similarity 103, member A1	15	81445998	AW575350	83640	15q25.2	Hs.80624	3
201543_s_at	0.319	7.255	2.445	2.711e-02	0.313	-3.576	SAR1A	SAR1 homolog A (S. cerevisiae)	10	-71579973	NM_020150	56681	10q22.1	Hs.499960 Hs.594910	13	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport vesicle-mediated transport sarcoplasmic reticulum
208405_s_at	-0.403	8.931	-2.445	2.712e-02	0.313	-3.576	CD164	CD164 molecule, sialomucin	6	-109794411	NM_006016	8763	6q21	Hs.520313 Hs.644693	17	extracellular region plasma membrane integral to plasma membrane immune response cell adhesion heterophilic cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation	Lysosome
242070_at	0.269	3.143	2.445	2.714e-02	0.313	-3.577	LOC728485	hypothetical protein LOC728485	19		AI014470	728485	19q13.12	Hs.157101	2
209698_at	0.345	6.656	2.444	2.714e-02	0.313	-3.577	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AF216493	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
219015_s_at	-0.429	4.438	-2.444	2.716e-02	0.313	-3.578	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_018466	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
213773_x_at	-0.359	7.746	-2.444	2.716e-02	0.313	-3.578	NSUN5	NOL1/NOP2/Sun domain family, member 5	7	-72355161	AW248552	55695	7q11.23	Hs.647060	9	methyltransferase activity transferase activity
202695_s_at	-0.530	3.819	-2.444	2.718e-02	0.313	-3.578	STK17A	serine/threonine kinase 17a	7	43589216	NM_004760	9263	7p12-p14	Hs.709489	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity
201792_at	0.244	5.774	2.444	2.719e-02	0.313	-3.578	AEBP1	AE binding protein 1	7	44110484	NM_001129	165	7p13	Hs.439463	9	skeletal system development transcription factor activity metallocarboxypeptidase activity extracellular region nucleus cytoplasm proteolysis cell adhesion muscle organ development zinc ion binding regulation of transcription
218152_at	-0.319	7.478	-2.443	2.721e-02	0.313	-3.579	HMG20A	high-mobility group 20A	15	75500297	NM_018200	10363	15q24	Hs.69594	9	transcription factor activity protein binding nucleus nucleolus regulation of transcription, DNA-dependent chromatin modification
211352_s_at	-0.642	5.796	-2.443	2.722e-02	0.313	-3.579	NCOA3	nuclear receptor coactivator 3	20	45564063	U80737	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
208847_s_at	-0.260	8.846	-2.443	2.723e-02	0.313	-3.580	ADH5	alcohol dehydrogenase 5 (class III), chi polypeptide	4	-100211152	M29872	128	4q21-q25	Hs.78989	33	retinoid metabolic process respiratory system process alcohol dehydrogenase (NAD) activity binding fatty acid binding cytoplasm mitochondrion ethanol oxidation zinc ion binding electron carrier activity oxidoreductase activity peptidyl-cysteine S-nitrosylation formaldehyde dehydrogenase activity response to lipopolysaccharide protein homodimerization activity positive regulation of blood pressure formaldehyde catabolic process metal ion binding response to nitrosative stress response to redox state S-(hydroxymethyl)glutathione dehydrogenase activity oxidation reduction	Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Methane metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
205240_at	-0.433	5.059	-2.443	2.723e-02	0.313	-3.580	GPSM2	G-protein signaling modulator 2 (AGS3-like, C. elegans)	1	109221125	NM_013296	29899	1p13.3	Hs.584901	11	GTPase activator activity nucleus nucleolus cytoplasm Golgi apparatus cell cortex signal transduction G-protein coupled receptor protein signaling pathway identical protein binding
51226_at	0.279	3.438	2.443	2.723e-02	0.313	-3.580	RBM12B	RNA binding motif protein 12B	8	-94812903	N53536	389677	8q22.1	Hs.192788	3	nucleotide binding RNA binding
219594_at	-1.028	6.774	-2.443	2.724e-02	0.313	-3.580	NINJ2	ninjurin 2	12	-543722	NM_016533	4815	12p13	Hs.656450	5	protein binding integral to plasma membrane cell adhesion neuron adhesion nervous system development membrane tissue regeneration
1570128_at	0.291	3.540	2.443	2.724e-02	0.313	-3.580	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A	16	68938324	BC025771	55308	16q22.1	Hs.656037	5	nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport
1555902_at	0.446	4.454	2.442	2.726e-02	0.313	-3.581	ARMCX5	armadillo repeat containing, X-linked 5	X	101740813	BC022066	64860	Xq22.1-q22.3	Hs.522729	5	binding
202347_s_at	-0.325	7.548	-2.442	2.728e-02	0.313	-3.581	UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	4	39376058	AB022435	3093	4p14	Hs.50308 Hs.714332	20	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding cytoplasm ubiquitin-dependent protein catabolic process ligase activity ubiquitin protein ligase binding post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
226474_at	0.415	5.782	2.442	2.728e-02	0.313	-3.582	NLRC5	NLR family, CARD domain containing 5	16	55580910	AA005023	84166	16q13	Hs.528836	3	nucleotide binding protein binding ATP binding cytoplasm
207213_s_at	-0.647	7.347	-2.442	2.729e-02	0.313	-3.582	USP2	ubiquitin specific peptidase 2	11	-118731134, -118731134	NM_004205	9099	11q23.3	Hs.524085	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm plasma membrane ubiquitin-dependent protein catabolic process peptidase activity
219706_at	-0.391	6.858	-2.441	2.732e-02	0.314	-3.583	C20orf29	chromosome 20 open reading frame 29	20	3749202	NM_018347	55317	20p13	Hs.104806	4
1564713_a_at	0.254	5.384	2.441	2.735e-02	0.314	-3.584	FOXN4	forkhead box N4	12	-108200165	AF425597	121643	12q24.11	Hs.528316	6	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
232965_at	-0.214	4.048	-2.440	2.738e-02	0.314	-3.585	LOC400684	hypothetical gene supported by BC000922	19		BC000922	400684	19q13.11	Hs.438766	1
219854_at	0.448	5.260	2.440	2.739e-02	0.314	-3.585	ZNF14	zinc finger protein 14	19	-19682280	NM_021030	7561	19p13.3-p13.2	Hs.659932	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
219027_s_at	-0.333	7.450	-2.440	2.739e-02	0.314	-3.585	MYO9A	myosin IXA	15	-69905414	NM_006901	4649	15q22-q23	Hs.546268	8	nucleotide binding motor activity actin binding GTPase activator activity protein binding ATP binding intracellular intracellular signaling cascade visual perception zinc ion binding membrane integral to membrane myosin complex diacylglycerol binding metal ion binding
232907_at	0.288	6.143	2.439	2.741e-02	0.314	-3.586	UBR4	ubiquitin protein ligase E3 component n-recognin 4	1	-19273586	AU145867	23352	1p36.13	Hs.148078 Hs.649405	11	ubiquitin-protein ligase activity calmodulin binding nucleus cytoplasm cytoskeleton zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process interspecies interaction between organisms metal ion binding
226775_at	-0.549	6.845	-2.439	2.742e-02	0.314	-3.586	ENY2	enhancer of yellow 2 homolog (Drosophila)	8	110415811	N30904	56943	8q23.1	Hs.492555	5	SAGA complex nucleus transport chromatin modification histone deubiquitination ligand-dependent nuclear receptor transcription coactivator activity regulation of transcription positive regulation of transcription, DNA-dependent mRNA transport
212515_s_at	-0.712	8.010	-2.439	2.742e-02	0.314	-3.586	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	X	41077594	BG492602	1654	Xp11.3-p11.23	Hs.719127	34	nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus cytoplasm plasma membrane nuclear speck hydrolase activity interspecies interaction between organisms	RIG-I-like receptor signaling pathway
231223_at	0.530	3.489	2.439	2.743e-02	0.314	-3.586	CSMD1	CUB and Sushi multiple domains 1	8	-2780281	R41565	64478	8p23.2	Hs.571466	22	membrane integral to membrane
201533_at	-0.343	9.202	-2.439	2.744e-02	0.314	-3.587	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	3	41215945	NM_001904	1499	3p21	Hs.476018	680	negative regulation of transcription from RNA polymerase II promoter skeletal system development patterning of blood vessels gastrulation with mouth forming second endoderm formation cell fate specification endodermal cell fate commitment epithelial to mesenchymal transition chromatin binding double-stranded DNA binding transcription factor activity transcription coactivator activity signal transducer activity membrane fraction nucleus transcription factor complex cytoplasm centrosome cytosol cytoskeleton plasma membrane fascia adherens apoptosis cell-matrix adhesion synaptic transmission ectoderm development glial cell fate determination heart development protein C-terminus binding transcription factor binding anterior/posterior axis specification dorsal/ventral axis specification proximal/distal pattern formation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process basolateral plasma membrane lateral plasma membrane morphogenesis of embryonic epithelium cell-cell adhesion catenin complex kinase binding protein phosphatase binding Z disc lamellipodium hemopoiesis lung development androgen receptor signaling pathway positive regulation of epithelial cell differentiation beta-catenin destruction complex forebrain development regulation of centriole-centriole cohesion pancreas development microvillus membrane negative regulation of chondrocyte differentiation T cell differentiation in the thymus cellular protein localization Axin-APC-beta-catenin-GSK3B complex embryonic hindlimb morphogenesis embryonic arm morphogenesis regulation of cell proliferation odontogenesis of dentine-containing tooth embryonic digit morphogenesis apical junction complex positive regulation of MAPKKK cascade apical part of cell alpha-catenin binding cadherin binding bone resorption positive regulation of osteoblast differentiation negative regulation of osteoclast differentiation cell maturation synaptic vesicle transport thymus development camera-type eye morphogenesis androgen receptor binding synapse organization Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex I-SMAD binding	Wnt signaling pathway Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Melanogenesis Pathogenic Escherichia coli infection - EHEC Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1553067_a_at	0.279	3.717	2.439	2.744e-02	0.314	-3.587	GNRHR2	gonadotropin-releasing hormone (type 2) receptor 2	1	-144221176	NM_057163	114814	1q12	Hs.711567 Hs.714903	12	receptor activity G-protein coupled receptor activity gonadotropin-releasing hormone receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
204831_at	-0.496	6.772	-2.438	2.747e-02	0.314	-3.588	CDK8	cyclin-dependent kinase 8	13	25726755	R59697	1024	13q12	Hs.382306	38	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation RNA polymerase II carboxy-terminal domain kinase activity transferase activity regulation of transcription
210228_at	0.239	5.771	2.438	2.751e-02	0.315	-3.589	CSF2	colony stimulating factor 2 (granulocyte-macrophage)	5	131437383	M11734	1437	5q31.1	Hs.1349	172	cytokine activity granulocyte macrophage colony-stimulating factor receptor binding protein binding extracellular region extracellular space immune response positive regulation of cell proliferation positive regulation of foam cell differentiation positive regulation of tyrosine phosphorylation of Stat5 protein myeloid dendritic cell differentiation negative regulation of apoptosis positive regulation of DNA replication positive regulation of survival gene product expression negative regulation of cytolysis	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway
230049_at	0.224	4.975	2.437	2.752e-02	0.315	-3.589	TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	11	62295450	AW303570	10629	11q12.3	Hs.714400	13	histone deacetylase complex DNA binding RNA polymerase II transcription factor activity transcription coactivator activity histone acetyltransferase activity protein binding nucleus chromatin remodeling transcription initiation regulation of transcription from RNA polymerase II promoter transcription initiation factor activity STAGA complex histone H3 acetylation regulation of transcription factor activity	Basal transcription factors
240967_at	-0.544	4.341	-2.437	2.752e-02	0.315	-3.589	KRTAP19-3	keratin associated protein 19-3	21	-30785652	AI288919	337970	21q22.1	Hs.60480	1	intermediate filament
219704_at	0.443	7.672	2.437	2.754e-02	0.315	-3.590	YBX2	Y box binding protein 2	17	-7132294	NM_015982	51087	17p11.2-p13.1	Hs.567494	10	DNA binding RNA binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter spermatogenesis translational attenuation
207700_s_at	-0.766	7.525	-2.437	2.755e-02	0.315	-3.590	NCOA3	nuclear receptor coactivator 3	20	45564063	NM_006534	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
216760_at	0.407	4.730	2.437	2.755e-02	0.315	-3.590	HRASLS2	HRAS-like suppressor 2	11	-63076817	AK025029	54979	11q12.3	Hs.272805	2
203916_at	0.228	6.513	2.437	2.755e-02	0.315	-3.590	NDST2	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2	10	-75231674	NM_003635	8509	10q22	Hs.654758	9	Golgi apparatus sulfotransferase activity cellular process heparan sulfate proteoglycan biosynthetic process [heparan sulfate]-glucosamine N-sulfotransferase activity membrane integral to membrane transferase activity hydrolase activity	Heparan sulfate biosynthesis Metabolic pathways
201779_s_at	-0.441	9.059	-2.437	2.757e-02	0.315	-3.591	RNF13	ring finger protein 13	3	151013164	AF070558	11342	3q25.1	Hs.12333 Hs.712766	10	protein binding nucleus cytoplasm zinc ion binding metal ion binding
220492_s_at	0.251	3.639	2.436	2.760e-02	0.315	-3.592	OTOF	otoferlin	2	-26533575, -26533575	NM_004802	9381	2p23.1	Hs.91608	17	molecular_function calcium ion binding membrane fraction endoplasmic reticulum cytosol plasma membrane membrane fusion sensory perception of sound integral to membrane cell junction cytoplasmic vesicle synapse
200732_s_at	-0.544	10.872	-2.436	2.761e-02	0.315	-3.592	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	AL578310	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
218507_at	0.326	5.653	2.435	2.763e-02	0.315	-3.593	C7orf68	chromosome 7 open reading frame 68	7	127883119	NM_013332	29923	7q32.1	Hs.710088	9	molecular_function cellular_component response to stress membrane integral to membrane
221240_s_at	0.292	6.534	2.435	2.764e-02	0.315	-3.593	B3GNT4	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4	12	121254180	NM_030765	79369	12q24	Hs.363315	5	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
201158_at	-0.328	5.670	-2.435	2.765e-02	0.315	-3.593	NMT1	N-myristoyltransferase 1	17	40494205	AI570834	4836	17q21.31	Hs.532790	58	in utero embryonic development glycylpeptide N-tetradecanoyltransferase activity cellular_component cytoplasm cytosol N-terminal protein myristoylation protein lipoylation transferase activity
214681_at	0.213	4.794	2.435	2.766e-02	0.315	-3.594	GK	glycerol kinase	X	30581396	AI830490	2710	Xp21.3	Hs.1466	20	nucleotide binding glycerol kinase activity glycerol kinase activity ATP binding cytoplasm mitochondrion mitochondrial outer membrane cytosol carbohydrate metabolic process glycerol-3-phosphate metabolic process membrane transferase activity	Glycerolipid metabolism Metabolic pathways PPAR signaling pathway
226656_at	-0.390	8.006	-2.434	2.770e-02	0.316	-3.595	CRTAP	cartilage associated protein	3	33130453	AW024741	10491	3p22.3	Hs.719160	10	extracellular region proteinaceous extracellular matrix
216181_at	0.279	6.489	2.434	2.772e-02	0.316	-3.596	SYNJ2	synaptojanin 2	6	158322906	AK026758	8871	6q25.3	Hs.434494	18	RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity protein binding membrane dephosphorylation hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
238616_at	0.305	4.654	2.434	2.772e-02	0.316	-3.596	QDPR	quinoid dihydropteridine reductase	4	-17097117	AA844132	5860	4p15.31	Hs.75438	37	6,7-dihydropteridine reductase activity binding cytoplasm cellular amino acid metabolic process tetrahydrobiopterin biosynthetic process electron carrier activity oxidoreductase activity dihydrobiopterin metabolic process oxidation reduction	Folate biosynthesis Metabolic pathways
211072_x_at	-0.549	10.538	-2.434	2.773e-02	0.316	-3.596	TUBA1B	tubulin, alpha 1b	12	-47807832	BC006481	10376	12q13.12	Hs.524390 Hs.719075	42	nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
205163_at	-0.703	13.398	-2.433	2.774e-02	0.316	-3.596	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	16	30293623	NM_013292	29895	16p11.2	Hs.50889	5	motor activity calcium ion binding muscle myosin complex skeletal muscle tissue development structural constituent of muscle myosin complex	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
201444_s_at	-0.654	6.748	-2.433	2.778e-02	0.316	-3.598	ATP6AP2	ATPase, H+ transporting, lysosomal accessory protein 2	X	40325159	NM_005765	10159	Xp11.4	Hs.495960	17	angiotensin maturation receptor activity protein binding external side of plasma membrane membrane integral to membrane positive regulation of transforming growth factor-beta1 production regulation of MAPKKK cascade
200037_s_at	-0.336	9.593	-2.432	2.783e-02	0.317	-3.599	CBX3	chromobox homolog 3 (HP1 gamma homolog, Drosophila)	7	26207623, 26207848	NM_016587	11335	7p15.2	Hs.381189 Hs.706294	45	condensed chromosome, centromeric region chromatin chromatin binding nucleus nuclear inner membrane polytene chromosome chromocenter nuclear euchromatin spindle chromatin assembly or disassembly chromatin remodeling negative regulation of transcription general transcriptional repressor activity enzyme binding protein domain specific binding nuclear centromeric heterochromatin
209030_s_at	0.584	6.414	2.432	2.784e-02	0.317	-3.600	CADM1	cell adhesion molecule 1	11	-114549554	NM_014333	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
209005_at	0.297	7.759	2.431	2.785e-02	0.317	-3.600	FBXL5	F-box and leucine-rich repeat protein 5	4	-15215251	AF157323	26234	4p15.32	Hs.643433	13	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process
218235_s_at	-0.494	10.276	-2.431	2.789e-02	0.317	-3.601	UTP11L	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)	1	38250970	NM_016037	51118	1p34.3	Hs.472038 Hs.637686	11	protein binding extracellular space nucleus nucleolus cytoplasm rRNA processing induction of apoptosis nervous system development small-subunit processome nerve growth factor receptor signaling pathway
209394_at	-0.467	5.788	-2.431	2.790e-02	0.317	-3.601	ASMTL	acetylserotonin O-methyltransferase-like	X, Y	-1482031, -1482031	BC002508	8623	Xp22.3 Yp11.3	Hs.533514	10	cellular_component cytoplasm acetylserotonin O-methyltransferase activity melatonin biosynthetic process
207408_at	0.296	6.398	2.430	2.794e-02	0.317	-3.603	SLC22A14	solute carrier family 22, member 14	3	38322448	NM_004803	9389	3p21.3	Hs.165559	5	integral to plasma membrane organic cation transmembrane transporter activity organic cation transport membrane
239173_at	-0.408	5.119	-2.430	2.795e-02	0.317	-3.603	INADL	InaD-like (Drosophila)	1	61980736	AI697184	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
235551_at	-0.268	3.803	-2.429	2.796e-02	0.318	-3.603	WDR4	WD repeat domain 4	21	-43142404, -43136272	AA555280	10785	21q22.3	Hs.248815	10	protein binding nucleus nucleoplasm cytoplasm tRNA modification tRNA (guanine-N7-)-methyltransferase activity
222624_s_at	-0.543	5.890	-2.429	2.797e-02	0.318	-3.604	ZNF639	zinc finger protein 639	3	180524244	AA224199	51193	3q26.33	Hs.632578	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
219986_s_at	0.267	6.479	2.429	2.801e-02	0.318	-3.605	ACAD10	acyl-Coenzyme A dehydrogenase family, member 10	12	110608239, 110608239	NM_025247	80724	12q24.12	Hs.331141	6	acyl-CoA dehydrogenase activity metabolic process electron carrier activity hydrolase activity FAD binding
241899_at	0.302	5.396	2.428	2.801e-02	0.318	-3.605	LOC553103	hypothetical LOC553103			AA524418	553103		Hs.633421	1
221029_s_at	0.256	4.037	2.428	2.802e-02	0.318	-3.605	WNT5B	wingless-type MMTV integration site family, member 5B	12	1596482, 1608672	NM_030775	81029	12p13.3	Hs.306051	11	signal transducer activity extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
232536_at	0.233	5.762	2.428	2.805e-02	0.318	-3.606	C21orf30	chromosome 21 open reading frame 30	21		AL117578	54083	21q22.3	Hs.542533	2	nucleus
214295_at	0.315	4.094	2.428	2.806e-02	0.318	-3.607	KIAA0485	hypothetical LOC57235			AW129056	57235		Hs.604754	1
201465_s_at	-0.665	6.572	-2.427	2.810e-02	0.318	-3.608	JUN	jun oncogene	1	-59019050	BC002646	3725	1p32-p31	Hs.714791	443	nuclear chromosome transcription factor activity RNA polymerase II transcription factor activity Rho GTPase activator activity nucleus transcription factor complex cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation transcription factor binding negative regulation of cell proliferation cellular process promoter binding negative regulation of protein amino acid autophosphorylation leading edge cell differentiation response to drug positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein dimerization activity regulation of cell cycle SMAD protein signal transduction R-SMAD binding	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma
209721_s_at	-0.412	7.258	-2.427	2.810e-02	0.318	-3.608	IFFO1	intermediate filament family orphan 1	12	-6518954, -6518954	BC002857	25900	12p13.3	Hs.15243	7	intermediate filament
221166_at	0.258	4.274	2.427	2.811e-02	0.319	-3.608	FGF23	fibroblast growth factor 23	12	-4347653	NM_020638	8074	12p13.3	Hs.287370	83	extracellular region extracellular region extracellular space growth factor activity fibroblast growth factor receptor signaling pathway cell differentiation regulation of bone mineralization cellular phosphate ion homeostasis	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
236666_s_at	0.307	6.521	2.426	2.812e-02	0.319	-3.608	LOC390205	leucine rich repeat containing 10-like	11	61032847	AA923289	390205	11q12.2	Hs.441122	1	protein binding
229407_at	0.327	3.411	2.426	2.812e-02	0.319	-3.609	SDK1	sidekick homolog 1, cell adhesion molecule (chicken)	7	3307605, 4135842	AF131799	221935	7p22.2	Hs.653013	7	protein binding cell adhesion membrane integral to membrane
223589_at	0.313	5.059	2.426	2.813e-02	0.319	-3.609	ZNF416	zinc finger protein 416	19	-62774745	BC000130	55659	19q13.4	Hs.247711	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224800_at	-0.401	7.481	-2.426	2.815e-02	0.319	-3.609	WDFY1	WD repeat and FYVE domain containing 1	2	-224448308	AK022888	57590	2q36.1	Hs.708107	5	phosphatidylinositol binding nucleus early endosome cytosol biological_process zinc ion binding metal ion binding
214336_s_at	0.277	4.822	2.426	2.816e-02	0.319	-3.610	COPA	coatomer protein complex, subunit alpha	1	-158525000	AI621079	1314	1q23-q25	Hs.162121 Hs.685025	30	hormone activity structural molecule activity calcium ion binding extracellular region extracellular space soluble fraction cytoplasm endoplasmic reticulum microsome Golgi apparatus cytosol protein folding intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat pancreatic juice secretion cytoplasmic vesicle COPI coating of Golgi vesicle unfolded protein binding
41856_at	0.243	7.104	2.426	2.817e-02	0.319	-3.610	UNC5B	unc-5 homolog B (C. elegans)	10	72642303	AL049370	219699	10q22.1	Hs.522997	12	receptor activity protein binding apoptosis signal transduction multicellular organismal development membrane integral to membrane	Axon guidance
227428_at	-0.374	6.929	-2.425	2.818e-02	0.319	-3.610	GABPA	GA binding protein transcription factor, alpha subunit 60kDa	21	26029199	BE876628	2551	21q21-q22.1 21q21.3	Hs.246310 Hs.473470	34	negative regulation of transcription from RNA polymerase II promoter in utero embryonic development transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nucleolus sequence-specific DNA binding
216266_s_at	-0.546	5.467	-2.425	2.822e-02	0.319	-3.612	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	8	-68272450	AK025637	10565	8q13	Hs.656902	22	ARF guanyl-nucleotide exchange factor activity binding intracellular exocytosis ARF GTPase activator activity myosin binding regulation of ARF protein signal transduction
202708_s_at	-0.619	8.067	-2.424	2.825e-02	0.319	-3.612	HIST2H2BE	histone cluster 2, H2be	1	-148122633	NM_003528	8349	1q21-q23	Hs.2178	50	nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly defense response to bacterium	Systemic lupus erythematosus
203675_at	-0.451	6.775	-2.424	2.825e-02	0.319	-3.613	NUCB2	nucleobindin 2	11	17254861	NM_005013	4925	11p15.1-p14	Hs.654599	15	DNA binding calcium ion binding extracellular region extracellular space nucleus nuclear outer membrane cytoplasm endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus cytosol plasma membrane
211090_s_at	-1.025	5.105	-2.423	2.829e-02	0.319	-3.614	PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	6	3966567	Z25435	8899	6p25.2	Hs.159014	20	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus spliceosomal complex chromosome mRNA processing protein amino acid phosphorylation RNA splicing transferase activity
1561434_at	0.315	3.507	2.423	2.830e-02	0.319	-3.614	C15orf45	chromosome 15 open reading frame 45	15		AI956139	641318	15q13.3	Hs.711585	2
201230_s_at	-0.462	7.925	-2.423	2.830e-02	0.319	-3.614	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	NM_006321	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
1564307_a_at	0.339	2.847	2.423	2.831e-02	0.319	-3.614	A2ML1	alpha-2-macroglobulin-like 1	12	8866416	AL832750	144568	12p13.31	Hs.620532	8	serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space regulation of endopeptidase activity
204378_at	0.300	5.673	2.423	2.834e-02	0.320	-3.615	BCAS1	breast carcinoma amplified sequence 1	20	-51993485	NM_003657	8537	20q13.2	Hs.400556	12	protein binding cytoplasm
232160_s_at	-0.384	6.866	-2.422	2.834e-02	0.320	-3.615	TNIP2	TNFAIP3 interacting protein 2	4	-2713184, -2713184	AL137262	79155	4p16.3	Hs.719161	20	protein binding cytoplasm I-kappaB kinase/NF-kappaB cascade
238441_at	-0.613	9.214	-2.422	2.837e-02	0.320	-3.616	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	AI928203	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
220083_x_at	-0.462	4.969	-2.422	2.837e-02	0.320	-3.616	UCHL5	ubiquitin carboxyl-terminal hydrolase L5	1	-191251521	NM_016017	51377	1q32	Hs.591458	15	ubiquitin thiolesterase activity protein binding intracellular cytosol ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity protein complex
1553593_a_at	-0.649	6.101	-2.422	2.838e-02	0.320	-3.616	TAL2	T-cell acute lymphocytic leukemia 2	9	107464558	NM_005421	6887	9q32	Hs.247978	9	DNA binding protein binding nucleus behavior post-embryonic development thalamus development transcription regulator activity midbrain development multicellular organism growth regulation of transcription
217799_x_at	-0.345	7.183	-2.421	2.840e-02	0.320	-3.617	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	7	-129260230	NM_003344	7328	7q32	Hs.643548	16	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity regulation of protein metabolic process	Ubiquitin mediated proteolysis
217434_at	0.257	2.870	2.421	2.840e-02	0.320	-3.617	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)	18	-13872042	Y10259	4158	18p11.2	Hs.248144	50	receptor activity G-protein coupled receptor activity adrenocorticotropin receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger	Neuroactive ligand-receptor interaction
206142_at	0.420	2.842	2.421	2.840e-02	0.320	-3.617	ZNF135	zinc finger protein 135	19	63262423	NM_003436	7694	19q13.4	Hs.85863	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221268_s_at	-0.703	3.594	-2.421	2.841e-02	0.320	-3.618	SGPP1	sphingosine-1-phosphate phosphatase 1	14	-63220687	NM_030791	81537	14q23.2	Hs.24678	11	membrane fraction endoplasmic reticulum sphingolipid metabolic process sphinganine-1-phosphate metabolic process sphingosine metabolic process apoptosis membrane integral to membrane hydrolase activity sphingosine-1-phosphate phosphatase activity	Sphingolipid metabolism
201148_s_at	0.305	7.204	2.421	2.842e-02	0.320	-3.618	TIMP3	TIMP metallopeptidase inhibitor 3	22	31526801	AW338933	7078	22q12.1-q13.2 22q12.3	Hs.644633 Hs.714168	117	enzyme inhibitor activity protein binding extracellular region basement membrane visual perception metalloendopeptidase inhibitor activity response to organic cyclic substance tissue regeneration response to estrogen stimulus response to stimulus negative regulation of membrane protein ectodomain proteolysis
237755_s_at	0.231	3.810	2.421	2.842e-02	0.320	-3.618	WDR16	WD repeat domain 16	17	9420668	AW673231	146845	17p13.1	Hs.232270	5	protein binding cytoplasm
218409_s_at	-0.288	6.685	-2.421	2.844e-02	0.320	-3.618	DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	10	-22085482	NM_022365	64215	10p12.31	Hs.499000	8	ATPase activator activity DNA binding nucleus endoplasmic reticulum microsome regulation of translation protein folding membrane integral to membrane heat shock protein binding negative regulation of proteolysis regulation of protein secretion unfolded protein binding chaperone binding
211191_at	0.235	4.078	2.421	2.844e-02	0.320	-3.619	CD84	CD84 molecule	1	-158782410	AF054818	8832	1q24	Hs.398093	23	receptor activity protein binding plasma membrane integral to plasma membrane defense response cell adhesion homophilic cell adhesion
220253_s_at	-0.803	5.164	-2.420	2.846e-02	0.320	-3.619	LRP12	low density lipoprotein-related protein 12	8	-105570642	NM_013437	29967	8q22.2-q23.1	Hs.600630	8	receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth
214669_x_at	0.429	5.412	2.420	2.846e-02	0.320	-3.619	IGKC	immunoglobulin kappa constant	2		BG485135	3514	2p12	Hs.449621 Hs.703932	31	antigen binding protein binding extracellular region extracellular region immune response
231126_at	0.205	4.946	2.420	2.847e-02	0.320	-3.619	C2orf70	chromosome 2 open reading frame 70	2	26638984	AA778539	339778	2p23.3	Hs.407083	1
202447_at	0.480	10.373	2.420	2.848e-02	0.320	-3.620	DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	8	91082755	NM_001359	1666	8q21.3	Hs.492212	22	binding mitochondrion fatty acid beta-oxidation fatty acid beta-oxidation 2,4-dienoyl-CoA reductase (NADPH) activity 2,4-dienoyl-CoA reductase (NADPH) activity oxidoreductase activity protein homotetramerization oxidation reduction NADPH binding
229743_at	-0.277	6.571	-2.420	2.850e-02	0.320	-3.620	ZNF438	zinc finger protein 438	10	-31173572, -31173572	AI886666	220929	10p11.23-p11.22	Hs.660642	6	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212390_at	-0.357	12.038	-2.419	2.851e-02	0.320	-3.621	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	AB007923	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
205986_at	0.303	5.830	2.419	2.852e-02	0.320	-3.621	AATK	apoptosis-associated tyrosine kinase	17	-76705690	NM_004920	9625	17q25.3	Hs.514575	15	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm mitochondrion protein amino acid phosphorylation membrane integral to membrane transferase activity perinuclear region of cytoplasm
216503_s_at	0.490	4.920	2.419	2.853e-02	0.320	-3.621	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10	21863107, 21863579	AF060927	8028	10p12	Hs.30385	19	transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding
1554290_at	-0.401	3.054	-2.419	2.853e-02	0.320	-3.621	HERC3	hect domain and RLD 3	4	89732669	BC038960	8916	4q21	Hs.35804	7	intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cytoplasmic vesicle	Ubiquitin mediated proteolysis
210183_x_at	-0.397	10.622	-2.419	2.854e-02	0.320	-3.622	PNN	pinin, desmosome associated protein	14	38714137	AF112222	5411	14q21.1	Hs.409965	30	DNA binding structural molecule activity protein binding nucleus spliceosomal complex nucleolus cytoplasm intermediate filament plasma membrane mRNA processing cell adhesion RNA splicing nuclear speck desmosome regulation of transcription
203694_s_at	-0.320	7.166	-2.419	2.855e-02	0.320	-3.622	DHX16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	6	-30728885, -2069456, -1867754	NM_003587	8449	6p21.3	Hs.485060	9	nucleotide binding nucleic acid binding RNA helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity
202125_s_at	-0.456	7.220	-2.419	2.855e-02	0.320	-3.622	TRAK2	trafficking protein, kinesin binding 2	2	-201950174	NM_015049	66008	2q33	Hs.152774	16	cytoplasm plasma membrane GABA receptor binding
222862_s_at	0.263	4.387	2.419	2.856e-02	0.320	-3.622	AK5	adenylate kinase 5	1	77520329, 77520874	BG169832	26289	1p31	Hs.559718	5	nucleotide binding adenylate kinase activity ATP binding cytoplasm cytosol cytosol nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ADP biosynthetic process dADP biosynthetic process pyrimidine ribonucleotide biosynthetic process transferase activity nucleoside kinase activity ATP metabolic process	Purine metabolism Metabolic pathways
1554627_a_at	-0.504	6.823	-2.419	2.856e-02	0.320	-3.622	ASCC1	activating signal cointegrator 1 complex subunit 1	10	-73526283	BC012291	51008	10pter-q25.3	Hs.500007	7	RNA binding cytoplasm regulation of transcription
236909_at	0.309	3.093	2.418	2.857e-02	0.320	-3.623	C2orf77	chromosome 2 open reading frame 77	2	-170210180	AW339899	129881	2q31.1	Hs.370111	2
202041_s_at	0.366	8.116	2.418	2.862e-02	0.321	-3.624	FIBP	fibroblast growth factor (acidic) intracellular binding protein	11	-65407786	NM_004214	9158	11q13.1	Hs.7768	10	protein binding membrane fraction nucleus mitochondrion fibroblast growth factor receptor signaling pathway membrane fibroblast growth factor binding
210290_at	-0.294	4.178	-2.417	2.864e-02	0.321	-3.625	ZNF174	zinc finger protein 174	16	3391190, 3391190	BC001161	7727	16p13.3	Hs.155204	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding intracellular nucleus nucleolus cytoplasm cytoskeleton regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204697_s_at	0.210	3.708	2.417	2.865e-02	0.321	-3.625	CHGA	chromogranin A (parathyroid secretory protein 1)	14	92459197	NM_001275	1113	14q32	Hs.150793	96	calcium ion binding extracellular region regulation of blood pressure
207939_x_at	-0.292	7.544	-2.417	2.865e-02	0.321	-3.625	RNPS1	RNA binding protein S1, serine-rich domain	16	-2243122, -2243122	NM_006711	10921	16p13.3	Hs.355643	30	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus cytoplasm transcription RNA splicing nuclear speck
222683_at	-0.431	7.976	-2.417	2.868e-02	0.321	-3.626	RNF20	ring finger protein 20	9	103335953	AK022532	56254	9q22	Hs.656088	19	ubiquitin ligase complex protein polyubiquitination p53 binding transcription coactivator activity ubiquitin-protein ligase activity nucleus chromosome nucleolus ubiquitin-dependent protein catabolic process zinc ion binding histone monoubiquitination chromatin modification ligase activity negative regulation of cell migration ubiquitin protein ligase binding regulation of gene-specific transcription histone H2B ubiquitination histone H3-K79 methylation histone binding positive regulation of transcription metal ion binding histone H3-K4 methylation
201489_at	0.495	9.307	2.416	2.868e-02	0.321	-3.626	PPIF	peptidylprolyl isomerase F	10	80777225	BC005020	10105	10q22-q23	Hs.381072	13	peptidyl-prolyl cis-trans isomerase activity membrane fraction mitochondrion mitochondrial matrix protein folding isomerase activity peptide binding
233535_at	0.296	4.652	2.416	2.869e-02	0.321	-3.626	ATP13A4	ATPase type 13A4	3	-194602559	AL512736	84239	3q29	Hs.674423	4	nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity
1562303_at	0.218	2.667	2.416	2.869e-02	0.321	-3.626	ZKSCAN3	zinc finger with KRAB and SCAN domains 3	6	28425669	AK091225	80317	6p22.1	Hs.485004	11	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
217480_x_at	0.367	5.937	2.416	2.869e-02	0.321	-3.626	IGKV1OR15-118	immunoglobulin kappa variable 1/OR15-118 pseudogene	2		M20812	339562	2p11.1		1
208119_s_at	0.495	5.278	2.416	2.870e-02	0.321	-3.627	ZNF93	zinc finger protein 93	19	19872786	NM_031218	81931	19p12	Hs.301059	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
227367_at	0.291	5.148	2.416	2.870e-02	0.321	-3.627	SLCO3A1	solute carrier organic anion transporter family, member 3A1	15	90197941, 90197941	AW976431	28232	15q26	Hs.311187	10	transporter activity ion transport membrane integral to membrane
218604_at	-0.336	7.313	-2.416	2.870e-02	0.321	-3.627	LEMD3	LEM domain containing 3	12	63849637	NM_014319	23592	12q14	Hs.718513	13	nucleotide binding DNA binding membrane fraction nucleus nuclear envelope integral to nuclear inner membrane membrane integral to membrane
221074_at	0.279	5.364	2.416	2.871e-02	0.321	-3.627	NCR2	natural cytotoxicity triggering receptor 2	6	41411505	NM_004828	9436	6p21.1	Hs.194721	16	transmembrane receptor activity plasma membrane integral to plasma membrane cellular defense response signal transduction	Natural killer cell mediated cytotoxicity
1555687_a_at	-0.224	2.257	-2.416	2.872e-02	0.321	-3.627	CLEC4C	C-type lectin domain family 4, member C	12	-7773277	AF325460	170482	12p13.2-p12.3	Hs.351812	11	binding sugar binding immune response membrane integral to membrane
1569039_s_at	0.382	2.734	2.415	2.874e-02	0.321	-3.628	ZNF677	zinc finger protein 677	19	-58430449	BC029855	342926	19q13.42	Hs.20506	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209545_s_at	0.271	5.602	2.415	2.874e-02	0.321	-3.628	RIPK2	receptor-interacting serine-threonine kinase 2	8	90839109	AF064824	8767	8q21	Hs.103755	52	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity signal transducer activity protein binding ATP binding intracellular cytoplasm cytosol protein amino acid phosphorylation inflammatory response signal transduction transferase activity LIM domain binding positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 2 signaling pathway T cell proliferation positive regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JNK cascade CARD domain binding defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of ERK1 and ERK2 cascade	Neurotrophin signaling pathway
201334_s_at	-0.460	9.319	-2.415	2.875e-02	0.321	-3.628	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	11	119713155	AB002380	23365	11q23.3	Hs.24598	26	G-protein-coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm G-protein coupled receptor protein signaling pathway intracellular signaling cascade membrane regulation of Rho protein signal transduction	Vascular smooth muscle contraction Axon guidance Regulation of actin cytoskeleton
224984_at	-0.381	7.901	-2.415	2.875e-02	0.321	-3.628	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	16	68156497	W61007	10725	16q22.1	Hs.371987	35	cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction excretion positive regulation of transcription from RNA polymerase II promoter	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
1557866_at	0.256	4.542	2.415	2.876e-02	0.321	-3.628	C9orf117	chromosome 9 open reading frame 117	9	129509091	AK094948	286207	9q34.11	Hs.652519	2
244108_at	-0.308	5.389	-2.415	2.877e-02	0.321	-3.629	SYNPO2	synaptopodin 2	4	120029443, 120029443	AL552450	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
217945_at	-0.250	10.914	-2.415	2.878e-02	0.321	-3.629	BTBD1	BTB (POZ) domain containing 1	15	-81476184	NM_025238	53339	15q24	Hs.459149	15	cytoplasmic mRNA processing body protein binding cellular_component cytoplasm biological_process modification-dependent protein catabolic process protein complex
206429_at	0.301	4.361	2.415	2.879e-02	0.321	-3.629	F2RL1	coagulation factor II (thrombin) receptor-like 1	5	76150588	NM_005242	2150	5q13	Hs.154299	138	positive regulation of leukocyte chemotaxis receptor activity G-protein coupled receptor activity receptor binding Golgi apparatus plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration thrombin receptor activity regulation of blood coagulation positive regulation of positive chemotaxis	Neuroactive ligand-receptor interaction
200714_x_at	0.266	7.818	2.414	2.879e-02	0.321	-3.629	OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	12	56374152	NM_006812	10956	12q13	Hs.527861	18	protein binding endoplasmic reticulum lumen protein ubiquitination response to endoplasmic reticulum stress
235554_x_at	-0.487	4.814	-2.414	2.883e-02	0.321	-3.631	PACRGL	PARK2 co-regulated-like	4	20311133	BE048198	133015	4p15.31	Hs.479298	5	binding
212616_at	-0.365	7.963	-2.414	2.885e-02	0.321	-3.631	CHD9	chromodomain helicase DNA binding protein 9	16	51646445	BF668950	80205	16q12.2	Hs.59159 Hs.622347	10	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription
213151_s_at	-0.330	9.516	-2.413	2.885e-02	0.321	-3.631	SEPT7	septin 7	7	35807151	AU157515	989	7p14.3-p14.1	Hs.191346 Hs.642540	23	nucleotide binding condensed chromosome kinetochore cytokinesis stress fiber structural molecule activity protein binding GTP binding nucleus cytoplasm spindle cell cycle mitosis septin complex protein heterooligomerization
220895_at	0.349	3.899	2.413	2.886e-02	0.321	-3.631	USP29	ubiquitin specific peptidase 29	19	62323320	NM_020903	57663	19q13.43	Hs.515632	4	ubiquitin thiolesterase activity cellular_component protein modification process ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
215826_x_at	0.515	5.449	2.413	2.889e-02	0.322	-3.632	ZNF835	zinc finger protein 835	19	-61866764	AK023017	90485	19q13.43	Hs.458438	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
217908_s_at	-0.394	11.028	-2.413	2.890e-02	0.322	-3.632	DCAF6	DDB1 and CUL4 associated factor 6	1	166172531	NM_018442	55827	1q24.2	Hs.435741	10	nucleus ligand-dependent nuclear receptor transcription coactivator activity
222420_s_at	-0.599	8.480	-2.413	2.890e-02	0.322	-3.633	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	7	-129260230	Z29331	7328	7q32	Hs.643548	16	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity regulation of protein metabolic process	Ubiquitin mediated proteolysis
1561951_at	0.281	3.062	2.412	2.891e-02	0.322	-3.633	SLC5A12	solute carrier family 5 (sodium/glucose cotransporter), member 12	11	-26645141	BC029048	159963	11p14.2	Hs.148907	3	transporter activity plasma membrane ion transport sodium ion transport symporter activity integral to membrane sodium ion binding
200918_s_at	-0.326	7.879	-2.412	2.892e-02	0.322	-3.633	SRPR	signal recognition particle receptor (docking protein)	11	-125638043	NM_003139	6734	11q24.3	Hs.368376	7	nucleotide binding GTPase activity receptor activity signal recognition particle binding protein binding GTP binding endoplasmic reticulum signal recognition particle receptor complex SRP-dependent cotranslational protein targeting to membrane intracellular protein transport membrane integral to membrane	Protein export
210007_s_at	-0.484	4.688	-2.412	2.892e-02	0.322	-3.633	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	2	157000210, 157001145	U36310	2820	2q24.1	Hs.512382	20	glycerol-3-phosphate dehydrogenase activity calcium ion binding mitochondrion mitochondrial inner membrane glycerol-3-phosphate metabolic process gluconeogenesis glycerol-3-phosphate dehydrogenase complex oxidoreductase activity oxidation reduction	Glycerophospholipid metabolism
226155_at	-0.588	7.343	-2.412	2.892e-02	0.322	-3.633	FAM160B1	family with sequence similarity 160, member B1	10	116571492, 116571492	AB046820	57700	10q25.3	Hs.192619	2
218788_s_at	0.424	6.379	2.412	2.893e-02	0.322	-3.633	SMYD3	SET and MYND domain containing 3	1	-243979266	NM_022743	64754	1q44	Hs.567571	18	protein binding nucleus cytoplasm methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
232416_at	0.241	2.468	2.412	2.893e-02	0.322	-3.634	BRUNOL5	bruno-like 5, RNA binding protein (Drosophila)	19	3175700, 3176482	AL390161	60680	19p13	Hs.655747	3	nucleotide binding RNA binding nucleus cytoplasm mRNA processing
1554333_at	-1.127	6.512	-2.412	2.895e-02	0.322	-3.634	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	15	76343541, 76344043, 76345614	BC031044	55466	15q25.1	Hs.513053	5	protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding
204068_at	-0.308	6.685	-2.411	2.896e-02	0.322	-3.635	STK3	serine/threonine kinase 3 (STE20 homolog, yeast)	8	-99536036	NM_006281	6788	8q22.2	Hs.492333	22	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction protein kinase cascade transferase activity positive regulation of apoptosis protein dimerization activity	MAPK signaling pathway
202254_at	0.622	4.103	2.410	2.903e-02	0.322	-3.636	SIPA1L1	signal-induced proliferation-associated 1 like 1	14	71065794	AB007900	26037	14q24.2	Hs.654657	14	molecular_function GTPase activator activity protein binding cellular_component intracellular biological_process regulation of small GTPase mediated signal transduction
212129_at	-0.338	8.006	-2.410	2.903e-02	0.322	-3.636	NIPA2	non imprinted in Prader-Willi/Angelman syndrome 2	15	-20556787	AI589507	81614	15q11.2	Hs.591003	8	protein binding membrane integral to membrane
224326_s_at	-0.469	6.486	-2.410	2.903e-02	0.322	-3.637	PCGF6	polycomb group ring finger 6	10	-105052542	AB047006	84108	10q24.33	Hs.719328	12	transcription factor activity protein binding nucleus zinc ion binding negative regulation of transcription PcG protein complex metal ion binding
207456_at	0.240	3.610	2.410	2.904e-02	0.322	-3.637	HNF4G	hepatocyte nuclear factor 4, gamma	8	76614757	NM_004133	3174	8q21.11	Hs.241529	8	transcription factor activity steroid hormone receptor activity steroid binding nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter zinc ion binding transcription activator activity sequence-specific DNA binding metal ion binding	Maturity onset diabetes of the young
243026_x_at	-0.249	7.068	-2.410	2.907e-02	0.322	-3.638	XIAP	X-linked inhibitor of apoptosis	X	122821728	BE380045	331	Xq25	Hs.356076	170	protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding	Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer
219338_s_at	0.344	3.815	2.409	2.910e-02	0.323	-3.639	LRRC49	leucine rich repeat containing 49	15	68972040	NM_017691	54839	15q23	Hs.12692	7	protein binding cytoplasm cytoskeleton microtubule
208244_at	0.245	3.691	2.409	2.910e-02	0.323	-3.639	BMP3	bone morphogenetic protein 3	4	82171142	NM_001201	651	4q21	Hs.387411	17	ossification cytokine activity extracellular region extracellular space cell-cell signaling multicellular organismal development growth factor activity cell differentiation positive regulation of transcription from RNA polymerase II promoter cartilage development
202277_at	-0.300	7.329	-2.409	2.912e-02	0.323	-3.639	SPTLC1	serine palmitoyltransferase, long chain base subunit 1	9	-93881166, -93833247	AL568804	10558	9q22.2	Hs.90458	22	serine C-palmitoyltransferase activity protein binding endoplasmic reticulum acyltransferase activity biosynthetic process membrane integral to membrane transferase activity, transferring nitrogenous groups serine C-palmitoyltransferase complex sphingolipid biosynthetic process pyridoxal phosphate binding	Sphingolipid metabolism Metabolic pathways
201774_s_at	-0.498	5.243	-2.409	2.912e-02	0.323	-3.639	NCAPD2	non-SMC condensin I complex, subunit D2	12	6473558	AK022511	9918	12p13.3	Hs.5719	14	nuclear chromosome condensin core heterodimer nucleus cytoplasm cytoplasm cell cycle mitosis mitotic chromosome condensation mitotic chromosome condensation histone binding histone binding cell division
1557057_a_at	0.226	1.972	2.408	2.916e-02	0.323	-3.641	C5orf47	chromosome 5 open reading frame 47	5	173348767	AL039665	133491	5q35.2	Hs.131469	1
233082_at	0.497	4.387	2.408	2.917e-02	0.323	-3.641	ZNF630	zinc finger protein 630	X	-47802510	AK000580	57232	Xp11.3-p11.1	Hs.650883	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212606_at	-0.356	6.864	-2.408	2.917e-02	0.323	-3.641	WDFY3	WD repeat and FYVE domain containing 3	4	-85949008, -85809722, -85809722	AL536319	23001	4q21.23	Hs.480116	10	binding zinc ion binding membrane metal ion binding
212774_at	-0.660	10.201	-2.408	2.918e-02	0.323	-3.641	ZNF238	zinc finger protein 238	1	242281183, 242283204	AJ223321	10472	1q44-qter	Hs.69997	11	negative regulation of transcription from RNA polymerase II promoter nuclear chromosome transcription factor activity protein binding intracellular nucleus transport zinc ion binding regulation of transcription metal ion binding
209492_x_at	0.344	11.523	2.407	2.922e-02	0.323	-3.642	ATP5I	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	4	-656224	BC003679	521	4p16.3	Hs.85539	14	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
209669_s_at	-0.455	9.469	-2.407	2.923e-02	0.323	-3.643	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	BC003049	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
213283_s_at	0.235	5.772	2.407	2.925e-02	0.323	-3.643	SALL2	sal-like 2 (Drosophila)	14	-21059071	BG285616	6297	14q11.1-q12	Hs.416358 Hs.719293	14	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231514_at	0.325	6.838	2.406	2.926e-02	0.323	-3.643	C1orf94	chromosome 1 open reading frame 94	1	34405210, 34415139	AA725646	84970	1p34.3	Hs.194610	5	protein binding
221280_s_at	-0.411	5.421	-2.406	2.926e-02	0.323	-3.644	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	NM_019619	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
209745_at	-0.441	6.512	-2.406	2.926e-02	0.323	-3.644	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	16	18986427	AK024291	10229	16p13.11-p12.3	Hs.157113	18	iron ion binding nucleus mitochondrion ubiquinone biosynthetic process oxidoreductase activity protein metabolic process	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
200676_s_at	-0.466	6.244	-2.406	2.928e-02	0.323	-3.644	UBE2L3	ubiquitin-conjugating enzyme E2L 3	22	20251956	NM_003347	7332	22q11.21	Hs.108104 Hs.603229 Hs.715088	38	ubiquitin ligase complex nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity enzyme binding regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
212341_at	-0.235	8.520	-2.406	2.928e-02	0.323	-3.644	YIPF6	Yip1 domain family, member 6	X	67635610	AA195936	286451	Xq12	Hs.700646 Hs.82719	10	endoplasmic reticulum membrane integral to membrane
225145_at	-0.308	5.687	-2.406	2.928e-02	0.323	-3.644	NCOA5	nuclear receptor coactivator 5	20	-44123032	AB046857	57727	20q12-q13.12	Hs.654991	8	aminoacyl-tRNA ligase activity ATP binding nucleus translation regulation of transcription
217980_s_at	0.279	9.327	2.406	2.928e-02	0.323	-3.644	MRPL16	mitochondrial ribosomal protein L16	11	-59330183	NM_017840	54948	11q12-q13.1	Hs.530734	7	structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation
228652_at	0.424	7.520	2.406	2.929e-02	0.323	-3.644	ZNF776	zinc finger protein 776	19	62949975	AI279532	284309	19q13.43	Hs.109540	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
230737_s_at	0.262	4.357	2.406	2.929e-02	0.323	-3.644	LOC387647	patched domain containing 3 pseudogene	10	29738506	AW118878	387647	10p11.23	Hs.719271	2
221944_at	-0.326	4.954	-2.406	2.930e-02	0.323	-3.645	FLJ42627	hypothetical LOC645644	16	2628983	N56912	645644	16p13.3	Hs.597810 Hs.677234	1
218159_at	-0.309	7.193	-2.406	2.930e-02	0.323	-3.645	DDRGK1	DDRGK domain containing 1	20	-3119011	NM_023935	65992	20p13	Hs.471975	4	protein binding extracellular region
212431_at	0.285	7.127	2.406	2.930e-02	0.323	-3.645	HMGXB3	HMG box domain containing 3	5	149360361	D83778	22993	5q32	Hs.719189	8	DNA binding cellular_component nucleus nucleolus biological_process kinase activity
226939_at	-0.634	6.972	-2.406	2.930e-02	0.323	-3.645	CPEB2	cytoplasmic polyadenylation element binding protein 2	4	14614619	AI202327	132864	4p15.33	Hs.656937	4	nucleotide binding RNA binding cytoplasm regulation of translation
224504_s_at	-0.261	6.374	-2.405	2.933e-02	0.323	-3.646	BUD13	BUD13 homolog (S. cerevisiae)	11	-116124097	BC006350	84811	11q23.3	Hs.437341	9
211389_x_at	0.386	5.337	2.405	2.933e-02	0.323	-3.646	KIR3DS1	killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1	19	212785	U73396	3813	19q13.4	Hs.683173	70	receptor activity plasma membrane integral to plasma membrane immune response natural killer cell activation MHC class I receptor activity
36030_at	-0.491	6.822	-2.405	2.934e-02	0.323	-3.646	IFFO1	intermediate filament family orphan 1	12	-6518954, -6518954	AL080214	25900	12p13.3	Hs.15243	7	intermediate filament
239512_at	-0.382	5.598	-2.403	2.943e-02	0.324	-3.649	SFRS4	splicing factor, arginine/serine-rich 4	1	-29346837	R05895	6429	1p35.3	Hs.469970	24	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding nucleus RNA splicing nuclear speck RNA splicing factor activity, transesterification mechanism
232488_at	0.427	6.953	2.403	2.946e-02	0.324	-3.650	AGXT2L2	alanine-glyoxylate aminotransferase 2-like 2	5	-177568146	AK023470	85007	5q35.3	Hs.248746	4	mitochondrion transaminase activity transferase activity pyridoxal phosphate binding
1563137_at	0.355	4.394	2.403	2.946e-02	0.324	-3.650	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	17	72376392, 72380323	BC041577	146664	17q25.2	Hs.144531	20	Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity metal ion binding	N-Glycan biosynthesis Metabolic pathways
229594_at	-0.370	6.287	-2.402	2.949e-02	0.324	-3.650	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	11	-18584523	AI890299	144108	11p15.1	Hs.268668 Hs.719399	2
1555420_a_at	-0.385	4.324	-2.402	2.951e-02	0.324	-3.651	KLF7	Kruppel-like factor 7 (ubiquitous)	2	-207653773	BC012919	8609	2q32	Hs.471221	9	transcription factor activity transcription coactivator activity intracellular nucleus regulation of transcription from RNA polymerase II promoter axon guidance zinc ion binding regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding dendrite morphogenesis
1553540_a_at	-0.416	6.009	-2.402	2.951e-02	0.324	-3.651	SLC29A2	solute carrier family 29 (nucleoside transporters), member 2	11	-65886567	NM_001532	3177	11q13	Hs.569017	26	nucleoside transmembrane transporter activity nucleus nucleolus plasma membrane integral to plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transport cell proliferation nucleoside transport
1559258_a_at	0.235	2.802	2.402	2.951e-02	0.324	-3.651	CXorf61	chromosome X open reading frame 61	X	-115506879	AK026566	203413	Xq23	Hs.97892	2	plasma membrane integral to membrane
202825_at	0.276	12.751	2.401	2.954e-02	0.325	-3.652	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	4	186301391	NM_001151	291	4q35	Hs.246506	57	mitochondrial genome maintenance transporter activity ATP:ADP antiporter activity protein binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane integral to plasma membrane generation of precursor metabolites and energy transport adenine transmembrane transporter activity ADP transport ATP transport membrane interspecies interaction between organisms glutamate uptake during transmission of nerve impulse	Calcium signaling pathway Parkinson's disease Huntington's disease
203364_s_at	-0.245	6.764	-2.401	2.955e-02	0.325	-3.652	KIAA0652	KIAA0652	11	46595401	NM_014741	9776	11p11.2	Hs.127403	16
211162_x_at	0.265	5.137	2.401	2.956e-02	0.325	-3.652	SCD	stearoyl-CoA desaturase (delta-9-desaturase)	10	102096761	AF116616	6319	10q24.31	Hs.558396 Hs.597496	43	stearoyl-CoA 9-desaturase activity iron ion binding endoplasmic reticulum fatty acid biosynthetic process membrane integral to membrane oxidoreductase activity nuclear membrane oxidation reduction	Biosynthesis of unsaturated fatty acids PPAR signaling pathway
216561_x_at	0.287	3.357	2.401	2.956e-02	0.325	-3.653	SOX5	SRY (sex determining region Y)-box 5	12	-23576497, -23576497, -23576497	AF032454	6660	12p12.1	Hs.657542	24	transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription
224371_at	0.202	4.366	2.401	2.957e-02	0.325	-3.653	ADAMTSL1	ADAMTS-like 1	9	18464103, 18464103	AF251058	92949	9p22.2-p22.1	Hs.522019	10	extracellular region proteinaceous extracellular matrix peptidase activity metallopeptidase activity zinc ion binding
226003_at	-0.633	6.344	-2.401	2.958e-02	0.325	-3.653	KIF21A	kinesin family member 21A	12	-37973296	AB051495	55605	12q12	Hs.374201	25	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement
211678_s_at	-0.433	8.537	-2.401	2.958e-02	0.325	-3.653	RNF114	ring finger protein 114	20	47986320	AF090934	55905	20q13.13	Hs.144949	9	protein binding intracellular multicellular organismal development spermatogenesis zinc ion binding cell differentiation metal ion binding
203056_s_at	-0.624	5.745	-2.401	2.958e-02	0.325	-3.653	PRDM2	PR domain containing 2, with ZNF domain	1	13899321, 13903936, 13903936, 13948462	AI681013	7799	1p36.21	Hs.371823	39	transcription factor activity intracellular nucleus Golgi apparatus regulation of transcription, DNA-dependent methyltransferase activity zinc ion binding transferase activity histone-lysine N-methyltransferase activity metal ion binding
207688_s_at	-0.565	4.831	-2.400	2.960e-02	0.325	-3.654	INHBC	inhibin, beta C	12	56114809	NM_005538	3626	12q13.1	Hs.632722	12	transforming growth factor beta receptor binding hormone activity extracellular region growth factor activity	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
177_at	0.238	3.783	2.400	2.960e-02	0.325	-3.654	PLD1	phospholipase D1, phosphatidylcholine-specific	3	-172801311	U38545	5337	3q26	Hs.382865	84	phospholipase D activity protein binding cytoplasm endosome endoplasmic reticulum Golgi apparatus chemotaxis cell communication Ras protein signal transduction metabolic process membrane lipid catabolic process hydrolase activity phosphoinositide binding perinuclear region of cytoplasm NAPE-specific phospholipase D activity	Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways Endocytosis Fc gamma R-mediated phagocytosis GnRH signaling pathway Pathways in cancer Pancreatic cancer
1552296_at	0.300	3.510	2.400	2.961e-02	0.325	-3.654	BEST4	bestrophin 4	1	-45021843	NM_153274	266675	1p33-p32.3	Hs.302513	7	molecular_function ion channel activity chloride channel activity calcium ion binding plasma membrane ion transport biological_process integral to membrane chloride ion binding chloride channel complex
205856_at	-0.672	5.345	-2.400	2.961e-02	0.325	-3.654	SLC14A1	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)	18	41558089, 41560915	NM_015865	6563	18q11-q12	Hs.101307	27	plasma membrane integral to plasma membrane transport urea transmembrane transporter activity urea transport ubiquitin-ubiquitin ligase activity
1552789_at	-0.414	4.295	-2.399	2.970e-02	0.325	-3.657	SEC62	SEC62 homolog (S. cerevisiae)	3	171167273	NM_153039	7095	3q26.2	Hs.622596	10	receptor activity endoplasmic reticulum cytoskeleton cotranslational protein targeting to membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport
212184_s_at	-0.543	7.951	-2.399	2.970e-02	0.325	-3.657	MAP3K7IP2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	6	149680755	AL117407	23118	6q25.1-q25.3	Hs.269775	39	protein binding intracellular cytoplasm cytosol cytosol zinc ion binding membrane positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway Toll-like receptor signaling pathway
1553169_at	-0.370	4.513	-2.399	2.971e-02	0.325	-3.657	LRRN4	leucine rich repeat neuronal 4	20	-5969424	BC019612	164312	20p12.3	Hs.149133 Hs.716060	6	protein binding membrane integral to membrane
228905_at	-0.492	7.869	-2.399	2.971e-02	0.325	-3.657	PCM1	pericentriolar material 1	8	17824645	BE672700	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
232986_at	0.329	3.869	2.398	2.971e-02	0.325	-3.657	ZNF233	zinc finger protein 233	19	49455915	AC074331	353355	19q13.31	Hs.466891	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
234376_at	0.287	4.981	2.398	2.972e-02	0.325	-3.657	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	2	15998133	M55330	4613	2p24.1	Hs.25960	115	chromatin transcription factor activity protein binding nucleus regulation of transcription from RNA polymerase II promoter
227951_s_at	0.471	5.800	2.398	2.974e-02	0.325	-3.658	FAM98C	family with sequence similarity 98, member C	19	43585614	AW338561	147965	19q13.2	Hs.355162	2
221922_at	-0.819	5.746	-2.398	2.974e-02	0.325	-3.658	GPSM2	G-protein signaling modulator 2 (AGS3-like, C. elegans)	1	109221125	AW195581	29899	1p13.3	Hs.584901	11	GTPase activator activity nucleus nucleolus cytoplasm Golgi apparatus cell cortex signal transduction G-protein coupled receptor protein signaling pathway identical protein binding
217250_s_at	0.288	2.913	2.398	2.975e-02	0.325	-3.658	CHD5	chromodomain helicase DNA binding protein 5	1	-6084439	AL110281	26038	1p36.31	Hs.522898	15	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus chromatin assembly or disassembly ATP-dependent helicase activity zinc ion binding chromatin modification hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides regulation of transcription metal ion binding
1553727_at	0.306	6.414	2.398	2.975e-02	0.325	-3.658	B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3	12	439803	NM_173593	283358	12p13.33	Hs.504416	6	Golgi apparatus membrane integral to membrane transferase activity Golgi cisterna membrane N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
242271_at	1.931	6.742	2.398	2.976e-02	0.325	-3.658	SLC26A9	solute carrier family 26, member 9	1	-204148801, -204148801	AI932662	115019	1q31-q32	Hs.164073	8	transporter activity transport chloride transport regulation of pH secondary active sulfate transmembrane transporter activity sulfate transport bicarbonate transmembrane transporter activity anion:anion antiporter activity bicarbonate transport membrane integral to membrane apical plasma membrane
203870_at	0.501	7.329	2.398	2.976e-02	0.325	-3.659	USP46	ubiquitin specific peptidase 46	4	-53151885, -53151885	BE856374	64854	4q12	Hs.7966	10	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding ubiquitin-dependent protein catabolic process behavior peptidase activity cysteine-type peptidase activity protein deubiquitination regulation of synaptic transmission, GABAergic
207431_s_at	-0.525	6.882	-2.398	2.977e-02	0.325	-3.659	DEGS1	degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)	1	222437550	NM_003676	8560	1q42.11	Hs.299878	5	protein binding membrane fraction endoplasmic reticulum integral to plasma membrane unsaturated fatty acid biosynthetic process electron carrier activity membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidation reduction	Sphingolipid metabolism Metabolic pathways
235195_at	-0.625	5.787	-2.397	2.978e-02	0.325	-3.659	FBXW2	F-box and WD repeat domain containing 2	9	-122559074	BG109988	26190	9q34	Hs.494985	12	ubiquitin-protein ligase activity protein binding cytoplasm protein modification process proteolysis modification-dependent protein catabolic process
203826_s_at	0.307	6.287	2.397	2.978e-02	0.325	-3.659	PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	11	-67015815	NM_004910	9600	11q13	Hs.372295	17	calcium ion binding intracellular membrane fraction cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process brain development phototransduction phosphatidylinositol transporter activity monolayer-surrounded lipid storage body protein transport membrane
59999_at	-0.340	7.583	-2.397	2.978e-02	0.325	-3.659	HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	10	102285630	W37897	55662	10q24	Hs.500788	30	peptide-aspartate beta-dioxygenase activity iron ion binding protein binding nucleus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
207089_at	-1.281	6.766	-2.397	2.982e-02	0.325	-3.660	NRAP	nebulin-related anchoring protein	10	-115338572	AF005213	4892	10q24-q26	Hs.268788	14	actin binding actin binding protein binding fascia adherens muscle tendon junction biological_process zinc ion binding metal ion binding muscle alpha-actinin binding
223940_x_at	-0.767	8.680	-2.397	2.982e-02	0.325	-3.660	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AF132202	378938	11q13.1	Hs.642877 Hs.714394	8
201595_s_at	-0.364	8.667	-2.396	2.983e-02	0.325	-3.661	ZC3H15	zinc finger CCCH-type containing 15	2	187059129	NM_018471	55854	2q32.1	Hs.368598	3	nucleic acid binding nucleus cytoplasm zinc ion binding cytokine-mediated signaling pathway metal ion binding
208353_x_at	0.381	10.860	2.396	2.983e-02	0.325	-3.661	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_020480	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
241221_at	0.277	4.792	2.396	2.984e-02	0.325	-3.661	SEC14L3	SEC14-like 3 (S. cerevisiae)	22	-29185216	BE644691	266629	22q12.2	Hs.505601	6	transporter activity intracellular transport lipid binding
222291_at	-0.431	4.141	-2.396	2.987e-02	0.325	-3.662	FAM149A	family with sequence similarity 149, member A	4	187302988, 187307320	AI478795	25854	4q35.1	Hs.357025	3
218582_at	-0.522	7.441	-2.396	2.988e-02	0.325	-3.662	MARCH5	membrane-associated ring finger (C3HC4) 5	10	94040899	NM_017824	54708	10q23.32-q23.33	Hs.573490	8	mitochondrion mitochondrial outer membrane zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
77508_r_at	0.376	6.666	2.396	2.988e-02	0.325	-3.662	RABEP2	rabaptin, RAB GTPase binding effector protein 2	16	-28823242	AW001436	79874	16p11.2	Hs.555978	6	GTPase activator activity cytoplasm early endosome endocytosis growth factor activity protein transport
34210_at	0.437	3.347	2.396	2.988e-02	0.325	-3.662	CD52	CD52 molecule	1	26516997	N90866	1043	1p36	Hs.276770	27	membrane fraction plasma membrane integral to plasma membrane elevation of cytosolic calcium ion concentration anchored to membrane respiratory burst
212480_at	-0.231	6.843	-2.395	2.989e-02	0.325	-3.662	CYTSA	cytospin A	22	22996785	AB002374	23384	22q11.23	Hs.474384	6	cell cycle cell division
1555981_at	0.226	3.952	2.395	2.989e-02	0.325	-3.662	C17orf65	chromosome 17 open reading frame 65	17	-39608877	AK055685	339201	17q21.31	Hs.656564	2
210013_at	0.362	5.554	2.395	2.989e-02	0.325	-3.663	HPX	hemopexin	11	-6408843	BC005395	3263	11p15.5-p15.4	Hs.426485	43	positive regulation of immunoglobulin production positive regulation of humoral immune response mediated by circulating immunoglobulin binding iron ion binding extracellular region extracellular space transport cellular iron ion homeostasis heme transporter activity heme transport hemoglobin metabolic process heme metabolic process positive regulation of tyrosine phosphorylation of Stat1 protein interspecies interaction between organisms metal ion binding regulation of protein metabolic process positive regulation of response to interferon-gamma positive regulation of interferon-gamma-mediated signaling pathway
203455_s_at	-0.383	7.135	-2.395	2.990e-02	0.325	-3.663	SAT1	spermidine/spermine N1-acetyltransferase 1	X	23711195	NM_002970	6303	Xp22.1	Hs.28491	46	diamine N-acetyltransferase activity protein binding intracellular cytoplasm metabolic process acyltransferase activity transferase activity	Arginine and proline metabolism Metabolic pathways
226233_at	-0.524	8.307	-2.395	2.991e-02	0.325	-3.663	B3GALNT2	beta-1,3-N-acetylgalactosaminyltransferase 2	1	-233677155	BG112197	148789	1q42.3	Hs.716571	5	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups
220678_at	0.257	4.642	2.395	2.991e-02	0.325	-3.663	FLJ20712	hypothetical FLJ20712	7		NM_017937	55025	7p14.3	Hs.272195	3
202166_s_at	-0.630	9.095	-2.395	2.992e-02	0.325	-3.663	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	3	-196722511	NM_006241	5504	3q29	Hs.535731 Hs.706920	22	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy regulation of signal transduction regulation of phosphoprotein phosphatase activity
230433_at	0.255	4.393	2.395	2.993e-02	0.326	-3.664	LOC729970	similar to hCG2028352	1		BE857101	729970	1p21.3
204152_s_at	0.270	4.888	2.394	2.995e-02	0.326	-3.664	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	22	-36195048	AI738965	4242	22q12	Hs.517603	15	extracellular space Golgi apparatus pattern specification process membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Notch signaling pathway
218428_s_at	0.442	8.206	2.394	2.996e-02	0.326	-3.664	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	NM_016316	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
214072_x_at	0.280	5.426	2.394	2.996e-02	0.326	-3.664	NENF	neuron derived neurotrophic factor	1	210672851	AA679297	29937	1q32.3	Hs.461787	7	extracellular region extracellular space growth factor activity heme binding positive regulation of MAPKKK cascade metal ion binding
232707_at	0.379	3.685	2.394	2.996e-02	0.326	-3.665	ISX	intestine-specific homeobox	22	33792129	AK025181	91464	22q12.3	Hs.567637	2	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
218036_x_at	-0.458	5.265	-2.394	2.997e-02	0.326	-3.665	NMD3	NMD3 homolog (S. cerevisiae)	3	162421792	NM_015938	51068	3q26.1	Hs.598836	8	nucleus nucleoplasm nucleolus cytoplasm protein transport
232138_at	0.569	6.634	2.394	2.998e-02	0.326	-3.665	MBNL2	muscleblind-like 2 (Drosophila)	13	96672574	AW276914	10150	13q32.1	Hs.657347	9	RNA binding nucleus cytoplasm zinc ion binding metal ion binding
1559510_at	0.226	2.090	2.394	2.999e-02	0.326	-3.665	BHLHB9	basic helix-loop-helix domain containing, class B, 9	X	101862297, 101887562	BC040959	80823	Xq23	Hs.4276	6	binding nucleus cytoplasm
221814_at	0.328	4.906	2.393	3.002e-02	0.326	-3.666	GPR124	G protein-coupled receptor 124	8	37773581	BF511315	25960	8p11.23	Hs.274136	9	G-protein coupled receptor activity G-protein coupled receptor activity protein binding plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
205793_x_at	0.278	4.960	2.393	3.002e-02	0.326	-3.666	TNK1	tyrosine kinase, non-receptor, 1	17	7225088	NM_003985	8711	17p13.1	Hs.203420	10	nucleotide binding non-membrane spanning protein tyrosine kinase activity signal transducer activity protein binding ATP binding cytoplasm membrane transferase activity protein amino acid autophosphorylation
206749_at	0.345	5.072	2.393	3.003e-02	0.326	-3.667	CD1B	CD1b molecule	1	-156564363	NM_001764	910	1q22-q23	Hs.1310	38	protein binding lysosomal membrane endosome plasma membrane immune response endosome membrane integral to membrane antigen processing and presentation MHC class I protein complex	Hematopoietic cell lineage
238029_s_at	0.406	4.963	2.393	3.005e-02	0.326	-3.667	SLC16A14	solute carrier family 16, member 14 (monocarboxylic acid transporter 14)	2	-230607941	R15072	151473	2q36.3	Hs.504317	3	plasma membrane transport symporter activity integral to membrane
204966_at	0.316	4.693	2.393	3.006e-02	0.326	-3.667	BAI2	brain-specific angiogenesis inhibitor 2	1	-31965304	NM_001703	576	1p35	Hs.524138	11	plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane brain-specific angiogenesis inhibitor activity brain-specific angiogenesis inhibitor activity
1556464_a_at	0.216	6.195	2.393	3.006e-02	0.326	-3.667	C2orf72	chromosome 2 open reading frame 72	2	231610524	AF086098	257407	2q37.1	Hs.526596 Hs.551993	5	protein binding extracellular region
225869_s_at	0.293	4.208	2.392	3.006e-02	0.326	-3.667	UNC93B1	unc-93 homolog B1 (C. elegans)	11	-67515150	AW001274	81622	11q13	Hs.502989	15	membrane integral to membrane
212602_at	-0.357	4.855	-2.392	3.007e-02	0.326	-3.668	WDFY3	WD repeat and FYVE domain containing 3	4	-85949008, -85809722, -85809722	AI806395	23001	4q21.23	Hs.480116	10	binding zinc ion binding membrane metal ion binding
231454_at	0.314	4.974	2.392	3.008e-02	0.326	-3.668	PLAC4	placenta-specific 4	21	-41469027	R31094	191585	21q22.2	Hs.472492	3
214665_s_at	-0.351	9.690	-2.392	3.009e-02	0.326	-3.668	CHP	calcium binding protein P22	15	39310728	AK000095	11261	15q13.3	Hs.406234 Hs.706184	21	calcium ion binding cytoplasm potassium ion transport small GTPase mediated signal transduction potassium channel regulator activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
1557783_at	0.261	4.767	2.392	3.009e-02	0.326	-3.668	LOC100133991	similar to hCG1995169	17	40681085, 40695340	BC031942	100133991	17q21.31	Hs.668927	2
1558691_a_at	0.247	3.860	2.391	3.013e-02	0.326	-3.669	DOCK4	dedicator of cytokinesis 4	7	-111153399	AV691156	9732	7q31.1	Hs.654652	16	guanyl-nucleotide exchange factor activity protein binding membrane SH3 domain binding PDZ domain binding Rac GTPase activator activity stereocilium Rac GTPase binding
208242_at	0.377	6.346	2.391	3.014e-02	0.326	-3.670	RAX	retina and anterior neural fold homeobox	18	-55085246	NM_013435	30062	18q21.32	Hs.278957	8	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development visual perception sequence-specific DNA binding
1554471_a_at	-0.545	5.677	-2.391	3.014e-02	0.326	-3.670	ANKRD13C	ankyrin repeat domain 13C	1	-70497272	BC028840	81573	1p32.3-p31.3	Hs.105016	10	endoplasmic reticulum
203341_at	-0.468	7.997	-2.391	3.015e-02	0.326	-3.670	CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	2	-37282278	NM_005760	10153	2p22.2	Hs.135406	14	DNA binding binding nucleus transcription from RNA polymerase II promoter regulation of transcription
224812_at	0.341	9.887	2.391	3.015e-02	0.326	-3.670	HIBADH	3-hydroxyisobutyrate dehydrogenase	7	-27531585	AL577446	11112	7p15.2	Hs.406758	9	phosphogluconate dehydrogenase (decarboxylating) activity binding mitochondrion pentose-phosphate shunt valine metabolic process 3-hydroxyisobutyrate dehydrogenase activity oxidoreductase activity NAD or NADH binding oxidation reduction	Valine, leucine and isoleucine degradation Metabolic pathways
204053_x_at	-0.422	6.591	-2.391	3.015e-02	0.326	-3.670	PTEN	phosphatase and tensin homolog	10	89613174	U96180	5728	10q23.3	Hs.500466	557	regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade	Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer
224446_at	-0.381	7.126	-2.391	3.016e-02	0.326	-3.670	LLPH	LLP homolog, long-term synaptic facilitation (Aplysia)	12	-64803116	BC006002	84298	12q14.3	Hs.504820	4
1553412_at	0.310	5.456	2.391	3.017e-02	0.326	-3.671	AGBL4	ATP/GTP binding protein-like 4	1	-48771113	NM_032785	84871	1p33	Hs.551844 Hs.679809 Hs.716221	4	metallocarboxypeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
221235_s_at	-0.256	6.044	-2.390	3.018e-02	0.326	-3.671	LOC644617	hypothetical LOC644617	2		NM_030825	644617	2q12.1	Hs.592796	1
208374_s_at	-0.357	7.858	-2.390	3.020e-02	0.326	-3.671	CAPZA1	capping protein (actin filament) muscle Z-line, alpha 1	1	112963597	NM_006135	829	1p13.2	Hs.514934	21	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
206167_s_at	-0.835	7.674	-2.390	3.020e-02	0.326	-3.672	ARHGAP6	Rho GTPase activating protein 6	X	-11071437, -11065583, -11065583	NM_001174	395	Xp22.3	Hs.435291	6	SH3/SH2 adaptor activity GTPase activator activity Rho GTPase activator activity intracellular cytoplasm actin filament actin filament organization signal transduction Rho protein signal transduction SH3 domain binding actin filament polymerization regulation of GTPase activity negative regulation of stress fiber formation negative regulation of focal adhesion formation
221482_s_at	-0.438	11.038	-2.390	3.021e-02	0.326	-3.672	ARPP19	cAMP-regulated phosphoprotein, 19kDa	15	-50626723	BC003418	10776	15q21.2	Hs.512908	10	receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import
215461_at	0.262	5.758	2.389	3.025e-02	0.327	-3.673	ZNRF4	zinc and ring finger 4	19	5406425	AI807507	148066	19p13.3	Hs.126496	4	protein binding zinc ion binding membrane integral to membrane metal ion binding
38340_at	0.312	6.264	2.389	3.029e-02	0.327	-3.674	HIP1R	huntingtin interacting protein 1 related	12	121885991	AB014555	9026	12q24	Hs.524815 Hs.714965	19	actin binding protein binding cytoplasm coated pit receptor-mediated endocytosis biological_process membrane clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding perinuclear region of cytoplasm
1569522_at	0.338	8.193	2.389	3.029e-02	0.327	-3.674	LOC100132767	hypothetical LOC100132767	16		BC015443	100132767	16p11.2
200984_s_at	-0.364	10.115	-2.388	3.030e-02	0.327	-3.675	CD59	CD59 molecule, complement regulatory protein	11	-33681131, -33681131, -33681131	X16447	966	11p13	Hs.278573 Hs.709466 Hs.710641	107	protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane	Complement and coagulation cascades Hematopoietic cell lineage
204166_at	0.285	5.107	2.388	3.031e-02	0.327	-3.675	SBNO2	strawberry notch homolog 2 (Drosophila)	19	-1058632, -1058632	NM_014963	22904	19p13.3	Hs.408708	5	macrophage activation during immune response cellular_component transcription repressor activity regulation of transcription negative regulation of transcription, DNA-dependent regulation of inflammatory response
232893_at	0.248	2.700	2.388	3.032e-02	0.327	-3.675	LMBRD2	LMBR1 domain containing 2	5	-36139170	AL137370	92255	5p13.2	Hs.294103	2	membrane integral to membrane
1553993_s_at	-0.592	7.766	-2.387	3.041e-02	0.327	-3.678	MED25	mediator complex subunit 25	19	55013357	BC024312	81857	19q13.3	Hs.656639	13	nucleus regulation of transcription
208858_s_at	-0.739	7.811	-2.387	3.041e-02	0.327	-3.678	ESYT1	extended synaptotagmin-like protein 1	12	54808320	BC004998	23344	12q13.2	Hs.632729	10	membrane integral to membrane
214372_x_at	0.259	7.265	2.387	3.041e-02	0.327	-3.678	ERN2	endoplasmic reticulum to nucleus signaling 2	16	-23609126	AI732416	10595	16p12.2	Hs.592041	7	nucleotide binding magnesium ion binding endonuclease activity protein serine/threonine kinase activity ATP binding endoplasmic reticulum mRNA processing protein amino acid phosphorylation apoptosis induction of apoptosis response to stress cell cycle arrest membrane integral to membrane rRNA catabolic process negative regulation of transcription transferase activity hydrolase activity endoribonuclease activity, producing 5'-phosphomonoesters
227002_at	0.400	8.112	2.386	3.042e-02	0.327	-3.678	FAM78A	family with sequence similarity 78, member A	9	-133123285	BF515132	286336	9q34	Hs.143878 Hs.704076	5
244128_x_at	0.340	5.599	2.386	3.043e-02	0.327	-3.678	GLIS1	GLIS family zinc finger 1	1	-53744493	AA872588	148979	1p32.3	Hs.306691	6	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus nucleolus cytoplasm zinc ion binding positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
216762_at	0.290	4.361	2.386	3.043e-02	0.327	-3.678	KANK1	KN motif and ankyrin repeat domains 1	9	494702, 696895	AK025097	23189	9p24.3	Hs.306764	14	cytoplasm
209111_at	0.357	8.953	2.386	3.044e-02	0.327	-3.678	RNF5	ring finger protein 5	6	32254139, 3553349, 3361128	BC004155	6048	6p21.3	Hs.718462	21	protein binding zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
228339_at	0.379	7.373	2.386	3.044e-02	0.327	-3.679	ECSCR	endothelial cell-specific chemotaxis regulator	5	-138812143	AA181256	641700	5q31.2	Hs.483538 Hs.570903	5	angiogenesis plasma membrane chemotaxis multicellular organismal development integral to membrane cell differentiation
222908_at	0.323	4.190	2.386	3.046e-02	0.328	-3.679	FAM38B	family with sequence similarity 38, member B	18	-10660859	AW269818	63895	18p11.22	Hs.585839	1	membrane integral to membrane
234003_at	0.297	4.419	2.386	3.046e-02	0.328	-3.679	ENOX2	ecto-NOX disulfide-thiol exchanger 2	X	-129585037	AL133115	10495	Xq25-q26.2	Hs.171458	22	nucleotide binding nucleic acid binding copper ion binding extracellular region extracellular space nucleus cytoplasm cytosol cytoskeleton plasma membrane transport ultradian rhythm external side of plasma membrane protein disulfide oxidoreductase activity cell growth oxidoreductase activity electron transport chain regulation of growth
218721_s_at	-0.350	6.530	-2.386	3.047e-02	0.328	-3.679	C1orf27	chromosome 1 open reading frame 27	1	184611623	NM_017847	54953	1q25	Hs.371210	6	zinc ion binding membrane integral to membrane oxidoreductase activity
210266_s_at	-0.360	7.708	-2.385	3.049e-02	0.328	-3.680	TRIM33	tripartite motif-containing 33	1	-114736921	AF220137	51592	1p13.1	Hs.26837	12	DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding
200620_at	-0.236	9.852	-2.385	3.051e-02	0.328	-3.680	TMEM59	transmembrane protein 59	1	-54269936	NM_004872	9528	1p36-p31	Hs.523262	10	membrane integral to membrane
215222_x_at	-0.388	7.097	-2.385	3.052e-02	0.328	-3.681	MACF1	microtubule-actin crosslinking factor 1	1	39319704, 39569396	AK023406	23499	1p32-p31	Hs.580782	25	calcium ion binding calcium ion binding protein binding cytoplasm cytoplasm cytoskeleton cytoskeleton cell cycle arrest microtubule binding biological_process actin filament binding
223581_at	0.294	5.041	2.385	3.052e-02	0.328	-3.681	ZNF577	zinc finger protein 577	19	-57066361, -57066361, -57050868	BC004992	84765	19q13.41	Hs.148322	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225016_at	-0.752	4.994	-2.385	3.052e-02	0.328	-3.681	APCDD1	adenomatosis polyposis coli down-regulated 1	18	10444624	N48299	147495	18p11.22	Hs.293274	4	membrane integral to membrane
207121_s_at	-0.577	9.189	-2.385	3.052e-02	0.328	-3.681	MAPK6	mitogen-activated protein kinase 6	15	50098702	NM_002748	5597	15q21	Hs.411847	16	nucleotide binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation cell cycle signal transduction transferase activity
218449_at	-0.361	8.054	-2.385	3.053e-02	0.328	-3.681	UFSP2	UFM1-specific peptidase 2	4	-186557687	NM_018359	55325	4q35.1	Hs.508154 Hs.713548	8	peptidase activity cysteine-type peptidase activity thiolester hydrolase activity modification-dependent protein catabolic process
208620_at	-0.431	9.978	-2.384	3.055e-02	0.328	-3.682	PCBP1	poly(rC) binding protein 1	2	70168088	U24223	5093	2p13-p12	Hs.2853	42	nuclear mRNA splicing, via spliceosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm mRNA metabolic process ribonucleoprotein complex
227320_at	0.416	6.014	2.384	3.056e-02	0.328	-3.682	FAM101A	family with sequence similarity 101, member A	12	123339662	AW264333	144347	12q24.31	Hs.432901	3
218756_s_at	0.552	6.561	2.384	3.056e-02	0.328	-3.682	DHRS11	dehydrogenase/reductase (SDR family) member 11	17	32022338	NM_024308	79154	17q12	Hs.462859	5	binding extracellular region oxidoreductase activity oxidation reduction
1553642_at	0.271	6.304	2.384	3.057e-02	0.328	-3.682	C9orf163	chromosome 9 open reading frame 163	9	138497767	NM_152571	158055	9q34.3	Hs.212613	3	protein binding
223262_s_at	-0.323	6.171	-2.384	3.059e-02	0.328	-3.683	FGFR1OP2	FGFR1 oncogene partner 2	12	26982582	AI738434	26127	12p11.23	Hs.591162	5	cytoplasm
206863_x_at	0.375	4.521	2.384	3.060e-02	0.328	-3.683	HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	12	-115783409	U76376	8739	12q24.22	Hs.87247	18	protein binding induction of apoptosis negative regulation of survival gene product expression regulation of apoptosis
208006_at	0.384	4.265	2.383	3.060e-02	0.328	-3.683	FOXI1	forkhead box I1	5	169465494	NM_012188	2299	5q34	Hs.87236	9	transcription factor activity nucleus multicellular organismal development DNA bending activity transcription activator activity inner ear morphogenesis sequence-specific DNA binding positive regulation of transcription, DNA-dependent
226101_at	-0.597	5.924	-2.383	3.061e-02	0.328	-3.683	PRKCE	protein kinase C, epsilon	2	45732546	AI093546	5581	2p21	Hs.580351	178	nucleotide binding protein kinase C activity signal transducer activity ATP binding membrane fraction protein amino acid phosphorylation induction of apoptosis intracellular signaling cascade zinc ion binding transferase activity enzyme binding diacylglycerol binding metal ion binding	Vascular smooth muscle contraction Tight junction Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Type II diabetes mellitus
1564193_at	0.251	2.896	2.383	3.062e-02	0.328	-3.684	FLJ39061	hypothetical protein FLJ39061	2		AK096380	165057	2q33.1	Hs.686898	4
218973_at	-0.378	6.563	-2.383	3.062e-02	0.328	-3.684	EFTUD1	elongation factor Tu GTP binding domain containing 1	15	-80209615	NM_024580	79631	15q25.2	Hs.459114	4	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation
202876_s_at	0.318	6.644	2.383	3.063e-02	0.328	-3.684	PBX2	pre-B-cell leukemia homeobox 2	6	-32260487, -3559697, -3367476	NM_002586	5089	6p21.3	Hs.509545 Hs.718462	18	chromatin binding transcription factor activity protein binding nucleus transcription factor complex regulation of transcription, DNA-dependent proximal/distal pattern formation embryonic limb morphogenesis sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter
221730_at	-0.610	5.878	-2.383	3.064e-02	0.328	-3.684	COL5A2	collagen, type V, alpha 2	2	-189604885	NM_000393	1290	2q14-q32	Hs.445827	29	molecular_function extracellular matrix structural constituent extracellular region collagen collagen type V collagen fibril organization collagen fibril organization skin development skin development eye morphogenesis	Focal adhesion ECM-receptor interaction
1556061_at	-0.569	5.164	-2.383	3.064e-02	0.328	-3.684	RPP30	ribonuclease P/MRP 30kDa subunit	10	92621688, 92621688	AI760272	10556	10q23.31	Hs.139120	16	ribonuclease P activity ribonuclease activity protein binding nucleus nucleolar ribonuclease P complex nucleolus tRNA processing hydrolase activity
235832_at	0.247	5.050	2.382	3.071e-02	0.328	-3.686	NKX6-2	NK6 homeobox 2	10	-134448309	BF509028	84504	10q26	Hs.134013	2	negative regulation of transcription from RNA polymerase II promoter transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development negative regulation of cell fate commitment positive regulation of cell fate commitment regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification myelination in the central nervous system cell differentiation endocrine pancreas development sequence-specific DNA binding negative regulation of glial cell differentiation positive regulation of glial cell differentiation oligodendrocyte differentiation neuromuscular process controlling balance
201232_s_at	-0.425	8.368	-2.381	3.073e-02	0.329	-3.687	PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	11	226807	NM_002817	5719	11p15.5	Hs.134688	41	proteasome complex protein binding cytosol proteasome regulatory particle meiosis I anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
232588_at	0.322	4.360	2.381	3.076e-02	0.329	-3.688	STAG1	stromal antigen 1	3	-137538688	AI038943	10274	3q22.3	Hs.412586	11	chromatin protein binding nucleus cell cycle chromosome segregation mitosis cell division	Cell cycle
215393_s_at	0.292	4.343	2.381	3.077e-02	0.329	-3.688	COBLL1	COBL-like 1	2	-165249503	AK002054	22837	2q24.3	Hs.470457	9
212667_at	-0.498	9.178	-2.380	3.078e-02	0.329	-3.688	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	5	-151021201	AL575922	6678	5q31.3-q32	Hs.111779 Hs.708558	115	ossification copper ion binding calcium ion binding collagen binding extracellular region extracellular region basement membrane signal transduction platelet alpha granule lumen regulation of cell proliferation extracellular matrix binding
1565660_at	0.344	5.656	2.380	3.079e-02	0.329	-3.689	FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	19	-5781636	BC040472	2528	19p13.3	Hs.631846 Hs.705615	19	Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
241827_at	0.406	6.408	2.380	3.081e-02	0.329	-3.689	ZNF615	zinc finger protein 615	19	-57186399	AL577866	284370	19q13.41	Hs.368355	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202808_at	-0.429	7.423	-2.379	3.084e-02	0.329	-3.690	C10orf26	chromosome 10 open reading frame 26	10	104493716, 104525877	AK000161	54838	10q24.32	Hs.500897 Hs.693257 Hs.707763	9	membrane integral to membrane
212623_at	-0.445	6.618	-2.379	3.085e-02	0.329	-3.690	TMEM41B	transmembrane protein 41B	11	-9258777	AU153138	440026	11p15.4	Hs.594563	4	membrane integral to membrane
231867_at	1.306	3.793	2.379	3.086e-02	0.329	-3.691	ODZ2	odz, odd Oz/ten-m homolog 2 (Drosophila)	5	166644420	AB032953	57451	5q34	Hs.654631 Hs.715483	9	signal transduction membrane integral to membrane
222879_s_at	0.284	4.820	2.379	3.087e-02	0.329	-3.691	POLH	polymerase (DNA directed), eta	6	43651855	AF158185	5429	6p21.1	Hs.655467	65	magnesium ion binding DNA synthesis during DNA repair damaged DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm nucleolus cytoplasm regulation of DNA repair pyrimidine dimer repair postreplication repair response to DNA damage stimulus response to UV-C transferase activity nucleotidyltransferase activity
1570344_at	0.289	4.362	2.379	3.088e-02	0.329	-3.691	LRPPRC	leucine-rich PPR-motif containing	2	-43966866	BG772870	10128	2p21	Hs.368084	15	condensed nuclear chromosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus nuclear inner membrane nuclear outer membrane nucleoplasm cytoplasm mitochondrion cytoskeleton transport microtubule binding membrane mitochondrial nucleoid regulation of transcription mitochondrion transport along microtubule perinuclear region of cytoplasm beta-tubulin binding actin filament binding mRNA transport
230102_at	-0.557	3.959	-2.379	3.088e-02	0.329	-3.691	ETV5	ets variant 5	3	-187246799	AW206458	2119	3q28	Hs.43697	21	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
236846_at	0.543	3.810	2.378	3.090e-02	0.329	-3.692	LOC284757	hypothetical protein LOC284757	20		AI808031	284757	20q13.33	Hs.656468	1
236656_s_at	-0.887	6.679	-2.378	3.091e-02	0.329	-3.692	LOC100130506	hypothetical protein LOC100130506	2		AW014647	100130506
229877_at	0.228	2.554	2.378	3.094e-02	0.330	-3.693	NEO1	neogenin homolog 1 (chicken)	15	71131927	BF058828	4756	15q22.3-q23	Hs.388613	17	protein binding plasma membrane integral to plasma membrane cell adhesion	Cell adhesion molecules (CAMs)
231919_at	-0.382	6.052	-2.378	3.094e-02	0.330	-3.693	DBT	dihydrolipoamide branched chain transacylase E2	1	-100425065	AK024946	1629	1p31	Hs.709187	34	protein binding mitochondrion mitochondrial alpha-ketoglutarate dehydrogenase complex metabolic process acyltransferase activity transferase activity lipoic acid binding mitochondrial nucleoid dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity acyl-CoA biosynthetic process cofactor binding	Valine, leucine and isoleucine degradation Metabolic pathways
209694_at	-0.301	9.325	-2.377	3.097e-02	0.330	-3.694	PTS	6-pyruvoyltetrahydropterin synthase	11	111602297	M97655	5805	11q22.3-q23.3	Hs.503860	42	6-pyruvoyltetrahydropterin synthase activity cytoplasm mitochondrion cellular amino acid metabolic process tetrahydrobiopterin biosynthetic process central nervous system development zinc ion binding lyase activity protein homodimerization activity metal ion binding	Folate biosynthesis Metabolic pathways
227674_at	0.386	5.421	2.377	3.097e-02	0.330	-3.694	ZNF585A	zinc finger protein 585A	19	-42332840, -42332840	AA910852	199704	19q13.12	Hs.390568 Hs.659236	3	nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
242345_at	-0.726	3.395	-2.377	3.098e-02	0.330	-3.694	COL28A1	collagen, type XXVIII, alpha 1	7	-7364768	AI217375	340267	7p21.3	Hs.491104	3	serine-type endopeptidase inhibitor activity protein binding extracellular region basement membrane cell adhesion peptidase inhibitor activity
225217_s_at	-0.438	5.673	-2.377	3.099e-02	0.330	-3.694	BRPF3	bromodomain and PHD finger containing, 3	6	36272527	AB033112	27154	6p21	Hs.520096	6	histone acetyltransferase complex protein binding zinc ion binding histone H3 acetylation metal ion binding
202187_s_at	-0.450	8.106	-2.377	3.100e-02	0.330	-3.694	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha isoform	1	210525501	NM_006243	5525	1q32.2-q32.3	Hs.716433	41	protein phosphatase type 2A complex chromosome, centromeric region protein binding nucleus cytoplasm signal transduction protein phosphatase type 2A regulator activity	Wnt signaling pathway
234129_at	-0.249	3.328	-2.376	3.107e-02	0.330	-3.696	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	11	119713155	AL137456	23365	11q23.3	Hs.24598	26	G-protein-coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm G-protein coupled receptor protein signaling pathway intracellular signaling cascade membrane regulation of Rho protein signal transduction	Vascular smooth muscle contraction Axon guidance Regulation of actin cytoskeleton
220228_at	-0.276	2.809	-2.376	3.107e-02	0.330	-3.697	AP4E1	adaptor-related protein complex 4, epsilon 1 subunit	15	48988237	AB030653	23431	15q21.2	Hs.413366	6	structural molecule activity protein binding Golgi apparatus intracellular protein transport vesicle-mediated transport membrane coat COPI vesicle coat	Lysosome
207974_s_at	-0.312	10.662	-2.375	3.109e-02	0.331	-3.697	SKP1	S-phase kinase-associated protein 1	5	-133519980	NM_006930	6500	5q31	Hs.171626 Hs.710433	63	protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
215245_x_at	-0.438	6.486	-2.375	3.110e-02	0.331	-3.697	FMR1	fragile X mental retardation 1	X	146801200	AA830884	2332	Xq27.3	Hs.103183	211	mRNA binding protein binding soluble fraction nucleus nucleoplasm nucleolus cytoplasm transport polysomal ribosome mRNA transport
206698_at	-0.707	6.422	-2.375	3.112e-02	0.331	-3.698	XK	X-linked Kx blood group (McLeod syndrome)	X	37430051	NM_021083	7504	Xp21.1	Hs.78919	24	transporter activity protein binding transport amino acid transport membrane integral to membrane
212229_s_at	-0.481	8.773	-2.374	3.115e-02	0.331	-3.699	FBXO21	F-box protein 21	12	-116065967	AK001699	23014	12q24.22	Hs.719089	7	ubiquitin ligase complex ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process
209210_s_at	-0.267	9.057	-2.374	3.115e-02	0.331	-3.699	FERMT2	fermitin family homolog 2 (Drosophila)	14	-52395956, -52393739	Z24725	10979	14q22.1	Hs.509343	12	stress fiber protein binding cytoplasm cytoskeleton focal adhesion cell cortex cell adhesion regulation of cell shape actin cytoskeleton organization cell junction filamentous actin
224976_at	-0.413	7.460	-2.374	3.116e-02	0.331	-3.699	NFIA	nuclear factor I/A	1	61315533, 61320121, 61320567	R37335	4774	1p31.3-p31.2	Hs.594180 Hs.710546	20	transcription factor activity intracellular nucleus nucleus cytoplasm plasma membrane DNA replication regulation of transcription, DNA-dependent transcription factor binding viral genome replication
222223_s_at	0.253	3.717	2.374	3.117e-02	0.331	-3.700	IL1F5	interleukin 1 family, member 5 (delta)	2	113532685, 113533155	AF216693	26525	2q14	Hs.516301	28	cytokine activity interleukin-1 receptor antagonist activity extracellular region extracellular space immune response
240633_at	0.576	7.609	2.374	3.119e-02	0.331	-3.700	DOK7	docking protein 7	4	3434830	AI743416	285489	4p16.3	Hs.122110 Hs.701584	11	insulin receptor binding plasma membrane cell junction synapse
228536_at	-0.349	5.287	-2.374	3.120e-02	0.331	-3.700	PRMT10	protein arginine methyltransferase 10 (putative)	4	-148778982	AA574240	90826	4q31.23	Hs.591692	4	binding
210981_s_at	0.311	7.074	2.374	3.120e-02	0.331	-3.700	GRK6	G protein-coupled receptor kinase 6	5	176786292, 176786292	AF040751	2870	5q35	Hs.235116	31	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity ATP binding protein amino acid phosphorylation signal transduction regulation of G-protein coupled receptor protein signaling pathway membrane transferase activity	Chemokine signaling pathway Endocytosis
234676_s_at	-0.248	3.348	-2.373	3.120e-02	0.331	-3.700	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)	21	-29166383	AK021678	29104	21q21.3	Hs.163846	6	nucleic acid binding protein binding protein methyltransferase activity transferase activity positive regulation of cell growth methylation protein complex
213069_at	-0.507	7.849	-2.373	3.123e-02	0.331	-3.701	HEG1	HEG homolog 1 (zebrafish)	3	-126167243	AI148659	57493	3q21.2	Hs.477420	4	calcium ion binding extracellular region membrane integral to membrane
231906_at	-0.803	5.469	-2.373	3.124e-02	0.331	-3.701	HOXD8	homeobox D8	2	176702722	BF057634	3234	2q31.1	Hs.301963 Hs.700870	14	negative regulation of transcription from RNA polymerase II promoter transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development determination of anterior/posterior axis, embryo anterior/posterior pattern formation sequence-specific DNA binding skeletal system morphogenesis
226338_at	-0.548	6.736	-2.372	3.127e-02	0.331	-3.702	TMEM55A	transmembrane protein 55A	8	-92075674	AA604382	55529	8q21.3	Hs.202517	4	lysosome endosome membrane integral to membrane hydrolase activity
91826_at	0.298	5.153	2.372	3.127e-02	0.331	-3.702	EPS8L1	EPS8-like 1	19	60279032, 60283571	AI219073	54869	19q13.42	Hs.438862	8	molecular_function cellular_component cytoplasm biological_process
205054_at	-0.214	13.427	-2.372	3.128e-02	0.331	-3.703	NEB	nebulin	2	-152050098	NM_004543	4703	2q22	Hs.588655	32	actin binding protein binding cytoplasm somatic muscle development structural constituent of muscle actin cytoskeleton sarcomere Z disc regulation of actin filament length
1563860_at	0.258	3.725	2.372	3.129e-02	0.331	-3.703	LOC400965	hypothetical LOC400965	2		AK098018	400965	2p11.2	Hs.646791	1
218239_s_at	-0.574	7.457	-2.372	3.129e-02	0.331	-3.703	GTPBP4	GTP binding protein 4	10	1024348	NM_012341	23560	10p15-p14	Hs.215766	10	regulation of cyclin-dependent protein kinase activity nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization
204033_at	0.418	3.779	2.372	3.130e-02	0.331	-3.703	TRIP13	thyroid hormone receptor interactor 13	5	946003	NM_004237	9319	5p15.33	Hs.436187	10	nucleotide binding transcription cofactor activity ATP binding nucleus transcription from RNA polymerase II promoter nucleoside-triphosphatase activity identical protein binding
206516_at	0.316	4.538	2.372	3.130e-02	0.331	-3.703	AMH	anti-Mullerian hormone	19	2200112	NM_000479	268	19p13.3	Hs.112432	75	urogenital system development Mullerian duct regression transforming growth factor beta receptor binding hormone activity extracellular region extracellular space cytoplasm cell-cell signaling gonadal mesoderm development sex determination sex differentiation growth factor activity cell differentiation	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
232946_s_at	-0.386	5.008	-2.372	3.130e-02	0.331	-3.703	NADSYN1	NAD synthetase 1	11	70841864	AL512694	55191	11q13.4	Hs.556986	9	nucleotide binding NAD+ synthase (glutamine-hydrolyzing) activity NAD+ synthase (glutamine-hydrolyzing) activity protein binding ATP binding cytosol nitrogen compound metabolic process NAD biosynthetic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ligase activity	Nicotinate and nicotinamide metabolism Metabolic pathways
214172_x_at	-0.326	5.901	-2.371	3.133e-02	0.331	-3.704	RYK	RYK receptor-like tyrosine kinase	3	-135358667	BG032035	6259	3q22	Hs.654562	13	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction axonogenesis transferase activity Wnt-protein binding Wnt receptor activity skeletal system morphogenesis
219561_at	-0.567	8.341	-2.371	3.134e-02	0.331	-3.704	COPZ2	coatomer protein complex, subunit zeta 2	17	-43458531	NM_016429	51226	17q21.32	Hs.408434	8	protein binding cytoplasm Golgi apparatus cis-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat COPI vesicle coat cytoplasmic vesicle
226327_at	-0.407	7.024	-2.371	3.135e-02	0.331	-3.704	ZNF507	zinc finger protein 507	19	37528353	N64593	22847	19q13.11	Hs.205392	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
213782_s_at	-1.156	11.420	-2.371	3.135e-02	0.331	-3.705	MYOZ2	myozenin 2	4	120276386	BF939176	51778	4q26-q27	Hs.381047	16	protein binding cytoplasm biological_process actin cytoskeleton sarcomere Z disc protein phosphatase 2B binding
205376_at	-0.976	4.882	-2.371	3.138e-02	0.332	-3.705	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	4	-143168631	NM_003866	8821	4q31.21	Hs.658245	9	signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
226916_x_at	-0.264	6.304	-2.370	3.139e-02	0.332	-3.706	DPP9	dipeptidyl-peptidase 9	19	-4626243	AW190431	91039	19p13.3	Hs.515081	14	aminopeptidase activity cytoplasm cytosol proteolysis peptidase activity serine-type peptidase activity membrane
223879_s_at	-0.623	7.518	-2.370	3.143e-02	0.332	-3.707	OXR1	oxidation resistance 1	8	107351648, 107739211	AF309387	55074	8q23	Hs.148778	11	molecular_function cellular_component nucleolus mitochondrion response to oxidative stress cell wall macromolecule catabolic process
202429_s_at	-0.573	8.493	-2.370	3.144e-02	0.332	-3.707	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	AL353950	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
219992_at	0.408	5.794	2.369	3.145e-02	0.332	-3.707	TAC3	tachykinin 3	12	-55690050	NM_013251	6866	12q13-q21	Hs.9730	26	receptor binding extracellular region extracellular space soluble fraction tachykinin receptor signaling pathway neuropeptide signaling pathway female pregnancy
200694_s_at	-0.221	8.904	-2.369	3.145e-02	0.332	-3.707	DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	14	-93587020	NM_020414	57062	14q32	Hs.510328	20	nucleotide binding RNA binding ATP-dependent RNA helicase activity ATP binding cellular_component nucleolus cytoplasm RNA metabolic process hydrolase activity
224753_at	0.263	5.010	2.369	3.145e-02	0.332	-3.707	CDCA5	cell division cycle associated 5	11	-64601502	BE614410	113130	11q12.1	Hs.434886	11	G1/S transition of mitotic cell cycle chromatin binding protein binding nucleus cytoplasm cell cycle mitosis mitotic chromosome condensation mitotic metaphase plate congression cohesin complex cell division
200020_at	-0.452	8.553	-2.369	3.146e-02	0.332	-3.707	TARDBP	TAR DNA binding protein	1	10995265	NM_007375	23435	1p36.22	Hs.300624 Hs.635053 Hs.716809	92	nucleotide binding transcription factor activity RNA binding protein binding nucleus nucleolus transcription from RNA polymerase II promoter mRNA processing mitosis microtubule binding cell death RNA splicing regulation of transcription
202250_s_at	-0.517	8.116	-2.369	3.146e-02	0.332	-3.708	DCAF8	DDB1 and CUL4 associated factor 8	1	-158475636, -158475636, -158452128, -158452128	NM_015726	50717	1q22-q23	Hs.632447	10	protein binding
235980_at	-0.451	5.834	-2.369	3.147e-02	0.332	-3.708	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	3	180349004	AA767763	5290	3q26.3	Hs.553498 Hs.85701	259	nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex glucose metabolic process protein amino acid phosphorylation anti-apoptosis signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor lamellipodium regulation of multicellular organism growth protein kinase B signaling cascade insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
235033_at	-0.387	5.786	-2.369	3.148e-02	0.332	-3.708	NPEPL1	aminopeptidase-like 1	20	56701267	AL577823	79716	20q13.32	Hs.554211 Hs.654868	7	aminopeptidase activity intracellular proteolysis peptidase activity zinc ion binding manganese ion binding metal ion binding
218528_s_at	-0.422	7.022	-2.368	3.151e-02	0.332	-3.709	RNF38	ring finger protein 38	9	-36326398, -36326398, -36326398	NM_022781	152006	9p13	Hs.333503	12	protein binding zinc ion binding metal ion binding
231525_at	0.314	3.843	2.368	3.153e-02	0.332	-3.710	IQCF5	IQ motif containing F5	3	-51882777	AI377780	389124	3p21.2	Hs.666604	1
200609_s_at	-0.303	8.777	-2.368	3.154e-02	0.332	-3.710	WDR1	WD repeat domain 1	4	-9685060	NM_017491	9948	4p16.1	Hs.128548 Hs.713658	15	actin binding protein binding cytoplasm cytoskeleton sensory perception of sound
211359_s_at	0.268	2.971	2.368	3.154e-02	0.332	-3.710	OPRM1	opioid receptor, mu 1	6	154373328, 154402135, 154402135, 154402135, 154402135, 154402135, 154402135, 154402135, 154402238, 154449334	U12569	4988	6q24-q25	Hs.2353	192	receptor activity G-protein coupled receptor activity mu-opioid receptor activity endoplasmic reticulum Golgi apparatus plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger sensory perception behavior negative regulation of cell proliferation	Neuroactive ligand-receptor interaction
200850_s_at	-0.487	8.902	-2.368	3.154e-02	0.332	-3.710	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	NM_006621	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
204513_s_at	0.292	5.170	2.368	3.156e-02	0.332	-3.710	ELMO1	engulfment and cell motility 1	7	-36860485, -36860485, -36860485	NM_014800	9844	7p14.2-p14.1	Hs.656638	29	protein binding cytoplasm cytosol cytoskeleton plasma membrane phagocytosis, engulfment apoptosis cell motion Rac protein signal transduction SH3 domain binding actin cytoskeleton organization	Chemokine signaling pathway
220552_at	0.220	2.509	2.367	3.158e-02	0.332	-3.711	TRPC5	transient receptor potential cation channel, subfamily C, member 5	X	-110904197	NM_012471	7224	Xq23	Hs.657709	27	ion channel activity calcium ion binding protein binding integral to plasma membrane ion transport calcium ion transport nervous system development store-operated calcium channel activity membrane
203557_s_at	0.394	7.550	2.367	3.158e-02	0.332	-3.711	PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	10	-72313272	NM_000281	5092	10q22	Hs.3192	28	transcription coactivator activity phenylalanine 4-monooxygenase activity nucleus cytoplasm tetrahydrobiopterin biosynthetic process 4-alpha-hydroxytetrahydrobiopterin dehydratase activity lyase activity identical protein binding regulation of protein homodimerization activity positive regulation of transcription protein homotetramerization protein heterooligomerization
202642_s_at	-0.419	5.955	-2.367	3.160e-02	0.332	-3.712	TRRAP	transformation/transcription domain-associated protein	7	98314048	NM_003496	8295	7q21.2-q22.1	Hs.203952 Hs.706926	40	PCAF complex transcription cofactor activity protein binding nucleus chromatin modification histone deubiquitination phosphotransferase activity, alcohol group as acceptor STAGA complex transcription factor TFTC complex NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation regulation of transcription
227197_at	0.377	3.429	2.367	3.161e-02	0.332	-3.712	SGEF	Src homology 3 domain-containing guanine nucleotide exchange factor	3	155321838	AI989530	26084	3q25.2	Hs.240845	6
203543_s_at	-0.888	7.801	-2.367	3.162e-02	0.332	-3.712	KLF9	Kruppel-like factor 9	9	-72189332	NM_001206	687	9q13	Hs.150557 Hs.602267	19	transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter embryo implantation zinc ion binding regulation of transcription metal ion binding progesterone receptor signaling pathway
218423_x_at	-0.349	6.090	-2.367	3.162e-02	0.333	-3.712	VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)	2	-63973170	NM_016516	51542	2p13-p14	Hs.48499	8	protein binding protein transport retrograde transport, endosome to Golgi
212242_at	-0.932	10.308	-2.366	3.164e-02	0.333	-3.713	TUBA4A	tubulin, alpha 4a	2	-219823244	AL565074	7277	2q35	Hs.75318	70	nucleotide binding GTPase activity structural molecule activity protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
220955_x_at	-0.400	4.974	-2.366	3.166e-02	0.333	-3.713	RAB23	RAB23, member RAS oncogene family	6	-57161540, -57161540	NM_016277	51715	6p11	Hs.555016	11	nucleotide binding GTP binding plasma membrane signal transduction small GTPase mediated signal transduction nervous system development regulation of smoothened signaling pathway protein transport spinal cord dorsal/ventral patterning embryonic digit morphogenesis negative regulation of proteolysis	Hedgehog signaling pathway
201663_s_at	-0.526	4.686	-2.366	3.166e-02	0.333	-3.713	SMC4	structural maintenance of chromosomes 4	3	161600123, 161601040	NM_005496	10051	3q26.1	Hs.58992	14	nucleotide binding condensin complex condensin complex protein binding ATP binding nucleus chromosome cytoplasm cell cycle mitotic chromosome condensation protein heterodimerization activity cell division
1559413_at	-0.401	4.591	-2.366	3.168e-02	0.333	-3.714	TCP11L2	t-complex 11 (mouse)-like 2	12	105220710	AF306858	255394	12q23.3	Hs.696047	1
204357_s_at	-0.240	6.282	-2.365	3.170e-02	0.333	-3.714	LIMK1	LIM domain kinase 1	7	73136091	NM_002314	3984	7q11.23	Hs.647035	54	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm focal adhesion protein amino acid phosphorylation signal transduction Rho protein signal transduction nervous system development zinc ion binding transferase activity actin cytoskeleton organization positive regulation of axon extension metal ion binding protein heterodimerization activity	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
1554450_s_at	-0.585	4.729	-2.365	3.171e-02	0.333	-3.714	MIER3	mesoderm induction early response 1, family member 3	5	-56251185	BC041348	166968	5q11.2	Hs.657594	7	DNA binding nucleus regulation of transcription
212112_s_at	-0.458	7.077	-2.365	3.171e-02	0.333	-3.715	STX12	syntaxin 12	1	27972280	AI816243	23673	1p35-p34.1	Hs.523855	18	SNAP receptor activity Golgi apparatus intracellular protein transport membrane integral to membrane vesicle-mediated transport cholesterol efflux membrane raft phagocytic vesicle protein stabilization	SNARE interactions in vesicular transport
232216_at	0.485	3.893	2.365	3.172e-02	0.333	-3.715	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AA828049	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
1555626_a_at	0.279	5.154	2.365	3.172e-02	0.333	-3.715	SLAMF1	signaling lymphocytic activation molecule family member 1	1	-158846514	BC012602	6504	1q22-q23	Hs.523660	36	antigen binding transmembrane receptor activity plasma membrane positive regulation of cell proliferation cell surface integral to membrane interspecies interaction between organisms lymphocyte activation
221479_s_at	-0.467	7.930	-2.365	3.172e-02	0.333	-3.715	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	8	26296439	AF060922	665	8p21	Hs.131226	19	lamin binding lamin binding nucleus nuclear envelope mitochondrion mitochondrial envelope endoplasmic reticulum induction of apoptosis negative regulation of survival gene product expression membrane integral to membrane protein homodimerization activity negative regulation of apoptosis interspecies interaction between organisms protein heterodimerization activity defense response to virus
209150_s_at	-0.271	6.611	-2.365	3.173e-02	0.333	-3.715	TM9SF1	transmembrane 9 superfamily member 1	14	-23729083, -23728192	U94831	10548	14q11.2	Hs.91586	5	membrane integral to membrane
207801_s_at	-0.420	8.803	-2.365	3.174e-02	0.333	-3.715	RNF10	ring finger protein 10	12	119456514	NM_014868	9921	12q24.31	Hs.442798	10	protein binding cytoplasm zinc ion binding positive regulation of transcription metal ion binding
202405_at	-0.434	6.053	-2.365	3.175e-02	0.333	-3.716	TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	10	-121322967	BF432532	7073	10q	Hs.501203	33	nucleotide binding RNA polymerase II transcription factor activity RNA binding lysosome regulation of transcription from RNA polymerase II promoter apoptosis induction of apoptosis defense response
212872_s_at	-0.263	6.082	-2.365	3.175e-02	0.333	-3.716	MED20	mediator complex subunit 20	6	-41981069	AK023092	9477	6p21.1	Hs.278434	11	DNA-directed RNA polymerase activity protein binding nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity mediator complex regulation of transcription
238070_at	-0.437	5.013	-2.364	3.176e-02	0.333	-3.716	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	AA573217	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
213279_at	0.372	5.807	2.364	3.176e-02	0.333	-3.716	DHRS1	dehydrogenase/reductase (SDR family) member 1	14	-23829645, -23829645	AL050217	115817	14q12	Hs.719146	13	binding nucleus cytoplasm mitochondrial inner membrane endoplasmic reticulum Golgi apparatus oxidoreductase activity oxidation reduction
209508_x_at	-0.369	7.396	-2.364	3.178e-02	0.333	-3.717	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	AF005774	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
225242_s_at	-0.801	5.742	-2.364	3.178e-02	0.333	-3.717	CCDC80	coiled-coil domain containing 80	3	-113806098	AW303375	151887	3q13.2	Hs.477128	10	fibronectin binding extracellular region basement membrane interstitial matrix heparin binding positive regulation of cell-substrate adhesion extracellular matrix organization intracellular membrane-bounded organelle
222484_s_at	0.728	8.550	2.364	3.181e-02	0.333	-3.717	CXCL14	chemokine (C-X-C motif) ligand 14	5	-134934267	AF144103	9547	5q31	Hs.483444	32	extracellular region extracellular space Golgi apparatus chemotaxis immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
226488_at	0.342	7.508	2.363	3.183e-02	0.333	-3.718	RCCD1	RCC1 domain containing 1	15	89299109	AW007826	91433	15q26.1	Hs.655895	4
208845_at	0.222	12.363	2.363	3.183e-02	0.333	-3.718	VDAC3	voltage-dependent anion channel 3	8	42368502	BC002456	7419	8p11.2	Hs.655340 Hs.699301	18	nucleotide binding behavioral fear response protein binding mitochondrion mitochondrial outer membrane mitochondrial inner membrane anion transport nerve-nerve synaptic transmission learning voltage-gated anion channel activity adenine transport membrane integral to membrane rough microsome	Calcium signaling pathway Parkinson's disease Huntington's disease
221776_s_at	-0.490	6.451	-2.363	3.184e-02	0.333	-3.718	BRD7	bromodomain containing 7	16	-48910441	AI885109	29117	16q12	Hs.437894	22	nucleus cytoplasm regulation of transcription from RNA polymerase II promoter transcription factor binding Wnt receptor signaling pathway histone binding
213742_at	-0.556	4.863	-2.363	3.184e-02	0.333	-3.718	SFRS11	splicing factor, arginine/serine-rich 11	1	70443952	AW241752	9295	1p31	Hs.479693	13	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleolus RNA splicing
221227_x_at	0.295	8.085	2.363	3.187e-02	0.333	-3.719	COQ3	coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	6	-99924068	NM_017421	51805	6q16.2	Hs.713623	6	hexaprenyldihydroxybenzoate methyltransferase activity mitochondrion mitochondrial matrix glycerol metabolic process ubiquinone biosynthetic process metabolic process O-methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity transferase activity	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
203367_at	-0.269	6.604	-2.363	3.187e-02	0.333	-3.719	DUSP14	dual specificity phosphatase 14	17	32924063	NM_007026	11072	17q12	Hs.91448	5	protein tyrosine phosphatase activity protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
223053_x_at	-0.292	8.527	-2.363	3.187e-02	0.333	-3.719	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	AF277178	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
1560746_at	-0.361	2.535	-2.362	3.189e-02	0.333	-3.719	C1orf118	chromosome 1 open reading frame 118	1		AK075118	374987	1p31.1	Hs.632414	1
213352_at	-0.713	6.674	-2.362	3.190e-02	0.333	-3.720	TMCC1	transmembrane and coiled-coil domain family 1	3	-130849324, -130849324	AB018322	23023	3q22.1	Hs.477547 Hs.709936	6	membrane integral to membrane
206394_at	-1.376	12.029	-2.362	3.190e-02	0.333	-3.720	MYBPC2	myosin binding protein C, fast type	19	55627971	NM_004533	4606	19q13.33	Hs.85937	10	actin binding protein binding striated muscle thick filament striated muscle contraction cell adhesion structural constituent of muscle
213374_x_at	-0.343	8.400	-2.362	3.191e-02	0.333	-3.720	HIBCH	3-hydroxyisobutyryl-Coenzyme A hydrolase	2	-190777604	AW000964	26275	2q32.2	Hs.656685	8	3-hydroxyisobutyryl-CoA hydrolase activity protein binding mitochondrion metabolic process branched chain family amino acid catabolic process hydrolase activity	Valine, leucine and isoleucine degradation beta-Alanine metabolism Propanoate metabolism Metabolic pathways
211784_s_at	-0.373	8.572	-2.362	3.194e-02	0.334	-3.721	SFRS1	splicing factor, arginine/serine-rich 1	17	-53433278	BC006181	6426	17q21.3-q22	Hs.68714	106	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex cytoplasm mRNA splice site selection RNA splicing nuclear speck
217766_s_at	-0.424	6.749	-2.362	3.194e-02	0.334	-3.721	TMEM50A	transmembrane protein 50A	1	25537397	NM_014313	23585	1p36.11	Hs.523054	13	cytoplasm endoplasmic reticulum membrane integral to membrane
233093_s_at	-0.298	7.946	-2.361	3.194e-02	0.334	-3.721	BIRC6	baculoviral IAP repeat-containing 6	2	32435599	AK023788	57448	2p22-p21	Hs.150107	14	ubiquitin-protein ligase activity cysteine-type endopeptidase inhibitor activity protein binding cellular_component intracellular membrane fraction apoptosis anti-apoptosis positive regulation of cell proliferation ligase activity modification-dependent protein catabolic process peptidase inhibitor activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
240106_at	-0.328	6.007	-2.361	3.196e-02	0.334	-3.721	GNPTAB	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	12	-100663407	AI633523	79158	12q23.2	Hs.46850	16	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity calcium ion binding nucleus Golgi apparatus transcription factor binding membrane integral to membrane transferase activity cell differentiation	Lysosome
211069_s_at	-0.200	9.470	-2.361	3.196e-02	0.334	-3.722	SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	2	-202779147	BC006462	7341	2q33	Hs.596171 Hs.81424	228	protein binding nucleus nuclear pore cytoplasm DNA repair membrane negative regulation of transcription negative regulation of transcription PML body nuclear speck protein sumoylation modification-dependent protein catabolic process positive regulation of protein complex assembly nuclear membrane regulation of protein localization negative regulation of transcription factor activity
211575_s_at	-0.437	8.102	-2.361	3.198e-02	0.334	-3.722	UBE3A	ubiquitin protein ligase E3A	15	-23133488, -23133488, -23133488	AF116702	7337	15q11-q13	Hs.598862	76	ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms	Ubiquitin mediated proteolysis
211989_at	-0.372	7.094	-2.361	3.199e-02	0.334	-3.722	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	17	-36037505	NM_003079	6605	17q21.2	Hs.696086	31	nuclear chromosome DNA binding chromatin binding transcription coactivator activity nucleus nucleolus nucleosome disassembly regulation of transcription from RNA polymerase II promoter N-acetyltransferase activity SWI/SNF complex chromatin modification transcriptional repressor complex negative regulation of transcription, DNA-dependent protein N-terminus binding
200638_s_at	-0.613	7.537	-2.360	3.201e-02	0.334	-3.723	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	8	-101999980, -101999980, -101999980, -101999980, -101999980	BC003623	7534	8q23.1	Hs.492407 Hs.594673	169	nucleus cytoplasm mitochondrion protein targeting anti-apoptosis signal transduction transcription factor binding protein domain specific binding melanosome	Cell cycle Neurotrophin signaling pathway Pathogenic Escherichia coli infection - EHEC
208679_s_at	-0.394	11.167	-2.360	3.202e-02	0.334	-3.723	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	2	218790118, 218790364	AF279893	10109	2q36.1	Hs.529303	23	actin binding structural constituent of cytoskeleton protein binding cytoplasm Golgi apparatus Arp2/3 protein complex focal adhesion cell motion positive regulation of actin filament polymerization cell leading edge cell projection	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
203535_at	-0.464	4.123	-2.360	3.202e-02	0.334	-3.723	S100A9	S100 calcium binding protein A9	1	151596953	NM_002965	6280	1q21	Hs.112405	102	signal transducer activity calcium ion binding protein binding nucleus nucleolus cytoplasm inflammatory response cell-cell signaling leukocyte chemotaxis actin cytoskeleton reorganization regulation of integrin biosynthetic process
242902_at	0.285	4.511	2.360	3.203e-02	0.334	-3.723	CYMP	chymosin pseudogene	1	110824910	AI479358	643160	1p13.3	Hs.532720	4
203312_x_at	-0.402	6.797	-2.360	3.203e-02	0.334	-3.723	ARF6	ADP-ribosylation factor 6	14	49429485	NM_001663	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
216210_x_at	0.266	7.426	2.360	3.203e-02	0.334	-3.724	TRIOBP	TRIO and F-actin binding protein	22	36422940, 36472186, 36472186	AA046650	11078	22q13.1	Hs.533030	20	actin binding protein binding nucleus cytoplasm actin cytoskeleton GTP-Rho binding actin modification myosin II binding barbed-end actin filament capping
233288_at	0.246	3.420	2.360	3.204e-02	0.334	-3.724	ATR	ataxia telangiectasia and Rad3 related	3	-143650766	AU143947	545	3q22-q24	Hs.271791	186	DNA damage checkpoint nucleotide binding XY body DNA binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm chromosome DNA repair protein amino acid phosphorylation response to DNA damage stimulus cell cycle multicellular organismal development negative regulation of DNA replication transferase activity manganese ion binding MutLalpha complex binding MutSalpha complex binding regulation of protein binding	Cell cycle p53 signaling pathway
238606_at	-0.307	4.550	-2.360	3.206e-02	0.334	-3.724	ZNF747	zinc finger protein 747	16	-30450279	AV698217	65988	16p11.2	Hs.592032	3	nucleic acid binding intracellular regulation of transcription, DNA-dependent
208168_s_at	0.261	3.223	2.360	3.206e-02	0.334	-3.724	CHIT1	chitinase 1 (chitotriosidase)	1	-201451829	NM_003465	1118	1q31-q32	Hs.201688	42	polysaccharide catabolic process chitinase activity extracellular region extracellular space lysosome carbohydrate metabolic process chitin catabolic process immune response chitin binding metabolic process response to bacterium cation binding	Amino sugar and nucleotide sugar metabolism
241866_at	0.646	4.232	2.359	3.208e-02	0.334	-3.725	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	AW975728	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
234485_at	0.347	4.785	2.359	3.208e-02	0.334	-3.725	LOC340947	similar to eukaryotic translation initiation factor 3 subunit 6 interacting protein	10		AL117339	340947	10p11.1	Hs.164084
223320_s_at	-0.476	6.787	-2.359	3.208e-02	0.334	-3.725	ABCB10	ATP-binding cassette, sub-family B (MDR/TAP), member 10	1	-227718951	AF277184	23456	1q42.13	Hs.17614	9	nucleotide binding ATP binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters
221747_at	-0.327	7.501	-2.359	3.209e-02	0.334	-3.725	TNS1	tensin 1	2	-218372756	AL046979	7145	2q35-q36	Hs.471381	16	actin binding protein binding cytoplasm cytoskeleton focal adhesion cell junction
204720_s_at	0.783	3.220	2.359	3.210e-02	0.334	-3.725	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6	1	65503017	AV729634	9829	1pter-q31.3	Hs.647643	11	protein tyrosine phosphatase activity hydrolase activity SH3 domain binding heat shock protein binding	Endocytosis
206946_at	0.300	4.845	2.359	3.211e-02	0.334	-3.726	HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	15	-71399253	NM_005477	10021	15q24-q25	Hs.86941	29	nucleotide binding in utero embryonic development intracellular cAMP activated cation channel activity voltage-gated ion channel activity voltage-gated potassium channel activity sodium channel activity protein binding cation transport potassium ion transport sodium ion transport muscle contraction blood circulation regulation of heart contraction membrane integral to membrane cAMP binding potassium ion binding sodium ion binding
218660_at	-0.288	9.017	-2.359	3.212e-02	0.334	-3.726	DYSF	dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)	2	71534260, 71534260, 71547339	NM_003494	8291	2p13.3-p13.1	Hs.252180	59	plasma membrane muscle contraction integral to membrane cytoplasmic vesicle
205172_x_at	-0.310	8.206	-2.359	3.213e-02	0.334	-3.726	CLTB	clathrin, light chain (Lcb)	5	-175752061	NM_007097	1212	4q2-q3 5q35	Hs.484241	17	structural molecule activity calcium ion binding protein binding intracellular protein transport membrane vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle	Lysosome Endocytosis Huntington's disease
233516_s_at	0.261	4.056	2.358	3.213e-02	0.334	-3.726	SPAG17	sperm associated antigen 17	1	-118297810	AL137581	200162	1p12	Hs.528821	7	protein binding cytoplasm microtubule cilium flagellum flagellar axoneme
204496_at	-0.431	8.897	-2.358	3.216e-02	0.334	-3.727	STRN3	striatin, calmodulin binding protein 3	14	-30432755	NM_014574	29966	14q13-q21	Hs.21016 Hs.401843	13	calmodulin binding membrane fraction nucleus cytoplasm cytosol cell cycle membrane
228263_at	0.337	6.451	2.357	3.220e-02	0.335	-3.728	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	12	50687014	AI190755	160622	12q13.13	Hs.407202	7	protein binding cytoplasm plasma membrane signal transduction cell junction synapse postsynaptic membrane perinuclear region of cytoplasm
1552520_at	0.431	4.739	2.357	3.221e-02	0.335	-3.728	TMEM74	transmembrane protein 74	8	-109864521	BC030710	157753	8q23.1	Hs.99439	4	membrane integral to membrane
211979_at	-0.289	6.652	-2.357	3.221e-02	0.335	-3.728	GPR107	G protein-coupled receptor 107	9	131855805	AB046844	57720	9q34.11	Hs.512461	7	membrane integral to membrane
233720_at	0.288	3.038	2.357	3.222e-02	0.335	-3.728	SORBS2	sorbin and SH3 domain containing 2	4	-186743592, -186743592, -186743592, -186743592, -186743592, -186743591, -186743591	AK000782	8470	4q35.1	Hs.619806 Hs.655143	30	structural constituent of cytoskeleton protein binding nucleus cytoplasm cytoskeletal adaptor activity biological_process structural constituent of muscle actin cytoskeleton Z disc perinuclear region of cytoplasm
1555385_at	-0.395	5.463	-2.357	3.223e-02	0.335	-3.729	B4GALNT1	beta-1,4-N-acetyl-galactosaminyl transferase 1	12	-56305817	BC029828	2583	12q13.3	Hs.591019	11	ganglioside biosynthetic process (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity membrane fraction Golgi apparatus carbohydrate metabolic process glycosphingolipid metabolic process spermatogenesis membrane integral to membrane transferase activity, transferring hexosyl groups lipid storage integral to Golgi membrane lipid glycosylation	Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
222984_at	-0.259	10.826	-2.357	3.223e-02	0.335	-3.729	PAIP2	poly(A) binding protein interacting protein 2	5	138705417, 138706032	AF151052	51247	5q31.2	Hs.396644	16	protein binding cytoplasm regulation of translation translation repressor activity negative regulation of translational initiation
237687_at	-0.684	5.915	-2.356	3.227e-02	0.335	-3.730	LOC283737	hypothetical protein LOC283737	15		H40786	283737	15q25.3	Hs.31795	1
214229_at	0.205	3.405	2.356	3.228e-02	0.335	-3.730	DNAH17	dynein, axonemal, heavy chain 17	17		AL122077	8632	17q25.3	Hs.375975 Hs.713207	7	nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme
204135_at	-0.563	8.536	-2.356	3.229e-02	0.335	-3.731	FILIP1L	filamin A interacting protein 1-like	3	-101049461, -101049461, -101034677	NM_014890	11259	3q12.1	Hs.104672	8	molecular_function nucleus cytoplasm biological_process membrane myosin complex
218307_at	0.327	7.716	2.356	3.230e-02	0.335	-3.731	RSAD1	radical S-adenosyl methionine domain containing 1	17	45911188	NM_018346	55316	17q21.33	Hs.8033	3	coproporphyrinogen oxidase activity iron ion binding cytoplasm mitochondrion porphyrin biosynthetic process oxidoreductase activity metal ion binding 4 iron, 4 sulfur cluster binding oxidation reduction
231260_at	0.347	3.911	2.355	3.233e-02	0.335	-3.731	BC036928	hypothetical protein BC036928	19		AW162207	386758	19q13.43	Hs.549564	1
225922_at	-0.542	7.307	-2.355	3.233e-02	0.335	-3.732	FNIP2	folliculin interacting protein 2	4	159909631	BE501838	57600	4q32.1	Hs.652441 Hs.709500	4	protein binding cytoplasm
232345_at	0.236	4.856	2.355	3.235e-02	0.335	-3.732	C18orf8	chromosome 18 open reading frame 8	18	19337459	AU158529	29919	18q11.2	Hs.464779	4
238792_at	0.334	5.515	2.355	3.235e-02	0.335	-3.732	PCNX	pecanex homolog (Drosophila)	14	70443874	BF209668	22990	14q24.2	Hs.446559	10	membrane integral to membrane
223938_at	0.237	5.726	2.355	3.235e-02	0.335	-3.732	C1orf49	chromosome 1 open reading frame 49	1	176748834	AL136694	84066	1q25.2	Hs.534501	10	microtubule cytoskeleton
232284_at	0.405	4.777	2.355	3.236e-02	0.335	-3.732	PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	3	-63971270	AI206345	9861	3p14.1	Hs.152536	35	proteasome complex protein binding cytosol proteolysis ATPase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
231056_at	0.294	5.900	2.355	3.236e-02	0.335	-3.732	LOC339352	similar to Putative ATP-binding domain-containing protein 3-like protein	19		AI479923	339352	19q13.41
1438_at	0.249	5.106	2.355	3.237e-02	0.335	-3.733	EPHB3	EPH receptor B3	3	185762280	X75208	2049	3q21-qter	Hs.2913	20	nucleotide binding receptor activity ephrin receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway axon guidance receptor activity membrane transferase activity central nervous system projection neuron axonogenesis retinal ganglion cell axon guidance	Axon guidance
202181_at	-0.346	6.970	-2.355	3.238e-02	0.335	-3.733	KIAA0247	KIAA0247	14	69148062	NM_014734	9766	14q24.1	Hs.440025	3	molecular_function cellular_component biological_process membrane integral to membrane
209885_at	0.555	5.857	2.354	3.238e-02	0.335	-3.733	RHOD	ras homolog gene family, member D	11	66580864	BC001338	29984	11q14.3	Hs.15114	22	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction	Axon guidance
208632_at	-0.572	7.818	-2.354	3.239e-02	0.335	-3.733	RNF10	ring finger protein 10	12	119456514	AL578551	9921	12q24.31	Hs.442798	10	protein binding cytoplasm zinc ion binding positive regulation of transcription metal ion binding
244755_at	0.305	4.101	2.354	3.239e-02	0.335	-3.733	XPR1	xenotropic and polytropic retrovirus receptor	1	178867768	AI243681	9213	1q25.1	Hs.227656	6	G-protein coupled receptor activity plasma membrane integral to plasma membrane G-protein coupled receptor protein signaling pathway
220259_at	0.248	3.264	2.354	3.239e-02	0.335	-3.733	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	17	-38073458	NM_024927	79990	17q21.2	Hs.632251	2	cytoskeleton
218442_at	-0.436	7.266	-2.354	3.240e-02	0.335	-3.733	TTC4	tetratricopeptide repeat domain 4	1	54954116	NM_004623	7268	1p32.3	Hs.412482	10	binding
211725_s_at	0.847	4.851	2.354	3.241e-02	0.335	-3.734	BID	BH3 interacting domain death agonist	22	-16596905, -16596905	BC005884	637	22q11.1	Hs.591054	111	release of cytochrome c from mitochondria death receptor binding protein binding membrane fraction cytoplasm mitochondrion mitochondrial outer membrane cytosol cytosol induction of apoptosis via death domain receptors activation of pro-apoptotic gene products membrane regulation of mitochondrial membrane permeability neuron apoptosis	p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer
214364_at	0.285	6.133	2.354	3.242e-02	0.335	-3.734	MTERFD2	MTERF domain containing 2	2	-241683654, -241675182	W84525	130916	2q37.3	Hs.159556	5
227407_at	-0.471	9.295	-2.353	3.247e-02	0.335	-3.735	TAPT1	transmembrane anterior posterior transformation 1	4	-15771225	AI341541	202018	4p15.32	Hs.479223	5	receptor activity multicellular organismal development membrane integral to membrane
222982_x_at	-0.698	10.683	-2.353	3.250e-02	0.335	-3.736	SLC38A2	solute carrier family 38, member 2	12	-45038238	AF298897	54407	12q	Hs.221847	20	plasma membrane ion transport sodium ion transport amino acid transport symporter activity integral to membrane sodium ion binding
238090_at	0.291	3.262	2.353	3.250e-02	0.335	-3.736	HGSNAT	heparan-alpha-glucosaminide N-acetyltransferase	8	43114748	BE327420	138050	8p11.1	Hs.600384	11	lysosome acyltransferase activity heparan-alpha-glucosaminide N-acetyltransferase activity membrane integral to membrane transferase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
203213_at	-0.490	3.318	-2.352	3.252e-02	0.335	-3.737	CDC2	cell division cycle 2, G1 to S and G2 to M	10	62208225, 62208296, 62209904	AL524035	983	10q21.1	Hs.334562	350	nucleotide binding cyclin-dependent protein kinase activity cyclin-dependent protein kinase activity protein binding ATP binding nucleus nucleoplasm cytosol spindle microtubule protein amino acid phosphorylation anti-apoptosis cell cycle mitosis RNA polymerase II carboxy-terminal domain kinase activity transferase activity midbody anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle p53 signaling pathway Gap junction
206718_at	0.474	8.041	2.352	3.253e-02	0.335	-3.737	LMO1	LIM domain only 1 (rhombotin 1)	11	-8202432	NM_002315	4004	11p15	Hs.654426	21	transcription factor activity nucleus multicellular organismal development zinc ion binding cell proliferation metal ion binding
216733_s_at	-1.129	8.037	-2.352	3.253e-02	0.335	-3.737	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	X86401	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
1560715_at	0.338	3.428	2.352	3.254e-02	0.335	-3.737	P4HA3	prolyl 4-hydroxylase, alpha polypeptide III	11	-73655349	AL833965	283208	11q13.4	Hs.660541	4	procollagen-proline 4-dioxygenase activity binding iron ion binding endoplasmic reticulum endoplasmic reticulum lumen oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Arginine and proline metabolism Metabolic pathways
1569472_s_at	-0.652	2.922	-2.352	3.255e-02	0.335	-3.738	TTC3	tetratricopeptide repeat domain 3	21	37367440, 37377116	BC026260	7267	21q22.2	Hs.368214	9	protein binding cellular_component vacuole biological_process zinc ion binding negative regulation of cell morphogenesis involved in differentiation negative regulation of neuron differentiation metal ion binding response to protein stimulus
203475_at	0.215	4.197	2.352	3.255e-02	0.335	-3.738	CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	15	-49287545	NM_000103	1588	15q21.1	Hs.260074	375	membrane fraction endoplasmic reticulum steroid biosynthetic process steroid biosynthetic process electron carrier activity membrane oxygen binding heme binding metal ion binding oxidation reduction aromatase activity	Androgen and estrogen metabolism Metabolic pathways
242855_at	0.307	5.425	2.351	3.258e-02	0.336	-3.738	KCP	kielin/chordin-like protein	7	-128317236, -128304155	AI125516	375616	7q32.1	Hs.371746	2	extracellular region
236183_at	0.289	3.692	2.351	3.258e-02	0.336	-3.738	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	14	101500617	BF511676	1778	14q32 14q32.3-qter	Hs.649497	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm Golgi apparatus cytoplasmic dynein complex microtubule microtubule-based movement mitotic spindle organization ATPase activity, coupled
206899_at	0.319	4.901	2.351	3.261e-02	0.336	-3.739	NTSR2	neurotensin receptor 2	2	-11715754	NM_012344	23620	2p25.1	Hs.131138	14	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger sensory perception neurotensin receptor activity, G-protein coupled regulation of membrane potential	Neuroactive ligand-receptor interaction
208093_s_at	-0.319	7.737	-2.351	3.262e-02	0.336	-3.739	NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	17	8279903	NM_030808	81565	17p13.1	Hs.372123	38	condensed chromosome kinetochore protein binding cytoplasm centrosome spindle cytoskeleton microtubule transport chromosome segregation multicellular organismal development nervous system development cell differentiation
1562953_s_at	0.391	5.118	2.351	3.263e-02	0.336	-3.740	C4orf12	chromosome 4 open reading frame 12	4	86106994	BC019264	404201	4q21.3	Hs.46730	4
225266_at	-0.442	7.794	-2.350	3.265e-02	0.336	-3.740	ZNF652	zinc finger protein 652	17	-44721567, -44721567	AA526904	22834	17q21.32-q21.33	Hs.463375	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
232745_x_at	0.405	4.034	2.350	3.265e-02	0.336	-3.740	SPEF2	sperm flagellar 2	5	35653745, 35653745	AK026817	79925	5p13.2	Hs.298863	10	protein dimerization activity
210639_s_at	-0.362	6.275	-2.350	3.269e-02	0.336	-3.741	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	6	-106739044	AF293841	9474	6q21	Hs.486063	30	autophagic vacuole formation protein binding cytoplasm autophagic vacuole autophagy apoptosis pre-autophagosomal structure membrane post-translational protein modification	Regulation of autophagy RIG-I-like receptor signaling pathway
230388_s_at	-1.724	8.135	-2.349	3.270e-02	0.336	-3.742	LOC644246	hypothetical protein LOC644246	17		AI797017	644246	17q21.31	Hs.644600	1
209404_s_at	-0.379	6.153	-2.349	3.271e-02	0.336	-3.742	TMED7	transmembrane emp24 protein transport domain containing 7	5	-114977101	AF151867	51014	5q22.3	Hs.642817 Hs.710895	7	endoplasmic reticulum transport membrane integral to membrane
227112_at	-0.502	7.923	-2.349	3.275e-02	0.336	-3.743	TMCC1	transmembrane and coiled-coil domain family 1	3	-130849324, -130849324	AW270037	23023	3q22.1	Hs.477547 Hs.709936	6	membrane integral to membrane
223206_s_at	-0.420	4.955	-2.349	3.275e-02	0.336	-3.743	NMRAL1	NmrA-like family domain containing 1	16	-4451695	BC002927	57407	16p13.3	Hs.288969	8	binding regulation of nitrogen utilization oxidoreductase activity transcription repressor activity oxidation reduction
203920_at	0.383	5.158	2.349	3.276e-02	0.336	-3.743	NR1H3	nuclear receptor subfamily 1, group H, member 3	11	47227024, 47236072	NM_005693	10062	11p11.2	Hs.438863 Hs.513522	94	transcription factor activity steroid hormone receptor activity transcription coactivator activity thyroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding positive regulation of specific transcription from RNA polymerase II promoter negative regulation of foam cell differentiation positive regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux negative regulation of cholesterol storage positive regulation of cellular protein metabolic process negative regulation of lipid transport sequence-specific DNA binding positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of pinocytosis positive regulation of lipoprotein lipase activity	PPAR signaling pathway
201906_s_at	0.637	7.024	2.348	3.277e-02	0.336	-3.744	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	NM_005808	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
215631_s_at	-0.267	6.404	-2.348	3.280e-02	0.337	-3.744	BRMS1	breast cancer metastasis suppressor 1	11	-65861379	AL050008	25855	11q13-q13.2	Hs.100426	32	molecular_function protein binding cellular_component biological_process
32128_at	0.329	3.617	2.348	3.281e-02	0.337	-3.744	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	17	31415755	Y13710	6362	17q11.2	Hs.143961	35	extracellular region extracellular space chemotaxis inflammatory response immune response signal transduction cell-cell signaling chemokine activity response to biotic stimulus	Cytokine-cytokine receptor interaction Chemokine signaling pathway
209242_at	0.613	4.967	2.348	3.281e-02	0.337	-3.745	PEG3	paternally expressed 3	19	-62013256, -62013256	AL042588	5178	19q13.4	Hs.719209	18	nucleic acid binding transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent apoptosis zinc ion binding metal ion binding
213547_at	-0.322	10.366	-2.348	3.281e-02	0.337	-3.745	CAND2	cullin-associated and neddylation-dissociated 2 (putative)	3	12813170	AB014567	23066	3p25.2	Hs.343664	7	intracellular nucleus transcription activator activity TATA-binding protein binding modification-dependent protein catabolic process regulation of transcription
1555847_a_at	-0.370	7.568	-2.348	3.282e-02	0.337	-3.745	LOC284454	hypothetical protein LOC284454	19		BU617052	284454	19p13.13	Hs.436426
228830_s_at	-0.596	6.420	-2.347	3.283e-02	0.337	-3.745	ATF7	activating transcription factor 7	12	-52192109, -52192109	AI279868	11016	12q13	Hs.12286	18	transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding protein dimerization activity
1552998_at	0.378	3.086	2.347	3.283e-02	0.337	-3.745	DEFB125	defensin, beta 125	20	16350	NM_153325	245938	20p13	Hs.380220	3	extracellular region defense response to bacterium
223316_at	-0.552	7.140	-2.347	3.284e-02	0.337	-3.745	CCDC3	coiled-coil domain containing 3	10	-12978630	AL136562	83643	10p13	Hs.498720	8	endoplasmic reticulum
227322_s_at	-0.315	8.389	-2.347	3.286e-02	0.337	-3.746	BCCIP	BRCA2 and CDKN1A interacting protein	10	127502093, 127502093, 127502093	BE464077	56647	10q26.1	Hs.370292 Hs.715543	31	regulation of cyclin-dependent protein kinase activity protein binding nucleus DNA repair response to DNA damage stimulus cell cycle
201656_at	0.460	7.315	2.347	3.287e-02	0.337	-3.746	ITGA6	integrin, alpha 6	2	173000559	NM_000210	3655	2q31.1	Hs.133397	114	receptor activity calcium ion binding protein binding cell-substrate junction assembly cell adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Hematopoietic cell lineage Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1552276_a_at	0.334	5.144	2.346	3.292e-02	0.337	-3.748	VPS18	vacuolar protein sorting 18 homolog (S. cerevisiae)	15	38973919	NM_080432	57617	15q14-q15	Hs.23876	11	actin binding protein binding lysosome early endosome actin filament endosome organization lysosome organization zinc ion binding protein transport membrane metal ion binding
204446_s_at	-0.377	3.702	-2.346	3.293e-02	0.337	-3.748	ALOX5	arachidonate 5-lipoxygenase	10	45189634	NM_000698	240	10q11.2	Hs.89499	141	arachidonate 5-lipoxygenase activity iron ion binding calcium ion binding protein binding nucleus nuclear envelope lumen cytoplasm cytosol inflammatory response membrane lipoxygenase activity nuclear matrix oxidoreductase activity leukotriene biosynthetic process nuclear membrane oxidation reduction	Arachidonic acid metabolism Linoleic acid metabolism Metabolic pathways
238454_at	0.657	4.467	2.345	3.296e-02	0.337	-3.749	ZNF540	zinc finger protein 540	19	42734147	AA013398	163255	19q13.12	Hs.121283	5	DNA binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207253_s_at	-0.281	7.180	-2.345	3.298e-02	0.337	-3.749	UBN1	ubinuclein 1	16	4837912, 4842077	NM_016936	29855	16p13.3	Hs.440219	9	transcription factor activity nucleus nucleoplasm tight junction regulation of transcription from RNA polymerase II promoter chromatin modification cell junction interspecies interaction between organisms
231966_at	-0.301	4.126	-2.345	3.298e-02	0.337	-3.749	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A	7	94374884	AB033048	55607	7q21.3	Hs.21816	12	actin binding protein binding cytoplasm cytoskeleton actin filament organization multicellular organismal development nervous system development synaptosome cell junction cell differentiation filopodium cortical actin cytoskeleton dendritic spine synapse
219543_at	-0.550	4.884	-2.345	3.301e-02	0.337	-3.750	PBLD	phenazine biosynthesis-like protein domain containing	10	-69714843, -69712422	NM_022129	64081	10pter-q25.3	Hs.198158	7	cellular_component biological_process biosynthetic process isomerase activity
216458_at	0.237	5.217	2.344	3.304e-02	0.338	-3.751	PQLC3	PQ loop repeat containing 3	2	11212990	AL161956	130814	2p25.1	Hs.274415	5	membrane integral to membrane
227646_at	0.504	6.777	2.344	3.305e-02	0.338	-3.751	EBF1	early B-cell factor 1	5	-158055500	BG435302	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
228166_at	0.400	4.161	2.343	3.309e-02	0.338	-3.752	ALG2	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)	9	-101018527	BE644996	85365	9q22.33	Hs.40919	25	alpha-1,3-mannosyltransferase activity membrane fraction nucleus cytoplasm dolichol-linked oligosaccharide biosynthetic process protein localization biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid glycosylation in endoplasmic reticulum protein anchor protein heterodimerization activity protein N-terminus binding calcium-dependent protein binding calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion	N-Glycan biosynthesis Metabolic pathways
213001_at	-0.609	7.322	-2.343	3.310e-02	0.338	-3.752	ANGPTL2	angiopoietin-like 2	9	-128889448	AF007150	23452	9q34	Hs.653262	11	receptor binding extracellular region extracellular space signal transduction multicellular organismal development
200681_at	-0.458	10.173	-2.343	3.311e-02	0.338	-3.753	GLO1	glyoxalase I	6	-38751679	NM_006708	2739	6p21.3-p21.1	Hs.268849	46	lactoylglutathione lyase activity cytoplasm carbohydrate metabolic process anti-apoptosis anti-apoptosis anti-apoptosis zinc ion binding lyase activity metal ion binding	Pyruvate metabolism
223572_at	-0.413	10.499	-2.343	3.311e-02	0.338	-3.753	HHATL	hedgehog acyltransferase-like	3	-42709159, -42709159	AB042554	57467	3p22.1	Hs.476041	4	protein binding endoplasmic reticulum membrane integral to membrane negative regulation of N-terminal protein palmitoylation
1555819_s_at	0.261	5.026	2.343	3.312e-02	0.338	-3.753	SAMD14	sterile alpha motif domain containing 14	17	-45545033	AY148482	201191	17q21.33	Hs.567769	6
201632_at	-0.270	7.777	-2.343	3.313e-02	0.338	-3.753	EIF2B1	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	12	-122671522	NM_001414	1967	12q24.31	Hs.716475	26	translation initiation factor activity guanyl-nucleotide exchange factor activity protein binding membrane fraction cytoplasm eukaryotic translation initiation factor 2B complex plasma membrane translational initiation response to heat response to heat response to glucose stimulus oligodendrocyte development response to peptide hormone stimulus cellular metabolic process cellular response to stimulus
230280_at	-0.432	2.830	-2.343	3.314e-02	0.338	-3.754	TRIM9	tripartite motif-containing 9	14	-50532534, -50511730	BF057241	114088	14q22.1	Hs.654750	11	protein binding intracellular cytoplasm zinc ion binding protein homodimerization activity metal ion binding
215026_x_at	0.303	7.110	2.342	3.315e-02	0.338	-3.754	SCNN1A	sodium channel, nonvoltage-gated 1 alpha	12	-6326271, -6326271, -6326271	U81961	6337	12p13	Hs.591047	80	actin binding ion channel activity protein binding membrane fraction plasma membrane ion transport sodium ion transport excretion external side of plasma membrane amiloride-sensitive sodium channel activity integral to membrane apical plasma membrane cortical actin cytoskeleton sodium ion binding sodium channel complex WW domain binding response to stimulus sensory perception of taste	Taste transduction
232315_at	-0.752	3.312	-2.342	3.316e-02	0.338	-3.754	LOC400713	zinc finger protein LOC400713	19	57564981	AU149712	400713	19q13.41	Hs.502314	3	nucleic acid binding intracellular regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203632_s_at	-0.302	7.897	-2.342	3.317e-02	0.338	-3.754	GPRC5B	G protein-coupled receptor, family C, group 5, member B	16	-19777793	NM_016235	51704	16p12	Hs.148685	8	receptor activity G-protein coupled receptor activity nucleus plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane cytoplasmic vesicle
219570_at	-0.316	6.529	-2.342	3.317e-02	0.338	-3.754	KIF16B	kinesin family member 16B	20	-16200748	NM_024704	55614	20p11.23	Hs.101774	10	nucleotide binding microtubule motor activity protein binding ATP binding microtubule microtubule-based movement cell communication phosphoinositide binding
1565759_at	-0.300	5.615	-2.342	3.319e-02	0.338	-3.755	RPL13	ribosomal protein L13	16	88154590, 88154631	BG396520	6137	16q24.3 17p11.2	Hs.410817	17	RNA binding structural constituent of ribosome protein binding intracellular cytosol translational elongation cytosolic ribosome	Ribosome
231793_s_at	-0.888	6.074	-2.342	3.320e-02	0.338	-3.755	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	4	-114597792, -114591638	AA448956	817	4q26	Hs.144114	29	G1/S transition of mitotic cell cycle nucleotide binding regulation of cell growth calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm calcium- and calmodulin-dependent protein kinase complex calcium ion transport transferase activity T-tubule protein amino acid autophosphorylation cardiac muscle contraction	ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma
222203_s_at	-0.411	8.368	-2.341	3.321e-02	0.338	-3.755	RDH14	retinol dehydrogenase 14 (all-trans/9-cis/11-cis)	2	-18599469	AK023625	57665	2p24.2	Hs.288880	12	binding endoplasmic reticulum cytosol 5'-nucleotidase activity nucleoside metabolic process oxidoreductase activity oxidation reduction
218967_s_at	0.653	6.965	2.341	3.323e-02	0.338	-3.756	PTER	phosphotriesterase related	10	16518972	NM_030664	9317	10p12	Hs.444321 Hs.716660	6	zinc ion binding catabolic process hydrolase activity, acting on ester bonds metal ion binding
218471_s_at	0.276	6.786	2.341	3.323e-02	0.338	-3.756	BBS1	Bardet-Biedl syndrome 1	11	66034694	NM_024649	582	11q13.1	Hs.502915	22	microtubule cytoskeleton organization retina homeostasis protein binding cytoplasm plasma membrane sensory perception of smell photoreceptor cell morphogenesis flagellum assembly fertilization dendrite development striatum development hippocampus development cerebral cortex development adult behavior motile secondary cilium BBSome sensory cilium assembly multicellular organism growth olfactory behavior hormone metabolic process cellular lipid metabolic process fat cell differentiation photoreceptor cell maintenance brain morphogenesis response to stimulus cilium membrane cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility
1554414_a_at	-0.294	5.777	-2.341	3.324e-02	0.338	-3.756	OSGIN2	oxidative stress induced growth inhibitor family member 2	8	90983268, 90983934	BC031054	734	8q21	Hs.436445 Hs.647149	5	molecular_function cellular_component meiosis germ cell development
204986_s_at	0.321	5.359	2.341	3.325e-02	0.338	-3.756	TAOK2	TAO kinase 2	16	29892722, 29892722	NM_016151	9344	16p11.2	Hs.291623	16	nucleotide binding activation of MAPKK activity magnesium ion binding regulation of cell growth protein serine/threonine kinase activity ATP binding protein targeting to membrane apoptosis response to stress regulation of cell shape membrane integral to membrane cytoplasmic membrane-bounded vesicle cell migration transferase activity actin cytoskeleton organization positive regulation of JNK cascade focal adhesion formation	MAPK signaling pathway
218049_s_at	0.299	8.378	2.341	3.326e-02	0.338	-3.757	MRPL13	mitochondrial ribosomal protein L13	8	-121477263	NM_014078	28998	8q22.1-q22.3	Hs.333823	8	structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation	Ribosome
232643_at	0.258	5.610	2.341	3.328e-02	0.339	-3.757	POLR2F	polymerase (RNA) II (DNA directed) polypeptide F	22	36679619	AK026327	5435	22q13.1	Hs.436578	87	nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm nucleolus transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter RNA polymerase complex	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
239775_at	0.231	3.605	2.340	3.329e-02	0.339	-3.757	LOC100131512	hypothetical LOC100131512	7		AI761504	100131512	7p21.1
227199_at	0.443	6.555	2.340	3.331e-02	0.339	-3.758	DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	21	46703289, 46703289, 46703289, 46703289, 46703289	AW027812	23181	21q22.3	Hs.189585	11	catalytic activity nucleus multicellular organismal development transcription factor binding metabolic process
223449_at	0.416	6.406	2.340	3.333e-02	0.339	-3.758	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	5	-115807149	AF225425	57556	5q23.1	Hs.156967	11	receptor activity protein binding apoptosis cytoskeleton organization cell surface receptor linked signal transduction multicellular organismal development nervous system development axon guidance organ morphogenesis membrane integral to membrane cell differentiation axon	Axon guidance
225810_at	-0.406	7.380	-2.340	3.333e-02	0.339	-3.758	MTMR10	myotubularin related protein 10	15	-29018435	AL572015	54893	15q13.3	Hs.30141 Hs.706035	7	dephosphorylation phosphatase activity
205030_at	-2.000	6.423	-2.340	3.333e-02	0.339	-3.759	FABP7	fatty acid binding protein 7, brain	6	123142344	NM_001446	2173	6q22-q23	Hs.26770	28	transporter activity cytoplasm transport nervous system development negative regulation of cell proliferation lipid binding	PPAR signaling pathway
1557105_a_at	0.331	6.039	2.339	3.338e-02	0.339	-3.760	ZNF397OS	zinc finger protein 397 opposite strand	18	-31086816	AW028277	100101467	18q12.2	Hs.464896	3	transcription factor activity intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208833_s_at	-0.401	9.752	-2.339	3.340e-02	0.339	-3.760	ATXN10	ataxin 10	22	44446350	AF119662	25814	22q13.31	Hs.475125	25	protein binding cytoplasm nervous system development cell death dendrite cell soma perinuclear region of cytoplasm
214622_at	0.308	5.161	2.338	3.344e-02	0.339	-3.761	CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2	6	32114060, 3413239, 3221082	M17252	1589	6p21.3	Hs.654479	185	monooxygenase activity steroid 21-monooxygenase activity steroid binding endoplasmic reticulum microsome C21-steroid hormone biosynthetic process electron carrier activity membrane heme binding metal ion binding oxidation reduction	C21-Steroid hormone metabolism Metabolic pathways
229567_at	0.309	10.800	2.337	3.349e-02	0.340	-3.763	FITM1	fat storage-inducing transmembrane protein 1	14	23670514	AI742370	161247	14q12	Hs.128060	2	endoplasmic reticulum membrane integral to membrane
202538_s_at	-0.426	7.071	-2.337	3.350e-02	0.340	-3.763	CHMP2B	chromatin modifying protein 2B	3	87359102	NM_014043	25978	3p11.2	Hs.476930	36	intracellular cytoplasm endosome cytosol protein transport membrane protein domain specific binding	Endocytosis
228506_at	-0.289	4.818	-2.337	3.351e-02	0.340	-3.763	NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	10	-123706592	AA009947	54780	10q26.13	Hs.258798	8
236418_at	0.336	3.931	2.337	3.352e-02	0.340	-3.763	TTLL10	tubulin tyrosine ligase-like family, member 10	1	1099148, 1104939	AW772075	254173	1p36.33	Hs.454835	4	tubulin-tyrosine ligase activity cytoplasm cytoskeleton microtubule protein modification process ligase activity protein polyglycylation protein-glycine ligase activity
1553359_at	0.339	7.972	2.337	3.353e-02	0.340	-3.764	FBXL18	F-box and leucine-rich repeat protein 18	7	-5481953	NM_024963	80028	7p22.2	Hs.623974 Hs.706587	5	modification-dependent protein catabolic process
213281_at	-0.350	5.517	-2.336	3.354e-02	0.340	-3.764	JUN	jun oncogene	1	-59019050	BE327172	3725	1p32-p31	Hs.714791	443	nuclear chromosome transcription factor activity RNA polymerase II transcription factor activity Rho GTPase activator activity nucleus transcription factor complex cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation transcription factor binding negative regulation of cell proliferation cellular process promoter binding negative regulation of protein amino acid autophosphorylation leading edge cell differentiation response to drug positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter protein dimerization activity regulation of cell cycle SMAD protein signal transduction R-SMAD binding	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma
226825_s_at	-0.517	7.351	-2.336	3.355e-02	0.340	-3.764	TMEM165	transmembrane protein 165	4	55956846	AW665624	55858	4q12	Hs.479766	6	membrane integral to membrane
1559139_at	0.334	4.713	2.336	3.355e-02	0.340	-3.764	NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	1	-869445	BC009786	26155	1p36.33	Hs.405987	23	protein binding nucleus nucleolus
222380_s_at	0.342	6.494	2.336	3.356e-02	0.340	-3.764	PDCD6	programmed cell death 6	5	324735	AI907083	10016	5p15.33	Hs.50823	36	calcium ion binding nucleus endoplasmic reticulum apoptosis induction of apoptosis by extracellular signals membrane calcium-dependent protein binding response to calcium ion
231600_at	0.215	2.078	2.336	3.357e-02	0.340	-3.765	CLEC12B	C-type lectin domain family 12, member B	12	10054497, 10054497	AI657064	387837	12p13.2	Hs.127937	3	receptor activity binding sugar binding plasma membrane integral to membrane
213924_at	-1.006	6.968	-2.336	3.357e-02	0.340	-3.765	MPPE1	metallophosphoesterase 1	18	-11873471	BF476502	65258	18p11.21	Hs.712666	8	membrane integral to membrane hydrolase activity metal ion binding
205385_at	0.264	4.511	2.336	3.359e-02	0.340	-3.765	MDM2	Mdm2 p53 binding protein homolog (mouse)	12	67488237, 67489063	M92424	4193	12q14.3-q15	Hs.484551	555	negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding	Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia
1405_i_at	0.432	3.772	2.336	3.359e-02	0.340	-3.765	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	M21121	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
213229_at	0.420	7.505	2.335	3.361e-02	0.340	-3.766	DICER1	dicer 1, ribonuclease type III	14	-94622317, -94622317	BF590131	23405	14q32.13	Hs.87889	63	nucleotide binding magnesium ion binding angiogenesis double-stranded RNA binding helicase activity endonuclease activity ribonuclease III activity protein binding ATP binding intracellular cytoplasm RNA processing ATP-dependent helicase activity RNA-induced silencing complex hydrolase activity stem cell maintenance manganese ion binding lung development RNA interference, production of siRNA RNA interference, targeting of mRNA for destruction gene silencing by RNA pre-microRNA processing embryonic hindlimb morphogenesis branching morphogenesis of a tube
220951_s_at	0.312	5.419	2.335	3.361e-02	0.340	-3.766	A1CF	APOBEC1 complementation factor	10	-52236330	NM_014576	29974	10q11.23	Hs.499643	22	nucleotide binding double-stranded RNA binding single-stranded RNA binding protein binding nucleus cytoplasm endoplasmic reticulum mRNA processing apolipoprotein B mRNA editing enzyme complex protein stabilization
224720_at	-0.296	6.546	-2.335	3.362e-02	0.340	-3.766	MIB1	mindbomb homolog 1 (Drosophila)	18	17575542	AW243097	57534	18q11.2	Hs.140903 Hs.658808	15	blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding
204735_at	0.446	6.391	2.335	3.362e-02	0.340	-3.766	PDE4A	phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)	19	10392332, 10402520, 10404110, 10424632	NM_006202	5141	19p13.2	Hs.89901	32	3',5'-cyclic-AMP phosphodiesterase activity membrane fraction soluble fraction signal transduction membrane hydrolase activity	Purine metabolism
238248_at	0.351	5.015	2.335	3.362e-02	0.340	-3.766	UMOD	uromodulin	16	-20251873	AI935789	7369	16p12.3	Hs.654425	59	calcium ion binding extracellular region plasma membrane cellular defense response negative regulation of cell proliferation apical plasma membrane extrinsic to membrane anchored to membrane
1569383_s_at	0.273	3.984	2.335	3.362e-02	0.340	-3.766	ZFYVE28	zinc finger, FYVE domain containing 28	4	-2241122	BC032605	57732	4p16.3	Hs.292056	3	protein binding cytoplasm endosome cytosol negative regulation of epidermal growth factor receptor activity zinc ion binding membrane early endosome membrane phosphatidylinositol 3-phosphate binding metal ion binding
221050_s_at	0.480	7.075	2.335	3.363e-02	0.340	-3.766	GTPBP2	GTP binding protein 2	6	-43696195	NM_019096	54676	6p21-p12	Hs.485449	7	nucleotide binding GTPase activity GTP binding
210080_x_at	0.273	4.463	2.335	3.365e-02	0.340	-3.767	CELA3A	chymotrypsin-like elastase family, member 3A	1	22200735	D00306	10136	1p36.12	Hs.654349	7	serine-type endopeptidase activity proteolysis digestion cholesterol metabolic process peptidase activity
207468_s_at	0.280	4.364	2.335	3.366e-02	0.340	-3.767	SFRP5	secreted frizzled-related protein 5	10	-99516497	NM_003015	6425	10q24.1	Hs.279565	14	protein binding extracellular region extracellular space apoptosis establishment or maintenance of cell polarity signal transduction multicellular organismal development visual perception anatomical structure morphogenesis Wnt receptor signaling pathway cell differentiation	Wnt signaling pathway
201197_at	-0.650	7.144	-2.335	3.367e-02	0.340	-3.767	AMD1	adenosylmethionine decarboxylase 1	6	111302679, 111302680	NM_001634	262	6q21-q22	Hs.159118	27	adenosylmethionine decarboxylase activity cellular_component spermine biosynthetic process spermidine biosynthetic process lyase activity	Cysteine and methionine metabolism Arginine and proline metabolism Metabolic pathways
200739_s_at	-0.231	7.331	-2.334	3.370e-02	0.340	-3.768	SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	21	-45049959	BG338532	6612	21q22.3	Hs.474005	40	kinetochore protein binding cytoplasm protein sumoylation modification-dependent protein catabolic process
225384_at	-0.524	5.390	-2.334	3.372e-02	0.340	-3.769	DOCK7	dedicator of cytokinesis 7	1	-62692984	BF001267	85440	1p31.3	Hs.406156	15	microtubule cytoskeleton organization guanyl-nucleotide exchange factor activity GTP binding multicellular organismal development nervous system development axonogenesis cell differentiation axon growth cone neuron projection development activation of Rac GTPase activity positive regulation of peptidyl-serine phosphorylation basal part of cell establishment of neuroblast polarity Rac GTPase binding GTPase binding
213503_x_at	-0.650	9.477	-2.334	3.374e-02	0.340	-3.769	ANXA2	annexin A2	15	-58426642, -58426641	BE908217	302	15q21-q22	Hs.511605	137	skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm
224302_s_at	0.373	9.562	2.333	3.375e-02	0.340	-3.769	MRPS36	mitochondrial ribosomal protein S36	5	68549328, 8323	AF271777	92259	5q13.2	Hs.631971	4	structural constituent of ribosome mitochondrion mitochondrial small ribosomal subunit ribosome translation
243815_at	-0.245	3.543	-2.333	3.376e-02	0.340	-3.770	PGBD4	piggyBac transposable element derived 4	15	32181565	AI336987	161779	15q14	Hs.156317	3
217718_s_at	-0.414	10.082	-2.333	3.377e-02	0.340	-3.770	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	20	42947757	NM_014052	7529	20q13.1	Hs.643544	109	cytoplasm cytosol protein targeting Ras protein signal transduction activation of pro-apoptotic gene products enzyme binding protein domain specific binding negative regulation of protein amino acid dephosphorylation melanosome positive regulation of catalytic activity perinuclear region of cytoplasm	Cell cycle Neurotrophin signaling pathway
212008_at	-0.873	6.229	-2.333	3.378e-02	0.340	-3.770	UBXN4	UBX domain protein 4	2	136215658	N29889	23190	2q21.3	Hs.591242	12	protein binding nucleus nuclear envelope endoplasmic reticulum response to unfolded protein membrane integral to membrane
225546_at	-0.652	7.510	-2.333	3.378e-02	0.340	-3.770	EEF2K	eukaryotic elongation factor-2 kinase	16	22125092	W68180	29904	16p12.2	Hs.498892	22	nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP binding cytoplasm cytosol translational elongation protein amino acid phosphorylation translation factor activity, nucleic acid binding transferase activity
240363_at	0.799	8.493	2.333	3.380e-02	0.340	-3.771	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	AW044553	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
212352_s_at	-0.365	10.051	-2.332	3.381e-02	0.340	-3.771	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	14	-74667923	BE780075	10972	14q24.3	Hs.74137	22	protein binding microsome ER-Golgi intermediate compartment Golgi apparatus cis-Golgi network protein transport membrane integral to membrane vesicle-mediated transport melanosome zymogen granule membrane regulated secretory pathway vesicle targeting, to, from or within Golgi
1570352_at	-0.290	2.276	-2.332	3.382e-02	0.340	-3.771	ATM	ataxia telangiectasia mutated	11	107598768, 107663328	BG623786	472	11q22-q23	Hs.367437	504	nucleotide binding DNA binding protein serine/threonine kinase activity ATP binding nucleus nucleoplasm DNA repair response to DNA damage stimulus cell cycle mitotic cell cycle spindle assembly checkpoint reciprocal meiotic recombination signal transduction cell death response to ionizing radiation 1-phosphatidylinositol-3-kinase activity transferase activity cytoplasmic vesicle protein N-terminus binding	Cell cycle p53 signaling pathway Apoptosis
204024_at	-0.231	4.762	-2.332	3.383e-02	0.340	-3.771	OSGIN2	oxidative stress induced growth inhibitor family member 2	8	90983268, 90983934	NM_004337	734	8q21	Hs.436445 Hs.647149	5	molecular_function cellular_component meiosis germ cell development
213225_at	-0.502	9.042	-2.332	3.383e-02	0.340	-3.772	PPM1B	protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform	2	44249503, 44249503, 44249503	AJ271832	5495	2p21	Hs.416769	17	magnesium ion binding protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity manganese ion binding	MAPK signaling pathway
221473_x_at	-0.573	7.589	-2.332	3.384e-02	0.340	-3.772	SERINC3	serine incorporator 3	20	-42561314, -42558277	U49188	10955	20q13.1-q13.3	Hs.272168 Hs.696043	10	protein binding Golgi apparatus plasma membrane induction of apoptosis integral to membrane
212493_s_at	-0.348	7.673	-2.332	3.385e-02	0.340	-3.772	SETD2	SET domain containing 2	3	-47032903	AI761110	29072	3p21.31	Hs.517941	18	DNA binding protein binding nucleus methyltransferase activity oxidoreductase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription transition metal ion binding	Lysine degradation
203737_s_at	-0.347	5.772	-2.332	3.385e-02	0.340	-3.772	PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	10	103882776	NM_015062	23082	10q24.32	Hs.533551	18	nucleotide binding RNA binding nucleus regulation of transcription
1561537_at	0.279	5.817	2.331	3.390e-02	0.341	-3.773	LOC388906	hypothetical protein LOC388906	22		BC039496	388906	22q13.2	Hs.679422	1
205292_s_at	-0.312	10.479	-2.331	3.390e-02	0.341	-3.773	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	7	-26196080	NM_002137	3181	7p15	Hs.487774	54	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm RNA splicing heterogeneous nuclear ribonucleoprotein complex single-stranded telomeric DNA binding RNA transport
222505_at	-0.283	5.369	-2.331	3.392e-02	0.341	-3.774	LMBR1	limb region 1 homolog (mouse)	7	-156166330	BF510801	64327	7q36	Hs.209989	24	receptor activity membrane integral to membrane
1569171_a_at	0.262	4.857	2.331	3.392e-02	0.341	-3.774	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	BC034416	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
1559746_a_at	0.325	4.826	2.331	3.393e-02	0.341	-3.774	ZNF718	zinc finger protein 718	4	43276	AK096662	255403	4p16.3	Hs.428579 Hs.636638	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
215676_at	0.273	5.614	2.330	3.396e-02	0.341	-3.775	BRF1	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)	14	-104746669, -104746667	N91109	2972	14q	Hs.424484	27	transcription factor TFIIIB complex transcription factor activity RNA polymerase III transcription factor activity translation initiation factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription initiation from RNA polymerase III promoter translational initiation zinc ion binding rRNA transcription tRNA transcription transcription activator activity positive regulation of transcription metal ion binding
208654_s_at	-0.686	7.348	-2.330	3.397e-02	0.341	-3.775	CD164	CD164 molecule, sialomucin	6	-109794411	BF669455	8763	6q21	Hs.520313 Hs.644693	17	extracellular region plasma membrane integral to plasma membrane immune response cell adhesion heterophilic cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation	Lysosome
201652_at	-0.242	9.954	-2.329	3.400e-02	0.341	-3.776	COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	8	-68117868	NM_006837	10987	8q13.1	Hs.491912	79	protein deneddylation transcription coactivator activity translation initiation factor activity protein binding nucleus nucleolus cytoplasm eukaryotic translation initiation factor 3 complex transcription from RNA polymerase II promoter translation signalosome peptidase activity metallopeptidase activity metal ion binding regulation of cell cycle
210810_s_at	0.219	4.720	2.329	3.400e-02	0.341	-3.776	SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	11	20577521	AF142501	9152	11p15.2-p15.1	Hs.136557	18	neurotransmitter:sodium symporter activity integral to plasma membrane neurotransmitter transport synaptic transmission symporter activity glycine:sodium symporter activity membrane
233339_s_at	0.247	4.975	2.329	3.403e-02	0.341	-3.777	ARID1B	AT rich interactive domain 1B (SWI1-like)	6	157140777	AW024272	57492	6q25.1	Hs.291587 Hs.714899	22	DNA binding DNA binding transcription coactivator activity protein binding intracellular nucleus nucleolus cytoplasm SWI/SNF complex chromatin modification regulation of transcription chromatin-mediated maintenance of transcription
204993_at	0.307	5.385	2.329	3.405e-02	0.341	-3.777	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	22	21742668	NM_002073	2781	22q11.22	Hs.584760	30	nucleotide binding GTPase activity receptor signaling protein activity GTP binding nuclear envelope cytoplasm endoplasmic reticulum plasma membrane signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding	Long-term depression
204730_at	0.256	4.462	2.329	3.406e-02	0.341	-3.778	RIMS3	regulating synaptic membrane exocytosis 3	1	-40858938	NM_014747	9783	1pter-p22.2	Hs.654808	9	neurotransmitter transport exocytosis cell junction synapse
215894_at	0.304	2.872	2.328	3.407e-02	0.341	-3.778	PTGDR	prostaglandin D2 receptor (DP)	14	51804180	AI460323	5729	14q22.1	Hs.306831	36	prostaglandin J receptor activity receptor activity G-protein coupled receptor activity prostaglandin D receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane male sex determination	Neuroactive ligand-receptor interaction
211171_s_at	0.258	3.677	2.328	3.407e-02	0.341	-3.778	PDE10A	phosphodiesterase 10A	6	-165660767	AB026816	10846	6q26	Hs.348762	13	nucleotide binding magnesium ion binding cytoplasm signal transduction zinc ion binding hydrolase activity cAMP binding cGMP binding 3',5'-cyclic-GMP phosphodiesterase activity	Purine metabolism
222220_s_at	0.261	5.340	2.328	3.412e-02	0.342	-3.779	TSNAXIP1	translin-associated factor X interacting protein 1	16	66398510	AK027245	55815	16q22.1	Hs.632212	3	cytoplasm multicellular organismal development spermatogenesis cell differentiation perinuclear region of cytoplasm
223070_at	-0.465	10.146	-2.327	3.414e-02	0.342	-3.780	SELK	selenoprotein K	3	-53894265	AF085359	58515	3p21.31	Hs.58471 Hs.640242	7	endoplasmic reticulum response to oxidative stress selenium binding
231892_at	0.354	2.917	2.327	3.414e-02	0.342	-3.780	C9orf100	chromosome 9 open reading frame 100	9	-35649340	AA678492	84904	9p13.3	Hs.534579	5	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
217668_at	0.280	4.844	2.327	3.416e-02	0.342	-3.780	C22orf36	chromosome 22 open reading frame 36	22	-23311590	BF511164	388886	22q11.23	Hs.113314	4
223183_at	-0.361	6.888	-2.327	3.418e-02	0.342	-3.781	AGPAT3	1-acylglycerol-3-phosphate O-acyltransferase 3	21	44109543, 44169706	AI928403	56894	21q22.3	Hs.248785	9	1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum cytosol plasma membrane metabolic process acyltransferase activity phospholipid biosynthetic process integral to membrane transferase activity phospholipid:diacylglycerol acyltransferase activity	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways
230943_at	0.487	3.688	2.326	3.422e-02	0.342	-3.782	SOX17	SRY (sex determining region Y)-box 17	8	55533047	AI821669	64321	8q11.23	Hs.98367	15	angiogenesis vasculogenesis DNA binding nucleus beta-catenin binding transcription factor binding negative regulation of Wnt receptor signaling pathway protein destabilization regulation of transcription protein stabilization	Wnt signaling pathway
229711_s_at	-0.407	8.176	-2.326	3.422e-02	0.342	-3.782	MDM2	Mdm2 p53 binding protein homolog (mouse)	12	67488237, 67489063	AA902480	4193	12q14.3-q15	Hs.484551	555	negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding	Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia
220204_s_at	0.222	3.693	2.326	3.424e-02	0.342	-3.782	BMP8A	bone morphogenetic protein 8a	1	39729904	NM_024732	353500	1p34.3	Hs.472497	3	ossification cytokine activity extracellular region extracellular space multicellular organismal development growth factor activity cell differentiation growth cartilage development	Hedgehog signaling pathway TGF-beta signaling pathway
211932_at	-0.450	6.296	-2.325	3.427e-02	0.342	-3.783	HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	2	177785667	BF195526	220988	2q31.2	Hs.516539	13	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex nucleolus cytoplasm RNA splicing
205388_at	-0.741	13.323	-2.325	3.430e-02	0.343	-3.784	TNNC2	troponin C type 2 (fast)	20	-43885261	NM_003279	7125	20q12-q13.11	Hs.182421	12	skeletal muscle contraction actin binding calcium ion binding troponin complex regulation of muscle contraction	Calcium signaling pathway
240161_s_at	-0.359	3.157	-2.324	3.436e-02	0.343	-3.785	CDC20B	cell division cycle 20 homolog B (S. cerevisiae)	5	-54444579	AI470220	166979	5q11.2	Hs.669184	3
1554641_a_at	0.236	5.324	2.324	3.438e-02	0.343	-3.786	TET3	tet oncogene family member 3	2	74126957	BC022243	200424	2p13.1	Hs.516107	6	iron ion binding oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors metal ion binding oxidation reduction
206632_s_at	-0.269	2.185	-2.323	3.440e-02	0.343	-3.786	APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B	22	37708350	NM_004900	9582	22q13.1-q13.2	Hs.226307	18	RNA binding cellular_component biological_process zinc ion binding hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines metal ion binding	Atrazine degradation
228804_at	0.289	6.021	2.323	3.441e-02	0.343	-3.786	DGCR5	DiGeorge syndrome critical region gene 5 (non-protein coding)	22	17338026	AB051434	26220	22q11	Hs.646438	2
203356_at	-0.575	6.737	-2.323	3.441e-02	0.343	-3.786	CAPN7	calpain 7	3	15222736	BE349584	23473	3p24	Hs.631920	6	calcium-dependent cysteine-type endopeptidase activity intracellular nucleus proteolysis peptidase activity cysteine-type peptidase activity
227268_at	-0.723	6.024	-2.323	3.444e-02	0.343	-3.787	RNFT1	ring finger protein, transmembrane 1	17	-55384504	N51514	51136	17q23.1	Hs.531701	1	protein binding zinc ion binding membrane integral to membrane metal ion binding
201873_s_at	-0.399	6.770	-2.323	3.445e-02	0.343	-3.787	ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	4	146238605	NM_002940	6059	4q31	Hs.12013	20	nucleotide binding ATP binding cytoplasm mitochondrion RNA catabolic process ribonuclease inhibitor activity electron carrier activity response to virus ATPase activity interspecies interaction between organisms iron-sulfur cluster binding
224881_at	-0.426	7.082	-2.323	3.445e-02	0.343	-3.788	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1	7	64975691	AV724827	154807	7q11.21	Hs.427232	5	membrane integral to membrane
202932_at	-0.368	6.198	-2.323	3.445e-02	0.343	-3.788	YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	18	-711591	NM_005433	7525	18p11.31-p11.21	Hs.194148	69	nucleotide binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding membrane fraction cytoplasm cytosol protein modification process glucose transport transferase activity protein amino acid autophosphorylation	Adherens junction Tight junction
219094_at	-0.375	3.116	-2.323	3.446e-02	0.343	-3.788	ARMC8	armadillo repeat containing 8	3	139388837, 139388837	NM_014154	25852	3q22.3	Hs.719108	4	binding
1569322_at	0.266	3.920	2.322	3.447e-02	0.343	-3.788	LOC439990	hypothetical gene supported by BC009626; BC048265	10		BC009626	439990	10q22.3	Hs.365566	1
1552678_a_at	-0.618	6.183	-2.322	3.450e-02	0.344	-3.789	USP28	ubiquitin specific peptidase 28	11	-113173806	NM_020886	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
203614_at	-0.296	7.574	-2.322	3.450e-02	0.344	-3.789	UTP14C	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)	13	51496827	NM_021645	9724	13q14.2	Hs.512963	7	nucleus nucleolus rRNA processing meiosis multicellular organismal development spermatogenesis cell differentiation small-subunit processome
241382_at	0.260	3.681	2.322	3.451e-02	0.344	-3.789	PCP4L1	Purkinje cell protein 4 like 1	1	159495140	W22165	654790	1q23.3	Hs.433150	6
1556017_at	0.296	5.856	2.322	3.452e-02	0.344	-3.789	NBEAL2	neurobeachin-like 2	3	46996176	AK092871	23218	3p21.31	Hs.437043	5	binding
204601_at	-0.404	5.473	-2.322	3.452e-02	0.344	-3.789	N4BP1	NEDD4 binding protein 1	16	-47130137	NM_014664	9683	16q12.1	Hs.511839	6	nucleus
233467_s_at	0.296	5.526	2.321	3.453e-02	0.344	-3.790	TSPAN32	tetraspanin 32	11	2279818	AF176071	10077	11p15.5	Hs.271954	9	molecular_function cell-cell signaling membrane integral to membrane
203664_s_at	-0.404	5.923	-2.321	3.455e-02	0.344	-3.790	POLR2D	polymerase (RNA) II (DNA directed) polypeptide D	2	-128320310	NM_004805	5433	2q21	Hs.554831	80	nucleotide binding nuclear mRNA splicing, via spliceosome catalytic activity DNA-directed RNA polymerase activity nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter cellular metabolic process	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
221019_s_at	0.505	6.313	2.321	3.455e-02	0.344	-3.790	COLEC12	collectin sub-family member 12	18	-309355	NM_030781	81035	18pter-p11.3	Hs.464422	8	scavenger receptor activity binding calcium ion binding sugar binding galactose binding phagocytosis, recognition pattern recognition receptor activity carbohydrate mediated signaling membrane integral to membrane low-density lipoprotein binding innate immune response protein homooligomerization
240172_at	-0.591	5.537	-2.321	3.457e-02	0.344	-3.791	ERGIC2	ERGIC and golgi 2	12	-29384845	AA102332	51290	12p11.22	Hs.339453	11	nucleus cytoplasm endoplasmic reticulum Golgi apparatus membrane integral to membrane vesicle-mediated transport
231943_at	0.288	4.601	2.321	3.459e-02	0.344	-3.791	ZFP28	zinc finger protein 28 homolog (mouse)	19	61742128	AA831323	140612		Hs.14794	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1568830_at	0.218	3.668	2.320	3.461e-02	0.344	-3.792	IRAK3	interleukin-1 receptor-associated kinase 3	12	64869244	BC029493	11213	12q14.3	Hs.369265	27	nucleotide binding magnesium ion binding negative regulation of cytokine-mediated signaling pathway MyD88-dependent toll-like receptor signaling pathway protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction response to virus positive regulation of macrophage tolerance induction negative regulation of macrophage cytokine production transferase activity negative regulation of NF-kappaB transcription factor activity response to peptidoglycan response to lipopolysaccharide negative regulation of interleukin-12 production negative regulation of interleukin-12 production negative regulation of interleukin-6 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of toll-like receptor signaling pathway negative regulation of protein catabolic process protein homodimerization activity negative regulation of protein complex disassembly response to exogenous dsRNA negative regulation of MAP kinase activity negative regulation of innate immune response protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway response to interleukin-1	Apoptosis Neurotrophin signaling pathway
204508_s_at	-0.267	3.892	-2.320	3.461e-02	0.344	-3.792	CA12	carbonic anhydrase XII	15	-61402782	BC001012	771	15q22	Hs.210995	27	carbonate dehydratase activity cytoplasm plasma membrane one-carbon metabolic process zinc ion binding integral to membrane lyase activity metal ion binding	Nitrogen metabolism
222834_s_at	-0.560	5.748	-2.320	3.462e-02	0.344	-3.792	GNG12	guanine nucleotide binding protein (G protein), gamma 12	1	-67939736	N32508	55970	1p31.3	Hs.431101	17	signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway hormone-mediated signaling	MAPK signaling pathway Chemokine signaling pathway Regulation of actin cytoskeleton
205746_s_at	-0.324	4.163	-2.320	3.464e-02	0.344	-3.792	ADAM17	ADAM metallopeptidase domain 17	2	-9546861	U86755	6868	2p25	Hs.404914	121	response to hypoxia positive regulation of protein amino acid phosphorylation neutrophil mediated immunity germinal center formation metalloendopeptidase activity interleukin-6 receptor binding integrin binding protein binding cytoplasm integral to plasma membrane cell-cell junction focal adhesion proteolysis epidermal growth factor receptor signaling pathway Notch signaling pathway peptidase activity zinc ion binding positive regulation of cell proliferation response to bacterium cell surface positive regulation of T cell chemotaxis actin cytoskeleton membrane apical plasma membrane SH3 domain binding PDZ domain binding B cell differentiation positive regulation of cell growth positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of cyclin-dependent protein kinase activity during G1/S response to lipopolysaccharide ruffle membrane negative regulation of interleukin-8 production positive regulation of chemokine production regulation of mast cell apoptosis T cell differentiation in the thymus cell adhesion mediated by integrin wound healing, spreading of epidermal cells response to drug membrane raft positive regulation of epidermal growth factor receptor activity metal ion binding spleen development cell motility PMA-inducible membrane protein ectodomain proteolysis response to high density lipoprotein stimulus	Notch signaling pathway Alzheimer's disease Epithelial cell signaling in Helicobacter pylori infection
203896_s_at	0.487	5.565	2.320	3.465e-02	0.344	-3.793	PLCB4	phospholipase C, beta 4	20	9024931	NM_000933	5332	20p12	Hs.472101	17	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding intracellular signaling cascade lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
205785_at	0.327	5.456	2.320	3.465e-02	0.344	-3.793	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	16	31178788, 31178788	J03925	3684	16p11.2	Hs.172631	145	magnesium ion binding glycoprotein binding receptor activity calcium ion binding cell adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane protein heterodimerization activity	Cell adhesion molecules (CAMs) Hematopoietic cell lineage Leukocyte transendothelial migration Regulation of actin cytoskeleton
238711_s_at	-0.346	5.963	-2.320	3.465e-02	0.344	-3.793	ZNF148	zinc finger protein 148	3	-126427202	AI669304	7707	3q21	Hs.592591	34	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex nucleolus Golgi apparatus cellular defense response gamete generation zinc ion binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
203380_x_at	-0.292	8.103	-2.320	3.465e-02	0.344	-3.793	SFRS5	splicing factor, arginine/serine-rich 5	14	69303581, 69303586	NM_006925	6430	14q24	Hs.632326	28	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA splice site selection RNA splicing RS domain binding
203099_s_at	-0.256	5.865	-2.319	3.468e-02	0.344	-3.793	CDYL	chromodomain protein, Y-like	6	4651391, 4721678, 4781330, 4835224	AF081258	9425	6p25.1	Hs.269092	8	chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription
222338_x_at	0.256	6.879	2.319	3.472e-02	0.344	-3.794	LOC646808	similar to L antigen family, member 3	9		AI375965	646808	9p21.1
1569110_x_at	-0.942	8.455	-2.319	3.473e-02	0.344	-3.795	LOC728613	programmed cell death 6 pseudogene	5	-1650671	BC020552	728613	5p15.33	Hs.379186	2
216750_at	0.299	4.585	2.319	3.473e-02	0.344	-3.795	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	4	-40506801	AK024871	323	4p14-p13	Hs.479602	12	beta-amyloid binding nucleus cell cycle arrest intracellular signaling cascade transcription factor binding membrane lamellipodium negative regulation of cell growth growth cone synapse regulation of transcription negative regulation of S phase of mitotic cell cycle
201372_s_at	-0.881	5.309	-2.319	3.473e-02	0.344	-3.795	CUL3	cullin 3	2	-225043112	NM_003590	8452	2q36.2	Hs.372286	39	G1/S transition of mitotic cell cycle protein binding nucleus Golgi apparatus ubiquitin-dependent protein catabolic process cell cycle arrest cyclin catabolic process positive regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
201098_at	-0.361	7.137	-2.318	3.474e-02	0.344	-3.795	COPB2	coatomer protein complex, subunit beta 2 (beta prime)	3	-140559122	NM_004766	9276	3q23	Hs.719115	25	structural molecule activity protein binding cytoplasm Golgi apparatus cytosol intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat cytoplasmic vesicle COPI coating of Golgi vesicle
224308_s_at	-0.434	5.114	-2.318	3.476e-02	0.344	-3.795	INTS2	integrator complex subunit 2	17	-57297511	AL136800	57508	17q23.2	Hs.279646	7	protein binding intracellular nucleus membrane integral to membrane snRNA processing integrator complex
227990_at	-0.559	7.637	-2.318	3.478e-02	0.344	-3.796	SLU7	SLU7 splicing factor homolog (S. cerevisiae)	5	-159761225	AA843238	10569	5q33.3	Hs.435342	9	alternative nuclear mRNA splicing, via spliceosome second spliceosomal transesterification activity nuclear mRNA 3'-splice site recognition nucleic acid binding nucleus spliceosomal complex cytoplasm mRNA processing zinc ion binding RNA splicing nuclear speck small nuclear ribonucleoprotein complex pre-mRNA 3'-splice site binding metal ion binding
228425_at	0.574	4.928	2.318	3.478e-02	0.344	-3.796	LOC654433	hypothetical LOC654433	2	113710316	BF056746	654433	2q13	Hs.656660	4
215508_at	0.260	2.568	2.318	3.478e-02	0.344	-3.796	BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	2	-111111882	AL137654	699	2q14	Hs.469649	55	nucleotide binding condensed chromosome kinetochore condensed nuclear chromosome, centromeric region protein serine/threonine kinase activity ATP binding nucleus spindle pole body protein amino acid phosphorylation cell cycle mitosis mitotic cell cycle spindle assembly checkpoint cell proliferation transferase activity cell division	Cell cycle
219660_s_at	0.392	3.738	2.318	3.479e-02	0.344	-3.796	ATP8A2	ATPase, aminophospholipid transporter-like, class I, type 8A, member 2	13	24844208	NM_016529	51761	13q12	Hs.444957	4	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process negative regulation of cell proliferation ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
205325_at	0.268	4.989	2.318	3.479e-02	0.344	-3.796	PHYHIP	phytanoyl-CoA 2-hydroxylase interacting protein	8	-22133160	NM_014759	9796	8p21.3	Hs.334688	8	protein binding
210768_x_at	-0.241	6.490	-2.318	3.480e-02	0.344	-3.796	TMCO1	transmembrane and coiled-coil domains 1	1	-163960151	AF274935	54499	1q22-q25	Hs.31498 Hs.715707	12	endoplasmic reticulum Golgi apparatus membrane integral to membrane
221774_x_at	-0.243	5.992	-2.318	3.480e-02	0.344	-3.796	FAM48A	family with sequence similarity 48, member A	13	-36481450	AW003334	55578	13q13.3	Hs.435815	14	protein binding multicellular organismal development gastrulation
209647_s_at	-0.435	6.006	-2.317	3.480e-02	0.344	-3.796	SOCS5	suppressor of cytokine signaling 5	2	46779602, 46779852	AW664421	9655	2p21	Hs.468426	14	epidermal growth factor receptor binding protein binding epidermal growth factor receptor signaling pathway intracellular signaling cascade negative regulation of signal transduction cell growth cytokine-mediated signaling pathway modification-dependent protein catabolic process regulation of growth positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation	Jak-STAT signaling pathway
231718_at	-0.446	7.081	-2.317	3.483e-02	0.344	-3.797	SLU7	SLU7 splicing factor homolog (S. cerevisiae)	5	-159761225	NM_006425	10569	5q33.3	Hs.435342	9	alternative nuclear mRNA splicing, via spliceosome second spliceosomal transesterification activity nuclear mRNA 3'-splice site recognition nucleic acid binding nucleus spliceosomal complex cytoplasm mRNA processing zinc ion binding RNA splicing nuclear speck small nuclear ribonucleoprotein complex pre-mRNA 3'-splice site binding metal ion binding
201121_s_at	0.374	7.839	2.317	3.484e-02	0.344	-3.797	PGRMC1	progesterone receptor membrane component 1	X	118254238	NM_006667	10857	Xq22-q24	Hs.90061	26	receptor activity steroid binding protein binding nucleus nucleolus endoplasmic reticulum microsome cell surface membrane integral to membrane heme binding
1554192_s_at	0.237	6.756	2.316	3.487e-02	0.345	-3.798	C4orf23	chromosome 4 open reading frame 23	4	8507042	BC035655	152992	4p16.1	Hs.566191	5	cytoplasm tRNA processing methyltransferase activity transferase activity
1556259_at	0.202	3.943	2.316	3.489e-02	0.345	-3.799	CADM1	cell adhesion molecule 1	11	-114549554	T51129	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
214792_x_at	0.397	5.584	2.316	3.491e-02	0.345	-3.799	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	17	-8003189	AI955119	6844	17p13.1	Hs.25348	66	protein binding integral to plasma membrane membrane vesicle-mediated transport synaptosome cell junction cytoplasmic vesicle synapse	SNARE interactions in vesicular transport
218890_x_at	0.719	8.628	2.316	3.491e-02	0.345	-3.799	MRPL35	mitochondrial ribosomal protein L35	2	86280066	NM_016622	51318	2p11.2	Hs.433439	8	structural constituent of ribosome mitochondrion mitochondrial ribosome ribosome translation translation regulator activity
201434_at	-0.288	8.388	-2.316	3.493e-02	0.345	-3.800	TTC1	tetratricopeptide repeat domain 1	5	159368757	NM_003314	7265	5q33.3	Hs.519718	10	protein folding unfolded protein binding
214417_s_at	0.248	3.783	2.315	3.495e-02	0.345	-3.800	FETUB	fetuin B	3	187840842	N39010	26998	3q27	Hs.81073	10	molecular_function cysteine-type endopeptidase inhibitor activity extracellular region biological_process
223160_s_at	-0.312	6.532	-2.315	3.496e-02	0.345	-3.800	SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	14	-90993708	AK024297	55671	14q32.12	Hs.533887	9	protein binding nucleus cytoplasm centrosome
212977_at	0.670	8.033	2.315	3.496e-02	0.345	-3.800	CXCR7	chemokine (C-X-C motif) receptor 7	2	237143118	AI817041	57007	2q37.3	Hs.471751	21	receptor activity G-protein coupled receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane interspecies interaction between organisms
213387_at	-0.387	5.481	-2.315	3.498e-02	0.345	-3.801	ATAD2B	ATPase family, AAA domain containing 2B	2	-23825037	AB033066	54454	2p24.1-p23.3	Hs.467862	5	nucleotide binding ATP binding nucleoside-triphosphatase activity
223698_at	-0.501	4.371	-2.315	3.498e-02	0.345	-3.801	SLC25A36	solute carrier family 25, member 36	3	142143351	AL136803	55186	3q23	Hs.144130	7	transporter activity binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane response to estradiol stimulus
219050_s_at	-0.267	5.120	-2.315	3.498e-02	0.345	-3.801	ZNHIT2	zinc finger, HIT type 2	11	-64640450	NM_014205	741	11q13	Hs.121025	7	zinc ion binding metal ion binding
220188_at	0.273	3.516	2.315	3.498e-02	0.345	-3.801	JPH3	junctophilin 3	16	86193999	NM_020655	57338	16q24.3	Hs.592068	18	molecular_function protein binding endoplasmic reticulum plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
225492_at	-0.502	7.533	-2.314	3.501e-02	0.345	-3.802	TMEM33	transmembrane protein 33	4	41631893	BG500396	55161	4p13	Hs.31082	5	protein binding biological_process membrane integral to membrane melanosome
215355_at	0.275	2.647	2.314	3.501e-02	0.345	-3.802	POU2F3	POU class 2 homeobox 3	11	119616160	AI686582	25833	11q23.3	Hs.227115	13	transcription factor activity nucleus transcription factor complex epidermis development keratinocyte differentiation wound healing sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein dimerization activity
213462_at	0.376	5.750	2.314	3.503e-02	0.345	-3.802	NPAS2	neuronal PAS domain protein 2	2	100803044	AW000928	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
223610_at	0.279	5.881	2.314	3.503e-02	0.345	-3.802	SEMA5B	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	3	-124110732	BC002776	54437	3q21.1	Hs.210870	6	receptor activity multicellular organismal development nervous system development membrane integral to membrane cell differentiation	Axon guidance
235397_at	0.360	5.991	2.314	3.506e-02	0.345	-3.803	NCRNA00174	non-protein coding RNA 174	7	-65478466	AA020789	285908	7q11.21	Hs.50755	3
1556601_a_at	0.253	4.468	2.314	3.507e-02	0.345	-3.803	SPATA13	spermatogenesis associated 13	13	23632886	R69077	221178	13q12.12	Hs.657121	7	Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
210443_x_at	0.229	6.416	2.313	3.509e-02	0.345	-3.804	OGFR	opioid growth factor receptor	20	60906621	AF172452	11054	20q13.3	Hs.67896	17	regulation of cell growth receptor activity opioid receptor activity cellular_component nucleus cytoplasm membrane
203348_s_at	-0.510	5.178	-2.313	3.509e-02	0.345	-3.804	ETV5	ets variant 5	3	-187246799	BF060791	2119	3q28	Hs.43697	21	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
202290_at	-0.390	7.675	-2.313	3.510e-02	0.345	-3.804	PDAP1	PDGFA associated protein 1	7	-98830524	NM_014891	11333	7q22.1	Hs.632296	8	signal transduction cell proliferation
221924_at	0.327	6.611	2.313	3.510e-02	0.345	-3.804	ZMIZ2	zinc finger, MIZ-type containing 2	7	44755054, 44762311	AW444969	83637	7p13	Hs.600681 Hs.77978	11	protein binding nucleus zinc ion binding ligand-dependent nuclear receptor transcription coactivator activity nuclear replication fork regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
216428_x_at	0.250	4.056	2.313	3.511e-02	0.345	-3.804	KIR3DX1	killer cell immunoglobulin-like receptor, three domains, X1	19	59735720	AK024467	90011	19q13.42	Hs.288520	4
201535_at	-0.400	9.068	-2.313	3.514e-02	0.345	-3.805	UBL3	ubiquitin-like 3	13	-29236545	NM_007106	5412	13q12-q13	Hs.145575	12	intracellular plasma membrane
202511_s_at	-0.297	7.491	-2.313	3.514e-02	0.345	-3.805	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	6	-106739044	AK001899	9474	6q21	Hs.486063	30	autophagic vacuole formation protein binding cytoplasm autophagic vacuole autophagy apoptosis pre-autophagosomal structure membrane post-translational protein modification	Regulation of autophagy RIG-I-like receptor signaling pathway
227246_at	-0.447	5.982	-2.312	3.516e-02	0.346	-3.806	PLRG1	pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)	4	-155677111	BF438014	5356	4q31.2-q32.1	Hs.249996	10	transcription corepressor activity signal transducer activity protein binding nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck
213967_at	0.313	3.134	2.311	3.524e-02	0.346	-3.807	RALYL	RALY RNA binding protein-like	8	85258007, 85258140, 85259654	AI634532	138046	8q21.2	Hs.121663	8	nucleotide binding RNA binding identical protein binding
217982_s_at	-0.258	11.042	-2.311	3.524e-02	0.346	-3.807	MORF4L1	mortality factor 4 like 1	15	76952226	NM_006791	10933	15q24	Hs.374503	25	protein binding nucleus DNA repair response to DNA damage stimulus chromatin modification histone deacetylation Sin3 complex NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation regulation of transcription
218918_at	0.295	5.636	2.311	3.524e-02	0.346	-3.808	MAN1C1	mannosidase, alpha, class 1C, member 1	1	25816545	NM_020379	57134	1p35	Hs.197043	26	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding Golgi apparatus protein amino acid N-linked glycosylation metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds integral to Golgi membrane	N-Glycan biosynthesis Metabolic pathways
204062_s_at	-0.528	5.590	-2.311	3.524e-02	0.346	-3.808	ULK2	unc-51-like kinase 2 (C. elegans)	17	-19614735	BG526973	9706	17p11.2	Hs.168762	10	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation signal transduction axonogenesis transferase activity	Regulation of autophagy mTOR signaling pathway
229399_at	-0.816	4.808	-2.311	3.528e-02	0.346	-3.808	C10orf118	chromosome 10 open reading frame 118	10	-115871963	BF438440	55088	10q25.3	Hs.159066 Hs.603328	9
1568978_s_at	0.315	5.406	2.310	3.528e-02	0.346	-3.808	C11orf21	chromosome 11 open reading frame 21	11	-2274082	BM547346	29125	11p15.5	Hs.559181	2	cytoplasm
215946_x_at	0.346	5.094	2.310	3.528e-02	0.346	-3.808	IGLL3	immunoglobulin lambda-like polypeptide 3	22	24043887	AL022324	91353	22q11.2 22q11.23	Hs.567636	3
219604_s_at	0.233	4.535	2.310	3.529e-02	0.346	-3.809	ZNF3	zinc finger protein 3	7	-99505529, -99499588	NM_017715	7551	7q22.1	Hs.435302	10	transcription factor activity intracellular nucleus nucleus nucleolus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding cell differentiation identical protein binding leukocyte activation metal ion binding
1570515_a_at	-0.867	7.385	-2.310	3.529e-02	0.346	-3.809	FILIP1	filamin A interacting protein 1	6	-76074519	BC029425	27145	6q14.1	Hs.696158	9
224662_at	-0.430	9.452	-2.310	3.530e-02	0.346	-3.809	KIF5B	kinesin family member 5B	10	-32337943	AA630326	3799	10pter-q22.1	Hs.644646	36	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule-based movement cytoplasm organization microtubule binding ciliary rootlet neuron projection membrane-bounded organelle vesicle transport along microtubule perinuclear region of cytoplasm
213546_at	-0.578	6.584	-2.310	3.533e-02	0.346	-3.810	DKFZP586I1420	hypothetical protein DKFZp586I1420	7	30376190	AL050378	222161	7p14.3	Hs.112423	2
203015_s_at	-0.304	4.471	-2.310	3.533e-02	0.346	-3.810	SSX2IP	synovial sarcoma, X breakpoint 2 interacting protein	1	-84882184	AW136988	117178	1p22.3	Hs.22587	14	protein binding nucleus adherens junction cell adhesion cell junction protein complex	Adherens junction
205909_at	0.372	4.225	2.310	3.534e-02	0.346	-3.810	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)	14	-49180028	NM_002692	5427	14q21-q22	Hs.162777	14	DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm DNA-dependent DNA replication DNA repair nucleotide-excision repair, DNA gap filling transferase activity nucleotidyltransferase activity	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
230242_at	0.271	6.105	2.310	3.535e-02	0.346	-3.810	NFASC	neurofascin homolog (chicken)	1	203064404, 203064404, 203179976	AA634220	23114	1q32.1	Hs.13349	28	protein binding plasma membrane cell adhesion integral to membrane	Cell adhesion molecules (CAMs)
212465_at	-0.395	9.209	-2.309	3.537e-02	0.346	-3.811	SETD3	SET domain containing 3	14	-98945893, -98933835	AA524500	84193	14q32.2	Hs.510407	6
221970_s_at	-0.311	7.785	-2.309	3.540e-02	0.347	-3.811	NOL11	nucleolar protein 11	17	63144522	AU158148	25926	17q24.2	Hs.463936	5	nucleus nucleolus
221808_at	-0.361	7.489	-2.309	3.540e-02	0.347	-3.811	RAB9A	RAB9A, member RAS oncogene family	X	13617261	NM_004251	9367	Xp22.2	Hs.495704	24	Golgi membrane nucleotide binding GTPase activity protein binding GTP binding lysosome late endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport
216988_s_at	-0.727	9.541	-2.309	3.541e-02	0.347	-3.812	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	L48722	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
210370_s_at	0.285	3.227	2.309	3.541e-02	0.347	-3.812	LY9	lymphocyte antigen 9	1	159032551, 159032551	AF244129	4063	1q21.3-q22	Hs.403857	17	molecular_function protein binding cell adhesion membrane integral to membrane immunoglobulin mediated immune response
1555905_a_at	-0.957	4.532	-2.308	3.542e-02	0.347	-3.812	C3orf23	chromosome 3 open reading frame 23	3	44354614, 44354947, 44354947	AI147556	285343	3p21.31	Hs.55131	8	mitochondrion
207103_at	-0.185	1.987	-2.308	3.543e-02	0.347	-3.812	KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2	7	119700957	NM_012281	3751	7q31	Hs.654739	39	regulation of action potential voltage-gated ion channel activity voltage-gated potassium channel activity protein binding protein binding plasma membrane ion transport potassium ion transport synaptic transmission voltage-gated potassium channel complex zinc ion binding cell surface integral to membrane potassium ion binding cell projection dendritic spine metal ion binding
209976_s_at	0.280	3.927	2.308	3.543e-02	0.347	-3.812	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	10	135190856	AF182276	1571	10q24.3-qter	Hs.12907	366	endoplasmic reticulum endoplasmic reticulum membrane microsome electron carrier activity membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen drug metabolic process oxygen binding oxygen binding heme binding metal ion binding oxidation reduction	Arachidonic acid metabolism Linoleic acid metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
232141_at	-0.298	6.465	-2.308	3.548e-02	0.347	-3.813	U2AF1	U2 small nuclear RNA auxiliary factor 1	21	-43386134	AU144161	7307	21q22.3	Hs.365116	47	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex zinc ion binding RNA splicing Cajal body metal ion binding RS domain binding
204808_s_at	-0.337	7.234	-2.307	3.551e-02	0.347	-3.814	TMEM5	transmembrane protein 5	12	62459903	NM_014254	10329	12q14.2	Hs.216386	3	integral to plasma membrane membrane
225373_at	0.290	6.153	2.307	3.552e-02	0.347	-3.814	C10orf54	chromosome 10 open reading frame 54	10	-73177318	BE271644	64115	10q22.1	Hs.47382	9	receptor activity membrane integral to membrane
218989_x_at	-0.379	5.463	-2.307	3.552e-02	0.347	-3.814	SLC30A5	solute carrier family 30 (zinc transporter), member 5	5	68425573, 68425637	NM_022902	64924	5q12.1	Hs.631975	10	zinc ion transmembrane transporter activity membrane fraction Golgi apparatus integral to plasma membrane cation transport cobalt ion transport zinc ion transport cellular zinc ion homeostasis zinc ion binding cation transmembrane transporter activity response to zinc ion regulation of proton transport membrane apical plasma membrane secretory granule
243954_at	0.328	3.946	2.307	3.553e-02	0.347	-3.815	LOC285286	hypothetical protein LOC285286	3		AI149729	285286	3p14.2	Hs.559386	1
227257_s_at	-0.463	7.251	-2.307	3.554e-02	0.347	-3.815	C10orf46	chromosome 10 open reading frame 46	10	-120430483	AW973842	143384	10q26.11	Hs.719193	4	ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding
201791_s_at	0.252	5.806	2.306	3.556e-02	0.347	-3.815	DHCR7	7-dehydrocholesterol reductase	11	-70823104	NM_001360	1717	11q13.2-q13.5	Hs.503134	48	blood vessel development protein binding nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane cholesterol biosynthetic process post-embryonic development membrane integral to membrane oxidoreductase activity cell differentiation lung development multicellular organism growth regulation of cell proliferation 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity oxidation reduction	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
206282_at	0.265	2.943	2.306	3.558e-02	0.347	-3.816	NEUROD1	neurogenic differentiation 1	2	-182249438	NM_002500	4760	2q32	Hs.574626 Hs.709709	64	transcription factor activity RNA polymerase II transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent nitric oxide mediated signal transduction multicellular organismal development transcription factor binding response to glucose stimulus anterior/posterior pattern formation transcription activator activity neurogenesis hindbrain development endocrine pancreas development glucose homeostasis camera-type eye development negative regulation of apoptosis sequence-specific DNA binding cell fate commitment positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity embryonic organ morphogenesis regulation of insulin secretion	Maturity onset diabetes of the young
209028_s_at	-0.383	6.373	-2.306	3.558e-02	0.347	-3.816	ABI1	abl-interactor 1	10	-27075530	AF006516	10006	10p11.2	Hs.508148	39	intracellular soluble fraction nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal protein binding negative regulation of cell proliferation peptidyl-tyrosine phosphorylation synaptosome lamellipodium cell junction filopodium growth cone synapse
1561042_at	0.537	4.227	2.306	3.559e-02	0.347	-3.816	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	AF086249	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
201237_at	-0.595	9.127	-2.306	3.560e-02	0.347	-3.816	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	7	116289798	AV685920	830	7q31.2-q31.3	Hs.446123	14	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
216049_at	-0.350	2.824	-2.306	3.561e-02	0.347	-3.817	RHOBTB3	Rho-related BTB domain containing 3	5	95092605	AK023621	22836	5q15	Hs.445030	13	protein binding ATP binding ATPase activity Rab GTPase binding retrograde transport, endosome to Golgi
236979_at	0.190	3.900	2.306	3.562e-02	0.347	-3.817	BCL2L15	BCL2-like 15	1	-114220958	AI821801	440603	1p13.2	Hs.123106	7	apoptosis
228820_at	-0.415	6.222	-2.306	3.562e-02	0.347	-3.817	XPNPEP3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative	22	39583039	BE674036	63929	22q13.31-q13.33	Hs.529163	7	aminopeptidase activity mitochondrion peptidase activity metallopeptidase activity cellular process manganese ion binding metal ion binding
224813_at	-0.433	8.016	-2.306	3.562e-02	0.347	-3.817	WASL	Wiskott-Aldrich syndrome-like	7	-123109232	AL523820	8976	7q31.3	Hs.143728 Hs.708402	58	actin binding small GTPase regulator activity protein binding nucleus nucleolus cytoplasm protein complex assembly cell motion actin polymerization or depolymerization response to bacterium actin cytoskeleton lamellipodium regulation of transcription	Chemokine signaling pathway Adherens junction Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
1562017_at	0.254	3.272	2.305	3.566e-02	0.348	-3.818	LOC100130654	hypothetical protein LOC100130654	17		AK095243	100130654	17q21.2	Hs.636509	1
225893_at	-0.442	8.057	-2.305	3.567e-02	0.348	-3.818	RC3H1	ring finger and CCCH-type zinc finger domains 1	1	-172166974	AL589593	149041	1q25.1	Hs.30258	3	RNA binding protein binding cytoplasm zinc ion binding metal ion binding
226737_at	0.372	7.538	2.305	3.569e-02	0.348	-3.818	SLC25A42	solute carrier family 25, member 42	19	19035807	BG235908	284439	19p13.11	Hs.303669	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
220186_s_at	0.191	5.263	2.304	3.571e-02	0.348	-3.819	PCDH24	protocadherin 24	5	175908970	NM_017675	54825	5q35.2	Hs.4205	9	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane cell junction negative regulation of cell growth
212199_at	-0.262	8.231	-2.304	3.571e-02	0.348	-3.819	MRFAP1L1	Morf4 family associated protein 1-like 1	4	-6760335	AL566962	114932	4p16.1	Hs.593159 Hs.695408	2
215918_s_at	-0.513	6.225	-2.304	3.572e-02	0.348	-3.819	SPTBN1	spectrin, beta, non-erythrocytic 1	2	54536957, 54639034	AA131826	6711	2p21	Hs.503178 Hs.705692	46	actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping
1569895_at	0.269	6.971	2.304	3.574e-02	0.348	-3.820	LOC100133612	similar to hCG1815312	1	3806827	BC016994	100133612	1p36.32	Hs.307652	1
224582_s_at	-0.469	7.062	-2.304	3.574e-02	0.348	-3.820	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	1	-203948569	H09085	64710	1q32.1	Hs.213061 Hs.652429	19	nucleus
228902_at	-0.286	5.240	-2.304	3.575e-02	0.348	-3.820	NUP214	nucleoporin 214kDa	9	132990801	AA516455	8021	9q34.1	Hs.654530	47	transporter activity protein binding nucleus nuclear pore cytosol protein export from nucleus protein transport mRNA transport intracellular protein transmembrane transport
1553672_at	-0.347	3.928	-2.304	3.576e-02	0.348	-3.820	ENAH	enabled homolog (Drosophila)	1	-223741156	NM_145240	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
216916_s_at	0.265	4.943	2.303	3.579e-02	0.348	-3.821	DLGAP2	discs, large (Drosophila) homolog-associated protein 2	8	1436975	AF009204	9228	8p23	Hs.113287	15	protein binding neurofilament plasma membrane cell-cell signaling nerve-nerve synaptic transmission postsynaptic density cell junction synapse postsynaptic membrane
205614_x_at	0.257	6.119	2.303	3.579e-02	0.348	-3.821	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	3	-49696384	NM_020998	4485	3p21	Hs.349110 Hs.512587	31	catalytic activity serine-type endopeptidase activity calcium ion binding extracellular region proteolysis blood coagulation biological_process
207553_at	0.301	3.804	2.303	3.579e-02	0.348	-3.821	OPRK1	opioid receptor, kappa 1	8	-54300828	NM_000912	4986	8q11.2	Hs.106795	46	receptor activity G-protein coupled receptor activity kappa-opioid receptor activity protein binding plasma membrane integral to plasma membrane immune response signal transduction G-protein coupled receptor protein signaling pathway inhibition of adenylate cyclase activity by G-protein signaling synaptic transmission sensory perception behavior viral genome replication	Neuroactive ligand-receptor interaction
200014_s_at	-0.412	9.034	-2.303	3.579e-02	0.348	-3.821	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	14	-20747135	NM_004500	3183	14q11.2	Hs.508848	51	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding nucleus spliceosomal complex RNA splicing identical protein binding
212205_at	-0.439	9.711	-2.303	3.581e-02	0.348	-3.821	H2AFV	H2A histone family, member V	7	-44839737, -44833012	AA534860	94239	7p13	Hs.488189	12	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
205945_at	-1.030	5.699	-2.303	3.581e-02	0.348	-3.821	IL6R	interleukin 6 receptor	1	152644292	NM_000565	3570	1q21	Hs.709210	132	hepatic immune response monocyte chemotaxis positive regulation of leukocyte chemotaxis receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity receptor binding extracellular region plasma membrane interleukin-6 receptor complex acute-phase response integral to membrane apical plasma membrane enzyme binding endocrine pancreas development endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production response to cytokine stimulus positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity regulation of apoptosis positive regulation of osteoblast differentiation positive regulation of anti-apoptosis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium interleukin-6-mediated signaling pathway ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
218921_at	-0.303	5.578	-2.303	3.581e-02	0.348	-3.821	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	11	-395715, -395715	NM_021805	59307	11p15.5	Hs.501624	13	negative regulation of cytokine-mediated signaling pathway transmembrane receptor activity protein binding acute-phase response signal transduction membrane integral to membrane negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation of transcription factor activity negative regulation of chemokine biosynthetic process innate immune response
1563887_at	0.309	3.034	2.303	3.583e-02	0.348	-3.822	INTS4L1	integrator complex subunit 4-like 1	7	64239037	AK057766	285905	7q11.21	Hs.567827	1	binding
202805_s_at	-0.283	5.225	-2.302	3.585e-02	0.348	-3.822	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	16	15950934	NM_004996	4363	16p13.1	Hs.709181	163	nucleotide binding transporter activity ATP binding membrane fraction plasma membrane integral to plasma membrane transport hydrolase activity ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances	ABC transporters
203190_at	0.322	10.394	2.302	3.585e-02	0.348	-3.823	NDUFS8	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)	11	67554669	NM_002496	4728	11q13	Hs.90443	19	NADH dehydrogenase activity iron ion binding mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport response to oxidative stress NADH dehydrogenase (ubiquinone) activity NADH dehydrogenase (ubiquinone) activity electron carrier activity electron transport chain mitochondrial respiratory chain complex I assembly metal ion binding 4 iron, 4 sulfur cluster binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
213945_s_at	0.231	4.118	2.302	3.587e-02	0.348	-3.823	NUP210	nucleoporin 210kDa	3	-13332736	AA909765	23225	3p25.1	Hs.475525	24	protein binding nucleus nuclear pore endoplasmic reticulum protein transport membrane integral to membrane mRNA transport intracellular protein transmembrane transport
221773_at	0.579	6.858	2.302	3.587e-02	0.348	-3.823	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	12	95112337	AW575374	2004	12q23	Hs.46523	18	angiogenesis transcription factor activity transcription corepressor activity protein binding nucleus nucleolus mitochondrion regulation of transcription, DNA-dependent signal transduction negative regulation of transcription purine-rich negative regulatory element binding wound healing
225844_at	-0.438	7.694	-2.302	3.589e-02	0.348	-3.823	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	2	75039282	NM_019896	56655	2p12	Hs.469060	5	DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
212824_at	-0.349	6.286	-2.302	3.589e-02	0.348	-3.824	FUBP3	far upstream element (FUSE) binding protein 3	9	132444780	U69127	8939	9q34.11-q34.12	Hs.673029 Hs.98751	6	DNA binding RNA binding protein binding nucleus transcription activator activity regulation of transcription
231810_at	0.366	6.077	2.301	3.592e-02	0.348	-3.824	BRI3BP	BRI3 binding protein	12	124044146	BG106919	140707	12q24.31	Hs.596464	5	membrane integral to membrane
212987_at	-0.293	9.153	-2.301	3.593e-02	0.348	-3.824	FBXO9	F-box protein 9	6	53037754, 53038215, 53043729	AL031178	26268	6p12.3-p11.2	Hs.216653	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein ubiquitination modification-dependent protein catabolic process
206893_at	0.210	2.071	2.301	3.593e-02	0.348	-3.824	SALL1	sal-like 1 (Drosophila)	16	-49727386, -49727386	NM_002968	6299	16q12.1	Hs.135787	29	ureteric bud development transcription factor activity intracellular nucleus zinc ion binding anatomical structure morphogenesis inductive cell-cell signaling regulation of transcription metal ion binding
225632_s_at	0.396	5.494	2.301	3.594e-02	0.348	-3.825	RAB43	RAB43, member RAS oncogene family	3	-130289107	BE736242	339122	3q21.3	Hs.709807	6	nucleotide binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport
203752_s_at	-0.431	8.942	-2.301	3.594e-02	0.348	-3.825	JUND	jun D proto-oncogene	19	-18251562	NM_005354	3727	19p13.2	Hs.2780	67	chromatin osteoblast development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding positive regulation of osteoblast differentiation protein dimerization activity	MAPK signaling pathway
219385_at	0.264	5.211	2.301	3.595e-02	0.348	-3.825	SLAMF8	SLAM family member 8	1	158063102	NM_020125	56833	1q23.2	Hs.438683	9	membrane integral to membrane
235339_at	-0.436	4.440	-2.300	3.598e-02	0.349	-3.826	SETDB2	SET domain, bifurcated 2	13	48916429, 48923688	W65369	83852	13q14	Hs.631789 Hs.633823	6	DNA binding nucleus methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity	Lysine degradation
214053_at	-0.909	5.754	-2.300	3.599e-02	0.349	-3.826	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	2	-211948686	AW772192	2066	2q33.3-q34	Hs.390729	112	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway nervous system development heart development cell proliferation membrane integral to membrane basolateral plasma membrane transferase activity cell fate commitment	ErbB signaling pathway Calcium signaling pathway Endocytosis
212817_at	-0.408	7.814	-2.300	3.600e-02	0.349	-3.826	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	9	34979724, 34980266	AK023253	25822	9p13.3	Hs.237506	5	protein folding response to unfolded protein heat shock protein binding unfolded protein binding
218032_at	-0.547	8.248	-2.300	3.602e-02	0.349	-3.827	SNN	stannin	16	11669801	AF070673	8303	16p13	Hs.700592	11	response to stress response to abiotic stimulus membrane integral to membrane
203929_s_at	-0.331	8.456	-2.300	3.602e-02	0.349	-3.827	MAPT	microtubule-associated protein tau	17	41327543	AI056359	4137	17q21.1	Hs.101174	545	microtubule cytoskeleton organization microtubule cytoskeleton organization structural constituent of cytoskeleton cytoplasm cytosol cytoskeleton microtubule microtubule associated complex plasma membrane plasma membrane negative regulation of microtubule depolymerization microtubule binding microtubule binding lipoprotein binding SH3 domain binding enzyme binding axon axon growth cone growth cone positive regulation of microtubule polymerization positive regulation of microtubule polymerization apolipoprotein E binding identical protein binding cell projection tubulin complex tubulin complex positive regulation of axon extension positive regulation of axon extension generation of neurons	MAPK signaling pathway Alzheimer's disease
1565756_a_at	0.316	4.369	2.300	3.602e-02	0.349	-3.827	MAP1D	methionine aminopeptidase 1D	2	172573049	AA333781	254042	2q31.1	Hs.298250	4	aminopeptidase activity mitochondrion proteolysis peptidase activity metalloexopeptidase activity cellular process peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding
222798_at	0.573	7.204	2.300	3.603e-02	0.349	-3.827	PTER	phosphotriesterase related	10	16518972	BF112019	9317	10p12	Hs.444321 Hs.716660	6	zinc ion binding catabolic process hydrolase activity, acting on ester bonds metal ion binding
1552501_a_at	0.237	5.869	2.299	3.608e-02	0.349	-3.828	GPBAR1	G protein-coupled bile acid receptor 1	2	218833982	NM_170699	151306	2q35	Hs.160954	10	receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
224801_at	-0.444	6.695	-2.299	3.611e-02	0.349	-3.829	NDFIP2	Nedd4 family interacting protein 2	13	78953259	AI655642	54602	13q31.1	Hs.525093	12	signal transducer activity protein binding cytoplasm mitochondrion endosome endoplasmic reticulum Golgi apparatus negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm WW domain binding negative regulation of protein transport
203883_s_at	-0.240	7.209	-2.298	3.612e-02	0.349	-3.829	RAB11FIP2	RAB11 family interacting protein 2 (class I)	10	-119754418	BG249608	22841	10q26.11	Hs.173656	20	protein binding endosome plasma membrane protein transport	Endocytosis
202084_s_at	-0.434	9.391	-2.298	3.612e-02	0.349	-3.829	SEC14L1	SEC14-like 1 (S. cerevisiae)	17	72648599, 72692889	NM_003003	6397	17q25.1-q25.2	Hs.464184	11	binding Golgi apparatus membrane
201511_at	-0.229	7.540	-2.298	3.615e-02	0.349	-3.830	AAMP	angio-associated, migratory cell protein	2	-218837095	NM_001087	14	2q35	Hs.83347	11	angiogenesis cytoplasm plasma membrane multicellular organismal development heparin binding cell surface positive regulation of endothelial cell migration smooth muscle cell migration cell differentiation
201336_at	-0.326	9.552	-2.298	3.617e-02	0.349	-3.830	VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	1	7753915	BC003570	9341	1p36.23	Hs.66708	26	protein complex assembly vesicle docking during exocytosis membrane fusion membrane integral to membrane synaptosome cell junction synapse	SNARE interactions in vesicular transport
205135_s_at	-0.367	4.397	-2.298	3.618e-02	0.349	-3.830	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	13	-44411383	AL049842	26747	13q14	Hs.525006	11	box C/D snoRNP assembly DNA binding intracellular nucleus perichromatin fibrils nucleolus RNA processing transcription elongation factor complex zinc ion binding nuclear matrix cytosolic ribosome snoRNA binding protein binding, bridging identical protein binding positive regulation of transcription from RNA polymerase II promoter metal ion binding presynaptic active zone pre-snoRNP complex
1552712_a_at	0.385	3.756	2.297	3.620e-02	0.349	-3.831	NMNAT2	nicotinamide nucleotide adenylyltransferase 2	1	-181484001, -181484001	NM_170706	23057	1q25	Hs.497123	9	nucleotide binding magnesium ion binding nicotinamide-nucleotide adenylyltransferase activity nicotinate-nucleotide adenylyltransferase activity ATP binding cytoplasm Golgi apparatus biosynthetic process NAD biosynthetic process transferase activity nucleotidyltransferase activity pyridine nucleotide biosynthetic process	Nicotinate and nicotinamide metabolism Metabolic pathways
47083_at	0.250	7.074	2.297	3.622e-02	0.350	-3.831	C7orf26	chromosome 7 open reading frame 26	7	6596439	AI280108	79034	7p22.1	Hs.487511	4
219825_at	0.643	4.693	2.297	3.623e-02	0.350	-3.832	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1	2	-72209874	NM_019885	56603	2p13.2	Hs.91546	11	cell fate determination retinoic acid binding endoplasmic reticulum microsome male meiosis spermatogenesis retinoic acid 4-hydroxylase activity electron carrier activity proximal/distal pattern formation membrane heme binding embryonic limb morphogenesis retinoic acid catabolic process metal ion binding negative regulation of retinoic acid receptor signaling pathway oxidation reduction	Retinol metabolism
204921_at	0.291	6.965	2.297	3.624e-02	0.350	-3.832	GAS8	growth arrest-specific 8	16	88616508, 88616508	NM_001481	2622	16q24.3	Hs.431792	7	molecular_function protein binding cytoplasm Golgi apparatus cytoskeleton microtubule cilium microtubule basal body negative regulation of cell proliferation microtubule-based flagellum sperm motility
228418_at	-0.359	4.605	-2.297	3.624e-02	0.350	-3.832	EXOC5	exocyst complex component 5	14	-56738946	BF509391	10640	14q22.3	Hs.715522	15	cytoplasm exocytosis post-Golgi vesicle-mediated transport protein transport vesicle docking
201590_x_at	-0.642	9.579	-2.297	3.625e-02	0.350	-3.832	ANXA2	annexin A2	15	-58426642, -58426641	NM_004039	302	15q21-q22	Hs.511605	137	skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm
205421_at	-1.688	5.330	-2.296	3.627e-02	0.350	-3.833	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3	6	160689414	NM_021977	6581	6q26-q27	Hs.567337	33	transporter activity protein binding membrane fraction integral to plasma membrane ion transport ion transmembrane transporter activity quaternary ammonium group transmembrane transporter activity quaternary ammonium group transport monoamine transport membrane regulation of appetite histamine uptake
200761_s_at	-0.376	10.622	-2.296	3.631e-02	0.350	-3.834	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	3	69216779	NM_006407	10550	3p14	Hs.518060 Hs.716493	30	protein binding cytoplasm endoplasmic reticulum L-glutamate transport membrane integral to membrane
204888_s_at	0.338	4.686	2.295	3.633e-02	0.350	-3.834	NEURL	neuralized homolog (Drosophila)	10	105243724	AA772093	9148	10q25.1	Hs.716382	8	protein binding cytoplasm nervous system development zinc ion binding metal ion binding perinuclear region of cytoplasm
221825_at	-0.423	7.512	-2.295	3.633e-02	0.350	-3.834	ANGEL2	angel homolog 2 (Drosophila)	1	-211232146	AU151793	90806	1q32.3	Hs.157078	3
240329_at	0.277	4.539	2.295	3.635e-02	0.350	-3.835	LOC727916	hypothetical protein LOC727916	6		AW136267	727916	6q12	Hs.706850	1
211037_s_at	0.304	4.159	2.295	3.636e-02	0.350	-3.835	MBOAT7	membrane bound O-acyltransferase domain containing 7	19	-59373852, -59368918	BC006309	79143	19q13.4	Hs.467279	8	acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
244180_at	0.291	5.480	2.295	3.636e-02	0.350	-3.835	ZNF793	zinc finger protein 793	19	42689680	AI039201	390927	19q13.12	Hs.568010	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1563117_at	0.320	3.593	2.295	3.638e-02	0.350	-3.835	LOC388456	hypothetical gene supported by BC039671	18		BC039671	388456	18p11.32	Hs.407666	1
228935_at	0.241	4.055	2.295	3.639e-02	0.350	-3.835	SLC4A8	solute carrier family 4, sodium bicarbonate cotransporter, member 8	12	50104860, 50104860	AI570494	9498	12q13.13	Hs.370636	13	transporter activity inorganic anion exchanger activity sodium ion transport anion transport anion transmembrane transporter activity antiporter activity membrane integral to membrane sodium ion binding
218373_at	-0.373	9.125	-2.295	3.639e-02	0.350	-3.836	AKTIP	AKT interacting protein	16	-52082692	NM_022476	64400	16q12.2	Hs.380897	14	protein binding cytoplasm plasma membrane apoptosis endosome organization lysosome organization endosome to lysosome transport protein transport small conjugating protein ligase activity HOPS complex post-translational protein modification early endosome to late endosome transport regulation of protein metabolic process FHF complex
238190_at	-0.200	5.604	-2.294	3.640e-02	0.350	-3.836	TUFM	Tu translation elongation factor, mitochondrial	16	-28761232	AI143752	7284	16p11.2	Hs.12084	18	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding intracellular mitochondrion translational elongation mitochondrial nucleoid
219999_at	-0.344	6.195	-2.294	3.644e-02	0.351	-3.837	MAN2A2	mannosidase, alpha, class 2A, member 2	15	89248423	NM_018621	4122	15q26.1	Hs.116459	20	Golgi membrane alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process metabolic process zinc ion binding membrane integral to membrane carbohydrate binding metal ion binding	N-Glycan biosynthesis Metabolic pathways
216678_at	0.305	6.013	2.293	3.650e-02	0.351	-3.838	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)	3	130641657, 130641657	AK000773	55764	3q21	Hs.655284	6	cytoplasm
1552660_a_at	-0.438	5.137	-2.293	3.651e-02	0.351	-3.838	C5orf22	chromosome 5 open reading frame 22	5	31568129	BC021215	55322	5p13.3	Hs.519246	7
221751_at	-0.345	7.366	-2.292	3.654e-02	0.351	-3.839	SLC2A3P1	solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 1	5		AL565516	100128062	5q34	Hs.388400	2
1554828_at	0.264	3.494	2.292	3.654e-02	0.351	-3.839	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	4	54790020	BC015186	5156	4q11-q13	Hs.74615	173	nucleotide binding in utero embryonic development cell activation receptor activity platelet-derived growth factor alpha-receptor activity vascular endothelial growth factor receptor activity platelet-derived growth factor receptor binding ATP binding integral to plasma membrane membrane transferase activity peptidyl-tyrosine phosphorylation extracellular matrix organization lung development positive regulation of cell migration male genitalia development odontogenesis of dentine-containing tooth protein homodimerization activity positive regulation of DNA replication protein amino acid autophosphorylation protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding skeletal system morphogenesis palate development face morphogenesis	MAPK signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interaction Endocytosis Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Glioma Prostate cancer Melanoma
228132_at	-0.398	8.651	-2.292	3.656e-02	0.351	-3.840	ABLIM2	actin binding LIM protein family, member 2	4	-8059647, -8017936	AI240129	84448	4p16.1	Hs.233404	9	actin binding cytoplasm cytoskeleton organization zinc ion binding actin cytoskeleton myofibril positive regulation of transcription from RNA polymerase II promoter metal ion binding	Axon guidance
237202_at	0.242	6.705	2.292	3.657e-02	0.351	-3.840	PGPEP1	pyroglutamyl-peptidase I	19	18312407	AI810572	54858	19p13.11	Hs.131776	8	cytoplasm proteolysis peptidase activity cysteine-type peptidase activity
217452_s_at	-0.195	1.875	-2.292	3.658e-02	0.351	-3.840	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	1	-191414482	Y15014	8707	1q31	Hs.518834 Hs.716598	13	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity oligosaccharide biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
219319_at	0.252	5.926	2.291	3.662e-02	0.351	-3.841	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	NM_022462	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
208091_s_at	-0.347	8.084	-2.291	3.664e-02	0.351	-3.842	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	7	-55505799	NM_030796	81552	7p11.2	Hs.488307	17
232922_s_at	0.332	5.661	2.291	3.664e-02	0.351	-3.842	SLC17A9	solute carrier family 17, member 9	20	61054443	BG419965	63910	20q13.33	Hs.512686	7	transporter activity transport exocytosis membrane integral to membrane
232521_at	-0.346	5.377	-2.291	3.665e-02	0.351	-3.842	PCSK7	proprotein convertase subtilisin/kexin type 7	11	-116580997	AK027156	9159	11q23-q24	Hs.410977 Hs.648612 Hs.709588	28	serine-type endopeptidase activity Golgi apparatus proteolysis peptidase activity membrane integral to membrane peptide hormone processing integral to Golgi membrane
203820_s_at	-0.410	3.424	-2.291	3.666e-02	0.351	-3.842	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	7	-23316352	NM_006547	10643	7p11	Hs.700696	37	nucleotide binding RNA binding nucleus cytoplasm anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process translation regulator activity mRNA 5'-UTR binding
242738_s_at	-0.437	6.378	-2.290	3.668e-02	0.352	-3.842	ZFHX3	zinc finger homeobox 3	16	-71374286	BG402859	463	16q22.3-q23.1	Hs.598297	26	negative regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor activity, enhancer binding intracellular nucleus transcription factor complex mitochondrion regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity sequence-specific DNA binding metal ion binding
204156_at	-0.406	5.842	-2.290	3.668e-02	0.352	-3.843	QSK	serine/threonine-protein kinase QSK	11	-116219327	AA044154	23387	11q23.3	Hs.167451	14	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
213625_at	0.250	4.722	2.290	3.673e-02	0.352	-3.844	ZKSCAN4	zinc finger with KRAB and SCAN domains 4	6	-28320468	AW190088	387032	6p21.33-p21.31	Hs.44720	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
233884_at	0.544	4.537	2.290	3.674e-02	0.352	-3.844	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	1	-41748270	AL512747	59269	1p34	Hs.648369 Hs.715958	12	DNA binding intracellular nucleus cytoplasm zinc ion binding transcription activator activity positive regulation of transcription metal ion binding
231745_at	0.389	4.234	2.290	3.675e-02	0.352	-3.844	GPR55	G protein-coupled receptor 55	2	-231480286	NM_005683	9290	2q37	Hs.114545	8	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway
225509_at	-0.415	7.304	-2.289	3.675e-02	0.352	-3.844	SAP30L	SAP30-like	5	153805709	AI862477	79685	5q33.2	Hs.592566	8	nucleus nucleolus regulation of transcription
206401_s_at	-0.625	7.416	-2.289	3.678e-02	0.352	-3.845	MAPT	microtubule-associated protein tau	17	41327543	J03778	4137	17q21.1	Hs.101174	545	microtubule cytoskeleton organization microtubule cytoskeleton organization structural constituent of cytoskeleton cytoplasm cytosol cytoskeleton microtubule microtubule associated complex plasma membrane plasma membrane negative regulation of microtubule depolymerization microtubule binding microtubule binding lipoprotein binding SH3 domain binding enzyme binding axon axon growth cone growth cone positive regulation of microtubule polymerization positive regulation of microtubule polymerization apolipoprotein E binding identical protein binding cell projection tubulin complex tubulin complex positive regulation of axon extension positive regulation of axon extension generation of neurons	MAPK signaling pathway Alzheimer's disease
1554940_a_at	0.290	4.271	2.289	3.679e-02	0.352	-3.845	LOC388882	hypothetical LOC388882	22		BC036910	388882	22q11.23	Hs.542766	1
204791_at	-0.387	7.143	-2.289	3.679e-02	0.352	-3.845	NR2C1	nuclear receptor subfamily 2, group C, member 1	12	-93948315, -93938188	NM_003297	7181	12q22	Hs.108301 Hs.707524	17	negative regulation of transcription from RNA polymerase II promoter transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity protein homodimerization activity histone deacetylase binding sequence-specific DNA binding metal ion binding
200848_at	-0.432	8.701	-2.289	3.679e-02	0.352	-3.845	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	AA479488	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
220721_at	0.273	4.428	2.288	3.682e-02	0.352	-3.846	ZNF614	zinc finger protein 614	19	-57208389	NM_025040	80110	19q13.41	Hs.292336	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
242548_x_at	-0.416	4.813	-2.288	3.682e-02	0.352	-3.846	ANKRD37	ankyrin repeat domain 37	4	186554833	BF245661	353322	4q35.1	Hs.508154	4	nucleus cytoplasm
212716_s_at	0.243	11.408	2.288	3.683e-02	0.352	-3.846	EIF3K	eukaryotic translation initiation factor 3, subunit K	19	43801561	AW083133	27335	19q13.2	Hs.314359	15	translation initiation factor activity translation initiation factor activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex regulation of translational initiation ribosome binding
236876_at	0.242	5.615	2.288	3.684e-02	0.352	-3.846	H1FNT	H1 histone family, member N, testis-specific	12	47009029	AW013835	341567	12q13.11	Hs.155833	3	nucleotide binding nuclear chromatin DNA binding ATP binding nucleus chromosome multicellular organismal development spermatogenesis spermatid nucleus elongation cell differentiation chromosome condensation sperm chromatin condensation
220027_s_at	0.386	6.588	2.288	3.685e-02	0.352	-3.847	RASIP1	Ras interacting protein 1	19	-53915653	NM_017805	54922	19q13.33	Hs.233955	4	cytoplasm Golgi apparatus Golgi stack signal transduction perinuclear region of cytoplasm
207973_x_at	0.286	3.444	2.288	3.686e-02	0.352	-3.847	ACRV1	acrosomal vesicle protein 1	11	-125047438	NM_020110	56	11q23-q24	Hs.169222 Hs.596575	12	acrosomal vesicle multicellular organismal development
244413_at	0.228	3.652	2.288	3.687e-02	0.352	-3.847	CLECL1	C-type lectin-like 1	12	-9766357	AW237307	160365	12p13.31	Hs.560087	3	binding sugar binding plasma membrane integral to membrane
225818_s_at	-0.493	5.703	-2.287	3.691e-02	0.352	-3.848	TBRG1	transforming growth factor beta regulator 1	11	123997951	BG286461	84897	11q24.2	Hs.436410	11	DNA binding protein binding nucleus DNA replication cell cycle cell cycle arrest negative regulation of cell proliferation nucleolus to nucleoplasm transport protein stabilization
216968_at	0.250	5.424	2.287	3.691e-02	0.352	-3.848	MASP2	mannan-binding lectin serine peptidase 2	1	-11027441, -11009166	Y18284	10747	1p36.3-p36.2	Hs.655645	51	complement activation, lectin pathway complement activation, lectin pathway serine-type endopeptidase activity calcium ion binding extracellular region extracellular region proteolysis complement activation, classical pathway peptidase activity calcium-dependent protein binding	Complement and coagulation cascades
200845_s_at	-0.375	10.935	-2.287	3.692e-02	0.352	-3.848	PRDX6	peroxiredoxin 6	1	171713108	NM_004905	9588	1q25.1	Hs.120	40	phospholipase A2 activity nucleus cytoplasm lysosome cytosol response to oxidative stress phospholipid catabolic process lipid catabolic process oxidoreductase activity hydrolase activity cytoplasmic vesicle cell redox homeostasis peroxiredoxin activity oxidation reduction	Phenylalanine metabolism Methane metabolism Phenylpropanoid biosynthesis Tropane, piperidine and pyridine alkaloid biosynthesis Biosynthesis of phenylpropanoids Metabolic pathways
204287_at	0.282	6.299	2.287	3.693e-02	0.352	-3.848	SYNGR1	synaptogyrin 1	22	38075899, 38075899, 38090120	NM_004711	9145	22q13.1	Hs.216226	13	integral to plasma membrane membrane cell junction melanosome synapse
211258_s_at	0.289	5.291	2.287	3.693e-02	0.352	-3.849	TGFA	transforming growth factor, alpha	2	-70527924	AF149096	7039	2p13	Hs.170009	117	activation of MAPK activity angiogenesis glycoprotein binding MAP kinase kinase activity signal transducer activity extracellular region extracellular space plasma membrane growth factor activity cell proliferation cell surface integral to membrane positive regulation of epidermal growth factor receptor activity positive regulation of mitosis positive regulation of epithelial cell proliferation	ErbB signaling pathway Pathways in cancer Renal cell carcinoma Pancreatic cancer Glioma Prostate cancer Non-small cell lung cancer
224782_at	-0.320	8.073	-2.287	3.695e-02	0.352	-3.849	ZMAT2	zinc finger, matrin type 2	5	140060215	AA205643	153527	5q31.3	Hs.350194	4	DNA binding intracellular nucleus zinc ion binding metal ion binding
219187_at	-0.215	5.713	-2.287	3.696e-02	0.352	-3.849	FKBPL	FK506 binding protein like	6	-32204461, -3503650	NM_022110	63943	6p21.3	Hs.520042	7	binding cellular_component extracellular space protein folding JAK-STAT cascade nervous system development brain development aging response to radiation basal plasma membrane positive regulation of smooth muscle cell proliferation advanced glycation end-product receptor activity
1554541_a_at	0.260	4.981	2.286	3.697e-02	0.352	-3.850	GPRIN2	G protein regulated inducer of neurite outgrowth 2	10	46413551	BC011672	9721	10q11.22	Hs.523375	7
218093_s_at	-0.500	8.468	-2.286	3.698e-02	0.352	-3.850	ANKRD10	ankyrin repeat domain 10	13	-110328887	NM_017664	55608	13q34	Hs.525163	2
211570_s_at	-0.363	6.748	-2.285	3.704e-02	0.353	-3.851	RAPSN	receptor-associated protein of the synapse	11	-47415890	BC004196	5913	11p11.2-p11.1	Hs.81218	32	protein binding cytoplasm Golgi apparatus cytoskeleton plasma membrane synaptic transmission zinc ion binding cell junction neuromuscular junction acetylcholine receptor binding postsynaptic membrane metal ion binding
219014_at	0.474	4.372	2.285	3.706e-02	0.353	-3.852	PLAC8	placenta-specific 8	4	-84234330, -84230234, -84230234	NM_016619	51316	4q21.22	Hs.546392	5
207971_s_at	-0.371	5.573	-2.285	3.706e-02	0.353	-3.852	CEP68	centrosomal protein 68kDa	2	65136998	NM_015147	23177	2p14	Hs.709257	12	centrosome
1565484_x_at	0.548	6.580	2.284	3.711e-02	0.353	-3.853	EGFR	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	7	55054218, 55054218, 55054218, 55054218	AF277897	1956	7p12	Hs.488293	1458	nucleotide binding cell morphogenesis ossification double-stranded DNA binding MAP/ERK kinase kinase activity transmembrane receptor activity epidermal growth factor receptor activity epidermal growth factor receptor activity ATP binding extracellular region extracellular space intracellular nucleus cytoplasm endosome plasma membrane plasma membrane response to stress cell surface receptor linked signal transduction epidermal growth factor receptor signaling pathway activation of phospholipase C activity salivary gland morphogenesis integral to membrane basolateral plasma membrane cell-cell adhesion transferase activity protein phosphatase binding AP-2 adaptor complex endocytic vesicle nitric-oxide synthase regulator activity positive regulation of cell migration positive regulation of cyclin-dependent protein kinase activity during G1/S positive regulation of phosphorylation identical protein binding activation of phospholipase A2 activity by calcium-mediated signaling positive regulation of MAP kinase activity positive regulation of nitric oxide biosynthetic process protein amino acid autophosphorylation protein heterodimerization activity positive regulation of epithelial cell proliferation regulation of peptidyl-tyrosine phosphorylation regulation of nitric-oxide synthase activity actin filament binding protein insertion into membrane response to UV-A Shc-EGFR complex	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interaction Endocytosis Dorso-ventral axis formation Focal adhesion Adherens junction Gap junction Regulation of actin cytoskeleton GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Non-small cell lung cancer
231958_at	0.257	5.137	2.284	3.713e-02	0.353	-3.853	C3orf31	chromosome 3 open reading frame 31	3	-11806918	AW969235	132001	3p25.2	Hs.475472	4	mitochondrion protein transport protein import into mitochondrial matrix extrinsic to mitochondrial inner membrane
225086_at	-0.312	7.742	-2.284	3.713e-02	0.353	-3.853	FAM98B	family with sequence similarity 98, member B	15	36533619, 36533619	BF679966	283742	15q14	Hs.6799	5	protein binding
214985_at	-0.278	3.113	-2.284	3.714e-02	0.353	-3.853	EXT1	exostoses (multiple) 1	8	-118880782	AF070571	2131	8q24.11-q24.13	Hs.492618	53	Golgi membrane skeletal system development ossification protein binding endoplasmic reticulum Golgi apparatus glycosaminoglycan biosynthetic process signal transduction gastrulation endoderm development mesoderm development heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process membrane integral to membrane integral to endoplasmic reticulum membrane heparan sulfate N-acetylglucosaminyltransferase activity protein homodimerization activity protein heterodimerization activity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	Heparan sulfate biosynthesis Metabolic pathways
225466_at	-0.340	7.832	-2.284	3.714e-02	0.353	-3.853	PATL1	protein associated with topoisomerase II homolog 1 (yeast)	11	-59160767	BG291961	219988	11q12.1	Hs.591960	8	cytoplasmic mRNA processing body cytoplasm	RNA degradation
226590_at	0.362	5.294	2.284	3.715e-02	0.353	-3.854	ZNF618	zinc finger protein 618	9	115678382	AA910497	114991	9q32	Hs.349208	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity
212203_x_at	0.445	9.583	2.284	3.716e-02	0.353	-3.854	IFITM3	interferon induced transmembrane protein 3 (1-8U)	11	-309672	BF338947	10410	11p15.5	Hs.374650	13	plasma membrane immune response response to biotic stimulus integral to membrane
218474_s_at	-0.294	6.486	-2.284	3.716e-02	0.353	-3.854	KCTD5	potassium channel tetramerisation domain containing 5	16	2672495	NM_018992	54442	16p13.3	Hs.61960	9	voltage-gated potassium channel activity protein binding nucleus cytoplasm potassium ion transport voltage-gated potassium channel complex membrane interspecies interaction between organisms
203017_s_at	-0.491	4.946	-2.284	3.716e-02	0.353	-3.854	SSX2IP	synovial sarcoma, X breakpoint 2 interacting protein	1	-84882184	R52678	117178	1p22.3	Hs.22587	14	protein binding nucleus adherens junction cell adhesion cell junction protein complex	Adherens junction
228760_at	-0.380	7.568	-2.284	3.717e-02	0.353	-3.854	SFRS2B	splicing factor, arginine/serine-rich 2B	11	94439703	AV725947	10929	11q22	Hs.476680 Hs.713908	6	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
219276_x_at	-0.476	6.639	-2.284	3.717e-02	0.353	-3.854	C9orf82	chromosome 9 open reading frame 82	9	-26830682	NM_024828	79886	9p21.2	Hs.178357	10
211520_s_at	0.204	2.247	2.283	3.718e-02	0.353	-3.854	GRIA1	glutamate receptor, ionotropic, AMPA 1	5	152850276	M64752	2890	5q31.1 5q33	Hs.519693	58	receptor activity ion channel activity extracellular-glutamate-gated ion channel activity membrane fraction endoplasmic reticulum plasma membrane ion transport signal transduction synaptic transmission kainate selective glutamate receptor activity integral to membrane cell junction alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction Long-term potentiation Long-term depression Amyotrophic lateral sclerosis (ALS)
210887_s_at	0.194	5.595	2.283	3.718e-02	0.353	-3.854	EVC	Ellis van Creveld syndrome	4	5763824	AF216185	2121	4p16	Hs.646899 Hs.670028	13	skeletal system development muscle organ development membrane integral to membrane
226523_at	0.274	6.648	2.283	3.719e-02	0.353	-3.855	TAGLN	transgelin	11	116575249	AI082237	6876	11q23.2	Hs.410977	25	actin binding protein binding cytoplasm muscle organ development
230992_at	0.533	5.744	2.283	3.719e-02	0.353	-3.855	BTNL9	butyrophilin-like 9	5	180399830	T47960	153579	5q35.3	Hs.546502	4	membrane integral to membrane
218610_s_at	-0.528	4.349	-2.283	3.720e-02	0.353	-3.855	CPPED1	calcineurin-like phosphoesterase domain containing 1	16	-12661156	NM_018340	55313	16p13.12	Hs.460002	4	hydrolase activity metal ion binding
212166_at	-0.228	7.750	-2.283	3.720e-02	0.353	-3.855	XPO7	exportin 7	8	21833125, 21879694	H38643	23039	8p21	Hs.172685	9	protein import into nucleus, docking nuclear export signal receptor activity nucleus nuclear pore cytoplasm protein export from nucleus protein transporter activity mRNA transport intracellular protein transmembrane transport
211028_s_at	0.267	6.022	2.283	3.721e-02	0.353	-3.855	KHK	ketohexokinase (fructokinase)	2	27163114	BC006233	3795	2p23.3	Hs.567297	20	nucleotide binding ketohexokinase activity protein binding ATP binding cytoplasm carbohydrate metabolic process kinase activity transferase activity	Fructose and mannose metabolism Metabolic pathways
217803_at	-0.565	7.676	-2.283	3.724e-02	0.353	-3.856	GOLPH3	golgi phosphoprotein 3 (coat-protein)	5	-32160580	NM_022130	64083	5p13.3	Hs.408909	6	protein binding cytoplasm mitochondrion Golgi apparatus trans-Golgi network membrane positive regulation of TOR signaling pathway
212918_at	-0.355	6.481	-2.282	3.725e-02	0.353	-3.856	RECQL	RecQ protein-like (DNA helicase Q1-like)	12	-21513111	AI962943	5965	12p12	Hs.235069	29	nucleotide binding DNA strand renaturation DNA strand annealing activity DNA binding ATP-dependent DNA helicase activity protein binding ATP binding nucleus DNA repair DNA recombination hydrolase activity
200964_at	-0.417	7.829	-2.282	3.725e-02	0.353	-3.856	UBA1	ubiquitin-like modifier activating enzyme 1	X	46935142, 46938144	NM_003334	7317	Xp11.23	Hs.533273	53	nucleotide binding protein binding ATP binding protein modification process metabolic process cell death small protein activating enzyme activity ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis Parkinson's disease
221778_at	-0.424	7.662	-2.282	3.725e-02	0.353	-3.856	JHDM1D	jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)	7	-139431014	BE217882	80853	7q34	Hs.308710	3	protein binding zinc ion binding metal ion binding
212549_at	-0.438	7.854	-2.282	3.729e-02	0.353	-3.857	STAT5B	signal transducer and activator of transcription 5B	17	-37604720	BE645861	6777	17q11.2	Hs.719121	128	allantoin metabolic process luteinization natural killer cell differentiation transcription factor activity signal transducer activity calcium ion binding protein binding nucleus cytoplasm citrate metabolic process 2-oxoglutarate metabolic process succinate metabolic process oxaloacetate metabolic process isoleucine metabolic process valine metabolic process creatine metabolic process fatty acid metabolic process signal transduction female pregnancy lactation positive regulation of cell proliferation regulation of steroid metabolic process cytokine-mediated signaling pathway taurine metabolic process lipid storage regulation of cell adhesion regulation of epithelial cell differentiation response to estradiol stimulus cellular response to hormone stimulus T cell differentiation in the thymus glucocorticoid receptor binding positive regulation of multicellular organism growth positive regulation of activated T cell proliferation progesterone metabolic process T cell homeostasis negative regulation of apoptosis positive regulation of interleukin-2 biosynthetic process positive regulation of B cell differentiation positive regulation of gamma-delta T cell differentiation negative regulation of erythrocyte differentiation positive regulation of survival gene product expression positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter creatinine metabolic process development of secondary female sexual characteristics development of secondary male sexual characteristics Peyer's patch development positive regulation of inflammatory response JAK-STAT cascade involved in growth hormone signaling pathway	ErbB signaling pathway Chemokine signaling pathway Jak-STAT signaling pathway Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia
223853_at	-0.478	4.122	-2.282	3.729e-02	0.353	-3.857	BVES	blood vessel epicardial substance	6	-105651391, -105651391	AF204172	11149	6q21	Hs.221660	6	muscle organ development membrane integral to membrane
1552293_at	0.277	4.680	2.282	3.731e-02	0.353	-3.857	TMEM196	transmembrane protein 196	7	-19725463	NM_152774	256130	7p21.1	Hs.487670	1	membrane integral to membrane
238461_at	-0.933	5.652	-2.281	3.735e-02	0.354	-3.858	EIF4E3	eukaryotic translation initiation factor 4E family member 3	3	-71811131, -71811131, -71811131, -71811131	AA228031	317649	3p14	Hs.581355	3	RNA binding translation initiation factor activity cytoplasm translational initiation regulation of translation
201242_s_at	-0.498	11.096	-2.281	3.737e-02	0.354	-3.859	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	1	167342570	BC000006	481	1q24	Hs.291196	34	response to hypoxia sodium:potassium-exchanging ATPase activity protein binding plasma membrane sodium:potassium-exchanging ATPase complex ATP biosynthetic process ion transport potassium ion transport sodium ion transport integral to membrane basolateral plasma membrane potassium ion binding sodium ion binding	Cardiac muscle contraction
236133_x_at	0.358	2.393	2.281	3.739e-02	0.354	-3.859	ZNF254	zinc finger protein 254	19	24061815	AI983886	9534	19p12	Hs.434406	5	negative regulation of transcription from RNA polymerase II promoter DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235050_at	0.349	3.728	2.280	3.739e-02	0.354	-3.859	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12	6	-134350411	AI742872	154091	6q23.2	Hs.486508	11	transporter activity cytoplasm carbohydrate transport membrane integral to membrane substrate-specific transmembrane transporter activity perinuclear region of cytoplasm transmembrane transport
219662_at	-0.481	6.611	-2.280	3.740e-02	0.354	-3.860	C2orf49	chromosome 2 open reading frame 49	2	105320444	NM_024093	79074	2q12.1	Hs.549577	4	molecular_function cellular_component biological_process
209608_s_at	0.244	5.580	2.280	3.741e-02	0.354	-3.860	ACAT2	acetyl-Coenzyme A acetyltransferase 2	6	160102978	BC000408	39	6q25.3	Hs.571037	26	acetyl-CoA C-acetyltransferase activity protein binding cytoplasm lipid metabolic process metabolic process acyltransferase activity transferase activity	Fatty acid metabolism Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism Pyruvate metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Terpenoid backbone biosynthesis Metabolic pathways
218349_s_at	-0.310	4.154	-2.280	3.741e-02	0.354	-3.860	ZWILCH	Zwilch, kinetochore associated, homolog (Drosophila)	15	64584484	NM_017975	55055	15q22.31	Hs.21331	5	condensed chromosome kinetochore protein binding cell cycle mitosis mitotic cell cycle checkpoint cell division
237251_at	0.305	4.596	2.280	3.743e-02	0.354	-3.860	C1orf92	chromosome 1 open reading frame 92	1	155157047	AI480252	149499	1q23.1	Hs.491734	3
221865_at	-0.283	5.094	-2.280	3.743e-02	0.354	-3.860	C9orf91	chromosome 9 open reading frame 91	9	116413526	BF969986	203197	9q32	Hs.522357	9	membrane integral to membrane
216544_at	0.268	3.181	2.280	3.746e-02	0.354	-3.861	RBMY2FP	RNA binding motif protein, Y-linked, family 2, member F pseudogene	Y	22864393	AC007320	159162	Yq11.223	Hs.684794 Hs.711527	3
239307_at	0.221	4.581	2.279	3.747e-02	0.354	-3.861	MYH11	myosin, heavy chain 11, smooth muscle	16	-15704492	AA781173	4629	16p13.11	Hs.460109	33	nucleotide binding motor activity actin binding calmodulin binding ATP binding striated muscle thick filament smooth muscle contraction striated muscle contraction structural constituent of muscle myosin complex muscle thick filament assembly melanosome elastic fiber assembly cardiac muscle fiber development	Vascular smooth muscle contraction Tight junction
230560_at	0.420	5.350	2.279	3.747e-02	0.354	-3.861	STXBP6	syntaxin binding protein 6 (amisyn)	14	-24351143	N21096	29091	14q12	Hs.508958	6	cytoplasm membrane integral to membrane vesicle-mediated transport
220311_at	-0.378	4.626	-2.279	3.748e-02	0.354	-3.861	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)	21	-29166383	NM_013240	29104	21q21.3	Hs.163846	6	nucleic acid binding protein binding protein methyltransferase activity transferase activity positive regulation of cell growth methylation protein complex
226996_at	-0.374	6.769	-2.279	3.749e-02	0.354	-3.862	LCLAT1	lysocardiolipin acyltransferase 1	2	30523626, 30523640	AV717041	253558	2p23.1	Hs.468048 Hs.662770	8	1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum multicellular organismal development metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity	Tyrosine metabolism Phenylalanine metabolism Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism 1- and 2-Methylnaphthalene degradation Benzoate degradation via CoA ligation Limonene and pinene degradation Metabolic pathways
209438_at	0.438	5.146	2.279	3.749e-02	0.354	-3.862	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	AL096700	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
223297_at	-0.422	7.139	-2.279	3.751e-02	0.354	-3.862	AMMECR1L	AMME chromosomal region gene 1-like	2	-128335675	BC004208	83607	2q21	Hs.546449	3
228017_s_at	0.267	4.657	2.279	3.752e-02	0.354	-3.862	NKAIN4	Na+/K+ transporting ATPase interacting 4	20	-61342581	BF593263	128414	20q13.33	Hs.46627	7	plasma membrane integral to membrane
216537_s_at	0.301	5.164	2.279	3.753e-02	0.354	-3.863	SIGLEC7	sialic acid binding Ig-like lectin 7	19	56337369	AJ130713	27036	19q13.3	Hs.655393	20	receptor activity protein binding sugar binding integral to plasma membrane cell adhesion membrane
1554167_a_at	-0.554	7.156	-2.278	3.756e-02	0.354	-3.863	GOLGA7	golgi autoantigen, golgin subfamily a, 7	8	41467237, 41467329	BC012032	51125	8p11.21	Hs.654773	7	Golgi apparatus membrane
226905_at	0.490	7.645	2.278	3.758e-02	0.354	-3.864	FAM101B	family with sequence similarity 101, member B	17	-289998	BG036514	359845	17p13	Hs.345588 Hs.596411 Hs.719324	4
216976_s_at	-0.445	5.278	-2.277	3.762e-02	0.355	-3.865	RYK	RYK receptor-like tyrosine kinase	3	-135358667	X96588	6259	3q22	Hs.654562	13	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction axonogenesis transferase activity Wnt-protein binding Wnt receptor activity skeletal system morphogenesis
205181_at	0.337	6.308	2.277	3.764e-02	0.355	-3.865	ZNF193	zinc finger protein 193	6	28301051	NM_006299	7746	6p21.3	Hs.100921	8	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226878_at	0.304	5.212	2.277	3.765e-02	0.355	-3.866	HLA-DOA	major histocompatibility complex, class II, DO alpha	6	-33079937, -4352783, -4157999	AL581873	3111	6p21.3	Hs.631991	40	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane plasma membrane immune response integral to membrane antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II receptor activity MHC class II protein complex regulation of T cell differentiation	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
210115_at	0.413	4.086	2.277	3.766e-02	0.355	-3.866	RPL39L	ribosomal protein L39-like	3	-188321434	L05096	116832	3q27	Hs.647900	4	structural constituent of ribosome intracellular ribosome translation spermatogenesis cytosolic large ribosomal subunit
205976_at	-0.355	3.645	-2.277	3.768e-02	0.355	-3.866	FASTKD2	FAST kinase domains 2	2	207338356	NM_014929	22868	2q33.3	Hs.5930	8	protein kinase activity ATP binding apoptosis
223321_s_at	0.217	6.496	2.276	3.770e-02	0.355	-3.867	FGFRL1	fibroblast growth factor receptor-like 1	4	995609, 995759, 996251	AF312678	53834	4p16	Hs.193326	15	regulation of cell growth receptor activity fibroblast growth factor receptor activity protein binding plasma membrane negative regulation of cell proliferation integral to membrane
217985_s_at	-0.396	5.505	-2.276	3.771e-02	0.355	-3.867	BAZ1A	bromodomain adjacent to zinc finger domain, 1A	14	-34291687	AA102574	11177	14q12-q13	Hs.509140	12	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
203485_at	-0.411	5.012	-2.276	3.773e-02	0.355	-3.867	RTN1	reticulon 1	14	-59132446, -59132446, -59132446	NM_021136	6252	14q23.1	Hs.368626	23	signal transducer activity endoplasmic reticulum signal transduction membrane integral to membrane integral to endoplasmic reticulum membrane neuron differentiation
209683_at	-0.411	5.220	-2.276	3.776e-02	0.355	-3.868	FAM49A	family with sequence similarity 49, member A	2	-16597381	AA243659	81553	2p24.2	Hs.467769	8	intracellular
213870_at	0.320	5.566	2.275	3.776e-02	0.355	-3.868	COL11A2	collagen, type XI, alpha 2	6	-33262201, -33238446, -4534386, -4510632, -4340391, -4316638	AL031228	1302	6p21.3	Hs.390171	39	extracellular region collagen collagen type XI cell adhesion sensory perception of sound extracellular matrix structural constituent conferring tensile strength collagen fibril organization protein binding, bridging cartilage development soft palate development	Focal adhesion ECM-receptor interaction
244623_at	-1.305	7.440	-2.275	3.776e-02	0.355	-3.868	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5	6	73388291	BF513800	56479	6q14	Hs.445324 Hs.675919	15	inward rectifier potassium channel activity voltage-gated ion channel activity protein complex assembly ion transport potassium ion transport synaptic transmission voltage-gated potassium channel complex membrane integral to membrane potassium ion binding
236263_at	0.197	4.809	2.275	3.777e-02	0.355	-3.868	SHH	sonic hedgehog homolog (Drosophila)	7	-155288318	AI192528	6469	7q36	Hs.164537	144	patterning of blood vessels vasculogenesis metanephros development branching involved in ureteric bud morphogenesis cell fate specification neural crest cell migration neural tube formation positive regulation of neuroblast proliferation positive regulation of mesenchymal cell proliferation osteoblast development patched binding protein binding extracellular region extracellular space plasma membrane signal transduction positive regulation of hh target transcription factor activity cell-cell signaling pattern specification process axon guidance ventral midline development open tracheal system development salivary gland morphogenesis hindgut morphogenesis heart development blood coagulation androgen metabolic process peptidase activity anterior/posterior pattern formation cell surface oligodendrocyte development intein-mediated protein splicing spinal cord dorsal/ventral patterning dorsal/ventral neural tube patterning smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation positive regulation of granule cell precursor proliferation telencephalon regionalization regulation of proteolysis lung development negative regulation of cell migration male genitalia development prostate gland development regulation of epithelial cell differentiation forebrain development midbrain development hindbrain development hair follicle morphogenesis negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of T cell proliferation negative regulation of protein catabolic process positive regulation of protein import into nucleus odontogenesis of dentine-containing tooth embryonic digit morphogenesis camera-type eye development laminin-1 binding tongue morphogenesis membrane raft myoblast differentiation regulation of transcription negative regulation of cell differentiation positive regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter negative regulation of alpha-beta T cell differentiation digestive tract morphogenesis embryonic organ development developmental growth neuron fate commitment response to axon injury embryonic skeletal system development formation of anatomical boundary striated muscle cell differentiation Bergmann glial cell differentiation	Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma
210820_x_at	-0.259	6.603	-2.275	3.778e-02	0.355	-3.868	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	16	18986427	AL136647	10229	16p13.11-p12.3	Hs.157113	18	iron ion binding nucleus mitochondrion ubiquinone biosynthetic process oxidoreductase activity protein metabolic process	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
225144_at	-0.407	7.620	-2.275	3.778e-02	0.355	-3.869	BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	2	202949294	AI457436	659	2q33-q34	Hs.471119	106	nucleotide binding magnesium ion binding mesoderm formation negative regulation of systemic arterial blood pressure protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity protein binding ATP binding plasma membrane plasma membrane integral to plasma membrane caveola transcription from RNA polymerase II promoter protein amino acid phosphorylation cellular response to starvation anterior/posterior pattern formation regulation of lung blood pressure regulation of lung blood pressure transferase activity manganese ion binding positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway BMP signaling pathway BMP signaling pathway regulation of cell proliferation positive regulation of osteoblast differentiation negative regulation of vasoconstriction vascular endothelial growth factor receptor signaling pathway lung alveolus development	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
206177_s_at	0.344	3.265	2.275	3.779e-02	0.355	-3.869	ARG1	arginase, liver	6	131936057	NM_000045	383	6q23	Hs.440934	44	urea cycle arginase activity cytoplasm arginine catabolic process hydrolase activity manganese ion binding metal ion binding	Arginine and proline metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
218996_at	-0.375	6.638	-2.275	3.780e-02	0.355	-3.869	TFPT	TCF3 (E2A) fusion partner (in childhood Leukemia)	19	-59302131	NM_013342	29844	19q13	Hs.590939	9	protein binding nucleus
224203_at	0.308	5.686	2.275	3.780e-02	0.355	-3.869	SUFU	suppressor of fused homolog (Drosophila)	10	104253753	AF222345	51684	10q24.32	Hs.404089	22	skeletal system development transcription corepressor activity signal transducer activity nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent proteolysis signal transduction multicellular organismal development identical protein binding	Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma
220133_at	0.296	2.957	2.275	3.783e-02	0.355	-3.870	ODAM	odontogenic, ameloblast asssociated	4	71096832	NM_017855	54959	4q13.3	Hs.143811	11	extracellular region biomineral formation odontogenesis of dentine-containing tooth
214905_at	0.246	5.220	2.274	3.783e-02	0.355	-3.870	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	15	-77039345, -77039345	AL109674	5923	15q24.2	Hs.459035	24	Rho guanyl-nucleotide exchange factor activity protein binding intracellular cytosol plasma membrane long-term memory synaptosome growth cone neuron projection development positive regulation of Ras GTPase activity activation of Rac GTPase activity regulation of Rac protein signal transduction regulation of Rho protein signal transduction	MAPK signaling pathway Focal adhesion
217001_x_at	0.265	5.691	2.274	3.784e-02	0.355	-3.870	HLA-DOA	major histocompatibility complex, class II, DO alpha	6	-33079937, -4352783, -4157999	M29335	3111	6p21.3	Hs.631991	40	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane plasma membrane immune response integral to membrane antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II receptor activity MHC class II protein complex regulation of T cell differentiation	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
200979_at	0.867	7.231	2.274	3.785e-02	0.355	-3.870	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	X	19271931	BF739979	5160	Xp22.2-p22.1	Hs.530331	54	pyruvate dehydrogenase (acetyl-transferring) activity protein binding mitochondrion mitochondrial matrix glycolysis oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
227371_at	0.270	4.539	2.274	3.788e-02	0.355	-3.871	BAIAP2L1	BAI1-associated protein 2-like 1	7	-97758903	AA496034	55971	7q21.3-q22.1	Hs.656063 Hs.710371	13	molecular_function actin binding cellular_component signal transduction cytoskeletal adaptor activity biological_process SH3 domain binding filopodium assembly
205530_at	0.600	8.456	2.274	3.788e-02	0.355	-3.871	ETFDH	electron-transferring-flavoprotein dehydrogenase	4	159812726	NM_004453	2110	4q32-q35	Hs.155729	16	electron-transferring-flavoprotein dehydrogenase activity iron ion binding mitochondrion mitochondrial inner membrane fatty acid beta-oxidation transport response to oxidative stress electron carrier activity membrane integral to membrane oxidoreductase activity electron transport chain integral to mitochondrial inner membrane oxidoreductase activity, oxidizing metal ions with flavin as acceptor metal ion binding ubiquinone binding FAD binding 4 iron, 4 sulfur cluster binding
222126_at	0.223	5.403	2.273	3.792e-02	0.356	-3.872	AGFG2	ArfGAP with FG repeats 2	7	99974769	AI247494	3268	7q22.1	Hs.521083	9	molecular_function cellular_component ARF GTPase activator activity biological_process zinc ion binding regulation of ARF GTPase activity metal ion binding
236208_at	-0.587	6.332	-2.273	3.793e-02	0.356	-3.872	MOCS2	molybdenum cofactor synthesis 2	5	-52429651, -52429651	BE467697	4338	5q11	Hs.163645	17	cytoplasm cytosol Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor biosynthetic process sulfur metabolic process molybdopterin synthase complex molybdopterin synthase complex Mo-molybdopterin synthase activity identical protein binding
212639_x_at	-0.597	10.322	-2.273	3.793e-02	0.356	-3.872	TUBA1B	tubulin, alpha 1b	12	-47807832	AL581768	10376	12q13.12	Hs.524390 Hs.719075	42	nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization	Gap junction Pathogenic Escherichia coli infection - EHEC
214352_s_at	-0.517	6.135	-2.273	3.796e-02	0.356	-3.873	KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	12	-25249446	BF673699	3845	12p12.1	Hs.505033	430	nucleotide binding protein binding GTP binding intracellular membrane fraction plasma membrane plasma membrane endocytosis Ras protein signal transduction cell aging positive regulation of cell proliferation visual learning actin cytoskeleton organization regulation of synaptic transmission, GABAergic positive regulation of Rac protein signal transduction negative regulation of neuron apoptosis regulation of long-term neuronal synaptic plasticity striated muscle cell differentiation	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Axon guidance VEGF signaling pathway Tight junction Gap junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
224187_x_at	-0.504	11.726	-2.273	3.796e-02	0.356	-3.873	HSPA8	heat shock 70kDa protein 8	11	-122433409	AF217511	3312	11q24.1	Hs.702021	145	nucleotide binding protein binding ATP binding intracellular cytoplasm protein folding response to unfolded protein cell surface melanosome ATPase activity, coupled interspecies interaction between organisms	MAPK signaling pathway Endocytosis Antigen processing and presentation
48808_at	-0.822	6.165	-2.273	3.796e-02	0.356	-3.873	DHFR	dihydrofolate reductase	5	-79957800	AI144299	1719	5q11.2-q13.2	Hs.592364 Hs.648635	80	dihydrofolate reductase activity cellular_component glycine biosynthetic process one-carbon metabolic process nucleotide biosynthetic process oxidoreductase activity NADP or NADPH binding oxidation reduction	One carbon pool by folate Folate biosynthesis Biosynthesis of phenylpropanoids Metabolic pathways
212232_at	-0.547	8.111	-2.272	3.802e-02	0.356	-3.874	FNBP4	formin binding protein 4	11	-47694644	AB023231	23360	11p11.2	Hs.6834	11	protein binding
208480_s_at	-0.286	4.391	-2.271	3.805e-02	0.356	-3.875	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	16	-16222544, -16150922	NM_001171	368	16p13.1	Hs.442182	70	nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus	ABC transporters
225195_at	-0.498	6.934	-2.271	3.806e-02	0.356	-3.875	DPH3	DPH3, KTI11 homolog (S. cerevisiae)	3	-16273572	AI825858	285381	3p25.1	Hs.388087	8	protein binding nucleus cytoplasm zinc ion binding peptidyl-diphthamide biosynthetic process from peptidyl-histidine metal ion binding negative regulation of protein secretion positive regulation of binding
221486_at	-0.460	9.846	-2.271	3.806e-02	0.356	-3.875	ENSA	endosulfine alpha	1	-148866145, -148862377, -148862377, -148861222, -148861222	AF067170	2029	1q21.3	Hs.632456	15	receptor binding cytoplasm transport response to nutrient ion channel inhibitor activity
202158_s_at	-0.435	6.014	-2.271	3.806e-02	0.356	-3.875	CUGBP2	CUG triplet repeat, RNA binding protein 2	10	11087264, 11099898, 11246998	NM_006561	10659	10p13	Hs.309288	25	nucleotide binding RNA binding protein binding nucleus cytoplasm mRNA processing regulation of heart contraction
215646_s_at	-0.478	4.172	-2.271	3.807e-02	0.356	-3.875	VCAN	versican	5	82803248	R94644	1462	5q14.3	Hs.643801 Hs.715773	74	binding calcium ion binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development cell recognition	Cell adhesion molecules (CAMs)
242006_at	-0.313	3.691	-2.271	3.807e-02	0.356	-3.875	LCA5	Leber congenital amaurosis 5	6	-80251426, -80251426	AI379143	167691	6q14.1	Hs.21945	10	cytoplasm cytoskeleton cilium microtubule basal body protein transport cilium axoneme
210137_s_at	-0.349	7.163	-2.271	3.809e-02	0.356	-3.876	DCTD	dCMP deaminase	4	-184048237	BC001286	1635	4q35.1	Hs.183850	9	dCMP deaminase activity dCMP deaminase activity cytosol pyrimidine nucleotide metabolic process zinc ion binding nucleotide biosynthetic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds metal ion binding	Pyrimidine metabolism Metabolic pathways
228550_at	0.289	5.165	2.271	3.809e-02	0.356	-3.876	RTN4R	reticulon 4 receptor	22	-18608937	NM_023004	65078	22q11.21	Hs.30868	40	receptor activity protein binding endoplasmic reticulum plasma membrane axonogenesis anchored to membrane
218859_s_at	-0.311	7.584	-2.271	3.809e-02	0.356	-3.876	ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	20	-13642968	NM_016649	51575	20p12.1	Hs.369284	10	nucleus nucleoplasm nucleolus regulation of transcription
224443_at	0.712	6.229	2.270	3.812e-02	0.356	-3.876	C1orf97	chromosome 1 open reading frame 97	1	209622719	BC005997	84791	1q32.3	Hs.523932	4
224525_s_at	-0.756	5.580	-2.270	3.812e-02	0.356	-3.876	OLA1	Obg-like ATPase 1	2	-174645420	AL136546	29789	2q31.1	Hs.157351	11	nucleotide binding protein binding ATP binding GTP binding intracellular cytoplasm ATP catabolic process hydrolase activity
214684_at	-0.367	6.892	-2.270	3.813e-02	0.356	-3.877	MEF2A	myocyte enhancer factor 2A	15	97923655, 97990705	X63381	4205	15q26	Hs.268675	77	transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding
242851_at	0.331	5.626	2.270	3.814e-02	0.356	-3.877	KIAA1919	KIAA1919	6	111687174	BE964989	91749	6q22	Hs.400572	5	plasma membrane ion transport sodium ion transport carbohydrate transport symporter activity integral to membrane sodium ion binding
44673_at	0.235	6.216	2.270	3.817e-02	0.357	-3.878	SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	20	-3615616	N53555	6614	20p13	Hs.31869	13	protein binding sugar binding extracellular region plasma membrane inflammatory response cell-matrix adhesion integral to membrane cell-cell adhesion	Cell adhesion molecules (CAMs)
206671_at	0.294	4.500	2.270	3.818e-02	0.357	-3.878	SAG	S-antigen; retina and pineal gland (arrestin)	2	233881047	NM_000541	6295	2q37.1	Hs.32721	25	phosphoprotein phosphatase inhibitor activity calcium ion binding protein binding cell surface receptor linked signal transduction sensory perception visual perception rhodopsin mediated phototransduction rhodopsin mediated signaling pathway response to stimulus
201037_at	-0.606	6.504	-2.269	3.822e-02	0.357	-3.879	PFKP	phosphofructokinase, platelet	10	3099751	NM_002627	5214	10p15.3-p15.2	Hs.26010	24	nucleotide binding magnesium ion binding 6-phosphofructokinase activity 6-phosphofructokinase activity protein binding ATP binding cytoplasm cytosol cytosol 6-phosphofructokinase complex glycolysis kinase activity transferase activity	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Galactose metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
210746_s_at	0.188	3.885	2.269	3.823e-02	0.357	-3.879	EPB42	erythrocyte membrane protein band 4.2	15	-41276717	M30646	2038	15q15-q21	Hs.368642	34	cell morphogenesis protein-glutamine gamma-glutamyltransferase activity structural constituent of cytoskeleton protein binding ATP binding cytoplasm plasma membrane regulation of cell shape peptide cross-linking hemoglobin metabolic process cortical cytoskeleton erythrocyte maturation spleen development ion homeostasis iron ion homeostasis
200910_at	-0.304	8.930	-2.269	3.823e-02	0.357	-3.879	CCT3	chaperonin containing TCP1, subunit 3 (gamma)	1	-154545375	NM_005998	7203	1q23	Hs.491494	19	nucleotide binding ATP binding nucleus cytoplasm cytoskeleton plasma membrane protein folding unfolded protein binding
1560060_s_at	-0.377	8.207	-2.269	3.823e-02	0.357	-3.879	VPS37C	vacuolar protein sorting 37 homolog C (S. cerevisiae)	11	-60654303	BM452172	55048	11q12.2	Hs.523715	3	endosome protein transport membrane	Endocytosis
217493_x_at	0.239	6.329	2.269	3.825e-02	0.357	-3.879	NCR2	natural cytotoxicity triggering receptor 2	6	41411505	AL136967	9436	6p21.1	Hs.194721	16	transmembrane receptor activity plasma membrane integral to plasma membrane cellular defense response signal transduction	Natural killer cell mediated cytotoxicity
236223_s_at	0.192	2.430	2.268	3.827e-02	0.357	-3.880	RIT1	Ras-like without CAAX 1	1	-154134224	AL037450	6016	1q22	Hs.491234	17	nucleotide binding calmodulin binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction small GTPase mediated signal transduction
223239_at	-0.659	6.880	-2.268	3.830e-02	0.357	-3.880	C14orf129	chromosome 14 open reading frame 129	14	95915774	BC004818	51527	14q32.2	Hs.715512	7	protein binding cytoplasm
1552542_s_at	0.296	3.542	2.268	3.830e-02	0.357	-3.880	TAGAP	T-cell activation RhoGTPase activating protein	6	-159379931, -159376014	NM_138810	117289	6q25.3	Hs.529984	11	guanyl-nucleotide exchange factor activity intracellular signal transduction
214853_s_at	-0.258	8.396	-2.268	3.831e-02	0.357	-3.881	SHC1	SHC (Src homology 2 domain containing) transforming protein 1	1	-153201397, -153201397	AI091079	6464	1q21	Hs.433795	255	activation of MAPK activity transmembrane receptor protein tyrosine kinase adaptor protein activity epidermal growth factor receptor binding insulin receptor binding insulin-like growth factor receptor binding protein binding phospholipid binding cytoplasm mitochondrion cytosol plasma membrane epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor activity intracellular signaling cascade Ras protein signal transduction positive regulation of cell proliferation insulin receptor signaling pathway regulation of growth positive regulation of DNA replication Shc-EGFR complex	ErbB signaling pathway Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity Neurotrophin signaling pathway Insulin signaling pathway Glioma Chronic myeloid leukemia
200642_at	-0.294	11.065	-2.268	3.832e-02	0.357	-3.881	SOD1	superoxide dismutase 1, soluble	21	31953805	NM_000454	6647	21q22.1 21q22.11	Hs.443914	450	activation of MAPK activity response to superoxide ovarian follicle development positive regulation of cytokine production placenta development retina homeostasis myeloid cell homeostasis superoxide dismutase activity copper ion binding extracellular space nucleus cytoplasm mitochondrion mitochondrial matrix peroxisome cytosol plasma membrane double-strand break repair DNA fragmentation involved in apoptosis glutathione metabolic process cellular iron ion homeostasis anti-apoptosis spermatogenesis embryo implantation embryo implantation cell aging cell aging sensory perception of sound locomotory behavior regulation of blood pressure cell death zinc ion binding response to heat antioxidant activity oxidoreductase activity transmission of nerve impulse removal of superoxide radicals protein phosphatase 2B binding extracellular matrix cytoplasmic vesicle response to nutrient levels myelin maintenance in the peripheral nervous system dendrite cytoplasm regulation of T cell differentiation in the thymus regulation of multicellular organism growth response to drug response to hydrogen peroxide superoxide anion generation protein homodimerization activity cell soma positive regulation of apoptosis positive regulation of catalytic activity protein complex negative regulation of neuron apoptosis response to ethanol negative regulation of cholesterol biosynthetic process regulation of protein kinase activity regulation of organ growth response to copper ion muscle maintenance metal ion binding thymus development response to axon injury hydrogen peroxide biosynthetic process hydrogen peroxide biosynthetic process chaperone binding regulation of mitochondrial membrane potential oxidation reduction heart contraction neurofilament cytoskeleton organization relaxation of vascular smooth muscle auditory receptor cell stereocilium organization	Amyotrophic lateral sclerosis (ALS) Huntington's disease Prion diseases
204717_s_at	-0.542	7.635	-2.268	3.833e-02	0.357	-3.881	SLC29A2	solute carrier family 29 (nucleoside transporters), member 2	11	-65886567	AF034102	3177	11q13	Hs.569017	26	nucleoside transmembrane transporter activity nucleus nucleolus plasma membrane integral to plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transport cell proliferation nucleoside transport
218429_s_at	0.347	6.713	2.268	3.833e-02	0.357	-3.881	C19orf66	chromosome 19 open reading frame 66	19	10057805	NM_018381	55337	19p13.2	Hs.655613	2
207996_s_at	-0.712	6.652	-2.267	3.835e-02	0.357	-3.882	C18orf1	chromosome 18 open reading frame 1	18	13208785, 13601664, 13610866	NM_004338	753	18p11.2	Hs.149363	9	molecular_function plasma membrane biological_process integral to membrane
225161_at	-0.409	7.141	-2.267	3.837e-02	0.357	-3.882	GFM1	G elongation factor, mitochondrial 1	3	159845010	AI659020	85476	3q25.1-q26.2	Hs.518355	11	nucleotide binding translation elongation factor activity GTPase activity GTP binding intracellular mitochondrion translational elongation
228254_at	-0.268	6.186	-2.267	3.837e-02	0.357	-3.882	STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	2	-152681560	AW024643	10254	2q23.3	Hs.17200	32	protein binding cytoplasm endosome cytosol intracellular protein transport membrane	Endocytosis Jak-STAT signaling pathway
235780_at	0.379	3.224	2.267	3.837e-02	0.357	-3.882	PRKACB	protein kinase, cAMP-dependent, catalytic, beta	1	84316332, 84316332, 84382539	BE622723	5567	1p36.1	Hs.487325	38	nucleotide binding magnesium ion binding protein serine/threonine kinase activity cAMP-dependent protein kinase activity ATP binding nucleus cytoplasm cAMP-dependent protein kinase complex protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger protein kinase cascade hormone-mediated signaling transferase activity	MAPK signaling pathway Calcium signaling pathway Chemokine signaling pathway Apoptosis Vascular smooth muscle contraction Wnt signaling pathway Hedgehog signaling pathway Gap junction Long-term potentiation Olfactory transduction Taste transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Vibrio cholerae infection
223155_at	-0.444	8.022	-2.267	3.838e-02	0.357	-3.882	HDHD2	haloacid dehalogenase-like hydrolase domain containing 2	18	-42887778	AL136681	84064	18q21.1	Hs.465041	8	metabolic process hydrolase activity
230842_at	0.223	6.564	2.267	3.841e-02	0.357	-3.883	FGFR2	fibroblast growth factor receptor 2	10	-123231358, -123231358, -123227834, -123227834, -123227834, -123227834, -123227833	AI807481	2263	10q26	Hs.533683	232	nucleotide binding receptor activity fibroblast growth factor receptor activity protein binding ATP binding extracellular region plasma membrane plasma membrane protein amino acid phosphorylation heparin binding fibroblast growth factor receptor signaling pathway cell surface integral to membrane cell growth transferase activity	MAPK signaling pathway Endocytosis Regulation of actin cytoskeleton Pathways in cancer Prostate cancer
225296_at	-0.372	5.591	-2.267	3.841e-02	0.357	-3.883	ZNF317	zinc finger protein 317	19	9112085	AB046808	57693		Hs.465829	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211505_s_at	-0.333	7.395	-2.267	3.841e-02	0.357	-3.883	STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	20	-47163282	AL136601	6780	20q13.1	Hs.596704	26	double-stranded RNA binding protein binding intracellular rough endoplasmic reticulum microtubule associated complex intracellular mRNA localization ribonucleoprotein complex
221449_s_at	-0.660	8.152	-2.266	3.844e-02	0.357	-3.884	ITFG1	integrin alpha FG-GAP repeat containing 1	16	-45746798	NM_030790	81533	16q12.1	Hs.42217	5	protein binding extracellular region membrane integral to membrane
215649_s_at	0.291	4.967	2.266	3.845e-02	0.358	-3.884	MVK	mevalonate kinase	12	108495882	AF217536	4598	12q24	Hs.130607	42	nucleotide binding mevalonate kinase activity ATP binding cytoplasm peroxisome cholesterol biosynthetic process metabolic process isoprenoid biosynthetic process phosphorylation transferase activity identical protein binding	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
219228_at	0.343	6.382	2.266	3.846e-02	0.358	-3.884	ZNF331	zinc finger protein 331	19	58715988, 58733144, 58750372	NM_018555	55422	19q13.42	Hs.185674	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
232698_at	0.284	5.055	2.266	3.848e-02	0.358	-3.884	BPIL1	bactericidal/permeability-increasing protein-like 1	20	31059067	AK027068	80341	20q11.21	Hs.257045	10	extracellular region lipid binding
226212_s_at	-0.468	6.099	-2.266	3.848e-02	0.358	-3.885	INSR	insulin receptor	19	-7063265	AV726689	3643	19p13.3-p13.2	Hs.465744	351	nucleotide binding activation of MAPK activity positive regulation of protein amino acid phosphorylation heart morphogenesis receptor signaling protein tyrosine kinase activity receptor activity insulin receptor activity insulin-like growth factor receptor binding ATP binding GTP binding endosome microsome cytosol plasma membrane plasma membrane insulin receptor complex caveola carbohydrate metabolic process G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation positive regulation of cell proliferation insulin receptor signaling pathway endosome membrane transferase activity peptidyl-tyrosine phosphorylation transformation of host cell by virus protein phosphatase binding male sex determination positive regulation of cell migration insulin-like growth factor I binding insulin-like growth factor II binding activation of protein kinase B activity regulation of gene-specific transcription SH2 domain binding glucose homeostasis positive regulation of MAPKKK cascade 3-phosphoinositide-dependent protein kinase binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of nitric oxide biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of DNA replication positive regulation of glycolysis positive regulation of mitosis regulation of embryonic development positive regulation of glucose import positive regulation of glucose import protein amino acid autophosphorylation positive regulation of developmental growth protein heterotetramerization PTB domain binding positive regulation of protein kinase B signaling cascade positive regulation of respiratory burst	Adherens junction Insulin signaling pathway Type II diabetes mellitus
222671_s_at	-0.306	5.483	-2.266	3.849e-02	0.358	-3.885	JMJD4	jumonji domain containing 4	1	-225985513	AA582199	65094	1q42.13	Hs.325081 Hs.555974	2
214292_at	0.307	4.306	2.265	3.850e-02	0.358	-3.885	ITGB4	integrin, beta 4	17	71229110, 71232370	AA808063	3691	17q25	Hs.632226	120	receptor activity protein binding cell communication cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
223319_at	-0.332	7.040	-2.265	3.852e-02	0.358	-3.885	GPHN	gephyrin	14	66043877	AF272663	10243	14q23.3	Hs.208765	29	nucleotide binding magnesium ion binding catalytic activity protein binding intracellular cytoplasm cytoskeleton plasma membrane Mo-molybdopterin cofactor biosynthetic process establishment of synaptic specificity at neuromuscular junction cell junction synapse postsynaptic membrane
206536_s_at	-0.315	4.250	-2.265	3.853e-02	0.358	-3.886	XIAP	X-linked inhibitor of apoptosis	X	122821728	U32974	331	Xq25	Hs.356076	170	protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding	Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer
202336_s_at	-0.458	10.263	-2.265	3.855e-02	0.358	-3.886	PAM	peptidylglycine alpha-amidating monooxygenase	5	102229425	NM_000919	5066	5q14-q21	Hs.369430	34	monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding protein binding extracellular region protein modification process peptide metabolic process zinc ion binding cellular process membrane integral to membrane lyase activity secretory granule L-ascorbic acid binding metal ion binding oxidation reduction
1552524_at	0.368	5.967	2.264	3.858e-02	0.358	-3.887	ART5	ADP-ribosyltransferase 5	11	-3616311, -3616311	NM_053017	116969	11p15.4	Hs.125680	6	NAD(P)+-protein-arginine ADP-ribosyltransferase activity extracellular region protein amino acid ADP-ribosylation transferase activity, transferring glycosyl groups
202001_s_at	0.231	11.523	2.264	3.860e-02	0.358	-3.887	NDUFA6	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa	22	-40811475	NM_002490	4700	22q13.2-q13.31	Hs.274416	15	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport response to oxidative stress NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1565947_a_at	0.259	3.298	2.264	3.862e-02	0.358	-3.888	CHML	choroideremia-like (Rab escort protein 2)	1	-239858789	AJ293392	1122	1q42-qter	Hs.654545	17	Rab geranylgeranyltransferase activity GTPase activator activity Rab-protein geranylgeranyltransferase complex intracellular protein transport visual perception regulation of GTPase activity
228697_at	-0.437	9.162	-2.263	3.866e-02	0.358	-3.889	HINT3	histidine triad nucleotide binding protein 3	6	126319553	AW731710	135114	6q22.32	Hs.72325	6	nucleus cytoplasm hydrolase activity
201513_at	-0.488	6.391	-2.263	3.867e-02	0.359	-3.889	TSN	translin	2	122229590	AI659180	7247	2q21.1	Hs.75066	28	nucleus cytoplasm DNA recombination sequence-specific DNA binding
231742_at	0.284	4.236	2.263	3.868e-02	0.359	-3.889	CRX	cone-rod homeobox	19	53016910	NM_000554	1406	19q13.3	Hs.617342 Hs.633434 Hs.639114	31	chromatin binding transcription factor activity protein binding nucleus transcription factor complex regulation of transcription, DNA-dependent visual perception circadian rhythm organ morphogenesis transcription activator activity sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter positive regulation of photoreceptor cell differentiation response to stimulus
205052_at	0.391	8.373	2.263	3.871e-02	0.359	-3.890	AUH	AU RNA binding protein/enoyl-Coenzyme A hydratase	9	-93015917	NM_001698	549	9q22.31	Hs.175905	16	RNA binding mRNA 3'-UTR binding enoyl-CoA hydratase activity methylglutaconyl-CoA hydratase activity mitochondrion mRNA catabolic process metabolic process branched chain family amino acid catabolic process lyase activity	Valine, leucine and isoleucine degradation Metabolic pathways
1555421_at	0.227	2.075	2.262	3.872e-02	0.359	-3.890	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	2	-224328290	BC009606	130340	2q36.1	Hs.632555	13	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane membrane coat clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
210844_x_at	-0.333	8.424	-2.262	3.876e-02	0.359	-3.891	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	5	138117005	D14705	1495	5q31	Hs.534797 Hs.656653	70	structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding	Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1558862_at	0.221	3.872	2.262	3.876e-02	0.359	-3.891	NBPF5	neuroblastoma breakpoint family, member 5	1		BC043522	284610	1p13.3	Hs.512038	2	cytoplasm
210813_s_at	-0.393	3.200	-2.262	3.877e-02	0.359	-3.891	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	5	82409072	BC005259	7518	5q13-q14	Hs.567359	93	condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding nucleus nucleus cytosol DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development protein C-terminus binding response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA repair positive regulation of ligase activity	Non-homologous end-joining
210605_s_at	-0.276	6.486	-2.262	3.878e-02	0.359	-3.891	MFGE8	milk fat globule-EGF factor 8 protein	15	-87242917	BC003610	4240	15q25	Hs.3745	36	phosphatidylserine binding integrin binding protein binding extracellular space cytoplasm phagocytosis, recognition phagocytosis, engulfment cell adhesion single fertilization phosphatidylethanolamine binding external side of plasma membrane membrane extrinsic to plasma membrane interspecies interaction between organisms positive regulation of phagocytosis
229246_at	0.383	6.236	2.262	3.878e-02	0.359	-3.891	FLJ44342	hypothetical LOC645460	17		AI803504	645460	17q22	Hs.68714 Hs.710026	1
201323_at	-0.397	6.712	-2.261	3.880e-02	0.359	-3.892	EBNA1BP2	EBNA1 binding protein 2	1	-43402432, -43402432	NM_006824	10969	1p35-p33	Hs.346868	20	protein binding membrane fraction nucleus nucleolus ribosome biogenesis
241370_at	-0.471	7.686	-2.261	3.882e-02	0.359	-3.892	LOC286052	hypothetical protein LOC286052	8		AA278233	286052	8q24.13	Hs.100691	1
1562736_at	0.326	3.089	2.261	3.883e-02	0.359	-3.892	LHX9	LIM homeobox 9	1	196148257, 196153139	AJ277914	56956	1q31-q32	Hs.442578 Hs.706475	6	transcription factor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
209062_x_at	-0.286	6.375	-2.261	3.884e-02	0.359	-3.893	NCOA3	nuclear receptor coactivator 3	20	45564063	AF010227	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
1558517_s_at	0.330	4.471	2.261	3.885e-02	0.359	-3.893	LRRC8C	leucine rich repeat containing 8 family, member C	1	89871231	CA773938	84230	1p22.2	Hs.412836	6	protein binding membrane integral to membrane
225421_at	-0.612	8.529	-2.261	3.886e-02	0.359	-3.893	PM20D2	peptidase M20 domain containing 2	6	89912487	AI654133	135293	6q15	Hs.709364	2	proteolysis metallopeptidase activity hydrolase activity protein dimerization activity
230804_at	-0.407	2.494	-2.260	3.887e-02	0.359	-3.893	NKAPL	NFKB activating protein-like	6	28335076	AA902654	222698	6p22.1	Hs.239181	3
220806_x_at	0.391	3.848	2.260	3.888e-02	0.359	-3.893	GNG13	guanine nucleotide binding protein (G protein), gamma 13	16	-788041	NM_016541	51764	16p13.3	Hs.247888	13	GTPase activity signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger hormone-mediated signaling sensory perception of taste	Chemokine signaling pathway Taste transduction
215073_s_at	0.356	5.897	2.260	3.890e-02	0.359	-3.894	NR2F2	nuclear receptor subfamily 2, group F, member 2	15	94670160, 94675114, 94676797, 94677572	AL554245	7026	15q26	Hs.657455	27	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding
238886_at	0.282	4.886	2.260	3.890e-02	0.359	-3.894	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	14	-74667923	BF056141	10972	14q24.3	Hs.74137	22	protein binding microsome ER-Golgi intermediate compartment Golgi apparatus cis-Golgi network protein transport membrane integral to membrane vesicle-mediated transport melanosome zymogen granule membrane regulated secretory pathway vesicle targeting, to, from or within Golgi
1559449_a_at	-0.335	4.646	-2.260	3.891e-02	0.359	-3.894	ZNF254	zinc finger protein 254	19	24061815	BF679633	9534	19p12	Hs.434406	5	negative regulation of transcription from RNA polymerase II promoter DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1570173_at	-0.258	2.342	-2.260	3.891e-02	0.359	-3.894	INTS7	integrator complex subunit 7	1	-210181320	BC036009	25896	1p36.13-q42.3	Hs.369285	8	protein binding nucleus snRNA processing integrator complex
224299_x_at	0.264	5.439	2.260	3.892e-02	0.359	-3.895	FTCD	formiminotransferase cyclodeaminase	21	-46381121, -46380603	AF289023	10841	21q22.3	Hs.415846	11	folic acid binding cytoplasm Golgi apparatus histidine metabolic process folic acid and derivative metabolic process transferase activity lyase activity glutamate formimidoyltransferase activity formimidoyltetrahydrofolate cyclodeaminase activity cellular metabolic process	Histidine metabolism One carbon pool by folate Metabolic pathways
239582_at	0.218	4.301	2.260	3.893e-02	0.359	-3.895	PML	promyelocytic leukemia	15	72074066, 72074066, 72074066	AW514654	5371	15q22	Hs.526464	208	response to hypoxia DNA binding intracellular insoluble fraction nucleus nucleoplasm nucleolus cytoplasm protein complex assembly induction of apoptosis activation of caspase activity DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest cell cycle arrest transforming growth factor beta receptor signaling pathway common-partner SMAD protein phosphorylation SMAD protein nuclear translocation cell aging zinc ion binding negative regulation of cell proliferation response to UV response to gamma radiation nuclear matrix negative regulation of transcription negative regulation of angiogenesis PML body myeloid cell differentiation negative regulation of cell growth transcription regulator activity PML body organization ubiquitin protein ligase binding nuclear membrane response to cytokine stimulus DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis protein homodimerization activity interspecies interaction between organisms regulation of MHC class I biosynthetic process SMAD binding metal ion binding retinoic acid receptor signaling pathway maintenance of protein location in nucleus	Ubiquitin mediated proteolysis Pathways in cancer Acute myeloid leukemia
214464_at	-0.466	7.215	-2.259	3.895e-02	0.359	-3.895	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	1	-225244188	NM_003607	8476	1q42.11	Hs.35433	20	nucleotide binding magnesium ion binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cytoplasm cell-cell junction protein amino acid phosphorylation intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding cell leading edge actin cytoskeleton reorganization identical protein binding
228363_at	-0.248	8.575	-2.259	3.895e-02	0.359	-3.895	XIAP	X-linked inhibitor of apoptosis	X	122821728	BF109251	331	Xq25	Hs.356076	170	protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding	Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer
219397_at	-0.408	6.397	-2.259	3.896e-02	0.359	-3.895	COQ10B	coenzyme Q10 homolog B (S. cerevisiae)	2	198026475	NM_025147	80219	2q33.1	Hs.715692	3	mitochondrion
242900_at	-0.518	4.652	-2.259	3.897e-02	0.359	-3.896	ALG10B	asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast)	12	36996823	BF244214	144245	12q12	Hs.259305	5	plasma membrane integral to membrane transferase activity, transferring hexosyl groups	N-Glycan biosynthesis Metabolic pathways
204809_at	-0.380	7.354	-2.259	3.901e-02	0.360	-3.897	CLPX	ClpX caseinolytic peptidase X homolog (E. coli)	15	-63229836	NM_006660	10845	15q22.2-q22.3	Hs.113823	8	nucleotide binding ATP-dependent peptidase activity ATP binding mitochondrion mitochondrion mitochondrial inner membrane protein folding zinc ion binding mitochondrial endopeptidase Clp complex protein transport peptidase activator activity ATPase activity mitochondrial nucleoid metal ion binding unfolded protein binding proteolysis involved in cellular protein catabolic process
235504_at	-0.493	4.434	-2.258	3.903e-02	0.360	-3.897	GREM2	gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)	1	-238719495	BE786990	64388	1q43	Hs.98206	9	cytokine activity extracellular region extracellular region extracellular space BMP signaling pathway
213670_x_at	-0.311	6.786	-2.258	3.906e-02	0.360	-3.898	NSUN5B	NOL1/NOP2/Sun domain family, member 5B	7	74877581	AI768378	155400	7q11.23	Hs.436034	5
37005_at	0.270	7.230	2.258	3.907e-02	0.360	-3.898	NBL1	neuroblastoma, suppression of tumorigenicity 1	1	19842312, 19843394	D28124	4681	1p36.13	Hs.654502	18	extracellular region
202026_at	0.233	11.155	2.258	3.908e-02	0.360	-3.898	SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein	11	111462780	NM_003002	6392	11q23	Hs.356270 Hs.719164	69	succinate dehydrogenase activity mitochondrion mitochondrial envelope mitochondrial inner membrane mitochondrial inner membrane tricarboxylic acid cycle transport electron carrier activity membrane integral to membrane heme binding electron transport chain metal ion binding	Citrate cycle (TCA cycle) Oxidative phosphorylation Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
224740_at	-0.456	6.749	-2.258	3.908e-02	0.360	-3.898	C5orf43	chromosome 5 open reading frame 43	5	-60489292	BE613001	643155	5q12.1	Hs.508479	2	membrane integral to membrane
1558934_a_at	0.321	3.396	2.257	3.912e-02	0.360	-3.899	GTF2H5	general transcription factor IIH, polypeptide 5	6	158509366	AL134162	404672	6q25.3	Hs.356224	11	DNA binding nucleus nucleotide-excision repair response to DNA damage stimulus regulation of transcription	Nucleotide excision repair
1565641_at	0.246	6.829	2.257	3.915e-02	0.360	-3.900	C16orf45	chromosome 16 open reading frame 45	16	15435825, 15503623	BE503823	89927	16p13.11	Hs.401798	5	protein binding
226279_at	-0.880	6.872	-2.257	3.915e-02	0.360	-3.900	PRSS23	protease, serine, 23	11	86189138	AW471145	11098	11q14.1	Hs.25338	13	serine-type endopeptidase activity extracellular region nucleus proteolysis peptidase activity
201963_at	0.510	11.160	2.256	3.917e-02	0.360	-3.900	ACSL1	acyl-CoA synthetase long-chain family member 1	4	-185913742	NM_021122	2180	4q34-q35	Hs.406678	20	nucleotide binding magnesium ion binding long-chain-fatty-acid-CoA ligase activity long-chain-fatty-acid-CoA ligase activity ATP binding mitochondrion mitochondrial outer membrane peroxisome peroxisomal membrane endoplasmic reticulum microsome cytosol lipid metabolic process fatty acid metabolic process digestion metabolic process membrane integral to membrane ligase activity regulation of fatty acid oxidation	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
204051_s_at	-0.900	5.763	-2.256	3.919e-02	0.360	-3.901	SFRP4	secreted frizzled-related protein 4	7	-37912059	AW089415	6424	7p14.1	Hs.658169	27	protein binding extracellular region extracellular space signal transduction embryo implantation Wnt receptor signaling pathway cell differentiation	Wnt signaling pathway
219507_at	-0.349	5.449	-2.256	3.921e-02	0.360	-3.901	RSRC1	arginine/serine-rich coiled-coil 1	3	159310585	NM_016625	51319	3q25.32	Hs.591283	5	alternative nuclear mRNA splicing, via spliceosome protein binding nucleus protein amino acid phosphorylation nucleocytoplasmic transport RNA splicing nuclear speck response to antibiotic
206268_at	0.250	4.319	2.256	3.922e-02	0.360	-3.901	LEFTY1	left-right determination factor 1	1	-224140604	NM_020997	10637	1q42.1	Hs.656214	11	cytokine activity transforming growth factor beta receptor binding extracellular region extracellular space transforming growth factor beta receptor signaling pathway multicellular organismal development growth factor activity cell growth	TGF-beta signaling pathway
231860_at	-0.347	5.417	-2.256	3.922e-02	0.360	-3.901	BRWD1	bromodomain and WD repeat domain containing 1	21	-39590234, -39484017, -39479273	AW268572	54014	21q22.2	Hs.654740	8	protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter biological_process transcription regulator activity regulation of transcription
236837_x_at	0.376	3.180	2.256	3.924e-02	0.360	-3.902	LOC650794	similar to FRAS1 related extracellular matrix protein 2	13		BE669806	650794	13q12.11	Hs.147563
210295_at	0.192	4.509	2.256	3.924e-02	0.360	-3.902	MAGEA10	melanoma antigen family A, 10	X	-151053563	BC004105	4109	Xq28	Hs.18048	6
222015_at	0.245	6.356	2.255	3.925e-02	0.360	-3.902	CSNK1E	casein kinase 1, epsilon	22	-37016642, -37016642	AW192876	1454	22q13.1	Hs.474833	65	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm DNA repair protein amino acid phosphorylation signal transduction transferase activity	Wnt signaling pathway Hedgehog signaling pathway Circadian rhythm - mammal
214907_at	0.481	4.284	2.255	3.925e-02	0.360	-3.902	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	19	46774370	BF110434	90273	19q13.2	Hs.655885	3	membrane integral to membrane
1553465_a_at	0.344	3.698	2.255	3.926e-02	0.360	-3.902	CES7	carboxylesterase 7	16	-54437566	NM_145024	221223	16q12.2	Hs.350800	4	carboxylesterase activity extracellular region hydrolase activity	Tropane, piperidine and pyridine alkaloid biosynthesis Drug metabolism - other enzymes
1554017_at	0.238	5.011	2.255	3.928e-02	0.360	-3.902	RILPL1	Rab interacting lysosomal protein-like 1	12	-122521861	BC020829	353116	12q24.31	Hs.530315	3	cytoplasm cytosol
221602_s_at	0.453	5.142	2.255	3.929e-02	0.360	-3.903	FAIM3	Fas apoptotic inhibitory molecule 3	1	-205143252, -205143252	AF057557	9214	1q32.1	Hs.58831 Hs.719320	10	nucleus cytoplasm plasma membrane focal adhesion anti-apoptosis immune response cellular defense response integral to membrane
226469_s_at	-0.740	5.475	-2.255	3.929e-02	0.360	-3.903	GGT7	gamma-glutamyltransferase 7	20	-32896183	AL049709	2686	20q11.22	Hs.433738	9	gamma-glutamyltransferase activity glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity	Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways
212066_s_at	-0.281	8.025	-2.255	3.929e-02	0.360	-3.903	USP34	ubiquitin specific peptidase 34	2	-61268093	AB018272	9736	2p15	Hs.644708	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
1557984_s_at	-0.785	4.624	-2.255	3.929e-02	0.360	-3.903	RPAP3	RNA polymerase II associated protein 3	12	-46341982	BI464019	79657	12q13.11	Hs.437855	6	binding
220525_s_at	-0.310	7.576	-2.255	3.930e-02	0.360	-3.903	AUP1	ancient ubiquitous protein 1	2	-74607282	NM_012103	550	2p13	Hs.411480	10	protein binding endoplasmic reticulum membrane integral to membrane modification-dependent protein catabolic process
229397_s_at	-0.308	5.776	-2.255	3.931e-02	0.360	-3.903	GRLF1	glucocorticoid receptor DNA binding factor 1	19	52113772	AI275597	2909	19q13.3	Hs.509447	26	DNA binding transcription corepressor activity GTPase activator activity intracellular nucleus cytoplasm signal transduction negative regulation of transcription	Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
64440_at	0.316	7.376	2.255	3.931e-02	0.360	-3.903	IL17RC	interleukin 17 receptor C	3	9933763	AI560217	84818	3p25.3 3p25.3-p24.1	Hs.129959	14	receptor activity plasma membrane integral to membrane
233644_at	0.296	2.681	2.255	3.931e-02	0.360	-3.903	KATNAL2	katanin p60 subunit A-like 2	18	42780784	AL512748	83473	18q21.1	Hs.404137 Hs.660213	3	nucleotide binding ATP binding microtubule microtubule-severing ATPase activity hydrolase activity nucleoside-triphosphatase activity
218740_s_at	0.274	7.660	2.255	3.931e-02	0.360	-3.903	CDK5RAP3	CDK5 regulatory subunit associated protein 3	17	43403427	NM_025197	80279	17q21.32	Hs.20157	21	regulation of cyclin-dependent protein kinase activity protein binding cellular_component brain development neuronal Cdc2-like kinase binding regulation of neuron differentiation
227201_at	-0.435	6.553	-2.255	3.931e-02	0.360	-3.903	LOC643837	hypothetical LOC643837	1	752926	AI679230	643837	1p36.33	Hs.133183	2
218611_at	-0.809	7.569	-2.254	3.932e-02	0.360	-3.903	IER5	immediate early response 5	1	179324260	NM_016545	51278	1q25.3	Hs.716489	8
229521_at	0.307	5.344	2.254	3.933e-02	0.360	-3.904	FLJ36031	hypothetical protein FLJ36031	7	-106086384	BE466274	168455	7q22.3	Hs.29692	5
221121_at	0.231	4.718	2.254	3.934e-02	0.360	-3.904	CXorf48	chromosome X open reading frame 48	X	-134118128, -134118126	NM_017863	54967	Xq26.3	Hs.272804	4
224001_at	0.298	5.706	2.254	3.935e-02	0.360	-3.904	FAM135B	family with sequence similarity 135, member B	8	-139211447	AF131744	51059	8q24.23	Hs.126024	5
226907_at	-0.855	7.905	-2.254	3.935e-02	0.360	-3.904	PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C	6	150505880	N32557	81706	6q24.3-q25.3	Hs.486798	10	protein serine/threonine phosphatase inhibitor activity protein binding cytoplasm membrane regulation of phosphorylation
220110_s_at	0.324	3.560	2.254	3.938e-02	0.360	-3.905	NXF3	nuclear RNA export factor 3	X	-102217405	NM_022052	56000	Xq22-q23	Hs.60386	7	nucleotide binding mRNA binding protein binding intracellular nucleus cytoplasm transport poly(A)+ mRNA export from nucleus nuclear RNA export factor complex
205247_at	0.383	6.980	2.254	3.938e-02	0.360	-3.905	NOTCH4	Notch homolog 4 (Drosophila)	6	-32270597, -3569804, -3377584	AI743713	4855	6p21.3	Hs.436100	70	patterning of blood vessels cell fate determination morphogenesis of a branching structure calcium ion binding protein binding extracellular space nucleus plasma membrane integral to plasma membrane Notch signaling pathway JAK-STAT cascade nervous system development brain development aging embryonic development basal plasma membrane cell surface hemopoiesis mammary gland development regulation of transcription negative regulation of endothelial cell differentiation positive regulation of transcription, DNA-dependent protein heterodimerization activity positive regulation of smooth muscle cell proliferation advanced glycation end-product receptor activity regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
209393_s_at	-0.481	7.771	-2.254	3.939e-02	0.360	-3.905	EIF4E2	eukaryotic translation initiation factor 4E family member 2	2	233123600	AF047695	9470	2q37.1	Hs.292026 Hs.700929	15	RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation	mTOR signaling pathway Insulin signaling pathway
214261_s_at	0.349	3.938	2.253	3.940e-02	0.360	-3.905	ADH6	alcohol dehydrogenase 6 (class V)	4	-100344901, -100342817	H71135	130	4q23	Hs.586161	13	alcohol dehydrogenase activity, zinc-dependent binding cellular_component cytoplasm cytosol ethanol oxidation zinc ion binding electron carrier activity oxidoreductase activity response to ethanol metal ion binding oxidation reduction	Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
218567_x_at	-0.343	6.024	-2.253	3.940e-02	0.360	-3.905	DPP3	dipeptidyl-peptidase 3	11	66004455	NM_005700	10072	11q12-q13.1	Hs.502914	29	aminopeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity dipeptidyl-peptidase activity zinc ion binding metal ion binding
205993_s_at	0.228	5.742	2.253	3.941e-02	0.360	-3.905	TBX2	T-box 2	17	56832038	NM_005994	6909	17q23	Hs.531085	25	negative regulation of transcription from RNA polymerase II promoter heart morphogenesis transcription factor activity protein binding nucleus transcription factor complex multicellular organismal development muscle cell fate determination cell aging positive regulation of cell proliferation transcription repressor activity mammary gland development sequence-specific DNA binding cardiac muscle tissue development
204350_s_at	-0.300	7.296	-2.253	3.941e-02	0.360	-3.905	MED7	mediator complex subunit 7	5	-156498028, -156498028	NM_004270	9443	5q33.3	Hs.279902 Hs.719330	15	transcription coactivator activity protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription regulator activity regulation of transcription
219363_s_at	0.349	8.548	2.253	3.942e-02	0.360	-3.906	MTERFD1	MTERF domain containing 1	8	-97320820	NM_015942	51001	8q22.1	Hs.308613	5	nucleus mitochondrion
216587_s_at	0.302	3.795	2.253	3.942e-02	0.360	-3.906	FZD8	frizzled homolog 8 (Drosophila)	10	-35967182	AL121749	8325	10p11.21	Hs.302634	14	non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity G-protein coupled receptor protein signaling pathway multicellular organismal development membrane integral to membrane Wnt receptor signaling pathway Wnt-protein binding Wnt receptor activity	Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma
1558523_at	0.259	2.859	2.253	3.944e-02	0.360	-3.906	FAM184A	family with sequence similarity 184, member A	6	-119322694, -119322694	AJ420563	79632	6q22.31	Hs.443789	5
227612_at	0.240	3.583	2.253	3.944e-02	0.360	-3.906	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	19	-11423142	R20763	1995	19p13.2	Hs.1701	8	nucleotide binding RNA binding multicellular organismal development nervous system development cell differentiation
214900_at	0.187	5.485	2.253	3.946e-02	0.360	-3.906	ZKSCAN1	zinc finger with KRAB and SCAN domains 1	7	99451154	AC004522	7586	7q21.3-q22.1	Hs.615360	11	transcription factor activity intracellular nucleus cytoplasm mitochondrion regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203848_at	-0.356	6.645	-2.253	3.946e-02	0.360	-3.906	AKAP8	A kinase (PRKA) anchor protein 8	19	-15325334	AL050160	10270	19p13.1	Hs.719292	18	condensed chromosome female pronucleus DNA binding intracellular nucleus nucleolus mitosis mitotic chromosome condensation signal transduction zinc ion binding nuclear matrix protein kinase binding metal ion binding
220805_at	0.277	5.648	2.253	3.946e-02	0.360	-3.907	HRH2	histamine receptor H2	5	175017645, 175041069	NM_022304	3274	5q35.2	Hs.247885 Hs.716212	41	receptor activity G-protein coupled receptor activity histamine receptor activity plasma membrane integral to plasma membrane immune response signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger	Calcium signaling pathway Neuroactive ligand-receptor interaction
201178_at	-0.289	7.494	-2.252	3.953e-02	0.361	-3.908	FBXO7	F-box protein 7	22	31200706, 31201223	NM_012179	25793	22q12-q13	Hs.5912	19	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding ubiquitin-dependent protein catabolic process regulation of protein stability
200880_at	-0.459	7.305	-2.252	3.953e-02	0.361	-3.908	DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	9	33015208	AL534104	3301	9p13-p12	Hs.445203 Hs.707338	27	protein folding response to unfolded protein spermatogenesis zinc ion binding membrane sperm motility androgen receptor signaling pathway heat shock protein binding metal ion binding low-density lipoprotein receptor binding unfolded protein binding
201295_s_at	-0.750	4.703	-2.252	3.954e-02	0.361	-3.908	WSB1	WD repeat and SOCS box-containing 1	17	22645232	BF111821	26118	17q11.1	Hs.446017	21	molecular_function protein binding cellular_component intracellular intracellular signaling cascade biological_process modification-dependent protein catabolic process
243570_at	0.392	4.003	2.251	3.956e-02	0.361	-3.909	SPCS2	signal peptidase complex subunit 2 homolog (S. cerevisiae)	11	74337939	AA921960	9789	11q13.4	Hs.282700 Hs.705711	4	endoplasmic reticulum signal peptidase complex microsome signal peptide processing peptidase activity membrane integral to membrane
235747_at	-0.440	6.792	-2.251	3.957e-02	0.361	-3.909	SLC25A16	solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16	10	-69912102	AI305170	8034	10q21.3	Hs.180408	6	binding mitochondrion mitochondrial inner membrane transport solute:solute antiporter activity membrane integral to membrane
225262_at	-0.441	6.462	-2.250	3.963e-02	0.361	-3.910	FOSL2	FOS-like antigen 2	2	28469282	AI670862	2355	2p23.3	Hs.220971 Hs.596972	20	transcription factor activity nucleus nucleolus regulation of transcription from RNA polymerase II promoter cell death sequence-specific DNA binding protein dimerization activity positive regulation of fibroblast proliferation
213988_s_at	-0.413	5.980	-2.250	3.963e-02	0.361	-3.910	SAT1	spermidine/spermine N1-acetyltransferase 1	X	23711195	BE971383	6303	Xp22.1	Hs.28491	46	diamine N-acetyltransferase activity protein binding intracellular cytoplasm metabolic process acyltransferase activity transferase activity	Arginine and proline metabolism Metabolic pathways
209847_at	0.479	4.730	2.250	3.963e-02	0.361	-3.910	CDH17	cadherin 17, LI cadherin (liver-intestine)	8	-95208569, -95208569	U07969	1015	8q22.1	Hs.591853	20	transporter activity proton-dependent oligopeptide secondary active transmembrane transporter activity calcium ion binding protein binding plasma membrane transport oligopeptide transport cell adhesion homophilic cell adhesion integral to membrane basolateral plasma membrane calcium-dependent cell-cell adhesion
210935_s_at	-0.303	4.435	-2.250	3.963e-02	0.361	-3.910	WDR1	WD repeat domain 1	4	-9685060	AF274954	9948	4p16.1	Hs.128548 Hs.713658	15	actin binding protein binding cytoplasm cytoskeleton sensory perception of sound
203060_s_at	-0.741	6.456	-2.250	3.964e-02	0.361	-3.910	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	10	89409455	AF074331	9060	10q23-q24	Hs.524491	14	sulfate assimilation nucleotide binding skeletal system development adenylylsulfate kinase activity sulfate adenylyltransferase (ATP) activity protein binding ATP binding blood coagulation nucleotidyltransferase activity	Purine metabolism Selenoamino acid metabolism Sulfur metabolism Metabolic pathways
218704_at	0.262	4.638	2.250	3.968e-02	0.361	-3.911	RNF43	ring finger protein 43	17	-53786036	NM_017763	54894	17q22	Hs.584916	7	protein binding nucleus nuclear envelope endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
206896_s_at	0.480	5.585	2.250	3.968e-02	0.361	-3.911	GNG7	guanine nucleotide binding protein (G protein), gamma 7	19	-2462217	NM_005145	2788	19p13.3	Hs.515544	12	behavioral fear response signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction receptor guanylyl cyclase signaling pathway locomotory behavior regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
221629_x_at	0.286	6.634	2.250	3.969e-02	0.361	-3.912	C8orf30A	chromosome 8 open reading frame 30A	8	145264659, 145408687	AF151022	51236	8q24.3	Hs.300224	5	binding cellular_component biological_process
225774_at	-0.569	4.668	-2.249	3.970e-02	0.361	-3.912	RSPRY1	ring finger and SPRY domain containing 1	16	55777741	AA062971	89970	16q13	Hs.460885	5	protein binding extracellular region zinc ion binding metal ion binding
243017_at	0.301	4.732	2.249	3.971e-02	0.361	-3.912	LOC158572	hypothetical LOC158572	X	-49528067	AA032156	158572	Xp11.23	Hs.408191	3
223274_at	0.208	4.763	2.249	3.971e-02	0.361	-3.912	TCF19	transcription factor 19	6	31234281, 2577566, 2376100	BC002493	6941	6p21.3	Hs.584807	9	transcription factor activity protein binding nucleus regulation of transcription from RNA polymerase II promoter zinc ion binding cell proliferation regulation of transcription metal ion binding
225545_at	-0.817	9.032	-2.249	3.973e-02	0.361	-3.912	EEF2K	eukaryotic elongation factor-2 kinase	16	22125092	BF001312	29904	16p12.2	Hs.498892	22	nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP binding cytoplasm cytosol translational elongation protein amino acid phosphorylation translation factor activity, nucleic acid binding transferase activity
1552615_at	0.215	7.613	2.249	3.975e-02	0.362	-3.913	ACACB	acetyl-Coenzyme A carboxylase beta	12	108061584	NM_001093	32	12q24.11	Hs.234898	22	nucleotide binding acetyl-CoA carboxylase activity biotin carboxylase activity ATP binding cytoplasm Golgi apparatus cytosol fatty acid biosynthetic process metabolic process biotin binding membrane ligase activity manganese ion binding regulation of fatty acid oxidation metal ion binding	Fatty acid biosynthesis Pyruvate metabolism Propanoate metabolism Metabolic pathways Insulin signaling pathway Adipocytokine signaling pathway
225747_at	0.438	10.723	2.249	3.977e-02	0.362	-3.913	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)	12	54946908, 54947333	AL521634	93058	12q13.3	Hs.4096	5	mitochondrion
223279_s_at	-0.369	9.371	-2.249	3.977e-02	0.362	-3.913	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	15	-68733946, -68733946	AF322916	55075	15q22-q24	Hs.108049	12	molecular_function protein binding extracellular region membrane fraction soluble fraction nucleus nuclear envelope cytoplasm cytosol cytoskeleton DNA damage response, signal transduction resulting in induction of apoptosis induction of apoptosis by oxidative stress response to UV viral reproduction positive regulation of protein import into nucleus negative regulation of NF-kappaB import into nucleus positive regulation of apoptosis positive regulation of caspase activity apoptosome perinuclear region of cytoplasm negative regulation of inflammatory response
239057_at	-0.488	11.264	-2.249	3.978e-02	0.362	-3.914	LMOD2	leiomodin 2 (cardiac)	7	123083096	BF438844	442721	7q31.32	Hs.592260	6	actin binding tropomyosin binding cytoskeleton
208216_at	0.249	4.663	2.248	3.981e-02	0.362	-3.914	DLX4	distal-less homeobox 4	17	45401560, 45405128	NM_001934	1748	17q21.33	Hs.591167	27	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding
237257_at	0.343	7.260	2.248	3.981e-02	0.362	-3.914	RAB4B	RAB4B, member RAS oncogene family	19	45976010	AI668580	53916	19q13.2	Hs.631539	5	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
205356_at	-0.370	10.338	-2.248	3.981e-02	0.362	-3.914	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	3	180853626	NM_003940	8975	3q26.2-q26.3	Hs.175322	11	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding
205147_x_at	0.323	4.177	2.248	3.984e-02	0.362	-3.915	NCF4	neutrophil cytosolic factor 4, 40kDa	22	35586975	NM_000631	4689	22q13.1	Hs.474781	51	cytoplasm cytosol immune response cell communication membrane phosphoinositide binding NADPH oxidase complex protein dimerization activity oxidation reduction	Leukocyte transendothelial migration
210329_s_at	-0.238	6.445	-2.247	3.991e-02	0.362	-3.917	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	5	155686344, 155686344	U58331	6444	5q33-q34	Hs.387207 Hs.644733	29	protein binding cytoplasm cytoskeleton plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex integral to membrane	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
218677_at	0.256	5.467	2.246	3.994e-02	0.362	-3.917	S100A14	S100 calcium binding protein A14	1	-151853355	NM_020672	57402	1q21.3	Hs.288998	7	calcium ion binding cytoplasm
204840_s_at	-0.819	2.701	-2.246	3.994e-02	0.362	-3.917	EEA1	early endosome antigen 1	12	-91690415	AI916242	8411	12q22	Hs.567367	32	calmodulin binding phosphatidylinositol binding intracellular membrane fraction cytoplasm early endosome cytosol serine-pyruvate aminotransferase complex vesicle fusion zinc ion binding membrane synaptic vesicle to endosome fusion extrinsic to plasma membrane GTP-dependent protein binding protein homodimerization activity early endosome to late endosome transport metal ion binding	Endocytosis
224867_at	0.267	10.403	2.246	3.994e-02	0.362	-3.917	C1orf151	chromosome 1 open reading frame 151	1	19796053	BF244614	440574	1p36.13	Hs.466662	4	membrane integral to membrane
214459_x_at	0.483	9.815	2.246	3.994e-02	0.362	-3.917	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	M12679	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
34406_at	0.310	7.568	2.246	3.996e-02	0.363	-3.918	PACS2	phosphofurin acidic cluster sorting protein 2	14	104852125	AB011174	23241	14q32.33	Hs.525626	10	mitochondrion endoplasmic reticulum endoplasmic reticulum lumen apoptosis
218894_s_at	0.259	4.628	2.246	3.996e-02	0.363	-3.918	MAGOHB	mago-nashi homolog B (Drosophila)	12	-10648060	NM_018048	55110	12p13.2	Hs.104650	6	RNA binding nucleus mRNA processing transport RNA splicing mRNA transport
208331_at	0.254	2.663	2.246	3.999e-02	0.363	-3.918	BPY2	basic charge, Y-linked, 2	Y	-25586437, 23539797, 25173538	NM_004678	9083	Yq11	Hs.664724	7
40093_at	0.238	6.833	2.246	4.000e-02	0.363	-3.918	BCAM	basal cell adhesion molecule (Lutheran blood group)	19	50004177, 50004177	X83425	4059	19q13.2	Hs.625725	31	laminin receptor activity plasma membrane integral to plasma membrane cell adhesion cell-matrix adhesion signal transduction external side of plasma membrane laminin binding
218730_s_at	0.686	3.207	2.245	4.005e-02	0.363	-3.919	OGN	osteoglycin	9	-94186069	NM_014057	4969	9q22	Hs.109439	24	molecular_function protein binding extracellular region proteinaceous extracellular matrix endoplasmic reticulum growth factor activity biological_process
215493_x_at	-0.325	6.499	-2.245	4.006e-02	0.363	-3.920	BTN2A1	butyrophilin, subfamily 2, member A1	6	26566167	AL121936	11120	6p22.1	Hs.159028	7	molecular_function integral to plasma membrane lipid metabolic process membrane
212402_at	-0.431	7.285	-2.244	4.009e-02	0.363	-3.920	ZC3H13	zinc finger CCCH-type containing 13	13	-45434314	BE895685	23091	13q14.13	Hs.136102	11	nucleic acid binding zinc ion binding metal ion binding
1553887_at	0.189	2.638	2.244	4.009e-02	0.363	-3.920	C19orf75	chromosome 19 open reading frame 75	19	56452775	NM_173635	284369	19q13.41	Hs.381087	2	membrane integral to membrane
214107_x_at	-0.275	7.039	-2.244	4.010e-02	0.363	-3.921	LOC440434	hypothetical protein FLJ11822	17		AW340850	440434	17q12	Hs.443837 Hs.655470 Hs.710586	2	aminopeptidase activity proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
227489_at	-0.293	7.224	-2.244	4.010e-02	0.363	-3.921	SMURF2	SMAD specific E3 ubiquitin protein ligase 2	17	-59971196	BE962027	64750	17q22-q23	Hs.705442	35	ubiquitin ligase complex ubiquitin-protein ligase activity intracellular nucleus cytoplasm plasma membrane protein modification process negative regulation of transcription ligase activity acid-amino acid ligase activity regulation of transforming growth factor beta receptor signaling pathway BMP signaling pathway ubiquitin-dependent SMAD protein catabolic process identical protein binding membrane raft	Ubiquitin mediated proteolysis Endocytosis TGF-beta signaling pathway
206296_x_at	0.223	5.331	2.244	4.011e-02	0.363	-3.921	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	19	-43770120	NM_007181	11184	19q13.1-q13.4	Hs.95424	29	nucleotide binding activation of MAPKKK activity protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding response to stress protein kinase cascade activation of JUN kinase activity MAP kinase kinase kinase kinase activity transferase activity peptidyl-serine phosphorylation	MAPK signaling pathway
243653_at	0.267	5.364	2.244	4.011e-02	0.363	-3.921	SHROOM3	shroom family member 3	4	77575276	AA236863	57619	4q21.1	Hs.702168 Hs.716254	10	cell morphogenesis neural tube closure columnar/cuboidal epithelial cell development actin binding protein binding cytoplasm cytoskeleton microtubule adherens junction pattern specification process regulation of cell shape apical plasma membrane actin cytoskeleton organization cell junction apical junction complex cellular pigment accumulation apical protein localization
1558077_s_at	0.231	4.430	2.244	4.011e-02	0.363	-3.921	MDH1B	malate dehydrogenase 1B, NAD (soluble)	2	-207310733	BG202523	130752	2q33.3	Hs.147816	1	binding carbohydrate metabolic process tricarboxylic acid cycle malate metabolic process oxidoreductase activity malate dehydrogenase activity oxidation reduction
216127_at	0.236	5.166	2.244	4.012e-02	0.363	-3.921	PDIA2	protein disulfide isomerase family A, member 2	16	273118	Z84717	64714	16p13.3	Hs.66581	30	response to hypoxia protein disulfide isomerase activity protein binding endoplasmic reticulum endoplasmic reticulum lumen protein folding protein retention in ER lumen isomerase activity cell redox homeostasis
206146_s_at	0.218	5.147	2.244	4.012e-02	0.363	-3.921	RHAG	Rh-associated glycoprotein	6	-49680848	AF178841	6005	6p21.1-p11	Hs.120950	35	plasma membrane plasma membrane integral to plasma membrane transport cellular ion homeostasis ammonium transmembrane transporter activity ammonium transmembrane transporter activity carbon dioxide transport ammonium transport ammonium transport ankyrin binding ammonia transporter activity
223816_at	0.226	3.158	2.244	4.012e-02	0.363	-3.921	SLC46A2	solute carrier family 46, member 2	9	-114681021	AF242557	57864	9q32	Hs.512668	8	plasma membrane transport cell surface symporter activity tetracycline:hydrogen antiporter activity tetracycline transport integral to membrane response to antibiotic
204384_at	-0.258	6.273	-2.244	4.012e-02	0.363	-3.921	GOLGA2	golgi autoantigen, golgin subfamily a, 2	9	-130057928	NM_004486	2801	9q34.11	Hs.155827	45	protein binding Golgi apparatus membrane
218464_s_at	-0.242	7.473	-2.244	4.013e-02	0.363	-3.921	C17orf63	chromosome 17 open reading frame 63	17	-24107122	NM_018182	55731	17q11.2	Hs.564533	4
221378_at	0.372	4.609	2.244	4.015e-02	0.363	-3.922	CER1	cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)	9	-14709731	NM_005454	9350	9p23-p22	Hs.248204	12	molecular_function cytokine activity protein binding extracellular region extracellular region extracellular space biological_process negative regulation of cell proliferation anterior/posterior axis specification negative regulation of BMP signaling pathway cell migration involved in gastrulation	Wnt signaling pathway
232013_at	-0.278	3.153	-2.243	4.019e-02	0.363	-3.923	C9orf102	chromosome 9 open reading frame 102	9	97677720	AL133663	375748	9q22.32	Hs.432364	4	nucleotide binding DNA binding helicase activity ATP binding nucleus DNA repair response to DNA damage stimulus ATP-dependent helicase activity hydrolase activity
209265_s_at	-0.241	7.611	-2.243	4.019e-02	0.363	-3.923	METTL3	methyltransferase like 3	14	-21036121	BC001650	56339	14q11.1	Hs.168799	8	RNA methylation RNA binding nucleus nucleoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process methyltransferase activity mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity nuclear speck transferase activity
242040_at	0.290	5.250	2.243	4.020e-02	0.363	-3.923	GCNT7	glucosaminyl (N-acetyl) transferase family member 7	20	-54499954	AW025411	140687	20q13.2	Hs.655916		Golgi apparatus acetylglucosaminyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups
203041_s_at	-0.461	6.775	-2.243	4.020e-02	0.363	-3.923	LAMP2	lysosomal-associated membrane protein 2	X	-119454376, -119444030	J04183	3920	Xq24	Hs.496684	52	membrane fraction lysosomal membrane late endosome plasma membrane plasma membrane integral to membrane platelet dense granule membrane platelet dense granule membrane	Lysosome
1556907_at	0.248	2.573	2.243	4.023e-02	0.363	-3.923	ZNF474	zinc finger protein 474	5	121493113	BM979960	133923	5q23.2	Hs.646680	3	intracellular zinc ion binding metal ion binding
224568_x_at	-0.861	7.811	-2.243	4.023e-02	0.363	-3.923	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AW005982	378938	11q13.1	Hs.642877 Hs.714394	8
204008_at	0.327	5.639	2.242	4.025e-02	0.363	-3.924	DNAL4	dynein, axonemal, light chain 4	22	-37504458	NM_005740	10126	22q13.1	Hs.632766	11	microtubule motor activity microtubule motor activity centrosome axonemal dynein complex microtubule plasma membrane microtubule-based movement ATPase activity, coupled	Huntington's disease
1563315_s_at	-0.195	5.312	-2.242	4.026e-02	0.363	-3.924	ERICH1	glutamate-rich 1	8	-604199	BC016017	157697	8p23.3	Hs.655310	4
1553555_at	0.313	4.425	2.242	4.026e-02	0.363	-3.924	TAS2R38	taste receptor, type 2, member 38	7	-141318899	NM_176817	5726	7q34	Hs.647085	29	receptor activity G-protein coupled receptor activity signal transduction G-protein coupled receptor protein signaling pathway membrane integral to membrane response to stimulus sensory perception of taste	Taste transduction
201064_s_at	-0.356	9.863	-2.242	4.027e-02	0.363	-3.924	PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	1	-39799071	NM_003819	8761	1p32-p36	Hs.169900	17	nucleotide binding RNA binding protein binding cytoplasm RNA processing RNA catabolic process translation blood coagulation poly(A) RNA binding poly(U) RNA binding poly(C) RNA binding
208889_s_at	0.257	5.337	2.242	4.028e-02	0.363	-3.925	NCOR2	nuclear receptor co-repressor 2	12	-123374913	AI373205	9612	12q24	Hs.137510	109	DNA binding transcription corepressor activity Notch binding protein binding nucleus nucleolus negative regulation of specific transcription from RNA polymerase II promoter regulation of transcription	Notch signaling pathway
217821_s_at	-0.343	5.997	-2.242	4.029e-02	0.363	-3.925	WBP11	WW domain binding protein 11	12	-14830678	AF118023	51729	12p12.3	Hs.655138	13	single-stranded DNA binding protein binding nucleus cytoplasm rRNA processing mRNA processing RNA splicing protein phosphatase type 1 regulator activity nuclear speck
217885_at	-0.261	7.351	-2.241	4.032e-02	0.363	-3.925	IPO9	importin 9	1	200064910	NM_018085	55705	1q32.1	Hs.596014	12	protein import into nucleus, docking nucleus nuclear pore cytoplasm intracellular protein transport Ran GTPase binding protein transporter activity histone binding
213569_at	0.273	5.432	2.241	4.034e-02	0.363	-3.926	ANGEL1	angel homolog 1 (Drosophila)	14	-76323338	AV705485	23357	14q24.3	Hs.497448	5
238140_at	0.371	3.468	2.241	4.034e-02	0.363	-3.926	ARV1	ARV1 homolog (S. cerevisiae)	1	229181445	AI346356	64801	1q42.2	Hs.275736	6	lipid metabolic process sphingolipid metabolic process membrane integral to membrane
215501_s_at	-0.624	6.548	-2.241	4.035e-02	0.363	-3.926	DUSP10	dual specificity phosphatase 10	1	-219941388, -219941388	AK022513	11221	1q41	Hs.497822	15	protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation response to stress JNK cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
207117_at	0.481	2.631	2.241	4.036e-02	0.363	-3.926	ZNF117	zinc finger protein 117	7	-64072264	NM_015852	51351	7q11.21	Hs.250693	5	molecular_function transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding metal ion binding
1564367_at	0.307	3.900	2.241	4.036e-02	0.363	-3.926	CXorf25	chromosome X open reading frame 25	X		AK094108	392459	Xp11.23	Hs.562045	1
211381_x_at	0.333	3.590	2.241	4.038e-02	0.363	-3.927	SPAG11B	sperm associated antigen 11B	8	-7306317, -7295495, -7295495, -7292685, 7742811	AF168617	10407	8p23-p22	Hs.2717	10	molecular_function extracellular region spermatogenesis
244264_at	0.282	3.472	2.240	4.040e-02	0.364	-3.927	KLRG2	killer cell lectin-like receptor subfamily G, member 2	7	-138788627	AW197495	346689	7q34	Hs.17572	2	binding sugar binding membrane integral to membrane
221087_s_at	0.388	6.180	2.240	4.040e-02	0.364	-3.927	APOL3	apolipoprotein L, 3	22	-34866317, -34866317	NM_014349	80833	22q13.1	Hs.474737	11	signal transducer activity lipid transporter activity extracellular region cytoplasm lipid transport inflammatory response lipid binding lipoprotein metabolic process positive regulation of I-kappaB kinase/NF-kappaB cascade
209909_s_at	-0.830	2.853	-2.240	4.041e-02	0.364	-3.927	TGFB2	transforming growth factor, beta 2	1	216586013	M19154	7042	1q41	Hs.133379	112	cell morphogenesis skeletal system development cartilage condensation angiogenesis beta-amyloid binding blood vessel development eye development response to hypoxia blood vessel remodeling receptor signaling protein serine/threonine kinase activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding cytokine activity extracellular region extracellular region extracellular region extracellular space induction of apoptosis activation-induced cell death of T cells cell cycle arrest transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation cell-cell signaling axon guidance salivary gland morphogenesis growth factor activity cell death positive regulation of cell proliferation glial cell migration embryonic development positive regulation of epithelial cell migration negative regulation of alkaline phosphatase activity positive regulation of epithelial to mesenchymal transition positive regulation of phosphoinositide 3-kinase cascade menstrual cycle phase hemopoiesis collagen fibril organization positive regulation of cell growth negative regulation of cell growth axon neutrophil chemotaxis neutrophil chemotaxis extracellular matrix hair follicle morphogenesis platelet alpha granule lumen activation of protein kinase activity response to progesterone stimulus positive regulation of stress-activated MAPK cascade regulation of transforming growth factor-beta2 production positive regulation of cell adhesion mediated by integrin wound healing dopamine biosynthetic process odontogenesis protein homodimerization activity cell soma positive regulation of neuron apoptosis cell-cell junction organization positive regulation of integrin biosynthetic process positive regulation of ossification positive regulation of cell cycle positive regulation of heart contraction protein heterodimerization activity somatic stem cell division neuron fate commitment neuron development generation of neurons negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive regulation of protein secretion negative regulation of immune response positive regulation of immune response positive regulation of catagen positive regulation of cardioblast differentiation cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition pathway-restricted SMAD protein phosphorylation	MAPK signaling pathway Cytokine-cytokine receptor interaction Cell cycle TGF-beta signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hypertrophic cardiomyopathy (HCM)
201485_s_at	-0.506	8.019	-2.240	4.041e-02	0.364	-3.927	RCN2	reticulocalbin 2, EF-hand calcium binding domain	15	75011016	BC004892	5955	15q23	Hs.79088	10	calcium ion binding protein binding endoplasmic reticulum endoplasmic reticulum lumen
206192_at	0.345	4.815	2.240	4.042e-02	0.364	-3.928	CDSN	corneodesmosin	6	-31190848, -2534080, -2332634	L20815	1041	6p21.3	Hs.556031	25	cornified envelope molecular_function extracellular region epidermis development cell-cell adhesion desmosome keratinocyte differentiation protein homodimerization activity
202099_s_at	0.244	5.927	2.240	4.044e-02	0.364	-3.928	DGCR2	DiGeorge syndrome critical region gene 2	22	-17403794	H42875	9993	22q11.21	Hs.517357	14	receptor activity protein binding sugar binding microsome cell adhesion organ morphogenesis membrane integral to membrane response to drug
208687_x_at	-0.529	11.482	-2.240	4.045e-02	0.364	-3.928	HSPA8	heat shock 70kDa protein 8	11	-122433409	AF352832	3312	11q24.1	Hs.702021	145	nucleotide binding protein binding ATP binding intracellular cytoplasm protein folding response to unfolded protein cell surface melanosome ATPase activity, coupled interspecies interaction between organisms	MAPK signaling pathway Endocytosis Antigen processing and presentation
213471_at	-0.268	4.688	-2.240	4.045e-02	0.364	-3.928	NPHP4	nephronophthisis 4	1	-5845456	AB014573	261734	1p36.22	Hs.462348	13	structural molecule activity protein binding centrosome cilium microtubule basal body signal transduction visual behavior membrane cell-cell adhesion actin cytoskeleton organization
1554173_at	0.249	5.860	2.239	4.047e-02	0.364	-3.929	CD300LB	CD300 molecule-like family member b	17	-70028907	BC028091	124599	17q25.1	Hs.313343	5	receptor activity plasma membrane immune response integral to membrane
207926_at	0.348	4.247	2.239	4.050e-02	0.364	-3.929	GP5	glycoprotein V (platelet)	3	-195596838	NM_004488	2814	3q29	Hs.73734	22	protein binding plasma membrane plasma membrane integral to plasma membrane cell adhesion blood coagulation platelet alpha granule membrane	ECM-receptor interaction Hematopoietic cell lineage
229230_at	0.217	3.513	2.239	4.050e-02	0.364	-3.929	OSTalpha	organic solute transporter alpha	3	197427779	AA702685	200931	3q29	Hs.630585	11	transporter activity plasma membrane transport integral to membrane
227775_at	0.227	3.725	2.239	4.051e-02	0.364	-3.929	BRUNOL6	bruno-like 6, RNA binding protein (Drosophila)	15	-70364121	BE467313	60677	15q24	Hs.348342	5	nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome RNA binding nucleus cytoplasm mRNA processing
222508_s_at	-0.283	6.176	-2.239	4.051e-02	0.364	-3.930	ARGLU1	arginine and glutamate rich 1	13	-105993662	AU135021	55082	13q33.3	Hs.508644 Hs.701016	3
1555416_a_at	0.199	5.260	2.239	4.052e-02	0.364	-3.930	ALOX15B	arachidonate 15-lipoxygenase, type B	17	7883082	AF468053	247	17p13.1	Hs.111256	18	iron ion binding intracellular intracellular cytoplasm lipid metabolic process fatty acid metabolic process induction of apoptosis negative regulation of cell proliferation negative regulation of cell proliferation lipoxygenase activity oxidoreductase activity leukotriene biosynthetic process negative regulation of cell migration prostate gland development regulation of epithelial cell differentiation negative regulation of cell cycle negative regulation of cell cycle negative regulation of growth negative regulation of growth metal ion binding arachidonate 15-lipoxygenase activity arachidonate 15-lipoxygenase activity oxidation reduction	Arachidonic acid metabolism Metabolic pathways
223899_at	0.297	4.712	2.239	4.053e-02	0.364	-3.930	PBRM1	polybromo 1	3	-52554407, -52554407	AF225870	55193	3p21	Hs.189920	19	nuclear chromosome DNA binding chromatin binding protein binding nucleus chromatin remodeling mitosis regulation of transcription
217358_at	0.252	5.171	2.239	4.054e-02	0.364	-3.930	DNAJC16	DnaJ (Hsp40) homolog, subfamily C, member 16	1	15725938	AL137715	23341	1p36.1	Hs.655410	6	protein folding membrane integral to membrane heat shock protein binding cell redox homeostasis unfolded protein binding
203658_at	0.686	8.529	2.239	4.055e-02	0.364	-3.930	SLC25A20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	3	-48869359	BC001689	788	3p21.31	Hs.13845	19	transporter activity binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane transport carnitine shuttle acyl carnitine transporter activity membrane integral to membrane regulation of fatty acid oxidation
208653_s_at	-0.493	4.221	-2.238	4.057e-02	0.364	-3.931	CD164	CD164 molecule, sialomucin	6	-109794411	AF263279	8763	6q21	Hs.520313 Hs.644693	17	extracellular region plasma membrane integral to plasma membrane immune response cell adhesion heterophilic cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation	Lysosome
201970_s_at	-0.266	6.740	-2.238	4.062e-02	0.364	-3.932	NASP	nuclear autoantigenic sperm protein (histone-binding)	1	45822303	NM_002482	4678	1p34.1	Hs.319334	28	blastocyst development protein binding nucleus cytoplasm DNA replication cell cycle cell proliferation protein transport histone exchange Hsp90 protein binding
209203_s_at	-0.512	6.425	-2.238	4.062e-02	0.364	-3.932	BICD2	bicaudal D homolog 2 (Drosophila)	9	-94513465	BC002327	23299	9q22.31	Hs.436939	15	protein binding cytoplasm Golgi apparatus cytoskeleton transport microtubule-based movement
221230_s_at	-0.404	7.329	-2.237	4.065e-02	0.364	-3.932	ARID4B	AT rich interactive domain 4B (RBP1-like)	1	-233396832	NM_016374	51742	1q42.1-q43	Hs.533633 Hs.575782	12	chromatin molecular_function DNA binding chromatin binding cellular_component intracellular nucleus cytoplasm chromatin assembly or disassembly biological_process regulation of transcription
239027_at	0.255	5.431	2.237	4.065e-02	0.364	-3.933	DOCK8	dedicator of cytokinesis 8	9	204864	AV760561	81704	9p24.3	Hs.132599	11	guanyl-nucleotide exchange factor activity GTP binding GTPase binding
232572_at	0.298	2.945	2.237	4.067e-02	0.364	-3.933	PCA3	prostate cancer antigen 3 (non-protein coding)	9	78569173	AF103907	50652	9q21-q22	Hs.663766	11
240275_at	0.258	3.827	2.237	4.069e-02	0.364	-3.933	ARMC3	armadillo repeat containing 3	10	23256959	AI936559	219681	10p12.31	Hs.659807	4	binding
208089_s_at	-0.472	5.503	-2.237	4.070e-02	0.364	-3.934	TDRD3	tudor domain containing 3	13	59868591, 59869427	NM_030794	81550	13q21.2	Hs.525061	12	nucleic acid binding nucleus cytoplasm
206462_s_at	-0.283	2.874	-2.237	4.070e-02	0.364	-3.934	NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15	-86321598, -86220991	NM_002530	4916	15q25	Hs.410969 Hs.706364	72	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway multicellular organismal development nervous system development membrane transferase activity cell differentiation neurotrophin binding	Neurotrophin signaling pathway
210427_x_at	-0.603	9.499	-2.236	4.073e-02	0.365	-3.934	ANXA2	annexin A2	15	-58426642, -58426641	BC001388	302	15q21-q22	Hs.511605	137	skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm
210119_at	0.389	3.506	2.236	4.074e-02	0.365	-3.934	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	21	38550533, 38550739, 38566298	U73191	3772	21q22.2	Hs.411299	18	inward rectifier potassium channel activity voltage-gated ion channel activity potassium channel activity protein binding cytoplasm plasma membrane integral to plasma membrane focal adhesion ion transport potassium ion transport potassium ion binding
215734_at	0.319	4.771	2.236	4.075e-02	0.365	-3.935	C19orf36	chromosome 19 open reading frame 36	19	2047867	AW182303	113177	19p13.3	Hs.424049	3	extracellular region
235792_x_at	0.299	5.251	2.236	4.078e-02	0.365	-3.935	PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide	11	-17064699	AU154663	5286	11p15.5-p14	Hs.175343	39	nucleotide binding inositol or phosphatidylinositol kinase activity protein binding ATP binding nucleus cytoplasm Golgi apparatus plasma membrane phosphoinositide 3-kinase complex phosphatidylinositol biosynthetic process cell communication 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor clathrin-coated vesicle cytoplasmic vesicle phosphatidylinositol-4-phosphate 3-kinase activity phosphoinositide binding phosphoinositide phosphorylation phosphoinositide-mediated signaling	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
225258_at	0.368	6.066	2.235	4.079e-02	0.365	-3.936	FBLIM1	filamin binding LIM protein 1	1	15957841, 15963580, 15964045	AL133035	54751	1p36.21	Hs.530101	16	protein binding cytoplasm cytoskeleton focal adhesion cell cortex cell adhesion zinc ion binding regulation of cell shape cell junction metal ion binding
232620_at	0.324	6.406	2.235	4.079e-02	0.365	-3.936	WDR93	WD repeat domain 93	15	88035031	AL390084	56964	15q26.1	Hs.177557	2
211938_at	-0.254	10.524	-2.235	4.081e-02	0.365	-3.936	EIF4B	eukaryotic translation initiation factor 4B	12	51686328	BF247371	1975	12q13.13	Hs.648394 Hs.702041	23	nucleotide binding RNA binding translation initiation factor activity cytosol translation regulation of translational initiation eukaryotic translation initiation factor 4F complex	mTOR signaling pathway
214482_at	-0.315	5.218	-2.235	4.082e-02	0.365	-3.936	ZBTB25	zinc finger and BTB domain containing 25	14	-64023307	NM_006977	7597	14q23-q24	Hs.654571	6	transcription factor activity protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
212154_at	-0.661	5.055	-2.235	4.083e-02	0.365	-3.936	SDC2	syndecan 2	8	97575057	AI380298	6383	8q22-q23	Hs.1501 Hs.598247	72	molecular_function integral to plasma membrane cytoskeletal protein binding biological_process membrane	ECM-receptor interaction Cell adhesion molecules (CAMs)
236640_at	0.422	4.774	2.235	4.084e-02	0.365	-3.936	LOC399959	hypothetical LOC399959	11	-121465022	AI638169	399959	11q24.1	Hs.44098	2
1598_g_at	0.395	8.594	2.235	4.084e-02	0.365	-3.937	GAS6	growth arrest-specific 6	13	113546896, 113574925, 113577228	L13720	2621	13q34	Hs.646346	45	receptor binding calcium ion binding extracellular region signal transduction cell proliferation organ regeneration regulation of growth
214543_x_at	-0.397	8.054	-2.235	4.086e-02	0.365	-3.937	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	AF142421	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
234698_at	0.243	4.887	2.234	4.088e-02	0.365	-3.937	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)	21	-29166383	AK021678	29104	21q21.3	Hs.163846	6	nucleic acid binding protein binding protein methyltransferase activity transferase activity positive regulation of cell growth methylation protein complex
1554476_x_at	0.414	3.806	2.234	4.089e-02	0.365	-3.938	ZNF808	zinc finger protein 808	19	57722720	BC033230	388558	19q13.41	Hs.235167	2	DNA binding intracellular nucleus transcription regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207064_s_at	0.272	4.253	2.234	4.090e-02	0.365	-3.938	AOC2	amine oxidase, copper containing 2 (retina-specific)	17	38250134	NM_009590	314	17q21	Hs.143102	5	copper ion binding calcium ion binding catecholamine metabolic process visual perception amine oxidase activity electron carrier activity amine metabolic process oxidoreductase activity quinone binding oxidation reduction	Glycine, serine and threonine metabolism Tyrosine metabolism Phenylalanine metabolism beta-Alanine metabolism Isoquinoline alkaloid biosynthesis Tropane, piperidine and pyridine alkaloid biosynthesis Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
228101_at	0.278	5.045	2.234	4.090e-02	0.365	-3.938	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	9	-71232268	AI693178	320	9q13-q21.1	Hs.171939 Hs.592974	35	in utero embryonic development protein binding protein complex assembly intracellular protein transport cell adhesion synaptic transmission nervous system development locomotory behavior synaptic vesicle axon cargo transport regulation of gene expression glutamate secretion gamma-aminobutyric acid secretion multicellular organism growth
215145_s_at	0.236	4.045	2.234	4.092e-02	0.365	-3.938	CNTNAP2	contactin associated protein-like 2	7	145444385	AC005378	26047	7q35-q36	Hs.655684	27	receptor binding cell adhesion signal transduction neuron recognition membrane integral to membrane transmission of nerve impulse	Cell adhesion molecules (CAMs)
212731_at	-0.467	8.864	-2.233	4.095e-02	0.365	-3.939	ANKRD46	ankyrin repeat domain 46	8	-101602175	U79297	157567	8q22.2	Hs.530199	5	membrane integral to membrane
205512_s_at	-0.370	8.186	-2.233	4.097e-02	0.365	-3.939	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	X	-129091019, -129091019, -129091018	NM_004208	9131	Xq25-q26	Hs.424932	58	DNA binding protein binding nucleus cytoplasm mitochondrion mitochondrial intermembrane space DNA fragmentation involved in apoptosis apoptosis DNA damage response, signal transduction resulting in induction of apoptosis electron carrier activity oxidoreductase activity cell redox homeostasis FAD binding oxidation reduction	Apoptosis
237350_at	0.280	5.861	2.233	4.097e-02	0.365	-3.939	TTC36	tetratricopeptide repeat domain 36	11	117903419	AW027968	143941	11q23.3	Hs.653449	2
230206_at	-0.293	5.000	-2.233	4.101e-02	0.366	-3.940	DOCK5	dedicator of cytokinesis 5	8	25098203	AI692645	80005	8p21.2	Hs.195403	7	guanyl-nucleotide exchange factor activity cytoplasm
211285_s_at	-0.331	9.439	-2.232	4.103e-02	0.366	-3.941	UBE3A	ubiquitin protein ligase E3A	15	-23133488, -23133488, -23133488	U84404	7337	15q11-q13	Hs.598862	76	ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms	Ubiquitin mediated proteolysis
223577_x_at	-0.441	7.366	-2.232	4.103e-02	0.366	-3.941	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AA827878	378938	11q13.1	Hs.642877 Hs.714394	8
1565795_at	0.334	4.078	2.232	4.105e-02	0.366	-3.941	DUOX1	dual oxidase 1	15	43209483	BI768821	53905	15q15.3	Hs.272813	28	peroxidase activity calcium ion binding plasma membrane response to oxidative stress electron carrier activity integral to membrane NAD(P)H oxidase activity apical plasma membrane oxidoreductase activity cytokine-mediated signaling pathway heme binding cuticle development hormone biosynthetic process superoxide anion generation hydrogen peroxide catabolic process FAD binding NADP or NADPH binding hydrogen peroxide biosynthetic process response to cAMP response to cAMP oxidation reduction
1569949_at	-0.664	8.496	-2.232	4.108e-02	0.366	-3.942	GRK5	G protein-coupled receptor kinase 5	10	120957186	BC018116	2869	10q24-qter	Hs.524625	38	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity protein kinase C binding protein binding ATP binding phospholipid binding soluble fraction cytoplasm plasma membrane protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger tachykinin receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway transferase activity	Chemokine signaling pathway Endocytosis
211237_s_at	0.197	6.251	2.231	4.110e-02	0.366	-3.942	FGFR4	fibroblast growth factor receptor 4	5	176446526, 176449156	AF202063	2264	5q35.1-qter	Hs.165950	90	nucleotide binding induction of an organ receptor activity fibroblast growth factor receptor activity ATP binding plasma membrane integral to plasma membrane protein amino acid phosphorylation fibroblast growth factor receptor signaling pathway transferase activity lung development	MAPK signaling pathway Endocytosis Regulation of actin cytoskeleton
211323_s_at	0.401	4.727	2.231	4.110e-02	0.366	-3.942	ITPR1	inositol 1,4,5-triphosphate receptor, type 1	3	4510033	L38019	3708	3p26-p25	Hs.567295 Hs.715765	87	response to hypoxia ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium channel activity calcium ion binding protein binding endoplasmic reticulum ion transport calcium ion transport signal transduction cell death calcium ion transmembrane transporter activity membrane integral to membrane platelet dense granule membrane platelet dense tubular network membrane	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease Huntington's disease
205950_s_at	0.362	6.433	2.231	4.111e-02	0.366	-3.942	CA1	carbonic anhydrase I	8	-86427709, -86427709	NM_001738	759	8q13-q22.1	Hs.23118	30	carbonate dehydratase activity cytoplasm one-carbon metabolic process zinc ion binding lyase activity metal ion binding	Nitrogen metabolism
1566277_at	0.287	3.446	2.231	4.115e-02	0.366	-3.943	OR5E1P	olfactory receptor, family 5, subfamily E, member 1 pseudogene	11	7827173	AF309699	26343	11p15.4	Hs.382973	2
207490_at	-0.318	6.786	-2.231	4.116e-02	0.366	-3.943	TUBA4B	tubulin, alpha 4b (pseudogene)	2	219826208	NM_025019	80086	2q35	Hs.664469	7	nucleotide binding GTPase activity structural molecule activity GTP binding microtubule microtubule-based movement protein complex protein polymerization
233656_s_at	-0.356	5.605	-2.231	4.116e-02	0.366	-3.943	VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)	2	-63973170	AL359939	51542	2p13-p14	Hs.48499	8	protein binding protein transport retrograde transport, endosome to Golgi
208122_x_at	0.287	4.461	2.230	4.118e-02	0.366	-3.944	KIR2DS3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3	19	240823	NM_012313	3808	19q13.4	Hs.714920	44	receptor activity plasma membrane integral to plasma membrane cellular defense response	Antigen processing and presentation Natural killer cell mediated cytotoxicity
209586_s_at	-0.335	7.584	-2.230	4.119e-02	0.366	-3.944	PRUNE	prune homolog (Drosophila)	1	149247596	AF123539	58497	1q21	Hs.78524	8	inorganic diphosphatase activity protein binding nucleus cytoplasm focal adhesion hydrolase activity cell junction manganese ion binding metal ion binding	Purine metabolism
204196_x_at	0.252	3.483	2.230	4.121e-02	0.366	-3.944	PKNOX1	PBX/knotted 1 homeobox 1	21	43267711	NM_004571	5316	21q22.3	Hs.431043	25	angiogenesis specific RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex cytoplasm hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity
210164_at	0.376	4.117	2.230	4.121e-02	0.366	-3.945	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	14	-24170003	J03189	3002	14q11.2	Hs.1051	142	immunological synapse serine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis apoptosis cleavage of lamin peptidase activity cytolysis	Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
1553832_at	0.199	6.127	2.230	4.124e-02	0.366	-3.945	C21orf93	chromosome 21 open reading frame 93	21		NM_145179	246704	21q22.3	Hs.171428	1
226650_at	-0.431	6.071	-2.230	4.125e-02	0.366	-3.945	ZFAND2A	zinc finger, AN1-type domain 2A	7	-1159069	AI984061	90637	7p22.3	Hs.648111	2	nucleus cytoplasm zinc ion binding metal ion binding
233959_at	0.379	4.603	2.229	4.127e-02	0.366	-3.946	LOC221442	adenylate cyclase 10 pseudogene	6	41176750	W26606	221442	6p21.1	Hs.374076	1
209485_s_at	-0.281	9.487	-2.229	4.128e-02	0.366	-3.946	OSBPL1A	oxysterol binding protein-like 1A	18	-19996008, -19996008	W19983	114876	18q11.1	Hs.370725	12	phospholipid binding intracellular lipid transport steroid metabolic process cholesterol metabolic process vesicle-mediated transport
228126_x_at	0.223	4.605	2.229	4.128e-02	0.366	-3.946	CTXN1	cortexin 1	19	-7895380	BF982289	404217	19p13.2	Hs.657978	3	membrane integral to membrane
203162_s_at	0.358	6.274	2.229	4.129e-02	0.366	-3.946	KATNB1	katanin p80 (WD repeat containing) subunit B 1	16	56327160	NM_005886	10300	16q21	Hs.275675	14	spindle pole cytoplasm cytoskeleton microtubule protein targeting negative regulation of microtubule depolymerization cell cycle mitosis microtubule binding katanin complex microtubule-severing ATPase activity axon positive regulation of microtubule depolymerization dynein binding protein heterodimerization activity cell division
226586_at	0.248	6.132	2.229	4.129e-02	0.366	-3.946	ANKS6	ankyrin repeat and sterile alpha motif domain containing 6	9	-100534111	AW130559	203286	9q22.33	Hs.406890	7
203631_s_at	0.311	4.806	2.229	4.130e-02	0.366	-3.946	GPRC5B	G protein-coupled receptor, family C, group 5, member B	16	-19777793	AF202640	51704	16p12	Hs.148685	8	receptor activity G-protein coupled receptor activity nucleus plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane cytoplasmic vesicle
228627_at	-0.381	5.739	-2.229	4.131e-02	0.366	-3.947	TLK2	tousled-like kinase 2	17	57910117	AL041560	11011	17q23	Hs.445078	10	nucleotide binding regulation of chromatin assembly or disassembly protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus protein amino acid phosphorylation response to DNA damage stimulus cell cycle intracellular signaling cascade chromatin modification transferase activity
226703_at	0.203	6.685	2.229	4.131e-02	0.366	-3.947	NEURL4	neuralized homolog 4 (Drosophila)	17	-7159674	AL136870	84461	17p13	Hs.654794	3	protein binding
207511_s_at	-0.323	5.553	-2.229	4.133e-02	0.366	-3.947	C2orf24	chromosome 2 open reading frame 24	2	-219744862	NM_015680	27013	2q35	Hs.4973	5	membrane integral to membrane
201634_s_at	-0.626	6.283	-2.229	4.133e-02	0.366	-3.947	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	16	68015998	NM_030579	80777	16q22.1	Hs.461131	7	mitochondrion mitochondrial outer membrane mitochondrial inner membrane microsome transport enzyme activator activity membrane integral to membrane heme binding electron transport chain metal ion binding
221149_at	0.289	3.298	2.229	4.133e-02	0.366	-3.947	GPR77	G protein-coupled receptor 77	19	52532210	NM_018485	27202	19q13.33	Hs.534412	13	receptor activity G-protein coupled receptor activity C5a anaphylatoxin receptor activity cellular_component plasma membrane chemotaxis signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane
201335_s_at	-0.464	4.099	-2.228	4.134e-02	0.366	-3.947	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	11	119713155	NM_015313	23365	11q23.3	Hs.24598	26	G-protein-coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm G-protein coupled receptor protein signaling pathway intracellular signaling cascade membrane regulation of Rho protein signal transduction	Vascular smooth muscle contraction Axon guidance Regulation of actin cytoskeleton
206868_at	0.247	6.167	2.228	4.134e-02	0.366	-3.947	STARD8	StAR-related lipid transfer (START) domain containing 8	X	67784235, 67830217	NM_014725	9754	Xq13.1	Hs.95140	8	GTPase activator activity intracellular focal adhesion signal transduction cell junction
1552676_at	0.418	4.901	2.228	4.135e-02	0.366	-3.947	UCN3	urocortin 3 (stresscopin)	10	5396975	NM_053049	114131	10p15.1	Hs.511775	14	hormone activity protein binding extracellular region activation of adenylate cyclase activity by G-protein signaling pathway
209746_s_at	-0.259	7.095	-2.228	4.135e-02	0.366	-3.947	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	16	18986427	AF032900	10229	16p13.11-p12.3	Hs.157113	18	iron ion binding nucleus mitochondrion ubiquinone biosynthetic process oxidoreductase activity protein metabolic process	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
1553718_at	0.365	6.949	2.228	4.135e-02	0.366	-3.947	ZNF548	zinc finger protein 548	19	62593029	NM_152909	147694	19q13.43	Hs.657353	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
240409_at	0.315	3.169	2.228	4.135e-02	0.366	-3.947	SUGT1L1	SGT1, suppressor of G2 allele of SKP1 like 1 (S. cerevisiae)	13	-40269126	AI203405	283507	13q14.11	Hs.442781 Hs.709973	2
206015_s_at	-0.362	8.121	-2.228	4.136e-02	0.366	-3.948	FOXJ3	forkhead box J3	1	-42414796	NM_014947	22887	1pter-q31.3	Hs.26023	4	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
213292_s_at	-0.371	6.843	-2.228	4.137e-02	0.366	-3.948	SNX13	sorting nexin 13	7	-17796910	AA908770	23161	7p21.1	Hs.487648	10	signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding
219605_at	0.274	4.909	2.228	4.140e-02	0.367	-3.948	ZNF3	zinc finger protein 3	7	-99505529, -99499588	NM_017715	7551	7q22.1	Hs.435302	10	transcription factor activity intracellular nucleus nucleus nucleolus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding cell differentiation identical protein binding leukocyte activation metal ion binding
203077_s_at	-0.471	6.729	-2.227	4.144e-02	0.367	-3.949	SMAD2	SMAD family member 2	18	-43613464, -43613463, -43613463	NM_005901	4087	18q21.1	Hs.12253 Hs.705764	206	mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol	Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer
1569909_at	0.305	4.352	2.227	4.145e-02	0.367	-3.949	KRT79	keratin 79	12	-51501497	BC039148	338785	12q13.13	Hs.711471	3	structural molecule activity keratin filament
225283_at	-0.719	6.974	-2.227	4.145e-02	0.367	-3.949	ARRDC4	arrestin domain containing 4	15	96304936	AV701177	91947	15q26.3	Hs.6093	6
224938_at	-0.274	7.096	-2.227	4.147e-02	0.367	-3.950	NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	17	-24606979	AW007746	57532	17q11.2	Hs.462598	13	RNA binding protein binding nucleus cytoplasm Golgi apparatus polysomal ribosome
202769_at	-0.978	6.876	-2.227	4.148e-02	0.367	-3.950	CCNG2	cyclin G2	4	78297380	AW134535	901	4q21.1	Hs.13291	12	cell cycle checkpoint cytoplasm cell cycle mitosis cell division	p53 signaling pathway
223792_at	0.274	5.271	2.227	4.149e-02	0.367	-3.950	ZNF2	zinc finger protein 2	2	95194909	BC005068	7549	2q11.2	Hs.590916	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
217780_at	-0.273	9.161	-2.226	4.150e-02	0.367	-3.951	C19orf56	chromosome 19 open reading frame 56	19	-12639880	NM_016145	51398	19p13.2	Hs.108969 Hs.657204	4	membrane integral to membrane
224992_s_at	0.257	4.934	2.226	4.156e-02	0.368	-3.952	CMIP	c-Maf-inducing protein	16	80036275, 80086454	AI363061	80790	16q23	Hs.709248	7	nucleus cytoplasm
219504_s_at	-0.265	5.810	-2.225	4.158e-02	0.368	-3.952	RPAP2	RNA polymerase II associated protein 2	1	92537109	NM_024813	79871	1p22.1	Hs.444421	7	membrane integral to membrane
217788_s_at	-0.353	8.078	-2.225	4.163e-02	0.368	-3.953	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	1	228269578	NM_004481	2590	1q41-q42	Hs.716384	24	immunoglobulin biosynthetic process polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus Golgi stack membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding integral to Golgi membrane perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
1560765_a_at	0.280	5.035	2.225	4.163e-02	0.368	-3.953	ARHGAP22	Rho GTPase activating protein 22	10	-49324084	BC043540	58504	10q11.22	Hs.655672	5	angiogenesis GTPase activator activity intracellular nucleus cytoplasm signal transduction multicellular organismal development cell differentiation regulation of transcription
217765_at	-0.400	7.022	-2.225	4.164e-02	0.368	-3.954	NRBP1	nuclear receptor binding protein 1	2	27504976	NM_013392	29959	2p23	Hs.515876	18	protein kinase activity protein binding ATP binding cytoplasm cell cortex protein amino acid phosphorylation ER to Golgi vesicle-mediated transport endomembrane system membrane lamellipodium protein homodimerization activity perinuclear region of cytoplasm
233801_s_at	0.325	5.443	2.225	4.165e-02	0.368	-3.954	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	15	45797977, 45797977	AK022747	80031	15q21.1	Hs.511265	8	receptor activity cytoplasm plasma membrane multicellular organismal development nervous system development integral to membrane cell differentiation	Axon guidance
1559942_at	-0.422	4.414	-2.224	4.167e-02	0.368	-3.954	MDFIC	MyoD family inhibitor domain containing	7	114349444	BC040713	29969	7q31.1-q31.2	Hs.427236	7	nucleus nucleolus cytoplasm activation of JUN kinase activity regulation of Wnt receptor signaling pathway cyclin binding Tat protein binding interspecies interaction between organisms regulation of transcription positive regulation of viral transcription
233795_at	0.298	5.336	2.224	4.169e-02	0.368	-3.955	ODF3	outer dense fiber of sperm tails 3	11	186760	AL133658	113746	11p15.5	Hs.350949	2	outer dense fiber cytoplasm multicellular organismal development spermatogenesis cell differentiation
233261_at	0.385	3.599	2.224	4.171e-02	0.368	-3.955	EBF1	early B-cell factor 1	5	-158055500	AU145682	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
213764_s_at	-0.962	7.179	-2.224	4.172e-02	0.368	-3.955	MFAP5	microfibrillar associated protein 5	12	-8689806	AW665892	8076	12p13.1-p12.3	Hs.512842	9	microfibril extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix
222079_at	0.230	4.335	2.224	4.173e-02	0.368	-3.955	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	21	-38673821, -38673821	BF739971	2078	21q22.3	Hs.473819	66	transcription factor activity signal transducer activity protein binding nucleus regulation of transcription, DNA-dependent protein amino acid phosphorylation signal transduction multicellular organismal development cell proliferation sequence-specific DNA binding
233051_at	0.403	4.617	2.223	4.174e-02	0.368	-3.956	SLITRK2	SLIT and NTRK-like family, member 2	X	144707038, 144710703	AL109653	84631	Xq27.3	Hs.320368	10	protein binding axonogenesis membrane integral to membrane
224606_at	-0.396	7.421	-2.223	4.176e-02	0.368	-3.956	KLF6	Kruppel-like factor 6	10	-3808188	BG250721	1316	10p15	Hs.4055 Hs.709396	71	double-stranded DNA binding transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding transcription activator activity cytokine-mediated signaling pathway B cell differentiation wound healing positive regulation of transcription from RNA polymerase II promoter metal ion binding
221325_at	0.175	4.524	2.223	4.177e-02	0.368	-3.956	KCNK13	potassium channel, subfamily K, member 13	14	89597860	NM_022054	56659	14q31-q32	Hs.510191	8	voltage-gated ion channel activity potassium channel activity ion transport potassium ion transport membrane integral to membrane potassium ion binding
1553117_a_at	-0.334	3.728	-2.223	4.181e-02	0.369	-3.957	STK38	serine/threonine kinase 38	6	-36569646	NM_007271	11329	6p21	Hs.409578	21	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm protein modification process protein amino acid phosphorylation protein kinase cascade transferase activity MLL5-L complex
203022_at	0.379	5.552	2.222	4.182e-02	0.369	-3.957	RNASEH2A	ribonuclease H2, subunit A	19	12778427	NM_006397	10535	19p13.2	Hs.532851	8	RNA binding endonuclease activity ribonuclease H activity ribonuclease activity nucleus DNA replication RNA catabolic process hydrolase activity metal ion binding	DNA replication
227067_x_at	-0.430	5.871	-2.222	4.184e-02	0.369	-3.958	NOTCH2NL	Notch homolog 2 (Drosophila) N-terminal like	1	143920467	AW024960	388677	1q21.2	Hs.655156 Hs.683989 Hs.709526	5	calcium ion binding extracellular region cytoplasm Notch signaling pathway multicellular organismal development cell differentiation
32541_at	-0.339	7.208	-2.222	4.184e-02	0.369	-3.958	PPP3CC	protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform	8	22354540	S46622	5533	8p21.3	Hs.655661	21	phosphoprotein phosphatase activity iron ion binding calmodulin binding cytosol zinc ion binding activation of pro-apoptotic gene products hydrolase activity metal ion binding	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
205796_at	-0.319	3.406	-2.222	4.186e-02	0.369	-3.958	TCP11L1	t-complex 11 (mouse)-like 1	11	33017538, 33018136	NM_018393	55346	11p13	Hs.655341	4
226509_at	-0.554	6.918	-2.222	4.187e-02	0.369	-3.958	ZNF641	zinc finger protein 641	12	-47022178	AV700302	121274	12q13.11	Hs.23492	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
220637_at	0.281	3.950	2.221	4.190e-02	0.369	-3.959	FAM124B	family with sequence similarity 124B	2	-224951658	NM_024785	79843	2q36.2	Hs.147585	3	protein binding
223019_at	0.272	6.214	2.221	4.191e-02	0.369	-3.959	FAM129B	family with sequence similarity 129, member B	9	-129307438, -129307438	BC001979	64855	9q33.3-q34.11	Hs.522401	8
239824_s_at	0.457	4.861	2.221	4.192e-02	0.369	-3.959	TMEM107	transmembrane protein 107	17	-8017020	BF971873	84314	17p13.1	Hs.513933	4	molecular_function cellular_component biological_process membrane integral to membrane
1558426_x_at	0.281	7.256	2.221	4.193e-02	0.369	-3.959	ORAI2	ORAI calcium release-activated calcium modulator 2	7	101861000	BC016797	80228	7q22.1	Hs.363308	12	membrane integral to membrane
230394_at	0.253	4.407	2.221	4.196e-02	0.369	-3.960	TCP10L	t-complex 10 (mouse)-like	21	-32869022	AI336920	140290	21q22.11	Hs.42034	11
213261_at	0.368	5.451	2.221	4.197e-02	0.369	-3.960	LBA1	lupus brain antigen 1	3	-36843314	AA035414	9881	3p22.2	Hs.170999	3	binding
33494_at	0.582	8.704	2.221	4.197e-02	0.369	-3.960	ETFDH	electron-transferring-flavoprotein dehydrogenase	4	159812726	S69232	2110	4q32-q35	Hs.155729	16	electron-transferring-flavoprotein dehydrogenase activity iron ion binding mitochondrion mitochondrial inner membrane fatty acid beta-oxidation transport response to oxidative stress electron carrier activity membrane integral to membrane oxidoreductase activity electron transport chain integral to mitochondrial inner membrane oxidoreductase activity, oxidizing metal ions with flavin as acceptor metal ion binding ubiquinone binding FAD binding 4 iron, 4 sulfur cluster binding
1564352_at	0.253	3.844	2.221	4.197e-02	0.369	-3.960	CECR3	cat eye syndrome chromosome region, candidate 3	22		AF277398	27442		Hs.517394	1
207394_at	0.381	3.848	2.220	4.199e-02	0.369	-3.961	ZNF137	zinc finger protein 137	19	57791748	NM_003438	7696	19q13.4	Hs.373648	3
1552499_a_at	0.391	3.373	2.220	4.201e-02	0.369	-3.961	ZSCAN20	zinc finger and SCAN domain containing 20	1	33710818	NM_145238	7579	1p34.3	Hs.442705	6	transcription factor activity intracellular nucleus nucleolus mitochondrion regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225680_at	0.277	6.042	2.220	4.201e-02	0.369	-3.961	LRWD1	leucine-rich repeats and WD repeat domain containing 1	7	101892394	BE896303	222229	7q22.1	Hs.274135	2	protein binding
210124_x_at	0.332	5.829	2.220	4.202e-02	0.369	-3.962	SEMA4F	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F	2	74734900	AL136552	10505	2p13.1	Hs.25887	14	receptor activity membrane fraction endoplasmic reticulum plasma membrane integral to plasma membrane cell-cell signaling multicellular organismal development nervous system development axon guidance cell differentiation	Axon guidance
215718_s_at	-0.277	3.970	-2.220	4.204e-02	0.369	-3.962	PHF3	PHD finger protein 3	6	64414389	AI949220	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
207695_s_at	0.580	4.624	2.220	4.204e-02	0.369	-3.962	IGSF1	immunoglobulin superfamily, member 1	X	-130245822, -130235162	NM_001555	3547	Xq25	Hs.22111	15	receptor activity protein binding extracellular region signal transduction membrane integral to membrane regulation of transcription inhibin beta-A binding inhibin beta-B binding
209594_x_at	0.340	4.895	2.220	4.205e-02	0.369	-3.962	PSG9	pregnancy specific beta-1-glycoprotein 9	19	-48449274	M34421	5678	19q13.2	Hs.502092	17	extracellular region female pregnancy
225355_at	0.440	7.699	2.220	4.205e-02	0.369	-3.962	NEURL1B	neuralized homolog 1B (Drosophila)	5	172000880	AK026748	54492	5q35.1	Hs.91521	3	protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
216389_s_at	0.310	6.333	2.220	4.205e-02	0.369	-3.962	DCAF11	DDB1 and CUL4 associated factor 11	14	23653745, 23653825, 23654331, 23654333	AF283773	80344	14q11.2	Hs.525251	9	protein binding
224719_s_at	0.373	9.100	2.220	4.206e-02	0.369	-3.962	C12orf57	chromosome 12 open reading frame 57	12	6923463	BG339653	113246	12p13.31	Hs.405913 Hs.591045	5
224622_at	-0.309	7.355	-2.219	4.207e-02	0.369	-3.962	TBC1D14	TBC1 domain family, member 14	4	6962071, 6962395, 7039789	AB037743	57533	4p16.1	Hs.518611	7	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
227557_at	0.300	4.267	2.219	4.207e-02	0.369	-3.963	SCARF2	scavenger receptor class F, member 2	22	-19108874	AI127800	91179	22q11.21	Hs.474251	4	receptor activity scavenger receptor activity protein binding cell adhesion heterophilic cell adhesion membrane integral to membrane
213295_at	-0.610	7.041	-2.219	4.208e-02	0.369	-3.963	CYLD	cylindromatosis (turban tumor syndrome)	16	49333461, 49333529	AA555096	1540	16q12.1	Hs.578973	54	structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm	RIG-I-like receptor signaling pathway
203350_at	-0.255	6.437	-2.219	4.209e-02	0.369	-3.963	AP1G1	adaptor-related protein complex 1, gamma 1 subunit	16	-70320405	NM_001128	164	16q23	Hs.461253	36	transporter activity protein binding cytoplasm cytosol intracellular protein transport endocytosis protein transporter activity membrane clathrin adaptor complex clathrin-coated vesicle cytoplasmic vesicle Golgi apparatus part perinuclear region of cytoplasm	Lysosome
212853_at	-0.266	6.281	-2.219	4.209e-02	0.369	-3.963	DCUN1D4	DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)	4	52404032	AA779297	23142	4q12	Hs.605388	10	nucleus
228967_at	-0.711	8.160	-2.219	4.210e-02	0.369	-3.963	EIF1	eukaryotic translation initiation factor 1	17	37098652	BE964053	10209	17q21.2	Hs.150580	10	translation initiation factor activity cytoplasm regulation of translational initiation response to stress
219892_at	-0.688	7.987	-2.219	4.211e-02	0.369	-3.963	TM6SF1	transmembrane 6 superfamily member 1	15	81567327	NM_023003	53346	15q24-q26	Hs.513094	4	molecular_function biological_process membrane integral to membrane
233191_at	-0.252	2.669	-2.219	4.211e-02	0.369	-3.963	RUFY2	RUN and FYVE domain containing 2	10	-69806955, -69773280	AB040970	55680	10q21.3	Hs.653144	5	nucleus zinc ion binding metal ion binding
212558_at	-0.379	7.576	-2.219	4.212e-02	0.369	-3.963	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	4	124537405, 124540132	BF508662	10252	4q28.1	Hs.436944	15	ureteric bud development induction of an organ protein binding cytoplasm cytosol plasma membrane multicellular organismal development regulation of signal transduction lamellipodium negative regulation of MAP kinase activity	Jak-STAT signaling pathway
208594_x_at	0.331	4.780	2.219	4.213e-02	0.369	-3.964	LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	19	-59432280	NM_024318	79168	19q13.4	Hs.688335	6	receptor activity immune response membrane integral to membrane
203103_s_at	-0.249	7.068	-2.218	4.216e-02	0.369	-3.964	PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)	11	-60414596	NM_014502	27339	11q12.2	Hs.502705	22	ubiquitin ligase complex protein polyubiquitination inner cell mass cell proliferation DNA binding ubiquitin-protein ligase activity protein binding nucleus nucleoplasm spliceosomal complex cytoplasm lipid particle DNA repair mRNA processing response to DNA damage stimulus RNA splicing lipid biosynthetic process negative regulation of neuron differentiation positive regulation of astrocyte differentiation	Ubiquitin mediated proteolysis
212760_at	-0.388	8.644	-2.218	4.216e-02	0.369	-3.964	UBR2	ubiquitin protein ligase E3 component n-recognin 2	6	42640035	AB002347	23304	6p21.1	Hs.529925	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus ubiquitin-dependent protein catabolic process male meiosis I spermatogenesis zinc ion binding ligase activity protein catabolic process metal ion binding
213128_s_at	-0.513	8.400	-2.218	4.216e-02	0.369	-3.964	UBE3A	ubiquitin protein ligase E3A	15	-23133488, -23133488, -23133488	AA527499	7337	15q11-q13	Hs.598862	76	ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms	Ubiquitin mediated proteolysis
226528_at	-0.424	7.599	-2.218	4.217e-02	0.369	-3.965	MTX3	metaxin 3	5	-79308294	AI743044	345778	5q14.1	Hs.531418	3	mitochondrion mitochondrial outer membrane protein targeting to mitochondrion protein transport membrane
220052_s_at	-0.251	5.965	-2.218	4.218e-02	0.369	-3.965	TINF2	TERF1 (TRF1)-interacting nuclear factor 2	14	-23778690	NM_012461	26277	14q12	Hs.496191	30	chromosome, telomeric region nuclear telomere cap complex DNA binding nucleus nucleoplasm chromosome protein C-terminus binding perinucleolar chromocenter telomere maintenance via telomere lengthening negative regulation of protein amino acid ADP-ribosylation telomere assembly positive regulation of telomere maintenance negative regulation of telomere maintenance via telomerase negative regulation of telomere maintenance via telomerase telomeric DNA binding negative regulation of epithelial cell proliferation protein localization to telomere
229835_s_at	0.416	5.662	2.218	4.219e-02	0.369	-3.965	SLMO2	slowmo homolog 2 (Drosophila)	20	-57041594	AA004210	51012	20q13.32	Hs.719250	5
202544_at	-0.394	6.593	-2.218	4.220e-02	0.369	-3.965	GMFB	glia maturation factor, beta	14	-54010958	NM_004124	2764	14q22.2	Hs.151413	10	actin binding protein kinase inhibitor activity signal transducer activity intracellular protein amino acid phosphorylation signal transduction nervous system development enzyme activator activity growth factor activity
223399_x_at	0.272	4.773	2.218	4.221e-02	0.369	-3.965	PBRM1	polybromo 1	3	-52554407, -52554407	AF197569	55193	3p21	Hs.189920	19	nuclear chromosome DNA binding chromatin binding protein binding nucleus chromatin remodeling mitosis regulation of transcription
228185_at	-0.400	7.338	-2.217	4.224e-02	0.369	-3.966	ZNF25	zinc finger protein 25	10	-38278800	N32599	219749	10p11.1	Hs.499429	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207467_x_at	-0.457	8.802	-2.217	4.227e-02	0.369	-3.967	CAST	calpastatin	5	96023696, 96064251, 96104999	NM_001750	831	5q15	Hs.436186	60	protein binding calcium-dependent cysteine-type endopeptidase inhibitor activity
229115_at	-0.546	6.652	-2.217	4.227e-02	0.369	-3.967	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	14	101500617	BF000332	1778	14q32 14q32.3-qter	Hs.649497	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm Golgi apparatus cytoplasmic dynein complex microtubule microtubule-based movement mitotic spindle organization ATPase activity, coupled
223625_at	-0.380	5.760	-2.217	4.228e-02	0.369	-3.967	FAM126A	family with sequence similarity 126, member A	7	-22947402	AB030241	84668	7p15.3	Hs.85603	9	signal transducer activity cellular_component cytoplasm biological_process membrane
203261_at	-0.213	8.809	-2.217	4.228e-02	0.369	-3.967	DCTN6	dynactin 6	8	30133354	NM_006571	10671	8p12-p11	Hs.146585	6	cytoplasm cytoskeleton dynactin complex transferase activity dynein binding
221563_at	-0.702	7.047	-2.217	4.228e-02	0.369	-3.967	DUSP10	dual specificity phosphatase 10	1	-219941388, -219941388	N36770	11221	1q41	Hs.497822	15	protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation response to stress JNK cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
212832_s_at	-0.214	7.957	-2.217	4.229e-02	0.369	-3.967	CKAP5	cytoskeleton associated protein 5	11	-46721659	AI143124	9793	11p11.2	Hs.201253	16	gamma-tubulin complex protein binding centrosome cell cycle mitosis microtubule cytoskeleton establishment or maintenance of microtubule cytoskeleton polarity RNA transport centrosome organization spindle pole body organization cell division
50400_at	0.214	4.793	2.217	4.229e-02	0.369	-3.967	PAOX	polyamine oxidase (exo-N4-amino)	10	135042730	AI743990	196743	10q26.3	Hs.532469	8
242722_at	-0.402	6.194	-2.217	4.230e-02	0.369	-3.967	LMO7	LIM domain 7	13	75092570, 75232797	AA100793	4008	13q22.2	Hs.207631	18	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm zinc ion binding protein ubiquitination metal ion binding	Adherens junction
208959_s_at	-0.281	7.152	-2.216	4.231e-02	0.369	-3.967	ERP44	endoplasmic reticulum protein 44	9	-101781283	BC005374	23071	9q31.1	Hs.154023	17	protein disulfide isomerase activity protein binding endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum membrane ER-Golgi intermediate compartment protein folding response to unfolded protein glycoprotein metabolic process cell redox homeostasis
216468_s_at	0.464	2.068	2.216	4.232e-02	0.369	-3.968	ZNF682	zinc finger protein 682	19	-19976226, -19976226	AC006539	91120	19p12	Hs.306298	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201386_s_at	-0.404	7.290	-2.216	4.232e-02	0.369	-3.968	DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	4	-24138185	AF279891	1665	4p15.3	Hs.696074	9	nucleotide binding nucleic acid binding RNA helicase activity ATP binding nucleus U12-type spliceosomal complex mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity
220665_at	0.268	5.394	2.216	4.233e-02	0.369	-3.968	LUZP4	leucine zipper protein 4	X	114430547	NM_016383	51213	Xq23	Hs.242183	4	nucleus
1553279_at	0.369	6.739	2.216	4.237e-02	0.369	-3.969	BTNL9	butyrophilin-like 9	5	180399830	NM_152547	153579	5q35.3	Hs.546502	4	membrane integral to membrane
202897_at	-0.363	5.647	-2.216	4.237e-02	0.369	-3.969	SIRPA	signal-regulatory protein alpha	20	1822812, 1823424, 1823825	AB023430	140885	20p13	Hs.581021 Hs.679042	53	plasma membrane plasma membrane cell adhesion integral to membrane SH3 domain binding
225413_at	0.208	12.233	2.216	4.238e-02	0.369	-3.969	USMG5	up-regulated during skeletal muscle growth 5 homolog (mouse)	10	-105138803	BG291685	84833	10q24.33	Hs.500921	5	mitochondrion mitochondrial inner membrane membrane integral to membrane
221489_s_at	0.248	6.113	2.216	4.238e-02	0.369	-3.969	SPRY4	sprouty homolog 4 (Drosophila)	5	-141670175	W48843	81848	5q31.3	Hs.323308	14	protein binding cytoplasm plasma membrane multicellular organismal development regulation of signal transduction cell projection negative regulation of MAP kinase activity	Jak-STAT signaling pathway
220650_s_at	0.240	5.813	2.215	4.239e-02	0.369	-3.969	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5	16	65840355	NM_004594	6553	16q22.1	Hs.439650	11	cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane sodium ion binding
204076_at	-0.473	7.387	-2.215	4.245e-02	0.370	-3.970	ENTPD4	ectonucleoside triphosphate diphosphohydrolase 4	8	-23345516, -23345516	AB002390	9583	8p21.3-p21.2	Hs.444389	8	magnesium ion binding calcium ion binding Golgi apparatus UDP catabolic process membrane integral to membrane hydrolase activity integral to Golgi membrane cytoplasmic vesicle uridine-diphosphatase activity	Purine metabolism Pyrimidine metabolism Lysosome
211663_x_at	0.590	7.375	2.215	4.246e-02	0.370	-3.970	PTGDS	prostaglandin D2 synthase 21kDa (brain)	9	138991776	M61900	5730	9q34.2-q34.3	Hs.446429	63	prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm	Arachidonic acid metabolism Metabolic pathways
220048_at	0.226	5.888	2.214	4.247e-02	0.370	-3.971	EDAR	ectodysplasin A receptor	2	-108877358	NM_022336	10913	2q11-q13	Hs.171971	23	hair follicle development transmembrane receptor activity protein binding plasma membrane apoptosis signal transduction multicellular organismal development salivary gland development integral to membrane cell differentiation positive regulation of NF-kappaB import into nucleus odontogenesis of dentine-containing tooth pigmentation apical part of cell	Cytokine-cytokine receptor interaction
210304_at	0.245	5.012	2.214	4.248e-02	0.370	-3.971	PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta	4	609362, 636965	BC000249	5158	4p16.3	Hs.623810 Hs.654544	30	signal transduction visual perception phototransduction, visible light detection of light stimulus membrane hydrolase activity 3',5'-cyclic-GMP phosphodiesterase activity response to stimulus
205745_x_at	-0.222	5.430	-2.214	4.248e-02	0.370	-3.971	ADAM17	ADAM metallopeptidase domain 17	2	-9546861	NM_003183	6868	2p25	Hs.404914	121	response to hypoxia positive regulation of protein amino acid phosphorylation neutrophil mediated immunity germinal center formation metalloendopeptidase activity interleukin-6 receptor binding integrin binding protein binding cytoplasm integral to plasma membrane cell-cell junction focal adhesion proteolysis epidermal growth factor receptor signaling pathway Notch signaling pathway peptidase activity zinc ion binding positive regulation of cell proliferation response to bacterium cell surface positive regulation of T cell chemotaxis actin cytoskeleton membrane apical plasma membrane SH3 domain binding PDZ domain binding B cell differentiation positive regulation of cell growth positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of cyclin-dependent protein kinase activity during G1/S response to lipopolysaccharide ruffle membrane negative regulation of interleukin-8 production positive regulation of chemokine production regulation of mast cell apoptosis T cell differentiation in the thymus cell adhesion mediated by integrin wound healing, spreading of epidermal cells response to drug membrane raft positive regulation of epidermal growth factor receptor activity metal ion binding spleen development cell motility PMA-inducible membrane protein ectodomain proteolysis response to high density lipoprotein stimulus	Notch signaling pathway Alzheimer's disease Epithelial cell signaling in Helicobacter pylori infection
220309_at	0.320	3.567	2.214	4.248e-02	0.370	-3.971	TTC22	tetratricopeptide repeat domain 22	1	-55022811, -55019339	NM_017904	55001	1p32.3	Hs.16230	3	binding
213355_at	-1.052	6.136	-2.214	4.248e-02	0.370	-3.971	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	3	99934261	AI989567	10402	3q12.1	Hs.148716	5	Golgi apparatus amino sugar metabolic process protein amino acid glycosylation glycolipid metabolic process sialyltransferase activity protein lipoylation membrane integral to membrane integral to Golgi membrane	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
222401_s_at	-0.343	8.202	-2.214	4.249e-02	0.370	-3.971	TMEM50A	transmembrane protein 50A	1	25537397	AL550722	23585	1p36.11	Hs.523054	13	cytoplasm endoplasmic reticulum membrane integral to membrane
204646_at	0.374	6.084	2.214	4.250e-02	0.370	-3.971	DPYD	dihydropyrimidine dehydrogenase	1	-97957902, -97315887	NM_000110	1806	1p22	Hs.335034	100	dihydroorotate oxidase activity dihydrouracil dehydrogenase (NAD+) activity binding iron ion binding cytoplasm cytosol cytosol purine base catabolic process 'de novo' pyrimidine base biosynthetic process thymine catabolic process uracil catabolic process thymidine catabolic process UMP biosynthetic process electron carrier activity oxidoreductase activity dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity protein homodimerization activity protein homodimerization activity metal ion binding FAD binding NADP or NADPH binding 4 iron, 4 sulfur cluster binding oxidation reduction	Pyrimidine metabolism beta-Alanine metabolism Pantothenate and CoA biosynthesis Drug metabolism - other enzymes Metabolic pathways
229109_s_at	0.212	5.161	2.214	4.251e-02	0.370	-3.972	BLVRA	biliverdin reductase A	7	43764796	N21095	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
225464_at	-0.656	6.457	-2.214	4.251e-02	0.370	-3.972	FRMD6	FERM domain containing 6	14	51025604, 51188325	N30138	122786	14q22.1	Hs.434914	9	binding cytoplasm mitochondrion cytoskeleton plasma membrane
210381_s_at	0.336	5.282	2.214	4.252e-02	0.370	-3.972	CCKBR	cholecystokinin B receptor	11	6237541	BC000740	887	11p15.4	Hs.203	74	phosphoinositide phospholipase C activity receptor activity G-protein coupled receptor activity protein binding membrane fraction plasma membrane integral to plasma membrane activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration digestion sensory perception feeding behavior positive regulation of cell proliferation gastrin receptor activity 1-phosphatidylinositol-3-kinase regulator activity	Calcium signaling pathway Neuroactive ligand-receptor interaction
223740_at	0.261	5.740	2.214	4.252e-02	0.370	-3.972	C6orf59	chromosome 6 open reading frame 59	6	-161501163	AL136708	79992	6q26	Hs.664873	5
234647_at	0.269	6.605	2.213	4.255e-02	0.370	-3.972	KCNIP3	Kv channel interacting protein 3, calsenilin	2	95326798, 95376494	AK026052	30818	2q21.1	Hs.437376	43	negative regulation of transcription from RNA polymerase II promoter DNA binding transcription corepressor activity voltage-gated ion channel activity potassium channel activity calcium ion binding nucleus cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane ion transport potassium ion transport apoptosis signal transduction behavior protein C-terminus binding specific transcriptional repressor activity sensory perception of pain potassium ion binding regulation of neuron apoptosis regulation of transcription response to pain calcium-dependent protein binding
235104_at	-0.546	4.216	-2.213	4.257e-02	0.370	-3.973	ERAP2	endoplasmic reticulum aminopeptidase 2	5	96237399	BG292389	64167	5q15	Hs.482910	14	aminopeptidase activity endoplasmic reticulum endoplasmic reticulum lumen proteolysis immune response regulation of blood pressure peptidase activity metallopeptidase activity zinc ion binding membrane integral to membrane antigen processing and presentation of endogenous peptide antigen via MHC class I metal ion binding
219081_at	-0.666	6.824	-2.213	4.257e-02	0.370	-3.973	ANKHD1	ankyrin repeat and KH domain containing 1	5	139761612, 139761612	NM_024668	54882	5q31.3	Hs.594084	12	RNA binding protein binding cytoplasm
1558119_at	0.246	4.851	2.213	4.260e-02	0.370	-3.973	TSPAN17	tetraspanin 17	5	176006993	BG769410	26262	5q35.3	Hs.532129	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding membrane integral to membrane protein ubiquitination
225765_at	-0.252	6.870	-2.213	4.261e-02	0.370	-3.974	TNPO1	transportin 1	5	72148173, 72179685	AA527296	3842	5q13.2	Hs.482497	58	protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
205984_at	0.394	3.481	2.213	4.261e-02	0.370	-3.974	CRHBP	corticotropin releasing hormone binding protein	5	76284435	NM_001882	1393	5q11.2-q13.3	Hs.115617	31	protein binding extracellular space soluble fraction signal transduction female pregnancy learning or memory adrenocorticotropin-releasing hormone binding hormone metabolic process
228109_at	0.269	6.056	2.212	4.263e-02	0.370	-3.974	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2	5	80292313	AI912976	5924	5q13	Hs.162129	11	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular cytoplasm endoplasmic reticulum plasma membrane regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway
231953_at	-0.533	3.666	-2.212	4.264e-02	0.370	-3.974	BPTF	bromodomain PHD finger transcription factor	17	63252241	AK027184	2186	17q24.3	Hs.444200	22	negative regulation of transcription from RNA polymerase II promoter nucleus cytoplasm chromatin remodeling brain development DNA-dependent ATPase activity transcription factor binding zinc ion binding transcription regulator activity positive regulation of gene-specific transcription sequence-specific DNA binding sequence-specific DNA binding regulation of transcription metal ion binding
207675_x_at	0.244	4.688	2.212	4.266e-02	0.370	-3.975	ARTN	artemin	1	44171578, 44173617, 44174240	NM_003976	9048	1p33-p32	Hs.632404	14	extracellular region signal transduction neuroblast proliferation growth factor activity
229292_at	-0.257	4.599	-2.212	4.268e-02	0.370	-3.975	EPB41L5	erythrocyte membrane protein band 4.1 like 5	2	120487138	AI652872	57669	2q14.2	Hs.654802	5	binding cytoplasm cytoskeleton adherens junction cytoskeletal protein binding extrinsic to membrane cell junction
202480_s_at	-0.394	5.888	-2.212	4.269e-02	0.370	-3.975	DEDD	death effector domain containing	1	-159357391, -159357391	NM_004216	9191	1q23.3	Hs.146406	13	DNA binding protein binding nucleus nucleolus cytoplasm induction of apoptosis spermatogenesis induction of apoptosis via death domain receptors negative regulation of transcription regulation of apoptosis
202844_s_at	-0.287	7.653	-2.212	4.270e-02	0.370	-3.975	RALBP1	ralA binding protein 1	18	9465529	AW025261	10928	18p11.3	Hs.528993 Hs.719181	42	GTPase activator activity protein binding intracellular transport chemotaxis signal transduction small GTPase mediated signal transduction membrane ATPase activity Ral GTPase binding Rac GTPase activator activity regulation of GTPase activity positive regulation of Cdc42 GTPase activity ATPase activity, coupled to movement of substances Rac GTPase binding	Pathways in cancer Pancreatic cancer
209124_at	0.338	6.129	2.211	4.272e-02	0.370	-3.976	MYD88	myeloid differentiation primary response gene (88)	3	38154972	U70451	4615	3p22	Hs.82116	98	response to molecule of fungal origin MyD88-dependent toll-like receptor signaling pathway transmembrane receptor activity Toll binding death receptor binding protein binding cytoplasm inflammatory response Toll signaling pathway response to virus immunoglobulin mediated immune response cytokine-mediated signaling pathway intrinsic to membrane lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide positive regulation of tumor necrosis factor production regulation of cell proliferation positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of chemokine biosynthetic process innate immune response type I interferon biosynthetic process positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade positive regulation of smooth muscle cell proliferation positive regulation of NF-kappaB transcription factor activity	Apoptosis Toll-like receptor signaling pathway
219347_at	-0.420	6.619	-2.211	4.275e-02	0.370	-3.976	NUDT15	nudix (nucleoside diphosphate linked moiety X)-type motif 15	13	47509703	NM_018283	55270	13q14.2	Hs.144407	5	magnesium ion binding hydrolase activity manganese ion binding
208385_at	0.275	4.801	2.211	4.275e-02	0.370	-3.977	NR2E3	nuclear receptor subfamily 2, group E, member 3	15	69889947, 69889947	NM_016346	10002	15q22.32	Hs.187354	23	transcription factor activity steroid hormone receptor activity steroid binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter signal transduction visual perception phototransduction zinc ion binding sequence-specific DNA binding metal ion binding response to stimulus
1557615_a_at	0.287	3.847	2.211	4.276e-02	0.370	-3.977	SLIT1	slit homolog 1 (Drosophila)	10	-98747784	AA431797	6585	10q23.3-q24	Hs.632082	16	calcium ion binding protein binding extracellular region extracellular space multicellular organismal development nervous system development brain development cell differentiation retinal ganglion cell axon guidance establishment of nucleus localization intracellular membrane-bounded organelle	Axon guidance
1552485_at	-0.480	5.443	-2.211	4.276e-02	0.370	-3.977	LACTB	lactamase, beta	15	61201084, 61201084	NM_171846	114294	15q22.1	Hs.410388	10	mitochondrion hydrolase activity
207602_at	0.262	5.068	2.211	4.276e-02	0.370	-3.977	TMPRSS11D	transmembrane protease, serine 11D	4	-68369188	NM_004262	9407	4q13.2	Hs.132195	11	serine-type endopeptidase activity extracellular region plasma membrane integral to plasma membrane proteolysis respiratory gaseous exchange peptidase activity
220233_at	0.300	5.404	2.211	4.277e-02	0.370	-3.977	FBXO17	F-box protein 17	19	-44123881, -44123881	NM_024907	115290	19q13.2	Hs.531770	7	protein binding modification-dependent protein catabolic process protein catabolic process
215138_s_at	0.258	6.141	2.211	4.278e-02	0.370	-3.977	RP1-21O18.1	kazrin	1	14797799, 14797799, 15123211, 15128882, 15145001	AB015329	23254	1p36.21	Hs.368823	10	nucleus cytoplasm cytoskeleton cell junction desmosome keratinization
225566_at	0.367	4.850	2.211	4.278e-02	0.370	-3.977	NRP2	neuropilin 2	2	206255468, 206255468, 206255468	AI819729	8828	2q33.3	Hs.471200	44	receptor activity vascular endothelial growth factor receptor activity membrane fraction plasma membrane cell adhesion multicellular organismal development nervous system development axon guidance integral to membrane cell differentiation
216480_x_at	0.203	2.796	2.211	4.279e-02	0.370	-3.977	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10	21863107, 21863579	AF060927	8028	10p12	Hs.30385	19	transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding
214242_at	0.234	4.748	2.210	4.280e-02	0.370	-3.977	MAN1A2	mannosidase, alpha, class 1A, member 2	1	117711607	AI189305	10905	1p13	Hs.435938	25	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding membrane fraction Golgi apparatus N-glycan processing metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds	N-Glycan biosynthesis Metabolic pathways
200846_s_at	-0.328	8.856	-2.210	4.281e-02	0.370	-3.978	PPP1CA	protein phosphatase 1, catalytic subunit, alpha isoform	11	-66922227	NM_002708	5499	11q13	Hs.183994	83	protein serine/threonine phosphatase activity iron ion binding protein binding nucleoplasm cytoplasm carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding lung development neuron projection ribonucleoprotein binding cell soma metal ion binding branching morphogenesis of a tube cell division MLL5-L complex	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton Insulin signaling pathway
210423_s_at	0.274	4.968	2.210	4.282e-02	0.370	-3.978	SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	2	218954995	L32185	6556	2q35	Hs.591607	106	transporter activity iron ion binding vacuole plasma membrane integral to plasma membrane ion transport iron ion transport cellular cadmium ion homeostasis cellular iron ion homeostasis response to bacterium phagocytic vesicle membrane protein homodimerization activity transition metal ion transmembrane transporter activity metal ion:hydrogen antiporter activity cadmium ion transmembrane transport	Lysosome
207305_s_at	-0.379	8.718	-2.210	4.282e-02	0.370	-3.978	KIAA1012	KIAA1012	18	-27663133	NM_014939	22878	18q12.1	Hs.202001	8	Golgi apparatus cis-Golgi network ER to Golgi vesicle-mediated transport vesicle-mediated transport
219689_at	0.642	6.378	2.210	4.285e-02	0.370	-3.978	SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	3	-52442307	NM_020163	56920	3p21.1	Hs.59729	6	receptor activity extracellular region multicellular organismal development membrane	Axon guidance
208394_x_at	0.306	3.497	2.210	4.286e-02	0.370	-3.979	ESM1	endothelial cell-specific molecule 1	5	-54309452	NM_007036	11082	5q11.2	Hs.129944	15	regulation of cell growth protein binding insulin-like growth factor binding extracellular region growth factor activity biological_process
233836_at	0.298	6.106	2.210	4.287e-02	0.370	-3.979	TNRC6A	trinucleotide repeat containing 6A	16	24648549	AK025277	27327	16p11.2	Hs.655057	28	nucleotide binding cytoplasmic mRNA processing body RNA binding cytoplasm regulation of translation gene silencing by RNA micro-ribonucleoprotein complex gene silencing by miRNA, negative regulation of translation
220380_at	0.200	4.012	2.210	4.287e-02	0.370	-3.979	DNASE2B	deoxyribonuclease II beta	1	84636802, 84646621	NM_021233	58511	1p22.3	Hs.129142	5	endodeoxyribonuclease activity deoxyribonuclease II activity extracellular region cytoplasm lysosome DNA metabolic process hydrolase activity	Lysosome
229208_at	-0.445	3.840	-2.209	4.291e-02	0.370	-3.980	HAUS2	HAUS augmin-like complex, subunit 2	15	40628302	AK022939	55142	15q15.2	Hs.14347	9	centrosome spindle microtubule cell cycle mitosis cell division HAUS complex
218639_s_at	0.292	6.765	2.209	4.293e-02	0.370	-3.980	ZXDC	ZXD family zinc finger C	3	-127652648, -127639133	NM_025112	79364	3q21.3	Hs.440049 Hs.711046	8	nucleic acid binding transcription factor activity intracellular nucleus zinc ion binding transcription activator activity LRR domain binding identical protein binding positive regulation of transcription metal ion binding C2H2 zinc finger domain binding
207921_x_at	0.303	5.180	2.209	4.295e-02	0.370	-3.980	PAX8	paired box 8	2	-113690044	NM_013952	7849	2q12-q14	Hs.469728	55	transcription factor activity thyroid-stimulating hormone receptor activity protein binding nucleus nucleoplasm multicellular organismal development anatomical structure morphogenesis transcription activator activity cell differentiation regulation of transcription positive regulation of transcription, DNA-dependent	Pathways in cancer Thyroid cancer
239314_at	0.230	3.495	2.209	4.295e-02	0.370	-3.981	NHLRC3	NHL repeat containing 3	13	38510454	AV688972	387921	13q13.3	Hs.507783	1	extracellular region
214335_at	0.300	6.402	2.208	4.296e-02	0.370	-3.981	RPL18	ribosomal protein L18	19	-53810399	AI669349	6141	19q13	Hs.515517	16	RNA binding structural constituent of ribosome intracellular cytoplasm cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
202512_s_at	-0.413	6.611	-2.208	4.297e-02	0.370	-3.981	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	6	-106739044	NM_004849	9474	6q21	Hs.486063	30	autophagic vacuole formation protein binding cytoplasm autophagic vacuole autophagy apoptosis pre-autophagosomal structure membrane post-translational protein modification	Regulation of autophagy RIG-I-like receptor signaling pathway
203000_at	0.274	3.968	2.208	4.299e-02	0.370	-3.981	STMN2	stathmin-like 2	8	80685934	BF967657	11075	8q21.13	Hs.521651	23	protein binding membrane fraction soluble fraction cytoplasm intracellular signaling cascade membrane neuron differentiation axon growth cone cell projection perinuclear region of cytoplasm
242336_at	-0.314	2.787	-2.208	4.299e-02	0.370	-3.981	GSK3B	glycogen synthase kinase 3 beta	3	-121023493	R51305	2932	3q13.3	Hs.445733 Hs.593022	373	nucleotide binding re-entry into mitotic cell cycle p53 binding glycogen synthase kinase 3 activity ATP binding nucleus cytoplasm cytosol cytosol glycogen metabolic process anti-apoptosis response to stress ER overload response intracellular signaling cascade beta-catenin binding organ morphogenesis transferase activity peptidyl-serine phosphorylation growth cone beta-catenin destruction complex positive regulation of protein complex assembly protein kinase A catalytic subunit binding Axin-APC-beta-catenin-GSK3B complex cell soma dendritic shaft membrane-bounded organelle fat cell differentiation positive regulation of protein export from nucleus tau-protein kinase activity NF-kappaB binding Wnt receptor signaling pathway through beta-catenin	ErbB signaling pathway Chemokine signaling pathway Cell cycle Wnt signaling pathway Hedgehog signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Insulin signaling pathway Melanogenesis Alzheimer's disease Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Basal cell carcinoma
229702_at	0.209	4.942	2.208	4.300e-02	0.370	-3.982	CSNK1G3	casein kinase 1, gamma 3	5	122875691	BF516404	1456	5q23	Hs.129206	6	nucleotide binding protein serine/threonine kinase activity ATP binding cytoplasm protein modification process protein amino acid phosphorylation signal transduction Wnt receptor signaling pathway transferase activity	Hedgehog signaling pathway
202178_at	-0.219	4.146	-2.208	4.300e-02	0.370	-3.982	PRKCZ	protein kinase C, zeta	1	1971768, 1994945, 2026014	NM_002744	5590	1p36.33-p36.2	Hs.496255	206	nucleotide binding protein kinase C activity ATP binding membrane fraction cytoplasm endosome plasma membrane anti-apoptosis intracellular signaling cascade zinc ion binding transferase activity peptidyl-serine phosphorylation diacylglycerol binding negative regulation of protein complex assembly insulin receptor substrate binding negative regulation of insulin receptor signaling pathway metal ion binding negative regulation of peptidyl-tyrosine phosphorylation	Chemokine signaling pathway Endocytosis Tight junction Insulin signaling pathway Type II diabetes mellitus
231967_at	-0.319	4.128	-2.208	4.302e-02	0.370	-3.982	PHF20L1	PHD finger protein 20-like 1	8	133856785, 133856785, 133856785	AI913146	51105	8q24.22	Hs.304362	4	nucleic acid binding protein binding zinc ion binding metal ion binding
220970_s_at	0.286	3.445	2.208	4.302e-02	0.370	-3.982	KRTAP2-4	keratin associated protein 2-4	17	-36474894, 287342	NM_030977	85294	17q12-q21	Hs.560502	3	keratin filament
200700_s_at	-0.524	7.998	-2.208	4.303e-02	0.370	-3.982	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	7	-6467236	NM_006854	11014	7p22.1	Hs.654552 Hs.705873	12	receptor activity KDEL sequence binding protein binding endoplasmic reticulum Golgi apparatus protein retention in ER lumen intracellular protein transport membrane integral to membrane vesicle-mediated transport	Vibrio cholerae infection
234929_s_at	0.256	5.536	2.208	4.304e-02	0.370	-3.982	SPATA7	spermatogenesis associated 7	14	87921764	AF144488	55812	14q31.3	Hs.525518	12	visual perception response to stimulus
205858_at	0.249	4.680	2.207	4.305e-02	0.370	-3.982	NGFR	nerve growth factor receptor (TNFR superfamily, member 16)	17	44927653	NM_002507	4804	17q21-q22	Hs.415768 Hs.681726	126	neurotrophin receptor activity death receptor activity protein binding nucleus cytoplasm plasma membrane integral to plasma membrane apoptosis induction of apoptosis signal transduction multicellular organismal development axon guidance central nervous system development response to wounding regulation of gene expression detection of temperature stimulus nerve development cell differentiation hair follicle morphogenesis negative regulation of fibroblast growth factor receptor signaling pathway positive regulation of odontogenesis of dentine-containing tooth skin development positive regulation of fibroblast proliferation nerve growth factor binding negative regulation of muscle development negative regulation of hair follicle development	Cytokine-cytokine receptor interaction Neurotrophin signaling pathway
242272_at	0.274	5.954	2.207	4.305e-02	0.370	-3.983	ZNF785	zinc finger protein 785	16	-30499494	AI375066	146540	16p11.2	Hs.513509	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552930_at	0.306	5.337	2.207	4.306e-02	0.370	-3.983	MMEL1	membrane metallo-endopeptidase-like 1	1	-2511940	NM_033467	79258	1p36	Hs.591453	10	metalloendopeptidase activity extracellular region proteolysis peptidase activity zinc ion binding membrane integral to membrane intracellular membrane-bounded organelle metal ion binding
202050_s_at	-0.272	7.009	-2.207	4.306e-02	0.370	-3.983	ZMYM4	zinc finger, MYM-type 4	1	35507154	AI650586	9202	1p32-p34	Hs.269211	7	DNA binding nucleus multicellular organismal development zinc ion binding metal ion binding
213358_at	-0.469	5.415	-2.207	4.307e-02	0.370	-3.983	KIAA0802	KIAA0802	18	8707368	AB018345	23255	18p11.22	Hs.650822	10
226776_at	-0.800	6.247	-2.207	4.309e-02	0.371	-3.983	ENY2	enhancer of yellow 2 homolog (Drosophila)	8	110415811	BF433516	56943	8q23.1	Hs.492555	5	SAGA complex nucleus transport chromatin modification histone deubiquitination ligand-dependent nuclear receptor transcription coactivator activity regulation of transcription positive regulation of transcription, DNA-dependent mRNA transport
206164_at	0.307	4.633	2.207	4.311e-02	0.371	-3.984	CLCA2	chloride channel accessory 2	1	86662356	NM_006536	9635	1p31-p22	Hs.241551	18	chloride channel activity calcium ion binding protein binding extracellular region plasma membrane integral to plasma membrane ion transport chloride transport cell adhesion ligand-gated ion channel activity cell junction chloride ion binding	Olfactory transduction
213244_at	0.187	5.461	2.206	4.313e-02	0.371	-3.984	SCAMP4	secretory carrier membrane protein 4	19	1856372	AI207792	113178	19p13.3	Hs.144980	6	protein transport membrane integral to membrane
225105_at	1.874	8.723	2.206	4.314e-02	0.371	-3.984	C12orf75	chromosome 12 open reading frame 75	12	104248543	BF969397	387882	12q23.3	Hs.368938	3
202956_at	-0.334	6.510	-2.206	4.315e-02	0.371	-3.985	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	8	-68272450	NM_006421	10565	8q13	Hs.656902	22	ARF guanyl-nucleotide exchange factor activity binding intracellular exocytosis ARF GTPase activator activity myosin binding regulation of ARF protein signal transduction
211855_s_at	-0.334	5.488	-2.206	4.316e-02	0.371	-3.985	SLC25A14	solute carrier family 25 (mitochondrial carrier, brain), member 14	X	129301727	AF155810	9016	Xq24	Hs.194686	13	binding mitochondrion mitochondrial inner membrane integral to plasma membrane transport mitochondrial transport aerobic respiration membrane
236112_at	0.282	3.294	2.206	4.316e-02	0.371	-3.985	LOC285548	hypothetical LOC285548	4	-13156797	AI632413	285548	4p15.33	Hs.529284 Hs.698223	1
227916_x_at	-0.320	6.032	-2.206	4.317e-02	0.371	-3.985	EXOSC3	exosome component 3	9	-37770307, -37770307	AA747303	51010	9p11	Hs.602571 Hs.713483	12	3'-5'-exoribonuclease activity nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing hydrolase activity	RNA degradation
1569140_at	-0.320	2.946	-2.206	4.319e-02	0.371	-3.985	UBR2	ubiquitin protein ligase E3 component n-recognin 2	6	42640035	BC024217	23304	6p21.1	Hs.529925	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus ubiquitin-dependent protein catabolic process male meiosis I spermatogenesis zinc ion binding ligase activity protein catabolic process metal ion binding
243612_at	0.333	4.969	2.206	4.319e-02	0.371	-3.985	NSD1	nuclear receptor binding SET domain protein 1	5	176492685, 176493438	AL526448	64324	5q35.2-q35.3	Hs.106861	36	negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription corepressor activity protein binding nucleus methyltransferase activity zinc ion binding chromatin modification histone methylation transferase activity ligand-dependent nuclear receptor binding estrogen receptor binding histone methyltransferase activity (H4-K20 specific) regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	Lysine degradation
227455_at	0.364	7.070	2.205	4.322e-02	0.371	-3.986	C6orf136	chromosome 6 open reading frame 136	6	30722794, 2063373, 1861669	BF224092	221545	6p21.33	Hs.591787	7
219072_at	0.270	7.336	2.205	4.323e-02	0.371	-3.986	BCL7C	B-cell CLL/lymphoma 7C	16	-30806616	NM_004765	9274	16p11	Hs.658547	9	apoptosis
235155_at	0.387	3.764	2.205	4.326e-02	0.371	-3.987	BDH2	3-hydroxybutyrate dehydrogenase, type 2	4	-104218230	AW136198	56898	4q24	Hs.124696	7	3-hydroxybutyrate dehydrogenase activity binding cytoplasm mitochondrion fatty acid beta-oxidation oxidoreductase activity NAD or NADH binding oxidation reduction	Synthesis and degradation of ketone bodies Butanoate metabolism Metabolic pathways
210187_at	0.376	4.341	2.205	4.327e-02	0.371	-3.987	FKBP1A	FK506 binding protein 1A, 12kDa	20	-1300360, -1297622	BC005147	2280	20p13	Hs.471933 Hs.700839	82	peptidyl-prolyl cis-trans isomerase activity signal transducer activity transforming growth factor beta receptor activity ryanodine-sensitive calcium-release channel activity FK506 binding FK506 binding cytoplasm cytosol 'de novo' protein folding SMAD protein complex assembly terminal cisterna isomerase activity protein maturation by protein folding positive regulation of protein ubiquitination positive regulation of protein binding negative regulation of protein phosphatase type 2B activity regulation of activin receptor signaling pathway beta-amyloid formation type I transforming growth factor beta receptor binding protein refolding T cell activation positive regulation of I-kappaB kinase/NF-kappaB cascade fibril organization SMAD binding activin binding regulation of immune response ventricular cardiac muscle morphogenesis regulation of ryanodine-sensitive calcium-release channel activity regulation of ryanodine-sensitive calcium-release channel activity heart trabecula formation
204215_at	0.425	5.143	2.204	4.331e-02	0.371	-3.988	C7orf23	chromosome 7 open reading frame 23	7	-86663413	NM_024315	79161	7q21.1-q21.2	Hs.719226	4	membrane integral to membrane
228825_at	0.380	5.752	2.204	4.332e-02	0.371	-3.988	PTGR1	prostaglandin reductase 1	9	-113365069, -113365069, -113351823	BE566894	22949	9q31.3	Hs.584864	7	alcohol dehydrogenase (NAD) activity binding cytoplasm leukotriene metabolic process zinc ion binding oxidoreductase activity 2-alkenal reductase activity 15-oxoprostaglandin 13-oxidase activity oxidation reduction
225307_at	-0.356	7.969	-2.204	4.336e-02	0.371	-3.989	ZNF511	zinc finger protein 511	10	134972412	AL583632	118472	10q26.3	Hs.422113	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
210331_at	0.226	4.914	2.204	4.336e-02	0.371	-3.989	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	7	43118722	AB048365	23072	7p14.1-p13	Hs.164453	8	protein binding intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process
207938_at	0.280	4.614	2.203	4.338e-02	0.371	-3.989	PI15	peptidase inhibitor 15	8	75899326	NM_015886	51050	8q21.11	Hs.98558	6	extracellular region biological_process peptidase inhibitor activity
217099_s_at	0.280	5.917	2.203	4.340e-02	0.372	-3.990	GEMIN4	gem (nuclear organelle) associated protein 4	17	-594410	AF258545	50628	17p13	Hs.499620	24	spliceosomal snRNP biogenesis protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm cytosol rRNA processing mRNA processing RNA splicing Cajal body small nuclear ribonucleoprotein complex
225278_at	-0.301	9.694	-2.203	4.344e-02	0.372	-3.990	PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	1	-145093308	BF593382	5565	1q21.1	Hs.50732	21	protein binding nucleoplasm cytosol cAMP-dependent protein kinase complex fatty acid biosynthetic process signal transduction protein kinase binding AMP-activated protein kinase complex regulation of fatty acid oxidation	Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
235066_at	-0.365	4.334	-2.203	4.344e-02	0.372	-3.990	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AI078534	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
200051_at	-0.221	6.779	-2.203	4.345e-02	0.372	-3.991	SART1	squamous cell carcinoma antigen recognized by T cells	11	65485735	NM_005146	9092	11q13.1	Hs.502883	27	molecular_function nucleus spliceosomal complex cytoplasm cytosol mRNA processing cell cycle arrest RNA splicing induction of apoptosis by intracellular signals positive regulation of cytotoxic T cell differentiation
234511_at	0.242	4.597	2.202	4.346e-02	0.372	-3.991	ANKRD60	ankyrin repeat domain 60	20		AL354776	140731	20q13.32		1
1558641_at	0.335	8.374	2.202	4.346e-02	0.372	-3.991	LOC202051	hypothetical protein LOC202051	5	-138760356	AK098740	202051	5q31.2	Hs.373612	3	cytoplasm multicellular organismal development spermatogenesis cell differentiation
1554660_a_at	-0.480	3.918	-2.202	4.350e-02	0.372	-3.992	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	BC036200	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
216865_at	0.291	3.859	2.202	4.350e-02	0.372	-3.992	COL14A1	collagen, type XIV, alpha 1	8	121206532	M64108	7373	8q23	Hs.409662	20	extracellular matrix structural constituent collagen binding extracellular region collagen collagen type XIV cell-cell adhesion collagen fibril organization protein binding, bridging
217892_s_at	-0.547	7.362	-2.202	4.353e-02	0.372	-3.992	LIMA1	LIM domain and actin binding 1	12	-48855829, -48855829	NM_016357	51474	12q13	Hs.525419	23	stress fiber actin monomer binding cytoplasm focal adhesion zinc ion binding actin cytoskeleton cell junction negative regulation of actin filament depolymerization ruffle organization metal ion binding actin filament binding actin filament bundle formation
224265_s_at	0.327	4.436	2.201	4.354e-02	0.372	-3.992	ZAN	zonadhesin	7	100169184	AF332980	7455	7q22	Hs.307004	5	protein binding plasma membrane binding of sperm to zona pellucida integral to membrane cell-cell adhesion
241619_at	-0.453	5.260	-2.201	4.355e-02	0.372	-3.993	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	BF526558	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
218238_at	-0.471	6.646	-2.201	4.356e-02	0.372	-3.993	GTPBP4	GTP binding protein 4	10	1024348	NM_012341	23560	10p15-p14	Hs.215766	10	regulation of cyclin-dependent protein kinase activity nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization
203146_s_at	0.290	6.491	2.201	4.359e-02	0.372	-3.993	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	6	-29677983, -29677983, -1025320, -1025320, -827282, -827282	NM_001470	2550	6p21.31	Hs.167017	66	receptor activity G-protein coupled receptor activity GABA-B receptor activity protein binding extracellular region plasma membrane integral to plasma membrane signal transduction negative regulation of adenylate cyclase activity gamma-aminobutyric acid signaling pathway cell junction synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
226426_at	-0.328	6.203	-2.201	4.360e-02	0.372	-3.994	ADNP	activity-dependent neuroprotector homeobox	20	-48940289	BG149849	23394	20q13.13	Hs.570355	10	chromatin binding transcription factor activity dolichyl-phosphate beta-D-mannosyltransferase activity protein binding extracellular space intracellular nucleus nucleolus regulation of transcription, DNA-dependent GPI anchor biosynthetic process zinc ion binding dolichol metabolic process negative regulation of neuron apoptosis sequence-specific DNA binding metal ion binding
224997_x_at	-0.782	9.509	-2.201	4.361e-02	0.372	-3.994	H19	H19, imprinted maternally expressed transcript (non-protein coding)	11	-1972981	AL575306	283120	11p15.5	Hs.533566	41
227291_s_at	0.461	10.617	2.200	4.366e-02	0.373	-3.995	BOLA3	bolA homolog 3 (E. coli)	2	-74216035	AI380704	388962	2p13.1	Hs.61472	4	molecular_function cellular_component biological_process
235779_at	0.231	3.073	2.200	4.367e-02	0.373	-3.995	LOC284408	hypothetical protein LOC284408	19		AW467077	284408	19q13.13	Hs.570010	1
207770_x_at	0.343	5.873	2.200	4.369e-02	0.373	-3.995	CSH2	chorionic somatomammotropin hormone 2	17	-59303104, -59303103	NM_022644	1443	17q24.2	Hs.654390 Hs.654515	21
230435_at	0.391	6.759	2.200	4.370e-02	0.373	-3.996	LOC375190	hypothetical protein LOC375190	2	24199853	BF108666	375190	2p23.3	Hs.710370	4
244431_at	0.318	4.779	2.199	4.371e-02	0.373	-3.996	KILLIN	killin protein	10	-89608897	AA057423	100144748	10q23	Hs.559820	2	DNA binding nucleus apoptosis cell cycle
223267_at	-0.297	7.695	-2.199	4.372e-02	0.373	-3.996	RG9MTD1	RNA (guanine-9-) methyltransferase domain containing 1	3	102763401	AF226052	54931	3q12.3	Hs.643184 Hs.715724	3	protein binding mitochondrion tRNA processing methyltransferase activity transferase activity
208159_x_at	0.488	6.452	2.199	4.372e-02	0.373	-3.996	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	12	31118045	NM_004399	1663	12p11	Hs.443960	13	mitotic sister chromatid segregation S phase of mitotic cell cycle G2/M transition of mitotic cell cycle nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP binding nucleus nucleolus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle positive regulation of cell proliferation hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
238952_x_at	0.224	3.760	2.199	4.372e-02	0.373	-3.996	ZNF829	zinc finger protein 829	19	-42074092	BF439163	374899	19q13.12	Hs.124047	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552853_at	0.330	3.869	2.199	4.374e-02	0.373	-3.996	VWA5B1	von Willebrand factor A domain containing 5B1	1	20489998	NM_144623	127731	1p36.12	Hs.205178	3	extracellular region
48531_at	-0.387	7.471	-2.199	4.374e-02	0.373	-3.996	TNIP2	TNFAIP3 interacting protein 2	4	-2713184, -2713184	AA522816	79155	4p16.3	Hs.719161	20	protein binding cytoplasm I-kappaB kinase/NF-kappaB cascade
228323_at	-0.444	3.685	-2.199	4.375e-02	0.373	-3.996	CASC5	cancer susceptibility candidate 5	15	38673738	BF248364	57082	15q14	Hs.181855	16	acrosomal vesicle acrosome assembly protein binding nucleus
239660_at	-0.608	7.151	-2.199	4.376e-02	0.373	-3.997	C20orf74	chromosome 20 open reading frame 74	20	-20321410	BF110518	57186	20p11.22	Hs.472285	4	GTPase activator activity intracellular cytoplasm regulation of small GTPase mediated signal transduction
217550_at	-0.379	5.599	-2.199	4.378e-02	0.373	-3.997	ATF6	activating transcription factor 6	1	160002707	AA576497	22926	1q22-q23	Hs.492740	43	transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity nucleus nuclear envelope nucleoplasm endoplasmic reticulum endoplasmic reticulum membrane regulation of transcription from RNA polymerase II promoter protein folding response to unfolded protein positive regulation of gene-specific transcription involved in unfolded protein response signal transduction membrane integral to membrane sequence-specific DNA binding protein dimerization activity	Alzheimer's disease
230398_at	0.247	4.824	2.199	4.378e-02	0.373	-3.997	TNS4	tensin 4	17	-35885605	AA158731	84951	17q21.2	Hs.438292	17	actin binding protein binding cytoplasm cytoskeleton focal adhesion apoptosis protein localization cell junction
203278_s_at	-0.390	6.444	-2.198	4.379e-02	0.373	-3.997	PHF21A	PHD finger protein 21A	11	-45907445	NM_016621	51317	11p11.2	Hs.502458	11	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding nucleus zinc ion binding chromatin modification regulation of transcription metal ion binding
214751_at	0.547	4.058	2.198	4.382e-02	0.373	-3.998	ZNF468	zinc finger protein 468	19	-58033596	BE541042	90333	19q13.41	Hs.467223	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200877_at	-0.347	9.752	-2.198	4.384e-02	0.373	-3.998	CCT4	chaperonin containing TCP1, subunit 4 (delta)	2	-61948765	NM_006430	10575	2p15	Hs.421509	18	nucleotide binding ATP binding cytoplasm chaperonin-containing T-complex protein folding melanosome unfolded protein binding
200596_s_at	-0.270	8.292	-2.198	4.386e-02	0.373	-3.999	EIF3A	eukaryotic translation initiation factor 3, subunit A	10	-120784530	BE614908	8661	10q26	Hs.523299	38	formation of translation initiation complex translation initiation factor activity translation initiation factor activity structural molecule activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex
220331_at	0.315	5.817	2.197	4.390e-02	0.373	-3.999	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1	14	99220507	NM_006668	10858	14q32.1	Hs.25121	40	endoplasmic reticulum microsome lipid metabolic process cholesterol catabolic process nervous system development steroid metabolic process steroid hydroxylase activity electron carrier activity membrane integral to membrane heme binding cholesterol 24-hydroxylase activity metal ion binding oxidation reduction	Primary bile acid biosynthesis
236034_at	0.369	4.602	2.197	4.391e-02	0.373	-4.000	ANGPT2	angiopoietin 2	8	-6344580	AA083514	285	8p23.1	Hs.583870	137	angiogenesis receptor binding extracellular region extracellular space signal transduction multicellular organismal development cell differentiation
213210_at	0.333	5.277	2.197	4.394e-02	0.373	-4.000	TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	11	62295450	AI005317	10629	11q12.3	Hs.714400	13	histone deacetylase complex DNA binding RNA polymerase II transcription factor activity transcription coactivator activity histone acetyltransferase activity protein binding nucleus chromatin remodeling transcription initiation regulation of transcription from RNA polymerase II promoter transcription initiation factor activity STAGA complex histone H3 acetylation regulation of transcription factor activity	Basal transcription factors
200731_s_at	-0.497	9.773	-2.197	4.395e-02	0.373	-4.001	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	AW165960	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
201671_x_at	-0.349	8.346	-2.196	4.397e-02	0.373	-4.001	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	18	148482	BC003556	9097	18p11.32	Hs.464416 Hs.707058	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity
218087_s_at	-0.601	10.392	-2.196	4.402e-02	0.374	-4.002	SORBS1	sorbin and SH3 domain containing 1	10	-97061519, -97061519	NM_015385	10580	10q23.3-q24.1	Hs.719081	35	stress fiber actin binding SH3/SH2 adaptor activity SH3/SH2 adaptor activity insulin receptor binding nucleus cytoplasm cytosol cytoskeleton plasma membrane insulin receptor complex zonula adherens cell-substrate adherens junction transport insulin receptor signaling pathway glucose transport cell junction stress fiber formation membrane raft positive regulation of glycogen biosynthetic process positive regulation of glucose import positive regulation of lipid biosynthetic process focal adhesion formation	PPAR signaling pathway Adherens junction Insulin signaling pathway
219455_at	-0.280	5.015	-2.195	4.406e-02	0.374	-4.003	C7orf63	chromosome 7 open reading frame 63	7	89712423	NM_024788	79846	7q21.13	Hs.657403	4	binding
208342_x_at	0.368	3.460	2.195	4.406e-02	0.374	-4.003	CSH2	chorionic somatomammotropin hormone 2	17	-59303104, -59303103	NM_022645	1443	17q24.2	Hs.654390 Hs.654515	21
232395_x_at	-0.275	2.682	-2.195	4.411e-02	0.374	-4.004	AGBL3	ATP/GTP binding protein-like 3	7	134321798	AI674787	340351	7q33	Hs.648616	4	metallocarboxypeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
213799_s_at	0.290	4.622	2.195	4.411e-02	0.374	-4.004	PTPRA	protein tyrosine phosphatase, receptor type, A	20	2792840, 2802141, 2851852	BF740139	5786	20p13	Hs.269577	58	transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid phosphorylation protein amino acid dephosphorylation membrane hydrolase activity
234018_s_at	-0.873	4.316	-2.195	4.412e-02	0.374	-4.004	SEL1L2	sel-1 suppressor of lin-12-like 2 (C. elegans)	20	-13778049	AL137678	80343	20p12.1	Hs.590879	1	binding membrane integral to membrane
212609_s_at	-0.214	6.247	-2.194	4.417e-02	0.374	-4.005	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	1	-241733106, -241718157	U79271	10000	1q43-q44	Hs.498292	45	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation signal transduction membrane transferase activity	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Tight junction Toll-like receptor signaling pathway Jak-STAT signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
206288_at	-0.493	5.125	-2.194	4.420e-02	0.375	-4.006	PGGT1B	protein geranylgeranyltransferase type I, beta subunit	5	-114574425	NM_005023	5229	5q22.3	Hs.254006	8	prenyltransferase activity CAAX-protein geranylgeranyltransferase activity CAAX-protein geranylgeranyltransferase complex zinc ion binding transferase activity protein amino acid geranylgeranylation metal ion binding
200066_at	-0.351	8.580	-2.193	4.421e-02	0.375	-4.006	IK	IK cytokine, down-regulator of HLA II	5	140007567	AF182645	3550	2p15-p14 5q31.3	Hs.421245	13	extracellular space soluble fraction nucleus immune response cell-cell signaling
1553849_at	-0.314	3.378	-2.193	4.422e-02	0.375	-4.006	CCDC26	coiled-coil domain containing 26	8		NM_145050	137196	8q24.21	Hs.679457	5
207887_s_at	0.250	4.727	2.193	4.424e-02	0.375	-4.006	CALCR	calcitonin receptor	7	-92891734	AB022177	799	7q21.3	Hs.489127	61	acrosomal vesicle calcitonin receptor activity plasma membrane integral to plasma membrane G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway elevation of cytosolic calcium ion concentration negative regulation of ossification osteoclast differentiation calcitonin binding calcitonin binding regulation of mRNA stability microtubule-based flagellum part positive regulation of adenylate cyclase activity response to glucocorticoid stimulus	Neuroactive ligand-receptor interaction
205568_at	0.345	4.611	2.193	4.425e-02	0.375	-4.006	AQP9	aquaporin 9	15	56217699	NM_020980	366	15q22.1-q22.2	Hs.104624	18	transporter activity amine transmembrane transporter activity purine transmembrane transporter activity purine transmembrane transporter activity pyrimidine transmembrane transporter activity pyrimidine transmembrane transporter activity integral to plasma membrane water transport water transport purine transport purine transport immune response response to osmotic stress excretion metabolic process response to organic substance response to organic substance polyol transmembrane transporter activity water channel activity water channel activity porin activity polyol transport polyol transport amine transport amine transport pyrimidine transport pyrimidine transport membrane water homeostasis response to mercury ion response to mercury ion carboxylic acid transport carboxylic acid transmembrane transporter activity
1556051_a_at	-0.443	4.579	-2.193	4.426e-02	0.375	-4.007	BICD1	bicaudal D homolog 1 (Drosophila)	12	32151451	CA777994	636	12p11.2-p11.1	Hs.505202	17	structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis
1553873_at	-0.828	7.926	-2.193	4.426e-02	0.375	-4.007	KLHL34	kelch-like 34 (Drosophila)	X	-21583529	NM_153270	257240	Xp22.12	Hs.448572	4	protein binding
233543_s_at	-0.633	5.276	-2.193	4.428e-02	0.375	-4.007	FAM175A	family with sequence similarity 175, member A	4	-84601119	AK021582	84142	4q21.21-q21.23	Hs.334772	15	protein binding nucleus double-strand break repair response to DNA damage stimulus response to ionizing radiation chromatin modification G2/M transition DNA damage checkpoint polyubiquitin binding positive regulation of DNA repair BRCA1-A complex
228093_at	0.258	5.602	2.192	4.430e-02	0.375	-4.007	ZNF599	zinc finger protein 599	19	-39940818	AW300140	148103	19q13.11	Hs.590961	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200669_s_at	-0.357	10.055	-2.192	4.431e-02	0.375	-4.008	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	4	-103936216, -103936216, -103936216, -103936216, -103936216, -103936216	NM_003340	7323	4q24	Hs.518773	28	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity BMP signaling pathway regulation of protein metabolic process	Ubiquitin mediated proteolysis
1557388_at	0.286	4.754	2.191	4.438e-02	0.375	-4.009	RTTN	rotatin	18	-65822020	BC013774	25914	18q22.2	Hs.654809	3	binding multicellular organismal development determination of left/right symmetry
225292_at	0.413	5.916	2.191	4.439e-02	0.375	-4.009	COL27A1	collagen, type XXVII, alpha 1	9	115958051	AU145229	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
202631_s_at	-0.361	5.006	-2.191	4.439e-02	0.375	-4.009	APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	17	-55875301	NM_006380	10513	17q21-q23	Hs.84084	10	microtubule motor activity protein binding nucleus cytoplasm cytoskeleton microtubule microtubule associated complex intracellular protein transport membrane
200870_at	-0.343	10.211	-2.191	4.439e-02	0.375	-4.009	STRAP	serine/threonine kinase receptor associated protein	12	15926554	NM_007178	11171	12p12.3	Hs.719087	23	nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing identical protein binding
230745_s_at	0.331	5.237	2.191	4.440e-02	0.375	-4.009	TOX3	TOX high mobility group box family member 3	16	-51029418, -51029418	AI347147	27324	16q12.1	Hs.460789	11	DNA binding nucleus
215584_at	0.287	6.311	2.191	4.441e-02	0.375	-4.010	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	7	43118722	AK022679	23072	7p14.1-p13	Hs.164453	8	protein binding intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process
226082_s_at	-0.367	6.250	-2.191	4.441e-02	0.375	-4.010	SFRS15	splicing factor, arginine/serine-rich 15	21	-31965183	AW513629	57466	21q22.1	Hs.17255	12	nucleotide binding RNA binding nucleus nucleolus mRNA processing protein C-terminus binding
211612_s_at	-0.434	5.886	-2.190	4.447e-02	0.375	-4.011	IL13RA1	interleukin 13 receptor, alpha 1	X	117745586	U62858	3597	Xq24	Hs.496646	25	receptor activity cytokine receptor activity protein binding plasma membrane interleukin-13 receptor complex cell surface receptor linked signal transduction integral to membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
237722_at	0.281	3.499	2.190	4.450e-02	0.375	-4.011	FLI1	Friend leukemia virus integration 1	11	128069022	AW444915	2313	11q24.1-q24.3	Hs.504281	53	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent hemostasis organ morphogenesis sequence-specific DNA binding
229696_at	-0.291	6.154	-2.190	4.451e-02	0.375	-4.011	FECH	ferrochelatase (protoporphyria)	18	-53363070	AI807483	2235	18q21.3	Hs.365365	61	ferrochelatase activity ferrochelatase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix generation of precursor metabolites and energy heme biosynthetic process ferrous iron binding response to light stimulus detection of UV membrane protoporphyrinogen IX metabolic process metal ion binding 2 iron, 2 sulfur cluster binding	Porphyrin and chlorophyll metabolism Metabolic pathways
1555007_s_at	0.288	4.426	2.190	4.452e-02	0.375	-4.012	WDR66	WD repeat domain 66	12	120840862	BC036233	144406	12q24.31	Hs.709837	4
208897_s_at	-0.367	7.006	-2.190	4.452e-02	0.375	-4.012	DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	2	118288724	BC003360	8886	2q14.1	Hs.363492	6	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding hydrolase activity
203824_at	-1.729	8.236	-2.190	4.453e-02	0.375	-4.012	TSPAN8	tetraspanin 8	12	-69805143	NM_004616	7103	12q14.1-q21.1	Hs.170563	23	signal transducer activity lysosome protein amino acid glycosylation membrane integral to membrane
236703_at	-0.662	6.651	-2.190	4.455e-02	0.376	-4.012	NT5C2	5'-nucleotidase, cytosolic II	10	-104835929	BF114733	22978	10q24.32-q24.33	Hs.97439	12	nucleotide binding magnesium ion binding protein binding cytoplasm cytosol 5'-nucleotidase activity 5'-nucleotidase activity nucleotide metabolic process hydrolase activity	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
213323_s_at	0.236	7.015	2.189	4.458e-02	0.376	-4.013	ZC3H7B	zinc finger CCCH-type containing 7B	22	40027512	BE855831	23264	22q13.2	Hs.592188	12	nucleic acid binding protein binding intracellular nucleus zinc ion binding interspecies interaction between organisms metal ion binding
232532_at	0.337	4.885	2.189	4.459e-02	0.376	-4.013	QRICH2	glutamine rich 2	17	-71781724	AL136774	84074	17q25.1	Hs.252739	2	protein binding
222705_s_at	0.340	3.865	2.189	4.460e-02	0.376	-4.013	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	13	40261546	BC002702	10166	13q14	Hs.646645 Hs.655240	17	urea cycle L-ornithine transmembrane transporter activity mitochondrial ornithine transport transporter activity binding mitochondrion mitochondrial inner membrane cellular amino acid metabolic process transport membrane integral to membrane
210300_at	0.228	6.099	2.188	4.464e-02	0.376	-4.014	REM1	RAS (RAD and GEM)-like GTP-binding 1	20	29526765	AF152863	28954	20q11.21	Hs.247729	8	nucleotide binding calmodulin binding GTP binding small GTPase mediated signal transduction
232515_at	0.226	6.190	2.188	4.464e-02	0.376	-4.014	ASB3	ankyrin repeat and SOCS box-containing 3	2	-53750621	AU144567	51130	2p16-p14	Hs.40763	10	intracellular signaling cascade modification-dependent protein catabolic process
213220_at	-0.295	6.909	-2.188	4.466e-02	0.376	-4.015	NCRNA00081	non-protein coding RNA 81	10	-112648478, -112648478	AV706096	92482	10q25.2	Hs.232543 Hs.651480	4	cytoplasm cilium
239135_at	-0.600	4.822	-2.188	4.467e-02	0.376	-4.015	CPPED1	calcineurin-like phosphoesterase domain containing 1	16	-12661156	AI675054	55313	16p13.12	Hs.460002	4	hydrolase activity metal ion binding
223532_at	0.315	5.944	2.188	4.468e-02	0.376	-4.015	ANKRD39	ankyrin repeat domain 39	2	-96877450	AF151034	51239	2q11.2	Hs.709507	6
232188_at	0.254	2.860	2.188	4.468e-02	0.376	-4.015	AKAP13	A kinase (PRKA) anchor protein 13	15	83724874, 84021271	AL133427	11214	15q24-q25	Hs.459211 Hs.710656	38	cAMP-dependent protein kinase activity signal transducer activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular membrane fraction nucleus cytoplasm intracellular signaling cascade biological_process zinc ion binding membrane diacylglycerol binding regulation of Rho protein signal transduction metal ion binding
213227_at	-0.353	7.810	-2.188	4.470e-02	0.376	-4.015	PGRMC2	progesterone receptor membrane component 2	4	-129410746	BE879873	10424	4q26	Hs.507910	9	steroid hormone receptor activity receptor activity steroid binding protein binding membrane integral to membrane heme binding
219862_s_at	-0.431	7.863	-2.188	4.471e-02	0.376	-4.016	NARF	nuclear prelamin A recognition factor	17	78009348, 78009828	NM_012336	26502	17q25.3	Hs.256526 Hs.600304	10	lamin binding nucleus lamin filament nuclear lumen
219596_at	0.429	6.128	2.188	4.472e-02	0.376	-4.016	THAP10	THAP domain containing 10	15	-68960734	NM_020147	56906	15q23	Hs.591123	5	DNA binding zinc ion binding metal ion binding
224580_at	0.303	4.144	2.187	4.472e-02	0.376	-4.016	SLC38A1	solute carrier family 38, member 1	12	-44863107	BF515894	81539	12q13.11	Hs.694701	11	sodium:amino acid symporter activity membrane fraction plasma membrane ion transport sodium ion transport glutamine transport L-glutamine transmembrane transporter activity symporter activity integral to membrane axon sodium ion binding
225534_at	0.360	9.724	2.187	4.473e-02	0.376	-4.016	C8orf40	chromosome 8 open reading frame 40	8	42515454, 42515874, 42515921, 42516095	AV711345	114926	8p11.21	Hs.655320	4	membrane integral to membrane
214440_at	0.295	4.199	2.187	4.474e-02	0.376	-4.016	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)	8	18072250, 18111897, 18123456	NM_000662	9	8p23.1-p21.3	Hs.591847	163	arylamine N-acetyltransferase activity cytoplasm cytosol metabolic process acetyltransferase activity transferase activity	Caffeine metabolism Drug metabolism - other enzymes Metabolic pathways
218268_at	-0.333	6.976	-2.187	4.478e-02	0.376	-4.017	TBC1D15	TBC1 domain family, member 15	12	70519753	NM_022771	64786	12q21.1	Hs.284630 Hs.595154	12	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
230151_at	-0.341	6.767	-2.186	4.481e-02	0.376	-4.017	C13orf1	chromosome 13 open reading frame 1	13	-49384842	AW009330	57213	13q14	Hs.44235	11
210956_at	0.251	4.022	2.186	4.481e-02	0.376	-4.017	PPYR1	pancreatic polypeptide receptor 1	10	46503539	U42387	5540	10q11.2	Hs.524719	14	peptide YY receptor activity pancreatic polypeptide receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway digestion feeding behavior blood circulation	Neuroactive ligand-receptor interaction
1557124_at	0.226	5.287	2.186	4.481e-02	0.376	-4.017	LOC440104	hypothetical LOC440104	12		AK091705	440104	12q13.2	Hs.616500	3
210335_at	-0.318	2.782	-2.186	4.481e-02	0.376	-4.017	RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	12	-84722461	AF056209	9182	12q21.31	Hs.527881	4	transporter activity protein binding endosome cytosol protein targeting signal transduction trans-Golgi network transport vesicle membrane endosome transport
219541_at	0.235	5.901	2.186	4.482e-02	0.376	-4.018	LIME1	Lck interacting transmembrane adaptor 1	20	61838421	NM_017806	54923	20q13.3	Hs.233220	10	plasma membrane immune response integral to membrane
243679_at	0.311	5.120	2.186	4.482e-02	0.376	-4.018	JPH3	junctophilin 3	16	86193999	AI680727	57338	16q24.3	Hs.592068	18	molecular_function protein binding endoplasmic reticulum plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
204209_at	-0.458	6.227	-2.186	4.483e-02	0.376	-4.018	PCYT1A	phosphate cytidylyltransferase 1, choline, alpha	3	-197449649	AI638771	5130	3q29	Hs.435767	15	choline-phosphate cytidylyltransferase activity soluble fraction cytoplasm endoplasmic reticulum membrane cytosol phosphatidylcholine biosynthetic process phospholipid biosynthetic process biosynthetic process response to abiotic stimulus membrane transferase activity nucleotidyltransferase activity glycogen granule	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
201503_at	-0.450	9.351	-2.186	4.484e-02	0.376	-4.018	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	BG500067	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
206828_at	0.222	2.635	2.186	4.489e-02	0.377	-4.019	TXK	TXK tyrosine kinase	4	-47763166	NM_003328	7294	4p12	Hs.479669	16	nucleotide binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity	Leukocyte transendothelial migration
213004_at	-0.440	6.725	-2.185	4.490e-02	0.377	-4.019	ANGPTL2	angiopoietin-like 2	9	-128889448	AI074333	23452	9q34	Hs.653262	11	receptor binding extracellular region extracellular space signal transduction multicellular organismal development
233353_at	0.267	4.397	2.185	4.490e-02	0.377	-4.019	FER1L5	fer-1-like 5 (C. elegans)	2	96672300, 96724920	AL133022	90342	2q11.2	Hs.534025	2	membrane integral to membrane
203335_at	0.335	11.593	2.185	4.491e-02	0.377	-4.019	PHYH	phytanoyl-CoA 2-hydroxylase	10	-13359801, -13359801	NM_006214	5264	10p13	Hs.498732	28	iron ion binding protein binding peroxisome lipid metabolic process nervous system development visual perception electron carrier activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding metal ion binding phytanoyl-CoA dioxygenase activity response to stimulus oxidation reduction
1559635_at	0.249	4.594	2.185	4.494e-02	0.377	-4.020	CASC4	cancer susceptibility candidate 4	15	42368220	AK098265	113201	15q15.3	Hs.512867	6	membrane integral to membrane
223574_x_at	0.325	4.099	2.185	4.495e-02	0.377	-4.020	PPP2R2C	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	4	-6373205, -6373205	AF086924	5522	4p16.1	Hs.479069	24	protein phosphatase type 2A complex signal transduction protein phosphatase type 2A regulator activity	Tight junction
202726_at	0.273	5.395	2.185	4.496e-02	0.377	-4.020	LIG1	ligase I, DNA, ATP-dependent	19	-53310514	NM_000234	3978	19q13.2-q13.3	Hs.1770	54	nucleotide binding magnesium ion binding DNA binding DNA ligase (ATP) activity ATP binding nucleus nucleoplasm DNA replication DNA repair nucleotide-excision repair, DNA gap filling DNA recombination response to DNA damage stimulus cell cycle anatomical structure morphogenesis ligase activity V(D)J recombination cell division	DNA replication Base excision repair Nucleotide excision repair Mismatch repair
235520_at	-0.381	3.502	-2.185	4.497e-02	0.377	-4.020	ZNF280C	zinc finger protein 280C	X	-129164362	AA805654	55609	Xq26.1	Hs.308418	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
210019_at	0.265	4.785	2.184	4.498e-02	0.377	-4.021	CALML3	calmodulin-like 3	10	5556923	M36707	810	10pter-p13	Hs.239600	16	calcium ion binding	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
236551_at	0.278	2.875	2.184	4.498e-02	0.377	-4.021	ZNF311	zinc finger protein 311	6	-29070572, -417899, -219937	BF508689	282890	6p22.1	Hs.148218	4	DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211866_x_at	0.268	5.244	2.184	4.500e-02	0.377	-4.021	HFE	hemochromatosis	6	26195487	AF079409	3077	6p21.3	Hs.233325	592	antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome
208066_s_at	-0.408	6.996	-2.184	4.504e-02	0.377	-4.022	GTF2B	general transcription factor IIB	1	-89090908	NM_001514	2959	1p22-p21	Hs.481852	98	translation initiation factor activity protein binding nucleus nucleoplasm transcription factor complex regulation of transcription, DNA-dependent transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter translational initiation zinc ion binding general RNA polymerase II transcription factor activity transcription regulator activity interspecies interaction between organisms metal ion binding	Basal transcription factors
226336_at	-0.418	6.204	-2.184	4.504e-02	0.377	-4.022	PPIA	peptidylprolyl isomerase A (cyclophilin A)	7	44802765	T62044	5478	7p13	Hs.356331 Hs.598115	164	peptidyl-prolyl cis-trans isomerase activity extracellular region nucleus cytoplasm cytosol cytosol protein folding isomerase activity provirus integration initiation of viral infection peptide binding interspecies interaction between organisms regulation of viral genome replication regulation of viral genome replication virion binding unfolded protein binding
202092_s_at	-0.486	7.279	-2.183	4.508e-02	0.378	-4.023	ARL2BP	ADP-ribosylation factor-like 2 binding protein	16	55836538	BF244411	23568	16q13	Hs.632873 Hs.645184	6	small GTPase regulator activity cytoplasm mitochondrion mitochondrial intermembrane space centrosome signal transduction
228588_s_at	-0.485	9.960	-2.183	4.509e-02	0.378	-4.023	UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	5	133734768	AI499236	7320	5q23-q31	Hs.615284 Hs.644421	23	nucleotide binding protein polyubiquitination chromatin ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus replication fork cytoplasm plasma membrane postreplication repair postreplication repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein monoubiquitination response to DNA damage stimulus spermatogenesis sperm axoneme assembly response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination response to drug protein stabilization regulation of protein metabolic process protein autoubiquitination Wnt receptor signaling pathway through beta-catenin	Ubiquitin mediated proteolysis
209252_at	-0.295	7.765	-2.183	4.513e-02	0.378	-4.024	HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)	5	140051201	U18937	23438	5q31.3	Hs.432560	8	nucleotide binding histidine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix histidyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
208414_s_at	0.275	6.132	2.183	4.514e-02	0.378	-4.024	HOXB3	homeobox B3	17	-43981230	NM_002146	3213	17q21.3	Hs.654560	21	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding embryonic skeletal system morphogenesis cartilage development definitive hemopoiesis
213660_s_at	0.223	4.978	2.182	4.515e-02	0.378	-4.024	TOP3B	topoisomerase (DNA) III beta	22	-20641402	AA581879	8940	22q11.22	Hs.436401	15	nucleotide binding condensed chromosome DNA topoisomerase type I activity protein binding ATP binding nucleus DNA topological change DNA unwinding during replication chromosome segregation	Homologous recombination
202747_s_at	0.380	8.325	2.182	4.517e-02	0.378	-4.024	ITM2A	integral membrane protein 2A	X	-78502536	NM_004867	9452	Xq13.3-Xq21.2	Hs.17109 Hs.694944	14	cytoplasm plasma membrane integral to membrane
215690_x_at	-0.284	8.023	-2.182	4.518e-02	0.378	-4.025	GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	8	145209511	AL157437	8733	8q24.3	Hs.627962	16	GPI-anchor transamidase activity protein binding endoplasmic reticulum protein complex assembly protein retention in ER lumen tubulin binding membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein attachment of GPI anchor to protein GPI anchor binding GPI-anchor transamidase complex	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
231182_at	0.230	3.258	2.182	4.518e-02	0.378	-4.025	WIPF1	WAS/WASL interacting protein family, member 1	2	-175132547, -175132547	BF446719	7456	2q31.1	Hs.128067	29	actin binding profilin binding nucleus nucleolus cytoplasm protein complex assembly actin polymerization or depolymerization actin cytoskeleton cytoplasmic vesicle
210533_at	0.317	2.627	2.182	4.519e-02	0.378	-4.025	MSH4	mutS homolog 4 (E. coli)	1	76035217	AF104243	4438	1p31	Hs.216639	20	nucleotide binding synaptonemal complex ovarian follicle development DNA binding ATP binding nucleus mismatch repair meiosis synapsis reciprocal meiotic recombination spermatogenesis female gamete generation mismatched DNA binding
219286_s_at	-0.425	7.781	-2.182	4.519e-02	0.378	-4.025	RBM15	RNA binding motif protein 15	1	110683467	NM_022768	64783	1p13	Hs.435947 Hs.708172	13	nucleotide binding RNA binding protein binding nucleus negative regulation of transcription interspecies interaction between organisms
232467_at	0.408	5.381	2.182	4.519e-02	0.378	-4.025	KIRREL	kin of IRRE like (Drosophila)	1	156229686	BE301156	55243	1q21-q25	Hs.609291 Hs.657006	15	plasma membrane integral to membrane
218371_s_at	-0.343	6.257	-2.182	4.520e-02	0.378	-4.025	PSPC1	paraspeckle component 1	13	-19175008, -19146895	NM_018282	55269	13q12.11	Hs.213198	9	nucleotide binding RNA binding protein binding nucleus nucleolus cytoplasm nuclear matrix regulation of transcription
218451_at	0.232	4.382	2.182	4.520e-02	0.378	-4.025	CDCP1	CUB domain containing protein 1	3	-45126734, -45098772	NM_022842	64866	3p21.31	Hs.476093	21	extracellular region plasma membrane integral to membrane
232367_x_at	0.262	6.715	2.182	4.520e-02	0.378	-4.025	ZNF598	zinc finger protein 598	16	-1987768	BG341703	90850	16p13.3	Hs.343828	5	protein binding intracellular zinc ion binding metal ion binding
209658_at	-0.261	8.444	-2.182	4.522e-02	0.378	-4.025	CDC16	cell division cycle 16 homolog (S. cerevisiae)	13	114018463	AF164598	8881	13q34	Hs.374127	32	binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
224666_at	0.267	7.798	2.182	4.523e-02	0.378	-4.025	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	16	-27143815	AF161451	197370	16p12.1	Hs.284295	6	nucleus DNA repair DNA recombination response to DNA damage stimulus zinc ion binding metal ion binding
235576_at	0.266	4.653	2.182	4.523e-02	0.378	-4.025	WDR27	WD repeat domain 27	6	-169599231	AW474542	253769	6q27	Hs.709476	2
227962_at	-0.333	7.234	-2.181	4.524e-02	0.378	-4.026	ACOX1	acyl-Coenzyme A oxidase 1, palmitoyl	17	-71449186	BF435852	51	17q24-q25 17q25.1	Hs.464137	26	acyl-CoA dehydrogenase activity acyl-CoA oxidase activity acyl-CoA oxidase activity cytoplasm mitochondrion peroxisome peroxisomal membrane generation of precursor metabolites and energy lipid metabolic process fatty acid beta-oxidation prostaglandin metabolic process spermatogenesis electron carrier activity protein N-terminus binding FAD binding oxidation reduction	Fatty acid metabolism alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
231705_at	0.196	5.203	2.181	4.524e-02	0.378	-4.026	HRSP12	heat-responsive protein 12	8	-99183742	AV654263	10247	8q22	Hs.18426	12	endonuclease activity nucleus cytoplasm regulation of translational termination hydrolase activity
35254_at	-0.216	5.737	-2.181	4.524e-02	0.378	-4.026	TRAFD1	TRAF-type zinc finger domain containing 1	12	111047731	AB007447	10906	12q	Hs.5148	10	protein binding intracellular zinc ion binding metal ion binding
222495_at	-0.367	7.620	-2.181	4.531e-02	0.378	-4.027	TMEM167B	transmembrane protein 167B	1	109434925, 126731	AV712912	56900	1p13.3	Hs.82933	4	membrane integral to membrane
1553983_at	0.224	5.773	2.180	4.535e-02	0.378	-4.028	DTYMK	deoxythymidylate kinase (thymidylate kinase)	2	-242263829, -92952	AF258562	1841	2q37.3	Hs.471873	12	nucleotide binding thymidylate kinase activity ATP binding cytosol dTDP biosynthetic process cell cycle cell proliferation nucleotide biosynthetic process kinase activity transferase activity nucleoside kinase activity	Pyrimidine metabolism Metabolic pathways
1557682_a_at	0.241	5.313	2.180	4.535e-02	0.378	-4.028	RP11-297H3.4	hypothetical LOC284688	1	-168507169	BG150294	284688	1q24.2	Hs.135668	2
225120_at	-0.345	7.366	-2.180	4.537e-02	0.378	-4.028	PURB	purine-rich element binding protein B	7	-44882416	N25931	5814	7p13	Hs.349150 Hs.596321	13	translation repressor activity, nucleic acid binding double-stranded DNA binding single-stranded DNA binding transcription factor activity mRNA binding nucleus DNA replication factor A complex transcription factor binding specific transcriptional repressor activity purine-rich negative regulatory element binding regulation of transcription regulation of myeloid cell differentiation negative regulation of transcription, DNA-dependent SMAD binding
209201_x_at	0.364	4.486	2.180	4.537e-02	0.378	-4.028	CXCR4	chemokine (C-X-C motif) receptor 4	2	-136588388, -136588388	L01639	7852	2q21	Hs.593413	604	activation of MAPK activity response to hypoxia actin binding G-protein coupled receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane apoptosis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration response to virus coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity initiation of viral infection cell leading edge myosin light chain binding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway Endocytosis Axon guidance Leukocyte transendothelial migration
239762_at	-0.193	6.519	-2.180	4.537e-02	0.378	-4.028	LOC286437	hypothetical protein LOC286437	X		AI080505	286437	Xq22.2	Hs.656786	1
225820_at	-0.401	6.981	-2.180	4.538e-02	0.378	-4.028	PHF17	PHD finger protein 17	4	129950228, 129950228	AV646599	79960	4q26-q27	Hs.12420	14	histone acetyltransferase complex protein binding nucleus cytoplasm apoptosis response to stress zinc ion binding negative regulation of cell growth histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation regulation of transcription metal ion binding
208980_s_at	-0.408	12.542	-2.180	4.539e-02	0.378	-4.029	UBC	ubiquitin C	12	-123962144	M26880	7316	12q24.3	Hs.520348	226		PPAR signaling pathway
229518_at	0.232	4.434	2.180	4.540e-02	0.378	-4.029	FAM46B	family with sequence similarity 46, member B	1	-27204099	AA531023	115572	1p36.11	Hs.632378	7
222580_at	-0.442	7.613	-2.180	4.540e-02	0.378	-4.029	ZNF644	zinc finger protein 644	1	-91153444, -91153444	AK023596	84146	1p22.2	Hs.173001	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
222855_s_at	0.261	4.377	2.180	4.540e-02	0.378	-4.029	TRPV2	transient receptor potential cation channel, subfamily V, member 2	17	16259612	BF058747	51393	17p11.2	Hs.279746	18	calcium channel activity calcium ion binding intracellular cytoplasm plasma membrane integral to plasma membrane ion transport calcium ion transport sensory perception response to temperature stimulus melanosome
212088_at	-0.262	7.792	-2.179	4.547e-02	0.379	-4.030	PMPCA	peptidase (mitochondrial processing) alpha	9	138424936	BF570122	23203	9q34.3	Hs.495471	10	metalloendopeptidase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix proteolysis peptidase activity zinc ion binding metal ion binding
211470_s_at	0.261	2.829	2.179	4.548e-02	0.379	-4.030	SULT1C2	sulfotransferase family, cytosolic, 1C, member 2	2	108271526	AF186255	6819	2q11.1-q11.2	Hs.436123	19	cytoplasm cytoskeleton sulfotransferase activity amine metabolic process transferase activity
231112_at	-0.246	4.803	-2.178	4.550e-02	0.379	-4.031	SNRPE	small nuclear ribonucleoprotein polypeptide E	1	202097362	AU144102	6635	1q32	Hs.334612 Hs.654418	43	spliceosome assembly spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytosol RNA splicing small nuclear ribonucleoprotein complex
242297_at	0.295	5.750	2.178	4.550e-02	0.379	-4.031	RREB1	ras responsive element binding protein 1	6	7053186	BF904033	6239	6p25	Hs.298248	13	DNA binding intracellular nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter Ras protein signal transduction multicellular organismal development zinc ion binding transcription activator activity nuclear speck metal ion binding
210223_s_at	0.313	5.092	2.178	4.552e-02	0.379	-4.031	MR1	major histocompatibility complex, class I-related	1	179269761	AF010446	3140	1q25.3	Hs.101840	11	antigen processing and presentation of peptide antigen via MHC class I extracellular region endoplasmic reticulum plasma membrane immune response integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex
1553101_a_at	-0.437	8.478	-2.178	4.555e-02	0.379	-4.032	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)	17	18027591	NM_017758	54890	17p11.2	Hs.462392	5	membrane integral to membrane
1556006_s_at	-0.516	4.313	-2.178	4.555e-02	0.379	-4.032	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	BQ025347	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
213694_at	-0.468	6.555	-2.178	4.555e-02	0.379	-4.032	RSBN1	round spermatid basic protein 1	1	-114105976	AW027347	54665	1p13.2	Hs.486285	6	protein binding nucleus
205174_s_at	-1.113	4.526	-2.178	4.557e-02	0.379	-4.032	QPCT	glutaminyl-peptide cyclotransferase	2	37425256	NM_012413	25797	2p22.2	Hs.79033	15	protein modification process proteolysis peptidase activity zinc ion binding acyltransferase activity glutaminyl-peptide cyclotransferase activity transferase activity metal ion binding
205557_at	0.300	4.642	2.177	4.560e-02	0.379	-4.033	BPI	bactericidal/permeability-increasing protein	20	36365965	NM_001725	671	20q11.23-q12	Hs.529019	36	lipopolysaccharide binding extracellular region integral to plasma membrane lipid binding membrane negative regulation of interleukin-6 production negative regulation of interleukin-8 production negative regulation of tumor necrosis factor production defense response to bacterium negative regulation of macrophage activation
217556_at	-0.515	4.514	-2.177	4.564e-02	0.380	-4.033	CLCN4	chloride channel 4	X	10084984	W26966	1183	Xp22.3	Hs.495674	17	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding
202823_at	-0.421	8.055	-2.177	4.565e-02	0.380	-4.033	TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8	-75021187	N89607	6921	8q21.11	Hs.554594	46	protein binding nucleus nucleoplasm cytosol regulation of transcription from RNA polymerase II promoter ubiquitin-dependent protein catabolic process interspecies interaction between organisms regulation of transcription	Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma
233813_at	0.463	4.567	2.177	4.565e-02	0.380	-4.034	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AK026900	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
239313_at	-0.299	5.369	-2.176	4.567e-02	0.380	-4.034	LOC401320	hypothetical LOC401320	7		AI803568	401320	7p15.1	Hs.561708	2
210625_s_at	0.388	7.592	2.176	4.568e-02	0.380	-4.034	AKAP1	A kinase (PRKA) anchor protein 1	17	52517551	U34074	8165	17q21-q23	Hs.463506	27	RNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane membrane integral to membrane
208507_at	0.345	5.544	2.176	4.571e-02	0.380	-4.035	OR7C2	olfactory receptor, family 7, subfamily C, member 2	19	14913300	NM_012377	26658	19p13.1	Hs.589620	5	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
237470_at	-0.217	3.205	-2.176	4.571e-02	0.380	-4.035	DOCK7	dedicator of cytokinesis 7	1	-62692984	R45067	85440	1p31.3	Hs.406156	15	microtubule cytoskeleton organization guanyl-nucleotide exchange factor activity GTP binding multicellular organismal development nervous system development axonogenesis cell differentiation axon growth cone neuron projection development activation of Rac GTPase activity positive regulation of peptidyl-serine phosphorylation basal part of cell establishment of neuroblast polarity Rac GTPase binding GTPase binding
222449_at	-0.483	7.197	-2.176	4.572e-02	0.380	-4.035	PMEPA1	prostate transmembrane protein, androgen induced 1	20	-55656857, -55656857, -55656857	AL035541	56937	20q13.31 20q13.31-q13.33	Hs.517155	12	molecular_function plasma membrane integral to membrane androgen receptor signaling pathway WW domain binding
230661_at	0.206	3.557	2.176	4.572e-02	0.380	-4.035	C8orf84	chromosome 8 open reading frame 84	8	-74139333	AW451999	157869	8q21.11	Hs.439040	3	scavenger receptor activity extracellular region immune response polysaccharide binding
228469_at	0.387	8.290	2.176	4.573e-02	0.380	-4.035	PPID	peptidylprolyl isomerase D	4	-159849728	BF431902	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
231975_s_at	-0.467	5.472	-2.176	4.575e-02	0.380	-4.035	MIER3	mesoderm induction early response 1, family member 3	5	-56251185	AK002183	166968	5q11.2	Hs.657594	7	DNA binding nucleus regulation of transcription
209843_s_at	0.307	6.229	2.175	4.577e-02	0.380	-4.036	SOX10	SRY (sex determining region Y)-box 10	22	-36698264	BC002824	6663	22q13.1	Hs.376984	46	in utero embryonic development DNA binding chromatin binding RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity nucleus cytoplasm peripheral nervous system development cell differentiation melanocyte differentiation identical protein binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter cell maturation enteric nervous system development gut morphogenesis developmental growth oligodendrocyte differentiation
1558846_at	0.285	2.802	2.175	4.577e-02	0.380	-4.036	PNLIPRP3	pancreatic lipase-related protein 3	10	118177413	AL833418	119548	10q25.3	Hs.276724	1	triacylglycerol lipase activity extracellular region lipid catabolic process hydrolase activity
232915_at	0.276	5.269	2.175	4.578e-02	0.380	-4.036	DDX49	DEAD (Asp-Glu-Ala-Asp) box polypeptide 49	19	18891493	AW571715	54555	19p12	Hs.143187	8	nucleotide binding RNA binding helicase activity ATP binding ATP-dependent helicase activity hydrolase activity
211296_x_at	-0.292	13.124	-2.175	4.579e-02	0.380	-4.036	UBC	ubiquitin C	12	-123962144	AB009010	7316	12q24.3	Hs.520348	226		PPAR signaling pathway
244804_at	-0.589	6.813	-2.175	4.580e-02	0.380	-4.036	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	AW293441	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
201118_at	-0.415	6.317	-2.175	4.580e-02	0.380	-4.036	PGD	phosphogluconate dehydrogenase	1	10381671	NM_002631	5226	1p36.3-p36.13	Hs.464071	11	phosphogluconate dehydrogenase (decarboxylating) activity protein binding pentose-phosphate shunt, oxidative branch oxidoreductase activity pentose biosynthetic process NADP or NADPH binding oxidation reduction	Pentose phosphate pathway Glutathione metabolism Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
226814_at	0.456	6.544	2.175	4.580e-02	0.380	-4.036	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	3	-64476370	AI431730	56999	3p14.3-p14.2	Hs.656071	23	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis glycoprotein catabolic process multicellular organismal development peptidase activity zinc ion binding metal ion binding
203775_at	-0.421	4.479	-2.175	4.582e-02	0.380	-4.037	SLC25A13	solute carrier family 25, member 13 (citrin)	7	-95587468, -95587467	NM_014251	10165	7q21.3	Hs.489190	31	transporter activity L-glutamate transmembrane transporter activity binding calcium ion binding mitochondrion mitochondrial inner membrane integral to plasma membrane ATP biosynthetic process transport L-aspartate transmembrane transporter activity aspartate transport L-glutamate transport membrane malate-aspartate shuttle cellular respiration response to calcium ion
213048_s_at	-0.321	8.639	-2.175	4.583e-02	0.380	-4.037	SET	SET nuclear oncogene	9	130485754, 130491329	W26593	6418	9q34	Hs.436687 Hs.609454	66	phosphoprotein phosphatase inhibitor activity nucleus nucleoplasm cytoplasm endoplasmic reticulum cytosol DNA replication nucleosome assembly nucleosome disassembly nucleocytoplasmic transport protein phosphatase type 2A regulator activity negative regulation of histone acetylation histone binding perinuclear region of cytoplasm
229176_at	-0.369	5.700	-2.175	4.583e-02	0.380	-4.037	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	AI672354	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
217118_s_at	-0.757	6.156	-2.175	4.584e-02	0.380	-4.037	C22orf9	chromosome 22 open reading frame 9	22	-43966786, -43966786	AK025608	23313	22q13.31	Hs.592207	10	protein binding
229565_x_at	0.255	4.057	2.174	4.585e-02	0.380	-4.037	TBX3	T-box 3	12	-113592441	N29712	6926	12q24.1	Hs.714737	28	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis multicellular organismal development cell aging positive regulation of cell proliferation determination of anterior/posterior axis, embryo organ morphogenesis general transcriptional repressor activity male genitalia development female genitalia development mammary gland development luteinizing hormone secretion embryonic arm morphogenesis forelimb morphogenesis embryonic digit morphogenesis sequence-specific DNA binding negative regulation of myoblast differentiation positive regulation of cell cycle negative regulation of transcription, DNA-dependent follicle-stimulating hormone secretion mesoderm morphogenesis
214890_s_at	-0.768	5.468	-2.174	4.585e-02	0.380	-4.037	FAM149A	family with sequence similarity 149, member A	4	187302988, 187307320	AL080065	25854	4q35.1	Hs.357025	3
1554093_a_at	-0.339	8.125	-2.174	4.586e-02	0.380	-4.037	SNAPC5	small nuclear RNA activating complex, polypeptide 5, 19kDa	15	-64569719	BC014315	10302	15q22.31	Hs.30174	7	transcription factor activity nucleus transcription from RNA polymerase II promoter transcription initiation from RNA polymerase III promoter regulation of transcription
1560974_s_at	0.585	5.035	2.174	4.589e-02	0.380	-4.038	NOS1	nitric oxide synthase 1 (neuronal)	12	-116135361	BF447723	4842	12q24.2-q24.31	Hs.654410	188	response to hypoxia photoreceptor inner segment nitric-oxide synthase activity calmodulin binding cytoplasm cytoskeleton arginine catabolic process nitric oxide biosynthetic process myoblast fusion electron carrier activity response to heat FMN binding negative regulation of calcium ion transport into cytosol oxidoreductase activity sarcoplasmic reticulum heme binding multicellular organismal response to stress tetrahydrobiopterin binding arginine binding neurotransmitter biosynthetic process sarcolemma cell projection dendritic spine positive regulation of vasodilation positive regulation of vasodilation cadmium ion binding metal ion binding perinuclear region of cytoplasm FAD binding NADP or NADPH binding oxidation reduction regulation of cardiac muscle contraction	Arginine and proline metabolism Metabolic pathways Calcium signaling pathway Long-term depression Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer Small cell lung cancer
224737_x_at	-0.305	7.429	-2.174	4.589e-02	0.380	-4.038	CCAR1	cell division cycle and apoptosis regulator 1	10	70150976	BG541830	55749	10q21.3	Hs.49853	18	nuclear mRNA splicing, via spliceosome nucleic acid binding nucleus cytoplasm Golgi apparatus apoptosis cell cycle perinuclear region of cytoplasm
227672_at	0.244	6.666	2.174	4.590e-02	0.380	-4.038	C8orf73	chromosome 8 open reading frame 73	8	-144719505	W67308	642475	8q24.3	Hs.531406	3	binding Golgi apparatus
221918_at	-0.313	7.545	-2.174	4.590e-02	0.380	-4.038	PCTK2	PCTAIRE protein kinase 2	12	-95196170	AI742210	5128	12q23.1	Hs.506415	11	nucleotide binding cyclin-dependent protein kinase activity ATP binding protein amino acid phosphorylation transferase activity
225594_at	-0.498	6.589	-2.174	4.591e-02	0.380	-4.039	CREBZF	CREB/ATF bZIP transcription factor	11	-85046257	AL038866	58487	11q14	Hs.535319 Hs.595940 Hs.714910	12	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent response to virus negative regulation of transcription specific transcriptional repressor activity sequence-specific DNA binding negative regulation of gene expression, epigenetic regulation of transcription factor activity
225418_at	0.232	6.457	2.174	4.592e-02	0.380	-4.039	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	19	50041232, 50041232	AI520949	5819	19q13.2	Hs.655455	38	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of immunoglobulin mediated immune response plasma membrane cell-cell junction zonula adherens cell adhesion homophilic cell adhesion spermatid development cell surface coreceptor activity integral to membrane viral envelope fusion with host membrane positive regulation of mast cell activation susceptibility to natural killer cell mediated cytotoxicity virion attachment, binding of host cell surface coreceptor cell adhesion molecule binding adhesion to symbiont susceptibility to T cell mediated cytotoxicity	Cell adhesion molecules (CAMs) Adherens junction
235402_at	0.255	5.136	2.174	4.592e-02	0.380	-4.039	C11orf66	chromosome 11 open reading frame 66	11	61005167	AI866146	220004	11q12.2	Hs.502726	3
213644_at	-0.415	6.059	-2.174	4.593e-02	0.380	-4.039	CCDC46	coiled-coil domain containing 46	17	-61062119, -61062119	AI979276	201134	17q24.1	Hs.408676	4
203311_s_at	-0.363	7.503	-2.173	4.597e-02	0.380	-4.040	ARF6	ADP-ribosylation factor 6	14	49429485	M57763	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
217771_at	-0.451	4.486	-2.173	4.597e-02	0.380	-4.040	GOLM1	golgi membrane protein 1	9	-87830877, -87830877	NM_016548	51280	9q21.33	Hs.494337	22	Golgi apparatus integral to plasma membrane membrane
200098_s_at	-0.319	9.329	-2.173	4.598e-02	0.380	-4.040	ANAPC5	anaphase promoting complex subunit 5	12	-120230432, -120230432	T33068	51433	12q24.31	Hs.7101	28	G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
1560006_a_at	0.257	4.754	2.173	4.599e-02	0.380	-4.040	LOC646762	hypothetical LOC646762	7	-29652063	BG501482	646762	7p14.3	Hs.30579	2
212514_x_at	-0.535	6.111	-2.173	4.601e-02	0.380	-4.040	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	X	41077594	R60068	1654	Xp11.3-p11.23	Hs.719127	34	nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus cytoplasm plasma membrane nuclear speck hydrolase activity interspecies interaction between organisms	RIG-I-like receptor signaling pathway
232181_at	0.497	7.420	2.173	4.601e-02	0.380	-4.040	LOC153346	hypothetical protein LOC153346	5		AU157049	153346	5q33.1	Hs.483816	1
204806_x_at	0.355	8.027	2.173	4.601e-02	0.380	-4.040	HLA-F	major histocompatibility complex, class I, F	6	29799095, 29799095, 1143812, 1143812, 945922, 945922	NM_018950	3134	6p21.3	Hs.519972	68	antigen processing and presentation of peptide antigen via MHC class I immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
225866_at	-0.323	8.184	-2.172	4.608e-02	0.381	-4.042	BXDC1	brix domain containing 1	6	111409983	AA976536	84154	6q21	Hs.372265	8	protein binding nucleus nucleolus
201156_s_at	-0.248	5.787	-2.172	4.609e-02	0.381	-4.042	RAB5C	RAB5C, member RAS oncogene family	17	-37530522	AF141304	5878	17q21.2	Hs.650382	11	nucleotide binding GTPase activity protein binding GTP binding endosome plasma membrane endosome organization small GTPase mediated signal transduction protein transport regulation of endocytosis endocytic vesicle melanosome	Endocytosis
206692_at	0.249	2.995	2.171	4.613e-02	0.381	-4.043	KCNJ10	potassium inwardly-rectifying channel, subfamily J, member 10	1	-158274656	NM_002241	3766	1q22-q23	Hs.408960	25	nucleotide binding voltage-gated ion channel activity potassium channel activity protein binding ATP binding integral to plasma membrane ion transport potassium ion transport ATP-activated inward rectifier potassium channel activity membrane potassium ion binding
221295_at	0.234	4.973	2.171	4.613e-02	0.381	-4.043	CIDEA	cell death-inducing DFFA-like effector a	18	12244317, 12244627	NM_001279	1149	18 18p11.21	Hs.249129	15	temperature homeostasis protein binding intracellular nucleus cytoplasm mitochondrion mitochondrial envelope lipid particle DNA fragmentation involved in apoptosis lipid metabolic process cell death DNA damage response, signal transduction resulting in induction of apoptosis positive regulation of sequestering of triglyceride lipid storage negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of tumor necrosis factor production protein homodimerization activity negative regulation of apoptosis negative regulation of cytokine secretion negative regulation of lipid catabolic process
242178_at	0.238	2.847	2.171	4.615e-02	0.381	-4.043	LIPI	lipase, member I	21	-14403005	AA528339	149998	21q11.2	Hs.139907	4	extracellular region lipid catabolic process hydrolase activity
225589_at	-0.450	5.587	-2.171	4.616e-02	0.381	-4.043	SH3RF1	SH3 domain containing ring finger 1	4	-170251981	AB040927	57630	4q32.3-q33	Hs.301804	9	protein binding cytoplasm Golgi apparatus zinc ion binding ligase activity lamellipodium metal ion binding perinuclear region of cytoplasm
211845_at	0.294	5.252	2.171	4.616e-02	0.381	-4.043	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	11	-119050308, -119036912, -119014017	AF110314	5818	11q23.3	Hs.334846	42	extracellular region plasma membrane cell-cell adherens junction immune response homophilic cell adhesion heterophilic cell adhesion coreceptor activity integral to membrane protein homodimerization activity interspecies interaction between organisms entry of virus into host cell cell adhesion molecule binding	Cell adhesion molecules (CAMs) Adherens junction
231868_at	0.259	3.509	2.171	4.619e-02	0.381	-4.044	HOMEZ	homeobox and leucine zipper encoding	14	-22812683	AA916857	57594	14q11.2	Hs.632332	7	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
225186_at	-0.406	4.850	-2.171	4.619e-02	0.381	-4.044	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	2	-204014436, -204006783	BF114947	65059	2q33	Hs.471162	13	nucleus cytoplasm cytoskeleton plasma membrane cell-matrix adhesion signal transduction lamellipodium filopodium
203482_at	-0.360	6.631	-2.170	4.619e-02	0.381	-4.044	FAM178A	family with sequence similarity 178, member A	10	102662315, 102662315, 102662315	AL133215	55719	10q24.31	Hs.447458	5
204845_s_at	0.457	3.300	2.170	4.621e-02	0.381	-4.044	ENPEP	glutamyl aminopeptidase (aminopeptidase A)	4	111616677	NM_001977	2028	4q25	Hs.435765	25	angiogenesis aminopeptidase activity calcium ion binding plasma membrane integral to plasma membrane brush border proteolysis cell-cell signaling peptidase activity metalloexopeptidase activity zinc ion binding cell proliferation external side of plasma membrane apical plasma membrane cell migration cytoplasmic vesicle	Renin-angiotensin system
217952_x_at	-0.444	7.112	-2.170	4.622e-02	0.381	-4.044	PHF3	PHD finger protein 3	6	64414389	BF430956	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
229364_at	0.275	5.156	2.170	4.623e-02	0.381	-4.045	LOC646870	hypothetical protein LOC646870	1		AI979338	646870	1q25.1
222623_s_at	-0.445	7.764	-2.170	4.627e-02	0.381	-4.045	ZNF639	zinc finger protein 639	3	180524244	BF001614	51193	3q26.33	Hs.632578	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
216233_at	0.238	2.194	2.170	4.627e-02	0.381	-4.045	CD163	CD163 molecule	12	-7514676	Z22970	9332	12p13.3	Hs.504641	51	scavenger receptor activity protein binding extracellular region plasma membrane integral to plasma membrane acute-phase response inflammatory response
212850_s_at	-0.581	5.496	-2.170	4.628e-02	0.381	-4.045	LRP4	low density lipoprotein receptor-related protein 4	11	-46834993	AA584297	4038	11p11.2-p12	Hs.4930	7	receptor activity calcium ion binding cellular_component endocytosis biological_process membrane integral to membrane
241813_at	-0.551	5.183	-2.170	4.628e-02	0.381	-4.045	MBD1	methyl-CpG binding domain protein 1	18	-46049213	BG252318	4152	18q21	Hs.405610	40	transcription factor activity transcription corepressor activity protein binding nucleus transcription from RNA polymerase II promoter zinc ion binding methyl-CpG binding negative regulation of transcription nuclear speck metal ion binding
227900_at	-0.372	4.576	-2.169	4.628e-02	0.381	-4.045	CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	3	-106859798	AV701750	868	3q13.11	Hs.430589	44	signal transducer activity calcium ion binding protein binding nucleus cytoplasm NLS-bearing substrate import into nucleus immune response cell surface receptor linked signal transduction zinc ion binding ligase activity modification-dependent protein catabolic process	ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis Jak-STAT signaling pathway T cell receptor signaling pathway Insulin signaling pathway Pathways in cancer Chronic myeloid leukemia
1553682_at	0.276	3.600	2.169	4.630e-02	0.381	-4.046	FBXL14	F-box and leucine-rich repeat protein 14	12	-1545420	NM_152441	144699	12p13.33	Hs.367956	3	modification-dependent protein catabolic process
226333_at	-0.716	7.149	-2.169	4.630e-02	0.381	-4.046	IL6R	interleukin 6 receptor	1	152644292	AV700030	3570	1q21	Hs.709210	132	hepatic immune response monocyte chemotaxis positive regulation of leukocyte chemotaxis receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity receptor binding extracellular region plasma membrane interleukin-6 receptor complex acute-phase response integral to membrane apical plasma membrane enzyme binding endocrine pancreas development endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production response to cytokine stimulus positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity regulation of apoptosis positive regulation of osteoblast differentiation positive regulation of anti-apoptosis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium interleukin-6-mediated signaling pathway ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
201649_at	0.408	6.531	2.169	4.631e-02	0.381	-4.046	UBE2L6	ubiquitin-conjugating enzyme E2L 6	11	-57075704, -57075704	NM_004223	9246	11q12	Hs.425777	19	ubiquitin-protein ligase activity protein binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
206366_x_at	0.236	4.333	2.169	4.632e-02	0.381	-4.046	XCL1	chemokine (C motif) ligand 1	1	166812479	U23772	6375	1q23	Hs.546295	39	extracellular region extracellular space cellular calcium ion homeostasis chemotaxis immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
232490_s_at	0.201	4.874	2.169	4.633e-02	0.381	-4.046	PRUNE	prune homolog (Drosophila)	1	149247596	U67085	58497	1q21	Hs.78524	8	inorganic diphosphatase activity protein binding nucleus cytoplasm focal adhesion hydrolase activity cell junction manganese ion binding metal ion binding	Purine metabolism
224452_s_at	-0.603	9.919	-2.169	4.633e-02	0.381	-4.046	C7orf70	chromosome 7 open reading frame 70	7	-6335564	BC006110	84792	7p22.1	Hs.696146	4	nucleus
219381_at	0.355	3.372	2.169	4.637e-02	0.381	-4.047	C5orf42	chromosome 5 open reading frame 42	5	-37142086	NM_023073	65250	5p13.2	Hs.170993 Hs.586199 Hs.643420 Hs.649870 Hs.649889 Hs.705282	4	membrane integral to membrane
224736_at	-0.371	7.832	-2.168	4.638e-02	0.381	-4.047	CCAR1	cell division cycle and apoptosis regulator 1	10	70150976	BE617899	55749	10q21.3	Hs.49853	18	nuclear mRNA splicing, via spliceosome nucleic acid binding nucleus cytoplasm Golgi apparatus apoptosis cell cycle perinuclear region of cytoplasm
220385_at	-0.283	5.712	-2.168	4.638e-02	0.381	-4.047	JPH2	junctophilin 2	20	-42238870, -42173750	NM_020433	57158	20q13.12	Hs.441737	11	protein binding membrane fraction microsome plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
219423_x_at	0.454	4.158	2.168	4.639e-02	0.381	-4.047	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	1	-6446757, -6443800	NM_003790	8718	1p36.2	Hs.462529	30	receptor activity tumor necrosis factor receptor activity protein binding extracellular region cytosol plasma membrane integral to plasma membrane cell surface receptor linked signal transduction induction of apoptosis by extracellular signals regulation of apoptosis	Cytokine-cytokine receptor interaction
226346_at	0.278	4.704	2.168	4.639e-02	0.381	-4.047	MEX3A	mex-3 homolog A (C. elegans)	1	-154308427	AA527151	92312	1q22	Hs.591496	3	cytoplasmic mRNA processing body RNA binding protein binding nucleus cytoplasm zinc ion binding metal ion binding
209690_s_at	0.321	4.329	2.168	4.641e-02	0.381	-4.048	DOK4	docking protein 4	16	-56063370	BF591163	55715	16q21	Hs.279832	11	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
210802_s_at	-0.351	6.511	-2.168	4.644e-02	0.382	-4.048	DIMT1L	DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)	5	-61720107	BC002841	27292	5q11-q14	Hs.719162	6	rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity RNA binding nucleus nucleolus methyltransferase activity transferase activity
1557734_s_at	0.250	3.275	2.168	4.645e-02	0.382	-4.049	LOC100130548	hypothetical protein LOC100130548	9		AL044130	100130548	9q34.2	Hs.671096	1
235299_at	-0.187	2.423	-2.168	4.646e-02	0.382	-4.049	SLC41A2	solute carrier family 41, member 2	12	-103721404	AI769269	84102	12q23.3	Hs.577463	6	magnesium ion binding plasma membrane cation transport cation transmembrane transporter activity integral to membrane
218656_s_at	0.327	7.726	2.167	4.648e-02	0.382	-4.049	LHFP	lipoma HMGIC fusion partner	13	-38815028	NM_005780	10186	13q12	Hs.507798	8	DNA binding membrane integral to membrane
224948_at	0.252	11.648	2.167	4.650e-02	0.382	-4.050	MRPS24	mitochondrial ribosomal protein S24	7	-43872681	BF970023	64951	7p14	Hs.284286	11	molecular_function structural constituent of ribosome protein binding mitochondrion mitochondrial large ribosomal subunit mitochondrial small ribosomal subunit ribosome translation biological_process
214340_at	0.251	5.040	2.167	4.652e-02	0.382	-4.050	ALOX12P2	arachidonate 12-lipoxygenase pseudogene 2	17	6697618	AF020774	245	17p13	Hs.378695	3
216965_x_at	0.217	6.086	2.167	4.652e-02	0.382	-4.050	SPG20	spastic paraplegia 20 (Troyer syndrome)	13	-35773776, -35773776, -35773776	AL139377	23111	13q13.3	Hs.440414	19	cell death
204272_at	0.535	4.112	2.167	4.652e-02	0.382	-4.050	LGALS4	lectin, galactoside-binding, soluble, 4	19	-43984150	NM_006149	3960	19q13.2	Hs.5302	14	protein binding sugar binding cytosol plasma membrane cell adhesion
235245_at	0.287	5.176	2.167	4.653e-02	0.382	-4.050	TMEM92	transmembrane protein 92	17	45706831	AI990471	162461	17q21.33	Hs.224630	4	membrane integral to membrane
1555337_a_at	0.273	3.189	2.167	4.654e-02	0.382	-4.050	ZNF317	zinc finger protein 317	19	9112085	AF307097	57693		Hs.465829	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
233870_at	0.207	5.218	2.166	4.656e-02	0.382	-4.051	NAV1	neuron navigator 1	1	199884072	AB033039	89796	1q32.3	Hs.585374	10	nucleotide binding cytoplasm cytoskeleton microtubule multicellular organismal development nervous system development nucleoside-triphosphatase activity cell differentiation
1559114_a_at	0.190	3.878	2.166	4.659e-02	0.382	-4.051	CXCR7	chemokine (C-X-C motif) receptor 7	2	237143118	BC038720	57007	2q37.3	Hs.471751	21	receptor activity G-protein coupled receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane interspecies interaction between organisms
60084_at	-0.301	3.429	-2.166	4.660e-02	0.382	-4.051	CYLD	cylindromatosis (turban tumor syndrome)	16	49333461, 49333529	AI453099	1540	16q12.1	Hs.578973	54	structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm	RIG-I-like receptor signaling pathway
207257_at	0.207	4.767	2.166	4.661e-02	0.382	-4.052	EPO	erythropoietin	7	100156358	NM_000799	2056	7q22	Hs.2303	177	response to hypoxia erythropoietin receptor binding hormone activity protein binding extracellular region extracellular space regulation of transcription from RNA polymerase II promoter apoptosis signal transduction embryo implantation blood circulation positive regulation of cell proliferation erythrocyte differentiation positive regulation of tyrosine phosphorylation of Stat5 protein hemoglobin biosynthetic process positive regulation of gene-specific transcription erythrocyte maturation positive regulation of DNA replication positive regulation of Ras protein signal transduction	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
224631_at	-0.411	6.839	-2.166	4.662e-02	0.382	-4.052	ZFP91	zinc finger protein 91 homolog (mouse)	11	58103162	AA758013	80829	11q12	Hs.524920	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1555659_a_at	0.256	5.232	2.165	4.665e-02	0.382	-4.052	TREML1	triggering receptor expressed on myeloid cells-like 1	6	-41225319	AF534823	340205	6p21.1	Hs.117331	14	receptor activity protein binding cytoplasm plasma membrane cell surface integral to membrane integral to membrane platelet activation platelet alpha granule innate immune response
213966_at	0.203	4.575	2.165	4.667e-02	0.382	-4.053	HMG20B	high-mobility group 20B	19	3523942	N25429	10362	19p13.3	Hs.406534	18	transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle chromatin modification
217294_s_at	-0.544	7.776	-2.165	4.668e-02	0.382	-4.053	ENO1	enolase 1, (alpha)	1	-8843649	U88968	2023	1p36.3-p36.2	Hs.517145	69	phosphopyruvate hydratase complex negative regulation of transcription from RNA polymerase II promoter magnesium ion binding transcription factor activity transcription corepressor activity serine-type endopeptidase activity phosphopyruvate hydratase activity protein binding nucleus cytoplasm plasma membrane glycolysis lyase activity negative regulation of cell growth M band regulation of transcription	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways RNA degradation
1552576_at	0.273	3.870	2.165	4.669e-02	0.382	-4.053	ALMS1P	Alstrom syndrome 1 pseudogene	2	73725553	NM_145300	200420	2p13.1	Hs.278983	2
219097_x_at	-0.272	7.127	-2.164	4.673e-02	0.382	-4.054	C19orf42	chromosome 19 open reading frame 42	19	-16617958	NM_024104	79086	19p13.11	Hs.356467	1	membrane integral to membrane
238058_at	-0.434	9.301	-2.164	4.677e-02	0.383	-4.055	LOC150381	hypothetical LOC150381	22	44828389	AA603041	150381	22q13.31	Hs.659113	1
205637_s_at	0.283	4.831	2.164	4.678e-02	0.383	-4.055	SH3GL3	SH3-domain GRB2-like 3	15	81907094	NM_003027	6457	15q24	Hs.270055 Hs.666365	25	cytoplasm endosome endocytosis signal transduction central nervous system development lipid binding membrane identical protein binding	Endocytosis
205444_at	-1.282	10.528	-2.164	4.679e-02	0.383	-4.055	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	16	28797309	NM_004320	487	16p12.1	Hs.657344	41	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding protein binding ATP binding microsome ATP biosynthetic process cation transport metabolic process apoptotic mitochondrial changes membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances positive regulation of fast-twitch skeletal muscle fiber contraction elevation of endoplasmic reticulum calcium ion concentration reduction of endoplasmic reticulum calcium ion concentration sarcoplasmic reticulum membrane sarcoplasmic reticulum membrane calcium channel complex response to endoplasmic reticulum stress protein homodimerization activity elevation of mitochondrial calcium ion concentration maintenance of mitochondrion location apoptosis in response to endoplasmic reticulum stress calcium ion import	Calcium signaling pathway Alzheimer's disease
243027_at	0.267	2.633	2.164	4.679e-02	0.383	-4.055	IGSF5	immunoglobulin superfamily, member 5	21	40039203	AI824021	150084	21q22.2	Hs.422120	3	plasma membrane tight junction integral to membrane cell junction	Tight junction Epithelial cell signaling in Helicobacter pylori infection
212093_s_at	-0.541	7.051	-2.164	4.679e-02	0.383	-4.055	MTUS1	mitochondrial tumor suppressor 1	8	-17545583, -17545583, -17545583	AI695017	57509	8p22	Hs.7946	11	nucleus mitochondrion Golgi apparatus plasma membrane
1565337_at	0.199	2.730	2.163	4.682e-02	0.383	-4.055	DNAH6	dynein, axonemal, heavy chain 6	2	84597089	AJ132086	1768	2p11.2	Hs.249972	7	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement ATPase activity dynein complex
225004_at	-0.285	6.971	-2.163	4.684e-02	0.383	-4.056	TMEM101	transmembrane protein 101	17	-39444081	AL525613	84336	17q21.31	Hs.514211	3	signal transducer activity cellular_component membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
1552639_at	0.282	4.947	2.163	4.687e-02	0.383	-4.056	KLHDC7B	kelch domain containing 7B	22	49333327	NM_138433	113730	22q13.33	Hs.137007	3
213064_at	-0.432	6.460	-2.163	4.687e-02	0.383	-4.056	ZC3H14	zinc finger CCCH-type containing 14	14	88099005, 88099443, 88130482	N64802	79882	14q31.3	Hs.325846	7	RNA binding nucleus zinc ion binding metal ion binding
238689_at	0.252	2.960	2.163	4.687e-02	0.383	-4.056	GPR110	G protein-coupled receptor 110	6	-47095580, -47075771	BG426455	266977	6p12.3	Hs.256897	11	G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
240301_at	0.249	3.841	2.163	4.688e-02	0.383	-4.057	DPPA2	developmental pluripotency associated 2	3	-110495325	AI204212	151871	3q13.13	Hs.351113	6	nucleic acid binding nucleus
1553551_s_at	0.203	13.655	2.162	4.691e-02	0.383	-4.057	ND2	MTND2	MT		NM_173709	4536			43	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane oxidoreductase activity electron transport chain ATP synthesis coupled electron transport respiratory chain	Oxidative phosphorylation Metabolic pathways Parkinson's disease
228383_at	-0.353	5.970	-2.162	4.696e-02	0.383	-4.058	PNPLA7	patatin-like phospholipase domain containing 7	9	-139474225	AK024443	375775	9q34.3	Hs.294147	6	nucleus mitochondrion lysosome endoplasmic reticulum microsome lipid metabolic process metabolic process membrane integral to membrane hydrolase activity
200668_s_at	-0.404	9.995	-2.162	4.696e-02	0.383	-4.058	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	4	-103936216, -103936216, -103936216, -103936216, -103936216, -103936216	BC003395	7323	4q24	Hs.518773	28	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity BMP signaling pathway regulation of protein metabolic process	Ubiquitin mediated proteolysis
201803_at	-0.248	9.216	-2.162	4.696e-02	0.383	-4.058	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	4	57539865	NM_000938	5431	4q12	Hs.602757	92	magnesium ion binding nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
214659_x_at	-0.534	6.421	-2.162	4.697e-02	0.383	-4.058	YLPM1	YLP motif containing 1	14	74299821	AC007956	56252	14q24.3	Hs.531111	11	molecular_function cellular_component nucleus biological_process nuclear speck
202164_s_at	-0.499	5.757	-2.162	4.697e-02	0.383	-4.058	CNOT8	CCR4-NOT transcription complex, subunit 8	5	154218390	AF180476	9337	5q31-q33	Hs.26703	16	nucleic acid binding transcription factor activity protein binding intracellular nucleus cytoplasm regulation of transcription, DNA-dependent negative regulation of cell proliferation	RNA degradation
218815_s_at	0.215	5.326	2.161	4.699e-02	0.383	-4.059	TMEM51	transmembrane protein 51	1	15351614, 15352815	NM_018022	55092	1p36.21	Hs.465305	5	membrane integral to membrane
243277_x_at	0.178	2.290	2.161	4.700e-02	0.383	-4.059	MECOM	MDS1 and EVI1 complex locus	3	-170283980, -170283980, -170283980, -170283980	AI458437	2122	3q24-q28	Hs.659873 Hs.719216	46	molecular_function DNA binding transcription factor activity protein binding intracellular nucleus multicellular organismal development biological_process zinc ion binding metal ion binding	MAPK signaling pathway Pathways in cancer Chronic myeloid leukemia
206099_at	0.209	5.859	2.161	4.706e-02	0.383	-4.060	PRKCH	protein kinase C, eta	14	60858267	NM_006255	5583	14q22-q23	Hs.333907	65	nucleotide binding protein kinase C activity ATP binding protein amino acid phosphorylation intracellular signaling cascade zinc ion binding transferase activity enzyme binding diacylglycerol binding metal ion binding	Vascular smooth muscle contraction Tight junction
220023_at	0.227	4.280	2.161	4.706e-02	0.383	-4.060	APOB48R	apolipoprotein B48 receptor	16	28413493	NM_018690	55911	16p11	Hs.200333	4	receptor activity plasma membrane lipid metabolic process triglyceride metabolic process lipid transport steroid metabolic process cholesterol metabolic process very-low-density lipoprotein receptor activity very-low-density lipoprotein particle low-density lipoprotein particle chylomicron
224825_at	-0.389	7.468	-2.161	4.706e-02	0.383	-4.060	DNTTIP1	deoxynucleotidyltransferase, terminal, interacting protein 1	20	43853982	AL050348	116092	20q13.12	Hs.472852	7	nucleus
218128_at	-0.475	5.937	-2.161	4.707e-02	0.383	-4.060	NFYB	nuclear transcription factor Y, beta	12	-103034987	AU151875	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
231301_at	-0.207	2.101	-2.161	4.708e-02	0.383	-4.060	NUP54	nucleoporin 54kDa	4	-77254840	BE671244	53371	4q21.1	Hs.430435	16	nucleocytoplasmic transporter activity protein binding nucleus nuclear pore nucleoplasm cytoplasm protein targeting nucleocytoplasmic transport protein transport membrane mRNA transport intracellular protein transmembrane transport
220752_at	0.252	2.655	2.160	4.711e-02	0.383	-4.061	LOC51145	erythrocyte transmembrane protein	9		NM_016158	51145	9q33.3	Hs.104671 Hs.719591
212169_at	0.360	8.166	2.160	4.711e-02	0.383	-4.061	FKBP9	FK506 binding protein 9, 63 kDa	7	32963529	AL050187	11328	7p11.1	Hs.103934	7	peptidyl-prolyl cis-trans isomerase activity calcium ion binding endoplasmic reticulum protein folding isomerase activity
210855_at	0.215	4.501	2.160	4.713e-02	0.383	-4.061	GREB1	GREB1 protein	2	11591692, 11597530, 11600301	AF245390	9687	2p25.1	Hs.467733	11	membrane integral to membrane
218469_at	-0.916	4.026	-2.160	4.713e-02	0.383	-4.061	GREM1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	15	30797496	NM_013372	26585	15q13-q15	Hs.40098	28	cytokine activity protein binding extracellular region extracellular space multicellular organismal development nervous system development
236061_at	0.317	5.283	2.160	4.714e-02	0.383	-4.061	PRDM15	PR domain containing 15	21	-42094393, -42091453	BF058757	63977	21q22.3	Hs.473893 Hs.711654	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204661_at	0.352	5.109	2.160	4.717e-02	0.384	-4.062	CD52	CD52 molecule	1	26516997	NM_001803	1043	1p36	Hs.276770	27	membrane fraction plasma membrane integral to plasma membrane elevation of cytosolic calcium ion concentration anchored to membrane respiratory burst
1563533_at	0.486	5.103	2.159	4.718e-02	0.384	-4.062	GADL1	glutamate decarboxylase-like 1	3	-30742695	AL832766	339896	3p24.1-p23	Hs.657052	1	lyase activity carboxy-lyase activity carboxylic acid metabolic process pyridoxal phosphate binding
213784_at	0.244	5.530	2.159	4.720e-02	0.384	-4.062	RABL4	RAB, member of RAS oncogene family-like 4	22	-35484200	AL037167	11020	22q13.1	Hs.415172	6	nucleotide binding GTP binding small GTPase mediated signal transduction
230019_s_at	0.298	6.171	2.159	4.721e-02	0.384	-4.063	PTCHD2	patched domain containing 2	1	11461881	AW206105	57540	1p36.22	Hs.202355	6	hedgehog receptor activity membrane integral to membrane
232052_at	-0.204	6.015	-2.159	4.723e-02	0.384	-4.063	LOC440944	hypothetical LOC440944	3	-9405536	AL110136	440944	3p25.3	Hs.598958 Hs.652556	2
211469_s_at	0.256	5.158	2.159	4.724e-02	0.384	-4.063	CXCR6	chemokine (C-X-C motif) receptor 6	3	45959976	U73531	10663	3p21	Hs.34526	37	G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway
219174_at	-0.418	5.074	-2.159	4.726e-02	0.384	-4.064	IFT74	intraflagellar transport 74 homolog (Chlamydomonas)	9	26937036, 26937309, 26946370, 26946370	NM_025103	80173	9p21.2	Hs.145402	8	cytoplasmic vesicle
233561_at	0.233	2.547	2.158	4.726e-02	0.384	-4.064	SH3TC2	SH3 domain and tetratricopeptide repeats 2	5	-148341905	AK023641	79628	5q32	Hs.483784	15	binding
215752_at	0.218	3.466	2.158	4.727e-02	0.384	-4.064	SIK2	salt-inducible kinase 2	11	110978379	AK026682	23235	11q23.1	Hs.269128	14	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm Golgi apparatus protein amino acid phosphorylation protein kinase cascade transferase activity regulation of insulin receptor signaling pathway
204771_s_at	-0.374	6.755	-2.158	4.727e-02	0.384	-4.064	TTF1	transcription termination factor, RNA polymerase I	9	-134240757	AI632304	7270	9q34.13	Hs.54780	18	DNA binding transcription termination factor activity nucleus nucleoplasm nucleolus transcription termination negative regulation of DNA replication regulation of transcription
230122_at	0.315	3.275	2.158	4.728e-02	0.384	-4.064	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10	21863107, 21863579	BE219716	8028	10p12	Hs.30385	19	transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding
210129_s_at	0.261	5.838	2.158	4.728e-02	0.384	-4.064	TTLL3	tubulin tyrosine ligase-like family, member 3	3	9826903	AF078842	26140	3p25.3	Hs.709359	7	tubulin-tyrosine ligase activity cilium protein modification process microtubule cytoskeleton protein polyglycylation axoneme assembly cilium axoneme cilium assembly protein-glycine ligase activity, initiating
215266_at	0.302	5.700	2.158	4.730e-02	0.384	-4.064	DNAH3	dynein, axonemal, heavy chain 3	16	-20851976	AL096732	55567	16p12.3	Hs.526500	7	nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme	Huntington's disease
203789_s_at	-1.037	8.170	-2.158	4.731e-02	0.384	-4.064	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	7	-80209789	NM_006379	10512	7q21-q31	Hs.269109	15	neural crest cell migration blood vessel remodeling receptor activity extracellular region extracellular space immune response heart development post-embryonic development membrane semaphorin receptor binding response to drug	Axon guidance
212107_s_at	-0.344	5.151	-2.158	4.731e-02	0.384	-4.065	DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	1	181075073	BE561014	1660	1q25	Hs.191518	57	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding double-stranded RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity protein binding ATP binding intracellular nucleus nucleolus cytoplasm centrosome hydrolase activity ribonucleoprotein complex cellular response to heat
216521_s_at	-0.524	5.597	-2.158	4.732e-02	0.384	-4.065	BRCC3	BRCA1/BRCA2-containing complex, subunit 3	X	153952903	S72931	79184	Xq28	Hs.558537	19	nuclear ubiquitin ligase complex ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding nucleus double-strand break repair response to DNA damage stimulus peptidase activity metallopeptidase activity zinc ion binding response to X-ray chromatin modification modification-dependent protein catabolic process enzyme regulator activity G2/M transition DNA damage checkpoint polyubiquitin binding positive regulation of DNA repair metal ion binding BRCA1-A complex histone H2A K63-linked deubiquitination histone H2A K63-linked deubiquitination BRISC complex
212375_at	-0.241	6.623	-2.158	4.733e-02	0.384	-4.065	EP400	E1A binding protein p400	12	131000460	AL563727	57634	12q24.33	Hs.699245	19	nucleotide binding DNA binding helicase activity ATP binding nucleus nucleolus chromatin modification hydrolase activity NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation
1553426_at	0.251	3.946	2.158	4.734e-02	0.384	-4.065	FLJ37543	hypothetical protein FLJ37543	5	60969392	NM_173667	285668	5q12.1	Hs.683866	2	extracellular region
203744_at	-0.626	6.139	-2.158	4.735e-02	0.384	-4.065	HMGB3	high-mobility group box 3	X	149902420	NM_005342	3149	Xq28	Hs.19114	11	nucleus chromosome multicellular organismal development DNA bending activity negative regulation of B cell differentiation negative regulation of myeloid cell differentiation
224416_s_at	-0.338	5.640	-2.157	4.735e-02	0.384	-4.065	MED28	mediator complex subunit 28	4	17225370	AF358829	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
1555281_x_at	-0.400	3.250	-2.157	4.737e-02	0.384	-4.066	ARMC8	armadillo repeat containing 8	3	139388837, 139388837	BC007934	25852	3q22.3	Hs.719108	4	binding
1562924_at	0.267	4.233	2.157	4.738e-02	0.384	-4.066	LOC340357	hypothetical LOC340357	8	-12667941	BC043360	340357	8p23.1	Hs.434302	1
217874_at	0.264	10.903	2.157	4.738e-02	0.384	-4.066	SUCLG1	succinate-CoA ligase, alpha subunit	2	-84504162	NM_003849	8802	2p11.2	Hs.270428	10	nucleotide binding ATP citrate synthase activity succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity GTP binding mitochondrion mitochondrial inner membrane mitochondrial matrix tricarboxylic acid cycle metabolic process ligase activity	Citrate cycle (TCA cycle) Propanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
205994_at	-0.297	4.077	-2.157	4.742e-02	0.384	-4.067	ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)	1	-203855018, -203851857	NM_001973	2005	1q32	Hs.497520 Hs.602654	21	transcription factor activity transcription cofactor activity protein binding nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding	MAPK signaling pathway
1557349_at	-0.174	3.585	-2.157	4.742e-02	0.384	-4.067	RERE	arginine-glutamic acid dipeptide (RE) repeats	1	-8335050, -8335050	AK096094	473	1p36.2-p36.1	Hs.463041	17	histone deacetylase complex transcription factor activity nucleus chromatin remodeling regulation of transcription, DNA-dependent NLS-bearing substrate import into nucleus multicellular organismal development poly-glutamine tract binding zinc ion binding sequence-specific DNA binding metal ion binding
228713_s_at	0.264	5.273	2.157	4.742e-02	0.384	-4.067	HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14	19	-54008085	AI742586	51171	19q13.33	Hs.18788	8	estradiol 17-beta-dehydrogenase activity protein binding cytoplasm cytosol lipid metabolic process steroid catabolic process oxidoreductase activity testosterone 17-beta-dehydrogenase (NADP+) activity oxidation reduction
201363_s_at	-0.586	6.360	-2.156	4.745e-02	0.384	-4.067	IVNS1ABP	influenza virus NS1A binding protein	1	-183532144	AB020657	10625	1q25.1-q31.1	Hs.497183	9	protein binding nucleus nucleoplasm transcription factor complex spliceosomal complex cytoplasm cytoskeleton transcription from RNA polymerase III promoter RNA splicing response to virus interspecies interaction between organisms
242512_at	-0.452	5.363	-2.156	4.745e-02	0.384	-4.067	MYO9A	myosin IXA	15	-69905414	AI382029	4649	15q22-q23	Hs.546268	8	nucleotide binding motor activity actin binding GTPase activator activity protein binding ATP binding intracellular intracellular signaling cascade visual perception zinc ion binding membrane integral to membrane myosin complex diacylglycerol binding metal ion binding
237378_at	0.225	5.706	2.156	4.746e-02	0.384	-4.067	FLJ46321	FAM75-like protein FLJ46321	9	83793506	AL040781	389763	9q21.32	Hs.209545		membrane integral to membrane
202143_s_at	-0.328	9.678	-2.156	4.748e-02	0.384	-4.068	COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	2	237658822	NM_006710	10920	2q37.3	Hs.531713	23	nucleus cytoplasm signalosome
202536_at	-0.467	7.541	-2.156	4.749e-02	0.384	-4.068	CHMP2B	chromatin modifying protein 2B	3	87359102	AK002165	25978	3p11.2	Hs.476930	36	intracellular cytoplasm endosome cytosol protein transport membrane protein domain specific binding	Endocytosis
223915_at	0.473	5.052	2.156	4.752e-02	0.384	-4.068	BCOR	BCL6 co-repressor	X	-39795442, -39795442	AF317392	54880	Xp21.2-p11.4	Hs.659681	19	transcription corepressor activity transcription corepressor activity ubiquitin-protein ligase activity nucleus heart development transcription factor binding chromatin modification heat shock protein binding PcG protein complex odontogenesis histone deacetylase binding negative regulation of transcription, DNA-dependent palate development specification of axis polarity
228628_at	0.336	6.516	2.156	4.752e-02	0.384	-4.068	SRGAP2P1	SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1	1		AI478268	653464	1p11.2	Hs.523529 Hs.698027	2
200607_s_at	-0.389	6.981	-2.156	4.752e-02	0.384	-4.068	RAD21	RAD21 homolog (S. pombe)	8	-117927354	BG289967	5885	8q24	Hs.81848	33	nuclear chromosome protein binding nucleus double-strand break repair apoptosis response to DNA damage stimulus cell cycle chromosome segregation mitosis reciprocal meiotic recombination cell division	Cell cycle
232245_at	1.167	8.406	2.155	4.754e-02	0.384	-4.069	SLC25A34	solute carrier family 25, member 34	1	15935395	AU151211	284723	1p36.21	Hs.631867	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
201885_s_at	-0.348	10.193	-2.155	4.758e-02	0.384	-4.070	CYB5R3	cytochrome b5 reductase 3	22	-41344757, -41344757	NM_000398	1727	22q13.2-q13.31 22q13.31-qter	Hs.700572	49	cytochrome-b5 reductase activity cytoplasm mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane hemoglobin complex cholesterol biosynthetic process blood circulation electron carrier activity membrane oxidoreductase activity oxidation reduction	Amino sugar and nucleotide sugar metabolism
203683_s_at	0.374	6.853	2.155	4.759e-02	0.384	-4.070	VEGFB	vascular endothelial growth factor B	11	63758841	NM_003377	7423	11q13	Hs.78781	23	regulation of cell growth vascular endothelial growth factor receptor binding protein binding extracellular region extracellular region signal transduction growth factor activity heparin binding positive regulation of cell proliferation membrane platelet alpha granule lumen	Cytokine-cytokine receptor interaction mTOR signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer
209970_x_at	0.303	5.261	2.155	4.761e-02	0.384	-4.070	CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	11	-104401446	M87507	834	11q23	Hs.2490	134	cysteine-type endopeptidase activity protein binding intracellular cytoplasm proteolysis signal transduction peptidase activity caspase activator activity regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade	Amyotrophic lateral sclerosis (ALS)
217112_at	0.196	4.100	2.155	4.761e-02	0.384	-4.070	PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	22	-37949632, -37949632	Z81010	5155	22q12.3-q13.1 22q13.1	Hs.1976	140	response to hypoxia positive regulation of endothelial cell proliferation monocyte chemotaxis platelet-derived growth factor receptor binding collagen binding extracellular region extracellular region cytoplasm substrate-bound cell migration transforming growth factor beta receptor signaling pathway growth factor activity response to wounding cell surface negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation positive regulation of smooth muscle cell migration membrane cell growth cell projection assembly actin cytoskeleton organization negative regulation of cell migration platelet dense granule lumen protein homodimerization activity positive regulation of MAP kinase activity cell surface binding positive regulation of blood vessel endothelial cell migration positive regulation of DNA replication protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding regulation of peptidyl-tyrosine phosphorylation positive regulation of chemotaxis cell chemotaxis	MAPK signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Renal cell carcinoma Glioma Prostate cancer Melanoma
211062_s_at	0.188	6.147	2.154	4.763e-02	0.384	-4.070	CPZ	carboxypeptidase Z	4	8645334	BC006393	8532	4p16.1	Hs.78068	8	metallocarboxypeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity metallopeptidase activity zinc ion binding Wnt receptor signaling pathway metal ion binding
225225_at	-0.252	10.855	-2.154	4.763e-02	0.384	-4.070	LOC729082	hypothetical protein LOC729082	15	39363492	BF791544	729082	15q15.1	Hs.380164	2
223608_at	0.550	6.228	2.154	4.763e-02	0.384	-4.070	EFCAB2	EF-hand calcium binding domain 2	1	243199793, 243199906, 243200253, 243200253	BC005357	84288	1q44	Hs.134857	5	calcium ion binding
212622_at	-0.385	7.450	-2.154	4.764e-02	0.384	-4.071	TMEM41B	transmembrane protein 41B	11	-9258777	N64760	440026	11p15.4	Hs.594563	4	membrane integral to membrane
223072_s_at	0.244	7.061	2.154	4.765e-02	0.384	-4.071	WBP1	WW domain binding protein 1	2	74539084	U79457	23559	2p12	Hs.516114	9	protein binding protein binding biological_process integral to membrane WW domain binding WW domain binding
230038_at	0.387	4.932	2.154	4.768e-02	0.384	-4.071	ATXN7L2	ataxin 7-like 2	1	109828083	N93313	127002	1p13.3	Hs.118248	2
209718_at	0.225	5.870	2.154	4.768e-02	0.384	-4.071	NCAPH2	non-SMC condensin II complex, subunit H2	22	49293510, 49293510	BC001298	29781	22q13.33	Hs.180903	5	nucleus chromosome condensation
236146_at	-0.332	4.327	-2.154	4.769e-02	0.384	-4.072	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	BF593158	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
209249_s_at	-0.278	11.307	-2.154	4.770e-02	0.384	-4.072	GHITM	growth hormone inducible transmembrane protein	10	85889164	AF131820	27069	10q23.1	Hs.352656	15	molecular_function biological_process membrane integral to membrane
224822_at	0.289	6.747	2.154	4.771e-02	0.384	-4.072	DLC1	deleted in liver cancer 1	8	-13116452, -12985242, -12985242	AA524250	10395	8p22	Hs.134296	48	neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation
233403_x_at	0.272	5.279	2.153	4.773e-02	0.384	-4.072	TM6SF2	transmembrane 6 superfamily member 2	19	-19236173	AK026307	53345	19p13.3-p12	Hs.531624	6	molecular_function biological_process membrane integral to membrane
216217_at	0.294	5.384	2.153	4.774e-02	0.384	-4.072	PLCL2	phospholipase C-like 2	3	16901455, 16949585	AK023546	23228	3p24.3	Hs.202010	7	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
207851_s_at	-0.311	4.924	-2.153	4.775e-02	0.384	-4.073	INSR	insulin receptor	19	-7063265	NM_000208	3643	19p13.3-p13.2	Hs.465744	351	nucleotide binding activation of MAPK activity positive regulation of protein amino acid phosphorylation heart morphogenesis receptor signaling protein tyrosine kinase activity receptor activity insulin receptor activity insulin-like growth factor receptor binding ATP binding GTP binding endosome microsome cytosol plasma membrane plasma membrane insulin receptor complex caveola carbohydrate metabolic process G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation positive regulation of cell proliferation insulin receptor signaling pathway endosome membrane transferase activity peptidyl-tyrosine phosphorylation transformation of host cell by virus protein phosphatase binding male sex determination positive regulation of cell migration insulin-like growth factor I binding insulin-like growth factor II binding activation of protein kinase B activity regulation of gene-specific transcription SH2 domain binding glucose homeostasis positive regulation of MAPKKK cascade 3-phosphoinositide-dependent protein kinase binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of nitric oxide biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of DNA replication positive regulation of glycolysis positive regulation of mitosis regulation of embryonic development positive regulation of glucose import positive regulation of glucose import protein amino acid autophosphorylation positive regulation of developmental growth protein heterotetramerization PTB domain binding positive regulation of protein kinase B signaling cascade positive regulation of respiratory burst	Adherens junction Insulin signaling pathway Type II diabetes mellitus
202738_s_at	-0.601	8.619	-2.153	4.777e-02	0.384	-4.073	PHKB	phosphorylase kinase, beta	16	46052710	BG149218	5257	16q12-q13	Hs.78060	13	catalytic activity calmodulin binding plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy	Calcium signaling pathway Insulin signaling pathway
228931_at	-0.390	6.277	-2.153	4.778e-02	0.384	-4.073	COQ4	coenzyme Q4 homolog (S. cerevisiae)	9	130124611	AW628685	51117	9q34.11	Hs.98541	9	mitochondrion ubiquinone biosynthetic process
207303_at	0.218	3.652	2.153	4.780e-02	0.384	-4.074	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	7	-31795771	NM_005020	5137	7p14.3	Hs.655694	10	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity	Purine metabolism Calcium signaling pathway Olfactory transduction
205874_at	0.312	5.142	2.153	4.780e-02	0.384	-4.074	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A	15	39573413	NM_002220	3706	15q14-q21	Hs.2722	18	nucleotide binding calmodulin binding ATP binding inositol metabolic process signal transduction inositol trisphosphate 3-kinase activity kinase activity transferase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system
204281_at	-0.273	8.533	-2.152	4.781e-02	0.384	-4.074	TEAD4	TEA domain family member 4	12	2938756, 2939222	NM_003213	7004	12p13.3-p13.2	Hs.94865	16	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter muscle organ development
1563796_s_at	-0.437	5.161	-2.152	4.781e-02	0.384	-4.074	EARS2	glutamyl-tRNA synthetase 2, mitochondrial (putative)	16	-23440834	AK095998	124454	16p12.2	Hs.620541	6	nucleotide binding RNA binding glutamate-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix glutamyl-tRNA aminoacylation ligase activity	Porphyrin and chlorophyll metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways
201852_x_at	-1.008	7.589	-2.152	4.782e-02	0.384	-4.074	COL3A1	collagen, type III, alpha 1	2	189547343	AI813758	1281	2q31	Hs.443625 Hs.708235	130	integrin binding integrin binding extracellular matrix structural constituent protein binding extracellular region collagen collagen type III collagen type III extracellular space extracellular space cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway heart development response to radiation peptide cross-linking platelet activation collagen fibril organization collagen fibril organization collagen biosynthetic process collagen biosynthetic process response to cytokine stimulus wound healing wound healing fibril organization skin development platelet-derived growth factor binding negative regulation of immune response	Focal adhesion ECM-receptor interaction
235315_at	-0.314	4.044	-2.152	4.782e-02	0.384	-4.074	TSC22D1	TSC22 domain family, member 1	13	-43905658, -43905654	AI809519	8848	13q14	Hs.507916	23	transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter
231880_at	-0.434	8.152	-2.152	4.784e-02	0.384	-4.074	FAM40B	family with sequence similarity 40, member B	7	128861509, 128861509	AB032996	57464	7q32.1	Hs.489988	9	molecular_function cellular_component biological_process
230914_at	0.290	4.040	2.152	4.784e-02	0.384	-4.074	HNF4A	hepatocyte nuclear factor 4, alpha	20	42417854, 42417854, 42463337, 42463337	AI032108	3172	20q12-q13.1	Hs.116462	217	transcription factor activity steroid hormone receptor activity receptor binding steroid binding fatty acid binding nucleus cytoplasm regulation of transcription, DNA-dependent ornithine metabolic process xenobiotic metabolic process blood coagulation zinc ion binding negative regulation of cell proliferation positive regulation of specific transcription from RNA polymerase II promoter regulation of lipid metabolic process negative regulation of cell growth protein homodimerization activity sequence-specific DNA binding metal ion binding lipid homeostasis	Maturity onset diabetes of the young
207245_at	0.222	2.163	2.151	4.790e-02	0.385	-4.075	UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	4	-69085497	NM_001077	7367	4q13	Hs.575083	29	membrane fraction endoplasmic reticulum microsome metabolic process steroid metabolic process glucuronosyltransferase activity membrane integral to membrane	Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Androgen and estrogen metabolism Starch and sucrose metabolism Retinol metabolism Porphyrin and chlorophyll metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
222099_s_at	-0.288	7.078	-2.151	4.792e-02	0.385	-4.076	LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)	19	39355191	AW593859	26065	19q13.11	Hs.718430	6
206635_at	0.236	6.983	2.151	4.793e-02	0.385	-4.076	CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	1	152806880	NM_000748	1141	1q21.3	Hs.2306	59	conditioned taste aversion response to hypoxia nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport calcium ion transport smooth muscle contraction signal transduction synaptic transmission, cholinergic visual perception sensory perception of sound memory locomotory behavior visual learning external side of plasma membrane acetylcholine receptor activity integral to membrane sensory perception of pain vestibulocochlear nerve development optic nerve morphogenesis lateral geniculate nucleus development central nervous system projection neuron axonogenesis cell junction positive regulation of B cell proliferation positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion behavioral response to nicotine social behavior regulation of dopamine metabolic process B cell activation response to cocaine regulation of circadian sleep/wake cycle, REM sleep regulation of circadian sleep/wake cycle, non-REM sleep synapse postsynaptic membrane response to ethanol negative regulation of action potential regulation of dendrite morphogenesis cognition membrane depolarization regulation of synaptogenesis synaptic transmission involved in micturition
202083_s_at	-0.436	5.899	-2.151	4.794e-02	0.385	-4.076	SEC14L1	SEC14-like 1 (S. cerevisiae)	17	72648599, 72692889	AI017770	6397	17q25.1-q25.2	Hs.464184	11	binding Golgi apparatus membrane
203740_at	0.392	7.753	2.151	4.795e-02	0.385	-4.076	MPHOSPH6	M-phase phosphoprotein 6	16	-80739267	NM_005792	10200	16q23.3	Hs.344400	11	M phase of mitotic cell cycle protein binding nucleus nucleolus cytoplasm	RNA degradation
218845_at	-0.275	8.105	-2.151	4.795e-02	0.385	-4.076	DUSP22	dual specificity phosphatase 22	6	237100	NM_020185	56940	6p25.3	Hs.29106	13	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation apoptosis transforming growth factor beta receptor signaling pathway multicellular organismal development protein tyrosine/serine/threonine phosphatase activity hydrolase activity regulation of cell proliferation positive regulation of JNK cascade
216651_s_at	0.238	3.650	2.150	4.801e-02	0.385	-4.077	GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	10	26545241, 26545241	X69936	2572	10p11.23	Hs.231829	62	glutamate decarboxylase activity protein binding cytoplasm Golgi apparatus cytosol plasma membrane glutamate decarboxylation to succinate synaptic transmission lyase activity carboxylic acid metabolic process cell junction pyridoxal phosphate binding cytoplasmic vesicle neurotransmitter biosynthetic process synapse	Alanine, aspartate and glutamate metabolism beta-Alanine metabolism Taurine and hypotaurine metabolism Butanoate metabolism Metabolic pathways Type I diabetes mellitus
219884_at	0.311	5.923	2.150	4.802e-02	0.385	-4.077	LHX6	LIM homeobox 6	9	-124004678	NM_014368	26468	9q33.2	Hs.103137	11	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding cerebral cortex radially oriented cell migration cerebral cortex tangential migration cerebral cortex GABAergic interneuron migration sequence-specific DNA binding metal ion binding cell maturation
1569269_s_at	0.250	3.816	2.150	4.802e-02	0.385	-4.077	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	12	62524807	BM912471	57522	12q14.2	Hs.210751 Hs.593803	8	GTPase activator activity intracellular signal transduction	Axon guidance
206076_at	-0.330	5.596	-2.150	4.803e-02	0.385	-4.078	LRRC23	leucine rich repeat containing 23	12	6884157	NM_006992	10233	12p13	Hs.155586	10	molecular_function protein binding cellular_component biological_process
233918_at	0.192	5.921	2.150	4.804e-02	0.385	-4.078	DCDC2B	doublecortin domain containing 2B	1	32447281	AI924786	149069	1p35.1	Hs.424588	1	intracellular signaling cascade
226157_at	-0.407	7.296	-2.150	4.806e-02	0.385	-4.078	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	AI569747	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
241198_s_at	0.190	2.629	2.150	4.806e-02	0.385	-4.078	C11orf70	chromosome 11 open reading frame 70	11	101423408	BE645435	85016	11q22.1	Hs.98328	3
222118_at	-0.333	3.093	-2.150	4.808e-02	0.385	-4.078	CENPN	centromere protein N	16	79597603, 79597603, 79597603	AK023669	55839	16q23.2	Hs.55028	9	chromosome, centromeric region condensed chromosome kinetochore nucleus chromosome
221558_s_at	0.330	3.979	2.149	4.808e-02	0.385	-4.079	LEF1	lymphoid enhancer-binding factor 1	4	-109188149	AF288571	51176	4q23-q25	Hs.719332	85	negative regulation of transcription from RNA polymerase II promoter somitogenesis epithelial to mesenchymal transition placenta development chromatin binding RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex nucleolus cytoplasm DNA bending activity transcription activator activity dentate gyrus development regulation of Wnt receptor signaling pathway embryonic limb morphogenesis mammary gland development odontogenesis of dentine-containing tooth sequence-specific DNA binding regulation of transcription negative regulation of striated muscle development positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm formation cell development palate development	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
229776_at	0.256	5.650	2.149	4.808e-02	0.385	-4.079	SLCO3A1	solute carrier organic anion transporter family, member 3A1	15	90197941, 90197941	AW138118	28232	15q26	Hs.311187	10	transporter activity ion transport membrane integral to membrane
1555923_a_at	0.205	3.904	2.149	4.810e-02	0.385	-4.079	C10orf114	chromosome 10 open reading frame 114	10	-21823426	BQ007522	399726	10p12.31	Hs.315568	3
223726_at	0.210	6.530	2.149	4.810e-02	0.385	-4.079	KCNH3	potassium voltage-gated channel, subfamily H (eag-related), member 3	12	48219206	AB022696	23416	12q13	Hs.64064	4	two-component sensor activity two-component signal transduction system (phosphorelay) voltage-gated ion channel activity voltage-gated potassium channel activity regulation of transcription, DNA-dependent ion transport potassium ion transport membrane integral to membrane potassium ion binding
1568629_s_at	0.270	7.774	2.149	4.811e-02	0.385	-4.079	PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	19	18125015	BC033311	5296	19q13.2-q13.4	Hs.371344	68	protein binding intracellular cytosol phosphoinositide 3-kinase complex signal transduction 1-phosphatidylinositol-3-kinase activity negative regulation of anti-apoptosis phosphoinositide 3-kinase regulator activity	ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
203925_at	-0.772	7.373	-2.149	4.812e-02	0.385	-4.079	GCLM	glutamate-cysteine ligase, modifier subunit	1	-94125177	NM_002061	2730	1p22.1	Hs.315562	40	glutamate-cysteine ligase activity glutamate-cysteine ligase activity protein binding soluble fraction cytosol cysteine metabolic process glutamate metabolic process glutathione biosynthetic process glutathione biosynthetic process response to oxidative stress oxidoreductase activity glutamate-cysteine ligase complex glutamate-cysteine ligase catalytic subunit binding positive regulation of glutamate-cysteine ligase activity response to drug negative regulation of neuron apoptosis protein heterodimerization activity regulation of blood vessel size response to nitrosative stress regulation of mitochondrial depolarization oxidation reduction	Glutathione metabolism Metabolic pathways
205061_s_at	0.297	7.259	2.149	4.814e-02	0.385	-4.080	EXOSC9	exosome component 9	4	122941921	NM_005033	5393	4q27	Hs.91728	17	3'-5'-exoribonuclease activity nuclear exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing immune response hydrolase activity	RNA degradation
201524_x_at	-0.224	9.600	-2.149	4.815e-02	0.385	-4.080	UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	12	-92326218	NM_003348	7334	12q22	Hs.524630	37	nucleotide binding double-strand break repair via homologous recombination DNA double-strand break processing ubiquitin-protein ligase activity protein binding ATP binding nucleus cytoplasm postreplication repair proteolysis response to DNA damage stimulus ligase activity modification-dependent protein catabolic process positive regulation of histone modification UBC13-MMS2 complex regulation of histone ubiquitination positive regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding positive regulation of DNA repair T cell receptor signaling pathway positive regulation of NF-kappaB transcription factor activity regulation of protein metabolic process positive regulation of ubiquitin-protein ligase activity	Ubiquitin mediated proteolysis
205222_at	0.918	4.020	2.149	4.816e-02	0.385	-4.080	EHHADH	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	3	-186391105	NM_001966	1962	3q26.3-q28	Hs.429879	9	3-hydroxyacyl-CoA dehydrogenase activity dodecenoyl-CoA delta-isomerase activity enoyl-CoA hydratase activity binding mitochondrion peroxisome lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity lyase activity isomerase activity coenzyme binding oxidation reduction	Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Metabolic pathways PPAR signaling pathway
225974_at	-0.881	6.270	-2.148	4.817e-02	0.385	-4.080	TMEM64	transmembrane protein 64	8	-91703398	BF732480	169200	8q21.3	Hs.567759	2	membrane integral to membrane
208209_s_at	0.259	4.459	2.148	4.818e-02	0.385	-4.080	C4BPB	complement component 4 binding protein, beta	1	205328834, 205329206, 205329250	NM_000716	725	1q32	Hs.99886	23	extracellular region complement activation, classical pathway blood coagulation innate immune response	Complement and coagulation cascades
223176_at	-0.448	5.931	-2.148	4.819e-02	0.385	-4.080	KCTD20	potassium channel tetramerisation domain containing 20	6	36518521	BC003697	222658	6p21.31	Hs.188757	4	voltage-gated potassium channel activity potassium ion transport voltage-gated potassium channel complex membrane identical protein binding
204744_s_at	0.465	9.932	2.148	4.822e-02	0.385	-4.081	IARS	isoleucyl-tRNA synthetase	9	-94012445, -94012445	NM_013417	3376	9q21	Hs.445403	13	nucleotide binding isoleucine-tRNA ligase activity ATP binding soluble fraction cytoplasm isoleucyl-tRNA aminoacylation zinc ion binding ligase activity	Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis
223495_at	0.399	4.972	2.148	4.822e-02	0.385	-4.081	CCDC8	coiled-coil domain containing 8	19	-51605426	AI970823	83987	19q13.32	Hs.97876	4	plasma membrane
235774_at	0.277	3.858	2.148	4.823e-02	0.385	-4.081	LOC553137	hypothetical LOC553137	6	-107324697	AV699047	553137	6q21	Hs.597380 Hs.652438	1
208147_s_at	0.285	2.458	2.147	4.827e-02	0.386	-4.082	CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	10	-96786518	NM_030878	1558	10q23.33	Hs.709188	97	monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	Arachidonic acid metabolism Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
205284_at	-0.320	6.224	-2.147	4.827e-02	0.386	-4.082	URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	1	227828603	NM_014777	9816	1q42.13	Hs.533628	5	nucleus nucleolus
208917_x_at	0.285	5.273	2.147	4.828e-02	0.386	-4.082	NADK	NAD kinase	1	-1672530	BE674658	65220	1p36.33-p36.21	Hs.654792	12	nucleotide binding NAD+ kinase activity NAD+ kinase activity protein binding ATP binding cytosol cytosol metabolic process phosphorylation transferase activity NAD metabolic process ATP metabolic process metal ion binding	Nicotinate and nicotinamide metabolism Metabolic pathways
1558573_at	0.327	3.337	2.147	4.833e-02	0.386	-4.083	MCTS1	malignant T cell amplified sequence 1	X	119621771, 119622579	AF456465	28985	Xq22-q24	Hs.102696 Hs.670803	12	RNA binding cytoplasm response to DNA damage stimulus cell cycle positive regulation of cell proliferation regulation of growth regulation of transcription
215726_s_at	0.386	7.190	2.146	4.839e-02	0.386	-4.084	CYB5A	cytochrome b5 type A (microsomal)	18	-70071506	M22976	1528	18q23	Hs.465413	38	aldo-keto reductase activity cytochrome-c oxidase activity cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum microsome transport membrane integral to membrane heme binding electron transport chain metal ion binding
210501_x_at	0.285	11.175	2.146	4.842e-02	0.386	-4.085	EIF3K	eukaryotic translation initiation factor 3, subunit K	19	43801561	AF119846	27335	19q13.2	Hs.314359	15	translation initiation factor activity translation initiation factor activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex regulation of translational initiation ribosome binding
222128_at	0.353	4.525	2.145	4.846e-02	0.387	-4.085	NSUN6	NOL1/NOP2/Sun domain family, member 6	10	-18874269	U80764	221078	10p12.31	Hs.396175	4	RNA binding methyltransferase activity transferase activity
213603_s_at	0.361	5.445	2.145	4.847e-02	0.387	-4.086	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	22	-35951255	BE138888	5880	22q13.1	Hs.517601	58	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction nuclear envelope cytoplasm chemotaxis signal transduction small GTPase mediated signal transduction positive regulation of cell proliferation regulation of hydrogen peroxide metabolic process cell projection assembly actin cytoskeleton organization regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Pancreatic cancer
241812_at	-0.346	5.277	-2.145	4.847e-02	0.387	-4.086	SPATS2L	spermatogenesis associated, serine-rich 2-like	2	200878848, 200879229, 200879600	AV648669	26010	2q33.1	Hs.120323	9
240072_at	0.325	3.737	2.145	4.848e-02	0.387	-4.086	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	N75937	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
218760_at	-0.358	7.637	-2.145	4.848e-02	0.387	-4.086	COQ6	coenzyme Q6 homolog, monooxygenase (S. cerevisiae)	14	73486395, 73486708	NM_015940	51004	14q24.3	Hs.632335	7	mitochondrion ubiquinone biosynthetic process oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen FAD binding oxidation reduction	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
1558034_s_at	0.291	2.954	2.145	4.850e-02	0.387	-4.086	CP	ceruloplasmin (ferroxidase)	3	-150372979	AL556703	1356	3q23-q25	Hs.558314	95	ferroxidase activity copper ion binding extracellular region extracellular space ion transport copper ion transport cellular iron ion homeostasis aging response to nutrient oxidoreductase activity anchored to plasma membrane metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
201593_s_at	-0.384	8.638	-2.145	4.850e-02	0.387	-4.086	ZC3H15	zinc finger CCCH-type containing 15	2	187059129	AV716798	55854	2q32.1	Hs.368598	3	nucleic acid binding nucleus cytoplasm zinc ion binding cytokine-mediated signaling pathway metal ion binding
1557953_at	-0.289	6.391	-2.145	4.852e-02	0.387	-4.086	ZKSCAN1	zinc finger with KRAB and SCAN domains 1	7	99451154	BG761185	7586	7q21.3-q22.1	Hs.615360	11	transcription factor activity intracellular nucleus cytoplasm mitochondrion regulation of transcription, DNA-dependent zinc ion binding metal ion binding
217863_at	-0.410	6.856	-2.145	4.852e-02	0.387	-4.086	PIAS1	protein inhibitor of activated STAT, 1	15	66133625	AI348378	8554	15q	Hs.162458	67	DNA binding transcription coactivator activity transcription corepressor activity nucleus JAK-STAT cascade zinc ion binding nuclear speck SUMO ligase activity enzyme binding modification-dependent protein catabolic process androgen receptor signaling pathway positive regulation of protein sumoylation regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding	Ubiquitin mediated proteolysis Jak-STAT signaling pathway Pathways in cancer Small cell lung cancer
205594_at	-0.558	6.699	-2.145	4.852e-02	0.387	-4.086	ZNF652	zinc finger protein 652	17	-44721567, -44721567	NM_014897	22834	17q21.32-q21.33	Hs.463375	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
218669_at	-0.346	7.493	-2.144	4.857e-02	0.387	-4.087	RAP2C	RAP2C, member of RAS oncogene family	X	-131164733	NM_021183	57826	Xq25	Hs.119889	5	nucleotide binding GTP binding intracellular plasma membrane small GTPase mediated signal transduction
212595_s_at	-0.428	7.282	-2.144	4.859e-02	0.387	-4.088	DAZAP2	DAZ associated protein 2	12	49918774, 49918774	AL534321	9802	12q12	Hs.369761	15	protein binding WW domain binding
201629_s_at	-0.292	7.905	-2.144	4.859e-02	0.387	-4.088	ACP1	acid phosphatase 1, soluble	2	254868, 254868	BE872974	52	2p25	Hs.558296	69	acid phosphatase activity non-membrane spanning protein tyrosine phosphatase activity soluble fraction cytoplasm protein amino acid dephosphorylation hydrolase activity identical protein binding	gamma-Hexachlorocyclohexane degradation Riboflavin metabolism Adherens junction
212447_at	-0.413	8.214	-2.144	4.859e-02	0.387	-4.088	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	7	-32874302	AF161402	25948	7p14.3	Hs.372541	4	protein binding
224599_at	-0.432	8.419	-2.144	4.859e-02	0.387	-4.088	CGGBP1	CGG triplet repeat binding protein 1	3	-88183789	BF979809	8545	3p12-p11.1	Hs.444818	14	DNA binding double-stranded DNA binding nucleus regulation of transcription
225579_at	-0.393	6.230	-2.144	4.861e-02	0.387	-4.088	PQLC3	PQ loop repeat containing 3	2	11212990	AL516202	130814	2p25.1	Hs.274415	5	membrane integral to membrane
207950_s_at	-0.541	5.136	-2.144	4.862e-02	0.387	-4.088	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10	-61458164, -61458164	NM_001149	288	10q21	Hs.499725	30	protein binding cytoplasm cytoskeleton signal transduction basolateral plasma membrane establishment of protein localization
204870_s_at	0.295	3.579	2.144	4.862e-02	0.387	-4.088	PCSK2	proprotein convertase subtilisin/kexin type 2	20	17155630	NM_002594	5126	20p11.2	Hs.315186	34	serine-type endopeptidase activity protein binding extracellular space soluble fraction proteolysis nervous system development peptidase activity membrane protein autoprocessing insulin processing secretory granule cytoplasmic vesicle enkephalin processing islet amyloid polypeptide processing
211045_s_at	0.307	4.397	2.143	4.864e-02	0.387	-4.089	KCNH6	potassium voltage-gated channel, subfamily H (eag-related), member 6	17	58954426, 58954426	BC006334	81033	17q23.3	Hs.591177	6	voltage-gated ion channel activity voltage-gated potassium channel activity regulation of transcription, DNA-dependent ion transport potassium ion transport signal transduction membrane integral to membrane potassium ion binding
1560834_a_at	0.209	4.971	2.143	4.864e-02	0.387	-4.089	RMST	rhabdomyosarcoma 2 associated transcript (non-protein coding)	12	96382929	AF429305	196475	12q21 12q23.1	Hs.652568	2
225408_at	0.207	5.655	2.143	4.864e-02	0.387	-4.089	MBP	myelin basic protein	18	-72853726, -72819776, -72819776	N21191	4155	18q23	Hs.551713	102	plasma membrane immune response synaptic transmission central nervous system development structural constituent of myelin sheath internode region of axon myelination cell projection cell soma myelin sheath
46665_at	0.350	6.653	2.143	4.866e-02	0.387	-4.089	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C	2	-96889199	AI949392	54910	2q11.2	Hs.516220	9	receptor activity protein binding multicellular organismal development nervous system development membrane integral to membrane cell differentiation	Axon guidance
40446_at	-0.207	8.792	-2.143	4.867e-02	0.387	-4.089	PHF1	PHD finger protein 1	6	33486750	AL021366	5252	6p21.3	Hs.166204	15	nucleic acid binding transcription factor activity protein binding nucleus zinc ion binding chromatin modification regulation of transcription metal ion binding
244802_at	0.251	3.285	2.143	4.868e-02	0.387	-4.089	GLUD1	glutamate dehydrogenase 1	10	-88800222	AA909218	2746	10q23.3	Hs.500409	53	nucleotide binding glutamate dehydrogenase activity glutamate dehydrogenase [NAD(P)+] activity glutamate dehydrogenase [NAD(P)+] activity ATP binding GTP binding cytoplasm mitochondrion mitochondrial matrix mitochondrial matrix cellular amino acid metabolic process glutamate biosynthetic process oxidoreductase activity glutamate deamidation positive regulation of insulin secretion identical protein binding ADP binding oxidation reduction NAD binding leucine binding	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism D-Glutamine and D-glutamate metabolism Nitrogen metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
205759_s_at	0.308	4.742	2.143	4.868e-02	0.387	-4.089	SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	19	53747240, 53770804	NM_004605	6820	19q13.3	Hs.369331	29	alcohol sulfotransferase activity protein binding cytoplasm cytosol lipid metabolic process steroid metabolic process transferase activity steroid sulfotransferase activity	Androgen and estrogen metabolism Sulfur metabolism
212326_at	-0.300	7.094	-2.143	4.870e-02	0.387	-4.090	VPS13D	vacuolar protein sorting 13 homolog D (S. cerevisiae)	1	12212699	AB007922	55187	1p36.22	Hs.439381	9	protein localization
38691_s_at	0.183	6.446	2.143	4.871e-02	0.387	-4.090	SFTPC	surfactant protein C	8	22075128	J03553	6440	8p21	Hs.1074	68	extracellular region extracellular space respiratory gaseous exchange regulation of liquid surface tension
218397_at	0.355	6.817	2.143	4.871e-02	0.387	-4.090	FANCL	Fanconi anemia, complementation group L	2	-58239881	NM_018062	55120	2p16.1	Hs.631890	19	protein binding nucleus cytoplasm DNA repair response to DNA damage stimulus zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
231306_at	0.192	4.929	2.143	4.871e-02	0.387	-4.090	LYZL4	lysozyme-like 4	3	-42413578	AI989932	131375	3p22.1	Hs.234895	3	lysozyme activity extracellular region cell wall macromolecule catabolic process
207998_s_at	0.263	4.853	2.142	4.875e-02	0.387	-4.091	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit	3	53504070	NM_000720	776	3p14.3	Hs.476358	25	voltage-gated ion channel activity calcium ion binding voltage-gated calcium channel complex ion transport calcium ion transport dihydropyridine-sensitive calcium channel activity membrane integral to membrane	MAPK signaling pathway Calcium signaling pathway Cardiac muscle contraction Vascular smooth muscle contraction GnRH signaling pathway Type II diabetes mellitus Alzheimer's disease Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
214339_s_at	0.297	5.609	2.142	4.877e-02	0.387	-4.091	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	19	-43770120	AA744529	11184	19q13.1-q13.4	Hs.95424	29	nucleotide binding activation of MAPKKK activity protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding response to stress protein kinase cascade activation of JUN kinase activity MAP kinase kinase kinase kinase activity transferase activity peptidyl-serine phosphorylation	MAPK signaling pathway
203164_at	-0.406	5.103	-2.142	4.878e-02	0.387	-4.091	SLC33A1	solute carrier family 33 (acetyl-CoA transporter), member 1	3	-157028064	BE464756	9197	3q25.31	Hs.478031	5	membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane transport cell death acetyl-CoA transporter activity membrane	Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
1555787_at	0.227	4.156	2.142	4.878e-02	0.387	-4.091	C11orf63	chromosome 11 open reading frame 63	11	122258682, 122258682	BC009820	79864	11q24.1	Hs.164705	3
1555632_at	0.248	5.192	2.142	4.880e-02	0.387	-4.091	PIK3IP1	phosphoinositide-3-kinase interacting protein 1	22	-30007579	AF528079	113791	22q12.2	Hs.26670	11	membrane integral to membrane
206510_at	-0.676	6.218	-2.141	4.883e-02	0.387	-4.092	SIX2	SIX homeobox 2	2	-45085828	AF332197	10736	2p16-p15	Hs.101937	10	metanephros development transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent protein import into nucleus multicellular organismal development middle ear morphogenesis sequence-specific DNA binding negative regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
204421_s_at	0.391	4.871	2.141	4.886e-02	0.387	-4.092	FGF2	fibroblast growth factor 2 (basic)	4	123967312	M27968	2247	4q26-q27	Hs.284244	320	activation of MAPKK activity activation of MAPK activity induction of an organ positive regulation of protein amino acid phosphorylation protein binding extracellular region extracellular region extracellular space apoptosis chemotaxis signal transduction Ras protein signal transduction multicellular organismal development nervous system development growth factor activity heparin binding negative regulation of cell proliferation fibroblast growth factor receptor signaling pathway organ morphogenesis glial cell differentiation positive regulation of granule cell precursor proliferation lung development positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration positive regulation of cell differentiation positive regulation of angiogenesis regulation of retinal cell programmed cell death positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
1561589_a_at	-0.279	2.975	-2.141	4.886e-02	0.387	-4.092	NBEAL1	neurobeachin-like 1	2	203587846, 203708717	AB053319	65065	2q33.2	Hs.604686 Hs.648846	6
1554765_a_at	0.222	2.878	2.141	4.887e-02	0.387	-4.093	C11orf64	chromosome 11 open reading frame 64	11	60139799	BC029583	283197	11q12.2	Hs.372650	2	membrane integral to membrane
1554250_s_at	0.382	4.744	2.141	4.887e-02	0.387	-4.093	TRIM73	tripartite motif-containing 73	7	74862838	BC033812	375593	7q11.23	Hs.632307 Hs.661254	5	protein binding intracellular zinc ion binding metal ion binding
216452_at	0.268	3.680	2.140	4.895e-02	0.388	-4.094	TRPM3	transient receptor potential cation channel, subfamily M, member 3	9	-72588597, -72339785, -72339785	AB046836	80036	9q21.12	Hs.47288	19	calcium channel activity calcium ion binding cation transport calcium ion transport membrane integral to membrane
1552889_a_at	0.283	7.034	2.140	4.895e-02	0.388	-4.094	EXOC3L2	exocyst complex component 3-like 2	19	-50407718	NM_138568	90332	19q13.32	Hs.337557	5
1554564_a_at	0.223	4.942	2.140	4.896e-02	0.388	-4.094	UNQ1887	signal peptide peptidase 3	12	-119685417	BC011943	121665	12q24.31	Hs.507087 Hs.683964	12	aspartic-type endopeptidase activity peptidase activity membrane integral to membrane
202533_s_at	-0.600	5.002	-2.140	4.900e-02	0.388	-4.095	DHFR	dihydrofolate reductase	5	-79957800	BC003584	1719	5q11.2-q13.2	Hs.592364 Hs.648635	80	dihydrofolate reductase activity cellular_component glycine biosynthetic process one-carbon metabolic process nucleotide biosynthetic process oxidoreductase activity NADP or NADPH binding oxidation reduction	One carbon pool by folate Folate biosynthesis Biosynthesis of phenylpropanoids Metabolic pathways
209216_at	-0.370	8.568	-2.140	4.900e-02	0.388	-4.095	WDR45	WD repeat domain 45	X	-48819035, -48819035	BC000464	11152	Xp11.23	Hs.632807	8
207809_s_at	-0.259	7.198	-2.140	4.900e-02	0.388	-4.095	ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	X	153310171	NM_001183	537	Xq28	Hs.6551	22	nucleotide binding transporter activity ATP binding vacuole ion transport ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting two-sector ATPase complex proton-transporting V-type ATPase, V1 domain hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
226671_at	-0.527	7.116	-2.139	4.900e-02	0.388	-4.095	LAMP2	lysosomal-associated membrane protein 2	X	-119454376, -119444030	AI150000	3920	Xq24	Hs.496684	52	membrane fraction lysosomal membrane late endosome plasma membrane plasma membrane integral to membrane platelet dense granule membrane platelet dense granule membrane	Lysosome
223602_at	-0.306	4.856	-2.139	4.901e-02	0.388	-4.095	USP30	ubiquitin specific peptidase 30	12	107974762	BC004868	84749	12q24.11	Hs.486434 Hs.660996	7	ubiquitin thiolesterase activity mitochondrion mitochondrial outer membrane ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity membrane integral to membrane
232253_at	0.343	6.864	2.139	4.903e-02	0.388	-4.095	C5orf56	chromosome 5 open reading frame 56	5	131774571	AL564637	441108	5q31.1	Hs.658288	1
224920_x_at	0.270	5.746	2.138	4.910e-02	0.388	-4.097	MYADM	myeloid-associated differentiation marker	19	59061422, 59062948, 59064471, 59064592	AA909044	91663	19q13.42	Hs.380906	10	membrane integral to membrane
222086_s_at	0.212	4.139	2.138	4.912e-02	0.388	-4.097	WNT6	wingless-type MMTV integration site family, member 6	2	219432789	AI191771	7475	2q35	Hs.29764	11	signal transducer activity extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway cell-cell signaling multicellular organismal development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
201501_s_at	-0.381	8.926	-2.138	4.912e-02	0.388	-4.097	GRSF1	G-rich RNA sequence binding factor 1	4	-71900362, -71900362	NM_002092	2926	4q13	Hs.309763	6	mRNA binding cytoplasm mRNA polyadenylation
205560_at	0.239	4.343	2.138	4.912e-02	0.388	-4.097	PCSK5	proprotein convertase subtilisin/kexin type 5	9	77695379	NM_006200	5125	9q21.3	Hs.368542	40	kidney development kidney development renin secretion into blood stream serine-type endopeptidase activity extracellular region extracellular space Golgi apparatus Golgi lumen signal peptide processing proteolysis cell-cell signaling heart development embryo implantation peptidase activity anterior/posterior pattern formation viral assembly, maturation, egress, and release secretory granule respiratory tube development nerve growth factor processing limb morphogenesis cytokine biosynthetic process peptide binding peptide biosynthetic process embryonic gut development embryonic skeletal system development
221494_x_at	0.272	11.170	2.138	4.912e-02	0.388	-4.097	EIF3K	eukaryotic translation initiation factor 3, subunit K	19	43801561	AF085358	27335	19q13.2	Hs.314359	15	translation initiation factor activity translation initiation factor activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex regulation of translational initiation ribosome binding
221597_s_at	-0.344	6.834	-2.138	4.913e-02	0.388	-4.097	TMEM208	transmembrane protein 208	16	65818516	BC003080	29100	16q22.1	Hs.433203	2	membrane integral to membrane
212604_at	0.306	8.286	2.138	4.918e-02	0.389	-4.098	MRPS31	mitochondrial ribosomal protein S31	13	-40201431	AI937794	10240	13q14.11	Hs.154655	8	mitochondrion ribosome protein domain specific binding
243386_at	-0.326	7.551	-2.137	4.921e-02	0.389	-4.099	CASZ1	castor zinc finger 1	1	-10629856, -10619252	AI085338	54897	1p36.22	Hs.439894	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203910_at	-0.383	8.369	-2.137	4.922e-02	0.389	-4.099	ARHGAP29	Rho GTPase activating protein 29	1	-94407050	NM_004815	9411	1p22.1-p21.3	Hs.483238	8	GTPase activator activity Rho GTPase activator activity intracellular intracellular signaling cascade Rho protein signal transduction zinc ion binding diacylglycerol binding metal ion binding
235464_at	-0.250	3.380	-2.137	4.923e-02	0.389	-4.099	CSNK1A1	casein kinase 1, alpha 1	5	-148855037	AA010757	1452	5q32	Hs.529862 Hs.712555	53	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity	Wnt signaling pathway Hedgehog signaling pathway
217742_s_at	-0.259	7.767	-2.137	4.924e-02	0.389	-4.099	WAC	WW domain containing adaptor with coiled-coil	10	28861432, 28862429	NM_016628	51322		Hs.714700	15	protein binding nucleus nuclear speck
229586_at	-0.321	7.065	-2.137	4.924e-02	0.389	-4.099	CHD9	chromodomain helicase DNA binding protein 9	16	51646445	AW300405	80205	16q12.2	Hs.59159 Hs.622347	10	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription
239640_at	0.204	4.960	2.137	4.925e-02	0.389	-4.099	LOC401320	hypothetical LOC401320	7		AI221073	401320	7p15.1	Hs.561708	2
200857_s_at	-0.355	6.731	-2.137	4.925e-02	0.389	-4.099	NCOR1	nuclear receptor co-repressor 1	17	-15875982	NM_006311	9611	17p11.2	Hs.462323	112	transcription factor activity transcription corepressor activity nucleus transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter chromatin modification protein domain specific binding sequence-specific DNA binding negative regulation of transcription, DNA-dependent
224567_x_at	-0.549	11.875	-2.137	4.925e-02	0.389	-4.099	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	BG534952	378938	11q13.1	Hs.642877 Hs.714394	8
228976_at	0.366	5.536	2.137	4.926e-02	0.389	-4.099	ICOSLG	inducible T-cell co-stimulator ligand	21	-44471149	AA778249	23308	21q22.3	Hs.14155	29	receptor binding defense response immune response hyperosmotic response signal transduction membrane integral to membrane positive regulation of activated T cell proliferation T cell activation B cell activation	Cell adhesion molecules (CAMs)
1553447_at	-0.451	6.566	-2.137	4.926e-02	0.389	-4.100	AGBL1	ATP/GTP binding protein-like 1	15	84486245	NM_152336	123624	15q25.3	Hs.679833	5	metallocarboxypeptidase activity binding cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
202916_s_at	-0.320	7.009	-2.137	4.928e-02	0.389	-4.100	FAM20B	family with sequence similarity 20, member B	1	177261696	NM_014864	9917	1q25	Hs.719217	9	extracellular region
216927_at	0.249	4.545	2.136	4.928e-02	0.389	-4.100	KIAA0892	KIAA0892	19	19292629	AC003030	23383	19p13.11	Hs.654939 Hs.713004	8	chromatin protein binding extracellular region nucleus nucleoplasm cohesin loading complex maintenance of mitotic sister chromatid cohesion
1552330_at	-0.407	3.807	-2.136	4.929e-02	0.389	-4.100	MGC16385	hypothetical protein MGC16385	16	-88563701	NM_145039	92806	16q24.3	Hs.513832	3	protein binding
213443_at	0.246	3.046	2.136	4.929e-02	0.389	-4.100	TRADD	TNFRSF1A-associated via death domain	16	-65745589	N36774	8717	16q22	Hs.460996	68	signal transducer activity cytoplasm cytosol cytoskeleton induction of apoptosis signal transduction activation of pro-apoptotic gene products intermediate filament binding kinase binding tumor necrosis factor-mediated signaling pathway identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade receptor complex positive regulation of hair follicle development molecular adaptor activity death domain binding	Apoptosis RIG-I-like receptor signaling pathway Adipocytokine signaling pathway
217912_at	-0.277	8.380	-2.136	4.935e-02	0.389	-4.101	DUS1L	dihydrouridine synthase 1-like (S. cerevisiae)	17	-77609039	NM_022156	64118	17q25.3	Hs.514599	2	tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity FAD binding oxidation reduction
213483_at	-0.361	6.027	-2.136	4.936e-02	0.389	-4.101	PPWD1	peptidylprolyl isomerase domain and WD repeat containing 1	5	64894886	AK025679	23398	5q12.3	Hs.121432	5	peptidyl-prolyl cis-trans isomerase activity spliceosomal complex mRNA processing protein folding RNA splicing isomerase activity
231862_at	0.297	3.674	2.136	4.937e-02	0.389	-4.101	CBX5	chromobox homolog 5 (HP1 alpha homolog, Drosophila)	12	-52910996, -52910996, -52910996	AK023520	23468	12q13.13	Hs.349283	65	kinetochore chromatin chromatin binding nucleus nuclear envelope nucleolus cytoplasm chromatin assembly or disassembly chromocenter negative regulation of transcription general transcriptional repressor activity PML body enzyme binding nuclear centromeric heterochromatin
1566079_at	0.276	5.582	2.136	4.937e-02	0.389	-4.101	RPS16P5	ribosomal protein S16 pseudogene 5	6		AL833001	647190	6p12.1	Hs.675022	2
228817_at	-0.361	6.079	-2.136	4.937e-02	0.389	-4.102	ALG9	asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae)	11	-111158128, -111158128	AI085361	79796	11q23	Hs.503850	15	endoplasmic reticulum GPI anchor biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups intrinsic to endoplasmic reticulum membrane	N-Glycan biosynthesis Metabolic pathways
209140_x_at	0.461	10.715	2.135	4.938e-02	0.389	-4.102	HLA-B	major histocompatibility complex, class I, B	6	-31429627, -2770844, -2569111	L42024	3106	6p21.3	Hs.707171 Hs.77961	1101	antigen processing and presentation of peptide antigen via MHC class I protein binding membrane fraction plasma membrane integral to plasma membrane defense response immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
201931_at	0.293	10.721	2.135	4.939e-02	0.389	-4.102	ETFA	electron-transfer-flavoprotein, alpha polypeptide	15	-74295683	NM_000126	2108	15q23-q25	Hs.39925	18	mitochondrion mitochondrial matrix transport electron carrier activity oxidoreductase activity electron transport chain FAD binding
1560767_at	0.315	5.206	2.135	4.939e-02	0.389	-4.102	HCG22	HLA complex group 22	6	31129962, 2473196, 2272081	AK094433	285834	6p21.33	Hs.711596	1
235260_s_at	-0.573	5.641	-2.135	4.943e-02	0.389	-4.102	PACRGL	PARK2 co-regulated-like	4	20311133	AA398590	133015	4p15.31	Hs.479298	5	binding
1554634_at	0.224	2.427	2.135	4.943e-02	0.389	-4.102	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	13	32058591	BC039256	23047	13q12.3	Hs.716441	15	chromatin DNA binding ATP binding nucleus cell cycle mitotic sister chromatid cohesion mitosis negative regulation of cell proliferation identical protein binding cell division
200938_s_at	0.233	4.865	2.135	4.944e-02	0.389	-4.103	RERE	arginine-glutamic acid dipeptide (RE) repeats	1	-8335050, -8335050	AI920976	473	1p36.2-p36.1	Hs.463041	17	histone deacetylase complex transcription factor activity nucleus chromatin remodeling regulation of transcription, DNA-dependent NLS-bearing substrate import into nucleus multicellular organismal development poly-glutamine tract binding zinc ion binding sequence-specific DNA binding metal ion binding
216954_x_at	0.319	8.791	2.134	4.948e-02	0.389	-4.103	ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	21	-34197626	S77356	539	21q22.1-q22.2 21q22.11	Hs.409140	12	transporter activity mitochondrion mitochondrial proton-transporting ATP synthase complex mitochondrial proton-transporting ATP synthase complex plasma membrane ATP catabolic process ion transport drug binding proton transport ATPase activity mitochondrial ATP synthesis coupled proton transport proton-transporting ATP synthase complex, catalytic core F(1) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
206939_at	0.222	3.396	2.134	4.949e-02	0.389	-4.103	DCC	deleted in colorectal carcinoma	18	48120568	NM_005215	1630	18q21.3	Hs.579550	62	neuron migration transcription coactivator activity netrin receptor activity protein binding apoptosis induction of apoptosis multicellular organismal development axon guidance membrane integral to membrane spinal cord ventral commissure morphogenesis axon	Axon guidance Pathways in cancer Colorectal cancer
201630_s_at	-0.361	8.765	-2.134	4.950e-02	0.389	-4.104	ACP1	acid phosphatase 1, soluble	2	254868, 254868	NM_004300	52	2p25	Hs.558296	69	acid phosphatase activity non-membrane spanning protein tyrosine phosphatase activity soluble fraction cytoplasm protein amino acid dephosphorylation hydrolase activity identical protein binding	gamma-Hexachlorocyclohexane degradation Riboflavin metabolism Adherens junction
213188_s_at	-0.398	7.334	-2.134	4.950e-02	0.389	-4.104	MINA	MYC induced nuclear antigen	3	-99143350, -99143350	AI823896	84864	3q11.2	Hs.607776	15	nucleus nucleolus cytoplasm ribosome biogenesis
221022_s_at	0.202	5.485	2.134	4.951e-02	0.389	-4.104	PMFBP1	polyamine modulated factor 1 binding protein 1	16	-70710497, -70710497	NM_031293	83449	16q22.2	Hs.714939	10	cytoplasm
1560320_a_at	0.265	4.492	2.134	4.952e-02	0.389	-4.104	UNQ2963	hypothetical LOC283314	12	7152179	AL833364	283314	12p13.31	Hs.715709	2
226987_at	0.211	5.537	2.134	4.952e-02	0.389	-4.104	RBM15B	RNA binding motif protein 15B	3	51403770	W68720	29890	3p21.2	Hs.118738	6	nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus mRNA processing nucleocytoplasmic transport RNA splicing negative regulation of transcription interspecies interaction between organisms
227954_at	-0.304	6.163	-2.134	4.954e-02	0.389	-4.104	ITPRIPL2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	16	19032754	AI458417	162073	16p12.3	Hs.530899 Hs.648523	3	membrane integral to membrane
216129_at	0.326	5.044	2.134	4.954e-02	0.389	-4.104	ATP9A	ATPase, class II, type 9A	20	-49646720	AL117659	10079	20q13.2	Hs.719117	6	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
231870_s_at	-0.194	8.640	-2.134	4.955e-02	0.389	-4.105	NMD3	NMD3 homolog (S. cerevisiae)	3	162421792	BG291007	51068	3q26.1	Hs.598836	8	nucleus nucleoplasm nucleolus cytoplasm protein transport
213467_at	0.286	4.709	2.134	4.956e-02	0.389	-4.105	RND2	Rho family GTPase 2	17	38430783	BF511718	8153	17q21	Hs.603111	16	nucleotide binding GTPase activity protein binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction
204652_s_at	-0.270	5.531	-2.133	4.958e-02	0.389	-4.105	NRF1	nuclear respiratory factor 1	7	129038790, 129057154	NM_005011	4899	7q32	Hs.654363	47	DNA binding nucleus generation of precursor metabolites and energy regulation of transcription from RNA polymerase II promoter regulation of transcription	Huntington's disease
215818_at	0.215	4.591	2.133	4.959e-02	0.389	-4.105	NUDT7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	16	76313911, 76313911	AK026469	283927	16q23.1	Hs.719356	2	magnesium ion binding peroxisome nucleoside diphosphate metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides manganese ion binding
210732_s_at	-0.446	2.848	-2.133	4.960e-02	0.389	-4.106	LGALS8	lectin, galactoside-binding, soluble, 8	1	234748187, 234753361, 234753699	AF342816	3964	1q42-q43	Hs.4082 Hs.708114	29	sugar binding extracellular space cytoplasm
227731_at	-0.582	7.974	-2.133	4.961e-02	0.389	-4.106	CNBP	CCHC-type zinc finger, nucleic acid binding protein	3	-130369347	BF063728	7555	3q21	Hs.518249	24	transcription factor activity protein binding cytoplasm endoplasmic reticulum regulation of transcription, DNA-dependent cholesterol biosynthetic process zinc ion binding metal ion binding
237656_at	0.295	4.101	2.133	4.963e-02	0.389	-4.106	WWC2	WW and C2 domain containing 2	4	184257456	BG149582	80014	4q35.1	Hs.333179	5	protein binding
208729_x_at	0.416	9.421	2.133	4.964e-02	0.389	-4.106	HLA-B	major histocompatibility complex, class I, B	6	-31429627, -2770844, -2569111	D83043	3106	6p21.3	Hs.707171 Hs.77961	1101	antigen processing and presentation of peptide antigen via MHC class I protein binding membrane fraction plasma membrane integral to plasma membrane defense response immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
211752_s_at	0.312	10.483	2.133	4.965e-02	0.389	-4.106	NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	19	1334882	BC005954	374291	19p13.3	Hs.211914	20	NADH dehydrogenase activity iron ion binding protein binding mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor electron transport chain mitochondrial respiratory chain complex I assembly metal ion binding quinone binding 4 iron, 4 sulfur cluster binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
244317_at	0.432	4.230	2.133	4.965e-02	0.389	-4.106	KIAA1324L	KIAA1324-like	7	-86347173, -86347173	BF035563	222223	7q21.12	Hs.208093	3	G-protein coupled receptor activity protein binding G-protein coupled receptor protein signaling pathway membrane integral to membrane
221255_s_at	0.214	9.635	2.132	4.966e-02	0.389	-4.107	TMEM93	transmembrane protein 93	17	3518838	NM_031298	83460	17p13.2	Hs.30011	3	membrane integral to membrane
201040_at	0.328	6.118	2.132	4.967e-02	0.389	-4.107	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	3	50248650	NM_002070	2771	3p21	Hs.77269	85	nucleotide binding activation of MAPKK activity adenosine receptor signaling pathway GTPase activity signal transducer activity protein binding GTP binding membrane fraction nucleus cytosol plasma membrane signal transduction inhibition of adenylate cyclase activity by G-protein signaling muscarinic acetylcholine receptor signaling pathway gamma-aminobutyric acid signaling pathway protein kinase cascade response to nutrient positive regulation of cell proliferation guanyl nucleotide binding membrane raft negative regulation of synaptic transmission negative regulation of calcium ion transport via voltage-gated calcium channel activity	Chemokine signaling pathway Axon guidance Tight junction Gap junction Leukocyte transendothelial migration Long-term depression Melanogenesis
1554428_s_at	0.237	6.944	2.132	4.969e-02	0.389	-4.107	NLGN2	neuroligin 2	17	7252225	AF376802	57555	17p13.1	Hs.26229	11	regulation of respiratory gaseous exchange by neurological system process synaptogenesis integral to membrane cell-cell adhesion neurexin binding synapse postsynaptic membrane cell-cell junction maintenance regulation of synaptic transmission	Cell adhesion molecules (CAMs)
213803_at	-0.370	7.794	-2.132	4.971e-02	0.389	-4.107	KPNB1	karyopherin (importin) beta 1	17	43082273	BG545463	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
213203_at	-0.368	8.967	-2.132	4.971e-02	0.389	-4.107	SNAPC5	small nuclear RNA activating complex, polypeptide 5, 19kDa	15	-64569719	AI633709	10302	15q22.31	Hs.30174	7	transcription factor activity nucleus transcription from RNA polymerase II promoter transcription initiation from RNA polymerase III promoter regulation of transcription
213514_s_at	-0.269	6.710	-2.132	4.972e-02	0.389	-4.108	DIAPH1	diaphanous homolog 1 (Drosophila)	5	-140874771	AU158818	1729	5q31	Hs.529451	33	actin binding receptor binding cytoplasm cytoskeleton plasma membrane sensory perception of sound cellular component organization Rho GTPase binding actin cytoskeleton organization ruffle membrane cell projection	Focal adhesion Regulation of actin cytoskeleton
230059_at	0.213	5.766	2.131	4.976e-02	0.390	-4.108	DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	11	-634224	AI052714	10522	11p15.5	Hs.243994	15	DNA binding binding extracellular region nucleus transcription from RNA polymerase II promoter germ cell development zinc ion binding anatomical structure morphogenesis regulation of transcription metal ion binding
205633_s_at	0.820	8.371	2.131	4.979e-02	0.390	-4.109	ALAS1	aminolevulinate, delta-, synthase 1	3	52207155, 52207183	NM_000688	211	3p21.1	Hs.476308	24	5-aminolevulinate synthase activity mitochondrion mitochondrial matrix heme biosynthetic process acyltransferase activity transferase activity, transferring nitrogenous groups pyridoxal phosphate binding tetrapyrrole biosynthetic process	Glycine, serine and threonine metabolism Porphyrin and chlorophyll metabolism Metabolic pathways
219331_s_at	0.336	5.177	2.131	4.979e-02	0.390	-4.109	KLHDC8A	kelch domain containing 8A	1	-203572270	NM_018203	55220	1q32.1	Hs.10414	3
1553126_a_at	-0.293	2.614	-2.131	4.980e-02	0.390	-4.109	SLC39A12	solute carrier family 39 (zinc transporter), member 12	10	18280773	NM_152725	221074	10p12.33	Hs.350895	4	ion transport zinc ion transport zinc ion binding membrane integral to membrane metal ion transport metal ion transmembrane transporter activity
212978_at	-0.498	5.287	-2.131	4.981e-02	0.390	-4.109	LRRC8B	leucine rich repeat containing 8 family, member B	1	89762984, 89796859	AU146004	23507	1p22.2	Hs.482017 Hs.632420	6	protein binding membrane integral to membrane
222678_s_at	-0.411	5.781	-2.131	4.983e-02	0.390	-4.109	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	3	-184143252	BF057821	54165	3q26.3	Hs.715661	16	molecular_function cellular_component biological_process modification-dependent protein catabolic process
221589_s_at	0.682	8.211	2.131	4.984e-02	0.390	-4.110	ALDH6A1	aldehyde dehydrogenase 6 family, member A1	14	-73596624	AW612403	4329	14q24.3	Hs.293970	9	acyl-CoA binding methylmalonate-semialdehyde dehydrogenase (acylating) activity mitochondrion valine metabolic process oxidoreductase activity malonate-semialdehyde dehydrogenase (acetylating) activity thymine metabolic process brown fat cell differentiation oxidation reduction	Valine, leucine and isoleucine degradation Inositol phosphate metabolism Propanoate metabolism Metabolic pathways
238034_at	-0.328	6.690	-2.130	4.985e-02	0.390	-4.110	CANX	calnexin	5	179058535	AI890021	821	5q35	Hs.699155	90	calcium ion binding sugar binding endoplasmic reticulum protein folding protein secretion membrane integral to membrane melanosome unfolded protein binding	Antigen processing and presentation
227840_at	0.347	5.525	2.130	4.986e-02	0.390	-4.110	C2orf76	chromosome 2 open reading frame 76	2	-119776489	AA738440	130355	2q14.2	Hs.99488	1
220120_s_at	0.297	2.656	2.130	4.988e-02	0.390	-4.110	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A	5	-111526213	NM_022140	64097	5q22.1-q22.2	Hs.584954	7	binding cellular_component cytoplasm cytoskeleton cytoskeletal protein binding biological_process extrinsic to membrane
219928_s_at	0.272	3.368	2.130	4.989e-02	0.390	-4.110	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated	18	19972952, 19973445	NM_012189	26256	18q11.2	Hs.511983	11	calcium ion binding nucleus cytoplasm cytoskeleton cilium signal transduction cAMP-dependent protein kinase regulator activity flagellum
209091_s_at	-0.225	9.414	-2.130	4.989e-02	0.390	-4.110	SH3GLB1	SH3-domain GRB2-like endophilin B1	1	86942844	AF263293	51100	1p22	Hs.136309	28	protein insertion into mitochondrial membrane during induction of apoptosis fatty acid binding protein binding nucleus cytoplasm mitochondrion mitochondrial outer membrane microsome Golgi apparatus phosphatidic acid biosynthetic process apoptosis anti-apoptosis phospholipid biosynthetic process membrane lysophosphatidic acid acyltransferase activity protein homodimerization activity protein complex 'de novo' posttranslational protein folding	Endocytosis
1570015_at	0.256	2.582	2.130	4.991e-02	0.390	-4.111	RP11-165H20.1	CHIA-like pseudogene	1	111624668	BC031662	149620	1p13.2		1
217824_at	-0.315	5.019	-2.130	4.991e-02	0.390	-4.111	UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)	6	-90093062	AW500009	51465	6q15	Hs.163776	12	nucleotide binding ubiquitin-protein ligase activity ATP binding endoplasmic reticulum membrane integral to membrane ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
212952_at	-0.371	6.783	-2.129	4.995e-02	0.390	-4.111	CALR	calreticulin	19	12910413	AA910371	811	19p13.3-p13.2	Hs.515162	126	negative regulation of transcription from RNA polymerase II promoter complement component C1q binding peptide antigen assembly with MHC class I protein complex DNA binding mRNA binding integrin binding calcium ion binding sugar binding extracellular region proteinaceous extracellular matrix extracellular space nucleus cytoplasm endoplasmic reticulum endoplasmic reticulum lumen microsome cytosol polysome regulation of transcription, DNA-dependent protein export from nucleus cell cycle arrest zinc ion binding positive regulation of cell proliferation ferredoxin reductase activity external side of plasma membrane senescence transcription repressor activity negative regulation of translation negative regulation of translation protein maturation by protein folding cortical actin cytoskeleton organization negative regulation of steroid hormone receptor signaling pathway regulation of meiosis MHC class I peptide loading complex glucocorticoid receptor signaling pathway regulation of apoptosis negative regulation of neuron differentiation positive regulation of DNA replication positive regulation of cell cycle negative regulation of retinoic acid receptor signaling pathway perinuclear region of cytoplasm androgen receptor binding positive regulation of phagocytosis protein stabilization unfolded protein binding chaperone binding sequestering of calcium ion	Antigen processing and presentation
236573_at	0.641	10.726	2.129	4.995e-02	0.390	-4.112	MIB1	mindbomb homolog 1 (Drosophila)	18	17575542	AI819052	57534	18q11.2	Hs.140903 Hs.658808	15	blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding
1564204_at	0.199	3.613	2.129	4.996e-02	0.390	-4.112	FAM91A2	family with sequence similarity 91, member A2	1		AK090660	57234	1q21.1	Hs.710717	3
226261_at	-0.294	3.504	-2.129	4.996e-02	0.390	-4.112	ZNRF2	zinc and ring finger 2	7	30290447	AI831561	223082	7p14.3	Hs.487869	4	protein binding lysosome endosome plasma membrane zinc ion binding ligase activity modification-dependent protein catabolic process cell junction synapse metal ion binding
211748_x_at	0.729	9.220	2.129	4.997e-02	0.390	-4.112	PTGDS	prostaglandin D2 synthase 21kDa (brain)	9	138991776	BC005939	5730	9q34.2-q34.3	Hs.446429	63	prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm	Arachidonic acid metabolism Metabolic pathways
1553268_at	0.291	4.238	2.129	4.998e-02	0.390	-4.112	RHBDL3	rhomboid, veinlet-like 3 (Drosophila)	17	27617307	NM_138328	162494	17q11.2	Hs.655027	3	serine-type endopeptidase activity calcium ion binding signal transduction peptidase activity membrane integral to membrane
225310_at	-0.291	7.261	-2.129	4.999e-02	0.390	-4.112	RBMX	RNA binding motif protein, X-linked	X	-135783284	AI928344	27316	Xq26.3	Hs.380118 Hs.710162	32	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex biological_process RNA splicing heterogeneous nuclear ribonucleoprotein complex

5729 Genes