Bioconductor Affymetrix Probe Listing

Probe	log2FC	AveExpr	t	P.Value	adj.P.Val	B	Symbol	Description	Chromosome	Chromosome Location	GenBank	Gene	Cytoband	UniGene	PubMed	Gene Ontology	Pathway
217963_s_at	2.041	8.334	10.739	1.686e-08	0.001	9.003	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	X	102517923, 102518764	NM_014380	27018	Xq22.2	Hs.448588 Hs.719133	17	protein binding nucleus cytoplasm apoptosis multicellular organismal development metal ion binding	Neurotrophin signaling pathway
242414_at	1.435	5.714	10.398	2.607e-08	0.001	8.665	QPRT	quinolinate phosphoribosyltransferase	16	29597941	AW960707	23475	16p11.2	Hs.513484	8	nicotinate-nucleotide diphosphorylase (carboxylating) activity nicotinate-nucleotide diphosphorylase (carboxylating) activity cellular_component cytosol metabolic process NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process quinolinate catabolic process protein homodimerization activity protein oligomerization	Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
209075_s_at	-1.025	11.329	-9.860	5.296e-08	0.001	8.106	ISCU	iron-sulfur cluster scaffold homolog (E. coli)	12	107480423	AY009128	23479	12q24.1	Hs.615131	14	iron ion binding nucleus cytoplasm mitochondrion cytosol nitrogen fixation iron-sulfur cluster assembly protein complex scaffold metal ion binding iron-sulfur cluster binding
224324_at	1.109	5.004	9.833	5.497e-08	0.001	8.076	MRO	maestro	18	-46575487, -46575487	AB042647	83876	18q21	Hs.30495	6	binding nucleus nucleolus
224323_s_at	1.088	5.975	9.741	6.221e-08	0.001	7.977	MRO	maestro	18	-46575487, -46575487	AB042647	83876	18q21	Hs.30495	6	binding nucleus nucleolus
228044_at	0.904	5.006	9.490	8.777e-08	0.001	7.700	SERP2	stress-associated endoplasmic reticulum protein family member 2	13	43845977	AI420319	387923	13q14.11	Hs.377972	4	endoplasmic reticulum protein transport membrane integral to membrane intracellular protein transmembrane transport
219765_at	2.571	4.909	9.278	1.180e-07	0.001	7.460	ZNF329	zinc finger protein 329	19	-63329506	NM_024620	79673	19q13.43	Hs.458377	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
227558_at	1.311	6.002	9.278	1.180e-07	0.001	7.459	CBX4	chromobox homolog 4 (Pc class homolog, Drosophila)	17	-75421549	AI570531	8535	17q25.3	Hs.714363	25	chromatin chromatin binding transcription corepressor activity nucleus chromatin assembly or disassembly anti-apoptosis negative regulation of transcription chromatin modification enzyme binding modification-dependent protein catabolic process
1557260_a_at	1.802	2.670	8.944	1.900e-07	0.001	7.068	ZNF382	zinc finger protein 382	19	41788060	BM973530	84911	19q13.12	Hs.631591	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
219073_s_at	2.007	4.964	8.644	2.946e-07	0.001	6.703	OSBPL10	oxysterol binding protein-like 10	3	-31677320	NM_017784	114884	3p22.3	Hs.150122	7	lipid transport steroid metabolic process
204044_at	1.433	5.567	8.554	3.367e-07	0.002	6.591	QPRT	quinolinate phosphoribosyltransferase	16	29597941	NM_014298	23475	16p11.2	Hs.513484	8	nicotinate-nucleotide diphosphorylase (carboxylating) activity nicotinate-nucleotide diphosphorylase (carboxylating) activity cellular_component cytosol metabolic process NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process quinolinate catabolic process protein homodimerization activity protein oligomerization	Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
222431_at	1.181	6.362	8.503	3.635e-07	0.002	6.527	SPIN1	spindlin 1	9	90193116	AL136719	10927	9q22.1-q22.3	Hs.146804	16	nucleus spindle cell cycle multicellular organismal development gamete generation
204400_at	0.948	4.839	8.089	6.821e-07	0.002	5.994	EFS	embryonal Fyn-associated substrate	14	-22895450	NM_005864	10278	14q11.2-q12	Hs.24587	8	cytoplasm cell adhesion intracellular signaling cascade SH3 domain binding
220183_s_at	1.112	6.738	8.022	7.563e-07	0.003	5.905	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	4	-124033248, -124033248	NM_007083	11162	4q26	Hs.558459	15	cellular_component growth factor activity biological_process hydrolase activity
201462_at	1.163	4.520	7.959	8.349e-07	0.003	5.821	SCRN1	secernin 1	7	-29926244, -29926244, -29926244	NM_014766	9805	7p14.3-p14.1	Hs.520740	11	molecular_function nucleus cytoplasm exocytosis nuclear membrane
202203_s_at	-1.560	7.181	-7.959	8.349e-07	0.003	5.821	AMFR	autocrine motility factor receptor	16	-54952864	NM_001144	267	16q21	Hs.295137	33	protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization
209005_at	0.774	7.759	7.910	9.008e-07	0.003	5.756	FBXL5	F-box and leucine-rich repeat protein 5	4	-15215251	AF157323	26234	4p15.32	Hs.643433	13	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process
225817_at	0.877	4.119	7.836	1.012e-06	0.003	5.655	CGNL1	cingulin-like 1	15	55455996	AB051536	84952	15q21.3	Hs.148989	6	motor activity tight junction myosin complex cell junction
230919_at	1.223	3.345	7.800	1.072e-06	0.003	5.605	ZNF233	zinc finger protein 233	19	49455915	AW006620	353355	19q13.31	Hs.466891	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
215307_at	0.852	3.799	7.516	1.687e-06	0.004	5.213	ZNF529	zinc finger protein 529	19	-41762996, -41726357, -41726357	AL109722	57711	19q13.13	Hs.708146	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229377_at	-0.953	5.872	-7.498	1.739e-06	0.004	5.187	GRTP1	growth hormone regulated TBC protein 1	13	-113026505	BF001483	79774	13q34	Hs.170904	3	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
230329_s_at	1.135	7.493	7.399	2.041e-06	0.005	5.047	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	4	-124033248, -124033248	AI580268	11162	4q26	Hs.558459	15	cellular_component growth factor activity biological_process hydrolase activity
203423_at	2.246	6.369	7.382	2.100e-06	0.005	5.022	RBP1	retinol binding protein 1, cellular	3	-140727937, -140727317, -140718965	NM_002899	5947	3q23	Hs.529571	31	transporter activity cytoplasm transport lipid binding retinal binding retinol binding retinol metabolic process retinoic acid metabolic process
229160_at	-1.599	7.231	-7.299	2.407e-06	0.005	4.903	MUM1L1	melanoma associated antigen (mutated) 1-like 1	X	105307974	AI967987	139221	Xq22.3	Hs.592221	5
223192_at	0.682	8.030	7.283	2.470e-06	0.005	4.880	SLC25A28	solute carrier family 25, member 28	10	-101360264	AF267854	81894	10q23-q24	Hs.403790	6	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
1558487_a_at	0.905	7.829	7.168	2.991e-06	0.006	4.712	TMED4	transmembrane emp24 protein transport domain containing 4	7	-44585286	AK074557	222068	7p13	Hs.598832 Hs.715273	11	endoplasmic reticulum transport membrane integral to membrane
218312_s_at	1.098	7.394	7.089	3.410e-06	0.006	4.597	ZSCAN18	zinc finger and SCAN domain containing 18	19	-63310783, -63287021, -63287021	NM_023926	65982	19q13.43	Hs.235390	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204309_at	0.699	4.458	7.084	3.438e-06	0.006	4.590	CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	15	-72417155, -72417155	NM_000781	1583	15q23-q24	Hs.303980	88	monooxygenase activity mitochondrion lipid metabolic process C21-steroid hormone biosynthetic process cholesterol metabolic process cholesterol metabolic process cholesterol monooxygenase (side-chain-cleaving) activity cholesterol monooxygenase (side-chain-cleaving) activity electron carrier activity membrane heme binding mitochondrial membrane vitamin D metabolic process metal ion binding oxidation reduction	C21-Steroid hormone metabolism Metabolic pathways
243924_at	1.395	3.740	6.919	4.540e-06	0.007	4.344	LOC100127980	hypothetical protein LOC100127980	19		AA781404	100127980	19q13.12	Hs.595153	1
228332_s_at	-0.532	9.953	-6.917	4.562e-06	0.007	4.340	C11orf31	chromosome 11 open reading frame 31	11	57265297	AA526939	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
204671_s_at	0.992	5.498	6.908	4.627e-06	0.007	4.327	ANKRD6	ankyrin repeat domain 6	6	90199615	BE677131	22881	6q14.2-q16.1	Hs.702213	9	protein binding
200994_at	-0.552	10.164	-6.848	5.127e-06	0.008	4.236	IPO7	importin 7	11	9362744	BG291787	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
224928_at	-0.908	9.894	-6.750	6.063e-06	0.009	4.087	SETD7	SET domain containing (lysine methyltransferase) 7	4	-140646641	AK024846	80854	4q28	Hs.480792	21	protein binding nucleus chromosome regulation of transcription, DNA-dependent methyltransferase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity	Lysine degradation
236328_at	0.701	4.744	6.663	7.054e-06	0.010	3.952	ZNF285A	zinc finger protein 285A	19	-49581647	AW513227	26974		Hs.709428	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
223373_s_at	0.925	8.632	6.662	7.060e-06	0.010	3.951	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AF306567	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
227379_at	0.912	5.055	6.656	7.141e-06	0.010	3.941	MBOAT1	membrane bound O-acyltransferase domain containing 1	6	-20208913	AI734993	154141	6p22.3	Hs.377830	7	acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
210445_at	0.571	4.524	6.607	7.773e-06	0.010	3.865	FABP6	fatty acid binding protein 6, ileal	5	159546951, 159558625, 159589014	U19869	2172	5q33.3-q34	Hs.519719	18	transporter activity fatty acid binding cytoplasm cytosol lipid metabolic process transport steroid metabolic process negative regulation of cell proliferation	PPAR signaling pathway
202646_s_at	-0.712	11.463	-6.517	9.093e-06	0.011	3.725	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	AA167775	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
203178_at	-2.178	8.782	-6.470	9.881e-06	0.012	3.651	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	NM_001482	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
221432_s_at	0.709	7.402	6.383	1.151e-05	0.013	3.513	SLC25A28	solute carrier family 25, member 28	10	-101360264	NM_031212	81894	10q23-q24	Hs.403790	6	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
200915_x_at	-0.730	11.862	-6.382	1.155e-05	0.013	3.511	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	NM_004986	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
224476_s_at	0.769	7.217	6.362	1.196e-05	0.014	3.479	MESP1	mesoderm posterior 1 homolog (mouse)	15	-88094103	BC006219	55897	15q26.1	Hs.447531	4	heart morphogenesis DNA binding nucleus Notch signaling pathway multicellular organismal development mesodermal cell migration transcription regulator activity regulation of transcription
214709_s_at	-0.796	11.707	-6.312	1.305e-05	0.014	3.400	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	Z22551	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
238049_at	0.748	3.958	6.304	1.326e-05	0.014	3.387	GRAMD3	GRAM domain containing 3	5	125723686, 125786767, 125828685	AW971198	65983	5q23.2	Hs.363558	6
223680_at	0.574	3.733	6.287	1.367e-05	0.014	3.359	ZNF607	zinc finger protein 607	19	-42879115	BC005085	84775	19q13.1	Hs.116622	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
227542_at	-1.040	7.379	-6.284	1.373e-05	0.014	3.355	SOCS6	suppressor of cytokine signaling 6	18	66107116	AU157543	9306	18q22.2	Hs.44439	13	protein binding cytoplasm defense response intracellular signaling cascade JAK-STAT cascade negative regulation of signal transduction modification-dependent protein catabolic process regulation of growth
219584_at	2.428	5.503	6.249	1.463e-05	0.014	3.298	PLA1A	phospholipase A1 member A	3	120799411	NM_015900	51365	3q13.13-q13.2	Hs.437451	11	extracellular region phosphatidylserine metabolic process phospholipase A1 activity lipid catabolic process hydrolase activity	Tropane, piperidine and pyridine alkaloid biosynthesis
238952_x_at	0.508	3.760	6.245	1.472e-05	0.014	3.292	ZNF829	zinc finger protein 829	19	-42074092	BF439163	374899	19q13.12	Hs.124047	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1553177_at	-2.066	6.108	-6.240	1.487e-05	0.014	3.283	SH2D1B	SH2 domain containing 1B	1	-160631679	BC022407	117157	1q23.3	Hs.350581	10	molecular_function protein binding cellular_component biological_process	Natural killer cell mediated cytotoxicity
224580_at	0.691	4.144	6.227	1.522e-05	0.014	3.262	SLC38A1	solute carrier family 38, member 1	12	-44863107	BF515894	81539	12q13.11	Hs.694701	11	sodium:amino acid symporter activity membrane fraction plasma membrane ion transport sodium ion transport glutamine transport L-glutamine transmembrane transporter activity symporter activity integral to membrane axon sodium ion binding
205374_at	-0.591	13.454	-6.226	1.524e-05	0.014	3.261	SLN	sarcolipin	11	-107083310	NM_003063	6588	11q22-q23	Hs.334629	12	membrane integral to membrane sarcoplasmic reticulum enzyme regulator activity regulation of calcium ion transport
226676_at	0.750	4.388	6.219	1.541e-05	0.014	3.251	ZNF521	zinc finger protein 521	18	-20895885	AK021452	25925	18q11.2	Hs.116935	9
229012_at	0.711	5.291	6.191	1.623e-05	0.014	3.204	C9orf24	chromosome 9 open reading frame 24	9	-34369016, -34369016	AW269443	84688	9p13.3	Hs.50334	8
219449_s_at	-1.560	10.923	-6.181	1.652e-05	0.014	3.188	TMEM70	transmembrane protein 70	8	75050983	NM_017866	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
238592_at	-2.219	8.949	-6.171	1.682e-05	0.014	3.172	PDLIM3	PDZ and LIM domain 3	4	-186659844	BE840636	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
214643_x_at	-0.779	9.148	-6.164	1.703e-05	0.014	3.161	BIN1	bridging integrator 1	2	-127522077, -127522076	BG034080	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
202942_at	0.981	9.610	6.161	1.712e-05	0.014	3.156	ETFB	electron-transfer-flavoprotein, beta polypeptide	19	-56540220, -56540220	NM_001985	2109	19q13.3	Hs.348531	16	mitochondrion mitochondrial matrix transport electron carrier activity electron transport chain
242323_at	0.812	8.505	6.151	1.743e-05	0.014	3.140	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AV714268	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
219441_s_at	0.726	5.096	6.150	1.745e-05	0.014	3.139	LRRK1	leucine-rich repeat kinase 1	15	99276982	NM_024652	79705	15q26.3	Hs.407918	16	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding GTP binding intracellular cytoplasm protein amino acid phosphorylation small GTPase mediated signal transduction transferase activity manganese ion binding
231871_at	0.665	4.686	6.127	1.820e-05	0.015	3.101	GPR180	G protein-coupled receptor 180	13	94052104	AU160685	160897	13q32.1	Hs.657472	7	membrane integral to membrane
201860_s_at	0.799	5.248	6.081	1.978e-05	0.015	3.025	PLAT	plasminogen activator, tissue	8	-42151392	NM_000930	5327	8p12	Hs.491582	209	serine-type endopeptidase activity extracellular region extracellular region extracellular space protein modification process proteolysis blood coagulation peptidase activity	Complement and coagulation cascades
222975_s_at	-0.801	10.872	-6.081	1.980e-05	0.015	3.024	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	AI423180	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
205311_at	0.946	4.213	6.080	1.982e-05	0.015	3.023	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7	-50493627, -50493627	NM_000790	1644	7p12.2	Hs.359698	48	aromatic-L-amino-acid decarboxylase activity protein binding cellular amino acid and derivative metabolic process response to toxin lyase activity carboxylic acid metabolic process pyridoxal phosphate binding catecholamine biosynthetic process	Histidine metabolism Tyrosine metabolism Phenylalanine metabolism Tryptophan metabolism Isoquinoline alkaloid biosynthesis Betalain biosynthesis Biosynthesis of alkaloids derived from shikimate pathway Metabolic pathways
203466_at	0.568	6.450	6.079	1.986e-05	0.015	3.021	MPV17	MpV17 mitochondrial inner membrane protein	2	-27385863	NM_002437	4358	2p23.3	Hs.75659	17	mitochondrial genome maintenance molecular_function mitochondrion mitochondrial inner membrane integral to peroxisomal membrane oxygen and reactive oxygen species metabolic process membrane integral to membrane homeostatic process
219926_at	-0.790	10.266	-6.077	1.995e-05	0.015	3.018	POPDC3	popeye domain containing 3	6	-105712475, -105712475	NM_022361	64208	6q21	Hs.458336	7	molecular_function biological_process membrane integral to membrane
206891_at	-3.638	9.865	-6.065	2.038e-05	0.015	2.998	ACTN3	actinin, alpha 3	11	66070966	NM_001104	89	11q13.1	Hs.654432	47	actin binding integrin binding calcium ion binding protein binding actin filament focal adhesion structural constituent of muscle pseudopodium protein homodimerization activity regulation of apoptosis focal adhesion formation	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
219939_s_at	-0.559	12.053	-6.048	2.101e-05	0.015	2.971	CSDE1	cold shock domain containing E1, RNA-binding	1	-115061060, -115061060, -115061059	NM_007158	7812	1p22	Hs.69855	25	DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development
1558233_s_at	-0.808	7.094	-6.038	2.138e-05	0.015	2.955	ATF1	activating transcription factor 1	12	49444085	CA337502	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
205730_s_at	1.146	6.986	6.032	2.161e-05	0.015	2.945	ABLIM3	actin binding LIM protein family, member 3	5	148501246	NM_014945	22885	5q32	Hs.49688	15	actin binding cytoplasm cytoskeleton organization zinc ion binding positive regulation of transcription from RNA polymerase II promoter metal ion binding	Axon guidance
220565_at	1.016	4.568	6.023	2.198e-05	0.015	2.930	CCR10	chemokine (C-C motif) receptor 10	17	-38084945	NM_016602	2826	17q21.1-q21.3	Hs.719562	20	receptor activity G-protein coupled receptor activity protein binding plasma membrane integral to plasma membrane chemotaxis signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration C-C chemokine receptor activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
215286_s_at	-0.674	4.704	-6.007	2.262e-05	0.015	2.904	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AL050389	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
214356_s_at	-0.605	9.260	-5.981	2.373e-05	0.016	2.860	KIAA0368	KIAA0368	9	-113162793	AI272899	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
235082_at	-0.907	4.866	-5.960	2.468e-05	0.016	2.825	PCNX	pecanex homolog (Drosophila)	14	70443874	BG024649	22990	14q24.2	Hs.446559	10	membrane integral to membrane
228450_at	0.794	3.691	5.955	2.491e-05	0.016	2.816	PLEKHA7	pleckstrin homology domain containing, family A member 7	11	-16765787	AA758861	144100	11p15.1	Hs.12332	4	protein binding
204607_at	3.820	7.980	5.906	2.726e-05	0.017	2.734	HMGCS2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	1	-120092525	NM_005518	3158	1p13-p12	Hs.59889	13	hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity mitochondrion mitochondrial inner membrane mitochondrial matrix cholesterol biosynthetic process response to nutrient metabolic process isoprenoid biosynthetic process transferase activity response to drug response to peptide hormone stimulus	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
220703_at	1.773	7.471	5.903	2.738e-05	0.017	2.730	C10orf110	chromosome 10 open reading frame 110	10	1058576	NM_018470	55853	10p15.3	Hs.644603	2
224870_at	0.952	9.168	5.890	2.802e-05	0.017	2.709	KIAA0114	KIAA0114	4	53273377	BG255416	57291	4q12	Hs.17719	4
201975_at	-0.588	9.896	-5.885	2.830e-05	0.017	2.700	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	NM_002956	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
242794_at	0.828	3.715	5.876	2.880e-05	0.017	2.684	MAML3	mastermind-like 3 (Drosophila)	4	-140856995	AI569476	55534	4q28	Hs.586165	7	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
230904_at	-1.310	5.557	-5.872	2.897e-05	0.017	2.679	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	W42665	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
201030_x_at	1.779	10.837	5.870	2.908e-05	0.017	2.675	LDHB	lactate dehydrogenase B	12	-21679542	NM_002300	3945	12p12.2-p12.1	Hs.446149	27	L-lactate dehydrogenase activity binding cytoplasm oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
231358_at	0.655	5.244	5.847	3.038e-05	0.017	2.636	MRO	maestro	18	-46575487, -46575487	BE465760	83876	18q21	Hs.30495	6	binding nucleus nucleolus
212307_s_at	-0.630	7.187	-5.841	3.069e-05	0.017	2.626	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	70669657	BF001665	8473	Xq13	Hs.405410	47	protein binding nucleus cytoplasm cytosol protein amino acid O-linked glycosylation signal transduction response to nutrient acetylglucosaminyltransferase activity transferase activity, transferring glycosyl groups MLL5-L complex	O-Glycan biosynthesis Metabolic pathways
200789_at	0.726	10.678	5.839	3.081e-05	0.017	2.623	ECH1	enoyl Coenzyme A hydratase 1, peroxisomal	19	-43997901	NM_001398	1891	19q13.1	Hs.196176	9	enoyl-CoA hydratase activity protein binding mitochondrion peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process isomerase activity	Tyrosine metabolism
200972_at	-0.915	10.380	-5.836	3.100e-05	0.017	2.617	TSPAN3	tetraspanin 3	15	-75125385	BC000704	10099	15q24.3	Hs.5062 Hs.716484	8	membrane integral to membrane
200995_at	-0.960	8.955	-5.826	3.158e-05	0.017	2.600	IPO7	importin 7	11	9362744	AI741392	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
212552_at	0.618	6.716	5.817	3.209e-05	0.017	2.586	HPCAL1	hippocalcin-like 1	2	10360490, 10361276	BE617588	3241	2p25.1	Hs.467696 Hs.580427	20	calcium ion binding protein binding
218735_s_at	1.195	5.646	5.806	3.275e-05	0.017	2.567	ZNF544	zinc finger protein 544	19	63431881	AA349848	27300	19q13.43	Hs.438994	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1555793_a_at	0.879	4.722	5.799	3.318e-05	0.017	2.555	ZFP82	zinc finger protein 82 homolog (mouse)	19	-41574700	AL834267	284406	19q13.12	Hs.558734	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214039_s_at	-1.126	11.019	-5.793	3.355e-05	0.017	2.545	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	T15777	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
201904_s_at	1.193	6.793	5.791	3.367e-05	0.017	2.542	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF031714	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
217975_at	0.831	7.011	5.790	3.371e-05	0.017	2.541	WBP5	WW domain binding protein 5	X	102498035	NM_016303	51186	Xq22.2	Hs.533287	6	protein binding WW domain binding
202204_s_at	-0.669	7.366	-5.790	3.374e-05	0.017	2.540	AMFR	autocrine motility factor receptor	16	-54952864	AF124145	267	16q21	Hs.295137	33	protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization
221931_s_at	-0.773	8.078	-5.789	3.382e-05	0.017	2.538	SEH1L	SEH1-like (S. cerevisiae)	18	12937982	AV701173	81929	18p11.21	Hs.301048	9	kinetochore nucleus nuclear pore organization mitotic metaphase plate congression protein transport Nup107-160 complex Nup107-160 complex mRNA transport attachment of spindle microtubules to kinetochore during mitosis intracellular protein transmembrane transport
201132_at	-0.736	8.987	-5.773	3.481e-05	0.017	2.512	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	X	100549846	NM_019597	3188	Xq22	Hs.632828	17	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm cytoskeleton heterogeneous nuclear ribonucleoprotein complex
227198_at	2.770	4.681	5.772	3.490e-05	0.017	2.509	AFF3	AF4/FMR2 family, member 3	2	-99530147, -99530147	AW085505	3899	2q11.2-q12	Hs.444414	16	DNA binding nucleus multicellular organismal development regulation of transcription
219109_at	0.978	6.414	5.760	3.567e-05	0.017	2.489	SPAG16	sperm associated antigen 16	2	213857360, 213857360	NM_024532	79582	2q34	Hs.602792 Hs.715620	6	cytoplasm cilium flagellum cell projection organization
225719_s_at	0.500	7.148	5.751	3.627e-05	0.017	2.474	MRPL55	mitochondrial ribosomal protein L55	1	-226361002	BG497783	128308	1q42.13	Hs.63236	11	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation
60471_at	0.598	5.612	5.747	3.653e-05	0.017	2.468	RIN3	Ras and Rab interactor 3	14	92049877	AA625133	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
200993_at	-0.615	10.084	-5.740	3.703e-05	0.017	2.455	IPO7	importin 7	11	9362744	AA939270	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
212586_at	-0.867	9.942	-5.737	3.725e-05	0.017	2.450	CAST	calpastatin	5	96023696, 96064251, 96104999	AA195244	831	5q15	Hs.436186	60	protein binding calcium-dependent cysteine-type endopeptidase inhibitor activity
213166_x_at	0.894	8.455	5.733	3.748e-05	0.017	2.444	FAM128A	family with sequence similarity 128, member A	2	-131958002	BG332462	653784	2q21.1	Hs.655067	2
213844_at	0.660	6.527	5.724	3.812e-05	0.017	2.429	HOXA5	homeobox A5	7	-27147520	NM_019102	3202	7p15-p14	Hs.655218	32	transcription factor activity nucleus regulation of transcription, DNA-dependent pattern specification process anterior/posterior pattern formation lung development thyroid gland development multicellular organism growth sequence-specific DNA binding embryonic skeletal system morphogenesis
228084_at	0.820	7.162	5.720	3.843e-05	0.017	2.421	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	AI767751	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
1569076_a_at	0.629	3.324	5.711	3.910e-05	0.017	2.406	ZNF836	zinc finger protein 836	19	-57349936	BE791720	162962	19q13.41	Hs.631584	1	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218128_at	-1.000	5.937	-5.689	4.072e-05	0.017	2.368	NFYB	nuclear transcription factor Y, beta	12	-103034987	AU151875	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
240744_at	0.846	5.173	5.688	4.081e-05	0.017	2.366	CPA5	carboxypeptidase A5	7	129771865, 129771865	AW184014	93979	7q32	Hs.567642	9	metallocarboxypeptidase activity extracellular region proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
224931_at	-0.601	7.334	-5.683	4.119e-05	0.017	2.358	SLC41A3	solute carrier family 41, member 3	3	-127207889, -127207889	AK021925	54946	3q21.2-q21.3	Hs.573007	5	plasma membrane cation transport cation transmembrane transporter activity integral to membrane
216733_s_at	-2.181	8.037	-5.681	4.130e-05	0.017	2.356	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	X86401	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
239084_at	-0.591	4.907	-5.680	4.138e-05	0.017	2.354	SNAP29	synaptosomal-associated protein, 29kDa	22	19543291	BE896490	9342	22q11.21	Hs.108002 Hs.701035	19	SNAP receptor activity cytoplasm plasma membrane exocytosis vesicle targeting membrane fusion protein transport synaptosome cell junction synapse	SNARE interactions in vesicular transport
1570025_at	-0.804	5.639	-5.664	4.262e-05	0.018	2.327	TACC2	transforming, acidic coiled-coil containing protein 2	10	123738678, 123913094	BC010219	10579	10q26	Hs.501252 Hs.713875	18	protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding
220235_s_at	-1.156	6.973	-5.658	4.312e-05	0.018	2.316	C1orf103	chromosome 1 open reading frame 103	1	-111291334	NM_018372	55791	1p13.3	Hs.25245	7	protein binding
213564_x_at	1.635	11.752	5.651	4.371e-05	0.018	2.304	LDHB	lactate dehydrogenase B	12	-21679542	BE042354	3945	12p12.2-p12.1	Hs.446149	27	L-lactate dehydrogenase activity binding cytoplasm oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
239035_at	0.475	6.290	5.638	4.478e-05	0.018	2.282	MTHFR	5,10-methylenetetrahydrofolate reductase (NADPH)	1	-11768373	AL138431	4524	1p36.3	Hs.214142	1776	methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction	One carbon pool by folate Methane metabolism Metabolic pathways
230405_at	0.507	7.327	5.638	4.480e-05	0.018	2.281	C5orf56	chromosome 5 open reading frame 56	5	131774571	AI143416	441108	5q31.1	Hs.658288	1
229178_at	0.605	4.428	5.636	4.497e-05	0.018	2.278	PRTG	protogenin homolog (Gallus gallus)	15	-53691041	AV699825	283659	15q21.3	Hs.130957	4	multicellular organismal development membrane integral to membrane
224435_at	0.846	8.214	5.611	4.708e-05	0.019	2.236	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	BC005871	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
224819_at	0.706	6.667	5.605	4.762e-05	0.019	2.225	TCEAL8	transcription elongation factor A (SII)-like 8	X	-102394578	AI743979	90843	Xq22.1	Hs.389734	4	nucleus regulation of transcription
219629_at	0.690	5.097	5.589	4.907e-05	0.019	2.198	FAM118A	family with sequence similarity 118, member A	22	44083744, 44084448	NM_017911	55007	22q13	Hs.265018	6	membrane integral to membrane
242056_at	0.674	7.261	5.585	4.950e-05	0.019	2.190	TRIM45	tripartite motif-containing 45	1	-117455199	AI793200	80263	1p13.1	Hs.301526	8	protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding
227337_at	-1.272	7.241	-5.581	4.981e-05	0.019	2.184	ANKRD37	ankyrin repeat domain 37	4	186554833	AA886870	353322	4q35.1	Hs.508154	4	nucleus cytoplasm
204999_s_at	2.290	5.575	5.577	5.019e-05	0.019	2.177	ATF5	activating transcription factor 5	19	55123785	BC005174	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
209780_at	-1.770	9.763	-5.576	5.031e-05	0.019	2.175	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AL136883	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
207076_s_at	1.812	7.831	5.576	5.034e-05	0.019	2.175	ASS1	argininosuccinate synthetase 1	9	132309914	NM_000050	445	9q34.1	Hs.160786	40	urea cycle nucleotide binding argininosuccinate synthase activity protein binding ATP binding cytoplasm arginine biosynthetic process cellular amino acid biosynthetic process ligase activity	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Metabolic pathways
206996_x_at	-0.511	9.524	-5.573	5.058e-05	0.019	2.170	CACNB1	calcium channel, voltage-dependent, beta 1 subunit	17	-34586914, -34583234	NM_000723	782	17q21-q22	Hs.635	18	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212427_at	-1.179	7.057	-5.567	5.119e-05	0.019	2.159	KIAA0368	KIAA0368	9	-113162793	AB002366	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
229770_at	0.828	6.353	5.536	5.421e-05	0.020	2.107	GLT1D1	glycosyltransferase 1 domain containing 1	12	127904033	AI041543	144423	12q24.33	Hs.655668	6	extracellular region biosynthetic process transferase activity, transferring glycosyl groups
204186_s_at	-0.930	7.957	-5.533	5.460e-05	0.020	2.100	PPID	peptidylprolyl isomerase D	4	-159849728	AI014573	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
224352_s_at	-0.771	11.148	-5.526	5.530e-05	0.020	2.088	CFL2	cofilin 2 (muscle)	14	-34249338, -34249338, -34249338	AF134802	1073	14q12	Hs.180141	20	actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
212551_at	-0.722	11.501	-5.513	5.661e-05	0.020	2.067	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6	17501714	NM_006366	10486	6p22.3	Hs.132902	7	actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity
218729_at	0.938	6.757	5.489	5.931e-05	0.021	2.024	LXN	latexin	3	-159866896	NM_020169	56925	3q25.32	Hs.478067	5	enzyme inhibitor activity protein binding cytoplasm metalloendopeptidase inhibitor activity detection of temperature stimulus involved in sensory perception of pain
237515_at	-2.052	6.341	-5.465	6.207e-05	0.022	1.983	TMEM56	transmembrane protein 56	1	95355481	AA054642	148534	1p21.3	Hs.483512	3	molecular_function cellular_component biological_process membrane integral to membrane
204998_s_at	2.300	6.902	5.461	6.253e-05	0.022	1.976	ATF5	activating transcription factor 5	19	55123785	NM_012068	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
214788_x_at	-1.824	7.439	-5.460	6.265e-05	0.022	1.974	DDN	dendrin	12	-47675199	AA731713	23109	12q13.12	Hs.591044	5	nucleus cytoplasm endoplasmic reticulum plasma membrane dendrite cell projection perikaryon
235721_at	0.460	6.811	5.459	6.271e-05	0.022	1.973	DTX3	deltex homolog 3 (Drosophila)	12	56284870	N62126	196403	12q13.3	Hs.32374	6	protein binding cytoplasm Notch signaling pathway zinc ion binding metal ion binding	Notch signaling pathway
201591_s_at	0.499	7.508	5.457	6.304e-05	0.022	1.968	NISCH	nischarin	3	52464563	NM_007184	11188	3p21.1	Hs.435290	16	receptor activity integrin binding protein binding membrane fraction cytoplasm early endosome cytosol plasma membrane glucose metabolic process apoptosis cell communication regulation of blood pressure amine receptor activity Rac protein signal transduction actin cytoskeleton organization negative regulation of cell migration regulation of synaptic transmission, GABAergic phosphoinositide binding norepinephrine secretion recycling endosome
206847_s_at	0.998	7.004	5.441	6.492e-05	0.022	1.942	HOXA7	homeobox A7	7	-27159862	AF026397	3204	7p15-p14	Hs.660918	24	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding negative regulation of keratinocyte differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
226748_at	-1.206	8.208	-5.438	6.534e-05	0.022	1.936	LYSMD2	LysM, putative peptidoglycan-binding, domain containing 2	15	-49802553, -49802553	AI674731	256586	15q21.2	Hs.631693	3	cell wall macromolecule catabolic process
218164_at	0.747	7.072	5.425	6.695e-05	0.023	1.913	SPATA20	spermatogenesis associated 20	17	45979560	NM_022827	64847	17q21.33	Hs.103147	7	catalytic activity protein binding multicellular organismal development spermatogenesis cell differentiation
212554_at	-0.596	11.653	-5.414	6.833e-05	0.023	1.894	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)	6	17501714	N90755	10486	6p22.3	Hs.132902	7	actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity
227865_at	0.629	5.673	5.407	6.922e-05	0.023	1.883	C9orf103	chromosome 9 open reading frame 103	9	85427785	BF111242	414328	9q21-q22	Hs.530261	1	nucleotide binding molecular_function shikimate kinase activity ATP binding cellular_component carbohydrate metabolic process biological_process transferase activity gluconokinase activity
209439_s_at	0.616	6.957	5.407	6.927e-05	0.023	1.882	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	D38616	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
229809_at	-0.720	5.722	-5.406	6.941e-05	0.023	1.880	POU6F1	POU class 6 homeobox 1	12	-49866986, -49866986	AW445212	5463	12q13.13	Hs.555886	10	transcription factor activity nucleus regulation of transcription, DNA-dependent brain development heart development muscle organ development sequence-specific DNA binding
218676_s_at	-0.611	6.714	-5.390	7.153e-05	0.023	1.852	PCTP	phosphatidylcholine transfer protein	17	51183354	NM_021213	58488	17q21-q24	Hs.285218	9	cytoplasm cytosol cytosol lipid binding phosphatidylcholine transmembrane transporter activity phosphatidylcholine transmembrane transporter activity phospholipid transport phosphatidylcholine binding
228376_at	0.808	5.826	5.389	7.170e-05	0.023	1.850	GGTA1	glycoprotein, alpha-galactosyltransferase 1	9	-123257139	AI972498	2681	9q33.2-q34.11	Hs.97469	6	Golgi apparatus carbohydrate metabolic process membrane integral to membrane transferase activity, transferring hexosyl groups
235635_at	-0.639	5.358	-5.388	7.176e-05	0.023	1.849	ARHGAP5	Rho GTPase activating protein 5	14	31616245	N50119	394	14q12	Hs.592313	19	GTPase activity GTPase activator activity Rho GTPase activator activity GTP binding intracellular cytoplasm cell adhesion signal transduction small GTPase mediated signal transduction Rho protein signal transduction membrane SH2 domain binding	Focal adhesion Leukocyte transendothelial migration
218843_at	0.966	6.142	5.387	7.194e-05	0.023	1.847	FNDC4	fibronectin type III domain containing 4	2	-27568254	NM_022823	64838	2p23.3	Hs.27836 Hs.718524	6	membrane integral to membrane
204784_s_at	-1.891	8.892	-5.375	7.361e-05	0.023	1.826	MLF1	myeloid leukemia factor 1	3	159771646	NM_022443	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
208029_s_at	-1.353	8.976	-5.372	7.401e-05	0.023	1.821	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	NM_018407	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
224444_s_at	0.907	5.346	5.369	7.452e-05	0.023	1.815	C1orf97	chromosome 1 open reading frame 97	1	209622719	BC005997	84791	1q32.3	Hs.523932	4
242915_at	1.275	3.739	5.365	7.508e-05	0.023	1.808	ZNF682	zinc finger protein 682	19	-19976226, -19976226	AA603590	91120	19p12	Hs.306298	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213599_at	-1.198	6.367	-5.361	7.567e-05	0.023	1.801	OIP5	Opa interacting protein 5	15	-39388757	BE045993	11339	15q15.1	Hs.661645	6	chromosome, centromeric region chromatin protein binding cellular_component nucleus cell cycle mitosis cell communication chromocenter Cajal body cell division
201832_s_at	-0.685	9.929	-5.346	7.776e-05	0.024	1.776	USO1	USO1 homolog, vesicle docking protein (yeast)	4	76868852	NM_003715	8615	4q21.1	Hs.292689	34	Golgi membrane protein binding cytoplasm microsome Golgi apparatus cytosol intracellular protein transport protein transporter activity membrane vesicle-mediated transport vesicle fusion with Golgi apparatus perinuclear region of cytoplasm
226083_at	-1.394	7.027	-5.339	7.885e-05	0.024	1.763	TMEM70	transmembrane protein 70	8	75050983	AA886902	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
210202_s_at	-0.889	10.258	-5.333	7.971e-05	0.024	1.753	BIN1	bridging integrator 1	2	-127522077, -127522076	U87558	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
205437_at	0.832	5.822	5.320	8.178e-05	0.024	1.729	ZNF211	zinc finger protein 211	19	62836346	NM_006385	10520	19q13.4	Hs.590977	4	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222742_s_at	0.577	8.412	5.316	8.240e-05	0.024	1.722	RABL5	RAB, member RAS oncogene family-like 5	7	-100743368	AW026449	64792	7q22.1	Hs.389104	4	nucleotide binding GTP binding
205951_at	-2.946	11.141	-5.314	8.267e-05	0.024	1.719	MYH1	myosin, heavy chain 1, skeletal muscle, adult	17	-10336348	NM_005963	4619	17p13.1	Hs.689619	30	nucleotide binding motor activity actin binding calmodulin binding ATP binding nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction myosin complex myofibril A band	Tight junction
232986_at	0.583	3.869	5.314	8.276e-05	0.024	1.718	ZNF233	zinc finger protein 233	19	49455915	AC074331	353355	19q13.31	Hs.466891	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210201_x_at	-0.710	10.934	-5.311	8.324e-05	0.024	1.713	BIN1	bridging integrator 1	2	-127522077, -127522076	AF001383	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
203264_s_at	0.654	5.026	5.310	8.329e-05	0.024	1.713	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9	X	-62771572	NM_015185	23229	Xq11.1	Hs.54697	10	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm regulation of Rho protein signal transduction
201297_s_at	-0.901	5.545	-5.305	8.409e-05	0.024	1.704	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	2	-74236718	AK023321	55233	2p13.1	Hs.196437	12	protein binding zinc ion binding metal ion binding
214439_x_at	-0.702	10.906	-5.304	8.437e-05	0.024	1.701	BIN1	bridging integrator 1	2	-127522077, -127522076	AF043899	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
1553971_a_at	-1.303	6.969	-5.297	8.546e-05	0.024	1.689	GATS	GATS, stromal antigen 3 opposite strand	7	-99644496, -99636215	AL831967	352954	7q22.1	Hs.556063 Hs.718406	4
235301_at	0.792	5.912	5.292	8.637e-05	0.024	1.679	KIAA1324L	KIAA1324-like	7	-86347173, -86347173	AI797353	222223	7q21.12	Hs.208093	3	G-protein coupled receptor activity protein binding G-protein coupled receptor protein signaling pathway membrane integral to membrane
209605_at	0.912	8.090	5.283	8.788e-05	0.024	1.663	TST	thiosulfate sulfurtransferase (rhodanese)	22	-35736851	D87292	7263	22q13.1	Hs.474783	25	thiosulfate sulfurtransferase activity mitochondrion mitochondrial matrix plasma membrane sulfate transport cyanate catabolic process transferase activity
228863_at	0.838	4.329	5.275	8.921e-05	0.024	1.649	PCDH17	protocadherin 17	13	57103789	N69091	27253	13q21.1	Hs.106511	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
206030_at	0.815	8.060	5.273	8.945e-05	0.024	1.647	ASPA	aspartoacylase (Canavan disease)	17	3324153, 3326045	NM_000049	443	17pter-p13	Hs.171142	27	aminoacylase activity nucleus cytoplasm aspartate catabolic process metabolic process zinc ion binding hydrolase activity, acting on ester bonds aspartoacylase activity metal ion binding	Alanine, aspartate and glutamate metabolism Histidine metabolism
232124_at	0.575	3.430	5.272	8.969e-05	0.024	1.644	LOC729085	hypothetical protein LOC729085	3	42995762	AL117530	729085	3p22.1	Hs.146346	2
208754_s_at	-0.852	7.540	-5.263	9.127e-05	0.024	1.628	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AL162068	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
203570_at	1.169	4.863	5.250	9.351e-05	0.025	1.606	LOXL1	lysyl oxidase-like 1	15	72005841	NM_005576	4016	15q22 15q24-q25	Hs.65436	48	copper ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space oxidoreductase activity oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor protein amino acid deamination metal ion binding oxidation reduction
225010_at	-0.648	7.666	-5.246	9.427e-05	0.025	1.599	CCDC6	coiled-coil domain containing 6	10	-61218526	AK024913	8030	10q21	Hs.591360	20	structural constituent of cytoskeleton protein binding cellular_component cytoplasm cytoskeleton biological_process SH3 domain binding	Pathways in cancer Thyroid cancer
214890_s_at	1.480	5.468	5.236	9.602e-05	0.025	1.582	FAM149A	family with sequence similarity 149, member A	4	187302988, 187307320	AL080065	25854	4q35.1	Hs.357025	3
224477_s_at	0.525	6.507	5.231	9.703e-05	0.025	1.572	NUDT16L1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1	16	4683716	BC006223	84309	16p13.3	Hs.592084	5	cytoplasm
201397_at	0.434	6.069	5.221	9.888e-05	0.025	1.555	PHGDH	phosphoglycerate dehydrogenase	1	120055941	NM_006623	26227	1p12	Hs.487296	18	phosphoglycerate dehydrogenase activity L-serine biosynthetic process brain development cellular amino acid biosynthetic process electron carrier activity oxidoreductase activity cofactor binding NAD or NADH binding oxidation reduction	Glycine, serine and threonine metabolism Metabolic pathways
205589_at	0.632	12.188	5.220	9.907e-05	0.025	1.553	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	3	-46874360	NM_000258	4634	3p21.3-p21.2	Hs.517939	27	regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex regulation of striated muscle contraction structural constituent of muscle myosin complex A band I band myosin II heavy chain binding positive regulation of ATPase activity ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
210967_x_at	-0.479	9.549	-5.220	9.919e-05	0.025	1.552	CACNB1	calcium channel, voltage-dependent, beta 1 subunit	17	-34586914, -34583234	M92301	782	17q21-q22	Hs.635	18	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
206869_at	0.511	5.324	5.212	1.006e-04	0.026	1.538	CHAD	chondroadherin	17	-45896851	NM_001267	1101	17q21.33	Hs.97220	6	regulation of cell growth extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix	Focal adhesion ECM-receptor interaction
210807_s_at	0.798	4.907	5.210	1.010e-04	0.026	1.535	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	AF049608	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
204783_at	-2.201	7.532	-5.205	1.021e-04	0.026	1.525	MLF1	myeloid leukemia factor 1	3	159771646	AI911434	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
208767_s_at	-1.787	9.437	-5.200	1.031e-04	0.026	1.516	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	AW149681	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
224906_at	-0.668	8.706	-5.198	1.034e-04	0.026	1.514	ANO6	anoctamin 6	12	43896036, 43896036, 43896142, 43972732	AL041280	196527	12q12	Hs.696326	6	ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex
212689_s_at	-1.040	6.775	-5.195	1.040e-04	0.026	1.509	KDM3A	lysine (K)-specific demethylase 3A	2	86521781, 86522094	AA524505	55818	2p11.2	Hs.557425	11	iron ion binding nucleus cytoplasm spermatogenesis zinc ion binding hormone-mediated signaling oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cell differentiation androgen receptor signaling pathway histone H3-K9 demethylation positive regulation of transcription formaldehyde biosynthetic process metal ion binding androgen receptor binding oxidation reduction
217781_s_at	-0.805	11.287	-5.194	1.042e-04	0.026	1.507	ZFP106	zinc finger protein 106 homolog (mouse)	15	-40492312	NM_022473	64397	15q15.1	Hs.511143	9	opioid peptide activity intracellular membrane fraction nucleus nucleolus cytosol zinc ion binding insulin receptor signaling pathway SH3 domain binding metal ion binding
204629_at	0.586	6.712	5.193	1.043e-04	0.026	1.505	PARVB	parvin, beta	22	42726505, 42751500	NM_013327	29780	22q13.2-q13.33	Hs.475074	18	actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion cell junction	Focal adhesion
227239_at	-1.183	8.467	-5.190	1.051e-04	0.026	1.499	FAM126A	family with sequence similarity 126, member A	7	-22947402	AV734839	84668	7p15.3	Hs.85603	9	signal transducer activity cellular_component cytoplasm biological_process membrane
222919_at	-0.748	12.085	-5.190	1.051e-04	0.026	1.498	TRDN	triadin	6	-123579181	AA192306	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
219256_s_at	0.627	4.260	5.188	1.055e-04	0.026	1.495	SH3TC1	SH3 domain and tetratricopeptide repeats 1	4	8251959	NM_018986	54436	4p16.1	Hs.479116	5	binding cellular_component biological_process
229177_at	0.520	5.551	5.186	1.058e-04	0.026	1.492	C16orf89	chromosome 16 open reading frame 89	16	-5034123	AI823572	146556	16p13.3	Hs.11782	4	extracellular region
202003_s_at	0.874	10.017	5.184	1.063e-04	0.026	1.488	ACAA2	acetyl-Coenzyme A acyltransferase 2	18	-45563871	NM_006111	10449	18q21.1	Hs.200136	10	acetyl-CoA C-acyltransferase activity mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process cholesterol biosynthetic process metabolic process acyltransferase activity transferase activity	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Metabolic pathways
209190_s_at	-0.490	7.858	-5.177	1.076e-04	0.026	1.476	DIAPH1	diaphanous homolog 1 (Drosophila)	5	-140874771	AF051782	1729	5q31	Hs.529451	33	actin binding receptor binding cytoplasm cytoskeleton plasma membrane sensory perception of sound cellular component organization Rho GTPase binding actin cytoskeleton organization ruffle membrane cell projection	Focal adhesion Regulation of actin cytoskeleton
218858_at	-1.001	9.627	-5.172	1.087e-04	0.026	1.467	DEPDC6	DEP domain containing 6	8	120955080	NM_022783	64798	8q24.12	Hs.112981	11	protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size
238613_at	-0.722	9.818	-5.170	1.092e-04	0.026	1.463	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AI475164	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
221027_s_at	0.846	8.404	5.167	1.097e-04	0.026	1.459	PLA2G12A	phospholipase A2, group XIIA	4	-110850594	NM_030821	81579	4q25	Hs.389452	10	calcium ion binding extracellular region intracellular cytoplasm endoplasmic reticulum Golgi apparatus phospholipid metabolic process biological_process lipid catabolic process hydrolase activity calcium-dependent phospholipase A2 activity	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
224820_at	1.013	9.256	5.163	1.106e-04	0.026	1.451	FAM36A	family with sequence similarity 36, member A	1	243065261	AA831192	116228	1q44	Hs.715571	5	membrane integral to membrane
204875_s_at	0.422	2.407	5.149	1.137e-04	0.026	1.426	GMDS	GDP-mannose 4,6-dehydratase	6	-1569039	NM_001500	2762	6p25	Hs.144496 Hs.660919	11	binding intracellular cytoplasm carbohydrate metabolic process leukocyte adhesion GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process cellular metabolic process coenzyme binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
232473_at	0.636	4.405	5.145	1.145e-04	0.027	1.419	PRPF18	PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae)	10	13668944	AU144329	8559	10p13	Hs.161181	6	nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck
1555310_a_at	0.561	5.885	5.136	1.165e-04	0.027	1.404	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	15	38296920, 38319326	BC035596	56924	15q14	Hs.513645	13	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
218546_at	0.806	6.346	5.133	1.172e-04	0.027	1.398	C1orf115	chromosome 1 open reading frame 115	1	218930250	NM_024709	79762	1q41	Hs.519839	6	membrane integral to membrane
239203_at	-1.465	8.595	-5.132	1.176e-04	0.027	1.395	C7orf53	chromosome 7 open reading frame 53	7	111908143, 111908301	AW014728	286006	7q31.1	Hs.396189	5	membrane integral to membrane
202931_x_at	-0.674	10.850	-5.127	1.187e-04	0.027	1.386	BIN1	bridging integrator 1	2	-127522077, -127522076	NM_004305	274	2q14	Hs.193163	69	protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms
208998_at	1.314	9.646	5.126	1.188e-04	0.027	1.385	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	11	-73363363	U94592	7351	11q13	Hs.80658	153	response to superoxide binding mitochondrion mitochondrial inner membrane transport mitochondrial transport proton transport membrane integral to membrane
201223_s_at	-0.560	9.235	-5.122	1.197e-04	0.027	1.378	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	NM_002874	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
204185_x_at	-0.750	9.597	-5.121	1.201e-04	0.027	1.375	PPID	peptidylprolyl isomerase D	4	-159849728	NM_005038	5481	4q31.3	Hs.581725	25	peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding	Calcium signaling pathway Parkinson's disease Huntington's disease
228618_at	0.523	5.843	5.119	1.204e-04	0.027	1.373	PEAR1	platelet endothelial aggregation receptor 1	1	155130146	AL040178	375033	1q23.1	Hs.142003 Hs.715070	3	plasma membrane integral to membrane
211063_s_at	-0.491	8.090	-5.115	1.214e-04	0.027	1.365	NCK1	NCK adaptor protein 1	3	138063762	BC006403	4690	3q21	Hs.477693	110	receptor binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal complex assembly cytoskeletal adaptor activity vesicle membrane cell migration protein domain specific binding lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
225876_at	0.814	5.801	5.112	1.222e-04	0.027	1.359	NIPAL3	NIPA-like domain containing 3	1	24614831	T84558	57185	1p36.12-p35.1	Hs.523442	6	membrane integral to membrane
225466_at	-0.607	7.832	-5.094	1.266e-04	0.028	1.327	PATL1	protein associated with topoisomerase II homolog 1 (yeast)	11	-59160767	BG291961	219988	11q12.1	Hs.591960	8	cytoplasmic mRNA processing body cytoplasm	RNA degradation
233899_x_at	-0.572	4.735	-5.093	1.268e-04	0.028	1.325	ZBTB10	zinc finger and BTB domain containing 10	8	81561002	AK024296	65986	8q13-q21.1	Hs.591868	4	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
209806_at	0.830	6.025	5.078	1.304e-04	0.028	1.299	HIST1H2BK	histone cluster 1, H2bk	6	-27214051	BC000893	85236	6p21.33	Hs.437275 Hs.689116	26	nucleosome DNA binding nucleus chromosome nucleosome assembly defense response to bacterium	Systemic lupus erythematosus
213473_at	-0.519	6.935	-5.070	1.324e-04	0.028	1.285	BRAP	BRCA1 associated protein	12	-110564332	AL042733	8315	12q24	Hs.530940	12	ubiquitin-protein ligase activity cytoplasm zinc ion binding negative regulation of signal transduction ligase activity modification-dependent protein catabolic process identical protein binding metal ion binding
202577_s_at	-0.663	6.353	-5.070	1.326e-04	0.028	1.284	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A	16	68938324	BC005162	55308	16q22.1	Hs.656037	5	nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport
1568900_a_at	0.536	3.053	5.069	1.328e-04	0.028	1.283	ZNF568	zinc finger protein 568	19	42099073	BC031218	374900	19q13.12	Hs.404220	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235753_at	0.798	7.886	5.057	1.358e-04	0.029	1.262	HOXA7	homeobox A7	7	-27159862	AI492051	3204	7p15-p14	Hs.660918	24	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding negative regulation of keratinocyte differentiation positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis
226028_at	0.614	7.036	5.040	1.406e-04	0.030	1.230	ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	11	-124259324	AA156022	54538	11q24.2	Hs.524121	19	angiogenesis receptor activity multicellular organismal development integral to membrane cell differentiation regulation of cell migration
204422_s_at	1.391	3.435	5.039	1.409e-04	0.030	1.228	FGF2	fibroblast growth factor 2 (basic)	4	123967312	NM_002006	2247	4q26-q27	Hs.284244	320	activation of MAPKK activity activation of MAPK activity induction of an organ positive regulation of protein amino acid phosphorylation protein binding extracellular region extracellular region extracellular space apoptosis chemotaxis signal transduction Ras protein signal transduction multicellular organismal development nervous system development growth factor activity heparin binding negative regulation of cell proliferation fibroblast growth factor receptor signaling pathway organ morphogenesis glial cell differentiation positive regulation of granule cell precursor proliferation lung development positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration positive regulation of cell differentiation positive regulation of angiogenesis regulation of retinal cell programmed cell death positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
239750_x_at	-0.735	4.278	-5.036	1.416e-04	0.030	1.223	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	18	9903954	AI671488	9218	18p11.22	Hs.699980	18	signal transducer activity structural molecule activity protein binding membrane fraction endoplasmic reticulum microtubule plasma membrane tight junction membrane fusion integral to membrane vesicle positive regulation of I-kappaB kinase/NF-kappaB cascade protein heterodimerization activity perinuclear region of cytoplasm	Tight junction
205011_at	0.569	6.303	5.027	1.441e-04	0.030	1.208	VWA5A	von Willebrand factor A domain containing 5A	11	123491320, 123491320	NM_014622	4013	11q23	Hs.152944	5
212539_at	-0.606	7.260	-5.026	1.443e-04	0.030	1.206	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	AI422099	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
213787_s_at	0.625	6.315	5.022	1.454e-04	0.030	1.199	EBP	emopamil binding protein (sterol isomerase)	X	48265107	AV702405	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
212150_at	-0.849	8.492	-5.022	1.456e-04	0.030	1.198	EFR3A	EFR3 homolog A (S. cerevisiae)	8	132985540	AA805651	23167	8q24.22	Hs.204564	4	binding plasma membrane
217551_at	0.633	3.983	5.018	1.466e-04	0.030	1.191	LOC441453	similar to olfactory receptor, family 7, subfamily A, member 17	11		AA719797	441453	11p15.1	Hs.523504	1
228346_at	0.910	6.290	5.015	1.477e-04	0.030	1.185	ZNF844	zinc finger protein 844	19	12036545	H47630	284391	19p13.2	Hs.646391	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202077_at	0.472	12.059	5.014	1.478e-04	0.030	1.184	NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	16	-23499835	NM_005003	4706	16p12.2	Hs.189716	14	acyl carrier activity fatty acid binding calcium ion binding mitochondrion mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone fatty acid biosynthetic process transport NADH dehydrogenase (ubiquinone) activity electron transport chain phosphopantetheine binding mitochondrial membrane mitochondrial membrane cofactor binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
227321_at	-1.081	7.016	-5.012	1.483e-04	0.030	1.181	GATS	GATS, stromal antigen 3 opposite strand	7	-99644496, -99636215	D52585	352954	7q22.1	Hs.556063 Hs.718406	4
223339_at	0.664	7.497	5.008	1.497e-04	0.030	1.172	ATPIF1	ATPase inhibitory factor 1	1	28435197	BC001867	93974		Hs.590908	13	angiogenesis negative regulation of endothelial cell proliferation calmodulin binding mitochondrion mitochondrion mitochondrial proton-transporting ATP synthase complex generation of precursor metabolites and energy cell surface ATPase inhibitor activity ATPase inhibitor activity protein homodimerization activity angiostatin binding negative regulation of nucleotide metabolic process ATPase binding ATPase binding protein homotetramerization negative regulation of hydrolase activity negative regulation of hydrolase activity
202847_at	1.312	4.676	5.005	1.505e-04	0.030	1.167	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	14	23633322, 23633322	NM_004563	5106	14q11.2	Hs.75812	9	phosphoenolpyruvate carboxykinase (GTP) activity GTP binding mitochondrion gluconeogenesis lyase activity purine nucleotide binding manganese ion binding metal ion binding	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways PPAR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway
201667_at	0.851	7.602	5.002	1.513e-04	0.030	1.162	GJA1	gap junction protein, alpha 1, 43kDa	6	121798443	NM_000165	2697	6q21-q23.2	Hs.74471	181	signal transducer activity protein binding cytoplasm mitochondrial outer membrane lysosome early endosome multivesicular body endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane integral to plasma membrane fascia adherens connexon complex apoptosis muscle contraction cell-cell signaling heart development negative regulation of cell proliferation response to pH vascular transport ion transmembrane transporter activity ATP transport gap junction assembly SH3 domain binding transmembrane transporter activity cell junction PDZ domain binding Golgi-associated vesicle membrane positive regulation of I-kappaB kinase/NF-kappaB cascade membrane raft positive regulation of protein catabolic process neuron projection morphogenesis protein oligomerization regulation of calcium ion transport	Gap junction Arrhythmogenic right ventricular cardiomyopathy (ARVC)
219505_at	0.879	6.139	5.001	1.517e-04	0.030	1.160	CECR1	cat eye syndrome chromosome region, candidate 1	22	-16040193, -16040191	NM_017424	51816	22q11.2	Hs.170310	10	extracellular region extracellular space Golgi apparatus multicellular organismal development growth factor activity purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity
213057_at	0.569	6.568	4.999	1.521e-04	0.030	1.157	ATPAF2	ATP synthase mitochondrial F1 complex assembly factor 2	17	-17862058	AW118608	91647	17p11.2	Hs.528889	11	protein binding mitochondrion nuclear speck proton-transporting ATP synthase complex assembly
229287_at	-0.604	7.423	-4.995	1.533e-04	0.030	1.150	PCNX	pecanex homolog (Drosophila)	14	70443874	BE326214	22990	14q24.2	Hs.446559	10	membrane integral to membrane
218211_s_at	0.720	7.239	4.988	1.554e-04	0.031	1.137	MLPH	melanophilin	2	238060616	NM_024101	79083	2q37.3	Hs.102406	23	protein binding cytoplasm intracellular protein transport zinc ion binding Rab GTPase binding metal ion binding
217873_at	-1.066	9.662	-4.986	1.562e-04	0.031	1.133	CAB39	calcium binding protein 39	2	231285800, 231286506	NM_016289	51719	2q37.1	Hs.632536	14	protein binding cytoplasm	mTOR signaling pathway
210652_s_at	0.990	4.608	4.978	1.586e-04	0.031	1.118	TTC39A	tetratricopeptide repeat domain 39A	1	-51525518, -51525518	BC004399	22996	1p32.3	Hs.112949	3	binding cellular_component biological_process
219604_s_at	0.402	4.535	4.975	1.595e-04	0.031	1.113	ZNF3	zinc finger protein 3	7	-99505529, -99499588	NM_017715	7551	7q22.1	Hs.435302	10	transcription factor activity intracellular nucleus nucleus nucleolus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding cell differentiation identical protein binding leukocyte activation metal ion binding
204608_at	0.718	5.290	4.974	1.599e-04	0.031	1.111	ASL	argininosuccinate lyase	7	65178210, 65178268	NM_000048	435	7cen-q11.2	Hs.632015	19	urea cycle argininosuccinate metabolic process response to hypoxia kidney development liver development argininosuccinate lyase activity cytoplasm arginine catabolic process response to nutrient locomotory behavior cellular amino acid biosynthetic process post-embryonic development lyase activity ammonia assimilation cycle arginine biosynthetic process via ornithine response to peptide hormone stimulus response to steroid hormone stimulus response to glucocorticoid stimulus response to cAMP	Alanine, aspartate and glutamate metabolism Arginine and proline metabolism Metabolic pathways
214846_s_at	-1.021	7.757	-4.970	1.611e-04	0.031	1.104	ALPK3	alpha-kinase 3	15	83160914	AB037751	57538	15q25.2	Hs.459183	5	protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation multicellular organismal development heart development kinase activity transferase activity
207550_at	0.532	3.170	4.957	1.654e-04	0.032	1.080	MPL	myeloproliferative leukemia virus oncogene	1	43576061	NM_005373	4352	1p34	Hs.82906	85	cytokine receptor activity plasma membrane integral to plasma membrane cell surface receptor linked signal transduction cell proliferation	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
241233_x_at	0.410	7.465	4.947	1.685e-04	0.032	1.063	C21orf81	ankyrin repeat domain 20 family, member A3 pseudogene	21	-14237966	AI978581	391267	21q11.2	Hs.364456	2
206799_at	1.845	5.452	4.946	1.689e-04	0.032	1.060	SCGB1D2	secretoglobin, family 1D, member 2	11	61766299	NM_006551	10647	11q13	Hs.204096	9	binding extracellular region extracellular space
218176_at	0.425	6.626	4.946	1.690e-04	0.032	1.060	MAGEF1	melanoma antigen family F, 1	3	-185910848	NM_022149	64110	3q13	Hs.306123	4
213587_s_at	0.705	6.317	4.946	1.690e-04	0.032	1.060	ATP6V0E2	ATPase, H+ transporting V0 subunit e2	7	149200989, 149200989	AI884867	155066	7q36.1	Hs.556998 Hs.698060	5	ion transport vacuolar acidification hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport membrane integral to membrane cell growth hydrolase activity proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions	Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
225308_s_at	0.669	6.133	4.943	1.699e-04	0.032	1.055	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	2	159533391	AB051515	85461	2q24.2	Hs.61590	6	binding plasma membrane postsynaptic density cell junction synapse postsynaptic membrane
221505_at	-0.559	8.351	-4.941	1.706e-04	0.032	1.051	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	1	-148457341, -148457341	AW612574	81611	1q21.2	Hs.656466	14	protein binding nucleus cytoplasm cytoplasmic membrane-bounded vesicle phosphatase inhibitor activity
1554822_at	-1.585	5.931	-4.938	1.716e-04	0.032	1.046	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	BC022419	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
213035_at	-1.006	7.921	-4.931	1.741e-04	0.032	1.033	ANKRD28	ankyrin repeat domain 28	3	-15683747	AI081194	23243	3p25.1	Hs.335239	10	protein binding nucleus nucleoplasm
208669_s_at	-0.504	9.563	-4.928	1.751e-04	0.032	1.027	EID1	EP300 interacting inhibitor of differentiation 1	15	46957581	AF109873	23741	15q21.1-q21.2	Hs.255973 Hs.714048	12	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding cellular_component nucleus cytoplasm cell cycle specific transcriptional repressor activity cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of transcription
225812_at	0.804	6.637	4.924	1.762e-04	0.032	1.021	C6orf225	chromosome 6 open reading frame 225	6	112515366	N36759	619208	6q21	Hs.591340	1
200759_x_at	-0.600	11.280	-4.924	1.762e-04	0.032	1.021	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	NM_003204	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
227923_at	0.691	7.008	4.923	1.767e-04	0.032	1.019	SHANK3	SH3 and multiple ankyrin repeat domains 3	22	49459935	BF439330	85358	22q13.3	Hs.149035	21	MAPKKK cascade embryonic epithelial tube formation protein binding cytoplasm plasma membrane postsynaptic density SH3 domain binding cell junction synapse postsynaptic membrane
235595_at	0.502	6.625	4.922	1.772e-04	0.032	1.016	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	1	-154183253, -154183253	AW299534	9181	1q21-q22	Hs.655209	28	cell morphogenesis guanyl-nucleotide exchange factor activity intracellular cytoplasm Golgi apparatus spindle microtubule tight junction intracellular protein transport actin filament organization negative regulation of microtubule depolymerization cell cycle mitosis intracellular signaling cascade microtubule binding zinc ion binding diacylglycerol binding cell junction Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction regulation of cell proliferation metal ion binding Rac GTPase binding cell division	Pathogenic Escherichia coli infection - EHEC
206329_at	0.892	6.287	4.921	1.775e-04	0.032	1.015	EXTL1	exostoses (multiple)-like 1	1	26220857	NM_004455	2134	1p36.1	Hs.150956	11	skeletal system development protein binding endoplasmic reticulum membrane integral to membrane transferase activity, transferring hexosyl groups intrinsic to endoplasmic reticulum membrane glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Heparan sulfate biosynthesis Metabolic pathways
207551_s_at	-0.567	7.380	-4.918	1.784e-04	0.032	1.010	MSL3	male-specific lethal 3 homolog (Drosophila)	X	11686198, 11686198, 11687681	NM_006800	10943	Xp22.3	Hs.655288	6	chromatin chromatin binding transcription factor activity nucleus chromatin assembly or disassembly transcription from RNA polymerase II promoter multicellular organismal development chromatin modification regulation of transcription
1556839_s_at	0.785	4.206	4.916	1.791e-04	0.032	1.006	SPTBN5	spectrin, beta, non-erythrocytic 5	15	-39927635	AA515490	51332	15q21	Hs.709819	3	actin binding cytoplasm cytoskeleton spectrin membrane actin cytoskeleton organization actin filament capping
202041_s_at	0.595	8.116	4.914	1.797e-04	0.032	1.003	FIBP	fibroblast growth factor (acidic) intracellular binding protein	11	-65407786	NM_004214	9158	11q13.1	Hs.7768	10	protein binding membrane fraction nucleus mitochondrion fibroblast growth factor receptor signaling pathway membrane fibroblast growth factor binding
232183_at	-0.548	6.202	-4.911	1.810e-04	0.032	0.996	SERAC1	serine active site containing 1	6	-158450523	AA128978	84947	6q25.3	Hs.154706	6	binding membrane integral to membrane
219090_at	-1.496	7.810	-4.909	1.817e-04	0.032	0.993	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	20	19141289	NM_020689	57419	20p13	Hs.654790	2	calcium ion binding ion transport potassium ion transport sodium ion transport calcium ion transport calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral to membrane potassium ion binding sodium ion binding
206024_at	0.516	3.309	4.908	1.818e-04	0.032	0.992	HPD	4-hydroxyphenylpyruvate dioxygenase	12	-120761815	NM_002150	3242	12q24-qter	Hs.2899	11	4-hydroxyphenylpyruvate dioxygenase activity iron ion binding endoplasmic reticulum Golgi apparatus L-phenylalanine catabolic process tyrosine catabolic process aromatic amino acid family metabolic process oxidoreductase activity metal ion binding oxidation reduction	Ubiquinone and other terpenoid-quinone biosynthesis Tyrosine metabolism Phenylalanine metabolism Metabolic pathways
201935_s_at	-1.148	7.842	-4.905	1.829e-04	0.032	0.987	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	1	-21005560	AI768122	8672	1p36.12	Hs.467084	19	RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
208985_s_at	-0.867	9.651	-4.902	1.840e-04	0.032	0.981	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	BC002719	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
218082_s_at	-0.555	7.293	-4.900	1.850e-04	0.032	0.976	UBP1	upstream binding protein 1 (LBP-1a)	3	-33404831, -33404831	NM_014517	7342	3p22.3	Hs.643744	11	transcription factor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter negative regulation of transcription specific transcriptional repressor activity viral genome replication
229132_at	-0.602	4.767	-4.898	1.855e-04	0.032	0.974	MINA	MYC induced nuclear antigen	3	-99143350, -99143350	AI346432	84864	3q11.2	Hs.607776	15	nucleus nucleolus cytoplasm ribosome biogenesis
244741_s_at	1.654	6.388	4.895	1.865e-04	0.032	0.969	MGC9913	hypothetical protein MGC9913	19		BE855713	386759	19q13.43	Hs.23133	1
228902_at	-0.485	5.240	-4.890	1.885e-04	0.033	0.959	NUP214	nucleoporin 214kDa	9	132990801	AA516455	8021	9q34.1	Hs.654530	47	transporter activity protein binding nucleus nuclear pore cytosol protein export from nucleus protein transport mRNA transport intracellular protein transmembrane transport
224751_at	-0.739	8.277	-4.888	1.891e-04	0.033	0.956	PL-5283	PL-5283 protein	7	134997760	BE738276	647087	7q33	Hs.200022	3
226027_at	0.622	6.573	4.884	1.908e-04	0.033	0.948	C9orf119	chromosome 9 open reading frame 119	9	130078245	BG541668	375757	9q34.11	Hs.259594	1
205830_at	2.049	4.555	4.882	1.917e-04	0.033	0.944	CLGN	calmegin	4	-141529056	NM_004362	1047	4q28.3-q31.1	Hs.86368	11	calcium ion binding endoplasmic reticulum protein folding single fertilization membrane integral to membrane unfolded protein binding
242396_at	0.558	3.868	4.877	1.935e-04	0.033	0.935	LOC100132798	similar to hCG1774772	15		AA195408	100132798	15q26.2
217924_at	-0.583	6.187	-4.875	1.942e-04	0.033	0.931	C6orf106	chromosome 6 open reading frame 106	6	-34663047	AL523965	64771	6p21.31	Hs.643498	10
206175_x_at	0.533	4.863	4.870	1.961e-04	0.033	0.923	ZNF222	zinc finger protein 222	19	49221333	NM_013360	7673	19q13.2	Hs.279840	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201906_s_at	1.057	7.024	4.869	1.965e-04	0.033	0.921	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	NM_005808	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
228696_at	0.404	4.077	4.867	1.973e-04	0.033	0.917	SLC45A3	solute carrier family 45, member 3	1	-203893603	AA631143	85414	1q32.1	Hs.278695	9	transport membrane integral to membrane
227054_at	0.437	7.055	4.860	2.001e-04	0.033	0.904	N6AMT2	N-6 adenine-specific DNA methyltransferase 2 (putative)	13	-20201072	AI141584	221143	13q12.11	Hs.26674	3	nucleic acid binding methyltransferase activity transferase activity methylation
226238_at	0.671	8.022	4.859	2.004e-04	0.033	0.902	MCEE	methylmalonyl CoA epimerase	2	-71190313	AI934339	84693	2p13.3	Hs.94949	7	methylmalonyl-CoA epimerase activity mitochondrion isomerase activity L-methylmalonyl-CoA metabolic process	Valine, leucine and isoleucine degradation Propanoate metabolism Metabolic pathways
212995_x_at	0.653	8.794	4.857	2.013e-04	0.033	0.898	FAM128B	family with sequence similarity 128, member B	2	130656172	BG255188	80097	2q21.1	Hs.469925 Hs.516450	2
225381_at	0.958	5.988	4.852	2.032e-04	0.033	0.890	LOC399959	hypothetical LOC399959	11	-121465022	AW162210	399959	11q24.1	Hs.44098	2
228646_at	0.762	5.518	4.845	2.061e-04	0.034	0.876	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C	2	182558795	AI806944	151242	2q31.3	Hs.10941	3	phosphoprotein phosphatase inhibitor activity cytoplasm signal transduction
218265_at	-0.461	6.809	-4.837	2.091e-04	0.034	0.863	SECISBP2	SECIS binding protein 2	9	91123231	NM_024077	79048	9q22.2	Hs.59804	20	RNA binding mRNA 3'-UTR binding nucleus translation
219448_at	-2.166	7.532	-4.834	2.105e-04	0.034	0.857	TMEM70	transmembrane protein 70	8	75050983	BC002748	54968	8q21.11	Hs.106650	7	molecular_function mitochondrion membrane integral to membrane integral to mitochondrial membrane mitochondrial proton-transporting ATP synthase complex assembly
225326_at	-0.478	7.474	-4.833	2.107e-04	0.034	0.856	RBM27	RNA binding motif protein 27	5	145563355	AB037732	54439	5q32	Hs.61441	8	nucleotide binding RNA binding nucleus cytoplasm zinc ion binding nuclear speck metal ion binding
222287_at	-0.840	11.343	-4.833	2.109e-04	0.034	0.855	TRDN	triadin	6	-123579181	AW969675	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
222990_at	-0.421	9.423	-4.828	2.131e-04	0.034	0.846	UBQLN1	ubiquilin 1	9	-85464697	AW204104	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
226905_at	0.831	7.645	4.827	2.136e-04	0.034	0.843	FAM101B	family with sequence similarity 101, member B	17	-289998	BG036514	359845	17p13	Hs.345588 Hs.596411 Hs.719324	4
201288_at	0.767	7.825	4.813	2.194e-04	0.035	0.818	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	12	-14986216	NM_001175	397	12p12.3	Hs.504877	34	Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding cytoplasm cytoskeleton cell motion immune response negative regulation of cell adhesion Rho protein signal transduction multicellular organismal development cytoplasmic membrane-bounded vesicle actin cytoskeleton organization	Neurotrophin signaling pathway
200758_s_at	-0.580	11.205	-4.813	2.194e-04	0.035	0.818	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	AI361227	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
223044_at	0.605	9.868	4.802	2.241e-04	0.035	0.799	SLC40A1	solute carrier family 40 (iron-regulated transporter), member 1	2	-190133560	AL136944	30061	2q32	Hs.643005	73	iron ion transmembrane transporter activity iron ion binding cytoplasm plasma membrane integral to plasma membrane ion transport iron ion transport cellular iron ion homeostasis synaptic vesicle anatomical structure morphogenesis
220340_at	1.164	6.134	4.802	2.241e-04	0.035	0.799	KIAA1772	KIAA1772	18	17076200	NM_024935	80000	18q11.1-q11.2	Hs.149020	4	membrane integral to membrane
215884_s_at	-0.713	8.157	-4.802	2.244e-04	0.035	0.798	UBQLN2	ubiquilin 2	X	56606796	AK001029	29978	Xp11.23-p11.1	Hs.179309	20	binding nucleus cytoplasm plasma membrane
210867_at	-0.598	5.238	-4.795	2.274e-04	0.036	0.785	CNOT4	CCR4-NOT transcription complex, subunit 4	7	-134723303, -134697088	AF180475	4850	7q22-qter	Hs.490224	7	nucleotide binding RNA binding protein binding nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process regulation of transcription metal ion binding	RNA degradation
212248_at	-0.538	8.201	-4.793	2.281e-04	0.036	0.783	MTDH	metadherin	8	98725582	AI886796	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
231887_s_at	0.527	6.042	4.792	2.289e-04	0.036	0.779	KIAA1274	KIAA1274	10	71908569	AB033100	27143	10q22.1	Hs.202351	5
212935_at	0.547	6.813	4.784	2.323e-04	0.036	0.765	MCF2L	MCF.2 cell line derived transforming sequence-like	13	112670757, 112681655	AB002360	23263	13q34	Hs.170422 Hs.597691	15	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm mitochondrion plasma membrane intracellular signaling cascade regulation of Rho protein signal transduction
224918_x_at	1.822	6.884	4.782	2.331e-04	0.036	0.762	MGST1	microsomal glutathione S-transferase 1	12	16391342, 16391845, 16391978, 16397617	AI220117	4257	12p12.3-p12.1	Hs.389700	22	glutathione transferase activity mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum microsome glutathione metabolic process membrane transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
205603_s_at	-1.325	6.759	-4.782	2.333e-04	0.036	0.762	DIAPH2	diaphanous homolog 2 (Drosophila)	X	95826317, 95826317	NM_007309	1730	Xq21.33	Hs.226483 Hs.716101	14	cytokinesis actin binding receptor binding cytoplasm early endosome Golgi apparatus cytosol multicellular organismal development cellular component organization Rho GTPase binding actin cytoskeleton organization cell differentiation oogenesis	Regulation of actin cytoskeleton
205902_at	-0.762	6.119	-4.779	2.345e-04	0.036	0.757	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1	-152946536, -152946536	AJ251016	3782	1q21.3	Hs.490765	40	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
1554485_s_at	0.686	3.900	4.779	2.348e-04	0.036	0.756	TMEM37	transmembrane protein 37	2	119905915	BI825302	140738	2q14.2	Hs.26216	3	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane
215440_s_at	1.374	4.638	4.776	2.359e-04	0.036	0.751	BEX4	brain expressed, X-linked 4	X	102356675, 102356675	AL523320	56271	Xq22.1-q22.3	Hs.184736	4	nucleus cytoplasm
217992_s_at	0.429	5.492	4.775	2.364e-04	0.036	0.749	EFHD2	EF-hand domain family, member D2	1	15608977	NM_024329	79180	1p36.21	Hs.465374	8	calcium ion binding protein binding
201936_s_at	-1.113	7.459	-4.771	2.384e-04	0.036	0.741	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	1	-21005560	NM_003760	8672	1p36.12	Hs.467084	19	RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
201538_s_at	-0.705	7.274	-4.769	2.394e-04	0.036	0.737	DUSP3	dual specificity phosphatase 3	17	-39199014	NM_004090	1845	17q21	Hs.181046	21	protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleoplasm protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity	MAPK signaling pathway
241364_at	-0.874	7.624	-4.769	2.395e-04	0.036	0.737	TMEM57	transmembrane protein 57	1	25629974	AA827805	55219	1p36.11	Hs.189782	7	membrane integral to membrane
200914_x_at	-0.748	10.569	-4.769	2.396e-04	0.036	0.737	KTN1	kinectin 1 (kinesin receptor)	14	55116677, 55116677	BF589024	3895	14q22.1	Hs.509414	30	molecular_function membrane fraction endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane microtubule-based movement membrane
213012_at	-1.307	7.748	-4.764	2.415e-04	0.036	0.729	NEDD4	neural precursor cell expressed, developmentally down-regulated 4	15	-53906413, -53906413	D42055	4734	15q	Hs.1565	79	ubiquitin ligase complex chromatin ubiquitin-protein ligase activity intracellular membrane fraction cytoplasm cytosol plasma membrane cell cortex protein modification process protein targeting to lysosome pathogenesis negative regulation of sodium ion transport negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage positive regulation of phosphoinositide 3-kinase cascade apicolateral plasma membrane ligase activity acid-amino acid ligase activity transmission of virus sodium channel inhibitor activity protein domain specific binding modification-dependent protein catabolic process neuron projection development receptor internalization beta-2 adrenergic receptor binding receptor catabolic process cellular response to UV protein ubiquitination during ubiquitin-dependent protein catabolic process glucocorticoid receptor signaling pathway ubiquitin binding ubiquitin binding positive regulation of protein catabolic process positive regulation of nucleocytoplasmic transport perinuclear region of cytoplasm phosphoserine binding phosphothreonine binding progesterone receptor signaling pathway response to calcium ion RNA polymerase binding proline-rich region binding	Ubiquitin mediated proteolysis Endocytosis
207196_s_at	-0.501	8.706	-4.764	2.420e-04	0.036	0.728	TNIP1	TNFAIP3 interacting protein 1	5	-150389698	NM_006058	10318	5q32-q33.1	Hs.355141	31	protein binding intracellular nucleus cytoplasm translation defense response glycoprotein biosynthetic process pathogenesis negative regulation of viral genome replication
224839_s_at	1.120	7.443	4.763	2.423e-04	0.036	0.727	GPT2	glutamic pyruvate transaminase (alanine aminotransferase) 2	16	45475808, 45476602	BG328998	84706	16q12.1	Hs.460693	9	L-alanine:2-oxoglutarate aminotransferase activity transaminase activity biosynthetic process pyridoxal phosphate binding	Alanine, aspartate and glutamate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
201161_s_at	-0.613	12.823	-4.763	2.424e-04	0.036	0.726	CSDA	cold shock domain protein A	12	-10742944	NM_003651	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
223125_s_at	-0.608	9.410	-4.761	2.431e-04	0.036	0.723	C1orf21	chromosome 1 open reading frame 21	1	182622772	AL563236	81563	1q25	Hs.497159 Hs.719188	8
207087_x_at	0.607	11.167	4.755	2.459e-04	0.036	0.713	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_020478	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
213572_s_at	-0.708	6.314	-4.753	2.471e-04	0.036	0.708	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	6	-2778732	AI554300	1992	6p25	Hs.381167	18	serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity
228367_at	1.016	8.510	4.735	2.560e-04	0.037	0.675	ALPK2	alpha-kinase 2	18	-54299461	BE551416	115701	18q21.31-q21.32	Hs.628152	2	protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation kinase activity transferase activity
202492_at	-0.440	7.642	-4.734	2.565e-04	0.037	0.674	ATG9A	ATG9 autophagy related 9 homolog A (S. cerevisiae)	2	-219792345	NM_024085	79065	2q35	Hs.323363	10	autophagic vacuole formation autophagy protein transport membrane integral to membrane cytoplasmic vesicle
218309_at	0.483	7.017	4.727	2.604e-04	0.038	0.660	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	1	-20681470	NM_018584	55450	1p36.12	Hs.197922	4	plasma membrane calcium-dependent protein kinase inhibitor activity postsynaptic density synaptosome protein kinase binding cell junction dendrite cell soma synapse postsynaptic membrane
226876_at	0.728	7.080	4.725	2.612e-04	0.038	0.657	FAM101B	family with sequence similarity 101, member B	17	-289998	AI961778	359845	17p13	Hs.345588 Hs.596411 Hs.719324	4
229730_at	-1.007	9.352	-4.722	2.629e-04	0.038	0.651	SMTNL2	smoothelin-like 2	17	4434024, 4434582	AI193973	342527	17p13.2	Hs.441709	2
210694_s_at	0.664	5.799	4.721	2.631e-04	0.038	0.650	MID1	midline 1 (Opitz/BBB syndrome)	X	-10373595, -10373595, -10373595	AF041209	4281	Xp22	Hs.27695	38	microtubule cytoskeleton organization protein binding intracellular cytoplasm microtubule microtubule associated complex negative regulation of microtubule depolymerization pattern specification process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
228920_at	0.538	5.963	4.721	2.633e-04	0.038	0.649	ZNF260	zinc finger protein 260	19	-41693433	BE328273	339324	19q13.12	Hs.18103	5	DNA binding intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
218844_at	0.591	7.076	4.721	2.635e-04	0.038	0.649	ACSF2	acyl-CoA synthetase family member 2	17	45858517	NM_025149	80221	17q21.33	Hs.288959	7	nucleotide binding ATP binding mitochondrion lipid metabolic process fatty acid metabolic process metabolic process ligase activity
203138_at	-0.721	8.667	-4.715	2.664e-04	0.038	0.639	HAT1	histone acetyltransferase 1	2	172487180	NM_003642	8520	2q31.2-q33.1	Hs.632532	14	histone acetyltransferase activity protein binding nucleus cytoplasm DNA packaging chromatin silencing at telomere internal protein amino acid acetylation acyltransferase activity chromatin modification histone acetylation transferase activity
220076_at	-0.765	5.560	-4.712	2.679e-04	0.038	0.633	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	NM_019847	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
1556113_at	-0.439	5.615	-4.709	2.694e-04	0.038	0.628	DKFZp451A211	DKFZp451A211 protein	13		BC036906	400169	13q34	Hs.646609	1
228093_at	0.443	5.602	4.703	2.730e-04	0.038	0.616	ZNF599	zinc finger protein 599	19	-39940818	AW300140	148103	19q13.11	Hs.590961	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1553873_at	-1.421	7.926	-4.702	2.733e-04	0.038	0.615	KLHL34	kelch-like 34 (Drosophila)	X	-21583529	NM_153270	257240	Xp22.12	Hs.448572	4	protein binding
201662_s_at	-0.815	7.577	-4.701	2.739e-04	0.038	0.613	ACSL3	acyl-CoA synthetase long-chain family member 3	2	223433975	D89053	2181	2q34-q35	Hs.655772	20	nucleotide binding magnesium ion binding fatty-acyl-CoA synthase activity long-chain-fatty-acid-CoA ligase activity protein binding ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
202055_at	-0.724	8.509	-4.699	2.753e-04	0.038	0.608	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	AA652173	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
242660_at	0.894	3.258	4.698	2.759e-04	0.038	0.606	C10orf112	chromosome 10 open reading frame 112	10		AA846789	340895	10p12.31	Hs.662505	4	membrane integral to membrane
243439_at	0.646	5.722	4.697	2.760e-04	0.038	0.606	ZNF418	zinc finger protein 418	19	-63125063	AI971569	147686	19q13.43	Hs.660728	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208950_s_at	0.721	6.530	4.684	2.831e-04	0.039	0.582	ALDH7A1	aldehyde dehydrogenase 7 family, member A1	5	-125906816	BC002515	501	5q31	Hs.483239	19	aldehyde dehydrogenase (NAD) activity L-aminoadipate-semialdehyde dehydrogenase activity cellular_component mitochondrion cellular aldehyde metabolic process sensory perception of sound oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
206404_at	1.100	6.003	4.682	2.843e-04	0.039	0.578	FGF9	fibroblast growth factor 9 (glia-activating factor)	13	21143214	NM_002010	2254	13q11-q12	Hs.111	33	angiogenesis osteoblast differentiation positive regulation of mesenchymal cell proliferation chondrocyte differentiation extracellular region extracellular region extracellular space protein import into nucleus signal transduction cell-cell signaling growth factor activity heparin binding male gonad development negative regulation of Wnt receptor signaling pathway male sex determination lung development embryonic limb morphogenesis positive regulation of vascular endothelial growth factor receptor signaling pathway inner ear morphogenesis positive regulation of MAPKKK cascade positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of smoothened signaling pathway regulation of timing of cell differentiation embryonic gut development embryonic skeletal system development positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
212637_s_at	-0.992	8.355	-4.682	2.846e-04	0.039	0.577	WWP1	WW domain containing E3 ubiquitin protein ligase 1	8	87424109	AU155187	11059	8q21	Hs.655189	30	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding intracellular protein modification process signal transduction central nervous system development negative regulation of transcription protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process interspecies interaction between organisms entry of virus into host cell	Ubiquitin mediated proteolysis Endocytosis
217364_x_at	-0.728	5.559	-4.681	2.848e-04	0.039	0.577	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	AL031313	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
204067_at	0.464	7.561	4.680	2.859e-04	0.039	0.573	SUOX	sulfite oxidase	12	54677309	AA129776	6821	12q13.2	Hs.558403	23	mitochondrion mitochondrial intermembrane space cytosol response to nutrient sulfite oxidase activity electron carrier activity oxidoreductase activity heme binding molybdenum ion binding molybdopterin cofactor binding metal ion binding oxidation reduction	Sulfur metabolism
200978_at	0.484	12.281	4.677	2.873e-04	0.039	0.568	MDH1	malate dehydrogenase 1, NAD (soluble)	2	63669625	NM_005917	4190	2p13.3	Hs.526521	18	malic enzyme activity binding soluble fraction cytoplasm cytosol cytosol glycolysis tricarboxylic acid cycle oxaloacetate metabolic process malate metabolic process oxidoreductase activity NAD metabolic process L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
202823_at	-0.723	8.055	-4.671	2.911e-04	0.039	0.556	TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8	-75021187	N89607	6921	8q21.11	Hs.554594	46	protein binding nucleus nucleoplasm cytosol regulation of transcription from RNA polymerase II promoter ubiquitin-dependent protein catabolic process interspecies interaction between organisms regulation of transcription	Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma
227163_at	0.500	5.026	4.662	2.959e-04	0.040	0.541	GSTO2	glutathione S-transferase omega 2	10	106018620	AL162742	119391	10q25.1	Hs.203634	27	glutathione transferase activity cytoplasm metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
224505_s_at	-0.602	8.831	-4.651	3.024e-04	0.040	0.521	PLCD4	phospholipase C, delta 4	2	219180875	BC006355	84812	2q35	Hs.632528	19	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding nucleus cytoplasm endoplasmic reticulum intracellular signaling cascade membrane lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system
202919_at	-0.592	8.679	-4.650	3.031e-04	0.040	0.519	MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	2	198088564, 198089015	NM_015387	25843	2q33.1	Hs.645458	13	protein binding cytoplasm Golgi apparatus transport zinc ion binding membrane metal ion binding perinuclear region of cytoplasm
210246_s_at	0.644	5.357	4.648	3.044e-04	0.040	0.515	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	11	-17371007	AF087138	6833	11p15.1	Hs.54470	111	nucleotide binding receptor activity ATP binding plasma membrane carbohydrate metabolic process transport potassium ion transport sulfonylurea receptor activity potassium ion transmembrane transporter activity integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters Type II diabetes mellitus
224950_at	0.596	5.209	4.648	3.045e-04	0.040	0.514	PTGFRN	prostaglandin F2 receptor negative regulator	1	117254211	BF476250	5738	1p13.1	Hs.418093	14	protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane
201372_s_at	-1.412	5.309	-4.647	3.051e-04	0.040	0.513	CUL3	cullin 3	2	-225043112	NM_003590	8452	2q36.2	Hs.372286	39	G1/S transition of mitotic cell cycle protein binding nucleus Golgi apparatus ubiquitin-dependent protein catabolic process cell cycle arrest cyclin catabolic process positive regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
208690_s_at	1.077	10.641	4.645	3.061e-04	0.041	0.510	PDLIM1	PDZ and LIM domain 1	10	-96987319	BC000915	9124	10q22-q26.3	Hs.368525	19	transcription coactivator activity protein binding transcription factor complex cytoplasm cytoskeleton response to oxidative stress zinc ion binding regulation of transcription metal ion binding
228728_at	0.579	9.498	4.643	3.076e-04	0.041	0.505	C7orf58	chromosome 7 open reading frame 58	7	120415986, 120416680	BF724137	79974	7q31.31	Hs.189652	13	endoplasmic reticulum
213929_at	0.619	2.932	4.641	3.087e-04	0.041	0.502	EXPH5	exophilin 5	11	-107881367, -107881367, -107881367	AL050204	23086	11q22.3	Hs.28540	8	protein binding intracellular protein transport Rab GTPase binding
218193_s_at	-0.752	5.717	-4.637	3.113e-04	0.041	0.494	GOLT1B	golgi transport 1 homolog B (S. cerevisiae)	12	21545965	NM_016072	51026	12p12.1	Hs.62275	10	signal transducer activity endoplasmic reticulum Golgi apparatus protein transport membrane integral to membrane vesicle-mediated transport positive regulation of I-kappaB kinase/NF-kappaB cascade
205210_at	-0.371	5.527	-4.631	3.150e-04	0.041	0.483	TGFBRAP1	transforming growth factor, beta receptor associated protein 1	2	-105249973	NM_004257	9392	2q12.1	Hs.446350	7	transforming growth factor beta receptor binding cytoplasm signal transduction transforming growth factor beta receptor signaling pathway membrane regulation of transcription SMAD binding
218364_at	-0.712	8.099	-4.627	3.176e-04	0.041	0.475	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	NM_017724	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
234192_s_at	-0.724	8.574	-4.626	3.181e-04	0.041	0.474	GKAP1	G kinase anchoring protein 1	9	-85544156	AK026487	80318	9q21.32	Hs.522255	5	protein binding Golgi apparatus signal transduction
236813_at	0.594	5.600	4.625	3.186e-04	0.041	0.473	MORN4	MORN repeat containing 4	10	-99364299, -99364299	N21659	118812	10q24.2	Hs.217409	6
1569852_at	-1.387	7.982	-4.624	3.197e-04	0.041	0.469	C7orf53	chromosome 7 open reading frame 53	7	111908143, 111908301	BC031976	286006	7q31.1	Hs.396189	5	membrane integral to membrane
212250_at	-0.756	7.994	-4.621	3.211e-04	0.041	0.465	MTDH	metadherin	8	98725582	AV700332	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
222628_s_at	0.435	7.225	4.620	3.218e-04	0.041	0.463	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	AA195405	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
227474_at	1.092	5.040	4.615	3.251e-04	0.042	0.454	LOC654433	hypothetical LOC654433	2	113710316	AY007128	654433	2q13	Hs.656660	4
41577_at	0.615	5.424	4.615	3.254e-04	0.042	0.453	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AB020630	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
203235_at	0.359	6.272	4.614	3.258e-04	0.042	0.452	THOP1	thimet oligopeptidase 1	19	2736505	NM_003249	7064	19q13.3	Hs.78769	24	metalloendopeptidase activity protein binding cytoplasm proteolysis peptide metabolic process protein kinase cascade peptidase activity zinc ion binding metal ion binding	Renin-angiotensin system
220610_s_at	-0.714	6.899	-4.614	3.258e-04	0.042	0.452	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	NM_006309	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
203511_s_at	0.519	7.452	4.614	3.261e-04	0.042	0.451	TRAPPC3	trafficking protein particle complex 3	1	-36374759	AF041432	27095	1p34.3	Hs.523131	16	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol ER to Golgi vesicle-mediated transport vesicle-mediated transport TRAPP complex
200761_s_at	-0.605	10.622	-4.610	3.284e-04	0.042	0.444	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	3	69216779	NM_006407	10550	3p14	Hs.518060 Hs.716493	30	protein binding cytoplasm endoplasmic reticulum L-glutamate transport membrane integral to membrane
222103_at	-0.829	8.706	-4.610	3.284e-04	0.042	0.444	ATF1	activating transcription factor 1	12	49444085	AI434345	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
228831_s_at	0.594	6.001	4.607	3.307e-04	0.042	0.438	GNG7	guanine nucleotide binding protein (G protein), gamma 7	19	-2462217	AL039870	2788	19p13.3	Hs.515544	12	behavioral fear response signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction receptor guanylyl cyclase signaling pathway locomotory behavior regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
214889_at	1.571	5.527	4.604	3.323e-04	0.042	0.434	FAM149A	family with sequence similarity 149, member A	4	187302988, 187307320	AL080065	25854	4q35.1	Hs.357025	3
202056_at	-0.814	8.604	-4.604	3.323e-04	0.042	0.434	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	AW051311	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
221058_s_at	0.463	5.747	4.604	3.324e-04	0.042	0.433	CKLF	chemokine-like factor	16	65143966, 65143972	NM_016326	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
1556121_at	-0.954	6.152	-4.602	3.336e-04	0.042	0.430	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AK021751	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
225547_at	-0.786	10.993	-4.602	3.336e-04	0.042	0.430	SNHG6	small nucleolar RNA host gene 6 (non-protein coding)	8	-67996718	BG169443	641638	8q13	Hs.372680	1
205334_at	0.756	8.764	4.601	3.344e-04	0.042	0.428	S100A1	S100 calcium binding protein A1	1	151867496	NM_006271	6271	1q21	Hs.515715	55	calcium ion binding cytoplasm intracellular signaling cascade regulation of heart contraction zinc ion binding sarcoplasmic reticulum protein homodimerization activity protein complex S100 beta binding S100 alpha binding ATPase binding
208913_at	-0.663	7.188	-4.599	3.359e-04	0.042	0.423	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	16	-23383143	AA868560	23062	16p12	Hs.460336	37	protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding	Lysosome
201160_s_at	-0.350	12.837	-4.597	3.372e-04	0.042	0.420	CSDA	cold shock domain protein A	12	-10742944	AL556190	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
211698_at	-0.527	8.884	-4.595	3.383e-04	0.042	0.417	EID1	EP300 interacting inhibitor of differentiation 1	15	46957581	AF349444	23741	15q21.1-q21.2	Hs.255973 Hs.714048	12	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding cellular_component nucleus cytoplasm cell cycle specific transcriptional repressor activity cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of transcription
236514_at	0.952	5.262	4.594	3.389e-04	0.042	0.415	ACOT8	acyl-CoA thioesterase 8	20	-43903767	AI885067	10005	20q13.12	Hs.444776	18	carboxylesterase activity protein binding peroxisome lipid metabolic process acyl-CoA metabolic process peroxisome organization acyl-CoA thioesterase activity hydrolase activity choloyl-CoA hydrolase activity interspecies interaction between organisms
202289_s_at	-0.591	10.658	-4.592	3.408e-04	0.042	0.410	TACC2	transforming, acidic coiled-coil containing protein 2	10	123738678, 123913094	NM_006997	10579	10q26	Hs.501252 Hs.713875	18	protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding
227718_at	-0.912	6.497	-4.591	3.412e-04	0.042	0.409	PURB	purine-rich element binding protein B	7	-44882416	BF337790	5814	7p13	Hs.349150 Hs.596321	13	translation repressor activity, nucleic acid binding double-stranded DNA binding single-stranded DNA binding transcription factor activity mRNA binding nucleus DNA replication factor A complex transcription factor binding specific transcriptional repressor activity purine-rich negative regulatory element binding regulation of transcription regulation of myeloid cell differentiation negative regulation of transcription, DNA-dependent SMAD binding
236294_at	-0.411	5.729	-4.591	3.415e-04	0.042	0.408	HUWE1	HECT, UBA and WWE domain containing 1	X	-53575796	R37670	10075	Xp11.22	Hs.136905	28	protein polyubiquitination DNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm protein modification process histone ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation	Ubiquitin mediated proteolysis
212293_at	-0.760	7.620	-4.587	3.440e-04	0.042	0.401	HIPK1	homeodomain interacting protein kinase 1	1	114273518, 114273518, 114295289, 114298021	BG111260	204851	1p13.2	Hs.532363	11	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleolus cytoplasm centrosome protein amino acid phosphorylation transferase activity regulation of transcription
223000_s_at	0.611	6.332	4.585	3.454e-04	0.042	0.398	F11R	F11 receptor	1	-159231624	AF172398	50848	1q21.2-q21.3	Hs.517293	63	protein binding plasma membrane cell-cell junction tight junction inflammatory response cell adhesion integral to membrane epithelial cell differentiation interspecies interaction between organisms	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
217724_at	-0.437	11.090	-4.581	3.483e-04	0.042	0.390	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	AF131807	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
225811_at	-0.620	9.799	-4.576	3.512e-04	0.042	0.382	C11orf58	chromosome 11 open reading frame 58	11	16716723	AI652868	10944	11p15.1	Hs.719128	8	molecular_function cellular_component biological_process
228452_at	-0.765	6.951	-4.573	3.536e-04	0.042	0.376	C17orf39	chromosome 17 open reading frame 39	17	17883335	AA827865	79018	17p11.2	Hs.187422	5
208407_s_at	0.572	6.604	4.571	3.554e-04	0.043	0.371	CTNND1	catenin (cadherin-associated protein), delta 1	11	57285809	NM_001331	1500	11q11	Hs.166011	99	protein binding nucleus cytoplasm plasma membrane Wnt receptor signaling pathway cell-cell adhesion cadherin binding regulation of transcription	Adherens junction Leukocyte transendothelial migration
214077_x_at	0.628	4.459	4.564	3.599e-04	0.043	0.360	MEIS3P1	Meis homeobox 3 pseudogene 1	17	15630888	H15129	4213	17p12	Hs.356135	4	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
219035_s_at	-0.689	8.558	-4.564	3.601e-04	0.043	0.359	RNF34	ring finger protein 34	12	120322284	NM_025126	80196	12q24.31	Hs.292804	11	protein binding nucleus apoptosis zinc ion binding membrane nuclear speck ligase activity modification-dependent protein catabolic process metal ion binding
206303_s_at	-0.607	6.900	-4.563	3.609e-04	0.043	0.357	NUDT4	nudix (nucleoside diphosphate linked moiety X)-type motif 4	12	92295831	AF191653	11163	12q21	Hs.506325	10	magnesium ion binding intracellular cytoplasm intracellular signaling cascade diphosphoinositol-polyphosphate diphosphatase activity cyclic nucleotide metabolic process hydrolase activity calcium-mediated signaling cyclic-nucleotide-mediated signaling manganese ion binding regulation of RNA export from nucleus intracellular transport
203403_s_at	-0.855	8.283	-4.562	3.613e-04	0.043	0.356	RNF6	ring finger protein (C3H2C3 type) 6	13	-25684904, -25684904, -25684904	NM_005977	6049	13q12.2	Hs.136885	7	protein binding cellular_component biological_process zinc ion binding metal ion binding
231736_x_at	1.646	6.514	4.561	3.619e-04	0.043	0.354	MGST1	microsomal glutathione S-transferase 1	12	16391342, 16391845, 16391978, 16397617	NM_020300	4257	12p12.3-p12.1	Hs.389700	22	glutathione transferase activity mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum microsome glutathione metabolic process membrane transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
1554679_a_at	-2.023	8.658	-4.556	3.663e-04	0.043	0.343	LAPTM4B	lysosomal protein transmembrane 4 beta	8	98856984	AF317417	55353	8q22.1	Hs.492314	17	transport endomembrane system membrane integral to membrane	Lysosome
221232_s_at	-2.512	9.431	-4.554	3.675e-04	0.043	0.340	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	10	99322245	NM_020349	26287	10q23.31-q23.32	Hs.73708	17	muscle organ development structural constituent of muscle I band
200992_at	-0.389	9.968	-4.551	3.695e-04	0.043	0.335	IPO7	importin 7	11	9362744	AL137335	10527	11p15.4	Hs.718440	22	protein import into nucleus, docking small GTPase regulator activity transporter activity soluble fraction nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity histone binding interspecies interaction between organisms
210257_x_at	-0.553	4.790	-4.549	3.711e-04	0.043	0.331	CUL4B	cullin 4B	X	-119542473, -119542473	AF212995	8450	Xq23	Hs.102914	28	molecular_function protein binding cellular_component DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
205391_x_at	0.601	11.171	4.546	3.733e-04	0.044	0.326	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	M28880	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
220416_at	0.489	2.895	4.545	3.744e-04	0.044	0.323	ATP8B4	ATPase, class I, type 8B, member 4	15	-47937726	NM_024837	79895	15q21.2	Hs.511311	7	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
222402_at	-0.623	7.467	-4.543	3.757e-04	0.044	0.319	POMP	proteasome maturation protein	13	28131240	BC003390	51371	13q12.3	Hs.268742	13	nucleus cytoplasm cytosol immune response protein complex	Proteasome
227031_at	-0.647	7.445	-4.536	3.806e-04	0.044	0.307	SNX13	sorting nexin 13	7	-17796910	AV681975	23161	7p21.1	Hs.487648	10	signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding
221838_at	0.397	4.960	4.536	3.813e-04	0.044	0.306	KLHL22	kelch-like 22 (Drosophila)	22	-19125805	N38751	84861	22q11.21	Hs.517419	6	protein binding
201724_s_at	-0.460	6.968	-4.535	3.815e-04	0.044	0.305	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	NM_020474	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
202985_s_at	-0.453	6.914	-4.532	3.843e-04	0.044	0.298	BAG5	BCL2-associated athanogene 5	14	-103092641, -103092641, -103092641	NM_004873	9529	14q32.33	Hs.5443	10	protein binding protein folding apoptosis
212428_at	-0.730	9.043	-4.531	3.851e-04	0.044	0.296	KIAA0368	KIAA0368	9	-113162793	AW001101	23392	9q31.3	Hs.368255	12	proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process
219330_at	0.432	4.051	4.530	3.859e-04	0.044	0.295	VANGL1	vang-like 1 (van gogh, Drosophila)	1	115986096	NM_024062	81839	1p11-p13.1	Hs.515130	12	protein binding multicellular organismal development membrane integral to membrane	Wnt signaling pathway
218534_s_at	-0.674	6.554	-4.527	3.878e-04	0.044	0.290	AGGF1	angiogenic factor with G patch and FHA domains 1	5	76361987	NM_018046	55109	5q13.3	Hs.634849	12	vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm
226395_at	-0.861	7.792	-4.524	3.904e-04	0.044	0.284	HOOK3	hook homolog 3 (Drosophila)	8	42871189	AI912618	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
205771_s_at	-1.158	7.942	-4.520	3.937e-04	0.045	0.276	AKAP7	A kinase (PRKA) anchor protein 7	6	131508153, 131613196	AL137063	9465	6q23	Hs.486483	9	catalytic activity intracellular cytoplasm cytosol plasma membrane ion transport intracellular signaling cascade protein localization biological_process RNA metabolic process apical plasma membrane lateral plasma membrane protein kinase A binding protein kinase A binding
239093_at	0.674	4.587	4.519	3.944e-04	0.045	0.274	DHDPSL	dihydrodipicolinate synthase-like, mitochondrial	10	99334091	BG165743	112817	10q24.2	Hs.180346	4	mitochondrion metabolic process lyase activity
235122_at	0.704	4.554	4.508	4.029e-04	0.045	0.255	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	1	-41748270	AI800713	59269	1p34	Hs.648369 Hs.715958	12	DNA binding intracellular nucleus cytoplasm zinc ion binding transcription activator activity positive regulation of transcription metal ion binding
1553286_at	0.685	4.888	4.503	4.066e-04	0.046	0.246	ZNF555	zinc finger protein 555	19	2792481	NM_152791	148254	19p13.3	Hs.47712	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
49329_at	0.334	6.655	4.503	4.073e-04	0.046	0.245	KLHL22	kelch-like 22 (Drosophila)	22	-19125805	N38751	84861	22q11.21	Hs.517419	6	protein binding
230055_at	0.489	5.283	4.502	4.074e-04	0.046	0.244	KHDC1	KH homology domain containing 1	6	-74007758	AL037414	80759	6q13	Hs.715645	4	RNA binding membrane integral to membrane
223693_s_at	0.410	5.902	4.501	4.088e-04	0.046	0.241	RADIL	Ras association and DIL domains	7	-4805265	AL136731	55698	7p22.1	Hs.667336	13	protein binding cell adhesion signal transduction multicellular organismal development
224666_at	0.441	7.798	4.500	4.094e-04	0.046	0.240	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	16	-27143815	AF161451	197370	16p12.1	Hs.284295	6	nucleus DNA repair DNA recombination response to DNA damage stimulus zinc ion binding metal ion binding
228501_at	0.819	5.727	4.499	4.104e-04	0.046	0.237	GALNTL2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	3	16191187	BF055343	117248	3p25.1	Hs.411308	10	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups transport vesicle manganese ion binding	O-Glycan biosynthesis Metabolic pathways
212915_at	-1.048	9.177	-4.497	4.116e-04	0.046	0.235	PDZRN3	PDZ domain containing ring finger 3	3	-73514341	AL569804	23024	3p13	Hs.719126	9	protein binding zinc ion binding metal ion binding
226247_at	-0.616	7.755	-4.492	4.163e-04	0.046	0.224	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	10	124124209, 124141832	AI346026	59338	10q26.13	Hs.643512	16	phospholipid binding cellular_component nucleus cytoplasm plasma membrane biological_process
202946_s_at	-0.731	7.012	-4.491	4.172e-04	0.046	0.222	BTBD3	BTB (POZ) domain containing 3	20	11819476, 11846564	NM_014962	22903	20p12.2	Hs.709366	5	protein binding
228483_s_at	-0.807	4.947	-4.491	4.172e-04	0.046	0.222	TAF9B	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	X	-77271900, 1383006	BE856250	51616	Xq13.1-q21.1	Hs.592248 Hs.643614 Hs.714006	8	DNA binding transcription corepressor activity protein binding nucleus transcription factor TFIID complex transcription initiation negative regulation of specific transcription from RNA polymerase II promoter positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptosis regulation of transcription	Basal transcription factors
212168_at	-0.500	5.686	-4.487	4.206e-04	0.046	0.215	RBM12	RNA binding motif protein 12	20	-33700292	AL514547	10137	20q11.21	Hs.246413	13	nucleotide binding RNA binding protein binding nucleus
225007_at	-0.527	7.564	-4.484	4.229e-04	0.046	0.210	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	AV705516	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
243617_at	0.481	6.123	4.484	4.232e-04	0.046	0.209	ZNF827	zinc finger protein 827	4	-146901337	BF678830	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
208667_s_at	-0.686	10.144	-4.483	4.236e-04	0.046	0.208	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22	-39550546	U17714	6767	22q13.2	Hs.712713	29	binding cytoplasm protein folding protein binding, bridging
228790_at	-0.835	6.461	-4.481	4.253e-04	0.046	0.204	FAM110B	family with sequence similarity 110, member B	8	59069666	AW264082	90362	8q12.1	Hs.154652	7	cytoplasm mitochondrion centrosome
209242_at	0.935	4.967	4.481	4.257e-04	0.046	0.203	PEG3	paternally expressed 3	19	-62013256, -62013256	AL042588	5178	19q13.4	Hs.719209	18	nucleic acid binding transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent apoptosis zinc ion binding metal ion binding
218150_at	-0.521	9.360	-4.477	4.285e-04	0.046	0.197	ARL5A	ADP-ribosylation factor-like 5A	2	-152365725	NM_012097	26225	2q23.3	Hs.470233	6	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
213754_s_at	-0.651	9.031	-4.476	4.297e-04	0.046	0.195	PAIP1	poly(A) binding protein interacting protein 1	5	-43562126, -43562126	AW613203	10605	5p12	Hs.482038	12	RNA binding protein binding cytoplasm translational initiation regulation of translation translation activator activity RNA metabolic process mRNA stabilization
210691_s_at	-0.502	8.089	-4.475	4.304e-04	0.046	0.193	CACYBP	calcyclin binding protein	1	173235193, 173235514	AF275803	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
236635_at	0.913	4.890	4.475	4.310e-04	0.046	0.192	ZNF667	zinc finger protein 667	19	-61643017	AI332774	63934	19q13.43	Hs.712574	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
238844_s_at	-0.842	5.808	-4.472	4.328e-04	0.046	0.188	NPHP1	nephronophthisis 1 (juvenile)	2	-110238202	BF216535	4867	2q13	Hs.280388	36	structural molecule activity protein binding adherens junction signal transduction excretion visual behavior membrane cell-cell adhesion actin cytoskeleton organization cell junction
202057_at	-0.692	7.254	-4.471	4.343e-04	0.046	0.185	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	BC002374	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
228372_at	0.502	6.539	4.470	4.350e-04	0.046	0.183	C10orf128	chromosome 10 open reading frame 128	10	-50033896	AW204712	170371	10q11.23	Hs.385493	1	membrane integral to membrane
231560_at	-0.483	2.546	-4.470	4.351e-04	0.046	0.183	LRRC34	leucine rich repeat containing 34	3	-170993957	D59759	151827	3q26.2	Hs.591289	3
1556601_a_at	0.391	4.468	4.468	4.366e-04	0.046	0.180	SPATA13	spermatogenesis associated 13	13	23632886	R69077	221178	13q12.12	Hs.657121	7	Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
1554678_s_at	-0.475	8.367	-4.467	4.372e-04	0.046	0.179	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	AB066484	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
228749_at	-0.579	6.300	-4.467	4.380e-04	0.046	0.177	ZDBF2	zinc finger, DBF-type containing 2	2	206847767	AV734793	57683	2q33.3	Hs.110489	3	nucleic acid binding zinc ion binding metal ion binding
201361_at	-0.416	7.562	-4.463	4.410e-04	0.046	0.171	TMEM109	transmembrane protein 109	11	60437946	NM_024092	79073	11q12.2	Hs.13662	5	molecular_function cellular_component nucleus nucleolus cytoplasm biological_process membrane integral to membrane sarcoplasmic reticulum nuclear membrane
241827_at	0.609	6.408	4.463	4.412e-04	0.046	0.170	ZNF615	zinc finger protein 615	19	-57186399	AL577866	284370	19q13.41	Hs.368355	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
244552_at	0.335	3.580	4.461	4.425e-04	0.046	0.167	ZNF788	zinc finger family member 788	19	12064077	AI190287	388507	19p13.2	Hs.127473		DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
209619_at	0.854	7.841	4.455	4.484e-04	0.047	0.155	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	5	-149761394, -149761392	K01144	972	5q32	Hs.436568	58	prostaglandin biosynthetic process intracellular protein complex assembly intracellular protein transport immune response signal transduction cell proliferation membrane integral to membrane immunoglobulin mediated immune response antigen processing and presentation of endogenous antigen cytokine binding MHC class II protein binding identical protein binding regulation of macrophage activation negative regulation of apoptosis T cell selection	Antigen processing and presentation
222471_s_at	-0.672	9.130	-4.454	4.494e-04	0.047	0.153	KCMF1	potassium channel modulatory factor 1	2	85051741	AI743396	56888	2p11.2	Hs.654968	7	intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
222235_s_at	-0.676	6.103	-4.454	4.496e-04	0.047	0.153	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	10	42953939	AL139812	55454	10q11.21	Hs.657569	6	protein binding Golgi apparatus membrane integral to membrane transferase activity integral to Golgi membrane Golgi cisterna membrane metal ion binding glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Chondroitin sulfate biosynthesis Metabolic pathways
214030_at	-0.425	7.447	-4.452	4.511e-04	0.047	0.150	CRYBG3	beta-gamma crystallin domain containing 3	3	99078508	BE501352	131544	3q11.2	Hs.714457	2	sugar binding
228555_at	-0.556	6.532	-4.448	4.544e-04	0.047	0.143	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	4	-114597792, -114591638	AA029441	817	4q26	Hs.144114	29	G1/S transition of mitotic cell cycle nucleotide binding regulation of cell growth calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm calcium- and calmodulin-dependent protein kinase complex calcium ion transport transferase activity T-tubule protein amino acid autophosphorylation cardiac muscle contraction	ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma
212567_s_at	-0.494	8.340	-4.445	4.571e-04	0.047	0.137	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AL523310	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
208951_at	0.785	6.233	4.445	4.574e-04	0.047	0.137	ALDH7A1	aldehyde dehydrogenase 7 family, member A1	5	-125906816	BC002515	501	5q31	Hs.483239	19	aldehyde dehydrogenase (NAD) activity L-aminoadipate-semialdehyde dehydrogenase activity cellular_component mitochondrion cellular aldehyde metabolic process sensory perception of sound oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
226573_at	1.067	5.920	4.444	4.579e-04	0.047	0.136	DIRAS1	DIRAS family, GTP-binding RAS-like 1	19	-2665564	AI829795	148252	19p13.3	Hs.172753	6	nucleotide binding GTP binding intracellular plasma membrane small GTPase mediated signal transduction
231940_at	0.665	6.712	4.444	4.584e-04	0.047	0.135	ZNF529	zinc finger protein 529	19	-41762996, -41726357, -41726357	AI369933	57711	19q13.13	Hs.708146	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
215716_s_at	-0.628	7.194	-4.443	4.595e-04	0.047	0.133	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	12	-88505956	L14561	490	12q21.3	Hs.506276	38	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
229139_at	-1.029	10.879	-4.441	4.613e-04	0.047	0.129	JPH1	junctophilin 1	8	-75309492	AI202201	56704	8q21	Hs.657367	9	molecular_function microsome plasma membrane muscle organ development structural constituent of muscle junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc junctional membrane complex regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
207537_at	-1.197	7.178	-4.440	4.616e-04	0.047	0.128	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	X	-54976314	NM_002625	5207	Xp11.21	Hs.444304	11	nucleotide binding 6-phosphofructo-2-kinase activity 6-phosphofructo-2-kinase activity fructose-2,6-bisphosphate 2-phosphatase activity fructose-2,6-bisphosphate 2-phosphatase activity ATP binding cytosol fructose 2,6-bisphosphate metabolic process gluconeogenesis glycolysis protein kinase cascade metabolic process kinase activity transferase activity hydrolase activity identical protein binding 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex	Fructose and mannose metabolism
203557_s_at	0.592	7.550	4.437	4.644e-04	0.047	0.123	PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	10	-72313272	NM_000281	5092	10q22	Hs.3192	28	transcription coactivator activity phenylalanine 4-monooxygenase activity nucleus cytoplasm tetrahydrobiopterin biosynthetic process 4-alpha-hydroxytetrahydrobiopterin dehydratase activity lyase activity identical protein binding regulation of protein homodimerization activity positive regulation of transcription protein homotetramerization protein heterooligomerization
228908_s_at	0.385	5.000	4.437	4.652e-04	0.047	0.121	LOC642852	hypothetical LOC642852	21	45532394	AW131553	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
238315_s_at	0.597	3.990	4.431	4.702e-04	0.048	0.111	ZNF567	zinc finger protein 567	19	41872141	BF061829	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213541_s_at	0.495	5.211	4.431	4.707e-04	0.048	0.110	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	21	-38673821, -38673821	AI351043	2078	21q22.3	Hs.473819	66	transcription factor activity signal transducer activity protein binding nucleus regulation of transcription, DNA-dependent protein amino acid phosphorylation signal transduction multicellular organismal development cell proliferation sequence-specific DNA binding
235554_x_at	-0.714	4.814	-4.427	4.738e-04	0.048	0.104	PACRGL	PARK2 co-regulated-like	4	20311133	BE048198	133015	4p15.31	Hs.479298	5	binding
1555630_a_at	0.493	6.032	4.426	4.753e-04	0.048	0.101	RAB34	RAB34, member RAS oncogene family	17	-24065425, -24065425, -24065425	AF327350	83871	17q11.2	Hs.301853	16	nucleotide binding ruffle GTPase activity GTP binding cytoplasm early endosome Golgi apparatus endocytosis small GTPase mediated signal transduction protein transport guanyl nucleotide binding
202376_at	1.195	5.401	4.419	4.816e-04	0.048	0.089	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	14	94148466	NM_001085	12	14q32.1	Hs.534293 Hs.710488	134	DNA binding serine-type endopeptidase inhibitor activity protein binding extracellular region intracellular nucleus acute-phase response inflammatory response regulation of lipid metabolic process peptidase inhibitor activity
228342_s_at	-1.131	8.465	-4.419	4.820e-04	0.048	0.088	ALPK3	alpha-kinase 3	15	83160914	AA843297	57538	15q25.2	Hs.459183	5	protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation multicellular organismal development heart development kinase activity transferase activity
35147_at	0.582	6.873	4.418	4.826e-04	0.048	0.087	MCF2L	MCF.2 cell line derived transforming sequence-like	13	112670757, 112681655	AB002360	23263	13q34	Hs.170422 Hs.597691	15	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm mitochondrion plasma membrane intracellular signaling cascade regulation of Rho protein signal transduction
214959_s_at	-0.643	4.404	-4.417	4.840e-04	0.048	0.084	API5	apoptosis inhibitor 5	11	43290080	AF229253	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
206204_at	1.568	5.316	4.416	4.846e-04	0.048	0.083	GRB14	growth factor receptor-bound protein 14	2	-165057568	NM_004490	2888	2q22-q24	Hs.411881	19	SH3/SH2 adaptor activity protein binding cytoplasm endosome microsome Golgi apparatus plasma membrane signal transduction
231056_at	0.441	5.900	4.410	4.910e-04	0.049	0.071	LOC339352	similar to Putative ATP-binding domain-containing protein 3-like protein	19		AI479923	339352	19q13.41
1555363_s_at	0.351	5.734	4.409	4.917e-04	0.049	0.070	LOC284440	hypothetical LOC284440	19	-19728182	BC034236	284440	19p13.11	Hs.665307	4
218310_at	-0.543	7.602	-4.409	4.922e-04	0.049	0.069	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	7	65843077	NM_014504	27342	7q11.21	Hs.530053	20	DNA binding protein binding cytoplasm early endosome endocytosis zinc ion binding protein transport modification-dependent protein catabolic process metal ion binding recycling endosome
1552734_at	-0.354	3.951	-4.400	5.004e-04	0.049	0.053	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	NM_152756	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
201601_x_at	0.827	9.171	4.398	5.024e-04	0.049	0.050	IFITM1	interferon induced transmembrane protein 1 (9-27)	11	303990	NM_003641	8519	11p15.5	Hs.458414	16	receptor signaling protein activity protein binding plasma membrane cell surface receptor linked signal transduction negative regulation of cell proliferation response to biotic stimulus integral to membrane	B cell receptor signaling pathway
228561_at	-0.970	6.687	-4.396	5.051e-04	0.049	0.045	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1	9	4669565	BF510563	55664	9p24.1	Hs.561954	6	protein binding cytoplasm
222478_at	-0.502	7.940	-4.395	5.057e-04	0.049	0.043	VPS36	vacuolar protein sorting 36 homolog (S. cerevisiae)	13	-51884737	AL576924	51028	13q14.3	Hs.109520	11	nucleus cytoplasm lysosome late endosome lipid binding protein transport ubiquitin binding regulation of transcription	Endocytosis
221645_s_at	0.822	4.360	4.395	5.059e-04	0.049	0.043	ZNF83	zinc finger protein 83	19	-57807429, -57807429	M27877	55769	19q13.3	Hs.467210 Hs.655934 Hs.659798 Hs.710125	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207757_at	0.568	4.480	4.394	5.066e-04	0.049	0.042	ZFP2	zinc finger protein 2 homolog (mouse)	5	178255521	NM_030613	80108	5q35.3	Hs.654533	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
200911_s_at	0.429	8.684	4.394	5.069e-04	0.049	0.041	TACC1	transforming, acidic coiled-coil containing protein 1	8	38704860, 38763878	NM_006283	6867	8p11.22	Hs.279245	22	protein binding nucleus cytoplasm cell cycle cell division
238547_at	-0.760	6.457	-4.393	5.081e-04	0.049	0.039	HEXIM2	hexamthylene bis-acetamide inducible 2	17	40594046	AI972367	124790	17q21.31	Hs.56382	9	negative regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm transcription repressor activity snRNA binding regulation of transcription negative regulation of cyclin-dependent protein kinase activity
225894_at	-0.619	11.477	-4.393	5.084e-04	0.049	0.038	SYNPO2	synaptopodin 2	4	120029443, 120029443	AL589603	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
231045_x_at	-0.403	8.514	-4.392	5.090e-04	0.049	0.037	C11orf31	chromosome 11 open reading frame 31	11	57265297	H29876	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
236565_s_at	1.730	6.053	4.392	5.092e-04	0.049	0.037	LARP6	La ribonucleoprotein domain family, member 6	15	-68930821, -68910942	BF792126	55323	15q23	Hs.416755	5	RNA binding nucleus cytoplasm RNA processing ribonucleoprotein complex
225701_at	0.483	5.259	4.388	5.127e-04	0.049	0.031	AKNA	AT-hook transcription factor	9	-116136254	AK024431	80709	9q32	Hs.494895	5	DNA binding nucleus regulation of transcription
225790_at	-0.867	7.260	-4.386	5.151e-04	0.049	0.026	MSRB3	methionine sulfoxide reductase B3	12	63958754	AL048386	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
212678_at	-0.416	5.639	-4.385	5.160e-04	0.049	0.025	NF1	neurofibromin 1	17	26446120, 26446120	AW054826	4763	17q11.2	Hs.113577	204	osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction	MAPK signaling pathway
204821_at	0.624	4.520	4.385	5.165e-04	0.049	0.024	BTN3A3	butyrophilin, subfamily 3, member A3	6	26548741	NM_006994	10384	6p21.3	Hs.167741	9	membrane integral to membrane
228608_at	0.694	3.211	4.384	5.173e-04	0.049	0.022	NALCN	sodium leak channel, non-selective	13	-100504130	N49852	259232	13q32.3	Hs.525146	8	voltage-gated ion channel activity sodium channel activity ion transport sodium ion transport membrane integral to membrane sodium ion binding
202128_at	-0.578	6.577	-4.379	5.227e-04	0.049	0.013	KIAA0317	KIAA0317	14	-74197707	NM_014821	9870	14q24.3	Hs.497417	4	intracellular protein modification process membrane integral to membrane acid-amino acid ligase activity modification-dependent protein catabolic process
235910_x_at	0.487	4.300	4.378	5.238e-04	0.049	0.011	ZNF316	zinc finger protein 316	7		BE674951	100131017	7p22.1	Hs.112668	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
233825_s_at	-0.823	7.468	-4.377	5.242e-04	0.049	0.010	CD99L2	CD99 molecule-like 2	X	-149685466	AU158444	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
225568_at	0.357	7.284	4.375	5.262e-04	0.049	0.006	TMEM141	transmembrane protein 141	9	138805597	BE728983	85014	9q34.3	Hs.356744	4	membrane integral to membrane
1559965_at	-0.622	5.394	-4.375	5.263e-04	0.049	0.006	LOC100192378	hypothetical LOC100192378	8	-77685669	BC037827	100192378	8q21.11	Hs.648649	2
200973_s_at	-0.871	9.408	-4.375	5.268e-04	0.049	0.005	TSPAN3	tetraspanin 3	15	-75125385	NM_005724	10099	15q24.3	Hs.5062 Hs.716484	8	membrane integral to membrane
202824_s_at	-0.375	10.120	-4.375	5.269e-04	0.049	0.005	TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	8	-75021187	NM_005648	6921	8q21.11	Hs.554594	46	protein binding nucleus nucleoplasm cytosol regulation of transcription from RNA polymerase II promoter ubiquitin-dependent protein catabolic process interspecies interaction between organisms regulation of transcription	Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma
213236_at	0.541	6.980	4.375	5.270e-04	0.049	0.005	SASH1	SAM and SH3 domain containing 1	6	148705421	AK025495	23328	6q24.3	Hs.193133	12	protein binding
209683_at	-0.631	5.220	-4.375	5.271e-04	0.049	0.005	FAM49A	family with sequence similarity 49, member A	2	-16597381	AA243659	81553	2p24.2	Hs.467769	8	intracellular
201980_s_at	0.699	6.760	4.374	5.278e-04	0.049	0.004	RSU1	Ras suppressor protein 1	10	-16672622	NM_012425	6251	10p13	Hs.524161	17	protein binding signal transduction
204773_at	0.329	7.128	4.373	5.293e-04	0.049	0.001	IL11RA	interleukin 11 receptor, alpha	9	34642181, 34643931, 34643931	NM_004512	3590	9p13	Hs.591088	26	cytokine receptor activity integral to plasma membrane membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
224791_at	0.637	6.646	4.371	5.313e-04	0.050	-0.003	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	8	-131133534	AW513835	50807	8q24.1-q24.2	Hs.655552	19	protein binding cytoplasm ARF GTPase activator activity zinc ion binding membrane regulation of ARF GTPase activity metal ion binding	Endocytosis Fc gamma R-mediated phagocytosis
222543_at	-0.704	7.526	-4.364	5.389e-04	0.050	-0.016	DERL1	Der1-like domain family, member 1	8	-124094748	AF131854	79139	8q24.13	Hs.241576	28	receptor activity protein binding endoplasmic reticulum endoplasmic reticulum response to unfolded protein protein transport membrane integral to membrane intracellular transport of viral proteins in host cell integral to endoplasmic reticulum membrane ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol MHC class I protein binding interspecies interaction between organisms	Amyotrophic lateral sclerosis (ALS)
228953_at	-0.698	6.967	-4.363	5.395e-04	0.050	-0.017	WHAMM	WAS protein homolog associated with actin, golgi membranes and microtubules	15	81275026	AI023634	123720	15q25.2	Hs.377360	5	actin binding cytoplasm ER-Golgi intermediate compartment Golgi apparatus membrane cytoplasmic vesicle membrane cytoplasmic vesicle
215119_at	1.556	5.238	4.363	5.401e-04	0.050	-0.018	MYO16	myosin XVI	13	108046500	AI522028	23026	13q33.3	Hs.656587	7	nucleotide binding motor activity ATP binding nucleoplasm cytoplasm plasma membrane negative regulation of cell proliferation myosin complex cerebellum development negative regulation of S phase of mitotic cell cycle perinuclear region of cytoplasm actin filament binding
207996_s_at	-1.095	6.652	-4.360	5.431e-04	0.050	-0.023	C18orf1	chromosome 18 open reading frame 1	18	13208785, 13601664, 13610866	NM_004338	753	18p11.2	Hs.149363	9	molecular_function plasma membrane biological_process integral to membrane
227100_at	-0.669	5.464	-4.360	5.435e-04	0.050	-0.024	B3GALTL	beta 1,3-galactosyltransferase-like	13	30672111	AI569766	145173	13q12.3	Hs.13205	11	endoplasmic reticulum carbohydrate metabolic process fucose metabolic process membrane integral to membrane transferase activity, transferring glycosyl groups
217977_at	0.839	9.379	4.359	5.441e-04	0.050	-0.025	SEPX1	selenoprotein X, 1	16	-1928234	NM_016332	51734	16p13.3	Hs.655346	11	protein-methionine-R-oxide reductase activity cellular_component nucleus cytoplasm peptide-methionine-(S)-S-oxide reductase activity zinc ion binding selenium binding oxidoreductase activity protein repair metal ion binding oxidation reduction
201471_s_at	-0.458	9.615	-4.358	5.450e-04	0.050	-0.026	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	NM_003900	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
205181_at	0.515	6.308	4.355	5.482e-04	0.050	-0.032	ZNF193	zinc finger protein 193	6	28301051	NM_006299	7746	6p21.3	Hs.100921	8	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
235729_at	0.869	5.930	4.354	5.494e-04	0.050	-0.034	ZNF514	zinc finger protein 514	2	-95177126	T93113	84874	2q11.1	Hs.655109	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201298_s_at	-0.446	7.583	-4.354	5.494e-04	0.050	-0.034	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	2	-74236718	BC003398	55233	2p13.1	Hs.196437	12	protein binding zinc ion binding metal ion binding
208666_s_at	-0.624	8.509	-4.353	5.503e-04	0.050	-0.035	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22	-39550546	BE866412	6767	22q13.2	Hs.712713	29	binding cytoplasm protein folding protein binding, bridging
239043_at	0.887	3.229	4.353	5.506e-04	0.050	-0.036	ZNF404	zinc finger protein 404	19	-49068354	AA084273	342908	19q13.31	Hs.76561	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224367_at	2.962	6.783	4.352	5.516e-04	0.050	-0.037	BEX2	brain expressed X-linked 2	X	-102450929	AF251053	84707	Xq22	Hs.398989	11	nucleus cytoplasm
222736_s_at	-0.703	6.886	-4.345	5.595e-04	0.051	-0.051	TMEM38B	transmembrane protein 38B	9	107496645	BC000049	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
208352_x_at	0.579	11.108	4.345	5.595e-04	0.051	-0.051	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_020479	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
214179_s_at	-0.585	10.811	-4.345	5.600e-04	0.051	-0.051	NFE2L1	nuclear factor (erythroid-derived 2)-like 1	17	43480684	H93013	4779	17q21.3	Hs.514284	20	transcription factor activity transcription cofactor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter heme biosynthetic process inflammatory response anatomical structure morphogenesis sequence-specific DNA binding protein dimerization activity
221493_at	-0.578	10.576	-4.345	5.603e-04	0.051	-0.052	TSPYL1	TSPY-like 1	6	-116704438	AL136629	7259	6q22-q23	Hs.458358 Hs.486292	11	molecular_function cellular_component intracellular nucleus nucleolus nucleosome assembly biological_process
212731_at	-0.727	8.864	-4.343	5.615e-04	0.051	-0.054	ANKRD46	ankyrin repeat domain 46	8	-101602175	U79297	157567	8q22.2	Hs.530199	5	membrane integral to membrane
217993_s_at	-0.551	9.801	-4.337	5.688e-04	0.051	-0.066	MAT2B	methionine adenosyltransferase II, beta	5	162862808, 162865162	NM_013283	27430	5q34-q35	Hs.54642	20	catalytic activity protein binding intracellular nucleus S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process metabolic process dTDP-4-dehydrorhamnose reductase activity extracellular polysaccharide biosynthetic process methionine adenosyltransferase complex methionine adenosyltransferase regulator activity methionine adenosyltransferase regulator activity	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
224443_at	1.088	6.229	4.337	5.689e-04	0.051	-0.066	C1orf97	chromosome 1 open reading frame 97	1	209622719	BC005997	84791	1q32.3	Hs.523932	4
204349_at	-0.474	6.528	-4.336	5.701e-04	0.051	-0.068	MED7	mediator complex subunit 7	5	-156498028, -156498028	BC005250	9443	5q33.3	Hs.279902 Hs.719330	15	transcription coactivator activity protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription regulator activity regulation of transcription
225911_at	1.238	4.528	4.335	5.714e-04	0.051	-0.070	NPNT	nephronectin	4	107036053	AL138410	255743	4q24	Hs.518921	5	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development membrane cell differentiation
204685_s_at	-1.766	7.048	-4.330	5.765e-04	0.051	-0.078	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	3	-10340706	R52647	491	3p25.3	Hs.268942	30	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding cytoplasm plasma membrane ATP biosynthetic process cation transport calcium ion transport sensory perception of sound metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances neuron differentiation	Calcium signaling pathway
218959_at	-0.536	7.426	-4.326	5.821e-04	0.052	-0.087	HOXC10	homeobox C10	12	52665212	NM_017409	3226	12q13.3	Hs.44276	13	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation proximal/distal pattern formation cyclin-dependent protein kinase activating kinase holoenzyme complex spinal cord motor neuron cell fate specification embryonic limb morphogenesis sequence-specific DNA binding neuromuscular process
230030_at	-2.177	4.863	-4.325	5.823e-04	0.052	-0.088	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	X	-131587718	AI767756	90161	Xq26.2	Hs.385956	7	sulfotransferase activity membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
229743_at	-0.396	6.571	-4.321	5.870e-04	0.052	-0.095	ZNF438	zinc finger protein 438	10	-31173572, -31173572	AI886666	220929	10p11.23-p11.22	Hs.660642	6	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
223082_at	1.054	8.513	4.319	5.897e-04	0.052	-0.099	SH3KBP1	SH3-domain kinase binding protein 1	X	-19462003, -19462003	AF230904	30011	Xp22.1-p21.3	Hs.719268	58	molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse	Endocytosis
237116_at	-0.946	7.747	-4.319	5.897e-04	0.052	-0.099	LOC646903	hypothetical LOC646903	3		AI262277	646903	3q25.1	Hs.632559	1
226488_at	0.500	7.508	4.318	5.913e-04	0.052	-0.102	RCCD1	RCC1 domain containing 1	15	89299109	AW007826	91433	15q26.1	Hs.655895	4
228302_x_at	0.362	3.618	4.318	5.917e-04	0.052	-0.103	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	1	-20681470	AW162846	55450	1p36.12	Hs.197922	4	plasma membrane calcium-dependent protein kinase inhibitor activity postsynaptic density synaptosome protein kinase binding cell junction dendrite cell soma synapse postsynaptic membrane
200655_s_at	-0.458	10.516	-4.316	5.930e-04	0.052	-0.105	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	NM_006888	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
226024_at	0.408	8.761	4.315	5.945e-04	0.052	-0.107	COMMD1	copper metabolism (Murr1) domain containing 1	2	61986306	BG481459	150684	2p15	Hs.468702	28	nucleus cytoplasm identical protein binding
226651_at	-1.054	7.921	-4.314	5.957e-04	0.052	-0.109	HOMER1	homer homolog 1 (Drosophila)	5	-78705541	AW052119	9456	5q14.2	Hs.591761	33	skeletal muscle contraction protein binding membrane fraction cytoplasm plasma membrane integral to plasma membrane activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway synaptic transmission postsynaptic density Z disc cell junction positive regulation of calcium ion transport via store-operated calcium channel activity costamere synapse postsynaptic membrane skeletal muscle fiber development
241813_at	-0.876	5.183	-4.313	5.972e-04	0.052	-0.111	MBD1	methyl-CpG binding domain protein 1	18	-46049213	BG252318	4152	18q21	Hs.405610	40	transcription factor activity transcription corepressor activity protein binding nucleus transcription from RNA polymerase II promoter zinc ion binding methyl-CpG binding negative regulation of transcription nuclear speck metal ion binding
212155_at	0.974	8.699	4.309	6.017e-04	0.052	-0.118	RNF187	ring finger protein 187	1	226741716	AA085748	149603	1q42.13	Hs.356377 Hs.679030	3
235261_at	-0.578	10.438	-4.308	6.028e-04	0.052	-0.120	UNC45B	unc-45 homolog B (C. elegans)	17	30498948	AI800785	146862	17q12	Hs.379636	4	binding multicellular organismal development muscle organ development cell differentiation
213019_at	-0.495	7.854	-4.305	6.068e-04	0.053	-0.126	RANBP6	RAN binding protein 6	9	-6001019, -6001018	AI123233	26953	9p24.1	Hs.167496 Hs.675725	5	binding nucleus cytoplasm protein transport
222446_s_at	0.523	5.510	4.304	6.078e-04	0.053	-0.128	BACE2	beta-site APP-cleaving enzyme 2	21	41461597	AF178532	25825	21q22.3	Hs.529408	42	aspartic-type endopeptidase activity membrane fraction protein modification process proteolysis membrane protein ectodomain proteolysis peptidase activity protein secretion membrane integral to membrane peptide hormone processing negative regulation of amyloid precursor protein biosynthetic process	Alzheimer's disease
1556136_at	-2.662	6.925	-4.302	6.111e-04	0.053	-0.133	MYLK4	myosin light chain kinase family, member 4	6	-2608861	BU675945	340156	6p25.2	Hs.127830	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
230623_x_at	-0.538	7.821	-4.301	6.120e-04	0.053	-0.134	USP28	ubiquitin specific peptidase 28	11	-113173806	AI609285	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
203180_at	0.887	5.729	4.299	6.140e-04	0.053	-0.137	ALDH1A3	aldehyde dehydrogenase 1 family, member A3	15	99237531	NM_000693	220	15q26.3	Hs.459538	8	optic cup morphogenesis involved in camera-type eye development aldehyde dehydrogenase [NAD(P)+] activity cytoplasm oxidoreductase activity nucleus accumbens development retinoic acid metabolic process retinal metabolic process protein homodimerization activity positive regulation of apoptosis embryonic eye morphogenesis oxidation reduction olfactory pit development	Glycolysis / Gluconeogenesis Histidine metabolism Tyrosine metabolism Phenylalanine metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
233461_x_at	0.836	5.286	4.297	6.174e-04	0.053	-0.142	ZNF226	zinc finger protein 226	19	49361088, 49361088, 49361096, 49361156	AK023091	7769	19q13.2	Hs.145956	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213238_at	0.487	5.264	4.293	6.214e-04	0.053	-0.148	ATP10D	ATPase, class V, type 10D	4	47182166	AI478147	57205	4p12	Hs.437241	4	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
214681_at	0.300	4.794	4.293	6.214e-04	0.053	-0.148	GK	glycerol kinase	X	30581396	AI830490	2710	Xp21.3	Hs.1466	20	nucleotide binding glycerol kinase activity glycerol kinase activity ATP binding cytoplasm mitochondrion mitochondrial outer membrane cytosol carbohydrate metabolic process glycerol-3-phosphate metabolic process membrane transferase activity	Glycerolipid metabolism Metabolic pathways PPAR signaling pathway
224276_at	0.486	3.695	4.291	6.245e-04	0.053	-0.153	ZNF33A	zinc finger protein 33A	10	38339583	AF063599	7581	10p11.2	Hs.435774	8	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231666_at	-0.894	5.277	-4.289	6.267e-04	0.053	-0.156	PAX3	paired box 3	2	-222866592, -222774675, -222772850	AA194168	5077	2q35 2q35-q37	Hs.42146	103	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter apoptosis multicellular organismal development sensory perception of sound organ morphogenesis sequence-specific DNA binding
1560145_at	-0.482	5.884	-4.287	6.299e-04	0.054	-0.161	MKLN1	muskelin 1, intracellular mediator containing kelch motifs	7	130445394, 130663134	BQ942131	4289	7q32	Hs.44693	13	protein binding cytoplasm signal transduction
218330_s_at	1.036	5.815	4.285	6.316e-04	0.054	-0.163	NAV2	neuron navigator 2	11	19328846, 19691456, 20001211	NM_018162	89797	11p15.1	Hs.502116 Hs.551898 Hs.639427 Hs.639428	18	nucleotide binding helicase activity ATP binding nucleus nucleolus cytoplasm hydrolase activity
217843_s_at	-0.504	7.886	-4.285	6.319e-04	0.054	-0.164	MED4	mediator complex subunit 4	13	-47548092	NM_014166	29079	13q14.2	Hs.181112	21	transcription cofactor activity receptor activity protein binding nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription activator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription thyroid hormone receptor binding
239178_at	0.677	2.287	4.283	6.343e-04	0.054	-0.167	FGF9	fibroblast growth factor 9 (glia-activating factor)	13	21143214	AL583692	2254	13q11-q12	Hs.111	33	angiogenesis osteoblast differentiation positive regulation of mesenchymal cell proliferation chondrocyte differentiation extracellular region extracellular region extracellular space protein import into nucleus signal transduction cell-cell signaling growth factor activity heparin binding male gonad development negative regulation of Wnt receptor signaling pathway male sex determination lung development embryonic limb morphogenesis positive regulation of vascular endothelial growth factor receptor signaling pathway inner ear morphogenesis positive regulation of MAPKKK cascade positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of smoothened signaling pathway regulation of timing of cell differentiation embryonic gut development embryonic skeletal system development positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
209142_s_at	-0.886	10.214	-4.282	6.358e-04	0.054	-0.169	UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	17	-4119260	BC002775	7326	17p13.2 1q42	Hs.714345	12	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
203049_s_at	-0.581	8.672	-4.274	6.463e-04	0.054	-0.185	TTC37	tetratricopeptide repeat domain 37	5	-94825877	NM_014639	9652	5q15	Hs.482868	4	binding	RNA degradation
203799_at	0.776	5.586	4.273	6.480e-04	0.055	-0.187	CD302	CD302 molecule	2	-160333386	NM_014880	9936	2q24.2	Hs.130014	9	binding sugar binding membrane integral to membrane
210619_s_at	1.255	6.791	4.270	6.514e-04	0.055	-0.192	HYAL1	hyaluronoglucosaminidase 1	3	-50312324, -50312323, -50312323	AF173154	3373	3p21.3-p21.2	Hs.75619	30	hyalurononglucosaminidase activity extracellular region extracellular space lysosome carbohydrate metabolic process metabolic process hydrolase activity, acting on glycosyl bonds glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways
1565162_s_at	2.041	4.909	4.270	6.515e-04	0.055	-0.192	MGST1	microsomal glutathione S-transferase 1	12	16391342, 16391845, 16391978, 16397617	D16947	4257	12p12.3-p12.1	Hs.389700	22	glutathione transferase activity mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum microsome glutathione metabolic process membrane transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
209397_at	0.689	8.992	4.263	6.607e-04	0.055	-0.205	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	18	46659432	BC000147	4200	18q21 6p25-p24	Hs.233119	24	malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide
201227_s_at	0.438	10.740	4.263	6.611e-04	0.055	-0.206	NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	10	-102273486	NM_005004	4714	10q23.2-q23.33	Hs.523215	16	NADH dehydrogenase activity mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I endoplasmic reticulum mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
223170_at	0.398	5.297	4.263	6.612e-04	0.055	-0.206	TMEM98	transmembrane protein 98	17	28279040	AF132000	26022	17q11.2	Hs.3447	8	endoplasmic reticulum membrane integral to membrane
201994_at	-0.456	11.098	-4.262	6.629e-04	0.055	-0.208	MORF4L2	mortality factor 4 like 2	X	-102817083, -102817083	NM_012286	9643	Xq22	Hs.326387 Hs.441076 Hs.597035	19	regulation of cell growth molecular_function protein binding nucleus nucleolus DNA repair response to DNA damage stimulus chromatin modification regulation of transcription
226921_at	-0.770	8.092	-4.261	6.635e-04	0.055	-0.209	UBR1	ubiquitin protein ligase E3 component n-recognin 1	15	-41022389	AV715153	197131	15q13	Hs.591121	21	ubiquitin ligase complex proteasome complex ubiquitin-protein ligase activity protein binding cytoplasm cytosol ubiquitin-dependent protein catabolic process zinc ion binding ligase activity protein catabolic process metal ion binding
212861_at	-0.451	6.426	-4.261	6.639e-04	0.055	-0.210	MFSD5	major facilitator superfamily domain containing 5	12	51932146	BF690150	84975	12q13.13	Hs.654660	7	transport membrane integral to membrane
37965_at	0.557	6.330	4.259	6.657e-04	0.055	-0.212	PARVB	parvin, beta	22	42726505, 42751500	AA181053	29780	22q13.2-q13.33	Hs.475074	18	actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion cell junction	Focal adhesion
203132_at	-0.815	7.917	-4.259	6.669e-04	0.055	-0.214	RB1	retinoblastoma 1	13	47775883	NM_000321	5925	13q14.2	Hs.408528	525	cell cycle checkpoint regulation of transcription of G1/S-phase of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter M phase chromatin transcription factor activity transcription coactivator activity nucleus nucleoplasm spindle chromatin remodeling negative regulation of protein kinase activity cell cycle arrest transcription factor binding negative regulation of cell proliferation SWI/SNF complex transcription repressor activity PML body kinase binding negative regulation of cell growth androgen receptor signaling pathway ubiquitin protein ligase binding Rb-E2F complex enucleate erythrocyte differentiation regulation of lipid kinase activity interspecies interaction between organisms myoblast differentiation regulation of transcription positive regulation of macrophage differentiation negative regulation of S phase of mitotic cell cycle negative regulation of cell cycle positive regulation of transcription from RNA polymerase II promoter androgen receptor binding striated muscle cell differentiation phosphoprotein binding cell division G1 phase	Cell cycle Pathways in cancer Pancreatic cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer
208215_x_at	0.476	5.327	4.256	6.705e-04	0.055	-0.219	DRD4	dopamine receptor D4	11	627304	NM_000797	1815	11p15.5	Hs.99922	339	activation of MAPK activity dopamine D4 receptor activity behavioral fear response response to amphetamine receptor activity G-protein coupled receptor activity protein binding plasma membrane integral to plasma membrane cellular calcium ion homeostasis signal transduction negative regulation of adenylate cyclase activity inhibition of adenylate cyclase activity by dopamine receptor signaling pathway drug binding adult locomotory behavior potassium channel regulator activity SH3 domain binding negative regulation of cAMP biosynthetic process positive regulation of sodium:hydrogen antiporter activity positive regulation of kinase activity response to histamine social behavior regulation of dopamine metabolic process behavioral response to cocaine behavioral response to ethanol arachidonic acid secretion negative regulation of protein secretion positive regulation of dopamine uptake negative regulation of calcium ion transport via voltage-gated calcium channel activity regulation of inhibitory postsynaptic membrane potential	Neuroactive ligand-receptor interaction
222154_s_at	-0.648	9.172	-4.254	6.724e-04	0.055	-0.222	SPATS2L	spermatogenesis associated, serine-rich 2-like	2	200878848, 200879229, 200879600	AK002064	26010	2q33.1	Hs.120323	9
212352_s_at	-0.532	10.051	-4.254	6.724e-04	0.055	-0.222	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	14	-74667923	BE780075	10972	14q24.3	Hs.74137	22	protein binding microsome ER-Golgi intermediate compartment Golgi apparatus cis-Golgi network protein transport membrane integral to membrane vesicle-mediated transport melanosome zymogen granule membrane regulated secretory pathway vesicle targeting, to, from or within Golgi
202432_at	-0.924	11.048	-4.254	6.725e-04	0.055	-0.222	PPP3CB	protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform	10	-74866569	NM_021132	5532	10q21-q22	Hs.500067	29	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding calcineurin complex signal transduction zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
209108_at	0.541	5.392	4.254	6.726e-04	0.055	-0.222	TSPAN6	tetraspanin 6	X	-99770450	AF053453	7105	Xq22	Hs.43233	10	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
1552767_a_at	-2.143	5.544	-4.254	6.728e-04	0.055	-0.222	HS6ST2	heparan sulfate 6-O-sulfotransferase 2	X	-131587718	NM_147174	90161	Xq26.2	Hs.385956	7	sulfotransferase activity membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
223299_at	0.425	7.028	4.254	6.737e-04	0.055	-0.223	SEC11C	SEC11 homolog C (S. cerevisiae)	18	54958104	AF212233	90701	18q21.32	Hs.45107	2	endoplasmic reticulum microsome signal peptide processing proteolysis peptidase activity membrane integral to membrane	Protein export
213327_s_at	-0.504	6.620	-4.253	6.741e-04	0.055	-0.224	USP12	ubiquitin specific peptidase 12	13	-26540437	AI820101	219333	13q12.13	Hs.42400	6	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding cellular_component protein modification process ubiquitin-dependent protein catabolic process peptidase activity protein deubiquitination
218084_x_at	0.466	6.036	4.253	6.750e-04	0.055	-0.225	FXYD5	FXYD domain containing ion transport regulator 5	19	40337466	NM_014164	53827	19q12-q13.1	Hs.333418	20	actin binding ion channel activity ion transport membrane integral to membrane microvillus assembly cadherin binding negative regulation of calcium-dependent cell-cell adhesion
214901_at	0.528	5.371	4.251	6.768e-04	0.055	-0.228	ZNF8	zinc finger protein 8	19	63482129	AI671579	7554	19q13.43	Hs.590941 Hs.713519	8	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding BMP signaling pathway metal ion binding
204198_s_at	0.405	3.687	4.251	6.775e-04	0.055	-0.229	RUNX3	runt-related transcription factor 3	1	-25098588, -25098588	AA541630	864	1p36	Hs.170019	95	transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter induction of apoptosis cell proliferation negative regulation of cell cycle negative regulation of epithelial cell proliferation
206542_s_at	-0.735	8.391	-4.246	6.842e-04	0.055	-0.238	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	AV725365	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
224394_at	-0.541	4.431	-4.245	6.849e-04	0.055	-0.239	RNF7	ring finger protein 7	3	142939740	AF312226	9616	3q22-q24	Hs.134623	25	copper ion binding protein binding nucleus cytoplasm anti-apoptosis redox signal response zinc ion binding induction of apoptosis by oxidative stress NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation metal ion binding	Ubiquitin mediated proteolysis
202641_at	0.478	6.960	4.245	6.861e-04	0.055	-0.240	ARL3	ADP-ribosylation factor-like 3	10	-104423477	NM_004311	403	10q23.3	Hs.182215	18	nucleotide binding magnesium ion binding GTP binding intracellular nucleus Golgi apparatus spindle cell cycle small GTPase mediated signal transduction membrane cell division
209278_s_at	1.893	4.644	4.244	6.866e-04	0.055	-0.241	TFPI2	tissue factor pathway inhibitor 2	7	-93353680	L27624	7980	7q22	Hs.438231	63	serine-type endopeptidase inhibitor activity extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix blood coagulation peptidase inhibitor activity
221412_at	0.431	4.247	4.244	6.870e-04	0.055	-0.242	VN1R1	vomeronasal 1 receptor 1	19	-62658353	NM_020633	57191	19q13.4	Hs.388810 Hs.677423	9	receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane pheromone receptor activity response to pheromone
225333_at	0.398	4.335	4.243	6.886e-04	0.055	-0.244	ZNF496	zinc finger protein 496	1	-245530244	AI218383	84838	1q44	Hs.654803	5	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212927_at	-0.680	6.316	-4.241	6.908e-04	0.055	-0.247	SMC5	structural maintenance of chromosomes 5	9	72063697	AB011166	23137	9q21.12	Hs.534189 Hs.601181	13	nucleotide binding ATP binding nucleus chromosome DNA repair DNA recombination response to DNA damage stimulus
57588_at	-1.384	8.282	-4.241	6.913e-04	0.055	-0.247	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	20	19141289	R62432	57419	20p13	Hs.654790	2	calcium ion binding ion transport potassium ion transport sodium ion transport calcium ion transport calcium, potassium:sodium antiporter activity symporter activity antiporter activity membrane integral to membrane potassium ion binding sodium ion binding
230367_at	-2.330	9.957	-4.240	6.925e-04	0.055	-0.249	SMTNL1	smoothelin-like 1	11	57065554	AI359511	219537	11q12.1	Hs.68756	2	response to activity peptidyl-serine phosphorylation M band I band response to drug contractile fiber positive regulation of vasoconstriction negative regulation of vasodilation muscle organ morphogenesis
238441_at	-0.858	9.214	-4.238	6.951e-04	0.055	-0.252	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	AI928203	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
204068_at	-0.432	6.685	-4.237	6.967e-04	0.055	-0.255	STK3	serine/threonine kinase 3 (STE20 homolog, yeast)	8	-99536036	NM_006281	6788	8q22.2	Hs.492333	22	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction protein kinase cascade transferase activity positive regulation of apoptosis protein dimerization activity	MAPK signaling pathway
202313_at	-0.346	8.633	-4.234	7.017e-04	0.056	-0.261	PPP2R2A	protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform	8	26204950	NM_002717	5520	8p21.2	Hs.146339	44	protein phosphatase type 2A complex protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation signal transduction protein phosphatase type 2A regulator activity response to morphine	Tight junction
229843_at	-0.519	2.935	-4.229	7.078e-04	0.056	-0.269	FAM82B	family with sequence similarity 82, member B	8	-87553693	BE962867	51115	8q21.3	Hs.145386	5	binding cytoplasm microtubule
1555516_at	-0.643	3.965	-4.229	7.082e-04	0.056	-0.270	FOXP2	forkhead box P2	7	113842287	BC018016	93986	7q31	Hs.656280	50	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding caudate nucleus development putamen development protein homodimerization activity sequence-specific DNA binding metal ion binding
224415_s_at	0.495	9.434	4.228	7.090e-04	0.056	-0.271	HINT2	histidine triad nucleotide binding protein 2	9	-35802956	AF356515	84681	9p13.3	Hs.70573	6	extracellular region mitochondrion hydrolase activity
203238_s_at	0.478	5.554	4.228	7.101e-04	0.056	-0.272	NOTCH3	Notch homolog 3 (Drosophila)	19	-15131443	NM_000435	4854	19p13.2-p13.1	Hs.8546	96	receptor activity calcium ion binding protein binding nucleus plasma membrane Notch signaling pathway multicellular organismal development integral to membrane forebrain development regulation of transcription negative regulation of neuron differentiation neuron fate commitment regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
231569_at	0.396	3.402	4.228	7.103e-04	0.056	-0.273	TMEM31	transmembrane protein 31	X	102852492	N58489	203562	Xq22.2	Hs.98843	1	membrane integral to membrane
213698_at	0.583	5.844	4.226	7.120e-04	0.056	-0.275	ZMYM6	zinc finger, MYM-type 6	1	-35224353	AI805560	9204	1p34.2	Hs.533986 Hs.623978 Hs.675613	8	DNA binding nucleus nucleolus multicellular organismal development zinc ion binding metal ion binding
235848_x_at	-0.859	8.032	-4.226	7.120e-04	0.056	-0.275	ATL2	atlastin GTPase 2	2	-38375534	N35250	64225	2p22.2-p22.1	Hs.594950	8	nucleotide binding GTPase activity GTP binding membrane integral to membrane
228810_at	-0.658	5.632	-4.224	7.154e-04	0.056	-0.279	CCNYL1	cyclin Y-like 1	2	208284508	AW135279	151195	2q33.3	Hs.471234 Hs.597952	5
225342_at	0.951	5.487	4.224	7.156e-04	0.056	-0.279	AK3L1	adenylate kinase 3-like 1	1	65385819, 65386100, 65386473	AK026966	205	1p31.3	Hs.10862 Hs.592601	10	nucleotide binding adenylate kinase activity ATP binding GTP binding mitochondrion mitochondrial matrix nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity	Purine metabolism Metabolic pathways
213793_s_at	-0.991	8.633	-4.223	7.171e-04	0.056	-0.281	HOMER1	homer homolog 1 (Drosophila)	5	-78705541	BE550452	9456	5q14.2	Hs.591761	33	skeletal muscle contraction protein binding membrane fraction cytoplasm plasma membrane integral to plasma membrane activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway synaptic transmission postsynaptic density Z disc cell junction positive regulation of calcium ion transport via store-operated calcium channel activity costamere synapse postsynaptic membrane skeletal muscle fiber development
216526_x_at	0.772	9.841	4.220	7.207e-04	0.056	-0.286	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	AK024836	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
238149_at	0.604	2.307	4.217	7.252e-04	0.056	-0.292	ZNF818P	zinc finger protein 818 pseudogene	19		AI651641	390963	19q13.42	Hs.444446		DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203525_s_at	-0.789	7.366	-4.217	7.255e-04	0.056	-0.292	APC	adenomatous polyposis coli	5	112071116, 112101454	AI375486	324	5q21-q22	Hs.158932	386	cytokinesis after mitosis kinetochore kidney development hair follicle development nucleus cytoplasm centrosome cytosol cytoplasmic microtubule protein complex assembly response to DNA damage stimulus negative regulation of microtubule depolymerization cell cycle arrest mitotic metaphase/anaphase transition mitotic cell cycle spindle assembly checkpoint axonogenesis beta-catenin binding microtubule binding axis specification anterior/posterior pattern formation dorsal/ventral pattern formation proximal/distal pattern formation lateral plasma membrane protein kinase regulator activity protein kinase binding negative regulation of Wnt receptor signaling pathway positive regulation of cell migration growth cone positive regulation of epithelial cell differentiation beta-catenin destruction complex positive regulation of microtubule polymerization cell projection membrane positive regulation of pseudopodium assembly T cell differentiation in the thymus axon part Axin-APC-beta-catenin-GSK3B complex somatic stem cell maintenance negative regulation of odontogenesis cell projection positive regulation of apoptosis negative regulation of apoptosis negative regulation of MAPKKK cascade skin development regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process negative regulation of cyclin-dependent protein kinase activity positive regulation of cell adhesion muscle maintenance thymus development negative regulation of epithelial cell proliferation regulation of nitrogen compound metabolic process chromosome organization regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye Wnt receptor signaling pathway through beta-catenin Wnt receptor signaling pathway through beta-catenin	Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma
217828_at	-0.554	8.005	-4.214	7.295e-04	0.056	-0.297	SLTM	SAFB-like, transcription modulator	15	-56958535	NM_024755	79811	15q22.1	Hs.512932	3	nucleotide binding RNA binding nucleus apoptosis regulation of transcription
226531_at	-1.067	7.220	-4.213	7.317e-04	0.056	-0.300	ORAI1	ORAI calcium release-activated calcium modulator 1	12	120548837	AL530596	84876	12q24.31	Hs.55148	56	ion channel activity calcium ion binding protein binding plasma membrane integral to plasma membrane ion transport immune response store-operated calcium channel activity positive regulation of calcium ion transport
202174_s_at	-0.569	9.124	-4.209	7.379e-04	0.057	-0.308	PCM1	pericentriolar material 1	8	17824645	NM_006197	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
222991_s_at	-0.639	7.157	-4.208	7.388e-04	0.057	-0.309	UBQLN1	ubiquilin 1	9	-85464697	AL136643	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
215464_s_at	0.563	6.211	4.206	7.416e-04	0.057	-0.313	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	17	-3512937	AK001327	30851	17p13	Hs.12956	14	nucleus cytoplasm Rho protein signal transduction beta-catenin binding negative regulation of cell proliferation negative regulation of Wnt receptor signaling pathway transcription regulator activity
209323_at	-0.524	8.357	-4.205	7.440e-04	0.057	-0.316	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	11	-75738651	AF081567	5612	11q13.5	Hs.503315	12	DNA binding nucleus nucleolus response to stress signal transduction zinc ion binding negative regulation of cell proliferation metal ion binding protein dimerization activity
219457_s_at	0.447	5.367	4.204	7.448e-04	0.057	-0.317	RIN3	Ras and Rab interactor 3	14	92049877	NM_024832	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
215175_at	0.519	5.740	4.204	7.455e-04	0.057	-0.317	PCNX	pecanex homolog (Drosophila)	14	70443874	AB023212	22990	14q24.2	Hs.446559	10	membrane integral to membrane
205741_s_at	0.509	9.024	4.200	7.511e-04	0.057	-0.324	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	NM_001392	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
229452_at	0.491	7.104	4.200	7.513e-04	0.057	-0.325	TMEM88	transmembrane protein 88	17	7699108	AL544576	92162	17p13.1	Hs.389669	2	membrane integral to membrane
225908_at	0.390	8.659	4.199	7.532e-04	0.057	-0.327	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	2	9532120	AI829927	285148	2p25.1	Hs.614939	2	lipid catabolic process hydrolase activity, acting on ester bonds
225053_at	-0.462	10.293	-4.197	7.555e-04	0.057	-0.330	CNOT7	CCR4-NOT transcription complex, subunit 7	8	-17133392, -17131110	W94952	29883	8p22-p21.3	Hs.645009 Hs.719129	19	nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter	RNA degradation
1553102_a_at	-0.637	8.649	-4.197	7.560e-04	0.057	-0.331	CCDC69	coiled-coil domain containing 69	5	-150540805	BC016647	26112	5q33.1	Hs.655336	3
209061_at	-0.686	7.687	-4.194	7.603e-04	0.057	-0.336	NCOA3	nuclear receptor coactivator 3	20	45564063	AI761748	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
211654_x_at	0.502	6.355	4.194	7.609e-04	0.057	-0.337	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M17565	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
203662_s_at	-0.690	9.137	-4.192	7.636e-04	0.058	-0.340	TMOD1	tropomodulin 1	9	99326257	NM_003275	7111	9q22.3	Hs.494595	18	actin binding tropomyosin binding nucleus cytoplasm membrane myofibril myofibril assembly cortical cytoskeleton
201079_at	-0.666	9.237	-4.188	7.697e-04	0.058	-0.347	SYNGR2	synaptogyrin 2	17	73676265	NM_004710	9144	17q25.3	Hs.464210 Hs.708616	5	integral to plasma membrane membrane
219873_at	0.363	5.007	4.186	7.730e-04	0.058	-0.351	COLEC11	collectin sub-family member 11	2	3620511	NM_024027	78989	2p25.3	Hs.32603	3	binding calcium ion binding sugar binding mannose binding extracellular region
209032_s_at	0.696	6.063	4.186	7.731e-04	0.058	-0.351	CADM1	cell adhesion molecule 1	11	-114549554	AF132811	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
200923_at	0.832	5.659	4.184	7.767e-04	0.058	-0.356	LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	17	-74478930	NM_005567	3959	17q25	Hs.514535	36	scavenger receptor activity protein binding extracellular region proteinaceous extracellular matrix extracellular space nucleus cellular defense response cell adhesion signal transduction membrane
218172_s_at	-0.858	5.866	-4.183	7.777e-04	0.058	-0.357	DERL1	Der1-like domain family, member 1	8	-124094748	NM_018630	79139	8q24.13	Hs.241576	28	receptor activity protein binding endoplasmic reticulum endoplasmic reticulum response to unfolded protein protein transport membrane integral to membrane intracellular transport of viral proteins in host cell integral to endoplasmic reticulum membrane ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol MHC class I protein binding interspecies interaction between organisms	Amyotrophic lateral sclerosis (ALS)
201238_s_at	-0.728	10.394	-4.181	7.816e-04	0.058	-0.361	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	7	116289798	BC005338	830	7q31.2-q31.3	Hs.446123	14	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
233647_s_at	0.531	6.259	4.178	7.855e-04	0.058	-0.366	CDADC1	cytidine and dCMP deaminase domain containing 1	13	48720103	AL138875	81602	13q14.2	Hs.388220	2	zinc ion binding hydrolase activity metal ion binding
1553961_s_at	0.653	6.769	4.178	7.864e-04	0.058	-0.367	SNX21	sorting nexin family member 21	20	43895876	CA447177	90203	20q13.12	Hs.472854	8	protein binding cell communication protein transport phosphoinositide binding
212573_at	-0.622	8.451	-4.175	7.906e-04	0.058	-0.372	ENDOD1	endonuclease domain containing 1	11	94462664	AF131747	23052	11q21	Hs.167115	6	nucleic acid binding endonuclease activity extracellular region hydrolase activity metal ion binding	Apoptosis
207145_at	-0.885	4.700	-4.175	7.907e-04	0.058	-0.372	MSTN	myostatin	2	-190628670	NM_005259	2660	2q32.2	Hs.41565	55	cytokine activity extracellular region extracellular space transforming growth factor beta receptor signaling pathway muscle organ development growth factor activity growth positive regulation of transcription
205007_s_at	0.798	6.177	4.174	7.926e-04	0.058	-0.374	CIB2	calcium and integrin binding family member 2	15	-76184045	AI478592	10518	15q24	Hs.129867	6	calcium ion binding protein binding
223527_s_at	0.483	5.585	4.170	7.993e-04	0.059	-0.382	CDADC1	cytidine and dCMP deaminase domain containing 1	13	48720103	AL138875	81602	13q14.2	Hs.388220	2	zinc ion binding hydrolase activity metal ion binding
219656_at	0.369	6.482	4.169	7.995e-04	0.059	-0.383	PCDH12	protocadherin 12	5	-141304713	NM_016580	51294	5q31	Hs.439474	10	calcium ion binding protein binding plasma membrane integral to plasma membrane cell-cell junction cell adhesion homophilic cell adhesion neuron recognition calcium-dependent cell-cell adhesion
208949_s_at	0.622	9.829	4.169	7.999e-04	0.059	-0.383	LGALS3	lectin, galactoside-binding, soluble, 3	14	54665624, 54673658	BC001120	3958	14q21-q22	Hs.531081	162	skeletal system development protein binding sugar binding proteinaceous extracellular matrix nucleus cytoplasm plasma membrane IgE binding cell differentiation extracellular matrix organization
222735_at	-0.765	9.485	-4.168	8.021e-04	0.059	-0.386	TMEM38B	transmembrane protein 38B	9	107496645	AW452608	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
238497_at	0.359	3.491	4.167	8.034e-04	0.059	-0.387	TMEM136	transmembrane protein 136	11	119701225	N51836	219902	11q23.3	Hs.706896	1	membrane integral to membrane
1552701_a_at	0.635	4.232	4.166	8.050e-04	0.059	-0.389	CARD16	caspase recruitment domain family, member 16	11	-104417262	NM_052889	114769		Hs.348365	8	cysteine-type endopeptidase activity cysteine-type endopeptidase inhibitor activity protein binding intracellular proteolysis peptidase inhibitor activity regulation of apoptosis
201661_s_at	-0.717	9.035	-4.164	8.086e-04	0.059	-0.393	ACSL3	acyl-CoA synthetase long-chain family member 3	2	223433975	NM_004457	2181	2q34-q35	Hs.655772	20	nucleotide binding magnesium ion binding fatty-acyl-CoA synthase activity long-chain-fatty-acid-CoA ligase activity protein binding ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
225243_s_at	-0.761	8.469	-4.162	8.118e-04	0.059	-0.397	SLMAP	sarcolemma associated protein	3	57718213	AB046821	7871	3p21.2-p14.3	Hs.476432	11	smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding
212993_at	-0.486	7.263	-4.161	8.138e-04	0.059	-0.399	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	9	-138043023	AA114166	138151	9q34.3	Hs.112895	3	protein binding nucleus positive regulation of cell proliferation negative regulation of transcription specific transcriptional repressor activity nuclear body protein homooligomerization
204979_s_at	-0.447	11.743	-4.161	8.140e-04	0.059	-0.399	SH3BGR	SH3 domain binding glutamic acid-rich protein	21	39739666, 39745649	NM_007341	6450	21q22.3	Hs.473847	8	SH3/SH2 adaptor activity cytosol protein complex assembly SH3 domain binding
214022_s_at	0.839	8.409	4.160	8.143e-04	0.059	-0.400	IFITM1	interferon induced transmembrane protein 1 (9-27)	11	303990	AA749101	8519	11p15.5	Hs.458414	16	receptor signaling protein activity protein binding plasma membrane cell surface receptor linked signal transduction negative regulation of cell proliferation response to biotic stimulus integral to membrane	B cell receptor signaling pathway
223598_at	-0.672	9.548	-4.159	8.160e-04	0.059	-0.402	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	AF262027	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
226206_at	-0.601	8.209	-4.158	8.183e-04	0.059	-0.404	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	7	1536893	BG231691	7975	7p22.3	Hs.520612	14	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent nervous system development sequence-specific DNA binding
202808_at	-0.599	7.423	-4.158	8.187e-04	0.059	-0.405	C10orf26	chromosome 10 open reading frame 26	10	104493716, 104525877	AK000161	54838	10q24.32	Hs.500897 Hs.693257 Hs.707763	9	membrane integral to membrane
204663_at	0.409	7.408	4.157	8.199e-04	0.059	-0.406	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	11	-85829799, -85829797, -85829797	NM_006680	10873	11cen-q22.3	Hs.199743	8	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity mitochondrion mitochondrial matrix pyruvate metabolic process malate metabolic process oxygen and reactive oxygen species metabolic process aerobic respiration oxidoreductase activity metal ion binding cofactor binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways
213279_at	0.522	5.807	4.156	8.221e-04	0.059	-0.408	DHRS1	dehydrogenase/reductase (SDR family) member 1	14	-23829645, -23829645	AL050217	115817	14q12	Hs.719146	13	binding nucleus cytoplasm mitochondrial inner membrane endoplasmic reticulum Golgi apparatus oxidoreductase activity oxidation reduction
1554168_a_at	1.040	7.854	4.155	8.235e-04	0.059	-0.410	SH3KBP1	SH3-domain kinase binding protein 1	X	-19462003, -19462003	AF542051	30011	Xp22.1-p21.3	Hs.719268	58	molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse	Endocytosis
217980_s_at	0.386	9.327	4.154	8.244e-04	0.059	-0.411	MRPL16	mitochondrial ribosomal protein L16	11	-59330183	NM_017840	54948	11q12-q13.1	Hs.530734	7	structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation
212610_at	-0.581	10.103	-4.154	8.250e-04	0.059	-0.412	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	U79291	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
209356_x_at	0.492	6.281	4.149	8.337e-04	0.060	-0.421	EFEMP2	EGF-containing fibulin-like extracellular matrix protein 2	11	-65390487	AB030655	30008	11q13.1	Hs.170622	15	transmembrane receptor activity extracellular matrix structural constituent calcium ion binding protein binding extracellular region basement membrane blood coagulation membrane
211382_s_at	-0.597	9.133	-4.148	8.350e-04	0.060	-0.423	TACC2	transforming, acidic coiled-coil containing protein 2	10	123738678, 123913094	AF220152	10579	10q26	Hs.501252 Hs.713875	18	protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding
207417_s_at	0.615	3.952	4.146	8.385e-04	0.060	-0.427	ZNF177	zinc finger protein 177	19	9334695	NM_003451	7730	19p13.2	Hs.172979	4	negative regulation of transcription from RNA polymerase II promoter DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226822_at	0.563	5.658	4.146	8.388e-04	0.060	-0.427	STOX2	storkhead box 2	4	185063502	AL512713	56977	4q35.1	Hs.21958 Hs.696657	3
239462_at	0.460	5.274	4.145	8.401e-04	0.060	-0.429	ZNF284	zinc finger protein 284	19	49268136	AI559740	342909	19q13.31	Hs.279840 Hs.445395	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
236574_at	0.320	5.748	4.143	8.437e-04	0.060	-0.433	LOC284373	hypothetical protein LOC284373	19		AI304870	284373	19q13.41	Hs.188680	1
217122_s_at	-0.497	7.810	-4.141	8.464e-04	0.060	-0.436	RP11-345P4.4	similar to solute carrier family 35, member E2	1	-1582801	AL031282	728661	1p36.33	Hs.655255	6	membrane integral to membrane
219632_s_at	0.632	5.676	4.140	8.484e-04	0.060	-0.438	TRPV1	transient receptor potential cation channel, subfamily V, member 1	17	-3415489, -3415489, -3415489, -3415489	AF196175	7442	17p13.2	Hs.579217 Hs.655380	107	nucleotide binding ion channel activity calcium channel activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ion transport calcium ion transport cell surface receptor linked signal transduction chemosensory behavior thermoception	Neuroactive ligand-receptor interaction
216887_s_at	-0.715	11.269	-4.129	8.683e-04	0.061	-0.459	LDB3	LIM domain binding 3	10	88418300, 88418405, 88418405	AJ133768	11155	10q22.3-q23.2	Hs.657271	15	protein binding cytoplasm cytoskeleton zinc ion binding Z disc pseudopodium metal ion binding perinuclear region of cytoplasm
225268_at	-0.618	10.637	-4.129	8.689e-04	0.061	-0.460	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	AU144710	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
227951_s_at	0.649	5.800	4.127	8.709e-04	0.061	-0.462	FAM98C	family with sequence similarity 98, member C	19	43585614	AW338561	147965	19q13.2	Hs.355162	2
226229_s_at	0.417	5.867	4.116	8.920e-04	0.062	-0.484	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	BF510732	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
203756_at	0.379	6.736	4.116	8.922e-04	0.062	-0.485	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	11	72697310	NM_014786	9828	11q13.4	Hs.533719 Hs.719521	8	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular actin cytoskeleton organization regulation of Rho protein signal transduction
202698_x_at	0.409	12.077	4.115	8.927e-04	0.062	-0.485	COX4I1	cytochrome c oxidase subunit IV isoform 1	16	84390696	NM_001861	1327	16q22-qter	Hs.433419	17	cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
202693_s_at	-0.725	5.990	-4.114	8.947e-04	0.062	-0.487	STK17A	serine/threonine kinase 17a	7	43589216	AW194730	9263	7p12-p14	Hs.709489	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity
226679_at	0.519	6.465	4.113	8.966e-04	0.062	-0.489	SLC26A11	solute carrier family 26, member 11	17	75808831	BE964598	284129	17q25.3	Hs.4866	4	transporter activity endoplasmic reticulum Golgi apparatus plasma membrane ion transport secondary active sulfate transmembrane transporter activity sulfate transport anion transmembrane transporter activity anion exchanger activity integral to membrane
235259_at	-0.410	3.065	-4.113	8.966e-04	0.062	-0.489	PACRGL	PARK2 co-regulated-like	4	20311133	AA398590	133015	4p15.31	Hs.479298	5	binding
240289_at	-1.199	7.611	-4.112	8.992e-04	0.062	-0.492	LOC100131683	hypothetical protein LOC100131683	4		W86910	100131683	4q35.1	Hs.442702
236192_at	-0.397	5.637	-4.111	9.008e-04	0.062	-0.494	HOOK3	hook homolog 3 (Drosophila)	8	42871189	BF447112	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
226064_s_at	0.608	5.869	4.110	9.016e-04	0.062	-0.494	DGAT2	diacylglycerol O-acyltransferase homolog 2 (mouse)	11	75157425	AW469523	84649	11q13.5	Hs.334305	16	2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity membrane fraction endoplasmic reticulum glycerol metabolic process acyltransferase activity lipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process	Glycerolipid metabolism Retinol metabolism Metabolic pathways
224932_at	0.591	11.130	4.110	9.019e-04	0.062	-0.495	CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10	22	-22438020	AI814909	400916	22q11.23	Hs.66915	2	mitochondrion
226648_at	-0.539	6.811	-4.110	9.020e-04	0.062	-0.495	HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	10	102285630	AI769745	55662	10q24	Hs.500788	30	peptide-aspartate beta-dioxygenase activity iron ion binding protein binding nucleus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
241458_at	-0.372	4.612	-4.109	9.040e-04	0.062	-0.497	SETD2	SET domain containing 2	3	-47032903	AI868267	29072	3p21.31	Hs.517941	18	DNA binding protein binding nucleus methyltransferase activity oxidoreductase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription transition metal ion binding	Lysine degradation
33850_at	-0.445	8.659	-4.109	9.043e-04	0.062	-0.497	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	W28892	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
221994_at	-0.743	12.166	-4.108	9.057e-04	0.062	-0.499	PDLIM5	PDZ and LIM domain 5	4	95592060, 95592060	AA196325	10611	4q22	Hs.480311	34	actin binding protein kinase C binding protein binding membrane fraction cytosol zinc ion binding actin cytoskeleton Z disc actinin binding metal ion binding
200650_s_at	-1.054	12.298	-4.108	9.066e-04	0.062	-0.499	LDHA	lactate dehydrogenase A	11	18372511	NM_005566	3939	11p15.4	Hs.2795	46	L-lactate dehydrogenase activity protein binding cytoplasm cytosol oxidoreductase activity anaerobic glycolysis cellular carbohydrate metabolic process oxidation reduction	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways
227289_at	0.652	4.851	4.106	9.090e-04	0.063	-0.502	PCDH17	protocadherin 17	13	57103789	AU119437	27253	13q21.1	Hs.106511	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
239288_at	-1.380	6.386	-4.106	9.105e-04	0.063	-0.503	TNIK	TRAF2 and NCK interacting kinase	3	-172547417, -172262985	BF431017	23043	3q26.2-q26.31	Hs.34024	14	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade transferase activity
203477_at	0.688	9.302	4.105	9.123e-04	0.063	-0.505	COL15A1	collagen, type XV, alpha 1	9	100745958	NM_001855	1306	9q21-q22	Hs.409034	18	angiogenesis extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix collagen type XV cell adhesion multicellular organismal development cell differentiation
222679_s_at	-0.814	5.615	-4.104	9.129e-04	0.063	-0.506	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	3	-184143252	AW468880	54165	3q26.3	Hs.715661	16	molecular_function cellular_component biological_process modification-dependent protein catabolic process
212543_at	0.526	4.207	4.103	9.156e-04	0.063	-0.509	AIM1	absent in melanoma 1	6	107066422	U83115	202	6q21	Hs.643590 Hs.717199	12	molecular_function sugar binding cellular_component biological_process
58696_at	0.482	7.082	4.103	9.157e-04	0.063	-0.509	EXOSC4	exosome component 4	8	145205509	AL039469	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
218235_s_at	-0.666	10.276	-4.103	9.163e-04	0.063	-0.509	UTP11L	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)	1	38250970	NM_016037	51118	1p34.3	Hs.472038 Hs.637686	11	protein binding extracellular space nucleus nucleolus cytoplasm rRNA processing induction of apoptosis nervous system development small-subunit processome nerve growth factor receptor signaling pathway
225564_at	0.545	5.002	4.102	9.181e-04	0.063	-0.511	SPATA13	spermatogenesis associated 13	13	23632886	AW269397	221178	13q12.12	Hs.657121	7	Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
213955_at	-1.018	10.162	-4.100	9.219e-04	0.063	-0.515	MYOZ3	myozenin 3	5	150020596	BE673151	91977	5q33.1	Hs.91626	7	protein binding cytoplasm Z disc
201366_at	-0.559	9.200	-4.099	9.232e-04	0.063	-0.516	ANXA7	annexin A7	10	-74805194	NM_004034	310	10q21.1-q21.2	Hs.631827	24	calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding
225402_at	-0.684	4.989	-4.094	9.330e-04	0.063	-0.526	TP53RK	TP53 regulating kinase	20	-44746410	BG339450	112858	20q13.2	Hs.440263	12	nucleotide binding p53 binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity
226066_at	-0.504	8.536	-4.094	9.332e-04	0.063	-0.526	MITF	microphthalmia-associated transcription factor	3	69871322, 69895651, 69998131, 70010945, 70068442	AL117653	4286	3p14.2-p14.1	Hs.166017 Hs.618266	93	DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation	Melanogenesis Pathways in cancer Melanoma
1564063_a_at	-0.359	5.207	-4.093	9.342e-04	0.063	-0.527	ATP11B	ATPase, class VI, type 11B	3	183993984	AK093727	23200	3q27	Hs.478429	8	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding nuclear inner membrane ATP biosynthetic process ion transport metabolic process ion transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport aminophospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
217649_at	-0.459	3.697	-4.091	9.376e-04	0.063	-0.531	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AV702306	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
205444_at	-1.938	10.528	-4.090	9.405e-04	0.063	-0.534	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	16	28797309	NM_004320	487	16p12.1	Hs.657344	41	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding protein binding ATP binding microsome ATP biosynthetic process cation transport metabolic process apoptotic mitochondrial changes membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances positive regulation of fast-twitch skeletal muscle fiber contraction elevation of endoplasmic reticulum calcium ion concentration reduction of endoplasmic reticulum calcium ion concentration sarcoplasmic reticulum membrane sarcoplasmic reticulum membrane calcium channel complex response to endoplasmic reticulum stress protein homodimerization activity elevation of mitochondrial calcium ion concentration maintenance of mitochondrion location apoptosis in response to endoplasmic reticulum stress calcium ion import	Calcium signaling pathway Alzheimer's disease
204264_at	0.769	7.437	4.090	9.407e-04	0.063	-0.534	CPT2	carnitine palmitoyltransferase 2	1	53434688	NM_000098	1376	1p32	Hs.713535	53	carnitine O-palmitoyltransferase activity carnitine O-palmitoyltransferase activity mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport carnitine shuttle acyltransferase activity membrane transferase activity regulation of fatty acid oxidation	Fatty acid metabolism PPAR signaling pathway
209545_s_at	0.367	5.602	4.089	9.415e-04	0.063	-0.535	RIPK2	receptor-interacting serine-threonine kinase 2	8	90839109	AF064824	8767	8q21	Hs.103755	52	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity signal transducer activity protein binding ATP binding intracellular cytoplasm cytosol protein amino acid phosphorylation inflammatory response signal transduction transferase activity LIM domain binding positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 2 signaling pathway T cell proliferation positive regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JNK cascade CARD domain binding defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of ERK1 and ERK2 cascade	Neurotrophin signaling pathway
208936_x_at	0.468	6.008	4.088	9.437e-04	0.064	-0.537	LGALS8	lectin, galactoside-binding, soluble, 8	1	234748187, 234753361, 234753699	AF074000	3964	1q42-q43	Hs.4082 Hs.708114	29	sugar binding extracellular space cytoplasm
1552791_a_at	-1.566	9.065	-4.087	9.463e-04	0.064	-0.539	TRDN	triadin	6	-123579181	NM_006073	10345	6q22-q23	Hs.654601	19	receptor binding cytoplasm plasma membrane muscle contraction integral to membrane sarcoplasmic reticulum
209604_s_at	0.479	5.927	4.086	9.484e-04	0.064	-0.541	GATA3	GATA binding protein 3	10	8136672	BC003070	2625	10p15	Hs.524134	92	transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter defense response transcription factor binding zinc ion binding anatomical structure morphogenesis sequence-specific DNA binding response to estrogen stimulus metal ion binding
228099_at	0.584	6.394	4.085	9.502e-04	0.064	-0.543	ZNF550	zinc finger protein 550	19	-62750154	AI805301	162972	19q13.43	Hs.180257	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
242586_at	-0.800	6.623	-4.084	9.510e-04	0.064	-0.544	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	H07986	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
228070_at	-0.585	7.109	-4.084	9.524e-04	0.064	-0.545	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	14	-62911107	AI417519	5529	14q23.1	Hs.334868	20	protein phosphatase type 2A complex protein binding cytoplasm signal transduction protein phosphatase type 2A regulator activity intracellular membrane-bounded organelle	Wnt signaling pathway
220094_s_at	0.489	8.746	4.082	9.565e-04	0.064	-0.549	CCDC90A	coiled-coil domain containing 90A	6	-13898998	NM_022102	63933	6p24.3-p23	Hs.214043	3	mitochondrion membrane integral to membrane
226117_at	0.877	5.990	4.082	9.565e-04	0.064	-0.549	TIFA	TRAF-interacting protein with forkhead-associated domain	4	-113416230	AA195074	92610	4q25	Hs.310640	9	protein binding I-kappaB kinase/NF-kappaB cascade
236972_at	-1.204	10.165	-4.081	9.572e-04	0.064	-0.550	TRIM63	tripartite motif-containing 63	1	-26250384	AI351421	84676	1p34-p33	Hs.279709	20	ubiquitin-protein ligase activity signal transducer activity protein binding intracellular nucleus cytoplasm cytoplasm microtubule muscle contraction signal transduction zinc ion binding ligase activity modification-dependent protein catabolic process titin binding proteasomal ubiquitin-dependent protein catabolic process contractile fiber metal ion binding
218290_at	0.366	8.025	4.079	9.623e-04	0.064	-0.555	PLEKHJ1	pleckstrin homology domain containing, family J member 1	19	-2184154	NM_018049	55111	19p13.3	Hs.501353	5	protein binding
231966_at	-0.419	4.126	-4.075	9.686e-04	0.064	-0.561	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A	7	94374884	AB033048	55607	7q21.3	Hs.21816	12	actin binding protein binding cytoplasm cytoskeleton actin filament organization multicellular organismal development nervous system development synaptosome cell junction cell differentiation filopodium cortical actin cytoskeleton dendritic spine synapse
205583_s_at	-0.516	7.057	-4.075	9.691e-04	0.064	-0.562	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_024810	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
206314_at	0.479	4.170	4.074	9.704e-04	0.064	-0.563	ZNF167	zinc finger protein 167	3	44571716, 44571716	NM_018651	55888	3p22.3-p21.1	Hs.529512 Hs.696570	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222885_at	0.466	8.351	4.072	9.750e-04	0.064	-0.567	EMCN	endomucin	4	-101535522	AF205940	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
1556554_at	0.391	5.834	4.069	9.814e-04	0.065	-0.573	TRIM50	tripartite motif-containing 50	7	-72364470	AK057366	135892	7q11.23	Hs.647053	4	protein binding intracellular cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
208353_x_at	0.518	10.860	4.069	9.816e-04	0.065	-0.573	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_020480	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
225225_at	-0.380	10.855	-4.068	9.832e-04	0.065	-0.575	LOC729082	hypothetical protein LOC729082	15	39363492	BF791544	729082	15q15.1	Hs.380164	2
217908_s_at	-0.532	11.028	-4.068	9.834e-04	0.065	-0.575	DCAF6	DDB1 and CUL4 associated factor 6	1	166172531	NM_018442	55827	1q24.2	Hs.435741	10	nucleus ligand-dependent nuclear receptor transcription coactivator activity
229985_at	0.827	7.367	4.067	9.862e-04	0.065	-0.578	BTNL9	butyrophilin-like 9	5	180399830	AI912653	153579	5q35.3	Hs.546502	4	membrane integral to membrane
227271_at	0.588	6.348	4.066	9.869e-04	0.065	-0.578	FGF11	fibroblast growth factor 11	17	7283412	AU151265	2256	17p13.1	Hs.655193	7	signal transduction cell-cell signaling nervous system development growth factor activity	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
228438_at	0.882	3.703	4.065	9.893e-04	0.065	-0.581	LOC100132891	hypothetical protein LOC100132891	8		AI948599	100132891	8q13.3	Hs.137674
229052_at	-0.583	11.505	-4.065	9.899e-04	0.065	-0.581	ANKRD23	ankyrin repeat domain 23	2	-96867377	AI637712	200539	2q11.2	Hs.643430	8	nucleus
203208_s_at	-0.376	7.452	-4.061	9.976e-04	0.065	-0.588	MTFR1	mitochondrial fission regulator 1	8	66719441, 66719441, 66744661	NM_014637	9650	8q13.1	Hs.584788	8	mitochondrion plasma membrane
206014_at	-0.285	6.076	-4.059	1.002e-03	0.065	-0.592	ACTL6B	actin-like 6B	7	-100078661	NM_016188	51412	7q22	Hs.259831	12	structural constituent of cytoskeleton protein binding ATP binding nucleus SWI/SNF complex chromatin modification regulation of transcription
217957_at	0.549	8.066	4.058	1.004e-03	0.065	-0.594	C16orf80	chromosome 16 open reading frame 80	16	-56704997	NM_013242	29105	16q21	Hs.532755	3	multicellular organismal development
212998_x_at	1.038	5.689	4.057	1.006e-03	0.065	-0.596	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	AI583173	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
223369_at	0.431	8.079	4.057	1.006e-03	0.065	-0.596	METTL11A	methyltransferase like 11A	9	131428255	BC001396	28989	9q34.11	Hs.522433	5	protein binding methyltransferase activity transferase activity
203773_x_at	0.408	8.645	4.053	1.013e-03	0.065	-0.603	BLVRA	biliverdin reductase A	7	43764796	NM_000712	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
205202_at	-0.533	10.257	-4.052	1.016e-03	0.066	-0.605	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	6	150112523	NM_005389	5110	6q24-q25	Hs.279257	25	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding
1555522_s_at	-0.546	7.572	-4.050	1.020e-03	0.066	-0.609	MEMO1	mediator of cell motility 1	2	-31946398, -31946397	BC036262	51072	2p22-p21	Hs.444969	10	nucleus cytosol
218270_at	0.412	9.273	4.048	1.025e-03	0.066	-0.614	MRPL24	mitochondrial ribosomal protein L24	1	-154973717	NM_024540	79590	1q21-q22	Hs.418233	9	structural constituent of ribosome intracellular mitochondrion ribosome translation
211564_s_at	0.428	4.327	4.047	1.027e-03	0.066	-0.616	PDLIM4	PDZ and LIM domain 4	5	131621249	BC003096	8572	5q31.1	Hs.424312	20	protein binding zinc ion binding metal ion binding
1566860_at	-0.420	2.619	-4.045	1.031e-03	0.066	-0.619	LOC145663	hypothetical protein LOC145663	15		AK056979	145663	15q15.1	Hs.75335	1
212832_s_at	-0.312	7.957	-4.044	1.033e-03	0.066	-0.621	CKAP5	cytoskeleton associated protein 5	11	-46721659	AI143124	9793	11p11.2	Hs.201253	16	gamma-tubulin complex protein binding centrosome cell cycle mitosis microtubule cytoskeleton establishment or maintenance of microtubule cytoskeleton polarity RNA transport centrosome organization spindle pole body organization cell division
222589_at	-0.504	6.459	-4.043	1.036e-03	0.066	-0.623	NLK	nemo-like kinase	17	23393814	AI967933	51701	17q11.2	Hs.208759	24	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase activity ATP binding nucleus nucleolus cytoplasm transforming growth factor beta receptor signaling pathway protein kinase cascade transcription factor binding transferase activity peptidyl-threonine phosphorylation negative regulation of Wnt receptor signaling pathway ubiquitin protein ligase binding serine phosphorylation of STAT3 protein SH2 domain binding regulation of transcription protein amino acid autophosphorylation	MAPK signaling pathway Wnt signaling pathway Adherens junction
211729_x_at	0.398	8.716	4.041	1.038e-03	0.066	-0.626	BLVRA	biliverdin reductase A	7	43764796	BC005902	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
226982_at	-0.747	5.535	-4.041	1.040e-03	0.066	-0.627	ELL2	elongation factor, RNA polymerase II, 2	5	-95246557	AI745624	22936	5q15	Hs.192221 Hs.708710	6	RNA polymerase II transcription factor activity nucleus RNA elongation from RNA polymerase II promoter transcription elongation factor complex RNA polymerase II transcription elongation factor activity regulation of transcription
213592_at	0.696	6.462	4.040	1.041e-03	0.066	-0.628	APLNR	apelin receptor	11	-56757629	X89271	187	11q12	Hs.438311	29	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway	Neuroactive ligand-receptor interaction
205874_at	0.468	5.142	4.038	1.045e-03	0.066	-0.631	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A	15	39573413	NM_002220	3706	15q14-q21	Hs.2722	18	nucleotide binding calmodulin binding ATP binding inositol metabolic process signal transduction inositol trisphosphate 3-kinase activity kinase activity transferase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system
201121_s_at	0.521	7.839	4.038	1.046e-03	0.066	-0.633	PGRMC1	progesterone receptor membrane component 1	X	118254238	NM_006667	10857	Xq22-q24	Hs.90061	26	receptor activity steroid binding protein binding nucleus nucleolus endoplasmic reticulum microsome cell surface membrane integral to membrane heme binding
200608_s_at	-0.505	9.185	-4.038	1.046e-03	0.066	-0.633	RAD21	RAD21 homolog (S. pombe)	8	-117927354	NM_006265	5885	8q24	Hs.81848	33	nuclear chromosome protein binding nucleus double-strand break repair apoptosis response to DNA damage stimulus cell cycle chromosome segregation mitosis reciprocal meiotic recombination cell division	Cell cycle
219520_s_at	0.401	7.080	4.037	1.049e-03	0.066	-0.635	WWC3	WWC family member 3	X	9943794	NM_018458	55841	Xp22.32	Hs.527524	5
210716_s_at	-0.843	7.410	-4.036	1.049e-03	0.066	-0.635	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	M97501	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
205903_s_at	-0.455	4.868	-4.035	1.051e-03	0.066	-0.637	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1	-152946536, -152946536	NM_002249	3782	1q21.3	Hs.490765	40	ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity
207612_at	0.397	4.980	4.033	1.056e-03	0.066	-0.641	WNT8B	wingless-type MMTV integration site family, member 8B	10	102212801	NM_003393	7479	10q24	Hs.421281	8	signal transducer activity extracellular region proteinaceous extracellular matrix signal transduction Wnt receptor signaling pathway, calcium modulating pathway cell-cell signaling multicellular organismal development nervous system development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
202133_at	0.829	7.779	4.033	1.056e-03	0.066	-0.641	WWTR1	WW domain containing transcription regulator 1	3	-150720721	BF674349	25937	3q23-q24	Hs.719249	13	negative regulation of transcription from RNA polymerase II promoter osteoblast differentiation transcription coactivator activity transcription corepressor activity protein binding nucleus transcription factor complex nucleolus cytoplasm regulation of transcription, DNA-dependent transcription regulator activity glomerulus development protein homodimerization activity negative regulation of fat cell differentiation positive regulation of transcription from RNA polymerase II promoter cilium morphogenesis
224250_s_at	-0.599	7.930	-4.033	1.057e-03	0.066	-0.642	SECISBP2	SECIS binding protein 2	9	91123231	BC001189	79048	9q22.2	Hs.59804	20	RNA binding mRNA 3'-UTR binding nucleus translation
200733_s_at	-0.543	10.246	-4.032	1.059e-03	0.066	-0.644	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	U48296	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
208753_s_at	-0.574	8.160	-4.032	1.059e-03	0.066	-0.644	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	BC002387	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
1569986_x_at	-1.170	11.920	-4.031	1.061e-03	0.066	-0.646	TNNT3	troponin T type 3 (skeletal, fast)	11	1897374	BF789882	7140	11p15.5	Hs.73454	21	skeletal muscle contraction actin binding tropomyosin binding tropomyosin binding troponin complex regulation of striated muscle contraction troponin C binding calcium-dependent ATPase activity troponin I binding regulation of ATPase activity calcium-dependent protein binding
210156_s_at	-0.488	9.210	-4.029	1.066e-03	0.066	-0.650	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	6	150112523	D25547	5110	6q24-q25	Hs.279257	25	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding
207812_s_at	-0.565	7.617	-4.028	1.066e-03	0.066	-0.651	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	NM_015530	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
203895_at	0.767	5.013	4.028	1.067e-03	0.066	-0.651	PLCB4	phospholipase C, beta 4	20	9024931	AL535113	5332	20p12	Hs.472101	17	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding intracellular signaling cascade lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
202211_at	-0.483	6.940	-4.028	1.067e-03	0.066	-0.651	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	22	-41522475	BC005122	26286	22q13.2-q13.3	Hs.162877	15	cytoplasm Golgi apparatus cytosol intracellular protein transport ARF GTPase activator activity zinc ion binding protein transporter activity protein secretion membrane vesicle-mediated transport regulation of ARF GTPase activity metal ion binding	Endocytosis
217028_at	0.561	3.911	4.028	1.068e-03	0.066	-0.652	CXCR4	chemokine (C-X-C motif) receptor 4	2	-136588388, -136588388	AJ224869	7852	2q21	Hs.593413	604	activation of MAPK activity response to hypoxia actin binding G-protein coupled receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane apoptosis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration response to virus coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity initiation of viral infection cell leading edge myosin light chain binding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway Endocytosis Axon guidance Leukocyte transendothelial migration
209139_s_at	-0.524	9.622	-4.028	1.068e-03	0.066	-0.652	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	2	-179004387, -179004387, -179004387	AF083033	8575	2q31.2	Hs.570274	27	double-stranded RNA binding protein binding intracellular cytoplasm protein amino acid phosphorylation induction of apoptosis response to stress immune response enzyme activator activity negative regulation of cell proliferation response to virus RNA interference, production of siRNA gene silencing by RNA outer ear morphogenesis middle ear morphogenesis protein homodimerization activity perinuclear region of cytoplasm skeletal system morphogenesis
227674_at	0.522	5.421	4.026	1.071e-03	0.067	-0.655	ZNF585A	zinc finger protein 585A	19	-42332840, -42332840	AA910852	199704	19q13.12	Hs.390568 Hs.659236	3	nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226459_at	0.551	4.705	4.025	1.074e-03	0.067	-0.657	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	10	-98343058	AW575754	118788	10q24.1	Hs.310456	9	transmembrane receptor protein tyrosine kinase signaling protein activity protein binding cytoplasm plasma membrane	B cell receptor signaling pathway
235374_at	0.491	7.590	4.025	1.075e-03	0.067	-0.658	MDH1	malate dehydrogenase 1, NAD (soluble)	2	63669625	AW952547	4190	2p13.3	Hs.526521	18	malic enzyme activity binding soluble fraction cytoplasm cytosol cytosol glycolysis tricarboxylic acid cycle oxaloacetate metabolic process malate metabolic process oxidoreductase activity NAD metabolic process L-malate dehydrogenase activity L-malate dehydrogenase activity cellular carbohydrate metabolic process NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Pyruvate metabolism Glyoxylate and dicarboxylate metabolism Carbon fixation in photosynthetic organisms Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
240381_at	0.406	5.864	4.023	1.078e-03	0.067	-0.660	ZBED5	zinc finger, BED-type containing 5	11	-10830829	AA813103	58486	11p15.3	Hs.655066	5	DNA binding zinc ion binding metal ion binding
231987_at	0.440	6.030	4.020	1.084e-03	0.067	-0.666	LOC728264	hypothetical LOC728264	5	148766632	AW081196	728264	5q32	Hs.519666	1
1560238_at	0.910	4.247	4.020	1.086e-03	0.067	-0.667	LOC100127980	hypothetical protein LOC100127980	19		BM926839	100127980	19q13.12	Hs.595153	1
230040_at	0.854	3.671	4.019	1.087e-03	0.067	-0.669	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	16	-75873525	AI733120	170692	16q23	Hs.188746	9	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
217979_at	0.674	7.237	4.018	1.089e-03	0.067	-0.670	TSPAN13	tetraspanin 13	7	16759875	NM_014399	27075	7p21.1	Hs.364544	14	membrane fraction integral to plasma membrane membrane
212566_at	-0.444	10.545	-4.017	1.091e-03	0.067	-0.672	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AL523310	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
213530_at	-0.327	6.840	-4.014	1.098e-03	0.067	-0.678	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	AI040009	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
208857_s_at	-0.454	10.307	-4.013	1.100e-03	0.067	-0.680	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	6	150112523	M93008	5110	6q24-q25	Hs.279257	25	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding
240883_at	-0.679	3.356	-4.013	1.101e-03	0.067	-0.680	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	X	-54976314	AA702810	5207	Xp11.21	Hs.444304	11	nucleotide binding 6-phosphofructo-2-kinase activity 6-phosphofructo-2-kinase activity fructose-2,6-bisphosphate 2-phosphatase activity fructose-2,6-bisphosphate 2-phosphatase activity ATP binding cytosol fructose 2,6-bisphosphate metabolic process gluconeogenesis glycolysis protein kinase cascade metabolic process kinase activity transferase activity hydrolase activity identical protein binding 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex	Fructose and mannose metabolism
208617_s_at	-0.793	10.462	-4.012	1.102e-03	0.067	-0.681	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	AF208850	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
205489_at	2.200	7.246	4.010	1.107e-03	0.068	-0.686	CRYM	crystallin, mu	16	-21177342, -21177342	NM_001888	1428	16p13.11-p12.3	Hs.924	17	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity catalytic activity cytoplasm sensory perception of sound metabolic process thyroid hormone metabolic process protein homodimerization activity NADP or NADPH binding thyroid hormone binding thyroid hormone binding thyroid hormone transport
212470_at	-0.502	8.166	-4.010	1.107e-03	0.068	-0.686	SPAG9	sperm associated antigen 9	17	-46394534	AB011088	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
212588_at	0.684	4.854	4.009	1.110e-03	0.068	-0.688	PTPRC	protein tyrosine phosphatase, receptor type, C	1	196874759, 196874759	Y00062	5788	1q31-q32	Hs.654514	174	negative regulation of T cell mediated cytotoxicity negative regulation of cytokine-mediated signaling pathway immunoglobulin biosynthetic process transmembrane receptor protein tyrosine phosphatase activity protein binding plasma membrane integral to plasma membrane focal adhesion negative regulation of protein kinase activity negative regulation of protein kinase activity protein amino acid dephosphorylation cell surface receptor linked signal transduction hydrolase activity protein kinase binding T cell differentiation positive regulation of B cell proliferation regulation of S phase positive regulation of T cell proliferation positive regulation of protein kinase activity T cell receptor signaling pathway B cell receptor signaling pathway positive regulation of antigen receptor-mediated signaling pathway release of sequestered calcium ion into cytosol defense response to virus regulation of cell cycle	Cell adhesion molecules (CAMs) T cell receptor signaling pathway Fc gamma R-mediated phagocytosis Primary immunodeficiency
203909_at	-0.535	6.966	-4.009	1.110e-03	0.068	-0.688	SLC9A6	solute carrier family 9 (sodium/hydrogen exchanger), member 6	X	134895251	NM_006359	10479	Xq26.3	Hs.62185	11	mitochondrion endosome endoplasmic reticulum membrane microsome plasma membrane cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity integral to membrane sodium ion binding early endosome membrane recycling endosome membrane	Cardiac muscle contraction
212010_s_at	-0.500	10.577	-4.008	1.113e-03	0.068	-0.690	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	AK025647	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
202144_s_at	-0.612	9.944	-4.007	1.114e-03	0.068	-0.691	ADSL	adenylosuccinate lyase	22	39072449	NM_000026	158	22q13.1 22q13.2	Hs.75527	29	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity cytoplasm cytosol AMP biosynthetic process purine ribonucleotide biosynthetic process lyase activity protein tetramerization (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
229291_at	0.370	5.712	4.007	1.115e-03	0.068	-0.692	RBM15	RNA binding motif protein 15	1	110683467	AI743545	64783	1p13	Hs.435947 Hs.708172	13	nucleotide binding RNA binding protein binding nucleus negative regulation of transcription interspecies interaction between organisms
209029_at	-0.430	7.786	-4.005	1.119e-03	0.068	-0.695	COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	12	6703410, 6703440, 6703505, 6703709	AF193844	50813	12p13.31	Hs.530823	16	nucleus cytoplasm signalosome
227539_at	-1.008	5.704	-4.004	1.122e-03	0.068	-0.698	GNA13	guanine nucleotide binding protein (G protein), alpha 13	17	-60435870	AW298099	10672	17q24.3	Hs.515018	57	nucleotide binding patterning of blood vessels in utero embryonic development GTPase activity signal transducer activity protein binding GTP binding cell motion signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade Rho protein signal transduction regulation of cell shape membrane guanyl nucleotide binding cell differentiation platelet activation regulation of cell migration melanosome	Vascular smooth muscle contraction Long-term depression Regulation of actin cytoskeleton
228875_at	0.446	6.836	4.003	1.123e-03	0.068	-0.699	FAM162B	family with sequence similarity 162, member B	6	-117180053	AI540210	221303	6q22.1	Hs.126712	4	membrane integral to membrane
200684_s_at	-0.577	6.645	-4.002	1.125e-03	0.068	-0.700	UBE2L3	ubiquitin-conjugating enzyme E2L 3	22	20251956	AI819709	7332	22q11.21	Hs.108104 Hs.603229 Hs.715088	38	ubiquitin ligase complex nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity enzyme binding regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
217932_at	0.396	9.370	4.002	1.126e-03	0.068	-0.701	MRPS7	mitochondrial ribosomal protein S7	17	70769343	NM_015971	51081	17q25	Hs.71787	13	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation cytosolic small ribosomal subunit
201380_at	-0.465	5.827	-4.001	1.128e-03	0.068	-0.702	CRTAP	cartilage associated protein	3	33130453	NM_006371	10491	3p22.3	Hs.719160	10	extracellular region proteinaceous extracellular matrix
213188_s_at	-0.597	7.334	-4.000	1.130e-03	0.068	-0.704	MINA	MYC induced nuclear antigen	3	-99143350, -99143350	AI823896	84864	3q11.2	Hs.607776	15	nucleus nucleolus cytoplasm ribosome biogenesis
217725_x_at	-0.742	8.721	-4.000	1.130e-03	0.068	-0.705	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	NM_015640	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
203065_s_at	0.776	9.957	3.999	1.132e-03	0.068	-0.706	CAV1	caveolin 1, caveolae protein, 22kDa	7	115952074	NM_001753	857	7q31.1	Hs.74034	318	Golgi membrane Golgi membrane inactivation of MAPK activity vasculogenesis response to hypoxia negative regulation of endothelial cell proliferation intracellular endoplasmic reticulum Golgi apparatus lipid particle plasma membrane caveola triglyceride metabolic process calcium ion transport endocytosis regulation of smooth muscle contraction skeletal muscle tissue development protein localization positive regulation of calcium ion transport into cytosol cholesterol binding integral to membrane vesicle organization peptidase activator activity regulation of fatty acid metabolic process lipid storage regulation of blood coagulation cholesterol transport negative regulation of epithelial cell differentiation mammary gland development maintenance of protein location in cell response to progesterone stimulus protein complex scaffold nitric oxide homeostasis cholesterol homeostasis negative regulation of MAPKKK cascade response to estrogen stimulus interspecies interaction between organisms negative regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction negative regulation of vasodilation negative regulation of JAK-STAT cascade perinuclear region of cytoplasm positive regulation of metalloenzyme activity nitric-oxide synthase binding protein homooligomerization cytosolic calcium ion homeostasis response to calcium ion membrane depolarization regulation of peptidase activity mammary gland involution	Focal adhesion
218215_s_at	-0.453	6.227	-3.999	1.132e-03	0.068	-0.706	NR1H2	nuclear receptor subfamily 1, group H, member 2	19	55571496	NM_007121	7376	19q13.3-q13.3	Hs.432976	62	transcription factor activity steroid hormone receptor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding positive regulation of specific transcription from RNA polymerase II promoter negative regulation of foam cell differentiation positive regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux negative regulation of cholesterol storage negative regulation of transcription positive regulation of cellular protein metabolic process negative regulation of lipid transport sequence-specific DNA binding cellular lipid metabolic process positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of pinocytosis positive regulation of lipoprotein lipase activity
235176_at	0.399	4.461	3.998	1.136e-03	0.068	-0.709	ZFP82	zinc finger protein 82 homolog (mouse)	19	-41574700	AA927918	284406	19q13.12	Hs.558734	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
219396_s_at	0.328	6.138	3.995	1.141e-03	0.068	-0.714	NEIL1	nei endonuclease VIII-like 1 (E. coli)	15	73426383	NM_024608	79661	15q24.2	Hs.512732	35	damaged DNA binding DNA-(apurinic or apyrimidinic site) lyase activity nucleus cytoplasm base-excision repair nucleotide-excision repair response to DNA damage stimulus response to oxidative stress protein C-terminus binding metabolic process zinc ion binding lyase activity DNA N-glycosylase activity negative regulation of nuclease activity	Base excision repair
224752_at	-0.304	9.383	-3.995	1.143e-03	0.068	-0.715	PL-5283	PL-5283 protein	7	134997760	BG031051	647087	7q33	Hs.200022	3
218856_at	0.575	5.906	3.992	1.149e-03	0.069	-0.720	TNFRSF21	tumor necrosis factor receptor superfamily, member 21	6	-47307226	NM_016629	27242	6p21.1-p12.2	Hs.443577	15	receptor activity protein binding apoptosis signal transduction membrane integral to membrane	Cytokine-cytokine receptor interaction
225665_at	-0.492	11.862	-3.987	1.160e-03	0.069	-0.728	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AI129320	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
203389_at	0.340	5.823	3.987	1.160e-03	0.069	-0.729	KIF3C	kinesin family member 3C	2	-26002958	AF035621	3797	2p23	Hs.21611	9	nucleotide binding microtubule motor activity ATP binding kinesin complex microtubule microtubule-based movement
232119_at	-0.861	7.352	-3.987	1.161e-03	0.069	-0.729	SYNPO2	synaptopodin 2	4	120029443, 120029443	BF984227	171024	4q26	Hs.655519	14	actin binding protein binding nucleus cytoplasm
226426_at	-0.476	6.203	-3.986	1.163e-03	0.069	-0.731	ADNP	activity-dependent neuroprotector homeobox	20	-48940289	BG149849	23394	20q13.13	Hs.570355	10	chromatin binding transcription factor activity dolichyl-phosphate beta-D-mannosyltransferase activity protein binding extracellular space intracellular nucleus nucleolus regulation of transcription, DNA-dependent GPI anchor biosynthetic process zinc ion binding dolichol metabolic process negative regulation of neuron apoptosis sequence-specific DNA binding metal ion binding
214769_at	-0.569	8.644	-3.985	1.165e-03	0.069	-0.733	CLCN4	chloride channel 4	X	10084984	AF052117	1183	Xp22.3	Hs.495674	17	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding
201877_s_at	-0.481	8.601	-3.985	1.165e-03	0.069	-0.733	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma isoform	14	101297887, 101345892, 101345892	NM_002719	5527	14q32.31	Hs.368264 Hs.719337	37	protein phosphatase type 2A complex protein binding nucleus signal transduction protein phosphatase type 2A regulator activity proteasomal ubiquitin-dependent protein catabolic process	Wnt signaling pathway
200818_at	0.352	12.156	3.983	1.170e-03	0.069	-0.737	ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	21	-34197626	NM_001697	539	21q22.1-q22.2 21q22.11	Hs.409140	12	transporter activity mitochondrion mitochondrial proton-transporting ATP synthase complex mitochondrial proton-transporting ATP synthase complex plasma membrane ATP catabolic process ion transport drug binding proton transport ATPase activity mitochondrial ATP synthesis coupled proton transport proton-transporting ATP synthase complex, catalytic core F(1) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
225425_s_at	0.614	9.587	3.983	1.171e-03	0.069	-0.737	MRPL41	mitochondrial ribosomal protein L41	9	139566129	AV726260	64975	9q34.3	Hs.44017	10	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation apoptosis cell cycle
226063_at	0.404	5.453	3.982	1.172e-03	0.069	-0.738	VAV2	vav 2 guanine nucleotide exchange factor	9	-135616837	AA481141	7410	9q34.1	Hs.369921 Hs.689325	31	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular intracellular signaling cascade zinc ion binding diacylglycerol binding regulation of Rho protein signal transduction metal ion binding	Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton
226582_at	0.560	5.377	3.982	1.174e-03	0.069	-0.740	LOC400043	hypothetical LOC400043	12	52806121	AL520272	400043	12q13.13	Hs.19193	2
200835_s_at	-0.634	8.763	-3.981	1.175e-03	0.069	-0.741	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	AI553791	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
211656_x_at	0.521	6.352	3.978	1.183e-03	0.069	-0.747	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M32577	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
221688_s_at	-0.525	8.008	-3.976	1.187e-03	0.070	-0.751	IMP3	IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)	15	-73718490	AL136913	55272	15q24	Hs.513043	21	protein binding intracellular nucleus nucleolus rRNA processing rRNA binding ribonucleoprotein complex
239763_at	0.324	5.742	3.975	1.189e-03	0.070	-0.752	PRDM11	PR domain containing 11	11	45072139	AA157112	56981	11p11	Hs.178715	3
224583_at	0.628	4.477	3.974	1.191e-03	0.070	-0.753	COTL1	coactosin-like 1 (Dictyostelium)	16	-83156704	AL565621	23406	16q24.1	Hs.289092	18	actin binding cellular_component intracellular cytoplasm cytoskeleton biological_process enzyme binding defense response to fungus
206559_x_at	1.275	11.860	3.971	1.199e-03	0.070	-0.760	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	NM_001403	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
210024_s_at	-0.650	10.303	-3.969	1.204e-03	0.070	-0.764	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	2	181553356, 181553586	AB017644	10477	2q32.1	Hs.470804	20	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding nucleus cytoplasm ligase activity modification-dependent protein catabolic process regulation of growth post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
201705_at	-0.435	9.932	-3.969	1.205e-03	0.070	-0.764	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	16	72888181	NM_002811	5713	16q23-q24	Hs.440604	47	proteasome complex protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
206895_at	-0.861	9.946	-3.966	1.213e-03	0.071	-0.770	PPP1R3A	protein phosphatase 1, regulatory (inhibitor) subunit 3A	7	-113304117	NM_002711	5506	7q31.1	Hs.458309	24	carbohydrate metabolic process glycogen metabolic process membrane integral to membrane	Insulin signaling pathway
223519_at	-0.748	9.964	-3.965	1.213e-03	0.071	-0.770	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	AW069181	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
229553_at	-0.943	6.835	-3.962	1.221e-03	0.071	-0.777	PGM2L1	phosphoglucomutase 2-like 1	11	-73719008	AA736452	283209	11q13.4	Hs.26612	6	carbohydrate metabolic process glucose metabolic process transferase activity isomerase activity intramolecular transferase activity, phosphotransferases glucose-1,6-bisphosphate synthase activity	Starch and sucrose metabolism
218373_at	-0.515	9.125	-3.958	1.232e-03	0.071	-0.785	AKTIP	AKT interacting protein	16	-52082692	NM_022476	64400	16q12.2	Hs.380897	14	protein binding cytoplasm plasma membrane apoptosis endosome organization lysosome organization endosome to lysosome transport protein transport small conjugating protein ligase activity HOPS complex post-translational protein modification early endosome to late endosome transport regulation of protein metabolic process FHF complex
222989_s_at	-0.527	7.341	-3.958	1.232e-03	0.071	-0.785	UBQLN1	ubiquilin 1	9	-85464697	NM_013438	29979	9q21.2-q21.3 9q22	Hs.9589	46	nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm
201799_s_at	-0.537	6.906	-3.957	1.233e-03	0.071	-0.786	OSBP	oxysterol binding protein	11	-59098446	AI927993	5007	11q12-q13	Hs.597091	13	cytoplasm Golgi apparatus lipid transport oxysterol binding steroid metabolic process membrane
222985_at	-0.347	11.964	-3.957	1.233e-03	0.071	-0.786	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	7	-75794043	AB024334	7532	7q11.23	Hs.520974	56	protein kinase C binding insulin-like growth factor receptor binding cytoplasm negative regulation of protein kinase activity protein targeting protein kinase C inhibitor activity regulation of signal transduction protein domain specific binding regulation of neuron differentiation regulation of synaptic plasticity	Cell cycle Neurotrophin signaling pathway
225314_at	0.658	5.913	3.956	1.237e-03	0.071	-0.789	OCIAD2	OCIA domain containing 2	4	-48582161	BG291649	132299	4p11	Hs.95835	2	mitochondrion mitochondrial inner membrane endosome
200961_at	-0.507	8.180	-3.954	1.242e-03	0.071	-0.793	SEPHS2	selenophosphate synthetase 2	16	-30362452	NM_012248	22928	16p11.2	Hs.718460	7	nucleotide binding selenide, water dikinase activity ATP binding cellular_component selenium binding selenocysteine biosynthetic process transferase activity	Selenoamino acid metabolism Metabolic pathways
209140_x_at	0.682	10.715	3.952	1.248e-03	0.072	-0.796	HLA-B	major histocompatibility complex, class I, B	6	-31429627, -2770844, -2569111	L42024	3106	6p21.3	Hs.707171 Hs.77961	1101	antigen processing and presentation of peptide antigen via MHC class I protein binding membrane fraction plasma membrane integral to plasma membrane defense response immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
210140_at	0.385	5.489	3.949	1.256e-03	0.072	-0.803	CST7	cystatin F (leukocystatin)	20	24877865	AF031824	8530	20p11.21	Hs.143212	17	cysteine-type endopeptidase inhibitor activity extracellular region cytoplasm immune response
204311_at	0.379	5.735	3.948	1.256e-03	0.072	-0.803	ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	17	7494978	NM_001678	482	17p13.1	Hs.712542	22	sodium:potassium-exchanging ATPase activity protein binding ATP biosynthetic process ion transport potassium ion transport sodium ion transport membrane integral to membrane potassium ion binding sodium ion binding	Cardiac muscle contraction
204838_s_at	-0.448	6.456	-3.945	1.264e-03	0.072	-0.809	MLH3	mutL homolog 3 (E. coli)	14	-74550219	NM_014381	27030	14q24.3	Hs.436650	28	satellite DNA binding protein binding ATP binding nucleus mismatch repair response to DNA damage stimulus reciprocal meiotic recombination mismatched DNA binding	Mismatch repair
229534_at	0.507	4.631	3.944	1.268e-03	0.072	-0.811	ACOT4	acyl-CoA thioesterase 4	14	73128162	AA046424	122970	14q24.3	Hs.49433	10	very-long-chain fatty acid metabolic process carboxylesterase activity peroxisome succinyl-CoA metabolic process lipid metabolic process acyl-CoA metabolic process palmitoyl-CoA hydrolase activity hydrolase activity thiolester hydrolase activity saturated monocarboxylic acid metabolic process unsaturated monocarboxylic acid metabolic process butanoic acid metabolic process dicarboxylic acid metabolic process	Biosynthesis of unsaturated fatty acids
209071_s_at	0.523	10.586	3.944	1.268e-03	0.072	-0.811	RGS5	regulator of G-protein signaling 5	1	-161378720	AF159570	8490	1q23.1	Hs.24950	26	signal transducer activity GTPase activator activity regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction
226592_at	0.385	5.056	3.943	1.269e-03	0.072	-0.812	ZNF618	zinc finger protein 618	9	115678382	AA031404	114991	9q32	Hs.349208	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity
231836_at	0.605	5.249	3.943	1.269e-03	0.072	-0.812	HKR1	GLI-Kruppel family member HKR1	19	42517419	BC004513	284459	19q13.12	Hs.657027	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding metal ion binding
212774_at	-0.865	10.201	-3.943	1.270e-03	0.072	-0.813	ZNF238	zinc finger protein 238	1	242281183, 242283204	AJ223321	10472	1q44-qter	Hs.69997	11	negative regulation of transcription from RNA polymerase II promoter nuclear chromosome transcription factor activity protein binding intracellular nucleus transport zinc ion binding regulation of transcription metal ion binding
227705_at	1.221	5.007	3.942	1.272e-03	0.072	-0.814	TCEAL7	transcription elongation factor A (SII)-like 7	X	102471820	BF591534	56849	Xq22.1	Hs.21861	7	nucleus regulation of transcription
218545_at	-0.546	7.762	-3.942	1.272e-03	0.072	-0.815	CCDC91	coiled-coil domain containing 91	12	28301399	NM_018318	55297	12p11.22	Hs.653125	8	Golgi apparatus protein transport membrane
219436_s_at	0.551	6.908	3.941	1.275e-03	0.072	-0.817	EMCN	endomucin	4	-101535522	NM_016242	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
203705_s_at	-0.816	7.321	-3.941	1.275e-03	0.072	-0.817	FZD7	frizzled homolog 7 (Drosophila)	2	202607554	AI333651	8324	2q33	Hs.173859	23	non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway multicellular organismal development integral to membrane Wnt receptor signaling pathway Wnt receptor activity	Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma
200768_s_at	-0.426	8.543	-3.940	1.277e-03	0.072	-0.819	MAT2A	methionine adenosyltransferase II, alpha	2	85619798	BC001686	4144	2p11.2	Hs.516157	18	nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
223589_at	0.407	5.059	3.940	1.278e-03	0.072	-0.819	ZNF416	zinc finger protein 416	19	-62774745	BC000130	55659	19q13.4	Hs.247711	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212870_at	-0.840	9.163	-3.939	1.280e-03	0.072	-0.821	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	AI628605	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
224327_s_at	0.572	6.076	3.939	1.282e-03	0.072	-0.822	DGAT2	diacylglycerol O-acyltransferase homolog 2 (mouse)	11	75157425	AB048286	84649	11q13.5	Hs.334305	16	2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity membrane fraction endoplasmic reticulum glycerol metabolic process acyltransferase activity lipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process	Glycerolipid metabolism Retinol metabolism Metabolic pathways
217983_s_at	0.501	6.444	3.937	1.286e-03	0.072	-0.825	RNASET2	ribonuclease T2	6	-167262993	NM_003730	8635	6q27	Hs.529989	11	RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity
219106_s_at	-0.331	12.637	-3.937	1.287e-03	0.072	-0.825	KBTBD10	kelch repeat and BTB (POZ) domain containing 10	2	170074457	NM_006063	10324	2q31.1	Hs.50550	8	ruffle protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion striated muscle contraction modification-dependent protein catabolic process pseudopodium
233385_x_at	0.328	6.406	3.937	1.287e-03	0.072	-0.826	RAB4B	RAB4B, member RAS oncogene family	19	45976010	AK024845	53916	19q13.2	Hs.631539	5	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
212116_at	0.389	5.761	3.936	1.288e-03	0.072	-0.826	TRIM27	tripartite motif-containing 27	6	-28978757, -330309, -128126	NM_006510	5987	6p22	Hs.440382	27	negative regulation of transcription from RNA polymerase II promoter DNA binding transmembrane receptor protein tyrosine kinase activity protein binding intracellular membrane fraction nucleus nucleoplasm cytoplasm integral to plasma membrane spermatogenesis zinc ion binding cell proliferation nuclear membrane regulation of transcription negative regulation of gene expression, epigenetic metal ion binding protein trimerization
209838_at	-0.873	7.200	-3.935	1.290e-03	0.072	-0.828	COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	15	-47204762	AA496247	9318	15q21.2	Hs.369614	37	signal transducer activity protein binding protein binding nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter signal transduction signalosome
204778_x_at	0.435	6.252	3.934	1.293e-03	0.072	-0.830	HOXB7	homeobox B7	17	-44039593	AW102783	3217	17q21.3	Hs.436181	39	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation myeloid cell differentiation sequence-specific DNA binding embryonic skeletal system morphogenesis
243980_at	0.318	4.330	3.934	1.293e-03	0.072	-0.830	ZNF594	zinc finger protein 594	17	-5023554	AW978739	84622	17p13	Hs.658402	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225717_at	-0.941	6.412	-3.934	1.295e-03	0.072	-0.831	KIAA1715	KIAA1715	2	-176498655	AI814587	80856	2q31	Hs.209561	7	protein binding multicellular organismal development membrane integral to membrane limb development
201388_at	-0.412	7.184	-3.934	1.295e-03	0.072	-0.831	PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	17	35390585	NM_002809	5709	17q21.1	Hs.12970	34	proteasome complex protein binding cytosol enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
205117_at	0.525	6.008	3.933	1.297e-03	0.072	-0.833	FGF1	fibroblast growth factor 1 (acidic)	5	-141951926, -141951926, -141951926, -141951926, -141951926	X59065	2246	5q31	Hs.483635	114	angiogenesis induction of an organ protein binding extracellular region proteinaceous extracellular matrix extracellular space signal transduction multicellular organismal development growth factor activity heparin binding cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis cell differentiation lung development positive regulation of epithelial cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
224630_at	-0.356	7.942	-3.933	1.297e-03	0.072	-0.833	ERLEC1	endoplasmic reticulum lectin 1	2	53867571	AK001913	27248	2p16.2	Hs.438336 Hs.713845	10	protein binding endoplasmic reticulum endoplasmic reticulum lumen
1552430_at	0.296	2.228	3.932	1.299e-03	0.072	-0.834	WDR17	WD repeat domain 17	4	177224125	NM_170710	116966	4q34	Hs.532056	3
244740_at	1.240	6.242	3.932	1.299e-03	0.072	-0.834	MGC9913	hypothetical protein MGC9913	19		BE855713	386759	19q13.43	Hs.23133	1
205427_at	0.353	5.729	3.931	1.302e-03	0.072	-0.836	ZNF354A	zinc finger protein 354A	5	-178071127	NM_005649	6940	5q35.3	Hs.484324	8	DNA binding RNA polymerase II transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter sensory perception of sound zinc ion binding metal ion binding
218651_s_at	1.268	6.598	3.931	1.303e-03	0.072	-0.837	LARP6	La ribonucleoprotein domain family, member 6	15	-68930821, -68910942	NM_018357	55323	15q23	Hs.416755	5	RNA binding nucleus cytoplasm RNA processing ribonucleoprotein complex
223652_at	0.855	6.104	3.930	1.304e-03	0.072	-0.838	AS3MT	arsenic (+3 oxidation state) methyltransferase	10	104619199	AF226730	57412	10q24.32	Hs.34492	24	soluble fraction cytoplasm cytosol metabolic process methyltransferase activity toxin metabolic process transferase activity arsonoacetate metabolic process arsenite methyltransferase activity methylarsonite methyltransferase activity response to arsenic
234694_at	0.376	5.237	3.925	1.319e-03	0.073	-0.848	CNTROB	centrobin, centrosomal BRCA2 interacting protein	17	7776197	AF141344	116840	17p13.1	Hs.348012	8	cytokinesis centriole cell cycle centriole replication protein domain specific binding centrosome separation
91682_at	0.374	5.283	3.924	1.320e-03	0.073	-0.849	EXOSC4	exosome component 4	8	145205509	AI571298	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
226925_at	0.694	5.058	3.921	1.329e-03	0.073	-0.855	ACPL2	acid phosphatase-like 2	3	142433371	AW069729	92370	3q23	Hs.657887	2	acid phosphatase activity extracellular region hydrolase activity
212149_at	-0.552	9.238	-3.921	1.330e-03	0.073	-0.856	EFR3A	EFR3 homolog A (S. cerevisiae)	8	132985540	AW470003	23167	8q24.22	Hs.204564	4	binding plasma membrane
224859_at	0.332	5.886	3.921	1.330e-03	0.073	-0.856	CD276	CD276 molecule	15	71763674	AL360136	80381	15q23-q24	Hs.77873	23	receptor binding cell proliferation external side of plasma membrane membrane integral to membrane positive regulation of bone mineralization positive regulation of T cell proliferation T cell activation negative regulation of T cell proliferation negative regulation of interferon-gamma biosynthetic process positive regulation of interferon-gamma biosynthetic process negative regulation of interleukin-2 biosynthetic process positive regulation of osteoblast differentiation negative regulation of inflammatory response regulation of immune response	Cell adhesion molecules (CAMs)
200798_x_at	-0.868	6.800	-3.919	1.335e-03	0.073	-0.860	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	1	-148813658	NM_021960	4170	1q21	Hs.719112	154	cell fate determination protein binding nucleus nucleoplasm cytoplasm mitochondrion mitochondrial outer membrane anti-apoptosis multicellular organismal development protein channel activity membrane integral to membrane cellular homeostasis cell differentiation response to cytokine stimulus regulation of apoptosis protein heterodimerization activity
207040_s_at	-0.512	10.356	-3.918	1.336e-03	0.073	-0.860	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	22	-39550546	NM_003932	6767	22q13.2	Hs.712713	29	binding cytoplasm protein folding protein binding, bridging
235291_s_at	0.461	4.037	3.918	1.337e-03	0.073	-0.861	FLJ32255	hypothetical protein LOC643977	5		BE875232	643977	5p12	Hs.535791	1
206209_s_at	0.437	6.436	3.916	1.341e-03	0.073	-0.864	CA4	carbonic anhydrase IV	17	55582083	NM_000717	762	17q23	Hs.89485	30	carbonate dehydratase activity membrane fraction plasma membrane one-carbon metabolic process visual perception zinc ion binding lyase activity anchored to membrane metal ion binding response to stimulus	Nitrogen metabolism
220044_x_at	-0.397	8.877	-3.916	1.342e-03	0.073	-0.864	LUC7L3	LUC7-like 3 (S. cerevisiae)	17	46151975	NM_016424	51747	17q21.33	Hs.130293	15	DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck
202814_s_at	-0.759	7.357	-3.916	1.343e-03	0.073	-0.865	HEXIM1	hexamethylene bis-acetamide inducible 1	17	40580466	AW193511	10614	17q21.31	Hs.586945 Hs.634944 Hs.716487	28	negative regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm heart development specific transcriptional repressor activity snRNA binding regulation of transcription negative regulation of cyclin-dependent protein kinase activity
230393_at	0.412	5.909	3.915	1.346e-03	0.073	-0.867	CUL5	cullin 5	11	107384617	BF448201	8065	11q22-q23	Hs.440320 Hs.701122	38	G1/S transition of mitotic cell cycle receptor activity calcium channel activity protein binding cytosol ubiquitin-dependent protein catabolic process cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding interspecies interaction between organisms	Ubiquitin mediated proteolysis
203752_s_at	-0.586	8.942	-3.915	1.347e-03	0.073	-0.868	JUND	jun D proto-oncogene	19	-18251562	NM_005354	3727	19p13.2	Hs.2780	67	chromatin osteoblast development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding positive regulation of osteoblast differentiation protein dimerization activity	MAPK signaling pathway
1405_i_at	0.580	3.772	3.914	1.349e-03	0.073	-0.869	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	M21121	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
214106_s_at	0.517	5.044	3.912	1.355e-03	0.073	-0.873	GMDS	GDP-mannose 4,6-dehydratase	6	-1569039	AI762113	2762	6p25	Hs.144496 Hs.660919	11	binding intracellular cytoplasm carbohydrate metabolic process leukocyte adhesion GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process cellular metabolic process coenzyme binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
209070_s_at	0.734	10.150	3.911	1.355e-03	0.073	-0.873	RGS5	regulator of G-protein signaling 5	1	-161378720	AI183997	8490	1q23.1	Hs.24950	26	signal transducer activity GTPase activator activity regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction
212061_at	-0.554	7.260	-3.911	1.358e-03	0.073	-0.875	SR140	U2-associated SR140 protein	3	144203061	AB002330	23350	3q23	Hs.596572	4	nucleotide binding RNA binding RNA processing
218013_x_at	-0.748	6.579	-3.909	1.361e-03	0.073	-0.877	DCTN4	dynactin 4 (p62)	5	-150068502, -150068502	NM_016221	51164	5q31-q32	Hs.675564	7	nucleus cytoplasm centrosome cytoskeleton protein N-terminus binding	Huntington's disease
217356_s_at	-0.944	10.442	-3.908	1.364e-03	0.073	-0.880	PGK1	phosphoglycerate kinase 1	X	77246321	S81916	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
222448_s_at	-0.611	7.474	-3.908	1.366e-03	0.073	-0.881	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	1	47572055	AF112216	51727	1p32	Hs.714325	16	nucleotide binding cytidylate kinase activity uridine kinase activity ATP binding nucleus cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine ribonucleotide biosynthetic process transferase activity phosphotransferase activity, phosphate group as acceptor	Pyrimidine metabolism Metabolic pathways
218733_at	-0.548	6.394	-3.907	1.367e-03	0.073	-0.882	MSL2	male-specific lethal 2 homolog (Drosophila)	3	-137350449, -137350449	NM_018133	55167	3q22.3	Hs.18631	8	protein binding zinc ion binding metal ion binding
228109_at	0.380	6.056	3.907	1.368e-03	0.073	-0.882	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2	5	80292313	AI912976	5924	5q13	Hs.162129	11	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular cytoplasm endoplasmic reticulum plasma membrane regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway
223046_at	-0.565	10.533	-3.905	1.373e-03	0.074	-0.886	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	AL117352	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
209412_at	-0.508	6.010	-3.905	1.374e-03	0.074	-0.886	TRAPPC10	trafficking protein particle complex 10	21	44256633	U61500	7109	21q22.3	Hs.126221	12	Golgi apparatus sodium ion transport sodium ion transmembrane transporter activity integral to membrane vesicle-mediated transport
225344_at	0.532	6.390	3.904	1.375e-03	0.074	-0.887	NCOA7	nuclear receptor coactivator 7	6	126153693	AL035689	135112	6q22.32	Hs.171426	18	protein binding intracellular nucleus cell wall macromolecule catabolic process regulation of transcription
200998_s_at	0.408	6.621	3.904	1.375e-03	0.074	-0.887	CKAP4	cytoskeleton-associated protein 4	12	-105155789	AW029619	10970	12q23.3	Hs.714862 Hs.74368	22	membrane fraction endoplasmic reticulum membrane integral to membrane
241866_at	0.856	4.232	3.904	1.376e-03	0.074	-0.888	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	AW975728	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
218507_at	0.418	5.653	3.900	1.387e-03	0.074	-0.895	C7orf68	chromosome 7 open reading frame 68	7	127883119	NM_013332	29923	7q32.1	Hs.710088	9	molecular_function cellular_component response to stress membrane integral to membrane
209487_at	0.449	6.152	3.900	1.388e-03	0.074	-0.896	RBPMS	RNA binding protein with multiple splicing	8	30361485, 30361485	D84109	11030	8p12-p11	Hs.334587	8	nucleotide binding RNA binding protein binding RNA processing
207057_at	1.398	6.095	3.898	1.392e-03	0.074	-0.898	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)	12	58369392	NM_004731	9194	12q13	Hs.439643	8	pyruvate secondary active transmembrane transporter activity membrane fraction plasma membrane integral to plasma membrane transport pyruvate transport symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport
206254_at	-1.093	7.646	-3.898	1.392e-03	0.074	-0.899	EGF	epidermal growth factor (beta-urogastrone)	4	111053488	NM_001963	1950	4q25	Hs.419815	289	activation of MAPKK activity angiogenesis epidermal growth factor receptor binding calcium ion binding protein binding extracellular region extracellular space plasma membrane DNA replication signal transduction epidermal growth factor receptor signaling pathway growth factor activity integral to membrane positive regulation of granule cell precursor proliferation transmembrane receptor protein tyrosine kinase activator activity platelet alpha granule lumen positive regulation of phosphorylation positive regulation of MAP kinase activity positive regulation of epidermal growth factor receptor activity positive regulation of mitosis branching morphogenesis of a tube regulation of protein secretion regulation of peptidyl-tyrosine phosphorylation negative regulation of secretion	MAPK signaling pathway ErbB signaling pathway Cytokine-cytokine receptor interaction Endocytosis Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Non-small cell lung cancer
202747_s_at	0.543	8.325	3.898	1.394e-03	0.074	-0.900	ITM2A	integral membrane protein 2A	X	-78502536	NM_004867	9452	Xq13.3-Xq21.2	Hs.17109 Hs.694944	14	cytoplasm plasma membrane integral to membrane
238996_x_at	-0.906	11.637	-3.898	1.394e-03	0.074	-0.900	ALDOA	aldolase A, fructose-bisphosphate	16	29971991, 29983100, 29983473, 29984544	AI921586	226	16p11.2	Hs.513490	55	actin binding fructose-bisphosphate aldolase activity glycolysis ATP biosynthetic process striated muscle contraction actin filament organization metabolic process regulation of cell shape actin cytoskeleton tubulin binding lyase activity fructose 1,6-bisphosphate metabolic process I band identical protein binding muscle maintenance fructose binding extracellular vesicular exosome	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
202222_s_at	-0.407	11.468	-3.898	1.395e-03	0.074	-0.900	DES	desmin	2	219991342	NM_001927	1674	2q35	Hs.594952	57	structural constituent of cytoskeleton protein binding intracellular insoluble fraction cytoplasm cytoskeleton muscle contraction cytoskeleton organization regulation of heart contraction Z disc sarcolemma contractile fiber type III intermediate filament synapse	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
209154_at	0.901	8.433	3.897	1.395e-03	0.074	-0.900	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	17	-3512937	AF234997	30851	17p13	Hs.12956	14	nucleus cytoplasm Rho protein signal transduction beta-catenin binding negative regulation of cell proliferation negative regulation of Wnt receptor signaling pathway transcription regulator activity
228410_at	0.427	5.115	3.896	1.399e-03	0.074	-0.903	GAB3	GRB2-associated binding protein 3	X	-153556720	AA495984	139716	Xq28	Hs.496982	4
219126_at	-0.679	7.551	-3.896	1.399e-03	0.074	-0.903	PHF10	PHD finger protein 10	6	-169845925	NM_018288	55274	6q27	Hs.435933	14	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
220939_s_at	-0.532	9.023	-3.895	1.401e-03	0.074	-0.905	DPP8	dipeptidyl-peptidase 8	15	-63525050, -63525050	NM_017743	54878	15q22	Hs.591106	16	aminopeptidase activity nucleus cytoplasm proteolysis immune response peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity membrane
211678_s_at	-0.561	8.537	-3.892	1.410e-03	0.074	-0.911	RNF114	ring finger protein 114	20	47986320	AF090934	55905	20q13.13	Hs.144949	9	protein binding intracellular multicellular organismal development spermatogenesis zinc ion binding cell differentiation metal ion binding
218323_at	-0.481	8.036	-3.889	1.419e-03	0.075	-0.916	RHOT1	ras homolog gene family, member T1	17	27493585, 27493585	NM_018307	55288	17q11.2	Hs.655325	14	nucleotide binding molecular_function calcium ion binding protein binding GTP binding intracellular mitochondrion mitochondrial outer membrane apoptosis small GTPase mediated signal transduction membrane integral to membrane hydrolase activity cellular homeostasis integral to mitochondrial outer membrane mitochondrion transport along microtubule
213477_x_at	1.059	11.975	3.888	1.422e-03	0.075	-0.918	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	AL515273	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
226124_at	0.470	5.319	3.888	1.423e-03	0.075	-0.919	ZFP90	zinc finger protein 90 homolog (mouse)	16	67131161	AA747309	146198	16q22.1	Hs.461074 Hs.709017	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226474_at	0.529	5.782	3.887	1.425e-03	0.075	-0.920	NLRC5	NLR family, CARD domain containing 5	16	55580910	AA005023	84166	16q13	Hs.528836	3	nucleotide binding protein binding ATP binding cytoplasm
217816_s_at	-0.428	9.041	-3.886	1.427e-03	0.075	-0.922	PCNP	PEST proteolytic signal containing nuclear protein	3	102775731	NM_020357	57092	3q12.3	Hs.545311 Hs.654949	6	protein binding nucleus cell cycle protein ubiquitination proteasomal ubiquitin-dependent protein catabolic process
230249_at	-1.180	5.937	-3.886	1.429e-03	0.075	-0.923	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	8	136538897	AI650382	10656	8q24.2	Hs.444558	20	RNA binding protein binding nucleus nucleolus cytoplasm spermatogenesis SH3 domain binding regulation of transcription
225999_at	-0.603	5.149	-3.886	1.429e-03	0.075	-0.923	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AI743612	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
206116_s_at	-0.880	13.052	-3.884	1.432e-03	0.075	-0.925	TPM1	tropomyosin 1 (alpha)	15	61121890, 61121890, 61127688	NM_000366	7168	15q22.1	Hs.133892	76	stress fiber positive regulation of heart rate by epinephrine actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction cytoskeleton organization regulation of heart contraction structural constituent of muscle sarcomere muscle filament sliding negative regulation of cell migration ruffle organization bleb ruffle membrane positive regulation of ATPase activity cellular response to reactive oxygen species wound healing sarcomere organization positive regulation of cell adhesion positive regulation of stress fiber formation ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
211799_x_at	0.499	8.293	3.882	1.439e-03	0.075	-0.929	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	U62824	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
200895_s_at	-0.552	8.114	-3.880	1.446e-03	0.075	-0.934	FKBP4	FK506 binding protein 4, 59kDa	12	2774368	NM_002014	2288	12p13.33	Hs.524183 Hs.713721	47	peptidyl-prolyl cis-trans isomerase activity ATP binding GTP binding FK506 binding intracellular nucleus nucleolus cytoplasm protein folding steroid hormone receptor complex assembly copper ion transport embryo implantation isomerase activity protein binding, bridging heat shock protein binding protein complex localization glucocorticoid receptor binding male sex differentiation phosphoprotein binding
1553172_at	-0.566	5.849	-3.879	1.447e-03	0.075	-0.935	ZNF777	zinc finger protein 777	7	-148759386	NM_015694	27153	7q36.1	Hs.38512	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225324_at	-0.716	7.581	-3.876	1.458e-03	0.076	-0.942	CRLS1	cardiolipin synthase 1	20	5934738, 5935897	AL035461	54675	20p13-p12.3	Hs.224764	14	mitochondrion mitochondrial inner membrane phospholipid biosynthetic process membrane integral to membrane transferase activity phosphotransferase activity, for other substituted phosphate groups	Glycerophospholipid metabolism Metabolic pathways
212845_at	-0.523	10.495	-3.875	1.459e-03	0.076	-0.942	SAMD4A	sterile alpha motif domain containing 4A	14	54104386, 54291255	AB028976	23034	14q22.2	Hs.98259	4	cytoplasm synaptosome translation repressor activity dendrite positive regulation of translation
1554628_at	0.626	3.887	3.875	1.461e-03	0.076	-0.943	ZNF57	zinc finger protein 57	19	2851895	BC028974	126295	19p13.3	Hs.591378	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212203_x_at	0.603	9.583	3.874	1.463e-03	0.076	-0.944	IFITM3	interferon induced transmembrane protein 3 (1-8U)	11	-309672	BF338947	10410	11p15.5	Hs.374650	13	plasma membrane immune response response to biotic stimulus integral to membrane
225339_at	-0.542	8.195	-3.874	1.464e-03	0.076	-0.945	SPAG9	sperm associated antigen 9	17	-46394534	BG290577	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
209982_s_at	0.353	4.303	3.874	1.464e-03	0.076	-0.945	NRXN2	neurexin 2	11	-64130221, -64130221	AA608820	9379	11q13	Hs.372938	16	calcium ion binding protein binding cell adhesion membrane integral to membrane	Cell adhesion molecules (CAMs)
207436_x_at	-0.421	7.983	-3.872	1.469e-03	0.076	-0.948	KIAA0894	KIAA0894 protein	10		NM_014896	22833	10q23.33		1
223041_at	-0.514	7.409	-3.871	1.471e-03	0.076	-0.950	CD99L2	CD99 molecule-like 2	X	-149685466	AL136580	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
224710_at	0.507	5.939	3.870	1.477e-03	0.076	-0.953	RAB34	RAB34, member RAS oncogene family	17	-24065425, -24065425, -24065425	AF322067	83871	17q11.2	Hs.301853	16	nucleotide binding ruffle GTPase activity GTP binding cytoplasm early endosome Golgi apparatus endocytosis small GTPase mediated signal transduction protein transport guanyl nucleotide binding
226831_at	-0.586	8.781	-3.869	1.478e-03	0.076	-0.954	SLC25A46	solute carrier family 25, member 46	5	110102652	AA928542	91137	5q22.1	Hs.75639	5	binding cellular_component mitochondrion mitochondrial inner membrane transport biological_process membrane integral to membrane
205584_at	-0.368	6.114	-3.867	1.485e-03	0.076	-0.958	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_024810	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
232684_at	0.758	4.991	3.866	1.488e-03	0.076	-0.961	LOC253264	hypothetical protein LOC253264	10		AK023445	253264	10q22.2	Hs.662111	1
225398_at	-0.664	9.382	-3.866	1.489e-03	0.076	-0.961	RPUSD4	RNA pseudouridylate synthase domain containing 4	11	-125577199	AL580514	84881	11q24.2	Hs.150458	5	pseudouridine synthesis RNA binding pseudouridine synthase activity
236937_at	-0.595	5.404	-3.865	1.491e-03	0.076	-0.962	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)	3	186012624	BF108423	23355	3q27.2	Hs.269263	6	protein binding zinc ion binding metal ion binding
204655_at	0.557	4.472	3.865	1.492e-03	0.076	-0.963	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	NM_002985	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
208264_s_at	-0.837	8.048	-3.861	1.503e-03	0.077	-0.970	EIF3J	eukaryotic translation initiation factor 3, subunit J	15	42616557	NM_003758	8669	15q21.1	Hs.404056	19	translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation
226879_at	0.318	6.393	3.858	1.514e-03	0.077	-0.976	HVCN1	hydrogen voltage-gated channel 1	12	-109570873, -109570873	AW406569	84329	12q24.11	Hs.211511 Hs.334637	11	voltage-gated ion channel activity ion transport response to pH response to zinc ion response to zinc ion proton transport membrane integral to membrane voltage-gated proton channel activity voltage-gated proton channel activity
229762_at	0.507	5.304	3.857	1.515e-03	0.077	-0.977	C7orf38	chromosome 7 open reading frame 38	7	-98981858	AI740938	221786	7q22.1	Hs.596587	6	membrane integral to membrane
235128_at	-0.680	10.270	-3.856	1.520e-03	0.077	-0.980	SYNPO	synaptopodin	5	150000412, 150000412	AI569782	11346	5q33.1	Hs.435228 Hs.591256 Hs.714870	20	actin binding cytoplasm plasma membrane tight junction postsynaptic density actin cytoskeleton cell junction cell projection dendritic spine perikaryon synapse postsynaptic membrane
228027_at	0.490	7.503	3.855	1.521e-03	0.077	-0.981	GPRASP2	G protein-coupled receptor associated sorting protein 2	X	101853995	BF732712	114928	Xq22.1	Hs.603154	11	protein binding cytoplasm
212886_at	-0.472	9.167	-3.854	1.525e-03	0.077	-0.983	CCDC69	coiled-coil domain containing 69	5	-150540805	AL080169	26112	5q33.1	Hs.655336	3
218598_at	-0.499	6.015	-3.853	1.527e-03	0.078	-0.985	RINT1	RAD50 interactor 1	7	104959767	NM_021930	60561	7q22.3	Hs.531388	12	protein binding cytoplasm endoplasmic reticulum cell cycle protein transport membrane vesicle-mediated transport G2/M transition DNA damage checkpoint
243481_at	0.350	4.148	3.852	1.531e-03	0.078	-0.987	RHOJ	ras homolog gene family, member J	14	62740897	AA181207	57381	14q23.2	Hs.656339	8	nucleotide binding GTPase activity protein binding GTP binding cellular_component intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape actin cytoskeleton organization
205726_at	-0.787	6.840	-3.852	1.533e-03	0.078	-0.988	DIAPH2	diaphanous homolog 2 (Drosophila)	X	95826317, 95826317	NM_006729	1730	Xq21.33	Hs.226483 Hs.716101	14	cytokinesis actin binding receptor binding cytoplasm early endosome Golgi apparatus cytosol multicellular organismal development cellular component organization Rho GTPase binding actin cytoskeleton organization cell differentiation oogenesis	Regulation of actin cytoskeleton
205836_s_at	-0.715	5.254	-3.851	1.535e-03	0.078	-0.989	YTHDC2	YTH domain containing 2	5	112877308	NM_022828	64848	5q22.2	Hs.231942	6	nucleotide binding nucleic acid binding helicase activity ATP binding hydrolase activity
208709_s_at	-0.415	9.962	-3.850	1.538e-03	0.078	-0.991	NRD1	nardilysin (N-arginine dibasic convertase)	1	-52027453	U64898	4898	1p32.2-p32.1	Hs.584782	18	metalloendopeptidase activity protein binding cytosol proteolysis neuromuscular junction development peptidase activity zinc ion binding cell proliferation cell surface cell migration metal ion binding epidermal growth factor binding positive regulation of membrane protein ectodomain proteolysis regulation of endopeptidase activity
1558080_s_at	0.430	3.350	3.846	1.552e-03	0.078	-0.999	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	13	95127402	BG913589	5611	13q32.1	Hs.59214	19	protein kinase inhibitor activity binding cytoplasm endoplasmic reticulum response to unfolded protein response to virus heat shock protein binding
235503_at	-0.666	10.949	-3.844	1.557e-03	0.078	-1.003	ASB5	ankyrin repeat and SOCS box-containing 5	4	-177371821	BF589787	140458	4q34.2	Hs.591712	4	intracellular signaling cascade modification-dependent protein catabolic process
1569949_at	0.915	8.496	3.844	1.558e-03	0.078	-1.003	GRK5	G protein-coupled receptor kinase 5	10	120957186	BC018116	2869	10q24-qter	Hs.524625	38	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity protein kinase C binding protein binding ATP binding phospholipid binding soluble fraction cytoplasm plasma membrane protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger tachykinin receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway transferase activity	Chemokine signaling pathway Endocytosis
242002_at	0.524	4.931	3.843	1.558e-03	0.078	-1.003	NKAIN2	Na+/K+ transporting ATPase interacting 2	6	124166767	N62814	154215	6q21	Hs.656604	6	plasma membrane integral to membrane
226394_at	-0.475	7.152	-3.842	1.562e-03	0.078	-1.005	MARCH5	membrane-associated ring finger (C3HC4) 5	10	94040899	BE966193	54708	10q23.32-q23.33	Hs.573490	8	mitochondrion mitochondrial outer membrane zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
239004_at	0.263	5.936	3.842	1.564e-03	0.078	-1.007	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	AI041019	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
212694_s_at	0.553	8.281	3.841	1.566e-03	0.078	-1.008	PCCB	propionyl Coenzyme A carboxylase, beta polypeptide	3	137451856	NM_000532	5096	3q21-q22	Hs.63788	26	nucleotide binding propionyl-CoA carboxylase activity ATP binding mitochondrion mitochondrial matrix ligase activity	Valine, leucine and isoleucine degradation Propanoate metabolism Metabolic pathways
215718_s_at	-0.384	3.970	-3.841	1.567e-03	0.078	-1.009	PHF3	PHD finger protein 3	6	64414389	AI949220	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
212103_at	-0.475	7.476	-3.841	1.567e-03	0.078	-1.009	KPNA6	karyopherin alpha 6 (importin alpha 7)	1	32346230	BG403834	23633	1p35.1-p34.3	Hs.470588 Hs.711019	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
225578_at	-0.742	7.671	-3.839	1.571e-03	0.078	-1.011	C13orf37	chromosome 13 open reading frame 37	13	-72180495	AI885466	440145	13q21.33-q22.1	Hs.28465	1
230218_at	0.601	5.009	3.839	1.573e-03	0.078	-1.012	HIC1	hypermethylated in cancer 1	17	1905142, 1906353	BF476403	3090	17p13.3	Hs.695682 Hs.72956	25	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding metal ion binding
219825_at	0.860	4.693	3.839	1.574e-03	0.078	-1.013	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1	2	-72209874	NM_019885	56603	2p13.2	Hs.91546	11	cell fate determination retinoic acid binding endoplasmic reticulum microsome male meiosis spermatogenesis retinoic acid 4-hydroxylase activity electron carrier activity proximal/distal pattern formation membrane heme binding embryonic limb morphogenesis retinoic acid catabolic process metal ion binding negative regulation of retinoic acid receptor signaling pathway oxidation reduction	Retinol metabolism
230995_at	-0.618	5.806	-3.838	1.576e-03	0.078	-1.014	CMBL	carboxymethylenebutenolidase homolog (Pseudomonas)	5	-10330706	AW294145	134147	5p15.2	Hs.192586	4	protein binding hydrolase activity	gamma-Hexachlorocyclohexane degradation Fluorobenzoate degradation 1,4-Dichlorobenzene degradation Metabolic pathways
219341_at	0.435	5.041	3.838	1.578e-03	0.078	-1.015	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	8	1699276	NM_018941	2055	8p23	Hs.127675	15	age-dependent response to oxidative stress endoplasmic reticulum ER-Golgi intermediate compartment phospholipid metabolic process lipid transport mitochondrial membrane organization lysosome organization nervous system development adult walking behavior cholesterol metabolic process associative learning regulation of cell size lipid biosynthetic process membrane integral to membrane spinal cord motor neuron differentiation social behavior negative regulation of apoptosis cellular protein catabolic process cellular macromolecule catabolic process photoreceptor cell maintenance negative regulation of proteolysis ceramide biosynthetic process musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate uptake during transmission of nerve impulse retina development in camera-type eye neurofilament cytoskeleton organization
221502_at	-0.724	10.595	-3.837	1.580e-03	0.078	-1.016	KPNA3	karyopherin alpha 3 (importin alpha 4)	13	-49171444	AL120704	3839	13q14.3	Hs.527919	61	protein binding nucleus nuclear pore cytoplasm protein complex assembly NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity
214177_s_at	-0.759	8.347	-3.835	1.585e-03	0.079	-1.019	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	1	-153183179	AI935162	57326	1q21.3	Hs.505806	8	transcription corepressor activity protein binding nucleus cytoplasm cytosol cytoskeleton microtubule multicellular organismal development negative regulation of transcription cell differentiation
213462_at	0.499	5.750	3.834	1.588e-03	0.079	-1.021	NPAS2	neuronal PAS domain protein 2	2	100803044	AW000928	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
212601_at	-0.404	7.404	-3.833	1.592e-03	0.079	-1.024	ZZEF1	zinc finger, ZZ-type with EF-hand domain 1	17	-3854487	AB007859	23140	17p13.2	Hs.277624	4	protein binding anaphase-promoting complex zinc ion binding regulation of mitotic metaphase/anaphase transition metal ion binding
200721_s_at	-0.387	7.848	-3.831	1.600e-03	0.079	-1.028	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	10	-104228976	NM_005736	10121	10q24.32	Hs.153961	26	nucleotide binding protein binding ATP binding cytoplasm centrosome cytoskeleton dynactin complex vesicle-mediated transport
215046_at	-0.768	4.470	-3.828	1.609e-03	0.079	-1.033	C2orf67	chromosome 2 open reading frame 67	2	-210593679	AL133053	151050	2q34	Hs.282260 Hs.591638	4
1554717_a_at	-0.589	4.173	-3.828	1.610e-03	0.079	-1.034	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	BC008390	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
205040_at	0.576	4.148	3.826	1.616e-03	0.079	-1.037	ORM1	orosomucoid 1	9	116125123	NM_000607	5004	9q31-q32	Hs.522356	55	regulation of immune system process protein binding extracellular region extracellular space acute-phase response inflammatory response
235953_at	0.660	4.455	3.825	1.618e-03	0.079	-1.038	ZNF610	zinc finger protein 610	19	57531309, 57540493	AA776810	162963	19q13.41	Hs.357663	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218168_s_at	-0.524	11.345	-3.823	1.624e-03	0.080	-1.042	CABC1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	1	225194560	NM_020247	56997	1q42.13	Hs.118241	10	nucleotide binding ATP binding mitochondrion cell death kinase activity transferase activity
217362_x_at	0.457	6.863	3.823	1.624e-03	0.080	-1.042	HLA-DRB6	major histocompatibility complex, class II, DR beta 6 (pseudogene)	6	-32628467, -3714099	AF005487	3128	6p21.3	Hs.696211	7
226490_at	0.490	3.681	3.819	1.639e-03	0.080	-1.050	NHSL1	NHS-like 1	6	-138784873, -138784873	AA503387	57224	6q23.3	Hs.652741	3
228905_at	-0.627	7.869	-3.819	1.639e-03	0.080	-1.050	PCM1	pericentriolar material 1	8	17824645	BE672700	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
201687_s_at	-0.495	7.295	-3.819	1.639e-03	0.080	-1.050	API5	apoptosis inhibitor 5	11	43290080	NM_006595	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
238994_at	-0.494	5.652	-3.817	1.644e-03	0.080	-1.053	OTUD7B	OTU domain containing 7B	1	-148178855	AW022496	56957	1q21.2	Hs.98322	11	DNA binding ubiquitin thiolesterase activity protein binding nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding protein deubiquitination modification-dependent protein catabolic process negative regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
235944_at	1.069	5.508	3.817	1.647e-03	0.080	-1.055	HMCN1	hemicentin 1	1	183970305	BF446673	83872	1q25.3-q31.1	Hs.58877	14	calcium ion binding extracellular region basement membrane visual perception bioluminescence protein-chromophore linkage response to stimulus
235032_at	-0.554	8.020	-3.816	1.649e-03	0.080	-1.056	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	5	34965454	BG112118	134218	5p13.2	Hs.131887	5	nucleic acid binding intracellular zinc ion binding heat shock protein binding metal ion binding
212184_s_at	-0.691	7.951	-3.814	1.655e-03	0.080	-1.059	MAP3K7IP2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	6	149680755	AL117407	23118	6q25.1-q25.3	Hs.269775	39	protein binding intracellular cytoplasm cytosol cytosol zinc ion binding membrane positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway Toll-like receptor signaling pathway
202112_at	0.596	9.404	3.814	1.656e-03	0.080	-1.060	VWF	von Willebrand factor	12	-5928300	NM_000552	7450	12p13.3	Hs.440848	371	liver development placenta development glycoprotein binding protease binding integrin binding collagen binding extracellular region extracellular region extracellular region proteinaceous extracellular matrix endoplasmic reticulum plasma membrane response to wounding external side of plasma membrane immunoglobulin binding platelet activation platelet activation platelet alpha granule cell-substrate adhesion Weibel-Palade body protein homodimerization activity protein N-terminus binding chaperone binding protein homooligomerization	Focal adhesion ECM-receptor interaction Complement and coagulation cascades
229958_at	0.633	6.777	3.814	1.657e-03	0.080	-1.060	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	8	1699276	W93695	2055	8p23	Hs.127675	15	age-dependent response to oxidative stress endoplasmic reticulum ER-Golgi intermediate compartment phospholipid metabolic process lipid transport mitochondrial membrane organization lysosome organization nervous system development adult walking behavior cholesterol metabolic process associative learning regulation of cell size lipid biosynthetic process membrane integral to membrane spinal cord motor neuron differentiation social behavior negative regulation of apoptosis cellular protein catabolic process cellular macromolecule catabolic process photoreceptor cell maintenance negative regulation of proteolysis ceramide biosynthetic process musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate uptake during transmission of nerve impulse retina development in camera-type eye neurofilament cytoskeleton organization
209281_s_at	-0.582	6.140	-3.811	1.667e-03	0.080	-1.066	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	12	-88505956	M95541	490	12q21.3	Hs.506276	38	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
227025_at	-0.369	6.105	-3.811	1.668e-03	0.080	-1.066	PPHLN1	periphilin 1	12	41006213, 41006213, 41006213, 41006213	BG284497	51535	12q12	Hs.444157	13	nucleus cytoplasm keratinization
220709_at	0.843	5.270	3.811	1.668e-03	0.080	-1.066	ZNF556	zinc finger protein 556	19	2818332	NM_024967	80032	19p13.3	Hs.287433	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
243618_s_at	0.449	8.093	3.810	1.669e-03	0.080	-1.067	ZNF827	zinc finger protein 827	4	-146901337	BF678830	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
204806_x_at	0.498	8.027	3.809	1.673e-03	0.080	-1.069	HLA-F	major histocompatibility complex, class I, F	6	29799095, 29799095, 1143812, 1143812, 945922, 945922	NM_018950	3134	6p21.3	Hs.519972	68	antigen processing and presentation of peptide antigen via MHC class I immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
212169_at	0.508	8.166	3.809	1.674e-03	0.080	-1.070	FKBP9	FK506 binding protein 9, 63 kDa	7	32963529	AL050187	11328	7p11.1	Hs.103934	7	peptidyl-prolyl cis-trans isomerase activity calcium ion binding endoplasmic reticulum protein folding isomerase activity
213056_at	0.495	3.725	3.809	1.674e-03	0.080	-1.070	FRMD4B	FERM domain containing 4B	3	-69301835	AU145019	23150	3p14.1	Hs.709671	5	binding cytoplasm cytoskeleton
221950_at	0.538	3.887	3.808	1.675e-03	0.080	-1.070	EMX2	empty spiracles homeobox 2	10	119291945	AI478455	2018	10q26.1	Hs.202095	17	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation dentate gyrus development cell proliferation in forebrain forebrain cell migration neuron differentiation response to drug sequence-specific DNA binding
226398_s_at	0.383	7.559	3.808	1.676e-03	0.080	-1.071	C10orf4	chromosome 10 open reading frame 4	10	-95418318	AI804930	118924	10q23.33	Hs.658192	7	protein binding nucleus
209748_at	-0.515	6.626	-3.808	1.677e-03	0.080	-1.072	SPAST	spastin	2	32142183	AB029006	6683	2p24-p21	Hs.468091	90	nucleotide binding microtubule bundle formation ATP binding ATP binding nucleus nucleus cytoplasm endosome endoplasmic reticulum centrosome spindle microtubule ER to Golgi vesicle-mediated transport cell cycle cytokinesis, completion of separation multicellular organismal development nervous system development microtubule binding microtubule binding cell death microtubule-severing ATPase activity membrane integral to membrane hydrolase activity nucleoside-triphosphatase activity cell differentiation midbody protein hexamerization ATPase activity, uncoupled alpha-tubulin binding perinuclear region of cytoplasm beta-tubulin binding microtubule severing protein homooligomerization cell division
234980_at	-1.116	6.810	-3.808	1.678e-03	0.080	-1.072	TMEM56	transmembrane protein 56	1	95355481	AI004375	148534	1p21.3	Hs.483512	3	molecular_function cellular_component biological_process membrane integral to membrane
201023_at	-0.563	9.598	-3.807	1.682e-03	0.080	-1.074	TAF7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	5	-140678240	NM_005642	6879	5q31	Hs.438838	38	spermine transport transcription factor activity transcription coactivator activity nucleus transcription factor TFIID complex nucleolus cytoplasm Golgi apparatus transcription initiation from RNA polymerase II promoter negative regulation of protein kinase activity positive transcription elongation factor complex b negative regulation of specific transcription from RNA polymerase II promoter promoter binding general RNA polymerase II transcription factor activity specific transcriptional repressor activity transcription initiation factor activity estrogen receptor signaling pathway transcription factor TFTC complex histone acetyltransferase binding negative regulation of histone acetylation vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding	Basal transcription factors
225674_at	-0.653	8.510	-3.802	1.698e-03	0.081	-1.083	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	AW873330	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
229492_at	0.344	4.126	3.801	1.701e-03	0.081	-1.085	VANGL1	vang-like 1 (van gogh, Drosophila)	1	115986096	R85437	81839	1p11-p13.1	Hs.515130	12	protein binding multicellular organismal development membrane integral to membrane	Wnt signaling pathway
204950_at	0.530	6.268	3.801	1.701e-03	0.081	-1.085	CARD8	caspase recruitment domain family, member 8	19	-53403154	NM_014959	22900	19q13.33	Hs.446146 Hs.655940	23	protein binding intracellular nucleus cytoplasm caspase activator activity NACHT domain binding protein homodimerization activity regulation of apoptosis negative regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of caspase activity positive regulation of interleukin-1 beta secretion
207738_s_at	-0.492	8.149	-3.800	1.704e-03	0.081	-1.087	NCKAP1	NCK-associated protein 1	2	-183497849	NM_013436	10787	2q32	Hs.603732	20	protein binding plasma membrane apoptosis central nervous system development integral to membrane cell projection	Regulation of actin cytoskeleton
221577_x_at	2.082	4.455	3.799	1.708e-03	0.081	-1.089	GDF15	growth differentiation factor 15	19	18357967	AF003934	9518	19p13.11	Hs.616962	77	cytokine activity extracellular region extracellular space signal transduction transforming growth factor beta receptor signaling pathway cell-cell signaling growth factor activity
229109_s_at	0.291	5.161	3.799	1.709e-03	0.081	-1.089	BLVRA	biliverdin reductase A	7	43764796	N21095	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
1559413_at	-0.515	4.591	-3.798	1.711e-03	0.081	-1.090	TCP11L2	t-complex 11 (mouse)-like 2	12	105220710	AF306858	255394	12q23.3	Hs.696047	1
219848_s_at	0.504	5.699	3.798	1.712e-03	0.081	-1.091	ZNF432	zinc finger protein 432	19	-57228488	NM_014650	9668	19q13.41	Hs.655934	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
217984_at	0.460	6.335	3.797	1.714e-03	0.081	-1.092	RNASET2	ribonuclease T2	6	-167262993	NM_003730	8635	6q27	Hs.529989	11	RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity
217707_x_at	-0.588	8.916	-3.797	1.716e-03	0.081	-1.093	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	AI535683	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
205750_at	0.569	7.099	3.797	1.717e-03	0.081	-1.093	BPHL	biphenyl hydrolase-like (serine hydrolase)	6	3063924	NM_004332	670	6p25	Hs.10136	12	mitochondrion cellular amino acid and derivative metabolic process response to toxin hydrolase activity
1559871_s_at	0.608	4.114	3.796	1.718e-03	0.081	-1.094	LOC100129129	hypothetical protein LOC100129129	8		BC038546	100129129	8p23.1	Hs.662094
200878_at	0.456	10.038	3.796	1.719e-03	0.081	-1.095	EPAS1	endothelial PAS domain protein 1	2	46378066	AF052094	2034	2p21-p16	Hs.468410	101	angiogenesis response to hypoxia embryonic placenta development blood vessel remodeling regulation of heart rate RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus transcription factor complex transcription factor complex cytoplasm regulation of transcription, DNA-dependent response to oxidative stress mitochondrion organization signal transduction multicellular organismal development visual perception transcription factor binding hemopoiesis cell differentiation erythrocyte differentiation lung development histone acetyltransferase binding norepinephrine metabolic process surfactant homeostasis sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity cell maturation	Pathways in cancer Renal cell carcinoma
219807_x_at	0.299	6.340	3.796	1.720e-03	0.081	-1.095	RAB4B	RAB4B, member RAS oncogene family	19	45976010	NM_016154	53916	19q13.2	Hs.631539	5	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
203846_at	-0.520	7.396	-3.793	1.729e-03	0.081	-1.100	TRIM32	tripartite motif-containing 32	9	118489401	BC003154	22954	9q33.1	Hs.591910	18	transcription coactivator activity intracellular nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process ubiquitin binding protein self-association fat cell differentiation metal ion binding	Ubiquitin mediated proteolysis
221295_at	0.327	4.973	3.790	1.740e-03	0.082	-1.106	CIDEA	cell death-inducing DFFA-like effector a	18	12244317, 12244627	NM_001279	1149	18 18p11.21	Hs.249129	15	temperature homeostasis protein binding intracellular nucleus cytoplasm mitochondrion mitochondrial envelope lipid particle DNA fragmentation involved in apoptosis lipid metabolic process cell death DNA damage response, signal transduction resulting in induction of apoptosis positive regulation of sequestering of triglyceride lipid storage negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of tumor necrosis factor production protein homodimerization activity negative regulation of apoptosis negative regulation of cytokine secretion negative regulation of lipid catabolic process
37950_at	-0.503	7.856	-3.790	1.741e-03	0.082	-1.106	PREP	prolyl endopeptidase	6	-105832198	X74496	5550	6q22	Hs.436564	26	serine-type endopeptidase activity cytoplasm proteolysis peptidase activity
224709_s_at	-0.419	6.971	-3.788	1.746e-03	0.082	-1.109	CDC42SE2	CDC42 small effector 2	5	130627600	AF131831	56990	5q23.3-q31.1	Hs.508829 Hs.713870	8	structural molecule activity protein binding cytoplasm cytoskeleton plasma membrane phagocytosis regulation of cell shape regulation of signal transduction
226284_at	-0.676	5.152	-3.788	1.746e-03	0.082	-1.109	ZBTB2	zinc finger and BTB domain containing 2	6	-151726942	BF111616	57621	6q25.1	Hs.520073	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
238327_at	0.565	3.656	3.787	1.751e-03	0.082	-1.112	ODF3B	outer dense fiber of sperm tails 3B	22	-49315703	AI962367	440836	22q13.33	Hs.531314	6
203826_s_at	0.388	6.287	3.787	1.752e-03	0.082	-1.112	PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	11	-67015815	NM_004910	9600	11q13	Hs.372295	17	calcium ion binding intracellular membrane fraction cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process brain development phototransduction phosphatidylinositol transporter activity monolayer-surrounded lipid storage body protein transport membrane
212388_at	-0.797	7.751	-3.785	1.757e-03	0.082	-1.115	USP24	ubiquitin specific peptidase 24	1	-55304619	AB028980	23358	1p32.3	Hs.477009	13	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
230708_at	0.347	4.821	3.785	1.758e-03	0.082	-1.116	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	AA206141	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
1565759_at	-0.387	5.615	-3.783	1.764e-03	0.082	-1.119	RPL13	ribosomal protein L13	16	88154590, 88154631	BG396520	6137	16q24.3 17p11.2	Hs.410817	17	RNA binding structural constituent of ribosome protein binding intracellular cytosol translational elongation cytosolic ribosome	Ribosome
218764_at	0.569	6.988	3.782	1.767e-03	0.082	-1.120	PRKCH	protein kinase C, eta	14	60858267	NM_024064	5583	14q22-q23	Hs.333907	65	nucleotide binding protein kinase C activity ATP binding protein amino acid phosphorylation intracellular signaling cascade zinc ion binding transferase activity enzyme binding diacylglycerol binding metal ion binding	Vascular smooth muscle contraction Tight junction
215847_at	0.672	3.540	3.782	1.770e-03	0.082	-1.122	HERC2P3	hect domain and RLD 2 pseudogene 3	15		BC000975	283755	15q11.1	Hs.531509 Hs.655732	5	ubiquitin-protein ligase activity protein ubiquitination metal ion binding
225131_at	-0.637	7.856	-3.782	1.770e-03	0.082	-1.122	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	H60265	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
209244_s_at	-0.312	8.255	-3.780	1.775e-03	0.083	-1.124	KIF1C	kinesin family member 1C	17	4841999	BE885926	10749	17p13.2	Hs.435120	8	nucleotide binding microtubule motor activity ATP binding endoplasmic reticulum Golgi apparatus microtubule retrograde vesicle-mediated transport, Golgi to ER microtubule-based movement
222417_s_at	-0.595	8.144	-3.778	1.783e-03	0.083	-1.129	SNX5	sorting nexin 5	20	-17870243, -17870243	AF121855	27131	20p11	Hs.316890	14	protein binding cell communication protein transport phosphoinositide binding
212549_at	-0.580	7.854	-3.778	1.784e-03	0.083	-1.129	STAT5B	signal transducer and activator of transcription 5B	17	-37604720	BE645861	6777	17q11.2	Hs.719121	128	allantoin metabolic process luteinization natural killer cell differentiation transcription factor activity signal transducer activity calcium ion binding protein binding nucleus cytoplasm citrate metabolic process 2-oxoglutarate metabolic process succinate metabolic process oxaloacetate metabolic process isoleucine metabolic process valine metabolic process creatine metabolic process fatty acid metabolic process signal transduction female pregnancy lactation positive regulation of cell proliferation regulation of steroid metabolic process cytokine-mediated signaling pathway taurine metabolic process lipid storage regulation of cell adhesion regulation of epithelial cell differentiation response to estradiol stimulus cellular response to hormone stimulus T cell differentiation in the thymus glucocorticoid receptor binding positive regulation of multicellular organism growth positive regulation of activated T cell proliferation progesterone metabolic process T cell homeostasis negative regulation of apoptosis positive regulation of interleukin-2 biosynthetic process positive regulation of B cell differentiation positive regulation of gamma-delta T cell differentiation negative regulation of erythrocyte differentiation positive regulation of survival gene product expression positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter creatinine metabolic process development of secondary female sexual characteristics development of secondary male sexual characteristics Peyer's patch development positive regulation of inflammatory response JAK-STAT cascade involved in growth hormone signaling pathway	ErbB signaling pathway Chemokine signaling pathway Jak-STAT signaling pathway Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia
222108_at	0.512	4.170	3.775	1.793e-03	0.083	-1.134	AMIGO2	adhesion molecule with Ig-like domain 2	12	-45756649, -45755757	AC004010	347902	12q13.11	Hs.121520	7	protein binding nucleus plasma membrane cell adhesion homophilic cell adhesion heterophilic cell adhesion integral to membrane negative regulation of programmed cell death
208997_s_at	0.790	7.151	3.775	1.794e-03	0.083	-1.134	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	11	-73363363	U82819	7351	11q13	Hs.80658	153	response to superoxide binding mitochondrion mitochondrial inner membrane transport mitochondrial transport proton transport membrane integral to membrane
228962_at	-0.604	7.188	-3.774	1.796e-03	0.083	-1.136	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	BF507941	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
212071_s_at	0.430	9.860	3.773	1.801e-03	0.083	-1.138	SPTBN1	spectrin, beta, non-erythrocytic 1	2	54536957, 54639034	BE968833	6711	2p21	Hs.503178 Hs.705692	46	actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping
216210_x_at	0.340	7.426	3.773	1.802e-03	0.083	-1.138	TRIOBP	TRIO and F-actin binding protein	22	36422940, 36472186, 36472186	AA046650	11078	22q13.1	Hs.533030	20	actin binding protein binding nucleus cytoplasm actin cytoskeleton GTP-Rho binding actin modification myosin II binding barbed-end actin filament capping
222700_at	-0.693	7.622	-3.772	1.804e-03	0.083	-1.139	ATL2	atlastin GTPase 2	2	-38375534	AV700003	64225	2p22.2-p22.1	Hs.594950	8	nucleotide binding GTPase activity GTP binding membrane integral to membrane
220617_s_at	-0.389	8.309	-3.771	1.807e-03	0.083	-1.141	ZNF532	zinc finger protein 532	18	54681040	NM_018181	55205	18q21.32	Hs.529023 Hs.607676	4	DNA binding intracellular nucleus nucleolus Golgi apparatus zinc ion binding regulation of transcription metal ion binding
209015_s_at	-0.469	10.020	-3.771	1.809e-03	0.083	-1.142	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	7	156822470, 156822471	BC002446	10049	7q36.3	Hs.593923 Hs.719116	25	ATPase activator activity DNA binding nucleus cytoplasm protein folding response to unfolded protein transcription repressor activity heat shock protein binding negative regulation of caspase activity intermediate filament organization negative regulation of transcription, DNA-dependent perinuclear region of cytoplasm chaperone binding
203566_s_at	-0.568	11.889	-3.770	1.811e-03	0.083	-1.143	AGL	amylo-1, 6-glucosidase, 4-alpha-glucanotransferase	1	100088227, 100088632, 100089118, 100099353	NM_000645	178	1p21	Hs.904	26	4-alpha-glucanotransferase activity amylo-alpha-1,6-glucosidase activity amylo-alpha-1,6-glucosidase activity cytosol carbohydrate metabolic process glycogen biosynthetic process metabolic process transferase activity, transferring glycosyl groups hydrolase activity, acting on glycosyl bonds isoamylase complex cation binding	Starch and sucrose metabolism Metabolic pathways
1552731_at	-1.597	8.049	-3.769	1.815e-03	0.083	-1.145	ABRA	actin-binding Rho activating protein	8	-107840886	NM_139166	137735	8q23.1	Hs.374668	12	protein import into nucleus, translocation transcription coactivator activity actin binding cytoplasm plasma membrane protein transport actin cytoskeleton sarcomere positive regulation of Rho protein signal transduction positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription factor activity intracellular protein transmembrane transport
226317_at	-0.621	6.772	-3.768	1.819e-03	0.083	-1.147	PPP4R2	protein phosphatase 4, regulatory subunit 2	3	73128808	AI983837	151987	3p13	Hs.431092	7	protein binding centrosome mRNA processing protein modification process RNA splicing
1553613_s_at	0.609	4.803	3.768	1.820e-03	0.083	-1.148	FOXC1	forkhead box C1	6	1555679	NM_001453	2296	6p25	Hs.348883	51	skeletal system development ossification ovarian follicle development blood vessel development ureteric bud development in utero embryonic development kidney development lymph vessel development blood vessel remodeling heart morphogenesis RNA polymerase II transcription factor activity, enhancer binding nucleus nucleus nuclear heterochromatin anti-apoptosis Notch signaling pathway brain development transcription factor binding DNA bending activity germ cell migration neural crest cell development transcription activator activity collagen fibril organization glycosaminoglycan metabolic process lacrimal gland development embryonic heart tube development odontogenesis of dentine-containing tooth camera-type eye development sequence-specific DNA binding negative regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter regulation of organ growth vascular endothelial growth factor receptor signaling pathway paraxial mesoderm formation mesenchymal cell differentiation artery morphogenesis regulation of blood vessel size ventricular cardiac muscle morphogenesis cardiac muscle cell proliferation
224711_at	-0.460	7.839	-3.766	1.828e-03	0.084	-1.152	YY1	YY1 transcription factor	14	99774854	AI670903	7528	14q	Hs.388927	97	transcription factor activity transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus transcription factor complex plasma membrane regulation of transcription from RNA polymerase II promoter zinc ion binding anterior/posterior pattern formation nuclear matrix PcG protein complex metal ion binding camera-type eye morphogenesis
210284_s_at	-0.552	6.650	-3.766	1.829e-03	0.084	-1.153	MAP3K7IP2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	6	149680755	AF241230	23118	6q25.1-q25.3	Hs.269775	39	protein binding intracellular cytoplasm cytosol cytosol zinc ion binding membrane positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	MAPK signaling pathway Toll-like receptor signaling pathway
227889_at	0.345	4.849	3.764	1.834e-03	0.084	-1.155	LPCAT2	lysophosphatidylcholine acyltransferase 2	16	54100413	AI765437	54947	16q12.2	Hs.460857	4	calcium ion binding endoplasmic reticulum Golgi apparatus Golgi stack platelet activating factor biosynthetic process metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane membrane organization transferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-alkylglycerophosphocholine O-acetyltransferase activity
220419_s_at	-0.631	9.493	-3.764	1.837e-03	0.084	-1.156	USP25	ubiquitin specific peptidase 25	21	16024366	NM_013396	29761	21q11.2	Hs.473370	11	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
1556051_a_at	0.608	4.579	3.763	1.839e-03	0.084	-1.157	BICD1	bicaudal D homolog 1 (Drosophila)	12	32151451	CA777994	636	12p11.2-p11.1	Hs.505202	17	structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis
218694_at	-0.606	8.432	-3.762	1.841e-03	0.084	-1.158	ARMCX1	armadillo repeat containing, X-linked 1	X	100692169	NM_016608	51309	Xq21.33-q22.2	Hs.9728	8	binding membrane integral to membrane
205841_at	-0.814	5.502	-3.760	1.850e-03	0.084	-1.163	JAK2	Janus kinase 2	9	4975244	NM_004972	3717	9p24	Hs.656213	588	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding ATP binding nucleus cytoplasm cytoskeleton caveola apoptosis cell motion enzyme linked receptor protein signaling pathway tyrosine phosphorylation of STAT protein STAT protein nuclear translocation mesoderm development negative regulation of cell proliferation positive regulation of phosphoinositide 3-kinase cascade membrane transferase activity myeloid cell differentiation SH2 domain binding positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of DNA binding response to antibiotic positive regulation of peptidyl-tyrosine phosphorylation JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway	Chemokine signaling pathway Jak-STAT signaling pathway Adipocytokine signaling pathway
217741_s_at	-0.877	8.246	-3.759	1.856e-03	0.084	-1.166	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AW471220	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
228434_at	0.566	8.607	3.759	1.856e-03	0.084	-1.166	BTNL9	butyrophilin-like 9	5	180399830	AA806965	153579	5q35.3	Hs.546502	4	membrane integral to membrane
210785_s_at	0.423	3.943	3.757	1.861e-03	0.084	-1.168	C1orf38	chromosome 1 open reading frame 38	1	28071641	AB035482	9473	1p35.3	Hs.10649	8	cell adhesion
236887_at	-0.474	3.981	-3.757	1.861e-03	0.084	-1.168	KIN	KIN, antigenic determinant of recA protein homolog (mouse)	10	-7837372	AA768850	22944	10p15-p14	Hs.397918	17	DNA binding double-stranded DNA binding RNA binding intracellular nucleus cytoplasm DNA replication DNA repair DNA recombination mRNA processing response to DNA damage stimulus zinc ion binding nuclear matrix interspecies interaction between organisms metal ion binding
227812_at	-0.820	4.416	-3.757	1.861e-03	0.084	-1.169	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	13	23042722, 23051638	BF432648	55504	13q12.11-q12.3	Hs.149168	14	receptor activity tumor necrosis factor receptor activity protein binding mitochondrion apoptosis induction of apoptosis JNK cascade membrane integral to membrane	Cytokine-cytokine receptor interaction
230047_at	0.521	3.728	3.755	1.869e-03	0.085	-1.172	FLJ32810	Rho-type GTPase-activating protein FLJ32810	11	100063616	BF439533	143872	11q22.1	Hs.269837	2	GTPase activator activity intracellular signal transduction
205206_at	-1.063	7.950	-3.754	1.875e-03	0.085	-1.175	KAL1	Kallmann syndrome 1 sequence	X	-8456914	NM_000216	3730	Xp22.32	Hs.521869	35	serine-type endopeptidase inhibitor activity extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix extracellular space chemotaxis cell adhesion axon guidance cell surface peptidase inhibitor activity
227796_at	-0.437	6.329	-3.754	1.875e-03	0.085	-1.176	ZFP62	zinc finger protein 62 homolog (mouse)	5	-180207218, -12668	AW157773	643836	5q35.3	Hs.509227 Hs.719290	6	nucleic acid binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
223298_s_at	0.740	10.065	3.753	1.877e-03	0.085	-1.176	NT5C3	5'-nucleotidase, cytosolic III	7	-33020266, -33020266	AF312735	51251	7p14.3	Hs.487933	22	nucleotide binding magnesium ion binding cytoplasm endoplasmic reticulum pyrimidine nucleoside metabolic process 5'-nucleotidase activity 5'-nucleotidase activity 2'-phosphotransferase activity 2'-phosphotransferase activity nucleotide metabolic process hydrolase activity	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
224333_s_at	0.471	8.570	3.752	1.882e-03	0.085	-1.179	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	AB049940	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
238465_at	1.166	5.872	3.752	1.882e-03	0.085	-1.179	C5orf35	chromosome 5 open reading frame 35	5	56240859	AI265933	133383	5q11.2	Hs.85950	1
226994_at	-0.549	7.892	-3.752	1.883e-03	0.085	-1.179	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	16	-45546774	AW057513	10294	16q12.1	Hs.368078	15	protein folding zinc ion binding positive regulation of cell proliferation membrane heat shock protein binding metal ion binding unfolded protein binding
227369_at	-0.643	7.791	-3.751	1.886e-03	0.085	-1.181	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	AW771919	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
217882_at	-0.584	10.571	-3.751	1.886e-03	0.085	-1.181	TMEM111	transmembrane protein 111	3	-9980635	NM_018447	55831	3p25.3	Hs.475392	6	molecular_function cellular_component biological_process membrane integral to membrane
224733_at	0.418	5.900	3.750	1.887e-03	0.085	-1.182	CMTM3	CKLF-like MARVEL transmembrane domain containing 3	16	65195702, 65195713, 65196067	AL574900	123920	16q21	Hs.298198	7	cytokine activity extracellular space chemotaxis membrane integral to membrane
230560_at	0.553	5.350	3.750	1.888e-03	0.085	-1.182	STXBP6	syntaxin binding protein 6 (amisyn)	14	-24351143	N21096	29091	14q12	Hs.508958	6	cytoplasm membrane integral to membrane vesicle-mediated transport
222394_at	-0.496	7.107	-3.749	1.893e-03	0.085	-1.184	PDCD6IP	programmed cell death 6 interacting protein	3	33815069, 33815069, 33845133	BG484789	10015	3p22.3	Hs.475896	65	protein binding cytoplasm centrosome cytosol apoptosis cell cycle protein transport melanosome interspecies interaction between organisms cell division	Endocytosis
221537_at	0.249	6.785	3.746	1.906e-03	0.085	-1.190	PLXNA1	plexin A1	3	128190191	T16388	5361	3q21.3	Hs.432329	18	receptor activity protein binding cellular_component intracellular membrane fraction signal transduction multicellular organismal development membrane integral to membrane semaphorin receptor activity	Axon guidance
207677_s_at	0.507	3.661	3.745	1.909e-03	0.085	-1.192	NCF4	neutrophil cytosolic factor 4, 40kDa	22	35586975	NM_013416	4689	22q13.1	Hs.474781	51	cytoplasm cytosol immune response cell communication membrane phosphoinositide binding NADPH oxidase complex protein dimerization activity oxidation reduction	Leukocyte transendothelial migration
213614_x_at	1.175	11.708	3.744	1.912e-03	0.085	-1.193	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	BE786672	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
217943_s_at	-0.625	8.997	-3.744	1.912e-03	0.085	-1.193	MAP7D1	MAP7 domain containing 1	1	36394389	NM_018067	55700	1p34.3	Hs.700595	7	spindle
219959_at	1.203	5.116	3.743	1.915e-03	0.085	-1.195	MOCOS	molybdenum cofactor sulfurase	18	32021477	NM_017947	55034	18q12	Hs.405028	10	cellular_component Mo-molybdopterin cofactor biosynthetic process metabolic process Mo-molybdopterin cofactor sulfurase activity lyase activity molybdenum ion binding pyridoxal phosphate binding molybdopterin cofactor metabolic process
207564_x_at	-0.682	6.670	-3.743	1.918e-03	0.086	-1.196	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	70669657	NM_003605	8473	Xq13	Hs.405410	47	protein binding nucleus cytoplasm cytosol protein amino acid O-linked glycosylation signal transduction response to nutrient acetylglucosaminyltransferase activity transferase activity, transferring glycosyl groups MLL5-L complex	O-Glycan biosynthesis Metabolic pathways
208933_s_at	0.375	5.692	3.742	1.919e-03	0.086	-1.197	LGALS8	lectin, galactoside-binding, soluble, 8	1	234748187, 234753361, 234753699	AI659005	3964	1q42-q43	Hs.4082 Hs.708114	29	sugar binding extracellular space cytoplasm
232231_at	0.556	3.776	3.742	1.922e-03	0.086	-1.198	RUNX2	runt-related transcription factor 2	6	45404031, 45497891	AL353944	860	6p21	Hs.535845	152	osteoblast differentiation transcription factor activity RNA polymerase II transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent negative regulation of transcription transcription activator activity
224579_at	2.607	7.933	3.741	1.923e-03	0.086	-1.199	SLC38A1	solute carrier family 38, member 1	12	-44863107	BF247552	81539	12q13.11	Hs.694701	11	sodium:amino acid symporter activity membrane fraction plasma membrane ion transport sodium ion transport glutamine transport L-glutamine transmembrane transporter activity symporter activity integral to membrane axon sodium ion binding
206544_x_at	-0.762	7.914	-3.740	1.931e-03	0.086	-1.202	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	9	2005341	NM_003070	6595	9p22.3	Hs.298990	63	nucleotide binding DNA binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm chromatin remodeling regulation of transcription from RNA polymerase II promoter DNA-dependent ATPase activity positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter SWI/SNF complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
201222_s_at	-0.524	8.610	-3.738	1.935e-03	0.086	-1.205	RAD23B	RAD23 homolog B (S. cerevisiae)	9	109085364	AL527365	5887	9q31.2	Hs.521640	54	nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex	Nucleotide excision repair
210275_s_at	-0.746	10.431	-3.738	1.938e-03	0.086	-1.206	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AF062347	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
213661_at	0.599	5.784	3.737	1.939e-03	0.086	-1.207	PAMR1	peptidase domain containing associated with muscle regeneration 1	11	-35409951	AI671186	25891	11p13	Hs.55044	4	catalytic activity serine-type endopeptidase activity extracellular region proteolysis
218919_at	-0.403	7.043	-3.737	1.940e-03	0.086	-1.207	ZFAND1	zinc finger, AN1-type domain 1	8	-82776512	NM_024699	79752	8q21.13	Hs.655453	4	zinc ion binding metal ion binding
215293_s_at	0.260	6.207	3.737	1.942e-03	0.086	-1.208	PGAP2	post-GPI attachment to proteins 2	11	3775529, 3775624, 3775707, 3775765, 3785815, 3786341	AL049261	27315	11p15.5	Hs.133968	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus GPI anchor biosynthetic process protein transporter activity membrane integral to membrane
209112_at	-0.582	9.602	-3.736	1.945e-03	0.086	-1.210	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	12	12761568	BC001971	1027	12p13.1-p12	Hs.238990	442	regulation of cyclin-dependent protein kinase activity G1/S transition of mitotic cell cycle protein kinase inhibitor activity cyclin-dependent protein kinase inhibitor activity transforming growth factor beta receptor, cytoplasmic mediator activity protein binding nucleus cytoplasm cytosol induction of apoptosis cell cycle cell cycle arrest negative regulation of cell proliferation negative regulation of cell growth negative regulation of gene-specific transcription negative regulation of kinase activity negative regulation of phosphorylation autophagic cell death	ErbB signaling pathway Cell cycle Pathways in cancer Prostate cancer Chronic myeloid leukemia Small cell lung cancer
205967_at	0.416	8.951	3.735	1.949e-03	0.086	-1.212	HIST1H4C	histone cluster 1, H4c	6	26212154	NM_003542	8364	6p21.3	Hs.46423	10		Systemic lupus erythematosus
209406_at	-0.465	8.221	-3.734	1.951e-03	0.086	-1.212	BAG2	BCL2-associated athanogene 2	6	57145062	AF095192	9532	6p12.1-p11.2	Hs.719303	16	protein binding protein folding apoptosis protein metabolic process
215116_s_at	0.434	5.277	3.734	1.953e-03	0.086	-1.213	DNM1	dynamin 1	9	130005483	AF035321	1759	9q34	Hs.522413	77	nucleotide binding motor activity GTPase activity protein binding GTP binding cytoplasm cytoskeleton microtubule receptor-mediated endocytosis hydrolase activity	Endocytosis Fc gamma R-mediated phagocytosis
203100_s_at	-0.599	5.704	-3.733	1.956e-03	0.086	-1.215	CDYL	chromodomain protein, Y-like	6	4651391, 4721678, 4781330, 4835224	NM_004824	9425	6p25.1	Hs.269092	8	chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription
209451_at	-0.633	7.938	-3.733	1.957e-03	0.086	-1.215	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	U59863	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
229088_at	0.568	4.195	3.733	1.958e-03	0.086	-1.216	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	6	132170848	BF591996	5167	6q22-q23	Hs.527295	107	nucleic acid binding phosphodiesterase I activity nucleotide diphosphatase activity nucleotide diphosphatase activity scavenger receptor activity insulin receptor binding protein binding ATP binding extracellular space plasma membrane plasma membrane generation of precursor metabolites and energy phosphate metabolic process immune response metabolic process nucleoside triphosphate catabolic process cell surface integral to membrane basolateral plasma membrane hydrolase activity polysaccharide binding negative regulation of cell growth regulation of bone mineralization inorganic diphosphate transport cellular phosphate ion homeostasis sequestering of triglyceride biomineral formation negative regulation of protein amino acid autophosphorylation cellular response to insulin stimulus protein homodimerization activity negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process negative regulation of glucose import negative regulation of insulin receptor signaling pathway metal ion binding nucleoside-triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process 3'-phosphoadenosine 5'-phosphosulfate binding	Purine metabolism Starch and sucrose metabolism Riboflavin metabolism Nicotinate and nicotinamide metabolism Pantothenate and CoA biosynthesis Metabolic pathways
222128_at	0.491	4.525	3.732	1.959e-03	0.086	-1.216	NSUN6	NOL1/NOP2/Sun domain family, member 6	10	-18874269	U80764	221078	10p12.31	Hs.396175	4	RNA binding methyltransferase activity transferase activity
222586_s_at	-1.041	7.612	-3.732	1.960e-03	0.086	-1.217	OSBPL11	oxysterol binding protein-like 11	3	-126730397	AI884890	114885	3q21	Hs.477440	12	lipid transport steroid metabolic process
212251_at	-0.522	9.406	-3.730	1.968e-03	0.086	-1.220	MTDH	metadherin	8	98725582	AI972475	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
226364_at	0.432	5.856	3.730	1.969e-03	0.086	-1.221	HIP1	huntingtin interacting protein 1	7	-75001344	AU145049	3092	7q11.23	Hs.329266 Hs.619089	31	actin binding structural constituent of cytoskeleton membrane fraction nucleus cytoplasm Golgi apparatus cytoskeleton endocytosis induction of apoptosis activation of caspase activity cell death membrane cell differentiation clathrin binding clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding regulation of apoptosis regulation of transcription positive regulation of receptor-mediated endocytosis clathrin coat assembly	Huntington's disease
244428_at	0.360	4.351	3.729	1.973e-03	0.086	-1.223	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	2	-25357824, -25309348, -25309348, -25309348	AW572279	1788	2p23	Hs.515840	54	euchromatin DNA binding DNA (cytosine-5-)-methyltransferase activity protein binding nucleus cytoplasm DNA methylation genetic imprinting methyltransferase activity zinc ion binding nuclear matrix transferase activity metal ion binding	Cysteine and methionine metabolism Metabolic pathways
1559870_at	0.363	5.947	3.726	1.987e-03	0.087	-1.229	LOC100129129	hypothetical protein LOC100129129	8		BC038546	100129129	8p23.1	Hs.662094
213624_at	-0.667	8.799	-3.725	1.988e-03	0.087	-1.230	SMPDL3A	sphingomyelin phosphodiesterase, acid-like 3A	6	123151669	AA873600	10924	6q22.31	Hs.486357	5	sphingomyelin phosphodiesterase activity protein binding extracellular region extracellular space sphingomyelin catabolic process metabolic process hydrolase activity, acting on glycosyl bonds
210845_s_at	0.302	5.166	3.725	1.989e-03	0.087	-1.230	PLAUR	plasminogen activator, urokinase receptor	19	-48844571, -48842087	U08839	5329	19q13	Hs.466871	234	extracellular region plasma membrane plasma membrane cell motion chemotaxis signal transduction blood coagulation cell surface integral to membrane attachment of GPI anchor to protein extrinsic to membrane enzyme binding regulation of proteolysis U-plasminogen activator receptor activity anchored to membrane skeletal muscle regeneration	Complement and coagulation cascades
213911_s_at	-0.536	9.588	-3.722	2.001e-03	0.087	-1.236	H2AFZ	H2A histone family, member Z	4	-101088266	BF718636	3015	4q24	Hs.119192	37	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
212829_at	0.377	5.744	3.722	2.003e-03	0.087	-1.237	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	10	-22863771	BE878277	5305	10p12.2	Hs.57079	24	nucleotide binding ATP binding cellular_component kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity phosphorylation transferase activity phosphatidylinositol metabolic process	Inositol phosphate metabolism Phosphatidylinositol signaling system Regulation of actin cytoskeleton
202751_at	-0.478	3.722	-3.721	2.004e-03	0.087	-1.237	TFIP11	tuftelin interacting protein 11	22	-25217894	NM_012143	24144	22q12.1	Hs.20225	19	nucleic acid binding protein binding proteinaceous extracellular matrix intracellular nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing nuclear speck biomineral formation
239272_at	0.271	4.882	3.721	2.006e-03	0.087	-1.238	MMP28	matrix metallopeptidase 28	17	-31129621, -31116988	AI927208	79148	17q11-q21.1	Hs.380710	13	metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix proteolysis metabolic process peptidase activity zinc ion binding
200738_s_at	-0.677	11.446	-3.721	2.007e-03	0.087	-1.239	PGK1	phosphoglycerate kinase 1	X	77246321	NM_000291	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
223089_at	-0.847	7.513	-3.720	2.008e-03	0.087	-1.239	VEZT	vezatin, adherens junctions transmembrane protein	12	94135652	AI805297	55591	12q22	Hs.24135	8	acrosomal vesicle nucleus plasma membrane adherens junction integral to membrane cell junction
211038_s_at	-0.509	7.760	-3.717	2.023e-03	0.087	-1.246	CROCCL1	ciliary rootlet coiled-coil, rootletin-like 1	1	-16817339	BC006312	84809	1p36.13	Hs.631865	2
208306_x_at	0.713	8.814	3.717	2.023e-03	0.087	-1.246	HLA-DRB4	major histocompatibility complex, class II, DR beta 4	6		NM_021983	3126	6p21.3	Hs.534322 Hs.696211 Hs.716081	135	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II integral to plasma membrane immune response signal transduction pathogenesis membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
226660_at	-0.580	8.434	-3.717	2.024e-03	0.087	-1.246	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	AI142096	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
204892_x_at	1.251	11.831	3.715	2.032e-03	0.088	-1.250	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	NM_001402	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
206241_at	-0.764	5.551	-3.714	2.035e-03	0.088	-1.251	KPNA5	karyopherin alpha 5 (importin alpha 6)	6	117109059	NM_002269	3841	6q22.1	Hs.182971	46	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
226251_at	-0.477	5.926	-3.710	2.050e-03	0.088	-1.259	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	AW295549	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
240602_at	-0.447	2.954	-3.710	2.051e-03	0.088	-1.259	HBS1L	HBS1-like (S. cerevisiae)	6	-135398687, -135323215, -135323213	AI801875	10767	6q23-q24	Hs.378532	12	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation signal transduction
34408_at	-0.565	10.274	-3.710	2.053e-03	0.088	-1.260	RTN2	reticulon 2	19	-50680389, -50680389, -50680389	AF004222	6253	19q13.32	Hs.47517	10	signal transducer activity endoplasmic reticulum signal transduction membrane integral to membrane integral to endoplasmic reticulum membrane
200830_at	-0.338	9.581	-3.709	2.058e-03	0.088	-1.262	PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	3	185499715	NM_002808	5708	3q27.1	Hs.518464	45	proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
220753_s_at	0.441	6.227	3.708	2.059e-03	0.088	-1.262	CRYL1	crystallin, lambda 1	13	-19875805	NM_015974	51084	13q12.11	Hs.370703	6	binding cytosol fatty acid metabolic process metabolic process oxidoreductase activity protein homodimerization activity L-gulonate 3-dehydrogenase activity NAD binding
238877_at	-0.570	8.373	-3.708	2.059e-03	0.088	-1.262	EYA4	eyes absent homolog 4 (Drosophila)	6	133604187	BE674583	2070	6q23	Hs.596680	15	magnesium ion binding protein tyrosine phosphatase activity nucleus cytoplasm DNA repair response to DNA damage stimulus multicellular organismal development visual perception metabolic process anatomical structure morphogenesis chromatin modification hydrolase activity regulation of transcription
213317_at	-0.614	11.228	-3.708	2.061e-03	0.088	-1.263	CLIC5	chloride intracellular channel 5	6	-45974165, -45974165	AL049313	53405	6p21.1-p12.1	Hs.485489	15	voltage-gated ion channel activity voltage-gated chloride channel activity protein binding insoluble fraction cytoplasm Golgi apparatus centrosome cell cortex ion transport chloride transport female pregnancy actin cytoskeleton membrane integral to membrane chloride ion binding chloride channel complex
202582_s_at	-0.425	9.914	-3.707	2.063e-03	0.088	-1.264	RANBP9	RAN binding protein 9	6	-13729708	AF306510	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
212295_s_at	2.090	5.968	3.707	2.064e-03	0.088	-1.265	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	13	-28981551	AA148507	6541	13q12-q14	Hs.14846	23	receptor activity integral to plasma membrane transport amino acid transport amino acid transmembrane transporter activity arginine transmembrane transporter activity arginine transport membrane
208203_x_at	-0.289	5.783	-3.706	2.067e-03	0.088	-1.266	KIR2DS5	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5	19	240800	NM_014513	3810	19q13.4	Hs.714920	48	receptor activity plasma membrane integral to plasma membrane immune response HLA-C specific inhibitory MHC class I receptor activity	Antigen processing and presentation Natural killer cell mediated cytotoxicity
202166_s_at	-0.779	9.095	-3.706	2.068e-03	0.088	-1.266	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	3	-196722511	NM_006241	5504	3q29	Hs.535731 Hs.706920	22	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy regulation of signal transduction regulation of phosphoprotein phosphatase activity
202778_s_at	-0.415	6.655	-3.706	2.071e-03	0.088	-1.268	ZMYM2	zinc finger, MYM-type 2	13	19430809	NM_003453	7750	13q11-q12	Hs.644041	29	protein binding cellular_component nucleus biological_process zinc ion binding PML body ubiquitin conjugating enzyme binding regulation of transcription metal ion binding
201312_s_at	0.607	7.360	3.704	2.078e-03	0.088	-1.271	SH3BGRL	SH3 domain binding glutamic acid-rich protein like	X	80343958	NM_003022	6451	Xq13.3	Hs.108029	13	SH3/SH2 adaptor activity nucleus cytoplasm SH3 domain binding
210027_s_at	0.347	9.080	3.702	2.084e-03	0.088	-1.274	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	14	19993129	M80261	328	14q11.2-q12	Hs.73722	235	magnesium ion binding DNA binding transcription coactivator activity transcription corepressor activity DNA-(apurinic or apyrimidinic site) lyase activity endodeoxyribonuclease activity ribonuclease H activity phosphodiesterase I activity uracil DNA N-glycosylase activity protein binding intracellular nucleus nucleoplasm cytoplasm endoplasmic reticulum centrosome ribosome base-excision repair transcription from RNA polymerase II promoter response to DNA damage stimulus 3'-5' exonuclease activity oxidoreductase activity lyase activity cell redox homeostasis perinuclear region of cytoplasm regulation of DNA binding	Base excision repair
224437_s_at	-0.482	8.207	-3.702	2.084e-03	0.088	-1.274	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	BC005937	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
229732_at	0.563	4.007	3.702	2.087e-03	0.088	-1.275	ZNF823	zinc finger protein 823	19	-11693079	AI417785	55552	19p13.2	Hs.142167	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221875_x_at	0.557	8.396	3.701	2.088e-03	0.088	-1.275	HLA-F	major histocompatibility complex, class I, F	6	29799095, 29799095, 1143812, 1143812, 945922, 945922	AW514210	3134	6p21.3	Hs.519972	68	antigen processing and presentation of peptide antigen via MHC class I immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
202429_s_at	-0.716	8.493	-3.701	2.090e-03	0.088	-1.276	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	AL353950	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
204278_s_at	-0.565	8.237	-3.701	2.091e-03	0.088	-1.277	EBAG9	estrogen receptor binding site associated, antigen, 9	8	110621104, 110621485	NM_004215	9166	8q23	Hs.409368	55	regulation of cell growth soluble fraction Golgi apparatus plasma membrane focal adhesion apoptosis integral to membrane apoptotic protease activator activity
221073_s_at	0.333	6.206	3.700	2.093e-03	0.088	-1.277	NOD1	nucleotide-binding oligomerization domain containing 1	7	-30430667	NM_006092	10392	7p15-p14	Hs.405153	72	nucleotide binding ATP binding intracellular cytoplasm induction of apoptosis activation of caspase activity inflammatory response intracellular signaling cascade caspase activator activity detection of bacterium positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade interleukin-8 biosynthetic process identical protein binding peptidoglycan binding regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JNK cascade CARD domain binding defense response to Gram-positive bacterium protein oligomerization positive regulation of ERK1 and ERK2 cascade	Epithelial cell signaling in Helicobacter pylori infection
210153_s_at	0.467	7.460	3.700	2.094e-03	0.088	-1.278	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	18	46659432	M55905	4200	18q21 6p25-p24	Hs.233119	24	malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide
225071_at	-0.463	6.013	-3.700	2.094e-03	0.088	-1.278	NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	6	118103309	BG168247	116150	6q22.1	Hs.289008	6	angiogenesis molecular_function receptor activity cellular_component multicellular organismal development biological_process membrane integral to membrane transferase activity, transferring alkyl or aryl (other than methyl) groups cell differentiation
223490_s_at	-0.418	5.070	-3.699	2.097e-03	0.088	-1.279	EXOSC3	exosome component 3	9	-37770307, -37770307	AF281132	51010	9p11	Hs.602571 Hs.713483	12	3'-5'-exoribonuclease activity nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing hydrolase activity	RNA degradation
1552732_at	-1.329	10.048	-3.699	2.097e-03	0.088	-1.280	ABRA	actin-binding Rho activating protein	8	-107840886	AL832152	137735	8q23.1	Hs.374668	12	protein import into nucleus, translocation transcription coactivator activity actin binding cytoplasm plasma membrane protein transport actin cytoskeleton sarcomere positive regulation of Rho protein signal transduction positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription factor activity intracellular protein transmembrane transport
223805_at	-0.578	8.468	-3.699	2.099e-03	0.088	-1.280	OSBPL6	oxysterol binding protein-like 6	2	178767619, 178893216	AF323728	114880	2q31-q32.1	Hs.318775	7	lipid transport steroid metabolic process
209595_at	-0.664	6.619	-3.699	2.099e-03	0.088	-1.280	GTF2F2	general transcription factor IIF, polypeptide 2, 30kDa	13	44592630	BC001771	2963	13q14	Hs.654582	50	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding helicase activity ATP binding nucleus nucleoplasm transcription factor TFIIF complex cytoskeleton transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter ATP-dependent helicase activity general RNA polymerase II transcription factor activity hydrolase activity regulation of transcription	Basal transcription factors
225946_at	-0.472	6.897	-3.697	2.106e-03	0.088	-1.283	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	12	26003235	BG484552	11228	12p12.3	Hs.696433	8	signal transduction
224467_s_at	0.310	7.400	3.696	2.110e-03	0.089	-1.285	PDCD2L	programmed cell death 2-like	19	39587142	BC006146	84306	19q13.11	Hs.515344	5	cytoplasm
201066_at	0.351	11.243	3.695	2.116e-03	0.089	-1.288	CYC1	cytochrome c-1	8	145221947	NM_001916	1537	8q24.3	Hs.289271	23	mitochondrion mitochondrial inner membrane transport membrane integral to membrane heme binding electron transport chain electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity metal ion binding respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
223960_s_at	-0.390	6.790	-3.695	2.117e-03	0.089	-1.288	C16orf5	chromosome 16 open reading frame 5	16	-4500677	AF195661	29965	16p13.3	Hs.654653	6	molecular_function nucleus apoptosis induction of apoptosis biological_process tumor necrosis factor-mediated signaling pathway DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
204220_at	0.391	6.305	3.693	2.123e-03	0.089	-1.291	GMFG	glia maturation factor, gamma	19	-44510839	NM_004877	9535	19q13.2	Hs.5210	12	actin binding protein kinase inhibitor activity intracellular protein amino acid phosphorylation enzyme activator activity growth factor activity
218214_at	-0.392	7.224	-3.693	2.125e-03	0.089	-1.292	C12orf44	chromosome 12 open reading frame 44	12	50750024	NM_021934	60673	12q13.13	Hs.9911	4
228214_at	-0.771	7.401	-3.692	2.130e-03	0.089	-1.294	SOX6	SRY (sex determining region Y)-box 6	11	-15944571, -15944571, -15944571	AW242286	55553	11p15.3	Hs.368226	24	transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent multicellular organismal development muscle organ development
228765_at	-0.619	8.877	-3.692	2.131e-03	0.089	-1.294	GTF2IRD2	GTF2I repeat domain containing 2	7	-73848419	BG032651	84163	7q11.23	Hs.647017 Hs.647039	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription
212638_s_at	-0.761	10.114	-3.691	2.135e-03	0.089	-1.296	WWP1	WW domain containing E3 ubiquitin protein ligase 1	8	87424109	BF131791	11059	8q21	Hs.655189	30	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding intracellular protein modification process signal transduction central nervous system development negative regulation of transcription protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process interspecies interaction between organisms entry of virus into host cell	Ubiquitin mediated proteolysis Endocytosis
200658_s_at	0.397	8.490	3.690	2.136e-03	0.089	-1.296	PHB	prohibitin	17	-44836418	AL560017	5245	17q21	Hs.514303	70	protein binding nucleus nucleoplasm mitochondrion mitochondrial inner membrane integral to plasma membrane DNA replication signal transduction negative regulation of cell proliferation membrane negative regulation of transcription transcription activator activity transcription repressor activity histone deacetylation regulation of apoptosis
220129_at	1.067	4.303	3.690	2.137e-03	0.089	-1.297	SOHLH2	spermatogenesis and oogenesis specific basic helix-loop-helix 2	13	-35640346	NM_017826	54937	13q13.3	Hs.124519	4	DNA binding nucleus multicellular organismal development spermatogenesis cell differentiation transcription regulator activity regulation of transcription oogenesis
218977_s_at	0.466	5.319	3.690	2.139e-03	0.089	-1.298	TRNAU1AP	tRNA selenocysteine 1 associated protein 1	1	28752115	NM_017846	54952	1p35.3	Hs.533626	5	nucleotide binding selenocysteine incorporation RNA binding nucleus cytoplasm translation
203803_at	-1.003	7.593	-3.690	2.139e-03	0.089	-1.298	PCYOX1	prenylcysteine oxidase 1	2	70338734	N45309	51449	2p13.3	Hs.567502	13	prenylcysteine oxidase activity binding lysosome oxidoreductase activity prenylated protein catabolic process prenylcysteine catabolic process very-low-density lipoprotein particle oxidation reduction
238557_at	0.312	4.484	3.689	2.142e-03	0.089	-1.299	LOC100144603	hypothetical transcript	22	49368320	R58282	100144603	22q13.33	Hs.657275	1
227862_at	0.556	5.362	3.689	2.143e-03	0.089	-1.300	TRNP1	TMF1-regulated nuclear protein 1	1	27192781	AA037766	388610	1p36.11	Hs.355747	2	nucleus cell cycle
228900_at	0.406	5.374	3.689	2.145e-03	0.089	-1.300	CYTSB	cytospin B	17	19930926, 19930926, 19999993, 19999993	AW511308	92521	17p11.2	Hs.431045	9	nucleus
213064_at	-0.589	6.460	-3.688	2.147e-03	0.089	-1.301	ZC3H14	zinc finger CCCH-type containing 14	14	88099005, 88099443, 88130482	N64802	79882	14q31.3	Hs.325846	7	RNA binding nucleus zinc ion binding metal ion binding
1569157_s_at	0.754	4.499	3.687	2.152e-03	0.089	-1.303	ZNF846	zinc finger protein 846	19	-9729150	BC037359	162993	19p13.2	Hs.665717	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204732_s_at	-0.610	6.011	-3.687	2.152e-03	0.089	-1.304	TRIM23	tripartite motif-containing 23	5	-64921262	AI021991	373	5q12.3	Hs.792	14	Golgi membrane nucleotide binding GTPase activity ubiquitin-protein ligase activity protein binding GTP binding intracellular nucleus cytoplasm lysosomal membrane Golgi apparatus small GTPase mediated signal transduction enzyme activator activity zinc ion binding membrane protein ubiquitination GDP binding metal ion binding
223852_s_at	-0.482	7.293	-3.686	2.154e-03	0.089	-1.304	STK40	serine/threonine kinase 40	1	-36577811	BC005169	83931	1p34.3	Hs.471768	11	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity
218695_at	0.624	6.821	3.686	2.155e-03	0.089	-1.305	EXOSC4	exosome component 4	8	145205509	NM_019037	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
224818_at	-0.452	8.719	-3.686	2.155e-03	0.089	-1.305	SORT1	sortilin 1	1	-109653714	BE622952	6272	1p21.3-p13.1	Hs.485195 Hs.703487	47	ossification receptor activity nucleus lysosome early endosome endoplasmic reticulum microsome Golgi apparatus plasma membrane coated pit transport Golgi to endosome transport endocytosis neuropeptide signaling pathway multicellular organismal development endosome to lysosome transport induction of apoptosis by extracellular signals cell surface nerve growth factor receptor activity regulation of gene expression myotube differentiation integral to membrane cytoplasmic membrane-bounded vesicle vesicle organization enzyme binding clathrin-coated vesicle cell differentiation neurotensin receptor activity, non-G-protein coupled endosome transport via multivesicular body sorting pathway response to insulin stimulus negative regulation of apoptosis glucose import nerve growth factor receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity	Lysosome Neurotrophin signaling pathway
1569256_a_at	-0.354	5.689	-3.685	2.161e-03	0.089	-1.307	FAM43B	family with sequence similarity 43, member B	1	20751518	BC015675	163933	1p36.12	Hs.429179	3
205839_s_at	0.443	5.250	3.682	2.171e-03	0.089	-1.312	BZRAP1	benzodiazapine receptor (peripheral) associated protein 1	17	-53733592	NM_004758	9256	17q22-q23	Hs.112499	6	cytoplasm mitochondrion biological_process benzodiazepine receptor binding
239357_at	-1.131	5.476	-3.681	2.176e-03	0.089	-1.314	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	3	-10340706	AA002211	491	3p25.3	Hs.268942	30	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding cytoplasm plasma membrane ATP biosynthetic process cation transport calcium ion transport sensory perception of sound metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances neuron differentiation	Calcium signaling pathway
227696_at	0.743	8.541	3.681	2.178e-03	0.089	-1.315	EXOSC6	exosome component 6	16	-68841634	AI701408	118460	16q22.1	Hs.660633 Hs.719211	9	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
213737_x_at	0.350	8.885	3.680	2.181e-03	0.089	-1.316	GOLGA9P	golgi autoantigen, golgin subfamily a, 9 pseudogene	15	20806682	AI620911	283796	15q11.2	Hs.375441	2
238047_at	2.432	5.314	3.678	2.191e-03	0.090	-1.320	RP13-102H20.1	hypothetical protein FLJ30058	X	130019896	AA405456	158763	Xq26.1	Hs.22905	5	intracellular signal transduction
212188_at	0.832	7.397	3.677	2.195e-03	0.090	-1.322	KCTD12	potassium channel tetramerisation domain containing 12	13	-76352304	AA551075	115207	13q22.3	Hs.644125	14	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
210102_at	0.483	4.548	3.675	2.204e-03	0.090	-1.326	VWA5A	von Willebrand factor A domain containing 5A	11	123491320, 123491320	BC001234	4013	11q23	Hs.152944	5
201503_at	-0.605	9.351	-3.674	2.208e-03	0.090	-1.327	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	BG500067	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
222488_s_at	-0.356	9.175	-3.674	2.211e-03	0.090	-1.329	DCTN4	dynactin 4 (p62)	5	-150068502, -150068502	BE218028	51164	5q31-q32	Hs.675564	7	nucleus cytoplasm centrosome cytoskeleton protein N-terminus binding	Huntington's disease
212990_at	-0.525	5.635	-3.673	2.212e-03	0.090	-1.329	SYNJ1	synaptojanin 1	21	-32922939, -32922939	AB020717	8867	21q22.2	Hs.473632	31	RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity cytoplasm dephosphorylation hydrolase activity synaptic vesicle endocytosis	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
205896_at	0.635	4.695	3.673	2.213e-03	0.090	-1.329	SLC22A4	solute carrier family 22 (organic cation/ergothioneine transporter), member 4	5	131658043	NM_003059	6583	5q31.1	Hs.310591	79	nucleotide binding transporter activity protein binding ATP binding mitochondrion plasma membrane integral to plasma membrane triglyceride metabolic process ion transport sodium ion transport body fluid secretion secondary active organic cation transmembrane transporter activity carnitine metabolic process ion transmembrane transporter activity carnitine transporter activity symporter activity cation:cation antiporter activity quaternary ammonium group transport carnitine transport apical plasma membrane PDZ domain binding sodium ion binding
1553960_at	0.678	7.328	3.672	2.218e-03	0.090	-1.332	SNX21	sorting nexin family member 21	20	43895876	CA447177	90203	20q13.12	Hs.472854	8	protein binding cell communication protein transport phosphoinositide binding
238625_at	-2.255	4.577	-3.670	2.227e-03	0.090	-1.335	C1orf168	chromosome 1 open reading frame 168	1	-56957064	AI452457	199920	1p32.2	Hs.437655	3
230822_at	0.349	4.496	3.668	2.236e-03	0.091	-1.339	TMEM61	transmembrane protein 61	1	55219052	AI766925	199964	1p32.3	Hs.663950	3	membrane integral to membrane
218530_at	-0.577	8.336	-3.667	2.240e-03	0.091	-1.341	FHOD1	formin homology 2 domain containing 1	16	-65820792	NM_013241	29109	16q22	Hs.95231	25	actin binding protein binding nucleus cytoplasm cytoskeleton cellular component organization actin cytoskeleton organization
201899_s_at	-0.348	9.213	-3.667	2.241e-03	0.091	-1.341	UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	X	118592526, 118598325	NM_003336	7319	Xq24-q25	Hs.379466	16	nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination	Ubiquitin mediated proteolysis
225274_at	-0.730	9.882	-3.667	2.242e-03	0.091	-1.342	PCYOX1	prenylcysteine oxidase 1	2	70338734	BF247054	51449	2p13.3	Hs.567502	13	prenylcysteine oxidase activity binding lysosome oxidoreductase activity prenylated protein catabolic process prenylcysteine catabolic process very-low-density lipoprotein particle oxidation reduction
229110_at	0.919	3.472	3.667	2.243e-03	0.091	-1.342	LOC100128844	hypothetical protein LOC100128844	9		N50083	100128844	9p22.1	Hs.593150
230563_at	0.756	4.497	3.666	2.247e-03	0.091	-1.343	RASGEF1A	RasGEF domain family, member 1A	10	-43009989	BF446578	221002	10q11.21	Hs.125293	4	guanyl-nucleotide exchange factor activity intracellular regulation of small GTPase mediated signal transduction
242887_at	-0.441	4.686	-3.665	2.251e-03	0.091	-1.345	KCMF1	potassium channel modulatory factor 1	2	85051741	AI221300	56888	2p11.2	Hs.654968	7	intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
225939_at	-0.618	6.385	-3.665	2.252e-03	0.091	-1.345	EIF4E3	eukaryotic translation initiation factor 4E family member 3	3	-71811131, -71811131, -71811131, -71811131	AL161983	317649	3p14	Hs.581355	3	RNA binding translation initiation factor activity cytoplasm translational initiation regulation of translation
200711_s_at	-0.510	9.463	-3.664	2.253e-03	0.091	-1.346	SKP1	S-phase kinase-associated protein 1	5	-133519980	NM_003197	6500	5q31	Hs.171626 Hs.710433	63	protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
205388_at	-0.934	13.323	-3.662	2.264e-03	0.091	-1.350	TNNC2	troponin C type 2 (fast)	20	-43885261	NM_003279	7125	20q12-q13.11	Hs.182421	12	skeletal muscle contraction actin binding calcium ion binding troponin complex regulation of muscle contraction	Calcium signaling pathway
202034_x_at	-0.727	7.934	-3.661	2.268e-03	0.091	-1.352	RB1CC1	RB1-inducible coiled-coil 1	8	-53697570	NM_014781	9821	8q11	Hs.196102	29	liver development positive regulation of protein amino acid phosphorylation protein binding nucleus cell cycle JNK cascade heart development negative regulation of apoptosis regulation of transcription positive regulation of cell size
221743_at	-0.332	10.502	-3.661	2.268e-03	0.091	-1.352	CUGBP1	CUG triplet repeat, RNA binding protein 1	11	-47446520, -47446520, -47446520	AI472139	10658	11p11	Hs.632137	34	nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding
239390_at	-0.406	5.653	-3.659	2.278e-03	0.091	-1.356	GTDC1	glycosyltransferase-like domain containing 1	2	-144420052, -144420050	BE327650	79712	2q22.3	Hs.44780	3	biosynthetic process transferase activity, transferring glycosyl groups
236022_at	0.335	5.085	3.659	2.278e-03	0.091	-1.356	MYO19	myosin XIX	17	-31943030, -31925712, -31925711	AI650341	80179	17q12	Hs.302051	3	nucleotide binding motor activity actin binding ATP binding cytoplasm myosin complex
204161_s_at	-0.780	7.008	-3.659	2.279e-03	0.091	-1.357	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)	6	46205659	NM_014936	22875	6p21.1	Hs.643497	4	metabolic process membrane integral to membrane hydrolase activity
200794_x_at	-0.633	9.386	-3.656	2.294e-03	0.092	-1.363	DAZAP2	DAZ associated protein 2	12	49918774, 49918774	NM_014764	9802	12q12	Hs.369761	15	protein binding WW domain binding
214033_at	-0.470	5.924	-3.655	2.296e-03	0.092	-1.364	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	16	-16222544, -16150922	AI084637	368	16p13.1	Hs.442182	70	nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus	ABC transporters
201091_s_at	-0.551	7.916	-3.655	2.297e-03	0.092	-1.364	CBX3	chromobox homolog 3 (HP1 gamma homolog, Drosophila)	7	26207623, 26207848	BE748755	11335	7p15.2	Hs.381189 Hs.706294	45	condensed chromosome, centromeric region chromatin chromatin binding nucleus nuclear inner membrane polytene chromosome chromocenter nuclear euchromatin spindle chromatin assembly or disassembly chromatin remodeling negative regulation of transcription general transcriptional repressor activity enzyme binding protein domain specific binding nuclear centromeric heterochromatin
222380_s_at	0.428	6.494	3.655	2.298e-03	0.092	-1.365	PDCD6	programmed cell death 6	5	324735	AI907083	10016	5p15.33	Hs.50823	36	calcium ion binding nucleus endoplasmic reticulum apoptosis induction of apoptosis by extracellular signals membrane calcium-dependent protein binding response to calcium ion
224700_at	-0.728	9.174	-3.655	2.299e-03	0.092	-1.365	STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	3	31549494	BF221532	201595	3p23	Hs.475812	9	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum protein amino acid glycosylation membrane integral to membrane transferase activity	N-Glycan biosynthesis Metabolic pathways
220233_at	0.396	5.404	3.654	2.304e-03	0.092	-1.367	FBXO17	F-box protein 17	19	-44123881, -44123881	NM_024907	115290	19q13.2	Hs.531770	7	protein binding modification-dependent protein catabolic process protein catabolic process
228420_at	-0.260	5.780	-3.654	2.305e-03	0.092	-1.367	PDCD2	programmed cell death 2	6	-170732759, -170728374	AW590850	5134	6q27	Hs.367900	14	DNA binding protein binding nucleus cytoplasm apoptosis zinc ion binding metal ion binding
1555912_at	0.361	4.156	3.653	2.309e-03	0.092	-1.369	ST7OT1	ST7 overlapping transcript 1 (non-protein coding)	7	-116379736	AI016213	93653	7q31.1-q31.2	Hs.597516	1
238263_at	0.315	4.063	3.653	2.310e-03	0.092	-1.369	LOC285965	hypothetical protein LOC285965	7		AW590543	285965	7q35	Hs.642649
207705_s_at	0.712	6.329	3.649	2.328e-03	0.092	-1.377	NINL	ninein-like	20	-25381337	NM_025176	22981	20p11.22-p11.1	Hs.696157	13	calcium ion binding cytoplasm centrosome microtubule
212967_x_at	-0.443	9.824	-3.649	2.329e-03	0.092	-1.377	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AW148801	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
230068_s_at	0.310	3.912	3.648	2.331e-03	0.092	-1.378	PEG3	paternally expressed 3	19	-62013256, -62013256	W93046	5178	19q13.4	Hs.719209	18	nucleic acid binding transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent apoptosis zinc ion binding metal ion binding
226047_at	0.410	7.129	3.647	2.336e-03	0.093	-1.379	MRVI1	murine retrovirus integration site 1 homolog	11	-10551213, -10551213, -10551213	N66571	10335	11p15	Hs.501898	13	cytoplasm endoplasmic reticulum membrane membrane integral to membrane sarcoplasmic reticulum perinuclear region of cytoplasm	Vascular smooth muscle contraction
236994_at	-1.119	4.327	-3.647	2.337e-03	0.093	-1.380	FBXL4	F-box and leucine-rich repeat protein 4	6	-99428321	AW770868	26235	6q16.1-q16.3	Hs.536850	6	ubiquitin ligase complex nucleus cytoplasm ubiquitin-dependent protein catabolic process
210379_s_at	-0.381	3.849	-3.646	2.339e-03	0.093	-1.381	TLK1	tousled-like kinase 1	2	-171555578, -171555578, -171555578	AF162666	9874	2q31.1	Hs.719163	23	nucleotide binding regulation of chromatin assembly or disassembly protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus protein amino acid phosphorylation intracellular protein transport response to DNA damage stimulus cell cycle intracellular signaling cascade chromatin modification transferase activity
1569906_s_at	-0.387	6.371	-3.645	2.344e-03	0.093	-1.383	PHF20	PHD finger protein 20	20	33823336	BC015538	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225885_at	-0.641	8.605	-3.645	2.344e-03	0.093	-1.383	EEA1	early endosome antigen 1	12	-91690415	AI336848	8411	12q22	Hs.567367	32	calmodulin binding phosphatidylinositol binding intracellular membrane fraction cytoplasm early endosome cytosol serine-pyruvate aminotransferase complex vesicle fusion zinc ion binding membrane synaptic vesicle to endosome fusion extrinsic to plasma membrane GTP-dependent protein binding protein homodimerization activity early endosome to late endosome transport metal ion binding	Endocytosis
225662_at	-0.449	11.537	-3.644	2.349e-03	0.093	-1.385	ZAK	sterile alpha motif and leucine zipper containing kinase AZK	2	173648810, 173648810	H28667	51776	2q24.2	Hs.444451	24	cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis	MAPK signaling pathway Tight junction
218237_s_at	2.306	7.326	3.643	2.356e-03	0.093	-1.388	SLC38A1	solute carrier family 38, member 1	12	-44863107	NM_030674	81539	12q13.11	Hs.694701	11	sodium:amino acid symporter activity membrane fraction plasma membrane ion transport sodium ion transport glutamine transport L-glutamine transmembrane transporter activity symporter activity integral to membrane axon sodium ion binding
1569566_at	-0.957	4.803	-3.643	2.357e-03	0.093	-1.388	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	BC028196	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
200912_s_at	-0.351	12.291	-3.642	2.361e-03	0.093	-1.389	EIF4A2	eukaryotic translation initiation factor 4A, isoform 2	3	187984054	NM_001967	1974	3q28	Hs.518475 Hs.599481	15	nucleotide binding RNA binding translation initiation factor activity helicase activity protein binding ATP binding cytosol translation regulation of translational initiation ATP-dependent helicase activity eukaryotic translation initiation factor 4F complex hydrolase activity interspecies interaction between organisms
232488_at	0.518	6.953	3.642	2.362e-03	0.093	-1.390	AGXT2L2	alanine-glyoxylate aminotransferase 2-like 2	5	-177568146	AK023470	85007	5q35.3	Hs.248746	4	mitochondrion transaminase activity transferase activity pyridoxal phosphate binding
210210_at	0.289	6.120	3.641	2.366e-03	0.093	-1.391	MPZL1	myelin protein zero-like 1	1	165957810	AF181660	9019	1q24.2	Hs.493919 Hs.603116	19	structural molecule activity protein binding integral to plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling membrane	Cell adhesion molecules (CAMs)
210283_x_at	-0.520	9.023	-3.641	2.367e-03	0.093	-1.392	PAIP1	poly(A) binding protein interacting protein 1	5	-43562126, -43562126	BC005295	10605	5p12	Hs.482038	12	RNA binding protein binding cytoplasm translational initiation regulation of translation translation activator activity RNA metabolic process mRNA stabilization
203421_at	0.364	6.662	3.640	2.369e-03	0.093	-1.393	TP53I11	tumor protein p53 inducible protein 11	11	-44910474	NM_006034	9537	11p11.2	Hs.554791	10	response to stress negative regulation of cell proliferation
204720_s_at	0.967	3.220	3.640	2.371e-03	0.093	-1.393	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6	1	65503017	AV729634	9829	1pter-q31.3	Hs.647643	11	protein tyrosine phosphatase activity hydrolase activity SH3 domain binding heat shock protein binding	Endocytosis
217833_at	-0.650	8.199	-3.640	2.371e-03	0.093	-1.394	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	AL520908	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
225332_at	-0.527	9.043	-3.639	2.375e-03	0.093	-1.395	LOC729082	hypothetical protein LOC729082	15	39363492	BF674064	729082	15q15.1	Hs.380164	2
202537_s_at	-0.359	7.534	-3.638	2.379e-03	0.093	-1.396	CHMP2B	chromatin modifying protein 2B	3	87359102	AF151842	25978	3p11.2	Hs.476930	36	intracellular cytoplasm endosome cytosol protein transport membrane protein domain specific binding	Endocytosis
202334_s_at	-0.722	10.002	-3.637	2.383e-03	0.093	-1.398	UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	5	133734768	AI768723	7320	5q23-q31	Hs.615284 Hs.644421	23	nucleotide binding protein polyubiquitination chromatin ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus replication fork cytoplasm plasma membrane postreplication repair postreplication repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein monoubiquitination response to DNA damage stimulus spermatogenesis sperm axoneme assembly response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination response to drug protein stabilization regulation of protein metabolic process protein autoubiquitination Wnt receptor signaling pathway through beta-catenin	Ubiquitin mediated proteolysis
203310_at	-0.704	7.350	-3.637	2.384e-03	0.093	-1.398	STXBP3	syntaxin binding protein 3	1	109090807	NM_007269	6814	1p13.3	Hs.530436	14	molecular_function cellular_component cytoplasm cytosol cytosol plasma membrane vesicle docking during exocytosis biological_process protein transport vesicle-mediated transport
210115_at	0.528	4.086	3.637	2.386e-03	0.093	-1.399	RPL39L	ribosomal protein L39-like	3	-188321434	L05096	116832	3q27	Hs.647900	4	structural constituent of ribosome intracellular ribosome translation spermatogenesis cytosolic large ribosomal subunit
218264_at	-0.319	7.406	-3.637	2.387e-03	0.093	-1.399	BCCIP	BRCA2 and CDKN1A interacting protein	10	127502093, 127502093, 127502093	NM_016567	56647	10q26.1	Hs.370292 Hs.715543	31	regulation of cyclin-dependent protein kinase activity protein binding nucleus DNA repair response to DNA damage stimulus cell cycle
223904_at	-0.975	6.778	-3.634	2.400e-03	0.093	-1.405	PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	2	-219395349	AF214519	53632	2q35	Hs.591634	13	AMP-activated protein kinase activity glycogen biosynthetic process fatty acid biosynthetic process protein kinase cascade glucose transport protein kinase binding	Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
215676_at	0.341	5.614	3.633	2.406e-03	0.093	-1.407	BRF1	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)	14	-104746669, -104746667	N91109	2972	14q	Hs.424484	27	transcription factor TFIIIB complex transcription factor activity RNA polymerase III transcription factor activity translation initiation factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription initiation from RNA polymerase III promoter translational initiation zinc ion binding rRNA transcription tRNA transcription transcription activator activity positive regulation of transcription metal ion binding
205087_at	-0.626	7.033	-3.633	2.407e-03	0.093	-1.407	RWDD3	RWD domain containing 3	1	95472298	NM_015485	25950	1p21.3	Hs.709591	11	protein binding nucleus cytoplasm
222580_at	-0.589	7.613	-3.631	2.413e-03	0.094	-1.410	ZNF644	zinc finger protein 644	1	-91153444, -91153444	AK023596	84146	1p22.2	Hs.173001	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
213251_at	-0.476	7.781	-3.631	2.415e-03	0.094	-1.411	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	AV712064	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
214640_at	-0.308	2.713	-3.629	2.424e-03	0.094	-1.414	UNC93A	unc-93 homolog A (C. elegans)	6	167624792	AL021331	54346	6q27	Hs.567508	4	molecular_function plasma membrane biological_process integral to membrane
230331_at	-0.811	4.051	-3.629	2.425e-03	0.094	-1.414	C13orf39	chromosome 13 open reading frame 39	13	-102136097	AI333373	196541	13q33.1	Hs.508623	1
202447_at	0.576	10.373	3.628	2.429e-03	0.094	-1.416	DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	8	91082755	NM_001359	1666	8q21.3	Hs.492212	22	binding mitochondrion fatty acid beta-oxidation fatty acid beta-oxidation 2,4-dienoyl-CoA reductase (NADPH) activity 2,4-dienoyl-CoA reductase (NADPH) activity oxidoreductase activity protein homotetramerization oxidation reduction NADPH binding
206492_at	0.708	5.547	3.628	2.431e-03	0.094	-1.417	FHIT	fragile histidine triad gene	3	-59710075	NM_002012	2272	3p14.2	Hs.715588 Hs.715597	164	magnesium ion binding protein binding cytoplasm DNA replication nucleotide metabolic process hydrolase activity manganese ion binding bis(5'-adenosyl)-triphosphatase activity	Purine metabolism Small cell lung cancer Non-small cell lung cancer
208884_s_at	-0.526	7.241	-3.627	2.433e-03	0.094	-1.417	UBR5	ubiquitin protein ligase E3 component n-recognin 5	8	-103334744	AF006010	51366	8q22	Hs.591856	21	RNA binding ubiquitin-protein ligase activity protein binding intracellular soluble fraction nucleus protein modification process ubiquitin-dependent protein catabolic process response to DNA damage stimulus zinc ion binding cell proliferation ligase activity acid-amino acid ligase activity metal ion binding progesterone receptor signaling pathway	Ubiquitin mediated proteolysis
209236_at	0.340	5.495	3.626	2.437e-03	0.094	-1.419	SLC23A2	solute carrier family 23 (nucleobase transporters), member 2	20	-4781001, -4781001	AL389886	9962	20p13	Hs.516866	34	transporter activity membrane fraction integral to plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ion transport sodium ion transport sodium-dependent multivitamin transmembrane transporter activity nucleobase transmembrane transporter activity symporter activity nucleobase transport molecular hydrogen transport membrane L-ascorbic acid metabolic process sodium ion binding
229820_at	0.564	5.322	3.626	2.438e-03	0.094	-1.419	LOC440993	hypothetical LOC440993	3		BF509179	440993	3q29	Hs.709411
209696_at	0.363	4.851	3.626	2.438e-03	0.094	-1.419	FBP1	fructose-1,6-bisphosphatase 1	9	-96405237, -96405237	D26054	2203	9q22.3	Hs.494496	31	magnesium ion binding fructose-2,6-bisphosphate 2-phosphatase activity cytosol carbohydrate metabolic process fructose metabolic process gluconeogenesis hydrolase activity fructose 1,6-bisphosphate 1-phosphatase activity fructose 1,6-bisphosphate 1-phosphatase activity phosphoric ester hydrolase activity identical protein binding	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Metabolic pathways Insulin signaling pathway
1558388_a_at	0.612	2.892	3.626	2.438e-03	0.094	-1.419	LOC643763	hypothetical LOC643763	8	64052973	R41806	643763	8q12.3	Hs.491856	2
226617_at	-0.670	8.348	-3.626	2.439e-03	0.094	-1.420	ARL5A	ADP-ribosylation factor-like 5A	2	-152365725	AW291264	26225	2q23.3	Hs.470233	6	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
208615_s_at	-0.645	9.549	-3.625	2.444e-03	0.094	-1.421	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	BF795101	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
206580_s_at	0.444	6.882	3.623	2.454e-03	0.094	-1.425	EFEMP2	EGF-containing fibulin-like extracellular matrix protein 2	11	-65390487	NM_016938	30008	11q13.1	Hs.170622	15	transmembrane receptor activity extracellular matrix structural constituent calcium ion binding protein binding extracellular region basement membrane blood coagulation membrane
225805_at	-0.598	5.331	-3.623	2.455e-03	0.094	-1.426	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	AW137669	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
208894_at	1.143	8.453	3.623	2.456e-03	0.094	-1.426	HLA-DRA	major histocompatibility complex, class II, DR alpha	6	32515624, 3814608, 3622461	M60334	3122	6p21.3	Hs.520048	134	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II lysosome plasma membrane plasma membrane integral to plasma membrane immune response MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
210658_s_at	-0.397	5.965	-3.622	2.459e-03	0.094	-1.427	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	16	-23383143	BC000284	23062	16p12	Hs.460336	37	protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding	Lysosome
201604_s_at	-0.455	6.274	-3.622	2.462e-03	0.094	-1.428	PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	12	-78691474, -78691474, -78691474	NM_002480	4659	12q15-q21	Hs.49582	41	signal transducer activity protein binding cytoplasm	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton
211725_s_at	1.042	4.851	3.621	2.464e-03	0.094	-1.429	BID	BH3 interacting domain death agonist	22	-16596905, -16596905	BC005884	637	22q11.1	Hs.591054	111	release of cytochrome c from mitochondria death receptor binding protein binding membrane fraction cytoplasm mitochondrion mitochondrial outer membrane cytosol cytosol induction of apoptosis via death domain receptors activation of pro-apoptotic gene products membrane regulation of mitochondrial membrane permeability neuron apoptosis	p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer
231930_at	-0.756	4.562	-3.621	2.467e-03	0.094	-1.430	ELMOD1	ELMO/CED-12 domain containing 1	11	106967026	AL359601	55531	11q22.3	Hs.495779	5	cytoskeleton phagocytosis
230821_at	-0.445	5.839	-3.621	2.467e-03	0.094	-1.430	ZNF148	zinc finger protein 148	3	-126427202	AW594167	7707	3q21	Hs.592591	34	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex nucleolus Golgi apparatus cellular defense response gamete generation zinc ion binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
210386_s_at	0.304	6.834	3.620	2.471e-03	0.094	-1.432	MTX1	metaxin 1	1	153445113, 153445113	BC001906	4580	1q21	Hs.490874	13	protein binding mitochondrion mitochondrial outer membrane mitochondrial inner membrane protein targeting to mitochondrion protein transport membrane integral to membrane
209047_at	0.546	8.788	3.619	2.475e-03	0.094	-1.433	AQP1	aquaporin 1 (Colton blood group)	7	30917992	AL518391	358	7p14	Hs.76152	100	transporter activity protein binding integral to plasma membrane transport water transport excretion water channel activity carbon dioxide transport ammonium transport membrane basolateral plasma membrane apical plasma membrane ammonia transporter activity
240770_at	0.781	2.734	3.618	2.479e-03	0.094	-1.435	TMEM171	transmembrane protein 171	5	72452143	AW058459	134285	5q13.2	Hs.162246	5	membrane integral to membrane
1553357_at	-0.597	3.153	-3.617	2.487e-03	0.094	-1.438	LOC158696	hypothetical LOC158696	X	-137524557	NM_153016	158696	Xq26.3	Hs.558664	3
204279_at	0.567	6.795	3.616	2.490e-03	0.094	-1.439	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	6	32929915, 4202792, 4007991	NM_002800	5698	6p21.3	Hs.654585	72	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex immune response peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
225801_at	-1.355	5.913	-3.616	2.490e-03	0.094	-1.439	FBXO32	F-box protein 32	8	-124584538, -124584538	AW518714	114907	8q24.13	Hs.403933	17	protein binding modification-dependent protein catabolic process
239839_at	0.447	4.127	3.616	2.493e-03	0.094	-1.440	ZNF555	zinc finger protein 555	19	2792481	BF435923	148254	19p13.3	Hs.47712	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212760_at	-0.506	8.644	-3.613	2.504e-03	0.095	-1.444	UBR2	ubiquitin protein ligase E3 component n-recognin 2	6	42640035	AB002347	23304	6p21.1	Hs.529925	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus ubiquitin-dependent protein catabolic process male meiosis I spermatogenesis zinc ion binding ligase activity protein catabolic process metal ion binding
202566_s_at	-0.706	9.802	-3.613	2.506e-03	0.095	-1.445	SVIL	supervillin	10	-29786282, -29786282	AF051851	6840	10p11.2	Hs.499209	23	podosome calcium ion binding nucleus cytoplasm plasma membrane cytoskeleton organization skeletal muscle tissue development cell projection costamere actin filament binding
214334_x_at	-0.392	9.875	-3.611	2.516e-03	0.095	-1.448	DAZAP2	DAZ associated protein 2	12	49918774, 49918774	N34846	9802	12q12	Hs.369761	15	protein binding WW domain binding
204683_at	0.435	6.987	3.609	2.528e-03	0.095	-1.453	ICAM2	intercellular adhesion molecule 2	17	-59433686, -59433686	NM_000873	3384	17q23-q25	Hs.431460	45	uropod integrin binding protein binding plasma membrane plasma membrane integral to plasma membrane cell-cell adhesion	Cell adhesion molecules (CAMs) Natural killer cell mediated cytotoxicity
227767_at	-0.464	5.679	-3.608	2.531e-03	0.095	-1.454	CSNK1G3	casein kinase 1, gamma 3	5	122875691	AI073822	1456	5q23	Hs.129206	6	nucleotide binding protein serine/threonine kinase activity ATP binding cytoplasm protein modification process protein amino acid phosphorylation signal transduction Wnt receptor signaling pathway transferase activity	Hedgehog signaling pathway
217868_s_at	-0.307	8.863	-3.607	2.536e-03	0.095	-1.456	METTL9	methyltransferase like 9	16	21518356	NM_016025	51108	16p13-p12	Hs.279583	6
209422_at	-0.741	7.978	-3.607	2.537e-03	0.095	-1.456	PHF20	PHD finger protein 20	20	33823336	AL109965	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
213891_s_at	0.419	8.860	3.607	2.537e-03	0.095	-1.456	TCF4	transcription factor 4	18	-51040559	AI927067	6925	18q21.1	Hs.605153	55	transcription factor activity protein binding nucleus regulation of transcription positive regulation of transcription, DNA-dependent protein heterodimerization activity
228185_at	-0.520	7.338	-3.607	2.538e-03	0.095	-1.457	ZNF25	zinc finger protein 25	10	-38278800	N32599	219749	10p11.1	Hs.499429	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212468_at	-0.613	6.974	-3.605	2.548e-03	0.095	-1.460	SPAG9	sperm associated antigen 9	17	-46394534	AK023512	9043	17q21.33	Hs.463439	22	acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm
201501_s_at	-0.513	8.926	-3.605	2.550e-03	0.095	-1.461	GRSF1	G-rich RNA sequence binding factor 1	4	-71900362, -71900362	NM_002092	2926	4q13	Hs.309763	6	mRNA binding cytoplasm mRNA polyadenylation
200731_s_at	-0.653	9.773	-3.604	2.551e-03	0.095	-1.461	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	AW165960	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
225329_at	0.294	6.748	3.604	2.553e-03	0.095	-1.462	LOC348262	hypothetical protein LOC348262	17	-2338651	BF338291	348262	17q25.3	Hs.514632	1
217593_at	0.396	6.065	3.604	2.554e-03	0.095	-1.462	ZSCAN18	zinc finger and SCAN domain containing 18	19	-63310783, -63287021, -63287021	AI375002	65982	19q13.43	Hs.235390	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212435_at	-0.384	7.497	-3.603	2.560e-03	0.095	-1.465	TRIM33	tripartite motif-containing 33	1	-114736921	AA205593	51592	1p13.1	Hs.26837	12	DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding
1555812_a_at	0.551	6.031	3.602	2.562e-03	0.095	-1.465	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	12	-14986216	AF498927	397	12p12.3	Hs.504877	34	Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding cytoplasm cytoskeleton cell motion immune response negative regulation of cell adhesion Rho protein signal transduction multicellular organismal development cytoplasmic membrane-bounded vesicle actin cytoskeleton organization	Neurotrophin signaling pathway
200710_at	0.518	11.429	3.600	2.577e-03	0.096	-1.471	ACADVL	acyl-Coenzyme A dehydrogenase, very long chain	17	7063876	NM_000018	37	17p13-p11	Hs.437178 Hs.463928	30	long-chain-acyl-CoA dehydrogenase activity mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation electron carrier activity energy derivation by oxidation of organic compounds membrane mitochondrial nucleoid FAD binding oxidation reduction	Fatty acid metabolism Metabolic pathways
227584_at	0.365	6.289	3.599	2.578e-03	0.096	-1.471	NAV1	neuron navigator 1	1	199884072	BF339566	89796	1q32.3	Hs.585374	10	nucleotide binding cytoplasm cytoskeleton microtubule multicellular organismal development nervous system development nucleoside-triphosphatase activity cell differentiation
1557720_s_at	1.077	4.018	3.598	2.586e-03	0.096	-1.474	MYO16	myosin XVI	13	108046500	BC041343	23026	13q33.3	Hs.656587	7	nucleotide binding motor activity ATP binding nucleoplasm cytoplasm plasma membrane negative regulation of cell proliferation myosin complex cerebellum development negative regulation of S phase of mitotic cell cycle perinuclear region of cytoplasm actin filament binding
203192_at	-0.484	6.466	-3.597	2.591e-03	0.096	-1.476	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6	2	-219782737	NM_005689	10058	2q36	Hs.107911	15	nucleotide binding ATP binding mitochondrion mitochondrial envelope mitochondrial outer membrane transport cellular iron ion homeostasis membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters
1553993_s_at	-0.713	7.766	-3.596	2.593e-03	0.096	-1.477	MED25	mediator complex subunit 25	19	55013357	BC024312	81857	19q13.3	Hs.656639	13	nucleus regulation of transcription
205091_x_at	-0.558	5.452	-3.596	2.593e-03	0.096	-1.477	RECQL	RecQ protein-like (DNA helicase Q1-like)	12	-21513111	NM_002907	5965	12p12	Hs.235069	29	nucleotide binding DNA strand renaturation DNA strand annealing activity DNA binding ATP-dependent DNA helicase activity protein binding ATP binding nucleus DNA repair DNA recombination hydrolase activity
214121_x_at	-0.660	9.173	-3.596	2.597e-03	0.096	-1.478	PDLIM7	PDZ and LIM domain 7 (enigma)	5	-176849852, -176843000	AA086229	9260	5q35.3	Hs.533040	22	ossification protein binding cytoplasm cytoskeleton receptor-mediated endocytosis multicellular organismal development zinc ion binding cell differentiation metal ion binding
202546_at	0.697	6.278	3.595	2.599e-03	0.096	-1.478	VAMP8	vesicle-associated membrane protein 8 (endobrevin)	2	85658158	NM_003761	8673	2p12-p11.2	Hs.714302	27	protein binding membrane fraction early endosome membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
228153_at	-0.534	9.778	-3.595	2.602e-03	0.096	-1.480	RNF144B	ring finger protein 144B	6	18495572	AI953847	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
228624_at	0.363	4.156	3.594	2.604e-03	0.096	-1.480	TMEM144	transmembrane protein 144	4	159350850	AI432488	55314	4q32.1	Hs.718582	2	membrane integral to membrane
214468_at	1.361	8.940	3.594	2.606e-03	0.096	-1.481	MYH6	myosin, heavy chain 6, cardiac muscle, alpha	14	-22921038	D00943	4624	14q12	Hs.278432	23	microfilament motor activity nucleotide binding in utero embryonic development regulation of the force of heart contraction regulation of heart rate actin binding calmodulin binding ATP binding nucleus nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction adult heart development visceral muscle development regulation of blood pressure structural constituent of muscle myosin complex ATPase activity actin filament-based movement muscle filament sliding actin-dependent ATPase activity regulation of ATPase activity sarcomere organization cardiac muscle fiber development atrial cardiac muscle morphogenesis ventricular cardiac muscle morphogenesis	Cardiac muscle contraction Tight junction Hypertrophic cardiomyopathy (HCM)
1565329_at	0.527	2.450	3.594	2.608e-03	0.096	-1.482	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)	2	75039282	AY034104	56655	2p12	Hs.469060	5	DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
224690_at	0.787	9.832	3.593	2.613e-03	0.096	-1.484	C20orf108	chromosome 20 open reading frame 108	20	54367389	BG432350	116151	20q13.2	Hs.143736 Hs.593629	6	membrane integral to membrane
200737_at	-0.803	8.965	-3.592	2.619e-03	0.096	-1.486	PGK1	phosphoglycerate kinase 1	X	77246321	NM_000291	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
201133_s_at	-0.536	8.032	-3.591	2.620e-03	0.096	-1.486	PJA2	praja ring finger 2	5	-108698308	AA142966	9867	5q21.3	Hs.483036 Hs.592564	10	protein binding cytoplasm endoplasmic reticulum Golgi apparatus plasma membrane zinc ion binding postsynaptic density ligase activity modification-dependent protein catabolic process cell junction synapse postsynaptic membrane metal ion binding
205047_s_at	2.648	6.156	3.591	2.622e-03	0.096	-1.487	ASNS	asparagine synthetase	7	-97319376, -97319376	NM_001673	440	7q21.3	Hs.489207	36	nucleotide binding asparagine synthase (glutamine-hydrolyzing) activity asparagine synthase (glutamine-hydrolyzing) activity ATP binding soluble fraction cytosol asparagine biosynthetic process glutamine metabolic process metabolic process cellular amino acid biosynthetic process ligase activity cellular response to glucose starvation negative regulation of apoptosis positive regulation of mitotic cell cycle	Alanine, aspartate and glutamate metabolism Nitrogen metabolism Metabolic pathways
208729_x_at	0.560	9.421	3.590	2.627e-03	0.097	-1.489	HLA-B	major histocompatibility complex, class I, B	6	-31429627, -2770844, -2569111	D83043	3106	6p21.3	Hs.707171 Hs.77961	1101	antigen processing and presentation of peptide antigen via MHC class I protein binding membrane fraction plasma membrane integral to plasma membrane defense response immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
202902_s_at	0.454	5.824	3.589	2.633e-03	0.097	-1.491	CTSS	cathepsin S	1	-148969175	NM_004079	1520	1q21	Hs.181301	62	cysteine-type endopeptidase activity extracellular region lysosome proteolysis immune response peptidase activity membrane intracellular membrane-bounded organelle	Lysosome Antigen processing and presentation
201360_at	0.647	8.529	3.588	2.638e-03	0.097	-1.492	CST3	cystatin C	20	-23562293	NM_000099	1471	20p11.21	Hs.304682	151	beta-amyloid binding protease binding cysteine-type endopeptidase inhibitor activity extracellular region extracellular space defense response negative regulation of peptidase activity negative regulation of histolysis negative regulation of collagen catabolic process negative regulation of extracellular matrix disassembly peptidase inhibitor activity regulation of tissue remodeling fibril organization negative regulation of elastin catabolic process negative regulation of blood vessel remodeling
219643_at	-2.114	5.193	-3.586	2.649e-03	0.097	-1.496	LRP1B	low density lipoprotein-related protein 1B (deleted in tumors)	2	-140705465	NM_018557	53353	2q21.2	Hs.656461	14	receptor activity low-density lipoprotein receptor activity calcium ion binding protein binding membrane fraction receptor-mediated endocytosis protein transport membrane integral to membrane
229253_at	-0.425	6.881	-3.586	2.652e-03	0.097	-1.497	THEM4	thioesterase superfamily member 4	1	-150112683	AI184512	117145	1q21	Hs.164070	8	cytoplasm plasma membrane ruffle membrane cell projection
219418_at	-0.391	6.396	-3.585	2.652e-03	0.097	-1.498	NHEJ1	nonhomologous end-joining factor 1	2	-219648289	NM_024782	79840	2q35	Hs.225988	27	DNA binding nucleus DNA repair double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development response to ionizing radiation B cell differentiation T cell differentiation identical protein binding positive regulation of ligase activity	Non-homologous end-joining
241710_at	0.532	3.914	3.585	2.655e-03	0.097	-1.498	hCG_1645220	hCG1645220	2	-43755795	AI436290	728819	2p21	Hs.602756	1
227268_at	-0.892	6.024	-3.584	2.662e-03	0.097	-1.501	RNFT1	ring finger protein, transmembrane 1	17	-55384504	N51514	51136	17q23.1	Hs.531701	1	protein binding zinc ion binding membrane integral to membrane metal ion binding
231948_s_at	-0.427	7.718	-3.583	2.664e-03	0.097	-1.501	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	2	238540438	BG171548	140739	2q37.3	Hs.471785	4	nucleotide binding protein binding ATP binding ligase activity NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation regulation of protein metabolic process	Ubiquitin mediated proteolysis
211961_s_at	-0.534	9.232	-3.583	2.666e-03	0.097	-1.502	RAB7A	RAB7A, member RAS oncogene family	3	129927668	AK000826	7879	3q21.3	Hs.15738 Hs.716392	64	nucleotide binding GTPase activity protein binding GTP binding cytoplasm lysosome late endosome Golgi apparatus endocytosis small GTPase mediated signal transduction protein transport cytoplasmic vesicle melanosome phagocytic vesicle
218023_s_at	-0.532	8.354	-3.583	2.669e-03	0.097	-1.503	FAM53C	family with sequence similarity 53, member C	5	137701122, 137701602	NM_016605	51307	5q31	Hs.716415	7
222447_at	-0.534	7.726	-3.582	2.669e-03	0.097	-1.503	METTL9	methyltransferase like 9	16	21518356	BC000195	51108	16p13-p12	Hs.279583	6
1569029_at	0.398	3.286	3.582	2.671e-03	0.097	-1.504	MAP1D	methionine aminopeptidase 1D	2	172573049	AA442226	254042	2q31.1	Hs.298250	4	aminopeptidase activity mitochondrion proteolysis peptidase activity metalloexopeptidase activity cellular process peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding
211721_s_at	0.383	3.175	3.582	2.672e-03	0.097	-1.504	ZNF551	zinc finger protein 551	19	62885168	BC005868	90233	19q13.43	Hs.109540	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229337_at	-0.557	7.584	-3.581	2.675e-03	0.097	-1.505	USP2	ubiquitin specific peptidase 2	11	-118731134, -118731134	AW274034	9099	11q23.3	Hs.524085	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm plasma membrane ubiquitin-dependent protein catabolic process peptidase activity
214186_s_at	0.324	6.647	3.581	2.676e-03	0.097	-1.506	HCG26	HLA complex group 26 (non-protein coding)	6	31546984, 2885166	AI346483	352961	6p21.3	Hs.132807	3
237447_at	0.450	5.134	3.581	2.677e-03	0.097	-1.506	C22orf45	chromosome 22 open reading frame 45	22		BF509218	646023	22q11.23	Hs.712771	2
222921_s_at	-0.420	6.677	-3.581	2.678e-03	0.097	-1.506	HEY2	hairy/enhancer-of-split related with YRPW motif 2	6	126112424	AF232238	23493	6q21	Hs.144287	23	transcription factor activity nucleus regulation of transcription, DNA-dependent Notch signaling pathway multicellular organismal development nervous system development organ morphogenesis
207284_s_at	-0.571	6.962	-3.581	2.678e-03	0.097	-1.506	ASPH	aspartate beta-hydroxylase	8	-62739837, -62699648, -62699648, -62575669	NM_020164	444	8q12.1	Hs.591874	24	peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis
228461_at	0.494	6.567	3.581	2.680e-03	0.097	-1.507	SH3RF3	SH3 domain containing ring finger 3	2	109112428	AL566989	344558	2q13	Hs.171244 Hs.535157	2	protein binding zinc ion binding metal ion binding
206833_s_at	-0.570	10.363	-3.580	2.683e-03	0.097	-1.508	ACYP2	acylphosphatase 2, muscle type	2	54195913	NM_001108	98	2p16.2	Hs.516173 Hs.642983	16	acylphosphatase activity phosphate metabolic process hydrolase activity	Pyruvate metabolism Benzoate degradation via CoA ligation
222125_s_at	0.341	6.465	3.580	2.683e-03	0.097	-1.508	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	3	49002344	BC000580	54681	3p21.31	Hs.654944	9	iron ion binding calcium ion binding endoplasmic reticulum membrane integral to membrane oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding oxidation reduction
232173_at	0.403	5.724	3.578	2.693e-03	0.097	-1.512	CLEC2L	C-type lectin domain family 2, member L	7	138859213	W60866	154790	7q34	Hs.57806	3	binding sugar binding membrane integral to membrane
230264_s_at	-0.547	9.723	-3.578	2.696e-03	0.097	-1.513	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	X	-15753849	AA551090	8905	Xp22.2	Hs.653504 Hs.656471	21	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
210389_x_at	-0.502	5.765	-3.578	2.696e-03	0.097	-1.513	TUBD1	tubulin, delta 1	17	-55291632	BC000258	51174	17q23.1	Hs.463638	7	nucleotide binding GTPase activity structural molecule activity GTP binding nucleus cytoplasm centriole microtubule microtubule-based movement multicellular organismal development spermatogenesis cell differentiation protein complex protein polymerization
243309_at	-0.643	5.284	-3.577	2.698e-03	0.097	-1.514	FLJ27352	hypothetical LOC145788	15		AA398658	145788	15q21.3	Hs.97300
1555982_at	-0.253	2.406	-3.577	2.699e-03	0.097	-1.514	ZFYVE16	zinc finger, FYVE domain containing 16	5	79739593	BU078629	9765	5q14	Hs.482660 Hs.660410	15	protein binding phosphatidylinositol binding cytoplasm protein targeting to lysosome signal transduction zinc ion binding protein transporter activity membrane vesicle organization endosome transport regulation of endocytosis BMP signaling pathway early endosome membrane metal ion binding	TGF-beta signaling pathway
223229_at	-0.569	6.718	-3.577	2.701e-03	0.097	-1.514	UBE2T	ubiquitin-conjugating enzyme E2T (putative)	1	-200567408	AB032931	29089	1q32.1	Hs.5199	10	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
222550_at	-0.353	8.687	-3.576	2.705e-03	0.097	-1.516	ARMC1	armadillo repeat containing 1	8	-66677627	AK024053	55156	8q13.1	Hs.269542	3	binding metal ion transport metal ion binding
208946_s_at	-0.531	8.279	-3.575	2.711e-03	0.098	-1.518	BECN1	beclin 1, autophagy related	17	-38215675	AF139131	8678	17q21	Hs.716464	56	protein binding cytoplasm Golgi apparatus trans-Golgi network autophagy anti-apoptosis cellular defense response negative regulation of cell proliferation response to virus membrane cytoplasmic membrane-bounded vesicle positive regulation of macroautophagy protein complex	Regulation of autophagy
232244_at	-0.963	6.557	-3.575	2.712e-03	0.098	-1.518	KIAA1161	KIAA1161	9	-34358906	AB032987	57462	9p13.3	Hs.522083	3	hydrolase activity, hydrolyzing O-glycosyl compounds carbohydrate metabolic process metabolic process membrane integral to membrane
211576_s_at	0.321	5.703	3.574	2.716e-03	0.098	-1.520	SLC19A1	solute carrier family 19 (folate transporter), member 1	21	-45759056	BC003068	6573	21q22.3	Hs.84190	93	folic acid binding membrane fraction integral to plasma membrane transport folic acid transporter activity reduced folate carrier activity methotrexate transporter activity folic acid transport membrane
225915_at	-1.068	5.996	-3.573	2.721e-03	0.098	-1.521	CAB39L	calcium binding protein 39-like	13	-48780786, -48780786	AL138875	81617	13q14.2	Hs.87159	9	protein binding	mTOR signaling pathway
227084_at	-1.271	8.938	-3.572	2.727e-03	0.098	-1.523	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	AW339310	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
208204_s_at	-0.762	9.284	-3.570	2.737e-03	0.098	-1.527	CAV3	caveolin 3	3	8750495	NM_001234	859	3p25	Hs.98303	73	membrane fraction Golgi apparatus caveola triglyceride metabolic process elevation of cytosolic calcium ion concentration muscle organ development protein C-terminus binding protein localization negative regulation of cardiac muscle hypertrophy regulation of skeletal muscle contraction dystrophin-associated glycoprotein complex integral to membrane cell growth sodium channel regulator activity Z disc cell differentiation T-tubule positive regulation of microtubule polymerization membrane raft organization neuromuscular junction protein complex binding protein complex scaffold T-tubule organization regulation of membrane potential glucose homeostasis cholesterol homeostasis negative regulation of MAP kinase activity negative regulation of MAPKKK cascade negative regulation of cell size muscle maintenance negative regulation of nitric-oxide synthase activity regulation of calcium ion transport via voltage-gated calcium channel activity negative regulation of sarcomere organization regulation of ventricular cardiomyocyte membrane repolarization	Focal adhesion
225273_at	0.487	6.123	3.570	2.737e-03	0.098	-1.527	WWC3	WWC family member 3	X	9943794	AB033106	55841	Xp22.32	Hs.527524	5
218553_s_at	0.394	5.395	3.569	2.743e-03	0.098	-1.529	KCTD15	potassium channel tetramerisation domain containing 15	19	38979590	NM_024076	79047	19q13.11	Hs.221873 Hs.606506	12	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
228718_at	0.486	5.727	3.568	2.748e-03	0.098	-1.530	ZNF44	zinc finger protein 44	19	-12243624	AI379070	51710	19p13.2	Hs.296731 Hs.693933	10	DNA binding protein binding intracellular nucleus cytoplasm cytoskeleton regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1566134_at	0.359	6.179	3.566	2.761e-03	0.099	-1.535	CARHSP1	calcium regulated heat stable protein 1, 24kDa	16	-8854302, -8854302	AL832316	23589	16p13.2	Hs.632184	13	DNA binding protein binding cytoplasm regulation of transcription, DNA-dependent intracellular signaling cascade phosphatase binding
201905_s_at	0.582	5.396	3.565	2.769e-03	0.099	-1.538	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF590317	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
223716_s_at	-0.356	9.448	-3.564	2.772e-03	0.099	-1.538	ZRANB2	zinc finger, RAN-binding domain containing 2	1	-71301561	AF065391	9406	1p31	Hs.194718	18	transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding
213552_at	0.461	4.640	3.563	2.776e-03	0.099	-1.540	GLCE	glucuronic acid epimerase	15	67240026	W87398	26035	15q23	Hs.183006	9	Golgi apparatus heparan sulfate proteoglycan biosynthetic process membrane integral to membrane isomerase activity heparin biosynthetic process UDP-glucuronate 5'-epimerase activity	Heparan sulfate biosynthesis Metabolic pathways
223126_s_at	-0.521	7.260	-3.563	2.778e-03	0.099	-1.541	C1orf21	chromosome 1 open reading frame 21	1	182622772	AI159874	81563	1q25	Hs.497159 Hs.719188	8
224772_at	0.363	6.163	3.562	2.782e-03	0.099	-1.542	NAV1	neuron navigator 1	1	199884072	AB032977	89796	1q32.3	Hs.585374	10	nucleotide binding cytoplasm cytoskeleton microtubule multicellular organismal development nervous system development nucleoside-triphosphatase activity cell differentiation
238843_at	-0.533	6.833	-3.561	2.788e-03	0.099	-1.544	NPHP1	nephronophthisis 1 (juvenile)	2	-110238202	BF216535	4867	2q13	Hs.280388	36	structural molecule activity protein binding adherens junction signal transduction excretion visual behavior membrane cell-cell adhesion actin cytoskeleton organization cell junction
229618_at	-0.418	5.703	-3.560	2.798e-03	0.099	-1.547	SNX16	sorting nexin 16	8	-82874372	AW150236	64089	8q21.13	Hs.492121	7	protein binding cell communication protein transport phosphoinositide binding
225157_at	-0.589	9.347	-3.559	2.800e-03	0.099	-1.548	MLXIP	MLX interacting protein	12	121001142	AW245631	22877	12q24.31	Hs.437153	7	DNA binding nucleus cytoplasm mitochondrion mitochondrial outer membrane membrane transcription regulator activity regulation of transcription
230090_at	-1.569	5.755	-3.559	2.801e-03	0.099	-1.548	GDNF	glial cell derived neurotrophic factor	5	-37851509, -37851509, -37851509	AW296078	2668	5p13.1-p12	Hs.248114	86	neural crest cell migration extracellular region anti-apoptosis signal transduction nervous system development growth factor activity adult locomotory behavior positive regulation of specific transcription from RNA polymerase II promoter neuron projection development positive regulation of monooxygenase activity positive regulation of dopamine secretion protein homodimerization activity negative regulation of neuron apoptosis mRNA stabilization regulation of dopamine uptake
229256_at	-0.924	7.385	-3.558	2.806e-03	0.099	-1.550	PGM2L1	phosphoglucomutase 2-like 1	11	-73719008	AV724329	283209	11q13.4	Hs.26612	6	carbohydrate metabolic process glucose metabolic process transferase activity isomerase activity intramolecular transferase activity, phosphotransferases glucose-1,6-bisphosphate synthase activity	Starch and sucrose metabolism
203938_s_at	0.328	6.181	3.558	2.808e-03	0.099	-1.551	TAF1C	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	16	-82768961	NM_005679	9013	16q24	Hs.153022	17	DNA binding RNA polymerase I transcription factor activity nucleus nucleoplasm transcription transcription from RNA polymerase I promoter transcription from RNA polymerase II promoter general RNA polymerase II transcription factor activity
226452_at	0.350	6.503	3.558	2.808e-03	0.099	-1.551	PDK1	pyruvate dehydrogenase kinase, isozyme 1	2	173129024	AU146532	5163	2q31.1	Hs.470633	52	two-component sensor activity nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrial matrix carbohydrate metabolic process glucose metabolic process signal transduction small GTPase mediated signal transduction transferase activity peptidyl-histidine phosphorylation	T cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway
205934_at	-0.776	6.897	-3.557	2.812e-03	0.099	-1.552	PLCL1	phospholipase C-like 1	2	198377670, 198377777	NM_006226	5334	2q33	Hs.153322 Hs.593586	8	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
204135_at	-0.680	8.536	-3.556	2.817e-03	0.099	-1.554	FILIP1L	filamin A interacting protein 1-like	3	-101049461, -101049461, -101034677	NM_014890	11259	3q12.1	Hs.104672	8	molecular_function nucleus cytoplasm biological_process membrane myosin complex
201655_s_at	0.427	8.035	3.556	2.818e-03	0.099	-1.554	HSPG2	heparan sulfate proteoglycan 2	1	-22021323	M85289	3339	1p36.1-p34	Hs.562227	60	protein binding extracellular region basement membrane cell adhesion	ECM-receptor interaction
223093_at	-0.537	6.531	-3.556	2.819e-03	0.099	-1.554	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	T99215	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
204681_s_at	0.635	5.967	3.555	2.824e-03	0.099	-1.556	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	7	-22124432	NM_012294	9771	7p15.3	Hs.174768 Hs.713217	10	intracellular nucleus nervous system development Rap guanyl-nucleotide exchange factor activity GTP-dependent protein binding regulation of small GTPase mediated signal transduction
210299_s_at	-0.557	12.759	-3.555	2.825e-03	0.099	-1.556	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF063002	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
208837_at	0.344	5.330	3.555	2.826e-03	0.099	-1.556	TMED3	transmembrane emp24 protein transport domain containing 3	15	77390545	BC000027	23423	15q24-q25	Hs.513058	6	Golgi apparatus protein transport membrane integral to membrane
203813_s_at	0.445	4.187	3.554	2.828e-03	0.099	-1.557	SLIT3	slit homolog 3 (Drosophila)	5	-168025648	NM_003062	6586	5q35	Hs.604116	17	structural molecule activity calcium ion binding protein binding extracellular region extracellular space multicellular organismal development axon guidance central nervous system development organ morphogenesis cell differentiation	Axon guidance
203408_s_at	-0.819	9.727	-3.554	2.829e-03	0.099	-1.557	SATB1	SATB homeobox 1	3	-18364269, -18364269	NM_002971	6304	3p23	Hs.517717	34	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent sequence-specific DNA binding
230876_at	0.662	2.974	3.553	2.837e-03	0.099	-1.560	LOC169834	hypothetical protein LOC169834	9	-114799220	AI827906	169834	9q32	Hs.192877	1
225914_s_at	-0.441	4.879	-3.552	2.842e-03	0.100	-1.562	CAB39L	calcium binding protein 39-like	13	-48780786, -48780786	AW242839	81617	13q14.2	Hs.87159	9	protein binding	mTOR signaling pathway
204308_s_at	0.295	6.888	3.551	2.846e-03	0.100	-1.563	TECPR2	tectonin beta-propeller repeat containing 2	14	101899130	NM_014844	9895	14q32.31	Hs.195667	3
228909_at	0.322	4.595	3.551	2.850e-03	0.100	-1.564	LOC642852	hypothetical LOC642852	21	45532394	AW131553	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
201457_x_at	-0.415	6.984	-3.550	2.852e-03	0.100	-1.565	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	10	124903749	AF081496	9184	10q26	Hs.418533	28	kinetochore protein binding nucleus nucleolus cytosol mitosis mitotic cell cycle checkpoint cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle
201316_at	-0.573	8.090	-3.550	2.855e-03	0.100	-1.566	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	7	-42922986	AL523904	5683	7p13	Hs.333786	48	threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
213961_s_at	0.468	4.398	3.549	2.861e-03	0.100	-1.568	TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	11	62295450	AI077556	10629	11q12.3	Hs.714400	13	histone deacetylase complex DNA binding RNA polymerase II transcription factor activity transcription coactivator activity histone acetyltransferase activity protein binding nucleus chromatin remodeling transcription initiation regulation of transcription from RNA polymerase II promoter transcription initiation factor activity STAGA complex histone H3 acetylation regulation of transcription factor activity	Basal transcription factors
213258_at	0.536	7.151	3.549	2.861e-03	0.100	-1.568	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	2	-188051550, -188037202	BF511231	7035	2q32	Hs.516578	118	serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway	Complement and coagulation cascades
227666_at	0.264	4.735	3.549	2.863e-03	0.100	-1.568	DCLK2	doublecortin-like kinase 2	4	151219529	AI523594	166614	4q31.23-q31.3	Hs.591683	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation intracellular signaling cascade transferase activity
203234_at	0.446	6.482	3.548	2.865e-03	0.100	-1.569	UPP1	uridine phosphorylase 1	7	48094879, 48095270	NM_003364	7378	7p12.3	Hs.488240	11	uridine phosphorylase activity uridine phosphorylase activity cytoplasm cytosol nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine nucleotide metabolic process nucleoside metabolic process nucleotide catabolic process uridine metabolic process	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways
232349_x_at	-0.589	9.489	-3.547	2.870e-03	0.100	-1.571	DCAF6	DDB1 and CUL4 associated factor 6	1	166172531	BF671187	55827	1q24.2	Hs.435741	10	nucleus ligand-dependent nuclear receptor transcription coactivator activity
202760_s_at	1.018	6.045	3.547	2.870e-03	0.100	-1.571	PALM2-AKAP2	PALM2-AKAP2 readthrough transcript	9	111582397, 111582409	NM_007203	445815	9q31-q33	Hs.591908	8
223595_at	0.712	4.791	3.546	2.880e-03	0.100	-1.574	TMEM133	transmembrane protein 133	11	100368020	AF247167	83935	11q22.1	Hs.44004	2	membrane integral to membrane
226453_at	-0.408	7.199	-3.545	2.884e-03	0.100	-1.575	RNASEH2C	ribonuclease H2, subunit C	11	-65241719	BF982002	84153	11q13.1	Hs.718438	9	nucleus	DNA replication
217883_at	-0.326	11.057	-3.545	2.886e-03	0.100	-1.576	MMADHC	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria	2	-150134395	NM_015702	27249	2q23.2	Hs.5324	7	mitochondrion
202059_s_at	-0.583	7.441	-3.544	2.891e-03	0.100	-1.577	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	NM_002264	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
201581_at	-0.527	8.777	-3.543	2.895e-03	0.100	-1.579	TMX4	thioredoxin-related transmembrane protein 4	20	-7909715	BF572868	56255	20p12	Hs.169358	11	mitochondrion transport membrane integral to membrane electron transport chain cell redox homeostasis
201580_s_at	-0.567	7.082	-3.542	2.900e-03	0.100	-1.580	TMX4	thioredoxin-related transmembrane protein 4	20	-7909715	AL544094	56255	20p12	Hs.169358	11	mitochondrion transport membrane integral to membrane electron transport chain cell redox homeostasis
41858_at	0.351	6.059	3.540	2.912e-03	0.101	-1.584	PGAP2	post-GPI attachment to proteins 2	11	3775529, 3775624, 3775707, 3775765, 3785815, 3786341	AL049261	27315	11p15.5	Hs.133968	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus GPI anchor biosynthetic process protein transporter activity membrane integral to membrane
202258_s_at	0.402	8.633	3.540	2.913e-03	0.101	-1.584	N4BP2L2	NEDD4 binding protein 2-like 2	13	-31989029, -31904929	U50532	10443	13q13.1	Hs.507680	4	molecular_function cellular_component biological_process
222617_s_at	-0.571	7.394	-3.539	2.921e-03	0.101	-1.587	C10orf84	chromosome 10 open reading frame 84	10	-120058561	AI147026	63877	10q26.11	Hs.372309	5
231837_at	-0.703	7.163	-3.539	2.922e-03	0.101	-1.587	USP28	ubiquitin specific peptidase 28	11	-113173806	AB040948	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
241793_at	-1.442	9.582	-3.538	2.929e-03	0.101	-1.589	ZMYND17	zinc finger, MYND-type containing 17	10	-74853342	BE674227	118490	10q22.2	Hs.631823	2	zinc ion binding metal ion binding
219161_s_at	0.361	5.826	3.537	2.931e-03	0.101	-1.590	CKLF	chemokine-like factor	16	65143966, 65143972	NM_016951	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
205237_at	0.309	3.965	3.537	2.932e-03	0.101	-1.591	FCN1	ficolin (collagen/fibrinogen domain containing) 1	9	-136941254	NM_002003	2219	9q34	Hs.440898	20	antigen binding receptor binding calcium ion binding sugar binding extracellular region signal transduction opsonization
204115_at	0.699	8.538	3.535	2.946e-03	0.101	-1.595	GNG11	guanine nucleotide binding protein (G protein), gamma 11	7	93388951	NM_004126	2791	7q21	Hs.83381	14	GTPase activity signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
229585_at	0.282	3.407	3.534	2.950e-03	0.101	-1.596	ADAMTSL1	ADAMTS-like 1	9	18464103, 18464103	AI803088	92949	9p22.2-p22.1	Hs.522019	10	extracellular region proteinaceous extracellular matrix peptidase activity metallopeptidase activity zinc ion binding
225195_at	-0.620	6.934	-3.534	2.950e-03	0.101	-1.596	DPH3	DPH3, KTI11 homolog (S. cerevisiae)	3	-16273572	AI825858	285381	3p25.1	Hs.388087	8	protein binding nucleus cytoplasm zinc ion binding peptidyl-diphthamide biosynthetic process from peptidyl-histidine metal ion binding negative regulation of protein secretion positive regulation of binding
219428_s_at	0.276	6.736	3.534	2.950e-03	0.101	-1.596	PXMP4	peroxisomal membrane protein 4, 24kDa	20	-31754210	BF057649	11264	20q11.22	Hs.654857	8	membrane fraction peroxisome peroxisomal membrane membrane integral to membrane
202457_s_at	-0.713	9.104	-3.534	2.953e-03	0.101	-1.597	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	AA911231	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
1559101_at	0.366	5.469	3.533	2.953e-03	0.101	-1.597	FYN	FYN oncogene related to SRC, FGR, YES	6	-112089177, -112089177, -112089177	AK090692	2534	6q21	Hs.390567	326	nucleotide binding glycoprotein binding non-membrane spanning protein tyrosine kinase activity ATP binding endosome cytosol plasma membrane protein amino acid phosphorylation calcium ion transport protein kinase cascade multicellular organismal development learning feeding behavior transferase activity manganese ion binding identical protein binding interspecies interaction between organisms metal ion binding T cell receptor signaling pathway	Axon guidance Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway Prion diseases Pathogenic Escherichia coli infection - EHEC
224927_at	0.448	6.333	3.533	2.958e-03	0.101	-1.599	KIAA1949	KIAA1949	6	-30752145, -30752145, -2092747, -2092747, -1891047, -1891047	BG251556	170954	6p21.3	Hs.696054	9	actin binding cytoplasm cytoskeleton
209342_s_at	-0.813	6.352	-3.531	2.967e-03	0.102	-1.602	IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	8	42247985	AF080158	3551	8p11.2	Hs.597664	172	nucleotide binding B cell homeostasis ATP binding cytoplasm cytosol protein amino acid phosphorylation IkappaB kinase activity transcription activator activity transferase activity identical protein binding positive regulation of NF-kappaB transcription factor activity	MAPK signaling pathway Chemokine signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Pancreatic cancer Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer
202025_x_at	0.413	7.837	3.531	2.968e-03	0.102	-1.602	ACAA1	acetyl-Coenzyme A acyltransferase 1	3	-38139204	NM_001607	30	3p23-p22	Hs.643487	17	acetyl-CoA C-acyltransferase activity protein binding cytoplasm peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process metabolic process acyltransferase activity transferase activity intracellular membrane-bounded organelle	Fatty acid metabolism Valine, leucine and isoleucine degradation Biosynthesis of unsaturated fatty acids Metabolic pathways PPAR signaling pathway
218087_s_at	-0.774	10.392	-3.531	2.970e-03	0.102	-1.603	SORBS1	sorbin and SH3 domain containing 1	10	-97061519, -97061519	NM_015385	10580	10q23.3-q24.1	Hs.719081	35	stress fiber actin binding SH3/SH2 adaptor activity SH3/SH2 adaptor activity insulin receptor binding nucleus cytoplasm cytosol cytoskeleton plasma membrane insulin receptor complex zonula adherens cell-substrate adherens junction transport insulin receptor signaling pathway glucose transport cell junction stress fiber formation membrane raft positive regulation of glycogen biosynthetic process positive regulation of glucose import positive regulation of lipid biosynthetic process focal adhesion formation	PPAR signaling pathway Adherens junction Insulin signaling pathway
212666_at	-0.455	5.449	-3.530	2.972e-03	0.102	-1.603	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	7	-98462999	AB046845	57154	7q22.1	Hs.189329	34	ubiquitin-protein ligase activity protein binding intracellular cytoplasm plasma membrane protein modification process protein export from nucleus ectoderm development ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation negative regulation of ossification negative regulation of BMP signaling pathway ubiquitin-dependent SMAD protein catabolic process positive regulation of protein ubiquitination receptor catabolic process protein localization at cell surface protein ubiquitination during ubiquitin-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process activin binding I-SMAD binding R-SMAD binding	Ubiquitin mediated proteolysis Endocytosis TGF-beta signaling pathway
1560128_x_at	0.367	5.796	3.530	2.975e-03	0.102	-1.604	C5orf56	chromosome 5 open reading frame 56	5	131774571	AL713721	441108	5q31.1	Hs.658288	1
235579_at	-0.733	6.718	-3.529	2.980e-03	0.102	-1.606	SFRS2IP	splicing factor, arginine/serine-rich 2, interacting protein	12	-44599180	AA679858	9169	12q12	Hs.715491	11	spliceosome assembly protein binding nucleus DNA-directed RNA polymerase II, core complex mRNA processing zinc ion binding RNA splicing RNA splicing factor activity, transesterification mechanism
208966_x_at	0.493	5.949	3.529	2.983e-03	0.102	-1.607	IFI16	interferon, gamma-inducible protein 16	1	157246305	AF208043	3428	1q22	Hs.380250	42	DNA binding double-stranded DNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm regulation of transcription, DNA-dependent cell proliferation response to virus transcription repressor activity myeloid cell differentiation monocyte differentiation DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
212032_s_at	-0.450	7.334	-3.528	2.987e-03	0.102	-1.608	PTOV1	prostate tumor overexpressed 1	19	55046227	AL046054	53635	19q13.33	Hs.587979	11	nucleus cytoplasm plasma membrane regulation of transcription perinuclear region of cytoplasm
214844_s_at	-0.593	9.310	-3.528	2.988e-03	0.102	-1.608	DOK5	docking protein 5	20	52525672	AL050069	55816	20q13.2	Hs.656582	10	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
221143_at	-0.813	4.456	-3.527	2.995e-03	0.102	-1.610	RPA4	replication protein A4, 34kDa	X	96025667	NM_013347	29935	Xq21.33	Hs.659349	9	nucleic acid binding single-stranded DNA binding nucleus DNA replication factor A complex DNA replication DNA replication initiation	DNA replication Nucleotide excision repair Mismatch repair Homologous recombination
204528_s_at	-0.446	8.114	-3.526	2.999e-03	0.102	-1.612	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	NM_004537	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
1557131_at	0.365	3.969	3.526	3.000e-03	0.102	-1.612	LOC254100	hypothetical protein LOC254100	11		BQ287966	254100	11q13.1	Hs.595927	1
206142_at	0.490	2.842	3.525	3.004e-03	0.102	-1.613	ZNF135	zinc finger protein 135	19	63262423	NM_003436	7694	19q13.4	Hs.85863	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
219315_s_at	0.361	6.350	3.525	3.007e-03	0.102	-1.614	TMEM204	transmembrane protein 204	16	1524231	NM_024600	79652	16p13.3	Hs.459652	7	plasma membrane adherens junction response to stress integral to membrane cell junction
200853_at	-0.529	8.798	-3.524	3.013e-03	0.102	-1.616	H2AFZ	H2A histone family, member Z	4	-101088266	NM_002106	3015	4q24	Hs.119192	37	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
228162_at	-0.446	5.573	-3.524	3.014e-03	0.102	-1.616	ESD	esterase D/formylglutathione hydrolase	13	-46243391	AA193515	2098	13q14.1-q14.2	Hs.432491	27	carboxylesterase activity cytoplasm biological_process cytoplasmic membrane-bounded vesicle S-formylglutathione hydrolase activity
238944_at	0.629	6.368	3.524	3.014e-03	0.102	-1.616	ZNF404	zinc finger protein 404	19	-49068354	AI393706	342908	19q13.31	Hs.76561	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213803_at	-0.489	7.794	-3.522	3.023e-03	0.102	-1.619	KPNB1	karyopherin (importin) beta 1	17	43082273	BG545463	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
225632_s_at	0.484	5.494	3.522	3.024e-03	0.102	-1.619	RAB43	RAB43, member RAS oncogene family	3	-130289107	BE736242	339122	3q21.3	Hs.709807	6	nucleotide binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport
202374_s_at	-0.301	6.766	-3.522	3.025e-03	0.102	-1.620	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	NM_012414	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
41644_at	0.451	7.141	3.521	3.029e-03	0.102	-1.621	SASH1	SAM and SH3 domain containing 1	6	148705421	AB018333	23328	6q24.3	Hs.193133	12	protein binding
1555837_s_at	-0.414	9.723	-3.521	3.030e-03	0.102	-1.621	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	4	57539865	BE614461	5431	4q12	Hs.602757	92	magnesium ion binding nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
222437_s_at	-0.401	9.163	-3.521	3.031e-03	0.102	-1.621	VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	2	-86584063	BC004419	51652	2p24.3-p24.1	Hs.591582	25	protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division	Endocytosis
217995_at	-0.497	9.138	-3.521	3.033e-03	0.102	-1.622	SQRDL	sulfide quinone reductase-like (yeast)	15	43714547	NM_021199	58472	15q15	Hs.511251	6	mitochondrion mitochondrial inner membrane oxidoreductase activity oxidation reduction
227195_at	0.738	5.934	3.520	3.038e-03	0.102	-1.623	ZNF503	zinc finger protein 503	10	-76827610	AA603467	84858	10q22.2	Hs.195710	6	intracellular nucleus zinc ion binding regulation of transcription metal ion binding
209366_x_at	0.392	7.625	3.519	3.040e-03	0.102	-1.624	CYB5A	cytochrome b5 type A (microsomal)	18	-70071506	M22865	1528	18q23	Hs.465413	38	aldo-keto reductase activity cytochrome-c oxidase activity cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum microsome transport membrane integral to membrane heme binding electron transport chain metal ion binding
222092_at	0.305	5.431	3.519	3.046e-03	0.102	-1.626	PTPN21	protein tyrosine phosphatase, non-receptor type 21	14	-88001874	BF116199	11099	14q31.3	Hs.437040	10	protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity
211715_s_at	0.742	7.004	3.518	3.048e-03	0.102	-1.626	BDH1	3-hydroxybutyrate dehydrogenase, type 1	3	-198721050, -198721050	BC005844	622	3q29	Hs.274539	11	3-hydroxybutyrate dehydrogenase activity 3-hydroxybutyrate dehydrogenase activity binding mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix oxidoreductase activity oxidation reduction	Synthesis and degradation of ketone bodies Butanoate metabolism Metabolic pathways
211323_s_at	0.506	4.727	3.518	3.049e-03	0.102	-1.627	ITPR1	inositol 1,4,5-triphosphate receptor, type 1	3	4510033	L38019	3708	3p26-p25	Hs.567295 Hs.715765	87	response to hypoxia ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium channel activity calcium ion binding protein binding endoplasmic reticulum ion transport calcium ion transport signal transduction cell death calcium ion transmembrane transporter activity membrane integral to membrane platelet dense granule membrane platelet dense tubular network membrane	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease Huntington's disease
239435_x_at	0.346	6.468	3.517	3.054e-03	0.102	-1.628	SHROOM1	shroom family member 1	5	-132185910	AA588854	134549	5q31.1	Hs.519574	4	cell morphogenesis cytoplasm cytoskeleton microtubule myosin II complex actin filament binding actin filament bundle formation
209621_s_at	-0.696	12.315	-3.517	3.057e-03	0.102	-1.629	PDLIM3	PDZ and LIM domain 3	4	-186659844	AF002280	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
201613_s_at	0.397	5.325	3.517	3.057e-03	0.102	-1.629	AP1G2	adaptor-related protein complex 1, gamma 2 subunit	14	-23098616	BC000519	8906	14q11.2	Hs.343244	23	protein binding cytoplasm endosome Golgi-associated vesicle plasma membrane intracellular protein transport protein transporter activity vesicle-mediated transport membrane coat AP-1 adaptor complex transport vesicle cytoplasmic vesicle interspecies interaction between organisms
219600_s_at	-0.885	6.912	-3.516	3.059e-03	0.102	-1.630	TMEM50B	transmembrane protein 50B	21	-33743317	NM_006134	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
220992_s_at	-0.612	7.704	-3.516	3.061e-03	0.102	-1.630	C1orf25	chromosome 1 open reading frame 25	1	-183353840	NM_030934	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
225782_at	-0.775	9.363	-3.516	3.061e-03	0.102	-1.631	MSRB3	methionine sulfoxide reductase B3	12	63958754	AW027333	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
204215_at	0.543	5.143	3.516	3.062e-03	0.102	-1.631	C7orf23	chromosome 7 open reading frame 23	7	-86663413	NM_024315	79161	7q21.1-q21.2	Hs.719226	4	membrane integral to membrane
201136_at	-0.709	7.879	-3.514	3.073e-03	0.102	-1.634	PLP2	proteolipid protein 2 (colonic epithelium-enriched)	X	48915216	NM_002668	5355	Xp11.23	Hs.77422	12	protein binding membrane fraction endoplasmic reticulum endoplasmic reticulum membrane plasma membrane ion transport chemotaxis ion transmembrane transporter activity integral to membrane cytokine-mediated signaling pathway chemokine binding
213168_at	-0.473	7.962	-3.514	3.076e-03	0.102	-1.635	SP3	Sp3 transcription factor	2	-174481504, -174481503	AU145005	6670	2q31	Hs.531587	126	ossification natural killer cell differentiation trophectodermal cell differentiation liver development embryonic placenta development DNA binding chromatin binding double-stranded DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription activator activity transcription repressor activity B cell differentiation T cell differentiation megakaryocyte differentiation monocyte differentiation lung development granulocyte differentiation enucleate erythrocyte differentiation metal ion binding embryonic camera-type eye morphogenesis embryonic skeletal system development embryonic process involved in female pregnancy definitive hemopoiesis
232184_at	-0.309	2.824	-3.514	3.077e-03	0.102	-1.635	ALS2	amyotrophic lateral sclerosis 2 (juvenile)	2	-202332427, -202273231	AK023024	57679	2q33.1	Hs.471096 Hs.621812	36	ruffle guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity protein binding intracellular early endosome centrosome cytosol endosome organization cell death Rab guanyl-nucleotide exchange factor activity Rab GTPase binding Rab GTPase binding lamellipodium dendrite Rac guanyl-nucleotide exchange factor activity positive regulation of Rac GTPase activity positive regulation of Rac protein signal transduction regulation of Rho protein signal transduction vesicular fraction protein homodimerization activity protein complex protein serine/threonine kinase activator activity positive regulation of protein kinase activity neuron projection morphogenesis regulation of endosome size	Amyotrophic lateral sclerosis (ALS)
228155_at	0.868	9.301	3.512	3.090e-03	0.103	-1.639	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	BF512388	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
226055_at	-0.807	7.210	-3.510	3.097e-03	0.103	-1.641	ARRDC2	arrestin domain containing 2	19	17972943, 17979976	AK000689	27106	19p13.11	Hs.515249	6
1560276_at	0.699	7.318	3.510	3.098e-03	0.103	-1.642	LOC283403	hypothetical protein LOC283403	12		BC038743	283403	12q13.13	Hs.667179	1
221932_s_at	0.395	10.590	3.510	3.100e-03	0.103	-1.642	GLRX5	glutaredoxin 5	14	95071075	AA133341	51218	14q32.13	Hs.532683 Hs.719204	5	mitochondrion electron carrier activity protein disulfide oxidoreductase activity cell redox homeostasis
229980_s_at	-0.511	9.177	-3.510	3.102e-03	0.103	-1.643	SNX5	sorting nexin 5	20	-17870243, -17870243	AA131508	27131	20p11	Hs.316890	14	protein binding cell communication protein transport phosphoinositide binding
201713_s_at	-0.389	9.152	-3.509	3.104e-03	0.103	-1.643	RANBP2	RAN binding protein 2	2	108702368	D42063	5903	2q12.3	Hs.199561 Hs.715056	61	peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport
1553071_a_at	-0.852	6.578	-3.509	3.105e-03	0.103	-1.644	MYOZ3	myozenin 3	5	150020596	NM_133371	91977	5q33.1	Hs.91626	7	protein binding cytoplasm Z disc
210250_x_at	-0.509	10.180	-3.508	3.111e-03	0.103	-1.646	ADSL	adenylosuccinate lyase	22	39072449	AF067854	158	22q13.1 22q13.2	Hs.75527	29	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity cytoplasm cytosol AMP biosynthetic process purine ribonucleotide biosynthetic process lyase activity protein tetramerization (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
225892_at	-0.526	7.854	-3.508	3.115e-03	0.103	-1.647	IREB2	iron-responsive element binding protein 2	15	76517572	BF438417	3658	15q25.1	Hs.436031	28	RNA binding iron ion binding cytoplasm cytosol regulation of translation protoporphyrinogen IX biosynthetic process cellular iron ion homeostasis metabolic process post-embryonic development regulation of gene expression iron-responsive element binding erythrocyte homeostasis metal ion binding intestinal absorption 4 iron, 4 sulfur cluster binding
209536_s_at	0.448	6.265	3.507	3.117e-03	0.103	-1.647	EHD4	EH-domain containing 4	15	-39978932	AF320070	30844	15q11.1	Hs.143703	11	nucleotide binding nucleic acid binding GTPase activity calcium ion binding protein binding ATP binding GTP binding nucleus endosome endoplasmic reticulum membrane	Endocytosis
226764_at	0.367	5.671	3.506	3.125e-03	0.103	-1.650	ZNF827	zinc finger protein 827	4	-146901337	BG542955	152485	4q31.21-q31.22	Hs.133916 Hs.633543	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
239261_s_at	0.316	4.830	3.506	3.128e-03	0.103	-1.650	CORIN	corin, serine peptidase	4	-47290774	AI338960	10699	4p13-p12	Hs.518618	15	serine-type endopeptidase activity scavenger receptor activity plasma membrane integral to plasma membrane proteolysis lipid metabolic process regulation of blood pressure peptidase activity anatomical structure morphogenesis cell surface
1570020_at	0.314	2.756	3.504	3.135e-03	0.103	-1.653	AACSL	acetoacetyl-CoA synthetase-like	5	-178124469	BC024222	729522	5q35.3	Hs.382790	2
212928_at	0.347	6.685	3.504	3.139e-03	0.103	-1.654	TSPYL4	TSPY-like 4	6	-116677823	AL050331	23270	6q22.1	Hs.284141	7	nucleus nucleosome assembly
220107_s_at	-0.335	5.537	-3.504	3.140e-03	0.103	-1.654	FAM164C	family with sequence similarity 164, member C	14	74606051	NM_024643	79696	14q24.3	Hs.48642	5
223737_x_at	0.298	2.818	3.503	3.143e-03	0.103	-1.655	CHST9	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9	18	-22740443	AF239821	83539	18q11.2	Hs.44584	8	N-acetylgalactosamine 4-O-sulfotransferase activity N-acetylgalactosamine 4-O-sulfotransferase activity extracellular region Golgi apparatus sulfur metabolic process membrane integral to membrane carbohydrate biosynthetic process transferase activity proteoglycan biosynthetic process glycosaminoglycan metabolic process hormone biosynthetic process
201237_at	-0.723	9.127	-3.503	3.146e-03	0.103	-1.656	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	7	116289798	AV685920	830	7q31.2-q31.3	Hs.446123	14	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
1552790_a_at	-0.566	6.847	-3.503	3.147e-03	0.103	-1.656	SEC62	SEC62 homolog (S. cerevisiae)	3	171167273	NM_153039	7095	3q26.2	Hs.622596	10	receptor activity endoplasmic reticulum cytoskeleton cotranslational protein targeting to membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport
229085_at	-1.784	5.389	-3.502	3.148e-03	0.103	-1.657	LRRC3B	leucine rich repeat containing 3B	3	26639303	AW027879	116135	3p24	Hs.517868	10	protein binding membrane integral to membrane
225776_at	0.354	5.867	3.502	3.149e-03	0.103	-1.657	RBMS2	RNA binding motif, single stranded interacting protein 2	12	55201875	AW205585	5939	12q13.3	Hs.505729 Hs.683360	7	nucleotide binding RNA binding nucleus RNA processing
209749_s_at	0.294	3.581	3.502	3.149e-03	0.103	-1.657	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	17	58908165, 58915908	AI623989	1636	17q23.3	Hs.654434	1473	kidney development angiotensin catabolic process in blood regulation of systemic arterial blood pressure by renin-angiotensin carboxypeptidase activity extracellular region extracellular space membrane fraction endosome plasma membrane proteolysis drug binding regulation of blood pressure peptidase activity metallopeptidase activity metallopeptidase activity peptidyl-dipeptidase activity peptidyl-dipeptidase activity zinc ion binding external side of plasma membrane regulation of smooth muscle cell migration integral to membrane regulation of vasoconstriction chloride ion binding bradykinin receptor binding mononuclear cell proliferation regulation of vasodilation hormone catabolic process hormone catabolic process peptide catabolic process metal ion binding arachidonic acid secretion hemopoietic stem cell differentiation	Renin-angiotensin system Hypertrophic cardiomyopathy (HCM)
227970_at	-0.608	8.917	-3.501	3.156e-03	0.103	-1.659	GPR157	G protein-coupled receptor 157	1	-9087062	AK026883	80045	1p36.23	Hs.632367	5	G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane
225607_at	-0.393	8.256	-3.501	3.157e-03	0.103	-1.659	CCDC43	coiled-coil domain containing 43	17	-40110330	AI948491	124808	17q21.31	Hs.579115	2
242528_at	0.276	3.103	3.501	3.158e-03	0.103	-1.660	LOC285943	hypothetical protein LOC285943	7		AI473887	285943	7p15.2	Hs.714774	1
231718_at	-0.539	7.081	-3.501	3.159e-03	0.103	-1.660	SLU7	SLU7 splicing factor homolog (S. cerevisiae)	5	-159761225	NM_006425	10569	5q33.3	Hs.435342	9	alternative nuclear mRNA splicing, via spliceosome second spliceosomal transesterification activity nuclear mRNA 3'-splice site recognition nucleic acid binding nucleus spliceosomal complex cytoplasm mRNA processing zinc ion binding RNA splicing nuclear speck small nuclear ribonucleoprotein complex pre-mRNA 3'-splice site binding metal ion binding
203729_at	0.380	5.601	3.501	3.160e-03	0.103	-1.660	EMP3	epithelial membrane protein 3	19	53520440	NM_001425	2014	19q13.3	Hs.9999	14	negative regulation of cell proliferation membrane integral to membrane cell growth
231014_at	0.301	4.971	3.500	3.162e-03	0.103	-1.661	TRIM50	tripartite motif-containing 50	7	-72364470	BG413545	135892	7q11.23	Hs.647053	4	protein binding intracellular cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
222648_at	0.354	5.401	3.500	3.166e-03	0.103	-1.662	TBC1D16	TBC1 domain family, member 16	17	-75528413	BC000248	125058	17q25.3	Hs.369819	4	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
213603_s_at	0.471	5.445	3.499	3.168e-03	0.103	-1.662	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	22	-35951255	BE138888	5880	22q13.1	Hs.517601	58	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction nuclear envelope cytoplasm chemotaxis signal transduction small GTPase mediated signal transduction positive regulation of cell proliferation regulation of hydrogen peroxide metabolic process cell projection assembly actin cytoskeleton organization regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Pancreatic cancer
226004_at	-0.355	6.141	-3.499	3.171e-03	0.103	-1.663	CABLES2	Cdk5 and Abl enzyme substrate 2	20	-60397080	AI910855	81928	20q13.33	Hs.301040	5	cyclin-dependent protein kinase regulator activity regulation of cell division regulation of cell cycle
202004_x_at	0.329	9.011	3.499	3.174e-03	0.103	-1.664	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	1	159550789	NM_003001	6391	1q23.3	Hs.444472	27	succinate dehydrogenase activity iron ion binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane tricarboxylic acid cycle transport electron carrier activity membrane integral to membrane electron transport chain respiratory chain complex II metal ion binding	Citrate cycle (TCA cycle) Oxidative phosphorylation Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
242272_at	0.348	5.954	3.499	3.174e-03	0.103	-1.664	ZNF785	zinc finger protein 785	16	-30499494	AI375066	146540	16p11.2	Hs.513509	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
241602_at	0.262	6.195	3.498	3.180e-03	0.103	-1.666	ZNF582	zinc finger protein 582	19	-61586459	BG432829	147948	19q13.43	Hs.244391	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
232052_at	0.264	6.015	3.497	3.186e-03	0.103	-1.668	LOC440944	hypothetical LOC440944	3	-9405536	AL110136	440944	3p25.3	Hs.598958 Hs.652556	2
225161_at	-0.505	7.141	-3.496	3.188e-03	0.103	-1.668	GFM1	G elongation factor, mitochondrial 1	3	159845010	AI659020	85476	3q25.1-q26.2	Hs.518355	11	nucleotide binding translation elongation factor activity GTPase activity GTP binding intracellular mitochondrion translational elongation
235532_at	0.340	3.365	3.495	3.194e-03	0.103	-1.670	PIGM	phosphatidylinositol glycan anchor biosynthesis, class M	1	-158264085	AI631888	93183	1q23.2	Hs.552810	7	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring hexosyl groups	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
1552326_a_at	-0.430	3.999	-3.495	3.196e-03	0.103	-1.671	CCDC11	coiled-coil domain containing 11	18	-46007561	NM_145020	220136	18q21.1	Hs.658630	4	molecular_function cellular_component biological_process
218563_at	0.299	11.096	3.495	3.197e-03	0.103	-1.671	NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	19	59297971	NM_004542	4696	19q13.42	Hs.198269	7	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
202353_s_at	-0.438	9.140	-3.495	3.198e-03	0.103	-1.671	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	17	-62767081, -62767080	NM_002816	5718	17q24.2	Hs.646575	39	protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
205693_at	-1.129	11.618	-3.494	3.201e-03	0.103	-1.672	TNNT3	troponin T type 3 (skeletal, fast)	11	1897374	NM_006757	7140	11p15.5	Hs.73454	21	skeletal muscle contraction actin binding tropomyosin binding tropomyosin binding troponin complex regulation of striated muscle contraction troponin C binding calcium-dependent ATPase activity troponin I binding regulation of ATPase activity calcium-dependent protein binding
202090_s_at	0.306	11.887	3.494	3.204e-03	0.103	-1.673	UQCR	ubiquinol-cytochrome c reductase, 6.4kDa subunit	19	-1548170	NM_006830	10975	19p13.3	Hs.8372	4	mitochondrion mitochondrial inner membrane mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity electron carrier activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
213883_s_at	-0.387	8.535	-3.492	3.215e-03	0.104	-1.676	TM2D1	TM2 domain containing 1	1	-61919306	AA012917	83941	1p31.3	Hs.656790	5	beta-amyloid binding G-protein coupled receptor activity integral to plasma membrane apoptosis induction of apoptosis by extracellular signals membrane
236381_s_at	-0.598	5.023	-3.492	3.218e-03	0.104	-1.677	WDR8	WD repeat domain 8	1	-3537191	AW572779	49856	1p36.3	Hs.31714	8	protein binding cytoplasm
206137_at	0.358	4.715	3.492	3.218e-03	0.104	-1.677	RIMS2	regulating synaptic membrane exocytosis 2	8	104582151, 104900591	NM_014677	9699	8q22.3	Hs.655271	18	protein binding plasma membrane intracellular protein transport zinc ion binding Rab GTPase binding cell junction synapse metal ion binding
233750_s_at	-0.652	5.204	-3.491	3.223e-03	0.104	-1.678	C1orf25	chromosome 1 open reading frame 25	1	-183353840	AL109865	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
215051_x_at	0.370	6.210	3.490	3.230e-03	0.104	-1.680	AIF1	allograft inflammatory factor 1	6	31690972, 31691011, 31691767, 3029118, 3029157, 3029913, 2830581, 2830620, 2831376	BF213829	199	6p21.3	Hs.76364	38	calcium ion binding nucleus response to stress inflammatory response cell cycle arrest negative regulation of cell proliferation
221231_s_at	-0.330	4.221	-3.489	3.236e-03	0.104	-1.682	C14orf102	chromosome 14 open reading frame 102	14	-89814150	NM_017970	55051	14q32.11	Hs.528131	4	protein binding
206287_s_at	-1.090	7.677	-3.488	3.243e-03	0.104	-1.684	ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	3	-52822045	NM_002218	3700	3p21-p14	Hs.709406	19	serine-type endopeptidase inhibitor activity extracellular region acute-phase response hyaluronan metabolic process
210976_s_at	-0.599	12.191	-3.488	3.244e-03	0.104	-1.684	PFKM	phosphofructokinase, muscle	12	46799294	U24183	5213	12q13.3	Hs.75160	35	nucleotide binding magnesium ion binding 6-phosphofructokinase activity 6-phosphofructokinase activity 6-phosphofructokinase activity ATP binding sugar binding soluble fraction cytoplasm cytosol cytosol 6-phosphofructokinase complex fructose 6-phosphate metabolic process glycolysis protein C-terminus binding kinase activity apical plasma membrane transferase activity kinase binding fructose 1,6-bisphosphate metabolic process positive regulation of insulin secretion glucose homeostasis identical protein binding muscle maintenance protein oligomerization fructose-6-phosphate binding	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Galactose metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
221433_at	1.682	5.684	3.488	3.245e-03	0.104	-1.685	FGF21	fibroblast growth factor 21	19	53951155	NM_019113	26291	19q13.1-qter	Hs.283015	17	extracellular region soluble fraction signal transduction cell-cell signaling growth factor activity	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
202965_s_at	1.123	5.376	3.487	3.249e-03	0.104	-1.686	CAPN6	calpain 6	X	-110374986	NM_014289	827	Xq23	Hs.496593	8	calcium-dependent cysteine-type endopeptidase activity intracellular proteolysis
225426_at	-0.859	8.192	-3.487	3.252e-03	0.104	-1.686	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	AW195360	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
202845_s_at	-0.390	7.788	-3.487	3.254e-03	0.104	-1.687	RALBP1	ralA binding protein 1	18	9465529	NM_006788	10928	18p11.3	Hs.528993 Hs.719181	42	GTPase activator activity protein binding intracellular transport chemotaxis signal transduction small GTPase mediated signal transduction membrane ATPase activity Ral GTPase binding Rac GTPase activator activity regulation of GTPase activity positive regulation of Cdc42 GTPase activity ATPase activity, coupled to movement of substances Rac GTPase binding	Pathways in cancer Pancreatic cancer
206393_at	-1.379	12.029	-3.486	3.254e-03	0.104	-1.687	TNNI2	troponin I type 2 (skeletal, fast)	11	1816808, 1817294, 1818007	NM_003282	7136	11p15.5	Hs.523403	29	skeletal muscle contraction actin binding protein binding nucleus troponin complex troponin T binding positive regulation of transcription
212482_at	-0.720	8.151	-3.486	3.256e-03	0.104	-1.688	RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	2	86800924	BF671894	64795	2p11.2	Hs.75277	7
200867_at	-0.587	7.326	-3.486	3.259e-03	0.104	-1.688	RNF114	ring finger protein 114	20	47986320	AL031685	55905	20q13.13	Hs.144949	9	protein binding intracellular multicellular organismal development spermatogenesis zinc ion binding cell differentiation metal ion binding
222764_at	0.696	5.550	3.486	3.259e-03	0.104	-1.688	ASRGL1	asparaginase like 1	11	61861349	AI928342	80150	11q12.3	Hs.535326	9	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity cytoplasm hydrolase activity asparagine catabolic process via L-aspartate	Alanine, aspartate and glutamate metabolism Cyanoamino acid metabolism Nitrogen metabolism Metabolic pathways
203375_s_at	-0.421	7.546	-3.486	3.259e-03	0.104	-1.689	TPP2	tripeptidyl peptidase II	13	102047286	NM_003291	7174	13q32-q33	Hs.432424	23	aminopeptidase activity serine-type endopeptidase activity cytoplasm proteolysis peptidase activity tripeptidyl-peptidase activity
232497_at	0.290	3.071	3.486	3.260e-03	0.104	-1.689	ZNF3	zinc finger protein 3	7	-99505529, -99499588	AF217988	7551	7q22.1	Hs.435302	10	transcription factor activity intracellular nucleus nucleus nucleolus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding cell differentiation identical protein binding leukocyte activation metal ion binding
218455_at	0.449	6.681	3.484	3.271e-03	0.104	-1.692	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	20	-33720024	NM_021100	9054	20q11.22	Hs.194692	14	protein binding nucleus cytoplasm mitochondrion mitochondrial matrix cytosol protein complex assembly cysteine metabolic process Mo-molybdopterin cofactor biosynthetic process metabolic process transferase activity iron incorporation into metallo-sulfur cluster pyridoxal phosphate binding cysteine desulfurase activity protein homodimerization activity	Thiamine metabolism
1556061_at	-0.666	5.164	-3.484	3.271e-03	0.104	-1.692	RPP30	ribonuclease P/MRP 30kDa subunit	10	92621688, 92621688	AI760272	10556	10q23.31	Hs.139120	16	ribonuclease P activity ribonuclease activity protein binding nucleus nucleolar ribonuclease P complex nucleolus tRNA processing hydrolase activity
213845_at	-0.702	4.027	-3.483	3.277e-03	0.104	-1.694	GRIK2	glutamate receptor, ionotropic, kainate 2	6	101953625	AL355532	2898	6q16.3-q21	Hs.98262	53	receptor activity ion channel activity extracellular-glutamate-gated ion channel activity plasma membrane integral to plasma membrane ion transport glutamate signaling pathway kainate selective glutamate receptor activity cell junction induction of programmed cell death in response to chemical stimulus synapse postsynaptic membrane regulation of short-term neuronal synaptic plasticity positive regulation of synaptic transmission neuron apoptosis	Neuroactive ligand-receptor interaction
200894_s_at	-0.492	6.051	-3.483	3.280e-03	0.104	-1.695	FKBP4	FK506 binding protein 4, 59kDa	12	2774368	AA894574	2288	12p13.33	Hs.524183 Hs.713721	47	peptidyl-prolyl cis-trans isomerase activity ATP binding GTP binding FK506 binding intracellular nucleus nucleolus cytoplasm protein folding steroid hormone receptor complex assembly copper ion transport embryo implantation isomerase activity protein binding, bridging heat shock protein binding protein complex localization glucocorticoid receptor binding male sex differentiation phosphoprotein binding
222116_s_at	0.476	5.189	3.482	3.284e-03	0.104	-1.696	TBC1D16	TBC1 domain family, member 16	17	-75528413	AL157485	125058	17q25.3	Hs.369819	4	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
221497_x_at	-0.589	7.147	-3.480	3.301e-03	0.105	-1.700	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	BC005369	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
201699_at	-0.423	9.470	-3.480	3.301e-03	0.105	-1.700	PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	14	52243645	NM_002806	5706	14q22.1	Hs.156171 Hs.718586	45	nucleotide binding proteasome complex ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process protein binding, bridging anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
218638_s_at	0.441	6.922	3.479	3.307e-03	0.105	-1.702	SPON2	spondin 2, extracellular matrix protein	4	-1150720, -1150720	NM_012445	10417	4p16.3	Hs.302963	11	protein binding extracellular region proteinaceous extracellular matrix immune response cell adhesion axon guidance
213160_at	0.322	3.634	3.478	3.310e-03	0.105	-1.703	DOCK2	dedicator of cytokinesis 2	5	168996828	D86964	1794	5q35.1	Hs.586174	20	membrane raft polarization establishment of T cell polarity formation of immunological synapse guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol cytoskeleton chemotaxis electron carrier activity membrane heme binding actin cytoskeleton organization Rac GTPase activator activity Rac guanyl-nucleotide exchange factor activity T cell receptor binding positive thymic T cell selection negative thymic T cell selection alpha-beta T cell proliferation lymphocyte chemotaxis	Chemokine signaling pathway Fc gamma R-mediated phagocytosis
206394_at	-1.621	12.029	-3.478	3.313e-03	0.105	-1.704	MYBPC2	myosin binding protein C, fast type	19	55627971	NM_004533	4606	19q13.33	Hs.85937	10	actin binding protein binding striated muscle thick filament striated muscle contraction cell adhesion structural constituent of muscle
214145_s_at	-0.554	7.427	-3.478	3.314e-03	0.105	-1.704	SPTB	spectrin, beta, erythrocytic	14	-64302901, -64282753	BG223341	6710	14q23-q24.2	Hs.417303	62	structural constituent of cytoskeleton protein binding cytoplasm cell cortex spectrin spectrin-associated cytoskeleton actin cytoskeleton intrinsic to internal side of plasma membrane protein complex actin filament binding actin filament capping
206903_at	0.250	6.093	3.478	3.314e-03	0.105	-1.704	EXOG	endo/exonuclease (5'-3'), endonuclease G-like	3	38512766	NM_005728	9941	3p21.3	Hs.517897	6	nucleic acid binding endonuclease activity cellular_component mitochondrion mitochondrial inner membrane biological_process membrane hydrolase activity metal ion binding	Apoptosis
209563_x_at	-0.384	11.120	-3.477	3.316e-03	0.105	-1.705	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	BC000454	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
218127_at	-0.754	7.185	-3.477	3.317e-03	0.105	-1.705	NFYB	nuclear transcription factor Y, beta	12	-103034987	AI804118	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
219159_s_at	0.554	3.517	3.477	3.318e-03	0.105	-1.705	SLAMF7	SLAM family member 7	1	158975700	NM_021181	57823	1q23.1-q24.1	Hs.517265	21	receptor activity cell adhesion membrane integral to membrane natural killer cell activation natural killer cell mediated cytotoxicity
206182_at	0.417	5.196	3.476	3.328e-03	0.105	-1.708	ZNF134	zinc finger protein 134	19	62817641	NM_003435	7693	19q13.4	Hs.469694	2	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226411_at	0.299	6.033	3.475	3.331e-03	0.105	-1.709	EVI5L	ecotropic viral integration site 5-like	19	7801160, 7817385	N32544	115704	19p13.2	Hs.26870	7	GTPase activator activity Rab GTPase activator activity protein binding intracellular regulation of Rab GTPase activity
227719_at	1.612	7.120	3.475	3.335e-03	0.105	-1.710	SMAD9	SMAD family member 9	13	-36320206	AA934610	4093	13q12-q14	Hs.123119	20	transcription factor activity protein binding intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol regulation of transcription, DNA-dependent transforming growth factor beta receptor signaling pathway BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	TGF-beta signaling pathway
232892_at	0.486	9.816	3.474	3.336e-03	0.105	-1.710	C20orf166	chromosome 20 open reading frame 166	20	60558104	AL449263	128826	20q13.33	Hs.86507	5
212372_at	0.915	7.144	3.474	3.339e-03	0.105	-1.711	MYH10	myosin, heavy chain 10, non-muscle	17	-8318254	AK026977	4628	17p13	Hs.16355	37	microfilament motor activity nucleotide binding cytokinesis after mitosis in utero embryonic development stress fiber neuron migration plasma membrane repair calmodulin binding ATP binding cytoplasm spindle plasma membrane cell cortex exocytosis substrate-bound cell migration, cell extension nuclear migration axon guidance brain development adult heart development biological_process cell proliferation regulation of cell shape myosin complex fourth ventricle development lateral ventricle development third ventricle development cerebellar Purkinje cell layer development actin cytoskeleton organization actin filament-based movement axon growth cone midbody actin-dependent ATPase activity neuron projection development neuromuscular junction cleavage furrow cell soma dendritic spine ADP binding neuromuscular process controlling balance actin filament binding cardiac myofibril assembly ventricular cardiac muscle cell development retina development in camera-type eye	Tight junction Regulation of actin cytoskeleton
211761_s_at	-0.355	9.436	-3.472	3.356e-03	0.105	-1.716	CACYBP	calcyclin binding protein	1	173235193, 173235514	BC005975	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
202745_at	-0.325	7.270	-3.472	3.356e-03	0.105	-1.716	USP8	ubiquitin specific peptidase 8	15	48503870	NM_005154	9101	15q21.2	Hs.644563	25	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding ubiquitin-dependent protein catabolic process peptidase activity cell proliferation SH3 domain binding	Endocytosis
208632_at	-0.675	7.818	-3.471	3.359e-03	0.105	-1.717	RNF10	ring finger protein 10	12	119456514	AL578551	9921	12q24.31	Hs.442798	10	protein binding cytoplasm zinc ion binding positive regulation of transcription metal ion binding
209090_s_at	-0.545	9.676	-3.470	3.364e-03	0.105	-1.718	SH3GLB1	SH3-domain GRB2-like endophilin B1	1	86942844	AL049597	51100	1p22	Hs.136309	28	protein insertion into mitochondrial membrane during induction of apoptosis fatty acid binding protein binding nucleus cytoplasm mitochondrion mitochondrial outer membrane microsome Golgi apparatus phosphatidic acid biosynthetic process apoptosis anti-apoptosis phospholipid biosynthetic process membrane lysophosphatidic acid acyltransferase activity protein homodimerization activity protein complex 'de novo' posttranslational protein folding	Endocytosis
209033_s_at	-0.528	9.042	-3.470	3.364e-03	0.105	-1.718	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	21	37661728, 37713076, 37714470, 37714471	D86550	1859	21q22.13	Hs.368240 Hs.719269	57	nucleotide binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding nucleus nervous system development nuclear speck transferase activity peptidyl-tyrosine phosphorylation protein self-association protein amino acid autophosphorylation
221562_s_at	0.506	6.794	3.470	3.369e-03	0.105	-1.719	SIRT3	sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)	11	-205029	AF083108	23410	11p15.5	Hs.716456	21	NAD+ ADP-ribosyltransferase activity protein binding cytoplasm mitochondrion mitochondrial matrix chromatin silencing protein amino acid ADP-ribosylation protein amino acid deacetylation zinc ion binding membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides regulation of transcription metal ion binding NAD binding
222744_s_at	0.373	6.753	3.469	3.372e-03	0.106	-1.720	TMLHE	trimethyllysine hydroxylase, epsilon	X	-154372966	AI635160	55217	Xq28	Hs.133321	12	iron ion binding mitochondrion mitochondrial matrix mitochondrial matrix electron carrier activity oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding carnitine biosynthetic process trimethyllysine dioxygenase activity oxidation reduction	Lysine degradation
208760_at	-0.898	6.956	-3.468	3.379e-03	0.106	-1.722	UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	16	1299180, 1299361, 1299638	AL031714	7329	16p13.3	Hs.302903	145	nucleotide binding synaptonemal complex ATP binding nucleus ubiquitin-dependent protein catabolic process cell cycle chromosome segregation mitosis specific transcriptional repressor activity PML body ligase activity small conjugating protein ligase activity enzyme binding HLH domain binding post-translational protein modification interspecies interaction between organisms negative regulation of transcription, DNA-dependent regulation of protein metabolic process cell division	Ubiquitin mediated proteolysis
231789_at	0.436	2.842	3.468	3.380e-03	0.106	-1.722	PCDHB15	protocadherin beta 15	5	140605330	AV722990	56121	5q31	Hs.130757	8	calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion nervous system development
213178_s_at	0.550	6.065	3.468	3.381e-03	0.106	-1.723	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	16	1696221	AB028989	23162	16p13.3	Hs.207763	23	Golgi membrane MAP-kinase scaffold activity cytoplasm vesicle-mediated transport kinesin binding protein kinase binding regulation of JNK cascade	MAPK signaling pathway
202393_s_at	-0.847	9.258	-3.468	3.382e-03	0.106	-1.723	KLF10	Kruppel-like factor 10	8	-103730182, -103730182	NM_005655	7071	8q22.2	Hs.435001	26	negative regulation of transcription from RNA polymerase II promoter skeletal system development transcription factor activity protein binding intracellular nucleus transforming growth factor beta receptor signaling pathway cell-cell signaling zinc ion binding negative regulation of cell proliferation regulation of transcription metal ion binding
223611_s_at	0.721	5.929	3.467	3.387e-03	0.106	-1.724	LNX1	ligand of numb-protein X 1	4	-54021193, -54021193	AI738919	84708	4q12	Hs.518760 Hs.624833	22	ubiquitin-protein ligase activity protein binding cytoplasm zinc ion binding ligase activity PDZ domain binding protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding protein homooligomerization
213540_at	0.592	7.653	3.467	3.388e-03	0.106	-1.725	HSD17B8	hydroxysteroid (17-beta) dehydrogenase 8	6	33280396, 4552579, 4358588	AL031228	7923	6p21.3	Hs.415058	18	estradiol 17-beta-dehydrogenase activity retinoid-X receptor activity binding cellular_component membrane fraction mitochondrion mitochondrial envelope plasma membrane estrogen biosynthetic process androgen metabolic process oxidoreductase activity thyroid hormone receptor coactivator activity vitamin D receptor binding retinoic acid receptor binding thyroid hormone receptor binding protein heterodimerization activity testosterone 17-beta-dehydrogenase activity oxidation reduction	Androgen and estrogen metabolism Metabolic pathways
227326_at	-0.551	6.757	-3.467	3.391e-03	0.106	-1.725	MXRA7	matrix-remodelling associated 7	17	-72187245, -72183403	BE966768	439921	17q25.1	Hs.250723 Hs.597019 Hs.707692	4	membrane integral to membrane
222604_at	-0.438	6.655	-3.466	3.392e-03	0.106	-1.726	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	2	-197337344	AI608833	9330	2q33.1	Hs.470996	10	transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity binding nucleus transcription, DNA-dependent 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter
218154_at	0.296	6.445	3.466	3.394e-03	0.106	-1.726	GSDMD	gasdermin D	8	144711634	NM_024736	79792	8q24.3	Hs.118983	8	cellular response to extracellular stimulus
201137_s_at	0.854	8.249	3.466	3.395e-03	0.106	-1.727	HLA-DPB1	major histocompatibility complex, class II, DP beta 1	6	33151737, 4424266, 4230157	NM_002121	3115	6p21.3	Hs.485130	221	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response membrane integral to membrane MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
211991_s_at	0.803	6.611	3.465	3.400e-03	0.106	-1.728	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	6	-33140771, -4413300, -4219191	M27487	3113	6p21.3	Hs.347270	71	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane integral to plasma membrane immune response MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
213316_at	0.643	5.321	3.464	3.411e-03	0.106	-1.731	KIAA1462	KIAA1462	10	-30343389	AL050154	57608	10p11.23	Hs.533953	4
236034_at	0.465	4.602	3.463	3.416e-03	0.106	-1.732	ANGPT2	angiopoietin 2	8	-6344580	AA083514	285	8p23.1	Hs.583870	137	angiogenesis receptor binding extracellular region extracellular space signal transduction multicellular organismal development cell differentiation
235677_at	-0.590	5.910	-3.461	3.427e-03	0.106	-1.735	SRR	serine racemase	17	2153997	BE857570	63826	17p13	Hs.461954	22	calcium ion binding protein binding ATP binding cellular amino acid metabolic process L-serine metabolic process metabolic process glycine binding isomerase activity racemase and epimerase activity, acting on amino acids and derivatives threonine racemase activity pyridoxal phosphate binding serine racemase activity protein homodimerization activity protein homotetramerization D-serine biosynthetic process	Glycine, serine and threonine metabolism
213353_at	-0.580	7.885	-3.461	3.428e-03	0.106	-1.736	ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5	17	-64752170, -64752170	BF693921	23461	17q24.3	Hs.421474	11	nucleotide binding ATP binding lysosome endosome Golgi apparatus transport membrane integral to membrane ATPase activity	ABC transporters
225825_at	-0.772	7.426	-3.461	3.432e-03	0.106	-1.736	C20orf194	chromosome 20 open reading frame 194	20	-3177947	AL110249	25943	20p13	Hs.516853	7
205052_at	0.478	8.373	3.460	3.435e-03	0.106	-1.737	AUH	AU RNA binding protein/enoyl-Coenzyme A hydratase	9	-93015917	NM_001698	549	9q22.31	Hs.175905	16	RNA binding mRNA 3'-UTR binding enoyl-CoA hydratase activity methylglutaconyl-CoA hydratase activity mitochondrion mRNA catabolic process metabolic process branched chain family amino acid catabolic process lyase activity	Valine, leucine and isoleucine degradation Metabolic pathways
223461_at	0.600	6.889	3.460	3.435e-03	0.106	-1.737	TBC1D7	TBC1 domain family, member 7	6	-13413164	AF151073	51256	6p24.1	Hs.484678	9	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
212530_at	-0.475	9.438	-3.458	3.450e-03	0.107	-1.741	NEK7	NIMA (never in mitosis gene a)-related kinase 7	1	196392730	AL080111	140609	1q31.3	Hs.24119	7	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
210613_s_at	-0.345	7.987	-3.458	3.453e-03	0.107	-1.742	SYNGR1	synaptogyrin 1	22	38075899, 38075899, 38090120	BC000731	9145	22q13.1	Hs.216226	13	integral to plasma membrane membrane cell junction melanosome synapse
208323_s_at	-0.347	3.803	-3.457	3.456e-03	0.107	-1.743	ANXA13	annexin A13	8	-124762214	NM_004306	312	8q24.13	Hs.181107	9	calcium ion binding calcium-dependent phospholipid binding plasma membrane cell differentiation
217887_s_at	-0.706	8.481	-3.457	3.457e-03	0.107	-1.743	EPS15	epidermal growth factor receptor pathway substrate 15	1	-51592523, -51592522	NM_001981	2060	1p32	Hs.83722	63	calcium ion binding protein binding cytoplasm endosome cytosol plasma membrane coated pit epidermal growth factor receptor signaling pathway cell proliferation protein transport vesicle organization SH3 domain binding	Endocytosis
204744_s_at	0.598	9.932	3.457	3.460e-03	0.107	-1.744	IARS	isoleucyl-tRNA synthetase	9	-94012445, -94012445	NM_013417	3376	9q21	Hs.445403	13	nucleotide binding isoleucine-tRNA ligase activity ATP binding soluble fraction cytoplasm isoleucyl-tRNA aminoacylation zinc ion binding ligase activity	Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis
228189_at	-0.472	6.760	-3.457	3.460e-03	0.107	-1.744	BAG4	BCL2-associated athanogene 4	8	38153262	T32429	9530	8p11.23	Hs.194726	14	receptor signaling protein activity protein binding cytoplasm protein folding apoptosis anti-apoptosis
203955_at	0.317	6.375	3.457	3.461e-03	0.107	-1.744	KIAA0649	KIAA0649	9	137511468	NM_014811	9858	9q34.3	Hs.533260	6	nucleus nucleolus
215379_x_at	0.716	6.110	3.456	3.463e-03	0.107	-1.745	IGL@	immunoglobulin lambda locus	22		AV698647	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
202815_s_at	-0.524	6.944	-3.456	3.465e-03	0.107	-1.745	HEXIM1	hexamethylene bis-acetamide inducible 1	17	40580466	NM_006460	10614	17q21.31	Hs.586945 Hs.634944 Hs.716487	28	negative regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm heart development specific transcriptional repressor activity snRNA binding regulation of transcription negative regulation of cyclin-dependent protein kinase activity
228748_at	-0.662	6.728	-3.456	3.468e-03	0.107	-1.746	CD59	CD59 molecule, complement regulatory protein	11	-33681131, -33681131, -33681131	AI653117	966	11p13	Hs.278573 Hs.709466 Hs.710641	107	protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane	Complement and coagulation cascades Hematopoietic cell lineage
226433_at	-1.034	7.026	-3.456	3.468e-03	0.107	-1.746	RNF157	ring finger protein 157	17	-71650128	BF056204	114804	17q25.1	Hs.500643	3	protein binding zinc ion binding metal ion binding
230195_at	1.327	10.927	3.455	3.476e-03	0.107	-1.748	LOC100131138	similar to hCG2040918	12		BF672169	100131138	12q24.11	Hs.152129
218642_s_at	0.430	7.636	3.454	3.481e-03	0.107	-1.750	CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7	8	57286868	NM_024300	79145	8q12.1	Hs.436913	9
218918_at	0.353	5.636	3.452	3.492e-03	0.107	-1.753	MAN1C1	mannosidase, alpha, class 1C, member 1	1	25816545	NM_020379	57134	1p35	Hs.197043	26	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding Golgi apparatus protein amino acid N-linked glycosylation metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds integral to Golgi membrane	N-Glycan biosynthesis Metabolic pathways
200071_at	-0.624	8.339	-3.452	3.496e-03	0.107	-1.754	SMNDC1	survival motor neuron domain containing 1	10	-112042787	BF224259	10285	10q23	Hs.632093	12	spliceosome assembly RNA binding protein binding nucleus spliceosomal complex cytoplasm mRNA processing apoptosis induction of apoptosis RNA splicing Cajal body nuclear speck RNA splicing factor activity, transesterification mechanism
205988_at	0.319	4.907	3.450	3.506e-03	0.107	-1.756	CD84	CD84 molecule	1	-158782410	NM_003874	8832	1q24	Hs.398093	23	receptor activity protein binding plasma membrane integral to plasma membrane defense response cell adhesion homophilic cell adhesion
236302_at	2.375	3.500	3.449	3.516e-03	0.108	-1.759	PPM1E	protein phosphatase 1E (PP2C domain containing)	17	54188230	R40892	22843	17q22	Hs.245044	5	magnesium ion binding protein serine/threonine phosphatase activity nucleus nucleolus cytoplasm protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity manganese ion binding
201931_at	0.378	10.721	3.449	3.519e-03	0.108	-1.760	ETFA	electron-transfer-flavoprotein, alpha polypeptide	15	-74295683	NM_000126	2108	15q23-q25	Hs.39925	18	mitochondrion mitochondrial matrix transport electron carrier activity oxidoreductase activity electron transport chain FAD binding
211985_s_at	-0.519	10.126	-3.449	3.520e-03	0.108	-1.760	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	AI653730	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
212118_at	0.316	6.819	3.447	3.529e-03	0.108	-1.762	TRIM27	tripartite motif-containing 27	6	-28978757, -330309, -128126	AL523814	5987	6p22	Hs.440382	27	negative regulation of transcription from RNA polymerase II promoter DNA binding transmembrane receptor protein tyrosine kinase activity protein binding intracellular membrane fraction nucleus nucleoplasm cytoplasm integral to plasma membrane spermatogenesis zinc ion binding cell proliferation nuclear membrane regulation of transcription negative regulation of gene expression, epigenetic metal ion binding protein trimerization
216973_s_at	0.536	5.099	3.446	3.536e-03	0.108	-1.764	HOXB7	homeobox B7	17	-44039593	S49765	3217	17q21.3	Hs.436181	39	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation myeloid cell differentiation sequence-specific DNA binding embryonic skeletal system morphogenesis
239192_at	0.299	3.399	3.446	3.539e-03	0.108	-1.765	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	2	205118760	BF434006	117583	2q33.3	Hs.657382	11	protein binding tight junction cell cycle membrane cell junction cell division
201124_at	0.366	5.461	3.445	3.546e-03	0.108	-1.767	ITGB5	integrin, beta 5	3	-125964484	AL048423	3693	3q21.2	Hs.536663	55	receptor activity protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
219468_s_at	-0.494	6.081	-3.444	3.550e-03	0.108	-1.768	CUEDC1	CUE domain containing 1	17	-53295335	NM_017949	404093	17q23.2	Hs.46679	4
227498_at	-1.034	7.987	-3.444	3.551e-03	0.108	-1.768	SOX6	SRY (sex determining region Y)-box 6	11	-15944571, -15944571, -15944571	AI480314	55553	11p15.3	Hs.368226	24	transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent multicellular organismal development muscle organ development
218706_s_at	0.714	5.188	3.444	3.555e-03	0.108	-1.769	GRAMD3	GRAM domain containing 3	5	125723686, 125786767, 125828685	AW575493	65983	5q23.2	Hs.363558	6
1562484_at	-0.552	3.393	-3.444	3.555e-03	0.108	-1.769	FLJ35848	hypothetical protein FLJ35848	17	40089507	BC041481	284071	17q21.31	Hs.349758	2
214937_x_at	-0.433	8.865	-3.443	3.557e-03	0.108	-1.770	PCM1	pericentriolar material 1	8	17824645	AI924817	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
1569171_a_at	0.310	4.857	3.443	3.558e-03	0.108	-1.770	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	BC034416	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
1567014_s_at	-0.475	5.957	-3.443	3.564e-03	0.108	-1.771	NFE2L2	nuclear factor (erythroid-derived 2)-like 2	2	-177803279, -177803278	AF323119	4780	2q31	Hs.715540	141	transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity
219263_at	-0.686	6.831	-3.442	3.569e-03	0.108	-1.773	RNF128	ring finger protein 128	X	105823723, 105856549	NM_024539	79589	Xq22.3	Hs.496542	13	protein binding cytoplasm zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding perinuclear region of cytoplasm
203855_at	-0.728	8.107	-3.441	3.573e-03	0.108	-1.774	WDR47	WD repeat domain 47	1	-109314359	NM_014969	22911	1p13.3	Hs.654760	8
202234_s_at	-0.648	7.965	-3.441	3.577e-03	0.108	-1.775	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	BF511091	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
242648_at	-0.603	7.952	-3.440	3.578e-03	0.108	-1.775	KLHL8	kelch-like 8 (Drosophila)	4	-88301237	BE858995	57563	4q22.1	Hs.106601 Hs.715202	9	protein binding
222472_at	-0.487	6.899	-3.440	3.582e-03	0.108	-1.776	AFTPH	aftiphilin	2	64604968	BF055271	54812	2p14	Hs.655167	12	cytoplasm cytosol protein transport AP-1 adaptor complex clathrin binding
201957_at	-0.478	8.875	-3.439	3.586e-03	0.108	-1.777	PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B	1	200584458, 200698493	AF324888	4660	1q32.1	Hs.444403	14	cytoplasm regulation of muscle contraction signal transduction enzyme activator activity	Vascular smooth muscle contraction
209163_at	0.480	4.914	3.439	3.588e-03	0.108	-1.778	CYB561	cytochrome b-561	17	-58863396, -58863396, -58863396	AL514271	1534	17q11-qter	Hs.355264	12	ferric-chelate reductase activity cytochrome-b5 reductase activity iron ion binding nucleolus plasma membrane integral to plasma membrane transport electron transport chain metal ion binding
232004_at	-0.463	6.054	-3.439	3.592e-03	0.108	-1.779	HNRNPR	heterogeneous nuclear ribonucleoprotein R	1	-23508862	AK001846	10236	1p36.12	Hs.373763	17	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex RNA splicing heterogeneous nuclear ribonucleoprotein complex
203471_s_at	0.455	4.429	3.437	3.604e-03	0.109	-1.782	PLEK	pleckstrin	2	68445825	NM_002664	5341	2p14-p13.3	Hs.468840	23	hemopoietic progenitor cell differentiation protein kinase C binding protein binding membrane fraction soluble fraction cytoplasm vesicle docking during exocytosis integrin-mediated signaling pathway intracellular signaling cascade positive regulation of platelet activation negative regulation of inositol phosphate biosynthetic process positive regulation of inositol-polyphosphate 5-phosphatase activity phosphoinositide metabolic process positive regulation of actin filament depolymerization inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway cortical actin cytoskeleton organization ruffle organization actin cytoskeleton reorganization positive regulation of actin filament bundle formation ruffle membrane positive regulation of integrin activation protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding negative regulation of calcium-mediated signaling regulation of cell diameter thrombin receptor signaling pathway platelet aggregation protein kinase C signaling cascade protein secretion by platelet
225639_at	0.870	6.745	3.437	3.606e-03	0.109	-1.782	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	N21390	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
220018_at	-0.718	4.402	-3.436	3.612e-03	0.109	-1.784	CBLL1	Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1	7	107171514	NM_024814	79872	7q22.3-q31.1	Hs.592271	9	protein binding intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
201162_at	0.763	9.979	3.435	3.620e-03	0.109	-1.786	IGFBP7	insulin-like growth factor binding protein 7	4	-57592000	NM_001553	3490	4q12	Hs.479808 Hs.711065	39	regulation of cell growth insulin-like growth factor binding extracellular region cell adhesion negative regulation of cell proliferation
203863_at	-0.700	11.034	-3.434	3.626e-03	0.109	-1.787	ACTN2	actinin, alpha 2	1	234916392	W63731	88	1q42-q43	Hs.498178	57	actin binding integrin binding calcium ion binding nucleolus cytoplasm cytoskeleton actin filament focal adhesion muscle contraction cell adhesion structural constituent of muscle Z disc microspike assembly filopodium thyroid hormone receptor coactivator activity pseudopodium titin binding identical protein binding regulation of apoptosis dendritic spine protein dimerization activity focal adhesion formation protein homotetramerization ZASP binding FATZ 1 binding titin Z domain binding	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
229327_s_at	-0.852	7.139	-3.434	3.626e-03	0.109	-1.788	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	16	-78185246	BE674528	4094	16q22-q23	Hs.134859	37	chromatin cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of chondrocyte differentiation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cell development lens fiber cell differentiation
206377_at	0.427	3.734	3.433	3.636e-03	0.109	-1.790	FOXF2	forkhead box F2	6	1335067	NM_001452	2295	6p25.3	Hs.484423	7	transcription factor activity protein binding nucleus transcription factor complex transcription activator activity extracellular matrix organization establishment of polarity of embryonic epithelium sequence-specific DNA binding negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent embryonic gut development
206158_s_at	-0.416	11.893	-3.431	3.646e-03	0.109	-1.792	CNBP	CCHC-type zinc finger, nucleic acid binding protein	3	-130369347	NM_003418	7555	3q21	Hs.518249	24	transcription factor activity protein binding cytoplasm endoplasmic reticulum regulation of transcription, DNA-dependent cholesterol biosynthetic process zinc ion binding metal ion binding
225429_at	-0.761	8.456	-3.430	3.653e-03	0.110	-1.794	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	BF437011	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
222825_at	-0.702	6.919	-3.430	3.654e-03	0.110	-1.795	OTUD6B	OTU domain containing 6B	8	92151599	BF435752	51633	8q21.3	Hs.30532	4
204117_at	-0.397	8.773	-3.430	3.658e-03	0.110	-1.796	PREP	prolyl endopeptidase	6	-105832198	NM_002726	5550	6q22	Hs.436564	26	serine-type endopeptidase activity cytoplasm proteolysis peptidase activity
205591_at	-0.466	6.013	-3.429	3.661e-03	0.110	-1.796	OLFM1	olfactomedin 1	9	137106909, 137106923	NM_006334	10439	9q34.3	Hs.522484	9	protein binding endoplasmic reticulum endoplasmic reticulum lumen multicellular organismal development nervous system development membrane
218788_s_at	0.482	6.379	3.429	3.663e-03	0.110	-1.797	SMYD3	SET and MYND domain containing 3	1	-243979266	NM_022743	64754	1q44	Hs.567571	18	protein binding nucleus cytoplasm methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
203706_s_at	-0.899	7.914	-3.428	3.669e-03	0.110	-1.798	FZD7	frizzled homolog 7 (Drosophila)	2	202607554	NM_003507	8324	2q33	Hs.173859	23	non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway multicellular organismal development integral to membrane Wnt receptor signaling pathway Wnt receptor activity	Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma
226968_at	-0.494	10.187	-3.428	3.670e-03	0.110	-1.799	KIF1B	kinesin family member 1B	1	10193350, 10193350	AK023184	23095	1p36.2	Hs.97858	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle
225733_at	0.302	5.786	3.428	3.670e-03	0.110	-1.799	B3GALT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6	1	1157491	AI890557	126792	1p36.33	Hs.284284	4	Golgi apparatus Golgi medial cisterna glycosaminoglycan biosynthetic process protein amino acid glycosylation UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding galactosylxylosylprotein 3-beta-galactosyltransferase activity	Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways
238454_at	0.769	4.467	3.428	3.672e-03	0.110	-1.799	ZNF540	zinc finger protein 540	19	42734147	AA013398	163255	19q13.12	Hs.121283	5	DNA binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202462_s_at	-0.401	8.113	-3.427	3.683e-03	0.110	-1.802	DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	5	134122359	NM_014829	9879	5q31.1	Hs.406549	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing Cajal body nuclear speck hydrolase activity
200056_s_at	-0.557	8.583	-3.426	3.684e-03	0.110	-1.802	C1D	C1D nuclear receptor co-repressor	2	-68122835	NM_006333	10438	2p13-p12	Hs.602900 Hs.697447	12	exosome (RNase complex) DNA binding transcription corepressor activity RNA binding protein binding nucleus nucleolus cytoplasm rRNA processing apoptosis negative regulation of transcription ligand-dependent nuclear receptor binding transcriptional repressor complex	RNA degradation
203920_at	0.447	5.158	3.426	3.687e-03	0.110	-1.803	NR1H3	nuclear receptor subfamily 1, group H, member 3	11	47227024, 47236072	NM_005693	10062	11p11.2	Hs.438863 Hs.513522	94	transcription factor activity steroid hormone receptor activity transcription coactivator activity thyroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding positive regulation of specific transcription from RNA polymerase II promoter negative regulation of foam cell differentiation positive regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux negative regulation of cholesterol storage positive regulation of cellular protein metabolic process negative regulation of lipid transport sequence-specific DNA binding positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of pinocytosis positive regulation of lipoprotein lipase activity	PPAR signaling pathway
208317_at	0.292	2.261	3.426	3.690e-03	0.110	-1.804	XYLB	xylulokinase homolog (H. influenzae)	3	38363254	NM_005108	9942	3p22-p21.3	Hs.659985	4	nucleotide binding xylulokinase activity ATP binding carbohydrate metabolic process generation of precursor metabolites and energy kinase activity transferase activity D-xylose metabolic process	Pentose and glucuronate interconversions Metabolic pathways
218756_s_at	0.635	6.561	3.426	3.690e-03	0.110	-1.804	DHRS11	dehydrogenase/reductase (SDR family) member 11	17	32022338	NM_024308	79154	17q12	Hs.462859	5	binding extracellular region oxidoreductase activity oxidation reduction
227822_at	0.485	6.406	3.425	3.694e-03	0.110	-1.805	ZNF605	zinc finger protein 605	12	-132008119	AI341321	90462	12q24.33	Hs.29698	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214921_at	0.410	3.365	3.425	3.697e-03	0.110	-1.805	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	10	-78314641, -78299364	U02632	3778	10q22.3	Hs.144795	89	magnesium ion binding response to hypoxia actin binding catalytic activity voltage-gated ion channel activity voltage-gated potassium channel activity calcium ion binding protein binding caveola ion transport potassium ion transport response to osmotic stress synaptic transmission sensory perception of sound circadian rhythm adult walking behavior voltage-gated potassium channel complex metabolic process external side of plasma membrane integral to membrane apical plasma membrane regulation of action potential in neuron cellular potassium ion homeostasis potassium ion binding regulation of aldosterone metabolic process response to carbon monoxide response to carbon monoxide regulation of membrane potential auditory receptor cell differentiation positive regulation of apoptosis terminal button postsynaptic membrane locomotor rhythm negative regulation of cell volume saliva secretion cell maturation neuromuscular process controlling balance response to calcium ion large conductance calcium-activated potassium channel activity eye blink reflex smooth muscle contraction involved in micturition relaxation of vascular smooth muscle	Vascular smooth muscle contraction
225819_at	-0.468	5.926	-3.424	3.701e-03	0.110	-1.806	TBRG1	transforming growth factor beta regulator 1	11	123997951	AA576946	84897	11q24.2	Hs.436410	11	DNA binding protein binding nucleus DNA replication cell cycle cell cycle arrest negative regulation of cell proliferation nucleolus to nucleoplasm transport protein stabilization
203405_at	-0.495	6.521	-3.423	3.710e-03	0.110	-1.809	PSMG1	proteasome (prosome, macropain) assembly chaperone 1	21	-39469253	NM_003720	8624	21q22.3	Hs.473838	12	protein binding cytoplasm endoplasmic reticulum proteasome assembly
209568_s_at	0.524	6.717	3.423	3.712e-03	0.110	-1.809	RGL1	ral guanine nucleotide dissociation stimulator-like 1	1	181871830	AF186779	23179	1q25.3	Hs.497148	6	guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular signal transduction Ral guanyl-nucleotide exchange factor activity regulation of small GTPase mediated signal transduction
203476_at	0.489	6.002	3.422	3.716e-03	0.110	-1.810	TPBG	trophoblast glycoprotein	6	83130257	NM_006670	7162	6q14-q15	Hs.82128	16	protein binding cytoplasm endoplasmic reticulum integral to plasma membrane cell adhesion membrane
202718_at	0.640	5.719	3.422	3.720e-03	0.110	-1.811	IGFBP2	insulin-like growth factor binding protein 2, 36kDa	2	217206371	NM_000597	3485	2q33-q34	Hs.438102	95	regulation of cell growth extracellular region extracellular space signal transduction insulin-like growth factor I binding insulin-like growth factor II binding regulation of insulin-like growth factor receptor signaling pathway regulation of insulin-like growth factor receptor signaling pathway
213664_at	0.553	5.020	3.421	3.722e-03	0.110	-1.812	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	9	4480443	AW235061	6505	9p24	Hs.444915	43	L-glutamate transmembrane transporter activity membrane fraction integral to plasma membrane transport dicarboxylic acid transport synaptic transmission symporter activity membrane sodium:dicarboxylate symporter activity L-glutamate import D-aspartate import
215559_at	-1.118	5.747	-3.421	3.723e-03	0.110	-1.812	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	16	-16222544, -16150922	AI074459	368	16p13.1	Hs.442182	70	nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus	ABC transporters
217880_at	-0.443	6.727	-3.421	3.725e-03	0.110	-1.812	CDC27	cell division cycle 27 homolog (S. cerevisiae)	17	-42550309	N21397	996	17q12-q23.2	Hs.463295	53	protein binding nucleus nucleoplasm cytoplasm centrosome cytosol spindle microtubule mitotic metaphase/anaphase transition cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
226874_at	-0.619	7.650	-3.421	3.726e-03	0.110	-1.813	KLHL8	kelch-like 8 (Drosophila)	4	-88301237	BF591270	57563	4q22.1	Hs.106601 Hs.715202	9	protein binding
231260_at	0.404	3.911	3.421	3.729e-03	0.110	-1.813	BC036928	hypothetical protein BC036928	19		AW162207	386758	19q13.43	Hs.549564	1
226515_at	-0.417	8.030	-3.419	3.743e-03	0.111	-1.817	CCDC127	coiled-coil domain containing 127	5	-257874	AL577758	133957	5p15.33	Hs.294145	4
213026_at	-0.378	7.658	-3.417	3.753e-03	0.111	-1.819	ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	5	-115193714	BE965998	9140	5q21-q22	Hs.264482	17	autophagic vacuole formation protein binding cytoplasm autophagy modification-dependent protein catabolic process pre-autophagosomal structure membrane intracellular membrane-bounded organelle	Regulation of autophagy RIG-I-like receptor signaling pathway
235907_at	-0.310	4.953	-3.417	3.755e-03	0.111	-1.820	TMEM33	transmembrane protein 33	4	41631893	BE245080	55161	4p13	Hs.31082	5	protein binding biological_process membrane integral to membrane melanosome
230029_x_at	-0.478	11.072	-3.417	3.756e-03	0.111	-1.820	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	2	170392263	AI708334	130507	2q31.1	Hs.379548	7	suckling behavior ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process sensory perception of smell zinc ion binding embryonic development membrane integral to membrane ligase activity metal ion binding
202098_s_at	0.383	6.417	3.416	3.765e-03	0.111	-1.822	PRMT2	protein arginine methyltransferase 2	21	46879954	NM_001535	3275	21q22.3	Hs.154163	17	signal transducer activity nucleus protein amino acid methylation signal transduction methyltransferase activity transferase activity identical protein binding
218577_at	-0.448	7.135	-3.416	3.767e-03	0.111	-1.823	LRRC40	leucine rich repeat containing 40	1	-70383084	NM_017768	55631	1p31.1	Hs.147836	6	protein binding
1569348_at	-0.571	4.238	-3.415	3.773e-03	0.111	-1.824	psiTPTE22	TPTE pseudogene	22	15462800	BC017420	387590	22q11.1	Hs.474116	4
206256_at	-0.266	4.596	-3.414	3.778e-03	0.111	-1.826	CPN1	carboxypeptidase N, polypeptide 1	10	-101792054	NM_001308	1369	10q24.2	Hs.2246	16	metallocarboxypeptidase activity extracellular region extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
208076_at	0.361	3.011	3.414	3.778e-03	0.111	-1.826	HIST1H4D	histone cluster 1, H4d	6	-26296916	NM_003539	8360	6p21.3	Hs.248179	10		Systemic lupus erythematosus
45714_at	-1.078	9.104	-3.414	3.779e-03	0.111	-1.826	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)	16	-3012626	AA436930	54985	16p13.3	Hs.719259	2	nucleus cytoplasm
213819_s_at	-0.271	5.071	-3.414	3.780e-03	0.111	-1.826	FLOT1	flotillin 1	6	-30803489, -2144083, -1942389	H45696	10211	6p21.3	Hs.179986	36	protein binding Golgi apparatus microtubule organizing center plasma membrane integral to membrane flotillin complex centriolar satellite melanosome	Insulin signaling pathway
202749_at	-0.539	8.821	-3.414	3.781e-03	0.111	-1.826	WRB	tryptophan rich basic protein	21	39674082, 39681561	NM_004627	7485	21q22.3	Hs.198308	7	nucleus nucleolus membrane integral to membrane
221889_at	0.321	4.909	3.413	3.789e-03	0.111	-1.828	KCTD13	potassium channel tetramerisation domain containing 13	16	-29825161	AW026481	253980	16p11.2	Hs.534590	9	voltage-gated potassium channel activity nucleus DNA replication potassium ion transport voltage-gated potassium channel complex membrane identical protein binding
201135_at	0.429	10.281	3.413	3.789e-03	0.111	-1.828	ECHS1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	10	-135025976	NM_004092	1892	10q26.2-q26.3	Hs.76394	16	enoyl-CoA hydratase activity enoyl-CoA hydratase activity protein binding mitochondrion mitochondrial matrix mitochondrial matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process lyase activity	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Metabolic pathways
203312_x_at	-0.465	6.797	-3.412	3.793e-03	0.111	-1.829	ARF6	ADP-ribosylation factor 6	14	49429485	NM_001663	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
211755_s_at	0.386	12.136	3.412	3.797e-03	0.111	-1.830	ATP5F1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1	1	111793265	BC005960	515	1p13.2	Hs.514870	15	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) transporter activity protein binding mitochondrion mitochondrial matrix ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1568644_at	0.293	2.618	3.411	3.801e-03	0.111	-1.831	ZNF208	zinc finger protein 208	19	-21940736	BC038199	7757	19p12	Hs.541334	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
228967_at	-0.874	8.160	-3.411	3.801e-03	0.111	-1.831	EIF1	eukaryotic translation initiation factor 1	17	37098652	BE964053	10209	17q21.2	Hs.150580	10	translation initiation factor activity cytoplasm regulation of translational initiation response to stress
231530_s_at	0.748	6.457	3.411	3.803e-03	0.111	-1.832	C11orf1	chromosome 11 open reading frame 1	11	111255157	BG150085	64776	11q13-q22	Hs.17546	5	molecular_function nucleus biological_process
218311_at	-0.523	7.417	-3.411	3.805e-03	0.111	-1.832	MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	2	-39329925	NM_003618	8491	2p22.1	Hs.655750	7	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade transferase activity	MAPK signaling pathway
219213_at	0.461	6.066	3.409	3.815e-03	0.111	-1.834	JAM2	junctional adhesion molecule 2	21	25933459	NM_021219	58494	21q21.2	Hs.517227	21	plasma membrane plasma membrane integral to plasma membrane tight junction cell-cell adhesion cell junction	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
202842_s_at	-0.450	8.301	-3.409	3.818e-03	0.111	-1.835	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	AL080081	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
221087_s_at	0.473	6.180	3.409	3.818e-03	0.111	-1.835	APOL3	apolipoprotein L, 3	22	-34866317, -34866317	NM_014349	80833	22q13.1	Hs.474737	11	signal transducer activity lipid transporter activity extracellular region cytoplasm lipid transport inflammatory response lipid binding lipoprotein metabolic process positive regulation of I-kappaB kinase/NF-kappaB cascade
206695_x_at	0.651	3.798	3.409	3.822e-03	0.111	-1.836	ZNF43	zinc finger protein 43	19	-21779591	NM_003423	7594	19p13.1-p12	Hs.534365	13	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1558041_a_at	0.354	5.030	3.408	3.824e-03	0.111	-1.837	KIAA0895L	KIAA0895-like	16	-65767005	AL834156	653319	16q22.1	Hs.651201	2
229614_at	0.514	4.892	3.408	3.826e-03	0.111	-1.837	ZNF320	zinc finger protein 320	19	-58071236	AI277652	162967	19q13.41	Hs.446907	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
200941_at	-0.454	7.861	-3.407	3.834e-03	0.111	-1.839	HSBP1	heat shock factor binding protein 1	16	82399093	AK026575	3281	16q23.3	Hs.250899 Hs.705549	8	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus
219072_at	0.334	7.336	3.407	3.835e-03	0.111	-1.839	BCL7C	B-cell CLL/lymphoma 7C	16	-30806616	NM_004765	9274	16p11	Hs.658547	9	apoptosis
217403_s_at	0.333	3.202	3.404	3.855e-03	0.112	-1.844	ZNF227	zinc finger protein 227	19	49408530	AC074331	7770		Hs.371335	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203912_s_at	-0.440	9.011	-3.403	3.867e-03	0.112	-1.847	DNASE1L1	deoxyribonuclease I-like 1	X	-153282772, -153282772	NM_006730	1774	Xq28	Hs.401929	14	DNA binding endonuclease activity deoxyribonuclease activity endoplasmic reticulum DNA catabolic process hydrolase activity
1563483_at	-0.530	4.036	-3.402	3.871e-03	0.112	-1.848	FAM91A2	family with sequence similarity 91, member A2	1		AB007962	57234	1q21.1	Hs.710717	3
229539_at	0.297	5.420	3.402	3.874e-03	0.112	-1.849	ABCB8	ATP-binding cassette, sub-family B (MDR/TAP), member 8	7	150356442	AW665395	11194	7q36	Hs.647118	12	nucleotide binding transporter activity ATP binding membrane fraction mitochondrion mitochondrial envelope mitochondrial inner membrane transport membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters
201040_at	0.419	6.118	3.402	3.875e-03	0.112	-1.849	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	3	50248650	NM_002070	2771	3p21	Hs.77269	85	nucleotide binding activation of MAPKK activity adenosine receptor signaling pathway GTPase activity signal transducer activity protein binding GTP binding membrane fraction nucleus cytosol plasma membrane signal transduction inhibition of adenylate cyclase activity by G-protein signaling muscarinic acetylcholine receptor signaling pathway gamma-aminobutyric acid signaling pathway protein kinase cascade response to nutrient positive regulation of cell proliferation guanyl nucleotide binding membrane raft negative regulation of synaptic transmission negative regulation of calcium ion transport via voltage-gated calcium channel activity	Chemokine signaling pathway Axon guidance Tight junction Gap junction Leukocyte transendothelial migration Long-term depression Melanogenesis
224677_x_at	-0.311	8.682	-3.401	3.879e-03	0.112	-1.850	C11orf31	chromosome 11 open reading frame 31	11	57265297	AV729234	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
244655_at	0.552	4.113	3.401	3.879e-03	0.112	-1.850	LOC100132798	similar to hCG1774772	15		W68045	100132798	15q26.2
1558759_s_at	-0.549	5.702	-3.401	3.879e-03	0.112	-1.850	CLASP2	cytoplasmic linker associated protein 2	3	-33512741	AA310888	23122	3p22.3	Hs.108614	17	condensed chromosome kinetochore protein binding cytoplasm Golgi apparatus centrosome spindle kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity galactoside 2-alpha-L-fucosyltransferase activity regulation of microtubule polymerization or depolymerization microtubule plus-end binding cell division
205450_at	-0.956	8.175	-3.401	3.883e-03	0.112	-1.851	PHKA1	phosphorylase kinase, alpha 1 (muscle)	X	-71715388	NM_002637	5255	Xq12-q13	Hs.201379	12	catalytic activity phosphorylase kinase activity calmodulin binding cytoplasm plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy intracellular membrane-bounded organelle	Calcium signaling pathway Insulin signaling pathway
201701_s_at	-0.564	6.694	-3.401	3.886e-03	0.112	-1.852	PGRMC2	progesterone receptor membrane component 2	4	-129410746	NM_006320	10424	4q26	Hs.507910	9	steroid hormone receptor activity receptor activity steroid binding protein binding membrane integral to membrane heme binding
217788_s_at	-0.432	8.078	-3.400	3.892e-03	0.112	-1.853	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	1	228269578	NM_004481	2590	1q41-q42	Hs.716384	24	immunoglobulin biosynthetic process polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus Golgi stack membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding integral to Golgi membrane perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
222785_x_at	0.838	6.359	3.399	3.902e-03	0.112	-1.855	C11orf1	chromosome 11 open reading frame 1	11	111255157	AJ250229	64776	11q13-q22	Hs.17546	5	molecular_function nucleus biological_process
235604_x_at	0.538	4.708	3.398	3.907e-03	0.112	-1.856	ZNF493	zinc finger protein 493	19	21371760, 21371760	AI758697	284443	19p12	Hs.656558	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
214209_s_at	0.315	4.153	3.398	3.910e-03	0.113	-1.857	ABCB9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	12	-121979491, -121979491	BE504895	23457	12q24	Hs.511951	20	nucleotide binding transporter activity ATP binding lysosome endoplasmic reticulum spermatogenesis protein transport peptide transport membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex	ABC transporters Lysosome
221926_s_at	0.387	5.445	3.395	3.930e-03	0.113	-1.862	IL17RC	interleukin 17 receptor C	3	9933763	BF196320	84818	3p25.3 3p25.3-p24.1	Hs.129959	14	receptor activity plasma membrane integral to membrane
213380_x_at	0.333	5.443	3.394	3.937e-03	0.113	-1.864	MSTP9	macrophage stimulating, pseudogene 9	1	-16953988	AA911235	11223	1p36.13	Hs.349110 Hs.655432	2	serine-type endopeptidase activity extracellular region proteolysis peptidase activity
222405_at	0.260	6.985	3.394	3.938e-03	0.113	-1.864	PTPLAD1	protein tyrosine phosphatase-like A domain containing 1	15	63609879	AL573951	51495	15q22.2	Hs.512973	13	molecular_function GTPase activator activity protein binding cellular_component I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity small GTPase mediated signal transduction Rho protein signal transduction membrane integral to membrane Rac protein signal transduction
AFFX-HUMGAPDH/M33197_3_at	-0.268	13.587	-3.391	3.960e-03	0.114	-1.869	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	AFFX-HUMGAPDH/M33197_3	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
208924_at	-0.403	9.892	-3.391	3.964e-03	0.114	-1.870	RNF11	ring finger protein 11	1	51474532	AB024703	26994	1pter-p22.1	Hs.309641	17	ubiquitin ligase complex DNA binding protein binding nucleus cytoplasm zinc ion binding protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
226541_at	-0.448	6.966	-3.390	3.968e-03	0.114	-1.871	FBXO30	F-box protein 30	6	-146160964	AI808182	84085	6q24	Hs.421095	8	zinc ion binding modification-dependent protein catabolic process metal ion binding
228622_s_at	0.358	7.183	3.390	3.973e-03	0.114	-1.872	DNAJC4	DnaJ (Hsp40) homolog, subfamily C, member 4	11	63754328	AW071239	3338	11q13	Hs.172847	4	membrane fraction protein folding response to unfolded protein membrane integral to membrane heat shock protein binding unfolded protein binding
213181_s_at	0.398	5.203	3.389	3.976e-03	0.114	-1.873	MOCS1	molybdenum cofactor synthesis 1	6	-39980023, -39980023	AL583528	4337	6p21.3	Hs.718492	19	nucleotide binding catalytic activity iron ion binding GTP binding nucleus Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor biosynthetic process metabolic process molybdopterin synthase complex molybdenum ion binding metal ion binding 4 iron, 4 sulfur cluster binding
227874_at	0.491	7.601	3.389	3.980e-03	0.114	-1.874	EMCN	endomucin	4	-101535522	AI635774	51705	4q24	Hs.152913	12	extracellular region plasma membrane integral to membrane
211966_at	0.550	5.799	3.389	3.983e-03	0.114	-1.874	COL4A2	collagen, type IV, alpha 2	13	109757631	AA909035	1284	13q34	Hs.508716	54	extracellular matrix structural constituent binding extracellular region collagen collagen type IV negative regulation of angiogenesis extracellular matrix organization	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
215000_s_at	-0.709	9.974	-3.388	3.988e-03	0.114	-1.875	FEZ2	fasciculation and elongation protein zeta 2 (zygin II)	2	-36632904	AL117593	9637	2p21	Hs.258563	9	protein binding signal transduction nervous system development axon guidance
219866_at	-0.658	9.310	-3.388	3.988e-03	0.114	-1.876	CLIC5	chloride intracellular channel 5	6	-45974165, -45974165	NM_016929	53405	6p21.1-p12.1	Hs.485489	15	voltage-gated ion channel activity voltage-gated chloride channel activity protein binding insoluble fraction cytoplasm Golgi apparatus centrosome cell cortex ion transport chloride transport female pregnancy actin cytoskeleton membrane integral to membrane chloride ion binding chloride channel complex
1552316_a_at	0.595	5.203	3.387	3.996e-03	0.114	-1.877	GIMAP1	GTPase, IMAP family member 1	7	150044630	NM_130759	170575	7q36.1	Hs.647087	7	GTP binding endoplasmic reticulum membrane integral to membrane
222963_s_at	0.415	4.017	3.387	3.998e-03	0.114	-1.878	IL1RAPL1	interleukin 1 receptor accessory protein-like 1	X	28515601	AF284435	11141	Xp22.1-p21.3	Hs.658912	18	transmembrane receptor activity signal transduction learning or memory membrane integral to membrane innate immune response
202038_at	-0.465	8.304	-3.387	3.998e-03	0.114	-1.878	UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)	11	117735511	NM_004788	9354	11q23.3	Hs.602967 Hs.75275	12	ubiquitin ligase complex protein polyubiquitination protein binding cytoplasm ubiquitin-dependent protein catabolic process ubiquitin-ubiquitin ligase activity	Ubiquitin mediated proteolysis
1568718_at	-0.348	5.908	-3.387	4.000e-03	0.114	-1.878	SLC22A23	solute carrier family 22, member 23	6	-3214206, -3214206	BC038748	63027	6p25.2	Hs.713588	7	transporter activity ion transport membrane integral to membrane
204204_at	-0.584	6.238	-3.386	4.006e-03	0.114	-1.880	SLC31A2	solute carrier family 31 (copper transporters), member 2	9	114953058	NM_001860	1318	9q31-q32	Hs.24030	7	copper ion transmembrane transporter activity copper ion binding integral to plasma membrane ion transport copper ion transport membrane
200748_s_at	0.464	12.251	3.385	4.009e-03	0.114	-1.880	FTH1	ferritin, heavy polypeptide 1	11	-61488332	NM_002032	2495	11q13	Hs.524910 Hs.645560	55	ferroxidase activity protein binding iron ion transport intracellular sequestering of iron ion immune response intracellular ferritin complex ferric iron binding negative regulation of cell proliferation oxidoreductase activity oxidation reduction	Porphyrin and chlorophyll metabolism
204071_s_at	-0.647	6.440	-3.385	4.011e-03	0.114	-1.881	TOPORS	topoisomerase I binding, arginine/serine-rich	9	-32530541	NM_005802	10210	9p21	Hs.589962 Hs.711159	30	DNA binding antigen binding protein binding nucleus apoptosis response to DNA damage stimulus visual perception zinc ion binding nuclear speck ligase activity DNA topoisomerase I binding modification-dependent protein catabolic process regulation of cell proliferation positive regulation of transcription metal ion binding response to stimulus maintenance of protein location in nucleus
212875_s_at	0.407	5.785	3.384	4.020e-03	0.114	-1.883	C2CD2	C2 calcium-dependent domain containing 2	21	-42178287, -42178287	AP001745	25966	21q22.3	Hs.473894 Hs.675058	4	extracellular region nucleus cytosol
234982_at	-0.699	10.083	-3.383	4.026e-03	0.114	-1.884	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	2	170392263	BF577193	130507	2q31.1	Hs.379548	7	suckling behavior ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process sensory perception of smell zinc ion binding embryonic development membrane integral to membrane ligase activity metal ion binding
219751_at	-0.478	5.538	-3.383	4.033e-03	0.114	-1.886	SETD6	SET domain containing 6	16	57106883	NM_024860	79918	16q21	Hs.592060	5
205986_at	0.339	5.830	3.382	4.034e-03	0.114	-1.886	AATK	apoptosis-associated tyrosine kinase	17	-76705690	NM_004920	9625	17q25.3	Hs.514575	15	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm mitochondrion protein amino acid phosphorylation membrane integral to membrane transferase activity perinuclear region of cytoplasm
218649_x_at	-0.666	8.146	-3.382	4.037e-03	0.114	-1.887	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	NM_004713	9147	14q22	Hs.655964	8	nucleus cytoplasm
203633_at	0.621	7.024	3.382	4.037e-03	0.114	-1.887	CPT1A	carnitine palmitoyltransferase 1A (liver)	11	-68278926, -68278663	BF001714	1374	11q13.1-q13.2	Hs.503043	32	carnitine O-palmitoyltransferase activity mitochondrion mitochondrial outer membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport acyltransferase activity membrane integral to membrane transferase activity	Fatty acid metabolism PPAR signaling pathway Adipocytokine signaling pathway
203721_s_at	-0.683	7.769	-3.381	4.045e-03	0.115	-1.889	UTP18	UTP18, small subunit (SSU) processome component, homolog (yeast)	17	46692895	NM_016001	51096	17q21.33	Hs.709327	11	nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing
1554863_s_at	-0.511	7.602	-3.381	4.048e-03	0.115	-1.889	DOK5	docking protein 5	20	52525672	BC008992	55816	20q13.2	Hs.656582	10	MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development
211747_s_at	-0.402	8.655	-3.380	4.051e-03	0.115	-1.890	LSM5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	7	-32491469, -32491469, -32491469	BC005938	23658	7p14.3	Hs.424908	13	RNA binding protein binding nucleus mRNA processing RNA splicing ribonucleoprotein complex	RNA degradation
204174_at	0.371	5.442	3.380	4.056e-03	0.115	-1.891	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	13	30207668	NM_001629	241	13q12	Hs.507658	73	nucleus endoplasmic reticulum enzyme activator activity membrane integral to membrane leukotriene biosynthetic process nuclear membrane protein N-terminus binding arachidonic acid binding protein homotrimerization
244180_at	0.343	5.480	3.380	4.058e-03	0.115	-1.892	ZNF793	zinc finger protein 793	19	42689680	AI039201	390927	19q13.12	Hs.568010	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218484_at	0.447	6.248	3.379	4.059e-03	0.115	-1.892	NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	12	-55914952	NM_020142	56901	12q13.3	Hs.75069	5		Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
223583_at	0.365	5.061	3.379	4.060e-03	0.115	-1.892	TNFAIP8L2	tumor necrosis factor, alpha-induced protein 8-like 2	1	149395728	AF271774	79626	1q21.3	Hs.709522	2	protein binding innate immune response
210170_at	-1.081	9.678	-3.377	4.079e-03	0.115	-1.896	PDLIM3	PDZ and LIM domain 3	4	-186659844	BC001017	27295	4q35	Hs.85862	12	nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding
218438_s_at	-0.504	7.314	-3.376	4.088e-03	0.115	-1.898	MED28	mediator complex subunit 28	4	17225370	NM_025205	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
214380_at	0.372	4.985	3.376	4.089e-03	0.115	-1.899	PRPF31	PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)	19	59310601	AI334332	26121	19q13.42	Hs.515598	44	assembly of spliceosomal tri-snRNP nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex RNA splicing Cajal body nuclear speck ribonucleoprotein binding U4/U6 x U5 tri-snRNP complex
207120_at	0.417	3.186	3.375	4.094e-03	0.115	-1.900	ZNF667	zinc finger protein 667	19	-61643017	NM_022103	63934	19q13.43	Hs.712574	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226025_at	-0.670	8.430	-3.375	4.096e-03	0.115	-1.900	ANKRD28	ankyrin repeat domain 28	3	-15683747	AV740426	23243	3p25.1	Hs.335239	10	protein binding nucleus nucleoplasm
200618_at	0.402	6.755	3.374	4.101e-03	0.115	-1.901	LASP1	LIM and SH3 protein 1	17	34279637	NM_006148	3927	17q11-q21.3	Hs.548018	22	SH3/SH2 adaptor activity protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell cortex ion transport zinc ion binding ion transmembrane transporter activity cortical actin cytoskeleton cortical cytoskeleton organization metal ion binding actin filament binding
200804_at	-0.421	9.253	-3.374	4.106e-03	0.115	-1.903	TMBIM6	transmembrane BAX inhibitor motif containing 6	12	48421559, 48421858	NM_003217	7009	12q12-q13	Hs.35052 Hs.708025	20	insoluble fraction nucleus endoplasmic reticulum integral to plasma membrane spermatogenesis membrane negative regulation of apoptosis
223681_s_at	-0.954	8.420	-3.373	4.112e-03	0.116	-1.904	INADL	InaD-like (Drosophila)	1	61980736	AB044807	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
203571_s_at	0.562	7.577	3.373	4.114e-03	0.116	-1.904	C10orf116	chromosome 10 open reading frame 116	10	88718167	NM_006829	10974	10q23.2	Hs.642660 Hs.714477	4	molecular_function cellular_component biological_process
222410_s_at	-0.519	8.633	-3.373	4.116e-03	0.116	-1.905	SNX6	sorting nexin 6	14	-34100368, -34100368	AF121856	58533	14q13.1	Hs.583855	7	protein binding intracellular cytoplasm intracellular protein transport cell communication negative regulation of epidermal growth factor receptor activity negative regulation of transcription negative regulation of transforming growth factor beta receptor signaling pathway phosphoinositide binding protein homodimerization activity
204446_s_at	0.433	3.702	3.372	4.118e-03	0.116	-1.905	ALOX5	arachidonate 5-lipoxygenase	10	45189634	NM_000698	240	10q11.2	Hs.89499	141	arachidonate 5-lipoxygenase activity iron ion binding calcium ion binding protein binding nucleus nuclear envelope lumen cytoplasm cytosol inflammatory response membrane lipoxygenase activity nuclear matrix oxidoreductase activity leukotriene biosynthetic process nuclear membrane oxidation reduction	Arachidonic acid metabolism Linoleic acid metabolism Metabolic pathways
210076_x_at	-0.331	9.140	-3.372	4.120e-03	0.116	-1.906	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	AF151813	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
210045_at	-0.434	8.326	-3.371	4.129e-03	0.116	-1.908	IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	15	-88428215	AU151428	3418	15q26.1	Hs.596461	20	magnesium ion binding isocitrate dehydrogenase (NADP+) activity mitochondrion carbohydrate metabolic process glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding NAD or NADH binding oxidation reduction	Citrate cycle (TCA cycle) Glutathione metabolism Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
222798_at	0.672	7.204	3.371	4.131e-03	0.116	-1.908	PTER	phosphotriesterase related	10	16518972	BF112019	9317	10p12	Hs.444321 Hs.716660	6	zinc ion binding catabolic process hydrolase activity, acting on ester bonds metal ion binding
227466_at	0.463	7.725	3.371	4.133e-03	0.116	-1.909	LOC285550	hypothetical protein LOC285550	4	15292449	BF108695	285550	4p15.32	Hs.399980 Hs.619367	3
216867_s_at	-0.422	5.932	-3.371	4.133e-03	0.116	-1.909	PDGFA	platelet-derived growth factor alpha polypeptide	7	-503424	X03795	5154	7p22	Hs.535898	79	cell activation platelet-derived growth factor receptor binding platelet-derived growth factor receptor binding collagen binding extracellular region extracellular region extracellular space cell-cell signaling growth factor activity embryonic development cell surface negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation regulation of smooth muscle cell migration membrane positive regulation of cell migration platelet dense granule lumen regulation of actin cytoskeleton organization wound healing protein homodimerization activity cell surface binding positive regulation of DNA replication protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding negative chemotaxis	MAPK signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Glioma Prostate cancer Melanoma
201649_at	0.507	6.531	3.370	4.139e-03	0.116	-1.910	UBE2L6	ubiquitin-conjugating enzyme E2L 6	11	-57075704, -57075704	NM_004223	9246	11q12	Hs.425777	19	ubiquitin-protein ligase activity protein binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
206342_x_at	-0.461	6.047	-3.370	4.140e-03	0.116	-1.910	IDS	iduronate 2-sulfatase	X	-148376566, -148368202	NM_006123	3423	Xq28	Hs.460960	73	iduronate-2-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
204661_at	0.440	5.109	3.369	4.144e-03	0.116	-1.911	CD52	CD52 molecule	1	26516997	NM_001803	1043	1p36	Hs.276770	27	membrane fraction plasma membrane integral to plasma membrane elevation of cytosolic calcium ion concentration anchored to membrane respiratory burst
234003_at	0.335	4.419	3.369	4.145e-03	0.116	-1.911	ENOX2	ecto-NOX disulfide-thiol exchanger 2	X	-129585037	AL133115	10495	Xq25-q26.2	Hs.171458	22	nucleotide binding nucleic acid binding copper ion binding extracellular region extracellular space nucleus cytoplasm cytosol cytoskeleton plasma membrane transport ultradian rhythm external side of plasma membrane protein disulfide oxidoreductase activity cell growth oxidoreductase activity electron transport chain regulation of growth
201686_x_at	-0.307	5.513	-3.369	4.151e-03	0.116	-1.913	API5	apoptosis inhibitor 5	11	43290080	AF229254	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
228746_s_at	-0.608	8.292	-3.369	4.151e-03	0.116	-1.913	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	AV646549	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
222423_at	-0.352	7.461	-3.368	4.158e-03	0.116	-1.914	NDFIP1	Nedd4 family interacting protein 1	5	141468507	H05010	80762	5q31.3	Hs.653510 Hs.9788	11	signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport
204294_at	0.371	7.196	3.368	4.160e-03	0.116	-1.915	AMT	aminomethyltransferase	3	-49429214	NM_000481	275	3p21.2-p21.1	Hs.102	17	aminomethyltransferase activity cytoplasm mitochondrion glycine catabolic process transaminase activity transferase activity	Glycine, serine and threonine metabolism One carbon pool by folate Nitrogen metabolism Metabolic pathways
235177_at	-0.694	5.384	-3.366	4.176e-03	0.116	-1.918	FAM119A	family with sequence similarity 119, member A	2	-208182083, -208182083	AI625022	151194	2q33.3	Hs.664764	2	membrane integral to membrane
215596_s_at	-0.485	7.886	-3.365	4.181e-03	0.116	-1.919	RNF160	ring finger protein 160	21	-29222336	AL163248	26046	21q22.11	Hs.288773	4	protein binding zinc ion binding metal ion binding
221898_at	-0.516	6.126	-3.364	4.188e-03	0.116	-1.921	PDPN	podoplanin	1	13782838, 13784553	AU154455	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
225069_at	-0.479	8.085	-3.364	4.191e-03	0.116	-1.922	PCYT1A	phosphate cytidylyltransferase 1, choline, alpha	3	-197449649	BF063382	5130	3q29	Hs.435767	15	choline-phosphate cytidylyltransferase activity soluble fraction cytoplasm endoplasmic reticulum membrane cytosol phosphatidylcholine biosynthetic process phospholipid biosynthetic process biosynthetic process response to abiotic stimulus membrane transferase activity nucleotidyltransferase activity glycogen granule	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
219144_at	-0.719	9.919	-3.363	4.196e-03	0.117	-1.923	DUSP26	dual specificity phosphatase 26 (putative)	8	-33568392	NM_024025	78986	8p12	Hs.8719	6	protein tyrosine phosphatase activity nucleus cytoplasm Golgi apparatus protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
202578_s_at	-0.416	6.202	-3.363	4.200e-03	0.117	-1.923	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A	16	68938324	NM_018332	55308	16q22.1	Hs.656037	5	nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport
202130_at	-0.361	9.842	-3.362	4.207e-03	0.117	-1.925	RIOK3	RIO kinase 3 (yeast)	18	19286784	AA725102	8780	18q11.2	Hs.445511 Hs.719109	9	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation chromosome segregation kinase activity transferase activity
218504_at	0.468	8.390	3.362	4.209e-03	0.117	-1.925	FAHD2A	fumarylacetoacetate hydrolase domain containing 2A	2	95432174	NM_016044	51011	2p24.3-p11.2	Hs.546387	4	magnesium ion binding calcium ion binding metabolic process hydrolase activity
205472_s_at	0.593	4.213	3.362	4.209e-03	0.117	-1.926	DACH1	dachshund homolog 1 (Drosophila)	13	-70910098	NM_004392	1602	13q22	Hs.129452	24	nucleotide binding transcription factor activity protein binding nucleus transcription factor complex cytoplasm multicellular organismal development regulation of transcription
204689_at	0.505	4.675	3.362	4.210e-03	0.117	-1.926	HHEX	hematopoietically expressed homeobox	10	94439660	NM_001529	3087	10q23.33	Hs.118651	86	liver development transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent mRNA export from nucleus cell cycle multicellular organismal development transcription factor binding eukaryotic initiation factor 4E binding organ morphogenesis anterior/posterior pattern formation positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter negative regulation of angiogenesis transcription repressor activity cell differentiation positive regulation of Wnt receptor signaling pathway thyroid gland development forebrain development negative regulation of vascular endothelial growth factor receptor signaling pathway embryonic heart tube development regulation of cell proliferation sequence-specific DNA binding	Maturity onset diabetes of the young
220721_at	0.320	4.428	3.360	4.227e-03	0.117	-1.929	ZNF614	zinc finger protein 614	19	-57208389	NM_025040	80110	19q13.41	Hs.292336	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210296_s_at	-0.423	8.183	-3.359	4.230e-03	0.117	-1.930	PXMP3	peroxisomal membrane protein 3, 35kDa	8	-78055048	BC005375	5828	8q21.1	Hs.437966 Hs.703022	19	neuron migration protein binding peroxisome peroxisomal membrane integral to peroxisomal membrane peroxisome organization nervous system development zinc ion binding membrane integral to membrane metal ion binding
226976_at	-0.425	7.837	-3.359	4.232e-03	0.117	-1.930	KPNA6	karyopherin alpha 6 (importin alpha 7)	1	32346230	D55880	23633	1p35.1-p34.3	Hs.470588 Hs.711019	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
203957_at	-0.487	6.571	-3.359	4.233e-03	0.117	-1.931	E2F6	E2F transcription factor 6	2	-11501951	NM_001952	1876	2p25.1	Hs.603093	24	regulation of transcription of G1/S-phase of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription corepressor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle
218185_s_at	-0.531	7.440	-3.359	4.237e-03	0.117	-1.932	ARMC1	armadillo repeat containing 1	8	-66677627	NM_018120	55156	8q13.1	Hs.269542	3	binding metal ion transport metal ion binding
226005_at	-0.850	8.974	-3.359	4.237e-03	0.117	-1.932	UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	17	-4119260	BG170762	7326	17p13.2 1q42	Hs.714345	12	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
207089_at	-1.436	6.766	-3.359	4.238e-03	0.117	-1.932	NRAP	nebulin-related anchoring protein	10	-115338572	AF005213	4892	10q24-q26	Hs.268788	14	actin binding actin binding protein binding fascia adherens muscle tendon junction biological_process zinc ion binding metal ion binding muscle alpha-actinin binding
201313_at	0.387	5.063	3.358	4.239e-03	0.117	-1.932	ENO2	enolase 2 (gamma, neuronal)	12	6893874	NM_001975	2026	12p13	Hs.511915	41	phosphopyruvate hydratase complex magnesium ion binding phosphopyruvate hydratase activity intracellular cytoplasm plasma membrane glycolysis lyase activity perikaryon	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways RNA degradation
226907_at	-1.019	7.905	-3.358	4.241e-03	0.117	-1.932	PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C	6	150505880	N32557	81706	6q24.3-q25.3	Hs.486798	10	protein serine/threonine phosphatase inhibitor activity protein binding cytoplasm membrane regulation of phosphorylation
223051_at	-0.332	9.444	-3.358	4.241e-03	0.117	-1.932	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	AF277178	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
226607_at	-0.832	8.310	-3.357	4.249e-03	0.117	-1.934	C20orf194	chromosome 20 open reading frame 194	20	-3177947	AI498144	25943	20p13	Hs.516853	7
211622_s_at	0.529	5.882	3.357	4.251e-03	0.117	-1.935	ARF3	ADP-ribosylation factor 3	12	-47616258	M33384	377	12q13	Hs.119177 Hs.715625	24	nucleotide binding GTPase activity GTP binding intracellular Golgi apparatus small GTPase mediated signal transduction protein transport vesicle-mediated transport
215921_at	-0.643	4.781	-3.357	4.252e-03	0.117	-1.935	NPIPL1	nuclear pore complex interacting protein-like 1	16		AC002544	440350	16p11.2		1	extracellular region
229027_at	-0.963	5.002	-3.357	4.253e-03	0.117	-1.935	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AI241945	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
236223_s_at	0.227	2.430	3.357	4.256e-03	0.117	-1.936	RIT1	Ras-like without CAAX 1	1	-154134224	AL037450	6016	1q22	Hs.491234	17	nucleotide binding calmodulin binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction small GTPase mediated signal transduction
208873_s_at	-0.446	9.513	-3.356	4.260e-03	0.117	-1.937	REEP5	receptor accessory protein 5	5	-112239979	BC000232	7905	5q22-q23	Hs.429608	11	molecular_function protein binding biological_process membrane integral to membrane
212381_at	-0.909	6.939	-3.355	4.270e-03	0.117	-1.939	USP24	ubiquitin specific peptidase 24	1	-55304619	BF444943	23358	1p32.3	Hs.477009	13	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
214196_s_at	-0.399	4.478	-3.354	4.274e-03	0.117	-1.940	TPP1	tripeptidyl peptidase I	11	-6590572	AA602532	1200	11p15	Hs.523454	51	serine-type endopeptidase activity protein binding soluble fraction mitochondrion lysosome lysosome proteolysis lipid metabolic process lysosome organization nervous system development peptidase activity tripeptidyl-peptidase activity tripeptidyl-peptidase activity peptide binding melanosome peptide catabolic process bone resorption neuromuscular process controlling balance	Lysosome
214787_at	-0.407	3.839	-3.354	4.277e-03	0.117	-1.940	DENND4A	DENN/MADD domain containing 4A	15	-63740012	BE268538	10260	15q22.31	Hs.654567	8	DNA binding protein binding nucleus regulation of transcription, DNA-dependent
203685_at	-0.747	7.488	-3.354	4.279e-03	0.117	-1.941	BCL2	B-cell CLL/lymphoma 2	18	-59136166, -58941558	NM_000633	596	18q21.3 18q21.33	Hs.150749	705	G1/S transition of mitotic cell cycle protein phosphatase type 2A complex cell morphogenesis response to acid ovarian follicle development ureteric bud development branching involved in ureteric bud morphogenesis behavioral fear response response to hypoxia B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development renal system process intracellular membrane fraction nucleus cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol calcineurin complex protein amino acid dephosphorylation melanin metabolic process oxygen and reactive oxygen species metabolic process regulation of nitrogen utilization anti-apoptosis humoral immune response response to oxidative stress actin filament organization female pregnancy cell aging response to nutrient transcription factor binding cell death positive regulation of cell proliferation male gonad development activation of pro-apoptotic gene products response to radiation response to heat response to external stimulus response to toxin post-embryonic development organ morphogenesis response to inorganic substance response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration membrane integral to membrane cell-cell adhesion transcription activator activity peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis hemopoiesis negative regulation of ossification negative regulation of cell growth negative regulation of cell migration response to caffeine hair follicle morphogenesis axon regeneration regulation of protein stability nuclear membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization negative regulation of myeloid cell apoptosis T cell differentiation in the thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine stimulus response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation response to drug response to hydrogen peroxide protein homodimerization activity T cell homeostasis positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment response to peptide hormone stimulus regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis ear development response to estrogen stimulus regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability protein heterodimerization activity focal adhesion formation positive regulation of pigmentation during development spleen development thymus development gut morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue response to glucocorticoid stimulus BH3 domain binding defense response to virus regulation of cell cycle response to protein stimulus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport apoptosis in response to endoplasmic reticulum stress	Apoptosis Focal adhesion Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Prostate cancer Small cell lung cancer
221959_at	-0.346	5.923	-3.353	4.284e-03	0.117	-1.942	FAM110B	family with sequence similarity 110, member B	8	59069666	BE672313	90362	8q12.1	Hs.154652	7	cytoplasm mitochondrion centrosome
218326_s_at	-0.722	6.152	-3.352	4.293e-03	0.117	-1.944	LGR4	leucine-rich repeat-containing G protein-coupled receptor 4	11	-27344083	NM_018490	55366	11p14-p13	Hs.502176	6	receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane protein-hormone receptor activity
241280_at	0.290	4.639	3.352	4.294e-03	0.117	-1.944	ALDOB	aldolase B, fructose-bisphosphate	9	-103222662	AV650426	229	9q21.3-q22.2	Hs.530274	40	fructose-bisphosphate aldolase activity microtubule organizing center glycolysis NADH oxidation cytoskeletal protein binding metabolic process lyase activity fructose 1,6-bisphosphate metabolic process positive regulation of ATPase activity centriolar satellite identical protein binding ATPase binding fructose binding vacuolar proton-transporting V-type ATPase complex assembly	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
222494_at	-0.296	9.126	-3.352	4.294e-03	0.117	-1.944	FOXN3	forkhead box N3	14	-88692268, -88692268	AW051527	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
216008_s_at	-0.358	7.424	-3.352	4.299e-03	0.117	-1.945	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	AV694434	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
225545_at	-0.973	9.032	-3.352	4.299e-03	0.117	-1.945	EEF2K	eukaryotic elongation factor-2 kinase	16	22125092	BF001312	29904	16p12.2	Hs.498892	22	nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP binding cytoplasm cytosol translational elongation protein amino acid phosphorylation translation factor activity, nucleic acid binding transferase activity
201928_at	0.266	6.967	3.351	4.302e-03	0.117	-1.946	PKP4	plakophilin 4	2	159021721	AA194254	8502	2q23-q31	Hs.407580	27	protein binding cell adhesion desmosome
203327_at	-0.440	8.398	-3.351	4.303e-03	0.117	-1.946	IDE	insulin-degrading enzyme	10	-94203579	N22903	3416	10q23-q25	Hs.500546	94	metalloendopeptidase activity signal transducer activity ATP binding extracellular space soluble fraction cytoplasm peroxisome proteolysis signal transduction sex differentiation peptidase activity zinc ion binding bradykinin catabolic process protein homodimerization activity metal ion binding beta-amyloid metabolic process	Alzheimer's disease
203896_s_at	0.563	5.565	3.351	4.305e-03	0.117	-1.946	PLCB4	phospholipase C, beta 4	20	9024931	NM_000933	5332	20p12	Hs.472101	17	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding intracellular signaling cascade lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
218773_s_at	0.293	10.273	3.350	4.311e-03	0.117	-1.948	MSRB2	methionine sulfoxide reductase B2	10	23424432	NM_012228	22921	10p12	Hs.461420	14	protein-methionine-R-oxide reductase activity transcription factor activity mitochondrion peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity protein repair metal ion binding oxidation reduction
207507_s_at	0.430	12.269	3.350	4.314e-03	0.117	-1.948	ATP5G3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	2	-175749231, -175749231	NM_001689	518	2q31.1	Hs.429	10	transporter activity protein binding mitochondrion mitochondrial proton-transporting ATP synthase complex ion transport lipid binding hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting ATP synthase complex, coupling factor F(o)	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
236094_at	0.318	4.851	3.349	4.319e-03	0.117	-1.949	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10	114699998	BF696202	6934	10q25.3	Hs.593995	246	blood vessel development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter anti-apoptosis cell cycle arrest beta-catenin binding transcription factor binding cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process specific transcriptional repressor activity protein kinase binding pancreas development positive regulation of insulin secretion regulation of hormone metabolic process glucose homeostasis fat cell differentiation regulation of transcription myoblast cell fate commitment Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
203935_at	-0.593	7.479	-3.348	4.328e-03	0.117	-1.951	ACVR1	activin A receptor, type I	2	-158301204, -158301204	NM_001105	90	2q23-q24	Hs.470316	53	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding patterning of blood vessels urogenital system development in utero embryonic development gastrulation with mouth forming second mesoderm formation neural crest cell migration acute inflammatory response receptor activity ATP binding protein amino acid phosphorylation transforming growth factor beta receptor signaling pathway germ cell development determination of left/right symmetry mesoderm development heart development embryonic development membrane activin receptor activity, type I transferase activity manganese ion binding regulation of ossification positive regulation of bone mineralization BMP signaling pathway negative regulation of activin receptor signaling pathway protein homodimerization activity negative regulation of apoptosis apical part of cell positive regulation of osteoblast differentiation positive regulation of transcription SMAD binding activin receptor complex follistatin binding activin binding regulation of skeletal muscle tissue development transforming growth factor beta binding smooth muscle cell differentiation pharyngeal system development	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
227094_at	0.501	7.684	3.348	4.329e-03	0.117	-1.951	DHTKD1	dehydrogenase E1 and transketolase domain containing 1	10	12150939	AI934407	55526	10p14	Hs.104980 Hs.711138	3	oxoglutarate dehydrogenase (succinyl-transferring) activity mitochondrion glycolysis oxidoreductase activity thiamin pyrophosphate binding oxidation reduction
229272_at	-0.947	5.271	-3.348	4.329e-03	0.117	-1.951	FNBP4	formin binding protein 4	11	-47694644	AI083506	23360	11p11.2	Hs.6834	11	protein binding
219737_s_at	-0.823	5.413	-3.348	4.332e-03	0.117	-1.952	PCDH9	protocadherin 9	13	-65774967	AI524125	5101	13q14.3-q21.1	Hs.654709 Hs.719302	8	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
201858_s_at	0.500	7.654	3.348	4.335e-03	0.117	-1.953	SRGN	serglycin	10	70517833	J03223	5552	10q22.1	Hs.1908	30	protein binding protein binding extracellular region extracellular space Golgi apparatus apoptosis negative regulation of bone mineralization biomineral formation mast cell secretory granule organization T cell secretory granule organization maintenance of protease location in mast cell secretory granule maintenance of granzyme B location in T cell secretory granule mast cell granule negative regulation of cytokine secretion protein maturation by peptide bond cleavage
203373_at	0.678	4.920	3.346	4.345e-03	0.117	-1.955	SOCS2	suppressor of cytokine signaling 2	12	92487728	NM_003877	8835	12q	Hs.485572	40	regulation of cell growth SH3/SH2 adaptor activity growth hormone receptor binding prolactin receptor binding insulin-like growth factor receptor binding protein binding cytoplasm anti-apoptosis intracellular signaling cascade JAK-STAT cascade JAK pathway signal transduction adaptor activity negative regulation of signal transduction modification-dependent protein catabolic process response to estradiol stimulus growth hormone receptor signaling pathway	Jak-STAT signaling pathway Insulin signaling pathway Type II diabetes mellitus
220478_at	0.284	5.601	3.346	4.348e-03	0.117	-1.956	APOL5	apolipoprotein L, 5	22	34443864	NM_030642	80831	22q12.3	Hs.326561	3	protein binding extracellular region cytoplasm lipid metabolic process lipid transport high-density lipoprotein binding lipid binding lipoprotein metabolic process
204114_at	0.502	5.841	3.346	4.354e-03	0.117	-1.957	NID2	nidogen 2 (osteonidogen)	14	-51541269	NM_007361	22795	14q21-q22	Hs.369840	15	calcium ion binding collagen binding extracellular region basement membrane cell adhesion cell-matrix adhesion bioluminescence membrane protein-chromophore linkage
235344_at	-0.652	6.993	-3.345	4.356e-03	0.117	-1.957	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	BG288054	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
227064_at	-0.457	9.157	-3.345	4.357e-03	0.117	-1.958	ANKRD40	ankyrin repeat domain 40	17	-46125550	AV712687	91369	17q21.33	Hs.463426	2
219461_at	0.307	4.916	3.345	4.362e-03	0.117	-1.959	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	15	38296920, 38319326	AJ236915	56924	15q14	Hs.513645	13	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
243814_at	0.294	4.688	3.344	4.363e-03	0.117	-1.959	ZMYND8	zinc finger, MYND-type containing 8	20	-45271787	AW135141	23613	20q13.12	Hs.446240 Hs.658553 Hs.668465	17	protein binding zinc ion binding metal ion binding
202734_at	-0.436	7.090	-3.344	4.365e-03	0.117	-1.959	TRIP10	thyroid hormone receptor interactor 10	19	6690706	NM_004240	9322	19p13.3	Hs.515094	28	cytoplasm lysosome Golgi apparatus cytoskeleton plasma membrane cell cortex endocytosis signal transduction lipid binding actin cytoskeleton organization identical protein binding perinuclear region of cytoplasm	Insulin signaling pathway
226161_at	-0.391	6.323	-3.344	4.369e-03	0.117	-1.960	SLC30A6	solute carrier family 30 (zinc transporter), member 6	2	32244436	BF793552	55676	2p22.3	Hs.23248	7	Golgi apparatus cation transport zinc ion transport zinc ion binding cation transmembrane transporter activity membrane integral to membrane
206867_at	0.292	5.045	3.344	4.370e-03	0.117	-1.960	GCKR	glucokinase (hexokinase 4) regulator	2	27573209	NM_001486	2646	2p23	Hs.89771	41	protein import into nucleus, translocation cellular glucose homeostasis enzyme inhibitor activity protein binding nucleus nucleoplasm cytosol
229116_at	-1.235	6.480	-3.344	4.370e-03	0.117	-1.960	CNKSR2	connector enhancer of kinase suppressor of Ras 2	X	21302900	AI670947	22866	Xp22.12	Hs.555917	10	protein binding cytoplasm centrosome plasma membrane regulation of signal transduction
1558315_s_at	-0.447	3.268	-3.343	4.372e-03	0.117	-1.961	HOOK3	hook homolog 3 (Drosophila)	8	42871189	AV710762	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
236866_at	0.361	4.787	3.343	4.375e-03	0.117	-1.961	GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase	16	-87407642	AA884446	2588	16q24.3	Hs.271383	39	N-acetylgalactosamine-4-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process N-acetylgalactosamine-6-sulfatase activity	Glycosaminoglycan degradation Metabolic pathways Lysosome
212309_at	-0.501	8.706	-3.343	4.377e-03	0.117	-1.962	CLASP2	cytoplasmic linker associated protein 2	3	-33512741	AV725315	23122	3p22.3	Hs.108614	17	condensed chromosome kinetochore protein binding cytoplasm Golgi apparatus centrosome spindle kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity galactoside 2-alpha-L-fucosyltransferase activity regulation of microtubule polymerization or depolymerization microtubule plus-end binding cell division
1560116_a_at	-0.873	8.323	-3.343	4.379e-03	0.117	-1.962	NEDD1	neural precursor cell expressed, developmentally down-regulated 1	12	95825131, 95825374	AL832468	121441	12q23.1	Hs.270084	10	pericentriolar material spindle pole cytoplasm centriole microtubule basal body cell cycle mitosis apical part of cell cell division
1565269_s_at	-0.669	5.359	-3.343	4.379e-03	0.117	-1.962	ATF1	activating transcription factor 1	12	49444085	AF047022	466	12q13	Hs.648565	45	transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
217757_at	0.505	9.397	3.342	4.384e-03	0.117	-1.963	A2M	alpha-2-macroglobulin	12	-9111570	NM_000014	2	12p13.3-p12.3	Hs.212838	131	negative regulation of complement activation, lectin pathway serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space enzyme binding interleukin-8 binding interleukin-1 binding platelet alpha granule lumen tumor necrosis factor binding	Complement and coagulation cascades
203463_s_at	-0.413	6.266	-3.342	4.386e-03	0.117	-1.964	EPN2	epsin 2	17	19081282	H05668	22905	17p11.2	Hs.715517	13	cytoplasm endocytosis lipid binding clathrin-coated vesicle cytoplasmic vesicle	Endocytosis
204847_at	-0.604	6.957	-3.341	4.390e-03	0.117	-1.964	ZBTB11	zinc finger and BTB domain containing 11	3	-102850972	NM_014415	27107	3q12.3	Hs.655286 Hs.715553 Hs.715814	5	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
1555844_s_at	-0.449	8.515	-3.341	4.396e-03	0.118	-1.966	HNRNPM	heterogeneous nuclear ribonucleoprotein M	19	8415802	AL713781	4670	19p13.3-p13.2	Hs.465808 Hs.666214	28	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding nucleus spliceosomal complex nucleolus integral to plasma membrane RNA splicing protein domain specific binding
234947_s_at	-0.484	7.166	-3.340	4.402e-03	0.118	-1.967	C10orf84	chromosome 10 open reading frame 84	10	-120058561	AK026630	63877	10q26.11	Hs.372309	5
226626_at	-0.500	7.137	-3.339	4.413e-03	0.118	-1.969	THOC2	THO complex 2	X	-122562092	AL133117	57187	Xq25-q26.3	Hs.592243	10	RNA binding protein binding nucleus mRNA processing transport RNA splicing mRNA transport
220234_at	0.426	4.739	3.337	4.427e-03	0.118	-1.972	CA8	carbonic anhydrase VIII	8	-61263976	NM_004056	767	8q11-q12	Hs.654388	14	carbonate dehydratase activity protein binding cytoplasm one-carbon metabolic process zinc ion binding metal ion binding phosphoinositide-mediated signaling	Nitrogen metabolism
212387_at	0.450	7.692	3.337	4.432e-03	0.118	-1.973	TCF4	transcription factor 4	18	-51040559	BG495771	6925	18q21.1	Hs.605153	55	transcription factor activity protein binding nucleus regulation of transcription positive regulation of transcription, DNA-dependent protein heterodimerization activity
228494_at	-0.627	6.754	-3.335	4.452e-03	0.118	-1.977	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A	7	94374884	AI888150	55607	7q21.3	Hs.21816	12	actin binding protein binding cytoplasm cytoskeleton actin filament organization multicellular organismal development nervous system development synaptosome cell junction cell differentiation filopodium cortical actin cytoskeleton dendritic spine synapse
212245_at	-0.392	8.243	-3.335	4.453e-03	0.118	-1.978	MCFD2	multiple coagulation factor deficiency 2	2	-46982518	AL567779	90411	2p21	Hs.293689	19	calcium ion binding extracellular region endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus protein transport vesicle-mediated transport carboxylic acid metabolic process
221620_s_at	0.525	9.078	3.334	4.454e-03	0.118	-1.978	APOO	apolipoprotein O	X	-23761397	AF061264	79135	Xp22.11	Hs.495851	6	extracellular region lipid transport membrane integral to membrane very-low-density lipoprotein particle low-density lipoprotein particle high-density lipoprotein particle
213463_s_at	-0.368	6.371	-3.334	4.455e-03	0.118	-1.978	FAM149B1	family with sequence similarity 149, member B1	10	74597882	AW300504	317662	10q22.2	Hs.408577	4
208935_s_at	0.337	3.839	3.334	4.457e-03	0.118	-1.979	LGALS8	lectin, galactoside-binding, soluble, 8	1	234748187, 234753361, 234753699	L78132	3964	1q42-q43	Hs.4082 Hs.708114	29	sugar binding extracellular space cytoplasm
217216_x_at	-0.399	5.247	-3.334	4.461e-03	0.118	-1.979	MLH3	mutL homolog 3 (E. coli)	14	-74550219	AC006530	27030	14q24.3	Hs.436650	28	satellite DNA binding protein binding ATP binding nucleus mismatch repair response to DNA damage stimulus reciprocal meiotic recombination mismatched DNA binding	Mismatch repair
224973_at	-0.356	3.044	-3.333	4.466e-03	0.118	-1.980	FAM46A	family with sequence similarity 46, member A	6	-82512165	AL078599	55603	6q14	Hs.10784	11
226037_s_at	-0.468	6.758	-3.333	4.467e-03	0.118	-1.980	TAF9B	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa	X	-77271900, 1383006	AL049589	51616	Xq13.1-q21.1	Hs.592248 Hs.643614 Hs.714006	8	DNA binding transcription corepressor activity protein binding nucleus transcription factor TFIID complex transcription initiation negative regulation of specific transcription from RNA polymerase II promoter positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptosis regulation of transcription	Basal transcription factors
208752_x_at	-0.465	9.727	-3.333	4.467e-03	0.118	-1.981	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AI888672	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
227693_at	-0.515	6.115	-3.333	4.467e-03	0.118	-1.981	WDR20	WD repeat domain 20	14	101675964, 101675964, 101675964	AI092930	91833	14q32.31	Hs.36859	7
211212_s_at	-0.583	4.231	-3.333	4.469e-03	0.118	-1.981	ORC5L	origin recognition complex, subunit 5-like (yeast)	7	-103595859, -103554023	AF081459	5001	7q22.1	Hs.432948	28	nucleotide binding DNA replication origin binding ATP binding nucleus nucleoplasm DNA replication DNA replication DNA replication initiation identical protein binding	Cell cycle
201785_at	0.648	8.767	3.333	4.469e-03	0.118	-1.981	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)	14	-20339354, -20339354	NM_002933	6035	14q11.2	Hs.78224	42	nucleic acid binding endonuclease activity pancreatic ribonuclease activity extracellular region hydrolase activity
1562403_a_at	-0.507	7.147	-3.332	4.472e-03	0.118	-1.982	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3	14	-69580686, -69580686, -69580686	AK096553	6547	14q24.1	Hs.337696	16	calcium:sodium antiporter activity calcium ion binding calmodulin binding ion transport sodium ion transport calcium ion transport cell communication antiporter activity membrane integral to membrane sodium ion binding	Calcium signaling pathway
212460_at	-0.456	6.872	-3.332	4.477e-03	0.118	-1.982	C14orf147	chromosome 14 open reading frame 147	14	-33971894	BE738425	171546	14q13.1	Hs.269909	5	serine C-palmitoyltransferase activity protein binding endoplasmic reticulum membrane integral to membrane serine C-palmitoyltransferase complex sphingolipid biosynthetic process
203339_at	-0.627	8.822	-3.332	4.481e-03	0.118	-1.983	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	2	-172348160	AI887457	8604	2q24	Hs.470608	27	transporter activity L-glutamate transmembrane transporter activity calcium ion binding protein binding mitochondrion mitochondrial inner membrane transport L-aspartate transmembrane transporter activity aspartate transport L-glutamate transport membrane integral to membrane malate-aspartate shuttle response to calcium ion
227678_at	-1.142	6.963	-3.331	4.484e-03	0.118	-1.984	XRCC6BP1	XRCC6 binding protein 1	12	56621711	AI628122	91419	12q14.1	Hs.61188	3	DNA-dependent protein kinase activity DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
210836_x_at	-0.443	3.184	-3.331	4.485e-03	0.118	-1.984	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	AF012073	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
228652_at	0.469	7.520	3.330	4.493e-03	0.118	-1.986	ZNF776	zinc finger protein 776	19	62949975	AI279532	284309	19q13.43	Hs.109540	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
205826_at	-0.943	9.988	-3.330	4.495e-03	0.118	-1.986	MYOM2	myomesin (M-protein) 2, 165kDa	8	1980564	NM_003970	9172	8p23.3	Hs.443683	9	striated muscle thick filament striated muscle contraction structural constituent of muscle
221763_at	-0.565	7.283	-3.330	4.497e-03	0.118	-1.987	JMJD1C	jumonji domain containing 1C	10	-64596993, -64596993	AI694023	221037	10q21.3	Hs.413416	10	iron ion binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding thyroid hormone receptor binding oxidation reduction
213508_at	-0.526	7.095	-3.329	4.502e-03	0.119	-1.988	C14orf147	chromosome 14 open reading frame 147	14	-33971894	AA142942	171546	14q13.1	Hs.269909	5	serine C-palmitoyltransferase activity protein binding endoplasmic reticulum membrane integral to membrane serine C-palmitoyltransferase complex sphingolipid biosynthetic process
221883_at	-0.457	6.012	-3.328	4.517e-03	0.119	-1.991	PKNOX1	PBX/knotted 1 homeobox 1	21	43267711	AA133342	5316	21q22.3	Hs.431043	25	angiogenesis specific RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex cytoplasm hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity
227250_at	-0.780	6.666	-3.327	4.520e-03	0.119	-1.991	KREMEN1	kringle containing transmembrane protein 1	22	27799065, 27799105	BF221745	83999	22q12.1	Hs.229335	11	molecular_function membrane fraction cell communication membrane integral to membrane Wnt receptor signaling pathway
241533_at	0.280	5.388	3.327	4.522e-03	0.119	-1.992	LOC731656	hypothetical LOC731656	1		AV652367	731656		Hs.702477	1
1555057_at	-0.308	4.205	-3.326	4.528e-03	0.119	-1.993	NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	5	52892221	AB062482	4724	5q11.1	Hs.528222	28	regulation of protein amino acid phosphorylation mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport brain development NADH dehydrogenase (ubiquinone) activity membrane oxidoreductase activity, acting on NADH or NADPH cAMP-mediated signaling electron transport chain mitochondrial respiratory chain complex I assembly cellular respiration positive regulation of fibroblast proliferation response to cAMP respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
225427_s_at	0.398	8.569	3.326	4.536e-03	0.119	-1.995	APOA1BP	apolipoprotein A-I binding protein	1	154828181	BE871169	128240	1q22-q21.2	Hs.528320	4	protein binding extracellular region biological_process
235779_at	0.279	3.073	3.325	4.539e-03	0.119	-1.995	LOC284408	hypothetical protein LOC284408	19		AW467077	284408	19q13.13	Hs.570010	1
226298_at	-0.624	6.103	-3.325	4.542e-03	0.119	-1.996	RUNDC1	RUN domain containing 1	17	38386107	BE394201	146923	17q21.31	Hs.632255	2
206567_s_at	-0.521	7.452	-3.324	4.555e-03	0.119	-1.999	PHF20	PHD finger protein 20	20	33823336	NM_016436	51230	20q11.22-q11.23	Hs.517044	11	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
230292_at	0.500	6.050	3.321	4.577e-03	0.120	-2.003	LOC100131993	similar to hCG2020760	13		AA868809	100131993	13q14.2	Hs.709358
212485_at	-0.562	7.334	-3.321	4.581e-03	0.120	-2.004	GPATCH8	G patch domain containing 8	17	-39828175	AU146596	23131	17q21.31	Hs.463129	8	molecular_function cellular_component biological_process
224370_s_at	-0.650	4.744	-3.317	4.613e-03	0.121	-2.010	CAPS2	calcyphosine 2	12	-73956025	AF251056	84698	12q21.1-q21.2	Hs.407154	6	calcium ion binding
202739_s_at	-0.767	8.161	-3.316	4.624e-03	0.121	-2.012	PHKB	phosphorylase kinase, beta	16	46052710	NM_000293	5257	16q12-q13	Hs.78060	13	catalytic activity calmodulin binding plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy	Calcium signaling pathway Insulin signaling pathway
205495_s_at	0.521	4.997	3.316	4.625e-03	0.121	-2.013	GNLY	granulysin	2	85774924	NM_006433	10578	2p11.2	Hs.105806	36	extracellular region extracellular space xenobiotic metabolic process cellular defense response defense response to bacterium defense response to fungus
205348_s_at	0.566	5.722	3.316	4.631e-03	0.121	-2.014	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	7	95239753	NM_004411	1780	7q21.3-q22.1	Hs.440364	17	microtubule motor activity protein binding cytoplasmic dynein complex microtubule microtubule binding vesicle transport along microtubule perinuclear region of cytoplasm
215365_at	0.301	4.533	3.315	4.637e-03	0.121	-2.015	CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10	18469611, 18469815, 18589589, 18669619, 18729518	AK022426	783	10p12	Hs.709353	30	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane integral to plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport neuromuscular junction development	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
208840_s_at	-0.716	6.285	-3.313	4.655e-03	0.121	-2.019	G3BP2	GTPase activating protein (SH3 domain) binding protein 2	4	-76786976, -76786976	AU149503	9908	4q21.1	Hs.303676	15	nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport
214065_s_at	0.302	4.956	3.313	4.660e-03	0.121	-2.020	CIB2	calcium and integrin binding family member 2	15	-76184045	BG251252	10518	15q24	Hs.129867	6	calcium ion binding protein binding
217183_at	0.243	5.383	3.312	4.666e-03	0.121	-2.021	LDLR	low density lipoprotein receptor	19	11061056	S70123	3949	19p13.3	Hs.213289 Hs.713967	374	transmembrane receptor activity low-density lipoprotein receptor activity calcium ion binding endosome plasma membrane plasma membrane integral to plasma membrane coated pit protein amino acid O-linked glycosylation lipid metabolic process lipid transport endocytosis steroid metabolic process cholesterol metabolic process endosome membrane very-low-density lipoprotein receptor activity intestinal cholesterol absorption clathrin-coated endocytic vesicle membrane low-density lipoprotein particle low-density lipoprotein particle clearance lipoprotein catabolic process cholesterol homeostasis interspecies interaction between organisms	Endocytosis
213684_s_at	-0.598	12.122	-3.312	4.667e-03	0.121	-2.021	PDLIM5	PDZ and LIM domain 5	4	95592060, 95592060	BF671400	10611	4q22	Hs.480311	34	actin binding protein kinase C binding protein binding membrane fraction cytosol zinc ion binding actin cytoskeleton Z disc actinin binding metal ion binding
1556988_s_at	-0.330	6.916	-3.311	4.672e-03	0.121	-2.022	CHD1L	chromodomain helicase DNA binding protein 1-like	1	145180914	BE220618	9557	1q12	Hs.191164	12	nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity
229700_at	0.695	5.373	3.311	4.680e-03	0.122	-2.023	ZNF738	zinc finger protein 738	19	21333574	BE966267	148203	19p12	Hs.124384 Hs.359535	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent
200627_at	-0.563	10.402	-3.310	4.681e-03	0.122	-2.024	PTGES3	prostaglandin E synthase 3 (cytosolic)	12	-55343391	BC003005	10728	12 12q13.3	Hs.50425	36	telomere maintenance chromosome, telomeric region prostaglandin biosynthetic process telomerase activity telomerase holoenzyme complex cytoplasm fatty acid biosynthetic process signal transduction isomerase activity prostaglandin-E synthase activity unfolded protein binding
225024_at	-0.352	6.693	-3.309	4.692e-03	0.122	-2.026	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B	20	36095361	AL117521	58490	20q11.21-q12	Hs.278839	7
235863_at	-0.395	6.936	-3.309	4.694e-03	0.122	-2.026	JSRP1	junctional sarcoplasmic reticulum protein 1	19	-2203251	AI805145	126306	19p13.3	Hs.712901	4	membrane sarcoplasmic reticulum membrane
1558700_s_at	0.634	4.153	3.309	4.696e-03	0.122	-2.027	ZNF260	zinc finger protein 260	19	-41693433	BC042676	339324	19q13.12	Hs.18103	5	DNA binding intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
223191_at	-0.359	10.153	-3.309	4.697e-03	0.122	-2.027	COX16	COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)	14	-69861551	AF151037	51241	14q24.2	Hs.709581	5	mitochondrion membrane integral to membrane mitochondrial membrane
205168_at	0.288	4.954	3.309	4.698e-03	0.122	-2.027	DDR2	discoidin domain receptor tyrosine kinase 2	1	160868851	NM_006182	4921	1q23.3	Hs.275757 Hs.593833	26	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation cell adhesion signal transduction transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell proliferation membrane transferase activity
223503_at	0.391	3.412	3.308	4.700e-03	0.122	-2.028	TMEM163	transmembrane protein 163	2	-134929800	AF255647	81615	2q21.3	Hs.369471 Hs.595089	5	membrane integral to membrane
204160_s_at	-0.624	7.255	-3.308	4.701e-03	0.122	-2.028	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)	6	46205659	AW194947	22875	6p21.1	Hs.643497	4	metabolic process membrane integral to membrane hydrolase activity
218537_at	-0.978	8.793	-3.308	4.702e-03	0.122	-2.028	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)	16	-3012626	NM_017885	54985	16p13.3	Hs.719259	2	nucleus cytoplasm
203390_s_at	0.416	4.767	3.308	4.706e-03	0.122	-2.029	KIF3C	kinesin family member 3C	2	-26002958	NM_002254	3797	2p23	Hs.21611	9	nucleotide binding microtubule motor activity ATP binding kinesin complex microtubule microtubule-based movement
214550_s_at	-0.443	6.476	-3.307	4.713e-03	0.122	-2.030	TNPO3	transportin 3	7	-128382183	AF145029	23534	7q32.1	Hs.193613	16	receptor activity protein binding nucleus cytoplasm protein transport
203266_s_at	-0.404	6.793	-3.306	4.720e-03	0.122	-2.031	MAP2K4	mitogen-activated protein kinase kinase 4	17	11864859	NM_003010	6416	17p11.2	Hs.514681	92	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding protein amino acid phosphorylation signal transduction JNK cascade transferase activity	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection
238841_at	0.363	5.301	3.306	4.723e-03	0.122	-2.032	PTPDC1	protein tyrosine phosphatase domain containing 1	9	95832896, 95886566	AA651920	138639	9q22.32	Hs.437943	2	protein tyrosine phosphatase activity protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
32128_at	0.370	3.617	3.305	4.730e-03	0.122	-2.033	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	17	31415755	Y13710	6362	17q11.2	Hs.143961	35	extracellular region extracellular space chemotaxis inflammatory response immune response signal transduction cell-cell signaling chemokine activity response to biotic stimulus	Cytokine-cytokine receptor interaction Chemokine signaling pathway
225853_at	-0.522	7.011	-3.304	4.740e-03	0.122	-2.035	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1	14	-52311660	BE789346	64841	14q22.1	Hs.702056	5	glucosamine 6-phosphate N-acetyltransferase activity late endosome ER-Golgi intermediate compartment Golgi apparatus metabolic process acyltransferase activity membrane transferase activity	Amino sugar and nucleotide sugar metabolism
206453_s_at	-0.532	11.058	-3.304	4.741e-03	0.122	-2.035	NDRG2	NDRG family member 2	14	-20554761, -20554761	NM_016250	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
215034_s_at	0.414	6.910	3.304	4.741e-03	0.122	-2.035	TM4SF1	transmembrane 4 L six family member 1	3	-150569494	AI189753	4071	3q21-q25	Hs.715499	16	molecular_function integral to plasma membrane biological_process membrane
231867_at	1.451	3.793	3.304	4.743e-03	0.122	-2.036	ODZ2	odz, odd Oz/ten-m homolog 2 (Drosophila)	5	166644420	AB032953	57451	5q34	Hs.654631 Hs.715483	9	signal transduction membrane integral to membrane
202717_s_at	-0.623	6.828	-3.304	4.746e-03	0.122	-2.036	CDC16	cell division cycle 16 homolog (S. cerevisiae)	13	114018463	NM_003903	8881	13q34	Hs.374127	32	binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
200882_s_at	-0.360	9.443	-3.303	4.755e-03	0.122	-2.038	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	NM_002810	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
207508_at	0.416	11.906	3.303	4.757e-03	0.122	-2.039	ATP5G3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	2	-175749231, -175749231	NM_001689	518	2q31.1	Hs.429	10	transporter activity protein binding mitochondrion mitochondrial proton-transporting ATP synthase complex ion transport lipid binding hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting ATP synthase complex, coupling factor F(o)	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
204772_s_at	-0.490	5.919	-3.302	4.759e-03	0.122	-2.039	TTF1	transcription termination factor, RNA polymerase I	9	-134240757	NM_007344	7270	9q34.13	Hs.54780	18	DNA binding transcription termination factor activity nucleus nucleoplasm nucleolus transcription termination negative regulation of DNA replication regulation of transcription
205560_at	0.296	4.343	3.302	4.761e-03	0.122	-2.039	PCSK5	proprotein convertase subtilisin/kexin type 5	9	77695379	NM_006200	5125	9q21.3	Hs.368542	40	kidney development kidney development renin secretion into blood stream serine-type endopeptidase activity extracellular region extracellular space Golgi apparatus Golgi lumen signal peptide processing proteolysis cell-cell signaling heart development embryo implantation peptidase activity anterior/posterior pattern formation viral assembly, maturation, egress, and release secretory granule respiratory tube development nerve growth factor processing limb morphogenesis cytokine biosynthetic process peptide binding peptide biosynthetic process embryonic gut development embryonic skeletal system development
206117_at	-0.589	13.220	-3.302	4.764e-03	0.122	-2.040	TPM1	tropomyosin 1 (alpha)	15	61121890, 61121890, 61127688	NM_000366	7168	15q22.1	Hs.133892	76	stress fiber positive regulation of heart rate by epinephrine actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction cytoskeleton organization regulation of heart contraction structural constituent of muscle sarcomere muscle filament sliding negative regulation of cell migration ruffle organization bleb ruffle membrane positive regulation of ATPase activity cellular response to reactive oxygen species wound healing sarcomere organization positive regulation of cell adhesion positive regulation of stress fiber formation ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
224961_at	-0.340	6.565	-3.302	4.766e-03	0.122	-2.040	SCYL2	SCY1-like 2 (S. cerevisiae)	12	99185679	AB037781	55681	12q23.1	Hs.506481	8	protein kinase activity binding ATP binding cytoplasm endosome Golgi apparatus protein amino acid phosphorylation endosome membrane membrane clathrin-coated vesicle cytoplasmic vesicle perinuclear region of cytoplasm
210886_x_at	0.398	6.997	3.301	4.768e-03	0.122	-2.041	TP53TG1	TP53 target 1 (non-protein coding)	7	-86792599	AB007457	11257	7q21.1	Hs.274329	3	signal transducer activity response to stress
202230_s_at	-0.465	8.096	-3.301	4.776e-03	0.122	-2.042	CHERP	calcium homeostasis endoplasmic reticulum protein	19	-16489699	NM_006387	10523	19p13.1	Hs.631627	5	molecular_function RNA binding cellular_component intracellular cytoplasm endoplasmic reticulum RNA processing nervous system development biological_process perinuclear region of cytoplasm
211105_s_at	-0.885	7.707	-3.300	4.786e-03	0.123	-2.044	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	18	75256759, 75256759, 75261313	U80918	4772	18q23	Hs.534074 Hs.701518	83	transcription factor activity FK506 binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter intracellular signaling cascade transcription activator activity	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
222237_s_at	0.535	5.013	3.298	4.804e-03	0.123	-2.048	ZFP112	zinc finger protein 112 homolog (mouse)	19	-49522545	AC084239	7771	19q13.2	Hs.48589	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552470_a_at	0.452	5.231	3.297	4.808e-03	0.123	-2.049	ABHD11	abhydrolase domain containing 11	7	-72789980, -72789935, -72788362, -72788362	NM_148914	83451	7q11.23	Hs.647045	9	molecular_function cellular_component biological_process hydrolase activity
223244_s_at	0.300	11.718	3.297	4.810e-03	0.123	-2.049	NDUFA12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	12	-93889240	AF217092	55967	12q22	Hs.506374	9	NADH dehydrogenase activity mitochondrion mitochondrial inner membrane transport response to oxidative stress respiratory gaseous exchange NADH dehydrogenase (ubiquinone) activity electron carrier activity membrane electron transport chain respiratory chain
229656_s_at	0.778	4.706	3.296	4.820e-03	0.123	-2.051	EML6	echinoderm microtubule associated protein like 6	2	54805652	AA236463	400954	2p16.2-p16.1	Hs.656692		cytoplasm microtubule
234071_at	-0.381	3.755	-3.295	4.835e-03	0.123	-2.054	DEPDC6	DEP domain containing 6	8	120955080	AU147969	64798	8q24.12	Hs.112981	11	protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size
213083_at	0.306	5.142	3.294	4.838e-03	0.123	-2.054	SLC35D2	solute carrier family 35, member D2	9	-98122809	AJ005866	11046	9q22.32	Hs.494556	6	nucleotide-sugar transmembrane transporter activity cellular_component Golgi apparatus biological_process carbohydrate transport membrane integral to membrane
1555725_a_at	0.582	9.523	3.294	4.840e-03	0.123	-2.055	RGS5	regulator of G-protein signaling 5	1	-161378720	AF493929	8490	1q23.1	Hs.24950	26	signal transducer activity GTPase activator activity regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction
214525_x_at	-0.357	6.037	-3.294	4.844e-03	0.123	-2.055	MLH3	mutL homolog 3 (E. coli)	14	-74550219	AB039667	27030	14q24.3	Hs.436650	28	satellite DNA binding protein binding ATP binding nucleus mismatch repair response to DNA damage stimulus reciprocal meiotic recombination mismatched DNA binding	Mismatch repair
222907_x_at	-0.792	5.851	-3.294	4.845e-03	0.123	-2.056	TMEM50B	transmembrane protein 50B	21	-33743317	BC000569	757	21q22.11	Hs.433668	8	molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane
209448_at	-0.558	6.969	-3.294	4.845e-03	0.123	-2.056	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	BC002439	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
206576_s_at	0.334	6.075	3.293	4.847e-03	0.123	-2.056	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	NM_001712	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
91684_g_at	0.401	6.190	3.293	4.850e-03	0.123	-2.057	EXOSC4	exosome component 4	8	145205509	AI571298	54512	8q24.3	Hs.632041	16	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
201078_at	-0.528	7.859	-3.293	4.850e-03	0.123	-2.057	TM9SF2	transmembrane 9 superfamily member 2	13	98951728	NM_004800	9375	13q32.3	Hs.654824	9	endosome integral to plasma membrane transport membrane
208941_s_at	0.305	6.086	3.293	4.853e-03	0.123	-2.057	SEPHS1	selenophosphate synthetase 1	10	-13400086	BC000941	22929	10p14	Hs.124027	8	nucleotide binding selenide, water dikinase activity ATP binding GTP binding protein modification process selenium binding transferase activity	Selenoamino acid metabolism Metabolic pathways
204482_at	0.525	7.508	3.293	4.855e-03	0.123	-2.057	CLDN5	claudin 5	22	-17890546	NM_003277	7122	22q11.21	Hs.505337	45	structural molecule activity plasma membrane tight junction integral to membrane calcium-independent cell-cell adhesion cell junction identical protein binding	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration
213717_at	-0.372	10.540	-3.293	4.855e-03	0.123	-2.058	LDB3	LIM domain binding 3	10	88418300, 88418405, 88418405	AA211481	11155	10q22.3-q23.2	Hs.657271	15	protein binding cytoplasm cytoskeleton zinc ion binding Z disc pseudopodium metal ion binding perinuclear region of cytoplasm
201780_s_at	-0.514	8.058	-3.293	4.856e-03	0.123	-2.058	RNF13	ring finger protein 13	3	151013164	NM_007282	11342	3q25.1	Hs.12333 Hs.712766	10	protein binding nucleus cytoplasm zinc ion binding metal ion binding
203460_s_at	-0.415	5.881	-3.292	4.864e-03	0.123	-2.059	PSEN1	presenilin 1	14	72672895	NM_007318	5663	14q24.3	Hs.3260	386	kinetochore endopeptidase activity membrane fraction integral to nuclear inner membrane nuclear outer membrane mitochondrion endoplasmic reticulum Golgi apparatus integral to plasma membrane membrane protein ectodomain proteolysis apoptosis anti-apoptosis chromosome segregation Notch receptor processing intracellular signaling cascade beta-catenin binding cell death peptidase activity cell surface membrane cell-cell adhesion protein processing PDZ domain binding endoplasmic reticulum calcium ion homeostasis regulation of phosphorylation amyloid precursor protein catabolic process positive regulation of catalytic activity	Wnt signaling pathway Notch signaling pathway Neurotrophin signaling pathway Alzheimer's disease
207335_x_at	0.377	10.749	3.291	4.868e-03	0.123	-2.060	ATP5I	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	4	-656224	NM_007100	521	4p16.3	Hs.85539	14	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
228328_at	-0.513	7.887	-3.291	4.871e-03	0.123	-2.061	KLHL28	kelch-like 28 (Drosophila)	14	-44463276	AI982758	54813	14q21.2	Hs.653206	5	protein binding
204223_at	0.509	5.014	3.291	4.872e-03	0.123	-2.061	PRELP	proline/arginine-rich end leucine-rich repeat protein	1	201711505	NM_002725	5549	1q32	Hs.632481	13	skeletal system development extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix cell aging
226368_at	0.292	4.921	3.289	4.889e-03	0.124	-2.064	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	12	103374907	AI806905	50515	12q	Hs.17569	11	N-acetylgalactosamine 4-O-sulfotransferase activity chondrocyte development Golgi apparatus respiratory gaseous exchange post-embryonic development membrane integral to membrane carbohydrate biosynthetic process transferase activity chondroitin sulfate biosynthetic process negative regulation of transforming growth factor beta receptor signaling pathway polysaccharide localization tail morphogenesis regulation of cell proliferation embryonic digit morphogenesis negative regulation of apoptosis chondroitin 4-sulfotransferase activity developmental growth embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis cartilage development	Chondroitin sulfate biosynthesis Sulfur metabolism
222899_at	0.302	4.932	3.289	4.894e-03	0.124	-2.065	ITGA11	integrin, alpha 11	15	-66381095	AF109681	22801	15q23	Hs.436416	12	magnesium ion binding receptor activity calcium ion binding collagen binding substrate-bound cell migration cell adhesion cell-matrix adhesion integrin-mediated signaling pathway muscle organ development integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
218954_s_at	-0.499	6.227	-3.289	4.896e-03	0.124	-2.065	BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	8	-37820560	AF298153	55290	8p11.23	Hs.709301	11	protein binding nucleus transcription factor complex transcription initiation regulation of transcription, DNA-dependent zinc ion binding transcription regulator activity metal ion binding
208643_s_at	-0.372	8.176	-3.289	4.896e-03	0.124	-2.065	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	2	216682264	J04977	7520	2q35	Hs.388739	148	nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding promoter binding hydrolase activity provirus integration initiation of viral infection	Non-homologous end-joining
227968_at	0.313	6.391	3.289	4.897e-03	0.124	-2.065	PDDC1	Parkinson disease 7 domain containing 1	11	-757222	AI139988	347862	11p15.5	Hs.218362	4	extracellular region
221195_at	-0.442	4.261	-3.287	4.912e-03	0.124	-2.068	RNFT1	ring finger protein, transmembrane 1	17	-55384504	NM_016125	51136	17q23.1	Hs.531701	1	protein binding zinc ion binding membrane integral to membrane metal ion binding
225442_at	0.418	6.635	3.287	4.912e-03	0.124	-2.068	DDR2	discoidin domain receptor tyrosine kinase 2	1	160868851	AI799915	4921	1q23.3	Hs.275757 Hs.593833	26	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation cell adhesion signal transduction transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell proliferation membrane transferase activity
218656_s_at	0.397	7.726	3.286	4.922e-03	0.124	-2.070	LHFP	lipoma HMGIC fusion partner	13	-38815028	NM_005780	10186	13q12	Hs.507798	8	DNA binding membrane integral to membrane
208557_at	0.412	5.361	3.285	4.931e-03	0.124	-2.072	HOXA6	homeobox A6	7	-27151640	NM_024014	3203	7p15-p14	Hs.679517	12	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation sequence-specific DNA binding embryonic skeletal system morphogenesis
221280_s_at	-0.449	5.421	-3.284	4.941e-03	0.124	-2.074	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	NM_019619	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
225355_at	0.521	7.699	3.284	4.942e-03	0.124	-2.074	NEURL1B	neuralized homolog 1B (Drosophila)	5	172000880	AK026748	54492	5q35.1	Hs.91521	3	protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
213502_x_at	0.319	6.052	3.284	4.942e-03	0.124	-2.074	LOC91316	glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene	22	-22310675	AA398569	91316	22q11.23	Hs.148656	4
200086_s_at	0.374	11.778	3.283	4.951e-03	0.124	-2.076	COX4I1	cytochrome c oxidase subunit IV isoform 1	16	84390696	AA854966	1327	16q22-qter	Hs.433419	17	cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
1554029_a_at	-0.469	2.907	-3.282	4.967e-03	0.125	-2.078	TTC37	tetratricopeptide repeat domain 37	5	-94825877	BC030966	9652	5q15	Hs.482868	4	binding	RNA degradation
201543_s_at	0.342	7.255	3.281	4.969e-03	0.125	-2.079	SAR1A	SAR1 homolog A (S. cerevisiae)	10	-71579973	NM_020150	56681	10q22.1	Hs.499960 Hs.594910	13	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport vesicle-mediated transport sarcoplasmic reticulum
1552562_at	0.314	4.198	3.281	4.972e-03	0.125	-2.080	ZNF570	zinc finger protein 570	19	42651821	NM_144694	148268	19q13.12	Hs.350875	1	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229517_at	0.442	5.782	3.280	4.985e-03	0.125	-2.082	PTPDC1	protein tyrosine phosphatase domain containing 1	9	95832896, 95886566	BE046919	138639	9q22.32	Hs.437943	2	protein tyrosine phosphatase activity protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity
233990_at	-0.236	3.948	-3.280	4.986e-03	0.125	-2.082	C19orf61	chromosome 19 open reading frame 61	19	-48927140	AK022948	56006	19q13.31	Hs.466875	7	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein binding intracellular
229588_at	-0.567	3.614	-3.279	4.992e-03	0.125	-2.083	DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	2	183289243	AA651899	54431	2q32.1	Hs.516632	13	extracellular region endoplasmic reticulum endoplasmic reticulum lumen protein folding heat shock protein binding cell redox homeostasis unfolded protein binding
1555971_s_at	-0.383	7.134	-3.279	4.996e-03	0.125	-2.084	FBXO28	F-box protein 28	1	222368413	AU154086	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
211964_at	0.772	8.145	3.277	5.014e-03	0.125	-2.087	COL4A2	collagen, type IV, alpha 2	13	109757631	X05610	1284	13q34	Hs.508716	54	extracellular matrix structural constituent binding extracellular region collagen collagen type IV negative regulation of angiogenesis extracellular matrix organization	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
226998_at	-0.441	7.112	-3.276	5.021e-03	0.125	-2.089	NARG1	NMDA receptor regulated 1	4	140442125	AL556909	80155	4q31.1	Hs.715706	17	angiogenesis protein binding nucleus transcription factor complex cytoplasm N-terminal protein amino acid acetylation multicellular organismal development N-acetyltransferase activity cell differentiation ribosome binding regulation of transcription positive regulation of transcription, DNA-dependent
209492_x_at	0.374	11.523	3.276	5.026e-03	0.125	-2.089	ATP5I	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E	4	-656224	BC003679	521	4p16.3	Hs.85539	14	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
1557331_at	-0.286	4.699	-3.276	5.026e-03	0.125	-2.089	POLR1B	polymerase (RNA) I polypeptide B, 128kDa	2	113015962	CA442932	84172	2q13	Hs.86337	21	DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm nucleolus transcription zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
208576_s_at	0.266	2.804	3.275	5.032e-03	0.125	-2.091	HIST1H3B	histone cluster 1, H3b	6	-26139795	NM_003537	8358	6p21.3	Hs.533292	40		Systemic lupus erythematosus
224298_s_at	-0.442	7.624	-3.275	5.033e-03	0.125	-2.091	UBAC2	UBA domain containing 2	13	98650679, 98651163	BC004528	337867	13q32.3	Hs.508545	6	membrane integral to membrane
243045_at	0.460	7.291	3.275	5.033e-03	0.125	-2.091	SMYD1	SET and MYND domain containing 1	2	88148496	N75296	150572	2p11.2	Hs.516176	8	DNA binding nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding
202341_s_at	0.332	5.699	3.274	5.041e-03	0.126	-2.092	TRIM2	tripartite motif-containing 2	4	154293719, 154345047	AA149745	23321	4q31.3	Hs.435711	6	protein binding intracellular cytoplasm biological_process zinc ion binding metal ion binding
215211_at	0.367	5.517	3.274	5.044e-03	0.126	-2.093	LOC730092	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene	16	-21715451	AF054994	730092	16p12.2	Hs.31290 Hs.348979 Hs.658149	4
221019_s_at	0.570	6.313	3.274	5.048e-03	0.126	-2.094	COLEC12	collectin sub-family member 12	18	-309355	NM_030781	81035	18pter-p11.3	Hs.464422	8	scavenger receptor activity binding calcium ion binding sugar binding galactose binding phagocytosis, recognition pattern recognition receptor activity carbohydrate mediated signaling membrane integral to membrane low-density lipoprotein binding innate immune response protein homooligomerization
201064_s_at	-0.416	9.863	-3.273	5.052e-03	0.126	-2.094	PABPC4	poly(A) binding protein, cytoplasmic 4 (inducible form)	1	-39799071	NM_003819	8761	1p32-p36	Hs.169900	17	nucleotide binding RNA binding protein binding cytoplasm RNA processing RNA catabolic process translation blood coagulation poly(A) RNA binding poly(U) RNA binding poly(C) RNA binding
223537_s_at	0.305	5.167	3.273	5.052e-03	0.126	-2.094	WNT5B	wingless-type MMTV integration site family, member 5B	12	1596482, 1608672	AW007350	81029	12p13.3	Hs.306051	11	signal transducer activity extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
225379_at	-0.381	8.104	-3.273	5.053e-03	0.126	-2.094	MAPT	microtubule-associated protein tau	17	41327543	AA199717	4137	17q21.1	Hs.101174	545	microtubule cytoskeleton organization microtubule cytoskeleton organization structural constituent of cytoskeleton cytoplasm cytosol cytoskeleton microtubule microtubule associated complex plasma membrane plasma membrane negative regulation of microtubule depolymerization microtubule binding microtubule binding lipoprotein binding SH3 domain binding enzyme binding axon axon growth cone growth cone positive regulation of microtubule polymerization positive regulation of microtubule polymerization apolipoprotein E binding identical protein binding cell projection tubulin complex tubulin complex positive regulation of axon extension positive regulation of axon extension generation of neurons	MAPK signaling pathway Alzheimer's disease
215933_s_at	0.521	3.972	3.272	5.064e-03	0.126	-2.096	HHEX	hematopoietically expressed homeobox	10	94439660	Z21533	3087	10q23.33	Hs.118651	86	liver development transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent mRNA export from nucleus cell cycle multicellular organismal development transcription factor binding eukaryotic initiation factor 4E binding organ morphogenesis anterior/posterior pattern formation positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter negative regulation of angiogenesis transcription repressor activity cell differentiation positive regulation of Wnt receptor signaling pathway thyroid gland development forebrain development negative regulation of vascular endothelial growth factor receptor signaling pathway embryonic heart tube development regulation of cell proliferation sequence-specific DNA binding	Maturity onset diabetes of the young
232358_at	0.245	5.943	3.272	5.066e-03	0.126	-2.097	KIAA1328	KIAA1328	18	32663077	AB037749	57536	18q12.2	Hs.4045	7
216120_s_at	-1.004	4.886	-3.271	5.075e-03	0.126	-2.098	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	3	-10340706	X63575	491	3p25.3	Hs.268942	30	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding cytoplasm plasma membrane ATP biosynthetic process cation transport calcium ion transport sensory perception of sound metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances neuron differentiation	Calcium signaling pathway
220936_s_at	0.431	4.046	3.271	5.076e-03	0.126	-2.099	H2AFJ	H2A histone family, member J	12	14818536, 14818536	NM_018267	55766	12p12	Hs.524280 Hs.718660	11	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
201314_at	-0.441	8.009	-3.271	5.077e-03	0.126	-2.099	STK25	serine/threonine kinase 25 (STE20 homolog, yeast)	2	-242083104	NM_006374	10494	2q37.3	Hs.516807	12	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus protein amino acid phosphorylation response to oxidative stress signal transduction transferase activity identical protein binding
222146_s_at	0.305	8.005	3.271	5.079e-03	0.126	-2.099	TCF4	transcription factor 4	18	-51040559	AK026674	6925	18q21.1	Hs.605153	55	transcription factor activity protein binding nucleus regulation of transcription positive regulation of transcription, DNA-dependent protein heterodimerization activity
228976_at	0.448	5.536	3.271	5.080e-03	0.126	-2.099	ICOSLG	inducible T-cell co-stimulator ligand	21	-44471149	AA778249	23308	21q22.3	Hs.14155	29	receptor binding defense response immune response hyperosmotic response signal transduction membrane integral to membrane positive regulation of activated T cell proliferation T cell activation B cell activation	Cell adhesion molecules (CAMs)
217118_s_at	-0.911	6.156	-3.271	5.081e-03	0.126	-2.100	C22orf9	chromosome 22 open reading frame 9	22	-43966786, -43966786	AK025608	23313	22q13.31	Hs.592207	10	protein binding
201408_at	-0.620	9.614	-3.270	5.092e-03	0.126	-2.101	PPP1CB	protein phosphatase 1, catalytic subunit, beta isoform	2	28828117, 28828129	W67887	5500	2p23	Hs.591571 Hs.702907	42	protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding cell division MLL5-L complex	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton Insulin signaling pathway
201351_s_at	-0.456	8.669	-3.270	5.092e-03	0.126	-2.102	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AF070656	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
208002_s_at	0.348	4.767	3.269	5.099e-03	0.126	-2.103	ACOT7	acyl-CoA thioesterase 7	1	-6246918, -6246918, -6246918, -6246918	NM_007274	11332	1p36.31-p36.11	Hs.126137	11	acyl-CoA binding carboxylesterase activity cytoplasm mitochondrion lipid metabolic process palmitoyl-CoA hydrolase activity hydrolase activity	Biosynthesis of unsaturated fatty acids
221024_s_at	0.463	3.849	3.268	5.104e-03	0.126	-2.104	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10	20	44771685	NM_030777	81031	20q13.1	Hs.305971	18	transporter activity sugar:hydrogen symporter activity cytoplasm carbohydrate transport glucose transport membrane integral to membrane substrate-specific transmembrane transporter activity perinuclear region of cytoplasm transmembrane transport
209657_s_at	-0.685	8.384	-3.268	5.104e-03	0.126	-2.104	HSF2	heat shock transcription factor 2	6	122762394	M65217	3298	6q22.31	Hs.158195	28	transcription factor activity transcription coactivator activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress spermatogenesis protein homodimerization activity sequence-specific DNA binding
205981_s_at	-0.739	6.685	-3.268	5.105e-03	0.126	-2.104	ING2	inhibitor of growth family, member 2	4	184663213	NM_001564	3622	4q35.1	Hs.107153	27	DNA binding chromatin binding protein binding nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding transcription activator activity chromatin modification Sin3 complex CCAAT-binding factor complex regulation of growth positive regulation of transcription metal ion binding
244623_at	-1.499	7.440	-3.268	5.111e-03	0.126	-2.105	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5	6	73388291	BF513800	56479	6q14	Hs.445324 Hs.675919	15	inward rectifier potassium channel activity voltage-gated ion channel activity protein complex assembly ion transport potassium ion transport synaptic transmission voltage-gated potassium channel complex membrane integral to membrane potassium ion binding
208616_s_at	-0.532	10.542	-3.267	5.121e-03	0.126	-2.107	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	U48297	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
227758_at	0.453	5.636	3.266	5.131e-03	0.126	-2.108	RERG	RAS-like, estrogen-regulated, growth inhibitor	12	-15151983	AW294092	85004	12p12.3	Hs.199487	4	nucleotide binding GTPase activity GTP binding intracellular nucleus cytoplasm cytosol small GTPase mediated signal transduction negative regulation of cell proliferation response to hormone stimulus GDP binding negative regulation of cell growth estrogen receptor binding
41512_at	-0.551	6.164	-3.265	5.135e-03	0.126	-2.109	BRAP	BRCA1 associated protein	12	-110564332	AL042733	8315	12q24	Hs.530940	12	ubiquitin-protein ligase activity cytoplasm zinc ion binding negative regulation of signal transduction ligase activity modification-dependent protein catabolic process identical protein binding metal ion binding
207226_at	0.367	4.999	3.265	5.136e-03	0.126	-2.109	HIST1H2BN	histone cluster 1, H2bn	6	27914418	NM_003520	8341	6p22-p21.3	Hs.534368 Hs.673851	18	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
226326_at	-0.500	7.696	-3.264	5.146e-03	0.127	-2.111	PCGF5	polycomb group ring finger 5	10	92970348	AI798098	84333	10q23.32	Hs.500512	9	protein binding centrosome zinc ion binding regulation of transcription metal ion binding
201260_s_at	-0.619	9.542	-3.264	5.147e-03	0.127	-2.111	SYPL1	synaptophysin-like 1	7	-105518187, -105518187	NM_006754	6856	7q22.3	Hs.80919	13	transporter activity integral to plasma membrane transport synaptic transmission synaptic vesicle membrane secretory granule cytoplasmic vesicle melanosome
230285_at	-0.453	5.014	-3.264	5.155e-03	0.127	-2.113	SVIP	small VCP/p97-interacting protein	11	-22800173	BF447829	258010	11p14.2	Hs.349096	4	endoplasmic reticulum Golgi apparatus plasma membrane
208266_at	0.335	4.306	3.263	5.165e-03	0.127	-2.115	C8orf17	chromosome 8 open reading frame 17	8		NM_020237	56988	8q24.3	Hs.283098	2	cytoplasm endoplasmic reticulum endoplasmic reticulum membrane microsome membrane
1553101_a_at	-0.524	8.478	-3.262	5.170e-03	0.127	-2.116	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)	17	18027591	NM_017758	54890	17p11.2	Hs.462392	5	membrane integral to membrane
203658_at	0.799	8.529	3.261	5.180e-03	0.127	-2.117	SLC25A20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	3	-48869359	BC001689	788	3p21.31	Hs.13845	19	transporter activity binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane transport carnitine shuttle acyl carnitine transporter activity membrane integral to membrane regulation of fatty acid oxidation
214314_s_at	-0.371	6.510	-3.261	5.182e-03	0.127	-2.118	EIF5B	eukaryotic translation initiation factor 5B	2	99320265	BE138647	9669	2q11.2	Hs.158688	15	nucleotide binding translation initiation factor activity translation initiation factor activity GTPase activity protein binding GTP binding cytoplasm translation regulation of translational initiation regulation of translational initiation
227945_at	-0.827	7.217	-3.261	5.187e-03	0.127	-2.119	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	BE882538	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
208841_s_at	-0.614	9.625	-3.261	5.188e-03	0.127	-2.119	G3BP2	GTPase activating protein (SH3 domain) binding protein 2	4	-76786976, -76786976	AB014560	9908	4q21.1	Hs.303676	15	nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport
243344_at	0.304	5.288	3.260	5.190e-03	0.127	-2.119	LOC100130054	hypothetical LOC100130054	9		BE218142	100130054	9q21.12	Hs.207074
201088_at	-0.764	7.145	-3.260	5.192e-03	0.127	-2.119	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	17	63462309, -1713110	NM_002266	3838	17q24.2	Hs.594238	125	regulation of DNA recombination M phase specific microtubule process G2 phase of mitotic cell cycle protein binding nucleus nuclear pore nucleoplasm cytoplasm DNA metabolic process NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
235195_at	-0.680	5.787	-3.260	5.193e-03	0.127	-2.120	FBXW2	F-box and WD repeat domain containing 2	9	-122559074	BG109988	26190	9q34	Hs.494985	12	ubiquitin-protein ligase activity protein binding cytoplasm protein modification process proteolysis modification-dependent protein catabolic process
213616_at	0.279	4.239	3.260	5.196e-03	0.127	-2.120	C18orf10	chromosome 18 open reading frame 10	18	-32630031	BF063896	25941	18q12.2	Hs.695999	5	cytoplasm cytoskeleton microtubule
209943_at	-0.880	5.450	-3.259	5.204e-03	0.127	-2.122	FBXL4	F-box and leucine-rich repeat protein 4	6	-99428321	AF176699	26235	6q16.1-q16.3	Hs.536850	6	ubiquitin ligase complex nucleus cytoplasm ubiquitin-dependent protein catabolic process
205909_at	0.420	4.225	3.259	5.207e-03	0.127	-2.122	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)	14	-49180028	NM_002692	5427	14q21-q22	Hs.162777	14	DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm DNA-dependent DNA replication DNA repair nucleotide-excision repair, DNA gap filling transferase activity nucleotidyltransferase activity	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
225210_s_at	-0.437	8.367	-3.257	5.222e-03	0.127	-2.125	FAM103A1	family with sequence similarity 103, member A1	15	81445998	AW025216	83640	15q25.2	Hs.80624	3
221966_at	0.422	6.492	3.257	5.222e-03	0.127	-2.125	GPR137	G protein-coupled receptor 137	11	63809906	AA813194	56834	11cen-q22.3	Hs.523763	4	membrane integral to membrane
223124_s_at	-0.424	8.444	-3.257	5.224e-03	0.127	-2.125	C1orf128	chromosome 1 open reading frame 128	1	23977462	AF271784	57095	1p36.11	Hs.31819	4
204194_at	-0.677	5.949	-3.257	5.225e-03	0.127	-2.125	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	21	29593090, 29593607, 29599430	NM_001186	571	21q22.11	Hs.154276	30	transcription factor activity nucleus nucleolus cytosol regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity
223451_s_at	0.505	6.374	3.257	5.228e-03	0.127	-2.126	CKLF	chemokine-like factor	16	65143966, 65143972	AF096895	51192	16q21	Hs.15159 Hs.710181	12	extracellular region extracellular space chemotaxis chemokine activity cell proliferation membrane integral to membrane neutrophil chemotaxis secretion by cell macrophage chemotaxis lymphocyte chemotaxis
200732_s_at	-0.582	10.872	-3.257	5.228e-03	0.127	-2.126	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	AL578310	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
214669_x_at	0.461	5.412	3.256	5.233e-03	0.127	-2.127	IGKC	immunoglobulin kappa constant	2		BG485135	3514	2p12	Hs.449621 Hs.703932	31	antigen binding protein binding extracellular region extracellular region immune response
1558077_s_at	0.268	4.430	3.256	5.238e-03	0.127	-2.128	MDH1B	malate dehydrogenase 1B, NAD (soluble)	2	-207310733	BG202523	130752	2q33.3	Hs.147816	1	binding carbohydrate metabolic process tricarboxylic acid cycle malate metabolic process oxidoreductase activity malate dehydrogenase activity oxidation reduction
211748_x_at	0.891	9.220	3.255	5.243e-03	0.127	-2.128	PTGDS	prostaglandin D2 synthase 21kDa (brain)	9	138991776	BC005939	5730	9q34.2-q34.3	Hs.446429	63	prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm	Arachidonic acid metabolism Metabolic pathways
218552_at	0.430	8.683	3.254	5.253e-03	0.127	-2.130	ECHDC2	enoyl Coenzyme A hydratase domain containing 2	1	-53134491	NM_018281	55268	1p32.3	Hs.476319	2	mitochondrion lipid metabolic process fatty acid metabolic process metabolic process lyase activity
222292_at	0.252	3.560	3.254	5.254e-03	0.127	-2.130	CD40	CD40 molecule, TNF receptor superfamily member 5	20	44180312	AW298127	958	20q12-q13.2	Hs.472860	290	receptor activity extracellular region plasma membrane plasma membrane integral to plasma membrane protein complex assembly inflammatory response enzyme binding platelet activation B cell proliferation positive regulation of I-kappaB kinase/NF-kappaB cascade	Cytokine-cytokine receptor interaction Cell adhesion molecules (CAMs) Toll-like receptor signaling pathway Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Primary immunodeficiency
219187_at	-0.245	5.713	-3.254	5.257e-03	0.127	-2.131	FKBPL	FK506 binding protein like	6	-32204461, -3503650	NM_022110	63943	6p21.3	Hs.520042	7	binding cellular_component extracellular space protein folding JAK-STAT cascade nervous system development brain development aging response to radiation basal plasma membrane positive regulation of smooth muscle cell proliferation advanced glycation end-product receptor activity
212738_at	0.312	5.907	3.254	5.259e-03	0.127	-2.131	ARHGAP19	Rho GTPase activating protein 19	10	-98971919	AV717623	84986	10q24.1	Hs.80305	8	GTPase activator activity intracellular nucleus signal transduction
226196_s_at	0.278	6.218	3.253	5.264e-03	0.127	-2.132	C14orf179	chromosome 14 open reading frame 179	14	75521848	AW827281	112752	14q24.3	Hs.532626	5
1569128_at	-0.239	2.412	-3.253	5.265e-03	0.127	-2.132	C3orf38	chromosome 3 open reading frame 38	3	88281582	BC016013	285237	3p11.1	Hs.476944 Hs.518099	2	apoptosis
223175_s_at	-0.580	10.444	-3.253	5.266e-03	0.127	-2.133	FEM1A	fem-1 homolog a (C. elegans)	19	4742727	BC004988	55527	19p13.3	Hs.515082	9	ubiquitin-protein ligase activity cytoplasm modification-dependent protein catabolic process regulation of ubiquitin-protein ligase activity
1554452_a_at	0.384	5.420	3.253	5.267e-03	0.127	-2.133	C7orf68	chromosome 7 open reading frame 68	7	127883119	BC001863	29923	7q32.1	Hs.710088	9	molecular_function cellular_component response to stress membrane integral to membrane
219400_at	0.280	5.054	3.253	5.273e-03	0.127	-2.134	CNTNAP1	contactin associated protein 1	17	38088157	NM_003632	8506	17q21	Hs.408730	10	receptor activity SH3/SH2 adaptor activity receptor binding integral to plasma membrane cell adhesion signal transduction membrane SH3 domain binding paranode region of axon	Cell adhesion molecules (CAMs)
225987_at	0.663	7.319	3.252	5.277e-03	0.127	-2.134	STEAP4	STEAP family member 4	7	-87743679	AA650281	79689	7q21.12	Hs.521008	7	binding iron ion binding copper ion binding Golgi apparatus plasma membrane ion transport iron ion transport electron carrier activity integral to membrane oxidoreductase activity fat cell differentiation metal ion binding FAD binding oxidation reduction
217712_at	0.264	2.135	3.252	5.279e-03	0.127	-2.135	LOC389906	similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1)	X		AA479678	389906	Xp22.33	Hs.636199 Hs.684492	1
235616_at	0.317	4.398	3.252	5.284e-03	0.127	-2.136	TSHZ2	teashirt zinc finger homeobox 2	20	51022283	AI694059	128553	20q13.2	Hs.271605 Hs.473117 Hs.649877	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding
203862_s_at	-0.658	11.013	-3.251	5.288e-03	0.127	-2.136	ACTN2	actinin, alpha 2	1	234916392	H16245	88	1q42-q43	Hs.498178	57	actin binding integrin binding calcium ion binding nucleolus cytoplasm cytoskeleton actin filament focal adhesion muscle contraction cell adhesion structural constituent of muscle Z disc microspike assembly filopodium thyroid hormone receptor coactivator activity pseudopodium titin binding identical protein binding regulation of apoptosis dendritic spine protein dimerization activity focal adhesion formation protein homotetramerization ZASP binding FATZ 1 binding titin Z domain binding	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212686_at	0.875	4.046	3.251	5.296e-03	0.128	-2.138	PPM1H	protein phosphatase 1H (PP2C domain containing)	12	-61324030	AB032983	57460	12q14.1-q14.2	Hs.435479	5	phosphoprotein phosphatase activity hydrolase activity
228256_s_at	0.428	5.578	3.250	5.297e-03	0.128	-2.138	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A	5	-111526213	AU144565	64097	5q22.1-q22.2	Hs.584954	7	binding cellular_component cytoplasm cytoskeleton cytoskeletal protein binding biological_process extrinsic to membrane
225806_at	0.530	3.152	3.250	5.301e-03	0.128	-2.139	JUB	jub, ajuba homolog (Xenopus laevis)	14	-22510249, -22510249	AI289311	84962	14q11.2	Hs.655832	16	protein binding nucleus cytoplasm centrosome cytoskeleton plasma membrane focal adhesion cell cycle cell adhesion zinc ion binding lamellipodium lamellipodium assembly cell junction regulation of cell migration wound healing, spreading of epidermal cells regulation of GTPase activity metal ion binding focal adhesion formation
1557165_s_at	0.680	8.697	3.249	5.313e-03	0.128	-2.141	KLHL18	kelch-like 18 (Drosophila)	3	47299333	BM141828	23276	3p21.31	Hs.517946	8	protein binding
225626_at	0.629	5.361	3.248	5.319e-03	0.128	-2.142	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	8	-82042600	AK000680	55824	8q21.13	Hs.266175	14	SH3/SH2 adaptor activity protein binding plasma membrane plasma membrane immune response intracellular signaling cascade integral to membrane SH2 domain binding membrane raft negative regulation of T cell activation
212187_x_at	0.904	8.867	3.248	5.327e-03	0.128	-2.143	PTGDS	prostaglandin D2 synthase 21kDa (brain)	9	138991776	NM_000954	5730	9q34.2-q34.3	Hs.446429	63	prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm	Arachidonic acid metabolism Metabolic pathways
243318_at	-0.349	6.640	-3.247	5.332e-03	0.128	-2.144	DCAF8	DDB1 and CUL4 associated factor 8	1	-158475636, -158475636, -158452128, -158452128	AI208342	50717	1q22-q23	Hs.632447	10	protein binding
232524_x_at	-0.381	6.754	-3.247	5.337e-03	0.128	-2.145	ANAPC4	anaphase promoting complex subunit 4	4	24987945	AK001881	29945	4p15.2	Hs.152173	21	G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
204274_at	-0.405	9.014	-3.246	5.342e-03	0.128	-2.146	EBAG9	estrogen receptor binding site associated, antigen, 9	8	110621104, 110621485	AA812215	9166	8q23	Hs.409368	55	regulation of cell growth soluble fraction Golgi apparatus plasma membrane focal adhesion apoptosis integral to membrane apoptotic protease activator activity
202303_x_at	-0.476	5.846	-3.246	5.345e-03	0.128	-2.146	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	NM_003601	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
203450_at	0.322	7.581	3.245	5.352e-03	0.128	-2.147	CBY1	chibby homolog 1 (Drosophila)	22	37382603	NM_015373	25776	22q12	Hs.334911 Hs.596584	20	nucleus Golgi apparatus trans-Golgi network beta-catenin binding protein localization nuclear speck negative regulation of Wnt receptor signaling pathway negative regulation of Wnt receptor signaling pathway identical protein binding fat cell differentiation negative regulation of transcription, DNA-dependent cardiac muscle cell differentiation
236247_at	0.289	5.933	3.244	5.365e-03	0.128	-2.150	NSUN4	NOL1/NOP2/Sun domain family, member 4	1	46578976	AI536692	387338	1p34	Hs.163424	4	methyltransferase activity transferase activity
243108_at	-0.360	3.464	-3.244	5.368e-03	0.128	-2.150	RANBP9	RAN binding protein 9	6	-13729708	AW297762	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
230009_at	-0.463	6.502	-3.243	5.376e-03	0.128	-2.152	FAM118B	family with sequence similarity 118, member B	11	125586828	AI936072	79607	11q24.2	Hs.276315	2
225240_s_at	-0.506	7.880	-3.243	5.378e-03	0.128	-2.152	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BE220026	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
203824_at	-2.048	8.236	-3.243	5.380e-03	0.128	-2.152	TSPAN8	tetraspanin 8	12	-69805143	NM_004616	7103	12q14.1-q21.1	Hs.170563	23	signal transducer activity lysosome protein amino acid glycosylation membrane integral to membrane
210007_s_at	-0.521	4.688	-3.243	5.381e-03	0.128	-2.152	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	2	157000210, 157001145	U36310	2820	2q24.1	Hs.512382	20	glycerol-3-phosphate dehydrogenase activity calcium ion binding mitochondrion mitochondrial inner membrane glycerol-3-phosphate metabolic process gluconeogenesis glycerol-3-phosphate dehydrogenase complex oxidoreductase activity oxidation reduction	Glycerophospholipid metabolism
201843_s_at	0.876	4.757	3.242	5.384e-03	0.128	-2.153	EFEMP1	EGF-containing fibulin-like extracellular matrix protein 1	2	-55946605, -55946605	NM_004105	2202	2p16	Hs.76224	31	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix visual perception
209124_at	0.397	6.129	3.242	5.387e-03	0.128	-2.154	MYD88	myeloid differentiation primary response gene (88)	3	38154972	U70451	4615	3p22	Hs.82116	98	response to molecule of fungal origin MyD88-dependent toll-like receptor signaling pathway transmembrane receptor activity Toll binding death receptor binding protein binding cytoplasm inflammatory response Toll signaling pathway response to virus immunoglobulin mediated immune response cytokine-mediated signaling pathway intrinsic to membrane lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide positive regulation of tumor necrosis factor production regulation of cell proliferation positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of chemokine biosynthetic process innate immune response type I interferon biosynthetic process positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade positive regulation of smooth muscle cell proliferation positive regulation of NF-kappaB transcription factor activity	Apoptosis Toll-like receptor signaling pathway
240728_at	0.268	4.796	3.242	5.394e-03	0.128	-2.155	PLCB4	phospholipase C, beta 4	20	9024931	AI224105	5332	20p12	Hs.472101	17	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding intracellular signaling cascade lipid catabolic process hydrolase activity	Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease
222997_s_at	0.459	8.468	3.242	5.395e-03	0.128	-2.155	MRPS21	mitochondrial ribosomal protein S21	1	148532892	BC004566	54460	1q21	Hs.405880	8	structural constituent of ribosome intracellular mitochondrion mitochondrial small ribosomal subunit ribosome translation
200602_at	0.501	7.371	3.241	5.399e-03	0.128	-2.156	APP	amyloid beta (A4) precursor protein	21	-26174732	NM_000484	351	21q21.2 21q21.3	Hs.434980	835	serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity iron ion binding copper ion binding extracellular region extracellular region cytoplasm Golgi apparatus plasma membrane integral to plasma membrane coated pit cellular copper ion homeostasis endocytosis cell adhesion Notch signaling pathway heparin binding cell death zinc ion binding cell surface peptidase inhibitor activity platelet alpha granule lumen acetylcholine receptor binding identical protein binding metal ion binding neuromuscular process neuron apoptosis	Alzheimer's disease
212431_at	0.307	7.127	3.241	5.404e-03	0.128	-2.156	HMGXB3	HMG box domain containing 3	5	149360361	D83778	22993	5q32	Hs.719189	8	DNA binding cellular_component nucleus nucleolus biological_process kinase activity
202738_s_at	-0.724	8.619	-3.241	5.405e-03	0.128	-2.157	PHKB	phosphorylase kinase, beta	16	46052710	BG149218	5257	16q12-q13	Hs.78060	13	catalytic activity calmodulin binding plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy	Calcium signaling pathway Insulin signaling pathway
224937_at	0.718	4.284	3.240	5.410e-03	0.128	-2.157	PTGFRN	prostaglandin F2 receptor negative regulator	1	117254211	BF311866	5738	1p13.1	Hs.418093	14	protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane
206167_s_at	-0.906	7.674	-3.240	5.411e-03	0.128	-2.158	ARHGAP6	Rho GTPase activating protein 6	X	-11071437, -11065583, -11065583	NM_001174	395	Xp22.3	Hs.435291	6	SH3/SH2 adaptor activity GTPase activator activity Rho GTPase activator activity intracellular cytoplasm actin filament actin filament organization signal transduction Rho protein signal transduction SH3 domain binding actin filament polymerization regulation of GTPase activity negative regulation of stress fiber formation negative regulation of focal adhesion formation
201535_at	-0.448	9.068	-3.240	5.412e-03	0.128	-2.158	UBL3	ubiquitin-like 3	13	-29236545	NM_007106	5412	13q12-q13	Hs.145575	12	intracellular plasma membrane
224874_at	-0.497	7.384	-3.240	5.415e-03	0.128	-2.158	POLR1D	polymerase (RNA) I polypeptide D, 16kDa	13	27094002, 27094028	N32181	51082	13q12.2	Hs.507584	15	DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm transcription protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
238337_s_at	-0.490	8.666	-3.240	5.415e-03	0.128	-2.158	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	5	34965454	BF678298	134218	5p13.2	Hs.131887	5	nucleic acid binding intracellular zinc ion binding heat shock protein binding metal ion binding
205898_at	0.713	6.220	3.240	5.416e-03	0.128	-2.158	CX3CR1	chemokine (C-X3-C motif) receptor 1	3	-39279988	U20350	1524	3p21 3p21.3	Hs.78913	123	receptor activity G-protein coupled receptor activity chemokine receptor activity protein binding plasma membrane integral to plasma membrane chemotaxis cellular defense response cell adhesion signal transduction G-protein coupled receptor protein signaling pathway response to wounding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway
209138_x_at	0.722	4.901	3.239	5.420e-03	0.128	-2.159	IGL@	immunoglobulin lambda locus	22		M87790	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
230000_at	-0.420	4.654	-3.239	5.422e-03	0.128	-2.159	RNF213	ring finger protein 213	17	75928320	AI523817	57674	17q25.3	Hs.195642 Hs.657519	6	nucleotide binding protein binding zinc ion binding nucleoside-triphosphatase activity metal ion binding
227646_at	0.557	6.777	3.239	5.426e-03	0.129	-2.160	EBF1	early B-cell factor 1	5	-158055500	BG435302	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
228163_at	0.281	5.676	3.238	5.431e-03	0.129	-2.161	ST6GALNAC4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	9	-129709985	BE858453	27090	9q34	Hs.3972 Hs.709827	13	soluble fraction nucleus Golgi apparatus protein amino acid glycosylation glycolipid metabolic process membrane integral to membrane integral to Golgi membrane (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	Glycosphingolipid biosynthesis - ganglio series Metabolic pathways
210938_at	0.418	4.491	3.238	5.438e-03	0.129	-2.162	PDX1	pancreatic and duodenal homeobox 1	13	27392167	U30329	3651	13q12.1	Hs.32938	86	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity protein binding nucleus glucose metabolic process generation of precursor metabolites and energy nitric oxide mediated signal transduction multicellular organismal development positive regulation of cell proliferation negative regulation of cell proliferation organ morphogenesis morphogenesis of embryonic epithelium transcription activator activity insulin secretion cell differentiation exocrine pancreas development endocrine pancreas development glucose homeostasis sequence-specific DNA binding intracellular part positive regulation of transcription from RNA polymerase II promoter	Type II diabetes mellitus Maturity onset diabetes of the young
201311_s_at	0.459	6.204	3.238	5.438e-03	0.129	-2.162	SH3BGRL	SH3 domain binding glutamic acid-rich protein like	X	80343958	AL515318	6451	Xq13.3	Hs.108029	13	SH3/SH2 adaptor activity nucleus cytoplasm SH3 domain binding
214884_at	-0.247	3.183	-3.237	5.441e-03	0.129	-2.163	MCF2	MCF.2 cell line derived transforming sequence	X	-138491595, -138491595	AL033403	4168	Xq27	Hs.387262	24	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular membrane fraction cytoplasm cytosol cytoskeleton intracellular signaling cascade membrane regulation of Rho protein signal transduction
228039_at	-0.470	7.700	-3.237	5.447e-03	0.129	-2.164	DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	5	134122359	AI765169	9879	5q31.1	Hs.406549	9	nucleotide binding RNA binding helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing Cajal body nuclear speck hydrolase activity
235215_at	-0.406	5.609	-3.236	5.456e-03	0.129	-2.165	ERCC4	excision repair cross-complementing rodent repair deficiency, complementation group 4	16	13921514	AI694544	2072	16p13.12	Hs.567265	88	nucleotide-excision repair complex magnesium ion binding nucleotide-excision repair, DNA damage removal double-strand break repair via homologous recombination nuclear chromosome, telomeric region damaged DNA binding single-stranded DNA binding endodeoxyribonuclease activity nucleus nucleoplasm nucleotide-excision repair, DNA incision, 3'-to lesion nucleotide-excision repair, DNA incision, 5'-to lesion response to DNA damage stimulus protein C-terminus binding response to UV telomere maintenance via telomere shortening hydrolase activity negative regulation of telomere maintenance protein N-terminus binding	Nucleotide excision repair
223629_at	-0.428	4.087	-3.236	5.461e-03	0.129	-2.166	PCDHB5	protocadherin beta 5	5	140494983	BC001186	26167	5q31	Hs.119693	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion synaptic transmission synaptogenesis integral to membrane calcium-dependent cell-cell adhesion
205488_at	0.363	3.903	3.236	5.462e-03	0.129	-2.166	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	5	54434230	NM_006144	3001	5q11-q12	Hs.90708	39	immunological synapse serine-type endopeptidase activity extracellular region nucleus proteolysis apoptosis cleavage of lamin immune response peptidase activity cytolysis protein homodimerization activity	Neuroactive ligand-receptor interaction
209122_at	0.531	8.438	3.235	5.469e-03	0.129	-2.168	PLIN2	perilipin 2	9	-19105758	BC005127	123	9p22.1	Hs.3416	31	protein binding extracellular region nucleus cytoplasm endoplasmic reticulum lipid particle plasma membrane long-chain fatty acid transport lipid storage
214459_x_at	0.556	9.815	3.235	5.472e-03	0.129	-2.168	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	M12679	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
232913_at	0.260	5.067	3.234	5.475e-03	0.129	-2.168	TMED8	transmembrane emp24 protein transport domain containing 8	14	-76877866	AC007954	283578	14q24.3	Hs.200413 Hs.26403	6
209522_s_at	0.492	9.483	3.232	5.497e-03	0.129	-2.172	CRAT	carnitine acetyltransferase	9	-130896895, -130896893	BC000723	1384	9q34.1	Hs.12068	10	carnitine O-acetyltransferase activity mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum lipid metabolic process fatty acid metabolic process transport acyltransferase activity energy derivation by oxidation of organic compounds membrane transferase activity
218428_s_at	0.478	8.206	3.232	5.497e-03	0.129	-2.172	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	NM_016316	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
244783_at	-0.292	2.576	-3.232	5.498e-03	0.129	-2.172	YAF2	YY1 associated factor 2	12	-40837173	R56794	10138	12q12	Hs.708084	9	transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus zinc ion binding negative regulation of transcription positive regulation of transcription metal ion binding
227320_at	0.451	6.014	3.232	5.503e-03	0.129	-2.173	FAM101A	family with sequence similarity 101, member A	12	123339662	AW264333	144347	12q24.31	Hs.432901	3
213521_at	0.343	6.700	3.231	5.514e-03	0.129	-2.175	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	2	130830049	AW575379	26469	2q21.1	Hs.516390 Hs.591549	16	non-membrane spanning protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity
206976_s_at	-0.649	8.022	-3.231	5.516e-03	0.129	-2.175	HSPH1	heat shock 105kDa/110kDa protein 1	13	-30608762	NM_006644	10808	13q12.3	Hs.36927	25	nucleotide binding ATP binding cytoplasm response to unfolded protein
213113_s_at	0.427	5.474	3.231	5.518e-03	0.129	-2.176	SLC43A3	solute carrier family 43, member 3	11	-56931002, -56931002, -56931002	AI630178	29015	11q11	Hs.99962	4	membrane integral to membrane
203300_x_at	-0.550	8.711	-3.230	5.522e-03	0.129	-2.176	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	X	-15753849	NM_003916	8905	Xp22.2	Hs.653504 Hs.656471	21	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
226475_at	0.348	6.394	3.229	5.531e-03	0.130	-2.178	FAM118A	family with sequence similarity 118, member A	22	44083744, 44084448	AI650582	55007	22q13	Hs.265018	6	membrane integral to membrane
238529_at	0.344	4.161	3.229	5.534e-03	0.130	-2.178	LOC730631	hypothetical LOC730631	1		AA573088	730631	1q21.2	Hs.528615
209496_at	0.412	6.304	3.229	5.537e-03	0.130	-2.179	RARRES2	retinoic acid receptor responder (tazarotene induced) 2	7	-149666340	BC000069	5919	7q36.1	Hs.647064	22	retinoid metabolic process molecular_function extracellular region brown fat cell differentiation
239230_at	0.250	3.366	3.228	5.544e-03	0.130	-2.180	HES5	hairy and enhancer of split 5 (Drosophila)	1	-2450045	AW079166	388585	1p36.32	Hs.57971	12	DNA binding nucleus regulation of transcription, DNA-dependent cell adhesion multicellular organismal development nervous system development positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter cell differentiation transcription regulator activity auditory receptor cell differentiation auditory receptor cell fate determination negative regulation of neuron differentiation cell maturation regulation of neurogenesis	Notch signaling pathway
202538_s_at	-0.470	7.071	-3.228	5.545e-03	0.130	-2.180	CHMP2B	chromatin modifying protein 2B	3	87359102	NM_014043	25978	3p11.2	Hs.476930	36	intracellular cytoplasm endosome cytosol protein transport membrane protein domain specific binding	Endocytosis
203409_at	0.373	5.218	3.228	5.552e-03	0.130	-2.181	DDB2	damage-specific DNA binding protein 2, 48kDa	11	47193068	NM_000107	1643	11p12-p11	Hs.700338	52	protein polyubiquitination nucleotide-excision repair, DNA damage removal damaged DNA binding ubiquitin-protein ligase activity protein binding nucleus nucleoplasm pyrimidine dimer repair response to DNA damage stimulus response to UV modification-dependent protein catabolic process protein complex protein autoubiquitination	Nucleotide excision repair p53 signaling pathway Ubiquitin mediated proteolysis
203661_s_at	-0.417	8.860	-3.228	5.553e-03	0.130	-2.181	TMOD1	tropomodulin 1	9	99326257	BC002660	7111	9q22.3	Hs.494595	18	actin binding tropomyosin binding nucleus cytoplasm membrane myofibril myofibril assembly cortical cytoskeleton
224525_s_at	-0.859	5.580	-3.228	5.553e-03	0.130	-2.182	OLA1	Obg-like ATPase 1	2	-174645420	AL136546	29789	2q31.1	Hs.157351	11	nucleotide binding protein binding ATP binding GTP binding intracellular cytoplasm ATP catabolic process hydrolase activity
202555_s_at	0.720	6.203	3.227	5.554e-03	0.130	-2.182	MYLK	myosin light chain kinase	3	-124813832, -124813832	NM_005965	4638	3q21	Hs.477375	56	nucleotide binding magnesium ion binding actin binding myosin light chain kinase activity calcium ion binding calmodulin binding ATP binding protein amino acid phosphorylation transferase activity	Calcium signaling pathway Vascular smooth muscle contraction Focal adhesion Regulation of actin cytoskeleton
209004_s_at	0.362	10.040	3.227	5.554e-03	0.130	-2.182	FBXL5	F-box and leucine-rich repeat protein 5	4	-15215251	AF142481	26234	4p15.32	Hs.643433	13	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process
214764_at	-0.700	6.634	-3.227	5.558e-03	0.130	-2.182	RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	1	216525251	AW029169	51018	1q41	Hs.660109	8	protein binding
205633_s_at	0.993	8.371	3.227	5.558e-03	0.130	-2.182	ALAS1	aminolevulinate, delta-, synthase 1	3	52207155, 52207183	NM_000688	211	3p21.1	Hs.476308	24	5-aminolevulinate synthase activity mitochondrion mitochondrial matrix heme biosynthetic process acyltransferase activity transferase activity, transferring nitrogenous groups pyridoxal phosphate binding tetrapyrrole biosynthetic process	Glycine, serine and threonine metabolism Porphyrin and chlorophyll metabolism Metabolic pathways
226818_at	0.800	4.565	3.227	5.561e-03	0.130	-2.183	MPEG1	macrophage expressed 1	11	-58732558	T64884	219972	11q12.1	Hs.718450	4	membrane integral to membrane
239741_at	-0.829	5.578	-3.227	5.562e-03	0.130	-2.183	LOC283658	hypothetical protein LOC283658	15		AA233912	283658	15q21.1	Hs.87194	1
209455_at	-0.367	7.651	-3.227	5.562e-03	0.130	-2.183	FBXW11	F-box and WD repeat domain containing 11	5	-171221160	BE963245	23291	5q35.1	Hs.484138	14	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding cytoplasm Wnt receptor signaling pathway protein ubiquitination modification-dependent protein catabolic process	Ubiquitin mediated proteolysis Wnt signaling pathway Hedgehog signaling pathway
203543_s_at	-0.969	7.801	-3.227	5.564e-03	0.130	-2.183	KLF9	Kruppel-like factor 9	9	-72189332	NM_001206	687	9q13	Hs.150557 Hs.602267	19	transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter embryo implantation zinc ion binding regulation of transcription metal ion binding progesterone receptor signaling pathway
228035_at	0.333	5.211	3.226	5.571e-03	0.130	-2.185	STK33	serine/threonine kinase 33	11	-8369993	AA453640	65975	11p15.3	Hs.501833	8	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm Golgi apparatus protein amino acid phosphorylation transferase activity perinuclear region of cytoplasm
1561206_at	-0.398	3.991	-3.226	5.573e-03	0.130	-2.185	KLHL8	kelch-like 8 (Drosophila)	4	-88301237	BC041370	57563	4q22.1	Hs.106601 Hs.715202	9	protein binding
202207_at	1.144	4.276	3.226	5.574e-03	0.130	-2.185	ARL4C	ADP-ribosylation factor-like 4C	2	-235066424	BG435404	10123	2q37.1	Hs.111554 Hs.719190	7	nucleotide binding GTPase activity GTP binding intracellular nucleus small GTPase mediated signal transduction
224758_at	-0.340	4.495	-3.225	5.577e-03	0.130	-2.185	PL-5283	PL-5283 protein	7	134997760	BG393032	647087	7q33	Hs.200022	3
235164_at	-0.456	6.484	-3.225	5.581e-03	0.130	-2.186	ZNF25	zinc finger protein 25	10	-38278800	BG433539	219749	10p11.1	Hs.499429	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209363_s_at	-0.621	6.747	-3.225	5.582e-03	0.130	-2.186	MED21	mediator complex subunit 21	12	27066749	U46837	9412	12p11.23	Hs.286145	27	blastocyst development RNA polymerase II transcription factor activity transcription coactivator activity DNA-directed RNA polymerase activity protein binding nucleus DNA-directed RNA polymerase II, core complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter
224992_s_at	0.298	4.934	3.224	5.589e-03	0.130	-2.187	CMIP	c-Maf-inducing protein	16	80036275, 80086454	AI363061	80790	16q23	Hs.709248	7	nucleus cytoplasm
200904_at	0.480	7.547	3.224	5.599e-03	0.130	-2.189	HLA-E	major histocompatibility complex, class I, E	6	30565249, 1905841, 1704132	X56841	3133	6p21.3	Hs.650174	126	antigen processing and presentation of peptide antigen via MHC class I plasma membrane immune response integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
227143_s_at	0.361	6.100	3.223	5.603e-03	0.130	-2.190	BID	BH3 interacting domain death agonist	22	-16596905, -16596905	AA706658	637	22q11.1	Hs.591054	111	release of cytochrome c from mitochondria death receptor binding protein binding membrane fraction cytoplasm mitochondrion mitochondrial outer membrane cytosol cytosol induction of apoptosis via death domain receptors activation of pro-apoptotic gene products membrane regulation of mitochondrial membrane permeability neuron apoptosis	p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer
223071_at	-0.381	9.514	-3.223	5.604e-03	0.130	-2.190	IER3IP1	immediate early response 3 interacting protein 1	18	-42935410	AL136667	51124	18q12	Hs.653122	9	endoplasmic reticulum Golgi apparatus membrane integral to membrane
203487_s_at	-0.458	8.120	-3.222	5.613e-03	0.130	-2.192	ARMC8	armadillo repeat containing 8	3	139388837, 139388837	NM_015396	25852	3q22.3	Hs.719108	4	binding
236640_at	0.487	4.774	3.222	5.620e-03	0.130	-2.193	LOC399959	hypothetical LOC399959	11	-121465022	AI638169	399959	11q24.1	Hs.44098	2
1555886_at	0.483	6.268	3.222	5.620e-03	0.130	-2.193	PDSS2	prenyl (decaprenyl) diphosphate synthase, subunit 2	6	-107580453	BC029491	57107	6q21	Hs.718509	9	trans-hexaprenyltranstransferase activity ubiquinone biosynthetic process isoprenoid biosynthetic process transferase activity protein heterodimerization activity	Terpenoid backbone biosynthesis
203359_s_at	-0.551	6.336	-3.221	5.622e-03	0.130	-2.193	MYCBP	c-myc binding protein	1	-39101222	AL525412	26292	1p33-p32.2	Hs.591506	12	transcription coactivator activity protein binding nucleus cytoplasm mitochondrion spermatogenesis regulation of transcription
226596_x_at	-0.887	6.794	-3.221	5.628e-03	0.130	-2.194	tcag7.903	hypothetical protein LOC729852	7		AK027125	729852	7p21.3	Hs.652371	1
201599_at	-0.734	9.166	-3.220	5.641e-03	0.130	-2.196	OAT	ornithine aminotransferase (gyrate atrophy)	10	-126075861	NM_000274	4942	10q26	Hs.523332	28	ornithine-oxo-acid transaminase activity protein binding cytoplasm mitochondrion mitochondrial matrix visual perception transferase activity pyridoxal phosphate binding	Arginine and proline metabolism Metabolic pathways
219622_at	0.737	5.704	3.219	5.652e-03	0.131	-2.198	RAB20	RAB20, member RAS oncogene family	13	-109973413	NM_017817	55647	13q34	Hs.719403	7	nucleotide binding GTP binding Golgi apparatus small GTPase mediated signal transduction protein transport
232458_at	0.552	5.150	3.219	5.655e-03	0.131	-2.198	COL3A1	collagen, type III, alpha 1	2	189547343	AU146808	1281	2q31	Hs.443625 Hs.708235	130	integrin binding integrin binding extracellular matrix structural constituent protein binding extracellular region collagen collagen type III collagen type III extracellular space extracellular space cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway heart development response to radiation peptide cross-linking platelet activation collagen fibril organization collagen fibril organization collagen biosynthetic process collagen biosynthetic process response to cytokine stimulus wound healing wound healing fibril organization skin development platelet-derived growth factor binding negative regulation of immune response	Focal adhesion ECM-receptor interaction
203369_x_at	-0.439	7.046	-3.219	5.655e-03	0.131	-2.198	PDLIM7	PDZ and LIM domain 7 (enigma)	5	-176849852, -176843000	AI825846	9260	5q35.3	Hs.533040	22	ossification protein binding cytoplasm cytoskeleton receptor-mediated endocytosis multicellular organismal development zinc ion binding cell differentiation metal ion binding
233898_s_at	-0.463	7.734	-3.218	5.668e-03	0.131	-2.201	FGFR1OP2	FGFR1 oncogene partner 2	12	26982582	AL117545	26127	12p11.23	Hs.591162	5	cytoplasm
223585_x_at	-0.765	5.827	-3.217	5.672e-03	0.131	-2.201	KBTBD2	kelch repeat and BTB (POZ) domain containing 2	7	-32874302	AF151831	25948	7p14.3	Hs.372541	4	protein binding
228149_at	-0.503	5.522	-3.217	5.672e-03	0.131	-2.201	C7orf60	chromosome 7 open reading frame 60	7	-112246437	BF432926	154743	7q31.1	Hs.489734	4
224518_s_at	0.575	4.385	3.217	5.672e-03	0.131	-2.201	ZNF559	zinc finger protein 559	19	9295927	BC006436	84527	19p13.2	Hs.655107	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552789_at	-0.444	4.295	-3.217	5.675e-03	0.131	-2.202	SEC62	SEC62 homolog (S. cerevisiae)	3	171167273	NM_153039	7095	3q26.2	Hs.622596	10	receptor activity endoplasmic reticulum cytoskeleton cotranslational protein targeting to membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport
219419_at	-0.399	6.838	-3.216	5.691e-03	0.131	-2.204	C18orf22	chromosome 18 open reading frame 22	18	75895345	NM_024805	79863	18q23	Hs.593610	3	mitochondrion rRNA processing
1565765_x_at	0.232	3.379	3.214	5.706e-03	0.131	-2.207	C13orf33	chromosome 13 open reading frame 33	13	30378311	AL832478	84935	13q12.3	Hs.646647 Hs.708377	4
213523_at	0.303	5.997	3.214	5.713e-03	0.131	-2.208	CCNE1	cyclin E1	19	34994740, 34995400	AI671049	898	19q12	Hs.244723	144	G1/S transition of mitotic cell cycle transcription coactivator activity protein binding nucleus nucleoplasm cytosol cell cycle androgen receptor signaling pathway positive regulation of transcription, DNA-dependent androgen receptor binding cell division	Cell cycle p53 signaling pathway Pathways in cancer Prostate cancer Small cell lung cancer
229794_at	0.560	4.663	3.213	5.725e-03	0.132	-2.210	ZNF585A	zinc finger protein 585A	19	-42332840, -42332840	BE550717	199704	19q13.12	Hs.390568 Hs.659236	3	nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211069_s_at	-0.218	9.470	-3.212	5.729e-03	0.132	-2.210	SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	2	-202779147	BC006462	7341	2q33	Hs.596171 Hs.81424	228	protein binding nucleus nuclear pore cytoplasm DNA repair membrane negative regulation of transcription negative regulation of transcription PML body nuclear speck protein sumoylation modification-dependent protein catabolic process positive regulation of protein complex assembly nuclear membrane regulation of protein localization negative regulation of transcription factor activity
225396_at	-0.553	5.767	-3.212	5.733e-03	0.132	-2.211	RBBP4	retinoblastoma binding protein 4	1	32889335, 32889545	AI928212	5928	1p35.1	Hs.16003	70	nucleus DNA replication chromatin remodeling cell cycle DNA-dependent ATPase activity negative regulation of cell proliferation Sin3 complex NuRD complex histone binding histone deacetylase binding regulation of transcription
222479_s_at	-0.366	8.021	-3.212	5.737e-03	0.132	-2.212	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	3	-32542470	AK001081	51143	3p22.3	Hs.529495	11	nucleotide binding motor activity ATP binding microtubule dynein complex
211763_s_at	-0.716	9.793	-3.211	5.740e-03	0.132	-2.212	UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	5	133734768	BC005979	7320	5q23-q31	Hs.615284 Hs.644421	23	nucleotide binding protein polyubiquitination chromatin ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus replication fork cytoplasm plasma membrane postreplication repair postreplication repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein monoubiquitination response to DNA damage stimulus spermatogenesis sperm axoneme assembly response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination response to drug protein stabilization regulation of protein metabolic process protein autoubiquitination Wnt receptor signaling pathway through beta-catenin	Ubiquitin mediated proteolysis
211833_s_at	0.364	3.869	3.211	5.740e-03	0.132	-2.212	BAX	BCL2-associated X protein	19	54149928, 54149928, 54149928	U19599	581	19q13.3-q13.4	Hs.624291	448	B cell apoptosis B cell apoptosis release of cytochrome c from mitochondria cytoplasm mitochondrion mitochondrial outer membrane mitochondrial permeability transition pore complex endoplasmic reticulum endoplasmic reticulum membrane cytosol cytosol DNA fragmentation involved in apoptosis cleavage of lamin transformed cell apoptosis mitochondrial fusion lipid binding induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals negative regulation of survival gene product expression activation of caspase activity by cytochrome c response to toxin establishment or maintenance of transmembrane electrochemical gradient membrane integral to membrane nuclear fragmentation during apoptosis release of matrix enzymes from mitochondria protein homodimerization activity protein homodimerization activity regulation of apoptosis regulation of protein homodimerization activity regulation of protein heterodimerization activity positive regulation of neuron apoptosis mitochondrial fragmentation during apoptosis induction of retinal programmed cell death protein heterodimerization activity protein homooligomerization BH3 domain binding regulation of mitochondrial membrane potential	p53 signaling pathway Apoptosis Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Huntington's disease Prion diseases Pathways in cancer Colorectal cancer
212423_at	-0.526	8.252	-3.210	5.752e-03	0.132	-2.214	ZCCHC24	zinc finger, CCHC domain containing 24	10	-80812090	AK024784	219654	10q22.3	Hs.523080	5	nucleic acid binding zinc ion binding metal ion binding
230276_at	-0.390	4.747	-3.210	5.753e-03	0.132	-2.214	FAM49A	family with sequence similarity 49, member A	2	-16597381	AI934342	81553	2p24.2	Hs.467769	8	intracellular
203244_at	-0.354	8.432	-3.210	5.757e-03	0.132	-2.215	PEX5	peroxisomal biogenesis factor 5	12	7233025, 7233548, 7234224	NM_000319	5830	12p13.31	Hs.567327	45	protein binding cytoplasm peroxisome protein transport membrane
213002_at	0.544	5.961	3.210	5.758e-03	0.132	-2.215	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	AA770596	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
219081_at	-0.773	6.824	-3.210	5.761e-03	0.132	-2.215	ANKHD1	ankyrin repeat and KH domain containing 1	5	139761612, 139761612	NM_024668	54882	5q31.3	Hs.594084	12	RNA binding protein binding cytoplasm
224877_s_at	0.371	7.952	3.209	5.767e-03	0.132	-2.216	MRPS5	mitochondrial ribosomal protein S5	2	-95116678	BE970056	64969	2p11.2-q11.2	Hs.655259	9	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion ribosome translation
213864_s_at	-0.455	9.661	-3.209	5.769e-03	0.132	-2.217	NAP1L1	nucleosome assembly protein 1-like 1	12	-74724938	AI985751	4673	12q21.2	Hs.524599 Hs.695185	17	protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome
228785_at	-0.412	7.557	-3.209	5.770e-03	0.132	-2.217	ZNF281	zinc finger protein 281	1	-198642042	AA121673	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
229422_at	-0.631	6.298	-3.209	5.771e-03	0.132	-2.217	NRD1	nardilysin (N-arginine dibasic convertase)	1	-52027453	AA448346	4898	1p32.2-p32.1	Hs.584782	18	metalloendopeptidase activity protein binding cytosol proteolysis neuromuscular junction development peptidase activity zinc ion binding cell proliferation cell surface cell migration metal ion binding epidermal growth factor binding positive regulation of membrane protein ectodomain proteolysis regulation of endopeptidase activity
202863_at	0.487	6.380	3.209	5.773e-03	0.132	-2.217	SP100	SP100 nuclear antigen	2	230989114, 230989114	NM_003113	6672	2q37.1	Hs.369056	34	negative regulation of transcription from RNA polymerase II promoter DNA binding transcription coactivator activity transcription corepressor activity nucleus chromosome DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator PML body kinase binding protein domain specific binding response to type I interferon response to type I interferon response to interferon-gamma response to interferon-gamma protein homodimerization activity negative regulation of transcription factor activity interspecies interaction between organisms positive regulation of transcription, DNA-dependent negative regulation of cell motion interferon-gamma-mediated signaling pathway type I interferon-mediated signaling pathway
231927_at	-0.518	5.488	-3.208	5.779e-03	0.132	-2.218	ATF6	activating transcription factor 6	1	160002707	BF671883	22926	1q22-q23	Hs.492740	43	transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity nucleus nuclear envelope nucleoplasm endoplasmic reticulum endoplasmic reticulum membrane regulation of transcription from RNA polymerase II promoter protein folding response to unfolded protein positive regulation of gene-specific transcription involved in unfolded protein response signal transduction membrane integral to membrane sequence-specific DNA binding protein dimerization activity	Alzheimer's disease
211938_at	-0.292	10.524	-3.208	5.780e-03	0.132	-2.218	EIF4B	eukaryotic translation initiation factor 4B	12	51686328	BF247371	1975	12q13.13	Hs.648394 Hs.702041	23	nucleotide binding RNA binding translation initiation factor activity cytosol translation regulation of translational initiation eukaryotic translation initiation factor 4F complex	mTOR signaling pathway
1554127_s_at	-0.657	8.134	-3.208	5.782e-03	0.132	-2.219	MSRB3	methionine sulfoxide reductase B3	12	63958754	BC040053	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
204447_at	0.328	6.198	3.207	5.790e-03	0.132	-2.220	ProSAPiP1	ProSAPiP1 protein	20	-3091272	NM_014731	9762	20p13	Hs.90232	4	structural molecule activity cytoplasm membrane
1560562_a_at	0.533	4.040	3.207	5.793e-03	0.132	-2.221	ZNF677	zinc finger protein 677	19	-58430449	AK026366	342926	19q13.42	Hs.20506	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218761_at	-0.419	7.007	-3.206	5.800e-03	0.132	-2.222	RNF111	ring finger protein 111	15	57067156	NM_017610	54778	15q21	Hs.404423	13	protein binding nucleus cytoplasm multicellular organismal development zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
215691_x_at	0.452	7.146	3.206	5.802e-03	0.132	-2.222	HSPB11	heat shock protein family B (small), member 11	1	-54159821	AV702994	51668	1p32.1-p33	Hs.525462 Hs.624686	9	response to stress cell adhesion
205984_at	0.457	3.481	3.206	5.807e-03	0.132	-2.223	CRHBP	corticotropin releasing hormone binding protein	5	76284435	NM_001882	1393	5q11.2-q13.3	Hs.115617	31	protein binding extracellular space soluble fraction signal transduction female pregnancy learning or memory adrenocorticotropin-releasing hormone binding hormone metabolic process
202464_s_at	-1.838	8.632	-3.204	5.824e-03	0.132	-2.225	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	10	6226848, 6284845	NM_004566	5209	10p14-p15	Hs.719094	28	nucleotide binding 6-phosphofructo-2-kinase activity 6-phosphofructo-2-kinase activity fructose-2,6-bisphosphate 2-phosphatase activity ATP binding cellular_component cytosol fructose 2,6-bisphosphate metabolic process metabolic process kinase activity transferase activity hydrolase activity identical protein binding	Fructose and mannose metabolism
236728_at	0.785	4.987	3.204	5.824e-03	0.132	-2.225	LNPEP	leucyl/cystinyl aminopeptidase	5	96297101, 96319911	AW070437	4012	5q15	Hs.527199 Hs.656905	44	aminopeptidase activity extracellular region intracellular plasma membrane integral to plasma membrane proteolysis cell-cell signaling female pregnancy peptidase activity metallopeptidase activity zinc ion binding metal ion binding	Renin-angiotensin system
215368_at	-0.569	8.289	-3.204	5.829e-03	0.132	-2.226	NEB	nebulin	2	-152050098	R78299	4703	2q22	Hs.588655	32	actin binding protein binding cytoplasm somatic muscle development structural constituent of muscle actin cytoskeleton sarcomere Z disc regulation of actin filament length
1557132_at	0.230	2.251	3.203	5.841e-03	0.132	-2.228	WDR17	WD repeat domain 17	4	177224125	BI713506	116966	4q34	Hs.532056	3
226519_s_at	0.496	6.955	3.202	5.848e-03	0.133	-2.229	AGXT2L2	alanine-glyoxylate aminotransferase 2-like 2	5	-177568146	AL561859	85007	5q35.3	Hs.248746	4	mitochondrion transaminase activity transferase activity pyridoxal phosphate binding
229855_at	-0.831	5.085	-3.202	5.855e-03	0.133	-2.230	RNF34	ring finger protein 34	12	120322284	AA779208	80196	12q24.31	Hs.292804	11	protein binding nucleus apoptosis zinc ion binding membrane nuclear speck ligase activity modification-dependent protein catabolic process metal ion binding
212718_at	-0.347	8.732	-3.202	5.858e-03	0.133	-2.231	PAPOLA	poly(A) polymerase alpha	14	96038472	BF797555	10914	14q32.31	Hs.719187	17	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding polynucleotide adenylyltransferase activity ATP binding nucleus nucleolus cytoplasm transcription mRNA polyadenylation transferase activity nucleotidyltransferase activity	RNA degradation
219244_s_at	0.563	8.261	3.199	5.888e-03	0.133	-2.236	MRPL46	mitochondrial ribosomal protein L46	15	-86803712	NM_022163	26589	15q24-q25	Hs.534261	6	molecular_function cellular_component mitochondrion ribosome biological_process
1554966_a_at	-0.633	7.394	-3.199	5.892e-03	0.133	-2.236	FILIP1L	filamin A interacting protein 1-like	3	-101049461, -101049461, -101034677	AF329092	11259	3q12.1	Hs.104672	8	molecular_function nucleus cytoplasm biological_process membrane myosin complex
204263_s_at	0.504	6.825	3.198	5.902e-03	0.133	-2.238	CPT2	carnitine palmitoyltransferase 2	1	53434688	M58581	1376	1p32	Hs.713535	53	carnitine O-palmitoyltransferase activity carnitine O-palmitoyltransferase activity mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation transport carnitine shuttle acyltransferase activity membrane transferase activity regulation of fatty acid oxidation	Fatty acid metabolism PPAR signaling pathway
224952_at	0.354	4.534	3.198	5.904e-03	0.133	-2.238	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	17	58440629	BF115054	26115	17q23.2-q23.3	Hs.410889	3	binding
211110_s_at	-0.544	6.035	-3.198	5.904e-03	0.133	-2.238	AR	androgen receptor	X	66680598, 66705407	AF162704	367	Xq11.2-q12	Hs.496240	1010	in utero embryonic development transcription factor activity receptor activity androgen receptor activity androgen receptor activity receptor binding androgen binding nucleus cytoplasm transport signal transduction cell-cell signaling sex differentiation cell death zinc ion binding cell proliferation male gonad development cell growth male somatic sex determination androgen receptor signaling pathway prostate gland development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter metal ion binding protein dimerization activity regulation of catalytic activity	Pathways in cancer Prostate cancer
219421_at	-0.511	7.286	-3.198	5.907e-03	0.133	-2.238	TTC33	tetratricopeptide repeat domain 33	5	-40747434	NM_012382	23548	5p15.2-p12	Hs.348915 Hs.621357	3	binding
200979_at	0.975	7.231	3.197	5.914e-03	0.133	-2.240	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	X	19271931	BF739979	5160	Xp22.2-p22.1	Hs.530331	54	pyruvate dehydrogenase (acetyl-transferring) activity protein binding mitochondrion mitochondrial matrix glycolysis oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
226595_at	0.272	6.249	3.195	5.935e-03	0.134	-2.243	SNX21	sorting nexin family member 21	20	43895876	AI935964	90203	20q13.12	Hs.472854	8	protein binding cell communication protein transport phosphoinositide binding
235030_at	-0.467	6.982	-3.195	5.936e-03	0.134	-2.243	FAM55C	family with sequence similarity 55, member C	3	102980718, 102980975	BF969254	91775	3q12.3	Hs.595933	4	extracellular region
223804_s_at	0.431	7.609	3.195	5.938e-03	0.134	-2.243	THUMPD3	THUMP domain containing 3	3	9379716	BC001622	25917	3p25.3	Hs.443081	5	RNA binding protein binding methyltransferase activity transferase activity
225521_at	-0.501	5.871	-3.195	5.940e-03	0.134	-2.244	ANAPC7	anaphase promoting complex subunit 7	12	-109297656, -109295087	AL137586	51434	12q24.11	Hs.524741	30	binding nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
224607_s_at	-0.301	8.276	-3.194	5.945e-03	0.134	-2.245	SRP68	signal recognition particle 68kDa	17	-71546785	BG398597	6730	17q25.1	Hs.514495	11	RNA binding signal recognition particle binding nucleus nucleolus cytoplasm endoplasmic reticulum signal recognition particle, endoplasmic reticulum targeting ribosome response to drug	Protein export
227877_at	0.381	5.797	3.194	5.952e-03	0.134	-2.246	C5orf39	chromosome 5 open reading frame 39	5	-43074939	AI991103	389289	5p12	Hs.529385	5	receptor activity
1557067_s_at	-0.429	6.063	-3.193	5.956e-03	0.134	-2.246	LUC7L	LUC7-like (S. cerevisiae)	16	-178974, -178970	AI744735	55692	16p13.3	Hs.16803	11	protein binding nucleus zinc ion binding negative regulation of striated muscle development metal ion binding RS domain binding
224871_at	-0.369	7.753	-3.193	5.956e-03	0.134	-2.246	TPRG1L	tumor protein p63 regulated 1-like	1	3531415	AK025464	127262	1p36.32	Hs.20529	5	synaptic vesicle cell junction cytoplasmic vesicle synapse
203932_at	0.430	6.464	3.192	5.970e-03	0.134	-2.248	HLA-DMB	major histocompatibility complex, class II, DM beta	6	-33010392, -4283265, -4088488	NM_002118	3109	6p21.3	Hs.654428	76	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II lysosome endosome plasma membrane immune response integral to membrane MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
203185_at	0.477	4.349	3.192	5.970e-03	0.134	-2.248	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	20	-4708669, -4708668	NM_014737	9770	20pter-p12.1	Hs.631504	20	protein binding nucleus cell cycle signal transduction
205163_at	-0.737	13.398	-3.191	5.981e-03	0.134	-2.250	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	16	30293623	NM_013292	29895	16p11.2	Hs.50889	5	motor activity calcium ion binding muscle myosin complex skeletal muscle tissue development structural constituent of muscle myosin complex	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
207871_s_at	-0.706	5.548	-3.191	5.983e-03	0.134	-2.250	ST7	suppression of tumorigenicity 7	7	116380616, 116380616	NM_018412	7982	7q31.1-q31.3	Hs.368131	21	membrane integral to membrane
214579_at	0.339	4.474	3.190	5.993e-03	0.134	-2.252	NIPAL3	NIPA-like domain containing 3	1	24614831	NM_020448	57185	1p36.12-p35.1	Hs.523442	6	membrane integral to membrane
226902_at	-0.438	10.746	-3.190	6.001e-03	0.134	-2.253	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	3	180853626	BF109140	8975	3q26.2-q26.3	Hs.175322	11	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding
205843_x_at	0.360	8.314	3.189	6.010e-03	0.134	-2.254	CRAT	carnitine acetyltransferase	9	-130896895, -130896893	NM_000755	1384	9q34.1	Hs.12068	10	carnitine O-acetyltransferase activity mitochondrion mitochondrial inner membrane peroxisome endoplasmic reticulum lipid metabolic process fatty acid metabolic process transport acyltransferase activity energy derivation by oxidation of organic compounds membrane transferase activity
204651_at	-0.374	6.531	-3.189	6.010e-03	0.134	-2.255	NRF1	nuclear respiratory factor 1	7	129038790, 129057154	AW003022	4899	7q32	Hs.654363	47	DNA binding nucleus generation of precursor metabolites and energy regulation of transcription from RNA polymerase II promoter regulation of transcription	Huntington's disease
205552_s_at	0.462	4.267	3.189	6.012e-03	0.134	-2.255	OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	12	111829121, 111829121	NM_002534	4938	12q24.1	Hs.524760	44	nucleotide binding RNA binding ATP binding nucleus cytoplasm mitochondrion endoplasmic reticulum microsome nucleobase, nucleoside, nucleotide and nucleic acid metabolic process immune response transferase activity nucleotidyltransferase activity
214909_s_at	0.350	6.284	3.189	6.015e-03	0.134	-2.255	DDAH2	dimethylarginine dimethylaminohydrolase 2	6	-31802795, -3140940, -2942393	AK026191	23564	6p21.3	Hs.247362	22	protein binding cytoplasm cytosol arginine catabolic process nitric oxide biosynthetic process anti-apoptosis defense response response to unfolded protein nitric oxide mediated signal transduction response to nutrient dimethylargininase activity hydrolase activity protein complex NF-kappaB binding
203371_s_at	0.224	11.399	3.189	6.017e-03	0.134	-2.255	NDUFB3	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa	2	201644706	NM_002491	4709	2q31.3	Hs.109760	8	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
201641_at	0.432	6.649	3.188	6.027e-03	0.135	-2.257	BST2	bone marrow stromal cell antigen 2	19	-17374754	NM_004335	684	19p13.2	Hs.118110	20	signal transducer activity Golgi apparatus plasma membrane integral to plasma membrane humoral immune response cell-cell signaling multicellular organismal development cell proliferation response to virus anchored to membrane B cell activation positive regulation of I-kappaB kinase/NF-kappaB cascade
219963_at	-0.401	10.097	-3.187	6.036e-03	0.135	-2.258	DUSP13	dual specificity phosphatase 13	10	-76524197, -76524195	NM_016364	51207	10q22.2	Hs.178170	9	protein tyrosine phosphatase activity protein amino acid dephosphorylation meiosis spermatogenesis protein tyrosine/serine/threonine phosphatase activity hydrolase activity
235033_at	-0.416	5.786	-3.185	6.058e-03	0.135	-2.262	NPEPL1	aminopeptidase-like 1	20	56701267	AL577823	79716	20q13.32	Hs.554211 Hs.654868	7	aminopeptidase activity intracellular proteolysis peptidase activity zinc ion binding manganese ion binding metal ion binding
212308_at	-0.737	6.284	-3.184	6.073e-03	0.135	-2.264	CLASP2	cytoplasmic linker associated protein 2	3	-33512741	AL137636	23122	3p22.3	Hs.108614	17	condensed chromosome kinetochore protein binding cytoplasm Golgi apparatus centrosome spindle kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity galactoside 2-alpha-L-fucosyltransferase activity regulation of microtubule polymerization or depolymerization microtubule plus-end binding cell division
218772_x_at	-0.802	8.424	-3.183	6.083e-03	0.136	-2.266	TMEM38B	transmembrane protein 38B	9	107496645	NM_018112	55151	9q31.2	Hs.411925	5	potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
203544_s_at	-0.408	7.175	-3.183	6.086e-03	0.136	-2.266	STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	10	17726129	NM_003473	8027	10p14-p13	Hs.441498	30	SH3/SH2 adaptor activity protein binding cytoplasm endosome cytosol intracellular protein transport signal transduction membrane	Endocytosis Jak-STAT signaling pathway
203299_s_at	-0.428	8.217	-3.182	6.093e-03	0.136	-2.267	AP1S2	adaptor-related protein complex 1, sigma 2 subunit	X	-15753849	AF251295	8905	Xp22.2	Hs.653504 Hs.656471	21	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
206015_s_at	-0.413	8.121	-3.182	6.102e-03	0.136	-2.269	FOXJ3	forkhead box J3	1	-42414796	NM_014947	22887	1pter-q31.3	Hs.26023	4	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
217226_s_at	0.364	5.217	3.181	6.113e-03	0.136	-2.270	SFXN3	sideroflexin 3	10	102780985	M95929	81855	10q24.31	Hs.283844	3	iron ion binding mitochondrion cation transport iron ion transport cation transmembrane transporter activity membrane integral to membrane
228702_at	-0.807	7.814	-3.181	6.117e-03	0.136	-2.271	FLJ43663	hypothetical LOC378805	7	-130279458, -130279458	AL569506	378805	7q32.3	Hs.150556 Hs.649308	2
202198_s_at	0.389	4.696	3.179	6.133e-03	0.136	-2.273	MTMR3	myotubularin related protein 3	22	28609157	AF233438	8897	22q12.2	Hs.474536	16	protein serine/threonine phosphatase activity protein tyrosine phosphatase activity membrane fraction cytoplasm protein amino acid dephosphorylation zinc ion binding membrane hydrolase activity metal ion binding
201764_at	0.391	7.300	3.179	6.137e-03	0.136	-2.274	TMEM106C	transmembrane protein 106C	12	46643596	NM_024056	79022	12q13.1	Hs.596726	5	molecular_function cellular_component endoplasmic reticulum biological_process membrane integral to membrane
204000_at	0.327	5.556	3.179	6.139e-03	0.136	-2.274	GNB5	guanine nucleotide binding protein (G protein), beta 5	15	-50200414, -50200414	NM_016194	10681	15q21.2	Hs.155090	26	GTPase activity signal transducer activity protein binding nucleus heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway	Chemokine signaling pathway
228882_at	0.463	5.286	3.178	6.151e-03	0.136	-2.276	TUB	tubby homolog (mouse)	11	8016755, 8059484	AL042088	7275	11p15.5	Hs.231850 Hs.568986	16	nucleus cytoplasm response to stimulus
208822_s_at	0.327	8.909	3.178	6.154e-03	0.136	-2.276	DAP3	death associated protein 3	1	153925497, 153925497	U18321	7818	1q21-q22	Hs.516746	26	protein binding mitochondrion mitochondrial ribosome ribosome induction of apoptosis by extracellular signals apoptotic mitochondrial changes small ribosomal subunit
236473_at	0.278	3.843	3.178	6.154e-03	0.136	-2.276	CC2D2A	coiled-coil and C2 domain containing 2A	4	15080586, 15080586, 15089933	AI765222	57545	4p15.32	Hs.590928	8	cytoplasm cilium microtubule basal body cell projection organization
227887_at	0.415	5.556	3.178	6.155e-03	0.136	-2.276	LOC400236	hypothetical LOC400236	14		AW138940	400236	14q32.11	Hs.585207	1
222660_s_at	-0.252	3.727	-3.177	6.157e-03	0.136	-2.277	RNF38	ring finger protein 38	9	-36326398, -36326398, -36326398	AL136817	152006	9p13	Hs.333503	12	protein binding zinc ion binding metal ion binding
238647_at	-0.531	5.084	-3.177	6.162e-03	0.136	-2.277	C14orf28	chromosome 14 open reading frame 28	14	44436256	AA496213	122525	14q21.2	Hs.82098	3
244727_at	0.314	3.427	3.177	6.163e-03	0.136	-2.278	KCNQ1OT1	KCNQ1 overlapping transcript 1 (non-protein coding)	11	-2618343	BF592986	10984	11p15	Hs.647285 Hs.655148	25
1555044_a_at	-0.701	8.384	-3.177	6.165e-03	0.136	-2.278	KBTBD5	kelch repeat and BTB (POZ) domain containing 5	3	42702014	AY176040	131377	3p22.1	Hs.350288	3	protein binding
242477_at	0.281	3.398	3.177	6.167e-03	0.136	-2.278	TTC39B	tetratricopeptide repeat domain 39B	9	-15161560	BF056282	158219	9p22.3	Hs.563630	3	binding
243188_at	0.293	3.340	3.176	6.171e-03	0.136	-2.279	ZNF283	zinc finger protein 283	19	49023312	AI753038	284349	19q13.31	Hs.652513	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218683_at	-0.563	7.184	-3.176	6.175e-03	0.136	-2.279	PTBP2	polypyrimidine tract binding protein 2	1	96959762	NM_021190	58155	1p22.1-p21.3	Hs.596061 Hs.718552	25	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
213082_s_at	0.397	4.502	3.176	6.177e-03	0.136	-2.280	SLC35D2	solute carrier family 35, member D2	9	-98122809	AJ005866	11046	9q22.32	Hs.494556	6	nucleotide-sugar transmembrane transporter activity cellular_component Golgi apparatus biological_process carbohydrate transport membrane integral to membrane
211801_x_at	-0.534	4.834	-3.176	6.179e-03	0.136	-2.280	MFN1	mitofusin 1	3	180548173	AF329637	55669	3q26.33	Hs.478383	16	nucleotide binding GTPase activity GTP binding cytoplasm mitochondrion mitochondrial outer membrane mitochondrial fusion biological_process membrane integral to membrane hydrolase activity
209540_at	0.553	6.134	3.175	6.188e-03	0.136	-2.281	IGF1	insulin-like growth factor 1 (somatomedin C)	12	-101335583, -101313774, -101313774	AU144912	3479	12q22-q23	Hs.160562	714	skeletal system development osteoblast differentiation insulin receptor binding insulin-like growth factor receptor binding insulin-like growth factor receptor binding hormone activity hormone activity protein binding extracellular region extracellular region extracellular region DNA replication anti-apoptosis cell motion signal transduction Ras protein signal transduction nervous system development muscle organ development growth factor activity positive regulation of cell proliferation glycolate metabolic process organ morphogenesis glial cell differentiation positive regulation of phosphoinositide 3-kinase cascade satellite cell maintenance involved in skeletal muscle regeneration muscle hypertrophy myotube cell development positive regulation of smooth muscle cell migration insulin-like growth factor binding protein complex positive regulation of granule cell precursor proliferation water homeostasis proteoglycan biosynthetic process mammary gland development platelet alpha granule lumen regulation of steroid hormone receptor signaling pathway negative regulation of smooth muscle cell apoptosis regulation of multicellular organism growth positive regulation of tyrosine phosphorylation of Stat5 protein positive regulation of gene-specific transcription positive regulation of insulin-like growth factor receptor signaling pathway myoblast differentiation positive regulation of DNA replication positive regulation of DNA replication positive regulation of glycolysis positive regulation of mitosis positive regulation of transcription from RNA polymerase II promoter positive regulation of Ras protein signal transduction phosphoinositide-mediated signaling positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation branching morphogenesis of a tube chondroitin sulfate proteoglycan biosynthetic process positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation regulation of protein metabolic process myoblast proliferation	p53 signaling pathway mTOR signaling pathway Focal adhesion Long-term depression Pathways in cancer Glioma Prostate cancer Melanoma Hypertrophic cardiomyopathy (HCM)
1553551_s_at	0.238	13.655	3.175	6.189e-03	0.136	-2.282	ND2	MTND2	MT		NM_173709	4536			43	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane oxidoreductase activity electron transport chain ATP synthesis coupled electron transport respiratory chain	Oxidative phosphorylation Metabolic pathways Parkinson's disease
222851_at	-0.457	4.566	-3.173	6.207e-03	0.137	-2.284	ZNF654	zinc finger protein 654	3	88270951	AL120354	55279	3p11.1	Hs.591650 Hs.661116	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
202065_s_at	-0.233	5.816	-3.173	6.210e-03	0.137	-2.285	PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	11	69794470, 69794470	BG033593	8500	11q13.3	Hs.530749	17	signal transducer activity protein binding cytoplasm cell-matrix adhesion signal transduction
1555462_at	0.749	5.199	3.172	6.221e-03	0.137	-2.286	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C	2	182558795	AF494535	151242	2q31.3	Hs.10941	3	phosphoprotein phosphatase inhibitor activity cytoplasm signal transduction
213355_at	-1.206	6.136	-3.172	6.222e-03	0.137	-2.286	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	3	99934261	AI989567	10402	3q12.1	Hs.148716	5	Golgi apparatus amino sugar metabolic process protein amino acid glycosylation glycolipid metabolic process sialyltransferase activity protein lipoylation membrane integral to membrane integral to Golgi membrane	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
221563_at	-0.804	7.047	-3.172	6.226e-03	0.137	-2.287	DUSP10	dual specificity phosphatase 10	1	-219941388, -219941388	N36770	11221	1q41	Hs.497822	15	protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation response to stress JNK cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
217952_x_at	-0.519	7.112	-3.172	6.227e-03	0.137	-2.287	PHF3	PHD finger protein 3	6	64414389	BF430956	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
201005_at	0.746	8.565	3.172	6.227e-03	0.137	-2.287	CD9	CD9 molecule	12	6179815	NM_001769	928	12p13.3	Hs.114286	96	protein binding plasma membrane plasma membrane integral to plasma membrane cell motion cell adhesion fusion of sperm to egg plasma membrane platelet activation paranodal junction assembly platelet alpha granule membrane	Hematopoietic cell lineage
210946_at	-0.372	8.838	-3.172	6.228e-03	0.137	-2.287	PPAP2A	phosphatidic acid phosphatase type 2A	5	-54756439	AF014403	8611	5q11	Hs.696231	20	membrane fraction cytosol plasma membrane integral to plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity negative regulation of cell proliferation germ cell migration hydrolase activity regulation of lipid metabolic process androgen receptor signaling pathway phospholipid dephosphorylation	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
206122_at	0.324	6.436	3.171	6.234e-03	0.137	-2.288	SOX15	SRY (sex determining region Y)-box 15	17	-7432221	NM_006942	6665	17p13	Hs.95582	13	negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm chromatin organization male gonad development cell differentiation skeletal muscle regeneration negative regulation of striated muscle development positive regulation of transcription from RNA polymerase II promoter myoblast development
219283_at	-0.411	6.715	-3.171	6.234e-03	0.137	-2.288	C1GALT1C1	C1GALT1-specific chaperone 1	X	-119643561	NM_014158	29071	Xq24	Hs.643920	13	membrane integral to membrane	O-Glycan biosynthesis Metabolic pathways
228593_at	0.258	6.091	3.171	6.237e-03	0.137	-2.289	MTMR9L	myotubularin related protein 9-like	1	-32469848	AI271425	339483	1p35.1	Hs.471067	3
223021_x_at	-0.578	7.356	-3.170	6.245e-03	0.137	-2.290	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	BF241590	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
205034_at	-0.457	3.451	-3.170	6.246e-03	0.137	-2.290	CCNE2	cyclin E2	8	-95961628	NM_004702	9134	8q22.1	Hs.567387	15	cell cycle checkpoint regulation of cyclin-dependent protein kinase activity protein binding nucleus nucleoplasm cytosol cell cycle cell division	Cell cycle p53 signaling pathway Pathways in cancer Prostate cancer Small cell lung cancer
209362_at	-0.506	7.983	-3.170	6.249e-03	0.137	-2.290	MED21	mediator complex subunit 21	12	27066749	AI688580	9412	12p11.23	Hs.286145	27	blastocyst development RNA polymerase II transcription factor activity transcription coactivator activity DNA-directed RNA polymerase activity protein binding nucleus DNA-directed RNA polymerase II, core complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter
223388_s_at	0.243	3.969	3.170	6.251e-03	0.137	-2.291	ZFYVE1	zinc finger, FYVE domain containing 1	14	-72505911, -72505911	AF251025	53349	14q22-q24	Hs.335106	10	phosphatidylinositol binding phosphatidylinositol-3,4,5-trisphosphate binding endoplasmic reticulum Golgi apparatus Golgi stack zinc ion binding phosphatidylinositol-3,4-bisphosphate binding metal ion binding perinuclear region of cytoplasm
224416_s_at	-0.397	5.640	-3.170	6.252e-03	0.137	-2.291	MED28	mediator complex subunit 28	4	17225370	AF358829	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
223104_at	-0.252	7.874	-3.170	6.253e-03	0.137	-2.291	JAGN1	jagunal homolog 1 (Drosophila)	3	9907270	AF212230	84522	3p25.2	Hs.24054	6	endoplasmic reticulum membrane integral to membrane
205160_at	0.416	6.679	3.170	6.255e-03	0.137	-2.291	PEX11A	peroxisomal biogenesis factor 11 alpha	15	-88027290	AL360141	8800	15q26.1	Hs.31034	9	peroxisome peroxisomal membrane integral to peroxisomal membrane signal transduction membrane integral to membrane peroxisome fission
1553070_a_at	-0.564	7.099	-3.169	6.260e-03	0.137	-2.292	MYOZ3	myozenin 3	5	150020596	NM_133371	91977	5q33.1	Hs.91626	7	protein binding cytoplasm Z disc
200593_s_at	-0.267	7.885	-3.168	6.274e-03	0.137	-2.294	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1	-243080224	BC003621	3192	1q44	Hs.106212	47	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding ATP binding nucleus spliceosomal complex RNA splicing cell surface heterogeneous nuclear ribonucleoprotein complex
218794_s_at	-0.318	5.401	-3.168	6.276e-03	0.137	-2.294	TXNL4B	thioredoxin-like 4B	16	-70676258, -70676258, -70676258	NM_017853	54957	16q22.2	Hs.134406	12	nucleus spliceosomal complex mRNA processing cell cycle mitosis RNA splicing
202963_at	-0.456	6.095	-3.166	6.298e-03	0.138	-2.298	RFX5	regulatory factor X, 5 (influences HLA class II expression)	1	-149579739	AW027312	5993	1q21	Hs.632472	27	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent	Antigen processing and presentation Primary immunodeficiency
203143_s_at	0.242	4.637	3.166	6.302e-03	0.138	-2.298	KIAA0040	KIAA0040	1	-173392745, -173392745	T79953	9674	1q24-q25	Hs.518138	6
220588_at	0.291	3.931	3.165	6.315e-03	0.138	-2.300	BCAS4	breast carcinoma amplified sequence 4	20	48844873	NM_017843	55653	20q13.13	Hs.708239	6	cytoplasm
212750_at	0.492	5.627	3.165	6.315e-03	0.138	-2.300	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AB020630	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
212180_at	-0.512	8.482	-3.164	6.328e-03	0.138	-2.302	CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	22	19601713	AK000311	1399	22q11 22q11.21	Hs.592205	89	blood vessel development protein tyrosine kinase activity SH3/SH2 adaptor activity protein binding intracellular signaling cascade JNK cascade Ras protein signal transduction pattern specification process heart development organ morphogenesis anterior/posterior pattern formation thymus development parathyroid gland development	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Focal adhesion Fc gamma R-mediated phagocytosis Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Pathways in cancer Renal cell carcinoma Chronic myeloid leukemia
213095_x_at	0.294	6.262	3.164	6.332e-03	0.138	-2.303	AIF1	allograft inflammatory factor 1	6	31690972, 31691011, 31691767, 3029118, 3029157, 3029913, 2830581, 2830620, 2831376	AF299327	199	6p21.3	Hs.76364	38	calcium ion binding nucleus response to stress inflammatory response cell cycle arrest negative regulation of cell proliferation
217726_at	-0.352	7.621	-3.163	6.347e-03	0.138	-2.305	COPZ1	coatomer protein complex, subunit zeta 1	12	53005177	NM_016057	22818	12q13.2-q13.3	Hs.505652	14	protein binding cytoplasm Golgi apparatus cytosol intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat COPI vesicle coat cytoplasmic vesicle COPI coating of Golgi vesicle
202272_s_at	-0.321	7.031	-3.162	6.354e-03	0.138	-2.306	FBXO28	F-box protein 28	1	222368413	NM_015176	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
228587_at	0.360	5.930	3.162	6.359e-03	0.138	-2.307	FAM83G	family with sequence similarity 83, member G	17	-18815105	BE504892	644815	17p11.2	Hs.710727	8
241383_at	0.368	4.344	3.161	6.365e-03	0.138	-2.307	ZNF385C	zinc finger protein 385C	17		H05959	201181	17q21.2	Hs.443140	2	nucleic acid binding intracellular nucleus zinc ion binding metal ion binding
226086_at	0.568	4.715	3.161	6.366e-03	0.138	-2.308	SYT13	synaptotagmin XIII	11	-45218428	AB037848	57586	11p12-p11	Hs.436643	12	integral to plasma membrane membrane vesicle-mediated transport transport vesicle
202891_at	0.323	7.566	3.161	6.368e-03	0.138	-2.308	NIT1	nitrilase 1	1	159354514	NM_005600	4817	1q21-q22	Hs.517342	7	nitrilase activity nitrogen compound metabolic process biological_process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
51192_at	0.244	6.729	3.161	6.372e-03	0.138	-2.308	SSH3	slingshot homolog 3 (Drosophila)	11	66827494	AA134926	54961	11q13.2	Hs.29173	11	protein tyrosine phosphatase activity nucleus cytoplasm cytoskeleton protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity	Regulation of actin cytoskeleton
223500_at	0.677	3.602	3.161	6.374e-03	0.138	-2.309	CPLX1	complexin 1	4	-768744	BC002471	10815	4p16.3	Hs.478930	16	cytoplasm cytosol neurotransmitter transport exocytosis synaptic transmission syntaxin binding
221927_s_at	0.354	7.441	3.161	6.374e-03	0.138	-2.309	ABHD11	abhydrolase domain containing 11	7	-72789980, -72789935, -72788362, -72788362	AI923458	83451	7q11.23	Hs.647045	9	molecular_function cellular_component biological_process hydrolase activity
213786_at	-0.541	6.373	-3.160	6.386e-03	0.138	-2.310	TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	7	27746262	AI935415	8887	7p15	Hs.34576	21	intracellular apoptosis anti-apoptosis zinc ion binding identical protein binding
200719_at	-0.501	8.289	-3.159	6.390e-03	0.138	-2.311	SKP1	S-phase kinase-associated protein 1	5	-133519980	BE964043	6500	5q31	Hs.171626 Hs.710433	63	protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
217097_s_at	-0.767	4.527	-3.159	6.391e-03	0.138	-2.311	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	AC004990	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
226656_at	-0.405	8.006	-3.159	6.396e-03	0.138	-2.312	CRTAP	cartilage associated protein	3	33130453	AW024741	10491	3p22.3	Hs.719160	10	extracellular region proteinaceous extracellular matrix
223591_at	-0.426	5.993	-3.158	6.403e-03	0.138	-2.313	RNF135	ring finger protein 135	17	26322081	BC005084	84282	17q11.2	Hs.29874	12	protein binding zinc ion binding metal ion binding
214328_s_at	-0.281	11.601	-3.158	6.404e-03	0.138	-2.313	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	R01140	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
228308_at	0.310	5.363	3.158	6.405e-03	0.138	-2.313	FKBP11	FK506 binding protein 11, 19 kDa	12	-47603175, -47602009, -47602009	AI452444	51303	12q13.12	Hs.655103	5	peptidyl-prolyl cis-trans isomerase activity protein folding membrane integral to membrane isomerase activity
207695_s_at	0.660	4.624	3.158	6.406e-03	0.138	-2.313	IGSF1	immunoglobulin superfamily, member 1	X	-130245822, -130235162	NM_001555	3547	Xq25	Hs.22111	15	receptor activity protein binding extracellular region signal transduction membrane integral to membrane regulation of transcription inhibin beta-A binding inhibin beta-B binding
239038_at	-0.694	4.872	-3.158	6.411e-03	0.138	-2.314	C1orf52	chromosome 1 open reading frame 52	1	-85488226	AW015063	148423	1p22.3	Hs.26226	7
230056_at	-0.393	4.275	-3.158	6.412e-03	0.138	-2.314	BPTF	bromodomain PHD finger transcription factor	17	63252241	AI735696	2186	17q24.3	Hs.444200	22	negative regulation of transcription from RNA polymerase II promoter nucleus cytoplasm chromatin remodeling brain development DNA-dependent ATPase activity transcription factor binding zinc ion binding transcription regulator activity positive regulation of gene-specific transcription sequence-specific DNA binding sequence-specific DNA binding regulation of transcription metal ion binding
212386_at	0.341	9.732	3.157	6.415e-03	0.138	-2.315	TCF4	transcription factor 4	18	-51040559	BF592782	6925	18q21.1	Hs.605153	55	transcription factor activity protein binding nucleus regulation of transcription positive regulation of transcription, DNA-dependent protein heterodimerization activity
223004_s_at	0.341	10.197	3.157	6.415e-03	0.138	-2.315	C3orf1	chromosome 3 open reading frame 1	3	120700057	AF210057	51300	3q13.33	Hs.477287	12	mitochondrion membrane integral to membrane
221221_s_at	0.385	6.145	3.157	6.420e-03	0.138	-2.315	KLHL3	kelch-like 3 (Drosophila)	5	-136981087	NM_017415	26249	5q31	Hs.655084	8	actin binding structural molecule activity protein binding cytoplasm cytoskeleton modification-dependent protein catabolic process
1555819_s_at	0.281	5.026	3.157	6.425e-03	0.138	-2.316	SAMD14	sterile alpha motif domain containing 14	17	-45545033	AY148482	201191	17q21.33	Hs.567769	6
224628_at	-0.298	8.307	-3.156	6.428e-03	0.138	-2.316	ERLEC1	endoplasmic reticulum lectin 1	2	53867571	AF131743	27248	2p16.2	Hs.438336 Hs.713845	10	protein binding endoplasmic reticulum endoplasmic reticulum lumen
213249_at	0.260	5.054	3.156	6.428e-03	0.138	-2.316	FBXL7	F-box and leucine-rich repeat protein 7	5	15553304	AU145127	23194	5p15.1	Hs.433057	10	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding ubiquitin-dependent protein catabolic process
201817_at	-0.560	8.642	-3.156	6.433e-03	0.138	-2.317	UBE3C	ubiquitin protein ligase E3C	7	156624415	NM_014671	9690	7q36.3	Hs.118351	9	protein polyubiquitination ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process protein complex	Ubiquitin mediated proteolysis
213274_s_at	-0.445	6.049	-3.156	6.435e-03	0.138	-2.317	CTSB	cathepsin B	8	-11737442	AA020826	1508	8p22	Hs.520898	140	cysteine-type endopeptidase activity extracellular region intracellular soluble fraction mitochondrion lysosome proteolysis peptidase activity response to wounding external side of plasma membrane apical plasma membrane kininogen binding peptide binding melanosome regulation of apoptosis regulation of catalytic activity	Lysosome Antigen processing and presentation
216033_s_at	0.371	4.687	3.156	6.436e-03	0.138	-2.318	FYN	FYN oncogene related to SRC, FGR, YES	6	-112089177, -112089177, -112089177	S74774	2534	6q21	Hs.390567	326	nucleotide binding glycoprotein binding non-membrane spanning protein tyrosine kinase activity ATP binding endosome cytosol plasma membrane protein amino acid phosphorylation calcium ion transport protein kinase cascade multicellular organismal development learning feeding behavior transferase activity manganese ion binding identical protein binding interspecies interaction between organisms metal ion binding T cell receptor signaling pathway	Axon guidance Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway Prion diseases Pathogenic Escherichia coli infection - EHEC
204140_at	0.419	5.469	3.155	6.441e-03	0.139	-2.318	TPST1	tyrosylprotein sulfotransferase 1	7	65307693	NM_003596	8460	7q11.21	Hs.421194	17	membrane fraction Golgi apparatus peptidyl-tyrosine sulfation inflammatory response protein-tyrosine sulfotransferase activity membrane integral to membrane transferase activity
235916_at	0.290	4.205	3.155	6.443e-03	0.139	-2.319	YPEL4	yippee-like 4 (Drosophila)	11	-57169135	BE673815	219539	11q12.1	Hs.135978	4	nucleus nucleolus
203029_s_at	0.286	4.684	3.155	6.449e-03	0.139	-2.319	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2	7	-157024510	NM_002847	5799	7q36	Hs.490789 Hs.715864 Hs.716042	19	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation membrane hydrolase activity	Type I diabetes mellitus
227277_at	-0.471	5.409	-3.154	6.458e-03	0.139	-2.321	MTDH	metadherin	8	98725582	BG530089	92140	8q22.1	Hs.377155	23	negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity
226132_s_at	-0.351	4.695	-3.153	6.478e-03	0.139	-2.324	MANEAL	mannosidase, endo-alpha-like	1	38032360, 38033746	AW272422	149175	1p34.3	Hs.534562 Hs.713176	4	Golgi apparatus membrane integral to membrane hydrolase activity
222090_at	0.272	5.071	3.153	6.479e-03	0.139	-2.324	LOC100134713	hypothetical protein LOC100134713	7	-140041604	BF509069	100134713	7q34	Hs.643181
202803_s_at	0.401	5.036	3.152	6.482e-03	0.139	-2.324	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	21	-45130296, -45130296	NM_000211	3689	21q22.3	Hs.375957	243	glycoprotein binding receptor activity cytoplasm plasma membrane plasma membrane apoptosis inflammatory response cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway cell-cell signaling integrin complex regulation of cell shape integral to membrane protein kinase binding neutrophil chemotaxis regulation of peptidyl-tyrosine phosphorylation	Cell adhesion molecules (CAMs) Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Regulation of actin cytoskeleton
221050_s_at	0.518	7.075	3.151	6.498e-03	0.139	-2.326	GTPBP2	GTP binding protein 2	6	-43696195	NM_019096	54676	6p21-p12	Hs.485449	7	nucleotide binding GTPase activity GTP binding
225277_at	0.249	6.283	3.151	6.504e-03	0.139	-2.327	SLC39A13	solute carrier family 39 (zinc transporter), member 13	11	47386626	AL525780	91252	11p11.2	Hs.523664	3	ion transport zinc ion transport zinc ion binding membrane integral to membrane metal ion transport metal ion transmembrane transporter activity
208136_s_at	0.300	5.683	3.150	6.507e-03	0.139	-2.328	MGC3771	hypothetical LOC81854	16	-3100462	NM_030970	81854	16p13.3	Hs.669490	1
226718_at	-0.407	6.567	-3.150	6.508e-03	0.139	-2.328	AMIGO1	adhesion molecule with Ig-like domain 1	1	-109850968	AA001423	57463	1p13.3	Hs.709892	5	protein binding cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development nervous system development axonal fasciculation membrane integral to membrane cell differentiation axon myelination cell projection positive regulation of axonogenesis
209348_s_at	-0.674	8.347	-3.150	6.509e-03	0.139	-2.328	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	16	-78185246	AF055376	4094	16q22-q23	Hs.134859	37	chromatin cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of chondrocyte differentiation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cell development lens fiber cell differentiation
220778_x_at	0.306	5.295	3.150	6.514e-03	0.139	-2.329	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	19	-4493599	NM_020241	10501	19p13.3	Hs.465642	4	receptor activity multicellular organismal development nervous system development membrane integral to membrane cell differentiation	Axon guidance
208186_s_at	0.373	6.088	3.149	6.525e-03	0.139	-2.330	LIPE	lipase, hormone-sensitive	19	-47597505	NM_005357	3991	19q13.2	Hs.656980	74	triacylglycerol lipase activity protein binding cytoplasm cytosol plasma membrane caveola protein amino acid phosphorylation metabolic process steroid metabolic process cholesterol metabolic process lipid catabolic process hydrolase activity triglyceride catabolic process hormone-sensitive lipase activity diacylglycerol catabolic process	Insulin signaling pathway
214364_at	0.305	6.133	3.149	6.526e-03	0.139	-2.330	MTERFD2	MTERF domain containing 2	2	-241683654, -241675182	W84525	130916	2q37.3	Hs.159556	5
225635_s_at	-0.434	4.809	-3.149	6.530e-03	0.139	-2.331	LOC401504	hypothetical gene supported by AK091718	9		BG535378	401504	9p13.2	Hs.446271	2
209096_at	-0.380	7.394	-3.149	6.533e-03	0.139	-2.331	UBE2V2	ubiquitin-conjugating enzyme E2 variant 2	8	49083547	U62136	7336	8q11.21	Hs.491695	23	protein polyubiquitination DNA double-strand break processing protein binding nucleus cytoplasm regulation of DNA repair cell proliferation small conjugating protein ligase activity modification-dependent protein catabolic process UBC13-MMS2 complex regulation of protein metabolic process
219015_s_at	-0.443	4.438	-3.149	6.534e-03	0.139	-2.331	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)	X	110811068	NM_018466	79868	Xq23	Hs.443061	14	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation	N-Glycan biosynthesis Metabolic pathways
203097_s_at	-0.348	8.111	-3.148	6.544e-03	0.140	-2.333	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	4	160408447	NM_014247	9693	4q32.1	Hs.113912	14	MAPKKK cascade signal transducer activity guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular plasma membrane integral to plasma membrane Rap guanyl-nucleotide exchange factor activity cAMP-mediated signaling diacylglycerol binding Rap GTPase activator activity regulation of small GTPase mediated signal transduction	MAPK signaling pathway
209392_at	0.793	6.341	3.147	6.556e-03	0.140	-2.335	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	8	-120638500, -120638499	L35594	5168	8q24.1	Hs.190977	47	nucleic acid binding phosphodiesterase I activity nucleotide diphosphatase activity extracellular region plasma membrane integral to plasma membrane phosphate metabolic process cell motion chemotaxis G-protein coupled receptor protein signaling pathway transcription factor binding metabolic process lipid catabolic process hydrolase activity metal ion binding alkylglycerophosphoethanolamine phosphodiesterase activity	Ether lipid metabolism
214417_s_at	0.270	3.783	3.147	6.560e-03	0.140	-2.335	FETUB	fetuin B	3	187840842	N39010	26998	3q27	Hs.81073	10	molecular_function cysteine-type endopeptidase inhibitor activity extracellular region biological_process
1565823_at	-0.328	3.155	-3.146	6.571e-03	0.140	-2.337	SEPT7	septin 7	7	35807151	BF855173	989	7p14.3-p14.1	Hs.191346 Hs.642540	23	nucleotide binding condensed chromosome kinetochore cytokinesis stress fiber structural molecule activity protein binding GTP binding nucleus cytoplasm spindle cell cycle mitosis septin complex protein heterooligomerization
208876_s_at	0.288	3.422	3.145	6.575e-03	0.140	-2.337	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	3	197951124	AI076186	5062	3q29	Hs.518530	80	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol negative regulation of protein kinase activity apoptosis signal transduction membrane transferase activity regulation of growth identical protein binding interspecies interaction between organisms protein amino acid autophosphorylation perinuclear region of cytoplasm	MAPK signaling pathway ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
219882_at	-0.444	5.188	-3.145	6.576e-03	0.140	-2.337	TTLL7	tubulin tyrosine ligase-like family, member 7	1	-84107644	NM_024686	79739	1p31.1	Hs.445826	7	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process multicellular organismal development nervous system development ligase activity cell differentiation dendrite perikaryon
227187_at	-0.585	7.288	-3.145	6.586e-03	0.140	-2.339	CBLL1	Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1	7	107171514	AI824009	79872	7q22.3-q31.1	Hs.592271	9	protein binding intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
209358_at	-0.389	7.617	-3.145	6.586e-03	0.140	-2.339	TAF11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	6	-34953532	AF118094	6882	6p21.31	Hs.112444	30	DNA binding transcription coactivator activity nucleus nucleoplasm transcription factor TFIID complex transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter general RNA polymerase II transcription factor activity vitamin D receptor binding positive regulation by host of viral transcription regulation of transcription thyroid hormone receptor binding protein N-terminus binding	Basal transcription factors
212997_s_at	-0.386	6.715	-3.144	6.588e-03	0.140	-2.339	TLK2	tousled-like kinase 2	17	57910117	AU151689	11011	17q23	Hs.445078	10	nucleotide binding regulation of chromatin assembly or disassembly protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus protein amino acid phosphorylation response to DNA damage stimulus cell cycle intracellular signaling cascade chromatin modification transferase activity
219938_s_at	-1.278	7.359	-3.144	6.592e-03	0.140	-2.340	PSTPIP2	proline-serine-threonine phosphatase interacting protein 2	18	-41817499	NM_024430	9050	18q12	Hs.567384	9	cytoplasm membrane
218891_at	-0.291	7.142	-3.144	6.594e-03	0.140	-2.340	C10orf76	chromosome 10 open reading frame 76	10	-103595345	NM_024541	79591	10q24.32	Hs.16004	4	membrane integral to membrane
211026_s_at	0.501	8.747	3.143	6.605e-03	0.140	-2.341	MGLL	monoglyceride lipase	3	-128890598, -128890598	BC006230	11343	3q21.3	Hs.277035	15	lysophospholipase activity lipid metabolic process inflammatory response hydrolase activity acylglycerol lipase activity	Glycerolipid metabolism Metabolic pathways
209035_at	0.260	6.401	3.143	6.614e-03	0.140	-2.343	MDK	midkine (neurite growth-promoting factor 2)	11	46359193, 46359794, 46359878	M69148	4192	11p11.2	Hs.82045	69	extracellular region signal transduction multicellular organismal development nervous system development growth factor activity heparin binding cell proliferation response to wounding cell differentiation adrenal gland development
203636_at	0.242	4.195	3.143	6.615e-03	0.140	-2.343	MID1	midline 1 (Opitz/BBB syndrome)	X	-10373595, -10373595, -10373595	BE967532	4281	Xp22	Hs.27695	38	microtubule cytoskeleton organization protein binding intracellular cytoplasm microtubule microtubule associated complex negative regulation of microtubule depolymerization pattern specification process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
208649_s_at	-0.295	8.396	-3.142	6.618e-03	0.140	-2.343	VCP	valosin-containing protein	9	-35046064	AF100752	7415	9p13.3	Hs.529782	97	nucleotide binding ATP binding nucleus nucleus nucleolus cytoplasm endoplasmic reticulum microsome cytosol double-strand break repair transport activation of caspase activity response to DNA damage stimulus lipid binding protein ubiquitination hydrolase activity ATPase activity protein domain specific binding modification-dependent protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol regulation of apoptosis establishment of protein localization
235809_at	-0.360	3.853	-3.142	6.621e-03	0.140	-2.344	LIN54	lin-54 homolog (C. elegans)	4	-84064780, -84064780	BF678497	132660	4q21.22	Hs.96952	2	nucleus chromosome regulation of transcription
229176_at	-0.426	5.700	-3.142	6.625e-03	0.140	-2.344	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	AI672354	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
201278_at	0.687	6.636	3.142	6.628e-03	0.140	-2.345	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	5	-39407536	N21202	1601	5p13	Hs.481980	47	coated pit protein C-terminus binding cell proliferation membrane clathrin coated vesicle membrane cytoplasmic vesicle	Endocytosis
1559459_at	0.336	3.290	3.141	6.640e-03	0.140	-2.346	LOC613266	hypothetical LOC613266	20		BC043571	613266	20p12.1	Hs.309149	1
201791_s_at	0.274	5.806	3.140	6.644e-03	0.140	-2.347	DHCR7	7-dehydrocholesterol reductase	11	-70823104	NM_001360	1717	11q13.2-q13.5	Hs.503134	48	blood vessel development protein binding nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane cholesterol biosynthetic process post-embryonic development membrane integral to membrane oxidoreductase activity cell differentiation lung development multicellular organism growth regulation of cell proliferation 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity oxidation reduction	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
215247_at	0.263	4.405	3.140	6.645e-03	0.140	-2.347	LOC440895	LIM and senescent cell antigen-like domains 3-like	2	110062555	AI561253	440895	2q13	Hs.372946 Hs.535619	2
232588_at	0.339	4.360	3.140	6.652e-03	0.140	-2.348	STAG1	stromal antigen 1	3	-137538688	AI038943	10274	3q22.3	Hs.412586	11	chromatin protein binding nucleus cell cycle chromosome segregation mitosis cell division	Cell cycle
213050_at	-0.285	5.189	-3.140	6.652e-03	0.140	-2.348	COBL	cordon-bleu homolog (mouse)	7	-51051402	AA594937	23242	7p12.1	Hs.99141	9
224789_at	-0.424	7.100	-3.139	6.657e-03	0.141	-2.349	DCAF12	DDB1 and CUL4 associated factor 12	9	-34076380	AL555107	25853	9p13.3	Hs.493750 Hs.716472	9	cytoplasm centrosome
200653_s_at	-0.382	10.801	-3.139	6.669e-03	0.141	-2.350	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	M27319	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
204362_at	0.769	6.645	3.138	6.671e-03	0.141	-2.351	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	NM_003930	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
218639_s_at	0.332	6.765	3.138	6.671e-03	0.141	-2.351	ZXDC	ZXD family zinc finger C	3	-127652648, -127639133	NM_025112	79364	3q21.3	Hs.440049 Hs.711046	8	nucleic acid binding transcription factor activity intracellular nucleus zinc ion binding transcription activator activity LRR domain binding identical protein binding positive regulation of transcription metal ion binding C2H2 zinc finger domain binding
205231_s_at	-0.496	8.783	-3.137	6.684e-03	0.141	-2.352	EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	6	-145988132	NM_005670	7957	6q24	Hs.486696	37	protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm endoplasmic reticulum cytosol polysome plasma membrane carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity carbohydrate binding
207542_s_at	0.488	7.919	3.136	6.698e-03	0.141	-2.354	AQP1	aquaporin 1 (Colton blood group)	7	30917992	NM_000385	358	7p14	Hs.76152	100	transporter activity protein binding integral to plasma membrane transport water transport excretion water channel activity carbon dioxide transport ammonium transport membrane basolateral plasma membrane apical plasma membrane ammonia transporter activity
219660_s_at	0.424	3.738	3.136	6.706e-03	0.141	-2.355	ATP8A2	ATPase, aminophospholipid transporter-like, class I, type 8A, member 2	13	24844208	NM_016529	51761	13q12	Hs.444957	4	nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process negative regulation of cell proliferation ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
213573_at	-0.340	6.930	-3.136	6.708e-03	0.141	-2.356	KPNB1	karyopherin (importin) beta 1	17	43082273	AA861608	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
1568618_a_at	-0.591	7.864	-3.136	6.708e-03	0.141	-2.356	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	BC038440	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
201353_s_at	0.333	5.617	3.135	6.715e-03	0.141	-2.357	BAZ2A	bromodomain adjacent to zinc finger domain, 2A	12	-55275646	AI653126	11176	12q24.3-qter	Hs.314263	11	chromatin silencing at rDNA DNA binding RNA binding protein binding nucleus chromatin silencing complex nucleolus nucleolus organizer region DNA methylation chromatin remodeling regulation of transcription, DNA-dependent zinc ion binding histone deacetylation transcription regulator activity rDNA heterochromatin metal ion binding histone acetyl-lysine binding
224291_at	-0.234	5.535	-3.135	6.718e-03	0.141	-2.357	CACNG6	calcium channel, voltage-dependent, gamma subunit 6	19	59187353	AF288386	59285	19q13.4	Hs.631560	5	voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding voltage-gated calcium channel complex ion transport calcium ion transport membrane integral to membrane	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
226632_at	0.262	6.270	3.135	6.720e-03	0.141	-2.357	CYGB	cytoglobin	17	-72035034	AL513673	114757	17q25.3	Hs.95120	28	peroxidase activity oxygen transporter activity cytoplasm transport response to oxidative stress oxygen transport oxygen binding heme binding neuron projection cell soma metal ion binding
222701_s_at	0.367	7.226	3.134	6.738e-03	0.141	-2.360	CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7	8	57286868	AA570393	79145	8q12.1	Hs.436913	9
223922_x_at	0.505	6.395	3.133	6.745e-03	0.142	-2.361	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	11	-59696546, -59695655	AB013104	64231	11q12.1	Hs.523702	5	receptor activity signal transduction membrane integral to membrane
1565784_at	-0.386	3.653	-3.132	6.754e-03	0.142	-2.362	LOC100128262	hypothetical LOC100128262	3		AK094115	100128262	3q29	Hs.605240 Hs.679136	1
227583_at	-0.218	5.526	-3.132	6.761e-03	0.142	-2.363	POP4	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	19	34789009	BE742653	10775	19q12	Hs.412870	13	ribonuclease MRP complex RNA binding ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolus rRNA processing mRNA cleavage tRNA processing hydrolase activity ribonuclease P complex identical protein binding
221602_s_at	0.503	5.142	3.132	6.765e-03	0.142	-2.364	FAIM3	Fas apoptotic inhibitory molecule 3	1	-205143252, -205143252	AF057557	9214	1q32.1	Hs.58831 Hs.719320	10	nucleus cytoplasm plasma membrane focal adhesion anti-apoptosis immune response cellular defense response integral to membrane
1557675_at	-0.350	6.739	-3.131	6.771e-03	0.142	-2.364	RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	3	-12600099	BI496583	5894	3p25	Hs.159130	273	nucleotide binding protein serine/threonine kinase activity receptor signaling protein activity protein binding ATP binding mitochondrial outer membrane cytosol plasma membrane protein amino acid phosphorylation apoptosis cytoskeleton organization Ras protein signal transduction zinc ion binding cell proliferation transferase activity diacylglycerol binding metal ion binding nerve growth factor receptor signaling pathway	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Focal adhesion Gap junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
201381_x_at	-0.251	9.087	-3.131	6.775e-03	0.142	-2.365	CACYBP	calcyclin binding protein	1	173235193, 173235514	AF057356	27101	1q24-q25	Hs.508524	15	protein binding nucleus cytoplasm modification-dependent protein catabolic process	Wnt signaling pathway
234937_x_at	0.368	4.384	3.131	6.776e-03	0.142	-2.365	ZFP28	zinc finger protein 28 homolog (mouse)	19	61742128	AC007228	140612		Hs.14794	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225820_at	-0.461	6.981	-3.130	6.787e-03	0.142	-2.367	PHF17	PHD finger protein 17	4	129950228, 129950228	AV646599	79960	4q26-q27	Hs.12420	14	histone acetyltransferase complex protein binding nucleus cytoplasm apoptosis response to stress zinc ion binding negative regulation of cell growth histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation regulation of transcription metal ion binding
218659_at	-0.390	6.876	-3.130	6.790e-03	0.142	-2.367	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	NM_018263	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
225267_at	-0.588	9.492	-3.129	6.794e-03	0.142	-2.367	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	AI935246	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
208209_s_at	0.302	4.459	3.129	6.796e-03	0.142	-2.368	C4BPB	complement component 4 binding protein, beta	1	205328834, 205329206, 205329250	NM_000716	725	1q32	Hs.99886	23	extracellular region complement activation, classical pathway blood coagulation innate immune response	Complement and coagulation cascades
226131_s_at	-0.327	13.104	-3.129	6.797e-03	0.142	-2.368	RPS16	ribosomal protein S16	19	-44615686	AA583817	6217	19q13.1	Hs.397609	24	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
201149_s_at	0.768	8.493	3.129	6.801e-03	0.142	-2.368	TIMP3	TIMP metallopeptidase inhibitor 3	22	31526801	U67195	7078	22q12.1-q13.2 22q12.3	Hs.644633 Hs.714168	117	enzyme inhibitor activity protein binding extracellular region basement membrane visual perception metalloendopeptidase inhibitor activity response to organic cyclic substance tissue regeneration response to estrogen stimulus response to stimulus negative regulation of membrane protein ectodomain proteolysis
220975_s_at	0.229	6.295	3.127	6.829e-03	0.142	-2.372	C1QTNF1	C1q and tumor necrosis factor related protein 1	17	74531845, 74542066	NM_030968	114897	17q25.3	Hs.201398	11	extracellular region
223243_s_at	-0.500	7.242	-3.127	6.835e-03	0.142	-2.373	EDEM3	ER degradation enhancer, mannosidase alpha-like 3	1	-182926247	BF439488	80267	1q24-q25	Hs.523811	10	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen response to unfolded protein membrane
205715_at	0.396	3.667	3.126	6.840e-03	0.142	-2.374	BST1	bone marrow stromal cell antigen 1	4	15313670	NM_004334	683	4p15	Hs.399980	19	NAD+ nucleosidase activity binding plasma membrane humoral immune response multicellular organismal development metabolic process hydrolase activity extrinsic to membrane anchored to membrane	Nicotinate and nicotinamide metabolism Metabolic pathways Calcium signaling pathway
205590_at	0.347	2.619	3.126	6.845e-03	0.142	-2.374	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	15	-36567593	NM_005739	10125	15q14	Hs.591127	21	guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular membrane fraction cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane Ras protein signal transduction zinc ion binding diacylglycerol binding cell differentiation regulation of small GTPase mediated signal transduction	MAPK signaling pathway T cell receptor signaling pathway
230136_at	0.668	5.281	3.125	6.860e-03	0.143	-2.376	LOC400099	hypothetical LOC400099	13		AI573252	400099	13q12.11	Hs.400432
200785_s_at	0.300	6.244	3.125	6.860e-03	0.143	-2.376	LRP1	low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)	12	55808548	NM_002332	4035	12q13-q14	Hs.162757	195	receptor activity lipid transporter activity calcium ion binding membrane fraction nucleus cytoplasm plasma membrane integral to plasma membrane coated pit lipid metabolic process endocytosis multicellular organismal development lipoprotein binding cell proliferation apolipoprotein binding lipoprotein receptor binding	Alzheimer's disease
226895_at	-0.456	10.055	-3.124	6.866e-03	0.143	-2.377	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	19	3310615, 3317572	AW134798	4782	19p13.3	Hs.170131	23	negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus DNA replication regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter
222151_s_at	-0.407	6.749	-3.124	6.873e-03	0.143	-2.378	CEP63	centrosomal protein 63kDa	3	135687264, 135687264, 135687586, 135687736	AK023738	80254	3q22.2	Hs.443301	11	DNA damage checkpoint spindle pole protein binding centrosome spindle assembly
223572_at	-0.441	10.499	-3.124	6.874e-03	0.143	-2.378	HHATL	hedgehog acyltransferase-like	3	-42709159, -42709159	AB042554	57467	3p22.1	Hs.476041	4	protein binding endoplasmic reticulum membrane integral to membrane negative regulation of N-terminal protein palmitoylation
228425_at	0.619	4.928	3.124	6.876e-03	0.143	-2.378	LOC654433	hypothetical LOC654433	2	113710316	BF056746	654433	2q13	Hs.656660	4
226567_at	-0.424	8.468	-3.123	6.879e-03	0.143	-2.379	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	18	148482	BG283995	9097	18p11.32	Hs.464416 Hs.707058	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity
225470_at	-0.511	7.256	-3.123	6.891e-03	0.143	-2.381	NUP35	nucleoporin 35kDa	2	183697327	AL529634	129401	2q32.1	Hs.180591	9	nucleus nuclear pore protein transport mRNA transport intracellular protein transmembrane transport
205037_at	0.327	6.350	3.121	6.915e-03	0.143	-2.384	RABL4	RAB, member of RAS oncogene family-like 4	22	-35484200	NM_006860	11020	22q13.1	Hs.415172	6	nucleotide binding GTP binding small GTPase mediated signal transduction
225106_s_at	-0.494	7.059	-3.121	6.920e-03	0.143	-2.384	OGFOD1	2-oxoglutarate and iron-dependent oxygenase domain containing 1	16	55042924	AK022130	55239	16q12.2	Hs.231883	4	iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors L-ascorbic acid binding metal ion binding oxidation reduction
203669_s_at	-0.416	6.480	-3.121	6.921e-03	0.143	-2.384	DGAT1	diacylglycerol O-acyltransferase homolog 1 (mouse)	8	-145509054, 408762	NM_012079	8694	8q24.3	Hs.571397 Hs.613075	22	diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity endoplasmic reticulum cytosol acyltransferase activity membrane integral to membrane transferase activity triglyceride biosynthetic process very-low-density lipoprotein particle assembly	Glycerolipid metabolism Retinol metabolism Metabolic pathways
227497_at	-0.799	7.132	-3.120	6.928e-03	0.143	-2.385	SOX6	SRY (sex determining region Y)-box 6	11	-15944571, -15944571, -15944571	BE326808	55553	11p15.3	Hs.368226	24	transcription factor activity nucleus chromatin organization regulation of transcription, DNA-dependent multicellular organismal development muscle organ development
202259_s_at	0.942	6.344	3.120	6.929e-03	0.143	-2.385	N4BP2L2	NEDD4 binding protein 2-like 2	13	-31989029, -31904929	NM_014887	10443	13q13.1	Hs.507680	4	molecular_function cellular_component biological_process
177_at	0.248	3.783	3.119	6.937e-03	0.143	-2.387	PLD1	phospholipase D1, phosphatidylcholine-specific	3	-172801311	U38545	5337	3q26	Hs.382865	84	phospholipase D activity protein binding cytoplasm endosome endoplasmic reticulum Golgi apparatus chemotaxis cell communication Ras protein signal transduction metabolic process membrane lipid catabolic process hydrolase activity phosphoinositide binding perinuclear region of cytoplasm NAPE-specific phospholipase D activity	Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways Endocytosis Fc gamma R-mediated phagocytosis GnRH signaling pathway Pathways in cancer Pancreatic cancer
223109_at	0.400	6.478	3.119	6.941e-03	0.143	-2.387	TRUB2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)	9	-130111216	BC001457	26995	9q34.11	Hs.632685	7	pseudouridine synthesis RNA binding RNA processing tRNA processing pseudouridine synthase activity isomerase activity
205247_at	0.424	6.980	3.119	6.944e-03	0.143	-2.388	NOTCH4	Notch homolog 4 (Drosophila)	6	-32270597, -3569804, -3377584	AI743713	4855	6p21.3	Hs.436100	70	patterning of blood vessels cell fate determination morphogenesis of a branching structure calcium ion binding protein binding extracellular space nucleus plasma membrane integral to plasma membrane Notch signaling pathway JAK-STAT cascade nervous system development brain development aging embryonic development basal plasma membrane cell surface hemopoiesis mammary gland development regulation of transcription negative regulation of endothelial cell differentiation positive regulation of transcription, DNA-dependent protein heterodimerization activity positive regulation of smooth muscle cell proliferation advanced glycation end-product receptor activity regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
235980_at	-0.475	5.834	-3.118	6.956e-03	0.143	-2.389	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	3	180349004	AA767763	5290	3q26.3	Hs.553498 Hs.85701	259	nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex glucose metabolic process protein amino acid phosphorylation anti-apoptosis signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor lamellipodium regulation of multicellular organism growth protein kinase B signaling cascade insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
1557593_at	-0.302	2.788	-3.118	6.961e-03	0.143	-2.390	SPAG17	sperm associated antigen 17	1	-118297810	AA250798	200162	1p12	Hs.528821	7	protein binding cytoplasm microtubule cilium flagellum flagellar axoneme
223694_at	0.375	9.492	3.118	6.963e-03	0.143	-2.390	TRIM7	tripartite motif-containing 7	5	-180562728, -180553529, -180553529, -180553529	AF220032	81786	5q35.3	Hs.487412	7	protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding
223468_s_at	-0.535	7.311	-3.118	6.963e-03	0.143	-2.390	RGMA	RGM domain family, member A	15	-91387640	AL136826	56963	15q26.1	Hs.271277	16	neural tube closure endoplasmic reticulum plasma membrane cell surface regulation of BMP signaling pathway anchored to membrane
212761_at	0.314	7.824	3.116	6.983e-03	0.144	-2.393	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10	114699998	AI949687	6934	10q25.3	Hs.593995	246	blood vessel development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter anti-apoptosis cell cycle arrest beta-catenin binding transcription factor binding cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process specific transcriptional repressor activity protein kinase binding pancreas development positive regulation of insulin secretion regulation of hormone metabolic process glucose homeostasis fat cell differentiation regulation of transcription myoblast cell fate commitment Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
212463_at	-0.375	9.391	-3.116	6.987e-03	0.144	-2.393	CD59	CD59 molecule, complement regulatory protein	11	-33681131, -33681131, -33681131	BE379006	966	11p13	Hs.278573 Hs.709466 Hs.710641	107	protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane	Complement and coagulation cascades Hematopoietic cell lineage
204969_s_at	-0.586	5.074	-3.116	6.990e-03	0.144	-2.394	RDX	radixin	11	-109605375	NM_002906	5962	11q23	Hs.263671 Hs.592679	46	ruffle actin binding cytoplasm cytoskeleton plasma membrane extrinsic to membrane lamellipodium microvillus assembly filopodium stereocilium apical protein localization apical part of cell actin filament capping	Regulation of actin cytoskeleton
201734_at	-0.491	8.373	-3.115	6.994e-03	0.144	-2.394	CLCN3	chloride channel 3	4	170778296	AI760629	1182	4q33	Hs.481186	28	nucleotide binding ion channel activity voltage-gated chloride channel activity protein binding ATP binding early endosome early endosome late endosome late endosome Golgi apparatus Golgi apparatus ion transport chloride transport regulation of pH cell surface vesicle membrane vesicle membrane antiporter activity membrane integral to membrane PDZ domain binding PDZ domain binding chloride ion binding cytoplasmic vesicle protein homodimerization activity protein heterodimerization activity protein heterodimerization activity endosomal lumen acidification
209395_at	0.413	2.365	3.115	6.997e-03	0.144	-2.395	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	1	-201414681	M80927	1116	1q32.1	Hs.382202	71	catalytic activity chitinase activity extracellular matrix structural constituent sugar binding extracellular region proteinaceous extracellular matrix extracellular space carbohydrate metabolic process chitin catabolic process cation binding
201878_at	-0.490	7.485	-3.115	7.001e-03	0.144	-2.395	ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	15	70553720	N25546	25820	15q24	Hs.268787	11	ubiquitin ligase complex protein binding cytoplasm ubiquitin-dependent protein catabolic process zinc ion binding small conjugating protein ligase activity metal ion binding
240449_at	-0.492	5.332	-3.114	7.008e-03	0.144	-2.396	ZNF341	zinc finger protein 341	20	31783468	AW204518	84905	20q11.22	Hs.516989	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203167_at	0.257	4.631	3.114	7.011e-03	0.144	-2.396	TIMP2	TIMP metallopeptidase inhibitor 2	17	-74360653	NM_003255	7077	17q25	Hs.633514	168	enzyme inhibitor activity integrin binding protein binding extracellular region basement membrane enzyme activator activity metalloendopeptidase inhibitor activity negative regulation of cell proliferation cell surface regulation of cAMP metabolic process regulation of MAPKKK cascade regulation of neuron differentiation
218966_at	0.467	6.083	3.114	7.012e-03	0.144	-2.397	MYO5C	myosin VC	15	-50271811	NM_018728	55930	15q21	Hs.487036	6	nucleotide binding motor activity calmodulin binding ATP binding myosin complex actin filament binding
211563_s_at	-0.818	6.715	-3.114	7.019e-03	0.144	-2.397	C19orf2	chromosome 19 open reading frame 2	19	35125264	AB006572	8725	19q12	Hs.466391	11	transcription corepressor activity nucleus DNA-directed RNA polymerase II, core complex cytoplasm regulation of transcription from RNA polymerase II promoter protein folding response to virus prefoldin complex unfolded protein binding
203340_s_at	-0.606	9.488	-3.113	7.023e-03	0.144	-2.398	SLC25A12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	2	-172348160	NM_003705	8604	2q24	Hs.470608	27	transporter activity L-glutamate transmembrane transporter activity calcium ion binding protein binding mitochondrion mitochondrial inner membrane transport L-aspartate transmembrane transporter activity aspartate transport L-glutamate transport membrane integral to membrane malate-aspartate shuttle response to calcium ion
217515_s_at	-0.346	9.542	-3.113	7.030e-03	0.144	-2.399	CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	1	-199275262	AI391509	779	1q32	Hs.1294	33	voltage-gated ion channel activity calcium ion binding cytoplasm plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport muscle contraction high voltage-gated calcium channel activity dihydropyridine-sensitive calcium channel activity integral to membrane T-tubule I band	MAPK signaling pathway Calcium signaling pathway Cardiac muscle contraction Vascular smooth muscle contraction GnRH signaling pathway Alzheimer's disease Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
210982_s_at	0.946	8.024	3.113	7.030e-03	0.144	-2.399	HLA-DRA	major histocompatibility complex, class II, DR alpha	6	32515624, 3814608, 3622461	M60333	3122	6p21.3	Hs.520048	134	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II lysosome plasma membrane plasma membrane integral to plasma membrane immune response MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
228480_at	-0.545	6.708	-3.113	7.034e-03	0.144	-2.399	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	18	9903954	AW296039	9218	18p11.22	Hs.699980	18	signal transducer activity structural molecule activity protein binding membrane fraction endoplasmic reticulum microtubule plasma membrane tight junction membrane fusion integral to membrane vesicle positive regulation of I-kappaB kinase/NF-kappaB cascade protein heterodimerization activity perinuclear region of cytoplasm	Tight junction
221006_s_at	-0.345	5.976	-3.112	7.039e-03	0.144	-2.400	SNX27	sorting nexin family member 27	1	149851285	NM_030918	81609	1q21.3	Hs.192326	13	protein binding cytoplasm early endosome cytosol signal transduction protein transport phosphoinositide binding
215499_at	-0.633	9.338	-3.112	7.040e-03	0.144	-2.400	MAP2K3	mitogen-activated protein kinase kinase 3	17	21128560, 21135373	AA780381	5606	17q11.2	Hs.514012	45	nucleotide binding activation of MAPK activity protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding inflammatory response signal transduction transferase activity regulation of cytokine biosynthetic process positive regulation of protein kinase activity positive regulation of transcription, DNA-dependent cardiac muscle contraction	MAPK signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway GnRH signaling pathway Amyotrophic lateral sclerosis (ALS)
225181_at	-0.630	7.692	-3.112	7.044e-03	0.144	-2.401	ARID1B	AT rich interactive domain 1B (SWI1-like)	6	157140777	BE463648	57492	6q25.1	Hs.291587 Hs.714899	22	DNA binding DNA binding transcription coactivator activity protein binding intracellular nucleus nucleolus cytoplasm SWI/SNF complex chromatin modification regulation of transcription chromatin-mediated maintenance of transcription
238577_s_at	0.341	2.850	3.112	7.046e-03	0.144	-2.401	TSHZ2	teashirt zinc finger homeobox 2	20	51022283	AA628481	128553	20q13.2	Hs.271605 Hs.473117 Hs.649877	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding
203934_at	0.558	6.042	3.112	7.047e-03	0.144	-2.401	KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	4	-55639183	NM_002253	3791	4q11-q12	Hs.479756	264	nucleotide binding angiogenesis ovarian follicle development vasculogenesis positive regulation of mesenchymal cell proliferation receptor activity vascular endothelial growth factor receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation multicellular organismal development regulation of cell shape membrane transferase activity growth factor binding hemopoiesis positive regulation of cell migration surfactant homeostasis interspecies interaction between organisms cell fate commitment endothelial cell differentiation vascular endothelial growth factor receptor signaling pathway lung alveolus development cell maturation branching morphogenesis of a tube positive regulation of epithelial cell proliferation positive regulation of positive chemotaxis calcium ion homeostasis	Cytokine-cytokine receptor interaction Endocytosis VEGF signaling pathway Focal adhesion
210211_s_at	-0.383	11.097	-3.112	7.049e-03	0.144	-2.401	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	AF028832	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
206843_at	-0.286	4.409	-3.111	7.058e-03	0.144	-2.403	CRYBA4	crystallin, beta A4	22	25347927	NM_001886	1413	22q11.2-q13.1 22q12.1	Hs.57690	13	molecular_function structural constituent of eye lens soluble fraction visual perception visual perception camera-type eye development
1553269_at	0.597	3.389	3.110	7.076e-03	0.144	-2.405	ZNF718	zinc finger protein 718	4	43276	CA411757	255403	4p16.3	Hs.428579 Hs.636638	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224942_at	0.314	3.710	3.109	7.083e-03	0.144	-2.406	PAPPA	pregnancy-associated plasma protein A, pappalysin 1	9	117955891	BG434272	5069	9q33.2	Hs.643599 Hs.713596	86	extracellular region extracellular region proteolysis female pregnancy peptidase activity metallopeptidase activity metallopeptidase activity zinc ion binding membrane cell differentiation metal ion binding
203575_at	-0.316	7.110	-3.109	7.083e-03	0.144	-2.406	CSNK2A2	casein kinase 2, alpha prime polypeptide	16	-56749312	NM_001896	1459	16q21	Hs.82201	143	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity protein N-terminus binding regulation of cell cycle	Wnt signaling pathway Adherens junction Tight junction
200836_s_at	-0.407	8.420	-3.109	7.084e-03	0.144	-2.406	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	NM_002375	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
209485_s_at	-0.314	9.487	-3.109	7.090e-03	0.144	-2.407	OSBPL1A	oxysterol binding protein-like 1A	18	-19996008, -19996008	W19983	114876	18q11.1	Hs.370725	12	phospholipid binding intracellular lipid transport steroid metabolic process cholesterol metabolic process vesicle-mediated transport
225793_at	-0.425	7.860	-3.108	7.098e-03	0.144	-2.408	LIX1L	Lix1 homolog (mouse)-like	1	144188441	AW500180	128077	1q21.1	Hs.632435	2
1552899_at	0.474	4.863	3.108	7.102e-03	0.144	-2.408	RP4-662A9.2	hypothetical protein MGC34034	6	134183977	NM_153224	154089	6q23.2	Hs.126165	1
223567_at	0.265	3.275	3.108	7.102e-03	0.144	-2.408	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	19	-4493599	AB022433	10501	19p13.3	Hs.465642	4	receptor activity multicellular organismal development nervous system development membrane integral to membrane cell differentiation	Axon guidance
212041_at	-0.421	8.805	-3.108	7.107e-03	0.144	-2.409	ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	16	-66029417	AL566172	9114	16q22	Hs.106876	21	protein binding ion transport hydrogen-exporting ATPase activity, phosphorylative mechanism ATP synthesis coupled proton transport proton transport membrane vacuolar proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V0 domain	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
219355_at	0.561	5.146	3.107	7.113e-03	0.144	-2.410	CXorf57	chromosome X open reading frame 57	X	105741815	NM_018015	55086	Xq22.3	Hs.274267	5
209234_at	-1.102	7.572	-3.107	7.116e-03	0.144	-2.410	KIF1B	kinesin family member 1B	1	10193350, 10193350	BF939474	23095	1p36.2	Hs.97858	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle
224478_s_at	0.495	7.075	3.107	7.116e-03	0.144	-2.410	C7orf50	chromosome 7 open reading frame 50	7	-1003148	BC006224	84310	7p22.3	Hs.653258	5
217745_s_at	-0.451	10.216	-3.107	7.120e-03	0.144	-2.411	NAT13	N-acetyltransferase 13 (GCN5-related)	3	-114920530	NM_025146	80218	3q13.2	Hs.596074	5	protein binding cytoplasm N-terminal protein amino acid acetylation N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
224514_x_at	0.391	5.304	3.106	7.124e-03	0.144	-2.411	IL17RC	interleukin 17 receptor C	3	9933763	BC006411	84818	3p25.3 3p25.3-p24.1	Hs.129959	14	receptor activity plasma membrane integral to membrane
218120_s_at	0.399	6.908	3.106	7.125e-03	0.144	-2.411	HMOX2	heme oxygenase (decycling) 2	16	4464719, 4466341, 4485859	D21243	3163	16p13.3	Hs.284279	32	response to hypoxia heme oxygenase (decyclizing) activity iron ion binding protein binding endoplasmic reticulum microsome plasma membrane heme oxidation electron carrier activity oxidoreductase activity metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
225030_at	-0.436	8.420	-3.106	7.128e-03	0.144	-2.412	BOD1	biorientation of chromosomes in cell division 1	5	-172966753	AA824341	91272	5q35.2	Hs.425091	4
223016_x_at	-0.465	7.617	-3.106	7.132e-03	0.144	-2.412	ZRANB2	zinc finger, RAN-binding domain containing 2	1	-71301561	AF065392	9406	1p31	Hs.194718	18	transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding
212910_at	-0.462	7.578	-3.105	7.142e-03	0.144	-2.413	THAP11	THAP domain containing 11	16	66433713	W19873	57215	16q22.1	Hs.632200	7	DNA binding nucleus cytoplasm zinc ion binding identical protein binding regulation of transcription metal ion binding
231522_at	0.237	3.777	3.105	7.146e-03	0.144	-2.414	C20orf144	chromosome 20 open reading frame 144	20	31713780	AA776747	128864	20q11.22	Hs.324104	3
231114_at	0.578	2.627	3.105	7.146e-03	0.144	-2.414	SPATA22	spermatogenesis associated 22	17	-3290063	BF438413	84690	17p13.3	Hs.351068	3
206981_at	-0.468	7.705	-3.104	7.154e-03	0.144	-2.415	SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	17	-59369645	NM_000334	6329	17q23-q25.3	Hs.46038	65	voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport muscle contraction membrane sodium ion binding
221189_s_at	0.276	6.993	3.104	7.158e-03	0.144	-2.416	TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	1	148726543	NM_025150	80222	1q21.3	Hs.288974	8	nucleotide binding threonine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix threonyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
212229_s_at	-0.503	8.773	-3.104	7.161e-03	0.144	-2.416	FBXO21	F-box protein 21	12	-116065967	AK001699	23014	12q24.22	Hs.719089	7	ubiquitin ligase complex ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process
1555864_s_at	0.288	10.969	3.104	7.161e-03	0.144	-2.416	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	X	19271931	AW057819	5160	Xp22.2-p22.1	Hs.530331	54	pyruvate dehydrogenase (acetyl-transferring) activity protein binding mitochondrion mitochondrial matrix glycolysis oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
204631_at	-0.830	13.478	-3.104	7.164e-03	0.144	-2.416	MYH2	myosin, heavy chain 2, skeletal muscle, adult	17	-10365189, -10365189	NM_017534	4620	17p13.1	Hs.699445	22	microfilament motor activity nucleotide binding actin binding calmodulin binding ATP binding nucleolus cytoplasm striated muscle thick filament focal adhesion striated muscle contraction structural constituent of muscle myosin complex muscle filament sliding	Tight junction
1557820_at	-0.352	10.500	-3.102	7.188e-03	0.145	-2.419	AFG3L2	AFG3 ATPase family gene 3-like 2 (yeast)	18	-12319107	AA905788	10939	18p11	Hs.528996	5	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion mitochondrial inner membrane proteolysis axonogenesis neuromuscular junction development peptidase activity zinc ion binding membrane integral to membrane death nucleoside-triphosphatase activity nerve development regulation of multicellular organism growth myelination metal ion binding muscle fiber development unfolded protein binding righting reflex
242463_x_at	0.426	3.891	3.102	7.188e-03	0.145	-2.419	ZNF600	zinc finger protein 600	19	-57960559	AI620827	162966	19q13.41	Hs.696848	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
235025_at	-0.348	2.571	-3.102	7.189e-03	0.145	-2.419	WDR89	WD repeat domain 89	14	-63133509, -63133509	AW196959	112840	14q23.2	Hs.655666	6
224574_at	0.442	7.094	3.102	7.190e-03	0.145	-2.420	C17orf49	chromosome 17 open reading frame 49	17	6858796	AV759602	124944	17p13.1	Hs.511801	7	DNA binding nucleus
238332_at	0.508	4.681	3.102	7.191e-03	0.145	-2.420	ANKRD29	ankyrin repeat domain 29	18	-19433975	AI307802	147463	18q11.2	Hs.374774	4
209027_s_at	-0.465	5.959	-3.102	7.191e-03	0.145	-2.420	ABI1	abl-interactor 1	10	-27075530	BF673013	10006	10p11.2	Hs.508148	39	intracellular soluble fraction nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal protein binding negative regulation of cell proliferation peptidyl-tyrosine phosphorylation synaptosome lamellipodium cell junction filopodium growth cone synapse
205422_s_at	0.587	4.355	3.102	7.193e-03	0.145	-2.420	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	13	100902966	NM_004791	9358	13q33	Hs.696554	5	receptor activity binding extracellular region cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex
235049_at	0.412	5.891	3.101	7.199e-03	0.145	-2.421	ADCY1	adenylate cyclase 1 (brain)	7	45580649	AA021120	107	7p13-p12	Hs.192215	24	nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis
1555906_s_at	-0.669	6.472	-3.100	7.212e-03	0.145	-2.422	C3orf23	chromosome 3 open reading frame 23	3	44354614, 44354947, 44354947	AI147556	285343	3p21.31	Hs.55131	8	mitochondrion
214266_s_at	-0.522	7.183	-3.100	7.214e-03	0.145	-2.423	PDLIM7	PDZ and LIM domain 7 (enigma)	5	-176849852, -176843000	AW206786	9260	5q35.3	Hs.533040	22	ossification protein binding cytoplasm cytoskeleton receptor-mediated endocytosis multicellular organismal development zinc ion binding cell differentiation metal ion binding
227530_at	0.498	5.881	3.100	7.215e-03	0.145	-2.423	AKAP12	A kinase (PRKA) anchor protein 12	6	151602826, 151688358	BF511276	9590	6q24-q25	Hs.371240	33	nucleus cytoplasm cytoskeleton plasma membrane cell cortex protein targeting signal transduction G-protein coupled receptor protein signaling pathway protein kinase A binding
223334_at	0.453	10.036	3.100	7.215e-03	0.145	-2.423	TMEM126A	transmembrane protein 126A	11	85036692	AL136941	84233	11q14.1	Hs.533725	8	molecular_function mitochondrion biological_process membrane integral to membrane
221606_s_at	-0.498	5.373	-3.100	7.217e-03	0.145	-2.423	NSBP1	nucleosomal binding protein 1	X	-80255855	BC005342	79366	Xq13.3	Hs.282204	7	chromatin DNA binding chromatin binding nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase I promoter transcription activator activity
230384_at	-0.762	7.912	-3.100	7.221e-03	0.145	-2.424	ANKRD23	ankyrin repeat domain 23	2	-96867377	AI866797	200539	2q11.2	Hs.643430	8	nucleus
204350_s_at	-0.330	7.296	-3.099	7.231e-03	0.145	-2.425	MED7	mediator complex subunit 7	5	-156498028, -156498028	NM_004270	9443	5q33.3	Hs.279902 Hs.719330	15	transcription coactivator activity protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription regulator activity regulation of transcription
234533_at	0.306	4.735	3.099	7.234e-03	0.145	-2.425	BCL2L14	BCL2-like 14 (apoptosis facilitator)	12	12115144, 12115668	AK026440	79370	12p13-p12	Hs.210343	13	protein binding cytoplasm cytosol membrane regulation of apoptosis intracellular organelle
212681_at	0.976	4.830	3.099	7.234e-03	0.145	-2.425	EPB41L3	erythrocyte membrane protein band 4.1-like 3	18	-5382387	AI770004	23136	18p11.32	Hs.213394	39	actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization	Tight junction
203054_s_at	0.333	6.651	3.099	7.235e-03	0.145	-2.425	TCTA	T-cell leukemia translocation altered gene	3	49424642	NM_022171	6988	3p21	Hs.517962	6
226545_at	0.479	5.543	3.099	7.238e-03	0.145	-2.426	CD109	CD109 molecule	6	74462228, 74462234	AL110152	135228	6q13	Hs.399891	24	serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space plasma membrane anchored to membrane
230804_at	-0.446	2.494	-3.099	7.238e-03	0.145	-2.426	NKAPL	NFKB activating protein-like	6	28335076	AA902654	222698	6p22.1	Hs.239181	3
217714_x_at	0.338	6.308	3.099	7.239e-03	0.145	-2.426	STMN1	stathmin 1	1	-26099193, -26099193, -26099193, -26083264	AV756729	3925	1p36.1-p35	Hs.209983	80	signal transducer activity protein binding intracellular cytoplasm microtubule microtubule depolymerization mitotic spindle organization intracellular signaling cascade multicellular organismal development nervous system development tubulin binding membrane integral to membrane cell differentiation	MAPK signaling pathway
226843_s_at	-0.310	6.773	-3.099	7.241e-03	0.145	-2.426	PAPD5	PAP associated domain containing 5	16	48745568	AU146704	64282	16q12.1	Hs.514342	5	molecular_function DNA binding DNA-directed DNA polymerase activity cellular_component nucleus DNA replication cell cycle mitosis biological_process transferase activity nucleotidyltransferase activity cell division
1552739_s_at	-0.262	5.334	-3.098	7.247e-03	0.145	-2.427	ST7L	suppression of tumorigenicity 7 like	1	-112885935, -112867663	NM_138729	54879	1p13.2	Hs.201921	6	membrane integral to membrane
226615_at	-0.405	6.555	-3.098	7.250e-03	0.145	-2.427	XPR1	xenotropic and polytropic retrovirus receptor	1	178867768	BE439489	9213	1q25.1	Hs.227656	6	G-protein coupled receptor activity plasma membrane integral to plasma membrane G-protein coupled receptor protein signaling pathway
232298_at	-0.849	7.873	-3.097	7.258e-03	0.145	-2.428	hCG_1806964	hypothetical LOC401093	3	-153463102	AK026494	401093	3q25.1	Hs.201858 Hs.558914 Hs.719379	3
235260_s_at	-0.665	5.641	-3.097	7.265e-03	0.145	-2.429	PACRGL	PARK2 co-regulated-like	4	20311133	AA398590	133015	4p15.31	Hs.479298	5	binding
206351_s_at	0.338	5.011	3.097	7.266e-03	0.145	-2.429	PEX10	peroxisomal biogenesis factor 10	1	-2326100	NM_002617	5192	1p36.32	Hs.591454	16	protein binding peroxisome peroxisomal membrane peroxisome organization zinc ion binding membrane protein import into peroxisome matrix metal ion binding
204123_at	0.286	5.467	3.096	7.278e-03	0.145	-2.431	LIG3	ligase III, DNA, ATP-dependent	17	30331650, 30331650	NM_013975	3980	17q11.2-q12	Hs.100299	45	nucleotide binding magnesium ion binding DNA binding DNA ligase (ATP) activity protein binding ATP binding intracellular nucleus nucleoplasm DNA replication DNA repair response to DNA damage stimulus cell cycle reciprocal meiotic recombination spermatogenesis zinc ion binding ligase activity V(D)J recombination cell division	Base excision repair
203016_s_at	-0.568	5.926	-3.096	7.279e-03	0.145	-2.431	SSX2IP	synovial sarcoma, X breakpoint 2 interacting protein	1	-84882184	AK001710	117178	1p22.3	Hs.22587	14	protein binding nucleus adherens junction cell adhesion cell junction protein complex	Adherens junction
212465_at	-0.423	9.209	-3.096	7.280e-03	0.145	-2.431	SETD3	SET domain containing 3	14	-98945893, -98933835	AA524500	84193	14q32.2	Hs.510407	6
204496_at	-0.452	8.897	-3.096	7.283e-03	0.145	-2.431	STRN3	striatin, calmodulin binding protein 3	14	-30432755	NM_014574	29966	14q13-q21	Hs.21016 Hs.401843	13	calmodulin binding membrane fraction nucleus cytoplasm cytosol cell cycle membrane
225063_at	0.362	7.547	3.096	7.284e-03	0.145	-2.432	UBL7	ubiquitin-like 7 (bone marrow stromal cell-derived)	15	-72525370, -72525370	BF568780	84993	15q24.1	Hs.334713	7	protein binding modification-dependent protein catabolic process
204352_at	0.446	4.857	3.095	7.290e-03	0.145	-2.432	TRAF5	TNF receptor-associated factor 5	1	209566579, 209566770, 209586328	NM_004619	7188	1q32	Hs.523930	52	signal transducer activity protein binding cytoplasm centrosome signal transduction zinc ion binding positive regulation of cell proliferation regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	Pathways in cancer Small cell lung cancer
1553113_s_at	-0.666	5.357	-3.094	7.301e-03	0.145	-2.434	CDK8	cyclin-dependent kinase 8	13	25726755	BF700678	1024	13q12	Hs.382306	38	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation RNA polymerase II carboxy-terminal domain kinase activity transferase activity regulation of transcription
55872_at	0.506	6.330	3.094	7.301e-03	0.145	-2.434	ZNF512B	zinc finger protein 512B	20	-62058498	AI493119	57473	20q13.33	Hs.551552	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
200999_s_at	0.484	7.516	3.094	7.310e-03	0.145	-2.435	CKAP4	cytoskeleton-associated protein 4	12	-105155789	NM_006825	10970	12q23.3	Hs.714862 Hs.74368	22	membrane fraction endoplasmic reticulum membrane integral to membrane
203071_at	0.307	5.086	3.094	7.310e-03	0.145	-2.435	SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	3	50280043	NM_004636	7869	3p21.3	Hs.82222	22	receptor activity extracellular region endoplasmic reticulum cell-cell signaling multicellular organismal development axon guidance membrane	Axon guidance
222826_at	-0.518	6.780	-3.093	7.325e-03	0.145	-2.437	PLDN	pallidin homolog (mouse)	15	43666708	BC004819	26258	15q21.1	Hs.719102	17	cellular_component cytoplasm endosome membrane fusion blood coagulation membrane synaptic vesicle docking during exocytosis melanocyte differentiation syntaxin-13 binding positive regulation of natural killer cell activation secretion of lysosomal enzymes identical protein binding pigmentation
210203_at	-0.666	5.704	-3.093	7.325e-03	0.145	-2.437	CNOT4	CCR4-NOT transcription complex, subunit 4	7	-134723303, -134697088	R64001	4850	7q22-qter	Hs.490224	7	nucleotide binding RNA binding protein binding nucleus cytoplasm zinc ion binding ligase activity modification-dependent protein catabolic process regulation of transcription metal ion binding	RNA degradation
45526_g_at	-0.483	8.498	-3.092	7.346e-03	0.146	-2.439	NAT15	N-acetyltransferase 15 (GCN5-related, putative)	16	3433668, 3447992	AI246641	79903	16p13.3	Hs.513296	6	N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
225878_at	-0.481	11.479	-3.091	7.351e-03	0.146	-2.440	KIF1B	kinesin family member 1B	1	10193350, 10193350	AL135264	23095	1p36.2	Hs.97858	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle
207543_s_at	-0.570	8.070	-3.091	7.353e-03	0.146	-2.440	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	10	-74436987	NM_000917	5033	10q21.3-q23.1	Hs.500047 Hs.593005	19	procollagen-proline 4-dioxygenase activity binding iron ion binding mitochondrion endoplasmic reticulum endoplasmic reticulum lumen oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Arginine and proline metabolism Metabolic pathways
221227_x_at	0.309	8.085	3.091	7.355e-03	0.146	-2.440	COQ3	coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	6	-99924068	NM_017421	51805	6q16.2	Hs.713623	6	hexaprenyldihydroxybenzoate methyltransferase activity mitochondrion mitochondrial matrix glycerol metabolic process ubiquinone biosynthetic process metabolic process O-methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity transferase activity	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
1553387_at	-0.301	3.118	-3.091	7.359e-03	0.146	-2.441	ATM	ataxia telangiectasia mutated	11	107598768, 107663328	NM_138293	472	11q22-q23	Hs.367437	504	nucleotide binding DNA binding protein serine/threonine kinase activity ATP binding nucleus nucleoplasm DNA repair response to DNA damage stimulus cell cycle mitotic cell cycle spindle assembly checkpoint reciprocal meiotic recombination signal transduction cell death response to ionizing radiation 1-phosphatidylinositol-3-kinase activity transferase activity cytoplasmic vesicle protein N-terminus binding	Cell cycle p53 signaling pathway Apoptosis
1567458_s_at	-0.712	7.595	-3.090	7.363e-03	0.146	-2.441	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	AJ012502	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
218611_at	-0.887	7.569	-3.090	7.368e-03	0.146	-2.442	IER5	immediate early response 5	1	179324260	NM_016545	51278	1q25.3	Hs.716489	8
241208_at	-1.053	6.986	-3.090	7.368e-03	0.146	-2.442	PDLIM5	PDZ and LIM domain 5	4	95592060, 95592060	AI808578	10611	4q22	Hs.480311	34	actin binding protein kinase C binding protein binding membrane fraction cytosol zinc ion binding actin cytoskeleton Z disc actinin binding metal ion binding
226776_at	-0.896	6.247	-3.090	7.371e-03	0.146	-2.442	ENY2	enhancer of yellow 2 homolog (Drosophila)	8	110415811	BF433516	56943	8q23.1	Hs.492555	5	SAGA complex nucleus transport chromatin modification histone deubiquitination ligand-dependent nuclear receptor transcription coactivator activity regulation of transcription positive regulation of transcription, DNA-dependent mRNA transport
204512_at	-0.364	4.667	-3.090	7.373e-03	0.146	-2.443	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	6	12120709	NM_002114	3096	6p24-p22.3	Hs.567284	16	DNA binding protein binding intracellular nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding
202449_s_at	-0.458	8.557	-3.090	7.374e-03	0.146	-2.443	RXRA	retinoid X receptor, alpha	9	136358136	NM_002957	6256	9q34.3	Hs.590886	190	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription coactivator activity retinoid-X receptor activity steroid binding protein binding nucleus regulation of transcription, DNA-dependent vitamin metabolic process cholesterol metabolic process zinc ion binding response to retinoic acid vitamin D receptor binding sequence-specific DNA binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter metal ion binding retinoic acid receptor signaling pathway ventricular cardiac muscle morphogenesis ventricular cardiac muscle cell differentiation cardiac muscle cell proliferation vitamin D response element binding	PPAR signaling pathway Adipocytokine signaling pathway Pathways in cancer Thyroid cancer Small cell lung cancer Non-small cell lung cancer
207618_s_at	0.335	7.659	3.090	7.375e-03	0.146	-2.443	BCS1L	BCS1-like (yeast)	2	219232622	NM_004328	617	2q33	Hs.471401	20	nucleotide binding protein binding ATP binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex III mitochondrion organization membrane integral to membrane nucleoside-triphosphatase activity mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex IV assembly mitochondrial respiratory chain complex III assembly
220938_s_at	-0.233	6.164	-3.089	7.377e-03	0.146	-2.443	GMEB1	glucocorticoid modulatory element binding protein 1	1	28867830, 28867830	NM_006582	10691	1p35.3	Hs.632373	18	DNA binding transcription coactivator activity binding nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding
1556325_at	-0.575	8.240	-3.089	7.382e-03	0.146	-2.444	FILIP1	filamin A interacting protein 1	6	-76074519	AL832009	27145	6q14.1	Hs.696158	9
234851_at	0.250	4.052	3.089	7.387e-03	0.146	-2.444	IGL@	immunoglobulin lambda locus	22		AJ275399	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
230327_at	0.353	5.981	3.089	7.387e-03	0.146	-2.444	LOC730098	similar to chemokine (C-C motif) ligand 27	9		AI203673	730098	9p13.3	Hs.459590
211352_s_at	-0.649	5.796	-3.089	7.387e-03	0.146	-2.444	NCOA3	nuclear receptor coactivator 3	20	45564063	U80737	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
225348_at	-0.839	5.340	-3.089	7.389e-03	0.146	-2.445	FUSIP1	FUS interacting protein (serine/arginine-rich) 1	1	-24168159, -24165525, -1503240, -1500603	AI954700	10772	1p36.11	Hs.3530 Hs.652334	22	nucleotide binding assembly of spliceosomal tri-snRNP RNA binding nucleus nucleoplasm cytoplasm mRNA splice site selection mRNA splice site selection mRNA export from nucleus RNA splicing cytoplasmic transport nuclear speck RNA splicing factor activity, transesterification mechanism regulation of transcription negative regulation of nuclear mRNA splicing, via spliceosome RS domain binding unfolded protein binding
224774_s_at	0.321	4.996	3.088	7.395e-03	0.146	-2.445	NAV1	neuron navigator 1	1	199884072	AK022622	89796	1q32.3	Hs.585374	10	nucleotide binding cytoplasm cytoskeleton microtubule multicellular organismal development nervous system development nucleoside-triphosphatase activity cell differentiation
225550_at	-0.721	7.294	-3.088	7.401e-03	0.146	-2.446	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	AV700816	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
1562903_at	-0.441	4.554	-3.088	7.403e-03	0.146	-2.446	hCG_1990547	family with sequence similarity 86, member A pseudogene	8	8123501, 8123501, 8123501	BC035792	286042	8p23.1	Hs.656318	2
200916_at	0.534	7.431	3.088	7.405e-03	0.146	-2.447	TAGLN2	transgelin 2	1	-158154526	NM_003564	8407	1q21-q25	Hs.517168	12	protein binding plasma membrane muscle organ development nuclear membrane
223368_s_at	0.327	8.628	3.088	7.405e-03	0.146	-2.447	METTL11A	methyltransferase like 11A	9	131428255	BC001396	28989	9q34.11	Hs.522433	5	protein binding methyltransferase activity transferase activity
240172_at	-0.628	5.537	-3.087	7.420e-03	0.146	-2.449	ERGIC2	ERGIC and golgi 2	12	-29384845	AA102332	51290	12p11.22	Hs.339453	11	nucleus cytoplasm endoplasmic reticulum Golgi apparatus membrane integral to membrane vesicle-mediated transport
235489_at	0.590	5.051	3.086	7.424e-03	0.146	-2.449	RHOJ	ras homolog gene family, member J	14	62740897	AI583530	57381	14q23.2	Hs.656339	8	nucleotide binding GTPase activity protein binding GTP binding cellular_component intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape actin cytoskeleton organization
225516_at	-0.770	9.310	-3.086	7.430e-03	0.146	-2.450	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	8	17440664, 17445205	AA876372	6542	8p22-p21.3	Hs.448520	10	membrane fraction integral to plasma membrane cellular amino acid metabolic process transport amino acid transport basic amino acid transmembrane transporter activity membrane
1552417_a_at	-0.948	4.978	-3.085	7.437e-03	0.146	-2.451	NEDD1	neural precursor cell expressed, developmentally down-regulated 1	12	95825131, 95825374	NM_152905	121441	12q23.1	Hs.270084	10	pericentriolar material spindle pole cytoplasm centriole microtubule basal body cell cycle mitosis apical part of cell cell division
206955_at	0.504	6.920	3.085	7.443e-03	0.146	-2.451	AQP7	aquaporin 7	9	-33374947	NM_001170	364	9p13	Hs.455323	15	transporter activity integral to plasma membrane generation of precursor metabolites and energy transport water transport excretion water channel activity glycerol channel activity glycerol transport membrane	PPAR signaling pathway
200821_at	-0.433	9.961	-3.085	7.451e-03	0.146	-2.452	LAMP2	lysosomal-associated membrane protein 2	X	-119454376, -119444030	NM_013995	3920	Xq24	Hs.496684	52	membrane fraction lysosomal membrane late endosome plasma membrane plasma membrane integral to membrane platelet dense granule membrane platelet dense granule membrane	Lysosome
1555278_a_at	-0.397	6.539	-3.084	7.454e-03	0.146	-2.453	CKAP5	cytoskeleton associated protein 5	11	-46721659	BC035554	9793	11p11.2	Hs.201253	16	gamma-tubulin complex protein binding centrosome cell cycle mitosis microtubule cytoskeleton establishment or maintenance of microtubule cytoskeleton polarity RNA transport centrosome organization spindle pole body organization cell division
207773_x_at	-0.349	3.682	-3.084	7.458e-03	0.146	-2.453	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	7	99263571	NM_022820	64816	7q21.1	Hs.306220 Hs.654391 Hs.695915	17	endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	gamma-Hexachlorocyclohexane degradation Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
233558_s_at	-0.546	5.746	-3.084	7.461e-03	0.146	-2.454	C4orf41	chromosome 4 open reading frame 41	4	184817439	AK023390	60684	4q35.1	Hs.443240	6
218440_at	0.355	7.233	3.084	7.466e-03	0.146	-2.454	MCCC1	methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)	3	-184215699	NM_020166	56922	3q27	Hs.47649	13	nucleotide binding methylcrotonoyl-CoA carboxylase activity ATP binding mitochondrion mitochondrial matrix Golgi apparatus leucine catabolic process biotin metabolic process metabolic process biotin binding ligase activity	Valine, leucine and isoleucine degradation Metabolic pathways
221272_s_at	-0.741	7.422	-3.083	7.471e-03	0.146	-2.455	C1orf21	chromosome 1 open reading frame 21	1	182622772	NM_030806	81563	1q25	Hs.497159 Hs.719188	8
239623_at	0.435	5.536	3.083	7.471e-03	0.146	-2.455	FLJ44606	glutaredoxin-like protein YDR286C homolog	5		N93197	401207	5q23.2	Hs.49573	1	transport electron transport chain
239250_at	0.652	6.194	3.083	7.475e-03	0.146	-2.455	ZNF542	zinc finger protein 542	19	61571279, 61571476	BE966038	147947	19q13.43	Hs.467326	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
239189_at	0.259	4.943	3.083	7.480e-03	0.146	-2.456	CASKIN1	CASK interacting protein 1	16	-2167184	BF090347	57524	16p13.3	Hs.643537	3	protein binding cytoplasm signal transduction
201573_s_at	-0.389	8.422	-3.082	7.484e-03	0.146	-2.456	ETF1	eukaryotic translation termination factor 1	5	-137869682	M75715	2107	5q31.1	Hs.483494	32	RNA binding protein binding cytoplasm regulation of translational termination protein amino acid methylation translation release factor activity, codon specific ribosome binding
223380_s_at	-0.498	7.621	-3.082	7.487e-03	0.146	-2.457	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	13	-20445175	AF207547	26524	13q11-q12	Hs.78960	17	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding spindle pole protein serine/threonine kinase activity ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation cell cycle mitosis protein kinase cascade hormone-mediated signaling transferase activity negative regulation of cyclin-dependent protein kinase activity cell division
203908_at	-0.581	5.255	-3.082	7.494e-03	0.146	-2.458	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	4	72271866, 72423633	NM_003759	8671	4q21	Hs.5462	45	transporter activity inorganic anion exchanger activity plasma membrane integral to plasma membrane sodium ion transport anion transport anion transmembrane transporter activity sodium:bicarbonate symporter activity symporter activity sodium ion binding
206853_s_at	-0.294	6.486	-3.081	7.504e-03	0.146	-2.459	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AL121964	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
219279_at	0.274	3.358	3.080	7.518e-03	0.147	-2.461	DOCK10	dedicator of cytokinesis 10	2	-225338050	NM_017718	55619	2q36.2	Hs.46578	12	guanyl-nucleotide exchange factor activity GTP binding GTPase binding
201241_at	-0.429	9.959	-3.080	7.520e-03	0.147	-2.461	DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	2	15649220	NM_004939	1653	2p24	Hs.440599	24	nucleotide binding spliceosome assembly RNA binding RNA helicase activity protein binding ATP binding cellular_component regulation of translational initiation multicellular organismal development ATP-dependent helicase activity hydrolase activity ribonucleoprotein complex
235415_at	-0.458	5.761	-3.079	7.540e-03	0.147	-2.463	RPRD2	regulation of nuclear pre-mRNA domain containing 2	1	148603613	BE781857	23248	1q21.3	Hs.213666	9	protein binding
206782_s_at	0.302	7.138	3.079	7.541e-03	0.147	-2.463	DNAJC4	DnaJ (Hsp40) homolog, subfamily C, member 4	11	63754328	NM_005528	3338	11q13	Hs.172847	4	membrane fraction protein folding response to unfolded protein membrane integral to membrane heat shock protein binding unfolded protein binding
201588_at	-0.238	10.440	-3.078	7.546e-03	0.147	-2.464	TXNL1	thioredoxin-like 1	18	-52421050	NM_004786	9352	18q21.31	Hs.114412	15	cytoplasm transport disulfide oxidoreductase activity electron transport chain cell redox homeostasis
1554479_a_at	-0.442	7.175	-3.078	7.549e-03	0.147	-2.464	CARD8	caspase recruitment domain family, member 8	19	-53403154	AF511652	22900	19q13.33	Hs.446146 Hs.655940	23	protein binding intracellular nucleus cytoplasm caspase activator activity NACHT domain binding protein homodimerization activity regulation of apoptosis negative regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of caspase activity positive regulation of interleukin-1 beta secretion
202335_s_at	-0.366	2.872	-3.078	7.550e-03	0.147	-2.465	UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	5	133734768	NM_003337	7320	5q23-q31	Hs.615284 Hs.644421	23	nucleotide binding protein polyubiquitination chromatin ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus replication fork cytoplasm plasma membrane postreplication repair postreplication repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein monoubiquitination response to DNA damage stimulus spermatogenesis sperm axoneme assembly response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination response to drug protein stabilization regulation of protein metabolic process protein autoubiquitination Wnt receptor signaling pathway through beta-catenin	Ubiquitin mediated proteolysis
227834_at	-0.613	9.571	-3.078	7.552e-03	0.147	-2.465	TXLNB	taxilin beta	6	-139602893	AL589605	167838	6q24.1	Hs.535820	12	cytoplasm
1552315_at	0.345	5.820	3.078	7.560e-03	0.147	-2.466	GIMAP1	GTPase, IMAP family member 1	7	150044630	NM_130759	170575	7q36.1	Hs.647087	7	GTP binding endoplasmic reticulum membrane integral to membrane
230475_at	0.409	5.722	3.078	7.560e-03	0.147	-2.466	C15orf59	chromosome 15 open reading frame 59	15	-71819193	AI368415	388135	15q24.1	Hs.40794	1
230221_at	0.350	5.927	3.077	7.564e-03	0.147	-2.466	BAT5	HLA-B associated transcript 5	6	-31762714, -3100861, -2902325	AI139010	7920	6p21.3	Hs.388188	14	protein binding cytosol defense response response to unfolded protein response to nutrient membrane integral to membrane protein complex NF-kappaB binding
1559388_a_at	-0.295	5.583	-3.077	7.575e-03	0.147	-2.467	LYNX1	Ly6/neurotoxin 1	8	-143849616, -143849616, -143849616, -143842759, -143842757	BG701653	66004	8q24.3	Hs.158665 Hs.604828	9	extracellular region plasma membrane anchored to membrane
217348_x_at	0.292	6.547	3.076	7.580e-03	0.147	-2.468	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15	17	8154314	AK023853	22899	17p13.1	Hs.443109	7	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity intracellular regulation of Rho protein signal transduction
243179_at	0.660	4.889	3.076	7.587e-03	0.147	-2.469	LOC100130360	hypothetical LOC100130360	6		BG231554	100130360	6p22.3
1552664_at	-0.478	6.210	-3.076	7.591e-03	0.147	-2.469	FLCN	folliculin	17	-17065209, -17056251	NM_144997	201163	17p11.2	Hs.513975	32	protein binding cytoplasm	Renal cell carcinoma
219854_at	0.451	5.260	3.075	7.606e-03	0.147	-2.471	ZNF14	zinc finger protein 14	19	-19682280	NM_021030	7561	19p13.3-p13.2	Hs.659932	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1565651_at	0.264	5.516	3.074	7.609e-03	0.147	-2.472	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	BI868311	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
227186_s_at	0.550	11.233	3.074	7.610e-03	0.147	-2.472	MRPL41	mitochondrial ribosomal protein L41	9	139566129	AI090841	64975	9q34.3	Hs.44017	10	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation apoptosis cell cycle
212918_at	-0.382	6.481	-3.074	7.612e-03	0.147	-2.472	RECQL	RecQ protein-like (DNA helicase Q1-like)	12	-21513111	AI962943	5965	12p12	Hs.235069	29	nucleotide binding DNA strand renaturation DNA strand annealing activity DNA binding ATP-dependent DNA helicase activity protein binding ATP binding nucleus DNA repair DNA recombination hydrolase activity
223915_at	0.539	5.052	3.074	7.613e-03	0.147	-2.472	BCOR	BCL6 co-repressor	X	-39795442, -39795442	AF317392	54880	Xp21.2-p11.4	Hs.659681	19	transcription corepressor activity transcription corepressor activity ubiquitin-protein ligase activity nucleus heart development transcription factor binding chromatin modification heat shock protein binding PcG protein complex odontogenesis histone deacetylase binding negative regulation of transcription, DNA-dependent palate development specification of axis polarity
213638_at	0.243	2.696	3.074	7.614e-03	0.147	-2.472	PHACTR1	phosphatase and actin regulator 1	6	12825818	AW054711	221692	6p24.1	Hs.436996	8	actin binding phosphoprotein phosphatase inhibitor activity cytoplasm cell junction synapse
219504_s_at	-0.292	5.810	-3.074	7.617e-03	0.147	-2.473	RPAP2	RNA polymerase II associated protein 2	1	92537109	NM_024813	79871	1p22.1	Hs.444421	7	membrane integral to membrane
1552785_at	0.327	2.742	3.074	7.619e-03	0.147	-2.473	ZNF781	zinc finger protein 781	19	-42850489	NM_152605	163115	19q13.12	Hs.116622	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1555799_at	-0.365	3.456	-3.074	7.622e-03	0.147	-2.473	FCRL5	Fc receptor-like 5	1	-155749790	AL834187	83416	1q21	Hs.415950	15	receptor activity plasma membrane integral to membrane
221821_s_at	-0.633	7.843	-3.072	7.647e-03	0.148	-2.476	C12orf41	chromosome 12 open reading frame 41	12	-47333261	AK022732	54934	12q13.11	Hs.505412	8
230143_at	0.558	5.047	3.072	7.650e-03	0.148	-2.477	RNF165	ring finger protein 165	18	42168184	BF433220	494470	18q21.1	Hs.501114	4	protein binding zinc ion binding metal ion binding
235978_at	1.140	6.208	3.072	7.651e-03	0.148	-2.477	FABP4	fatty acid binding protein 4, adipocyte	8	-82553286	AI766029	2167	8q21	Hs.391561	44	cytokine production transporter activity fatty acid binding protein binding soluble fraction nucleus cytoplasm cytosol negative regulation of protein kinase activity fatty acid metabolic process transport positive regulation of cell proliferation negative regulation of transcription transcription repressor activity response to drug cholesterol homeostasis positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation response to glucocorticoid stimulus	PPAR signaling pathway
243042_at	-0.481	5.596	-3.070	7.679e-03	0.148	-2.480	FAM73A	family with sequence similarity 73, member A	1	78017896	BE645144	374986	1p31.1	Hs.632419	1	membrane integral to membrane
239412_at	0.379	4.870	3.070	7.684e-03	0.148	-2.481	IRF5	interferon regulatory factor 5	7	128365229, 128365506, 128368007	BF223643	3663	7q32	Hs.521181	63	transcription factor activity nucleus regulation of transcription, DNA-dependent	Toll-like receptor signaling pathway
205607_s_at	-0.356	6.109	-3.069	7.692e-03	0.148	-2.482	SCYL3	SCY1-like 3 (S. cerevisiae)	1	-168088427	NM_020423	57147	1q24.2	Hs.435560	11	protein kinase activity protein binding ATP binding cytoplasm Golgi apparatus protein amino acid phosphorylation cell migration lamellipodium
202811_at	-0.342	8.074	-3.069	7.693e-03	0.148	-2.482	STAMBP	STAM binding protein	2	73909593, 73909634, 73909654	NM_006463	10617	2p13.1	Hs.469018 Hs.657598	28	ubiquitin thiolesterase activity protein binding nucleus cytoplasm early endosome anti-apoptosis JAK-STAT cascade peptidase activity metallopeptidase activity zinc ion binding positive regulation of cell proliferation membrane modification-dependent protein catabolic process metal ion binding	Endocytosis
212651_at	-1.435	8.536	-3.069	7.694e-03	0.148	-2.482	RHOBTB1	Rho-related BTB domain containing 1	10	-62299205, -62299205, -62299205	AB018283	9886	10q21.2	Hs.148670	10	nucleotide binding protein binding GTP binding intracellular small GTPase mediated signal transduction
205222_at	1.049	4.020	3.069	7.698e-03	0.148	-2.482	EHHADH	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	3	-186391105	NM_001966	1962	3q26.3-q28	Hs.429879	9	3-hydroxyacyl-CoA dehydrogenase activity dodecenoyl-CoA delta-isomerase activity enoyl-CoA hydratase activity binding mitochondrion peroxisome lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity lyase activity isomerase activity coenzyme binding oxidation reduction	Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Metabolic pathways PPAR signaling pathway
238929_at	-0.347	5.174	-3.068	7.705e-03	0.148	-2.483	SFRS2B	splicing factor, arginine/serine-rich 2B	11	94439703	N30132	10929	11q22	Hs.476680 Hs.713908	6	nucleotide binding RNA binding nucleus mRNA processing RNA splicing
235867_at	-0.550	6.134	-3.068	7.713e-03	0.148	-2.484	GSTM3	glutathione S-transferase mu 3 (brain)	1	-110078076	AI459140	2947	1p13.3	Hs.2006	96	glutathione transferase activity cytoplasm establishment of blood-nerve barrier metabolic process transferase activity identical protein binding response to estrogen stimulus	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
214805_at	0.347	5.588	3.067	7.718e-03	0.148	-2.485	EIF4A1	eukaryotic translation initiation factor 4A, isoform 1	17	7416780	U79273	1973	17p13	Hs.129673	28	nucleotide binding RNA cap binding mRNA binding translation initiation factor activity helicase activity protein binding ATP binding cytosol translation ATP-dependent helicase activity eukaryotic translation initiation factor 4F complex hydrolase activity
219233_s_at	0.231	5.366	3.067	7.720e-03	0.148	-2.485	GSDMB	gasdermin B	17	-35314373, -35314373	NM_018530	55876	17q12	Hs.306777	12	cytoplasm
218829_s_at	-0.344	6.856	-3.067	7.724e-03	0.148	-2.485	CHD7	chromodomain helicase DNA binding protein 7	8	61753892	NM_017780	55636	8q12.1-q12.2	Hs.20395	36	nucleotide binding chromatin skeletal system development blood vessel development in utero embryonic development heart morphogenesis DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly central nervous system development adult heart development sensory perception of sound locomotory behavior adult walking behavior blood circulation chromatin modification hydrolase activity cranial nerve development T cell differentiation female genitalia development embryonic hindlimb morphogenesis positive regulation of multicellular organism growth inner ear morphogenesis nose development regulation of transcription cognition palate development retina development in camera-type eye regulation of growth hormone secretion limb development face development
241800_x_at	0.248	6.368	3.067	7.730e-03	0.148	-2.486	ZMYM2	zinc finger, MYM-type 2	13	19430809	AA812691	7750	13q11-q12	Hs.644041	29	protein binding cellular_component nucleus biological_process zinc ion binding PML body ubiquitin conjugating enzyme binding regulation of transcription metal ion binding
224597_at	-0.343	10.927	-3.066	7.736e-03	0.148	-2.487	LOC647979	hypothetical LOC647979	20	-34096955	AV729406	647979	20q11.23	Hs.649310 Hs.718413	2
201455_s_at	-0.470	8.739	-3.066	7.743e-03	0.149	-2.488	NPEPPS	aminopeptidase puromycin sensitive	17	42963442	AJ132583	9520	17q21	Hs.443837	14	aminopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
238012_at	0.433	5.615	3.066	7.747e-03	0.149	-2.488	DPP7	dipeptidyl-peptidase 7	9	-139124812	AI620209	29952	9q34.3	Hs.37916	15	aminopeptidase activity protein binding lysosome proteolysis peptidase activity serine-type peptidase activity cytoplasmic vesicle
214755_at	0.439	3.884	3.065	7.749e-03	0.149	-2.488	UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	9	139091773	AK022632	91373	9q34.3	Hs.142076	2	metabolic process transferase activity nucleotidyltransferase activity
229173_at	-0.678	5.966	-3.065	7.756e-03	0.149	-2.489	KIAA1715	KIAA1715	2	-176498655	N29672	80856	2q31	Hs.209561	7	protein binding multicellular organismal development membrane integral to membrane limb development
1555380_at	-0.285	5.536	-3.064	7.776e-03	0.149	-2.492	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	1	-159426161	BC030812	9507	1q21-q23	Hs.211604	56	skeletal system development protease binding metalloendopeptidase activity extracellular region proteinaceous extracellular matrix extracellular space proteolysis peptidase activity zinc ion binding metal ion binding
235292_at	0.392	2.774	3.064	7.780e-03	0.149	-2.492	FLJ32255	hypothetical protein LOC643977	5		BE875232	643977	5p12	Hs.535791	1
209264_s_at	0.346	6.099	3.063	7.785e-03	0.149	-2.493	TSPAN4	tetraspanin 4	11	832823, 832940, 834080, 834445	AF054841	7106	11p15.5	Hs.654836	12	protein binding plasma membrane integral to plasma membrane protein complex assembly
221269_s_at	0.394	6.278	3.063	7.788e-03	0.149	-2.493	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	1	26478799	NM_031286	83442	1p35-p34.3	Hs.109051	8	nucleus cytoplasm electron carrier activity protein disulfide oxidoreductase activity cell redox homeostasis
209297_at	-0.543	7.756	-3.063	7.790e-03	0.149	-2.493	ITSN1	intersectin 1 (SH3 domain protein)	21	33936653, 33936653	AF114488	6453	21q22.1-q22.2	Hs.160324	39	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular intracellular signaling cascade membrane synaptosome lamellipodium cell junction regulation of Rho protein signal transduction synapse synaptic vesicle endocytosis
202536_at	-0.530	7.541	-3.063	7.793e-03	0.149	-2.494	CHMP2B	chromatin modifying protein 2B	3	87359102	AK002165	25978	3p11.2	Hs.476930	36	intracellular cytoplasm endosome cytosol protein transport membrane protein domain specific binding	Endocytosis
202583_s_at	-0.580	6.875	-3.062	7.808e-03	0.149	-2.495	RANBP9	RAN binding protein 9	6	-13729708	NM_005493	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
240310_at	-0.480	5.372	-3.061	7.813e-03	0.149	-2.496	TOR1AIP1	torsin A interacting protein 1	1	178118042	AI807835	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
207121_s_at	-0.593	9.189	-3.061	7.824e-03	0.149	-2.497	MAPK6	mitogen-activated protein kinase 6	15	50098702	NM_002748	5597	15q21	Hs.411847	16	nucleotide binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation cell cycle signal transduction transferase activity
226871_s_at	-0.432	6.652	-3.058	7.864e-03	0.150	-2.502	ATG4D	ATG4 autophagy related 4 homolog D (S. cerevisiae)	19	10515646	BF791801	84971	19p13.2	Hs.512799	6	cysteine-type endopeptidase activity cytoplasm microtubule associated complex protein targeting to vacuole autophagy microtubule binding peptidase activity protein transport modification-dependent protein catabolic process	Regulation of autophagy
209586_s_at	-0.367	7.584	-3.058	7.865e-03	0.150	-2.502	PRUNE	prune homolog (Drosophila)	1	149247596	AF123539	58497	1q21	Hs.78524	8	inorganic diphosphatase activity protein binding nucleus cytoplasm focal adhesion hydrolase activity cell junction manganese ion binding metal ion binding	Purine metabolism
1559957_a_at	0.343	2.809	3.058	7.868e-03	0.150	-2.502	LOC642852	hypothetical LOC642852	21	45532394	BG396868	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
226008_at	-0.333	7.262	-3.057	7.890e-03	0.150	-2.505	NDNL2	necdin-like 2	15	-27347649	AA627644	56160	15q13.1	Hs.719283	8	protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of growth
201595_s_at	-0.371	8.667	-3.057	7.892e-03	0.150	-2.505	ZC3H15	zinc finger CCCH-type containing 15	2	187059129	NM_018471	55854	2q32.1	Hs.368598	3	nucleic acid binding nucleus cytoplasm zinc ion binding cytokine-mediated signaling pathway metal ion binding
243010_at	-0.381	4.275	-3.057	7.893e-03	0.150	-2.505	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BE000929	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
212003_at	-0.269	6.891	-3.056	7.900e-03	0.150	-2.506	C1orf144	chromosome 1 open reading frame 144	1	16566169	BG171020	26099	1p36.13	Hs.252967	2
229487_at	0.576	5.906	3.056	7.907e-03	0.150	-2.507	EBF1	early B-cell factor 1	5	-158055500	W73890	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
241370_at	-0.509	7.686	-3.055	7.916e-03	0.150	-2.508	LOC286052	hypothetical protein LOC286052	8		AA278233	286052	8q24.13	Hs.100691	1
223050_s_at	-0.331	7.869	-3.055	7.923e-03	0.151	-2.509	FBXW5	F-box and WD repeat domain containing 5	9	-138954707	BC000850	54461	9q34.3	Hs.522507	12	protein binding modification-dependent protein catabolic process
222859_s_at	0.490	4.120	3.054	7.926e-03	0.151	-2.509	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	AA150186	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
223049_at	-0.352	7.509	-3.054	7.935e-03	0.151	-2.510	GRB2	growth factor receptor-bound protein 2	17	-70825751, -70825751	AF246238	2885	17q24-q25	Hs.444356 Hs.708119	438	SH3/SH2 adaptor activity epidermal growth factor receptor binding Golgi apparatus cytosol cytosol epidermal growth factor receptor signaling pathway Ras protein signal transduction Ras protein signal transduction cell-cell signaling insulin receptor signaling pathway insulin receptor substrate binding interspecies interaction between organisms	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
233986_s_at	0.371	4.238	3.053	7.944e-03	0.151	-2.511	PLEKHG2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	19	44595589	AK026111	64857	19q13.2	Hs.631574	4	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
237289_at	-0.310	5.206	-3.053	7.955e-03	0.151	-2.513	CREB1	cAMP responsive element binding protein 1	2	208102860	AW593801	1385	2q34	Hs.516646	215	transcription factor activity transcription cofactor activity nucleus nucleoplasm regulation of transcription, DNA-dependent protein amino acid phosphorylation signal transduction response to organic substance sequence-specific DNA binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter protein dimerization activity	Antigen processing and presentation Melanogenesis Huntington's disease Prostate cancer
217751_at	0.374	9.204	3.053	7.957e-03	0.151	-2.513	GSTK1	glutathione S-transferase kappa 1	7	142670643	NM_015917	373156	7q35	Hs.390667	19	glutathione transferase activity intracellular peroxisome protein disulfide oxidoreductase activity transferase activity outer membrane-bounded periplasmic space identical protein binding	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450
208788_at	0.501	6.150	3.052	7.963e-03	0.151	-2.513	ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)	6	-53240154	AL136939	60481	6p21.1-p12.1	Hs.713560	11	endoplasmic reticulum fatty acid biosynthetic process membrane integral to membrane	Biosynthesis of unsaturated fatty acids
226726_at	0.308	4.980	3.052	7.968e-03	0.151	-2.514	MBOAT2	membrane bound O-acyltransferase domain containing 2	2	-8914151	W63676	129642	2p25.1	Hs.467634 Hs.593538	7	1-acylglycerol-3-phosphate O-acyltransferase activity acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
208981_at	0.467	7.209	3.052	7.969e-03	0.151	-2.514	PECAM1	platelet/endothelial cell adhesion molecule	17	-59753594	AA702701	5175	17q23	Hs.514412 Hs.718947	147	protein binding extracellular space plasma membrane plasma membrane cell adhesion signal transduction cell recognition integral to membrane platelet alpha granule membrane	Cell adhesion molecules (CAMs) Leukocyte transendothelial migration
202417_at	-0.478	8.783	-3.051	7.982e-03	0.151	-2.516	KEAP1	kelch-like ECH-associated protein 1	19	-10457795, -10457795	NM_012289	9817	19p13.2	Hs.465870	51	in utero embryonic development protein binding nucleus nucleolus cytoplasm endoplasmic reticulum centrosome transcription regulator activity regulation of transcription regulation of epidermal cell differentiation	Ubiquitin mediated proteolysis
204789_at	0.280	5.713	3.051	7.984e-03	0.151	-2.516	FMNL1	formin-like 1	17	40655074	NM_005892	752	17q21	Hs.100217	11	molecular_function actin binding cellular_component cytoplasm cellular component organization Rho GTPase binding actin cytoskeleton organization
207808_s_at	0.395	5.468	3.050	7.992e-03	0.151	-2.517	PROS1	protein S (alpha)	3	-95074571	NM_000313	5627	3q11.2	Hs.64016	111	endopeptidase inhibitor activity calcium ion binding extracellular region blood coagulation	Complement and coagulation cascades
225325_at	0.282	6.026	3.050	8.000e-03	0.151	-2.518	MFSD6	major facilitator superfamily domain containing 6	2	190981325	AA133311	54842	2q32.2	Hs.418581 Hs.715029	5	membrane integral to membrane
222136_x_at	0.455	5.307	3.050	8.003e-03	0.151	-2.518	ZNF43	zinc finger protein 43	19	-21779591	AK022905	7594	19p13.1-p12	Hs.534365	13	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
207180_s_at	-0.312	7.429	-3.049	8.012e-03	0.151	-2.519	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	11	20341806, 20341822, 20341864, 20341978, 20342262	NM_006410	10553	11p15.1	Hs.90753	31	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction
235163_at	0.341	6.615	3.049	8.019e-03	0.151	-2.520	MOBKL2A	MOB1, Mps One Binder kinase activator-like 2A (yeast)	19	-2022034	BE311936	126308	19p13.3	Hs.86912	9	protein binding intracellular zinc ion binding metal ion binding
208969_at	0.489	10.334	3.048	8.031e-03	0.151	-2.521	NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	12	4628543	AF050641	4704	12p13.3	Hs.75227	14	catalytic activity NADH dehydrogenase activity NADH dehydrogenase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone transport sodium ion transport NADH dehydrogenase (ubiquinone) activity electron transport chain cellular metabolic process coenzyme binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
211717_at	-0.477	6.045	-3.048	8.035e-03	0.151	-2.522	ANKRD40	ankyrin repeat domain 40	17	-46125550	BC005853	91369	17q21.33	Hs.463426	2
232175_at	0.281	6.270	3.048	8.035e-03	0.151	-2.522	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AI972094	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
226195_at	0.367	6.195	3.048	8.039e-03	0.151	-2.522	C14orf179	chromosome 14 open reading frame 179	14	75521848	AW827281	112752	14q24.3	Hs.532626	5
227899_at	0.405	5.975	3.047	8.043e-03	0.151	-2.523	VIT	vitrin	2	36777417	AI817458	5212	2p22-p21	Hs.137415	7	extracellular region proteinaceous extracellular matrix
34031_i_at	-0.708	6.513	-3.047	8.048e-03	0.151	-2.523	KRIT1	KRIT1, ankyrin repeat containing	7	-91666218, -91666218, -91666218	U90269	889	7q21-q22	Hs.531987	48	small GTPase regulator activity protein binding cytoskeleton small GTPase mediated signal transduction membrane
214274_s_at	0.473	8.188	3.047	8.048e-03	0.151	-2.523	ACAA1	acetyl-Coenzyme A acyltransferase 1	3	-38139204	AI860341	30	3p23-p22	Hs.643487	17	acetyl-CoA C-acyltransferase activity protein binding cytoplasm peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process metabolic process acyltransferase activity transferase activity intracellular membrane-bounded organelle	Fatty acid metabolism Valine, leucine and isoleucine degradation Biosynthesis of unsaturated fatty acids Metabolic pathways PPAR signaling pathway
218304_s_at	-0.506	9.339	-3.046	8.062e-03	0.152	-2.525	OSBPL11	oxysterol binding protein-like 11	3	-126730397	NM_022776	114885	3q21	Hs.477440	12	lipid transport steroid metabolic process
1552536_at	-0.265	3.354	-3.046	8.064e-03	0.152	-2.525	VTI1A	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	10	114196745	NM_145206	143187	10q25.2	Hs.194554	10	SNAP receptor activity intracellular protein transport protein transporter activity membrane vesicle-mediated transport SNARE complex retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
1559079_at	0.238	3.359	3.046	8.069e-03	0.152	-2.526	LOC283486	hypothetical protein LOC283486	13		BC035264	283486	13q34	Hs.447504	1
221559_s_at	-0.488	7.202	-3.046	8.070e-03	0.152	-2.526	MIS12	MIS12, MIND kinetochore complex component, homolog (S. pombe)	17	5330970	BC000229	79003	17p13.2	Hs.267194	11	MIS12/MIND type complex chromosome, centromeric region protein binding nucleus cell cycle chromosome segregation mitosis cell division kinetochore assembly
225153_at	-0.294	9.852	-3.045	8.078e-03	0.152	-2.527	GFM1	G elongation factor, mitochondrial 1	3	159845010	AI814295	85476	3q25.1-q26.2	Hs.518355	11	nucleotide binding translation elongation factor activity GTPase activity GTP binding intracellular mitochondrion translational elongation
227463_at	0.406	5.434	3.045	8.086e-03	0.152	-2.528	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	17	58908165, 58915908	AW057540	1636	17q23.3	Hs.654434	1473	kidney development angiotensin catabolic process in blood regulation of systemic arterial blood pressure by renin-angiotensin carboxypeptidase activity extracellular region extracellular space membrane fraction endosome plasma membrane proteolysis drug binding regulation of blood pressure peptidase activity metallopeptidase activity metallopeptidase activity peptidyl-dipeptidase activity peptidyl-dipeptidase activity zinc ion binding external side of plasma membrane regulation of smooth muscle cell migration integral to membrane regulation of vasoconstriction chloride ion binding bradykinin receptor binding mononuclear cell proliferation regulation of vasodilation hormone catabolic process hormone catabolic process peptide catabolic process metal ion binding arachidonic acid secretion hemopoietic stem cell differentiation	Renin-angiotensin system Hypertrophic cardiomyopathy (HCM)
214987_at	-0.271	5.482	-3.045	8.087e-03	0.152	-2.528	GAB1	GRB2-associated binding protein 1	4	144477432	AL049449	2549	4q31.21	Hs.618456 Hs.80720	69	SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway	ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma
215177_s_at	0.521	6.121	3.044	8.090e-03	0.152	-2.528	ITGA6	integrin, alpha 6	2	173000559	AV733308	3655	2q31.1	Hs.133397	114	receptor activity calcium ion binding protein binding cell-substrate junction assembly cell adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Hematopoietic cell lineage Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
203088_at	0.389	5.925	3.044	8.094e-03	0.152	-2.528	FBLN5	fibulin 5	14	-91405507	NM_006329	10516	14q32.1	Hs.332708	38	integrin binding calcium ion binding protein binding extracellular region proteinaceous extracellular matrix soluble fraction cell adhesion cell-matrix adhesion
200045_at	-0.378	8.182	-3.044	8.094e-03	0.152	-2.528	ABCF1	ATP-binding cassette, sub-family F (GCN20), member 1	6	30647148, 1987727, 1786022	NM_001090	23	6p21.33	Hs.655285	15	nucleotide binding ATP binding translation inflammatory response translation factor activity, nucleic acid binding ATPase activity ATPase activity, coupled to transmembrane movement of substances
202165_at	-0.820	7.556	-3.044	8.104e-03	0.152	-2.530	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	3	-196722511	BF966540	5504	3q29	Hs.535731 Hs.706920	22	protein serine/threonine phosphatase inhibitor activity protein binding carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy regulation of signal transduction regulation of phosphoprotein phosphatase activity
226627_at	0.348	5.483	3.043	8.117e-03	0.152	-2.531	SEPT8	septin 8	5	-132119595, -132119595, -132114407	AI912094	23176	5q31	Hs.522057	17	nucleotide binding protein binding GTP binding cell cycle septin complex
221213_s_at	-0.616	6.533	-3.041	8.143e-03	0.152	-2.534	ZNF280D	zinc finger protein 280D	15	-54778849, -54709665	NM_017661	54816	15q21.3	Hs.511477	8	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1557950_at	-0.404	6.619	-3.041	8.145e-03	0.152	-2.534	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	BF984340	9147	14q22	Hs.655964	8	nucleus cytoplasm
221350_at	0.278	5.133	3.041	8.152e-03	0.152	-2.535	HOXC8	homeobox C8	12	52689156	NM_022658	3224	12q13.3	Hs.664500	25	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation transcription repressor activity neuron differentiation sequence-specific DNA binding skeletal system morphogenesis
201258_at	-0.454	11.844	-3.041	8.152e-03	0.152	-2.535	RPS16	ribosomal protein S16	19	-44615686	NM_001020	6217	19q13.1	Hs.397609	24	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
204616_at	0.577	9.304	3.041	8.154e-03	0.152	-2.535	UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	13	75021927	NM_006002	7347	13q22.2	Hs.162241	17	ubiquitin thiolesterase activity intracellular cytoplasm ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
209083_at	0.311	5.443	3.041	8.156e-03	0.152	-2.535	CORO1A	coronin, actin binding protein, 1A	16	30102426	U34690	11151	16p11.2	Hs.415067	23	immunological synapse phagolysosome formation phagocytic cup nucleus cytoplasm plasma membrane cell cortex calcium ion transport cell motion actin filament organization protein C-terminus binding regulation of cell shape lamellipodium positive regulation of cell migration leukocyte chemotaxis phagocytic vesicle membrane regulation of actin filament polymerization cortical actin cytoskeleton cytoplasmic vesicle cell-substrate adhesion filamentous actin uropod organization response to cytokine stimulus positive regulation of T cell proliferation protein homodimerization activity T cell homeostasis phosphoinositide 3-kinase binding innate immune response homeostasis of number of cells within a tissue positive chemotaxis actin filament binding negative regulation of actin nucleation
213915_at	0.540	4.501	3.040	8.171e-03	0.152	-2.537	NKG7	natural killer cell group 7 sequence	19	-56566685	NM_005601	4818	19q13.41	Hs.10306	4	integral to plasma membrane membrane
219368_at	0.680	4.447	3.039	8.178e-03	0.152	-2.538	NAP1L2	nucleosome assembly protein 1-like 2	X	-72348878	NM_021963	4674	Xq13	Hs.66180 Hs.719281	4	nucleus chromatin assembly complex nucleosome assembly
222442_s_at	-0.406	7.601	-3.039	8.178e-03	0.152	-2.538	ARL8B	ADP-ribosylation factor-like 8B	3	5138929	AW055237	55207	3p26.1	Hs.250009 Hs.719100	10	nucleotide binding GTPase activity GTP binding intracellular cytoplasm lysosomal membrane endosome chromosome segregation small GTPase mediated signal transduction membrane GDP binding midbody late endosome membrane alpha-tubulin binding beta-tubulin binding spindle midzone
239772_x_at	0.290	6.303	3.039	8.182e-03	0.152	-2.538	DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	3	47819402	AI368527	22907	3p21.31	Hs.517948	7	nucleotide binding RNA binding helicase activity ATP binding cytoplasm mitochondrion ATP-dependent helicase activity hydrolase activity mitochondrial nucleoid
224865_at	-0.278	6.929	-3.039	8.185e-03	0.152	-2.539	FAR1	fatty acyl CoA reductase 1	11	13646781	N63551	84188	11p15.2	Hs.501991	10	protein binding peroxisome lipid biosynthetic process membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor oxidation reduction
225484_at	0.324	4.076	3.038	8.191e-03	0.152	-2.539	TSGA14	testis specific, 14	7	-129823610	AW157525	95681	7q32	Hs.368315	6	centrosome
222407_s_at	-0.552	10.913	-3.038	8.195e-03	0.152	-2.540	ZFP106	zinc finger protein 106 homolog (mouse)	15	-40492312	AI493587	64397	15q15.1	Hs.511143	9	opioid peptide activity intracellular membrane fraction nucleus nucleolus cytosol zinc ion binding insulin receptor signaling pathway SH3 domain binding metal ion binding
225191_at	0.375	7.279	3.038	8.198e-03	0.152	-2.540	CIRBP	cold inducible RNA binding protein	19	1220266, 1220266	AL565767	1153	19p13.3	Hs.634522 Hs.664127	17	nucleotide binding RNA binding protein binding nucleus nucleoplasm response to cold
224664_at	-0.275	10.834	-3.038	8.199e-03	0.152	-2.540	C10orf104	chromosome 10 open reading frame 104	10	73645811	BE962336	119504	10q22.1	Hs.426296	5
201733_at	-0.571	3.731	-3.038	8.199e-03	0.152	-2.540	CLCN3	chloride channel 3	4	170778296	AA902971	1182	4q33	Hs.481186	28	nucleotide binding ion channel activity voltage-gated chloride channel activity protein binding ATP binding early endosome early endosome late endosome late endosome Golgi apparatus Golgi apparatus ion transport chloride transport regulation of pH cell surface vesicle membrane vesicle membrane antiporter activity membrane integral to membrane PDZ domain binding PDZ domain binding chloride ion binding cytoplasmic vesicle protein homodimerization activity protein heterodimerization activity protein heterodimerization activity endosomal lumen acidification
202661_at	0.276	3.582	3.038	8.200e-03	0.152	-2.540	ITPR2	inositol 1,4,5-triphosphate receptor, type 2	12	-26379551	AI963873	3709	12p11	Hs.512235	22	response to hypoxia plasma membrane enriched fraction ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding cytoplasm microsome cell cortex ion transport calcium ion transport signal transduction calcium ion transmembrane transporter activity membrane integral to membrane sarcoplasmic reticulum membrane phosphoinositide binding	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease
227551_at	-0.498	7.428	-3.038	8.202e-03	0.152	-2.541	FAM108B1	family with sequence similarity 108, member B1	9	-73669887, -73667187	BE856596	51104	9q21.13	Hs.380389	4	extracellular region hydrolase activity
1555759_a_at	0.328	5.788	3.038	8.206e-03	0.152	-2.541	CCL5	chemokine (C-C motif) ligand 5	17	-31222608	AF043341	6352	17q11.2-q12	Hs.514821	312	signal transducer activity extracellular region extracellular space cytoplasm cellular calcium ion homeostasis exocytosis cell motion chemotaxis inflammatory response immune response cellular defense response response to oxidative stress cell adhesion signal transduction cell-cell signaling chemokine activity response to virus response to tumor necrosis factor chemoattractant activity negative regulation of viral genome replication	Cytokine-cytokine receptor interaction Chemokine signaling pathway Toll-like receptor signaling pathway Prion diseases Epithelial cell signaling in Helicobacter pylori infection
202381_at	-0.388	7.704	-3.037	8.210e-03	0.152	-2.542	ADAM9	ADAM metallopeptidase domain 9 (meltrin gamma)	8	38973661, 38973661	NM_003816	8754	8p11.22	Hs.591852	36	activation of MAPKK activity metalloendopeptidase activity protein kinase C binding integrin binding integrin binding integrin binding collagen binding extracellular region extracellular space cytoplasm plasma membrane proteolysis response to oxidative stress cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway peptidase activity zinc ion binding cell surface response to manganese ion integral to membrane SH3 domain binding SH3 domain binding keratinocyte differentiation intrinsic to external side of plasma membrane positive regulation of cell adhesion mediated by integrin cell-cell adhesion mediated by integrin positive regulation of macrophage fusion response to tumor necrosis factor monocyte activation response to hydrogen peroxide laminin binding metal ion binding positive regulation of protein secretion positive regulation of membrane protein ectodomain proteolysis PMA-inducible membrane protein ectodomain proteolysis response to glucocorticoid stimulus positive regulation of keratinocyte migration response to calcium ion
209187_at	-0.417	8.295	-3.037	8.211e-03	0.152	-2.542	DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	1	93584065	AW516932	1810	1p22.1	Hs.348418	23	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity intracellular nucleus transcription factor binding sequence-specific DNA binding regulation of transcription
219821_s_at	-0.386	7.453	-3.037	8.220e-03	0.152	-2.543	GFOD1	glucose-fructose oxidoreductase domain containing 1	6	-13471797	NM_018988	54438	6pter-p22.1	Hs.484686	5	binding extracellular region electron carrier activity oxidoreductase activity oxidation reduction
201941_at	0.321	6.954	3.037	8.221e-03	0.152	-2.543	CPD	carboxypeptidase D	17	25730109	BE349147	1362	17q11.2	Hs.446079	16	metallocarboxypeptidase activity serine-type carboxypeptidase activity membrane fraction nucleus proteolysis peptidase activity metallopeptidase activity zinc ion binding membrane integral to membrane metal ion binding
201151_s_at	-0.860	7.994	-3.036	8.225e-03	0.152	-2.543	MBNL1	muscleblind-like (Drosophila)	3	153468518, 153499883	BF512200	4154	3q25	Hs.478000 Hs.558914	21	in utero embryonic development double-stranded RNA binding nucleus cytoplasm nervous system development muscle organ development zinc ion binding embryonic limb morphogenesis myoblast differentiation metal ion binding
220637_at	0.307	3.950	3.036	8.229e-03	0.152	-2.544	FAM124B	family with sequence similarity 124B	2	-224951658	NM_024785	79843	2q36.2	Hs.147585	3	protein binding
216082_at	0.304	4.629	3.036	8.234e-03	0.152	-2.544	NEU3	sialidase 3 (membrane sialidase)	11	74377597	AK022450	10825	11q13.5	Hs.191074	25	exo-alpha-sialidase activity plasma membrane integral to plasma membrane carbohydrate metabolic process ganglioside catabolic process metabolic process hydrolase activity, acting on glycosyl bonds	Other glycan degradation Sphingolipid metabolism
241869_at	0.321	4.724	3.035	8.247e-03	0.153	-2.546	APOL6	apolipoprotein L, 6	22	34374369	AW026509	80830	22q12.3	Hs.257352	12	lipid transporter activity extracellular region cytoplasm lipid transport lipid binding lipoprotein metabolic process
1556300_s_at	-1.421	6.008	-3.035	8.255e-03	0.153	-2.546	SIM1	single-minded homolog 1 (Drosophila)	6	-100943470	BF476109	6492	6q16.3-q21	Hs.520293	17	transcription factor activity signal transducer activity protein binding nucleus Golgi apparatus regulation of transcription, DNA-dependent signal transduction multicellular organismal development nervous system development cell differentiation protein heterodimerization activity
228029_at	-0.351	5.875	-3.034	8.259e-03	0.153	-2.547	ZNF721	zinc finger protein 721	4	-423778	AW513477	170960	4p16.3	Hs.428360	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
218401_s_at	-0.561	6.409	-3.034	8.269e-03	0.153	-2.548	ZNF281	zinc finger protein 281	1	-198642042	NM_012482	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
210164_at	0.410	4.117	3.033	8.276e-03	0.153	-2.549	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	14	-24170003	J03189	3002	14q11.2	Hs.1051	142	immunological synapse serine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis apoptosis cleavage of lamin peptidase activity cytolysis	Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
201440_at	-0.319	6.812	-3.033	8.278e-03	0.153	-2.549	DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	12	-47509805	NM_004818	9416	12q13.12	Hs.130098	13	nucleotide binding cis assembly of pre-catalytic spliceosome nuclear mRNA splicing, via spliceosome nucleic acid binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus spliceosomal complex U5 snRNP RNA splicing hydrolase activity RNA splicing factor activity, transesterification mechanism
208405_s_at	-0.400	8.931	-3.033	8.281e-03	0.153	-2.549	CD164	CD164 molecule, sialomucin	6	-109794411	NM_006016	8763	6q21	Hs.520313 Hs.644693	17	extracellular region plasma membrane integral to plasma membrane immune response cell adhesion heterophilic cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation	Lysosome
210033_s_at	0.327	3.035	3.033	8.285e-03	0.153	-2.550	SPAG6	sperm associated antigen 6	10	22674404	AF079363	9576	10p12.2	Hs.655170	14	binding cytoplasm microtubule cilium axoneme spermatid development flagellum cell projection organization
225875_s_at	0.567	5.897	3.033	8.286e-03	0.153	-2.550	NIPAL3	NIPA-like domain containing 3	1	24614831	T84558	57185	1p36.12-p35.1	Hs.523442	6	membrane integral to membrane
220392_at	0.369	4.711	3.033	8.290e-03	0.153	-2.550	EBF2	early B-cell factor 2	8	-25757489	NM_022659	64641	8p21.2	Hs.710674	8	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity positive regulation of transcription metal ion binding
1554661_s_at	-0.386	4.772	-3.032	8.293e-03	0.153	-2.551	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	BC036200	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
217148_x_at	0.569	5.646	3.032	8.294e-03	0.153	-2.551	IGL@	immunoglobulin lambda locus	22		AJ249377	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
204118_at	0.389	4.535	3.031	8.310e-03	0.153	-2.553	CD48	CD48 molecule	1	-158915159	NM_001778	962	1q21.3-q22	Hs.243564	35	protein binding plasma membrane integral to plasma membrane defense response anchored to membrane membrane raft	Natural killer cell mediated cytotoxicity
219402_s_at	-0.558	7.489	-3.031	8.312e-03	0.153	-2.553	DERL1	Der1-like domain family, member 1	8	-124094748	NM_024295	79139	8q24.13	Hs.241576	28	receptor activity protein binding endoplasmic reticulum endoplasmic reticulum response to unfolded protein protein transport membrane integral to membrane intracellular transport of viral proteins in host cell integral to endoplasmic reticulum membrane ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol MHC class I protein binding interspecies interaction between organisms	Amyotrophic lateral sclerosis (ALS)
228339_at	0.385	7.373	3.031	8.316e-03	0.153	-2.553	ECSCR	endothelial cell-specific chemotaxis regulator	5	-138812143	AA181256	641700	5q31.2	Hs.483538 Hs.570903	5	angiogenesis plasma membrane chemotaxis multicellular organismal development integral to membrane cell differentiation
238320_at	-0.333	5.661	-3.031	8.320e-03	0.153	-2.554	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AV659198	283131	11q13.1	Hs.523789 Hs.648467	6
1558281_a_at	0.356	4.278	3.031	8.321e-03	0.153	-2.554	TMEM184A	transmembrane protein 184A	7	-1548396	BQ277407	202915	7p22.3	Hs.592174 Hs.707784	5	membrane integral to membrane
1552889_a_at	0.320	7.034	3.031	8.324e-03	0.153	-2.554	EXOC3L2	exocyst complex component 3-like 2	19	-50407718	NM_138568	90332	19q13.32	Hs.337557	5
201529_s_at	-0.460	7.072	-3.030	8.337e-03	0.153	-2.556	RPA1	replication protein A1, 70kDa	17	1680022	NM_002945	6117	17p13.3	Hs.461925 Hs.595562	106	nucleotide-excision repair, DNA damage removal double-strand break repair via homologous recombination condensed nuclear chromosome male germ cell nucleus in utero embryonic development DNA binding chromatin binding single-stranded DNA binding protein binding nucleus nucleoplasm DNA replication factor A complex cytoplasm cytoskeleton DNA-dependent DNA replication DNA repair nucleotide-excision repair, DNA gap filling DNA recombination meiosis zinc ion binding positive regulation of cell proliferation PML body hemopoiesis metal ion binding homeostasis of number of cells within a tissue chromosome organization	DNA replication Nucleotide excision repair Mismatch repair Homologous recombination
1553186_x_at	-0.518	8.728	-3.030	8.338e-03	0.153	-2.556	RASEF	RAS and EF-hand domain containing	9	-84787136	NM_152573	158158	9q21.32	Hs.657750	3	nucleotide binding calcium ion binding GTP binding cytoplasm small GTPase mediated signal transduction protein transport perinuclear region of cytoplasm
212505_s_at	-0.341	7.764	-3.030	8.339e-03	0.153	-2.556	KIAA0892	KIAA0892	19	19292629	AL110250	23383	19p13.11	Hs.654939 Hs.713004	8	chromatin protein binding extracellular region nucleus nucleoplasm cohesin loading complex maintenance of mitotic sister chromatid cohesion
243452_at	0.424	3.711	3.030	8.341e-03	0.153	-2.556	LOC646778	hypothetical LOC646778	18		BE895304	646778	18q12.1	Hs.631680	1
225315_at	0.385	8.929	3.029	8.345e-03	0.153	-2.556	MRPL21	mitochondrial ribosomal protein L21	11	-68415321	BF344406	219927	11q13.3	Hs.503047	6	RNA binding structural constituent of ribosome intracellular mitochondrion ribosome translation
1554637_a_at	0.257	5.437	3.028	8.370e-03	0.153	-2.559	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	20	31541588, 31613831	BC015066	9139	20q11	Hs.153934	19	transcription factor activity transcription corepressor activity protein binding nucleus zinc ion binding epithelial cell differentiation negative regulation of transcription, DNA-dependent metal ion binding
223092_at	-0.486	10.131	-3.027	8.377e-03	0.154	-2.560	ANKH	ankylosis, progressive homolog (mouse)	5	-14757908	AA854943	56172	5p15.1	Hs.156727	36	skeletal system development inorganic phosphate transmembrane transporter activity integral to plasma membrane transport phosphate transport locomotory behavior outer membrane outer membrane regulation of bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity
203077_s_at	-0.512	6.729	-3.027	8.387e-03	0.154	-2.561	SMAD2	SMAD family member 2	18	-43613464, -43613463, -43613463	NM_005901	4087	18q21.1	Hs.12253 Hs.705764	206	mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol	Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer
201518_at	-0.387	8.556	-3.026	8.396e-03	0.154	-2.562	CBX1	chromobox homolog 1 (HP1 beta homolog Drosophila )	17	-43502412, -43502412	NM_006807	10951	17q21.32	Hs.77254	44	chromosome, centromeric region chromatin chromatin binding nucleus nucleoplasm nuclear heterochromatin spindle chromatin assembly or disassembly enzyme binding
202233_s_at	0.312	11.913	3.026	8.399e-03	0.154	-2.562	UQCRH	ubiquinol-cytochrome c reductase hinge protein	1	46541966	NM_006004	7388	1p34.1	Hs.481571	9	mitochondrion mitochondrial respiratory chain oxidative phosphorylation mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity aerobic respiration membrane electron transport chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
1559746_a_at	0.338	4.826	3.026	8.402e-03	0.154	-2.563	ZNF718	zinc finger protein 718	4	43276	AK096662	255403	4p16.3	Hs.428579 Hs.636638	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
226430_at	0.565	8.163	3.026	8.407e-03	0.154	-2.563	RELL1	RELT-like 1	4	-37288650, -37268816	AI394438	768211	4p14	Hs.283378 Hs.708605	4	plasma membrane integral to membrane
209712_at	-0.475	6.465	-3.026	8.409e-03	0.154	-2.564	SLC35D1	solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1	1	-67237603	AI769637	23169	1p32-p31	Hs.213642	8	UDP-N-acetylgalactosamine transmembrane transporter activity endoplasmic reticulum carbohydrate transport UDP-N-acetylgalactosamine transport membrane integral to membrane integral to endoplasmic reticulum membrane chondroitin sulfate biosynthetic process
208454_s_at	0.256	6.233	3.025	8.421e-03	0.154	-2.565	PGCP	plasma glutamate carboxypeptidase	8	97726674	NM_016134	10404	8q22.2	Hs.156178	4	metallocarboxypeptidase activity extracellular region extracellular space cytoplasm proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding metal ion binding
229073_at	0.351	3.389	3.025	8.423e-03	0.154	-2.565	PRTG	protogenin homolog (Gallus gallus)	15	-53691041	AA912476	283659	15q21.3	Hs.130957	4	multicellular organismal development membrane integral to membrane
204134_at	0.447	6.596	3.025	8.425e-03	0.154	-2.565	PDE2A	phosphodiesterase 2A, cGMP-stimulated	11	-71964833, -71964833, -71964833, -71964833	NM_002599	5138	11q13.4	Hs.503163	11	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity protein binding signal transduction membrane hydrolase activity	Purine metabolism
219523_s_at	0.289	4.537	3.024	8.428e-03	0.154	-2.566	ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)	4	183482130	NM_018104	55714	4q35.1	Hs.130438	7	signal transduction membrane integral to membrane
208653_s_at	-0.533	4.221	-3.024	8.429e-03	0.154	-2.566	CD164	CD164 molecule, sialomucin	6	-109794411	AF263279	8763	6q21	Hs.520313 Hs.644693	17	extracellular region plasma membrane integral to plasma membrane immune response cell adhesion heterophilic cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation	Lysosome
205551_at	0.490	5.273	3.024	8.438e-03	0.154	-2.567	SV2B	synaptic vesicle glycoprotein 2B	15	89570106	NM_014848	9899	15q26.1	Hs.21754	12	acrosomal vesicle transporter activity protein binding neurotransmitter transport synaptic vesicle membrane integral to membrane cell junction cytoplasmic vesicle synapse regulation of protein metabolic process	ECM-receptor interaction
231913_s_at	-0.377	5.710	-3.024	8.442e-03	0.154	-2.567	BRCC3	BRCA1/BRCA2-containing complex, subunit 3	X	153952903	X64643	79184	Xq28	Hs.558537	19	nuclear ubiquitin ligase complex ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding nucleus double-strand break repair response to DNA damage stimulus peptidase activity metallopeptidase activity zinc ion binding response to X-ray chromatin modification modification-dependent protein catabolic process enzyme regulator activity G2/M transition DNA damage checkpoint polyubiquitin binding positive regulation of DNA repair metal ion binding BRCA1-A complex histone H2A K63-linked deubiquitination histone H2A K63-linked deubiquitination BRISC complex
214118_x_at	-0.281	8.593	-3.023	8.453e-03	0.154	-2.568	PCM1	pericentriolar material 1	8	17824645	AI205598	5108	8p22-p21.3	Hs.491148	36	pericentriolar material protein binding cytoplasm cytoskeleton nonmotile primary cilium centriolar satellite cilium assembly cilium assembly centrosome organization
209316_s_at	-0.433	8.606	-3.023	8.460e-03	0.154	-2.569	HBS1L	HBS1-like (S. cerevisiae)	6	-135398687, -135323215, -135323213	BC001465	10767	6q23-q24	Hs.378532	12	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation signal transduction
202521_at	-0.517	7.560	-3.023	8.460e-03	0.154	-2.569	CTCF	CCCTC-binding factor (zinc finger protein)	16	66153964	NM_006565	10664	16q21-q22.3	Hs.368367	79	chromosome, centromeric region condensed chromosome transcription factor activity transcription corepressor activity protein binding intracellular nucleus nucleoplasm nucleolus DNA methylation genetic imprinting zinc ion binding maintenance of DNA methylation positive regulation of gene expression promoter binding transcription activator activity nucleosome positioning regulation of molecular function, epigenetic chromatin insulator sequence binding negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding regulation of centromeric sister chromatid cohesion
212311_at	0.364	4.444	3.022	8.463e-03	0.154	-2.569	KIAA0746	KIAA0746 protein	4	-25358146	AA522514	23231	4p15.2	Hs.479384	5	binding membrane integral to membrane
225849_s_at	-0.286	7.591	-3.022	8.472e-03	0.154	-2.570	SFT2D1	SFT2 domain containing 1	6	-166653505	BF975327	113402	6q27	Hs.487143	3	protein transport membrane integral to membrane
206710_s_at	0.973	4.228	3.022	8.480e-03	0.154	-2.571	EPB41L3	erythrocyte membrane protein band 4.1-like 3	18	-5382387	NM_012307	23136	18p11.32	Hs.213394	39	actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization	Tight junction
222426_at	-0.236	6.176	-3.021	8.481e-03	0.154	-2.571	MAPKAP1	mitogen-activated protein kinase associated protein 1	9	-127323569, -127239493	BG499947	79109	9q33.3	Hs.495138	19	cellular_component nucleus cytosol plasma membrane biological_process Ras GTPase binding cytoplasmic vesicle
226106_at	-0.445	8.884	-3.021	8.485e-03	0.154	-2.572	RNF141	ring finger protein 141	11	-10489800	AI307808	50862	11p15.4	Hs.44685	7	DNA binding protein binding regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212235_at	0.323	6.490	3.021	8.494e-03	0.154	-2.573	PLXND1	plexin D1	3	-130756745	AL575403	23129	3q22.1	Hs.301685	10	receptor activity intracellular plasma membrane signal transduction multicellular organismal development integral to membrane
210847_x_at	0.352	3.575	3.021	8.495e-03	0.154	-2.573	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	1	-6446757, -6443800	AF026071	8718	1p36.2	Hs.462529	30	receptor activity tumor necrosis factor receptor activity protein binding extracellular region cytosol plasma membrane integral to plasma membrane cell surface receptor linked signal transduction induction of apoptosis by extracellular signals regulation of apoptosis	Cytokine-cytokine receptor interaction
215546_at	0.359	4.404	3.020	8.501e-03	0.154	-2.573	PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	9	-122618152	AK001065	5711	9q33.2	Hs.193725	39	proteasome complex binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
221486_at	-0.490	9.846	-3.020	8.504e-03	0.154	-2.574	ENSA	endosulfine alpha	1	-148866145, -148862377, -148862377, -148861222, -148861222	AF067170	2029	1q21.3	Hs.632456	15	receptor binding cytoplasm transport response to nutrient ion channel inhibitor activity
201828_x_at	0.446	9.276	3.020	8.508e-03	0.154	-2.574	FAM127A	family with sequence similarity 127, member A	X	133993998	NM_003928	8933	Xq26	Hs.522789	9
200990_at	-0.278	7.023	-3.020	8.512e-03	0.154	-2.575	TRIM28	tripartite motif-containing 28	19	63747647	NM_005762	10155	19q13.4	Hs.467408	54	epithelial to mesenchymal transition transcription factor activity transcription corepressor activity protein binding intracellular nucleus regulation of transcription from RNA polymerase II promoter zinc ion binding positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription metal ion binding
235958_at	0.297	6.224	3.019	8.519e-03	0.154	-2.575	PLA2G4F	phospholipase A2, group IVF	15	-40220688	AW299828	255189	15q15.1	Hs.231873	6	phospholipase A2 activity calcium ion binding cytoplasm lysosome cytosol metabolic process phospholipid catabolic process membrane lipid catabolic process hydrolase activity	Fc gamma R-mediated phagocytosis
242271_at	1.945	6.742	3.019	8.519e-03	0.154	-2.575	SLC26A9	solute carrier family 26, member 9	1	-204148801, -204148801	AI932662	115019	1q31-q32	Hs.164073	8	transporter activity transport chloride transport regulation of pH secondary active sulfate transmembrane transporter activity sulfate transport bicarbonate transmembrane transporter activity anion:anion antiporter activity bicarbonate transport membrane integral to membrane apical plasma membrane
229331_at	0.348	2.702	3.019	8.525e-03	0.154	-2.576	SPATA18	spermatogenesis associated 18 homolog (rat)	4	52612349	AI559300	132671	4q12	Hs.527090	4	cytoplasm multicellular organismal development spermatogenesis cell differentiation
215501_s_at	-0.673	6.548	-3.019	8.527e-03	0.154	-2.576	DUSP10	dual specificity phosphatase 10	1	-219941388, -219941388	AK022513	11221	1q41	Hs.497822	15	protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation response to stress JNK cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity	MAPK signaling pathway
203203_s_at	-0.420	6.792	-3.019	8.527e-03	0.154	-2.576	KRR1	KRR1, small subunit (SSU) processome component, homolog (yeast)	12	-74177685	NM_007043	11103	12q21.2	Hs.645517	16	RNA binding nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing
201792_at	0.241	5.774	3.018	8.533e-03	0.154	-2.577	AEBP1	AE binding protein 1	7	44110484	NM_001129	165	7p13	Hs.439463	9	skeletal system development transcription factor activity metallocarboxypeptidase activity extracellular region nucleus cytoplasm proteolysis cell adhesion muscle organ development zinc ion binding regulation of transcription
210346_s_at	-0.574	7.606	-3.017	8.557e-03	0.155	-2.579	CLK4	CDC-like kinase 4	5	-177962270	AF212224	57396	5q35	Hs.406557	7	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus transferase activity peptidyl-tyrosine phosphorylation protein amino acid autophosphorylation
202587_s_at	-0.603	10.851	-3.016	8.583e-03	0.155	-2.582	AK1	adenylate kinase 1	9	-129668579	BC001116	203	9q34.1	Hs.175473	24	nucleotide binding adenylate kinase activity protein binding ATP binding nucleus cytoplasm mitochondrion cytosol plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle arrest transferase activity nucleoside kinase activity ATP metabolic process	Purine metabolism Metabolic pathways
201735_s_at	-0.519	6.971	-3.015	8.588e-03	0.155	-2.583	CLCN3	chloride channel 3	4	170778296	NM_001829	1182	4q33	Hs.481186	28	nucleotide binding ion channel activity voltage-gated chloride channel activity protein binding ATP binding early endosome early endosome late endosome late endosome Golgi apparatus Golgi apparatus ion transport chloride transport regulation of pH cell surface vesicle membrane vesicle membrane antiporter activity membrane integral to membrane PDZ domain binding PDZ domain binding chloride ion binding cytoplasmic vesicle protein homodimerization activity protein heterodimerization activity protein heterodimerization activity endosomal lumen acidification
235408_x_at	0.576	3.536	3.015	8.594e-03	0.155	-2.583	ZNF117	zinc finger protein 117	7	-64072264	AW058673	51351	7q11.21	Hs.250693	5	molecular_function transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding metal ion binding
217867_x_at	0.275	6.060	3.015	8.597e-03	0.155	-2.584	BACE2	beta-site APP-cleaving enzyme 2	21	41461597	NM_012105	25825	21q22.3	Hs.529408	42	aspartic-type endopeptidase activity membrane fraction protein modification process proteolysis membrane protein ectodomain proteolysis peptidase activity protein secretion membrane integral to membrane peptide hormone processing negative regulation of amyloid precursor protein biosynthetic process	Alzheimer's disease
203854_at	0.437	4.755	3.015	8.601e-03	0.155	-2.584	CFI	complement factor I	4	-110881296	NM_000204	3426	4q25	Hs.312485	44	serine-type endopeptidase activity scavenger receptor activity extracellular region extracellular space proteolysis complement activation, classical pathway peptidase activity membrane innate immune response	Complement and coagulation cascades
222058_at	0.227	4.403	3.014	8.612e-03	0.155	-2.585	RNF130	ring finger protein 130	5	-179315079	AW194818	55819	5q35.3	Hs.484363	7	molecular_function protein binding apoptosis zinc ion binding membrane integral to membrane metal ion binding
208812_x_at	0.574	10.189	3.013	8.629e-03	0.156	-2.587	HLA-C	major histocompatibility complex, class I, C	6	-31344507, -2686290, -2483726	BC004489	3107	6p21.3	Hs.654404 Hs.656020 Hs.77961	521	antigen processing and presentation of peptide antigen via MHC class I extracellular region plasma membrane integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
207164_s_at	-0.456	3.944	-3.013	8.634e-03	0.156	-2.588	ZNF238	zinc finger protein 238	1	242281183, 242283204	NM_006352	10472	1q44-qter	Hs.69997	11	negative regulation of transcription from RNA polymerase II promoter nuclear chromosome transcription factor activity protein binding intracellular nucleus transport zinc ion binding regulation of transcription metal ion binding
215543_s_at	-0.537	7.717	-3.012	8.645e-03	0.156	-2.589	LARGE	like-glycosyltransferase	22	-31999061	AB011181	9215	22q12.3	Hs.474667	18	Golgi apparatus N-acetylglucosamine metabolic process protein amino acid glycosylation glycosphingolipid biosynthetic process acetylglucosaminyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane muscle maintenance
203338_at	-0.634	8.562	-3.012	8.648e-03	0.156	-2.589	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	14	-62911107	NM_006246	5529	14q23.1	Hs.334868	20	protein phosphatase type 2A complex protein binding cytoplasm signal transduction protein phosphatase type 2A regulator activity intracellular membrane-bounded organelle	Wnt signaling pathway
233813_at	0.513	4.567	3.012	8.648e-03	0.156	-2.589	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B	20	36867761	AK026900	26051	20q11.23	Hs.45719	7	plasma membrane signal transduction protein phosphatase binding
231866_at	-0.486	7.479	-3.012	8.651e-03	0.156	-2.589	LNPEP	leucyl/cystinyl aminopeptidase	5	96297101, 96319911	AA767440	4012	5q15	Hs.527199 Hs.656905	44	aminopeptidase activity extracellular region intracellular plasma membrane integral to plasma membrane proteolysis cell-cell signaling female pregnancy peptidase activity metallopeptidase activity zinc ion binding metal ion binding	Renin-angiotensin system
224636_at	-0.421	8.964	-3.012	8.653e-03	0.156	-2.590	ZFP91	zinc finger protein 91 homolog (mouse)	11	58103162	AL045405	80829	11q12	Hs.524920	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
221503_s_at	-0.770	9.038	-3.011	8.656e-03	0.156	-2.590	KPNA3	karyopherin alpha 3 (importin alpha 4)	13	-49171444	AF034756	3839	13q14.3	Hs.527919	61	protein binding nucleus nuclear pore cytoplasm protein complex assembly NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity
207614_s_at	-0.409	7.395	-3.011	8.656e-03	0.156	-2.590	CUL1	cullin 1	7	148026865	NM_003592	8454	7q36.1	Hs.146806	72	G1/S transition of mitotic cell cycle protein binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process apoptosis cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals organ morphogenesis SCF ubiquitin ligase complex ubiquitin protein ligase binding positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis Wnt signaling pathway TGF-beta signaling pathway
236909_at	0.307	3.093	3.011	8.661e-03	0.156	-2.591	C2orf77	chromosome 2 open reading frame 77	2	-170210180	AW339899	129881	2q31.1	Hs.370111	2
209028_s_at	-0.400	6.373	-3.011	8.661e-03	0.156	-2.591	ABI1	abl-interactor 1	10	-27075530	AF006516	10006	10p11.2	Hs.508148	39	intracellular soluble fraction nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal protein binding negative regulation of cell proliferation peptidyl-tyrosine phosphorylation synaptosome lamellipodium cell junction filopodium growth cone synapse
200958_s_at	-0.310	9.015	-3.011	8.666e-03	0.156	-2.591	SDCBP	syndecan binding protein (syntenin)	8	59628281	NM_005625	6386	8q12	Hs.200804	39	interleukin-5 receptor binding nucleus cytoplasm endoplasmic reticulum cytosol cytoskeleton plasma membrane interleukin-5 receptor complex adherens junction focal adhesion protein targeting to membrane substrate-bound cell migration, cell extension intracellular signaling cascade Ras protein signal transduction synaptic transmission cytoskeletal adaptor activity actin cytoskeleton organization cell junction melanosome syndecan binding protein heterodimerization activity protein N-terminus binding
235967_at	0.369	5.836	3.011	8.671e-03	0.156	-2.592	LOC100127891	similar to hCG2042508	7		AV761120	100127891	7q32.2
1553072_at	0.276	3.949	3.010	8.686e-03	0.156	-2.593	BNIPL	BCL2/adenovirus E1B 19kD interacting protein like	1	149275652	NM_138279	149428	1q21.3	Hs.591473	12	nucleus cytosol apoptosis negative regulation of cell proliferation regulation of growth rate identical protein binding
200660_at	0.684	6.824	3.009	8.700e-03	0.156	-2.595	S100A11	S100 calcium binding protein A11	1	-150271605	NM_005620	6282	1q21	Hs.417004	41	ruffle calcium ion binding nucleus cytoplasm cytoplasm signal transduction negative regulation of DNA replication negative regulation of cell proliferation protein homodimerization activity S100 beta binding calcium-dependent protein binding
238890_at	-0.442	5.500	-3.009	8.705e-03	0.156	-2.595	PSMG1	proteasome (prosome, macropain) assembly chaperone 1	21	-39469253	AI791303	8624	21q22.3	Hs.473838	12	protein binding cytoplasm endoplasmic reticulum proteasome assembly
222916_s_at	-0.366	5.661	-3.008	8.714e-03	0.156	-2.596	HDLBP	high density lipoprotein binding protein	2	-241815351, -241815351	AF116718	3069	2q37.3	Hs.471851	25	RNA binding protein binding nucleus cytoplasm plasma membrane lipid metabolic process lipid transport steroid metabolic process cholesterol metabolic process lipid binding high-density lipoprotein particle
208972_s_at	0.350	11.130	3.008	8.720e-03	0.156	-2.597	ATP5G1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)	17	44325146	AL080089	516	17q21.32	Hs.80986	16	transporter activity mitochondrion mitochondrial proton-transporting ATP synthase complex ion transport lipid binding hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting ATP synthase complex, coupling factor F(o)	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
219667_s_at	0.232	2.368	3.008	8.723e-03	0.156	-2.597	BANK1	B-cell scaffold protein with ankyrin repeats 1	4	102930786, 102954005	NM_017935	55024	4q24	Hs.480400	11	B cell activation
201148_s_at	0.303	7.204	3.007	8.728e-03	0.156	-2.598	TIMP3	TIMP metallopeptidase inhibitor 3	22	31526801	AW338933	7078	22q12.1-q13.2 22q12.3	Hs.644633 Hs.714168	117	enzyme inhibitor activity protein binding extracellular region basement membrane visual perception metalloendopeptidase inhibitor activity response to organic cyclic substance tissue regeneration response to estrogen stimulus response to stimulus negative regulation of membrane protein ectodomain proteolysis
216304_x_at	-0.314	9.276	-3.007	8.729e-03	0.156	-2.598	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	AJ295618	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
235549_at	-0.678	4.321	-3.006	8.752e-03	0.156	-2.600	RNF144B	ring finger protein 144B	6	18495572	AL575512	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
221536_s_at	-0.481	6.968	-3.006	8.753e-03	0.156	-2.600	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	3	-195842806	AL136897	55341	3q29	Hs.518505	12	nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export
214523_at	0.335	5.034	3.004	8.785e-03	0.157	-2.604	CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon	14	-22656354	NM_001805	1053	14q11.2	Hs.558308	32	transcription factor activity nucleus nucleolus regulation of transcription, DNA-dependent phagocytosis macrophage differentiation cytokine biosynthetic process defense response to bacterium sequence-specific DNA binding protein dimerization activity
222771_s_at	0.282	2.820	3.004	8.790e-03	0.157	-2.604	MYEF2	myelin expression factor 2	15	-46218920	BF224052	50804	15q21.1	Hs.6638	5	nucleotide binding DNA binding RNA binding nucleus nucleolus Golgi apparatus transcription
205414_s_at	0.459	4.890	3.003	8.802e-03	0.157	-2.605	RICH2	Rho-type GTPase-activating protein RICH2	17	12633553	NM_014859	9912	17p12	Hs.499758	7	GTPase activator activity protein binding intracellular cytoplasm signal transduction
226671_at	-0.592	7.116	-3.003	8.804e-03	0.157	-2.606	LAMP2	lysosomal-associated membrane protein 2	X	-119454376, -119444030	AI150000	3920	Xq24	Hs.496684	52	membrane fraction lysosomal membrane late endosome plasma membrane plasma membrane integral to membrane platelet dense granule membrane platelet dense granule membrane	Lysosome
205161_s_at	0.516	5.494	3.003	8.805e-03	0.157	-2.606	PEX11A	peroxisomal biogenesis factor 11 alpha	15	-88027290	NM_003847	8800	15q26.1	Hs.31034	9	peroxisome peroxisomal membrane integral to peroxisomal membrane signal transduction membrane integral to membrane peroxisome fission
222389_s_at	-0.272	7.428	-3.003	8.809e-03	0.157	-2.606	WAC	WW domain containing adaptor with coiled-coil	10	28861432, 28862429	BE879807	51322		Hs.714700	15	protein binding nucleus nuclear speck
214663_at	-0.272	6.017	-3.003	8.809e-03	0.157	-2.606	DSTYK	dual serine/threonine and tyrosine protein kinase	1	-203378254	AB007941	25778	1q32.1	Hs.6874	9	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
220929_at	0.252	5.086	3.003	8.809e-03	0.157	-2.606	GALNT8	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)	12	4700012	NM_017417	26290	12p13.3	Hs.511985	2	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding	O-Glycan biosynthesis Metabolic pathways
213758_at	0.581	6.198	3.003	8.811e-03	0.157	-2.606	COX4I1	cytochrome c oxidase subunit IV isoform 1	16	84390696	AW337510	1327	16q22-qter	Hs.433419	17	cytochrome-c oxidase activity protein binding nucleus mitochondrion mitochondrial inner membrane generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
239877_at	0.220	2.935	3.003	8.813e-03	0.157	-2.607	LOC157740	hypothetical protein C8orf9	8		AI499833	157740	8p23.1	Hs.603618
1570432_at	-0.252	4.168	-3.002	8.825e-03	0.157	-2.608	LOC100133287	hypothetical protein LOC100133287	21		AF289552	100133287	21q22.3	Hs.684477
219414_at	0.522	3.711	3.002	8.825e-03	0.157	-2.608	CLSTN2	calsyntenin 2	3	141136716	NM_022131	64084	3q23-q24	Hs.158529	11	Golgi membrane calcium ion binding protein binding endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus plasma membrane cell adhesion homophilic cell adhesion integral to membrane postsynaptic membrane
223208_at	0.290	6.543	3.002	8.828e-03	0.157	-2.608	KCTD10	potassium channel tetramerisation domain containing 10	12	-108370842	AF113208	83892	12q24.11	Hs.524731 Hs.708437	10	voltage-gated potassium channel activity protein binding nucleus nucleolus cytoplasm potassium ion transport voltage-gated potassium channel complex membrane
203270_at	0.279	5.587	3.001	8.851e-03	0.157	-2.610	DTYMK	deoxythymidylate kinase (thymidylate kinase)	2	-242263829, -92952	NM_012145	1841	2q37.3	Hs.471873	12	nucleotide binding thymidylate kinase activity ATP binding cytosol dTDP biosynthetic process cell cycle cell proliferation nucleotide biosynthetic process kinase activity transferase activity nucleoside kinase activity	Pyrimidine metabolism Metabolic pathways
216926_s_at	0.264	3.891	3.000	8.865e-03	0.157	-2.612	KIAA0892	KIAA0892	19	19292629	AC003030	23383	19p13.11	Hs.654939 Hs.713004	8	chromatin protein binding extracellular region nucleus nucleoplasm cohesin loading complex maintenance of mitotic sister chromatid cohesion
229043_at	-0.546	6.264	-3.000	8.865e-03	0.157	-2.612	PAPD5	PAP associated domain containing 5	16	48745568	AI492902	64282	16q12.1	Hs.514342	5	molecular_function DNA binding DNA-directed DNA polymerase activity cellular_component nucleus DNA replication cell cycle mitosis biological_process transferase activity nucleotidyltransferase activity cell division
229763_at	0.348	5.288	2.999	8.872e-03	0.157	-2.613	FOXP4	forkhead box P4	6	41622141	BE504097	116113	6p21.1	Hs.131436	12	transcription factor activity intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
211621_at	-0.603	6.031	-2.999	8.880e-03	0.157	-2.614	AR	androgen receptor	X	66680598, 66705407	M73069	367	Xq11.2-q12	Hs.496240	1010	in utero embryonic development transcription factor activity receptor activity androgen receptor activity androgen receptor activity receptor binding androgen binding nucleus cytoplasm transport signal transduction cell-cell signaling sex differentiation cell death zinc ion binding cell proliferation male gonad development cell growth male somatic sex determination androgen receptor signaling pathway prostate gland development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter metal ion binding protein dimerization activity regulation of catalytic activity	Pathways in cancer Prostate cancer
225546_at	-0.670	7.510	-2.998	8.893e-03	0.158	-2.615	EEF2K	eukaryotic elongation factor-2 kinase	16	22125092	W68180	29904	16p12.2	Hs.498892	22	nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding ATP binding cytoplasm cytosol translational elongation protein amino acid phosphorylation translation factor activity, nucleic acid binding transferase activity
1567030_at	0.346	5.004	2.998	8.894e-03	0.158	-2.615	SH3GLP2	SH3-domain GRB2-like pseudogene 2	17		X99660	6459	17q11.2	Hs.684860 Hs.684861	2
225138_at	-0.513	7.678	-2.998	8.897e-03	0.158	-2.615	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	N52625	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
226424_at	0.363	5.998	2.997	8.912e-03	0.158	-2.617	CAPS	calcyphosine	19	5865192	AI683754	828	19p13.3	Hs.584744	13	calcium ion binding cytoplasm intracellular signaling cascade
209928_s_at	0.409	4.859	2.997	8.920e-03	0.158	-2.618	MSC	musculin (activated B-cell factor-1)	8	-72916330	AF060154	9242	8q21	Hs.442619	11	transcription factor activity transcription corepressor activity nucleus transcription from RNA polymerase II promoter regulation of transcription
210978_s_at	0.399	6.835	2.997	8.921e-03	0.158	-2.618	TAGLN2	transgelin 2	1	-158154526	BC002616	8407	1q21-q25	Hs.517168	12	protein binding plasma membrane muscle organ development nuclear membrane
207616_s_at	-0.496	8.047	-2.997	8.923e-03	0.158	-2.618	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	NM_004180	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
210987_x_at	0.468	8.130	2.996	8.940e-03	0.158	-2.620	TPM1	tropomyosin 1 (alpha)	15	61121890, 61121890, 61127688	M19267	7168	15q22.1	Hs.133892	76	stress fiber positive regulation of heart rate by epinephrine actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction cytoskeleton organization regulation of heart contraction structural constituent of muscle sarcomere muscle filament sliding negative regulation of cell migration ruffle organization bleb ruffle membrane positive regulation of ATPase activity cellular response to reactive oxygen species wound healing sarcomere organization positive regulation of cell adhesion positive regulation of stress fiber formation ventricular cardiac muscle morphogenesis cardiac muscle contraction	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
209711_at	-0.543	6.362	-2.996	8.940e-03	0.158	-2.620	SLC35D1	solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1	1	-67237603	N80922	23169	1p32-p31	Hs.213642	8	UDP-N-acetylgalactosamine transmembrane transporter activity endoplasmic reticulum carbohydrate transport UDP-N-acetylgalactosamine transport membrane integral to membrane integral to endoplasmic reticulum membrane chondroitin sulfate biosynthetic process
230938_x_at	0.319	7.105	2.995	8.944e-03	0.158	-2.620	ATF5	activating transcription factor 5	19	55123785	H48515	22809	19q13.3	Hs.9754	25	transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis sequence-specific DNA binding protein dimerization activity
212259_s_at	-0.398	7.591	-2.995	8.946e-03	0.158	-2.620	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	1	-153183179	BF344265	57326	1q21.3	Hs.505806	8	transcription corepressor activity protein binding nucleus cytoplasm cytosol cytoskeleton microtubule multicellular organismal development negative regulation of transcription cell differentiation
205417_s_at	-0.287	9.122	-2.995	8.947e-03	0.158	-2.620	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	3	49482568	NM_004393	1605	3p21	Hs.707131 Hs.76111	56	morphogenesis of an epithelial sheet calcium ion binding protein binding extracellular region basement membrane extracellular space membrane fraction cytoplasm integral to plasma membrane protein complex assembly muscle contraction actin cytoskeleton dystroglycan complex sarcolemma membrane raft	ECM-receptor interaction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
227310_at	0.245	3.014	2.995	8.949e-03	0.158	-2.621	ADSS	adenylosuccinate synthase	1	-242638418	AI346678	159	1cen-q12	Hs.498313	11	nucleotide binding magnesium ion binding immune system process adenylosuccinate synthase activity adenylosuccinate synthase activity GTP binding cellular_component cytoplasm purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process ligase activity phosphate binding	Purine metabolism Alanine, aspartate and glutamate metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
228837_at	0.299	5.702	2.995	8.954e-03	0.158	-2.621	TCF4	transcription factor 4	18	-51040559	BE857360	6925	18q21.1	Hs.605153	55	transcription factor activity protein binding nucleus regulation of transcription positive regulation of transcription, DNA-dependent protein heterodimerization activity
208680_at	-0.397	10.706	-2.995	8.954e-03	0.158	-2.621	PRDX1	peroxiredoxin 1	1	-45749293	L19184	5052	1p34.1	Hs.180909	62	skeletal system development protein binding nucleus cytoplasm mitochondrion cell proliferation oxidoreductase activity melanosome hydrogen peroxide catabolic process cell redox homeostasis peroxiredoxin activity oxidation reduction
244121_at	-0.529	3.663	-2.995	8.957e-03	0.158	-2.621	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	2	170392263	BE835502	130507	2q31.1	Hs.379548	7	suckling behavior ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process sensory perception of smell zinc ion binding embryonic development membrane integral to membrane ligase activity metal ion binding
240349_at	-0.423	5.553	-2.995	8.961e-03	0.158	-2.622	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	AV693202	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
222750_s_at	0.588	5.174	2.994	8.975e-03	0.158	-2.623	SRD5A3	steroid 5 alpha-reductase 3	4	55907165	BC002480	79644	4q12	Hs.39311	3	3-oxo-5-alpha-steroid 4-dehydrogenase activity cytoplasm endoplasmic reticulum microsome lipid metabolic process membrane integral to membrane oxidoreductase activity, acting on the CH-CH group of donors oxidation reduction	Androgen and estrogen metabolism
224771_at	0.337	4.972	2.993	8.981e-03	0.158	-2.624	NAV1	neuron navigator 1	1	199884072	AI937060	89796	1q32.3	Hs.585374	10	nucleotide binding cytoplasm cytoskeleton microtubule multicellular organismal development nervous system development nucleoside-triphosphatase activity cell differentiation
213155_at	0.493	5.945	2.993	8.984e-03	0.158	-2.624	WSCD1	WSC domain containing 1	17	5914657	AB011095	23302	17p13.2	Hs.370166	2	membrane integral to membrane
201197_at	-0.666	7.144	-2.992	9.008e-03	0.158	-2.627	AMD1	adenosylmethionine decarboxylase 1	6	111302679, 111302680	NM_001634	262	6q21-q22	Hs.159118	27	adenosylmethionine decarboxylase activity cellular_component spermine biosynthetic process spermidine biosynthetic process lyase activity	Cysteine and methionine metabolism Arginine and proline metabolism Metabolic pathways
211086_x_at	0.218	3.870	2.992	9.008e-03	0.158	-2.627	NEK1	NIMA (never in mitosis gene a)-related kinase 1	4	-170551003	Z25431	4750	4q33	Hs.481181	11	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division
210466_s_at	-0.274	10.033	-2.992	9.013e-03	0.158	-2.627	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	BC002488	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
1560834_a_at	0.233	4.971	2.992	9.017e-03	0.158	-2.628	RMST	rhabdomyosarcoma 2 associated transcript (non-protein coding)	12	96382929	AF429305	196475	12q21 12q23.1	Hs.652568	2
223314_at	0.341	5.831	2.990	9.037e-03	0.159	-2.630	TSPAN14	tetraspanin 14	10	82204017	BF025955	81619	10q23.1	Hs.310453	5	membrane integral to membrane
204688_at	0.528	6.545	2.990	9.041e-03	0.159	-2.630	SGCE	sarcoglycan, epsilon	7	-94052471	NM_003919	8910	7q21-q22	Hs.371199	46	calcium ion binding protein binding cytoplasm cytoskeleton plasma membrane integral to plasma membrane cell-matrix adhesion muscle organ development sarcoglycan complex
210855_at	0.238	4.501	2.990	9.048e-03	0.159	-2.631	GREB1	GREB1 protein	2	11591692, 11597530, 11600301	AF245390	9687	2p25.1	Hs.467733	11	membrane integral to membrane
214154_s_at	0.321	4.576	2.990	9.051e-03	0.159	-2.631	PKP2	plakophilin 2	12	-32834946	AA888057	5318	12p11	Hs.164384	29	protein binding nucleus cytoskeleton plasma membrane integral to membrane cell-cell adhesion desmosome	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
200848_at	-0.451	8.701	-2.989	9.054e-03	0.159	-2.631	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	AA479488	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
242331_x_at	-0.255	2.415	-2.989	9.071e-03	0.159	-2.633	LOC642236	similar to FRG1 protein (FSHD region gene 1 protein)	9		AV729462	642236	9q13	Hs.203772 Hs.529357 Hs.709700	1
209314_s_at	-0.575	7.257	-2.988	9.080e-03	0.159	-2.634	HBS1L	HBS1-like (S. cerevisiae)	6	-135398687, -135323215, -135323213	AK024258	10767	6q23-q24	Hs.378532	12	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation signal transduction
202898_at	0.311	5.374	2.988	9.083e-03	0.159	-2.634	SDC3	syndecan 3	1	-31114899	NM_014654	9672	1pter-p22.3	Hs.158287	35	cytoskeletal protein binding membrane integral to membrane	ECM-receptor interaction Cell adhesion molecules (CAMs)
228087_at	-0.309	7.124	-2.987	9.104e-03	0.159	-2.636	CCDC126	coiled-coil domain containing 126	7	23603522	AK026684	90693	7p15.3	Hs.232296	4	extracellular region
229565_x_at	0.280	4.057	2.986	9.123e-03	0.160	-2.638	TBX3	T-box 3	12	-113592441	N29712	6926	12q24.1	Hs.714737	28	skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis multicellular organismal development cell aging positive regulation of cell proliferation determination of anterior/posterior axis, embryo organ morphogenesis general transcriptional repressor activity male genitalia development female genitalia development mammary gland development luteinizing hormone secretion embryonic arm morphogenesis forelimb morphogenesis embryonic digit morphogenesis sequence-specific DNA binding negative regulation of myoblast differentiation positive regulation of cell cycle negative regulation of transcription, DNA-dependent follicle-stimulating hormone secretion mesoderm morphogenesis
228454_at	-0.376	7.571	-2.986	9.125e-03	0.160	-2.638	LCOR	ligand dependent nuclear receptor corepressor	10	98582726	AW663968	84458	10q24	Hs.500695	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity RNA polymerase II transcription factor activity nucleus transcription factor binding regulation of transcription
234302_s_at	-0.355	9.689	-2.986	9.125e-03	0.160	-2.638	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)	17	18027591	AL137263	54890	17p11.2	Hs.462392	5	membrane integral to membrane
209524_at	0.498	5.690	2.985	9.134e-03	0.160	-2.639	HDGFRP3	hepatoma-derived growth factor, related protein 3	15	-81597819	AK001280	50810	15q25.2	Hs.513954	9	nucleus cytoplasm growth factor activity cell proliferation
208383_s_at	0.531	2.944	2.985	9.143e-03	0.160	-2.640	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	20	55569542	NM_002591	5105	20q13.31	Hs.1872	40	magnesium ion binding phosphoenolpyruvate carboxykinase (GTP) activity phosphoenolpyruvate carboxykinase (GTP) activity GTP binding nucleus nucleolus cytoplasm centrosome cytosol gluconeogenesis lipid metabolic process lyase activity purine nucleotide binding manganese ion binding carboxylic acid binding response to insulin stimulus glucose homeostasis glycerol biosynthetic process from pyruvate	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways PPAR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway
208416_s_at	-0.336	6.444	-2.984	9.153e-03	0.160	-2.641	SPTB	spectrin, beta, erythrocytic	14	-64302901, -64282753	NM_000347	6710	14q23-q24.2	Hs.417303	62	structural constituent of cytoskeleton protein binding cytoplasm cell cortex spectrin spectrin-associated cytoskeleton actin cytoskeleton intrinsic to internal side of plasma membrane protein complex actin filament binding actin filament capping
209298_s_at	-0.691	6.219	-2.984	9.160e-03	0.160	-2.642	ITSN1	intersectin 1 (SH3 domain protein)	21	33936653, 33936653	AF114488	6453	21q22.1-q22.2	Hs.160324	39	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular intracellular signaling cascade membrane synaptosome lamellipodium cell junction regulation of Rho protein signal transduction synapse synaptic vesicle endocytosis
233632_s_at	-0.564	7.190	-2.983	9.167e-03	0.160	-2.643	XRN1	5'-3' exoribonuclease 1	3	-143508138	AL117516	54464	3q23	Hs.435103	12	DNA binding RNA binding protein binding intracellular cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5'-3' exonuclease activity hydrolase activity	RNA degradation
1569617_at	0.277	4.959	2.983	9.170e-03	0.160	-2.643	OSBP2	oxysterol binding protein 2	22	29420792	BC018025	23762	22q12.2	Hs.517546	11	lipid transport steroid metabolic process membrane
204716_at	-0.396	3.852	-2.983	9.184e-03	0.160	-2.644	CCDC6	coiled-coil domain containing 6	10	-61218526	NM_005436	8030	10q21	Hs.591360	20	structural constituent of cytoskeleton protein binding cellular_component cytoplasm cytoskeleton biological_process SH3 domain binding	Pathways in cancer Thyroid cancer
213474_at	0.276	5.735	2.981	9.207e-03	0.161	-2.647	KCTD7	potassium channel tetramerisation domain containing 7	7	65731324	AI890903	154881	7q11.21	Hs.546627	6	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
211686_s_at	-0.388	6.971	-2.981	9.216e-03	0.161	-2.648	MAK16	MAK16 homolog (S. cerevisiae)	8	33462226	AF251062	84549	8p12	Hs.583805	10	nucleus nucleolus
226202_at	-0.458	4.773	-2.980	9.239e-03	0.161	-2.650	ZNF398	zinc finger protein 398	7	148454440, 148475492	AI761824	57541	7q36.1	Hs.654721	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription activator activity metal ion binding
205008_s_at	0.660	6.424	2.979	9.242e-03	0.161	-2.650	CIB2	calcium and integrin binding family member 2	15	-76184045	NM_006383	10518	15q24	Hs.129867	6	calcium ion binding protein binding
229653_at	-0.300	5.565	-2.979	9.254e-03	0.161	-2.651	VPS53	vacuolar protein sorting 53 homolog (S. cerevisiae)	17	-382282, -361479	AA514634	55275	17p13.3	Hs.461819	11	endosome Golgi apparatus protein transport membrane
218307_at	0.330	7.716	2.978	9.267e-03	0.161	-2.653	RSAD1	radical S-adenosyl methionine domain containing 1	17	45911188	NM_018346	55316	17q21.33	Hs.8033	3	coproporphyrinogen oxidase activity iron ion binding cytoplasm mitochondrion porphyrin biosynthetic process oxidoreductase activity metal ion binding 4 iron, 4 sulfur cluster binding oxidation reduction
227298_at	0.286	5.515	2.978	9.268e-03	0.161	-2.653	FLJ37798	hypothetical gene supported by AK095117	6		AI806330	401264	6p12.3	Hs.544586	1
217978_s_at	-0.268	7.870	-2.978	9.275e-03	0.161	-2.653	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	1	-152787674	NM_017582	55585	1q21.3	Hs.607928	7	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
228568_at	1.116	6.963	2.978	9.276e-03	0.161	-2.653	GCOM1	GRINL1A complex locus	15	55671405, 55671405	AI926697	145781	15q21.3	Hs.437256	7
209896_s_at	-0.944	6.546	-2.978	9.279e-03	0.161	-2.654	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	AF119855	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
1554761_a_at	-0.421	5.634	-2.977	9.284e-03	0.161	-2.654	HEATR2	HEAT repeat containing 2	7	732863	BC010850	54919	7p22.3	Hs.535896	8	protein binding
209326_at	-0.433	5.845	-2.977	9.284e-03	0.161	-2.654	SLC35A2	solute carrier family 35 (UDP-galactose transporter), member A2	X	-48645833, -48645832, -48645402	D84454	7355	Xp11.23-p11.22	Hs.21899	12	Golgi membrane nucleotide-sugar transmembrane transporter activity sugar:hydrogen symporter activity UDP-galactose transmembrane transporter activity Golgi apparatus galactose metabolic process nucleotide-sugar transport UDP-galactose transport membrane integral to membrane
238148_s_at	0.452	4.736	2.977	9.285e-03	0.161	-2.654	ZNF818P	zinc finger protein 818 pseudogene	19		AI651641	390963	19q13.42	Hs.444446		DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
208329_at	0.280	2.993	2.977	9.293e-03	0.161	-2.655	PBOV1	prostate and breast cancer overexpressed 1	6	-138578819	NM_021635	59351	6q23-q24	Hs.302016	6	nucleus cytoplasm
1558668_s_at	0.424	2.445	2.976	9.317e-03	0.162	-2.658	SPATA22	spermatogenesis associated 22	17	-3290063	AW072392	84690	17p13.3	Hs.351068	3
202460_s_at	0.401	4.845	2.975	9.318e-03	0.162	-2.658	LPIN2	lipin 2	18	-2906991	NM_014646	9663	18p11.31	Hs.132342	10	nucleus phosphatidate phosphatase activity
236050_at	0.262	5.484	2.975	9.322e-03	0.162	-2.658	C11orf35	chromosome 11 open reading frame 35	11	-544856	AI656897	256329	11p15.5	Hs.669395	2
212131_at	-0.524	8.418	-2.975	9.325e-03	0.162	-2.658	LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)	19	39355191	BG054966	26065	19q13.11	Hs.718430	6
227994_x_at	0.531	8.313	2.975	9.330e-03	0.162	-2.659	PPDPF	pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)	20	61622576	AA548838	79144	20q13.33	Hs.79625	3	multicellular organismal development cell differentiation
235426_at	0.266	4.629	2.975	9.335e-03	0.162	-2.659	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	AW293951	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
209320_at	0.266	6.168	2.974	9.343e-03	0.162	-2.660	ADCY3	adenylate cyclase 3	2	-24895541	AF033861	109	2p23.3	Hs.467898	28	nucleotide binding magnesium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane cAMP biosynthetic process female meiosis intracellular signaling cascade sensory perception of smell calcium- and calmodulin-responsive adenylate cyclase activity membrane raft response to stimulus	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Olfactory transduction GnRH signaling pathway Melanogenesis Vibrio cholerae infection
212871_at	-0.515	5.925	-2.974	9.354e-03	0.162	-2.661	MAPKAPK5	mitogen-activated protein kinase-activated protein kinase 5	12	110764661	NM_003668	8550	12q24.12-q24.13	Hs.413901	16	nucleotide binding protein serine/threonine kinase activity MAP kinase kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction transferase activity	MAPK signaling pathway
203921_at	0.275	4.537	2.973	9.368e-03	0.162	-2.662	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2	3	144321357	NM_004267	9435	3q24	Hs.8786	19	N-acetylglucosamine 6-O-sulfotransferase activity Golgi apparatus trans-Golgi network carbohydrate metabolic process N-acetylglucosamine metabolic process sulfur metabolic process inflammatory response multicellular organismal development membrane integral to membrane transferase activity intrinsic to Golgi membrane	Keratan sulfate biosynthesis Metabolic pathways
215429_s_at	0.321	6.481	2.973	9.368e-03	0.162	-2.663	ZNF428	zinc finger protein 428	19	-48803216	BE045982	126299	19q13.31	Hs.719387 Hs.99093	2	intracellular zinc ion binding metal ion binding
213165_at	-0.511	8.183	-2.973	9.368e-03	0.162	-2.663	CEP350	centrosomal protein 350kDa	1	178190530	AI041204	9857	1p36.13-q41	Hs.413045	17	nucleus centrosome spindle
223279_s_at	-0.391	9.371	-2.973	9.373e-03	0.162	-2.663	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	15	-68733946, -68733946	AF322916	55075	15q22-q24	Hs.108049	12	molecular_function protein binding extracellular region membrane fraction soluble fraction nucleus nuclear envelope cytoplasm cytosol cytoskeleton DNA damage response, signal transduction resulting in induction of apoptosis induction of apoptosis by oxidative stress response to UV viral reproduction positive regulation of protein import into nucleus negative regulation of NF-kappaB import into nucleus positive regulation of apoptosis positive regulation of caspase activity apoptosome perinuclear region of cytoplasm negative regulation of inflammatory response
201721_s_at	0.608	5.930	2.973	9.373e-03	0.162	-2.663	LAPTM5	lysosomal protein transmembrane 5	1	-30977901	NM_006762	7805	1p34	Hs.371021	8	lysosomal membrane integral to plasma membrane transport membrane	Lysosome
230683_at	0.299	3.848	2.973	9.374e-03	0.162	-2.663	ANKRD60	ankyrin repeat domain 60	20		W56760	140731	20q13.32		1
217853_at	0.657	8.284	2.972	9.377e-03	0.162	-2.663	TNS3	tensin 3	7	-47281276	NM_022748	64759	7p12.3	Hs.520814	12	protein binding nucleus nucleolus cytoplasm plasma membrane focal adhesion positive regulation of cell proliferation cell migration cell junction lung alveolus development
225551_at	-0.717	7.161	-2.972	9.386e-03	0.162	-2.664	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	AW291187	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
238125_at	0.342	4.682	2.971	9.399e-03	0.162	-2.666	ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif, 16	5	5193442	AI740544	170690	5p15	Hs.661915	4	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
225447_at	-0.692	7.547	-2.971	9.401e-03	0.162	-2.666	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	2	157000210, 157001145	AA613031	2820	2q24.1	Hs.512382	20	glycerol-3-phosphate dehydrogenase activity calcium ion binding mitochondrion mitochondrial inner membrane glycerol-3-phosphate metabolic process gluconeogenesis glycerol-3-phosphate dehydrogenase complex oxidoreductase activity oxidation reduction	Glycerophospholipid metabolism
225897_at	0.519	6.577	2.971	9.406e-03	0.162	-2.666	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	AI709406	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
1558044_s_at	0.501	7.195	2.971	9.409e-03	0.162	-2.667	EXOSC6	exosome component 6	16	-68841634	BF692729	118460	16q22.1	Hs.660633 Hs.719211	9	3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity	RNA degradation
223176_at	-0.496	5.931	-2.971	9.411e-03	0.162	-2.667	KCTD20	potassium channel tetramerisation domain containing 20	6	36518521	BC003697	222658	6p21.31	Hs.188757	4	voltage-gated potassium channel activity potassium ion transport voltage-gated potassium channel complex membrane identical protein binding
215590_x_at	-0.421	6.356	-2.971	9.412e-03	0.162	-2.667	LOC100128640	hypothetical protein LOC100128640	3		AK025619	100128640	3p22.2
224718_at	-0.347	6.823	-2.969	9.441e-03	0.163	-2.670	YY1	YY1 transcription factor	14	99774854	AK025731	7528	14q	Hs.388927	97	transcription factor activity transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus transcription factor complex plasma membrane regulation of transcription from RNA polymerase II promoter zinc ion binding anterior/posterior pattern formation nuclear matrix PcG protein complex metal ion binding camera-type eye morphogenesis
201670_s_at	0.465	6.420	2.969	9.445e-03	0.163	-2.670	MARCKS	myristoylated alanine-rich protein kinase C substrate	6	114285219	M68956	4082	6q22.2	Hs.519909 Hs.712721	41	protein kinase C binding calmodulin binding cytoplasm centrosome cell cortex actin cytoskeleton membrane germinal vesicle actin filament binding	Fc gamma R-mediated phagocytosis
200934_at	-0.718	9.031	-2.969	9.449e-03	0.163	-2.670	DEK	DEK oncogene	6	-18332380, -18332378	NM_003472	7913	6p22.3	Hs.484813	55	DNA binding specific RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter signal transduction viral genome replication histone binding
202305_s_at	-0.628	8.832	-2.968	9.452e-03	0.163	-2.671	FEZ2	fasciculation and elongation protein zeta 2 (zygin II)	2	-36632904	AI685892	9637	2p21	Hs.258563	9	protein binding signal transduction nervous system development axon guidance
225663_at	-0.420	8.809	-2.968	9.453e-03	0.163	-2.671	ACBD5	acyl-Coenzyme A binding domain containing 5	10	-27524149, -27524149	AL047650	91452	10p12.1	Hs.530597	4	acyl-CoA binding transport lipid binding membrane integral to membrane
229500_at	-0.434	4.475	-2.968	9.464e-03	0.163	-2.672	SLC30A9	solute carrier family 30 (zinc transporter), member 9	4	41687279	AI609256	10463	4p13-p12	Hs.479634	6	nucleotide binding transcription factor activity nucleus cytoskeleton cation transport zinc ion transport biological_process zinc ion binding cation transmembrane transporter activity membrane integral to membrane regulation of transcription
211185_s_at	-0.320	9.862	-2.967	9.473e-03	0.163	-2.673	SF3B1	splicing factor 3b, subunit 1, 155kDa	2	-197991765, -197964942	AF130099	23451	2q33.1	Hs.632554	34	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome protein binding nucleus spliceosomal complex RNA splicing nuclear speck RNA splicing factor activity, transesterification mechanism
232874_at	0.527	4.632	2.967	9.487e-03	0.163	-2.674	DOCK9	dedicator of cytokinesis 9	13	-98310435, -98310435, -98243741, -98243741	AU146550	23348	13q32.3	Hs.596105	15	guanyl-nucleotide exchange factor activity GTP binding cellular_component biological_process membrane GTPase binding
205485_at	-0.411	10.664	-2.967	9.489e-03	0.163	-2.674	RYR1	ryanodine receptor 1 (skeletal)	19	43616179	NM_000540	6261	19q13.1	Hs.466664	130	response to hypoxia receptor activity ion channel activity ryanodine-sensitive calcium-release channel activity calcium ion binding calmodulin binding cytoplasm smooth endoplasmic reticulum plasma membrane integral to plasma membrane cell cortex ion transport calcium ion transport muscle contraction junctional sarcoplasmic reticulum membrane terminal cisterna calcium-release channel activity response to caffeine I band release of sequestered calcium ion into cytosol cytosolic calcium ion homeostasis	Calcium signaling pathway Long-term depression
204742_s_at	-0.438	6.154	-2.966	9.499e-03	0.163	-2.675	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	13	32058591	NM_015032	23047	13q12.3	Hs.716441	15	chromatin DNA binding ATP binding nucleus cell cycle mitotic sister chromatid cohesion mitosis negative regulation of cell proliferation identical protein binding cell division
226735_at	-0.455	7.036	-2.965	9.518e-03	0.163	-2.677	TAPT1	transmembrane anterior posterior transformation 1	4	-15771225	AI239899	202018	4p15.32	Hs.479223	5	receptor activity multicellular organismal development membrane integral to membrane
209823_x_at	0.442	6.289	2.965	9.522e-03	0.163	-2.678	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	6	-32735634	M17955	3119	6p21.3	Hs.409934 Hs.534322 Hs.713773	998	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane immune response immune response membrane membrane integral to membrane MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
235167_at	-0.579	5.360	-2.965	9.523e-03	0.163	-2.678	LOC100190986	hypothetical LOC100190986	16	-21783123, -21350846, 22423270	BE972419	100190986	16p12.2	Hs.611072 Hs.648439	2
1554462_a_at	-0.696	7.075	-2.965	9.524e-03	0.163	-2.678	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	AF115512	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
1553528_a_at	-0.420	4.113	-2.965	9.528e-03	0.163	-2.678	TAF5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	10	105117713	NM_139052	6877	10q24-q25.2	Hs.96103	37	transcription factor activity transcription factor activity histone acetyltransferase activity nucleus nucleoplasm transcription factor TFIID complex nucleolus cytoplasm cytoskeleton transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter promoter binding chromatin modification transcription initiation factor activity transcription factor TFTC complex interspecies interaction between organisms regulation of transcription protein dimerization activity	Basal transcription factors
213373_s_at	0.474	4.414	2.964	9.530e-03	0.163	-2.678	CASP8	caspase 8, apoptosis-related cysteine peptidase	2	201806410, 201806410, 201830998, 201833467	BF439983	841	2q33-q34	Hs.599762	362	cysteine-type endopeptidase activity nucleus cytoplasm mitochondrion cytosol cytoskeleton peptidase activity induction of apoptosis by extracellular signals induction of apoptosis by extracellular signals activation of pro-apoptotic gene products death-inducing signaling complex response to tumor necrosis factor identical protein binding regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade proteolysis involved in cellular protein catabolic process	p53 signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Alzheimer's disease Huntington's disease Pathways in cancer
223412_at	-0.707	5.430	-2.963	9.552e-03	0.163	-2.680	KBTBD7	kelch repeat and BTB (POZ) domain containing 7	13	-40663710	AL136782	84078	13q14.11	Hs.63841	9	molecular_function protein binding cellular_component biological_process
209147_s_at	-0.395	9.090	-2.963	9.562e-03	0.164	-2.681	PPAP2A	phosphatidic acid phosphatase type 2A	5	-54756439	AB000888	8611	5q11	Hs.696231	20	membrane fraction cytosol plasma membrane integral to plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity negative regulation of cell proliferation germ cell migration hydrolase activity regulation of lipid metabolic process androgen receptor signaling pathway phospholipid dephosphorylation	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
1558166_at	0.275	3.666	2.962	9.568e-03	0.164	-2.682	MGC16275	hypothetical protein MGC16275	17	-69717735	BM824870	85001	17q25.1	Hs.706954	1
223022_s_at	-0.448	7.699	-2.962	9.569e-03	0.164	-2.682	VTA1	Vps20-associated 1 homolog (S. cerevisiae)	6	142510102	AL136684	51534	6q24.1	Hs.431367	12	cytoplasm endosome protein transport membrane	Endocytosis
232024_at	0.737	5.023	2.962	9.571e-03	0.164	-2.682	GIMAP2	GTPase, IMAP family member 2	7	150013726	AI431931	26157	7q36.1	Hs.647071	5	nucleotide binding GTP binding membrane integral to membrane
1561281_a_at	0.267	3.189	2.962	9.581e-03	0.164	-2.683	LOC284576	hypothetical protein LOC284576	1		AK090497	284576	1q32.1	Hs.585440	1
226758_at	0.370	7.640	2.962	9.585e-03	0.164	-2.684	LUC7L2	LUC7-like 2 (S. cerevisiae)	7	138695173	AA043552	51631	7q34	Hs.718441	16	zinc ion binding enzyme binding metal ion binding
1564166_s_at	0.345	4.847	2.961	9.602e-03	0.164	-2.685	PRKRIP1	PRKR interacting protein 1 (IL11 inducible)	7	101823808	AK098276	79706	7q22.1	Hs.406395	6	double-stranded RNA binding protein kinase inhibitor activity protein binding nucleus nucleolus negative regulation of protein kinase activity protein kinase binding negative regulation of phosphorylation
236217_at	0.272	2.847	2.961	9.604e-03	0.164	-2.685	SLC31A1	solute carrier family 31 (copper transporters), member 1	9	115023628	AI885320	1317	9q31-q32	Hs.532315	24	copper ion transmembrane transporter activity copper ion binding integral to plasma membrane ion transport copper ion transport membrane
1558841_at	-0.275	4.430	-2.961	9.607e-03	0.164	-2.686	SDCCAG10	serologically defined colon cancer antigen 10	5	64100510	AL833769	10283	5q12.3	Hs.371372	6	peptidyl-prolyl cis-trans isomerase activity nucleus protein folding isomerase activity
218744_s_at	-0.482	8.410	-2.960	9.621e-03	0.164	-2.687	PACSIN3	protein kinase C and casein kinase substrate in neurons 3	11	-47155656	NM_016223	29763	11p12-p11.12	Hs.334639	14	cytoplasm plasma membrane cytoskeletal protein binding negative regulation of endocytosis positive regulation of membrane protein ectodomain proteolysis
213789_at	0.249	5.459	2.959	9.631e-03	0.164	-2.688	EBP	emopamil binding protein (sterol isomerase)	X	48265107	N58493	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
227327_at	0.295	6.709	2.959	9.637e-03	0.164	-2.689	MEGF8	multiple EGF-like-domains 8	19	47521600	BF062538	1954	19q12	Hs.132483	6	structural molecule activity calcium ion binding cellular_component biological_process membrane integral to membrane
212538_at	0.409	7.318	2.959	9.641e-03	0.164	-2.689	DOCK9	dedicator of cytokinesis 9	13	-98310435, -98310435, -98243741, -98243741	AL576253	23348	13q32.3	Hs.596105	15	guanyl-nucleotide exchange factor activity GTP binding cellular_component biological_process membrane GTPase binding
218584_at	0.306	6.253	2.959	9.642e-03	0.164	-2.689	TCTN1	tectonic family member 1	12	109536262	NM_024549	79600	12q24.11	Hs.211511 Hs.694390	5	extracellular region multicellular organismal development
203664_s_at	-0.412	5.923	-2.958	9.650e-03	0.164	-2.690	POLR2D	polymerase (RNA) II (DNA directed) polypeptide D	2	-128320310	NM_004805	5433	2q21	Hs.554831	80	nucleotide binding nuclear mRNA splicing, via spliceosome catalytic activity DNA-directed RNA polymerase activity nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter cellular metabolic process	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
202500_at	-0.272	8.154	-2.958	9.650e-03	0.164	-2.690	DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	2	219852283	NM_006736	3300	2q32-q34	Hs.77768	17	protein folding response to unfolded protein heat shock protein binding unfolded protein binding
216598_s_at	0.694	5.232	2.958	9.656e-03	0.164	-2.690	CCL2	chemokine (C-C motif) ligand 2	17	29606408	S69738	6347	17q11.2-q12	Hs.303649	505	G-protein-coupled receptor binding positive regulation of endothelial cell proliferation monocyte chemotaxis protein kinase activity signal transducer activity extracellular region extracellular space cytoplasm protein amino acid phosphorylation cellular calcium ion homeostasis anti-apoptosis chemotaxis inflammatory response humoral immune response cell adhesion transforming growth factor beta receptor signaling pathway G-protein signaling, coupled to cyclic nucleotide second messenger JAK-STAT cascade chemokine activity response to bacterium organ morphogenesis viral genome replication cytokine-mediated signaling pathway CCR2 chemokine receptor binding cell soma vascular endothelial growth factor receptor signaling pathway macrophage chemotaxis	Cytokine-cytokine receptor interaction Chemokine signaling pathway
221426_s_at	0.260	5.519	2.957	9.672e-03	0.164	-2.692	OR3A3	olfactory receptor, family 3, subfamily A, member 3	17	3270611	NM_012373	8392	17p13.3	Hs.532689	8	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
207177_at	0.271	2.924	2.957	9.674e-03	0.164	-2.692	PTGFR	prostaglandin F receptor (FP)	1	78729315	NM_000959	5737	1p31.1	Hs.654365	38	receptor activity G-protein coupled receptor activity prostaglandin F receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway parturition	Calcium signaling pathway Neuroactive ligand-receptor interaction
205413_at	-1.529	6.229	-2.957	9.686e-03	0.164	-2.693	MPPED2	metallophosphoesterase domain containing 2	11	-30388194, -30362615	NM_001584	744	11p13	Hs.289795	8	nervous system development hydrolase activity
200870_at	-0.371	10.211	-2.956	9.688e-03	0.164	-2.693	STRAP	serine/threonine kinase receptor associated protein	12	15926554	NM_007178	11171	12p12.3	Hs.719087	23	nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing identical protein binding
209661_at	0.349	5.987	2.956	9.692e-03	0.165	-2.694	KIFC3	kinesin family member C3	16	-56349629, -56349629	BC001211	3801	16q13-q21	Hs.23131	10	nucleotide binding microtubule motor activity ATP binding Golgi apparatus kinesin complex microtubule microtubule-based movement Golgi organization visual perception
223019_at	0.289	6.214	2.956	9.701e-03	0.165	-2.695	FAM129B	family with sequence similarity 129, member B	9	-129307438, -129307438	BC001979	64855	9q33.3-q34.11	Hs.522401	8
202625_at	0.333	3.374	2.955	9.707e-03	0.165	-2.695	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	8	56954939	AI356412	4067	8q13	Hs.699154	216	nucleotide binding non-membrane spanning protein tyrosine kinase activity receptor signaling protein tyrosine kinase activity protein binding protein binding ATP binding nucleus cytoplasm Golgi apparatus plasma membrane plasma membrane protein amino acid phosphorylation signal transduction positive regulation of cell proliferation response to hormone stimulus transferase activity erythrocyte differentiation positive regulation of tyrosine phosphorylation of STAT protein interspecies interaction between organisms membrane raft	Chemokine signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term depression Epithelial cell signaling in Helicobacter pylori infection
230179_at	-0.575	7.684	-2.955	9.717e-03	0.165	-2.696	LOC285812	hypothetical protein LOC285812	6		N52572	285812	6p23	Hs.593631
201660_at	-0.448	8.855	-2.955	9.717e-03	0.165	-2.696	ACSL3	acyl-CoA synthetase long-chain family member 3	2	223433975	AL525798	2181	2q34-q35	Hs.655772	20	nucleotide binding magnesium ion binding fatty-acyl-CoA synthase activity long-chain-fatty-acid-CoA ligase activity protein binding ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
36612_at	-0.445	6.374	-2.955	9.722e-03	0.165	-2.696	FAM168A	family with sequence similarity 168, member A	11	-72794675	D87470	23201	11q13.4	Hs.475334	3
212192_at	0.615	7.766	2.954	9.729e-03	0.165	-2.697	KCTD12	potassium channel tetramerisation domain containing 12	13	-76352304	AI718937	115207	13q22.3	Hs.644125	14	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
202980_s_at	-0.475	5.526	-2.954	9.733e-03	0.165	-2.698	SIAH1	seven in absentia homolog 1 (Drosophila)	16	-46951954, -46951946	AI953523	6477	16q12	Hs.295923	64	ubiquitin-protein ligase activity nucleus cytoplasm proteolysis ubiquitin-dependent protein catabolic process apoptosis cell cycle multicellular organismal development spermatogenesis nervous system development axon guidance protein C-terminus binding zinc ion binding anatomical structure morphogenesis protein ubiquitination ligase activity cell differentiation metal ion binding	p53 signaling pathway Ubiquitin mediated proteolysis Wnt signaling pathway
224881_at	-0.434	7.082	-2.954	9.736e-03	0.165	-2.698	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1	7	64975691	AV724827	154807	7q11.21	Hs.427232	5	membrane integral to membrane
225130_at	-0.275	5.923	-2.954	9.737e-03	0.165	-2.698	ZRANB1	zinc finger, RAN-binding domain containing 1	10	126620681	AW003734	54764	10q26.13	Hs.595158	3	ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process positive regulation of Wnt receptor signaling pathway metal ion binding
217886_at	-0.525	7.908	-2.953	9.749e-03	0.165	-2.699	EPS15	epidermal growth factor receptor pathway substrate 15	1	-51592523, -51592522	BF213575	2060	1p32	Hs.83722	63	calcium ion binding protein binding cytoplasm endosome cytosol plasma membrane coated pit epidermal growth factor receptor signaling pathway cell proliferation protein transport vesicle organization SH3 domain binding	Endocytosis
214505_s_at	-0.801	12.494	-2.953	9.762e-03	0.165	-2.700	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF220153	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
220663_at	0.301	4.602	2.952	9.772e-03	0.165	-2.701	IL1RAPL1	interleukin 1 receptor accessory protein-like 1	X	28515601	NM_014271	11141	Xp22.1-p21.3	Hs.658912	18	transmembrane receptor activity signal transduction learning or memory membrane integral to membrane innate immune response
209502_s_at	0.385	4.050	2.952	9.781e-03	0.165	-2.702	BAIAP2	BAI1-associated protein 2	17	76623541, 76623541	BC002495	10458	17q25	Hs.128316	37	ruffle cytoplasm plasma membrane signal transduction axonogenesis protein C-terminus binding cytoskeletal adaptor activity insulin receptor signaling pathway SH3 domain binding filopodium filopodium assembly	Adherens junction Regulation of actin cytoskeleton
232204_at	0.444	4.408	2.951	9.786e-03	0.165	-2.703	EBF1	early B-cell factor 1	5	-158055500	AF208502	1879	5q34	Hs.573143	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding transcription regulator activity metal ion binding
1555905_a_at	-0.979	4.532	-2.951	9.788e-03	0.165	-2.703	C3orf23	chromosome 3 open reading frame 23	3	44354614, 44354947, 44354947	AI147556	285343	3p21.31	Hs.55131	8	mitochondrion
223014_at	-0.337	9.545	-2.951	9.792e-03	0.165	-2.703	UBE2R2	ubiquitin-conjugating enzyme E2R 2	9	33807181	BC004862	54926	9p13.3	Hs.718444	9	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
229368_s_at	-0.331	5.140	-2.951	9.801e-03	0.165	-2.704	ZFAND5	zinc finger, AN1-type domain 5	9	-74156160	AI658995	7763	9q13-q21	Hs.406096	6	in utero embryonic development vasculature development respiratory system process molecular_function DNA binding cellular_component biological_process zinc ion binding fibroblast migration metal ion binding platelet-derived growth factor receptor signaling pathway skeletal system morphogenesis smooth muscle tissue development face development
204897_at	0.530	6.772	2.951	9.803e-03	0.165	-2.704	PTGER4	prostaglandin E receptor 4 (subtype EP4)	5	40715788	AA897516	5734	5p13.1	Hs.199248	63	receptor activity G-protein coupled receptor activity prostaglandin E receptor activity plasma membrane immune response signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger integral to membrane regulation of ossification	Neuroactive ligand-receptor interaction
228135_at	-0.402	7.598	-2.951	9.805e-03	0.165	-2.704	C1orf52	chromosome 1 open reading frame 52	1	-85488226	AA738437	148423	1p22.3	Hs.26226	7
201807_at	-0.287	8.724	-2.950	9.821e-03	0.165	-2.706	VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)	10	70553913	NM_004896	9559	10q21.1	Hs.499925	17	protein binding cytoplasm endosome cytosol vacuolar transport protein transporter activity protein transport membrane retromer complex retrograde transport, endosome to Golgi
220495_s_at	-0.316	7.451	-2.950	9.821e-03	0.165	-2.706	TXNDC15	thioredoxin domain containing 15	5	134237358	NM_024715	79770	5q31.1	Hs.696335	7	membrane integral to membrane cell redox homeostasis
1556854_at	0.510	2.878	2.950	9.821e-03	0.165	-2.706	LOC283501	hypothetical protein LOC283501	13		AA921835	283501	13q34	Hs.666761	1
201071_x_at	-0.305	9.823	-2.950	9.824e-03	0.165	-2.706	SF3B1	splicing factor 3b, subunit 1, 155kDa	2	-197991765, -197964942	NM_012433	23451	2q33.1	Hs.632554	34	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome protein binding nucleus spliceosomal complex RNA splicing nuclear speck RNA splicing factor activity, transesterification mechanism
212206_s_at	-0.552	7.769	-2.949	9.832e-03	0.165	-2.707	H2AFV	H2A histone family, member V	7	-44839737, -44833012	BF343852	94239	7p13	Hs.488189	12	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
231810_at	0.375	6.077	2.949	9.834e-03	0.165	-2.707	BRI3BP	BRI3 binding protein	12	124044146	BG106919	140707	12q24.31	Hs.596464	5	membrane integral to membrane
214252_s_at	0.406	5.333	2.948	9.848e-03	0.166	-2.708	CLN5	ceroid-lipofuscinosis, neuronal 5	13	76464059	AV700514	1203	13q21.1-q32	Hs.30213	19	protein binding lysosomal membrane vacuolar lumen endoplasmic reticulum Golgi apparatus lysosomal lumen acidification brain development visual perception integral to membrane integral to membrane neurogenesis protein catabolic process neuron maturation perinuclear region of cytoplasm	Lysosome
218025_s_at	0.375	10.491	2.948	9.848e-03	0.166	-2.708	PECI	peroxisomal D3,D2-enoyl-CoA isomerase	6	-4060925	NM_006117	10455	6p24.3	Hs.15250	15	acyl-CoA binding dodecenoyl-CoA delta-isomerase activity binding peroxisome peroxisomal matrix fatty acid metabolic process metabolic process isomerase activity	Fatty acid metabolism
210105_s_at	0.375	6.759	2.948	9.856e-03	0.166	-2.709	FYN	FYN oncogene related to SRC, FGR, YES	6	-112089177, -112089177, -112089177	M14333	2534	6q21	Hs.390567	326	nucleotide binding glycoprotein binding non-membrane spanning protein tyrosine kinase activity ATP binding endosome cytosol plasma membrane protein amino acid phosphorylation calcium ion transport protein kinase cascade multicellular organismal development learning feeding behavior transferase activity manganese ion binding identical protein binding interspecies interaction between organisms metal ion binding T cell receptor signaling pathway	Axon guidance Focal adhesion Adherens junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway Prion diseases Pathogenic Escherichia coli infection - EHEC
226212_s_at	-0.487	6.099	-2.947	9.876e-03	0.166	-2.711	INSR	insulin receptor	19	-7063265	AV726689	3643	19p13.3-p13.2	Hs.465744	351	nucleotide binding activation of MAPK activity positive regulation of protein amino acid phosphorylation heart morphogenesis receptor signaling protein tyrosine kinase activity receptor activity insulin receptor activity insulin-like growth factor receptor binding ATP binding GTP binding endosome microsome cytosol plasma membrane plasma membrane insulin receptor complex caveola carbohydrate metabolic process G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation positive regulation of cell proliferation insulin receptor signaling pathway endosome membrane transferase activity peptidyl-tyrosine phosphorylation transformation of host cell by virus protein phosphatase binding male sex determination positive regulation of cell migration insulin-like growth factor I binding insulin-like growth factor II binding activation of protein kinase B activity regulation of gene-specific transcription SH2 domain binding glucose homeostasis positive regulation of MAPKKK cascade 3-phosphoinositide-dependent protein kinase binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of nitric oxide biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of DNA replication positive regulation of glycolysis positive regulation of mitosis regulation of embryonic development positive regulation of glucose import positive regulation of glucose import protein amino acid autophosphorylation positive regulation of developmental growth protein heterotetramerization PTB domain binding positive regulation of protein kinase B signaling cascade positive regulation of respiratory burst	Adherens junction Insulin signaling pathway Type II diabetes mellitus
206388_at	0.286	5.122	2.947	9.880e-03	0.166	-2.711	PDE3A	phosphodiesterase 3A, cGMP-inhibited	12	20413463	U36798	5139	12p12	Hs.591150	24	oocyte maturation 3',5'-cyclic-AMP phosphodiesterase activity cGMP-inhibited cyclic-nucleotide phosphodiesterase activity soluble fraction insoluble fraction lipid metabolic process signal transduction membrane hydrolase activity regulation of meiosis response to drug	Purine metabolism Insulin signaling pathway
232553_at	0.247	2.880	2.947	9.886e-03	0.166	-2.712	PCYT1B	phosphate cytidylyltransferase 1, choline, beta	X	-24486125, -24486125	AI857508	9468	Xp22.11	Hs.660708	9	choline-phosphate cytidylyltransferase activity cytoplasm endoplasmic reticulum phosphatidylcholine biosynthetic process phospholipid biosynthetic process biosynthetic process transferase activity nucleotidyltransferase activity	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
224160_s_at	-0.416	6.763	-2.946	9.891e-03	0.166	-2.712	ACAD9	acyl-Coenzyme A dehydrogenase family, member 9	3	130081022	BC001817	28976	3q21.3	Hs.567482	12	acyl-CoA dehydrogenase activity mitochondrion electron carrier activity FAD binding oxidation reduction	Geraniol degradation 1- and 2-Methylnaphthalene degradation
225155_at	-0.879	11.077	-2.946	9.894e-03	0.166	-2.713	SNHG5	small nucleolar RNA host gene 5 (non-protein coding)	6	-86443443	BG339050	387066	6q14.3	Hs.292457	2
241705_at	-0.566	4.263	-2.946	9.896e-03	0.166	-2.713	ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5	17	-64752170, -64752170	AI568925	23461	17q24.3	Hs.421474	11	nucleotide binding ATP binding lysosome endosome Golgi apparatus transport membrane integral to membrane ATPase activity	ABC transporters
201437_s_at	-0.375	7.349	-2.946	9.902e-03	0.166	-2.713	EIF4E	eukaryotic translation initiation factor 4E	4	-100018629, -100018629	NM_001968	1977	4q21-q25	Hs.249718	143	RNA cap binding translation initiation factor activity protein binding cytoplasm cytosol translational initiation regulation of translation eukaryotic translation initiation factor 4F complex interspecies interaction between organisms	mTOR signaling pathway Insulin signaling pathway
218129_s_at	-0.540	6.516	-2.946	9.903e-03	0.166	-2.713	NFYB	nuclear transcription factor Y, beta	12	-103034987	NM_006166	4801	12q22-q23	Hs.84928	38	transcription factor activity protein binding intracellular nucleus CCAAT-binding factor complex sequence-specific DNA binding positive regulation of transcription, DNA-dependent	Antigen processing and presentation
211742_s_at	0.280	4.255	2.945	9.923e-03	0.166	-2.715	EVI2B	ecotropic viral integration site 2B	17	-26654913	BC005926	2124	17q11.2	Hs.5509	10	cytoplasm integral to plasma membrane membrane
218231_at	0.310	7.639	2.944	9.931e-03	0.166	-2.716	NAGK	N-acetylglucosamine kinase	2	71148915	NM_017567	55577	2p13.3	Hs.7036	17	nucleotide binding protein binding ATP binding soluble fraction N-acetylglucosamine metabolic process N-acetylmannosamine metabolic process N-acylmannosamine kinase activity kinase activity transferase activity N-acetylglucosamine kinase activity	Amino sugar and nucleotide sugar metabolism
1555688_s_at	0.308	5.021	2.944	9.941e-03	0.166	-2.717	SLA2	Src-like-adaptor 2	20	-34674335	AF290986	84174	20q11.23	Hs.713578	8	negative regulation of transcription from RNA polymerase II promoter SH3/SH2 adaptor activity cytoplasm plasma membrane endosome membrane B cell mediated immunity intracellular receptor-mediated signaling pathway cytoplasmic vesicle T cell activation protein N-terminus binding regulation of immune response negative regulation of calcium-mediated signaling antigen receptor-mediated signaling pathway negative regulation of B cell activation
1560648_s_at	-0.706	5.408	-2.943	9.950e-03	0.166	-2.718	TSPYL1	TSPY-like 1	6	-116704438	AI625538	7259	6q22-q23	Hs.458358 Hs.486292	11	molecular_function cellular_component intracellular nucleus nucleolus nucleosome assembly biological_process
206197_at	0.402	4.221	2.943	9.952e-03	0.166	-2.718	NME5	non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)	5	-137478759	NM_003551	8382	5q31	Hs.715767	7	nucleoside diphosphate kinase activity protein binding ATP binding cellular_component GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process anti-apoptosis multicellular organismal development spermatid development nucleoside metabolic process
231954_at	0.262	4.190	2.943	9.953e-03	0.166	-2.718	DKFZP434I0714	hypothetical protein DKFZP434I0714	4		AL137273	54553	4q31.23	Hs.142307	1
1556351_at	-0.737	3.388	-2.942	9.971e-03	0.166	-2.720	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	5	-45295108	BM682352	348980	5p12	Hs.650434	17	nucleotide binding voltage-gated ion channel activity voltage-gated potassium channel activity sodium channel activity protein binding ion transport potassium ion transport sodium ion transport membrane integral to membrane axon dendrite cAMP binding potassium ion binding sodium ion binding apical protein localization
211665_s_at	-0.774	5.476	-2.942	9.971e-03	0.166	-2.720	SOS2	son of sevenless homolog 2 (Drosophila)	14	-49653595	L20686	6655	14q21	Hs.291533	20	DNA binding Rho guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular regulation of Rho protein signal transduction regulation of small GTPase mediated signal transduction	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
226170_at	-0.214	7.317	-2.942	9.975e-03	0.166	-2.720	EYA3	eyes absent homolog 3 (Drosophila)	1	-28173405	AA151838	2140	1p36	Hs.185774	9	magnesium ion binding protein tyrosine phosphatase activity protein binding nucleus cytoplasm double-strand break repair response to DNA damage stimulus multicellular organismal development visual perception metabolic process anatomical structure morphogenesis response to ionizing radiation chromatin modification histone dephosphorylation hydrolase activity regulation of transcription positive regulation of DNA repair
211367_s_at	0.337	3.300	2.942	9.975e-03	0.166	-2.720	CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	11	-104401446	U13699	834	11q23	Hs.2490	134	cysteine-type endopeptidase activity protein binding intracellular cytoplasm proteolysis signal transduction peptidase activity caspase activator activity regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade	Amyotrophic lateral sclerosis (ALS)
225477_s_at	-0.369	7.335	-2.942	9.976e-03	0.166	-2.720	NR2C2	nuclear receptor subfamily 2, group C, member 2	3	14964239	AL138444	7182	3p25	Hs.555973	22	transcription factor activity steroid hormone receptor activity transcription coactivator activity nucleus nucleolus regulation of transcription, DNA-dependent nervous system development zinc ion binding sequence-specific DNA binding metal ion binding spermatocyte division
212382_at	0.704	7.361	2.942	9.979e-03	0.166	-2.720	TCF4	transcription factor 4	18	-51040559	BF433429	6925	18q21.1	Hs.605153	55	transcription factor activity protein binding nucleus regulation of transcription positive regulation of transcription, DNA-dependent protein heterodimerization activity
223544_at	0.310	4.705	2.942	9.981e-03	0.166	-2.721	TMEM79	transmembrane protein 79	1	154519327, 154520693	BC005094	84283	1q22	Hs.347408	6	membrane integral to membrane
230025_at	0.323	5.927	2.942	9.982e-03	0.166	-2.721	GJD3	gap junction protein, delta 3, 31.9kDa	17	-35770430	BF508941	125111	17q21.2	Hs.444663	8	protein binding plasma membrane integral to plasma membrane connexon complex cell communication cell surface gap junction assembly cell junction
213231_at	0.231	4.142	2.942	9.982e-03	0.166	-2.721	DMWD	dystrophia myotonica, WD repeat containing	19	-50978103	L19267	1762	19q13.3	Hs.515474	13	molecular_function cellular_component meiosis
202202_s_at	0.704	6.238	2.942	9.982e-03	0.166	-2.721	LAMA4	laminin, alpha 4	6	-112681678, -112535826	NM_002290	3910	6q21	Hs.654572	32	receptor binding extracellular matrix structural constituent extracellular region basal lamina laminin-1 complex regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
223257_at	-0.476	4.248	-2.942	9.983e-03	0.166	-2.721	G2E3	G2/M-phase specific E3 ubiquitin ligase	14	30098079	AI823905	55632	14q12	Hs.509008 Hs.605081	13	protein polyubiquitination blastocyst development ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm Golgi apparatus protein modification process multicellular organismal development zinc ion binding ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process negative regulation of apoptosis metal ion binding
1554892_a_at	0.267	3.218	2.941	9.992e-03	0.166	-2.722	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	11	59580676	AY095480	932	11q12.1	Hs.99960	7	receptor activity protein binding cytoplasm signal transduction membrane integral to membrane perinuclear region of cytoplasm
215992_s_at	-0.305	4.153	-2.941	9.992e-03	0.166	-2.722	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	4	160408447	AL117397	9693	4q32.1	Hs.113912	14	MAPKKK cascade signal transducer activity guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular plasma membrane integral to plasma membrane Rap guanyl-nucleotide exchange factor activity cAMP-mediated signaling diacylglycerol binding Rap GTPase activator activity regulation of small GTPase mediated signal transduction	MAPK signaling pathway
221845_s_at	0.463	5.878	2.941	9.994e-03	0.166	-2.722	CLPB	ClpB caseinolytic peptidase B homolog (E. coli)	11	-71681117	AI655698	81570	11q13.4	Hs.523877	9	nucleotide binding molecular_function ATP binding cellular_component nucleoside-triphosphatase activity cellular response to heat
211597_s_at	0.416	7.451	2.941	1.001e-02	0.166	-2.723	HOPX	HOP homeobox	4	-57208910, -57208910	AB059408	84525	4q11-q12	Hs.654864	25	negative regulation of transcription from RNA polymerase II promoter trophectodermal cell differentiation transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development heart development regulation of heart contraction transcription repressor activity histone deacetylation positive regulation of skeletal muscle regeneration sequence-specific DNA binding negative regulation of cell differentiation lung alveolus development positive regulation of striated muscle cell differentiation
219924_s_at	0.400	5.930	2.940	1.001e-02	0.166	-2.723	ZMYM6	zinc finger, MYM-type 6	1	-35224353	NM_007167	9204	1p34.2	Hs.533986 Hs.623978 Hs.675613	8	DNA binding nucleus nucleolus multicellular organismal development zinc ion binding metal ion binding
227291_s_at	0.492	10.617	2.940	1.001e-02	0.166	-2.723	BOLA3	bolA homolog 3 (E. coli)	2	-74216035	AI380704	388962	2p13.1	Hs.61472	4	molecular_function cellular_component biological_process
231780_at	0.232	5.241	2.940	1.002e-02	0.166	-2.724	GBGT1	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	9	-135018160	AI627912	26301	9q34.13-q34.3	Hs.495419	8	Golgi apparatus carbohydrate metabolic process glycolipid biosynthetic process membrane integral to membrane transferase activity, transferring hexosyl groups manganese ion binding metal ion binding	Glycosphingolipid biosynthesis - globo series Metabolic pathways
209677_at	-0.487	3.387	-2.940	1.002e-02	0.166	-2.724	PRKCI	protein kinase C, iota	3	171422913	L18964	5584	3q26.3	Hs.478199	91	polarisome nucleotide binding protein kinase C activity protein binding ATP binding phospholipid binding nucleus cytoplasm endosome cytosol protein amino acid phosphorylation protein targeting to membrane cytoskeleton organization actin filament organization intracellular signaling cascade zinc ion binding membrane membrane organization vesicle-mediated transport apical plasma membrane transferase activity diacylglycerol binding cellular response to insulin stimulus establishment of apical/basal cell polarity eye photoreceptor cell development establishment or maintenance of epithelial cell apical/basal polarity cell-cell junction organization positive regulation of glucose import metal ion binding secretion Golgi vesicle budding regulation of establishment of protein localization	Endocytosis Tight junction Insulin signaling pathway
224252_s_at	0.289	5.741	2.940	1.002e-02	0.166	-2.724	FXYD5	FXYD domain containing ion transport regulator 5	19	40337466	AF177940	53827	19q12-q13.1	Hs.333418	20	actin binding ion channel activity ion transport membrane integral to membrane microvillus assembly cadherin binding negative regulation of calcium-dependent cell-cell adhesion
207925_at	0.284	4.562	2.940	1.002e-02	0.166	-2.724	CST5	cystatin D	20	-23804571	NM_001900	1473	20p11.21	Hs.121489	16	cysteine-type endopeptidase inhibitor activity protein binding extracellular region peptidase inhibitor activity
202763_at	-0.424	5.490	-2.940	1.002e-02	0.166	-2.725	CASP3	caspase 3, apoptosis-related cysteine peptidase	4	-185785843	NM_004346	836	4q34	Hs.141125	552	B cell homeostasis release of cytochrome c from mitochondria cysteine-type endopeptidase activity cyclin-dependent protein kinase inhibitor activity protein binding nucleus nucleoplasm nucleolus cytoplasm mitochondrion cytosol cytosol plasma membrane DNA fragmentation involved in apoptosis proteolysis response to DNA damage stimulus heart development sensory perception of sound peptidase activity induction of apoptosis via death domain receptors induction of apoptosis by oxidative stress response to UV response to wounding keratinocyte differentiation nuclear fragmentation during apoptosis negative regulation of B cell proliferation response to tumor necrosis factor T cell homeostasis negative regulation of apoptosis cell fate commitment negative regulation of cyclin-dependent protein kinase activity negative regulation of activated T cell proliferation neuron apoptosis	MAPK signaling pathway p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Parkinson's disease Amyotrophic lateral sclerosis (ALS) Huntington's disease Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer
210113_s_at	0.287	5.246	2.939	1.003e-02	0.166	-2.725	NLRP1	NLR family, pyrin domain containing 1	17	-5358161, -5345442	AF310105	22861	17p13.2	Hs.652273	31	nucleotide binding ATP binding intracellular nucleus cytoplasm induction of apoptosis activation of caspase activity defense response caspase activator activity enzyme binding protein domain specific binding regulation of apoptosis neuron apoptosis
202443_x_at	0.374	7.230	2.939	1.003e-02	0.166	-2.725	NOTCH2	Notch homolog 2 (Drosophila)	1	-120255698	AA291203	4853	1p13-p11	Hs.487360	73	cell fate determination ligand-regulated transcription factor activity receptor activity calcium ion binding protein binding protein binding nucleus plasma membrane integral to plasma membrane regulation of transcription, DNA-dependent anti-apoptosis induction of apoptosis cell cycle arrest Notch signaling pathway multicellular organismal development nervous system development negative regulation of cell proliferation organ morphogenesis cell surface cell growth stem cell maintenance hemopoiesis cell differentiation positive regulation of Ras protein signal transduction protein heterodimerization activity regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
222291_at	0.423	4.141	2.939	1.003e-02	0.166	-2.725	FAM149A	family with sequence similarity 149, member A	4	187302988, 187307320	AI478795	25854	4q35.1	Hs.357025	3
209452_s_at	0.334	8.936	2.939	1.004e-02	0.166	-2.726	VTI1B	vesicle transport through interaction with t-SNAREs homolog 1B (yeast)	14	-67187618	AF035824	10490	14q24.1	Hs.226007	18	protein binding Golgi apparatus intracellular protein transport vesicle docking during exocytosis membrane fusion cell proliferation membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
223195_s_at	0.787	6.402	2.939	1.004e-02	0.166	-2.726	SESN2	sestrin 2	1	28458592	BF131886	83667	1p35.3	Hs.469543	8	nucleus cytoplasm cell cycle arrest	p53 signaling pathway
208430_s_at	-0.831	6.117	-2.939	1.004e-02	0.166	-2.726	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	NM_001390	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
203632_s_at	-0.303	7.897	-2.938	1.006e-02	0.166	-2.727	GPRC5B	G protein-coupled receptor, family C, group 5, member B	16	-19777793	NM_016235	51704	16p12	Hs.148685	8	receptor activity G-protein coupled receptor activity nucleus plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane cytoplasmic vesicle
204971_at	1.035	3.603	2.938	1.006e-02	0.166	-2.728	CSTA	cystatin A (stefin A)	3	123526700	NM_005213	1475	3q21	Hs.518198	45	cornified envelope protease binding cysteine-type endopeptidase inhibitor activity structural molecule activity intracellular nucleus cytoplasm negative regulation of peptidase activity peptide cross-linking keratinocyte differentiation protein binding, bridging
239937_at	-0.407	5.690	-2.935	1.012e-02	0.167	-2.734	ZNF207	zinc finger protein 207	17	27701269	AI860558	7756	17q11.2	Hs.500775	7	transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201709_s_at	0.300	5.956	2.935	1.013e-02	0.167	-2.734	NIPSNAP1	nipsnap homolog 1 (C. elegans)	22	-28280797	NM_003634	8508	22q12.2	Hs.173878	9	mitochondrion mitochondrial inner membrane
222156_x_at	-0.447	6.792	-2.935	1.013e-02	0.167	-2.734	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AK022459	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
223421_at	0.249	6.727	2.935	1.013e-02	0.167	-2.734	CYHR1	cysteine/histidine-rich 1	8	-145660007, -145660007, -145646122	BC005073	50626	8q24.3	Hs.459379 Hs.598583	5	protein binding nuclear envelope cytoplasm zinc ion binding metal ion binding perinuclear region of cytoplasm
211330_s_at	0.267	4.123	2.934	1.013e-02	0.167	-2.735	HFE	hemochromatosis	6	26195487	AF144242	3077	6p21.3	Hs.233325	592	antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome
222984_at	-0.258	10.826	-2.934	1.014e-02	0.167	-2.735	PAIP2	poly(A) binding protein interacting protein 2	5	138705417, 138706032	AF151052	51247	5q31.2	Hs.396644	16	protein binding cytoplasm regulation of translation translation repressor activity negative regulation of translational initiation
215082_at	0.310	5.535	2.934	1.014e-02	0.167	-2.735	ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)	6	-53240154	BF973387	60481	6p21.1-p12.1	Hs.713560	11	endoplasmic reticulum fatty acid biosynthetic process membrane integral to membrane	Biosynthesis of unsaturated fatty acids
226154_at	0.368	9.790	2.934	1.015e-02	0.167	-2.736	DNM1L	dynamin 1-like	12	32723403	AL043631	10059	12p11.21	Hs.556296	34	nucleotide binding GTPase activity protein binding GTP binding cytoplasm endoplasmic reticulum cis-Golgi network cytosol mitochondrial membrane organization cell communication multicellular organismal development membrane hydrolase activity mitochondrial fragmentation during apoptosis	Endocytosis Fc gamma R-mediated phagocytosis
203836_s_at	0.499	6.368	2.934	1.015e-02	0.167	-2.736	MAP3K5	mitogen-activated protein kinase kinase kinase 5	6	-136919879	D84476	4217	6q22.33	Hs.186486	108	MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding protein amino acid phosphorylation apoptosis activation of JUN kinase activity induction of apoptosis by extracellular signals caspase activator activity transferase activity protein homodimerization activity interspecies interaction between organisms	MAPK signaling pathway Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS)
219971_at	0.241	4.230	2.933	1.016e-02	0.167	-2.737	IL21R	interleukin 21 receptor	16	27321223, 27321923, 27346079	NM_021798	50615	16p11	Hs.210546	21	interleukin-21 receptor activity receptor activity membrane integral to membrane natural killer cell activation	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
63009_at	0.237	6.412	2.933	1.016e-02	0.167	-2.737	SHQ1	SHQ1 homolog (S. cerevisiae)	3	-72881117	AI188402	55164	3p13	Hs.606584	2
229603_at	0.522	3.196	2.933	1.016e-02	0.167	-2.737	BBS12	Bardet-Biedl syndrome 12	4	123873306	AA971753	166379	4q27	Hs.400698	4	protein binding ATP binding cellular protein metabolic process
226552_at	0.300	5.733	2.933	1.016e-02	0.167	-2.737	IER5L	immediate early response 5-like	9	-130977651	BF110608	389792	9q34.11	Hs.529857	4
228384_s_at	0.742	5.810	2.933	1.016e-02	0.167	-2.737	PYROXD2	pyridine nucleotide-disulphide oxidoreductase domain 2	10	-100133312	AI690274	84795	10q24.2	Hs.238303 Hs.676105	6	oxidoreductase activity oxidation reduction
217071_s_at	0.255	5.981	2.933	1.017e-02	0.167	-2.738	MTHFR	5,10-methylenetetrahydrofolate reductase (NADPH)	1	-11768373	AJ249275	4524	1p36.3	Hs.214142	1776	methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction	One carbon pool by folate Methane metabolism Metabolic pathways
213151_s_at	-0.321	9.516	-2.933	1.017e-02	0.167	-2.738	SEPT7	septin 7	7	35807151	AU157515	989	7p14.3-p14.1	Hs.191346 Hs.642540	23	nucleotide binding condensed chromosome kinetochore cytokinesis stress fiber structural molecule activity protein binding GTP binding nucleus cytoplasm spindle cell cycle mitosis septin complex protein heterooligomerization
211250_s_at	0.252	5.775	2.933	1.017e-02	0.167	-2.738	SH3BP2	SH3-domain binding protein 2	4	2764547, 2783743, 2789709, 2790338	AB000463	6452	4p16.3	Hs.167679	34	SH3/SH2 adaptor activity protein binding signal transduction SH3 domain binding	Natural killer cell mediated cytotoxicity
222484_s_at	0.723	8.550	2.932	1.019e-02	0.167	-2.739	CXCL14	chemokine (C-X-C motif) ligand 14	5	-134934267	AF144103	9547	5q31	Hs.483444	32	extracellular region extracellular space Golgi apparatus chemotaxis immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
1555266_a_at	0.258	4.036	2.932	1.019e-02	0.167	-2.739	ASXL2	additional sex combs like 2 (Drosophila)	2	-25815756	BC042999	55252	2p24.1	Hs.594386	6	nucleus zinc ion binding regulation of transcription metal ion binding
221787_at	-0.479	6.883	-2.931	1.019e-02	0.167	-2.740	C6orf120	chromosome 6 open reading frame 120	6	169844181	BF431618	387263	6q27	Hs.591375 Hs.694601	4	extracellular region
229594_at	-0.361	6.287	-2.931	1.020e-02	0.167	-2.740	SPTY2D1	SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)	11	-18584523	AI890299	144108	11p15.1	Hs.268668 Hs.719399	2
218124_at	0.491	7.112	2.931	1.020e-02	0.167	-2.741	RETSAT	retinol saturase (all-trans-retinol 13,14-reductase)	2	-85422589	NM_017750	54884	2p11.2	Hs.440401	11	nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane electron carrier activity membrane oxidoreductase activity retinol metabolic process all-trans-retinol 13,14-reductase activity oxidation reduction	Retinol metabolism
201489_at	0.481	9.307	2.931	1.020e-02	0.167	-2.741	PPIF	peptidylprolyl isomerase F	10	80777225	BC005020	10105	10q22-q23	Hs.381072	13	peptidyl-prolyl cis-trans isomerase activity membrane fraction mitochondrion mitochondrial matrix protein folding isomerase activity peptide binding
217810_x_at	-0.324	8.383	-2.931	1.021e-02	0.167	-2.742	LARS	leucyl-tRNA synthetase	5	-145472781	NM_020117	51520	5q32	Hs.432674	20	nucleotide binding leucine-tRNA ligase activity ATP binding cytoplasm leucyl-tRNA aminoacylation ligase activity	Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis
217595_at	-0.263	2.713	-2.930	1.023e-02	0.168	-2.743	GSPT1	G1 to S phase transition 1	16	-11869485, -11869485	AV701723	2935	16p13.1	Hs.528780	27	G1/S transition of mitotic cell cycle nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translation release factor activity GTPase activity protein binding GTP binding intracellular translation protein amino acid methylation
209340_at	-0.558	8.112	-2.929	1.025e-02	0.168	-2.745	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	1	160797919	S73498	6675	1q23.3	Hs.492859	10	UDP-N-acetylglucosamine diphosphorylase activity nucleus nucleolus cytoplasm UDP-N-acetylglucosamine biosynthetic process metabolic process transferase activity nucleotidyltransferase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
230612_at	0.294	4.758	2.929	1.025e-02	0.168	-2.745	WDR73	WD repeat domain 73	15	-82987014	AI264119	84942	15q25.2	Hs.719288	3
217594_at	-0.404	3.949	-2.928	1.027e-02	0.168	-2.747	ZCCHC11	zinc finger, CCHC domain containing 11	1	-52661535	R25849	23318	1p32.3	Hs.655407	7	nucleic acid binding protein binding intracellular nucleus cytoplasm zinc ion binding nucleotidyltransferase activity metal ion binding
211767_at	0.250	4.446	2.927	1.028e-02	0.168	-2.748	GINS4	GINS complex subunit 4 (Sld5 homolog)	8	41505881	BC005995	84296	8p11.21	Hs.656996	4	protein binding nucleus cytoplasm DNA replication
217548_at	0.274	4.497	2.927	1.029e-02	0.168	-2.749	LOC100129502	hypothetical protein LOC100129502	15		AA491625	100129502	15q26.1	Hs.709285	1
219017_at	0.448	4.987	2.927	1.030e-02	0.168	-2.749	ETNK1	ethanolamine kinase 1	12	22669342, 22669342	NM_018638	55500	12p12.1	Hs.29464	4	nucleotide binding ethanolamine kinase activity ATP binding cytoplasm phosphatidylethanolamine biosynthetic process transferase activity	Glycerophospholipid metabolism Metabolic pathways
1561985_at	-0.590	4.564	-2.927	1.030e-02	0.168	-2.749	C14orf39	chromosome 14 open reading frame 39	14	-59972426	AL832219	317761	14q23.1	Hs.335754	3	molecular_function cellular_component multicellular organismal development regulation of transcription factor activity
224823_at	1.003	7.388	2.926	1.031e-02	0.168	-2.750	MYLK	myosin light chain kinase	3	-124813832, -124813832	AA526844	4638	3q21	Hs.477375	56	nucleotide binding magnesium ion binding actin binding myosin light chain kinase activity calcium ion binding calmodulin binding ATP binding protein amino acid phosphorylation transferase activity	Calcium signaling pathway Vascular smooth muscle contraction Focal adhesion Regulation of actin cytoskeleton
1565716_at	0.408	5.339	2.926	1.031e-02	0.168	-2.750	FUS	fusion (involved in t(12;16) in malignant liposarcoma)	16	31098953	BE930017	2521	16p11.2	Hs.513522	55	nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding intracellular nucleus nucleolus cell death zinc ion binding metal ion binding
212622_at	-0.418	7.450	-2.926	1.031e-02	0.168	-2.751	TMEM41B	transmembrane protein 41B	11	-9258777	N64760	440026	11p15.4	Hs.594563	4	membrane integral to membrane
227396_at	0.579	5.515	2.926	1.032e-02	0.168	-2.751	PTPRJ	protein tyrosine phosphatase, receptor type, J	11	47958685, 47958685	AI631833	5795	11p11.2	Hs.318547	36	transmembrane receptor protein tyrosine phosphatase activity protein binding nucleus plasma membrane integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling hydrolase activity cell junction	Adherens junction
225057_at	-0.436	7.770	-2.925	1.033e-02	0.169	-2.752	SLC15A4	solute carrier family 15, member 4	12	-127843692	AI636759	121260	12q24.32-q24.33	Hs.507260 Hs.699387	6	transporter activity oligopeptide transport protein transport symporter activity membrane integral to membrane
203332_s_at	0.261	5.726	2.924	1.035e-02	0.169	-2.754	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	2	233633279	NM_005541	3635	2q37.1	Hs.262886 Hs.601911	57	inositol or phosphatidylinositol phosphatase activity inositol-polyphosphate 5-phosphatase activity protein binding cytoplasm cytosol phosphate metabolic process apoptosis immune response signal transduction membrane hydrolase activity SH3 domain binding	Phosphatidylinositol signaling system B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway
1556573_s_at	-0.229	4.715	-2.924	1.036e-02	0.169	-2.755	LOC286178	hypothetical protein LOC286178	8		AK090741	286178	8q12.1	Hs.255156	1
207243_s_at	-0.475	11.436	-2.924	1.036e-02	0.169	-2.755	CALM2	calmodulin 2 (phosphorylase kinase, delta)	2	-47240725	NM_001743	805	2p21	Hs.468442	52		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
1553371_at	0.281	4.020	2.924	1.036e-02	0.169	-2.755	EPHA10	EPH receptor A10	1	-37998531, -37954232	NM_173641	284656	1p34.3	Hs.129435	5	nucleotide binding receptor activity ephrin receptor activity ATP binding extracellular region plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane transferase activity
204927_at	0.186	6.532	2.923	1.037e-02	0.169	-2.755	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	11	550970, 551449	NM_003475	8045	11p15.5	Hs.72925	9	DNA binding protein binding nucleus regulation of transcription, DNA-dependent signal transduction
210878_s_at	-0.380	8.178	-2.923	1.037e-02	0.169	-2.756	KDM3B	lysine (K)-specific demethylase 3B	5	137716183	BC001202	51780	5q31	Hs.714832	14	iron ion binding nucleus nucleolus zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
230925_at	0.488	4.932	2.922	1.039e-02	0.169	-2.757	APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	10	26767271	AI093231	54518	10p12.1	Hs.310421	9	cytoplasm cytoskeleton plasma membrane focal adhesion signal transduction lamellipodium cell junction
224483_s_at	0.244	3.129	2.922	1.039e-02	0.169	-2.758	MFSD9	major facilitator superfamily domain containing 9	2	-102700097	BC006242	84804	2q12.1	Hs.590898	3	transport tetracycline:hydrogen antiporter activity tetracycline transport membrane integral to membrane response to antibiotic
224827_at	-0.480	6.243	-2.922	1.040e-02	0.169	-2.759	UBTD2	ubiquitin domain containing 2	5	-171569254	AK022894	92181	5q35.1	Hs.131570 Hs.716824	7	cytoplasm
204974_at	0.374	5.940	2.921	1.041e-02	0.169	-2.759	RAB3A	RAB3A, member RAS oncogene family	19	-18168610	AA988241	5864	19p13.2	Hs.27744	46	nucleotide binding respiratory system process GTPase activity protein binding protein binding GTP binding plasma membrane mitochondrion organization small GTPase mediated signal transduction neuromuscular synaptic transmission axonogenesis synaptic vesicle post-embryonic development protein transport synaptic vesicle exocytosis synaptic vesicle maturation lung development regulation of synaptic vesicle fusion to presynaptic membrane maintenance of presynaptic active zone structure sensory perception of touch response to electrical stimulus
227622_at	0.517	8.053	2.921	1.041e-02	0.169	-2.759	PCF11	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	11	82545784	AW118175	51585	11q13	Hs.128959	10	nuclear mRNA splicing, via spliceosome nucleus mRNA cleavage factor complex mRNA cleavage
214711_at	-0.549	4.818	-2.921	1.041e-02	0.169	-2.759	GATC	glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial)	12	119368666	BE568184	283459	12q24.31	Hs.369624	4	molecular_function cellular_component regulation of translational fidelity biological_process
229877_at	0.224	2.554	2.921	1.042e-02	0.169	-2.760	NEO1	neogenin homolog 1 (chicken)	15	71131927	BF058828	4756	15q22.3-q23	Hs.388613	17	protein binding plasma membrane integral to plasma membrane cell adhesion	Cell adhesion molecules (CAMs)
210705_s_at	0.354	4.298	2.920	1.043e-02	0.169	-2.761	TRIM5	tripartite motif-containing 5	11	-5642928, -5641368, -5641363	AF220028	85363	11p15	Hs.370515	55	cytoplasmic mRNA processing body protein binding intracellular cytoplasm zinc ion binding response to virus ligase activity modification-dependent protein catabolic process protein homodimerization activity interspecies interaction between organisms metal ion binding
226493_at	-0.555	6.780	-2.919	1.045e-02	0.169	-2.763	KCTD18	potassium channel tetramerisation domain containing 18	2	-201061928	AI627249	130535	2q33.1	Hs.605775	4	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
209379_s_at	-0.461	8.617	-2.919	1.045e-02	0.169	-2.763	FAM190B	family with sequence similarity 190, member B	10	86078389	AF241785	54462	10q23.1	Hs.461988	5
210154_at	0.548	6.228	2.919	1.045e-02	0.169	-2.763	ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	18	46659432	M55905	4200	18q21 6p25-p24	Hs.233119	24	malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide
1561504_s_at	-2.326	7.634	-2.919	1.046e-02	0.169	-2.763	MYLK4	myosin light chain kinase family, member 4	6	-2608861	AK096893	340156	6p25.2	Hs.127830	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
235114_x_at	-0.402	3.985	-2.919	1.047e-02	0.169	-2.764	HOOK3	hook homolog 3 (Drosophila)	8	42871189	N67300	84376	8p11.21	Hs.162852	13	cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex
202588_at	-0.324	8.800	-2.918	1.047e-02	0.169	-2.764	AK1	adenylate kinase 1	9	-129668579	NM_000476	203	9q34.1	Hs.175473	24	nucleotide binding adenylate kinase activity protein binding ATP binding nucleus cytoplasm mitochondrion cytosol plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle arrest transferase activity nucleoside kinase activity ATP metabolic process	Purine metabolism Metabolic pathways
224195_at	-0.366	3.202	-2.918	1.048e-02	0.170	-2.765	TTTY12	testis-specific transcript, Y-linked 12 (non-protein coding)	Y	7732964	AF332241	83867	Yp11.2	Hs.667616	1
37145_at	0.444	4.501	2.918	1.048e-02	0.170	-2.765	GNLY	granulysin	2	85774924	M85276	10578	2p11.2	Hs.105806	36	extracellular region extracellular space xenobiotic metabolic process cellular defense response defense response to bacterium defense response to fungus
230493_at	-1.197	6.598	-2.918	1.049e-02	0.170	-2.766	SHISA2	shisa homolog 2 (Xenopus laevis)	13	-25516734	AW664964	387914	13q12.13	Hs.433791	4	endoplasmic reticulum multicellular organismal development membrane integral to membrane
227569_at	-0.413	6.493	-2.918	1.049e-02	0.170	-2.766	LNX2	ligand of numb-protein X 2	13	-27018049	AU151331	222484	13q12.2	Hs.132359	6	protein binding zinc ion binding PDZ domain binding metal ion binding protein homooligomerization
225070_at	-0.331	5.704	-2.917	1.049e-02	0.170	-2.766	NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	6	118103309	BF112132	116150	6q22.1	Hs.289008	6	angiogenesis molecular_function receptor activity cellular_component multicellular organismal development biological_process membrane integral to membrane transferase activity, transferring alkyl or aryl (other than methyl) groups cell differentiation
219778_at	-0.703	7.658	-2.917	1.051e-02	0.170	-2.767	ZFPM2	zinc finger protein, multitype 2	8	106400322	NM_012082	23414	8q23	Hs.431009	16	negative regulation of transcription from RNA polymerase II promoter vasculogenesis in utero embryonic development DNA binding RNA polymerase II transcription factor activity transcription corepressor activity intracellular nucleus cytoplasm transcription factor binding zinc ion binding lung development regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding embryonic organ development cardiac muscle tissue development
227649_s_at	0.225	5.412	2.917	1.051e-02	0.170	-2.768	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	1	204582822, 204582822	AU144000	23380	1q32.1	Hs.497575	7	GTPase activator activity intracellular signal transduction	Axon guidance
203412_at	0.279	6.218	2.917	1.051e-02	0.170	-2.768	LZTR1	leucine-zipper-like transcription regulator 1	22	19666557	NM_006767	8216	22q11.1-q11.2 22q11.21	Hs.78788	10	transcription factor activity protein binding anatomical structure morphogenesis
218970_s_at	-0.443	10.917	-2.916	1.052e-02	0.170	-2.769	CUTC	cutC copper transporter homolog (E. coli)	10	101481947	NM_015960	51076	10q24.2	Hs.16606	10	copper ion binding nucleus cytoplasm copper ion transport copper ion homeostasis
220952_s_at	0.542	4.968	2.916	1.053e-02	0.170	-2.770	PLEKHA5	pleckstrin homology domain containing, family A member 5	12	19173914, 19173914, 19249525	NM_019012	54477	12p12	Hs.188614	13	protein binding phosphatidylinositol binding cellular_component biological_process
244115_at	-0.339	3.724	-2.915	1.053e-02	0.170	-2.770	FAM126A	family with sequence similarity 126, member A	7	-22947402	AA608855	84668	7p15.3	Hs.85603	9	signal transducer activity cellular_component cytoplasm biological_process membrane
206685_at	0.246	3.409	2.915	1.054e-02	0.170	-2.770	HCG4	HLA complex group 4	6	-29866787, -1211427, -1013559	NM_018985	54435	6p21.3	Hs.660431	2
213071_at	0.698	7.195	2.915	1.054e-02	0.170	-2.770	DPT	dermatopontin	1	-166931329	AL049798	1805	1q12-q23	Hs.80552	13	protein binding extracellular region proteinaceous extracellular matrix cell adhesion negative regulation of cell proliferation collagen fibril organization
229121_at	0.248	5.331	2.915	1.054e-02	0.170	-2.771	CMKLR1	chemokine-like receptor 1	12	-107205951, -107205951	BE857553	1240	12q24.1	Hs.197143	14	skeletal system development receptor activity G-protein coupled receptor activity chemokine receptor activity plasma membrane integral to plasma membrane chemotaxis immune response signal transduction G-protein coupled receptor protein signaling pathway
203137_at	-0.395	8.932	-2.915	1.054e-02	0.170	-2.771	WTAP	Wilms tumor 1 associated protein	6	160068141, 160068141, 160068609	NM_004906	9589	6q25-q27	Hs.446091 Hs.710715	16	nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane
209488_s_at	0.477	4.861	2.915	1.055e-02	0.170	-2.771	RBPMS	RNA binding protein with multiple splicing	8	30361485, 30361485	D84109	11030	8p12-p11	Hs.334587	8	nucleotide binding RNA binding protein binding RNA processing
213574_s_at	-0.409	8.607	-2.914	1.056e-02	0.170	-2.772	KPNB1	karyopherin (importin) beta 1	17	43082273	AA861608	3837	17q21.32	Hs.532793 Hs.706168	113	protein import into nucleus, docking protein import into nucleus, translocation nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus ribosomal protein import into nucleus nuclear localization sequence binding zinc ion binding protein transporter activity protein domain specific binding interspecies interaction between organisms
208623_s_at	0.898	6.073	2.914	1.056e-02	0.170	-2.773	EZR	ezrin	6	-159106760, -159106760	J05021	7430	6q25.2-q26	Hs.487027	158	ruffle cytoplasm cytosol actin filament plasma membrane microvillus cell cortex cytoskeletal anchoring at plasma membrane leukocyte adhesion cytoskeletal protein binding regulation of cell shape extrinsic to membrane membrane to membrane docking filopodium cortical cytoskeleton apical part of cell cell adhesion molecule binding actin filament binding actin filament bundle formation	Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
204856_at	0.245	5.748	2.913	1.058e-02	0.170	-2.774	B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	19	17766918	NM_014256	10331	19p13.1	Hs.657825 Hs.69009	13	Golgi apparatus integral to plasma membrane protein amino acid glycosylation galactosyltransferase activity membrane transferase activity, transferring glycosyl groups	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
200966_x_at	-0.322	13.385	-2.913	1.059e-02	0.170	-2.774	ALDOA	aldolase A, fructose-bisphosphate	16	29971991, 29983100, 29983473, 29984544	NM_000034	226	16p11.2	Hs.513490	55	actin binding fructose-bisphosphate aldolase activity glycolysis ATP biosynthetic process striated muscle contraction actin filament organization metabolic process regulation of cell shape actin cytoskeleton tubulin binding lyase activity fructose 1,6-bisphosphate metabolic process I band identical protein binding muscle maintenance fructose binding extracellular vesicular exosome	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
209900_s_at	-0.527	8.169	-2.912	1.060e-02	0.170	-2.776	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	AL162079	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
216958_s_at	0.414	6.588	2.912	1.060e-02	0.170	-2.776	IVD	isovaleryl Coenzyme A dehydrogenase	15	38484977	AK022777	3712	15q14-q15	Hs.513646	21	mitochondrion mitochondrial matrix isovaleryl-CoA dehydrogenase activity electron carrier activity FAD binding oxidation reduction	Valine, leucine and isoleucine degradation Metabolic pathways
216713_at	-0.350	6.987	-2.912	1.061e-02	0.170	-2.777	KRIT1	KRIT1, ankyrin repeat containing	7	-91666218, -91666218, -91666218	AL049325	889	7q21-q22	Hs.531987	48	small GTPase regulator activity protein binding cytoskeleton small GTPase mediated signal transduction membrane
239527_at	0.279	2.997	2.911	1.063e-02	0.170	-2.778	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	BF103605	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
202799_at	0.309	8.734	2.911	1.064e-02	0.171	-2.779	CLPP	ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)	19	6312462	NM_006012	8192	19p13.3	Hs.515092	9	nucleotide binding serine-type endopeptidase activity protein binding ATP binding mitochondrion proteolysis peptidase activity
212060_at	-0.634	5.202	-2.911	1.064e-02	0.171	-2.779	SR140	U2-associated SR140 protein	3	144203061	AU152088	23350	3q23	Hs.596572	4	nucleotide binding RNA binding RNA processing
228559_at	-0.356	3.871	-2.910	1.065e-02	0.171	-2.780	CENPN	centromere protein N	16	79597603, 79597603, 79597603	BF111626	55839	16q23.2	Hs.55028	9	chromosome, centromeric region condensed chromosome kinetochore nucleus chromosome
225845_at	-0.485	10.007	-2.910	1.066e-02	0.171	-2.781	ZBTB44	zinc finger and BTB domain containing 44	11	-129601783	BG253884	29068	11q24.3	Hs.719099	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
205932_s_at	0.280	5.757	2.909	1.066e-02	0.171	-2.781	MSX1	msh homeobox 1	4	4912292	NM_002448	4487	4p16.3-p16.1	Hs.424414	53	negative regulation of transcription from RNA polymerase II promoter in utero embryonic development heart morphogenesis transcription factor activity protein binding nucleus multicellular organismal development muscle organ development negative regulation of cell proliferation transcription repressor activity embryonic limb morphogenesis BMP signaling pathway forebrain development midbrain development negative regulation of apoptosis sequence-specific DNA binding cartilage development
225154_at	-0.240	8.403	-2.909	1.067e-02	0.171	-2.782	SYAP1	synapse associated protein 1, SAP47 homolog (Drosophila)	X	16647675	BG029566	94056	Xp22.2	Hs.605178	11	nucleus
229726_at	0.232	5.785	2.909	1.067e-02	0.171	-2.782	GRAP	GRB2-related adaptor protein	17	-18864714	AW007479	10750	17p11.2	Hs.567416	13	SH3/SH2 adaptor activity protein binding cytoplasm Ras protein signal transduction cell-cell signaling
204699_s_at	0.274	4.663	2.909	1.067e-02	0.171	-2.782	C1orf107	chromosome 1 open reading frame 107	1	208067955	N30910	27042	1q32.2	Hs.194754	6	nucleus multicellular organismal development
201534_s_at	-0.436	7.049	-2.909	1.068e-02	0.171	-2.782	UBL3	ubiquitin-like 3	13	-29236545	AF044221	5412	13q12-q13	Hs.145575	12	intracellular plasma membrane
210458_s_at	-0.713	4.705	-2.909	1.068e-02	0.171	-2.782	TANK	TRAF family member-associated NFKB activator	2	161701711, 161701711	BC003388	10010	2q24-q31	Hs.132257	22	protein binding cytoplasm signal transduction zinc ion binding metal ion binding	RIG-I-like receptor signaling pathway
233498_at	-0.754	5.080	-2.909	1.068e-02	0.171	-2.783	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	2	-211948686	AK024204	2066	2q33.3-q34	Hs.390729	112	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway nervous system development heart development cell proliferation membrane integral to membrane basolateral plasma membrane transferase activity cell fate commitment	ErbB signaling pathway Calcium signaling pathway Endocytosis
230430_at	0.201	5.452	2.908	1.069e-02	0.171	-2.783	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	9	-139062373	AW134837	954	9q34	Hs.123036	14	magnesium ion binding calcium ion binding membrane integral to membrane hydrolase activity	Purine metabolism
224314_s_at	-0.501	5.655	-2.908	1.070e-02	0.171	-2.784	EGLN1	egl nine homolog 1 (C. elegans)	1	-229566120	AF277174	54583	1q42.1	Hs.444450 Hs.710300	42	response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
218179_s_at	-0.388	5.932	-2.907	1.071e-02	0.171	-2.785	C4orf41	chromosome 4 open reading frame 41	4	184817439	NM_021942	60684	4q35.1	Hs.443240	6
203533_s_at	-0.434	7.873	-2.907	1.071e-02	0.171	-2.785	CUL5	cullin 5	11	107384617	NM_003478	8065	11q22-q23	Hs.440320 Hs.701122	38	G1/S transition of mitotic cell cycle receptor activity calcium channel activity protein binding cytosol ubiquitin-dependent protein catabolic process cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding interspecies interaction between organisms	Ubiquitin mediated proteolysis
1553364_at	0.235	2.841	2.907	1.071e-02	0.171	-2.785	PNPLA1	patatin-like phospholipase domain containing 1	6	36318922, 36318957, 36346214	NM_173676	285848	6p21.31	Hs.407002	5	metabolic process lipid catabolic process hydrolase activity
208570_at	0.301	3.165	2.907	1.072e-02	0.171	-2.786	WNT1	wingless-type MMTV integration site family, member 1	12	47658502	NM_005430	7471	12q13	Hs.248164	72	cell fate specification signal transducer activity receptor binding extracellular region proteinaceous extracellular matrix establishment or maintenance of cell polarity Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development central nervous system development cell migration diencephalon development forebrain anterior/posterior pattern formation midbrain-hindbrain boundary maturation during brain development cell differentiation inner ear morphogenesis positive regulation of transcription, DNA-dependent neuron fate determination	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
228198_s_at	0.338	6.122	2.906	1.073e-02	0.171	-2.787	LOC729234	fumarylacetoacetate hydrolase domain containing 2 pseudogene	2	96040025	AI271418	729234	2q11.1	Hs.348629	2
213840_s_at	0.225	6.241	2.906	1.073e-02	0.171	-2.787	MRPS12	mitochondrial ribosomal protein S12	19	44113187, 44113433	R68573	6183	19q13.1-q13.2	Hs.411125	15	structural constituent of ribosome protein binding intracellular mitochondrion mitochondrial ribosome ribosome translation small ribosomal subunit
228077_at	0.464	7.456	2.906	1.073e-02	0.171	-2.787	MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)	19	13736336	AK026666	84245	19p13.2	Hs.439370	11	cellular amino acid biosynthetic process methionine biosynthetic process isomerase activity identical protein binding cellular biosynthetic process S-methyl-5-thioribose-1-phosphate isomerase activity
223382_s_at	-0.415	8.410	-2.906	1.073e-02	0.171	-2.787	ZNRF1	zinc and ring finger 1	16	73590415	AL136903	84937	16q23.1	Hs.427284	11	protein binding lysosome endosome zinc ion binding membrane ligase activity modification-dependent protein catabolic process cell junction cytoplasmic vesicle synapse metal ion binding
209077_at	0.269	9.175	2.906	1.074e-02	0.171	-2.788	TXN2	thioredoxin 2	22	-35193038	AL022313	25828	22q13.1	Hs.211929	19	nucleolus cytoplasm mitochondrion glycerol ether metabolic process transport electron carrier activity protein disulfide oxidoreductase activity electron transport chain cell redox homeostasis
212515_s_at	-0.679	8.010	-2.906	1.074e-02	0.171	-2.788	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	X	41077594	BG492602	1654	Xp11.3-p11.23	Hs.719127	34	nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus cytoplasm plasma membrane nuclear speck hydrolase activity interspecies interaction between organisms	RIG-I-like receptor signaling pathway
215418_at	0.297	5.060	2.906	1.074e-02	0.171	-2.788	PARVA	parvin, alpha	11	12355721	AK022316	55742	11p15.3	Hs.607144	17	actin binding protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion lamellipodium cell junction	Focal adhesion
1554468_s_at	0.246	6.161	2.906	1.074e-02	0.171	-2.788	FBF1	Fas (TNFRSF6) binding factor 1	17	-71418212	AU143610	85302	17q25.1	Hs.442609	7	cytoplasm
215498_s_at	-0.676	8.537	-2.905	1.076e-02	0.171	-2.790	MAP2K3	mitogen-activated protein kinase kinase 3	17	21128560, 21135373	AA780381	5606	17q11.2	Hs.514012	45	nucleotide binding activation of MAPK activity protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding inflammatory response signal transduction transferase activity regulation of cytokine biosynthetic process positive regulation of protein kinase activity positive regulation of transcription, DNA-dependent cardiac muscle contraction	MAPK signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway GnRH signaling pathway Amyotrophic lateral sclerosis (ALS)
233939_at	0.353	6.084	2.905	1.076e-02	0.171	-2.790	REXO1	REX1, RNA exonuclease 1 homolog (S. cerevisiae)	19	-1766244	AL117522	57455	19p13.3	Hs.192477	6	nucleic acid binding exonuclease activity intracellular nucleus hydrolase activity
222629_at	0.597	5.370	2.905	1.077e-02	0.171	-2.790	REV1	REV1 homolog (S. cerevisiae)	2	-99383369	N51427	51455	2q11.1-q11.2	Hs.443077	27	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication DNA repair response to DNA damage stimulus response to UV transferase activity deoxycytidyl transferase activity error-prone postreplication DNA repair
202007_at	0.454	5.639	2.905	1.077e-02	0.171	-2.790	NID1	nidogen 1	1	-234205754	BF940043	4811	1q43	Hs.356624	39	calcium ion binding protein binding extracellular region basement membrane cell adhesion cell-matrix adhesion bioluminescence membrane protein-chromophore linkage
208629_s_at	0.533	8.764	2.904	1.079e-02	0.171	-2.792	HADHA	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	2	-26267007	BG472176	3030	2p23	Hs.516032	36	acyl-CoA binding 3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity fatty acid beta-oxidation multienzyme complex long-chain-enoyl-CoA hydratase activity long-chain-3-hydroxyacyl-CoA dehydrogenase activity lyase activity response to drug mitochondrial nucleoid NAD or NADH binding oxidation reduction	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Biosynthesis of unsaturated fatty acids Metabolic pathways
206584_at	0.604	3.717	2.904	1.079e-02	0.171	-2.792	LY96	lymphocyte antigen 96	8	75066140	NM_015364	23643	8q21.11	Hs.660766	65	lipopolysaccharide receptor activity protein binding extracellular region extracellular space plasma membrane plasma membrane inflammatory response immune response cellular defense response cell surface receptor linked signal transduction I-kappaB kinase/NF-kappaB cascade coreceptor activity detection of lipopolysaccharide lipopolysaccharide receptor complex	Toll-like receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
203978_at	-0.276	7.047	-2.903	1.079e-02	0.171	-2.792	NUBP1	nucleotide binding protein 1 (MinD homolog, E. coli)	16	10745198	NM_002484	4682	16p13.13	Hs.81469	9	nucleotide binding protein binding ATP binding cytosol cellular iron ion homeostasis cell growth iron-sulfur cluster assembly nucleoside-triphosphatase activity iron-sulfur cluster binding
212306_at	-0.624	7.919	-2.903	1.080e-02	0.171	-2.793	CLASP2	cytoplasmic linker associated protein 2	3	-33512741	AI741784	23122	3p22.3	Hs.108614	17	condensed chromosome kinetochore protein binding cytoplasm Golgi apparatus centrosome spindle kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity galactoside 2-alpha-L-fucosyltransferase activity regulation of microtubule polymerization or depolymerization microtubule plus-end binding cell division
220544_at	0.270	4.192	2.903	1.080e-02	0.171	-2.793	TSKS	testis-specific serine kinase substrate	19	-54934822	NM_021733	60385	19q13.3	Hs.515858	6	protein binding
1552919_at	0.265	2.365	2.903	1.081e-02	0.171	-2.794	C4orf36	chromosome 4 open reading frame 36	4	-88016381	NM_144645	132989	4q21.3	Hs.339646	4
215280_s_at	0.316	5.532	2.902	1.082e-02	0.171	-2.794	PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	19	54314474	AK023850	8541	19q13.33	Hs.413748	8	protein binding cytoplasm cell surface
200832_s_at	2.124	5.195	2.902	1.082e-02	0.171	-2.794	SCD	stearoyl-CoA desaturase (delta-9-desaturase)	10	102096761	AB032261	6319	10q24.31	Hs.558396 Hs.597496	43	stearoyl-CoA 9-desaturase activity iron ion binding endoplasmic reticulum fatty acid biosynthetic process membrane integral to membrane oxidoreductase activity nuclear membrane oxidation reduction	Biosynthesis of unsaturated fatty acids PPAR signaling pathway
210298_x_at	-0.644	11.878	-2.902	1.083e-02	0.171	-2.795	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	AF098518	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
212253_x_at	-0.289	7.883	-2.902	1.083e-02	0.171	-2.795	DST	dystonin	6	-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743	BG253119	667	6p12.1	Hs.631992 Hs.669931	48	actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding
242274_x_at	0.414	4.133	2.902	1.083e-02	0.171	-2.796	SLC25A42	solute carrier family 25, member 42	19	19035807	AI057363	284439	19p13.11	Hs.303669	3	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
224878_at	-0.365	8.142	-2.902	1.084e-02	0.171	-2.796	UBFD1	ubiquitin family domain containing 1	16	23476362	N63936	56061	16p12	Hs.3459	3
223167_s_at	-0.895	8.359	-2.901	1.085e-02	0.172	-2.797	USP25	ubiquitin specific peptidase 25	21	16024366	AF170562	29761	21q11.2	Hs.473370	11	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
35776_at	-0.278	7.459	-2.901	1.085e-02	0.172	-2.797	ITSN1	intersectin 1 (SH3 domain protein)	21	33936653, 33936653	AF064243	6453	21q22.1-q22.2	Hs.160324	39	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular intracellular signaling cascade membrane synaptosome lamellipodium cell junction regulation of Rho protein signal transduction synapse synaptic vesicle endocytosis
208842_s_at	-0.279	7.657	-2.900	1.087e-02	0.172	-2.799	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	W93787	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
225167_at	0.358	4.415	2.900	1.087e-02	0.172	-2.799	FRMD4A	FERM domain containing 4A	10	-13725711	AW515645	55691	10p13	Hs.330463 Hs.656573	3	binding cytoplasm cytoskeleton
213128_s_at	-0.536	8.400	-2.900	1.088e-02	0.172	-2.799	UBE3A	ubiquitin protein ligase E3A	15	-23133488, -23133488, -23133488	AA527499	7337	15q11-q13	Hs.598862	76	ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms	Ubiquitin mediated proteolysis
203588_s_at	-0.423	6.335	-2.900	1.088e-02	0.172	-2.800	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	BG034328	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
203322_at	0.315	6.327	2.899	1.088e-02	0.172	-2.800	ADNP2	ADNP homeobox 2	18	75967902	AU145934	22850	18q23	Hs.131915	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
201749_at	0.228	7.762	2.899	1.088e-02	0.172	-2.800	ECE1	endothelin converting enzyme 1	1	-21416326, -21416326, -21416326, -21416326	BF969352	1889	1p36.1	Hs.195080	63	response to hypoxia positive regulation of receptor recycling regulation of systemic arterial blood pressure by endothelin metalloendopeptidase activity membrane fraction endosome Golgi apparatus plasma membrane proteolysis apoptosis heart development peptidase activity zinc ion binding external side of plasma membrane substance P catabolic process bradykinin catabolic process calcitonin catabolic process integral to membrane peptide hormone binding regulation of vasoconstriction intrinsic to endosome membrane vesicle Weibel-Palade body endothelin maturation embryonic digit morphogenesis protein homodimerization activity ear development positive regulation of G-protein coupled receptor protein signaling pathway metal ion binding perinuclear region of cytoplasm
226559_at	0.236	4.875	2.899	1.089e-02	0.172	-2.800	IER5L	immediate early response 5-like	9	-130977651	AL555612	389792	9q34.11	Hs.529857	4
223370_at	-0.403	6.898	-2.899	1.090e-02	0.172	-2.801	PLEKHA3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	2	179053444	AF286162	65977	2q31.2	Hs.41086	7	phospholipid binding phosphatidylinositol binding cellular_component cytoplasm biological_process membrane
230152_at	-0.393	4.208	-2.899	1.090e-02	0.172	-2.801	WDR52	WD repeat domain 52	3	-114564401	AI346359	55779	3q13.2	Hs.584936	2
226184_at	-0.475	6.725	-2.898	1.091e-02	0.172	-2.802	FMNL2	formin-like 2	2	152899996	AI123567	114793	2q23.3	Hs.654630	9	actin binding cytoplasm cellular component organization Rho GTPase binding actin cytoskeleton organization
204822_at	0.194	2.579	2.898	1.093e-02	0.172	-2.803	TTK	TTK protein kinase	6	80771077	NM_003318	7272	6q13-q21	Hs.169840	33	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding spindle protein amino acid phosphorylation mitotic spindle organization mitotic cell cycle spindle assembly checkpoint positive regulation of cell proliferation positive regulation of pathway-restricted SMAD protein phosphorylation transferase activity	Cell cycle
231271_x_at	0.362	4.905	2.896	1.095e-02	0.172	-2.805	NMRAL1	NmrA-like family domain containing 1	16	-4451695	AI080701	57407	16p13.3	Hs.288969	8	binding regulation of nitrogen utilization oxidoreductase activity transcription repressor activity oxidation reduction
213579_s_at	-0.473	6.819	-2.896	1.096e-02	0.173	-2.806	EP300	E1A binding protein p300	22	39818559	AI459462	2033	22q13.2	Hs.517517	338	histone acetyltransferase complex response to hypoxia somitogenesis transcription factor activity transcription coactivator activity histone acetyltransferase activity nucleus transcription factor complex nucleolus cytoplasm regulation of transcription, DNA-dependent apoptosis cell cycle signal transduction nervous system development heart development skeletal muscle tissue development protein C-terminus binding zinc ion binding organ morphogenesis acetyltransferase activity histone acetylation transferase activity N-terminal peptidyl-lysine acetylation lung development homeostatic process peroxisome proliferator activated receptor binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter metal ion binding positive regulation of transcription factor activity	Cell cycle Wnt signaling pathway Notch signaling pathway TGF-beta signaling pathway Adherens junction Jak-STAT signaling pathway Long-term potentiation Melanogenesis Huntington's disease Pathways in cancer Renal cell carcinoma Prostate cancer
238057_at	-0.334	5.319	-2.896	1.097e-02	0.173	-2.807	USP45	ubiquitin specific peptidase 45	6	-99986905	AW195800	85015	6q16.2	Hs.143410	6	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding
228274_at	0.617	4.594	2.895	1.098e-02	0.173	-2.808	SDSL	serine dehydratase-like	12	112344598	BE963955	113675	12q24.13	Hs.337594	4	cellular amino acid metabolic process metabolic process lyase activity pyridoxal phosphate binding
235457_at	0.524	5.597	2.895	1.099e-02	0.173	-2.808	MAML2	mastermind-like 2 (Drosophila)	11	-95351087	AI769569	84441	11q21	Hs.428214	17	transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Notch signaling pathway
202519_at	-0.402	9.261	-2.895	1.099e-02	0.173	-2.808	MLXIP	MLX interacting protein	12	121001142	NM_014938	22877	12q24.31	Hs.437153	7	DNA binding nucleus cytoplasm mitochondrion mitochondrial outer membrane membrane transcription regulator activity regulation of transcription
205155_s_at	0.300	5.574	2.894	1.100e-02	0.173	-2.809	SPTBN2	spectrin, beta, non-erythrocytic 2	11	-66209296	NM_006946	6712	11q13	Hs.26915	18	actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton cell cortex spectrin cell death vesicle-mediated transport actin filament capping
204473_s_at	-0.468	6.889	-2.894	1.101e-02	0.173	-2.810	ZNF592	zinc finger protein 592	15	83092821	NM_014630	9640	15q25.3	Hs.79347	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
224015_s_at	0.276	5.549	2.893	1.102e-02	0.173	-2.811	MRPS25	mitochondrial ribosomal protein S25	3	-15065022	BC003590	64432	3p25	Hs.715617	9	structural constituent of ribosome protein binding mitochondrion mitochondrial small ribosomal subunit ribosome translation
226580_at	-0.360	7.477	-2.893	1.102e-02	0.173	-2.811	BRMS1L	breast cancer metastasis-suppressor 1-like	14	35365347	AA779684	84312	14q13.2	Hs.525299	3	nucleus regulation of growth regulation of transcription
235698_at	0.384	5.197	2.893	1.103e-02	0.173	-2.812	ZFP90	zinc finger protein 90 homolog (mouse)	16	67131161	AA771779	146198	16q22.1	Hs.461074 Hs.709017	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203442_x_at	0.310	5.518	2.893	1.103e-02	0.173	-2.812	EML3	echinoderm microtubule associated protein like 3	11	-62126266	AA478965	256364	11q12.3	Hs.379785	8	protein binding cytoplasm microtubule
203406_at	-0.395	7.774	-2.893	1.104e-02	0.173	-2.813	MFAP1	microfibrillar-associated protein 1	15	-41884024	NM_005926	4236	15q15-q21	Hs.61418	9	microfibril molecular_function extracellular region proteinaceous extracellular matrix biological_process
233533_at	-0.249	4.415	-2.893	1.104e-02	0.173	-2.813	KRTAP1-5	keratin associated protein 1-5	17	-36435804, 326122	AJ406928	83895	17q12-q21	Hs.534499	4	molecular_function cellular_component biological_process keratin filament
233974_s_at	0.441	6.381	2.892	1.104e-02	0.173	-2.813	FAM129B	family with sequence similarity 129, member B	9	-129307438, -129307438	AK023580	64855	9q33.3-q34.11	Hs.522401	8
223121_s_at	0.222	5.079	2.892	1.105e-02	0.173	-2.814	SFRP2	secreted frizzled-related protein 2	4	-154921191	AW003584	6423	4q31.3	Hs.481022	37	somitogenesis protein binding extracellular region multicellular organismal development Wnt receptor signaling pathway cell differentiation cellular response to extracellular stimulus	Wnt signaling pathway
224991_at	0.331	4.888	2.891	1.106e-02	0.173	-2.815	CMIP	c-Maf-inducing protein	16	80036275, 80086454	AI819630	80790	16q23	Hs.709248	7	nucleus cytoplasm
202131_s_at	-0.488	7.927	-2.890	1.109e-02	0.173	-2.817	RIOK3	RIO kinase 3 (yeast)	18	19286784	NM_003831	8780	18q11.2	Hs.445511 Hs.719109	9	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation chromosome segregation kinase activity transferase activity
203478_at	0.181	11.672	2.890	1.109e-02	0.173	-2.817	NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	4	-140430540	NM_002494	4717	4q28.2-q31.1	Hs.84549	8	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
227282_at	0.335	4.869	2.890	1.109e-02	0.173	-2.817	PCDH19	protocadherin 19	X	-99433297	AB037734	57526	Xq13.3	Hs.4993	12	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
232704_s_at	-0.384	6.347	-2.890	1.110e-02	0.173	-2.818	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	3	-37069120	AK025207	9209	3p22.2	Hs.719246	7	protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding
236004_at	-0.614	6.871	-2.890	1.110e-02	0.173	-2.818	MUDENG	MU-2/AP1M2 domain containing, death-inducing	14	56805358	AW195610	55745	14q22.3	Hs.597349	9	protein binding intracellular protein transport vesicle-mediated transport clathrin adaptor complex
229435_at	0.397	3.363	2.890	1.110e-02	0.173	-2.818	GLIS3	GLIS family zinc finger 3	9	-3814127, -3814127	AW025602	169792	9p24.2	Hs.162125 Hs.644570	8	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular zinc ion binding nuclear part regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
228316_at	0.385	4.186	2.889	1.111e-02	0.173	-2.818	C2orf63	chromosome 2 open reading frame 63	2	-55253187, -55253187	AA905470	130162	2p16.1	Hs.347014	4	binding
236361_at	0.456	5.836	2.889	1.111e-02	0.173	-2.819	GALNTL2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2	3	16191187	BF432376	117248	3p25.1	Hs.411308	10	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups transport vesicle manganese ion binding	O-Glycan biosynthesis Metabolic pathways
208288_at	0.262	2.346	2.888	1.113e-02	0.174	-2.820	ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	2	-169487694	NM_003742	8647	2q24	Hs.658439	40	nucleotide binding transporter activity ATP binding membrane fraction integral to plasma membrane transport sodium-exporting ATPase activity, phosphorylative mechanism bile acid-exporting ATPase activity membrane ATPase activity apical part of cell intercellular canaliculus	ABC transporters
225293_at	0.509	7.295	2.888	1.113e-02	0.174	-2.821	COL27A1	collagen, type XXVII, alpha 1	9	115958051	AK021957	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
221530_s_at	-0.707	9.452	-2.888	1.115e-02	0.174	-2.822	BHLHE41	basic helix-loop-helix family, member e41	12	-26164227	BE857425	79365	12p11.23-p12.1	Hs.177841	15	transcription factor activity nucleus regulation of transcription, DNA-dependent cell proliferation organ morphogenesis cell differentiation	Circadian rhythm - mammal
219000_s_at	0.397	5.478	2.888	1.115e-02	0.174	-2.822	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)	8	-120915362	NM_024094	79075	8q24.12	Hs.315167	8	chromosome, centromeric region chromatin DNA binding protein binding nucleus nucleoplasm DNA replication cell cycle maintenance of mitotic sister chromatid cohesion
201560_at	0.677	7.923	2.887	1.115e-02	0.174	-2.822	CLIC4	chloride intracellular channel 4	1	24944346	NM_013943	25932	1p36.11	Hs.440544 Hs.595507	25	voltage-gated ion channel activity voltage-gated chloride channel activity protein binding intracellular soluble fraction nucleus cytoplasm mitochondrion plasma membrane microvillus ion transport chloride transport actin cytoskeleton integral to membrane cell differentiation negative regulation of cell migration chloride ion binding cytoplasmic vesicle chloride channel complex
218806_s_at	0.266	3.654	2.887	1.115e-02	0.174	-2.822	VAV3	vav 3 guanine nucleotide exchange factor	1	-107915304, -107915304	AF118887	10451	1p13.3	Hs.267659	21	SH3/SH2 adaptor activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular small GTPase mediated signal transduction zinc ion binding diacylglycerol binding regulation of Rho protein signal transduction metal ion binding	Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton
244761_at	0.298	4.278	2.887	1.117e-02	0.174	-2.823	FLJ44606	glutaredoxin-like protein YDR286C homolog	5		BE674694	401207	5q23.2	Hs.49573	1	transport electron transport chain
225021_at	-0.419	7.421	-2.887	1.117e-02	0.174	-2.824	ZNF532	zinc finger protein 532	18	54681040	AA861416	55205	18q21.32	Hs.529023 Hs.607676	4	DNA binding intracellular nucleus nucleolus Golgi apparatus zinc ion binding regulation of transcription metal ion binding
200884_at	1.121	8.378	2.885	1.120e-02	0.174	-2.826	CKB	creatine kinase, brain	14	-103055748	NM_001823	1152	14q32	Hs.173724	40	nucleotide binding creatine kinase activity protein binding ATP binding cytoplasm mitochondrion cytosol creatine metabolic process brain development cellular chloride ion homeostasis	Arginine and proline metabolism Metabolic pathways
218387_s_at	0.340	6.166	2.885	1.121e-02	0.174	-2.827	PGLS	6-phosphogluconolactonase	19	17483431	NM_012088	25796	19p13.2	Hs.466165	5	carbohydrate metabolic process pentose-phosphate shunt hydrolase activity 6-phosphogluconolactonase activity	Pentose phosphate pathway Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
221363_x_at	0.242	2.910	2.885	1.121e-02	0.174	-2.827	GPR25	G protein-coupled receptor 25	1	199108788	NM_005298	2848	1q32.1	Hs.534316	4	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway
226019_at	-0.477	7.391	-2.885	1.121e-02	0.174	-2.827	OMA1	OMA1 homolog, zinc metallopeptidase (S. cerevisiae)	1	-58718978	AI927931	115209	1p32.2-p32.1	Hs.425769	4	metalloendopeptidase activity mitochondrion proteolysis peptidase activity zinc ion binding membrane integral to membrane metal ion binding
205120_s_at	-0.387	8.075	-2.884	1.122e-02	0.174	-2.828	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	4	-52581617	U29586	6443	4q12	Hs.438953	28	cytoplasm cytoskeleton plasma membrane integral to plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
238798_at	-0.454	4.930	-2.884	1.122e-02	0.174	-2.828	TAPT1	transmembrane anterior posterior transformation 1	4	-15771225	AA811306	202018	4p15.32	Hs.479223	5	receptor activity multicellular organismal development membrane integral to membrane
201371_s_at	-0.400	9.427	-2.884	1.123e-02	0.174	-2.828	CUL3	cullin 3	2	-225043112	AF062537	8452	2q36.2	Hs.372286	39	G1/S transition of mitotic cell cycle protein binding nucleus Golgi apparatus ubiquitin-dependent protein catabolic process cell cycle arrest cyclin catabolic process positive regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
65635_at	0.266	7.621	2.884	1.124e-02	0.174	-2.829	ENGASE	endo-beta-N-acetylglucosaminidase	17	74582613	AL044097	64772	17q25.3	Hs.29288	5	intracellular cytoplasm cytosol metabolic process hydrolase activity, acting on glycosyl bonds mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	Other glycan degradation
201854_s_at	-0.448	7.057	-2.884	1.124e-02	0.174	-2.829	ATMIN	ATM interactor	16	79626958	AI744148	23300	16q23.2	Hs.16349 Hs.589959	9	intracellular nucleus response to DNA damage stimulus zinc ion binding metal ion binding
205345_at	-0.617	5.725	-2.884	1.124e-02	0.174	-2.829	BARD1	BRCA1 associated RING domain 1	2	-215301519	NM_000465	580	2q34-q35	Hs.591642	100	ubiquitin ligase complex tissue homeostasis RNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleus cytoplasm DNA repair response to DNA damage stimulus cell cycle arrest zinc ion binding protein ubiquitination ligase activity kinase binding modification-dependent protein catabolic process BRCA1-BARD1 complex negative regulation of mRNA 3'-end processing regulation of phosphorylation protein homodimerization activity positive regulation of apoptosis negative regulation of apoptosis positive regulation of protein catabolic process negative regulation of protein export from nucleus metal ion binding protein heterodimerization activity BRCA1-A complex
206405_x_at	-0.908	8.049	-2.883	1.125e-02	0.174	-2.830	USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	17	4972410	NM_004505	9098	17p13	Hs.448851	21	nucleic acid binding cysteine-type endopeptidase activity ubiquitin thiolesterase activity Rab GTPase activator activity protein binding intracellular lysosome protein modification process ubiquitin-dependent protein catabolic process peptidase activity regulation of Rab GTPase activity
38671_at	0.291	7.151	2.883	1.126e-02	0.174	-2.831	PLXND1	plexin D1	3	-130756745	AB014520	23129	3q22.1	Hs.301685	10	receptor activity intracellular plasma membrane signal transduction multicellular organismal development integral to membrane
202850_at	-0.420	9.111	-2.883	1.126e-02	0.174	-2.831	ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	1	94656520, 94656520	NM_002858	5825	1p22-p21	Hs.700576	25	nucleotide binding protein binding ATP binding peroxisome peroxisomal membrane integral to peroxisomal membrane transport peroxisome organization peroxisomal long-chain fatty acid import membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters
224956_at	-0.515	6.367	-2.883	1.126e-02	0.174	-2.831	NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	17	-24606979	AI743689	57532	17q11.2	Hs.462598	13	RNA binding protein binding nucleus cytoplasm Golgi apparatus polysomal ribosome
226129_at	0.311	4.278	2.882	1.127e-02	0.174	-2.831	FAM83H	family with sequence similarity 83, member H	8	-144878090	AI949095	286077	8q24.3	Hs.67776 Hs.713170	7	biomineral formation
230813_at	0.249	6.161	2.882	1.127e-02	0.174	-2.832	LEPREL1	leprecan-like 1	3	-191157211, -191157211	BF434223	55214	3q28	Hs.374191	11	iron ion binding endoplasmic reticulum Golgi apparatus oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen procollagen-proline 3-dioxygenase activity L-ascorbic acid binding metal ion binding oxidation reduction
AFFX-HUMGAPDH/M33197_5_at	-0.219	13.603	-2.882	1.127e-02	0.174	-2.832	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	AFFX-HUMGAPDH/M33197_5	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
212657_s_at	0.292	4.343	2.882	1.127e-02	0.174	-2.832	IL1RN	interleukin 1 receptor antagonist	2	113591940, 113601608	U65590	3557	2q14.2	Hs.81134	610	cytokine activity interleukin-1 receptor antagonist activity protein binding extracellular region extracellular space intracellular cytoplasm inflammatory response immune response response to glucocorticoid stimulus
204660_at	0.241	4.927	2.882	1.128e-02	0.174	-2.833	GFER	growth factor, augmenter of liver regeneration	16	1974150	NM_005262	2671	16p13.3-p13.12	Hs.27184	30	protein binding cellular_component mitochondrion spermatogenesis cell proliferation oxidoreductase activity thiol oxidase activity oxidation reduction
228463_at	0.262	3.830	2.882	1.129e-02	0.174	-2.833	FOXA3	forkhead box A3	19	51059357	R99562	3171	19q13.2-q13.4	Hs.36137	14	cellular glucose homeostasis transcription factor activity nucleus regulation of transcription, DNA-dependent cellular response to starvation sequence-specific DNA binding	Maturity onset diabetes of the young
222553_x_at	-0.355	9.006	-2.881	1.129e-02	0.174	-2.833	OXR1	oxidation resistance 1	8	107351648, 107739211	AL541048	55074	8q23	Hs.148778	11	molecular_function cellular_component nucleolus mitochondrion response to oxidative stress cell wall macromolecule catabolic process
207521_s_at	-0.246	4.248	-2.881	1.129e-02	0.174	-2.833	ATP2A3	ATPase, Ca++ transporting, ubiquitous	17	-3773917	AF068220	489	17p13.3	Hs.513870	27	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding protein binding ATP binding nucleus ATP biosynthetic process cation transport calcium ion transport metabolic process membrane integral to membrane sarcoplasmic reticulum hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway Alzheimer's disease
209303_at	0.351	10.252	2.881	1.130e-02	0.175	-2.834	NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	5	52892221	BC005270	4724	5q11.1	Hs.528222	28	regulation of protein amino acid phosphorylation mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport brain development NADH dehydrogenase (ubiquinone) activity membrane oxidoreductase activity, acting on NADH or NADPH cAMP-mediated signaling electron transport chain mitochondrial respiratory chain complex I assembly cellular respiration positive regulation of fibroblast proliferation response to cAMP respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
209759_s_at	0.374	9.160	2.881	1.131e-02	0.175	-2.835	DCI	dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)	16	-2229898	BC002746	1632	16p13.3	Hs.403436	6	dodecenoyl-CoA delta-isomerase activity mitochondrion mitochondrial inner membrane mitochondrial matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process isomerase activity	Fatty acid metabolism
232207_at	-0.362	5.575	-2.880	1.133e-02	0.175	-2.836	GUSBL2	glucuronidase, beta-like 2	6	-58354117	AK026691	375513	6p11.2	Hs.561539 Hs.711053	5
214687_x_at	-0.339	13.496	-2.880	1.133e-02	0.175	-2.837	ALDOA	aldolase A, fructose-bisphosphate	16	29971991, 29983100, 29983473, 29984544	AK026577	226	16p11.2	Hs.513490	55	actin binding fructose-bisphosphate aldolase activity glycolysis ATP biosynthetic process striated muscle contraction actin filament organization metabolic process regulation of cell shape actin cytoskeleton tubulin binding lyase activity fructose 1,6-bisphosphate metabolic process I band identical protein binding muscle maintenance fructose binding extracellular vesicular exosome	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
200760_s_at	-0.443	10.202	-2.879	1.134e-02	0.175	-2.837	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	3	69216779	N92494	10550	3p14	Hs.518060 Hs.716493	30	protein binding cytoplasm endoplasmic reticulum L-glutamate transport membrane integral to membrane
210862_s_at	0.259	3.986	2.879	1.134e-02	0.175	-2.838	SARDH	sarcosine dehydrogenase	9	-135518506, -135518506	AF047190	1757	9q33-q34	Hs.198003	11	aminomethyltransferase activity cytoplasm mitochondrion mitochondrial matrix glycine catabolic process sarcosine dehydrogenase activity oxidoreductase activity oxidation reduction	Glycine, serine and threonine metabolism Metabolic pathways
224016_at	0.373	4.903	2.879	1.135e-02	0.175	-2.838	HIPK2	homeodomain interacting protein kinase 2	7	-138896855	AF111850	28996	7q32-q34	Hs.397465 Hs.632033	66	nucleotide binding transcription corepressor activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation apoptosis DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator induction of apoptosis by intracellular signals PML body transferase activity virus-host interaction positive regulation of transforming growth factor beta receptor signaling pathway nuclear membrane regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of JNK cascade virion binding
223343_at	0.779	4.146	2.879	1.136e-02	0.175	-2.839	MS4A7	membrane-spanning 4-domains, subfamily A, member 7	11	59902533	AI301935	58475	11q12	Hs.530735	10	receptor activity signal transduction membrane integral to membrane
217874_at	0.282	10.903	2.878	1.136e-02	0.175	-2.839	SUCLG1	succinate-CoA ligase, alpha subunit	2	-84504162	NM_003849	8802	2p11.2	Hs.270428	10	nucleotide binding ATP citrate synthase activity succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity GTP binding mitochondrion mitochondrial inner membrane mitochondrial matrix tricarboxylic acid cycle metabolic process ligase activity	Citrate cycle (TCA cycle) Propanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
205799_s_at	0.366	2.425	2.878	1.138e-02	0.175	-2.840	SLC3A1	solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1	2	44356100	M95548	6519	2p16.3	Hs.112916	44	catalytic activity membrane fraction integral to plasma membrane carbohydrate metabolic process cellular amino acid metabolic process transport basic amino acid transmembrane transporter activity L-cystine transmembrane transporter activity basic amino acid transport L-cystine transport membrane cation binding
205945_at	-1.029	5.699	-2.878	1.138e-02	0.175	-2.841	IL6R	interleukin 6 receptor	1	152644292	NM_000565	3570	1q21	Hs.709210	132	hepatic immune response monocyte chemotaxis positive regulation of leukocyte chemotaxis receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity receptor binding extracellular region plasma membrane interleukin-6 receptor complex acute-phase response integral to membrane apical plasma membrane enzyme binding endocrine pancreas development endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production response to cytokine stimulus positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity regulation of apoptosis positive regulation of osteoblast differentiation positive regulation of anti-apoptosis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium interleukin-6-mediated signaling pathway ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
212350_at	-0.680	7.557	-2.877	1.138e-02	0.175	-2.841	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	4	37569114	AB029031	23216	4p14	Hs.176503	15	GTPase activator activity Rab GTPase activator activity intracellular nucleus regulation of Rab GTPase activity
226280_at	-0.295	8.481	-2.877	1.138e-02	0.175	-2.841	BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	15	-57742353	AA133277	663	15q22.2	Hs.646490	15	GTPase activator activity calcium ion binding protein binding nuclear envelope cytoplasm apoptosis anti-apoptosis intracellular membrane-bounded organelle perinuclear region of cytoplasm
235499_at	0.385	5.932	2.877	1.139e-02	0.175	-2.842	tcag7.1196	similar to GLI-Kruppel family member HKR1	7	149733772	AI660326	728743	7q36.1	Hs.655734	2
225497_at	-0.404	7.747	-2.876	1.140e-02	0.175	-2.842	ATE1	arginyltransferase 1	10	-123492614	AL589591	11101	10q26.13	Hs.632080	6	arginyltransferase activity nucleus cytoplasm acyltransferase activity protein arginylation transferase activity modification-dependent protein catabolic process
233520_s_at	-0.344	12.478	-2.876	1.141e-02	0.175	-2.843	CMYA5	cardiomyopathy associated 5	5	79021414	AL359338	202333	5q14.1	Hs.482625	7	cytoplasm identical protein binding perinuclear region of cytoplasm
209526_s_at	0.433	5.543	2.876	1.141e-02	0.175	-2.843	HDGFRP3	hepatoma-derived growth factor, related protein 3	15	-81597819	AB029156	50810	15q25.2	Hs.513954	9	nucleus cytoplasm growth factor activity cell proliferation
213645_at	-0.808	6.686	-2.876	1.141e-02	0.175	-2.843	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	AF305057	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
218786_at	-0.357	6.181	-2.876	1.142e-02	0.175	-2.844	NT5DC3	5'-nucleotidase domain containing 3	12	-102690210	NM_016575	51559	12q22-q23.1	Hs.48428	4	magnesium ion binding hydrolase activity
228588_s_at	-0.511	9.960	-2.876	1.142e-02	0.175	-2.844	UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	5	133734768	AI499236	7320	5q23-q31	Hs.615284 Hs.644421	23	nucleotide binding protein polyubiquitination chromatin ubiquitin-protein ligase activity ubiquitin-protein ligase activity protein binding ATP binding nucleus replication fork cytoplasm plasma membrane postreplication repair postreplication repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process protein monoubiquitination response to DNA damage stimulus spermatogenesis sperm axoneme assembly response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination response to drug protein stabilization regulation of protein metabolic process protein autoubiquitination Wnt receptor signaling pathway through beta-catenin	Ubiquitin mediated proteolysis
224374_s_at	0.358	4.648	2.876	1.143e-02	0.175	-2.844	EMILIN2	elastin microfibril interfacer 2	18	2837027	AF270513	84034	18p11.3	Hs.532815	5	protein binding extracellular region proteinaceous extracellular matrix cell adhesion biological_process extracellular matrix constituent conferring elasticity
222465_at	-0.336	9.339	-2.875	1.144e-02	0.176	-2.845	RSL24D1	ribosomal L24 domain containing 1	15	-53260803	AF165521	51187	15q21	Hs.274772 Hs.593056	10	structural constituent of ribosome intracellular nucleus nucleolus ribosome translation ribosome biogenesis	Ribosome
202213_s_at	-0.470	5.706	-2.874	1.146e-02	0.176	-2.847	CUL4B	cullin 4B	X	-119542473, -119542473	AI650819	8450	Xq23	Hs.102914	28	molecular_function protein binding cellular_component DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
218679_s_at	0.382	8.927	2.874	1.147e-02	0.176	-2.847	VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	8	-145619807	NM_016208	51160	8q24.3	Hs.418175	18	protein binding cytoplasm endosome cytosol plasma membrane protein transport negative regulation of protein ubiquitination	Endocytosis
217115_at	0.239	5.152	2.873	1.148e-02	0.176	-2.848	LOC100240726	makorin ring finger protein 1 pseudogene	20	-44525707	AL031686	100240726	20q13.12		1
212434_at	0.271	8.602	2.873	1.148e-02	0.176	-2.849	GRPEL1	GrpE-like 1, mitochondrial (E. coli)	4	-7112680	AI984421	80273	4p16	Hs.443723	6	adenyl-nucleotide exchange factor activity mitochondrion mitochondrial matrix protein folding protein import into mitochondrial matrix protein homodimerization activity unfolded protein binding chaperone binding
226635_at	-0.500	7.121	-2.873	1.149e-02	0.176	-2.850	LOC401504	hypothetical gene supported by AK091718	9		BG170478	401504	9p13.2	Hs.446271	2
200980_s_at	0.289	11.084	2.872	1.150e-02	0.176	-2.850	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	X	19271931	NM_000284	5160	Xp22.2-p22.1	Hs.530331	54	pyruvate dehydrogenase (acetyl-transferring) activity protein binding mitochondrion mitochondrial matrix glycolysis oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
229986_at	0.214	5.812	2.872	1.151e-02	0.176	-2.851	ZNF717	zinc finger protein 717	3	-75868718	AW205616	100131827	3p12.3	Hs.556877	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
213597_s_at	0.205	2.947	2.872	1.152e-02	0.176	-2.851	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	3	37878672	BF002474	10217	3p21.3	Hs.475963	18	molecular_function phosphoprotein phosphatase activity cellular_component nucleus biological_process hydrolase activity
209440_at	-0.324	8.355	-2.871	1.153e-02	0.176	-2.852	PRPS1	phosphoribosyl pyrophosphate synthetase 1	X	106758309	BC001605	5631	Xq21.32-q24	Hs.56	26	nucleotide binding magnesium ion binding ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding cytosol purine base metabolic process purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process kinase activity transferase activity urate biosynthetic process protein homodimerization activity hypoxanthine biosynthetic process	Pentose phosphate pathway Purine metabolism Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
225346_at	0.440	6.759	2.871	1.153e-02	0.176	-2.853	MTERFD3	MTERF domain containing 3	12	-105895198	NM_025198	80298	12q24.1	Hs.5009	6	mitochondrion transcription termination regulation of transcription
1569909_at	0.315	4.352	2.871	1.153e-02	0.176	-2.853	KRT79	keratin 79	12	-51501497	BC039148	338785	12q13.13	Hs.711471	3	structural molecule activity keratin filament
211716_x_at	0.256	6.781	2.870	1.154e-02	0.176	-2.854	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	17	-77418885	BC005851	396	17q25.3	Hs.159161	38	Rho GDP-dissociation inhibitor activity GTPase activator activity cytoplasm cytoskeleton anti-apoptosis cell motion negative regulation of cell adhesion Rho protein signal transduction identical protein binding	Neurotrophin signaling pathway
227685_at	-0.588	6.210	-2.870	1.155e-02	0.176	-2.854	TMF1	TATA element modulatory factor 1	3	-69151667	AI767750	7110	3p21-p12	Hs.267632	15	Golgi membrane DNA binding RNA polymerase II transcription factor activity transcription cofactor activity protein binding nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter membrane
227859_at	-0.381	6.463	-2.870	1.156e-02	0.177	-2.855	DNAJC27	DnaJ (Hsp40) homolog, subfamily C, member 27	2	-25020008	AV706343	51277	2p23.3	Hs.434993	4	nucleotide binding GTP binding small GTPase mediated signal transduction heat shock protein binding
201722_s_at	-0.520	8.042	-2.870	1.156e-02	0.177	-2.855	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	AV692127	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
227307_at	0.396	6.044	2.870	1.156e-02	0.177	-2.855	TSPAN18	tetraspanin 18	11	44838454, 44884532	AL565381	90139	11p11.2	Hs.385634 Hs.638940	6	membrane integral to membrane
1570183_at	-0.218	2.139	-2.869	1.158e-02	0.177	-2.857	FBXO34	F-box protein 34	14	54807773, 54808624	BC020583	55030	14q22.3	Hs.525348 Hs.654725	9	protein transport modification-dependent protein catabolic process
203352_at	-0.451	5.587	-2.869	1.158e-02	0.177	-2.857	ORC4L	origin recognition complex, subunit 4-like (yeast)	2	-148408201, -148408201	NM_002552	5000	2q22-q23	Hs.558364	29	nucleotide binding DNA binding DNA replication origin binding protein binding ATP binding nucleus nucleoplasm DNA replication DNA replication DNA replication initiation nucleoside-triphosphatase activity	Cell cycle
1554026_a_at	0.271	4.354	2.869	1.159e-02	0.177	-2.857	MYO10	myosin X	5	-16715015	BC041694	4651	5p15.1-p14.3	Hs.481720	19	nucleotide binding motor activity actin binding ATP binding cytoskeleton signal transduction myosin complex	Fc gamma R-mediated phagocytosis
225643_at	-0.364	7.374	-2.868	1.159e-02	0.177	-2.857	MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	14	54588114	AI261542	93487	14q22.3	Hs.594338 Hs.619374	8
234405_s_at	-0.490	6.798	-2.868	1.160e-02	0.177	-2.858	PHAX	phosphorylated adaptor for RNA export	5	125964531	AK024065	51808	5q23.2	Hs.555731 Hs.719165	10	spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol snRNA export from nucleus Cajal body protein transport
201315_x_at	0.459	8.833	2.868	1.161e-02	0.177	-2.859	IFITM2	interferon induced transmembrane protein 2 (1-8D)	11	298106	NM_006435	10581	11p15.5	Hs.709321	6	protein binding immune response response to biotic stimulus membrane integral to membrane
212696_s_at	-0.260	7.542	-2.867	1.162e-02	0.177	-2.859	RNF4	ring finger protein 4	4	2440604	BF968633	6047	4p16.3	Hs.66394	19	transcription factor activity transcription coactivator activity protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter zinc ion binding androgen receptor signaling pathway regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding
221666_s_at	0.369	5.140	2.867	1.162e-02	0.177	-2.860	PYCARD	PYD and CARD domain containing	16	-31120307	BC004470	29108	16p12-p11.2	Hs.499094	56	cysteine-type endopeptidase activity protein binding intracellular cytoplasm proteolysis induction of apoptosis activation of caspase activity signal transduction IkappaB kinase complex caspase activator activity Pyrin domain binding tumor necrosis factor-mediated signaling pathway protein homodimerization activity regulation of apoptosis positive regulation of interleukin-1 beta secretion positive regulation of NF-kappaB transcription factor activity
232003_at	0.197	5.310	2.867	1.162e-02	0.177	-2.860	PNMAL2	PNMA-like 2	19	-51686287	AW299761	57469	19q13.32	Hs.7193	3
243_g_at	-0.470	9.788	-2.866	1.165e-02	0.177	-2.862	MAP4	microtubule-associated protein 4	3	-47989573, -47867183, -47867183	M64571	4134	3p21	Hs.517949	40	structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization
200037_s_at	-0.317	9.593	-2.866	1.166e-02	0.177	-2.862	CBX3	chromobox homolog 3 (HP1 gamma homolog, Drosophila)	7	26207623, 26207848	NM_016587	11335	7p15.2	Hs.381189 Hs.706294	45	condensed chromosome, centromeric region chromatin chromatin binding nucleus nuclear inner membrane polytene chromosome chromocenter nuclear euchromatin spindle chromatin assembly or disassembly chromatin remodeling negative regulation of transcription general transcriptional repressor activity enzyme binding protein domain specific binding nuclear centromeric heterochromatin
221873_at	-0.383	6.635	-2.866	1.166e-02	0.177	-2.863	ZNF143	zinc finger protein 143	11	9439088	AW162015	7702	11p15.4	Hs.523471	14	DNA binding specific RNA polymerase II transcription factor activity RNA polymerase III transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase III promoter zinc ion binding regulation of transcription metal ion binding
211908_x_at	0.286	5.897	2.865	1.167e-02	0.177	-2.863	IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)	14		M87268	3500	14q32.33	Hs.510635	29	antigen binding protein binding extracellular region membrane fraction immune response
219689_at	0.666	6.378	2.865	1.167e-02	0.177	-2.864	SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	3	-52442307	NM_020163	56920	3p21.1	Hs.59729	6	receptor activity extracellular region multicellular organismal development membrane	Axon guidance
236930_at	-0.335	3.244	-2.864	1.169e-02	0.177	-2.865	NUMB	numb homolog (Drosophila)	14	-72811670	AW167424	8650	14q24.3	Hs.654609 Hs.714879	40	protein binding integral to plasma membrane multicellular organismal development membrane	Notch signaling pathway
213974_at	0.407	5.344	2.864	1.169e-02	0.177	-2.865	ADAMTSL3	ADAMTS-like 3	15	82113841	AB033059	57188	15q25.2	Hs.459162	11	extracellular region proteinaceous extracellular matrix peptidase activity metallopeptidase activity zinc ion binding
227961_at	-0.373	7.808	-2.864	1.169e-02	0.177	-2.865	CTSB	cathepsin B	8	-11737442	AA130998	1508	8p22	Hs.520898	140	cysteine-type endopeptidase activity extracellular region intracellular soluble fraction mitochondrion lysosome proteolysis peptidase activity response to wounding external side of plasma membrane apical plasma membrane kininogen binding peptide binding melanosome regulation of apoptosis regulation of catalytic activity	Lysosome Antigen processing and presentation
226157_at	-0.434	7.296	-2.864	1.171e-02	0.177	-2.866	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	AI569747	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
226851_at	0.458	7.981	2.864	1.171e-02	0.177	-2.866	LYPLAL1	lysophospholipase-like 1	1	217413814	AW612657	127018	1q41	Hs.657617	6	lysophospholipase activity cellular_component cytoplasm biological_process hydrolase activity
1552364_s_at	-0.353	5.143	-2.863	1.171e-02	0.177	-2.867	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BC001526	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
203810_at	-0.600	8.517	-2.863	1.173e-02	0.178	-2.868	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1	78243223	BG252490	11080	1p31.1	Hs.13852	11	protein folding response to unfolded protein response to heat heat shock protein binding unfolded protein binding
209704_at	-0.440	4.355	-2.863	1.173e-02	0.178	-2.868	MTF2	metal response element binding transcription factor 2	1	93317379	AL523380	22823	1p22.1	Hs.31016	5	DNA binding protein binding nucleus zinc ion binding metal ion binding
204304_s_at	0.758	4.200	2.863	1.173e-02	0.178	-2.868	PROM1	prominin 1	4	-15578946, -15578946, -15578946	NM_006017	8842	4p15.32	Hs.614734	81	extracellular space plasma membrane integral to plasma membrane brush border visual perception cell surface apical plasma membrane stereocilium response to stimulus
201816_s_at	-0.367	11.867	-2.863	1.173e-02	0.178	-2.868	GBAS	glioblastoma amplified sequence	7	55999789	NM_001483	2631	7p12	Hs.591069	9	membrane fraction mitochondrion integral to plasma membrane
214835_s_at	-0.390	9.573	-2.862	1.175e-02	0.178	-2.870	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	3	-67507832	AF131748	8801	3p14.1	Hs.655250	8	nucleotide binding succinate-CoA ligase (GDP-forming) activity ATP binding GTP binding mitochondrion mitochondrial matrix tricarboxylic acid cycle succinyl-CoA metabolic process metabolic process ligase activity	Citrate cycle (TCA cycle) Propanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
212328_at	-0.373	9.315	-2.861	1.176e-02	0.178	-2.870	LIMCH1	LIM and calponin homology domains 1	4	41057560, 41309675	AB029025	22998	4p13	Hs.335163	10	actin binding zinc ion binding actomyosin structure organization metal ion binding
206363_at	-0.590	7.545	-2.861	1.176e-02	0.178	-2.870	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	16	-78185246	NM_005360	4094	16q22-q23	Hs.134859	37	chromatin cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of chondrocyte differentiation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cell development lens fiber cell differentiation
201636_at	-0.415	11.014	-2.861	1.176e-02	0.178	-2.871	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	BG025078	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
204723_at	0.812	5.615	2.861	1.176e-02	0.178	-2.871	SCN3B	sodium channel, voltage-gated, type III, beta	11	-123005104	AB032984	55800	11q23.3	Hs.4865	19	voltage-gated ion channel activity voltage-gated sodium channel activity plasma membrane ion transport sodium ion transport integral to membrane sodium ion binding
1558706_a_at	1.002	5.204	2.861	1.178e-02	0.178	-2.872	ATOH8	atonal homolog 8 (Drosophila)	2	85834419	AL831857	84913	2p11.2	Hs.135569 Hs.436464	5	DNA binding nucleus multicellular organismal development nervous system development cell differentiation transcription regulator activity regulation of transcription
240098_at	0.318	5.517	2.861	1.178e-02	0.178	-2.872	RIF1	RAP1 interacting factor homolog (yeast)	2	151974673	AI168689	55183	2q23.3	Hs.655671	10	chromosome, telomeric region female pronucleus male pronucleus binding nucleus chromosome response to DNA damage stimulus cell cycle stem cell maintenance
1562625_at	-0.318	3.701	-2.859	1.181e-02	0.178	-2.874	FRYL	FRY-like	4	-48194136	BC040987	285527	4p11	Hs.631525	8	protein binding regulation of transcription
238911_at	0.284	5.103	2.859	1.181e-02	0.178	-2.875	STARD10	StAR-related lipid transfer (START) domain containing 10	11	-72143421	AW328672	10809	11q13	Hs.188606	8
225566_at	0.380	4.850	2.859	1.182e-02	0.178	-2.875	NRP2	neuropilin 2	2	206255468, 206255468, 206255468	AI819729	8828	2q33.3	Hs.471200	44	receptor activity vascular endothelial growth factor receptor activity membrane fraction plasma membrane cell adhesion multicellular organismal development nervous system development axon guidance integral to membrane cell differentiation
220741_s_at	0.253	9.050	2.858	1.184e-02	0.178	-2.876	PPA2	pyrophosphatase (inorganic) 2	4	-106509682	NM_006903	27068	4q25	Hs.654957	13	magnesium ion binding inorganic diphosphatase activity cytoplasm mitochondrion phosphate metabolic process hydrolase activity	Oxidative phosphorylation
215203_at	-0.677	7.692	-2.858	1.184e-02	0.178	-2.877	GOLGA4	golgi autoantigen, golgin subfamily a, 4	3	37259741	AW438464	2803	3p22-p21.3	Hs.344151	21	cytoplasm Golgi apparatus trans-Golgi network membrane vesicle-mediated transport
202465_at	0.536	6.353	2.858	1.184e-02	0.178	-2.877	PCOLCE	procollagen C-endopeptidase enhancer	7	100037817	NM_002593	5118	7q22	Hs.202097	18	protein binding extracellular region multicellular organismal development
233880_at	0.263	4.869	2.858	1.184e-02	0.178	-2.877	RNF213	ring finger protein 213	17	75928320	AL161961	57674	17q25.3	Hs.195642 Hs.657519	6	nucleotide binding protein binding zinc ion binding nucleoside-triphosphatase activity metal ion binding
210720_s_at	0.354	7.677	2.857	1.186e-02	0.179	-2.878	NECAB3	N-terminal EF-hand calcium binding protein 3	20	-31708553	AB039947	63941	20q11.22	Hs.516986	11	Golgi cis cisterna Golgi cis cisterna calcium ion binding protein binding protein binding protein binding nucleus cytoplasm cytoplasm endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus protein secretion oxidoreductase activity antibiotic biosynthetic process protein metabolic process protein metabolic process regulation of amyloid precursor protein biosynthetic process
211744_s_at	-0.432	5.471	-2.857	1.187e-02	0.179	-2.879	CD58	CD58 molecule	1	-116862845, -116858679	BC005930	965	1p13	Hs.34341	38	protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane	Cell adhesion molecules (CAMs)
205862_at	0.724	4.545	2.857	1.187e-02	0.179	-2.879	GREB1	GREB1 protein	2	11591692, 11597530, 11600301	NM_014668	9687	2p25.1	Hs.467733	11	membrane integral to membrane
218890_x_at	0.710	8.628	2.857	1.188e-02	0.179	-2.879	MRPL35	mitochondrial ribosomal protein L35	2	86280066	NM_016622	51318	2p11.2	Hs.433439	8	structural constituent of ribosome mitochondrion mitochondrial ribosome ribosome translation translation regulator activity
205333_s_at	0.241	5.335	2.856	1.190e-02	0.179	-2.881	RCE1	RCE1 homolog, prenyl protein peptidase (S. cerevisiae)	11	66367458	NM_005133	9986	11q13	Hs.654972	9	metalloendopeptidase activity endoplasmic reticulum integral to plasma membrane proteolysis membrane hydrolase activity
242287_at	-0.546	6.343	-2.856	1.190e-02	0.179	-2.881	CLIP1	CAP-GLY domain containing linker protein 1	12	-121321933	AI090487	6249	12q24.3	Hs.524809	37	kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding
206876_at	-1.105	5.968	-2.855	1.191e-02	0.179	-2.882	SIM1	single-minded homolog 1 (Drosophila)	6	-100943470	AL121948	6492	6q16.3-q21	Hs.520293	17	transcription factor activity signal transducer activity protein binding nucleus Golgi apparatus regulation of transcription, DNA-dependent signal transduction multicellular organismal development nervous system development cell differentiation protein heterodimerization activity
221749_at	-0.327	9.188	-2.855	1.192e-02	0.179	-2.883	YTHDF3	YTH domain family, member 3	8	64243674	AU157915	253943	8q12.3	Hs.491861	9	cytoplasm
225838_at	-0.563	6.667	-2.855	1.193e-02	0.179	-2.883	EPC2	enhancer of polycomb homolog 2 (Drosophila)	2	149119029	AK002010	26122	2q23.1	Hs.23270	7	nucleus DNA repair response to DNA damage stimulus chromatin modification regulation of transcription
209019_s_at	-0.340	10.140	-2.854	1.193e-02	0.179	-2.883	PINK1	PTEN induced putative kinase 1	1	20832534	AF316873	65018	1p36	Hs.389171	105	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding mitochondrion mitochondrial outer membrane protein amino acid phosphorylation response to stress protein kinase cascade membrane integral to membrane transferase activity positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion	Parkinson's disease
235272_at	0.288	4.572	2.854	1.193e-02	0.179	-2.883	SBSN	suprabasin	19	-40706110	AI814274	374897	19q13.13	Hs.433484	5	extracellular region cytoplasm
227438_at	0.340	5.751	2.854	1.194e-02	0.179	-2.884	ALPK1	alpha-kinase 1	4	113437947	AI760166	80216	4q25	Hs.652825	10	protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation kinase activity transferase activity
204369_at	-0.548	5.570	-2.854	1.195e-02	0.179	-2.885	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	3	180349004	NM_006218	5290	3q26.3	Hs.553498 Hs.85701	259	nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex glucose metabolic process protein amino acid phosphorylation anti-apoptosis signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor lamellipodium regulation of multicellular organism growth protein kinase B signaling cascade insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
228521_s_at	0.370	6.411	2.854	1.195e-02	0.179	-2.885	RAB4B	RAB4B, member RAS oncogene family	19	45976010	AW242973	53916	19q13.2	Hs.631539	5	nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
1558486_at	0.430	5.671	2.853	1.196e-02	0.179	-2.886	ZNF493	zinc finger protein 493	19	21371760, 21371760	BC022394	284443	19p12	Hs.656558	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
221408_x_at	0.341	4.787	2.853	1.196e-02	0.179	-2.886	PCDHB12	protocadherin beta 12	5	140568474	NM_018932	56124	5q31	Hs.429820 Hs.719589	8	calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion nervous system development
1563455_at	-0.428	4.903	-2.852	1.198e-02	0.179	-2.888	QSK	serine/threonine-protein kinase QSK	11	-116219327	AL832068	23387	11q23.3	Hs.167451	14	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
212232_at	-0.549	8.111	-2.852	1.199e-02	0.179	-2.888	FNBP4	formin binding protein 4	11	-47694644	AB023231	23360	11p11.2	Hs.6834	11	protein binding
226612_at	-0.638	8.605	-2.852	1.199e-02	0.179	-2.888	FLJ25076	probable ubiquitin-conjugating enzyme E2 FLJ25076	5	6501735	H17038	134111	5p15.31	Hs.126856	3	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
223981_at	-0.417	4.197	-2.851	1.202e-02	0.180	-2.891	NIN	ninein (GSK3B interacting protein)	14	-50263700, -50262296, -50262296, -50256230	AF223937	51199	14q22.1	Hs.310429	23	nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization
238356_at	0.251	2.791	2.850	1.202e-02	0.180	-2.891	DOCK11	dedicator of cytokinesis 11	X	117513899	AW968823	139818	Xq24	Hs.368203	4	guanyl-nucleotide exchange factor activity GTP binding GTPase binding
209106_at	-0.372	7.862	-2.850	1.203e-02	0.180	-2.891	NCOA1	nuclear receptor coactivator 1	2	24660849	BF576458	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
227780_s_at	0.336	6.601	2.850	1.203e-02	0.180	-2.891	ECSCR	endothelial cell-specific chemotaxis regulator	5	-138812143	AI422211	641700	5q31.2	Hs.483538 Hs.570903	5	angiogenesis plasma membrane chemotaxis multicellular organismal development integral to membrane cell differentiation
218857_s_at	0.413	6.547	2.850	1.203e-02	0.180	-2.891	ASRGL1	asparaginase like 1	11	61861349	NM_025080	80150	11q12.3	Hs.535326	9	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity cytoplasm hydrolase activity asparagine catabolic process via L-aspartate	Alanine, aspartate and glutamate metabolism Cyanoamino acid metabolism Nitrogen metabolism Metabolic pathways
223879_s_at	-0.599	7.518	-2.850	1.204e-02	0.180	-2.892	OXR1	oxidation resistance 1	8	107351648, 107739211	AF309387	55074	8q23	Hs.148778	11	molecular_function cellular_component nucleolus mitochondrion response to oxidative stress cell wall macromolecule catabolic process
229573_at	-0.516	6.310	-2.849	1.206e-02	0.180	-2.893	USP9X	ubiquitin specific peptidase 9, X-linked	X	40829831	AI659456	8239	Xp11.4	Hs.77578	24	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm ubiquitin-dependent protein catabolic process transforming growth factor beta receptor signaling pathway female gamete generation peptidase activity protein deubiquitination BMP signaling pathway co-SMAD binding
210305_at	-0.882	11.233	-2.849	1.207e-02	0.180	-2.894	PDE4DIP	phosphodiesterase 4D interacting protein	1	-143663117, -143663117, -143601947, -143601947, -143562783	AB042557	9659	1q12	Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077	10	nucleus cytoplasm Golgi apparatus centrosome
227029_at	-0.612	7.302	-2.849	1.207e-02	0.180	-2.894	FAM177A1	family with sequence similarity 177, member A1	14	34583863, 34585360	AI949662	283635	14q13.2	Hs.446357	3
213225_at	-0.490	9.042	-2.848	1.208e-02	0.180	-2.895	PPM1B	protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform	2	44249503, 44249503, 44249503	AJ271832	5495	2p21	Hs.416769	17	magnesium ion binding protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity manganese ion binding	MAPK signaling pathway
226082_s_at	-0.382	6.250	-2.848	1.208e-02	0.180	-2.895	SFRS15	splicing factor, arginine/serine-rich 15	21	-31965183	AW513629	57466	21q22.1	Hs.17255	12	nucleotide binding RNA binding nucleus nucleolus mRNA processing protein C-terminus binding
218066_at	0.338	6.789	2.848	1.209e-02	0.180	-2.896	SLC12A7	solute carrier family 12 (potassium/chloride transporters), member 7	5	-1103488	NM_006598	10723	5p15	Hs.172613	13	transporter activity integral to plasma membrane ion transport potassium ion transport sodium ion transport chloride transport symporter activity potassium:chloride symporter activity membrane potassium ion binding
216513_at	-0.309	2.907	-2.847	1.210e-02	0.180	-2.897	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	AL139318	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
225913_at	0.284	7.846	2.847	1.211e-02	0.180	-2.897	SGK269	NKF3 kinase family member	15	-75187525	AK025943	79834	15q24.3	Hs.9587	7	nucleotide binding non-membrane spanning protein tyrosine kinase activity ATP binding protein amino acid phosphorylation transferase activity
225726_s_at	0.693	5.398	2.846	1.213e-02	0.180	-2.899	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	14	67069760	AB033026	57475	14q24.1	Hs.594236	4	binding cytoskeleton
213426_s_at	0.255	4.351	2.846	1.214e-02	0.180	-2.899	CAV2	caveolin 2	7	115926679	AA150110	858	7q31.1	Hs.212332 Hs.603096	50	negative regulation of endothelial cell proliferation protein binding intracellular Golgi apparatus plasma membrane integral to plasma membrane caveola vesicle fusion mitochondrion organization endoplasmic reticulum organization transport vesicle protein homodimerization activity vesicle docking perinuclear region of cytoplasm skeletal muscle fiber development protein oligomerization	Focal adhesion
203748_x_at	0.288	7.716	2.846	1.214e-02	0.180	-2.900	RBMS1	RNA binding motif, single stranded interacting protein 1	2	-160836908	NM_016839	5937	2q24.2	Hs.470412	12	DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding cellular_component nucleus DNA replication RNA processing
235981_at	-1.937	10.437	-2.846	1.214e-02	0.180	-2.900	C8orf22	chromosome 8 open reading frame 22	8	50147455	N70563	492307	8q11	Hs.49890	2
214265_at	0.322	5.193	2.845	1.216e-02	0.180	-2.901	ITGA8	integrin, alpha 8	10	-15599093	AI193623	8516	10p13	Hs.171311	15	metanephros development receptor activity calcium ion binding protein binding cell-matrix adhesion integrin-mediated signaling pathway multicellular organismal development nervous system development memory integrin complex membrane integral to membrane cell-cell adhesion cell projection organization cell differentiation extracellular matrix organization positive regulation of transforming growth factor beta receptor signaling pathway inner ear morphogenesis apical part of cell	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
242734_x_at	0.310	4.583	2.845	1.216e-02	0.180	-2.901	GALT	galactose-1-phosphate uridylyltransferase	9	34636634	BF002568	2592	9p13	Hs.522090	72	iron ion binding cytosol carbohydrate metabolic process galactose metabolic process UDP-glucose:hexose-1-phosphate uridylyltransferase activity UDP-glucose:hexose-1-phosphate uridylyltransferase activity zinc ion binding transferase activity nucleotidyltransferase activity metal ion binding	Galactose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
226992_at	0.519	5.455	2.845	1.217e-02	0.180	-2.902	NOSTRIN	nitric oxide synthase trafficker	2	169367352, 169367398	AK002203	115677	2q24.3-q31.1	Hs.189780	9	protein binding cytoplasm cytoskeleton plasma membrane plasma membrane endocytosis cytoplasmic vesicle
223535_at	-0.387	6.031	-2.845	1.217e-02	0.180	-2.902	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	5	-102912454	AL136592	83594	5q21.2	Hs.434289	9	NAD+ diphosphatase activity magnesium ion binding nucleus peroxisome hydrolase activity manganese ion binding	Nicotinate and nicotinamide metabolism
231112_at	-0.257	4.803	-2.844	1.217e-02	0.180	-2.902	SNRPE	small nuclear ribonucleoprotein polypeptide E	1	202097362	AU144102	6635	1q32	Hs.334612 Hs.654418	43	spliceosome assembly spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytosol RNA splicing small nuclear ribonucleoprotein complex
242944_at	0.190	6.214	2.844	1.217e-02	0.180	-2.902	FAM83A	family with sequence similarity 83, member A	8	124263932, 124263932	BG438092	84985	8q24.13	Hs.379821	4
204265_s_at	0.330	5.870	2.844	1.217e-02	0.180	-2.902	GPSM3	G-protein signaling modulator 3 (AGS3-like, C. elegans)	6	-32266520, -3565727, -3373507	NM_022107	63940	6p21.3	Hs.520046	7	molecular_function GTPase activator activity protein binding cellular_component cytoplasm signal transduction biological_process
203446_s_at	-0.302	5.961	-2.844	1.218e-02	0.180	-2.902	OCRL	oculocerebrorenal syndrome of Lowe	X	128501932	NM_000276	4952	Xq25-q26.1	Hs.126357	36	inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity intracellular Golgi stack Golgi-associated vesicle lipid metabolic process signal transduction hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
213112_s_at	-0.375	6.377	-2.844	1.218e-02	0.180	-2.902	SQSTM1	sequestosome 1	5	179165993, 179166608, 179180447	N30649	8878	5q35	Hs.437277	100	protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
223269_at	-0.281	8.630	-2.844	1.219e-02	0.180	-2.903	POLR3GL	polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like	1	-144167592	BC004355	84265	1q21.1	Hs.591456	2		Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
238975_at	0.341	4.701	2.844	1.219e-02	0.180	-2.903	MMAB	methylmalonic aciduria (cobalamin deficiency) cblB type	12	-108475903	AI671390	326625	12q24	Hs.12106	16	nucleotide binding ATP binding mitochondrion cob(I)yrinic acid a,c-diamide adenosyltransferase activity cobalamin biosynthetic process transferase activity	Porphyrin and chlorophyll metabolism Metabolic pathways
209573_s_at	0.270	5.840	2.843	1.220e-02	0.180	-2.904	C18orf1	chromosome 18 open reading frame 1	18	13208785, 13601664, 13610866	AW008505	753	18p11.2	Hs.149363	9	molecular_function plasma membrane biological_process integral to membrane
223070_at	-0.455	10.146	-2.843	1.220e-02	0.180	-2.904	SELK	selenoprotein K	3	-53894265	AF085359	58515	3p21.31	Hs.58471 Hs.640242	7	endoplasmic reticulum response to oxidative stress selenium binding
205757_at	0.229	4.339	2.843	1.221e-02	0.181	-2.904	ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	14	-73502935	NM_001249	957	14q24	Hs.131555	14	magnesium ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen hydrolase activity nucleoside-diphosphatase activity	Purine metabolism Pyrimidine metabolism
206061_s_at	-0.522	5.748	-2.843	1.221e-02	0.181	-2.904	DICER1	dicer 1, ribonuclease type III	14	-94622317, -94622317	NM_030621	23405	14q32.13	Hs.87889	63	nucleotide binding magnesium ion binding angiogenesis double-stranded RNA binding helicase activity endonuclease activity ribonuclease III activity protein binding ATP binding intracellular cytoplasm RNA processing ATP-dependent helicase activity RNA-induced silencing complex hydrolase activity stem cell maintenance manganese ion binding lung development RNA interference, production of siRNA RNA interference, targeting of mRNA for destruction gene silencing by RNA pre-microRNA processing embryonic hindlimb morphogenesis branching morphogenesis of a tube
240110_at	0.506	4.433	2.843	1.222e-02	0.181	-2.905	HMGCS2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	1	-120092525	AI090874	3158	1p13-p12	Hs.59889	13	hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity mitochondrion mitochondrial inner membrane mitochondrial matrix cholesterol biosynthetic process response to nutrient metabolic process isoprenoid biosynthetic process transferase activity response to drug response to peptide hormone stimulus	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
200850_s_at	-0.468	8.902	-2.843	1.222e-02	0.181	-2.906	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	NM_006621	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
213453_x_at	-0.235	13.645	-2.842	1.222e-02	0.181	-2.906	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	BF689355	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
235003_at	-0.446	4.461	-2.842	1.223e-02	0.181	-2.906	UHMK1	U2AF homology motif (UHM) kinase 1	1	160734278	AI249980	127933	1q23.3	Hs.127310	13	nucleotide binding RNA binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm cell cycle arrest transferase activity peptidyl-serine phosphorylation protein amino acid autophosphorylation regulation of protein export from nucleus
209377_s_at	-0.355	10.558	-2.842	1.223e-02	0.181	-2.906	HMGN3	high mobility group nucleosomal binding domain 3	6	-79967680	AF274949	9324	6q14.1	Hs.77558	9	chromatin DNA binding protein binding nucleus biological_process thyroid hormone receptor binding
212067_s_at	0.678	6.938	2.842	1.224e-02	0.181	-2.907	C1R	complement component 1, r subcomponent	12	-7057769	AL573058	715	12p13	Hs.524224	37	serine-type endopeptidase activity calcium ion binding extracellular region extracellular region proteolysis complement activation, classical pathway peptidase activity innate immune response	Complement and coagulation cascades Systemic lupus erythematosus
205398_s_at	0.262	6.763	2.841	1.225e-02	0.181	-2.908	SMAD3	SMAD family member 3	15	65145248, 65205107, 65217412, 65245546	NM_005902	4088	15q22.33	Hs.714621 Hs.718953	271	negative regulation of transcription from RNA polymerase II promoter response to hypoxia mesoderm formation osteoblast development double-stranded DNA binding transcription factor activity transforming growth factor beta receptor binding collagen binding intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol plasma membrane induction of apoptosis activation of caspase activity cell cycle arrest SMAD protein complex assembly transcription factor binding positive regulation of epithelial to mesenchymal transition promoter binding transport accessory protein activity regulation of striated muscle tissue development transcription activator activity regulation of transforming growth factor beta receptor signaling pathway evasion of host defenses by virus negative regulation of cell growth transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding regulation of transforming growth factor-beta2 production wound healing T cell activation protein homodimerization activity positive regulation of transcription factor import into nucleus receptor complex cell-cell junction organization negative regulation of osteoblast differentiation negative regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of epithelial cell proliferation regulation of immune response regulation of binding co-SMAD binding R-SMAD binding	Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia
1555962_at	0.279	3.339	2.841	1.225e-02	0.181	-2.908	B3GNT7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	2	231968578	CA503291	93010	2q37.1	Hs.299329	4	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups	Keratan sulfate biosynthesis Metabolic pathways
219804_at	-0.512	10.192	-2.841	1.226e-02	0.181	-2.909	SYNPO2L	synaptopodin 2-like	10	-75074649, -75074649	NM_024875	79933	10q22.2	Hs.645273	4	actin binding protein binding cytoplasm cytoskeleton
223880_x_at	-0.463	10.902	-2.841	1.227e-02	0.181	-2.909	C20orf24	chromosome 20 open reading frame 24	20	34667580, 34667605	BC004446	55969	20q11.23	Hs.584985	7	molecular_function protein binding cellular_component biological_process
218872_at	0.280	5.610	2.840	1.227e-02	0.181	-2.909	TESC	tescalcin	12	-115961110	NM_017899	54997	12q24.22	Hs.525709	8	magnesium ion binding ruffle calcium ion binding protein binding nucleus cytoplasm phosphatase inhibitor activity lamellipodium
221029_s_at	0.239	4.037	2.840	1.227e-02	0.181	-2.909	WNT5B	wingless-type MMTV integration site family, member 5B	12	1596482, 1608672	NM_030775	81029	12p13.3	Hs.306051	11	signal transducer activity extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
1561414_at	-0.233	2.143	-2.840	1.228e-02	0.181	-2.910	LOC401497	similar to PRO2738	9		BC022036	401497	9p21.1	Hs.680131	1
238117_at	0.432	3.644	2.840	1.228e-02	0.181	-2.910	PPOX	protoporphyrinogen oxidase	1	159402804	AW615133	5498	1q22	Hs.517373	32	oxygen-dependent protoporphyrinogen oxidase activity oxygen-dependent protoporphyrinogen oxidase activity mitochondrion mitochondrial intermembrane space heme biosynthetic process electron carrier activity membrane oxidoreductase activity intrinsic to mitochondrial inner membrane FAD binding oxidation reduction	Porphyrin and chlorophyll metabolism Metabolic pathways
208911_s_at	0.280	10.061	2.840	1.228e-02	0.181	-2.910	PDHB	pyruvate dehydrogenase (lipoamide) beta	3	-58388393	M34055	5162	3p21.1-p14.2	Hs.161357	27	pyruvate dehydrogenase (acetyl-transferring) activity mitochondrion mitochondrial matrix glycolysis tricarboxylic acid cycle oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
1553351_at	0.329	3.749	2.840	1.228e-02	0.181	-2.910	OTUD7A	OTU domain containing 7A	15	-29562620	NM_130901	161725	15q13.3	Hs.355236	2	DNA binding nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process metal ion binding
229322_at	-0.593	8.239	-2.840	1.229e-02	0.181	-2.911	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	14	-62911107	BF529715	5529	14q23.1	Hs.334868	20	protein phosphatase type 2A complex protein binding cytoplasm signal transduction protein phosphatase type 2A regulator activity intracellular membrane-bounded organelle	Wnt signaling pathway
218871_x_at	-0.451	7.672	-2.840	1.229e-02	0.181	-2.911	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	10	42953939	NM_018590	55454	10q11.21	Hs.657569	6	protein binding Golgi apparatus membrane integral to membrane transferase activity integral to Golgi membrane Golgi cisterna membrane metal ion binding glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Chondroitin sulfate biosynthesis Metabolic pathways
213531_s_at	-0.284	9.506	-2.839	1.232e-02	0.181	-2.913	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	AI040009	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
229570_at	0.271	5.497	2.838	1.232e-02	0.181	-2.913	LAMA5	laminin, alpha 5	20	-60317515	BE219071	3911	20q13.2-q13.3	Hs.473256	61	receptor binding structural molecule activity extracellular region basement membrane laminin-1 complex regulation of cell adhesion regulation of cell migration substrate adhesion-dependent cell spreading laminin-10 complex laminin-11 complex regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
202242_at	-0.477	9.102	-2.838	1.232e-02	0.181	-2.913	TSPAN7	tetraspanin 7	X	38305674	NM_004615	7102	Xp11.4	Hs.441664	18	plasma membrane integral to plasma membrane protein amino acid N-linked glycosylation
211960_s_at	-0.394	8.054	-2.838	1.233e-02	0.181	-2.914	RAB7A	RAB7A, member RAS oncogene family	3	129927668	BG261416	7879	3q21.3	Hs.15738 Hs.716392	64	nucleotide binding GTPase activity protein binding GTP binding cytoplasm lysosome late endosome Golgi apparatus endocytosis small GTPase mediated signal transduction protein transport cytoplasmic vesicle melanosome phagocytic vesicle
204367_at	-0.389	6.088	-2.838	1.233e-02	0.181	-2.914	SP2	Sp2 transcription factor	17	43328514	D28588	6668	17q21.32	Hs.514276	18	DNA binding RNA polymerase II transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter immune response zinc ion binding histone deacetylase binding regulation of transcription metal ion binding
217478_s_at	1.138	5.897	2.838	1.233e-02	0.181	-2.914	HLA-DMA	major histocompatibility complex, class II, DM alpha	6	-33024368, -4297243, -4102463	X76775	3108	6p21.3	Hs.351279	72	nucleotide binding antigen processing and presentation of peptide or polysaccharide antigen via MHC class II protein binding ATP binding intracellular lysosomal membrane multivesicular body plasma membrane protein complex assembly endosome membrane protein transport integral to membrane immunoglobulin mediated immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide binding MHC class I protein binding MHC class II protein complex TAP complex positive thymic T cell selection positive regulation of T cell differentiation positive regulation of immune response chaperone mediated protein folding requiring cofactor	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
209335_at	0.620	8.939	2.838	1.234e-02	0.181	-2.914	DCN	decorin	12	-90063165, -90063165, -90063165	AI281593	1634	12q21.33	Hs.718429	104	protein binding glycosaminoglycan binding extracellular region proteinaceous extracellular matrix organ morphogenesis peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix binding	TGF-beta signaling pathway
202372_at	-0.275	6.772	-2.837	1.235e-02	0.181	-2.915	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	BF240652	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
207688_s_at	-0.534	4.831	-2.837	1.235e-02	0.181	-2.916	INHBC	inhibin, beta C	12	56114809	NM_005538	3626	12q13.1	Hs.632722	12	transforming growth factor beta receptor binding hormone activity extracellular region growth factor activity	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
218300_at	0.259	7.164	2.837	1.235e-02	0.181	-2.916	C16orf53	chromosome 16 open reading frame 53	16	29735028	NM_024516	79447	16p11.2	Hs.702841	7
212205_at	-0.432	9.711	-2.837	1.236e-02	0.181	-2.916	H2AFV	H2A histone family, member V	7	-44839737, -44833012	AA534860	94239	7p13	Hs.488189	12	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
204499_at	-0.486	5.895	-2.837	1.237e-02	0.181	-2.916	AGTPBP1	ATP/GTP binding protein 1	9	-87351273	AB028958	23287	9q21.33	Hs.494321	7	metallocarboxypeptidase activity binding nucleus cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding cerebellar Purkinje cell differentiation neurotransmitter metabolic process metal ion binding neuromuscular process
226214_at	-0.371	8.802	-2.836	1.237e-02	0.181	-2.917	GDE1	glycerophosphodiester phosphodiesterase 1	16	-19420515	BE677894	51573	16p12-p11.2	Hs.512607	8	magnesium ion binding cytoplasm glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity glycerophosphoinositol glycerophosphodiesterase activity	Glycerophospholipid metabolism
217655_at	0.250	3.262	2.836	1.237e-02	0.181	-2.917	LOC100127972	hypothetical LOC100127972	19		BE552409	100127972	19q13.12	Hs.710764 Hs.716895	1
203865_s_at	0.404	6.535	2.836	1.238e-02	0.181	-2.917	ADARB1	adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)	21	45318920	NM_015833	104	21q22.3	Hs.474018	35	double-stranded RNA binding adenosine deaminase activity intracellular mRNA processing zinc ion binding hydrolase activity metal ion binding
235798_at	-0.578	6.282	-2.836	1.238e-02	0.181	-2.917	TMEM170B	transmembrane protein 170B	6	11646496	BE671123	100113407	6p24.2	Hs.146317	1	membrane integral to membrane
204578_at	0.286	6.207	2.836	1.239e-02	0.181	-2.918	HISPPD2A	histidine acid phosphatase domain containing 2A	15	-41612952	NM_014659	9677	15q15.3	Hs.156814	8	nucleotide binding inositol 1,3,4,5,6-pentakisphosphate kinase activity inositol hexakisphosphate 5-kinase activity acid phosphatase activity ATP binding cytoplasm cytosol inositol metabolic process kinase activity transferase activity diphosphoinositol-pentakisphosphate kinase activity
202173_s_at	-0.511	7.642	-2.835	1.240e-02	0.181	-2.919	VEZF1	vascular endothelial zinc finger 1	17	-53403908	NM_007146	7716	17q22	Hs.463569	3	angiogenesis endothelial cell development DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter cellular defense response zinc ion binding regulation of transcription metal ion binding
231853_at	-0.454	4.832	-2.835	1.241e-02	0.181	-2.920	TUBD1	tubulin, delta 1	17	-55291632	AK022771	51174	17q23.1	Hs.463638	7	nucleotide binding GTPase activity structural molecule activity GTP binding nucleus cytoplasm centriole microtubule microtubule-based movement multicellular organismal development spermatogenesis cell differentiation protein complex protein polymerization
218604_at	-0.316	7.313	-2.835	1.241e-02	0.181	-2.920	LEMD3	LEM domain containing 3	12	63849637	NM_014319	23592	12q14	Hs.718513	13	nucleotide binding DNA binding membrane fraction nucleus nuclear envelope integral to nuclear inner membrane membrane integral to membrane
209659_s_at	-0.331	8.563	-2.835	1.242e-02	0.181	-2.920	CDC16	cell division cycle 16 homolog (S. cerevisiae)	13	114018463	AF164598	8881	13q34	Hs.374127	32	binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
219631_at	-0.412	5.780	-2.834	1.242e-02	0.181	-2.921	LRP12	low density lipoprotein-related protein 12	8	-105570642	NM_024937	29967	8q22.2-q23.1	Hs.600630	8	receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth
203864_s_at	-0.642	10.963	-2.834	1.243e-02	0.181	-2.921	ACTN2	actinin, alpha 2	1	234916392	NM_001103	88	1q42-q43	Hs.498178	57	actin binding integrin binding calcium ion binding nucleolus cytoplasm cytoskeleton actin filament focal adhesion muscle contraction cell adhesion structural constituent of muscle Z disc microspike assembly filopodium thyroid hormone receptor coactivator activity pseudopodium titin binding identical protein binding regulation of apoptosis dendritic spine protein dimerization activity focal adhesion formation protein homotetramerization ZASP binding FATZ 1 binding titin Z domain binding	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
204813_at	0.380	5.818	2.834	1.243e-02	0.181	-2.921	MAPK10	mitogen-activated protein kinase 10	4	-87156655, -87156655, -87156655, -87156655	NM_002753	5602	4q22.1-q23	Hs.125503	54	nucleotide binding protein serine/threonine kinase activity JUN kinase activity MAP kinase activity MAP kinase kinase activity ATP binding cytoplasm protein amino acid phosphorylation signal transduction JNK cascade transferase activity	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Pancreatic cancer
214365_at	0.322	13.128	2.833	1.246e-02	0.182	-2.923	TPM3	tropomyosin 3	1	-152400913, -152394403	X04201	7170	1q21.2	Hs.535581 Hs.644306 Hs.654421	66	molecular_function actin binding protein binding cytoplasm cytoskeleton cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction	Cardiac muscle contraction Pathways in cancer Thyroid cancer Hypertrophic cardiomyopathy (HCM)
225594_at	-0.519	6.589	-2.832	1.247e-02	0.182	-2.924	CREBZF	CREB/ATF bZIP transcription factor	11	-85046257	AL038866	58487	11q14	Hs.535319 Hs.595940 Hs.714910	12	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent response to virus negative regulation of transcription specific transcriptional repressor activity sequence-specific DNA binding negative regulation of gene expression, epigenetic regulation of transcription factor activity
201052_s_at	0.395	7.913	2.832	1.248e-02	0.182	-2.925	PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	20	1041905, 1047239	BG029917	9491	20p13	Hs.471917	45	protein binding cytosol proteasome core complex ubiquitin-dependent protein catabolic process proteasome inhibitor activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
239533_at	-0.414	6.111	-2.832	1.249e-02	0.182	-2.925	GPR155	G protein-coupled receptor 155	2	-175004620	AI970061	151556	2q31.1	Hs.516604	9	intracellular signaling cascade membrane integral to membrane
219827_at	-0.922	8.156	-2.832	1.249e-02	0.182	-2.926	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	11	-73391459, -73388975	NM_003356	7352	11q13	Hs.101337 Hs.621879	108	response to superoxide response to hypoxia transporter activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process transport mitochondrial transport respiratory gaseous exchange proton transport membrane integral to membrane oxidative phosphorylation uncoupler activity
211529_x_at	0.434	8.598	2.831	1.251e-02	0.182	-2.927	HLA-G	major histocompatibility complex, class I, G	6	29902734, 1247153, 1049287	M90684	3135	6p21.3	Hs.512152	316	antigen processing and presentation of peptide antigen via MHC class I immune response cellular defense response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
224452_s_at	-0.630	9.919	-2.831	1.252e-02	0.182	-2.928	C7orf70	chromosome 7 open reading frame 70	7	-6335564	BC006110	84792	7p22.1	Hs.696146	4	nucleus
229405_at	0.308	5.161	2.830	1.253e-02	0.182	-2.928	KIF7	kinesin family member 7	15	-87972204	BF515033	374654	15q26.1	Hs.513134	5	nucleotide binding microtubule motor activity ATP binding microtubule-based movement
226335_at	-0.478	9.065	-2.830	1.254e-02	0.182	-2.929	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	X	-20077949	BG498334	6197	Xp22.2-p22.1	Hs.445387	89	nucleotide binding magnesium ion binding skeletal system development protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleoplasm cytoplasm protein amino acid phosphorylation signal transduction protein kinase cascade central nervous system development transferase activity	MAPK signaling pathway mTOR signaling pathway Long-term potentiation Neurotrophin signaling pathway
200639_s_at	0.276	8.079	2.830	1.254e-02	0.182	-2.929	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	8	-101999980, -101999980, -101999980, -101999980, -101999980	NM_003406	7534	8q23.1	Hs.492407 Hs.594673	169	nucleus cytoplasm mitochondrion protein targeting anti-apoptosis signal transduction transcription factor binding protein domain specific binding melanosome	Cell cycle Neurotrophin signaling pathway Pathogenic Escherichia coli infection - EHEC
222896_at	-0.535	9.914	-2.829	1.255e-02	0.182	-2.930	TMEM38A	transmembrane protein 38A	19	16632937	AA196034	79041	19p13.11	Hs.436068	4	potassium channel activity nucleus ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane
243582_at	-0.952	6.632	-2.829	1.257e-02	0.183	-2.931	SH3RF2	SH3 domain containing ring finger 2	5	145296318	AW082633	153769	5q32	Hs.443728	4	protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
200676_s_at	-0.438	6.244	-2.829	1.257e-02	0.183	-2.931	UBE2L3	ubiquitin-conjugating enzyme E2L 3	22	20251956	NM_003347	7332	22q11.21	Hs.108104 Hs.603229 Hs.715088	38	ubiquitin ligase complex nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity enzyme binding regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
1558662_s_at	0.212	2.853	2.828	1.259e-02	0.183	-2.933	BANK1	B-cell scaffold protein with ankyrin repeats 1	4	102930786, 102954005	BG200452	55024	4q24	Hs.480400	11	B cell activation
203906_at	0.297	7.755	2.828	1.259e-02	0.183	-2.933	IQSEC1	IQ motif and Sec7 domain 1	3	-12913718, -12913718	AI652645	9922	3p25.2	Hs.475506	10	ARF guanyl-nucleotide exchange factor activity intracellular nucleus cytoplasm regulation of ARF protein signal transduction	Endocytosis
206416_at	0.320	6.929	2.828	1.259e-02	0.183	-2.933	ZNF205	zinc finger protein 205	16	3102563	NM_003456	7755	16p13.3	Hs.592088	5	DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231812_x_at	-0.268	7.365	-2.828	1.259e-02	0.183	-2.933	PHAX	phosphorylated adaptor for RNA export	5	125964531	AK023255	51808	5q23.2	Hs.555731 Hs.719165	10	spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol snRNA export from nucleus Cajal body protein transport
238601_at	-0.805	8.441	-2.827	1.260e-02	0.183	-2.934	PHKB	phosphorylase kinase, beta	16	46052710	AI798207	5257	16q12-q13	Hs.78060	13	catalytic activity calmodulin binding plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy	Calcium signaling pathway Insulin signaling pathway
244477_at	0.310	5.739	2.827	1.260e-02	0.183	-2.934	SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	16	55456619	AW292635	6559	16q13	Hs.669115	52	transporter activity membrane fraction integral to plasma membrane ion transport sodium ion transport chloride transport symporter activity sodium:chloride symporter activity membrane apical plasma membrane sodium ion binding
201170_s_at	-1.718	8.515	-2.827	1.261e-02	0.183	-2.935	BHLHE40	basic helix-loop-helix family, member e40	3	4996096	NM_003670	8553	3p26	Hs.719093	26	transcription factor activity protein binding nucleus entrainment of circadian clock transcription repressor activity negative regulation of transcription, DNA-dependent regulation of neuronal synaptic plasticity	Circadian rhythm - mammal
238176_at	-0.518	4.006	-2.826	1.263e-02	0.183	-2.935	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	4	160408447	T86196	9693	4q32.1	Hs.113912	14	MAPKKK cascade signal transducer activity guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular plasma membrane integral to plasma membrane Rap guanyl-nucleotide exchange factor activity cAMP-mediated signaling diacylglycerol binding Rap GTPase activator activity regulation of small GTPase mediated signal transduction	MAPK signaling pathway
211023_at	0.234	11.771	2.826	1.263e-02	0.183	-2.936	PDHB	pyruvate dehydrogenase (lipoamide) beta	3	-58388393	AL117618	5162	3p21.1-p14.2	Hs.161357	27	pyruvate dehydrogenase (acetyl-transferring) activity mitochondrion mitochondrial matrix glycolysis tricarboxylic acid cycle oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Citrate cycle (TCA cycle) Valine, leucine and isoleucine biosynthesis Pyruvate metabolism Butanoate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
202512_s_at	-0.423	6.611	-2.826	1.264e-02	0.183	-2.936	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	6	-106739044	NM_004849	9474	6q21	Hs.486063	30	autophagic vacuole formation protein binding cytoplasm autophagic vacuole autophagy apoptosis pre-autophagosomal structure membrane post-translational protein modification	Regulation of autophagy RIG-I-like receptor signaling pathway
234984_at	-0.771	8.407	-2.826	1.265e-02	0.183	-2.937	NEDD1	neural precursor cell expressed, developmentally down-regulated 1	12	95825131, 95825374	AA236927	121441	12q23.1	Hs.270084	10	pericentriolar material spindle pole cytoplasm centriole microtubule basal body cell cycle mitosis apical part of cell cell division
212623_at	-0.423	6.618	-2.825	1.266e-02	0.183	-2.938	TMEM41B	transmembrane protein 41B	11	-9258777	AU153138	440026	11p15.4	Hs.594563	4	membrane integral to membrane
226909_at	-0.306	7.200	-2.825	1.266e-02	0.183	-2.938	ZNF518B	zinc finger protein 518B	4	-10050601	AW270138	85460	4p16.1	Hs.455089	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1552344_s_at	-0.634	6.052	-2.825	1.267e-02	0.183	-2.938	CNOT7	CCR4-NOT transcription complex, subunit 7	8	-17133392, -17131110	NM_054026	29883	8p22-p21.3	Hs.645009 Hs.719129	19	nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter	RNA degradation
217897_at	0.270	6.983	2.825	1.267e-02	0.183	-2.938	FXYD6	FXYD domain containing ion transport regulator 6	11	-117212902	NM_022003	53826	11q23.3	Hs.713034	14	molecular_function ion channel activity extracellular space plasma membrane ion transport biological_process integral to membrane
212342_at	-0.518	5.669	-2.825	1.267e-02	0.183	-2.939	YIPF6	Yip1 domain family, member 6	X	67635610	BG500611	286451	Xq12	Hs.700646 Hs.82719	10	endoplasmic reticulum membrane integral to membrane
220926_s_at	-0.599	5.557	-2.824	1.269e-02	0.183	-2.940	EDEM3	ER degradation enhancer, mannosidase alpha-like 3	1	-182926247	NM_025191	80267	1q24-q25	Hs.523811	10	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen response to unfolded protein membrane
223985_at	-0.410	3.084	-2.824	1.269e-02	0.183	-2.940	FSD1L	fibronectin type III and SPRY domain containing 1-like	9	107250135, 107250135, 107250145	AF316830	83856	9q31	Hs.136901	4	molecular_function cellular_component biological_process
213776_at	-0.388	6.448	-2.824	1.270e-02	0.183	-2.941	LOC157562	hypothetical protein LOC157562	8		AA583336	157562	8q22.3	Hs.27371
239426_at	-0.585	4.922	-2.823	1.270e-02	0.183	-2.941	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8	9	129199285	AA812746	29988	9q33.3	Hs.179522	7	response to hypoxia transporter activity glucose transmembrane transporter activity glucose binding plasma membrane integral to plasma membrane carbohydrate metabolic process insulin receptor signaling pathway carbohydrate transport glucose transport substrate-specific transmembrane transporter activity cytoplasmic vesicle intracellular membrane-bounded organelle transmembrane transport
228381_at	0.735	4.616	2.823	1.270e-02	0.183	-2.941	ATF7IP2	activating transcription factor 7 interacting protein 2	16	10430225	AV716964	80063	16p13.13	Hs.513343	6	nucleus regulation of transcription
225921_at	-0.702	7.246	-2.823	1.271e-02	0.183	-2.942	NIN	ninein (GSK3B interacting protein)	14	-50263700, -50262296, -50262296, -50256230	AL359571	51199	14q22.1	Hs.310429	23	nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization
226043_at	0.233	6.571	2.823	1.272e-02	0.183	-2.942	GPSM1	G-protein signaling modulator 1 (AGS3-like, C. elegans)	9	138341752, 138341752, 138367329	AI242661	26086	9q34.3	Hs.239370	14	GTPase activator activity binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane signal transduction multicellular organismal development nervous system development cell differentiation
225804_at	0.462	6.474	2.823	1.272e-02	0.183	-2.942	CYB5D2	cytochrome b5 domain containing 2	17	3993210	BE044480	124936	17p13.2	Hs.513871	2	membrane integral to membrane heme binding
207795_s_at	0.260	4.010	2.822	1.273e-02	0.183	-2.943	KLRD1	killer cell lectin-like receptor subfamily D, member 1	12	10348316, 10351683	AB009597	3824	12p13	Hs.562457	46	transmembrane receptor activity binding sugar binding plasma membrane plasma membrane cell surface receptor linked signal transduction integral to membrane	Antigen processing and presentation Natural killer cell mediated cytotoxicity Graft-versus-host disease
225827_at	-0.369	6.689	-2.822	1.273e-02	0.183	-2.943	EIF2C2	eukaryotic translation initiation factor 2C, 2	8	-141610445	AI832074	27161	8q24	Hs.449415	47	RNA 7-methylguanosine cap binding cytoplasmic mRNA processing body translation initiation factor activity endonuclease activity protein binding nucleus cytoplasm mRNA cap binding complex regulation of translation RNA-induced silencing complex hydrolase activity gene silencing by RNA pre-microRNA processing micro-ribonucleoprotein complex siRNA binding gene silencing by miRNA, negative regulation of translation gene silencing by miRNA, negative regulation of translation gene silencing by miRNA, mRNA cleavage gene silencing by miRNA, mRNA cleavage regulation of transcription negative regulation of translational initiation metal ion binding endoribonuclease activity, cleaving siRNA-paired mRNA
219603_s_at	0.353	4.885	2.822	1.274e-02	0.183	-2.944	ZNF226	zinc finger protein 226	19	49361088, 49361088, 49361096, 49361156	NM_015919	7769	19q13.2	Hs.145956	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201528_at	-0.476	8.704	-2.822	1.275e-02	0.183	-2.944	RPA1	replication protein A1, 70kDa	17	1680022	BG398414	6117	17p13.3	Hs.461925 Hs.595562	106	nucleotide-excision repair, DNA damage removal double-strand break repair via homologous recombination condensed nuclear chromosome male germ cell nucleus in utero embryonic development DNA binding chromatin binding single-stranded DNA binding protein binding nucleus nucleoplasm DNA replication factor A complex cytoplasm cytoskeleton DNA-dependent DNA replication DNA repair nucleotide-excision repair, DNA gap filling DNA recombination meiosis zinc ion binding positive regulation of cell proliferation PML body hemopoiesis metal ion binding homeostasis of number of cells within a tissue chromosome organization	DNA replication Nucleotide excision repair Mismatch repair Homologous recombination
210875_s_at	-0.709	6.856	-2.822	1.275e-02	0.183	-2.944	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	U12170	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
201058_s_at	0.648	5.795	2.821	1.276e-02	0.183	-2.945	MYL9	myosin, light chain 9, regulatory	20	34603310	NM_006097	10398	20q11.23	Hs.504687	8	motor activity calcium ion binding muscle myosin complex regulation of muscle contraction structural constituent of muscle myosin complex	Vascular smooth muscle contraction Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
1554258_a_at	-0.316	5.286	-2.821	1.276e-02	0.184	-2.945	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	8	67096344	AF368276	85479	8q13.1	Hs.491885	3	protein folding membrane heat shock protein binding unfolded protein binding
1554868_s_at	-0.715	7.913	-2.820	1.278e-02	0.184	-2.947	PCNP	PEST proteolytic signal containing nuclear protein	3	102775731	BC013916	57092	3q12.3	Hs.545311 Hs.654949	6	protein binding nucleus cell cycle protein ubiquitination proteasomal ubiquitin-dependent protein catabolic process
223743_s_at	0.518	7.087	2.819	1.281e-02	0.184	-2.948	MRPL4	mitochondrial ribosomal protein L4	19	10223639, 10223639	BC000756	51073	19p13.2	Hs.279652	10	structural constituent of ribosome intracellular mitochondrion ribosome translation
212288_at	-0.350	7.949	-2.819	1.281e-02	0.184	-2.949	FNBP1	formin binding protein 1	9	-131689286	AB011126	23048	9q34	Hs.189409	25	cytoplasm lysosome cytoskeleton plasma membrane cell cortex endocytosis lipid binding cytoplasmic vesicle identical protein binding
225136_at	0.562	6.160	2.819	1.281e-02	0.184	-2.949	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	8	38877909	BF968578	59339	8p11.22	Hs.369123	4	phospholipid binding phosphatidylinositol binding cellular_component nucleus cytoplasm plasma membrane biological_process
224558_s_at	-0.527	9.293	-2.818	1.283e-02	0.184	-2.950	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11	65021808	AI446756	378938	11q13.1	Hs.642877 Hs.714394	8
206682_at	0.412	4.632	2.818	1.283e-02	0.184	-2.950	CLEC10A	C-type lectin domain family 10, member A	17	-6918579	NM_006344	10462	17p13.1	Hs.54403	4	binding sugar binding plasma membrane endocytosis immune response integral to membrane
208744_x_at	-0.300	6.312	-2.818	1.284e-02	0.184	-2.951	HSPH1	heat shock 105kDa/110kDa protein 1	13	-30608762	BG403660	10808	13q12.3	Hs.36927	25	nucleotide binding ATP binding cytoplasm response to unfolded protein
201461_s_at	-0.271	2.922	-2.818	1.284e-02	0.184	-2.951	MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	1	204924911	NM_004759	9261	1q32	Hs.643566 Hs.713747	61	MAPKKK cascade nucleotide binding protein serine/threonine kinase activity signal transducer activity protein binding ATP binding nucleus cytosol protein amino acid phosphorylation intracellular signaling cascade Ras protein signal transduction transferase activity	MAPK signaling pathway VEGF signaling pathway Neurotrophin signaling pathway
200968_s_at	0.452	6.890	2.818	1.285e-02	0.184	-2.951	PPIB	peptidylprolyl isomerase B (cyclophilin B)	15	-62235066	NM_000942	5479	15q21-q22	Hs.434937	41	peptidyl-prolyl cis-trans isomerase activity endoplasmic reticulum endoplasmic reticulum lumen protein folding isomerase activity peptide binding melanosome unfolded protein binding
200059_s_at	-0.353	10.457	-2.818	1.285e-02	0.184	-2.951	RHOA	ras homolog gene family, member A	3	-49371582	BC001360	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
208907_s_at	0.358	9.821	2.818	1.285e-02	0.184	-2.952	MRPS18B	mitochondrial ribosomal protein S18B	6	30693464, 2034045, 1832339	BC005373	28973	6p21.3	Hs.655329	11	structural constituent of ribosome intracellular mitochondrion mitochondrial small ribosomal subunit ribosome translation
217811_at	-0.290	8.433	-2.817	1.286e-02	0.184	-2.952	SELT	selenoprotein T	3	151803755	NM_016275	51714	3q25.1	Hs.369052	9	selenocysteine incorporation selenium binding cell redox homeostasis
232604_at	0.314	5.571	2.817	1.286e-02	0.184	-2.952	ZNF541	zinc finger protein 541	19	-52715759	AL136846	84215	19q13.33	Hs.14161	3	DNA binding intracellular nucleus multicellular organismal development spermatogenesis zinc ion binding cell differentiation regulation of transcription metal ion binding
216100_s_at	-0.796	4.756	-2.817	1.286e-02	0.184	-2.952	TOR1AIP1	torsin A interacting protein 1	1	178118042	BG289527	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
221808_at	-0.352	7.489	-2.817	1.287e-02	0.184	-2.953	RAB9A	RAB9A, member RAS oncogene family	X	13617261	NM_004251	9367	Xp22.2	Hs.495704	24	Golgi membrane nucleotide binding GTPase activity protein binding GTP binding lysosome late endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport
214263_x_at	-0.417	7.718	-2.817	1.288e-02	0.184	-2.953	POLR2C	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	16	56054051	AI192781	5432	16q13-q21	Hs.79402	89	nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm cytoplasm transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
202843_at	-0.528	6.201	-2.816	1.288e-02	0.184	-2.954	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	7	107997591	NM_012328	4189	14q24.2-q24.3 7q31	Hs.6790	16	nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding
235634_at	0.283	5.179	2.816	1.289e-02	0.184	-2.954	PURG	purine-rich element binding protein G	8	-31007898, -30972862	BE503391	29942	8p11	Hs.373778	3	DNA binding nucleus
221374_at	-0.279	4.109	-2.816	1.290e-02	0.184	-2.955	FGF16	fibroblast growth factor 16	X	76596302	NM_003868	8823	Xq13	Hs.666364	9	extracellular region extracellular region extracellular space signal transduction cell-cell signaling growth factor activity metabolic process fibroblast growth factor receptor signaling pathway response to temperature stimulus organ morphogenesis	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
223342_at	-0.569	7.996	-2.815	1.293e-02	0.184	-2.957	RRM2B	ribonucleotide reductase M2 B (TP53 inducible)	8	-103285906	AB036063	50484	8q23.1	Hs.512592	29	kidney development renal system process ribonucleoside-diphosphate reductase activity iron ion binding nucleus cytoplasm DNA replication mitochondrial DNA replication DNA repair induction of apoptosis response to DNA damage stimulus response to oxidative stress deoxyribonucleoside diphosphate metabolic process deoxyribonucleoside triphosphate metabolic process deoxyribonucleotide biosynthetic process oxidoreductase activity oxidation reduction	Purine metabolism Pyrimidine metabolism Glutathione metabolism Metabolic pathways p53 signaling pathway
208870_x_at	0.364	11.900	2.814	1.294e-02	0.185	-2.958	ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	10	7870098	BC000931	509	10p15.1	Hs.271135	18	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) mitochondrion mitochondrion mitochondrial matrix ion transport ATP synthesis coupled proton transport proton transport membrane ATPase activity ATPase activity hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
231437_at	0.240	4.973	2.814	1.295e-02	0.185	-2.958	SLC35D2	solute carrier family 35, member D2	9	-98122809	AA693722	11046	9q22.32	Hs.494556	6	nucleotide-sugar transmembrane transporter activity cellular_component Golgi apparatus biological_process carbohydrate transport membrane integral to membrane
235233_s_at	-0.442	6.172	-2.813	1.296e-02	0.185	-2.959	GMEB1	glucocorticoid modulatory element binding protein 1	1	28867830, 28867830	AI061377	10691	1p35.3	Hs.632373	18	DNA binding transcription coactivator activity binding nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding
206090_s_at	0.352	4.538	2.813	1.297e-02	0.185	-2.960	DISC1	disrupted in schizophrenia 1	1	229829183, 229829183, 229829183	NM_018662	27185	1q42.1	Hs.13318	91	protein binding cellular_component cytoplasm centrosome cytoskeleton microtubule biological_process
216988_s_at	-0.708	9.541	-2.813	1.297e-02	0.185	-2.960	PTP4A2	protein tyrosine phosphatase type IVA, member 2	1	-32146379	L48722	8073	1p35	Hs.470477 Hs.712749 Hs.713025	21	prenylated protein tyrosine phosphatase activity protein binding cytoplasm early endosome plasma membrane protein amino acid dephosphorylation hydrolase activity
200601_at	0.335	6.904	2.813	1.298e-02	0.185	-2.960	ACTN4	actinin, alpha 4	19	43830166	U48734	81	19q13	Hs.270291	64	response to hypoxia stress fiber nucleoside binding integrin binding calcium ion binding nucleus nucleolus cytoplasm protein transport cortical cytoskeleton pseudopodium positive regulation of sodium:hydrogen antiporter activity protein homodimerization activity regulation of apoptosis protein complex protein N-terminus binding perinuclear region of cytoplasm positive regulation of pinocytosis actin filament binding actin filament bundle formation negative regulation of cell motion positive regulation of cell motion positive regulation of cell motion	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
37425_g_at	0.293	5.564	2.813	1.299e-02	0.185	-2.961	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AB029343	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
229666_s_at	0.399	5.679	2.812	1.299e-02	0.185	-2.961	CSTF3	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	11	-33119552, -33062705	AI653037	1479	11p13	Hs.44402	15	nuclear mRNA splicing, via spliceosome RNA binding protein binding intracellular nucleus mRNA polyadenylation mRNA cleavage
221193_s_at	-0.430	6.599	-2.812	1.300e-02	0.185	-2.962	ZCCHC10	zinc finger, CCHC domain containing 10	5	-132360575	NM_017665	54819	5q31.1	Hs.29700	5	nucleic acid binding zinc ion binding metal ion binding
229963_at	0.357	3.927	2.812	1.300e-02	0.185	-2.962	BEX5	brain expressed, X-linked 5	X	-101295335, -101295335	AV726956	340542	Xq22.1	Hs.47209	5	cytoplasm
209295_at	0.601	6.131	2.812	1.301e-02	0.185	-2.962	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	8	-22933592	AF016266	8795	8p22-p21	Hs.521456	133	receptor activity plasma membrane activation of caspase activity cell surface receptor linked signal transduction activation of NF-kappaB-inducing kinase activity induction of apoptosis via death domain receptors activation of pro-apoptotic gene products caspase activator activity integral to membrane regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade TRAIL binding	Cytokine-cytokine receptor interaction p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity
212579_at	-0.657	6.023	-2.812	1.301e-02	0.185	-2.962	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1	18	2645885	AB014550	23347	18p11.32	Hs.8118	6	protein binding ATP binding chromosome chromosome organization
219284_at	-0.507	7.040	-2.812	1.301e-02	0.185	-2.963	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1	3	-123941535	NM_024610	79663	3q21.1	Hs.29169	5	cytoplasm
203740_at	0.410	7.753	2.811	1.301e-02	0.185	-2.963	MPHOSPH6	M-phase phosphoprotein 6	16	-80739267	NM_005792	10200	16q23.3	Hs.344400	11	M phase of mitotic cell cycle protein binding nucleus nucleolus cytoplasm	RNA degradation
222436_s_at	-0.233	8.492	-2.811	1.303e-02	0.185	-2.964	VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	2	-86584063	AF219226	51652	2p24.3-p24.1	Hs.591582	25	protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division	Endocytosis
202804_at	-0.456	7.373	-2.811	1.303e-02	0.185	-2.964	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	16	15950934	AI539710	4363	16p13.1	Hs.709181	163	nucleotide binding transporter activity ATP binding membrane fraction plasma membrane integral to plasma membrane transport hydrolase activity ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances	ABC transporters
221425_s_at	-0.352	8.656	-2.811	1.303e-02	0.185	-2.964	ISCA1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae)	9	-88069282	NM_030940	81689	9q21.33	Hs.449291	9	structural molecule activity iron ion binding mitochondrion iron-sulfur cluster assembly metal ion binding iron-sulfur cluster binding
214014_at	0.296	4.754	2.811	1.304e-02	0.185	-2.965	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	11	64838906	W81196	10435	11q13	Hs.343380	9	opioid peptide activity Rho GTPase activator activity protein binding cytoplasm cytoskeleton plasma membrane actin filament organization regulation of cell shape GTP-Rho binding positive regulation of actin filament polymerization positive regulation of pseudopodium assembly positive regulation of protein complex assembly
201095_at	0.353	5.010	2.810	1.304e-02	0.185	-2.965	DAP	death-associated protein	5	-10732341	NM_004394	1611	5p15.2	Hs.75189	9	apoptosis induction of apoptosis by extracellular signals
226209_at	-0.485	7.066	-2.810	1.304e-02	0.185	-2.965	NDUFV3	NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa	21	43186446	AI129346	4731	21q22.3	Hs.473937	16	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
217830_s_at	-0.328	8.316	-2.810	1.305e-02	0.185	-2.965	NSFL1C	NSFL1 (p97) cofactor (p47)	20	-1370810	AL109658	55968	20p13	Hs.12865	20	protein binding nucleus Golgi apparatus Golgi stack lipid binding
207478_at	-0.281	3.009	-2.810	1.305e-02	0.185	-2.965	PRO2958	hypothetical LOC100128329	2		NM_018546	100128329	2p24.3
226022_at	0.507	8.084	2.810	1.305e-02	0.185	-2.965	SASH1	SAM and SH3 domain containing 1	6	148705421	AU144882	23328	6q24.3	Hs.193133	12	protein binding
220968_s_at	0.287	7.434	2.810	1.305e-02	0.185	-2.965	TSPAN9	tetraspanin 9	12	3056817	NM_031285	10867	12p13.33-p13.32	Hs.504517	8	membrane fraction integral to plasma membrane membrane
201635_s_at	-0.500	9.811	-2.810	1.306e-02	0.185	-2.966	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	AI990766	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
202518_at	-0.333	7.330	-2.809	1.307e-02	0.185	-2.967	BCL7B	B-cell CLL/lymphoma 7B	7	-72588621	NM_001707	9275	7q11.23	Hs.647051	8	actin binding cellular_component biological_process
213625_at	0.245	4.722	2.809	1.307e-02	0.185	-2.967	ZKSCAN4	zinc finger with KRAB and SCAN domains 4	6	-28320468	AW190088	387032	6p21.33-p21.31	Hs.44720	6	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
233977_at	0.341	5.994	2.809	1.308e-02	0.185	-2.967	KIAA1772	KIAA1772	18	17076200	AB051559	80000	18q11.1-q11.2	Hs.149020	4	membrane integral to membrane
225681_at	0.810	5.907	2.809	1.309e-02	0.185	-2.968	CTHRC1	collagen triple helix repeat containing 1	8	104452961	AA584310	115908	8q22.3	Hs.405614	7	extracellular region proteinaceous extracellular matrix
1556864_at	0.243	6.183	2.809	1.309e-02	0.185	-2.968	TCTN1	tectonic family member 1	12	109536262	BC030993	79600	12q24.11	Hs.211511 Hs.694390	5	extracellular region multicellular organismal development
200020_at	-0.429	8.553	-2.808	1.310e-02	0.185	-2.969	TARDBP	TAR DNA binding protein	1	10995265	NM_007375	23435	1p36.22	Hs.300624 Hs.635053 Hs.716809	92	nucleotide binding transcription factor activity RNA binding protein binding nucleus nucleolus transcription from RNA polymerase II promoter mRNA processing mitosis microtubule binding cell death RNA splicing regulation of transcription
228427_at	0.591	4.468	2.808	1.310e-02	0.185	-2.969	FBXO16	F-box protein 16	8	-28341847	BF196856	157574	8p21.1	Hs.659190	5	modification-dependent protein catabolic process
210988_s_at	-0.422	5.587	-2.808	1.310e-02	0.185	-2.969	PRUNE	prune homolog (Drosophila)	1	149247596	AF123538	58497	1q21	Hs.78524	8	inorganic diphosphatase activity protein binding nucleus cytoplasm focal adhesion hydrolase activity cell junction manganese ion binding metal ion binding	Purine metabolism
222853_at	-1.227	5.561	-2.808	1.310e-02	0.185	-2.969	FLRT3	fibronectin leucine rich transmembrane protein 3	20	-14252642, -14252642	N71923	23767	20p11	Hs.41296	9	receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging
212805_at	2.209	6.490	2.808	1.310e-02	0.185	-2.969	PRUNE2	prune homolog 2 (Drosophila)	9	-78416111	AB002365	158471	9q21.2	Hs.262857	14	cytoplasm apoptosis induction of apoptosis oxidoreductase activity manganese ion binding metal ion binding transition metal ion binding G1 phase
207977_s_at	0.647	7.245	2.808	1.311e-02	0.185	-2.969	DPT	dermatopontin	1	-166931329	NM_001937	1805	1q12-q23	Hs.80552	13	protein binding extracellular region proteinaceous extracellular matrix cell adhesion negative regulation of cell proliferation collagen fibril organization
1558705_at	0.317	5.991	2.808	1.312e-02	0.185	-2.970	ATOH8	atonal homolog 8 (Drosophila)	2	85834419	AL831857	84913	2p11.2	Hs.135569 Hs.436464	5	DNA binding nucleus multicellular organismal development nervous system development cell differentiation transcription regulator activity regulation of transcription
238066_at	0.721	5.873	2.807	1.314e-02	0.185	-2.972	RBP7	retinol binding protein 7, cellular	1	9979841	AI733027	116362	1p36.22	Hs.422688	4	transporter activity cytoplasm transport lipid binding retinal binding retinol binding
204431_at	-0.279	6.607	-2.806	1.316e-02	0.186	-2.973	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	19	-2948636, -2948636, -2948636	NM_003260	7089	19p13.3	Hs.332173	15	protein binding nucleus signal transduction organ morphogenesis Wnt receptor signaling pathway regulation of transcription
225730_s_at	0.368	7.536	2.805	1.317e-02	0.186	-2.974	THUMPD3	THUMP domain containing 3	3	9379716	AI921788	25917	3p25.3	Hs.443081	5	RNA binding protein binding methyltransferase activity transferase activity
214873_at	0.254	3.851	2.805	1.318e-02	0.186	-2.974	LRP5L	low density lipoprotein receptor-related protein 5-like	22	-24077385, -24077385	AL137651	91355	22q11.23	Hs.634058	3	membrane
235312_s_at	-1.165	6.808	-2.805	1.318e-02	0.186	-2.974	NRAP	nebulin-related anchoring protein	10	-115338572	AA195854	4892	10q24-q26	Hs.268788	14	actin binding actin binding protein binding fascia adherens muscle tendon junction biological_process zinc ion binding metal ion binding muscle alpha-actinin binding
204370_at	-0.305	6.557	-2.805	1.319e-02	0.186	-2.975	CLP1	CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)	11	57181791	NM_006831	10978	11q12	Hs.523687	9	nucleotide binding tRNA-intron endonuclease complex magnesium ion binding nuclear mRNA splicing, via spliceosome ATP binding ATP binding GTP binding nucleus tRNA splicing, via endonucleolytic cleavage and ligation nickel ion binding kinase activity transferase activity manganese ion binding RNA interference, targeting of mRNA for destruction mRNA 3'-end processing RNA interference, siRNA loading onto RISC ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity
226277_at	-0.366	7.980	-2.805	1.319e-02	0.186	-2.975	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	5	-74702683, -74702683	AA889952	10087	5q13.3	Hs.270437	26	protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response
218488_at	0.195	9.280	2.805	1.319e-02	0.186	-2.975	EIF2B3	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	1	-45089036	NM_020365	8891	1p34.1	Hs.533549	25	translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm eukaryotic translation initiation factor 2B complex translational initiation biosynthetic process response to heat response to heat response to glucose stimulus oligodendrocyte development transferase activity nucleotidyltransferase activity negative regulation of translational initiation in response to stress response to peptide hormone stimulus cellular response to stimulus
213131_at	-0.673	6.098	-2.805	1.319e-02	0.186	-2.976	OLFM1	olfactomedin 1	9	137106909, 137106923	R38389	10439	9q34.3	Hs.522484	9	protein binding endoplasmic reticulum endoplasmic reticulum lumen multicellular organismal development nervous system development membrane
1558168_at	0.205	4.033	2.804	1.320e-02	0.186	-2.976	C3orf47	chromosome 3 open reading frame 47	3	130517803	AL040547	339942	3q21.3	Hs.450096 Hs.75307	5
201454_s_at	-0.436	9.084	-2.804	1.320e-02	0.186	-2.976	NPEPPS	aminopeptidase puromycin sensitive	17	42963442	AW055008	9520	17q21	Hs.443837	14	aminopeptidase activity protein binding nucleus cytoplasm cytosol proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding
223993_s_at	0.338	9.370	2.804	1.321e-02	0.186	-2.976	CNIH4	cornichon homolog 4 (Drosophila)	1	222611217	AL136930	29097	1q42.11	Hs.195403 Hs.445890	11	protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane
225682_s_at	0.200	6.785	2.804	1.322e-02	0.186	-2.977	POLR3H	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	22	-40251752, -40251751	AI587069	171568	22q13.2	Hs.712617	10	DNA-directed RNA polymerase activity nucleus nucleoplasm DNA-directed RNA polymerase III complex transcription transcription from RNA polymerase III promoter	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
226939_at	-0.591	6.972	-2.804	1.322e-02	0.186	-2.977	CPEB2	cytoplasmic polyadenylation element binding protein 2	4	14614619	AI202327	132864	4p15.33	Hs.656937	4	nucleotide binding RNA binding cytoplasm regulation of translation
228058_at	0.221	4.060	2.804	1.323e-02	0.186	-2.978	ZG16B	zymogen granule protein 16 homolog B (rat)	16	2820173	AI559190	124220	16p13.3	Hs.105887	10	sugar binding extracellular region
1558251_a_at	0.274	3.079	2.803	1.323e-02	0.186	-2.978	ZNF587	zinc finger protein 587	19	63053080	AK055448	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210344_at	0.231	5.993	2.803	1.324e-02	0.186	-2.979	OSBPL7	oxysterol binding protein-like 7	17	-43239731	AF323729	114881	17q21	Hs.463320	6	lipid transport steroid metabolic process
220273_at	0.251	3.885	2.803	1.324e-02	0.186	-2.979	IL17B	interleukin 17B	5	-148734022	NM_014443	27190	5q32-q34	Hs.156979	9	signal transducer activity cytokine activity extracellular region extracellular space inflammatory response immune response cell-cell signaling	Cytokine-cytokine receptor interaction
233197_at	0.383	4.984	2.802	1.326e-02	0.186	-2.980	KLHL9	kelch-like 9 (Drosophila)	9	-21321017	AK022805	55958	9p22	Hs.522029 Hs.701778 Hs.710126	4	protein binding modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
226961_at	0.303	3.995	2.802	1.326e-02	0.186	-2.980	PRR15	proline rich 15	7	29569951	AI347918	222171	7p14.3	Hs.91109	3	multicellular organismal development
221870_at	0.357	7.153	2.802	1.326e-02	0.186	-2.980	EHD2	EH-domain containing 2	19	52908412	AI417917	30846	19q13.3	Hs.719225	10	nucleotide binding nucleic acid binding GTPase activity calcium ion binding ATP binding GTP binding membrane fraction nucleus endosome plasma membrane endocytosis hydrolase activity protein domain specific binding cortical actin cytoskeleton organization	Endocytosis
221925_s_at	-0.387	5.022	-2.802	1.326e-02	0.186	-2.980	CSPP1	centrosome and spindle pole associated protein 1	8	68139156	BE044503	79848	8q13.1-q13.2	Hs.370147	6	centrosome microtubule
222838_at	0.425	2.920	2.802	1.327e-02	0.186	-2.981	SLAMF7	SLAM family member 7	1	158975700	AL121985	57823	1q23.1-q24.1	Hs.517265	21	receptor activity cell adhesion membrane integral to membrane natural killer cell activation natural killer cell mediated cytotoxicity
225803_at	-0.962	10.166	-2.802	1.328e-02	0.186	-2.981	FBXO32	F-box protein 32	8	-124584538, -124584538	AW006123	114907	8q24.13	Hs.403933	17	protein binding modification-dependent protein catabolic process
244317_at	0.454	4.230	2.802	1.328e-02	0.186	-2.981	KIAA1324L	KIAA1324-like	7	-86347173, -86347173	BF035563	222223	7q21.12	Hs.208093	3	G-protein coupled receptor activity protein binding G-protein coupled receptor protein signaling pathway membrane integral to membrane
210075_at	0.428	7.352	2.801	1.328e-02	0.186	-2.982	MARCH2	membrane-associated ring finger (C3HC4) 2	19	8384186	AF151074	51257	19p13.2	Hs.631861	10	lysosome endosome endoplasmic reticulum endocytosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
201520_s_at	-0.462	9.375	-2.801	1.328e-02	0.186	-2.982	GRSF1	G-rich RNA sequence binding factor 1	4	-71900362, -71900362	BF034561	2926	4q13	Hs.309763	6	mRNA binding cytoplasm mRNA polyadenylation
219515_at	-0.645	6.229	-2.801	1.329e-02	0.186	-2.982	PRDM10	PR domain containing 10	11	-129274810, -129274810	NM_020228	56980	11q25	Hs.275086	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
244431_at	0.324	4.779	2.801	1.329e-02	0.186	-2.982	KILLIN	killin protein	10	-89608897	AA057423	100144748	10q23	Hs.559820	2	DNA binding nucleus apoptosis cell cycle
232346_at	0.318	4.903	2.800	1.331e-02	0.186	-2.984	LOC388692	hypothetical LOC388692	1	147546099	AW515373	388692	1q21.2	Hs.271249 Hs.454790 Hs.719421	2
213371_at	-0.322	12.651	-2.800	1.332e-02	0.186	-2.984	LDB3	LIM domain binding 3	10	88418300, 88418405, 88418405	AI803302	11155	10q22.3-q23.2	Hs.657271	15	protein binding cytoplasm cytoskeleton zinc ion binding Z disc pseudopodium metal ion binding perinuclear region of cytoplasm
235836_at	-0.407	4.401	-2.800	1.333e-02	0.186	-2.985	MXRA7	matrix-remodelling associated 7	17	-72187245, -72183403	N51413	439921	17q25.1	Hs.250723 Hs.597019 Hs.707692	4	membrane integral to membrane
222725_s_at	-0.529	7.474	-2.799	1.334e-02	0.186	-2.985	PALMD	palmdelphin	1	99884018	AI082747	54873	1p22-p21	Hs.483993	7	cytoplasm regulation of cell shape membrane
235153_at	-0.276	4.633	-2.799	1.335e-02	0.186	-2.986	RNF183	ring finger protein 183	9	-115099193	BE796148	138065	9q32	Hs.211374	4	protein binding zinc ion binding membrane integral to membrane metal ion binding
213940_s_at	0.276	6.598	2.799	1.335e-02	0.186	-2.986	FNBP1	formin binding protein 1	9	-131689286	AU145053	23048	9q34	Hs.189409	25	cytoplasm lysosome cytoskeleton plasma membrane cell cortex endocytosis lipid binding cytoplasmic vesicle identical protein binding
206271_at	0.258	3.162	2.799	1.335e-02	0.186	-2.986	TLR3	toll-like receptor 3	4	187227302	NM_003265	7098	4q35	Hs.657724	158	double-stranded RNA binding double-stranded RNA binding transmembrane receptor activity protein binding endosome endoplasmic reticulum integral to plasma membrane inflammatory response hyperosmotic response signal transduction activation of NF-kappaB-inducing kinase activity detection of virus endosome membrane endosome membrane membrane positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production defense response to bacterium positive regulation of I-kappaB kinase/NF-kappaB cascade response to exogenous dsRNA positive regulation of interferon-gamma biosynthetic process positive regulation of chemokine biosynthetic process innate immune response positive regulation of interferon-alpha biosynthetic process positive regulation of interferon-beta biosynthetic process positive regulation of interferon-beta biosynthetic process negative regulation of osteoclast differentiation positive regulation of JNK cascade positive regulation of NF-kappaB transcription factor activity	Toll-like receptor signaling pathway
222642_s_at	-0.420	5.374	-2.799	1.336e-02	0.186	-2.987	TMEM33	transmembrane protein 33	4	41631893	BC000948	55161	4p13	Hs.31082	5	protein binding biological_process membrane integral to membrane melanosome
213418_at	0.386	5.019	2.799	1.336e-02	0.186	-2.987	HSPA6	heat shock 70kDa protein 6 (HSP70B')	1	159760659	NM_002155	3310	1q23	Hs.654614	24	nucleotide binding ATP binding response to unfolded protein	MAPK signaling pathway Endocytosis Antigen processing and presentation
1564537_a_at	0.348	6.672	2.798	1.336e-02	0.186	-2.987	ASB10	ankyrin repeat and SOCS box-containing 10	7	-150503717, -150503717	AK055536	136371	7q36.1	Hs.647081	6	intracellular signaling cascade modification-dependent protein catabolic process
212409_s_at	-0.577	5.992	-2.798	1.336e-02	0.186	-2.987	TOR1AIP1	torsin A interacting protein 1	1	178118042	AK021613	26092	1q24.2	Hs.496459	9	nucleus membrane integral to membrane
219981_x_at	0.263	7.115	2.798	1.337e-02	0.186	-2.987	ZNF587	zinc finger protein 587	19	63053080	NM_017961	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224796_at	0.319	6.708	2.798	1.337e-02	0.186	-2.987	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	8	-131133534	W03103	50807	8q24.1-q24.2	Hs.655552	19	protein binding cytoplasm ARF GTPase activator activity zinc ion binding membrane regulation of ARF GTPase activity metal ion binding	Endocytosis Fc gamma R-mediated phagocytosis
222623_s_at	-0.459	7.764	-2.798	1.337e-02	0.186	-2.988	ZNF639	zinc finger protein 639	3	180524244	BF001614	51193	3q26.33	Hs.632578	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
208148_at	-0.366	5.119	-2.797	1.339e-02	0.186	-2.989	MYH4	myosin, heavy chain 4, skeletal muscle	17	-10287332	NM_017533	4622	17p13.1	Hs.711141	9	microfilament motor activity nucleotide binding actin binding calmodulin binding ATP binding cytoplasm striated muscle thick filament striated muscle contraction structural constituent of muscle response to activity myosin complex actin filament-based movement muscle filament sliding	Tight junction
232662_x_at	0.338	7.435	2.797	1.340e-02	0.187	-2.990	C10orf58	chromosome 10 open reading frame 58	10	82158221, 82163570	AK022598	84293	10q23.1	Hs.500333 Hs.718589	10	extracellular region
230015_at	0.252	4.649	2.797	1.340e-02	0.187	-2.990	PRCD	progressive rod-cone degeneration	17	72047715	AV729651	768206	17q25.1	Hs.634380	3	cytoplasm visual perception membrane integral to membrane response to stimulus
226951_at	-0.581	6.202	-2.797	1.341e-02	0.187	-2.990	C2orf49	chromosome 2 open reading frame 49	2	105320444	AI741415	79074	2q12.1	Hs.549577	4	molecular_function cellular_component biological_process
1564679_at	-0.750	6.700	-2.796	1.342e-02	0.187	-2.991	ASB15	ankyrin repeat and SOCS box-containing 15	7	123036347	AF403033	142685	7q31.31	Hs.83916	6	intracellular signaling cascade modification-dependent protein catabolic process
216468_s_at	0.468	2.068	2.796	1.344e-02	0.187	-2.992	ZNF682	zinc finger protein 682	19	-19976226, -19976226	AC006539	91120	19p12	Hs.306298	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209034_at	-0.421	10.368	-2.794	1.347e-02	0.187	-2.994	PNRC1	proline-rich nuclear receptor coactivator 1	6	89847147	AF279899	10957	6q15	Hs.703798 Hs.75969	11	protein binding nucleus regulation of transcription
200697_at	-0.325	9.866	-2.794	1.347e-02	0.187	-2.995	HK1	hexokinase 1	10	70699761, 70745615, 70748608	NM_000188	3098	10q22	Hs.370365	40	nucleotide binding hexokinase activity hexokinase activity ATP binding mitochondrion mitochondrial outer membrane cytosol cytosol carbohydrate metabolic process glycolysis membrane kinase activity transferase activity	Glycolysis / Gluconeogenesis Fructose and mannose metabolism Galactose metabolism Starch and sucrose metabolism Amino sugar and nucleotide sugar metabolism Streptomycin biosynthesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Insulin signaling pathway Type II diabetes mellitus
214883_at	-0.218	5.062	-2.794	1.348e-02	0.187	-2.995	THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	17	35472588, 35472685	X55005	7067	17q11.2	Hs.724	95	transcription factor activity steroid hormone receptor activity thyroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter zinc ion binding hormone-mediated signaling regulation of specific transcription from RNA polymerase II promoter promoter binding metal ion binding	Neuroactive ligand-receptor interaction
200030_s_at	0.232	12.848	2.794	1.348e-02	0.187	-2.995	SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	12	97511533	NM_002635	5250	12q23	Hs.290404	16	binding mitochondrion mitochondrial inner membrane integral to plasma membrane generation of precursor metabolites and energy transport symporter activity phosphate carrier activity membrane
208205_at	0.261	4.128	2.794	1.349e-02	0.187	-2.996	PCDHA9	protocadherin alpha 9	5	140207540, 140207540	NM_014005	9752	5q31	Hs.199343	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
222515_x_at	0.298	5.025	2.793	1.350e-02	0.187	-2.996	TMEM165	transmembrane protein 165	4	55956846	AI671397	55858	4q12	Hs.479766	6	membrane integral to membrane
228357_at	-0.419	5.296	-2.792	1.353e-02	0.187	-2.998	UNK	unkempt homolog (Drosophila)	17	71292275	BE966979	85451	17q25.1	Hs.584768	5	nucleic acid binding protein binding zinc ion binding metal ion binding
1569291_at	-0.201	6.063	-2.792	1.353e-02	0.187	-2.999	CROCCL1	ciliary rootlet coiled-coil, rootletin-like 1	1	-16817339	BC015342	84809	1p36.13	Hs.631865	2
210300_at	0.232	6.099	2.792	1.355e-02	0.188	-3.000	REM1	RAS (RAD and GEM)-like GTP-binding 1	20	29526765	AF152863	28954	20q11.21	Hs.247729	8	nucleotide binding calmodulin binding GTP binding small GTPase mediated signal transduction
201788_at	-0.303	8.244	-2.791	1.356e-02	0.188	-3.000	DDX42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42	17	59205298	NM_007372	11325	17q23.3	Hs.702010	10	nucleotide binding RNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity Cajal body nuclear speck hydrolase activity
241809_at	0.436	5.959	2.791	1.356e-02	0.188	-3.001	C1orf183	chromosome 1 open reading frame 183	1	-112069892, -112069892	BE906233	55924	1p13.2	Hs.193406 Hs.657857	3
218027_at	0.302	10.581	2.791	1.357e-02	0.188	-3.001	MRPL15	mitochondrial ribosomal protein L15	8	55210333	NM_014175	29088	8q11.2-q13	Hs.18349	12	structural constituent of ribosome intracellular mitochondrion ribosome translation large ribosomal subunit
34858_at	-0.325	6.911	-2.790	1.358e-02	0.188	-3.002	KCTD2	potassium channel tetramerisation domain containing 2	17	70554873	D79998	23510	17q25.1	Hs.514468	5	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
203683_s_at	0.387	6.853	2.790	1.359e-02	0.188	-3.002	VEGFB	vascular endothelial growth factor B	11	63758841	NM_003377	7423	11q13	Hs.78781	23	regulation of cell growth vascular endothelial growth factor receptor binding protein binding extracellular region extracellular region signal transduction growth factor activity heparin binding positive regulation of cell proliferation membrane platelet alpha granule lumen	Cytokine-cytokine receptor interaction mTOR signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer
219645_at	-0.301	12.238	-2.790	1.360e-02	0.188	-3.003	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	1	158426908	NM_001231	844	1q21	Hs.632476	12	calcium ion binding mitochondrion mitochondrial matrix smooth endoplasmic reticulum sarcoplasmic reticulum lumen
238140_at	0.369	3.468	2.790	1.360e-02	0.188	-3.003	ARV1	ARV1 homolog (S. cerevisiae)	1	229181445	AI346356	64801	1q42.2	Hs.275736	6	lipid metabolic process sphingolipid metabolic process membrane integral to membrane
210401_at	0.571	6.348	2.790	1.361e-02	0.188	-3.004	P2RX1	purinergic receptor P2X, ligand-gated ion channel, 1	17	-3746633	U45448	5023	17p13.3	Hs.41735	42	purinergic nucleotide receptor activity serotonin secretion by platelet regulation of vascular smooth muscle contraction receptor activity ATP-gated cation channel activity calcium channel activity protein binding ATP binding plasma membrane plasma membrane integral to plasma membrane activation of caspase activity signal transduction insemination regulation of blood pressure death synaptosome platelet activation external side of cell outer membrane response to ATP synaptic transmission, glutamatergic vasoconstriction protein homodimerization activity positive regulation of ion transport membrane raft postsynaptic membrane ceramide biosynthetic process protein heterodimerization activity response to stimulus regulation of calcium ion transport	Calcium signaling pathway Neuroactive ligand-receptor interaction
221601_s_at	1.021	4.906	2.789	1.361e-02	0.188	-3.004	FAIM3	Fas apoptotic inhibitory molecule 3	1	-205143252, -205143252	AI084226	9214	1q32.1	Hs.58831 Hs.719320	10	nucleus cytoplasm plasma membrane focal adhesion anti-apoptosis immune response cellular defense response integral to membrane
AFFX-HUMGAPDH/M33197_M_at	-0.225	13.668	-2.788	1.365e-02	0.188	-3.006	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	AFFX-HUMGAPDH/M33197_M	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
1555229_a_at	0.388	3.109	2.788	1.365e-02	0.188	-3.006	C1S	complement component 1, s subcomponent	12	7038240	BC007010	716	12p13	Hs.458355	42	serine-type endopeptidase activity calcium ion binding extracellular region proteolysis complement activation, classical pathway peptidase activity innate immune response	Complement and coagulation cascades Systemic lupus erythematosus
238853_at	0.467	5.489	2.788	1.365e-02	0.188	-3.006	RAB3IP	RAB3A interacting protein (rabin3)	12	68418897, 68419446, 68459020	AI436813	117177	12q14.3	Hs.258209	11	guanyl-nucleotide exchange factor activity protein binding protein binding nucleus cytoplasm cytosol protein transport
200959_at	0.317	8.375	2.788	1.366e-02	0.188	-3.007	FUS	fusion (involved in t(12;16) in malignant liposarcoma)	16	31098953	NM_004960	2521	16p11.2	Hs.513522	55	nuclear mRNA splicing, via spliceosome DNA binding RNA binding protein binding intracellular nucleus nucleolus cell death zinc ion binding metal ion binding
239482_x_at	0.288	5.646	2.788	1.366e-02	0.188	-3.007	ZNF708	zinc finger protein 708	19	-21265802	BF223715	7562	19p12	Hs.466296	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222640_at	-0.374	6.993	-2.787	1.366e-02	0.188	-3.007	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	2	-25357824, -25309348, -25309348, -25309348	N26002	1788	2p23	Hs.515840	54	euchromatin DNA binding DNA (cytosine-5-)-methyltransferase activity protein binding nucleus cytoplasm DNA methylation genetic imprinting methyltransferase activity zinc ion binding nuclear matrix transferase activity metal ion binding	Cysteine and methionine metabolism Metabolic pathways
229578_at	-0.448	9.090	-2.787	1.367e-02	0.188	-3.008	JPH2	junctophilin 2	20	-42238870, -42173750	AA716165	57158	20q13.12	Hs.441737	11	protein binding membrane fraction microsome plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
236253_at	0.253	4.419	2.787	1.367e-02	0.188	-3.008	ZNF546	zinc finger protein 546	19	45194782	BE548749	339327	19q13.2	Hs.709400	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201262_s_at	0.238	4.882	2.787	1.367e-02	0.188	-3.008	BGN	biglycan	X	152413604	NM_001711	633	Xq28	Hs.821	63	extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix biological_process transport vesicle
217628_at	-0.727	6.155	-2.787	1.367e-02	0.188	-3.008	CLIC5	chloride intracellular channel 5	6	-45974165, -45974165	BF032808	53405	6p21.1-p12.1	Hs.485489	15	voltage-gated ion channel activity voltage-gated chloride channel activity protein binding insoluble fraction cytoplasm Golgi apparatus centrosome cell cortex ion transport chloride transport female pregnancy actin cytoskeleton membrane integral to membrane chloride ion binding chloride channel complex
200967_at	0.519	7.624	2.787	1.368e-02	0.188	-3.008	PPIB	peptidylprolyl isomerase B (cyclophilin B)	15	-62235066	NM_000942	5479	15q21-q22	Hs.434937	41	peptidyl-prolyl cis-trans isomerase activity endoplasmic reticulum endoplasmic reticulum lumen protein folding isomerase activity peptide binding melanosome unfolded protein binding
229468_at	0.298	5.973	2.786	1.370e-02	0.188	-3.009	CDK3	cyclin-dependent kinase 3	17	71508581	AI885421	1018	17q22-qter	Hs.706766	21	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation cell cycle mitosis cell proliferation transferase activity cell division
227058_at	0.275	6.071	2.786	1.371e-02	0.189	-3.011	C13orf33	chromosome 13 open reading frame 33	13	30378311	AW084730	84935	13q12.3	Hs.646647 Hs.708377	4
206082_at	0.489	5.129	2.786	1.372e-02	0.189	-3.011	HCP5	HLA complex P5	6	31538935, 2877117	NM_006674	10866	6p21.3	Hs.654480	12	defense response
225087_at	-0.516	8.708	-2.785	1.373e-02	0.189	-3.012	C16orf63	chromosome 16 open reading frame 63	16	-15867077	AA524072	123811	16p13.11	Hs.514179	3
231808_at	-0.354	6.965	-2.785	1.373e-02	0.189	-3.012	LOC729082	hypothetical protein LOC729082	15	39363492	AY007106	729082	15q15.1	Hs.380164	2
213762_x_at	-0.372	8.528	-2.785	1.373e-02	0.189	-3.012	RBMX	RNA binding motif protein, X-linked	X	-135783284	AI452524	27316	Xq26.3	Hs.380118 Hs.710162	32	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex biological_process RNA splicing heterogeneous nuclear ribonucleoprotein complex
241405_at	-0.417	5.644	-2.785	1.374e-02	0.189	-3.012	LOC400604	hypothetical gene supported by BC039664	17		AI085535	400604	17q21.33	Hs.641441	1
220664_at	0.216	3.974	2.785	1.374e-02	0.189	-3.012	SPRR2C	small proline-rich protein 2C (pseudogene)	1	-151379217	NM_006518	6702	1q21-q22	Hs.2421	5
223749_at	0.413	4.696	2.785	1.374e-02	0.189	-3.013	C1QTNF2	C1q and tumor necrosis factor related protein 2	5	-159707352	AF329836	114898	5q33.3	Hs.110062	3	activation of MAPK activity receptor binding extracellular region extracellular space positive regulation of glycogen biosynthetic process positive regulation of fatty acid oxidation positive regulation of glucose import protein homooligomerization
227946_at	-0.538	6.896	-2.785	1.374e-02	0.189	-3.013	OSBPL7	oxysterol binding protein-like 7	17	-43239731	AI955239	114881	17q21	Hs.463320	6	lipid transport steroid metabolic process
215313_x_at	0.659	10.617	2.784	1.375e-02	0.189	-3.013	HLA-A	major histocompatibility complex, class I, A	6	30018309, 1358588, 1157055	AA573862	3105	6p21.3	Hs.181244 Hs.713441	857	Golgi membrane antigen processing and presentation of peptide antigen via MHC class I protein binding integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation early endosome membrane MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
225158_at	-0.461	8.088	-2.784	1.375e-02	0.189	-3.013	GFM1	G elongation factor, mitochondrial 1	3	159845010	BF978647	85476	3q25.1-q26.2	Hs.518355	11	nucleotide binding translation elongation factor activity GTPase activity GTP binding intracellular mitochondrion translational elongation
212432_at	0.321	8.426	2.784	1.375e-02	0.189	-3.013	GRPEL1	GrpE-like 1, mitochondrial (E. coli)	4	-7112680	AL542571	80273	4p16	Hs.443723	6	adenyl-nucleotide exchange factor activity mitochondrion mitochondrial matrix protein folding protein import into mitochondrial matrix protein homodimerization activity unfolded protein binding chaperone binding
241926_s_at	0.468	4.334	2.784	1.375e-02	0.189	-3.013	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	21	-38673821, -38673821	AA296657	2078	21q22.3	Hs.473819	66	transcription factor activity signal transducer activity protein binding nucleus regulation of transcription, DNA-dependent protein amino acid phosphorylation signal transduction multicellular organismal development cell proliferation sequence-specific DNA binding
231767_at	0.260	6.338	2.784	1.377e-02	0.189	-3.014	HOXB4	homeobox B4	17	-44007867	AL137449	3214	17q21-q22	Hs.664706	28	negative regulation of transcription from RNA polymerase II promoter morphogenesis of an epithelial sheet transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development cell proliferation anterior/posterior pattern formation transcription repressor activity sequence-specific DNA binding somatic stem cell division spleen development bone marrow development embryonic skeletal system morphogenesis definitive hemopoiesis
203232_s_at	-0.513	7.933	-2.783	1.377e-02	0.189	-3.015	ATXN1	ataxin 1	6	-16407321	NM_000332	6310	6p23	Hs.434961 Hs.712106	65	RNA binding nucleus nucleoplasm nucleolus cytoplasm RNA processing protein C-terminus binding cell death poly(U) RNA binding adult locomotory behavior visual learning nuclear matrix negative regulation of transcription transcription repressor activity poly(G) RNA binding nuclear RNA export factor complex negative regulation of phosphorylation nuclear inclusion body identical protein binding negative regulation of insulin-like growth factor receptor signaling pathway protein self-association positive regulation of transcription from RNA polymerase II promoter nuclear export regulation of excitatory postsynaptic membrane potential
232154_at	0.278	4.985	2.783	1.378e-02	0.189	-3.015	LOC199800	hypothetical protein LOC199800	19	54883753	AL359598	199800	19q13.33	Hs.311193 Hs.607562	1
48531_at	-0.392	7.471	-2.783	1.378e-02	0.189	-3.015	TNIP2	TNFAIP3 interacting protein 2	4	-2713184, -2713184	AA522816	79155	4p16.3	Hs.719161	20	protein binding cytoplasm I-kappaB kinase/NF-kappaB cascade
1556736_at	0.225	4.380	2.783	1.380e-02	0.189	-3.016	LOC100129858	hypothetical protein LOC100129858	4		AK095554	100129858	4q31.1	Hs.660477	1
204725_s_at	-0.381	7.380	-2.782	1.380e-02	0.189	-3.017	NCK1	NCK adaptor protein 1	3	138063762	NM_006153	4690	3q21	Hs.477693	110	receptor binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal complex assembly cytoskeletal adaptor activity vesicle membrane cell migration protein domain specific binding lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
201152_s_at	-0.490	10.284	-2.782	1.382e-02	0.189	-3.017	MBNL1	muscleblind-like (Drosophila)	3	153468518, 153499883	N31913	4154	3q25	Hs.478000 Hs.558914	21	in utero embryonic development double-stranded RNA binding nucleus cytoplasm nervous system development muscle organ development zinc ion binding embryonic limb morphogenesis myoblast differentiation metal ion binding
207700_s_at	-0.700	7.525	-2.782	1.382e-02	0.189	-3.018	NCOA3	nuclear receptor coactivator 3	20	45564063	NM_006534	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
242608_x_at	-0.297	8.275	-2.781	1.384e-02	0.189	-3.019	FAM161B	family with sequence similarity 161, member B	14	-73470457	AW517479	145483	14q24.3	Hs.660789	4
213982_s_at	0.585	4.676	2.781	1.385e-02	0.189	-3.019	RABGAP1L	RAB GTPase activating protein 1-like	1	172395256, 173111306	BG107203	9910	1q24	Hs.585378	9	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
240456_at	0.319	4.199	2.781	1.385e-02	0.189	-3.019	ANKRD55	ankyrin repeat domain 55	5	-55431263, -55431263	AA459699	79722	5q11.2	Hs.436214	5
207318_s_at	-0.285	7.100	-2.781	1.385e-02	0.189	-3.020	CDC2L5	cell division cycle 2-like 5 (cholinesterase-related cell division controller)	7	39956483	AJ297710	8621	7p13	Hs.233552	18	nucleotide binding cyclin-dependent protein kinase activity ATP binding protein amino acid phosphorylation regulation of mitosis multicellular organismal development positive regulation of cell proliferation transferase activity
209438_at	0.428	5.146	2.781	1.385e-02	0.189	-3.020	PHKA2	phosphorylase kinase, alpha 2 (liver)	X	-18820336	AL096700	5256	Xp22.2-p22.1	Hs.54941 Hs.607628 Hs.622882	29	catalytic activity phosphorylase kinase activity calmodulin binding plasma membrane phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy protein modification process	Calcium signaling pathway Insulin signaling pathway
65133_i_at	0.517	4.339	2.781	1.386e-02	0.189	-3.020	INO80B	INO80 complex subunit B	2	74535706	AI862454	83444	2p13.1	Hs.410786	7	nucleus nucleolus zinc ion binding metal ion binding
213578_at	-0.328	6.972	-2.780	1.386e-02	0.189	-3.020	BMPR1A	bone morphogenetic protein receptor, type IA	10	88506375	AI678679	657	10q22.3	Hs.524477	70	nucleotide binding magnesium ion binding mesoderm formation Mullerian duct regression positive regulation of mesenchymal cell proliferation protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity ATP binding plasma membrane plasma membrane caveola protein amino acid phosphorylation immune response transforming growth factor beta receptor signaling pathway pattern specification process ectoderm development heart development dorsal/ventral axis specification anterior/posterior pattern formation positive regulation of pathway-restricted SMAD protein phosphorylation integral to membrane transferase activity stem cell maintenance manganese ion binding cell differentiation lung development positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway hindlimb morphogenesis odontogenesis of dentine-containing tooth protein homodimerization activity positive regulation of osteoblast differentiation SMAD binding mesendoderm development embryonic morphogenesis positive regulation of epithelial cell proliferation negative regulation of neurogenesis cartilage development palate development positive regulation of SMAD protein nuclear translocation	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
207188_at	0.272	5.404	2.780	1.386e-02	0.189	-3.021	CDK3	cyclin-dependent kinase 3	17	71508581	NM_001258	1018	17q22-qter	Hs.706766	21	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation cell cycle mitosis cell proliferation transferase activity cell division
223072_s_at	0.252	7.061	2.780	1.386e-02	0.189	-3.021	WBP1	WW domain binding protein 1	2	74539084	U79457	23559	2p12	Hs.516114	9	protein binding protein binding biological_process integral to membrane WW domain binding WW domain binding
1557633_at	-0.297	4.525	-2.780	1.387e-02	0.189	-3.021	POM121L8P	POM121 membrane glycoprotein-like 8 (rat) pseudogene	22	19966713	BC035394	29797	22q11.2	Hs.318898 Hs.645245 Hs.648261 Hs.648270	4
227420_at	0.326	5.645	2.780	1.387e-02	0.189	-3.021	TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	19	4590529	BF338045	126282	19p13.3	Hs.465643	3
204879_at	-0.338	5.889	-2.779	1.389e-02	0.189	-3.022	PDPN	podoplanin	1	13782838, 13784553	NM_006474	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
1557545_s_at	0.414	2.649	2.779	1.390e-02	0.189	-3.023	RNF165	ring finger protein 165	18	42168184	BF529886	494470	18q21.1	Hs.501114	4	protein binding zinc ion binding metal ion binding
207067_s_at	0.215	4.696	2.779	1.390e-02	0.189	-3.023	HDC	histidine decarboxylase	15	-48321437	NM_002112	3067	15q21-q22	Hs.1481	37	histidine decarboxylase activity cellular amino acid and derivative metabolic process histidine metabolic process lyase activity carboxylic acid metabolic process pyridoxal phosphate binding catecholamine biosynthetic process	Histidine metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
205292_s_at	-0.297	10.479	-2.779	1.391e-02	0.189	-3.024	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	7	-26196080	NM_002137	3181	7p15	Hs.487774	54	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm RNA splicing heterogeneous nuclear ribonucleoprotein complex single-stranded telomeric DNA binding RNA transport
209929_s_at	0.305	6.944	2.778	1.393e-02	0.189	-3.025	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	X	153423652, 153428755, 153428755, 153429255	AF091453	8517	Xq28	Hs.43505	122	signal transducer activity protein binding nucleus cytosol induction of apoptosis immune response I-kappaB kinase/NF-kappaB cascade zinc ion binding IkappaB kinase complex interspecies interaction between organisms regulation of transcription metal ion binding T cell receptor signaling pathway T cell receptor signaling pathway	MAPK signaling pathway Chemokine signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Pancreatic cancer Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Primary immunodeficiency
203320_at	1.060	6.515	2.778	1.393e-02	0.189	-3.025	SH2B3	SH2B adaptor protein 3	12	110328134	NM_005475	10019	12q24	Hs.506784	22	signal transducer activity protein binding intracellular signaling cascade	Neurotrophin signaling pathway
221522_at	-0.530	6.708	-2.778	1.393e-02	0.189	-3.025	ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	19	-37779746	AL136784	84079	19q13.11	Hs.59236	12	guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm lysosome early endosome early endosome to late endosome transport
204392_at	0.267	4.782	2.778	1.393e-02	0.189	-3.025	CAMK1	calcium/calmodulin-dependent protein kinase I	3	-9774030	NM_003656	8536	3p25.3	Hs.434875	31	nucleotide binding calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm protein amino acid phosphorylation nucleocytoplasmic transport signal transduction multicellular organismal development nervous system development transferase activity cell differentiation
226797_at	-0.435	6.989	-2.778	1.394e-02	0.189	-3.025	MBTD1	mbt domain containing 1	17	-46609784	AL133577	54799	17q21.33	Hs.656803	2	nucleus zinc ion binding regulation of transcription metal ion binding
231798_at	0.614	5.036	2.777	1.395e-02	0.189	-3.026	NOG	noggin	17	52026058	AL575177	9241	17q21-q22	Hs.248201	48	osteoblast differentiation ureteric bud development epithelial to mesenchymal transition extracellular region extracellular region extracellular space pattern specification process brain development dorsal/ventral pattern formation cytokine binding negative regulation of BMP signaling pathway prostate gland development somatic stem cell maintenance wound healing middle ear morphogenesis embryonic digit morphogenesis protein homodimerization activity negative regulation of cell differentiation notochord morphogenesis anatomical structure formation involved in morphogenesis embryonic skeletal system development negative regulation of astrocyte differentiation mesenchymal cell differentiation positive regulation of epithelial cell proliferation cartilage development negative regulation of cardiac muscle cell proliferation limb development embryonic skeletal joint morphogenesis negative regulation of cytokine activity	TGF-beta signaling pathway
1570344_at	0.270	4.362	2.777	1.395e-02	0.189	-3.026	LRPPRC	leucine-rich PPR-motif containing	2	-43966866	BG772870	10128	2p21	Hs.368084	15	condensed nuclear chromosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus nuclear inner membrane nuclear outer membrane nucleoplasm cytoplasm mitochondrion cytoskeleton transport microtubule binding membrane mitochondrial nucleoid regulation of transcription mitochondrion transport along microtubule perinuclear region of cytoplasm beta-tubulin binding actin filament binding mRNA transport
202239_at	0.463	6.553	2.777	1.395e-02	0.189	-3.027	PARP4	poly (ADP-ribose) polymerase family, member 4	13	-23893068	NM_006437	143	13q11	Hs.718412	22	DNA binding NAD+ ADP-ribosyltransferase activity intracellular nucleus cytoplasm DNA repair protein modification process protein amino acid ADP-ribosylation transport inflammatory response response to DNA damage stimulus cell death transferase activity, transferring glycosyl groups enzyme binding ribonucleoprotein complex response to drug	Base excision repair
214475_x_at	-0.528	9.392	-2.777	1.397e-02	0.190	-3.027	CAPN3	calpain 3, (p94)	15	40427592, 40438989, 40481879, 40484268	AF127764	825	15q15.1-q21.1	Hs.143261	66	calcium-dependent cysteine-type endopeptidase activity signal transducer activity calcium ion binding intracellular cytoplasm proteolysis muscle organ development peptidase activity
218175_at	0.300	8.233	2.777	1.397e-02	0.190	-3.027	CCDC92	coiled-coil domain containing 92	12	-122986907	NM_025140	80212	12q24.31	Hs.114111	5
201567_s_at	-0.411	10.036	-2.777	1.397e-02	0.190	-3.028	GOLGA4	golgi autoantigen, golgin subfamily a, 4	3	37259741	NM_002078	2803	3p22-p21.3	Hs.344151	21	cytoplasm Golgi apparatus trans-Golgi network membrane vesicle-mediated transport
208620_at	-0.402	9.978	-2.776	1.398e-02	0.190	-3.028	PCBP1	poly(rC) binding protein 1	2	70168088	U24223	5093	2p13-p12	Hs.2853	42	nuclear mRNA splicing, via spliceosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm mRNA metabolic process ribonucleoprotein complex
231908_at	0.277	4.401	2.775	1.400e-02	0.190	-3.030	ZDHHC18	zinc finger, DHHC-type containing 18	1	27025787	AL034380	84243	1p36.11	Hs.523710	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
216081_at	0.421	4.533	2.775	1.401e-02	0.190	-3.030	LAMA4	laminin, alpha 4	6	-112681678, -112535826	AK027151	3910	6q21	Hs.654572	32	receptor binding extracellular matrix structural constituent extracellular region basal lamina laminin-1 complex regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
234702_x_at	-0.275	2.142	-2.775	1.401e-02	0.190	-3.030	CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	7	116907252	S64699	1080	7q31.2	Hs.489786 Hs.621460 Hs.661104	750	nucleotide binding ion channel activity ATP-binding and phosphorylation-dependent chloride channel activity channel-conductance-controlling ATPase activity protein binding ATP binding cholesterol biosynthetic process ion transport respiratory gaseous exchange membrane integral to membrane basolateral plasma membrane apical plasma membrane hydrolase activity ATPase activity PDZ domain binding cholesterol transport transepithelial chloride transport lung development cytoplasmic vesicle membrane chloride ion binding chloride channel complex vasodilation response to drug response to peptide hormone stimulus response to estrogen stimulus	ABC transporters Vibrio cholerae infection
202118_s_at	-0.432	4.715	-2.775	1.403e-02	0.190	-3.031	CPNE3	copine III	8	87595771	AA541758	8895	8q21.3	Hs.191219	10	protein serine/threonine kinase activity transporter activity calcium-dependent phospholipid binding cytoplasm cytosol lipid metabolic process vesicle-mediated transport
203323_at	0.539	7.788	2.774	1.403e-02	0.190	-3.031	CAV2	caveolin 2	7	115926679	BF197655	858	7q31.1	Hs.212332 Hs.603096	50	negative regulation of endothelial cell proliferation protein binding intracellular Golgi apparatus plasma membrane integral to plasma membrane caveola vesicle fusion mitochondrion organization endoplasmic reticulum organization transport vesicle protein homodimerization activity vesicle docking perinuclear region of cytoplasm skeletal muscle fiber development protein oligomerization	Focal adhesion
202273_at	0.312	6.809	2.774	1.403e-02	0.190	-3.031	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5	-149473594	NM_002609	5159	5q31-q32	Hs.509067	183	nucleotide binding in utero embryonic development kidney development tissue homeostasis receptor activity platelet activating factor receptor activity platelet-derived growth factor beta-receptor activity vascular endothelial growth factor receptor activity platelet-derived growth factor receptor binding ATP binding nitrogen compound metabolic process signal transduction positive regulation of cell proliferation membrane integral to membrane transferase activity positive regulation of cell migration protein amino acid autophosphorylation platelet-derived growth factor receptor signaling pathway platelet-derived growth factor binding skeletal system morphogenesis smooth muscle tissue development regulation of peptidyl-tyrosine phosphorylation cell chemotaxis	MAPK signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Glioma Prostate cancer Melanoma
217856_at	-0.504	5.399	-2.774	1.404e-02	0.190	-3.032	RBM8A	RNA binding motif protein 8A	1	144218994	AF182415	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
1557399_at	0.293	4.098	2.774	1.405e-02	0.190	-3.033	LOC284009	hypothetical protein LOC284009	17	-2257024	AI678065	284009	17p13.3	Hs.632244	2
218010_x_at	0.484	5.704	2.774	1.405e-02	0.190	-3.033	PPDPF	pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)	20	61622576	NM_024299	79144	20q13.33	Hs.79625	3	multicellular organismal development cell differentiation
217835_x_at	-0.433	11.038	-2.773	1.406e-02	0.190	-3.033	C20orf24	chromosome 20 open reading frame 24	20	34667580, 34667605	NM_018840	55969	20q11.23	Hs.584985	7	molecular_function protein binding cellular_component biological_process
217820_s_at	-0.515	8.103	-2.773	1.406e-02	0.190	-3.034	ENAH	enabled homolog (Drosophila)	1	-223741156	NM_018212	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
201050_at	0.310	5.904	2.773	1.408e-02	0.190	-3.034	PLD3	phospholipase D family, member 3	19	45546171	NM_012268	23646	19q13.2	Hs.257008	11	phospholipase D activity endoplasmic reticulum metabolic process membrane integral to membrane lipid catabolic process hydrolase activity NAPE-specific phospholipase D activity
226092_at	-0.444	8.160	-2.772	1.409e-02	0.190	-3.036	MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	14	66777773	BF115203	64398	14q23.3	Hs.652312	23	protein binding nucleus cytoplasm plasma membrane tight junction cell junction	Tight junction
221376_at	0.289	5.608	2.772	1.409e-02	0.190	-3.036	FGF17	fibroblast growth factor 17	8	21956373	NM_003867	8822	8p21	Hs.248192	17	extracellular region extracellular region extracellular space signal transduction cell-cell signaling nervous system development growth factor activity positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
206322_at	0.247	3.628	2.772	1.410e-02	0.190	-3.036	SYN3	synapsin III	22	-31238539, -31238539	NM_003490	8224	22q12.3	Hs.608750	18	nucleotide binding catalytic activity calcium ion binding protein binding ATP binding neurotransmitter secretion membrane cell junction synaptic vesicle membrane cytoplasmic vesicle synapse
202806_at	0.656	6.324	2.771	1.411e-02	0.190	-3.037	DBN1	drebrin 1	5	-176816219, -176816219	NM_004395	1627	5q35.3	Hs.130316	32	actin binding profilin binding intracellular cytoplasm actin filament organization multicellular organismal development nervous system development cell differentiation dendrite actomyosin regulation of neuronal synaptic plasticity regulation of dendrite development
226065_at	0.372	6.761	2.771	1.411e-02	0.190	-3.037	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	N98595	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
206295_at	-1.266	4.533	-2.771	1.412e-02	0.190	-3.037	IL18	interleukin 18 (interferon-gamma-inducing factor)	11	-111519185	NM_001562	3606	11q22.2-q22.3	Hs.83077	389	angiogenesis response to hypoxia signal transducer activity cytokine activity interleukin-1 receptor binding extracellular region extracellular space immune response cell-cell signaling response to cold regulation of cell adhesion sleep chemokine biosynthetic process T-helper 1 type immune response T-helper 2 type immune response interleukin-2 biosynthetic process interferon-gamma biosynthetic process positive regulation of activated T cell proliferation interleukin-13 biosynthetic process granulocyte macrophage colony-stimulating factor biosynthetic process	Cytokine-cytokine receptor interaction
223908_at	-0.481	4.374	-2.771	1.412e-02	0.190	-3.037	HDAC8	histone deacetylase 8	X	-71466090	AF212246	55869	Xq13	Hs.310536	23	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter nuclear chromosome histone deacetylase activity nucleus cytoplasm chromatin assembly or disassembly transcription factor binding chromatin modification histone deacetylation hydrolase activity regulation of transcription
222529_at	-0.557	6.820	-2.771	1.412e-02	0.190	-3.037	SLC25A37	solute carrier family 25, member 37	8	23442307	BG251467	51312	8p21.2	Hs.596025 Hs.658208 Hs.716436	11	binding iron ion binding mitochondrion mitochondrial inner membrane ion transport iron ion transport membrane integral to membrane
1562074_a_at	-0.278	3.995	-2.771	1.413e-02	0.190	-3.038	UNC13C	unc-13 homolog C (C. elegans)	15	52092392	BC039494	440279	15q21.3	Hs.657273	4	cytoplasm plasma membrane exocytosis intracellular signaling cascade synaptic transmission zinc ion binding diacylglycerol binding cell junction synapse metal ion binding
244747_at	0.243	3.078	2.771	1.413e-02	0.190	-3.038	NPNT	nephronectin	4	107036053	BF844056	255743	4q24	Hs.518921	5	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development membrane cell differentiation
219929_s_at	0.329	6.247	2.771	1.414e-02	0.190	-3.038	ZFYVE21	zinc finger, FYVE domain containing 21	14	103251897	NM_024071	79038	14q32.33	Hs.592322	4	zinc ion binding metal ion binding
201898_s_at	-0.270	8.762	-2.771	1.414e-02	0.190	-3.038	UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	X	118592526, 118598325	AI126625	7319	Xq24-q25	Hs.379466	16	nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination	Ubiquitin mediated proteolysis
225959_s_at	-0.591	8.177	-2.771	1.414e-02	0.190	-3.038	ZNRF1	zinc and ring finger 1	16	73590415	BF432625	84937	16q23.1	Hs.427284	11	protein binding lysosome endosome zinc ion binding membrane ligase activity modification-dependent protein catabolic process cell junction cytoplasmic vesicle synapse metal ion binding
203879_at	0.285	5.436	2.771	1.414e-02	0.190	-3.039	PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	1	9634376	U86453	5293	1p36.2	Hs.518451	40	nucleotide binding inositol or phosphatidylinositol kinase activity protein binding ATP binding phosphoinositide 3-kinase complex protein amino acid phosphorylation signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
200597_at	-0.384	7.237	-2.770	1.415e-02	0.190	-3.039	EIF3A	eukaryotic translation initiation factor 3, subunit A	10	-120784530	AI123320	8661	10q26	Hs.523299	38	formation of translation initiation complex translation initiation factor activity translation initiation factor activity structural molecule activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex
205569_at	0.549	4.122	2.770	1.415e-02	0.190	-3.039	LAMP3	lysosomal-associated membrane protein 3	3	-184322696	NM_014398	27074	3q26.3-q27	Hs.518448	13	lysosomal membrane cell proliferation membrane integral to membrane	Lysosome
221776_s_at	-0.460	6.451	-2.770	1.416e-02	0.190	-3.040	BRD7	bromodomain containing 7	16	-48910441	AI885109	29117	16q12	Hs.437894	22	nucleus cytoplasm regulation of transcription from RNA polymerase II promoter transcription factor binding Wnt receptor signaling pathway histone binding
223400_s_at	-0.552	3.704	-2.770	1.416e-02	0.190	-3.040	PBRM1	polybromo 1	3	-52554407, -52554407	AF197569	55193	3p21	Hs.189920	19	nuclear chromosome DNA binding chromatin binding protein binding nucleus chromatin remodeling mitosis regulation of transcription
201628_s_at	-0.294	9.819	-2.768	1.421e-02	0.191	-3.043	RRAGA	Ras-related GTP binding A	9	19039371	NM_006570	10670	9p22.1	Hs.432330	10	nucleotide binding GTP binding nucleus cytoplasm Golgi apparatus apoptosis cell death virus-host interaction protein homodimerization activity interspecies interaction between organisms positive regulation of cytolysis protein heterodimerization activity phosphoprotein binding
221020_s_at	-0.334	6.232	-2.768	1.422e-02	0.191	-3.043	SLC25A32	solute carrier family 25, member 32	8	-104480042	NM_030780	81034	8q22.3	Hs.607819	6	transporter activity binding mitochondrion mitochondrial inner membrane transport folic acid transporter activity folic acid transport membrane integral to membrane
224445_s_at	0.262	7.772	2.767	1.423e-02	0.191	-3.044	ZFYVE21	zinc finger, FYVE domain containing 21	14	103251897	BC005999	79038	14q32.33	Hs.592322	4	zinc ion binding metal ion binding
210189_at	-0.311	6.276	-2.767	1.424e-02	0.191	-3.045	HSPA1L	heat shock 70kDa protein 1-like	6	-31885374, -3223483, -3024990	D85730	3305	6p21.3	Hs.690634	62	nucleotide binding ATP binding response to unfolded protein	MAPK signaling pathway Endocytosis Antigen processing and presentation
244499_at	0.232	5.446	2.767	1.425e-02	0.191	-3.045	ZFC3H1	zinc finger, C3H1-type containing	12	-70289648	AI015547	196441	12q21.1	Hs.527874	4	binding intracellular RNA processing zinc ion binding metal ion binding
227127_at	-0.285	6.114	-2.767	1.425e-02	0.191	-3.046	TMEM110	transmembrane protein 110	3	-52848937	BF222855	375346	3p21.1	Hs.705605	2	molecular_function cellular_component biological_process membrane integral to membrane
218569_s_at	-0.407	5.940	-2.766	1.426e-02	0.191	-3.046	KBTBD4	kelch repeat and BTB (POZ) domain containing 4	11	-47550325, -47550325	NM_018095	55709	11p11.2	Hs.656205 Hs.718483	6	protein binding
207125_at	0.229	2.535	2.766	1.427e-02	0.191	-3.047	ZNF225	zinc finger protein 225	19	49309387	NM_013362	7768	19q13.2	Hs.279567	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204247_s_at	0.298	6.258	2.766	1.427e-02	0.191	-3.047	CDK5	cyclin-dependent kinase 5	7	-150381831	NM_004935	1020	7q36	Hs.647078	132	nucleotide binding neuron migration synaptic transmission, dopaminergic p53 binding cyclin-dependent protein kinase activity ErbB-2 class receptor binding ATP binding nucleus cytoplasm cytosol protein amino acid phosphorylation intracellular protein transport cell-matrix adhesion axonogenesis skeletal muscle tissue development motor axon guidance cell proliferation associative learning visual learning embryonic development Schwann cell development membrane transferase activity sensory perception of pain cerebellar cortex development cerebellar cortex formation hippocampus development layer formation in the cerebral cortex central nervous system neuron development cerebral cortex development corpus callosum development lamellipodium filopodium neuron differentiation regulation of cell migration axon dendrite growth cone acetylcholine receptor activator activity neuron projection development negative regulation of protein ubiquitination neuromuscular junction negative regulation of synaptic plasticity receptor catabolic process serine phosphorylation of STAT3 protein synaptic transmission, glutamatergic cell soma receptor clustering ErbB-3 class receptor binding positive regulation of neuron apoptosis negative regulation of cell cycle positive regulation of protein kinase activity positive regulation of calcium ion-dependent exocytosis negative regulation of protein export from nucleus behavioral response to cocaine dendrite morphogenesis tau-protein kinase activity cell division regulation of excitatory postsynaptic membrane potential	Axon guidance Alzheimer's disease
1559114_a_at	0.194	3.878	2.766	1.427e-02	0.191	-3.047	CXCR7	chemokine (C-X-C motif) receptor 7	2	237143118	BC038720	57007	2q37.3	Hs.471751	21	receptor activity G-protein coupled receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane interspecies interaction between organisms
227075_at	-0.494	7.325	-2.765	1.429e-02	0.191	-3.048	ELP3	elongation protein 3 homolog (S. cerevisiae)	8	28006502	AI949204	55140	8p21.1	Hs.491336	22	DNA binding histone acetyltransferase activity iron ion binding protein binding nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter transcription elongation factor complex N-acetyltransferase activity metabolic process acyltransferase activity phosphorylase kinase regulator activity DNA-directed RNA polymerase II, holoenzyme transferase activity RNA polymerase II transcription elongation factor activity regulation of transcription metal ion binding iron-sulfur cluster binding
208030_s_at	-0.287	9.705	-2.765	1.430e-02	0.191	-3.049	ADD1	adducin 1 (alpha)	4	2815381	NM_001119	118	4p16.3	Hs.183706 Hs.701490	139	calmodulin binding nucleus cytoplasm cytosol cytoskeleton plasma membrane transcription factor binding F-actin capping protein complex actin cytoskeleton organization spectrin binding positive regulation of protein binding protein homodimerization activity metal ion binding protein heterodimerization activity actin filament binding barbed-end actin filament capping actin filament bundle formation
216197_at	0.280	4.660	2.764	1.432e-02	0.191	-3.050	ATF7IP	activating transcription factor 7 interacting protein	12	14409877	AK021569	55729	12p13.1	Hs.714407	17	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding nucleus transcription factor complex cytoplasm DNA methylation ATPase activity interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent regulation of transcriptional preinitiation complex assembly
216189_at	0.441	3.041	2.763	1.435e-02	0.192	-3.052	LOC100289109	hypothetical protein LOC100289109	5		BC002465	100289109	5q14.1	Hs.406869
223200_s_at	-0.510	6.350	-2.763	1.436e-02	0.192	-3.052	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	3	-195842806	AI219740	55341	3q29	Hs.518505	12	nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export
234284_at	0.218	3.864	2.763	1.436e-02	0.192	-3.052	GNG8	guanine nucleotide binding protein (G protein), gamma 8	19	-51829172	AF188179	94235	19q13.2-q13.3	Hs.283961	5	GTPase activity signal transducer activity extracellular region heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
213361_at	0.325	5.305	2.763	1.436e-02	0.192	-3.052	TDRD7	tudor domain containing 7	9	99214122	AW129593	23424	9q22.33	Hs.193842	8	nucleic acid binding cytoplasm mitochondrial matrix germ cell development ribonucleoprotein complex P granule protein N-terminus binding
209141_at	-0.623	9.966	-2.763	1.436e-02	0.192	-3.053	UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	17	-4119260	AW299555	7326	17p13.2 1q42	Hs.714345	12	nucleotide binding ubiquitin-protein ligase activity ATP binding ubiquitin-dependent protein catabolic process ligase activity post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
216892_at	0.233	5.147	2.762	1.438e-02	0.192	-3.054	IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)	14		S65761	3500	14q32.33	Hs.510635	29	antigen binding protein binding extracellular region membrane fraction immune response
218239_s_at	-0.535	7.457	-2.762	1.438e-02	0.192	-3.054	GTPBP4	GTP binding protein 4	10	1024348	NM_012341	23560	10p15-p14	Hs.215766	10	regulation of cyclin-dependent protein kinase activity nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization
213198_at	-0.242	8.138	-2.762	1.439e-02	0.192	-3.054	ACVR1B	activin A receptor, type IB	12	50631752, 50631752, 50631752	AL117643	91	12q13	Hs.438918	39	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding in utero embryonic development hair follicle development protein serine/threonine kinase activity receptor activity ATP binding integral to plasma membrane induction of apoptosis signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway embryonic development cell surface membrane activin receptor activity, type I transferase activity peptidyl-threonine phosphorylation growth factor binding manganese ion binding negative regulation of cell growth ubiquitin protein ligase binding positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of erythrocyte differentiation SMAD binding protein amino acid autophosphorylation activin binding	MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia
221516_s_at	0.230	7.080	2.762	1.439e-02	0.192	-3.054	SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	22	38228229	BC002587	54471	22q13	Hs.718449	11	mitochondrion membrane integral to membrane
219171_s_at	-0.348	4.011	-2.762	1.439e-02	0.192	-3.055	ZNF236	zinc finger protein 236	18	72665103	NM_007345	7776	18q22-q23	Hs.719137	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225835_at	-1.061	7.477	-2.762	1.440e-02	0.192	-3.055	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2	5	127447381	AK025062	6558	5q23.3	Hs.162585 Hs.712970	29	transporter activity membrane fraction integral to plasma membrane ion transport potassium ion transport sodium ion transport sodium:potassium:chloride symporter activity symporter activity membrane transepithelial chloride transport potassium ion binding sodium ion binding ammonia transporter activity transepithelial ammonium transport	Vibrio cholerae infection
215040_at	0.330	6.661	2.762	1.440e-02	0.192	-3.055	RNASEH2B	ribonuclease H2, subunit B	13	50381892, 50381892	AL049218	79621	13q14.3	Hs.306291	13	nucleus	DNA replication
208735_s_at	-0.489	7.072	-2.761	1.441e-02	0.192	-3.056	CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	12	-56499976	AF022231	10106	12q13-q15	Hs.524530	11	phosphoprotein phosphatase activity soluble fraction nucleus hydrolase activity
201514_s_at	-0.613	6.900	-2.761	1.442e-02	0.192	-3.056	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5	151131668	NM_005754	10146	5q33.1	Hs.587054	27	nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity
211984_at	-0.373	10.402	-2.760	1.443e-02	0.192	-3.057	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	AI653730	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
219299_at	-0.369	6.364	-2.760	1.444e-02	0.192	-3.057	TRMT12	tRNA methyltransferase 12 homolog (S. cerevisiae)	8	125532228	NM_017956	55039	8q24.13	Hs.9925	9	tRNA processing methyltransferase activity transferase activity
222576_s_at	0.210	5.392	2.760	1.444e-02	0.192	-3.057	EIF2C1	eukaryotic translation initiation factor 2C, 1	1	36121396	AW071829	26523	1p35-p34	Hs.22867	26	cytoplasmic mRNA processing body nuclear-transcribed mRNA catabolic process RNA binding protein binding cytoplasm regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation regulation of transcription
204219_s_at	-0.269	10.248	-2.760	1.445e-02	0.192	-3.058	PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	14	89792646	NM_002802	5700	14q32.11	Hs.356654	51	nucleotide binding proteasome complex protein binding ATP binding nucleus nucleolus cytoplasm cytosol hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
209651_at	0.480	6.944	2.759	1.446e-02	0.192	-3.059	TGFB1I1	transforming growth factor beta 1 induced transcript 1	16	31390984, 31392026	BC001830	7041	16p11.2	Hs.513530	51	transcription coactivator activity transcription coactivator activity protein binding intracellular nucleus cytoplasm cytoskeleton focal adhesion transcription from RNA polymerase II promoter cell adhesion zinc ion binding negative regulation of cell proliferation positive regulation of epithelial to mesenchymal transition Wnt receptor signaling pathway nuclear matrix cell junction cell differentiation positive regulation of transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway androgen receptor signaling pathway ubiquitin-dependent SMAD protein catabolic process positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding androgen receptor binding I-SMAD binding
225644_at	-0.693	7.384	-2.759	1.447e-02	0.192	-3.059	CCDC117	coiled-coil domain containing 117	22	27498661	BF060776	150275	22q12.1	Hs.406460	6
218583_s_at	-0.315	8.112	-2.759	1.447e-02	0.192	-3.060	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	3	-184143252	NM_020640	54165	3q26.3	Hs.715661	16	molecular_function cellular_component biological_process modification-dependent protein catabolic process
218195_at	-0.454	7.133	-2.759	1.447e-02	0.192	-3.060	C6orf211	chromosome 6 open reading frame 211	6	151815114	NM_024573	79624	6q25.1	Hs.15929	7	protein binding
225258_at	0.363	6.066	2.759	1.447e-02	0.192	-3.060	FBLIM1	filamin binding LIM protein 1	1	15957841, 15963580, 15964045	AL133035	54751	1p36.21	Hs.530101	16	protein binding cytoplasm cytoskeleton focal adhesion cell cortex cell adhesion zinc ion binding regulation of cell shape cell junction metal ion binding
217904_s_at	0.282	5.796	2.759	1.448e-02	0.192	-3.060	BACE1	beta-site APP-cleaving enzyme 1	11	-116661624	NM_012104	23621	11q23.2-q23.3	Hs.504003	160	aspartic-type endopeptidase activity endosome Golgi apparatus integral to plasma membrane proteolysis membrane protein ectodomain proteolysis peptidase activity beta-aspartyl-peptidase activity membrane beta-amyloid metabolic process	Alzheimer's disease
200816_s_at	-0.237	9.168	-2.759	1.448e-02	0.192	-3.060	PAFAH1B1	platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)	17	2443672	NM_000430	5048	17p13.3	Hs.77318	75	establishment of mitotic spindle orientation astral microtubule kinetochore acrosome assembly neuron migration nucleus cytoplasm centrosome spindle cytosol microtubule microtubule associated complex cell cortex transport cell cycle mitosis synaptic transmission multicellular organismal development nervous system development neuroblast proliferation learning or memory microtubule binding retrograde axon cargo transport heparin binding adult locomotory behavior membrane lipid catabolic process corpus callosum morphogenesis hippocampus development layer formation in the cerebral cortex cerebral cortex development actin cytoskeleton organization cell differentiation microtubule organizing center organization cell leading edge motile primary cilium nonmotile primary cilium nuclear membrane regulation of Rho GTPase activity dynactin binding protein homodimerization activity phospholipase binding dynein binding platelet activating factor metabolic process vesicle transport along microtubule perinuclear region of cytoplasm brain morphogenesis neuromuscular process controlling balance phosphoprotein binding cell division	Ether lipid metabolism Metabolic pathways
228435_at	-0.862	7.657	-2.758	1.450e-02	0.192	-3.061	FEM1A	fem-1 homolog a (C. elegans)	19	4742727	AL530854	55527	19p13.3	Hs.515082	9	ubiquitin-protein ligase activity cytoplasm modification-dependent protein catabolic process regulation of ubiquitin-protein ligase activity
225684_at	0.423	7.020	2.758	1.450e-02	0.192	-3.061	SKA2	spindle and kinetochore associated complex subunit 2	17	-54542089	BG496998	348235	17q22	Hs.463607	7	mitotic anaphase outer kinetochore of condensed chromosome protein binding spindle microtubule cell cycle chromosome segregation microtubule binding regulation of microtubule polymerization or depolymerization cell division
243643_x_at	-0.240	5.274	-2.758	1.451e-02	0.192	-3.062	SLC30A6	solute carrier family 30 (zinc transporter), member 6	2	32244436	AI623693	55676	2p22.3	Hs.23248	7	Golgi apparatus cation transport zinc ion transport zinc ion binding cation transmembrane transporter activity membrane integral to membrane
224843_at	-0.304	4.779	-2.757	1.452e-02	0.192	-3.063	SLAIN2	SLAIN motif family, member 2	4	48038369	AB040891	57606	4p11	Hs.479677	5
201177_s_at	-0.334	9.547	-2.757	1.452e-02	0.192	-3.063	UBA2	ubiquitin-like modifier activating enzyme 2	19	39611107	NM_005499	10054	19q12	Hs.631580	23	nucleotide binding ATP binding nucleus protein modification process enzyme activator activity transcription factor binding small protein activating enzyme activity ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
1554274_a_at	-0.377	5.394	-2.757	1.452e-02	0.192	-3.063	SSH1	slingshot homolog 1 (Drosophila)	12	-107709824, -107709824, -107700595	AB072356	54434	12q24.11	Hs.199763	23	cell morphogenesis actin binding protein tyrosine phosphatase activity protein binding cytoplasm cytoskeleton plasma membrane protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity lamellipodium actin cytoskeleton organization	Regulation of actin cytoskeleton
208777_s_at	-0.282	8.974	-2.757	1.452e-02	0.192	-3.063	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	17	27795614	AF001212	5717	17q11.2	Hs.655396	41	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
226860_at	-0.434	7.564	-2.757	1.453e-02	0.192	-3.063	TMEM19	transmembrane protein 19	12	70366144	AW572609	55266	12q21.1	Hs.688627	4	membrane integral to membrane
220185_at	0.301	5.760	2.757	1.454e-02	0.192	-3.064	SPTBN4	spectrin, beta, non-erythrocytic 4	19	45664965, 45728234	NM_025213	57731	19q13.13	Hs.32706	11	actin binding structural constituent of cytoskeleton protein binding cytoplasm cytoskeleton cell cortex cytoskeletal anchoring at plasma membrane axonogenesis sensory perception of sound adult walking behavior spectrin fertilization vesicle-mediated transport nuclear matrix PML body transmission of nerve impulse axon ankyrin binding adult behavior positive regulation of multicellular organism growth axon hillock actin filament capping
223404_s_at	-0.401	7.473	-2.757	1.455e-02	0.192	-3.064	C1orf25	chromosome 1 open reading frame 25	1	-183353840	AW512122	81627	1q25.2	Hs.107149	6	RNA binding tRNA (guanine-N2-)-methyltransferase activity intracellular behavior tRNA processing zinc ion binding metal ion binding
214321_at	1.237	5.360	2.756	1.456e-02	0.192	-3.065	NOV	nephroblastoma overexpressed gene	8	120497732	BF440025	4856	8q24.1	Hs.235935	40	regulation of cell growth insulin-like growth factor binding extracellular region growth factor activity
230121_at	0.253	3.377	2.756	1.457e-02	0.193	-3.066	C1orf133	chromosome 1 open reading frame 133	1	-208471426	BF508679	574036	1q32.2	Hs.446946	2
218998_at	-0.340	7.265	-2.756	1.457e-02	0.193	-3.066	C9orf6	chromosome 9 open reading frame 6	9	110736493	NM_017832	54942	9q31.3	Hs.29276	2
215121_x_at	0.591	5.938	2.756	1.458e-02	0.193	-3.066	IGL@	immunoglobulin lambda locus	22		AA680302	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
203605_at	-0.343	7.496	-2.755	1.459e-02	0.193	-3.067	SRP54	signal recognition particle 54kDa	14	34521854	NM_003136	6729	14q13.2	Hs.167535	15	nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane, translocation SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition drug binding 7S RNA binding nuclear speck GDP binding endoplasmic reticulum signal peptide binding response to drug ribonucleoprotein binding	Protein export
202696_at	-0.298	8.252	-2.755	1.459e-02	0.193	-3.067	OXSR1	oxidative-stress responsive 1	3	38182029	NM_005109	9943	3p22-p21.3	Hs.475970	21	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation response to oxidative stress protein kinase cascade transferase activity identical protein binding
209252_at	-0.298	7.765	-2.755	1.459e-02	0.193	-3.067	HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)	5	140051201	U18937	23438	5q31.3	Hs.432560	8	nucleotide binding histidine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix histidyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
221854_at	0.362	5.846	2.755	1.460e-02	0.193	-3.067	PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	1	199519202	AI378979	5317	1q32	Hs.497350	26	signal transducer activity protein binding nucleus intermediate filament cell adhesion signal transduction multicellular organismal development intermediate filament binding cell junction desmosome structural constituent of epidermis
226099_at	-0.430	4.569	-2.755	1.460e-02	0.193	-3.068	ELL2	elongation factor, RNA polymerase II, 2	5	-95246557	AI924426	22936	5q15	Hs.192221 Hs.708710	6	RNA polymerase II transcription factor activity nucleus RNA elongation from RNA polymerase II promoter transcription elongation factor complex RNA polymerase II transcription elongation factor activity regulation of transcription
236845_at	0.311	6.102	2.755	1.460e-02	0.193	-3.068	TRIM62	tripartite motif-containing 62	1	-33383590	AI479391	55223	1p35.1	Hs.656006	8	protein binding intracellular zinc ion binding metal ion binding
212930_at	-0.516	6.527	-2.754	1.461e-02	0.193	-3.068	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	12	-88505956	AW576457	490	12q21.3	Hs.506276	38	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
212012_at	0.451	7.015	2.754	1.462e-02	0.193	-3.069	PXDN	peroxidasin homolog (Drosophila)	2	-1614665	BF342851	7837	2p25	Hs.332197	9	peroxidase activity interleukin-1 receptor antagonist activity calcium ion binding protein binding extracellular region immune response response to oxidative stress oxidoreductase activity heme binding hydrogen peroxide catabolic process oxidation reduction
223371_s_at	0.272	5.362	2.754	1.462e-02	0.193	-3.069	DNAJC4	DnaJ (Hsp40) homolog, subfamily C, member 4	11	63754328	BF116164	3338	11q13	Hs.172847	4	membrane fraction protein folding response to unfolded protein membrane integral to membrane heat shock protein binding unfolded protein binding
230661_at	0.209	3.557	2.754	1.463e-02	0.193	-3.069	C8orf84	chromosome 8 open reading frame 84	8	-74139333	AW451999	157869	8q21.11	Hs.439040	3	scavenger receptor activity extracellular region immune response polysaccharide binding
208361_s_at	-0.251	6.380	-2.754	1.463e-02	0.193	-3.069	POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	8	22158563	NM_001722	661	8q21	Hs.148342	10	DNA binding DNA-directed RNA polymerase activity nucleus DNA-directed RNA polymerase III complex transcription transcription from RNA polymerase III promoter	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
238489_at	-0.536	8.692	-2.754	1.463e-02	0.193	-3.070	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	BF575153	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
222523_at	-0.382	6.924	-2.753	1.465e-02	0.193	-3.071	SENP2	SUMO1/sentrin/SMT3 specific peptidase 2	3	186786724	BE622841	59343	3q27.2	Hs.401388	14	protein binding nucleus nuclear pore cytoplasm proteolysis peptidase activity cysteine-type peptidase activity protein transport membrane protein desumoylation SUMO-specific protease activity modification-dependent protein catabolic process regulation of Wnt receptor signaling pathway mRNA transport intracellular protein transmembrane transport	Wnt signaling pathway
204605_at	-0.359	7.241	-2.753	1.466e-02	0.193	-3.071	CGRRF1	cell growth regulator with ring finger domain 1	14	54046336	NM_006568	10668	14q22.2	Hs.59106	5	protein binding response to stress cell cycle cell cycle arrest zinc ion binding negative regulation of cell proliferation negative regulation of cell growth metal ion binding
209078_s_at	0.301	9.081	2.752	1.467e-02	0.193	-3.072	TXN2	thioredoxin 2	22	-35193038	AF276920	25828	22q13.1	Hs.211929	19	nucleolus cytoplasm mitochondrion glycerol ether metabolic process transport electron carrier activity protein disulfide oxidoreductase activity electron transport chain cell redox homeostasis
219220_x_at	0.319	9.069	2.752	1.467e-02	0.193	-3.072	MRPS22	mitochondrial ribosomal protein S22	3	140545550	NM_020191	56945	3q23	Hs.75724	13	molecular_function structural constituent of ribosome protein binding mitochondrion mitochondrial small ribosomal subunit ribosome biological_process
229298_at	-0.490	5.791	-2.752	1.468e-02	0.193	-3.072	KBTBD7	kelch repeat and BTB (POZ) domain containing 7	13	-40663710	BF436101	84078	13q14.11	Hs.63841	9	molecular_function protein binding cellular_component biological_process
204143_s_at	-0.761	6.074	-2.752	1.468e-02	0.193	-3.072	ENOSF1	enolase superfamily member 1	18	-663860, -663860, -662543	NM_017512	55556	18p11.32	Hs.369762 Hs.658550	12	magnesium ion binding cellular_component mitochondrion metabolic process cellular amino acid catabolic process isomerase activity
206742_at	-0.752	6.835	-2.752	1.468e-02	0.193	-3.073	FIGF	c-fos induced growth factor (vascular endothelial growth factor D)	X	-15273638	NM_004469	2277	Xp22.31	Hs.11392	50	angiogenesis platelet-derived growth factor receptor binding extracellular region extracellular region extracellular space multicellular organismal development growth factor activity positive regulation of cell proliferation membrane cell differentiation platelet alpha granule lumen protein homodimerization activity vascular endothelial growth factor receptor 3 binding vascular endothelial growth factor receptor signaling pathway	Cytokine-cytokine receptor interaction mTOR signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer
201664_at	-0.700	6.309	-2.752	1.468e-02	0.193	-3.073	SMC4	structural maintenance of chromosomes 4	3	161600123, 161601040	AL136877	10051	3q26.1	Hs.58992	14	nucleotide binding condensin complex condensin complex protein binding ATP binding nucleus chromosome cytoplasm cell cycle mitotic chromosome condensation protein heterodimerization activity cell division
201516_at	0.368	8.265	2.752	1.469e-02	0.193	-3.073	SRM	spermidine synthase	1	-11037235	NM_003132	6723	1p36-p22	Hs.76244	12	spermidine synthase activity spermidine biosynthetic process transferase activity	Cysteine and methionine metabolism Arginine and proline metabolism beta-Alanine metabolism Glutathione metabolism Metabolic pathways
228020_at	0.237	7.485	2.751	1.470e-02	0.193	-3.074	PTCD3	Pentatricopeptide repeat domain 3	2	86186815	BG055431	55037	2p11.2	Hs.323489 Hs.623885	9	protein binding mitochondrion
221923_s_at	0.588	6.823	2.751	1.470e-02	0.193	-3.074	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	5	170747402, 170747402	AA191576	4869	5q35	Hs.557550	223	transcription coactivator activity RNA binding nucleus nucleoplasm nucleolus cytoplasm nucleosome assembly intracellular protein transport nucleocytoplasmic transport nucleocytoplasmic transport anti-apoptosis response to stress centrosome cycle signal transduction cell aging protein localization negative regulation of cell proliferation negative regulation of centrosome duplication ribonucleoprotein complex Tat protein binding spindle pole centrosome ribosome assembly histone binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding interspecies interaction between organisms protein heterodimerization activity NF-kappaB binding unfolded protein binding positive regulation of NF-kappaB transcription factor activity protein oligomerization
239042_at	-0.335	6.899	-2.751	1.471e-02	0.193	-3.075	TSR1	TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)	17	-2172731	AI282511	55720	17p13.3	Hs.388170	5	protein binding nucleus nucleolus ribosome assembly
242864_at	0.269	5.524	2.751	1.472e-02	0.193	-3.075	ZNF554	zinc finger protein 554	19	2770871	AI924872	115196	19p13.3	Hs.307043	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1553727_at	0.281	6.414	2.750	1.474e-02	0.193	-3.076	B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3	12	439803	NM_173593	283358	12p13.33	Hs.504416	6	Golgi apparatus membrane integral to membrane transferase activity Golgi cisterna membrane N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
210932_s_at	-0.398	4.046	-2.749	1.477e-02	0.194	-3.078	RNF6	ring finger protein (C3H2C3 type) 6	13	-25684904, -25684904, -25684904	AF293342	6049	13q12.2	Hs.136885	7	protein binding cellular_component biological_process zinc ion binding metal ion binding
222936_s_at	-0.255	2.867	-2.749	1.478e-02	0.194	-3.079	PPPDE1	PPPDE peptidase domain containing 1	1	242882974	AF151904	51029	1q44	Hs.498317	5
200802_at	0.610	8.876	2.749	1.478e-02	0.194	-3.079	SARS	seryl-tRNA synthetase	1	109558062	NM_006513	6301	1p13.3-p13.1	Hs.531176	14	nucleotide binding RNA binding serine-tRNA ligase activity protein binding ATP binding cytoplasm seryl-tRNA aminoacylation tRNA processing ligase activity	Aminoacyl-tRNA biosynthesis
212231_at	-0.348	7.872	-2.748	1.478e-02	0.194	-3.079	FBXO21	F-box protein 21	12	-116065967	AB020682	23014	12q24.22	Hs.719089	7	ubiquitin ligase complex ubiquitin-protein ligase activity ubiquitin-dependent protein catabolic process
219829_at	0.405	8.831	2.748	1.479e-02	0.194	-3.079	ITGB1BP2	integrin beta 1 binding protein (melusin) 2	X	70438352	NM_012278	26548	Xq12-q13.1	Hs.109999	5	calcium ion binding protein binding signal transduction muscle organ development zinc ion binding SH3 domain binding Z disc
222619_at	-0.443	6.840	-2.748	1.481e-02	0.194	-3.081	ZNF281	zinc finger protein 281	1	-198642042	AU150752	23528	1q32.1	Hs.59757	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex zinc ion binding regulation of transcription metal ion binding
222731_at	-0.502	8.411	-2.747	1.482e-02	0.194	-3.081	ZDHHC2	zinc finger, DHHC-type containing 2	8	17058206	AK001608	51201	8p21.3-p22	Hs.443852	8	zinc ion binding membrane integral to membrane palmitoyltransferase activity transferase activity protein palmitoylation metal ion binding
239025_at	0.360	4.658	2.747	1.482e-02	0.194	-3.081	MGC21881	hypothetical locus MGC21881	9	-41942398, 66293050	N71863	389741	9q21.11	Hs.380240 Hs.459704	3
221539_at	0.542	7.538	2.747	1.483e-02	0.194	-3.082	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	8	38007176	AB044548	1978	8p12	Hs.411641	107	protein binding cytosol eukaryotic initiation factor 4E binding insulin receptor signaling pathway negative regulation of translational initiation	ErbB signaling pathway mTOR signaling pathway Insulin signaling pathway Acute myeloid leukemia
230893_at	-0.690	6.116	-2.747	1.483e-02	0.194	-3.082	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21	5	34965454	AI223870	134218	5p13.2	Hs.131887	5	nucleic acid binding intracellular zinc ion binding heat shock protein binding metal ion binding
205512_s_at	-0.364	8.186	-2.747	1.484e-02	0.194	-3.083	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	X	-129091019, -129091019, -129091018	NM_004208	9131	Xq25-q26	Hs.424932	58	DNA binding protein binding nucleus cytoplasm mitochondrion mitochondrial intermembrane space DNA fragmentation involved in apoptosis apoptosis DNA damage response, signal transduction resulting in induction of apoptosis electron carrier activity oxidoreductase activity cell redox homeostasis FAD binding oxidation reduction	Apoptosis
212989_at	-0.456	5.201	-2.746	1.486e-02	0.194	-3.084	SGMS1	sphingomyelin synthase 1	10	-51735350	AI377497	259230	10q11.2	Hs.654698	18	Golgi trans cisterna protein binding nucleus endoplasmic reticulum Golgi apparatus plasma membrane lipid metabolic process sphingolipid metabolic process sphingomyelin biosynthetic process inflammatory response integral to membrane cell growth kinase activity transferase activity integral to Golgi membrane sphingomyelin synthase activity negative regulation of apoptosis ceramide cholinephosphotransferase activity	Sphingolipid metabolism Metabolic pathways
212779_at	-0.887	9.309	-2.746	1.486e-02	0.194	-3.084	KIAA1109	KIAA1109	4	123311207	AB029032	84162	4q27	Hs.408142	12	membrane integral to membrane
205349_at	0.219	4.682	2.746	1.487e-02	0.194	-3.084	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	19	3087190	NM_002068	2769	19p13.3	Hs.73797	28	nucleotide binding GTPase activity signal transducer activity GTP binding heterotrimeric G-protein complex plasma membrane protein amino acid ADP-ribosylation signal transduction elevation of cytosolic calcium ion concentration activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway guanyl nucleotide binding	Calcium signaling pathway
218825_at	0.347	6.594	2.746	1.487e-02	0.194	-3.084	EGFL7	EGF-like-domain, multiple 7	9	138677197, 138677202	NM_016215	51162	9q34.3	Hs.91481	12	angiogenesis blood vessel development vasculogenesis calcium ion binding extracellular region extracellular space multicellular organismal development negative regulation of cell migration
218145_at	1.154	5.963	2.745	1.489e-02	0.194	-3.085	TRIB3	tribbles homolog 3 (Drosophila)	20	309307	NM_021158	57761	20p13-p12.2	Hs.516826	36	transcription corepressor activity protein kinase activity protein kinase inhibitor activity protein binding protein binding ATP binding nucleus nucleolus protein amino acid phosphorylation negative regulation of protein kinase activity apoptosis response to stress protein kinase binding protein kinase binding regulation of MAP kinase activity regulation of transcription
222892_s_at	0.291	5.275	2.745	1.490e-02	0.194	-3.086	TMEM40	transmembrane protein 40	3	-12750391	AI087937	55287	3p25.2	Hs.475502	4	membrane integral to membrane
244581_at	-0.377	5.760	-2.745	1.490e-02	0.194	-3.086	ZBTB20	zinc finger and BTB domain containing 20	3	-115540212	AI828036	26137	3q13.2	Hs.655108	13	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
227582_at	0.364	6.611	2.744	1.491e-02	0.194	-3.087	KLHDC9	kelch domain containing 9	1	159334777	AW079843	126823	1q23.3	Hs.507290	3
217113_at	0.309	4.835	2.744	1.492e-02	0.194	-3.087	AMACR	alpha-methylacyl-CoA racemase	5	-34023656	AK022765	23600	5p13	Hs.508343	53	mitochondrion peroxisome alpha-methylacyl-CoA racemase activity metabolic process isomerase activity	Primary bile acid biosynthesis Metabolic pathways
221911_at	0.477	2.782	2.744	1.492e-02	0.195	-3.087	ETV1	ets variant 1	7	-13897382, -13897382, -13897382, -13897382	BE881590	2115	7p21.3	Hs.22634	33	transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding
AFFX-HSAC07/X00351_5_at	-0.264	11.188	-2.743	1.494e-02	0.195	-3.089	ACTB	actin, beta	7	-5533304	AFFX-HSAC07/X00351_5	60	7p15-p12	Hs.520640 Hs.708120	206	nucleotide binding structural constituent of cytoskeleton protein binding ATP binding soluble fraction cytoplasm cytosol cell motion cortical cytoskeleton NuA4 histone acetyltransferase complex nitric-oxide synthase binding MLL5-L complex	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
215102_at	0.268	4.330	2.743	1.495e-02	0.195	-3.089	DPY19L1P1	dpy-19-like 1 pseudogene 1 (C. elegans)	7		AK026768	100129460	7p14.3	Hs.633705
206332_s_at	0.500	6.052	2.743	1.495e-02	0.195	-3.089	IFI16	interferon, gamma-inducible protein 16	1	157246305	NM_005531	3428	1q22	Hs.380250	42	DNA binding double-stranded DNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm regulation of transcription, DNA-dependent cell proliferation response to virus transcription repressor activity myeloid cell differentiation monocyte differentiation DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
227085_at	0.272	7.224	2.743	1.495e-02	0.195	-3.089	H2AFV	H2A histone family, member V	7	-44839737, -44833012	AI823792	94239	7p13	Hs.488189	12	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
202467_s_at	-0.432	9.905	-2.743	1.496e-02	0.195	-3.090	COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	15	-47204762	NM_004236	9318	15q21.2	Hs.369614	37	signal transducer activity protein binding protein binding nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter signal transduction signalosome
223821_s_at	0.336	3.157	2.742	1.497e-02	0.195	-3.090	SUSD4	sushi domain containing 4	1	-221474874, -221460783	BC004888	55061	1q41	Hs.497841	4	membrane integral to membrane
219581_at	-0.416	5.782	-2.742	1.498e-02	0.195	-3.091	TSEN2	tRNA splicing endonuclease 2 homolog (S. cerevisiae)	3	12500930, 12501009, 12501009	NM_025265	80746	3p25.2	Hs.335550	12	tRNA-intron endonuclease activity tRNA-intron endonuclease complex nucleic acid binding endonuclease activity nucleus nucleolus tRNA splicing, via endonucleolytic cleavage and ligation mRNA processing hydrolase activity
226483_at	-0.400	4.358	-2.742	1.499e-02	0.195	-3.091	TMEM68	transmembrane protein 68	8	-56813873	AI890761	137695	8q12.1	Hs.420076	3	metabolic process acyltransferase activity membrane integral to membrane
202846_s_at	-0.331	6.658	-2.741	1.500e-02	0.195	-3.092	PIGC	phosphatidylinositol glycan anchor biosynthesis, class C	1	-170677219	NM_002642	5279	1q23-q25	Hs.188456	12	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring glycosyl groups phosphatidylinositol N-acetylglucosaminyltransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
225619_at	-0.435	3.022	-2.741	1.500e-02	0.195	-3.092	SLAIN1	SLAIN motif family, member 1	13	77170470, 77213295	AV730849	122060	13q22.3	Hs.349955	4
223344_s_at	0.281	5.574	2.741	1.501e-02	0.195	-3.093	MS4A7	membrane-spanning 4-domains, subfamily A, member 7	11	59902533	AB026043	58475	11q12	Hs.530735	10	receptor activity signal transduction membrane integral to membrane
207667_s_at	-0.325	7.771	-2.741	1.502e-02	0.195	-3.094	MAP2K3	mitogen-activated protein kinase kinase 3	17	21128560, 21135373	NM_002756	5606	17q11.2	Hs.514012	45	nucleotide binding activation of MAPK activity protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding inflammatory response signal transduction transferase activity regulation of cytokine biosynthetic process positive regulation of protein kinase activity positive regulation of transcription, DNA-dependent cardiac muscle contraction	MAPK signaling pathway Toll-like receptor signaling pathway Fc epsilon RI signaling pathway GnRH signaling pathway Amyotrophic lateral sclerosis (ALS)
232696_at	0.374	3.719	2.741	1.502e-02	0.195	-3.094	LOC648556	uncharacterized gastric protein ZA43P	16		AI394334	648556		Hs.203594
227525_at	-0.511	5.871	-2.740	1.503e-02	0.195	-3.094	GLCCI1	glucocorticoid induced transcript 1	7	7974947	AA058770	113263	7p21.3	Hs.131673	9
226338_at	-0.507	6.736	-2.740	1.503e-02	0.195	-3.094	TMEM55A	transmembrane protein 55A	8	-92075674	AA604382	55529	8q21.3	Hs.202517	4	lysosome endosome membrane integral to membrane hydrolase activity
213556_at	0.331	5.438	2.739	1.506e-02	0.195	-3.096	LOC390940	similar to R28379_1	19		BE673445	390940	19q13.31	Hs.22049	1	phospholipase inhibitor activity extracellular region
200927_s_at	-0.495	7.252	-2.739	1.507e-02	0.195	-3.096	RAB14	RAB14, member RAS oncogene family	9	-122980236	AA919115	51552	9q32-q34.11	Hs.371563 Hs.713585	19	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm
205169_at	-0.495	5.198	-2.739	1.507e-02	0.195	-3.096	RBBP5	retinoblastoma binding protein 5	1	-203322601	NM_005057	5929	1q32	Hs.519230	11	protein binding nucleus histone methyltransferase complex
215233_at	-0.552	7.204	-2.738	1.509e-02	0.196	-3.097	JMJD6	jumonji domain containing 6	17	-72226119, -72220508	AA351360	23210	17q25	Hs.514505	21	blood vessel development kidney development receptor activity nucleus plasma membrane apoptosis cell surface receptor linked signal transduction multicellular organismal development heart development oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine cell differentiation lung development T cell differentiation in the thymus histone demethylase activity (H3-R2 specific) histone demethylase activity (H4-R3 specific) macrophage activation identical protein binding recognition of apoptotic cell regulation of nuclear mRNA splicing, via spliceosome erythrocyte development oxidation reduction retina development in camera-type eye histone H3-R2 demethylation histone H4-R3 demethylation peptidyl-lysine 5-dioxygenase activity
1562239_at	0.310	4.648	2.738	1.510e-02	0.196	-3.098	SGSM1	small G protein signaling modulator 1	22	23532135	AB075821	129049	22q11.23	Hs.474397 Hs.620906	5	Rab GTPase activator activity intracellular Golgi apparatus regulation of Rab GTPase activity
214339_s_at	0.304	5.609	2.738	1.511e-02	0.196	-3.099	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	19	-43770120	AA744529	11184	19q13.1-q13.4	Hs.95424	29	nucleotide binding activation of MAPKKK activity protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding response to stress protein kinase cascade activation of JUN kinase activity MAP kinase kinase kinase kinase activity transferase activity peptidyl-serine phosphorylation	MAPK signaling pathway
226894_at	-0.527	5.769	-2.738	1.511e-02	0.196	-3.099	SLC35A3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3	1	100208127	BE501976	23443	1p21	Hs.448979	8	Golgi membrane nucleotide-sugar transmembrane transporter activity sugar:hydrogen symporter activity UDP-N-acetylglucosamine transmembrane transporter activity Golgi apparatus UDP-N-acetylglucosamine metabolic process nucleotide-sugar transport UDP-N-acetylglucosamine transport membrane integral to membrane
1552878_at	0.201	2.230	2.738	1.512e-02	0.196	-3.099	ATOH7	atonal homolog 7 (Drosophila)	10	-69660387	BC032621	220202	10q21.3 10q21.3-q22.1	Hs.175396	4	DNA binding nucleus multicellular organismal development nervous system development circadian rhythm entrainment of circadian clock cell differentiation transcription regulator activity regulation of transcription
238802_at	0.314	4.363	2.737	1.513e-02	0.196	-3.100	TYSND1	trypsin domain containing 1	10	-71567738	AA470128	219743	10q22.1	Hs.533655	3	serine-type endopeptidase activity peroxisome proteolysis peptidase activity
227037_at	-0.365	5.565	-2.737	1.513e-02	0.196	-3.100	PLD6	phospholipase D family, member 6	17	-17045033	AA029500	201164	17p11.2	Hs.31652	2	phospholipase D activity metabolic process membrane integral to membrane lipid catabolic process hydrolase activity NAPE-specific phospholipase D activity
208640_at	-0.299	10.558	-2.737	1.513e-02	0.196	-3.100	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	7	6380650	BG292367	5879	7p22	Hs.413812	406	nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst	MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer
229622_at	0.518	5.148	2.737	1.514e-02	0.196	-3.100	FAM132B	family with sequence similarity 132, member B	2		H16258	151176	2q37.3	Hs.24951	2	extracellular region
208983_s_at	0.476	6.004	2.737	1.514e-02	0.196	-3.101	PECAM1	platelet/endothelial cell adhesion molecule	17	-59753594	M37780	5175	17q23	Hs.514412 Hs.718947	147	protein binding extracellular space plasma membrane plasma membrane cell adhesion signal transduction cell recognition integral to membrane platelet alpha granule membrane	Cell adhesion molecules (CAMs) Leukocyte transendothelial migration
217525_at	0.383	5.631	2.736	1.516e-02	0.196	-3.102	OLFML1	olfactomedin-like 1	11	7463330	AW305097	283298	11p15.4	Hs.503500	5	extracellular region
228963_at	-0.366	6.202	-2.736	1.517e-02	0.196	-3.102	RSBN1L	round spermatid basic protein 1-like	7	77163678	BE856028	222194	7q11.23	Hs.592289 Hs.72451	4	nucleus
231781_s_at	-0.687	9.640	-2.735	1.519e-02	0.196	-3.103	LRRC2	leucine rich repeat containing 2	3	-46531881, -46531881	AK021919	79442	3p21.31	Hs.657345	7	protein binding
238406_x_at	0.300	6.238	2.735	1.519e-02	0.196	-3.104	SEZ6L2	seizure related 6 homolog (mouse)-like 2	16	-29789980	AI734001	26470	16p11.2	Hs.6314	10	endoplasmic reticulum plasma membrane integral to membrane
217645_at	-0.334	6.272	-2.735	1.521e-02	0.196	-3.105	COX16	COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)	14	-69861551	AW088547	51241	14q24.2	Hs.709581	5	mitochondrion membrane integral to membrane mitochondrial membrane
231185_at	0.277	5.098	2.734	1.522e-02	0.196	-3.105	KIAA1161	KIAA1161	9	-34358906	AI479773	57462	9p13.3	Hs.522083	3	hydrolase activity, hydrolyzing O-glycosyl compounds carbohydrate metabolic process metabolic process membrane integral to membrane
206553_at	0.262	4.702	2.734	1.522e-02	0.196	-3.105	OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	12	111900656, 111900656, 111900656	NM_002535	4939	12q24.2	Hs.414332	17	nucleotide binding RNA binding ATP binding nucleus mitochondrion endoplasmic reticulum microsome nucleobase, nucleoside, nucleotide and nucleic acid metabolic process immune response membrane transferase activity nucleotidyltransferase activity
225710_at	0.477	5.845	2.734	1.522e-02	0.196	-3.106	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	3	-180596569	H99792	59345	3q26.33	Hs.173030	18	signal transducer activity signal transduction hormone-mediated signaling	Chemokine signaling pathway
202900_s_at	-0.397	7.026	-2.734	1.522e-02	0.196	-3.106	NUP88	nucleoporin 88kDa	17	-5230143	NM_002532	4927	17p13.2	Hs.584784	24	transporter activity nucleus nuclear pore cytosol protein transport mRNA transport intracellular protein transmembrane transport
214185_at	0.271	4.817	2.733	1.524e-02	0.197	-3.107	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	1	32252077	AW592227	10657	1p32	Hs.709204	86	G2/M transition of mitotic cell cycle DNA binding RNA binding SH3/SH2 adaptor activity protein binding nucleus mRNA processing cell cycle cell cycle arrest cell surface receptor linked signal transduction cell proliferation membrane negative regulation of transcription transcription repressor activity SH3 domain binding regulation of RNA export from nucleus
220349_s_at	0.344	7.377	2.733	1.525e-02	0.197	-3.107	ENGASE	endo-beta-N-acetylglucosaminidase	17	74582613	NM_022759	64772	17q25.3	Hs.29288	5	intracellular cytoplasm cytosol metabolic process hydrolase activity, acting on glycosyl bonds mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	Other glycan degradation
209800_at	0.243	4.933	2.733	1.525e-02	0.197	-3.107	KRT16	keratin 16	17	-37019556	AF061812	3868	17q12-q21	Hs.655160	29	structural constituent of cytoskeleton protein binding intermediate filament cell proliferation epidermis development intermediate filament cytoskeleton organization
201069_at	0.477	6.784	2.733	1.526e-02	0.197	-3.108	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	16	54070581, 54072974	NM_004530	4313	16q13-q21	Hs.513617	587	response to hypoxia blood vessel maturation intramembranous ossification metalloendopeptidase activity calcium ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space plasma membrane proteolysis metabolic process peptidase activity zinc ion binding sarcomere collagen catabolic process intracellular membrane-bounded organelle face morphogenesis bone trabecula formation	Leukocyte transendothelial migration GnRH signaling pathway Pathways in cancer Bladder cancer
1554380_at	-0.204	4.998	-2.733	1.527e-02	0.197	-3.108	NEK11	NIMA (never in mitosis gene a)- related kinase 11	3	132228383, 132228383	AB071997	79858	3q22.1	Hs.657336	8	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding nucleus nucleolus protein amino acid phosphorylation cell cycle protein kinase cascade transferase activity manganese ion binding intra-S DNA damage checkpoint identical protein binding
91816_f_at	0.316	3.547	2.733	1.527e-02	0.197	-3.108	MEX3D	mex-3 homolog D (C. elegans)	19	-1505667	C18318	399664	19p13.3	Hs.436495	4	RNA binding protein binding nucleus cytoplasm zinc ion binding metal ion binding
1568248_x_at	0.234	5.515	2.732	1.527e-02	0.197	-3.109	SNORA71B	small nucleolar RNA, H/ACA box 71B	20	-36487256	Y11166	26776	20q11.23	Hs.400876	2
220626_at	0.245	5.919	2.732	1.529e-02	0.197	-3.110	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	14	-93819402, -93819402	NM_016186	51156	14q32.13	Hs.118620	15	serine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity
39549_at	0.383	4.601	2.732	1.529e-02	0.197	-3.110	NPAS2	neuronal PAS domain protein 2	2	100803044	AI743090	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
32541_at	-0.334	7.208	-2.732	1.530e-02	0.197	-3.110	PPP3CC	protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform	8	22354540	S46622	5533	8p21.3	Hs.655661	21	phosphoprotein phosphatase activity iron ion binding calmodulin binding cytosol zinc ion binding activation of pro-apoptotic gene products hydrolase activity metal ion binding	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
241741_at	-0.605	5.885	-2.731	1.531e-02	0.197	-3.111	CRLS1	cardiolipin synthase 1	20	5934738, 5935897	AI339837	54675	20p13-p12.3	Hs.224764	14	mitochondrion mitochondrial inner membrane phospholipid biosynthetic process membrane integral to membrane transferase activity phosphotransferase activity, for other substituted phosphate groups	Glycerophospholipid metabolism Metabolic pathways
218520_at	-0.361	6.533	-2.731	1.532e-02	0.197	-3.111	TBK1	TANK-binding kinase 1	12	63132203	NM_013254	29110	12q14.1	Hs.505874 Hs.607889	51	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation response to virus transferase activity positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms innate immune response	Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway
203860_at	0.521	6.662	2.731	1.532e-02	0.197	-3.111	PCCA	propionyl Coenzyme A carboxylase, alpha polypeptide	13	99539337	NM_000282	5095	13q32	Hs.80741	29	nucleotide binding propionyl-CoA carboxylase activity ATP binding mitochondrion mitochondrial matrix metabolic process biotin binding ligase activity	Valine, leucine and isoleucine degradation Propanoate metabolism Metabolic pathways
201007_at	0.368	12.162	2.731	1.532e-02	0.197	-3.112	HADHB	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	2	26321119	NM_000183	3032	2p23	Hs.515848	23	3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity mitochondrion mitochondrial envelope mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process acyltransferase activity transferase activity mitochondrial nucleoid	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Metabolic pathways
202979_s_at	-0.585	5.176	-2.730	1.534e-02	0.197	-3.113	CREBZF	CREB/ATF bZIP transcription factor	11	-85046257	NM_021212	58487	11q14	Hs.535319 Hs.595940 Hs.714910	12	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent response to virus negative regulation of transcription specific transcriptional repressor activity sequence-specific DNA binding negative regulation of gene expression, epigenetic regulation of transcription factor activity
228601_at	0.291	4.627	2.730	1.536e-02	0.197	-3.113	LOC401022	hypothetical LOC401022	2		AW340112	401022	2q31.2	Hs.98661	1
1560136_at	-0.267	5.425	-2.729	1.537e-02	0.197	-3.114	ARL5C	ADP-ribosylation factor-like 5C	17	-34566673	BQ027290	390790	17q12	Hs.568007	2	nucleotide binding GTP binding
239835_at	-1.183	3.756	-2.729	1.537e-02	0.197	-3.114	KBTBD8	kelch repeat and BTB (POZ) domain containing 8	3	67131416	AA669114	84541	3p14	Hs.116665	5	protein binding
226224_at	-0.265	7.032	-2.729	1.537e-02	0.197	-3.114	FOXK2	forkhead box K2	17	78070882	AI798846	3607	17q25	Hs.591140	11	magnesium ion binding transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding
204034_at	-0.302	7.331	-2.729	1.538e-02	0.197	-3.115	ETHE1	ethylmalonic encephalopathy 1	19	-48702710	NM_014297	23474	19q13.31	Hs.7486	14	nucleus cytoplasm mitochondrion mitochondrial matrix zinc ion binding hydrolase activity metal ion binding
226263_at	-0.414	6.316	-2.729	1.538e-02	0.197	-3.115	SNRNP48	small nuclear ribonucleoprotein 48kDa (U11/U12)	6	7535430	AA630674	154007	6p24.3	Hs.13366	6	nucleus U12-type spliceosomal complex mRNA processing zinc ion binding RNA splicing metal ion binding
244771_at	-0.385	8.801	-2.728	1.539e-02	0.197	-3.116	KLHDC6	kelch domain containing 6	3	129124591	AI038623	166348	3q21.3	Hs.132087	4	protein binding
205389_s_at	0.437	9.476	2.728	1.541e-02	0.198	-3.117	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	AI659683	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
230196_x_at	0.259	5.909	2.727	1.543e-02	0.198	-3.118	ARHGAP23	Rho GTPase activating protein 23	17	33867169	AI123323	57636	17q12	Hs.374446	4	GTPase activator activity protein binding intracellular signal transduction
1554080_at	-0.417	7.003	-2.727	1.543e-02	0.198	-3.118	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	2	219141921	BC007102	9125	2q35	Hs.148767	6	protein binding nucleus sex differentiation cytokine-mediated signaling pathway regulation of transcription	RNA degradation
202787_s_at	-0.359	7.130	-2.727	1.543e-02	0.198	-3.118	MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3	3	50629604	U43784	7867	3p21.3	Hs.234521	20	nucleotide binding protein serine/threonine kinase activity MAP kinase kinase activity ATP binding nucleus cytoplasm cytosol protein amino acid phosphorylation response to stress intracellular signaling cascade Ras protein signal transduction transferase activity	MAPK signaling pathway VEGF signaling pathway
1559163_at	-0.205	2.220	-2.727	1.544e-02	0.198	-3.119	LOC285954	hypothetical LOC285954	7	41700038, 41700070	AK096266	285954	7p14.1	Hs.656869	2
218442_at	-0.404	7.266	-2.727	1.545e-02	0.198	-3.119	TTC4	tetratricopeptide repeat domain 4	1	54954116	NM_004623	7268	1p32.3	Hs.412482	10	binding
203283_s_at	-0.310	3.089	-2.726	1.546e-02	0.198	-3.119	HS2ST1	heparan sulfate 2-O-sulfotransferase 1	1	87152922, 87152922	AK023260	9653	1p31.1-p22.1	Hs.719144	9	Golgi apparatus membrane integral to membrane transferase activity	Heparan sulfate biosynthesis
226505_x_at	-0.472	8.085	-2.726	1.547e-02	0.198	-3.120	USP32	ubiquitin specific peptidase 32	17	-55609472	AI148567	84669	17q23.1-q23.2	Hs.132868	6	ubiquitin thiolesterase activity calcium ion binding ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity membrane
227430_at	-0.243	5.288	-2.726	1.548e-02	0.198	-3.121	ZC3H10	zinc finger CCCH-type containing 10	12	54798296	AI969773	84872	12q13.2	Hs.632706	7	nucleic acid binding zinc ion binding metal ion binding
204992_s_at	-0.473	10.321	-2.725	1.549e-02	0.198	-3.121	PFN2	profilin 2	3	-151165380	NM_002628	5217	3q25.1-q25.2	Hs.91747	24	actin binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm regulation of actin polymerization or depolymerization actin cytoskeleton actin cytoskeleton organization	Regulation of actin cytoskeleton
205279_s_at	0.539	4.227	2.725	1.549e-02	0.198	-3.121	GLRB	glycine receptor, beta	4	158216726	AF094754	2743	4q31.3	Hs.32973	14	startle response ion channel activity extracellular ligand-gated ion channel activity protein binding membrane fraction plasma membrane integral to plasma membrane ion transport chloride transport neuropeptide signaling pathway synaptic transmission acrosome reaction nervous system development visual perception adult walking behavior glycine binding extracellular-glycine-gated chloride channel activity cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex regulation of membrane potential synapse postsynaptic membrane synaptic transmission, glycinergic righting reflex	Neuroactive ligand-receptor interaction
202955_s_at	-0.320	5.915	-2.725	1.549e-02	0.198	-3.121	ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	8	-68272450	AF084520	10565	8q13	Hs.656902	22	ARF guanyl-nucleotide exchange factor activity binding intracellular exocytosis ARF GTPase activator activity myosin binding regulation of ARF protein signal transduction
206961_s_at	0.240	4.034	2.725	1.551e-02	0.198	-3.122	MED20	mediator complex subunit 20	6	-41981069	NM_004275	9477	6p21.1	Hs.278434	11	DNA-directed RNA polymerase activity protein binding nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity mediator complex regulation of transcription
201020_at	-0.487	7.768	-2.725	1.551e-02	0.198	-3.123	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	22	30670478	NM_003405	7533	22q12.3	Hs.226755	76	actin binding insulin-like growth factor receptor binding cytoplasm glucocorticoid catabolic process intracellular protein transport transcription activator activity enzyme binding protein domain specific binding glucocorticoid receptor binding glucocorticoid receptor signaling pathway regulation of neuron differentiation positive regulation of transcription regulation of synaptic plasticity negative regulation of dendrite morphogenesis	Cell cycle Neurotrophin signaling pathway
214678_x_at	-0.510	6.519	-2.725	1.551e-02	0.198	-3.123	ZFX	zinc finger protein, X-linked	X	24079728	R51161	7543	Xp21.3	Hs.336681	13	DNA binding transcription coactivator activity intracellular nucleus nucleolus zinc ion binding transcription regulator activity regulation of transcription metal ion binding
209904_at	0.337	13.411	2.724	1.552e-02	0.198	-3.123	TNNC1	troponin C type 1 (slow)	3	-52460147	AF020769	7134	3p21.3-p14.3	Hs.118845	48	calcium ion binding troponin complex regulation of muscle contraction troponin I binding troponin T binding regulation of muscle filament sliding speed protein homodimerization activity regulation of ATPase activity calcium-dependent protein binding actin filament binding ventricular cardiac muscle morphogenesis cardiac muscle contraction	Calcium signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
218710_at	-0.269	6.208	-2.724	1.552e-02	0.198	-3.123	TTC27	tetratricopeptide repeat domain 27	2	32706632	NM_017735	55622	2p22.3	Hs.468125	6	protein binding cellular_component biological_process
222408_s_at	-0.348	8.246	-2.724	1.553e-02	0.198	-3.124	YPEL5	yippee-like 5 (Drosophila)	2	30223253	BC000836	51646	2p23.1	Hs.515890	6
211440_x_at	-0.235	3.071	-2.724	1.553e-02	0.198	-3.124	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	7	99263571	AF280110	64816	7q21.1	Hs.306220 Hs.654391 Hs.695915	17	endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	gamma-Hexachlorocyclohexane degradation Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
202501_at	-0.504	7.499	-2.724	1.554e-02	0.198	-3.124	MAPRE2	microtubule-associated protein, RP/EB family, member 2	18	30810889, 30812205, 30875321	NM_014268	10982	18q12.1-q12.2	Hs.532824	27	cytoplasm microtubule cell cycle mitosis signal transduction microtubule binding cell proliferation cell division
205147_x_at	0.313	4.177	2.723	1.556e-02	0.198	-3.125	NCF4	neutrophil cytosolic factor 4, 40kDa	22	35586975	NM_000631	4689	22q13.1	Hs.474781	51	cytoplasm cytosol immune response cell communication membrane phosphoinositide binding NADPH oxidase complex protein dimerization activity oxidation reduction	Leukocyte transendothelial migration
205657_at	0.219	6.751	2.723	1.557e-02	0.198	-3.126	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	2	-42847732	NM_012205	23498	2p21	Hs.368805	12	3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity soluble fraction cytoplasm cytosol cytosol ferrous iron binding electron carrier activity response to zinc ion oxidoreductase activity pyridine nucleotide biosynthetic process NAD metabolic process quinolinate biosynthetic process response to cadmium ion metal ion binding oxidation reduction neuron maintenance	Tryptophan metabolism Metabolic pathways
223023_at	0.260	5.774	2.723	1.557e-02	0.198	-3.126	BET1L	blocked early in transport 1 homolog (S. cerevisiae)-like	11	-192923	BC000688	51272	11p15.5	Hs.414418	14	SNAP receptor activity endosome Golgi apparatus protein transport membrane integral to membrane SNARE complex retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
227190_at	0.427	5.569	2.723	1.558e-02	0.198	-3.126	TMEM37	transmembrane protein 37	2	119905915	N93191	140738	2q14.2	Hs.26216	3	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane
201652_at	-0.226	9.954	-2.722	1.558e-02	0.198	-3.127	COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	8	-68117868	NM_006837	10987	8q13.1	Hs.491912	79	protein deneddylation transcription coactivator activity translation initiation factor activity protein binding nucleus nucleolus cytoplasm eukaryotic translation initiation factor 3 complex transcription from RNA polymerase II promoter translation signalosome peptidase activity metallopeptidase activity metal ion binding regulation of cell cycle
219008_at	0.315	2.769	2.722	1.559e-02	0.198	-3.127	C2orf43	chromosome 2 open reading frame 43	2	-20748298	NM_021925	60526	2p24.1	Hs.187823	1
204159_at	-0.581	7.084	-2.722	1.559e-02	0.198	-3.127	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	1	51206954, 51208229	NM_001262	1031	1p32	Hs.525324 Hs.716664	45	regulation of cyclin-dependent protein kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm induction of apoptosis cell cycle cell cycle arrest negative regulation of cell proliferation protein kinase binding negative regulation of cell growth negative regulation of phosphorylation oligodendrocyte differentiation	Cell cycle
204771_s_at	-0.377	6.755	-2.722	1.561e-02	0.199	-3.128	TTF1	transcription termination factor, RNA polymerase I	9	-134240757	AI632304	7270	9q34.13	Hs.54780	18	DNA binding transcription termination factor activity nucleus nucleoplasm nucleolus transcription termination negative regulation of DNA replication regulation of transcription
201993_x_at	-0.256	8.794	-2.722	1.561e-02	0.199	-3.129	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	NM_005463	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
215898_at	-0.273	3.670	-2.721	1.562e-02	0.199	-3.129	TTLL5	tubulin tyrosine ligase-like family, member 5	14	75197373	AK021879	23093	14q24.3	Hs.709609	7	tubulin-tyrosine ligase activity nucleus cytoplasm cilium microtubule basal body transcription protein modification process ligase activity
221970_s_at	-0.294	7.785	-2.721	1.564e-02	0.199	-3.130	NOL11	nucleolar protein 11	17	63144522	AU158148	25926	17q24.2	Hs.463936	5	nucleus nucleolus
1554579_a_at	-0.505	8.489	-2.720	1.566e-02	0.199	-3.131	MYO18B	myosin XVIIIB	22	24468119	AB042648	84700	22q11.2-q12.1	Hs.417959	11	nucleotide binding motor activity actin binding protein binding ATP binding nucleus cytoplasm unconventional myosin complex sarcomere
1555314_at	0.258	3.178	2.720	1.566e-02	0.199	-3.132	WDR19	WD repeat domain 19	4	38860418	BC032578	57728	4p14	Hs.438482	8	protein binding intracellular protein transport vesicle-mediated transport
208614_s_at	0.406	7.005	2.720	1.567e-02	0.199	-3.132	FLNB	filamin B, beta	3	57969166	M62994	2317	3p14.3	Hs.476448	38	actin binding protein binding cytoplasm cell cortex cytoskeletal anchoring at plasma membrane signal transduction multicellular organismal development muscle organ development actin cytoskeleton integral to membrane Z disc actin cytoskeleton organization cell differentiation	MAPK signaling pathway Focal adhesion
65630_at	0.327	6.360	2.720	1.567e-02	0.199	-3.132	TMEM80	transmembrane protein 80	11	685615	AI742455	283232	11p15.5	Hs.448664	2	membrane integral to membrane
207664_at	0.251	3.052	2.719	1.568e-02	0.199	-3.132	ADAM2	ADAM metallopeptidase domain 2	8	-39720411	NM_001464	2515	8p11.2	Hs.177959	12	metalloendopeptidase activity integrin binding protein binding integral to plasma membrane proteolysis cell adhesion fusion of sperm to egg plasma membrane zinc ion binding visual learning membrane adult behavior
229674_at	0.292	4.617	2.719	1.570e-02	0.199	-3.133	SERTAD4	SERTA domain containing 4	1	208472817	AL035414	56256	1q32.1-q41	Hs.600545	2
223418_x_at	-0.463	5.921	-2.718	1.572e-02	0.199	-3.135	ANKRD13C	ankyrin repeat domain 13C	1	-70497272	AL136717	81573	1p32.3-p31.3	Hs.105016	10	endoplasmic reticulum
224832_at	-0.318	7.087	-2.718	1.572e-02	0.199	-3.135	DUSP16	dual specificity phosphatase 16	12	-12520097	AB051487	80824	12p13	Hs.536535	12	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive	MAPK signaling pathway
209277_at	0.646	3.367	2.718	1.573e-02	0.199	-3.135	TFPI2	tissue factor pathway inhibitor 2	7	-93353680	AL574096	7980	7q22	Hs.438231	63	serine-type endopeptidase inhibitor activity extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix blood coagulation peptidase inhibitor activity
241389_at	0.187	6.607	2.718	1.574e-02	0.200	-3.136	CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	1	152806880	BE261002	1141	1q21.3	Hs.2306	59	conditioned taste aversion response to hypoxia nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport calcium ion transport smooth muscle contraction signal transduction synaptic transmission, cholinergic visual perception sensory perception of sound memory locomotory behavior visual learning external side of plasma membrane acetylcholine receptor activity integral to membrane sensory perception of pain vestibulocochlear nerve development optic nerve morphogenesis lateral geniculate nucleus development central nervous system projection neuron axonogenesis cell junction positive regulation of B cell proliferation positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion behavioral response to nicotine social behavior regulation of dopamine metabolic process B cell activation response to cocaine regulation of circadian sleep/wake cycle, REM sleep regulation of circadian sleep/wake cycle, non-REM sleep synapse postsynaptic membrane response to ethanol negative regulation of action potential regulation of dendrite morphogenesis cognition membrane depolarization regulation of synaptogenesis synaptic transmission involved in micturition
205051_s_at	0.533	4.706	2.717	1.575e-02	0.200	-3.137	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	4	55218851	NM_000222	3815	4q11-q12	Hs.479754	381	nucleotide binding myeloid progenitor cell differentiation lymphoid progenitor cell differentiation myeloid leukocyte differentiation receptor signaling protein tyrosine kinase activity receptor activity stem cell factor receptor activity protein binding ATP binding extracellular space nucleus nucleolus cytoplasm plasma membrane glycosphingolipid metabolic process signal transduction transmembrane receptor protein tyrosine kinase signaling pathway protein kinase cascade spermatogenesis spermatid development positive regulation of cell proliferation response to radiation external side of plasma membrane positive regulation of gene expression integral to membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway hemopoiesis germ cell programmed cell death negative regulation of programmed cell death positive regulation of MAP kinase activity regulation of pigmentation during development epithelial cell proliferation	Cytokine-cytokine receptor interaction Endocytosis Hematopoietic cell lineage Melanogenesis Pathways in cancer Acute myeloid leukemia
212992_at	0.298	3.712	2.717	1.576e-02	0.200	-3.137	AHNAK2	AHNAK nucleoprotein 2	14	-104474635	AI935123	113146	14q32.33	Hs.441783	3	protein binding nucleus cytoplasm keratinization
218221_at	-0.379	6.744	-2.717	1.576e-02	0.200	-3.137	ARNT	aryl hydrocarbon receptor nuclear translocator	1	-149048809	AL042842	405	1q21	Hs.632446	88	response to hypoxia positive regulation of endothelial cell proliferation RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus regulation of transcription, DNA-dependent signal transduction positive regulation vascular endothelial growth factor production aryl hydrocarbon receptor binding positive regulation of vascular endothelial growth factor receptor signaling pathway mRNA transcription from RNA polymerase II promoter positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of glycolysis positive regulation of hormone biosynthetic process protein heterodimerization activity	Pathways in cancer Renal cell carcinoma
224692_at	-0.549	6.812	-2.716	1.577e-02	0.200	-3.138	PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	1	-202639114	BF796046	84919	1q32.1	Hs.304376	6	protein phosphatase type 1 complex protein serine/threonine phosphatase activity regulation of translation response to oxidative stress ER overload response response to hydrogen peroxide
210632_s_at	-0.430	9.118	-2.716	1.578e-02	0.200	-3.138	SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	17	45598364	L35853	6442	17q21	Hs.463412	23	calcium ion binding protein binding cytoplasm cytoskeleton muscle contraction muscle organ development dystrophin-associated glycoprotein complex sarcoglycan complex integral to membrane sarcolemma membrane raft	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1557480_a_at	-0.552	9.889	-2.716	1.579e-02	0.200	-3.139	DYSFIP1	dysferlin interacting protein 1	17	-77384656	AI972007	116729	17q25.3	Hs.454720	5
218558_s_at	0.313	8.800	2.716	1.579e-02	0.200	-3.139	MRPL39	mitochondrial ribosomal protein L39	21	-25879838	NM_017446	54148	21q21.3	Hs.420696	10	nucleotide binding molecular_function mitochondrion mitochondrial ribosome ribosome biological_process
212337_at	-0.277	6.380	-2.715	1.581e-02	0.200	-3.140	TUG1	taurine upregulated 1 (non-protein coding)	22	29695633	AI687738	55000	22q12.2	Hs.554829	7
217675_at	0.252	3.419	2.715	1.581e-02	0.200	-3.140	ZBTB7C	zinc finger and BTB domain containing 7C	18	-43807742	BE734331	201501	18q21.1	Hs.515388	4	nucleic acid binding protein binding intracellular zinc ion binding metal ion binding
206306_at	1.215	8.987	2.715	1.581e-02	0.200	-3.140	RYR3	ryanodine receptor 3	15	31390468	NM_001036	6263	15q14-q15	Hs.709373	21	receptor activity ion channel activity ryanodine-sensitive calcium-release channel activity calcium ion binding ion transport calcium ion transport cellular calcium ion homeostasis striated muscle contraction calcium-release channel activity membrane integral to membrane junctional membrane complex sarcoplasmic reticulum membrane	Calcium signaling pathway Alzheimer's disease
1552678_a_at	-0.578	6.183	-2.715	1.582e-02	0.200	-3.140	USP28	ubiquitin specific peptidase 28	11	-113173806	NM_020886	57646	11q23	Hs.503891	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
202981_x_at	-0.311	8.135	-2.715	1.583e-02	0.200	-3.141	SIAH1	seven in absentia homolog 1 (Drosophila)	16	-46951954, -46951946	NM_003031	6477	16q12	Hs.295923	64	ubiquitin-protein ligase activity nucleus cytoplasm proteolysis ubiquitin-dependent protein catabolic process apoptosis cell cycle multicellular organismal development spermatogenesis nervous system development axon guidance protein C-terminus binding zinc ion binding anatomical structure morphogenesis protein ubiquitination ligase activity cell differentiation metal ion binding	p53 signaling pathway Ubiquitin mediated proteolysis Wnt signaling pathway
202565_s_at	-0.370	11.809	-2.715	1.583e-02	0.200	-3.141	SVIL	supervillin	10	-29786282, -29786282	NM_003174	6840	10p11.2	Hs.499209	23	podosome calcium ion binding nucleus cytoplasm plasma membrane cytoskeleton organization skeletal muscle tissue development cell projection costamere actin filament binding
203695_s_at	1.081	7.145	2.714	1.585e-02	0.200	-3.142	DFNA5	deafness, autosomal dominant 5	7	-24704498, -24704498	NM_004403	1687	7p15	Hs.520708	23	sensory perception of sound inner ear receptor cell differentiation
243225_at	0.275	4.023	2.714	1.585e-02	0.200	-3.142	LOC283481	hypothetical protein LOC283481	13		AI042341	283481	13q33.1	Hs.646604	2
1566832_at	0.190	2.437	2.714	1.586e-02	0.200	-3.143	TOP1P2	topoisomerase (DNA) I pseudogene 2	22	23490467	M55630	7152	22q11.2-q13.1 22q11.23	Hs.381281	1
204903_x_at	0.238	7.200	2.714	1.586e-02	0.200	-3.143	ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	2	242225699, 54821	AL080168	23192	2q37.3	Hs.283610	19	protein binding cytoplasm microtubule associated complex proteolysis autophagy peptidase activity cysteine-type peptidase activity protein transport modification-dependent protein catabolic process	Regulation of autophagy
203259_s_at	0.399	10.094	2.713	1.589e-02	0.200	-3.144	HDDC2	HD domain containing 2	6	-125638194	BC001671	51020	6q13-q24.3	Hs.32826	3	catalytic activity
231950_at	0.356	4.964	2.713	1.589e-02	0.200	-3.145	ZNF658	zinc finger protein 658	9	-40761401	AW874634	26149	9p13.1	Hs.522147	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202371_at	0.406	9.462	2.713	1.590e-02	0.201	-3.145	TCEAL4	transcription elongation factor A (SII)-like 4	X	102727074	NM_024863	79921	Xq22.2	Hs.194329	10	nucleus regulation of transcription
201046_s_at	-0.398	10.580	-2.712	1.590e-02	0.201	-3.145	RAD23A	RAD23 homolog A (S. cerevisiae)	19	12917653	NM_005053	5886	19p13.2	Hs.643267	40	damaged DNA binding single-stranded DNA binding protein binding nucleus nucleotide-excision repair response to DNA damage stimulus proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms	Nucleotide excision repair
222542_x_at	-0.681	6.701	-2.712	1.591e-02	0.201	-3.146	CABC1	chaperone, ABC1 activity of bc1 complex homolog (S. pombe)	1	225194560	BF724826	56997	1q42.13	Hs.118241	10	nucleotide binding ATP binding mitochondrion cell death kinase activity transferase activity
236154_at	-0.573	7.955	-2.712	1.593e-02	0.201	-3.147	QKI	quaking homolog, KH domain RNA binding (mouse)	6	163755664, 163755664	R41907	9444	6q26 6q26-q27	Hs.510324 Hs.593520	23	RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport
206407_s_at	0.457	4.935	2.712	1.593e-02	0.201	-3.147	CCL13	chemokine (C-C motif) ligand 13	17	29707583	NM_005408	6357	17q11.2	Hs.414629	30	signal transducer activity extracellular region extracellular space cellular calcium ion homeostasis chemotaxis inflammatory response immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
209652_s_at	0.301	5.062	2.711	1.594e-02	0.201	-3.147	PGF	placental growth factor	14	-74478290	BC001422	5228	14q24-q31	Hs.252820	79	angiogenesis extracellular region signal transduction cell-cell signaling multicellular organismal development growth factor activity heparin binding positive regulation of cell proliferation membrane cell differentiation	mTOR signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer
220547_s_at	-0.315	7.160	-2.711	1.594e-02	0.201	-3.148	FAM35A	family with sequence similarity 35, member A	10	88844932	NM_019054	54537	10q23.2	Hs.500419	6
239917_at	-0.601	5.620	-2.711	1.595e-02	0.201	-3.148	VPS8	vacuolar protein sorting 8 homolog (S. cerevisiae)	3	186012624	R07848	23355	3q27.2	Hs.269263	6	protein binding zinc ion binding metal ion binding
212454_x_at	-0.380	9.544	-2.711	1.595e-02	0.201	-3.148	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	AI762552	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
206055_s_at	-0.467	7.515	-2.711	1.596e-02	0.201	-3.148	SNRPA1	small nuclear ribonucleoprotein polypeptide A'	15	-99639237	NM_003090	6627	15q26.3	Hs.528763	22	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex U2 snRNP RNA splicing
238105_x_at	0.240	6.363	2.710	1.598e-02	0.201	-3.150	WNT7B	wingless-type MMTV integration site family, member 7B	22	-44694913	AW294903	7477	22q13	Hs.512714	10	signal transducer activity extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway cell-cell signaling multicellular organismal development organ morphogenesis positive regulation of osteoblast differentiation synapse organization	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
224824_at	0.529	7.843	2.709	1.600e-02	0.201	-3.151	FAM36A	family with sequence similarity 36, member A	1	243065261	AV694386	116228	1q44	Hs.715571	5	membrane integral to membrane
205996_s_at	-0.503	5.718	-2.709	1.601e-02	0.201	-3.151	AK2	adenylate kinase 2	1	-33251169, -33246172	NM_013411	204	1p34	Hs.470907	16	nucleotide binding adenylate kinase activity ATP binding mitochondrion mitochondrial intermembrane space mitochondrial intermembrane space nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity nucleoside kinase activity	Purine metabolism Metabolic pathways
1570279_at	-0.244	3.296	-2.709	1.601e-02	0.201	-3.151	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	9	-106583104	BC034824	19	9q31.1	Hs.719214	321	nucleotide binding ATP binding phospholipid binding phospholipid transporter activity membrane fraction integral to plasma membrane lipid metabolic process transport lysosome organization G-protein coupled receptor protein signaling pathway steroid metabolic process cholesterol metabolic process anion transmembrane transporter activity negative regulation of foam cell differentiation negative regulation of cholesterol storage cholesterol binding membrane endosome transport ATPase activity cholesterol transporter activity syntaxin-13 binding positive regulation of cAMP biosynthetic process small GTPase binding intracellular cholesterol transport Cdc42 protein signal transduction cholesterol efflux cholesterol efflux phospholipid efflux phospholipid efflux apolipoprotein A-I receptor activity high-density lipoprotein particle assembly cholesterol homeostasis reverse cholesterol transport membrane raft phagocytic vesicle interleukin-1 beta secretion phospholipid homeostasis platelet dense granule organization	ABC transporters
227339_at	-0.248	5.458	-2.709	1.602e-02	0.201	-3.152	RGMB	RGM domain family, member B	5	98132898	BE206621	285704	5q15	Hs.526902	5	ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane
226233_at	-0.474	8.307	-2.708	1.604e-02	0.201	-3.153	B3GALNT2	beta-1,3-N-acetylgalactosaminyltransferase 2	1	-233677155	BG112197	148789	1q42.3	Hs.716571	5	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups
227871_at	-0.376	6.962	-2.708	1.605e-02	0.201	-3.154	CHM	choroideremia (Rab escort protein 1)	X	-85110756, -85002840	AA878377	1121	Xq21.2	Hs.496449	44	blood vessel development Rab geranylgeranyltransferase activity GTPase activator activity protein binding Rab-protein geranylgeranyltransferase complex intracellular protein transport visual perception protein amino acid geranylgeranylation regulation of GTPase activity response to stimulus
203000_at	0.269	3.968	2.708	1.606e-02	0.201	-3.154	STMN2	stathmin-like 2	8	80685934	BF967657	11075	8q21.13	Hs.521651	23	protein binding membrane fraction soluble fraction cytoplasm intracellular signaling cascade membrane neuron differentiation axon growth cone cell projection perinuclear region of cytoplasm
205298_s_at	0.262	5.974	2.707	1.608e-02	0.202	-3.155	BTN2A2	butyrophilin, subfamily 2, member A2	6	26491332	W58757	10385	6p22.1	Hs.373938	8	membrane integral to membrane
222827_s_at	-1.063	11.393	-2.707	1.608e-02	0.202	-3.155	KBTBD10	kelch repeat and BTB (POZ) domain containing 10	2	170074457	AI126808	10324	2q31.1	Hs.50550	8	ruffle protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion striated muscle contraction modification-dependent protein catabolic process pseudopodium
201637_s_at	-0.300	10.494	-2.707	1.608e-02	0.202	-3.155	FXR1	fragile X mental retardation, autosomal homolog 1	3	182113145	NM_005087	8087	3q28	Hs.478407	30	RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation
226775_at	-0.487	6.845	-2.706	1.610e-02	0.202	-3.157	ENY2	enhancer of yellow 2 homolog (Drosophila)	8	110415811	N30904	56943	8q23.1	Hs.492555	5	SAGA complex nucleus transport chromatin modification histone deubiquitination ligand-dependent nuclear receptor transcription coactivator activity regulation of transcription positive regulation of transcription, DNA-dependent mRNA transport
226330_s_at	-0.370	6.292	-2.705	1.613e-02	0.202	-3.158	FAM48A	family with sequence similarity 48, member A	13	-36481450	BF739930	55578	13q13.3	Hs.435815	14	protein binding multicellular organismal development gastrulation
41329_at	-0.333	5.639	-2.705	1.613e-02	0.202	-3.158	SCYL3	SCY1-like 3 (S. cerevisiae)	1	-168088427	AI458463	57147	1q24.2	Hs.435560	11	protein kinase activity protein binding ATP binding cytoplasm Golgi apparatus protein amino acid phosphorylation cell migration lamellipodium
212632_at	-0.343	6.683	-2.705	1.614e-02	0.202	-3.159	STX7	syntaxin 7	6	-132820355	N32035	8417	6q23.1	Hs.593148 Hs.605992	31	SNAP receptor activity endosome Golgi apparatus intracellular protein transport post-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
227272_at	-0.292	7.763	-2.705	1.614e-02	0.202	-3.159	C15orf52	chromosome 15 open reading frame 52	15	-38410944	BE673226	388115	15q15.1	Hs.32433	3
213701_at	-0.400	6.912	-2.705	1.614e-02	0.202	-3.159	C12orf29	chromosome 12 open reading frame 29	12	86953398	AW299245	91298	12q21.32	Hs.591009	6
223263_s_at	-1.002	3.932	-2.705	1.615e-02	0.202	-3.159	FGFR1OP2	FGFR1 oncogene partner 2	12	26982582	AF161472	26127	12p11.23	Hs.591162	5	cytoplasm
213628_at	-0.448	6.920	-2.705	1.615e-02	0.202	-3.159	CLCC1	chloride channel CLIC-like 1	1	-109273652	AA883493	23155	1p13.3	Hs.658489	6	nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane
209868_s_at	0.330	7.283	2.705	1.615e-02	0.202	-3.159	RBMS1	RNA binding motif, single stranded interacting protein 1	2	-160836908	D28482	5937	2q24.2	Hs.470412	12	DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding cellular_component nucleus DNA replication RNA processing
240754_at	0.207	3.334	2.704	1.617e-02	0.202	-3.160	LOC284933	hypothetical protein LOC284933	22		AI382197	284933	22q13.32	Hs.159057	1
226103_at	-0.298	11.454	-2.704	1.617e-02	0.202	-3.160	NEXN	nexilin (F actin binding protein)	1	78126787	AF114264	91624	1p31.1	Hs.612385	6	cytoplasm cytoskeleton cell-substrate adherens junction cell junction regulation of cell migration actin filament binding regulation of cytoskeleton organization
1553185_at	-0.482	9.804	-2.704	1.618e-02	0.202	-3.161	RASEF	RAS and EF-hand domain containing	9	-84787136	NM_152573	158158	9q21.32	Hs.657750	3	nucleotide binding calcium ion binding GTP binding cytoplasm small GTPase mediated signal transduction protein transport perinuclear region of cytoplasm
204566_at	-0.403	5.770	-2.704	1.619e-02	0.202	-3.161	PPM1D	protein phosphatase 1D magnesium-dependent, delta isoform	17	56032335	NM_003620	8493	17q23.2	Hs.591184	37	magnesium ion binding protein serine/threonine phosphatase activity protein binding nucleus protein amino acid dephosphorylation cell cycle negative regulation of cell proliferation protein serine/threonine phosphatase complex response to radiation hydrolase activity manganese ion binding	p53 signaling pathway
210870_s_at	-0.532	7.276	-2.703	1.620e-02	0.202	-3.162	EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	6	-145988132	BC005286	7957	6q24	Hs.486696	37	protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm endoplasmic reticulum cytosol polysome plasma membrane carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity carbohydrate binding
1568594_s_at	0.311	5.062	2.703	1.621e-02	0.202	-3.162	TRIM52	tripartite motif-containing 52	5	-180615991	AW965171	84851	5q35.3	Hs.708154	3	protein binding intracellular zinc ion binding metal ion binding
1552632_a_at	0.290	2.847	2.703	1.621e-02	0.202	-3.163	ARSG	arylsulfatase G	17	63766917	BC012375	22901	17q24.2	Hs.437249	8	arylsulfatase activity arylsulfatase activity dolichol kinase activity calcium ion binding endoplasmic reticulum metabolic process hydrolase activity	Lysosome
203328_x_at	-0.296	6.198	-2.702	1.624e-02	0.203	-3.164	IDE	insulin-degrading enzyme	10	-94203579	NM_004969	3416	10q23-q25	Hs.500546	94	metalloendopeptidase activity signal transducer activity ATP binding extracellular space soluble fraction cytoplasm peroxisome proteolysis signal transduction sex differentiation peptidase activity zinc ion binding bradykinin catabolic process protein homodimerization activity metal ion binding beta-amyloid metabolic process	Alzheimer's disease
210517_s_at	0.520	6.839	2.702	1.624e-02	0.203	-3.164	AKAP12	A kinase (PRKA) anchor protein 12	6	151602826, 151688358	AB003476	9590	6q24-q25	Hs.371240	33	nucleus cytoplasm cytoskeleton plasma membrane cell cortex protein targeting signal transduction G-protein coupled receptor protein signaling pathway protein kinase A binding
216322_at	-0.211	1.929	-2.702	1.624e-02	0.203	-3.164	CD58	CD58 molecule	1	-116862845, -116858679	D28586	965	1p13	Hs.34341	38	protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane	Cell adhesion molecules (CAMs)
1558249_s_at	-0.450	5.476	-2.702	1.625e-02	0.203	-3.165	STX16	syntaxin 16	20	56659733, 56659733	BE878126	8675	20q13.32	Hs.307913	14	SNAP receptor activity cytoplasm microsome Golgi apparatus intracellular protein transport intra-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport SNARE complex retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
226969_at	-0.257	8.004	-2.701	1.626e-02	0.203	-3.165	MTR	5-methyltetrahydrofolate-homocysteine methyltransferase	1	235025203	AV706396	4548	1q43	Hs.498187	219	dihydropteroate synthase activity protein binding intracellular cytoplasm cytosol nervous system development methyltransferase activity zinc ion binding cellular amino acid biosynthetic process methionine synthase activity methionine synthase activity homocysteine S-methyltransferase activity methionine biosynthetic process folic acid and derivative biosynthetic process transferase activity cobalamin binding cellular metabolic process metal ion binding cobalt ion binding	Cysteine and methionine metabolism One carbon pool by folate Metabolic pathways
205614_x_at	0.241	6.119	2.701	1.628e-02	0.203	-3.166	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	3	-49696384	NM_020998	4485	3p21	Hs.349110 Hs.512587	31	catalytic activity serine-type endopeptidase activity calcium ion binding extracellular region proteolysis blood coagulation biological_process
224591_at	-0.309	9.480	-2.700	1.629e-02	0.203	-3.167	HP1BP3	heterochromatin protein 1, binding protein 3	1	-20941757	AK023129	50809	1p36.12	Hs.142442	3	nucleosome DNA binding nucleus chromosome nucleosome assembly
212314_at	0.309	5.226	2.700	1.629e-02	0.203	-3.167	KIAA0746	KIAA0746 protein	4	-25358146	AB018289	23231	4p15.2	Hs.479384	5	binding membrane integral to membrane
201744_s_at	1.053	8.136	2.700	1.630e-02	0.203	-3.168	LUM	lumican	12	-90021362	NM_002345	4060	12q21.3-q22	Hs.406475	41	extracellular matrix structural constituent collagen binding extracellular region proteinaceous extracellular matrix fibrillar collagen visual perception collagen fibril organization
227470_at	0.271	6.287	2.700	1.630e-02	0.203	-3.168	ZNF48	zinc finger protein 48	16	30314557	AI870369	197407	16p11.2	Hs.513501	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
206145_at	-0.226	2.310	-2.700	1.630e-02	0.203	-3.168	RHAG	Rh-associated glycoprotein	6	-49680848	NM_000324	6005	6p21.1-p11	Hs.120950	35	plasma membrane plasma membrane integral to plasma membrane transport cellular ion homeostasis ammonium transmembrane transporter activity ammonium transmembrane transporter activity carbon dioxide transport ammonium transport ammonium transport ankyrin binding ammonia transporter activity
225050_at	0.335	6.934	2.700	1.631e-02	0.203	-3.168	ZNF512	zinc finger protein 512	2	27659396	N22677	84450	2p23	Hs.529178	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203089_s_at	0.249	6.857	2.700	1.631e-02	0.203	-3.168	HTRA2	HtrA serine peptidase 2	2	74610039	NM_013247	27429	2p12	Hs.469045 Hs.716372	54	serine-type endopeptidase activity nucleus mitochondrion mitochondrial intermembrane space endoplasmic reticulum endoplasmic reticulum membrane proteolysis apoptosis response to stress mitochondrion organization adult walking behavior peptidase activity induction of apoptosis by intracellular signals membrane integral to membrane forebrain development regulation of multicellular organism growth neuron development unfolded protein binding	Parkinson's disease
200788_s_at	0.732	8.472	2.700	1.631e-02	0.203	-3.168	PEA15	phosphoprotein enriched in astrocytes 15	1	158441748	NM_003768	8682	1q21.1	Hs.517216	37	protein binding cytoplasm microtubule associated complex anti-apoptosis carbohydrate transport regulation of apoptosis negative regulation of glucose import
214032_at	0.237	4.464	2.699	1.633e-02	0.203	-3.169	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	2	97696462, 97717300	AI817942	7535	2q12	Hs.234569	168	nucleotide binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation immune response signal transduction protein kinase cascade transferase activity T cell receptor complex positive thymic T cell selection positive regulation of T cell differentiation	Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Primary immunodeficiency
204055_s_at	-0.832	6.349	-2.699	1.634e-02	0.203	-3.170	CTAGE5	CTAGE family, member 5	14	38804226, 38805252, 38806078	NM_005930	4253	14q13.3	Hs.509200 Hs.540038	13	protein binding enzyme activator activity
203356_at	-0.534	6.737	-2.699	1.635e-02	0.203	-3.170	CAPN7	calpain 7	3	15222736	BE349584	23473	3p24	Hs.631920	6	calcium-dependent cysteine-type endopeptidase activity intracellular nucleus proteolysis peptidase activity cysteine-type peptidase activity
217367_s_at	-0.254	5.554	-2.699	1.635e-02	0.203	-3.170	ZHX3	zinc fingers and homeoboxes 3	20	-39240502	AB007855	23051	20q12	Hs.380133	13	transcription factor activity protein binding intracellular nucleus cytoplasm zinc ion binding sequence-specific DNA binding negative regulation of transcription, DNA-dependent metal ion binding
225365_at	-0.323	5.561	-2.698	1.636e-02	0.203	-3.171	ZDHHC20	zinc finger, DHHC-type containing 20	13	-20848507	BG249221	253832	13q12.11	Hs.564611 Hs.693749	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
224857_s_at	-0.287	7.320	-2.698	1.636e-02	0.203	-3.171	POLR1D	polymerase (RNA) I polypeptide D, 16kDa	13	27094002, 27094028	BE378670	51082	13q12.2	Hs.507584	15	DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm transcription protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
230098_at	-0.367	7.466	-2.698	1.637e-02	0.203	-3.171	PHF20L1	PHD finger protein 20-like 1	8	133856785, 133856785, 133856785	AW612407	51105	8q24.22	Hs.304362	4	nucleic acid binding protein binding zinc ion binding metal ion binding
225718_at	-0.458	7.266	-2.698	1.637e-02	0.203	-3.171	KIAA1715	KIAA1715	2	-176498655	AL133768	80856	2q31	Hs.209561	7	protein binding multicellular organismal development membrane integral to membrane limb development
213261_at	0.358	5.451	2.698	1.638e-02	0.203	-3.172	LBA1	lupus brain antigen 1	3	-36843314	AA035414	9881	3p22.2	Hs.170999	3	binding
224731_at	-0.314	9.773	-2.697	1.640e-02	0.203	-3.173	HMGB1	high-mobility group box 1	13	-29930878	BF673940	3146	13q12	Hs.593339 Hs.596078 Hs.644368	157	condensed chromosome nucleus nucleolus DNA unwinding during replication DNA repair base-excision repair, DNA ligation DNA recombination chromatin organization regulation of transcription from RNA polymerase II promoter anti-apoptosis signal transduction transcription factor binding DNA bending activity negative regulation of transcriptional preinitiation complex assembly	Base excision repair
229394_s_at	-0.420	8.971	-2.697	1.640e-02	0.203	-3.173	GRLF1	glucocorticoid receptor DNA binding factor 1	19	52113772	AI275597	2909	19q13.3	Hs.509447	26	DNA binding transcription corepressor activity GTPase activator activity intracellular nucleus cytoplasm signal transduction negative regulation of transcription	Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
227407_at	-0.432	9.295	-2.697	1.640e-02	0.203	-3.173	TAPT1	transmembrane anterior posterior transformation 1	4	-15771225	AI341541	202018	4p15.32	Hs.479223	5	receptor activity multicellular organismal development membrane integral to membrane
239011_at	0.351	4.625	2.697	1.641e-02	0.203	-3.174	PRKCE	protein kinase C, epsilon	2	45732546	AI247134	5581	2p21	Hs.580351	178	nucleotide binding protein kinase C activity signal transducer activity ATP binding membrane fraction protein amino acid phosphorylation induction of apoptosis intracellular signaling cascade zinc ion binding transferase activity enzyme binding diacylglycerol binding metal ion binding	Vascular smooth muscle contraction Tight junction Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Type II diabetes mellitus
244871_s_at	-0.276	5.364	-2.697	1.641e-02	0.203	-3.174	USP32	ubiquitin specific peptidase 32	17	-55609472	AW268357	84669	17q23.1-q23.2	Hs.132868	6	ubiquitin thiolesterase activity calcium ion binding ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity membrane
201153_s_at	-0.408	10.686	-2.697	1.642e-02	0.203	-3.174	MBNL1	muscleblind-like (Drosophila)	3	153468518, 153499883	NM_021038	4154	3q25	Hs.478000 Hs.558914	21	in utero embryonic development double-stranded RNA binding nucleus cytoplasm nervous system development muscle organ development zinc ion binding embryonic limb morphogenesis myoblast differentiation metal ion binding
1557430_at	0.373	3.019	2.696	1.642e-02	0.203	-3.174	LOC147670	hypothetical protein LOC147670	19		BG910569	147670	19q13.43	Hs.336588	1
225098_at	0.276	7.617	2.696	1.642e-02	0.203	-3.174	ABI2	abl-interactor 2	2	203901247	BF245400	10152	2q33	Hs.471156	22	DNA binding SH3/SH2 adaptor activity cytoplasm cytoplasm cytosol cytoskeleton cell motion cytoskeleton organization cytoskeletal adaptor activity actin polymerization or depolymerization cell migration SH3 domain binding peptidyl-tyrosine phosphorylation kinase binding lamellipodium filopodium	Regulation of actin cytoskeleton
203227_s_at	-0.342	7.828	-2.696	1.643e-02	0.203	-3.175	TSPAN31	tetraspanin 31	12	56425050	NM_005981	6302	12q13.3	Hs.632708	12	membrane fraction integral to plasma membrane positive regulation of cell proliferation membrane
209259_s_at	-0.455	7.092	-2.696	1.643e-02	0.203	-3.175	SMC3	structural maintenance of chromosomes 3	10	112317438	AF020043	9126	10q25	Hs.24485	32	nucleotide binding chromatin lateral element spindle pole microtubule motor activity ATP binding basement membrane nucleus chromosome cytoplasm DNA repair response to DNA damage stimulus cell cycle mitotic spindle organization sister chromatid cohesion mitosis meiosis signal transduction cohesin complex DNA mediated transformation nuclear matrix dynein binding protein heterodimerization activity cell division	Cell cycle
209895_at	-0.845	5.951	-2.696	1.644e-02	0.203	-3.175	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12	111340918	AF119855	5781	12q24	Hs.506852 Hs.646231	326	non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity	Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia
212135_s_at	0.422	6.452	2.696	1.644e-02	0.203	-3.175	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	1	201862550	AW517686	493	1q32.1	Hs.343522	49	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	Calcium signaling pathway
214102_at	-0.420	5.927	-2.696	1.644e-02	0.203	-3.176	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	4	-35744016	AK023737	116984	4p14	Hs.479451	9	phosphatidylinositol-3,4,5-trisphosphate binding intracellular cytoplasm signal transduction ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding	Endocytosis
218532_s_at	-0.579	10.071	-2.696	1.645e-02	0.203	-3.176	FAM134B	family with sequence similarity 134, member B	5	-16526146, -16526146	NM_019000	54463	5p15.1	Hs.481704	4	membrane integral to membrane
223196_s_at	0.527	5.855	2.696	1.645e-02	0.203	-3.176	SESN2	sestrin 2	1	28458592	AL136551	83667	1p35.3	Hs.469543	8	nucleus cytoplasm cell cycle arrest	p53 signaling pathway
212887_at	-0.403	8.919	-2.696	1.645e-02	0.203	-3.176	SEC23A	Sec23 homolog A (S. cerevisiae)	14	-38570873	AI753659	10484	14q21.1	Hs.272927	18	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport zinc ion binding membrane membrane organization vesicle-mediated transport COPII vesicle coat perinuclear region of cytoplasm
203622_s_at	-0.449	7.314	-2.695	1.648e-02	0.203	-3.177	PNO1	partner of NOB1 homolog (S. cerevisiae)	2	68238508	NM_020143	56902	2p14	Hs.262858	8	RNA binding nucleus nucleolus
218191_s_at	-0.466	8.686	-2.695	1.649e-02	0.203	-3.178	LMBRD1	LMBR1 domain containing 1	6	-70442469	NM_018368	55788	6q13	Hs.271643	9	lysosome transport membrane integral to membrane cobalamin binding interspecies interaction between organisms cobalt ion binding
218024_at	0.404	10.668	2.694	1.649e-02	0.203	-3.178	BRP44L	brain protein 44-like	6	-166698399	NM_016098	51660	6q27	Hs.172755	7	molecular_function cellular_component mitochondrion biological_process
206174_s_at	-0.392	7.891	-2.694	1.649e-02	0.203	-3.178	PPP6C	protein phosphatase 6, catalytic subunit	9	-126948672	NM_002721	5537	9q33.3	Hs.715605	16	G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding
1558118_at	0.342	4.994	2.694	1.652e-02	0.203	-3.180	DGCR5	DiGeorge syndrome critical region gene 5 (non-protein coding)	22	17338026	BU584635	26220	22q11	Hs.646438	2
1568865_at	-0.363	4.725	-2.693	1.652e-02	0.203	-3.180	FNTB	farnesyltransferase, CAAX box, beta	14	64523259	BC035148	2342	14q23-q24	Hs.632345	26	farnesyltranstransferase activity protein farnesyltransferase activity protein binding zinc ion binding negative regulation of cell proliferation transferase activity protein amino acid farnesylation wound healing metal ion binding positive regulation of fibroblast proliferation
202177_at	0.365	7.269	2.693	1.654e-02	0.204	-3.181	GAS6	growth arrest-specific 6	13	113546896, 113574925, 113577228	NM_000820	2621	13q34	Hs.646346	45	receptor binding calcium ion binding extracellular region signal transduction cell proliferation organ regeneration regulation of growth
229476_s_at	0.759	6.260	2.692	1.656e-02	0.204	-3.182	THRSP	thyroid hormone responsive (SPOT14 homolog, rat)	11	77452554	AW272342	7069	11q13.5	Hs.591969	12	protein binding nucleus lipid metabolic process
212458_at	0.425	5.786	2.692	1.656e-02	0.204	-3.182	SPRED2	sprouty-related, EVH1 domain containing 2	2	-65391488, -65391488	H97931	200734	2p14	Hs.59332	19	inactivation of MAPK activity stem cell factor receptor binding protein binding cytoplasm plasma membrane multicellular organismal development regulation of signal transduction cytoplasmic vesicle	Jak-STAT signaling pathway
203281_s_at	0.237	5.558	2.692	1.659e-02	0.204	-3.183	UBA7	ubiquitin-like modifier activating enzyme 7	3	-49817641	NM_003335	7318	3p21	Hs.16695	14	nucleotide binding ATP binding protein modification process metabolic process ligase activity ISG15 activating enzyme activity modification-dependent protein catabolic process ISG15-protein conjugation	Ubiquitin mediated proteolysis Parkinson's disease
204217_s_at	-0.459	8.193	-2.691	1.662e-02	0.204	-3.185	RTN2	reticulon 2	19	-50680389, -50680389, -50680389	NM_005619	6253	19q13.32	Hs.47517	10	signal transducer activity endoplasmic reticulum signal transduction membrane integral to membrane integral to endoplasmic reticulum membrane
202396_at	-0.403	8.091	-2.690	1.663e-02	0.204	-3.186	TCERG1	transcription elongation regulator 1	5	145807065	NM_006706	10915	5q31	Hs.443465	23	RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus transcription from RNA polymerase II promoter regulation of transcription
223859_at	0.501	3.834	2.690	1.663e-02	0.204	-3.186	EPB41L4B	erythrocyte membrane protein band 4.1 like 4B	9	-111041832, -110974074	AF153416	54566	9q31-q32	Hs.591901	4	structural constituent of cytoskeleton binding cytoplasm cytoskeleton cytoskeletal protein binding extrinsic to membrane
225044_at	0.304	7.299	2.690	1.663e-02	0.204	-3.186	NT5C3L	5'-nucleotidase, cytosolic III-like	17	-37234948	AL526783	115024	17q21.2	Hs.237536	1	nucleotide binding magnesium ion binding cytoplasm 5'-nucleotidase activity nucleotide metabolic process transferase activity hydrolase activity
208921_s_at	0.285	8.173	2.690	1.664e-02	0.204	-3.186	SRI	sorcin	7	-87672367, -87672367	L12387	6717	7q21.1	Hs.489040	28	regulation of action potential receptor binding calcium channel regulator activity calcium ion binding cytoplasm transport intracellular sequestering of iron ion regulation of striated muscle contraction signal transduction heart development muscle organ development regulation of heart contraction
232180_at	-0.868	6.639	-2.690	1.664e-02	0.204	-3.186	UGP2	UDP-glucose pyrophosphorylase 2	2	63921601, 63922517	U00954	7360	2p14-p13	Hs.516217	9	UTP:glucose-1-phosphate uridylyltransferase activity UTP:glucose-1-phosphate uridylyltransferase activity protein binding cytoplasm cytosol UDP-glucose metabolic process metabolic process phosphorylation transferase activity nucleotidyltransferase activity	Pentose and glucuronate interconversions Galactose metabolism Starch and sucrose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
225200_at	-0.725	7.822	-2.690	1.664e-02	0.204	-3.186	DPH3	DPH3, KTI11 homolog (S. cerevisiae)	3	-16273572	AU151106	285381	3p25.1	Hs.388087	8	protein binding nucleus cytoplasm zinc ion binding peptidyl-diphthamide biosynthetic process from peptidyl-histidine metal ion binding negative regulation of protein secretion positive regulation of binding
209577_at	0.211	6.605	2.690	1.664e-02	0.204	-3.186	PCYT2	phosphate cytidylyltransferase 2, ethanolamine	17	-77455383, -2421678	BC000351	5833	17q25.3	Hs.645248	8	ethanolamine-phosphate cytidylyltransferase activity cellular_component phospholipid biosynthetic process biosynthetic process transferase activity nucleotidyltransferase activity	Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways
205656_at	0.277	5.810	2.690	1.665e-02	0.204	-3.187	PCDH17	protocadherin 17	13	57103789	NM_014459	27253	13q21.1	Hs.106511	11	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
216760_at	0.359	4.730	2.689	1.666e-02	0.204	-3.188	HRASLS2	HRAS-like suppressor 2	11	-63076817	AK025029	54979	11q12.3	Hs.272805	2
231411_at	0.342	6.308	2.689	1.666e-02	0.204	-3.188	LHFP	lipoma HMGIC fusion partner	13	-38815028	BE674089	10186	13q12	Hs.507798	8	DNA binding membrane integral to membrane
212523_s_at	0.266	3.874	2.689	1.667e-02	0.204	-3.188	KIAA0146	KIAA0146	8	48336094	D63480	23514	8q11.21	Hs.381058	6
201829_at	-0.346	6.941	-2.689	1.668e-02	0.204	-3.189	NET1	neuroepithelial cell transforming 1	10	5444517, 5478545	AW263232	10276	10p15	Hs.25155	19	regulation of cell growth guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity cellular_component intracellular nucleus cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction
202218_s_at	0.325	6.107	2.688	1.669e-02	0.204	-3.189	FADS2	fatty acid desaturase 2	11	61352288	NM_004265	9415	11q12-q13.1	Hs.502745	29	stearoyl-CoA 9-desaturase activity membrane fraction endoplasmic reticulum integral to plasma membrane unsaturated fatty acid biosynthetic process transport membrane oxidoreductase activity heme binding electron transport chain	alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids PPAR signaling pathway
230427_s_at	-0.521	4.173	-2.688	1.669e-02	0.204	-3.189	BAG5	BCL2-associated athanogene 5	14	-103092641, -103092641, -103092641	AW673909	9529	14q32.33	Hs.5443	10	protein binding protein folding apoptosis
226506_at	0.254	6.669	2.688	1.670e-02	0.204	-3.190	THSD4	thrombospondin, type I, domain containing 4	15	69220841	AI742570	79875	15q23	Hs.387057	6	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix peptidase activity
216137_s_at	0.215	5.817	2.688	1.670e-02	0.205	-3.190	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	16	1696221	AL031718	23162	16p13.3	Hs.207763	23	Golgi membrane MAP-kinase scaffold activity cytoplasm vesicle-mediated transport kinesin binding protein kinase binding regulation of JNK cascade	MAPK signaling pathway
224883_at	-0.508	6.155	-2.688	1.671e-02	0.205	-3.190	PLDN	pallidin homolog (mouse)	15	43666708	AI344311	26258	15q21.1	Hs.719102	17	cellular_component cytoplasm endosome membrane fusion blood coagulation membrane synaptic vesicle docking during exocytosis melanocyte differentiation syntaxin-13 binding positive regulation of natural killer cell activation secretion of lysosomal enzymes identical protein binding pigmentation
200814_at	0.566	9.031	2.687	1.672e-02	0.205	-3.191	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	14	23675217	NM_006263	5720	14q11.2	Hs.75348	56	proteasome complex cytoplasm cytosol proteasome activator complex proteasome activator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome Antigen processing and presentation
203946_s_at	2.498	5.799	2.687	1.673e-02	0.205	-3.191	ARG2	arginase, type II	14	67156331	U75667	384	14q24.1-q24.3	Hs.708024	21	urea cycle arginase activity protein binding mitochondrion arginine metabolic process striated muscle contraction hydrolase activity manganese ion binding regulation of nitric oxide biosynthetic process metal ion binding nitric-oxide synthase binding negative regulation of nitric-oxide synthase activity	Arginine and proline metabolism Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
1560609_at	-0.286	3.329	-2.686	1.676e-02	0.205	-3.193	CRYZL1	crystallin, zeta (quinone reductase)-like 1	21	-33883517	BC022827	9946	21q21.3	Hs.352671	9	NADPH:quinone reductase activity binding cytosol zinc ion binding oxidoreductase activity quinone cofactor metabolic process NADP or NADPH binding oxidation reduction
209742_s_at	0.213	13.751	2.686	1.676e-02	0.205	-3.193	MYL2	myosin, light chain 2, regulatory, cardiac, slow	12	-109833006	AF020768	4633	12q24.11	Hs.75535	34	motor activity actin monomer binding calcium ion binding protein binding regulation of striated muscle contraction structural constituent of muscle myosin complex sarcomere negative regulation of cell growth myosin heavy chain binding cardiac myofibril assembly ventricular cardiac muscle morphogenesis heart contraction	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM)
202878_s_at	0.489	8.426	2.686	1.676e-02	0.205	-3.193	CD93	CD93 molecule	20	-23007992	NM_012072	22918	20p11.21	Hs.97199	35	complement component C1q binding receptor activity calcium ion binding protein binding sugar binding plasma membrane phagocytosis cell surface integral to membrane cytoplasmic membrane-bounded vesicle cell-cell adhesion macrophage activation interspecies interaction between organisms
211096_at	0.303	6.027	2.686	1.676e-02	0.205	-3.193	PBX2	pre-B-cell leukemia homeobox 2	6	-32260487, -3559697, -3367476	BC003111	5089	6p21.3	Hs.509545 Hs.718462	18	chromatin binding transcription factor activity protein binding nucleus transcription factor complex regulation of transcription, DNA-dependent proximal/distal pattern formation embryonic limb morphogenesis sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter
208832_at	-0.254	6.761	-2.686	1.678e-02	0.205	-3.194	ATXN10	ataxin 10	22	44446350	AW241832	25814	22q13.31	Hs.475125	25	protein binding cytoplasm nervous system development cell death dendrite cell soma perinuclear region of cytoplasm
1566916_at	0.224	2.978	2.685	1.680e-02	0.205	-3.195	HPYR1	Helicobacter pylori responsive 1 (non-protein coding)	8	-133641926	AF200341	93668	8q24.22	Hs.545218	1
230790_x_at	-0.461	6.398	-2.685	1.681e-02	0.205	-3.196	FOXN3	forkhead box N3	14	-88692268, -88692268	AI589978	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
218870_at	0.261	5.130	2.685	1.681e-02	0.205	-3.196	ARHGAP15	Rho GTPase activating protein 15	2	143603368	NM_018460	55843	2q22.2-q22.3	Hs.171011	8	GTPase activator activity intracellular cytoplasm signal transduction membrane
222434_at	-0.517	5.829	-2.684	1.682e-02	0.205	-3.196	ENAH	enabled homolog (Drosophila)	1	-223741156	AI963713	55740	1q42.12	Hs.497893	37	actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding	Regulation of actin cytoskeleton
218298_s_at	0.322	8.438	2.684	1.683e-02	0.205	-3.196	C14orf159	chromosome 14 open reading frame 159	14	90650109, 90650731	NM_024952	80017	14q32.11	Hs.309849	12	mitochondrion
231157_at	-0.378	5.922	-2.684	1.684e-02	0.205	-3.197	TTLL11	tubulin tyrosine ligase-like family, member 11	9	-123791010, -123624025	BE856668	158135	9q33.2	Hs.640663 Hs.644262	5	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process ligase activity
213419_at	-1.140	5.224	-2.684	1.684e-02	0.205	-3.197	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	4	-40506801	U62325	323	4p14-p13	Hs.479602	12	beta-amyloid binding nucleus cell cycle arrest intracellular signaling cascade transcription factor binding membrane lamellipodium negative regulation of cell growth growth cone synapse regulation of transcription negative regulation of S phase of mitotic cell cycle
218471_s_at	0.253	6.786	2.684	1.685e-02	0.205	-3.198	BBS1	Bardet-Biedl syndrome 1	11	66034694	NM_024649	582	11q13.1	Hs.502915	22	microtubule cytoskeleton organization retina homeostasis protein binding cytoplasm plasma membrane sensory perception of smell photoreceptor cell morphogenesis flagellum assembly fertilization dendrite development striatum development hippocampus development cerebral cortex development adult behavior motile secondary cilium BBSome sensory cilium assembly multicellular organism growth olfactory behavior hormone metabolic process cellular lipid metabolic process fat cell differentiation photoreceptor cell maintenance brain morphogenesis response to stimulus cilium membrane cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility
225185_at	-0.395	7.857	-2.684	1.686e-02	0.205	-3.198	MRAS	muscle RAS oncogene homolog	3	139549314, 139550197	BF343625	22808	3q22.3	Hs.527021	18	nucleotide binding GTPase activity GTP binding intracellular plasma membrane Ras protein signal transduction multicellular organismal development muscle organ development actin cytoskeleton organization GTP-dependent protein binding	MAPK signaling pathway Tight junction Regulation of actin cytoskeleton
243894_at	-0.208	2.730	-2.683	1.686e-02	0.205	-3.198	SLC41A2	solute carrier family 41, member 2	12	-103721404	BG169689	84102	12q23.3	Hs.577463	6	magnesium ion binding plasma membrane cation transport cation transmembrane transporter activity integral to membrane
219607_s_at	0.961	3.226	2.683	1.686e-02	0.205	-3.198	MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	11	59804714, 59806661	NM_024021	51338	11q12	Hs.325960	6	receptor activity signal transduction membrane integral to membrane
221887_s_at	0.277	5.913	2.683	1.686e-02	0.205	-3.198	DFNB31	deafness, autosomal recessive 31	9	-116204180, -116204180	BE045998	25861	9q32-q34	Hs.93836	13	retina homeostasis protein binding cytoplasm visual perception sensory perception of sound growth cone stereocilium cell projection response to stimulus inner ear receptor stereocilium organization
222624_s_at	-0.480	5.890	-2.683	1.687e-02	0.205	-3.199	ZNF639	zinc finger protein 639	3	180524244	AA224199	51193	3q26.33	Hs.632578	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203048_s_at	-0.404	7.543	-2.683	1.688e-02	0.205	-3.199	TTC37	tetratricopeptide repeat domain 37	5	-94825877	BE566023	9652	5q15	Hs.482868	4	binding	RNA degradation
202317_s_at	-0.337	7.911	-2.682	1.690e-02	0.206	-3.200	UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	1	10015602	NM_006048	10277	1p36.3	Hs.632370	17	ubiquitin ligase complex cytoplasm apoptosis response to UV enzyme binding ubiquitin-ubiquitin ligase activity protein ubiquitination during ubiquitin-dependent protein catabolic process	Ubiquitin mediated proteolysis
222661_at	-0.314	7.006	-2.682	1.690e-02	0.206	-3.200	AGGF1	angiogenic factor with G patch and FHA domains 1	5	76361987	AA528017	55109	5q13.3	Hs.634849	12	vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm
1555421_at	0.215	2.075	2.682	1.690e-02	0.206	-3.200	AP1S3	adaptor-related protein complex 1, sigma 3 subunit	2	-224328290	BC009606	130340	2q36.1	Hs.632555	13	protein binding Golgi apparatus cytosol coated pit intracellular protein transport endocytosis protein transporter activity membrane membrane coat clathrin coat of trans-Golgi network vesicle clathrin adaptor complex cytoplasmic vesicle	Lysosome
211151_x_at	0.241	4.464	2.682	1.691e-02	0.206	-3.201	GH1	growth hormone 1	17	-59348294	AF185611	2688	17q24.2	Hs.655229	227	positive regulation of receptor internalization growth hormone receptor binding prolactin receptor binding protein binding extracellular region extracellular space growth factor activity positive regulation of activation of JAK2 kinase activity positive regulation of phosphoinositide 3-kinase cascade glucose transport response to estradiol stimulus positive regulation of multicellular organism growth positive regulation of multicellular organism growth positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein positive regulation of MAP kinase activity positive regulation of insulin-like growth factor receptor signaling pathway positive regulation of JAK-STAT cascade positive regulation of peptidyl-tyrosine phosphorylation growth hormone receptor signaling pathway growth hormone activity	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Jak-STAT signaling pathway
201375_s_at	-0.284	10.090	-2.682	1.691e-02	0.206	-3.201	PPP2CB	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	8	-30762667	NM_004156	5516	8p12	Hs.491440	40	protein phosphatase type 2A complex chromosome, centromeric region protein serine/threonine phosphatase activity iron ion binding protein binding nucleus cytoplasm spindle protein amino acid dephosphorylation regulation of gene expression hydrolase activity manganese ion binding response to hydrogen peroxide negative regulation of apoptosis proteasomal ubiquitin-dependent protein catabolic process response to antibiotic metal ion binding	Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression
213068_at	0.766	7.169	2.682	1.692e-02	0.206	-3.201	DPT	dermatopontin	1	-166931329	AI146848	1805	1q12-q23	Hs.80552	13	protein binding extracellular region proteinaceous extracellular matrix cell adhesion negative regulation of cell proliferation collagen fibril organization
203396_at	-0.235	9.065	-2.681	1.693e-02	0.206	-3.202	PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	15	76619801	NM_002789	5685	15q25.1	Hs.251531	47	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process identical protein binding negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
201215_at	0.519	8.721	2.681	1.695e-02	0.206	-3.203	PLS3	plastin 3 (T isoform)	X	114701461, 114734075	NM_005032	5358	Xq23	Hs.496622	21	actin binding calcium ion binding protein binding cytoplasm actin filament organization
210740_s_at	-0.261	7.516	-2.681	1.696e-02	0.206	-3.203	ITPK1	inositol 1,3,4-triphosphate 5/6 kinase	14	-92475821, -92473011	AF279372	3705	14q31	Hs.308122	12	nucleotide binding magnesium ion binding ATP binding intracellular signal transduction kinase activity transferase activity hydrolase activity isomerase activity inositol trisphosphate metabolic process inositol-1,3,4-trisphosphate 5/6-kinase activity inositol tetrakisphosphate 1-kinase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
232146_at	0.383	9.123	2.680	1.696e-02	0.206	-3.204	NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	4	-140430540	AK023115	4717	4q28.2-q31.1	Hs.84549	8	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
225216_at	-0.326	7.241	-2.680	1.698e-02	0.206	-3.205	CXorf39	chromosome X open reading frame 39	X	103297956	AI590719	139231	Xq22.2	Hs.496535 Hs.592223	5
221383_at	0.287	5.422	2.680	1.699e-02	0.206	-3.205	NMUR1	neuromedin U receptor 1	2	-232096114	NM_006056	10316	2q37.1	Hs.471619	10	neuromedin U receptor activity neuromedin U receptor activity receptor activity G-protein coupled receptor activity membrane fraction plasma membrane integral to plasma membrane calcium ion transport calcium ion transport chloride transport smooth muscle contraction smooth muscle contraction signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger neuropeptide signaling pathway transmission of nerve impulse transmission of nerve impulse calcium-mediated signaling inositol phosphate-mediated signaling	Neuroactive ligand-receptor interaction
230404_at	0.243	4.668	2.679	1.700e-02	0.206	-3.206	FLJ44606	glutaredoxin-like protein YDR286C homolog	5		AI418538	401207	5q23.2	Hs.49573	1	transport electron transport chain
212056_at	-0.337	6.990	-2.679	1.701e-02	0.206	-3.206	KIAA0182	KIAA0182	16	84202529, 84204424	D80004	23199	16q24.1	Hs.461647	11	protein binding
228988_at	0.993	4.851	2.679	1.701e-02	0.206	-3.206	ZNF711	zinc finger protein 711	X	84385652	AU157017	7552	Xq21.1-q21.2	Hs.326801	7	DNA binding intracellular nucleus zinc ion binding transcription regulator activity regulation of transcription metal ion binding
223037_at	0.402	7.586	2.679	1.702e-02	0.206	-3.207	PDZD11	PDZ domain containing 11	X	-69422935	AF151061	51248	Xq13.1	Hs.11042	12	protein binding extracellular region
203526_s_at	-0.577	4.157	-2.678	1.703e-02	0.206	-3.207	APC	adenomatous polyposis coli	5	112071116, 112101454	M74088	324	5q21-q22	Hs.158932	386	cytokinesis after mitosis kinetochore kidney development hair follicle development nucleus cytoplasm centrosome cytosol cytoplasmic microtubule protein complex assembly response to DNA damage stimulus negative regulation of microtubule depolymerization cell cycle arrest mitotic metaphase/anaphase transition mitotic cell cycle spindle assembly checkpoint axonogenesis beta-catenin binding microtubule binding axis specification anterior/posterior pattern formation dorsal/ventral pattern formation proximal/distal pattern formation lateral plasma membrane protein kinase regulator activity protein kinase binding negative regulation of Wnt receptor signaling pathway positive regulation of cell migration growth cone positive regulation of epithelial cell differentiation beta-catenin destruction complex positive regulation of microtubule polymerization cell projection membrane positive regulation of pseudopodium assembly T cell differentiation in the thymus axon part Axin-APC-beta-catenin-GSK3B complex somatic stem cell maintenance negative regulation of odontogenesis cell projection positive regulation of apoptosis negative regulation of apoptosis negative regulation of MAPKKK cascade skin development regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process negative regulation of cyclin-dependent protein kinase activity positive regulation of cell adhesion muscle maintenance thymus development negative regulation of epithelial cell proliferation regulation of nitrogen compound metabolic process chromosome organization regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye Wnt receptor signaling pathway through beta-catenin Wnt receptor signaling pathway through beta-catenin	Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma
227733_at	0.356	3.526	2.678	1.704e-02	0.206	-3.208	TMEM63C	transmembrane protein 63C	14	76717854	AA928939	57156	14q24.3	Hs.22452	3	membrane integral to membrane
204986_s_at	0.294	5.359	2.677	1.708e-02	0.207	-3.210	TAOK2	TAO kinase 2	16	29892722, 29892722	NM_016151	9344	16p11.2	Hs.291623	16	nucleotide binding activation of MAPKK activity magnesium ion binding regulation of cell growth protein serine/threonine kinase activity ATP binding protein targeting to membrane apoptosis response to stress regulation of cell shape membrane integral to membrane cytoplasmic membrane-bounded vesicle cell migration transferase activity actin cytoskeleton organization positive regulation of JNK cascade focal adhesion formation	MAPK signaling pathway
218847_at	-0.314	5.262	-2.677	1.709e-02	0.207	-3.211	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	3	-186844220	NM_006548	10644	3q27.2	Hs.35354	55	nucleotide binding RNA binding protein binding nucleus cytoplasm biological_process anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process cytoskeletal part translation regulator activity mRNA 5'-UTR binding
230679_at	-0.329	3.507	-2.676	1.710e-02	0.207	-3.211	DCAF10	DDB1 and CUL4 associated factor 10	9	37790789	AA976778	79269	9p13.2	Hs.118394	2
229030_at	0.297	3.947	2.676	1.710e-02	0.207	-3.211	CAPN8	calpain 8	1	-221781594	AW242997	388743	1q41	Hs.291487 Hs.670199	9	calcium-dependent cysteine-type endopeptidase activity calcium ion binding intracellular cytoplasm Golgi apparatus proteolysis peptidase activity
237033_at	-0.272	4.818	-2.676	1.712e-02	0.207	-3.212	FAM159A	family with sequence similarity 159, member A	1	52871653	AI202832	348378	1p32.3	Hs.424589	2	membrane integral to membrane
203315_at	-0.281	8.167	-2.676	1.712e-02	0.207	-3.212	NCK2	NCK adaptor protein 2	2	105727785, 105834736	BC000103	8440	2q12	Hs.529244 Hs.707062	34	protein binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal transduction signal complex assembly epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor activity cytoskeletal adaptor activity negative regulation of cell proliferation vesicle membrane cell migration lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation	ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC
202009_at	-0.264	8.592	-2.676	1.713e-02	0.207	-3.212	TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	3	-52237665	NM_007284	11344	3p21.1	Hs.436439	9	actin binding protein binding ATP binding intracellular cytoplasm cytoskeleton perinuclear region of cytoplasm
1563607_x_at	-0.205	4.532	-2.675	1.713e-02	0.207	-3.213	hCG_2045089	hypothetical LOC286359	9	-99192941	AL833510	286359	9q22.33	Hs.132262	2
201539_s_at	-0.834	11.817	-2.675	1.713e-02	0.207	-3.213	FHL1	four and a half LIM domains 1	X	135056526, 135057224, 135058402, 135079120, 135079731, 135106578, 135106720	U29538	2273	Xq26	Hs.435369	38	molecular_function cellular_component nucleus cytoplasm cytosol multicellular organismal development muscle organ development zinc ion binding organ morphogenesis cell growth cell differentiation metal ion binding
204396_s_at	0.237	6.649	2.675	1.714e-02	0.207	-3.213	GRK5	G protein-coupled receptor kinase 5	10	120957186	NM_005308	2869	10q24-qter	Hs.524625	38	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity protein kinase C binding protein binding ATP binding phospholipid binding soluble fraction cytoplasm plasma membrane protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger tachykinin receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway transferase activity	Chemokine signaling pathway Endocytosis
241646_s_at	0.240	5.219	2.675	1.715e-02	0.207	-3.213	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	AW470942	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
204336_s_at	0.319	5.732	2.675	1.715e-02	0.207	-3.214	RGS19	regulator of G-protein signaling 19	20	-62174978, -62174978	NM_005873	10287	20q13.33	Hs.422336	25	signal transducer activity protein binding membrane fraction Golgi apparatus heterotrimeric G-protein complex autophagy G-protein coupled receptor protein signaling pathway small GTPase mediated signal transduction negative regulation of signal transduction membrane
202309_at	0.286	8.723	2.675	1.715e-02	0.207	-3.214	MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	14	63924511	NM_005956	4522	14q24	Hs.652308	68	histidine biosynthetic process nucleotide binding formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity protein binding ATP binding cytoplasm mitochondrion purine nucleotide biosynthetic process histidine catabolic process one-carbon metabolic process cellular amino acid biosynthetic process methionine biosynthetic process folic acid and derivative biosynthetic process formyltetrahydrofolate dehydrogenase activity oxidoreductase activity hydrolase activity ligase activity oxidation reduction	Glyoxylate and dicarboxylate metabolism One carbon pool by folate Metabolic pathways
202984_s_at	-0.330	6.697	-2.675	1.716e-02	0.207	-3.214	BAG5	BCL2-associated athanogene 5	14	-103092641, -103092641, -103092641	AA457021	9529	14q32.33	Hs.5443	10	protein binding protein folding apoptosis
205791_x_at	0.383	3.442	2.674	1.717e-02	0.207	-3.215	ZNF230	zinc finger protein 230	19	49198916	NM_006300	7773	19q13.31	Hs.193583	10	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552757_s_at	0.272	3.331	2.674	1.717e-02	0.207	-3.215	C9orf66	chromosome 9 open reading frame 66	9	-203107	AI478419	157983	9p24.3	Hs.190877	3
207814_at	0.205	5.797	2.674	1.718e-02	0.207	-3.215	DEFA6	defensin, alpha 6, Paneth cell-specific	8	-6769628	NM_001926	1671	8pter-p21	Hs.711	10	extracellular region extracellular space xenobiotic metabolic process defense response to bacterium defense response to fungus
200060_s_at	-0.254	9.425	-2.674	1.718e-02	0.207	-3.215	RNPS1	RNA binding protein S1, serine-rich domain	16	-2243122, -2243122	BC001659	10921	16p13.3	Hs.355643	30	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus cytoplasm transcription RNA splicing nuclear speck
210309_at	-0.213	4.443	-2.674	1.718e-02	0.207	-3.216	RECQL5	RecQ protein-like 5	17	-71158037, -71156539, -71134544	AB042823	9400	17q25.2-q25.3	Hs.632229	13	nucleotide binding nucleic acid binding DNA helicase activity ATP binding nucleus nucleoplasm cytoplasm DNA repair DNA recombination ATP-dependent helicase activity hydrolase activity
218543_s_at	0.313	5.664	2.674	1.719e-02	0.207	-3.216	PARP12	poly (ADP-ribose) polymerase family, member 12	7	-139370017	NM_022750	64761	7q34	Hs.12646	8	nucleic acid binding NAD+ ADP-ribosyltransferase activity nucleus zinc ion binding transferase activity metal ion binding
242157_at	0.483	4.464	2.674	1.719e-02	0.207	-3.216	CHD9	chromodomain helicase DNA binding protein 9	16	51646445	AW469037	80205	16q12.2	Hs.59159 Hs.622347	10	nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription
213174_at	-0.327	6.200	-2.674	1.720e-02	0.207	-3.216	TTC9	tetratricopeptide repeat domain 9	14	70178256	BE675549	23508	14q24.2	Hs.79170	5	binding protein folding
1554958_at	-0.299	4.625	-2.673	1.720e-02	0.207	-3.216	ZNF641	zinc finger protein 641	12	-47022178	BC018090	121274	12q13.11	Hs.23492	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201893_x_at	0.517	11.084	2.673	1.720e-02	0.207	-3.216	DCN	decorin	12	-90063165, -90063165, -90063165	AF138300	1634	12q21.33	Hs.718429	104	protein binding glycosaminoglycan binding extracellular region proteinaceous extracellular matrix organ morphogenesis peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix binding	TGF-beta signaling pathway
228312_at	0.274	6.222	2.673	1.722e-02	0.207	-3.217	PI16	peptidase inhibitor 16	6	37030186	AI524085	221476	6p21.2	Hs.25391	5	extracellular region membrane integral to membrane peptidase inhibitor activity
227721_at	0.274	4.804	2.673	1.723e-02	0.207	-3.218	CPAMD8	C3 and PZP-like, alpha-2-macroglobulin domain containing 8	19	-16864761	AB033109	27151	19p13.11	Hs.631644	8	serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space membrane
202607_at	0.260	6.590	2.672	1.723e-02	0.207	-3.218	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	5	149867866	AL526632	3340	5q33.1	Hs.222055	13	Golgi apparatus inflammatory response sulfotransferase activity heparan sulfate proteoglycan biosynthetic process [heparan sulfate]-glucosamine N-sulfotransferase activity membrane integral to membrane transferase activity hydrolase activity	Heparan sulfate biosynthesis Metabolic pathways
210624_s_at	0.503	6.565	2.672	1.726e-02	0.207	-3.220	ILVBL	ilvB (bacterial acetolactate synthase)-like	19	-15086784	BC000109	10994	19p13.1	Hs.78880	3	magnesium ion binding cellular_component biological_process membrane integral to membrane transferase activity thiamin pyrophosphate binding
231725_at	0.275	3.474	2.671	1.729e-02	0.208	-3.221	PCDHB2	protocadherin beta 2	5	140454420	NM_018936	56133	5q31	Hs.533023	10	calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion synaptic transmission synaptogenesis calcium-dependent cell-cell adhesion
214399_s_at	0.233	4.617	2.671	1.730e-02	0.208	-3.222	KRT4	keratin 4	12	-51486599	BF588953	3851	12q12-q13	Hs.654610	19	structural molecule activity cytoskeleton organization epithelial cell differentiation keratin filament negative regulation of epithelial cell proliferation
214279_s_at	-1.037	9.481	-2.670	1.730e-02	0.208	-3.222	NDRG2	NDRG family member 2	14	-20554761, -20554761	W74452	57447	14q11.2	Hs.525205	42	molecular_function nucleus cytoplasm Golgi apparatus centrosome cytosol multicellular organismal development nervous system development cell differentiation perinuclear region of cytoplasm
244043_at	-0.250	5.037	-2.670	1.732e-02	0.208	-3.222	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	3	-143154017	AI049624	7029	3q23	Hs.379018	14	transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding	Cell cycle
218664_at	0.362	7.982	2.670	1.732e-02	0.208	-3.223	MECR	mitochondrial trans-2-enoyl-CoA reductase	1	-29391971	NM_016011	51102	1p36.1-p35.1	Hs.183646	10	binding mitochondrion fatty acid biosynthetic process zinc ion binding oxidoreductase activity trans-2-enoyl-CoA reductase (NADPH) activity oxidation reduction	Fatty acid elongation in mitochondria Metabolic pathways
232422_at	0.377	5.022	2.670	1.732e-02	0.208	-3.223	A2LD1	AIG2-like domain 1	13	-99981810	BC001077	87769	13q32.3	Hs.350868	2
224817_at	0.345	8.160	2.670	1.733e-02	0.208	-3.223	SH3PXD2A	SH3 and PX domains 2A	10	-105343773	W93554	9644	10q24.33	Hs.594708	10	podosome protein binding cytoplasm cell communication phosphoinositide binding cell projection
224448_s_at	0.607	9.763	2.670	1.733e-02	0.208	-3.223	C6orf125	chromosome 6 open reading frame 125	6	-33773323	BC006007	84300	6p21.31	Hs.93235	3
224336_s_at	-0.324	5.069	-2.669	1.734e-02	0.208	-3.224	DUSP16	dual specificity phosphatase 16	12	-12520097	AB052156	80824	12p13	Hs.536535	12	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive	MAPK signaling pathway
224869_s_at	0.226	8.640	2.669	1.735e-02	0.208	-3.224	MRPS25	mitochondrial ribosomal protein S25	3	-15065022	AW341440	64432	3p25	Hs.715617	9	structural constituent of ribosome protein binding mitochondrion mitochondrial small ribosomal subunit ribosome translation
213081_at	0.236	5.685	2.668	1.737e-02	0.208	-3.225	ZBTB22	zinc finger and BTB domain containing 22	6	-33390160, -33390160, -4662321, -4662321, -4468375, -4468375	AL523144	9278	6p21.3	Hs.206770	9	DNA binding retinoid-X receptor activity protein binding intracellular nucleus zinc ion binding thyroid hormone receptor coactivator activity vitamin D receptor binding retinoic acid receptor binding regulation of transcription metal ion binding thyroid hormone receptor binding protein heterodimerization activity
217857_s_at	-0.305	6.586	-2.668	1.738e-02	0.208	-3.226	RBM8A	RNA binding motif protein 8A	1	144218994	NM_005105	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
1557120_at	0.562	5.319	2.668	1.738e-02	0.208	-3.226	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	6	-74282193	BE622780	1915	6q14.1	Hs.520703 Hs.586423 Hs.644639 Hs.697944 Hs.708256 Hs.713109	86	nucleotide binding translation elongation factor activity GTPase activity protein binding GTP binding cytoplasm cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation
226943_at	-0.291	8.425	-2.668	1.739e-02	0.208	-3.226	C12orf73	chromosome 12 open reading frame 73	12	-102868110	AA287457	728568	12q23.3	Hs.42547	2	extracellular region
202291_s_at	0.833	8.394	2.668	1.739e-02	0.208	-3.226	MGP	matrix Gla protein	12	-14926093	NM_000900	4256	12p13.1-p12.3	Hs.365706	45	cartilage condensation ossification extracellular matrix structural constituent calcium ion binding extracellular region proteinaceous extracellular matrix extracellular space endoplasmic reticulum multicellular organismal development response to nutrient structural constituent of bone response to mechanical stimulus response to hormone stimulus cell differentiation lung development regulation of bone mineralization protein complex calcium-dependent protein binding response to calcium ion
209014_at	0.416	8.529	2.668	1.740e-02	0.208	-3.227	MAGED1	melanoma antigen family D, 1	X	51562894, 51653437	AF217963	9500	Xp11.23	Hs.5258	29	transcription coactivator activity cytoplasm plasma membrane regulation of transcription from RNA polymerase II promoter identical protein binding regulation of apoptosis protein complex negative regulation of epithelial cell proliferation	Neurotrophin signaling pathway
206828_at	0.217	2.635	2.668	1.740e-02	0.208	-3.227	TXK	TXK tyrosine kinase	4	-47763166	NM_003328	7294	4p12	Hs.479669	16	nucleotide binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity	Leukocyte transendothelial migration
226561_at	-0.454	5.722	-2.667	1.741e-02	0.208	-3.227	AGFG1	ArfGAP with FG repeats 1	2	228045131	BE551849	3267	2q36.3	Hs.352962	29	DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding
213890_x_at	-0.343	12.550	-2.667	1.744e-02	0.208	-3.229	RPS16	ribosomal protein S16	19	-44615686	AI200589	6217	19q13.1	Hs.397609	24	RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
202221_s_at	-0.442	6.219	-2.667	1.744e-02	0.208	-3.229	EP300	E1A binding protein p300	22	39818559	AV727101	2033	22q13.2	Hs.517517	338	histone acetyltransferase complex response to hypoxia somitogenesis transcription factor activity transcription coactivator activity histone acetyltransferase activity nucleus transcription factor complex nucleolus cytoplasm regulation of transcription, DNA-dependent apoptosis cell cycle signal transduction nervous system development heart development skeletal muscle tissue development protein C-terminus binding zinc ion binding organ morphogenesis acetyltransferase activity histone acetylation transferase activity N-terminal peptidyl-lysine acetylation lung development homeostatic process peroxisome proliferator activated receptor binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter metal ion binding positive regulation of transcription factor activity	Cell cycle Wnt signaling pathway Notch signaling pathway TGF-beta signaling pathway Adherens junction Jak-STAT signaling pathway Long-term potentiation Melanogenesis Huntington's disease Pathways in cancer Renal cell carcinoma Prostate cancer
208890_s_at	0.441	5.185	2.666	1.745e-02	0.208	-3.229	PLXNB2	plexin B2	22	-49055534	BC004542	23654	22q13.33	Hs.3989	17	receptor activity protein binding intracellular signal transduction multicellular organismal development membrane integral to membrane positive regulation of axonogenesis	Axon guidance
209094_at	-0.808	9.209	-2.666	1.745e-02	0.208	-3.229	DDAH1	dimethylarginine dimethylaminohydrolase 1	1	-85556756, -85556756	AL078459	23576	1p22	Hs.379858	22	cytoplasm arginine catabolic process nitric oxide mediated signal transduction zinc ion binding dimethylargininase activity hydrolase activity metal ion binding
216092_s_at	-0.293	6.908	-2.666	1.747e-02	0.209	-3.230	SLC7A8	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8	14	-22664343, -22664343	AL365347	23428	14q11.2	Hs.632348	14	protein binding cytoplasm plasma membrane integral to plasma membrane cellular amino acid metabolic process transport response to toxin organic cation transmembrane transporter activity neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity neutral amino acid transport L-amino acid transport toxin transporter activity peptide antigen binding metal ion homeostasis
203885_at	-0.426	8.739	-2.666	1.748e-02	0.209	-3.231	RAB21	RAB21, member RAS oncogene family	12	70434924	NM_014999	23011	12q21.1	Hs.524590	12	Golgi membrane nucleotide binding protein binding GTP binding endosome endoplasmic reticulum Golgi apparatus small GTPase mediated signal transduction protein transport membrane cytoplasmic vesicle membrane cytoplasmic vesicle early endosome membrane
203376_at	-0.232	7.567	-2.665	1.750e-02	0.209	-3.232	CDC40	cell division cycle 40 homolog (S. cerevisiae)	6	110608316	BG528818	51362	6q21	Hs.428147	18	nuclear mRNA splicing, via spliceosome nucleus spliceosomal complex RNA splicing
207615_s_at	0.226	4.221	2.665	1.751e-02	0.209	-3.232	C16orf3	chromosome 16 open reading frame 3	16	-88622816	NM_001214	750	16q24.3	Hs.633032	3	molecular_function cellular_component biological_process
223520_s_at	0.271	3.710	2.665	1.751e-02	0.209	-3.232	KIF13A	kinesin family member 13A	6	-17871902, -17868563	AY014403	63971	6p23	Hs.189915	14	nucleotide binding microtubule motor activity protein binding ATP binding microtubule microtubule-based movement protein transport
204345_at	0.440	5.771	2.664	1.751e-02	0.209	-3.233	COL16A1	collagen, type XVI, alpha 1	1	-31890434	NM_001856	1307	1p35-p34	Hs.368921	11	integrin binding structural molecule activity protein binding extracellular region proteinaceous extracellular matrix collagen type XVI cell adhesion integrin-mediated signaling pathway female pregnancy
218517_at	-0.274	7.224	-2.664	1.753e-02	0.209	-3.233	PHF17	PHD finger protein 17	4	129950228, 129950228	NM_024900	79960	4q26-q27	Hs.12420	14	histone acetyltransferase complex protein binding nucleus cytoplasm apoptosis response to stress zinc ion binding negative regulation of cell growth histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation regulation of transcription metal ion binding
218905_at	-0.397	7.489	-2.664	1.754e-02	0.209	-3.234	INTS8	integrator complex subunit 8	8	95904709	NM_017864	55656	8q22.1	Hs.521693	8	protein binding nucleus snRNA processing integrator complex
225783_at	-0.354	8.452	-2.664	1.754e-02	0.209	-3.234	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	2	238540438	BF675985	140739	2q37.3	Hs.471785	4	nucleotide binding protein binding ATP binding ligase activity NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation regulation of protein metabolic process	Ubiquitin mediated proteolysis
227443_at	0.335	5.686	2.663	1.755e-02	0.209	-3.235	C9orf150	chromosome 9 open reading frame 150	9	12765011	AI972386	286343	9p23	Hs.445356	6
214820_at	-0.573	4.955	-2.663	1.756e-02	0.209	-3.235	BRWD1	bromodomain and WD repeat domain containing 1	21	-39590234, -39484017, -39479273	AJ002572	54014	21q22.2	Hs.654740	8	protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter biological_process transcription regulator activity regulation of transcription
204779_s_at	0.375	4.610	2.663	1.756e-02	0.209	-3.235	HOXB7	homeobox B7	17	-44039593	NM_004502	3217	17q21.3	Hs.436181	39	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation myeloid cell differentiation sequence-specific DNA binding embryonic skeletal system morphogenesis
226750_at	-0.471	6.597	-2.663	1.757e-02	0.209	-3.235	LARP1B	La ribonucleoprotein domain family, member 1B	4	129201952, 129201952, 129201952	AI767732	55132	4q28.2	Hs.657067	3	RNA binding
218315_s_at	-0.328	7.100	-2.661	1.762e-02	0.210	-3.238	CDK5RAP1	CDK5 regulatory subunit associated protein 1	20	-31410305	NM_016408	51654	20pter-q11.23	Hs.435952	13	catalytic activity iron ion binding protein binding cellular_component brain development neuronal Cdc2-like kinase binding regulation of neuron differentiation negative regulation of cyclin-dependent protein kinase activity metal ion binding 4 iron, 4 sulfur cluster binding
222882_s_at	0.212	5.367	2.661	1.762e-02	0.210	-3.238	C17orf59	chromosome 17 open reading frame 59	17	-8032375	AI992271	54785	17p13.1	Hs.129563	3	protein binding
209156_s_at	0.499	6.596	2.661	1.763e-02	0.210	-3.238	COL6A2	collagen, type VI, alpha 2	21	46342460, 46342460	AY029208	1292	21q22.3	Hs.420269	37	extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix membrane cell-cell adhesion extracellular matrix organization protein binding, bridging sarcolemma	Focal adhesion ECM-receptor interaction
213260_at	0.251	6.273	2.661	1.764e-02	0.210	-3.239	FOXC1	forkhead box C1	6	1555679	AU145890	2296	6p25	Hs.348883	51	skeletal system development ossification ovarian follicle development blood vessel development ureteric bud development in utero embryonic development kidney development lymph vessel development blood vessel remodeling heart morphogenesis RNA polymerase II transcription factor activity, enhancer binding nucleus nucleus nuclear heterochromatin anti-apoptosis Notch signaling pathway brain development transcription factor binding DNA bending activity germ cell migration neural crest cell development transcription activator activity collagen fibril organization glycosaminoglycan metabolic process lacrimal gland development embryonic heart tube development odontogenesis of dentine-containing tooth camera-type eye development sequence-specific DNA binding negative regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter regulation of organ growth vascular endothelial growth factor receptor signaling pathway paraxial mesoderm formation mesenchymal cell differentiation artery morphogenesis regulation of blood vessel size ventricular cardiac muscle morphogenesis cardiac muscle cell proliferation
204104_at	0.278	5.541	2.661	1.764e-02	0.210	-3.239	SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa	19	7891228	NM_003083	6618	19p13.3-p13.2	Hs.631860	12	transcription factor activity nucleus transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter snRNA transcription regulation of transcription
214113_s_at	-0.396	7.575	-2.661	1.765e-02	0.210	-3.239	RBM8A	RNA binding motif protein 8A	1	144218994	AI738479	9939	1q12	Hs.356873	43	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport
216294_s_at	-0.334	4.775	-2.661	1.765e-02	0.210	-3.240	KIAA1109	KIAA1109	4	123311207	AL137254	84162	4q27	Hs.408142	12	membrane integral to membrane
209666_s_at	-0.560	6.313	-2.660	1.768e-02	0.210	-3.241	CHUK	conserved helix-loop-helix ubiquitous kinase	10	-101938113	AF080157	1147	10q24-q25	Hs.198998	154	nucleotide binding morphogenesis of an epithelial sheet ATP binding nucleus cytoplasm cytosol immune response I-kappaB phosphorylation IkappaB kinase activity anatomical structure morphogenesis transferase activity osteoclast differentiation odontogenesis of dentine-containing tooth identical protein binding	MAPK signaling pathway Chemokine signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Pancreatic cancer Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer
1557100_s_at	-0.591	6.355	-2.659	1.769e-02	0.210	-3.242	HECTD1	HECT domain containing 1	14	-30639074	AL038005	25831	14q12	Hs.708017	7	ubiquitin-protein ligase activity binding intracellular protein modification process protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process metal ion binding
214172_x_at	-0.292	5.901	-2.659	1.770e-02	0.210	-3.242	RYK	RYK receptor-like tyrosine kinase	3	-135358667	BG032035	6259	3q22	Hs.654562	13	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction axonogenesis transferase activity Wnt-protein binding Wnt receptor activity skeletal system morphogenesis
202958_at	0.263	5.968	2.659	1.770e-02	0.210	-3.242	PTPN9	protein tyrosine phosphatase, non-receptor type 9	15	-73546514	NM_002833	5780	15q24.2	Hs.445775	13	non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm protein amino acid dephosphorylation hydrolase activity
229204_at	-0.426	5.855	-2.659	1.771e-02	0.210	-3.243	HP1BP3	heterochromatin protein 1, binding protein 3	1	-20941757	BE218428	50809	1p36.12	Hs.142442	3	nucleosome DNA binding nucleus chromosome nucleosome assembly
214182_at	-0.465	6.108	-2.659	1.771e-02	0.210	-3.243	ARF6	ADP-ribosylation factor 6	14	49429485	AA243143	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
230100_x_at	-0.392	5.287	-2.659	1.772e-02	0.210	-3.243	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	11	-76710707	AU147145	5058	11q13-q14	Hs.435714	190	MAPKKK cascade nucleotide binding protein serine/threonine kinase activity collagen binding ATP binding cytoplasm Golgi apparatus plasma membrane focal adhesion apoptosis ER-nuclear signaling pathway cytoskeleton organization transferase activity cell junction positive regulation of JUN kinase activity protein amino acid autophosphorylation	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Axon guidance Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma
201513_at	-0.459	6.391	-2.659	1.772e-02	0.210	-3.243	TSN	translin	2	122229590	AI659180	7247	2q21.1	Hs.75066	28	nucleus cytoplasm DNA recombination sequence-specific DNA binding
201634_s_at	-0.597	6.283	-2.658	1.773e-02	0.210	-3.244	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	16	68015998	NM_030579	80777	16q22.1	Hs.461131	7	mitochondrion mitochondrial outer membrane mitochondrial inner membrane microsome transport enzyme activator activity membrane integral to membrane heme binding electron transport chain metal ion binding
219223_at	0.246	6.888	2.658	1.773e-02	0.210	-3.244	C9orf7	chromosome 9 open reading frame 7	9	135314907	NM_017586	11094	9q34	Hs.62003	7	molecular_function cellular_component biological_process membrane integral to membrane
218550_s_at	-0.406	8.158	-2.658	1.774e-02	0.210	-3.244	LRRC20	leucine rich repeat containing 20	10	-71728734, -71728734	NM_018205	55222	10q22.1	Hs.7778	5	protein binding
202425_x_at	-0.381	8.582	-2.658	1.775e-02	0.210	-3.245	PPP3CA	protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform	4	-102163609	NM_000944	5530	4q21-q24	Hs.435512	59	protein serine/threonine phosphatase activity iron ion binding calcium ion binding calmodulin binding nucleus cytoplasm calcineurin complex protein amino acid dephosphorylation zinc ion binding hydrolase activity	MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
240459_at	-0.240	3.787	-2.658	1.775e-02	0.210	-3.245	YTHDC1	YTH domain containing 1	4	-68858699	AW467048	91746	4q13.2	Hs.175955	18	nucleus mRNA processing RNA splicing
1555763_x_at	-0.285	4.166	-2.657	1.777e-02	0.210	-3.246	MKL1	megakaryoblastic leukemia (translocation) 1	22	-39136237	AF364036	57591	22q13	Hs.654688	37	nucleic acid binding transcription coactivator activity actin monomer binding protein binding nucleus cytoplasm anti-apoptosis positive regulation of transcription
216232_s_at	-0.241	7.364	-2.657	1.779e-02	0.211	-3.247	GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	12	-119049396	AI697055	10985	12q24.2	Hs.298716	11	protein binding cytoplasm ribosome regulation of translation translation factor activity, nucleic acid binding
202750_s_at	-0.405	6.999	-2.657	1.779e-02	0.211	-3.247	TFIP11	tuftelin interacting protein 11	22	-25217894	AL080147	24144	22q12.1	Hs.20225	19	nucleic acid binding protein binding proteinaceous extracellular matrix intracellular nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing nuclear speck biomineral formation
208149_x_at	0.412	5.717	2.657	1.780e-02	0.211	-3.247	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	12	31118045	NM_030653	1663	12p11	Hs.443960	13	mitotic sister chromatid segregation S phase of mitotic cell cycle G2/M transition of mitotic cell cycle nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP binding nucleus nucleolus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle positive regulation of cell proliferation hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
203961_at	0.348	4.351	2.656	1.781e-02	0.211	-3.248	NEBL	nebulette	10	-21108910, -21108910	AL157398	10529	10p12	Hs.5025	15	actin binding structural constituent of muscle regulation of actin filament length
235076_at	-0.400	7.223	-2.656	1.781e-02	0.211	-3.248	CALCOCO2	calcium binding and coiled-coil domain 2	17	44263370	AA149539	10241	17q21.32	Hs.514920	11	protein binding soluble fraction nucleus cytoplasm Golgi apparatus cytoskeleton viral reproduction response to interferon-gamma protein homodimerization activity perinuclear region of cytoplasm
224385_s_at	0.184	3.337	2.656	1.782e-02	0.211	-3.248	MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)	22	48870561, 48870811, 48927610	AF285604	54456	22q13.33	Hs.62880	7	nucleotide binding magnesium ion binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding intracellular multicellular organismal development germ cell development spermatogenesis muscle organ development cell proliferation hydrolase activity negative regulation of cell cycle
229957_at	0.307	5.677	2.656	1.782e-02	0.211	-3.249	TMEM91	transmembrane protein 91	19	46561710, 46574277, 46575008	BF446281	641649	19q13.2	Hs.709417	4	response to biotic stimulus membrane integral to membrane
201856_s_at	-0.449	5.459	-2.656	1.783e-02	0.211	-3.249	ZFR	zinc finger RNA binding protein	5	-32390212	BC000376	51663	5p13.3	Hs.435231	6	DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding
211663_x_at	0.566	7.375	2.655	1.785e-02	0.211	-3.250	PTGDS	prostaglandin D2 synthase 21kDa (brain)	9	138991776	M61900	5730	9q34.2-q34.3	Hs.446429	63	prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm	Arachidonic acid metabolism Metabolic pathways
201743_at	0.726	5.245	2.655	1.786e-02	0.211	-3.250	CD14	CD14 molecule	5	-139991500, -139991500	NM_000591	929	5q22-q32 5q31.1	Hs.163867	362	opsonin receptor activity response to molecule of bacterial origin protein binding extracellular region plasma membrane plasma membrane phagocytosis apoptosis inflammatory response immune response cell surface receptor linked signal transduction peptidoglycan receptor activity anchored to membrane membrane raft lipopolysaccharide receptor complex	MAPK signaling pathway Toll-like receptor signaling pathway Hematopoietic cell lineage Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
216220_s_at	0.245	6.332	2.655	1.786e-02	0.211	-3.251	ADORA1	adenosine A1 receptor	1	201363458	X68485	134	1q32.1	Hs.77867	58	adenosine receptor activity, G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane phagocytosis inflammatory response signal transduction G-protein coupled receptor protein signaling pathway cell-cell signaling nervous system development induction of apoptosis by extracellular signals	Neuroactive ligand-receptor interaction
200685_at	-0.272	7.117	-2.655	1.787e-02	0.211	-3.251	SFRS11	splicing factor, arginine/serine-rich 11	1	70443952	AU146237	9295	1p31	Hs.479693	13	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleolus RNA splicing
200746_s_at	0.241	7.435	2.655	1.787e-02	0.211	-3.251	GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	1	-1706588	NM_002074	2782	1p36.33	Hs.430425 Hs.709208	54	G-protein-coupled receptor binding photoreceptor outer segment GTPase activity signal transducer activity heterotrimeric G-protein complex signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration muscarinic acetylcholine receptor signaling pathway Ras protein signal transduction cell proliferation hormone-mediated signaling type 1 angiotensin receptor binding sensory perception of taste	Chemokine signaling pathway Taste transduction
208916_at	0.270	5.633	2.654	1.788e-02	0.211	-3.252	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	19	-51969981, -51969981, -51969981	AF105230	6510	19q13.3	Hs.631582	27	receptor activity protein binding membrane fraction integral to plasma membrane transport dicarboxylic acid transport extracellular amino acid transport neutral amino acid transmembrane transporter activity symporter activity neutral amino acid transport membrane sodium:dicarboxylate symporter activity melanosome
225217_s_at	-0.391	5.673	-2.653	1.791e-02	0.211	-3.253	BRPF3	bromodomain and PHD finger containing, 3	6	36272527	AB033112	27154	6p21	Hs.520096	6	histone acetyltransferase complex protein binding zinc ion binding histone H3 acetylation metal ion binding
219456_s_at	0.211	3.966	2.653	1.792e-02	0.211	-3.253	RIN3	Ras and Rab interactor 3	14	92049877	AW027923	79890	14q32.12	Hs.326822	8	GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle
218675_at	0.267	5.218	2.653	1.792e-02	0.211	-3.253	SLC22A17	solute carrier family 22, member 17	14	-22885378, -22885366	NM_020372	51310	14q11.2	Hs.373498	6	transporter activity ion transport membrane integral to membrane
240715_at	0.301	4.722	2.653	1.793e-02	0.211	-3.254	TBX5	T-box 5	12	-113288284, -113276117, -113276117	AW269421	6910	12q24.1	Hs.381715	37	transcription factor activity RNA polymerase II transcription factor activity nucleus cytoplasm induction of apoptosis cell-cell signaling multicellular organismal development heart development heart development heart development transcription factor binding positive regulation of specific transcription from RNA polymerase II promoter embryonic limb morphogenesis negative regulation of cell migration embryonic arm morphogenesis forelimb morphogenesis sequence-specific DNA binding positive regulation of transcription, DNA-dependent positive regulation of cardioblast differentiation pericardium development negative regulation of cardiac muscle cell proliferation
225310_at	-0.290	7.261	-2.652	1.794e-02	0.211	-3.254	RBMX	RNA binding motif protein, X-linked	X	-135783284	AI928344	27316	Xq26.3	Hs.380118 Hs.710162	32	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex biological_process RNA splicing heterogeneous nuclear ribonucleoprotein complex
227179_at	-0.304	8.385	-2.652	1.794e-02	0.211	-3.255	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)	8	-74624394	AK002152	27067	8q13-q21.1	Hs.561815	11	double-stranded RNA binding intracellular nucleus nucleolus cytoplasm endoplasmic reticulum microtubule transport
227792_at	-0.289	7.361	-2.651	1.798e-02	0.212	-3.256	ITPRIPL2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	16	19032754	AA490685	162073	16p12.3	Hs.530899 Hs.648523	3	membrane integral to membrane
203079_s_at	-0.410	7.446	-2.651	1.799e-02	0.212	-3.257	CUL2	cullin 2	10	-35338811	NM_003591	8453	10p11.21	Hs.82919	35	G1/S transition of mitotic cell cycle protein binding ubiquitin-dependent protein catabolic process cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding interspecies interaction between organisms	Ubiquitin mediated proteolysis Pathways in cancer Renal cell carcinoma
235070_at	-0.303	8.267	-2.651	1.800e-02	0.212	-3.257	A2BP1	ataxin 2-binding protein 1	16	6009132, 6763810, 7322751	AL133898	54715	16p13.3	Hs.459842	22	nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport
232515_at	0.219	6.190	2.651	1.800e-02	0.212	-3.257	ASB3	ankyrin repeat and SOCS box-containing 3	2	-53750621	AU144567	51130	2p16-p14	Hs.40763	10	intracellular signaling cascade modification-dependent protein catabolic process
208786_s_at	-0.439	9.127	-2.651	1.800e-02	0.212	-3.258	MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	16	85983301	AF183417	81631	16q24.2	Hs.356061	22	protein binding intracellular cytoplasm autophagic vacuole microtubule autophagy modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
210277_at	-0.527	6.521	-2.651	1.800e-02	0.212	-3.258	AP4S1	adaptor-related protein complex 4, sigma 1 subunit	14	30564433, 30564433	AF155159	11154	14q12	Hs.293411	4	transporter activity protein binding Golgi apparatus coated pit intracellular protein transport protein transporter activity membrane vesicle-mediated transport membrane coat	Lysosome
224036_s_at	-0.392	5.328	-2.651	1.800e-02	0.212	-3.258	LMBR1	limb region 1 homolog (mouse)	7	-156166330	AF063592	64327	7q36	Hs.209989	24	receptor activity membrane integral to membrane
231779_at	-0.441	6.289	-2.651	1.800e-02	0.212	-3.258	IRAK2	interleukin-1 receptor-associated kinase 2	3	10181562	AI246590	3656	3p25.3	Hs.449207	15	regulation of cytokine-mediated signaling pathway MyD88-dependent toll-like receptor signaling pathway protein kinase activity NF-kappaB-inducing kinase activity ATP binding protein amino acid phosphorylation inflammatory response signal transduction I-kappaB kinase/NF-kappaB cascade cell surface lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity protein homodimerization activity protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway response to interleukin-1	Apoptosis Neurotrophin signaling pathway
201189_s_at	0.231	6.302	2.650	1.802e-02	0.212	-3.259	ITPR3	inositol 1,4,5-triphosphate receptor, type 3	6	33697138	NM_002224	3710	6p21	Hs.65758	40	inositol hexakisphosphate binding ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding protein binding nucleus nuclear outer membrane nucleoplasm nucleolus cytoplasm endoplasmic reticulum microsome integral to plasma membrane brush border ion transport calcium ion transport G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration membrane phosphoinositide binding cell soma myelin sheath inositol 1,3,4,5 tetrakisphosphate binding apical part of cell sensory perception of bitter taste sensory perception of sweet taste sensory perception of umami taste protein homooligomerization protein heterooligomerization response to calcium ion inositol 1,4,5 trisphosphate binding	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression Taste transduction GnRH signaling pathway Alzheimer's disease
228424_at	0.291	5.898	2.650	1.803e-02	0.212	-3.259	NAALADL1	N-acetylated alpha-linked acidic dipeptidase-like 1	11	-64568870	AW170591	10004	11q12	Hs.13967	3	carboxypeptidase activity plasma membrane proteolysis peptidase activity metallopeptidase activity zinc ion binding integral to membrane dipeptidase activity metal ion binding
212757_s_at	-0.495	8.897	-2.650	1.803e-02	0.212	-3.259	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	10	-75242264, -75242264	BF111268	818	10q22	Hs.523045	75	nucleotide binding calmodulin-dependent protein kinase activity calcium-dependent protein serine/threonine phosphatase activity calmodulin binding ATP binding cellular_component calcium- and calmodulin-dependent protein kinase complex protein amino acid phosphorylation transferase activity insulin secretion	ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma
213423_x_at	0.416	6.020	2.650	1.803e-02	0.212	-3.259	TUSC3	tumor suppressor candidate 3	8	15442100	AI884858	7991	8p22	Hs.591845	13	dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum oligosaccharyltransferase complex membrane integral to membrane protein amino acid N-linked glycosylation via asparagine
234307_s_at	0.361	6.269	2.650	1.804e-02	0.212	-3.260	KIF26A	kinesin family member 26A	14	103674812	AK026406	26153	14q32.33	Hs.134970	3	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement
217898_at	-0.294	8.557	-2.649	1.805e-02	0.212	-3.260	C15orf24	chromosome 15 open reading frame 24	15	-32163515	NM_020154	56851	15q14	Hs.160565	6	cytoplasm biological_process membrane integral to membrane purine nucleotide binding
1554333_at	-0.991	6.512	-2.649	1.806e-02	0.212	-3.261	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	15	76343541, 76344043, 76345614	BC031044	55466	15q25.1	Hs.513053	5	protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding
223547_at	-0.442	5.665	-2.649	1.807e-02	0.212	-3.261	JKAMP	JNK1/MAPK8-associated membrane protein	14	59020913	AL038769	51528	14q23.1	Hs.446850	12	plasma membrane integral to membrane
213000_at	-0.405	6.932	-2.649	1.807e-02	0.212	-3.261	MORC3	MORC family CW-type zinc finger 3	21	36614356	AP000693	23515	21q22.13	Hs.421150	11	ATP binding cell aging zinc ion binding PML body peptidyl-serine phosphorylation metal ion binding negative regulation of fibroblast proliferation protein stabilization maintenance of protein location in nucleus
227158_at	0.277	5.485	2.649	1.807e-02	0.212	-3.261	C14orf126	chromosome 14 open reading frame 126	14	-30984993	AU149257	112487	14q12	Hs.116014	4	cytoplasm hydrolase activity, acting on ester bonds D-amino acid catabolic process
230847_at	0.260	3.855	2.649	1.808e-02	0.212	-3.261	WRNIP1	Werner helicase interacting protein 1	6	2710664	T79870	56897	6p25.2	Hs.236828	14	nucleotide binding DNA synthesis during DNA repair DNA binding protein binding protein binding ATP binding nucleus response to DNA damage stimulus hydrolase activity ATPase activity regulation of DNA replication initiation
226257_x_at	0.308	8.986	2.649	1.808e-02	0.212	-3.262	MRPS22	mitochondrial ribosomal protein S22	3	140545550	AA631191	56945	3q23	Hs.75724	13	molecular_function structural constituent of ribosome protein binding mitochondrion mitochondrial small ribosomal subunit ribosome biological_process
204313_s_at	-0.292	6.396	-2.648	1.809e-02	0.212	-3.262	CREB1	cAMP responsive element binding protein 1	2	208102860	AA161486	1385	2q34	Hs.516646	215	transcription factor activity transcription cofactor activity nucleus nucleoplasm regulation of transcription, DNA-dependent protein amino acid phosphorylation signal transduction response to organic substance sequence-specific DNA binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter protein dimerization activity	Antigen processing and presentation Melanogenesis Huntington's disease Prostate cancer
1555250_a_at	-0.527	6.887	-2.648	1.809e-02	0.212	-3.262	CPEB3	cytoplasmic polyadenylation element binding protein 3	10	-93798378	BC036444	22849	10q23.32	Hs.131683	7	nucleotide binding RNA binding
211441_x_at	-0.223	3.690	-2.648	1.809e-02	0.212	-3.262	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	7	99263571	AF280113	64816	7q21.1	Hs.306220 Hs.654391 Hs.695915	17	endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	gamma-Hexachlorocyclohexane degradation Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
200847_s_at	-0.438	9.716	-2.648	1.810e-02	0.212	-3.263	TMEM66	transmembrane protein 66	8	-30040172	NM_016127	51669	8p12	Hs.521487	10	membrane integral to membrane
223276_at	0.540	6.329	2.648	1.810e-02	0.212	-3.263	MST150	MSTP150	5	150138059	AF313413	85027	5q33.1	Hs.29444	4	membrane integral to membrane
220184_at	0.433	4.792	2.647	1.814e-02	0.212	-3.265	NANOG	Nanog homeobox	12	7833261	NM_024865	79923	12p13.31	Hs.661360	42	transcription factor activity nucleus regulation of transcription, DNA-dependent cell proliferation embryonic development sequence-specific DNA binding regulation of cell differentiation
222438_at	-0.536	4.948	-2.647	1.815e-02	0.212	-3.265	MED4	mediator complex subunit 4	13	-47548092	AK001934	29079	13q14.2	Hs.181112	21	transcription cofactor activity receptor activity protein binding nucleus nucleolus cytoplasm regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity transcription activator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription thyroid hormone receptor binding
229084_at	0.359	4.052	2.646	1.816e-02	0.213	-3.265	CNTN4	contactin 4	3	2117246, 2908920, 3056307	R42166	152330	3p26-p25	Hs.298705	16	protein binding extracellular region plasma membrane cell adhesion neuron adhesion nervous system development axon guidance axonal fasciculation brain development axon neuron projection development anchored to membrane negative regulation of neuron differentiation regulation of synaptic plasticity
202271_at	-0.270	7.657	-2.646	1.817e-02	0.213	-3.266	FBXO28	F-box protein 28	1	222368413	AB007952	23219	1q42.11	Hs.64691 Hs.713992	10	modification-dependent protein catabolic process
217730_at	-0.336	8.118	-2.646	1.819e-02	0.213	-3.267	TMBIM1	transmembrane BAX inhibitor motif containing 1	2	-218847160	NM_022152	64114	2p24.3-p24.1	Hs.591605	9	membrane integral to membrane
217555_at	-0.273	5.076	-2.645	1.820e-02	0.213	-3.267	SMC1A	structural maintenance of chromosomes 1A	X	-53417794	AI042030	8243	Xp11.22-p11.21	Hs.211602	47	cell cycle checkpoint nucleotide binding nuclear mRNA splicing, via spliceosome condensed chromosome kinetochore condensed nuclear chromosome chromatin binding microtubule motor activity protein binding ATP binding nucleus chromosome cytoplasm DNA repair response to DNA damage stimulus cell cycle mitotic spindle organization mitotic sister chromatid cohesion meiosis cohesin core heterodimer response to radiation DNA damage response, signal transduction protein heterodimerization activity chromosome organization cell division	Cell cycle
224631_at	-0.402	6.839	-2.645	1.821e-02	0.213	-3.268	ZFP91	zinc finger protein 91 homolog (mouse)	11	58103162	AA758013	80829	11q12	Hs.524920	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
33736_at	0.355	7.107	2.645	1.821e-02	0.213	-3.268	STOML1	stomatin (EPB72)-like 1	15	-72062612	Y16522	9399	15q24-q25	Hs.194816	9	molecular_function sterol carrier activity cellular_component biological_process membrane integral to membrane
209404_s_at	-0.341	6.153	-2.644	1.823e-02	0.213	-3.269	TMED7	transmembrane emp24 protein transport domain containing 7	5	-114977101	AF151867	51014	5q22.3	Hs.642817 Hs.710895	7	endoplasmic reticulum transport membrane integral to membrane
1562761_at	-0.195	2.729	-2.644	1.824e-02	0.213	-3.270	C9orf95	chromosome 9 open reading frame 95	9	-76865935	BC026243	54981	9q21.13	Hs.494186	6	nucleotide binding magnesium ion binding ATP binding transferase activity pyridine nucleotide biosynthetic process ribosylnicotinamide kinase activity	Nicotinate and nicotinamide metabolism
201989_s_at	-0.256	6.877	-2.644	1.825e-02	0.213	-3.270	CREBL2	cAMP responsive element binding protein-like 2	12	12656097	AL529409	1389	12p13	Hs.591156	5	transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle signal transduction sequence-specific DNA binding protein dimerization activity
205595_at	0.230	5.158	2.644	1.827e-02	0.213	-3.271	DSG3	desmoglein 3 (pemphigus vulgaris antigen)	18	27281729	NM_001944	1830	18q12.1-q12.2	Hs.1925	51	calcium ion binding protein binding cytosol plasma membrane plasma membrane cell adhesion homophilic cell adhesion integral to membrane cell junction desmosome
204043_at	0.375	5.508	2.643	1.829e-02	0.213	-3.272	TCN2	transcobalamin II; macrocytic anemia	22	29333160	NM_000355	6948	22q12.2	Hs.417948	60	extracellular region extracellular space ion transport cobalt ion transport cobalt ion transmembrane transporter activity cobalamin transport cobalamin binding cobalt ion binding
209921_at	0.704	4.407	2.643	1.829e-02	0.213	-3.272	SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	4	-139304697	AB040875	23657	4q28-q32	Hs.390594	23	transport amino acid transport amino acid transmembrane transporter activity cystine:glutamate antiporter activity membrane integral to membrane
57163_at	0.271	5.760	2.643	1.829e-02	0.213	-3.272	ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	1	-43601658	H93026	64834	1p34.2	Hs.25597	7	protein binding endoplasmic reticulum fatty acid biosynthetic process membrane integral to membrane
241742_at	0.254	4.624	2.643	1.830e-02	0.213	-3.272	PRAM1	PML-RARA regulated adaptor molecule 1	19	-8460939	AW027174	84106	19p13.2	Hs.465812	12	integrin-mediated signaling pathway lipid binding regulation of neutrophil degranulation
224061_at	0.291	6.347	2.642	1.833e-02	0.214	-3.274	INMT	indolethylamine N-methyltransferase	7	30758275	AF128846	11185	7p15.3-p15.2	Hs.632629	6	cytoplasm methyltransferase activity transferase activity amine N-methyltransferase activity	Tryptophan metabolism
214311_at	0.224	6.259	2.642	1.833e-02	0.214	-3.274	ZFPL1	zinc finger protein-like 1	11	64608269	AI767884	7542	11q13	Hs.714995 Hs.98170	8	DNA binding protein binding nucleus Golgi apparatus zinc ion binding membrane integral to membrane vesicle-mediated transport regulation of transcription metal ion binding
226477_at	-0.299	5.647	-2.642	1.833e-02	0.214	-3.274	VPRBP	Vpr (HIV-1) binding protein	3	-51408337	AK023239	9730	3p21.2	Hs.716623	14	binding cytoplasm modification-dependent protein catabolic process interspecies interaction between organisms
203614_at	-0.270	7.574	-2.642	1.833e-02	0.214	-3.274	UTP14C	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)	13	51496827	NM_021645	9724	13q14.2	Hs.512963	7	nucleus nucleolus rRNA processing meiosis multicellular organismal development spermatogenesis cell differentiation small-subunit processome
231919_at	-0.340	6.052	-2.642	1.834e-02	0.214	-3.274	DBT	dihydrolipoamide branched chain transacylase E2	1	-100425065	AK024946	1629	1p31	Hs.709187	34	protein binding mitochondrion mitochondrial alpha-ketoglutarate dehydrogenase complex metabolic process acyltransferase activity transferase activity lipoic acid binding mitochondrial nucleoid dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity acyl-CoA biosynthetic process cofactor binding	Valine, leucine and isoleucine degradation Metabolic pathways
216693_x_at	0.392	5.548	2.641	1.835e-02	0.214	-3.275	HDGFRP3	hepatoma-derived growth factor, related protein 3	15	-81597819	AL133102	50810	15q25.2	Hs.513954	9	nucleus cytoplasm growth factor activity cell proliferation
1558894_a_at	-0.293	4.077	-2.641	1.837e-02	0.214	-3.276	CCDC67	coiled-coil domain containing 67	11	92703530	AK058122	159989	11q21	Hs.436625	2
207233_s_at	-0.310	8.486	-2.641	1.837e-02	0.214	-3.276	MITF	microphthalmia-associated transcription factor	3	69871322, 69895651, 69998131, 70010945, 70068442	NM_000248	4286	3p14.2-p14.1	Hs.166017 Hs.618266	93	DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation	Melanogenesis Pathways in cancer Melanoma
223886_s_at	-0.225	9.888	-2.641	1.837e-02	0.214	-3.276	RNF146	ring finger protein 146	6	127629712	AL136829	81847	6q22.1-q22.33	Hs.267120	12	protein binding zinc ion binding metal ion binding
205930_at	-0.392	6.681	-2.640	1.838e-02	0.214	-3.276	GTF2E1	general transcription factor IIE, polypeptide 1, alpha 56kDa	3	121944247	NM_005513	2960	3q21-q24	Hs.445272	41	RNA polymerase II transcription factor activity protein binding nucleus nucleoplasm transcription factor TFIIE complex transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter zinc ion binding regulation of transcription metal ion binding	Basal transcription factors
202329_at	0.369	5.408	2.640	1.838e-02	0.214	-3.276	CSK	c-src tyrosine kinase	15	72861477	NM_004383	1445	15q23-q25	Hs.77793	130	nucleotide binding non-membrane spanning protein tyrosine kinase activity ATP binding cytoplasm plasma membrane plasma membrane cell-cell junction protein amino acid phosphorylation protein C-terminus binding negative regulation of cell proliferation transferase activity	Chemokine signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Epithelial cell signaling in Helicobacter pylori infection
225501_at	-0.308	6.691	-2.640	1.839e-02	0.214	-3.277	PHF6	PHD finger protein 6	X	133335007, 133335007	AK027039	84295	Xq26.3	Hs.356501	16	protein binding nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
209983_s_at	0.231	4.224	2.640	1.839e-02	0.214	-3.277	NRXN2	neurexin 2	11	-64130221, -64130221	AB035266	9379	11q13	Hs.372938	16	calcium ion binding protein binding cell adhesion membrane integral to membrane	Cell adhesion molecules (CAMs)
223924_at	0.442	4.119	2.639	1.842e-02	0.214	-3.278	TTC25	tetratricopeptide repeat domain 25	17	37340413	AL136760	83538	17q21.2	Hs.201134	8	protein binding cytoplasm
208783_s_at	-0.335	8.333	-2.639	1.844e-02	0.214	-3.279	CD46	CD46 molecule, complement regulatory protein	1	205992024	AL570661	4179	1q32	Hs.510402	112	receptor activity plasma membrane integral to plasma membrane complement activation, classical pathway single fertilization interspecies interaction between organisms innate immune response	Complement and coagulation cascades
209386_at	0.364	8.896	2.639	1.845e-02	0.214	-3.280	TM4SF1	transmembrane 4 L six family member 1	3	-150569494	AI346835	4071	3q21-q25	Hs.715499	16	molecular_function integral to plasma membrane biological_process membrane
229521_at	0.287	5.344	2.638	1.845e-02	0.214	-3.280	FLJ36031	hypothetical protein FLJ36031	7	-106086384	BE466274	168455	7q22.3	Hs.29692	5
207117_at	0.453	2.631	2.638	1.846e-02	0.214	-3.280	ZNF117	zinc finger protein 117	7	-64072264	NM_015852	51351	7q11.21	Hs.250693	5	molecular_function transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding metal ion binding
226916_x_at	-0.235	6.304	-2.638	1.846e-02	0.214	-3.280	DPP9	dipeptidyl-peptidase 9	19	-4626243	AW190431	91039	19p13.3	Hs.515081	14	aminopeptidase activity cytoplasm cytosol proteolysis peptidase activity serine-type peptidase activity membrane
204483_at	-0.588	13.028	-2.638	1.847e-02	0.214	-3.281	ENO3	enolase 3 (beta, muscle)	17	4795130	NM_001976	2027	17pter-p11	Hs.224171	11	phosphopyruvate hydratase complex magnesium ion binding phosphopyruvate hydratase activity cytoplasm glycolysis lyase activity	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways RNA degradation
210091_s_at	-0.318	7.854	-2.638	1.847e-02	0.214	-3.281	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U46745	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
230620_at	0.234	5.409	2.637	1.850e-02	0.214	-3.282	USP27X	ubiquitin specific peptidase 27, X-linked	X	49531209	BE550967	389856	Xp11.23	Hs.143587	3	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
202610_s_at	-0.599	7.381	-2.637	1.851e-02	0.214	-3.283	MED14	mediator complex subunit 14	X	-40393738	AF135802	9282	Xp11.4-p11.2	Hs.407604	33	receptor activity protein binding nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
226548_at	0.293	7.623	2.637	1.851e-02	0.214	-3.283	SBK1	SH3-binding domain kinase 1	16	28211340	AI935915	388228	16p11.2	Hs.97837	3	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity
239356_at	0.229	4.258	2.637	1.852e-02	0.214	-3.283	LOC100129122	hypothetical LOC100129122	13		AA603474	100129122	13q32.3
219175_s_at	-0.342	6.998	-2.636	1.853e-02	0.214	-3.284	SLC41A3	solute carrier family 41, member 3	3	-127207889, -127207889	NM_017836	54946	3q21.2-q21.3	Hs.573007	5	plasma membrane cation transport cation transmembrane transporter activity integral to membrane
212375_at	-0.236	6.623	-2.636	1.853e-02	0.214	-3.284	EP400	E1A binding protein p400	12	131000460	AL563727	57634	12q24.33	Hs.699245	19	nucleotide binding DNA binding helicase activity ATP binding nucleus nucleolus chromatin modification hydrolase activity NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation
226268_at	-0.534	6.008	-2.636	1.855e-02	0.215	-3.285	RAB21	RAB21, member RAS oncogene family	12	70434924	AI309554	23011	12q21.1	Hs.524590	12	Golgi membrane nucleotide binding protein binding GTP binding endosome endoplasmic reticulum Golgi apparatus small GTPase mediated signal transduction protein transport membrane cytoplasmic vesicle membrane cytoplasmic vesicle early endosome membrane
200795_at	0.344	10.572	2.635	1.860e-02	0.215	-3.287	SPARCL1	SPARC-like 1 (hevin)	4	-88613511	NM_004684	8404	4q22.1	Hs.62886	14	calcium ion binding extracellular region proteinaceous extracellular matrix signal transduction synapse
219297_at	-0.268	6.172	-2.634	1.861e-02	0.215	-3.287	WDR44	WD repeat domain 44	X	117364069	NM_019045	54521	Xq24	Hs.98510	16	cytoplasm endosome Golgi apparatus cytosol endosome membrane membrane perinuclear region of cytoplasm
211538_s_at	-1.111	9.831	-2.634	1.861e-02	0.215	-3.288	HSPA2	heat shock 70kDa protein 2	14	64076938	U56725	3306	14q24.1	Hs.719230	42	nucleotide binding ATP binding mitochondrion response to unfolded protein male meiosis spermatid development cell surface unfolded protein binding	MAPK signaling pathway Endocytosis Antigen processing and presentation
221888_at	0.244	5.934	2.634	1.862e-02	0.215	-3.288	CC2D1A	coiled-coil and C2 domain containing 1A	19	13877955	AW183030	54862	19p13.12	Hs.269592	18	DNA binding signal transducer activity nucleus nucleolus cytoplasm positive regulation of I-kappaB kinase/NF-kappaB cascade regulation of transcription
204819_at	0.296	5.282	2.634	1.862e-02	0.215	-3.288	FGD1	FYVE, RhoGEF and PH domain containing 1	X	-54488611	NM_004463	2245	Xp11.21	Hs.709201	23	ruffle guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular nucleus cytoplasm Golgi apparatus cytoskeleton plasma membrane signal transduction multicellular organismal development zinc ion binding regulation of cell shape organ morphogenesis lamellipodium actin cytoskeleton organization small GTPase binding regulation of Rho protein signal transduction regulation of Cdc42 GTPase activity filopodium assembly metal ion binding	Regulation of actin cytoskeleton
227687_at	-0.406	5.901	-2.633	1.864e-02	0.215	-3.289	HYLS1	hydrolethalus syndrome 1	11	125258718, 125262164	AL523264	219844	11q24.2	Hs.585071	7	cytoplasm
237759_at	0.279	5.367	2.633	1.865e-02	0.215	-3.289	CD48	CD48 molecule	1	-158915159	AI378026	962	1q21.3-q22	Hs.243564	35	protein binding plasma membrane integral to plasma membrane defense response anchored to membrane membrane raft	Natural killer cell mediated cytotoxicity
201968_s_at	-0.401	12.264	-2.633	1.865e-02	0.215	-3.290	PGM1	phosphoglucomutase 1	1	63831534	NM_002633	5236	1p31	Hs.1869	22	magnesium ion binding phosphoglucomutase activity phosphoglucomutase activity cytoplasm cytosol carbohydrate metabolic process glucose metabolic process isomerase activity	Glycolysis / Gluconeogenesis Pentose phosphate pathway Galactose metabolism Starch and sucrose metabolism Amino sugar and nucleotide sugar metabolism Streptomycin biosynthesis Metabolic pathways
204777_s_at	0.244	5.155	2.633	1.867e-02	0.215	-3.290	MAL	mal, T-cell differentiation protein	2	95055205	NM_002371	4118	2cen-q13	Hs.80395	28	membrane raft polarization endosome endoplasmic reticulum integral to plasma membrane induction of apoptosis central nervous system development lipid binding channel activity membrane apical plasma membrane apoptotic protease activator activity structural constituent of myelin sheath cell differentiation myelination myelination membrane raft apical protein localization
1564190_x_at	0.318	4.303	2.633	1.867e-02	0.215	-3.291	ZNF519	zinc finger protein 519	18	-14094723	AK096748	162655	18p11.21	Hs.352635	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
203923_s_at	0.446	5.501	2.632	1.867e-02	0.215	-3.291	CYBB	cytochrome b-245, beta polypeptide	X	37524213	NM_000397	1536	Xp21.1	Hs.292356	96	voltage-gated ion channel activity protein binding cytoplasm mitochondrion plasma membrane ion transport inflammatory response electron carrier activity superoxide-generating NADPH oxidase activity superoxide-generating NADPH oxidase activity oxidoreductase activity heme binding electron transport chain superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex innate immune response innate immune response respiratory burst respiratory burst metal ion binding protein heterodimerization activity FAD binding	Leukocyte transendothelial migration
1558675_s_at	-0.362	6.888	-2.632	1.868e-02	0.215	-3.291	SDCCAG1	serologically defined colon cancer antigen 1	14	-49320281	AV724508	9147	14q22	Hs.655964	8	nucleus cytoplasm
212514_x_at	-0.519	6.111	-2.632	1.869e-02	0.215	-3.291	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	X	41077594	R60068	1654	Xp11.3-p11.23	Hs.719127	34	nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus cytoplasm plasma membrane nuclear speck hydrolase activity interspecies interaction between organisms	RIG-I-like receptor signaling pathway
226995_at	0.392	4.592	2.632	1.869e-02	0.215	-3.291	LOC642852	hypothetical LOC642852	21	45532394	AV705934	642852	21q22.3	Hs.11637 Hs.676029 Hs.710382	2
202050_s_at	-0.260	7.009	-2.632	1.869e-02	0.215	-3.291	ZMYM4	zinc finger, MYM-type 4	1	35507154	AI650586	9202	1p32-p34	Hs.269211	7	DNA binding nucleus multicellular organismal development zinc ion binding metal ion binding
225994_at	-0.646	6.347	-2.632	1.869e-02	0.215	-3.292	CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	14	91658081	AK023583	53981	14q31.1	Hs.657632	24	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus hydrolase activity
211672_s_at	-0.395	6.332	-2.632	1.869e-02	0.215	-3.292	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	3	9809226	AF019888	10093	3p25.3	Hs.323342	16	cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
59625_at	-0.209	7.889	-2.632	1.870e-02	0.215	-3.292	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	16	65765370	AI912351	8996	16q21-q23	Hs.513667	22	RNA binding intracellular nucleus nucleolus cytoplasm cytosol mRNA processing anti-apoptosis RNA splicing identical protein binding regulation of apoptosis
205099_s_at	0.348	4.670	2.631	1.871e-02	0.215	-3.293	CCR1	chemokine (C-C motif) receptor 1	3	-46218203	NM_001295	1230	3p21	Hs.301921	71	receptor activity G-protein coupled receptor activity protein binding plasma membrane plasma membrane integral to plasma membrane chemotaxis inflammatory response immune response cell adhesion G-protein signaling, coupled to cyclic nucleotide second messenger elevation of cytosolic calcium ion concentration cell-cell signaling C-C chemokine receptor activity cytokine-mediated signaling pathway	Cytokine-cytokine receptor interaction Chemokine signaling pathway
239640_at	0.201	4.960	2.631	1.871e-02	0.215	-3.293	LOC401320	hypothetical LOC401320	7		AI221073	401320	7p15.1	Hs.561708	2
224113_at	0.291	5.627	2.631	1.875e-02	0.216	-3.294	CARD14	caspase recruitment domain family, member 14	17	75766875, 75776193	BC001326	79092	17q25	Hs.675480 Hs.696253	7	positive regulation of protein amino acid phosphorylation protein binding intracellular cytoplasm plasma membrane activation of NF-kappaB-inducing kinase activity regulation of apoptosis CARD domain binding
202208_s_at	0.347	5.635	2.630	1.876e-02	0.216	-3.295	ARL4C	ADP-ribosylation factor-like 4C	2	-235066424	BC001051	10123	2q37.1	Hs.111554 Hs.719190	7	nucleotide binding GTPase activity GTP binding intracellular nucleus small GTPase mediated signal transduction
204882_at	0.309	5.480	2.630	1.877e-02	0.216	-3.295	ARHGAP25	Rho GTPase activating protein 25	2	68815471, 68855436	NM_014882	9938	2p13.3	Hs.531807	4	GTPase activator activity intracellular signal transduction
224804_s_at	0.242	7.498	2.629	1.879e-02	0.216	-3.296	C15orf17	chromosome 15 open reading frame 17	15	-72979380	AU152410	57184	15q24.1	Hs.367690	4
207342_at	0.249	3.480	2.629	1.882e-02	0.216	-3.298	CNGB1	cyclic nucleotide gated channel beta 1	16	-56546080, -56473744	NM_001297	1258	16q13	Hs.147062	16	nucleotide binding ion channel activity intracellular cAMP activated cation channel activity membrane fraction ion transport phototransduction membrane integral to membrane intracellular cyclic nucleotide activated cation channel complex cAMP binding photoreceptor cell maintenance	Olfactory transduction
222021_x_at	0.269	10.254	2.629	1.882e-02	0.216	-3.298	SDHALP1	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1	3	-197171189	AI348006	255812	3q29	Hs.566872 Hs.596261	2
221487_s_at	-0.720	7.202	-2.628	1.885e-02	0.216	-3.299	ENSA	endosulfine alpha	1	-148866145, -148862377, -148862377, -148861222, -148861222	AF157510	2029	1q21.3	Hs.632456	15	receptor binding cytoplasm transport response to nutrient ion channel inhibitor activity
211658_at	0.261	8.155	2.628	1.886e-02	0.216	-3.299	PRDX2	peroxiredoxin 2	19	-12772426, -12768633	L19185	7001	19p13.2	Hs.432121	52	cytoplasm anti-apoptosis response to oxidative stress response to oxidative stress thioredoxin peroxidase activity oxidoreductase activity regulation of apoptosis cell redox homeostasis oxidation reduction
227777_at	-0.426	6.772	-2.628	1.886e-02	0.216	-3.300	C10orf18	chromosome 10 open reading frame 18	10	5766806	BF223040	54906	10p15.1	Hs.699500	4
1556095_at	-1.235	3.986	-2.627	1.886e-02	0.216	-3.300	UNC13C	unc-13 homolog C (C. elegans)	15	52092392	AL834407	440279	15q21.3	Hs.657273	4	cytoplasm plasma membrane exocytosis intracellular signaling cascade synaptic transmission zinc ion binding diacylglycerol binding cell junction synapse metal ion binding
219949_at	-0.502	10.555	-2.627	1.887e-02	0.216	-3.300	LRRC2	leucine rich repeat containing 2	3	-46531881, -46531881	NM_024512	79442	3p21.31	Hs.657345	7	protein binding
1558345_a_at	0.268	5.690	2.627	1.887e-02	0.216	-3.300	LOC439911	hypothetical gene supported by NM_194304	10		BI715235	439911	10q11.21
217383_at	-0.445	5.805	-2.627	1.887e-02	0.216	-3.300	PGK1	phosphoglycerate kinase 1	X	77246321	S81916	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
231106_at	-0.276	6.610	-2.627	1.888e-02	0.216	-3.301	BMS1P5	BMS1 pseudogene 5	10	-46157620	AI684591	399761	10q11.22	Hs.314437 Hs.711074	2
209785_s_at	-0.458	9.028	-2.627	1.889e-02	0.217	-3.301	PLA2G4C	phospholipase A2, group IVC (cytosolic, calcium-independent)	19	-53242912	AF065214	8605	19q13.3	Hs.631562	22	phospholipid binding cytosol inflammatory response intracellular signaling cascade parturition metabolic process membrane lipid catabolic process hydrolase activity arachidonic acid metabolic process glycerophospholipid catabolic process calcium-independent phospholipase A2 activity
228789_at	-0.267	3.020	-2.626	1.891e-02	0.217	-3.302	MTMR6	myotubularin related protein 6	13	-24718340	AI290971	9107	13q12	Hs.643702	17	protein serine/threonine phosphatase activity protein tyrosine phosphatase activity cellular_component nucleus nuclear envelope cytoplasm protein amino acid dephosphorylation calcium-activated potassium channel activity hydrolase activity phosphatase activity	Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways
208495_at	0.184	2.803	2.626	1.892e-02	0.217	-3.303	TLX3	T-cell leukemia homeobox 3	5	170668892	NM_021025	30012	5q35.1	Hs.249125	19	neuron migration regulation of respiratory gaseous exchange by neurological system process transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development central nervous system development respiratory gaseous exchange sequence-specific DNA binding negative regulation of neuron differentiation neuron fate specification
233119_at	0.320	4.943	2.626	1.892e-02	0.217	-3.303	PRR5L	proline rich 5 like	11	36274300, 36354110, 36379122	AV732741	79899	11p13-p12	Hs.19987	4
213983_s_at	-0.358	4.235	-2.626	1.893e-02	0.217	-3.303	PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	4	-39575985, -39500877, -39500877	AW991219	23244	4p14	Hs.331431	11	chromatin nucleus cell cycle mitosis identical protein binding cell division
227105_at	-0.597	5.842	-2.625	1.895e-02	0.217	-3.304	CSPP1	centrosome and spindle pole associated protein 1	8	68139156	AI400587	79848	8q13.1-q13.2	Hs.370147	6	centrosome microtubule
207718_x_at	0.281	4.390	2.625	1.896e-02	0.217	-3.304	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	19	-46073183	NM_000764	1549	19q13.2	Hs.250615	13	endoplasmic reticulum microsome electron carrier activity membrane oxygen binding heme binding metal ion binding oxidation reduction aromatase activity	Caffeine metabolism Retinol metabolism Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
201831_s_at	-0.619	8.187	-2.625	1.897e-02	0.217	-3.305	USO1	USO1 homolog, vesicle docking protein (yeast)	4	76868852	BE875592	8615	4q21.1	Hs.292689	34	Golgi membrane protein binding cytoplasm microsome Golgi apparatus cytosol intracellular protein transport protein transporter activity membrane vesicle-mediated transport vesicle fusion with Golgi apparatus perinuclear region of cytoplasm
213014_at	0.260	4.667	2.625	1.897e-02	0.217	-3.305	MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	11	45863777	BG222394	9479	11p12-p11.2	Hs.234249	46	protein kinase inhibitor activity MAP-kinase scaffold activity protein binding nucleus cytoplasm vesicle-mediated transport kinesin binding protein kinase binding regulation of JNK cascade perinuclear region of cytoplasm	MAPK signaling pathway
243428_at	0.316	4.494	2.625	1.898e-02	0.217	-3.305	KCNQ1OT1	KCNQ1 overlapping transcript 1 (non-protein coding)	11	-2618343	AW613101	10984	11p15	Hs.647285 Hs.655148	25
225814_at	-0.351	8.189	-2.624	1.900e-02	0.217	-3.306	XRN1	5'-3' exoribonuclease 1	3	-143508138	BG534738	54464	3q23	Hs.435103	12	DNA binding RNA binding protein binding intracellular cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5'-3' exonuclease activity hydrolase activity	RNA degradation
211875_x_at	0.208	4.556	2.624	1.900e-02	0.217	-3.306	PCDHGA10	protocadherin gamma subfamily A, 10	5	140772926, 140772926	AF152503	56106	5q31	Hs.368160	6	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
1556180_at	0.349	6.282	2.623	1.903e-02	0.218	-3.308	LOC729678	hypothetical protein LOC729678	5	180189564	BE646146	729678	5q35.3	Hs.348292 Hs.655606	3
207209_at	-0.249	4.464	-2.623	1.905e-02	0.218	-3.308	CETN1	centrin, EF-hand protein, 1	18	570368	NM_004066	1068	18p11.32	Hs.122511	8	calcium ion binding centrosome spindle pole body cytoskeleton cell cycle mitosis mitotic centrosome separation G-protein beta/gamma-subunit binding photoreceptor connecting cilium cellular response to heat cell division
230061_at	0.542	5.489	2.623	1.905e-02	0.218	-3.309	TM4SF18	transmembrane 4 L six family member 18	3	-150521544	AW338625	116441	3q25.1	Hs.22026	3	membrane integral to membrane
210094_s_at	-0.294	7.207	-2.622	1.906e-02	0.218	-3.309	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AF196186	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
1570035_at	0.327	3.708	2.622	1.908e-02	0.218	-3.310	TBC1D10A	TBC1 domain family, member 10A	22	-29017978	BC007908	83874	22q12.1-qter	Hs.655273	13	Rab GTPase activator activity protein binding intracellular microvillus biological_process PDZ domain binding regulation of Rab GTPase activity
204765_at	0.260	4.799	2.622	1.909e-02	0.218	-3.311	ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5	7	143683421	NM_005435	7984	7q33-q35	Hs.334 Hs.534621	12	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding GTP binding intracellular intracellular signaling cascade regulation of Rho protein signal transduction
216053_x_at	0.239	4.612	2.621	1.910e-02	0.218	-3.311	FAM182A	family with sequence similarity 182, member A	20	25983249	AI143919	284800	20p11.1	Hs.662381	3
244730_x_at	0.299	6.783	2.621	1.911e-02	0.218	-3.312	LOC100129195	hypothetical protein LOC100129195	6		BF671528	100129195	6p22.1	Hs.659413
202190_at	0.509	5.919	2.621	1.912e-02	0.218	-3.312	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	20	54400833, 54400980, 54401113	NM_001324	1477	20q13.2	Hs.172865	19	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA polyadenylation mRNA cleavage
218458_at	-0.479	5.670	-2.620	1.914e-02	0.218	-3.313	GMCL1	germ cell-less homolog 1 (Drosophila)	2	69910321	NM_022471	64395	2p13.3	Hs.293971	7	protein binding nucleus nuclear envelope multicellular organismal development spermatogenesis nuclear matrix cell differentiation regulation of transcription
212688_at	-0.370	7.969	-2.620	1.915e-02	0.218	-3.313	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	3	-139856920	BC003393	5291	3q22.3	Hs.239818	58	nucleotide binding activation of MAPK activity regulation of cell-matrix adhesion inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex cellular calcium ion homeostasis chemotaxis homophilic cell adhesion signal transduction G-protein coupled receptor protein signaling pathway 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor platelet activation embryonic cleavage insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
212430_at	-0.543	7.854	-2.619	1.918e-02	0.218	-3.315	RBM38	RNA binding motif protein 38	20	55399869	AL109955	55544	20q13.31	Hs.236361	6	nucleotide binding mRNA 3'-UTR binding nucleus cytoplasm cytosol mRNA processing DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle regulation of RNA splicing protein stabilization
204740_at	-0.322	6.533	-2.619	1.918e-02	0.218	-3.315	CNKSR1	connector enhancer of kinase suppressor of Ras 1	1	26376567, 26376568	NM_006314	10256	1p36.11	Hs.16232	17	cytoplasm plasma membrane cell-cell junction cell cortex transmembrane receptor protein tyrosine kinase signaling pathway Rho protein signal transduction protein binding, bridging
209901_x_at	0.304	5.638	2.618	1.922e-02	0.219	-3.317	AIF1	allograft inflammatory factor 1	6	31690972, 31691011, 31691767, 3029118, 3029157, 3029913, 2830581, 2830620, 2831376	U19713	199	6p21.3	Hs.76364	38	calcium ion binding nucleus response to stress inflammatory response cell cycle arrest negative regulation of cell proliferation
218031_s_at	-0.432	8.265	-2.618	1.923e-02	0.219	-3.317	FOXN3	forkhead box N3	14	-88692268, -88692268	NM_018589	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
200740_s_at	-0.240	9.325	-2.618	1.924e-02	0.219	-3.318	SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	21	-45049959	NM_006936	6612	21q22.3	Hs.474005	40	kinetochore protein binding cytoplasm protein sumoylation modification-dependent protein catabolic process
1555783_x_at	0.239	5.164	2.617	1.927e-02	0.219	-3.319	PQLC2	PQ loop repeat containing 2	1	19511326	BC015324	54896	1p36.13	Hs.647620	5	membrane integral to membrane
228845_at	0.205	6.076	2.617	1.928e-02	0.219	-3.320	PLBD2	phospholipase B domain containing 2	12	112280753	AW451356	196463	12q24.13	Hs.115896	4	lipid catabolic process hydrolase activity lysosomal lumen
224964_s_at	0.481	5.830	2.616	1.932e-02	0.219	-3.321	GNG2	guanine nucleotide binding protein (G protein), gamma 2	14	51396799	AK026424	54331	14q21	Hs.187772 Hs.709082 Hs.713545	31	signal transducer activity Golgi apparatus heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway cell proliferation hormone-mediated signaling	Chemokine signaling pathway
225208_s_at	-0.250	7.809	-2.615	1.936e-02	0.220	-3.323	FAM103A1	family with sequence similarity 103, member A1	15	81445998	AW575350	83640	15q25.2	Hs.80624	3
212835_at	-0.535	6.466	-2.614	1.937e-02	0.220	-3.324	FAM175B	family with sequence similarity 175, member B	10	126480343	AA777641	23172	10q26.13	Hs.280695	10	protein binding polyubiquitin binding BRISC complex
221766_s_at	-0.358	6.569	-2.614	1.937e-02	0.220	-3.324	FAM46A	family with sequence similarity 46, member A	6	-82512165	AW246673	55603	6q14	Hs.10784	11
200901_s_at	-0.268	7.125	-2.614	1.937e-02	0.220	-3.324	M6PR	mannose-6-phosphate receptor (cation dependent)	12	-8984230	NM_002355	4074	12p13	Hs.134084	31	transmembrane receptor activity protein binding mannose binding lysosome late endosome integral to plasma membrane transport receptor-mediated endocytosis endosome to lysosome transport cell surface mannose transmembrane transporter activity mannose transport membrane	Lysosome
220253_s_at	-0.694	5.164	-2.614	1.937e-02	0.220	-3.324	LRP12	low density lipoprotein-related protein 12	8	-105570642	NM_013437	29967	8q22.2-q23.1	Hs.600630	8	receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth
219133_at	0.265	8.022	2.614	1.938e-02	0.220	-3.324	OXSM	3-oxoacyl-ACP synthase, mitochondrial	3	25806566	NM_017897	54995	3p24.2	Hs.55781 Hs.719350	7	3-oxoacyl-[acyl-carrier-protein] synthase activity mitochondrion acyl-CoA metabolic process acyltransferase activity transferase activity short-chain fatty acid biosynthetic process medium-chain fatty acid biosynthetic process	Fatty acid biosynthesis Metabolic pathways
223136_at	0.556	7.015	2.614	1.939e-02	0.220	-3.325	AIG1	androgen-induced 1	6	143423715	AF151861	51390	6q24.2	Hs.567501	8	membrane integral to membrane
200769_s_at	-0.435	6.068	-2.613	1.940e-02	0.220	-3.325	MAT2A	methionine adenosyltransferase II, alpha	2	85619798	NM_005911	4144	2p11.2	Hs.516157	18	nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP	Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways
209879_at	0.325	5.698	2.613	1.942e-02	0.220	-3.326	SELPLG	selectin P ligand	12	-107539808	AI741056	6404	12q24	Hs.591014	100	receptor binding membrane fraction integral to plasma membrane cell adhesion bacterial binding membrane leukocyte tethering or rolling	Cell adhesion molecules (CAMs)
208860_s_at	-0.397	7.456	-2.613	1.943e-02	0.220	-3.326	ATRX	alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)	X	-76647011	U09820	546	Xq13.1-q21.1	Hs.533526 Hs.645562 Hs.653797	66	nucleotide binding DNA binding DNA helicase activity protein binding ATP binding nucleus nuclear heterochromatin DNA repair DNA methylation DNA recombination regulation of transcription, DNA-dependent response to DNA damage stimulus zinc ion binding hydrolase activity metal ion binding
213159_at	0.267	5.515	2.613	1.943e-02	0.220	-3.327	PCNX	pecanex homolog (Drosophila)	14	70443874	AB018348	22990	14q24.2	Hs.446559	10	membrane integral to membrane
226017_at	0.320	6.648	2.612	1.944e-02	0.220	-3.327	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	3	32408166	AI708432	112616	3p22.3	Hs.440494	4	cytokine activity extracellular space chemotaxis membrane integral to membrane
236320_at	0.254	3.883	2.612	1.944e-02	0.220	-3.327	CCDC17	coiled-coil domain containing 17	1	-45858302	AA010540	149483	1p34.1	Hs.18912	3
232067_at	0.321	3.182	2.612	1.945e-02	0.220	-3.328	C6orf168	chromosome 6 open reading frame 168	6	-99827513	BC004869	84553	6q16.2	Hs.573245	5	mitochondrial outer membrane protein targeting to mitochondrion
227442_at	0.244	6.930	2.611	1.948e-02	0.220	-3.329	COX18	COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)	4	-74139279	BG283902	285521	4q13.3	Hs.356697	5	mitochondrion mitochondrial inner membrane respiratory chain complex IV assembly protein transporter activity membrane integral to membrane integral to mitochondrial inner membrane protein insertion into mitochondrial membrane
235252_at	-0.436	7.537	-2.611	1.949e-02	0.220	-3.329	KSR1	kinase suppressor of ras 1	17	22823162	AI090141	8844	17q11.1-q11.2	Hs.133534	15	protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding intracellular cytoplasm protein amino acid phosphorylation intracellular signaling cascade Ras protein signal transduction zinc ion binding membrane diacylglycerol binding metal ion binding
226331_at	-0.237	7.064	-2.611	1.949e-02	0.220	-3.329	BBX	bobby sox homolog (Drosophila)	3	108724472	BF508813	56987	3q13.1	Hs.124366	11	DNA binding nucleus regulation of transcription
219365_s_at	0.278	5.565	2.611	1.949e-02	0.220	-3.329	CAMKV	CaM kinase-like vesicle-associated	3	-49870425	NM_024046	79012	3p21.31	Hs.145156	10	protein serine/threonine kinase activity ATP binding plasma membrane protein amino acid phosphorylation cytoplasmic vesicle
203555_at	0.193	6.307	2.611	1.950e-02	0.220	-3.330	PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	2	130830049	NM_014369	26469	2q21.1	Hs.516390 Hs.591549	16	non-membrane spanning protein tyrosine phosphatase activity nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity
213870_at	0.294	5.566	2.611	1.951e-02	0.220	-3.330	COL11A2	collagen, type XI, alpha 2	6	-33262201, -33238446, -4534386, -4510632, -4340391, -4316638	AL031228	1302	6p21.3	Hs.390171	39	extracellular region collagen collagen type XI cell adhesion sensory perception of sound extracellular matrix structural constituent conferring tensile strength collagen fibril organization protein binding, bridging cartilage development soft palate development	Focal adhesion ECM-receptor interaction
34260_at	0.241	6.099	2.610	1.952e-02	0.220	-3.331	TELO2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	16	1483352	AB014583	9894	16p13.3	Hs.271044	13	chromosome, telomeric region protein binding intracellular nucleus chromosome cytoplasm membrane
204075_s_at	-0.400	6.299	-2.610	1.953e-02	0.220	-3.331	KIAA0562	KIAA0562	1	-3721203	NM_014704	9731	1p36.32	Hs.133089 Hs.509017	6	binding
203804_s_at	-0.265	8.942	-2.610	1.953e-02	0.220	-3.331	LUC7L3	LUC7-like 3 (S. cerevisiae)	17	46151975	NM_006107	51747	17q21.33	Hs.130293	15	DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck
216064_s_at	-0.515	5.354	-2.610	1.953e-02	0.220	-3.331	AGA	aspartylglucosaminidase	4	-178588917	W27131	175	4q32-q33	Hs.207776	36	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity lysosome protein deglycosylation hydrolase activity protein maturation	Other glycan degradation Lysosome
209109_s_at	0.320	5.904	2.610	1.954e-02	0.220	-3.332	TSPAN6	tetraspanin 6	X	-99770450	U84895	7105	Xq22	Hs.43233	10	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
201663_s_at	-0.464	4.686	-2.610	1.954e-02	0.220	-3.332	SMC4	structural maintenance of chromosomes 4	3	161600123, 161601040	NM_005496	10051	3q26.1	Hs.58992	14	nucleotide binding condensin complex condensin complex protein binding ATP binding nucleus chromosome cytoplasm cell cycle mitotic chromosome condensation protein heterodimerization activity cell division
230122_at	0.305	3.275	2.610	1.955e-02	0.220	-3.332	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10	21863107, 21863579	BE219716	8028	10p12	Hs.30385	19	transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding
205795_at	0.272	3.553	2.610	1.955e-02	0.220	-3.332	NRXN3	neurexin 3	14	77939845, 78815406	NM_004796	9369	14q31	Hs.368307	20	receptor activity calcium ion binding protein binding integral to plasma membrane cell adhesion axon guidance membrane integral to membrane	Cell adhesion molecules (CAMs)
223436_s_at	0.638	8.773	2.610	1.955e-02	0.220	-3.332	TRPT1	tRNA phosphotransferase 1	11	-63747847, -63747847	BC005133	83707	11q13.1	Hs.326586	6	tRNA 2'-phosphotransferase activity tRNA splicing, via endonucleolytic cleavage and ligation transferase activity, transferring phosphorus-containing groups
212343_at	-0.386	6.766	-2.609	1.956e-02	0.220	-3.333	YIPF6	Yip1 domain family, member 6	X	67635610	AL117461	286451	Xq12	Hs.700646 Hs.82719	10	endoplasmic reticulum membrane integral to membrane
202829_s_at	-0.315	7.722	-2.609	1.959e-02	0.221	-3.334	VAMP7	vesicle-associated membrane protein 7	X, Y	154764140, 57623340	NM_005638	6845	Xq28 Yq12	Hs.24167	38	protein binding protein binding lysosomal membrane endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ER to Golgi vesicle-mediated transport vesicle fusion phagocytosis, engulfment endosome to lysosome transport protein transport membrane integral to membrane calcium ion-dependent exocytosis SNARE complex cytoplasmic vesicle late endosome membrane eosinophil degranulation neutrophil degranulation apical part of cell phagocytic vesicle	SNARE interactions in vesicular transport
213298_at	-0.590	5.938	-2.608	1.959e-02	0.221	-3.334	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	19	3310615, 3317572	X12492	4782	19p13.3	Hs.170131	23	negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus DNA replication regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter
228059_x_at	0.273	8.686	2.608	1.960e-02	0.221	-3.334	MRPS22	mitochondrial ribosomal protein S22	3	140545550	BF594653	56945	3q23	Hs.75724	13	molecular_function structural constituent of ribosome protein binding mitochondrion mitochondrial small ribosomal subunit ribosome biological_process
208606_s_at	-0.322	4.531	-2.608	1.961e-02	0.221	-3.335	WNT4	wingless-type MMTV integration site family, member 4	1	-22316384	NM_030761	54361	1p36.23-p35.1	Hs.25766	35	signal transducer activity extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway cell-cell signaling multicellular organismal development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
210610_at	0.213	5.710	2.608	1.963e-02	0.221	-3.336	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	M69176	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
223989_s_at	0.346	6.989	2.607	1.964e-02	0.221	-3.336	REXO2	REX2, RNA exonuclease 2 homolog (S. cerevisiae)	11	113815317	BC003502	25996	11q23.1-q23.2	Hs.677190 Hs.7527	15	nucleic acid binding intracellular nucleus mitochondrion nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3'-5' exonuclease activity nucleotide metabolic process hydrolase activity manganese ion binding
235035_at	-0.253	5.453	-2.607	1.964e-02	0.221	-3.336	SLC35E1	solute carrier family 35, member E1	19	-16521647	BF342223	79939	19p13.11	Hs.620596	5	transport membrane integral to membrane
211896_s_at	0.582	9.506	2.607	1.964e-02	0.221	-3.336	DCN	decorin	12	-90063165, -90063165, -90063165	AF138302	1634	12q21.33	Hs.718429	104	protein binding glycosaminoglycan binding extracellular region proteinaceous extracellular matrix organ morphogenesis peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix binding	TGF-beta signaling pathway
207761_s_at	-0.807	9.495	-2.607	1.964e-02	0.221	-3.336	METTL7A	methyltransferase like 7A	12	49604800	NM_014033	25840	12q13.12	Hs.711113 Hs.716437	6	metabolic process methyltransferase activity transferase activity
227406_at	0.368	6.757	2.607	1.965e-02	0.221	-3.337	LOC100129387	hypothetical LOC100129387	15	48433662	AI286203	100129387	15q21.2	Hs.659360	1
201869_s_at	0.257	5.099	2.607	1.966e-02	0.221	-3.337	TBL1X	transducin (beta)-like 1X-linked	X	9391334, 9393200	BF593932	6907	Xp22.3	Hs.495656	16	nucleus signal transduction visual perception sensory perception of sound modification-dependent protein catabolic process regulation of transcription	Wnt signaling pathway
212097_at	0.535	9.848	2.607	1.967e-02	0.221	-3.338	CAV1	caveolin 1, caveolae protein, 22kDa	7	115952074	AU147399	857	7q31.1	Hs.74034	318	Golgi membrane Golgi membrane inactivation of MAPK activity vasculogenesis response to hypoxia negative regulation of endothelial cell proliferation intracellular endoplasmic reticulum Golgi apparatus lipid particle plasma membrane caveola triglyceride metabolic process calcium ion transport endocytosis regulation of smooth muscle contraction skeletal muscle tissue development protein localization positive regulation of calcium ion transport into cytosol cholesterol binding integral to membrane vesicle organization peptidase activator activity regulation of fatty acid metabolic process lipid storage regulation of blood coagulation cholesterol transport negative regulation of epithelial cell differentiation mammary gland development maintenance of protein location in cell response to progesterone stimulus protein complex scaffold nitric oxide homeostasis cholesterol homeostasis negative regulation of MAPKKK cascade response to estrogen stimulus interspecies interaction between organisms negative regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction negative regulation of vasodilation negative regulation of JAK-STAT cascade perinuclear region of cytoplasm positive regulation of metalloenzyme activity nitric-oxide synthase binding protein homooligomerization cytosolic calcium ion homeostasis response to calcium ion membrane depolarization regulation of peptidase activity mammary gland involution	Focal adhesion
222597_at	-0.530	4.963	-2.605	1.971e-02	0.221	-3.340	SNAP29	synaptosomal-associated protein, 29kDa	22	19543291	AI346639	9342	22q11.21	Hs.108002 Hs.701035	19	SNAP receptor activity cytoplasm plasma membrane exocytosis vesicle targeting membrane fusion protein transport synaptosome cell junction synapse	SNARE interactions in vesicular transport
218097_s_at	0.226	9.332	2.605	1.971e-02	0.221	-3.340	CUEDC2	CUE domain containing 2	10	-104172991	NM_024040	79004	10q24.32	Hs.500874	6	protein binding nucleus cytoplasm modification-dependent protein catabolic process
222993_at	0.243	9.203	2.605	1.973e-02	0.222	-3.340	MRPL37	mitochondrial ribosomal protein L37	1	54438427	AF325707	51253	1p32.1	Hs.584908	8	structural constituent of ribosome mitochondrion mitochondrial ribosome ribosome translation translation regulator activity
201074_at	-0.349	6.544	-2.605	1.973e-02	0.222	-3.341	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	3	-47602381	AA593983	6599	3p23-p21	Hs.476179	39	chromatin DNA binding chromatin binding transcription coactivator activity intracellular nucleus nucleoplasm chromatin assembly or disassembly chromatin remodeling regulation of transcription from RNA polymerase II promoter protein C-terminus binding organ morphogenesis SWI/SNF complex regulation of transcription positive regulation of transcription, DNA-dependent protein N-terminus binding
229438_at	0.215	5.470	2.604	1.976e-02	0.222	-3.342	LOC100132244	hypothetical protein LOC100132244	7		AK026140	100132244	7p22.3	Hs.632006
201763_s_at	0.171	6.600	2.604	1.976e-02	0.222	-3.342	DAXX	death-domain associated protein	6	-33394312, -4666475, -4472530	NM_001350	1616	6p21.3	Hs.336916	99	cytokinesis after mitosis heterochromatin receptor signaling protein activity nucleus cytoplasm apoptosis activation of JUN kinase activity induction of apoptosis via death domain receptors transcription repressor activity PML body androgen receptor signaling pathway heat shock protein binding identical protein binding interspecies interaction between organisms regulation of transcription negative regulation of transcription, DNA-dependent protein N-terminus binding androgen receptor binding	MAPK signaling pathway Amyotrophic lateral sclerosis (ALS)
214683_s_at	-0.510	8.242	-2.604	1.977e-02	0.222	-3.342	CLK1	CDC-like kinase 1	2	-201425977, -201425977	AI251890	1195	2q33	Hs.433732	25	nucleotide binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding nucleus protein amino acid phosphorylation cell proliferation transferase activity
210635_s_at	-0.465	5.033	-2.604	1.979e-02	0.222	-3.343	KLHL20	kelch-like 20 (Drosophila)	1	171950702	BC005253	27252	1q24.1-q24.3	Hs.495035	10	actin binding protein binding cytoskeleton organization cell surface actin cytoskeleton modification-dependent protein catabolic process
221474_at	0.307	10.442	2.603	1.979e-02	0.222	-3.343	MYL12B	myosin, light chain 12B, regulatory	18	3252110, 3252610, 3252716	U26162	103910	18p11.31	Hs.190086 Hs.464472	7	motor activity calcium ion binding myosin complex apical part of cell	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
235126_at	0.464	5.654	2.603	1.980e-02	0.222	-3.343	LQK1	hypothetical LOC642946	1	-211096569	N51468	642946	1q32.3	Hs.552649	1
223043_at	-0.265	10.426	-2.603	1.980e-02	0.222	-3.343	TMEM85	transmembrane protein 85	15	32304536	AF151018	51234	15q14	Hs.250905	6	apoptosis membrane integral to membrane
210942_s_at	-1.251	4.696	-2.603	1.981e-02	0.222	-3.344	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	3	99934261	AB022918	10402	3q12.1	Hs.148716	5	Golgi apparatus amino sugar metabolic process protein amino acid glycosylation glycolipid metabolic process sialyltransferase activity protein lipoylation membrane integral to membrane integral to Golgi membrane	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
203980_at	0.930	9.897	2.603	1.981e-02	0.222	-3.344	FABP4	fatty acid binding protein 4, adipocyte	8	-82553286	NM_001442	2167	8q21	Hs.391561	44	cytokine production transporter activity fatty acid binding protein binding soluble fraction nucleus cytoplasm cytosol negative regulation of protein kinase activity fatty acid metabolic process transport positive regulation of cell proliferation negative regulation of transcription transcription repressor activity response to drug cholesterol homeostasis positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation response to glucocorticoid stimulus	PPAR signaling pathway
224695_at	-0.301	7.231	-2.603	1.982e-02	0.222	-3.345	C2orf29	chromosome 2 open reading frame 29	2	101235776	AK024221	55571	2q11.2	Hs.715598	5	molecular_function cellular_component cell proliferation
225723_at	0.385	6.572	2.603	1.982e-02	0.222	-3.345	C6orf129	chromosome 6 open reading frame 129	6	-37558674	BE794699	154467	6p21.2	Hs.284207	3	membrane integral to membrane
212946_at	-0.340	9.150	-2.602	1.983e-02	0.222	-3.345	KIAA0564	KIAA0564	13	-41191472, -41038960	AK025432	23078	13q14.11	Hs.368282	4	nucleotide binding ATP binding extracellular region ATPase activity
206101_at	0.591	7.260	2.602	1.984e-02	0.222	-3.345	ECM2	extracellular matrix protein 2, female organ and adipocyte specific	9	-94297419	NM_001393	1842	9q22.3	Hs.117060	9	integrin binding protein binding extracellular region proteinaceous extracellular matrix cell-matrix adhesion
205421_at	-1.530	5.330	-2.602	1.984e-02	0.222	-3.346	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3	6	160689414	NM_021977	6581	6q26-q27	Hs.567337	33	transporter activity protein binding membrane fraction integral to plasma membrane ion transport ion transmembrane transporter activity quaternary ammonium group transmembrane transporter activity quaternary ammonium group transport monoamine transport membrane regulation of appetite histamine uptake
238583_at	-0.502	6.923	-2.602	1.985e-02	0.222	-3.346	MSRB3	methionine sulfoxide reductase B3	12	63958754	BG023974	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
217729_s_at	-0.336	8.376	-2.602	1.986e-02	0.222	-3.346	AES	amino-terminal enhancer of split	19	-3003907, -3003907	NM_001130	166	19p13.3	Hs.515053	24	skeletal system development transcription corepressor activity protein binding nucleus regulation of transcription from RNA polymerase II promoter multicellular organismal development organ morphogenesis negative regulation of specific transcription from RNA polymerase II promoter Wnt receptor signaling pathway negative regulation of transcription transcription regulator activity cellular response to extracellular stimulus negative regulation of protein binding regulation of growth negative regulation of response to cytokine stimulus response to interleukin-1
226333_at	-0.687	7.149	-2.602	1.986e-02	0.222	-3.346	IL6R	interleukin 6 receptor	1	152644292	AV700030	3570	1q21	Hs.709210	132	hepatic immune response monocyte chemotaxis positive regulation of leukocyte chemotaxis receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity receptor binding extracellular region plasma membrane interleukin-6 receptor complex acute-phase response integral to membrane apical plasma membrane enzyme binding endocrine pancreas development endocrine pancreas development positive regulation of chemokine production positive regulation of interleukin-6 production response to cytokine stimulus positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity regulation of apoptosis positive regulation of osteoblast differentiation positive regulation of anti-apoptosis positive regulation of smooth muscle cell proliferation positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium interleukin-6-mediated signaling pathway ciliary neurotrophic factor binding ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage
214520_at	0.366	3.767	2.602	1.986e-02	0.222	-3.346	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	16	85158357	NM_005251	2303	16q22-q24	Hs.436448	45	skeletal system development ossification blood vessel development patterning of blood vessels ureteric bud development lymphangiogenesis blood vessel remodeling heart morphogenesis RNA polymerase II transcription factor activity, enhancer binding nucleus nucleus anti-apoptosis Notch signaling pathway multicellular organismal development mesoderm development cell proliferation insulin receptor signaling pathway response to hormone stimulus neural crest cell development transcription activator activity collagen fibril organization chromatin DNA binding embryonic heart tube development camera-type eye development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter regulation of organ growth vascular endothelial growth factor receptor signaling pathway paraxial mesoderm formation paraxial mesodermal cell fate commitment cell development embryonic viscerocranium morphogenesis artery morphogenesis regulation of blood vessel size ventricular cardiac muscle morphogenesis cardiac muscle cell proliferation
216344_at	0.230	4.282	2.601	1.988e-02	0.222	-3.347	NPHP4	nephronophthisis 4	1	-5845456	AL117405	261734	1p36.22	Hs.462348	13	structural molecule activity protein binding centrosome cilium microtubule basal body signal transduction visual behavior membrane cell-cell adhesion actin cytoskeleton organization
231658_x_at	0.176	2.897	2.601	1.989e-02	0.222	-3.348	RPL36	ribosomal protein L36	19	5641271, 5641345	BG151154	25873	19p13.3	Hs.408018	19	structural constituent of ribosome protein binding intracellular nucleolus cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
212653_s_at	0.280	7.281	2.601	1.990e-02	0.222	-3.348	EHBP1	EH domain binding protein 1	2	62754516, 62786504, 62787535	AB020710	23301	2p15	Hs.271667	13	cytoplasm membrane
209518_at	0.231	7.331	2.601	1.991e-02	0.222	-3.348	SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	12	48765249	AI869240	6602	12q13-q14	Hs.79335	23	transcription coactivator activity nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase II promoter SWI/SNF complex chromatin remodeling complex protein complex scaffold chromatin-mediated maintenance of transcription
225238_at	-0.704	6.014	-2.601	1.991e-02	0.222	-3.348	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BF435123	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
202569_s_at	-0.328	7.347	-2.601	1.991e-02	0.222	-3.348	MARK3	MAP/microtubule affinity-regulating kinase 3	14	102921453	NM_002376	4140	14q32.3	Hs.35828	24	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
235760_at	0.364	5.317	2.601	1.991e-02	0.222	-3.349	NSD1	nuclear receptor binding SET domain protein 1	5	176492685, 176493438	AI421972	64324	5q35.2-q35.3	Hs.106861	36	negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription corepressor activity protein binding nucleus methyltransferase activity zinc ion binding chromatin modification histone methylation transferase activity ligand-dependent nuclear receptor binding estrogen receptor binding histone methyltransferase activity (H4-K20 specific) regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	Lysine degradation
209528_s_at	0.294	6.836	2.600	1.991e-02	0.222	-3.349	TELO2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	16	1483352	AL137394	9894	16p13.3	Hs.271044	13	chromosome, telomeric region protein binding intracellular nucleus chromosome cytoplasm membrane
218815_s_at	0.207	5.326	2.600	1.992e-02	0.222	-3.349	TMEM51	transmembrane protein 51	1	15351614, 15352815	NM_018022	55092	1p36.21	Hs.465305	5	membrane integral to membrane
225468_at	-0.336	6.753	-2.600	1.992e-02	0.222	-3.349	PATL1	protein associated with topoisomerase II homolog 1 (yeast)	11	-59160767	AI761804	219988	11q12.1	Hs.591960	8	cytoplasmic mRNA processing body cytoplasm	RNA degradation
1554171_at	0.330	4.407	2.600	1.993e-02	0.222	-3.350	ZMYM3	zinc finger, MYM-type 3	X	-70376198, -70376198	BC013009	9203	Xq13.1	Hs.522684	12	DNA binding nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding metal ion binding
213334_x_at	0.233	5.869	2.600	1.993e-02	0.222	-3.350	HAUS7	HAUS augmin-like complex, subunit 7	X	-152366317, -152366317	BE676218	55559	Xq28	Hs.170835	16	protein binding centrosome spindle microtubule cell cycle mitosis thioesterase binding cell division HAUS complex
225048_at	-0.452	8.776	-2.600	1.993e-02	0.222	-3.350	PHF10	PHD finger protein 10	6	-169845925	AI818048	55274	6q27	Hs.435933	14	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
228066_at	0.291	6.423	2.600	1.993e-02	0.222	-3.350	C17orf96	chromosome 17 open reading frame 96	17	-34081484	AI870951	100170841	17q12	Hs.445574 Hs.633923	1
215242_at	-0.314	4.111	-2.600	1.995e-02	0.222	-3.350	PIGC	phosphatidylinositol glycan anchor biosynthesis, class C	1	-170677219	AL035301	5279	1q23-q25	Hs.188456	12	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring glycosyl groups phosphatidylinositol N-acetylglucosaminyltransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
216061_x_at	0.301	6.802	2.599	1.995e-02	0.222	-3.350	PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	22	-37949632, -37949632	AU150748	5155	22q12.3-q13.1 22q13.1	Hs.1976	140	response to hypoxia positive regulation of endothelial cell proliferation monocyte chemotaxis platelet-derived growth factor receptor binding collagen binding extracellular region extracellular region cytoplasm substrate-bound cell migration transforming growth factor beta receptor signaling pathway growth factor activity response to wounding cell surface negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation positive regulation of smooth muscle cell migration membrane cell growth cell projection assembly actin cytoskeleton organization negative regulation of cell migration platelet dense granule lumen protein homodimerization activity positive regulation of MAP kinase activity cell surface binding positive regulation of blood vessel endothelial cell migration positive regulation of DNA replication protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding regulation of peptidyl-tyrosine phosphorylation positive regulation of chemotaxis cell chemotaxis	MAPK signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Renal cell carcinoma Glioma Prostate cancer Melanoma
204872_at	-0.560	7.931	-2.599	1.995e-02	0.222	-3.351	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	9	81376697	NM_007005	7091	9q21.31	Hs.444213	12	molecular_function nucleus biological_process Wnt receptor signaling pathway regulation of transcription
217852_s_at	-0.459	8.728	-2.599	1.996e-02	0.222	-3.351	ARL8B	ADP-ribosylation factor-like 8B	3	5138929	NM_018184	55207	3p26.1	Hs.250009 Hs.719100	10	nucleotide binding GTPase activity GTP binding intracellular cytoplasm lysosomal membrane endosome chromosome segregation small GTPase mediated signal transduction membrane GDP binding midbody late endosome membrane alpha-tubulin binding beta-tubulin binding spindle midzone
242662_at	0.366	4.682	2.599	1.996e-02	0.222	-3.351	PCSK6	proprotein convertase subtilisin/kexin type 6	15	-99741475, -99722601, -99704469, -99670747, -99661655	AI056815	5046	15q26.3	Hs.498494 Hs.665989	36	serine-type endopeptidase activity calcium ion binding extracellular region extracellular space soluble fraction endoplasmic reticulum Golgi lumen proteolysis heparin binding peptidase activity glycoprotein metabolic process cell surface membrane regulation of BMP signaling pathway extracellular matrix nerve growth factor processing nerve growth factor production secretion by cell eukaryotic cell surface binding nerve growth factor binding
211505_s_at	-0.306	7.395	-2.599	1.996e-02	0.222	-3.351	STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	20	-47163282	AL136601	6780	20q13.1	Hs.596704	26	double-stranded RNA binding protein binding intracellular rough endoplasmic reticulum microtubule associated complex intracellular mRNA localization ribonucleoprotein complex
1552291_at	-0.422	5.114	-2.599	1.997e-02	0.222	-3.351	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	3	197923642	NM_017861	54965	3q29	Hs.223296	6	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
216309_x_at	0.191	6.609	2.599	1.997e-02	0.222	-3.352	JRK	jerky homolog (mouse)	8	-143735875	AF072467	8629	8q24.3	Hs.535903 Hs.683465	5	molecular_function DNA binding cellular_component nucleus biological_process regulation of transcription
213651_at	0.248	6.539	2.598	2.000e-02	0.222	-3.353	INPP5J	inositol polyphosphate-5-phosphatase J	22	29848960	AI935720	27124	22q11.2-q13.2	Hs.517549	8	ruffle inositol or phosphatidylinositol phosphatase activity inositol-polyphosphate 5-phosphatase activity cytoplasm hydrolase activity SH3 domain binding	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
1557057_a_at	0.195	1.972	2.598	2.000e-02	0.222	-3.353	C5orf47	chromosome 5 open reading frame 47	5	173348767	AL039665	133491	5q35.2	Hs.131469	1
1557481_a_at	-0.261	3.331	-2.598	2.001e-02	0.222	-3.353	C21orf131	chromosome 21 open reading frame 131	21	-21036784	BC042856	387486	21q21.1	Hs.576551 Hs.639558	2
222868_s_at	0.306	4.697	2.598	2.002e-02	0.222	-3.353	IL18BP	interleukin 18 binding protein	11	71387605, 71387756, 71388310, 71388620	AI521549	10068	11q13	Hs.591967	22	extracellular region interleukin-18 binding T-helper 1 type immune response receptor antagonist activity
226588_at	-0.328	5.799	-2.597	2.004e-02	0.222	-3.355	CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	2	-180517848	AB046824	57703	2q31.3	Hs.311363	6	RNA binding protein binding nucleus spliceosomal complex mRNA processing RNA splicing RNA metabolic process regulation of nuclear mRNA splicing, via spliceosome
219793_at	-0.475	4.376	-2.597	2.004e-02	0.222	-3.355	SNX16	sorting nexin 16	8	-82874372	NM_022133	64089	8q21.13	Hs.492121	7	protein binding cell communication protein transport phosphoinositide binding
208081_s_at	0.215	3.703	2.597	2.006e-02	0.222	-3.355	ZNF442	zinc finger protein 442	19	-12321184	NM_030824	79973	19p13.2	Hs.253193	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
218378_s_at	0.273	7.029	2.597	2.006e-02	0.222	-3.355	PRKRIP1	PRKR interacting protein 1 (IL11 inducible)	7	101823808	NM_024653	79706	7q22.1	Hs.406395	6	double-stranded RNA binding protein kinase inhibitor activity protein binding nucleus nucleolus negative regulation of protein kinase activity protein kinase binding negative regulation of phosphorylation
238569_at	0.257	5.076	2.597	2.006e-02	0.222	-3.356	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	6	-29677983, -29677983, -1025320, -1025320, -827282, -827282	N45228	2550	6p21.31	Hs.167017	66	receptor activity G-protein coupled receptor activity GABA-B receptor activity protein binding extracellular region plasma membrane integral to plasma membrane signal transduction negative regulation of adenylate cyclase activity gamma-aminobutyric acid signaling pathway cell junction synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
200011_s_at	0.403	5.875	2.597	2.007e-02	0.222	-3.356	ARF3	ADP-ribosylation factor 3	12	-47616258	NM_001659	377	12q13	Hs.119177 Hs.715625	24	nucleotide binding GTPase activity GTP binding intracellular Golgi apparatus small GTPase mediated signal transduction protein transport vesicle-mediated transport
210225_x_at	0.279	6.474	2.596	2.008e-02	0.222	-3.356	LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	19	-59411958	AF009635	11025	19q13.4	Hs.631592 Hs.688335	14	transmembrane receptor activity integral to plasma membrane defense response immune response cell surface receptor linked signal transduction membrane	B cell receptor signaling pathway
203122_at	0.266	7.758	2.596	2.008e-02	0.222	-3.356	TTC15	tetratricopeptide repeat domain 15	2	3362452	NM_016030	51112	2p25.3	Hs.252713	4	binding
201939_at	0.512	5.403	2.596	2.010e-02	0.223	-3.357	PLK2	polo-like kinase 2 (Drosophila)	5	-57785566	NM_006622	10769	5q12.1-q13.2	Hs.398157 Hs.658132	20	nucleotide binding mitotic cell cycle protein serine/threonine kinase activity signal transducer activity protein binding ATP binding protein amino acid phosphorylation transferase activity polo kinase kinase activity positive regulation of I-kappaB kinase/NF-kappaB cascade
1559634_at	0.245	3.410	2.596	2.011e-02	0.223	-3.357	CHRM3	cholinergic receptor, muscarinic 3	1	237858995	AK056349	1131	1q43	Hs.7138	72	phosphoinositide phospholipase C activity receptor activity G-protein coupled receptor activity muscarinic acetylcholine receptor activity plasma membrane integral to plasma membrane protein modification process signal transduction G-protein coupled receptor protein signaling pathway nervous system development digestion cell proliferation cell junction synapse postsynaptic membrane positive regulation of smooth muscle contraction	Calcium signaling pathway Neuroactive ligand-receptor interaction Regulation of actin cytoskeleton
230110_at	0.373	4.377	2.595	2.011e-02	0.223	-3.358	MCOLN2	mucolipin 2	1	-85163853	AV713773	255231	1p22	Hs.591446	6	ion channel activity ion transport membrane integral to membrane
1554686_at	-0.230	2.361	-2.595	2.012e-02	0.223	-3.358	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)	8	-74624394	BC008370	27067	8q13-q21.1	Hs.561815	11	double-stranded RNA binding intracellular nucleus nucleolus cytoplasm endoplasmic reticulum microtubule transport
212896_at	-0.340	7.316	-2.595	2.013e-02	0.223	-3.359	SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	5	54639332	D29641	23517	5q11.2	Hs.274531	19	nucleotide binding nucleic acid binding helicase activity protein binding ATP binding nucleus spliceosomal complex nucleolus mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RNA degradation
212599_at	-0.564	6.733	-2.595	2.013e-02	0.223	-3.359	AUTS2	autism susceptibility candidate 2	7	68701840, 68701841, 68701841	AK025298	26053	7q11.22	Hs.654801 Hs.712991	13	molecular_function cellular_component biological_process
205038_at	0.302	3.915	2.595	2.013e-02	0.223	-3.359	IKZF1	IKAROS family zinc finger 1 (Ikaros)	7	50314923	BG540504	10320	7p13-p11.1	Hs.435949 Hs.488251	52	DNA binding intracellular nucleus mesoderm development zinc ion binding regulation of transcription metal ion binding
216044_x_at	-0.633	6.107	-2.595	2.014e-02	0.223	-3.359	FAM69A	family with sequence similarity 69, member A	1	-93080308	AK027146	388650	1p22.1	Hs.180946	4	membrane integral to membrane
228751_at	-0.714	6.624	-2.595	2.014e-02	0.223	-3.359	CLK4	CDC-like kinase 4	5	-177962270	AW975057	57396	5q35	Hs.406557	7	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus transferase activity peptidyl-tyrosine phosphorylation protein amino acid autophosphorylation
228184_at	-0.403	5.248	-2.594	2.015e-02	0.223	-3.360	DISP1	dispatched homolog 1 (Drosophila)	1	221168405	AK023679	84976	1q41	Hs.528817	5	multicellular organismal development hedgehog receptor activity membrane integral to membrane
218194_at	0.475	8.905	2.594	2.015e-02	0.223	-3.360	REXO2	REX2, RNA exonuclease 2 homolog (S. cerevisiae)	11	113815317	NM_015523	25996	11q23.1-q23.2	Hs.677190 Hs.7527	15	nucleic acid binding intracellular nucleus mitochondrion nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3'-5' exonuclease activity nucleotide metabolic process hydrolase activity manganese ion binding
237111_at	-0.320	3.863	-2.594	2.016e-02	0.223	-3.360	FLJ44450	hypothetical gene supported by AK126414	2		AW118588	388942	2p21	Hs.631883
222994_at	0.322	9.429	2.594	2.018e-02	0.223	-3.361	PRDX5	peroxiredoxin 5	11	63842144	AF197952	25824	11q13	Hs.502823	37	cytoplasm mitochondrion peroxisome inflammatory response response to oxidative stress oxidoreductase activity cellular response to reactive oxygen species caspase inhibitor activity negative regulation of apoptosis cytosolic part cell redox homeostasis peroxiredoxin activity oxidation reduction
231706_s_at	0.255	3.931	2.593	2.019e-02	0.223	-3.361	EVX1	even-skipped homeobox 1	7	27248688	AI820879	2128	7p15-p14	Hs.369879	5	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development embryonic development ending in birth or egg hatching regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter
226973_at	0.305	5.207	2.593	2.020e-02	0.223	-3.361	VSTM2L	V-set and transmembrane domain containing 2 like	20	35964912	AA206763	128434	20q11.23	Hs.517029	5
226866_at	-0.262	7.587	-2.593	2.021e-02	0.223	-3.362	ESCO1	establishment of cohesion 1 homolog 1 (S. cerevisiae)	18	-17363259	BF211488	114799	18q11.2	Hs.464733	8	damaged DNA binding DNA-directed DNA polymerase activity nucleus DNA repair cell cycle zinc ion binding acyltransferase activity transferase activity metal ion binding
228141_at	0.413	4.206	2.593	2.021e-02	0.223	-3.362	GPX8	glutathione peroxidase 8 (putative)	5	54491740	AA173223	493869	5q11.2	Hs.289044	4	glutathione peroxidase activity response to oxidative stress membrane integral to membrane oxidoreductase activity oxidation reduction
243520_x_at	0.188	1.871	2.593	2.021e-02	0.223	-3.362	ADAM30	ADAM metallopeptidase domain 30	1	-120237678	AI214466	11085	1p13-p11	Hs.283011	6	metalloendopeptidase activity proteolysis peptidase activity zinc ion binding membrane integral to membrane metal ion binding
236905_at	-0.311	4.776	-2.593	2.022e-02	0.223	-3.363	LOC731139	hypothetical LOC731139	1		AI276857	731139	1q42.13
226111_s_at	0.212	5.160	2.592	2.024e-02	0.223	-3.363	ZNF385A	zinc finger protein 385A	12	-53049186, -53049186	BF525395	25946	12q13.13	Hs.505653	8	DNA binding protein binding intracellular nucleus nucleolus cytoplasm zinc ion binding regulation of transcription metal ion binding
204004_at	0.395	4.845	2.592	2.024e-02	0.223	-3.363	PAWR	PRKC, apoptosis, WT1, regulator	12	-78509875	AI336206	5074	12q21	Hs.643130	53	negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus cytoplasm plasma membrane negative regulation of cell proliferation enzyme binding negative regulation of B cell proliferation interleukin-2 biosynthetic process negative regulation of T cell proliferation positive regulation of amyloid precursor protein biosynthetic process positive regulation of apoptosis regulation of transcription negative regulation of T cell receptor signaling pathway
205577_at	-0.517	12.649	-2.592	2.024e-02	0.223	-3.364	PYGM	phosphorylase, glycogen, muscle	11	-64270436	NM_005609	5837	11q12-q13.2	Hs.154084	49	nucleotide binding response to hypoxia protein binding carbohydrate metabolic process glycogen catabolic process cellular calcium ion homeostasis glycogen phosphorylase activity sarcoplasmic reticulum transferase activity, transferring glycosyl groups pyridoxal phosphate binding response to cAMP	Starch and sucrose metabolism Insulin signaling pathway
208173_at	-0.295	4.247	-2.592	2.025e-02	0.223	-3.364	IFNB1	interferon, beta 1, fibroblast	9	-21067103	NM_002176	3456	9p21	Hs.93177	127	transcription corepressor activity cytokine activity interferon-alpha/beta receptor binding extracellular region extracellular space induction of apoptosis activation of caspase activity activation of caspase activity cell surface receptor linked signal transduction negative regulation of cell proliferation response to virus natural killer cell activation negative regulation of viral transcription B cell proliferation defense response to bacterium positive regulation of innate immune response regulation of MHC class I biosynthetic process negative regulation of virion penetration into host cell	Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity
227830_at	0.217	3.524	2.592	2.025e-02	0.223	-3.364	GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	15	-24339786, -24339786	AI478781	2562	15q11.2-q12	Hs.302352 Hs.657298	64	GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport signal transduction cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
206829_x_at	0.309	5.282	2.592	2.026e-02	0.223	-3.364	ZNF430	zinc finger protein 430	19	20995336	NM_025189	80264	19p12	Hs.466289	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
211424_x_at	-0.216	5.596	-2.592	2.026e-02	0.223	-3.365	METTL7A	methyltransferase like 7A	12	49604800	AF113007	25840	12q13.12	Hs.711113 Hs.716437	6	metabolic process methyltransferase activity transferase activity
205471_s_at	0.426	4.605	2.591	2.028e-02	0.223	-3.365	DACH1	dachshund homolog 1 (Drosophila)	13	-70910098	AW772082	1602	13q22	Hs.129452	24	nucleotide binding transcription factor activity protein binding nucleus transcription factor complex cytoplasm multicellular organismal development regulation of transcription
203090_at	-0.198	6.966	-2.591	2.029e-02	0.223	-3.365	SDF2	stromal cell-derived factor 2	17	-23999733	NM_006923	6388	17q11.2	Hs.514036	5	dolichyl-phosphate-mannose-protein mannosyltransferase activity extracellular region extracellular space protein amino acid glycosylation membrane
228054_at	0.220	5.354	2.591	2.029e-02	0.223	-3.365	TMEM44	transmembrane protein 44	3	-195789690	BF593660	93109	3q29	Hs.478729	1	membrane integral to membrane
210552_s_at	0.255	4.523	2.591	2.030e-02	0.223	-3.366	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1	9	128716873	AF221098	9649	9q33.3	Hs.648175	4	guanyl-nucleotide exchange factor activity cellular_component intracellular cytoplasm plasma membrane small GTPase mediated signal transduction
229289_at	0.403	5.567	2.590	2.031e-02	0.223	-3.367	FAM71E1	family with sequence similarity 71, member E1	19	-55661856	AL517395	112703	19q13.33	Hs.448941	1
211994_at	-0.312	9.340	-2.590	2.032e-02	0.223	-3.367	WNK1	WNK lysine deficient protein kinase 1	12	732485	AI742553	65125	12p13.3	Hs.709894	51	nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process
227702_at	-0.579	5.832	-2.590	2.033e-02	0.223	-3.367	CYP4X1	cytochrome P450, family 4, subfamily X, polypeptide 1	1	47261826	AA557324	260293	1p33	Hs.439760	7	monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity
1554027_a_at	-0.268	3.297	-2.590	2.034e-02	0.223	-3.368	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	4	72271866, 72423633	BC030977	8671	4q21	Hs.5462	45	transporter activity inorganic anion exchanger activity plasma membrane integral to plasma membrane sodium ion transport anion transport anion transmembrane transporter activity sodium:bicarbonate symporter activity symporter activity sodium ion binding
214076_at	0.247	6.166	2.590	2.035e-02	0.223	-3.368	GFOD2	glucose-fructose oxidoreductase domain containing 2	16	-66272119, -66265937	AI697803	81577	16q22.1	Hs.461030 Hs.656247	7	binding extracellular region proteinaceous extracellular matrix electron carrier activity oxidoreductase activity extracellular matrix organization oxidation reduction
203441_s_at	0.260	4.898	2.590	2.035e-02	0.223	-3.368	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	18	-23784927	NM_001792	1000	18q11.2	Hs.464829 Hs.606106	102	calcium ion binding plasma membrane adherens junction cell adhesion homophilic cell adhesion heterophilic cell adhesion synaptogenesis integral to membrane calcium-dependent cell-cell adhesion cell migration protein phosphatase binding lamellipodium RPTP-like protein binding synapse blood vessel morphogenesis	Cell adhesion molecules (CAMs) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
220173_at	0.331	4.762	2.590	2.035e-02	0.223	-3.368	C14orf45	chromosome 14 open reading frame 45	14	73555811	NM_025057	80127	14q24.3	Hs.644621	5
207331_at	0.301	3.041	2.589	2.036e-02	0.223	-3.369	CENPF	centromere protein F, 350/400ka (mitosin)	1	212843154	NM_016343	1063	1q32-q41	Hs.497741	33	G2 phase of mitotic cell cycle chromatin spindle pole outer kinetochore of condensed chromosome outer kinetochore of condensed chromosome chromatin binding nucleus nuclear envelope chromosome cytoplasm DNA replication mitosis mitotic cell cycle spindle assembly checkpoint multicellular organismal development muscle organ development protein C-terminus binding transcription factor binding cell proliferation regulation of G2/M transition of mitotic cell cycle protein transport protein transport regulation of striated muscle tissue development nuclear matrix negative regulation of transcription cell differentiation midbody response to drug protein homodimerization activity dynein binding perinuclear region of cytoplasm cell division metaphase plate congression kinetochore assembly
230106_at	-0.193	4.322	-2.589	2.036e-02	0.223	-3.369	ZXDC	ZXD family zinc finger C	3	-127652648, -127639133	BF447897	79364	3q21.3	Hs.440049 Hs.711046	8	nucleic acid binding transcription factor activity intracellular nucleus zinc ion binding transcription activator activity LRR domain binding identical protein binding positive regulation of transcription metal ion binding C2H2 zinc finger domain binding
228647_at	-0.397	6.202	-2.589	2.036e-02	0.223	-3.369	LOC100049716	hypothetical protein LOC100049716	12		AI675844	100049716	12p13.33	Hs.655804	1
234714_x_at	0.193	5.472	2.589	2.038e-02	0.224	-3.370	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	3	-10340706	U15688	491	3p25.3	Hs.268942	30	nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding cytoplasm plasma membrane ATP biosynthetic process cation transport calcium ion transport sensory perception of sound metabolic process integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances neuron differentiation	Calcium signaling pathway
205711_x_at	0.353	11.710	2.589	2.039e-02	0.224	-3.370	ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	10	7870098	NM_005174	509	10p15.1	Hs.271135	18	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) mitochondrion mitochondrion mitochondrial matrix ion transport ATP synthesis coupled proton transport proton transport membrane ATPase activity ATPase activity hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1553743_at	-0.495	6.666	-2.588	2.040e-02	0.224	-3.371	FAM119A	family with sequence similarity 119, member A	2	-208182083, -208182083	NM_145280	151194	2q33.3	Hs.664764	2	membrane integral to membrane
1570447_at	-0.203	4.417	-2.588	2.040e-02	0.224	-3.371	FLJ44054	hypothetical protein LOC643365	13	-113487457	BC034570	643365	13q34	Hs.680435	1
214180_at	0.267	5.544	2.588	2.041e-02	0.224	-3.371	MAN1C1	mannosidase, alpha, class 1C, member 1	1	25816545	AW340588	57134	1p35	Hs.197043	26	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding Golgi apparatus protein amino acid N-linked glycosylation metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds integral to Golgi membrane	N-Glycan biosynthesis Metabolic pathways
201424_s_at	-0.269	9.520	-2.588	2.042e-02	0.224	-3.371	CUL4A	cullin 4A	13	112911086, 112911931	NM_003589	8451	13q34	Hs.339735	48	G1/S transition of mitotic cell cycle protein binding DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
213287_s_at	-0.371	8.508	-2.588	2.043e-02	0.224	-3.372	KRT10	keratin 10	17	-36227895	X14487	3858	17q21	Hs.99936	49	protein binding intermediate filament epidermis development structural constituent of epidermis
207092_at	0.490	4.178	2.587	2.044e-02	0.224	-3.372	LEP	leptin	7	127668566	NM_000230	3952	7q31.3	Hs.194236	628	response to dietary excess hormone activity protein binding extracellular region extracellular space glucose metabolic process regulation of gluconeogenesis energy reserve metabolic process lipid metabolic process signal transduction growth factor activity cholesterol metabolic process bile acid metabolic process adult feeding behavior regulation of metabolic process central nervous system neuron development regulation of intestinal cholesterol absorption negative regulation of appetite response to insulin stimulus hormone metabolic process eating behavior positive regulation of myeloid cell differentiation regulation of insulin secretion regulation of steroid biosynthetic process	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Jak-STAT signaling pathway Adipocytokine signaling pathway
1552770_s_at	0.244	4.807	2.587	2.045e-02	0.224	-3.373	ZNF563	zinc finger protein 563	19	-12289305	NM_145276	147837	19p13.2	Hs.663510	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
231678_s_at	0.225	2.289	2.587	2.046e-02	0.224	-3.373	ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide	4	-100263855	AV651117	127	4q21-q24 4q22	Hs.1219	30	NADPH:quinone reductase activity alcohol dehydrogenase activity, zinc-dependent aldehyde reductase activity retinol dehydrogenase activity binding all-trans retinal binding cellular_component cytoplasm ethanol oxidation cellular aldehyde metabolic process zinc ion binding oxidoreductase activity benzaldehyde dehydrogenase activity retinol binding quinone cofactor metabolic process retinol metabolic process alcohol catabolic process metal ion binding NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
238706_at	-0.378	4.146	-2.586	2.048e-02	0.224	-3.374	PAPD4	PAP associated domain containing 4	5	78943998	BG168850	167153	5q14.1	Hs.418198	5	nucleotide binding polynucleotide adenylyltransferase activity ATP binding nucleus cytoplasm mRNA processing transferase activity nuclear RNA-directed RNA polymerase complex RNA polyadenylation
209685_s_at	0.367	4.286	2.586	2.048e-02	0.224	-3.374	PRKCB	protein kinase C, beta	16	23754800	M13975	5579	16p11.2	Hs.460355	235	nucleotide binding protein kinase C activity calcium channel regulator activity calcium ion binding protein binding ATP binding nucleus cytoplasm cytosol plasma membrane plasma membrane protein amino acid phosphorylation calcium ion transport cellular calcium ion homeostasis intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding lipoprotein transport	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Wnt signaling pathway VEGF signaling pathway Focal adhesion Tight junction Gap junction Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Vibrio cholerae infection Pathways in cancer Glioma Non-small cell lung cancer
203547_at	0.246	6.362	2.586	2.048e-02	0.224	-3.374	CD4	CD4 molecule	12	6768911	U47924	920	12pter-p12	Hs.631659	992	conjugation with cellular fusion cytokine production glycoprotein binding transmembrane receptor activity extracellular matrix structural constituent early endosome endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane plasma membrane protein amino acid N-linked glycosylation immune response cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway zinc ion binding external side of plasma membrane coreceptor activity integral to membrane initiation of viral infection protein kinase binding T cell receptor complex MHC class II protein binding protein homodimerization activity interspecies interaction between organisms T cell selection positive regulation of interleukin-2 biosynthetic process membrane raft positive regulation of protein kinase activity positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling positive regulation of T cell activation response to protein stimulus	Cell adhesion molecules (CAMs) Antigen processing and presentation Hematopoietic cell lineage T cell receptor signaling pathway Primary immunodeficiency
204347_at	0.323	5.202	2.586	2.050e-02	0.224	-3.375	AK3L1	adenylate kinase 3-like 1	1	65385819, 65386100, 65386473	AI653169	205	1p31.3	Hs.10862 Hs.592601	10	nucleotide binding adenylate kinase activity ATP binding GTP binding mitochondrion mitochondrial matrix nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity	Purine metabolism Metabolic pathways
210774_s_at	-0.305	10.935	-2.586	2.051e-02	0.224	-3.375	NCOA4	nuclear receptor coactivator 4	10	51235113, 51242369, 51246290	AL162047	8031	10q11.2	Hs.643658 Hs.709644	43	transcription coactivator activity protein binding nucleus male gonad development androgen receptor signaling pathway regulation of transcription positive regulation of transcription, DNA-dependent androgen receptor binding	Pathways in cancer Thyroid cancer
206993_at	0.583	7.515	2.586	2.051e-02	0.224	-3.375	ATP5S	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)	14	49848796, 49848796	NM_015684	27109	14q21.3	Hs.438489	12	mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o)
201966_at	0.258	11.400	2.585	2.053e-02	0.224	-3.376	NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	1	159435728	NM_004550	4720	1q23	Hs.173611	19	NADH dehydrogenase activity iron ion binding protein binding mitochondrion mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport response to oxidative stress NADH dehydrogenase (ubiquinone) activity electron carrier activity membrane electron transport chain metal ion binding quinone binding NAD or NADH binding 4 iron, 4 sulfur cluster binding respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
212226_s_at	0.309	8.307	2.585	2.054e-02	0.224	-3.377	PPAP2B	phosphatidic acid phosphatase type 2B	1	-56733020	AA628586	8613	1pter-p22.1	Hs.405156 Hs.715848	16	blood vessel development gastrulation with mouth forming second phosphoprotein phosphatase activity Golgi apparatus cytosol plasma membrane lipid metabolic process phospholipid metabolic process phosphatidate phosphatase activity phosphatidate phosphatase activity germ cell migration integral to membrane hydrolase activity regulation of Wnt receptor signaling pathway lipid phosphatase activity	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
205950_s_at	0.336	6.433	2.585	2.054e-02	0.224	-3.377	CA1	carbonic anhydrase I	8	-86427709, -86427709	NM_001738	759	8q13-q22.1	Hs.23118	30	carbonate dehydratase activity cytoplasm one-carbon metabolic process zinc ion binding lyase activity metal ion binding	Nitrogen metabolism
205027_s_at	-0.300	3.152	-2.585	2.055e-02	0.224	-3.377	MAP3K8	mitogen-activated protein kinase kinase kinase 8	10	30762871	NM_005204	1326	10p11.23	Hs.432453	46	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation cell cycle signal transduction transferase activity	MAPK signaling pathway Toll-like receptor signaling pathway T cell receptor signaling pathway
233298_at	0.229	3.210	2.585	2.055e-02	0.224	-3.377	C13orf38	chromosome 13 open reading frame 38	13	-35703215, -35699181	AL139377	728591	13q13.3	Hs.124519 Hs.656745	3
232011_s_at	0.323	6.301	2.584	2.056e-02	0.224	-3.378	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	AL118520	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
212234_at	-0.385	6.339	-2.583	2.060e-02	0.225	-3.379	ASXL1	additional sex combs like 1 (Drosophila)	20	30409813	AL034550	171023	20q11.1	Hs.374043	13	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
229577_at	0.251	5.122	2.583	2.061e-02	0.225	-3.380	AGPAT6	1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)	8	41554863	AI742085	137964	8p11.21	Hs.355753	7	glandular epithelial cell maturation 1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity membrane fraction endoplasmic reticulum endoplasmic reticulum acyl-CoA metabolic process phosphatidylcholine biosynthetic process lactation metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process triglyceride biosynthetic process regulation of multicellular organism growth diacylglycerol metabolic process	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways
225198_at	-0.392	8.089	-2.583	2.063e-02	0.225	-3.381	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa	18	9903954	AL571942	9218	18p11.22	Hs.699980	18	signal transducer activity structural molecule activity protein binding membrane fraction endoplasmic reticulum microtubule plasma membrane tight junction membrane fusion integral to membrane vesicle positive regulation of I-kappaB kinase/NF-kappaB cascade protein heterodimerization activity perinuclear region of cytoplasm	Tight junction
224318_s_at	-0.392	8.751	-2.583	2.063e-02	0.225	-3.381	KIAA1310	KIAA1310	2	-96622633	AF311326	55683	2p12-p11.2	Hs.516341	10
225474_at	0.518	5.455	2.583	2.063e-02	0.225	-3.381	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	3	-65319983, -65314945	AI141556	9223	3p14.1	Hs.651939	24	nucleotide binding ATP binding plasma membrane cell-cell junction tight junction protein complex assembly cell adhesion cell surface receptor linked signal transduction protein C-terminus binding	Tight junction
1554126_at	-0.356	8.070	-2.582	2.066e-02	0.225	-3.382	MSRB3	methionine sulfoxide reductase B3	12	63958754	BC040053	253827	12q14.3	Hs.339024	6	mitochondrion endoplasmic reticulum peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity metal ion binding oxidation reduction
213021_at	-0.379	6.571	-2.582	2.067e-02	0.225	-3.382	GOSR1	golgi SNAP receptor complex member 1	17	25828551	AI741876	9527	17q11	Hs.462680	18	Golgi membrane SNAP receptor activity Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport SNARE complex retrograde transport, endosome to Golgi	SNARE interactions in vesicular transport
201556_s_at	-0.281	5.130	-2.581	2.070e-02	0.226	-3.384	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	17	-8003189	BC002737	6844	17p13.1	Hs.25348	66	protein binding integral to plasma membrane membrane vesicle-mediated transport synaptosome cell junction cytoplasmic vesicle synapse	SNARE interactions in vesicular transport
224983_at	-0.257	9.933	-2.581	2.071e-02	0.226	-3.384	SCARB2	scavenger receptor class B, member 2	4	-77298917	BF339821	950	4q21.1	Hs.349656 Hs.714206	24	receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane	Lysosome
231929_at	-0.595	5.666	-2.580	2.073e-02	0.226	-3.385	IKZF2	IKAROS family zinc finger 2 (Helios)	2	-213572655, -213572655	AI458439	22807	2q34	Hs.604950	15	molecular_function DNA binding intracellular nucleus biological_process zinc ion binding regulation of transcription metal ion binding
201409_s_at	-0.399	9.131	-2.580	2.074e-02	0.226	-3.385	PPP1CB	protein phosphatase 1, catalytic subunit, beta isoform	2	28828117, 28828129	NM_002709	5500	2p23	Hs.591571 Hs.702907	42	protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm carbohydrate metabolic process glycogen metabolic process protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding cell division MLL5-L complex	Vascular smooth muscle contraction Focal adhesion Long-term potentiation Regulation of actin cytoskeleton Insulin signaling pathway
205976_at	-0.322	3.645	-2.580	2.074e-02	0.226	-3.386	FASTKD2	FAST kinase domains 2	2	207338356	NM_014929	22868	2q33.3	Hs.5930	8	protein kinase activity ATP binding apoptosis
236285_at	0.699	4.473	2.580	2.076e-02	0.226	-3.386	KLHDC7B	kelch domain containing 7B	22	49333327	AI631846	113730	22q13.33	Hs.137007	3
213715_s_at	0.312	6.080	2.579	2.077e-02	0.226	-3.387	KANK3	KN motif and ankyrin repeat domains 3	19	-8293467	AF070591	256949	19p13.2	Hs.322473	6
239824_s_at	0.424	4.861	2.579	2.077e-02	0.226	-3.387	TMEM107	transmembrane protein 107	17	-8017020	BF971873	84314	17p13.1	Hs.513933	4	molecular_function cellular_component biological_process membrane integral to membrane
215016_x_at	-0.219	10.701	-2.579	2.077e-02	0.226	-3.387	DST	dystonin	6	-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743	BC004912	667	6p12.1	Hs.631992 Hs.669931	48	actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding
231959_at	-0.326	5.897	-2.579	2.079e-02	0.226	-3.387	LIN52	lin-52 homolog (C. elegans)	14	73621408	AK023979	91750	14q24.3	Hs.612866	6
230591_at	0.432	6.152	2.579	2.079e-02	0.226	-3.388	LOC729887	hypothetical protein LOC729887	16		AI792242	729887	16q23.3	Hs.568369	1
221935_s_at	-0.472	5.848	-2.579	2.080e-02	0.226	-3.388	C3orf64	chromosome 3 open reading frame 64	3	-69107057	AK023140	285203	3p14.1	Hs.518059	2	extracellular region endoplasmic reticulum transferase activity, transferring glycosyl groups
227557_at	0.278	4.267	2.578	2.081e-02	0.226	-3.388	SCARF2	scavenger receptor class F, member 2	22	-19108874	AI127800	91179	22q11.21	Hs.474251	4	receptor activity scavenger receptor activity protein binding cell adhesion heterophilic cell adhesion membrane integral to membrane
208642_s_at	-0.299	8.198	-2.578	2.082e-02	0.226	-3.389	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	2	216682264	AA205834	7520	2q35	Hs.388739	148	nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding promoter binding hydrolase activity provirus integration initiation of viral infection	Non-homologous end-joining
222986_s_at	0.254	6.243	2.578	2.083e-02	0.226	-3.389	SHISA5	shisa homolog 5 (Xenopus laevis)	3	-48484200	BC001463	51246	3p21.31	Hs.414579	7	signal transducer activity nucleus endoplasmic reticulum apoptosis membrane integral to membrane nuclear membrane positive regulation of I-kappaB kinase/NF-kappaB cascade	p53 signaling pathway
210736_x_at	-0.378	6.136	-2.578	2.084e-02	0.226	-3.390	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U46746	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
224321_at	-0.987	5.079	-2.578	2.084e-02	0.226	-3.390	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2	2	-192522991	AB004064	23671	2q32.3	Hs.144513	31	molecular_function extracellular region membrane integral to membrane
228489_at	0.502	5.183	2.578	2.084e-02	0.226	-3.390	TM4SF18	transmembrane 4 L six family member 18	3	-150521544	AI721164	116441	3q25.1	Hs.22026	3	membrane integral to membrane
207622_s_at	-0.342	6.421	-2.577	2.085e-02	0.226	-3.390	ABCF2	ATP-binding cassette, sub-family F (GCN20), member 2	7	-150540508, -150535855	NM_005692	10061	7q36	Hs.654958	15	nucleotide binding transporter activity ATP binding mitochondrial envelope transport ATPase activity ATP-binding cassette (ABC) transporter complex
223249_at	-0.352	7.598	-2.577	2.085e-02	0.226	-3.390	CLDN12	claudin 12	7	89870731	AL136770	9069	7q21	Hs.258576	21	structural molecule activity plasma membrane tight junction integral to membrane calcium-independent cell-cell adhesion cell junction identical protein binding
210104_at	-0.286	6.849	-2.577	2.086e-02	0.226	-3.391	MED6	mediator complex subunit 6	14	-70120709	AF074723	10001	14q24.2	Hs.497353	22	RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter
219409_at	-0.304	4.446	-2.577	2.087e-02	0.226	-3.391	SNIP1	Smad nuclear interacting protein 1	1	-37774728	NM_024700	79753	1p34.3	Hs.471951	14	protein binding nucleus regulation of transcription, DNA-dependent I-kappaB kinase/NF-kappaB cascade
202709_at	0.390	6.329	2.577	2.087e-02	0.226	-3.391	FMOD	fibromodulin	1	-201576374	NM_002023	2331	1q32	Hs.519168	22	protein binding extracellular region proteinaceous extracellular matrix transforming growth factor beta receptor complex assembly
200004_at	-0.326	11.047	-2.577	2.087e-02	0.226	-3.391	EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	11	-10775168	NM_001418	1982	11p15	Hs.183684	39	translation initiation factor activity protein binding regulation of translational initiation cell cycle arrest cell death RNA metabolic process eukaryotic translation initiation factor 4F complex
229113_s_at	0.351	5.894	2.577	2.087e-02	0.226	-3.391	C1orf86	chromosome 1 open reading frame 86	1	-2110847	W16779	199990	1p36.33	Hs.107101 Hs.719244	5
224892_at	-0.408	8.185	-2.577	2.087e-02	0.226	-3.391	PLDN	pallidin homolog (mouse)	15	43666708	BF680495	26258	15q21.1	Hs.719102	17	cellular_component cytoplasm endosome membrane fusion blood coagulation membrane synaptic vesicle docking during exocytosis melanocyte differentiation syntaxin-13 binding positive regulation of natural killer cell activation secretion of lysosomal enzymes identical protein binding pigmentation
225868_at	0.243	6.118	2.577	2.087e-02	0.226	-3.391	TRIM47	tripartite motif-containing 47	17	-71381839	AW249467	91107	17q24-q25	Hs.293660	5	protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding
226484_at	-0.293	8.379	-2.577	2.088e-02	0.226	-3.391	ZBTB47	zinc finger and BTB domain containing 47	3	42675877	AA532640	92999	3p22.1	Hs.409561	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203187_at	0.278	5.490	2.576	2.089e-02	0.226	-3.392	DOCK1	dedicator of cytokinesis 1	10	128584012	NM_001380	1793	10q26.13-q26.3	Hs.159195 Hs.645702	39	guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm phagocytosis, engulfment apoptosis signal transduction integrin-mediated signaling pathway small GTPase mediated signal transduction membrane SH3 domain binding	Focal adhesion Regulation of actin cytoskeleton
213617_s_at	0.302	5.454	2.576	2.090e-02	0.226	-3.392	C18orf10	chromosome 18 open reading frame 10	18	-32630031	BF063896	25941	18q12.2	Hs.695999	5	cytoplasm cytoskeleton microtubule
214429_at	-0.317	7.651	-2.576	2.091e-02	0.226	-3.393	MTMR6	myotubularin related protein 6	13	-24718340	U47635	9107	13q12	Hs.643702	17	protein serine/threonine phosphatase activity protein tyrosine phosphatase activity cellular_component nucleus nuclear envelope cytoplasm protein amino acid dephosphorylation calcium-activated potassium channel activity hydrolase activity phosphatase activity	Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways
203542_s_at	-0.623	7.944	-2.576	2.092e-02	0.226	-3.393	KLF9	Kruppel-like factor 9	9	-72189332	AI690205	687	9q13	Hs.150557 Hs.602267	19	transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter embryo implantation zinc ion binding regulation of transcription metal ion binding progesterone receptor signaling pathway
201127_s_at	0.230	5.530	2.576	2.092e-02	0.226	-3.393	ACLY	ATP citrate lyase	17	-37276704	AI971281	47	17q12-q21	Hs.387567	22	nucleotide binding magnesium ion binding ATP citrate synthase activity succinate-CoA ligase (ADP-forming) activity protein binding ATP binding cytoplasm cytosol citrate metabolic process ATP catabolic process metabolic process lipid biosynthetic process citrate (pro-3S)-lyase activity citrate lyase complex coenzyme A metabolic process transferase activity cellular carbohydrate metabolic process	Citrate cycle (TCA cycle) Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
236831_at	-0.379	4.498	-2.576	2.092e-02	0.226	-3.393	CCDC50	coiled-coil domain containing 50	3	192529567	AV683852	152137	3q28	Hs.478682	12	protein binding cytoplasm
220148_at	-0.849	3.329	-2.575	2.094e-02	0.226	-3.394	ALDH8A1	aldehyde dehydrogenase 8 family, member A1	6	-135280220	NM_022568	64577	6q23.2	Hs.486520	5	retinal dehydrogenase activity intracellular cytoplasm oxidoreductase activity retinoic acid metabolic process retinal metabolic process oxidation reduction
212493_s_at	-0.308	7.673	-2.575	2.095e-02	0.226	-3.394	SETD2	SET domain containing 2	3	-47032903	AI761110	29072	3p21.31	Hs.517941	18	DNA binding protein binding nucleus methyltransferase activity oxidoreductase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription transition metal ion binding	Lysine degradation
222683_at	-0.367	7.976	-2.575	2.095e-02	0.226	-3.395	RNF20	ring finger protein 20	9	103335953	AK022532	56254	9q22	Hs.656088	19	ubiquitin ligase complex protein polyubiquitination p53 binding transcription coactivator activity ubiquitin-protein ligase activity nucleus chromosome nucleolus ubiquitin-dependent protein catabolic process zinc ion binding histone monoubiquitination chromatin modification ligase activity negative regulation of cell migration ubiquitin protein ligase binding regulation of gene-specific transcription histone H2B ubiquitination histone H3-K79 methylation histone binding positive regulation of transcription metal ion binding histone H3-K4 methylation
210119_at	0.358	3.506	2.574	2.097e-02	0.226	-3.395	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	21	38550533, 38550739, 38566298	U73191	3772	21q22.2	Hs.411299	18	inward rectifier potassium channel activity voltage-gated ion channel activity potassium channel activity protein binding cytoplasm plasma membrane integral to plasma membrane focal adhesion ion transport potassium ion transport potassium ion binding
1562743_at	0.285	4.691	2.574	2.098e-02	0.226	-3.396	ZNF33B	zinc finger protein 33B	10	-42404560	BC042873	7582	10q11.2	Hs.499453	9	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1557544_at	-0.580	3.819	-2.574	2.099e-02	0.226	-3.396	CCDC147	coiled-coil domain containing 147	10	106103511	BC036225	159686	10q25.1	Hs.253576	4
211056_s_at	0.243	4.562	2.574	2.100e-02	0.226	-3.396	SRD5A1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	5	6686499	BC006373	6715	5p15	Hs.552	50	3-oxo-5-alpha-steroid 4-dehydrogenase activity cytoplasm endoplasmic reticulum microsome lipid metabolic process androgen biosynthetic process sex determination steroid metabolic process electron carrier activity membrane integral to membrane oxidoreductase activity, acting on the CH-CH group of donors cell differentiation oxidation reduction	Androgen and estrogen metabolism
212851_at	-0.350	6.005	-2.574	2.100e-02	0.226	-3.397	DCUN1D4	DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)	4	52404032	AA194584	23142	4q12	Hs.605388	10	nucleus
235714_at	-0.310	4.247	-2.574	2.101e-02	0.226	-3.397	GANC	glucosidase, alpha; neutral C	15	40353657	AA203132	2595	15q15.2	Hs.143261	44	hydrolase activity, hydrolyzing O-glycosyl compounds alpha-glucosidase activity carbohydrate metabolic process metabolic process	Galactose metabolism Starch and sucrose metabolism Metabolic pathways
223515_s_at	0.344	8.955	2.573	2.101e-02	0.226	-3.397	COQ3	coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	6	-99924068	AL136726	51805	6q16.2	Hs.713623	6	hexaprenyldihydroxybenzoate methyltransferase activity mitochondrion mitochondrial matrix glycerol metabolic process ubiquinone biosynthetic process metabolic process O-methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity transferase activity	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
212331_at	-0.383	7.883	-2.573	2.103e-02	0.226	-3.398	RBL2	retinoblastoma-like 2 (p130)	16	52025851	X76061	5934	16q12.2	Hs.513609	93	DNA binding protein binding nucleus cell cycle chromatin modification regulation of lipid kinase activity regulation of transcription	Cell cycle TGF-beta signaling pathway
241347_at	0.245	5.510	2.573	2.103e-02	0.226	-3.398	KIAA1618	KIAA1618	17	75849261	AA936632	57714	17q25.3	Hs.514554	5
215049_x_at	0.508	5.359	2.573	2.104e-02	0.226	-3.398	CD163	CD163 molecule	12	-7514676	Z22969	9332	12p13.3	Hs.504641	51	scavenger receptor activity protein binding extracellular region plasma membrane integral to plasma membrane acute-phase response inflammatory response
243256_at	0.233	5.437	2.573	2.104e-02	0.226	-3.398	MKNK1	MAP kinase interacting serine/threonine kinase 1	1	-46795677	AW796364	8569	1p33	Hs.371594	28	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm regulation of translation protein amino acid phosphorylation response to stress protein kinase cascade transferase activity	MAPK signaling pathway Insulin signaling pathway
228816_at	0.400	6.325	2.573	2.104e-02	0.226	-3.399	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	5	81636921	AK022625	92270	5q14.2	Hs.364045	2	ATP synthesis coupled proton transport membrane integral to membrane proton-transporting V-type ATPase, V1 domain hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism
206066_s_at	0.374	6.410	2.573	2.105e-02	0.226	-3.399	RAD51C	RAD51 homolog C (S. cerevisiae)	17	54124961, 54124961	NM_002876	5889	17q22-q23	Hs.412587	33	nucleotide binding DNA binding ATP binding nucleus DNA repair response to DNA damage stimulus female meiosis sister chromatid cohesion reciprocal meiotic recombination male meiosis I spermatogenesis DNA-dependent ATPase activity crossover junction endodeoxyribonuclease activity nucleoside-triphosphatase activity	Homologous recombination
226342_at	-0.423	6.899	-2.572	2.108e-02	0.227	-3.400	SPTBN1	spectrin, beta, non-erythrocytic 1	2	54536957, 54639034	AW593244	6711	2p21	Hs.503178 Hs.705692	46	actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping
203861_s_at	-0.420	12.563	-2.572	2.108e-02	0.227	-3.400	ACTN2	actinin, alpha 2	1	234916392	AU146889	88	1q42-q43	Hs.498178	57	actin binding integrin binding calcium ion binding nucleolus cytoplasm cytoskeleton actin filament focal adhesion muscle contraction cell adhesion structural constituent of muscle Z disc microspike assembly filopodium thyroid hormone receptor coactivator activity pseudopodium titin binding identical protein binding regulation of apoptosis dendritic spine protein dimerization activity focal adhesion formation protein homotetramerization ZASP binding FATZ 1 binding titin Z domain binding	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Systemic lupus erythematosus Arrhythmogenic right ventricular cardiomyopathy (ARVC)
213227_at	-0.332	7.810	-2.572	2.109e-02	0.227	-3.400	PGRMC2	progesterone receptor membrane component 2	4	-129410746	BE879873	10424	4q26	Hs.507910	9	steroid hormone receptor activity receptor activity steroid binding protein binding membrane integral to membrane heme binding
243354_at	0.296	2.574	2.571	2.110e-02	0.227	-3.401	HYDIN	hydrocephalus inducing homolog (mouse)	16	-69618511, -69398789	AI027184	54768	16q22.2	Hs.461229 Hs.669795	5
227711_at	0.999	3.836	2.571	2.112e-02	0.227	-3.402	GTSF1	gametocyte specific factor 1	12	-53136002	BG150433	121355	12q13.13	Hs.524476	3	cytoplasm zinc ion binding metal ion binding
236535_at	-0.325	5.036	-2.571	2.112e-02	0.227	-3.402	SMC6	structural maintenance of chromosomes 6	2	-17708559	AW069285	79677	2p24.2	Hs.526728	15	nucleotide binding ATP binding intracellular nucleus chromosome DNA repair DNA recombination response to DNA damage stimulus
221660_at	0.334	7.042	2.571	2.112e-02	0.227	-3.402	MYL10	myosin, light chain 10, regulatory	7	-101043325	BC002778	93408	7q22.1	Hs.247831	6	calcium ion binding mitochondrion	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
223288_at	-0.733	8.835	-2.571	2.112e-02	0.227	-3.402	USP38	ubiquitin specific peptidase 38	4	144325519	AW977401	84640		Hs.480848	7	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
200840_at	-0.436	11.286	-2.571	2.113e-02	0.227	-3.402	KARS	lysyl-tRNA synthetase	16	-74219122	NM_005548	3735	16q23-q24	Hs.3100	30	nucleotide binding nucleic acid binding lysine-tRNA ligase activity ATP binding soluble fraction cytoplasm lysyl-tRNA aminoacylation ligase activity	Aminoacyl-tRNA biosynthesis
90610_at	-0.262	7.515	-2.569	2.118e-02	0.227	-3.404	LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4	7	-100009569	AI654857	4034	7q22	Hs.125742	11	protein binding cytoplasm nervous system development negative regulation of transcription transcription repressor activity PML body
225509_at	-0.372	7.304	-2.569	2.119e-02	0.227	-3.405	SAP30L	SAP30-like	5	153805709	AI862477	79685	5q33.2	Hs.592566	8	nucleus nucleolus regulation of transcription
237052_x_at	-0.303	6.615	-2.569	2.120e-02	0.227	-3.405	GIGYF2	GRB10 interacting GYF protein 2	2	233270258	BE220828	26058	2q37.1	Hs.565319	23	protein binding
224719_s_at	0.345	9.100	2.568	2.123e-02	0.228	-3.406	C12orf57	chromosome 12 open reading frame 57	12	6923463	BG339653	113246	12p13.31	Hs.405913 Hs.591045	5
217989_at	0.499	5.534	2.568	2.123e-02	0.228	-3.407	HSD17B11	hydroxysteroid (17-beta) dehydrogenase 11	4	-88476714	NM_016245	51170	4q22.1	Hs.594923	14	estradiol 17-beta-dehydrogenase activity binding extracellular region nucleus cytoplasm steroid biosynthetic process androgen catabolic process steroid dehydrogenase activity oxidation reduction
212975_at	0.239	6.000	2.568	2.124e-02	0.228	-3.407	DENND3	DENN/MADD domain containing 3	8	142207901	AB020677	22898	8q24.3	Hs.18166	5
220983_s_at	-0.506	4.972	-2.568	2.125e-02	0.228	-3.407	SPRY4	sprouty homolog 4 (Drosophila)	5	-141670175	NM_030964	81848	5q31.3	Hs.323308	14	protein binding cytoplasm plasma membrane multicellular organismal development regulation of signal transduction cell projection negative regulation of MAP kinase activity	Jak-STAT signaling pathway
204154_at	0.807	5.867	2.568	2.126e-02	0.228	-3.408	CDO1	cysteine dioxygenase, type I	5	-115168328	NM_001801	1036	5q22-q23	Hs.442378	12	sulfur amino acid biosynthetic process iron ion binding cytosol inflammatory response oxidoreductase activity cysteine dioxygenase activity taurine biosynthetic process L-cysteine metabolic process metal ion binding oxidation reduction	Cysteine and methionine metabolism Taurine and hypotaurine metabolism Metabolic pathways
226677_at	0.551	3.758	2.567	2.127e-02	0.228	-3.408	ZNF521	zinc finger protein 521	18	-20895885	AF141339	25925	18q11.2	Hs.116935	9
202322_s_at	-0.274	8.013	-2.567	2.128e-02	0.228	-3.409	GGPS1	geranylgeranyl diphosphate synthase 1	1	233558375, 233558491	NM_004837	9453	1q43	Hs.719270	13	dimethylallyltranstransferase activity farnesyltranstransferase activity geranyltranstransferase activity soluble fraction cytoplasm isoprenoid biosynthetic process transferase activity	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
41856_at	0.206	7.104	2.567	2.129e-02	0.228	-3.409	UNC5B	unc-5 homolog B (C. elegans)	10	72642303	AL049370	219699	10q22.1	Hs.522997	12	receptor activity protein binding apoptosis signal transduction multicellular organismal development membrane integral to membrane	Axon guidance
201685_s_at	-0.374	7.534	-2.567	2.129e-02	0.228	-3.409	TOX4	TOX high mobility group box family member 4	14	21015174	NM_014828	9878	14q11.2	Hs.555910	9	DNA binding nucleus nucleolus Golgi apparatus
235173_at	-0.598	10.884	-2.566	2.132e-02	0.228	-3.410	hCG_1806964	hypothetical LOC401093	3	-153463102	AA093668	401093	3q25.1	Hs.201858 Hs.558914 Hs.719379	3
229655_at	0.236	3.807	2.566	2.134e-02	0.228	-3.411	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	22	47263951, 47350781	N66656	25817	22q13.32	Hs.436854 Hs.632788	8	extracellular region membrane integral to membrane
214736_s_at	-0.303	7.879	-2.566	2.134e-02	0.228	-3.411	ADD1	adducin 1 (alpha)	4	2815381	BE898639	118	4p16.3	Hs.183706 Hs.701490	139	calmodulin binding nucleus cytoplasm cytosol cytoskeleton plasma membrane transcription factor binding F-actin capping protein complex actin cytoskeleton organization spectrin binding positive regulation of protein binding protein homodimerization activity metal ion binding protein heterodimerization activity actin filament binding barbed-end actin filament capping actin filament bundle formation
219595_at	0.242	5.541	2.565	2.135e-02	0.228	-3.412	ZNF26	zinc finger protein 26	12	132073128	NM_019591	7574	12q24.33	Hs.489608	7	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
219694_at	0.272	3.245	2.565	2.137e-02	0.228	-3.412	FAM105A	family with sequence similarity 105, member A	5	14634890	NM_019018	54491	5p15.2	Hs.155085	6
202282_at	0.287	8.494	2.565	2.138e-02	0.228	-3.413	HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	X	-53474930	NM_004493	3028	Xp11.2	Hs.171280	40	3-hydroxyacyl-CoA dehydrogenase activity protein binding cytoplasm mitochondrion plasma membrane lipid metabolic process tRNA processing 7-alpha-hydroxysteroid dehydrogenase activity oxidoreductase activity 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity oxidation reduction	Valine, leucine and isoleucine degradation Metabolic pathways Alzheimer's disease
44702_at	0.243	6.734	2.565	2.138e-02	0.228	-3.413	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	19	15079213	R77097	85360	19p13.12	Hs.528701 Hs.706845	2	GTPase activator activity Rho GTPase activator activity intracellular signal transduction activation of Rho GTPase activity
218749_s_at	0.223	6.374	2.565	2.138e-02	0.228	-3.413	SLC24A6	solute carrier family 24 (sodium/potassium/calcium exchanger), member 6	12	-112220953	NM_024959	80024	12q24.13	Hs.286194	6	calcium ion binding plasma membrane ion transport sodium ion transport calcium ion transport antiporter activity integral to membrane sodium ion binding lithium ion binding response to stimulus
228129_at	-0.422	6.870	-2.564	2.140e-02	0.228	-3.414	SERBP1	SERPINE1 mRNA binding protein 1	1	-67646080	BE857133	26135	1p31	Hs.719078	22	RNA binding mRNA 3'-UTR binding protein binding nucleus cytoplasm regulation of mRNA stability perinuclear region of cytoplasm
218700_s_at	-0.271	3.285	-2.564	2.140e-02	0.228	-3.414	RAB7L1	RAB7, member RAS oncogene family-like 1	1	-204003737	BC002585	8934	1q32	Hs.115325	8	nucleotide binding GTPase activity protein binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport
200635_s_at	0.345	5.045	2.564	2.140e-02	0.228	-3.414	PTPRF	protein tyrosine phosphatase, receptor type, F	1	43769133	AU145351	5792	1p34	Hs.272062	49	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation cell adhesion transmembrane receptor protein tyrosine phosphatase signaling pathway membrane hydrolase activity	Cell adhesion molecules (CAMs) Adherens junction Insulin signaling pathway
1557609_s_at	-0.159	2.222	-2.564	2.141e-02	0.228	-3.414	TBC1D12	TBC1 domain family, member 12	10	96152175	AW188458	23232	10q23.33	Hs.500598	6	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
203642_s_at	0.362	4.977	2.564	2.142e-02	0.228	-3.414	COBLL1	COBL-like 1	2	-165249503	NM_014900	22837	2q24.3	Hs.470457	9
236311_at	0.430	4.700	2.564	2.143e-02	0.229	-3.415	LOH12CR2	loss of heterozygosity, 12, chromosomal region 2	12	-12399610	BE645784	503693	12p13.2	Hs.67553	2
206398_s_at	0.253	4.807	2.564	2.143e-02	0.229	-3.415	CD19	CD19 molecule	16	28850760	NM_001770	930	16p11.2	Hs.652262	49	receptor signaling protein activity protein binding plasma membrane integral to plasma membrane cellular defense response cell surface receptor linked signal transduction external side of plasma membrane B cell receptor signaling pathway	Hematopoietic cell lineage B cell receptor signaling pathway Primary immunodeficiency
223415_at	0.295	5.480	2.563	2.146e-02	0.229	-3.416	RPP25	ribonuclease P/MRP 25kDa subunit	15	-73034495	BC002497	54913	15q24.2	Hs.8562	6	RNA binding ribonuclease P activity protein binding nucleus tRNA processing hydrolase activity
235648_at	0.370	4.526	2.563	2.147e-02	0.229	-3.416	ZNF567	zinc finger protein 567	19	41872141	AA742659	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221016_s_at	0.365	5.139	2.563	2.147e-02	0.229	-3.417	TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	2	85214244	NM_031283	83439	2p11.2	Hs.516297	9	transcription factor activity nucleus chromatin organization beta-catenin binding determination of anterior/posterior axis, embryo regulation of Wnt receptor signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter, mitotic axial mesoderm morphogenesis stem cell differentiation	Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC)
205459_s_at	0.290	5.769	2.563	2.148e-02	0.229	-3.417	NPAS2	neuronal PAS domain protein 2	2	100803044	NM_002518	4862	2q11.2	Hs.156832 Hs.705895	23	transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding	Circadian rhythm - mammal
226682_at	-0.503	8.536	-2.562	2.148e-02	0.229	-3.417	RORA	RAR-related orphan receptor A	15	-58567776, -58567776, -58567776	AW006185	6095	15q22.2	Hs.560343 Hs.655155	33	transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding
228482_at	0.326	3.801	2.562	2.149e-02	0.229	-3.417	CDRT4	CMT1A duplicated region transcript 4	17	-15280062	AV702789	284040	17p12	Hs.164595	4
236430_at	0.322	3.811	2.562	2.149e-02	0.229	-3.417	TMED6	transmembrane emp24 protein transport domain containing 6	16	-67934660	AA708152	146456	16q22.1	Hs.658619	3	endoplasmic reticulum transport membrane integral to membrane
203068_at	-0.412	7.532	-2.562	2.149e-02	0.229	-3.417	KLHL21	kelch-like 21 (Drosophila)	1	-6573370	NM_014851	9903	1p36.31	Hs.7764	5	protein binding modification-dependent protein catabolic process
223262_s_at	-0.278	6.171	-2.562	2.152e-02	0.229	-3.418	FGFR1OP2	FGFR1 oncogene partner 2	12	26982582	AI738434	26127	12p11.23	Hs.591162	5	cytoplasm
232235_at	0.496	2.882	2.562	2.152e-02	0.229	-3.419	DSEL	dermatan sulfate epimerase-like	18	-63324798	AK021539	92126	18q22.1	Hs.124673	6	membrane integral to membrane
1555543_a_at	-0.408	5.470	-2.561	2.153e-02	0.229	-3.419	CLCC1	chloride channel CLIC-like 1	1	-109273652	AB052917	23155	1p13.3	Hs.658489	6	nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane
227728_at	-0.357	9.606	-2.561	2.154e-02	0.229	-3.419	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AA886888	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
235154_at	-0.227	6.452	-2.561	2.155e-02	0.229	-3.420	TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	10	7900678	BG250498	83860	10p15.1	Hs.527688 Hs.709995	12	DNA binding protein binding nucleus transcription factor TFIID complex zinc ion binding regulation of transcription metal ion binding maintenance of protein location in nucleus
242071_x_at	0.270	6.140	2.561	2.156e-02	0.229	-3.420	ITGA8	integrin, alpha 8	10	-15599093	BF446919	8516	10p13	Hs.171311	15	metanephros development receptor activity calcium ion binding protein binding cell-matrix adhesion integrin-mediated signaling pathway multicellular organismal development nervous system development memory integrin complex membrane integral to membrane cell-cell adhesion cell projection organization cell differentiation extracellular matrix organization positive regulation of transforming growth factor beta receptor signaling pathway inner ear morphogenesis apical part of cell	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
205993_s_at	0.207	5.742	2.561	2.156e-02	0.229	-3.420	TBX2	T-box 2	17	56832038	NM_005994	6909	17q23	Hs.531085	25	negative regulation of transcription from RNA polymerase II promoter heart morphogenesis transcription factor activity protein binding nucleus transcription factor complex multicellular organismal development muscle cell fate determination cell aging positive regulation of cell proliferation transcription repressor activity mammary gland development sequence-specific DNA binding cardiac muscle tissue development
227074_at	0.335	6.817	2.560	2.158e-02	0.229	-3.421	LOC100131564	hypothetical protein LOC100131564	1		AA524669	100131564	1p22.1	Hs.648647
201723_s_at	-0.406	8.049	-2.560	2.158e-02	0.229	-3.421	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	U41514	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
220348_at	-0.326	4.413	-2.560	2.158e-02	0.229	-3.421	KLHL29	kelch-like 29 (Drosophila)	2		NM_025067	114818	2p24.1	Hs.130593	5	protein binding
236418_at	0.295	3.931	2.560	2.158e-02	0.229	-3.421	TTLL10	tubulin tyrosine ligase-like family, member 10	1	1099148, 1104939	AW772075	254173	1p36.33	Hs.454835	4	tubulin-tyrosine ligase activity cytoplasm cytoskeleton microtubule protein modification process ligase activity protein polyglycylation protein-glycine ligase activity
223465_at	-0.457	6.401	-2.560	2.158e-02	0.229	-3.421	COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	5	-74702683, -74702683	BE967275	10087	5q13.3	Hs.270437	26	protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response
207317_s_at	0.659	10.568	2.560	2.158e-02	0.229	-3.421	CASQ2	calsequestrin 2 (cardiac muscle)	1	-116044148	NM_001232	845	1p13.3-p11	Hs.57975	37	calcium ion binding striated muscle contraction heart development sarcoplasmic reticulum lumen
204461_x_at	-0.434	7.606	-2.560	2.159e-02	0.229	-3.421	RAD1	RAD1 homolog (S. pombe)	5	-34941124, -34941122	NM_002853	5810	5p13.2	Hs.38114	44	cell cycle checkpoint DNA damage checkpoint damaged DNA binding protein binding nucleus DNA replication DNA repair response to DNA damage stimulus meiotic prophase I 3'-5' exonuclease activity 3'-5' exonuclease activity exodeoxyribonuclease III activity hydrolase activity
1553281_at	0.167	5.130	2.560	2.161e-02	0.229	-3.422	PLCXD2	phosphatidylinositol-specific phospholipase C, X domain containing 2	3	112876196, 112876196	NM_153268	257068	3q13.2	Hs.655022	2	phospholipase C activity signal transducer activity intracellular signaling cascade lipid catabolic process hydrolase activity
218160_at	0.335	10.633	2.559	2.162e-02	0.229	-3.423	NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	9	-123946158	NM_014222	4702	9q33.2-q34.11	Hs.495039	12	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
204428_s_at	0.373	5.478	2.559	2.163e-02	0.229	-3.423	LCAT	lecithin-cholesterol acyltransferase	16	-66531287	NM_000229	3931	16q22.1	Hs.387239	93	phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity protein binding extracellular space lipid metabolic process phospholipid metabolic process phosphatidylcholine biosynthetic process steroid metabolic process cholesterol metabolic process acyltransferase activity transferase activity apolipoprotein A-I binding high-density lipoprotein particle very-low-density lipoprotein particle remodeling high-density lipoprotein particle remodeling cholesterol esterification lipoprotein biosynthetic process cholesterol homeostasis reverse cholesterol transport response to copper ion response to glucocorticoid stimulus	Glycerophospholipid metabolism
211570_s_at	-0.325	6.748	-2.559	2.163e-02	0.229	-3.423	RAPSN	receptor-associated protein of the synapse	11	-47415890	BC004196	5913	11p11.2-p11.1	Hs.81218	32	protein binding cytoplasm Golgi apparatus cytoskeleton plasma membrane synaptic transmission zinc ion binding cell junction neuromuscular junction acetylcholine receptor binding postsynaptic membrane metal ion binding
201508_at	0.361	5.355	2.559	2.164e-02	0.229	-3.424	IGFBP4	insulin-like growth factor binding protein 4	17	35853201	NM_001552	3487	17q12-q21.1	Hs.462998	55	skeletal system development regulation of cell growth insulin-like growth factor binding extracellular region extracellular space DNA metabolic process inflammatory response signal transduction cell proliferation
200849_s_at	-0.381	9.078	-2.559	2.164e-02	0.229	-3.424	AHCYL1	adenosylhomocysteinase-like 1	1	110328830	AI589266	10768	1p13.2	Hs.705418	15	adenosylhomocysteinase activity binding endoplasmic reticulum one-carbon metabolic process metabolic process hydrolase activity	Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways
202187_s_at	-0.388	8.106	-2.558	2.165e-02	0.229	-3.424	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha isoform	1	210525501	NM_006243	5525	1q32.2-q32.3	Hs.716433	41	protein phosphatase type 2A complex chromosome, centromeric region protein binding nucleus cytoplasm signal transduction protein phosphatase type 2A regulator activity	Wnt signaling pathway
201881_s_at	-0.399	7.217	-2.558	2.165e-02	0.229	-3.424	ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	15	70553720	NM_005744	25820	15q24	Hs.268787	11	ubiquitin ligase complex protein binding cytoplasm ubiquitin-dependent protein catabolic process zinc ion binding small conjugating protein ligase activity metal ion binding
211726_s_at	0.685	6.169	2.558	2.167e-02	0.229	-3.425	FMO2	flavin containing monooxygenase 2 (non-functional)	1	169421011	BC005894	2327	1q23-q25	Hs.144912	18	magnesium ion binding monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome oxygen and reactive oxygen species metabolic process membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction	Drug metabolism - cytochrome P450
222847_s_at	-0.313	5.277	-2.558	2.167e-02	0.229	-3.425	EGLN3	egl nine homolog 3 (C. elegans)	14	-33463171	AI378406	112399	14q13.1	Hs.135507	26	iron ion binding protein binding nucleus cytoplasm apoptosis oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction	Pathways in cancer Renal cell carcinoma
220532_s_at	0.582	4.994	2.558	2.167e-02	0.229	-3.425	TMEM176B	transmembrane protein 176B	7	-150119308, -150119308, -150119308	NM_014020	28959	7q36.1	Hs.647090 Hs.709505	7	nucleus organ morphogenesis membrane integral to membrane cell differentiation
233555_s_at	0.325	4.344	2.558	2.167e-02	0.229	-3.425	SULF2	sulfatase 2	20	-45719556, -45719556	AL034418	55959	20q12-q13.2	Hs.162016	16	arylsulfatase activity calcium ion binding extracellular space endoplasmic reticulum Golgi apparatus Golgi stack metabolic process cell surface hydrolase activity heparan sulfate proteoglycan metabolic process
225011_at	-0.277	10.432	-2.558	2.169e-02	0.229	-3.426	PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	3	-48763096	AK026351	5576	3p21.3-p21.2	Hs.631923	81	nucleotide binding regulation of protein amino acid phosphorylation membrane fraction cytoplasm plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase regulator activity hormone-mediated signaling cAMP binding	Apoptosis Insulin signaling pathway
201141_at	0.786	8.268	2.557	2.170e-02	0.229	-3.426	GPNMB	glycoprotein (transmembrane) nmb	7	23252840	NM_002510	10457	7p15	Hs.190495	24	osteoblast differentiation integrin binding integral to plasma membrane cell adhesion heparin binding negative regulation of cell proliferation membrane cytoplasmic membrane-bounded vesicle bone mineralization melanosome
213694_at	-0.440	6.555	-2.557	2.171e-02	0.229	-3.427	RSBN1	round spermatid basic protein 1	1	-114105976	AW027347	54665	1p13.2	Hs.486285	6	protein binding nucleus
202675_at	0.321	10.423	2.557	2.171e-02	0.229	-3.427	SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	1	-17217811	NM_003000	6390	1p36.1-p35	Hs.465924	62	iron ion binding protein binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane tricarboxylic acid cycle transport succinate dehydrogenase (ubiquinone) activity electron carrier activity membrane oxidoreductase activity electron transport chain metal ion binding 2 iron, 2 sulfur cluster binding 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding	Citrate cycle (TCA cycle) Oxidative phosphorylation Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
237847_at	0.217	5.575	2.557	2.173e-02	0.229	-3.427	NTN1	netrin 1	17	8865583	BF058964	9423	17p13-p12	Hs.660885	29	neuron migration protein binding extracellular region basement membrane cytoplasm apoptosis axon guidance positive regulation of cell proliferation regulation of cell migration negative regulation of axon extension mammary gland development establishment of nucleus localization positive regulation of axon extension	Axon guidance
226112_at	-0.506	9.498	-2.557	2.173e-02	0.229	-3.428	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	4	-52581617	AI678717	6443	4q12	Hs.438953	28	cytoplasm cytoskeleton plasma membrane integral to plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
202354_s_at	0.222	5.134	2.556	2.174e-02	0.229	-3.428	GTF2F1	general transcription factor IIF, polypeptide 1, 74kDa	19	-6330579	AW190445	2962	19p13.3	Hs.68257	79	nuclear mRNA splicing, via spliceosome DNA binding transcription coactivator activity catalytic activity nucleus nucleoplasm transcription factor TFIIF complex transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter transcription factor binding general RNA polymerase II transcription factor activity positive regulation of transcription	Basal transcription factors
206469_x_at	0.232	6.145	2.556	2.174e-02	0.229	-3.428	AKR7A3	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	1	-19481643	NM_012067	22977	1p36.13	Hs.6980	6	aldo-keto reductase activity cytoplasm cytosol cellular aldehyde metabolic process electron carrier activity oxidoreductase activity oxidation reduction
208962_s_at	0.341	4.666	2.556	2.175e-02	0.229	-3.428	FADS1	fatty acid desaturase 1	11	-61323678	BE540552	3992	11q12.2-q13.1	Hs.503546	30	C-5 sterol desaturase activity protein binding membrane fraction endoplasmic reticulum microsome unsaturated fatty acid biosynthetic process transport cell-cell signaling phospholipid biosynthetic process cellular response to starvation membrane integral to membrane oxidoreductase activity heme binding electron transport chain regulation of transcription regulation of cell differentiation icosanoid biosynthetic process	Biosynthesis of unsaturated fatty acids
223119_s_at	-0.454	8.043	-2.556	2.177e-02	0.230	-3.429	USP47	ubiquitin specific peptidase 47	11	11819545	BC000226	55031	11p15.3	Hs.577256	12	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
213001_at	-0.532	7.322	-2.556	2.177e-02	0.230	-3.429	ANGPTL2	angiopoietin-like 2	9	-128889448	AF007150	23452	9q34	Hs.653262	11	receptor binding extracellular region extracellular space signal transduction multicellular organismal development
214444_s_at	0.250	5.070	2.555	2.178e-02	0.230	-3.430	PVR	poliovirus receptor	19	49838937, 49838937	NM_006505	5817	19q13.2	Hs.171844	46	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target receptor activity extracellular region extracellular space cytoplasm plasma membrane plasma membrane cell adhesion cell surface integral to membrane susceptibility to natural killer cell mediated cytotoxicity interspecies interaction between organisms cell adhesion molecule binding susceptibility to T cell mediated cytotoxicity	Cell adhesion molecules (CAMs)
219239_s_at	-0.406	5.272	-2.555	2.179e-02	0.230	-3.430	ZNF654	zinc finger protein 654	3	88270951	NM_018293	55279	3p11.1	Hs.591650 Hs.661116	1	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1557136_at	0.247	4.183	2.555	2.179e-02	0.230	-3.430	ATP13A4	ATPase type 13A4	3	-194602559	BG059633	84239	3q29	Hs.674423	4	nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity
218878_s_at	-0.530	7.025	-2.555	2.180e-02	0.230	-3.430	SIRT1	sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)	10	69314432, 69314944	NM_012238	23411	10q21.3	Hs.369779	128	ovulation from ovarian follicle p53 binding transcription corepressor activity NAD+ ADP-ribosyltransferase activity nucleus nuclear envelope nucleolus cytoplasm DNA replication DNA repair establishment of chromatin silencing maintenance of chromatin silencing protein amino acid ADP-ribosylation triglyceride mobilization response to DNA damage stimulus multicellular organismal development spermatogenesis muscle organ development cell aging protein C-terminus binding zinc ion binding cellular response to starvation negative regulation of transcription histone deacetylation PML body hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity deacetylase activity protein domain specific binding cell differentiation positive regulation of chromatin silencing regulation of protein import into nucleus, translocation regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor peptidyl-lysine deacetylation regulation of cell proliferation histone binding identical protein binding regulation of apoptosis negative regulation of transcription factor activity negative regulation of DNA damage response, signal transduction by p53 class mediator interspecies interaction between organisms negative regulation of fat cell differentiation positive regulation of anti-apoptosis metal ion binding white fat cell differentiation negative regulation of helicase activity NAD binding
1565661_x_at	0.281	5.480	2.555	2.181e-02	0.230	-3.431	FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	19	-5781636	BC040472	2528	19p13.3	Hs.631846 Hs.705615	19	Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity	Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
212950_at	0.364	8.072	2.555	2.182e-02	0.230	-3.431	GPR116	G protein-coupled receptor 116	6	-46928203, -46928203	BF941499	221395	6p12.3	Hs.362806	18	G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
209949_at	0.169	4.142	2.555	2.182e-02	0.230	-3.431	NCF2	neutrophil cytosolic factor 2	1	-181791319, -181791319	BC001606	4688	1q25	Hs.587558	71	acrosomal vesicle nucleolus cytoplasm cellular defense response protein C-terminus binding electron carrier activity superoxide-generating NADPH oxidase activity superoxide anion generation NADPH oxidase complex innate immune response respiratory burst Rac GTPase binding	Leukocyte transendothelial migration
243296_at	-0.634	5.401	-2.554	2.183e-02	0.230	-3.431	NAMPT	nicotinamide phosphoribosyltransferase	7	-105675967	AA873350	10135	7q22.3	Hs.489615	98	cytokine activity cytoplasm cytosol signal transduction cell-cell signaling positive regulation of cell proliferation NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity	Nicotinate and nicotinamide metabolism
203580_s_at	-0.324	8.015	-2.554	2.183e-02	0.230	-3.431	SLC7A6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6	16	66855923	NM_003983	9057	16q22.1	Hs.653193 Hs.709557	6	plasma membrane integral to plasma membrane protein complex assembly cellular amino acid metabolic process transport amino acid transport amino acid transmembrane transporter activity antiporter activity
204069_at	-0.548	4.800	-2.554	2.183e-02	0.230	-3.432	MEIS1	Meis homeobox 1	2	66516035	NM_002398	4211	2p14-p13	Hs.526754 Hs.603755	42	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding
211194_s_at	-0.318	4.551	-2.554	2.185e-02	0.230	-3.432	TP63	tumor protein p63	3	190831909, 190831909, 190990142, 190990142	AB010153	8626	3q28	Hs.137569	238	response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization
212366_at	-0.327	5.848	-2.554	2.185e-02	0.230	-3.432	ZNF292	zinc finger protein 292	6	87921987	BF223237	23036	6q14.3	Hs.485892 Hs.656621	7	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
214503_x_at	0.213	4.075	2.554	2.185e-02	0.230	-3.432	GPR135	G protein-coupled receptor 135	14	-58999992	NM_022571	64582	14q23.1	Hs.647573	5	receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
221538_s_at	0.405	6.832	2.554	2.185e-02	0.230	-3.432	PLXNA1	plexin A1	3	128190191	AL136663	5361	3q21.3	Hs.432329	18	receptor activity protein binding cellular_component intracellular membrane fraction signal transduction multicellular organismal development membrane integral to membrane semaphorin receptor activity	Axon guidance
207987_s_at	0.247	2.780	2.554	2.186e-02	0.230	-3.433	GNRH1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)	8	-25332690	NM_000825	2796	8p21-p11.2	Hs.82963	66	gonadotropin hormone-releasing hormone activity extracellular region soluble fraction signal transduction cell-cell signaling multicellular organismal development negative regulation of cell proliferation regulation of gene expression response to ethanol response to steroid hormone stimulus	GnRH signaling pathway
202920_at	-0.445	9.060	-2.554	2.186e-02	0.230	-3.433	ANK2	ankyrin 2, neuronal	4	113958687, 114190233	BF726212	287	4q25-q27	Hs.620557	39	protein binding cytoplasm cytoskeleton plasma membrane signal transduction basolateral plasma membrane apical plasma membrane M band
219913_s_at	-0.424	6.603	-2.554	2.186e-02	0.230	-3.433	CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)	20	-19963011	NM_016652	51340	20p11.2	Hs.171342	7	spliceosome assembly RNA binding intracellular nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing nuclear speck
202611_s_at	-0.634	6.688	-2.553	2.189e-02	0.230	-3.434	MED14	mediator complex subunit 14	X	-40393738	AI971089	9282	Xp11.4-p11.2	Hs.407604	33	receptor activity protein binding nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
213342_at	0.256	5.299	2.553	2.191e-02	0.230	-3.435	YAP1	Yes-associated protein 1, 65kDa	11	101486419	AI745185	10413	11q13	Hs.503692	46	protein binding
219493_at	0.400	4.573	2.552	2.192e-02	0.230	-3.435	SHCBP1	SHC SH2-domain binding protein 1	16	-45171968	NM_024745	79801	16q11.2	Hs.123253	17	protein binding SH2 domain binding
206774_at	0.359	5.197	2.552	2.192e-02	0.230	-3.435	FRMPD1	FERM and PDZ domain containing 1	9	37641051	NM_014907	22844	9p13.2	Hs.163990	4	protein binding cytoplasm cytosol cytoskeleton plasma membrane
1569843_at	0.309	2.590	2.552	2.193e-02	0.230	-3.435	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	7	95239753	BC012504	1780	7q21.3-q22.1	Hs.440364	17	microtubule motor activity protein binding cytoplasmic dynein complex microtubule microtubule binding vesicle transport along microtubule perinuclear region of cytoplasm
230536_at	0.170	4.133	2.552	2.193e-02	0.230	-3.435	PBX4	pre-B-cell leukemia homeobox 4	19	-19533521	AJ300182	80714	19p12	Hs.466257	7	XY body transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter transcription activator activity sequence-specific DNA binding
244861_at	0.218	6.374	2.552	2.193e-02	0.230	-3.436	ZNF527	zinc finger protein 527	19	42553898	AI679883	84503	19q13.1	Hs.590940	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
212719_at	-0.400	3.788	-2.552	2.195e-02	0.230	-3.436	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	18	58533713	AB011178	23239	18q21.33	Hs.465337	13	protein serine/threonine phosphatase activity protein binding nucleus cytoplasm cytosol apoptosis membrane hydrolase activity manganese ion binding metal ion binding
34210_at	0.373	3.347	2.552	2.195e-02	0.230	-3.436	CD52	CD52 molecule	1	26516997	N90866	1043	1p36	Hs.276770	27	membrane fraction plasma membrane integral to plasma membrane elevation of cytosolic calcium ion concentration anchored to membrane respiratory burst
1559399_s_at	0.507	4.963	2.552	2.195e-02	0.230	-3.436	ZCCHC10	zinc finger, CCHC domain containing 10	5	-132360575	BC015986	54819	5q31.1	Hs.29700	5	nucleic acid binding zinc ion binding metal ion binding
212373_at	-0.475	5.730	-2.552	2.195e-02	0.230	-3.437	FEM1B	fem-1 homolog b (C. elegans)	15	66357194	AW139179	10116	15q22	Hs.362733	9	ubiquitin-protein ligase activity death receptor binding death receptor binding cellular_component cytoplasm induction of apoptosis modification-dependent protein catabolic process regulation of apoptosis regulation of ubiquitin-protein ligase activity
208934_s_at	0.250	5.451	2.551	2.197e-02	0.230	-3.437	LGALS8	lectin, galactoside-binding, soluble, 8	1	234748187, 234753361, 234753699	AF342815	3964	1q42-q43	Hs.4082 Hs.708114	29	sugar binding extracellular space cytoplasm
242294_at	-0.354	5.493	-2.550	2.200e-02	0.230	-3.439	FBXO45	F-box protein 45	3	197780121	AA973128	200933	3q29	Hs.169815	2	modification-dependent protein catabolic process
221785_at	0.282	5.425	2.550	2.203e-02	0.231	-3.440	WIZ	widely interspaced zinc finger motifs	19	-15393317	AI828531	58525	19p13.1	Hs.442138	6	intracellular nucleus zinc ion binding metal ion binding
228709_at	-0.340	4.716	-2.549	2.207e-02	0.231	-3.441	TPR	translocated promoter region (to activated MET oncogene)	1	-184547408	BF109993	7175	1q25	Hs.279640	30	nucleotide binding kinetochore serine-tRNA ligase activity protein binding ATP binding nucleus nuclear pore nucleoplasm cytoplasm translation seryl-tRNA aminoacylation protein import into nucleus mitotic cell cycle spindle assembly checkpoint protein transport membrane mRNA transport intracellular protein transmembrane transport	Pathways in cancer Thyroid cancer
219024_at	-0.444	6.599	-2.549	2.207e-02	0.231	-3.441	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	10	124124209, 124141832	NM_021622	59338	10q26.13	Hs.643512	16	phospholipid binding cellular_component nucleus cytoplasm plasma membrane biological_process
222875_at	0.288	6.775	2.549	2.207e-02	0.231	-3.441	DHX33	DEAH (Asp-Glu-Ala-His) box polypeptide 33	17	-5286314	AI720923	56919	17p13.2	Hs.250456	4	nucleotide binding nucleic acid binding helicase activity ATP binding nucleus nucleolus ATP-dependent helicase activity hydrolase activity
203046_s_at	0.244	4.958	2.549	2.208e-02	0.231	-3.442	TIMELESS	timeless homolog (Drosophila)	12	-55096424	NM_003920	8914	12q12-q13	Hs.118631	28	nuclear chromatin morphogenesis of an epithelium protein binding nucleus response to DNA damage stimulus cell cycle mitosis multicellular organismal development circadian rhythm detection of abiotic stimulus negative regulation of transcription regulation of S phase regulation of cell proliferation cell division
218393_s_at	-0.282	6.287	-2.548	2.210e-02	0.231	-3.442	SMU1	smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)	9	-33031849	NM_018225	55234	9p12	Hs.655351	10	nucleus cytoplasm
1555214_a_at	0.225	3.808	2.548	2.210e-02	0.231	-3.443	CLEC7A	C-type lectin domain family 7, member A	12	-10171188, -10160646	AF400602	64581	12p13.2	Hs.143929	30	binding sugar binding cytoplasm phagocytosis, recognition inflammatory response pattern recognition receptor activity carbohydrate mediated signaling membrane integral to membrane T cell activation MHC protein binding defense response to protozoan innate immune response
213514_s_at	-0.257	6.710	-2.548	2.211e-02	0.231	-3.443	DIAPH1	diaphanous homolog 1 (Drosophila)	5	-140874771	AU158818	1729	5q31	Hs.529451	33	actin binding receptor binding cytoplasm cytoskeleton plasma membrane sensory perception of sound cellular component organization Rho GTPase binding actin cytoskeleton organization ruffle membrane cell projection	Focal adhesion Regulation of actin cytoskeleton
212932_at	-0.270	5.754	-2.548	2.212e-02	0.231	-3.443	RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	2	135526322	AK022494	22930	2q21.3	Hs.306327	17	GTPase activator activity Rab GTPase activator activity soluble fraction cytoplasm Rab GTPase binding regulation of GTPase activity
227112_at	-0.436	7.923	-2.548	2.212e-02	0.231	-3.443	TMCC1	transmembrane and coiled-coil domain family 1	3	-130849324, -130849324	AW270037	23023	3q22.1	Hs.477547 Hs.709936	6	membrane integral to membrane
208731_at	-0.450	9.818	-2.548	2.212e-02	0.231	-3.444	RAB2A	RAB2A, member RAS oncogene family	8	61592112	AU158062	5862	8q12.1	Hs.369017	19	nucleotide binding GTPase activity GTP binding endoplasmic reticulum Golgi apparatus ER to Golgi vesicle-mediated transport small GTPase mediated signal transduction protein transport membrane vesicle-mediated transport melanosome
210839_s_at	0.329	5.512	2.547	2.214e-02	0.231	-3.444	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2	8	-120638500, -120638499	D45421	5168	8q24.1	Hs.190977	47	nucleic acid binding phosphodiesterase I activity nucleotide diphosphatase activity extracellular region plasma membrane integral to plasma membrane phosphate metabolic process cell motion chemotaxis G-protein coupled receptor protein signaling pathway transcription factor binding metabolic process lipid catabolic process hydrolase activity metal ion binding alkylglycerophosphoethanolamine phosphodiesterase activity	Ether lipid metabolism
204711_at	0.219	5.867	2.547	2.214e-02	0.231	-3.444	KIAA0753	KIAA0753	17	-6422368	NM_014804	9851	17p13.2-p13.1	Hs.28070	3
65591_at	-0.247	6.971	-2.547	2.215e-02	0.231	-3.445	WDR48	WD repeat domain 48	3	39068510	N64681	57599	3p21.33	Hs.109778	9	protein binding nucleus cytoplasm lysosome protein deubiquitination modification-dependent protein catabolic process interspecies interaction between organisms
200824_at	0.309	8.832	2.547	2.215e-02	0.231	-3.445	GSTP1	glutathione S-transferase pi 1	11	67107641	NM_000852	2950	11q13	Hs.523836	788	glutathione transferase activity protein binding cytoplasm anti-apoptosis central nervous system development metabolic process transferase activity	Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Pathways in cancer Prostate cancer
230273_at	0.223	5.960	2.546	2.219e-02	0.232	-3.446	C6orf165	chromosome 6 open reading frame 165	6	88174439, 88174449	AI798983	154313	6q15	Hs.82921	5
230694_at	0.243	4.101	2.546	2.219e-02	0.232	-3.446	SLC35E2	solute carrier family 35, member E2	1	-1653540	AI340341	9906	1p36.33	Hs.707620 Hs.718607	3
218403_at	-0.262	9.088	-2.546	2.219e-02	0.232	-3.446	TRIAP1	TP53 regulated inhibitor of apoptosis 1	12	-119366146	NM_016399	51499	12q24.31	Hs.69499	7	protein binding cytoplasm mitochondrion apoptosis anti-apoptosis DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest caspase inhibitor activity perinuclear region of cytoplasm
233885_at	0.250	4.876	2.546	2.220e-02	0.232	-3.447	SNX26	sorting nexin 26	19	40958315	AC002398	115703	19q13.12	Hs.515364	13	GTPase activator activity protein binding intracellular signal transduction protein transport phosphoinositide binding
223345_at	0.235	5.606	2.546	2.221e-02	0.232	-3.447	HDAC8	histone deacetylase 8	X	-71466090	AF230097	55869	Xq13	Hs.310536	23	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter nuclear chromosome histone deacetylase activity nucleus cytoplasm chromatin assembly or disassembly transcription factor binding chromatin modification histone deacetylation hydrolase activity regulation of transcription
228199_at	0.250	5.370	2.546	2.221e-02	0.232	-3.447	LOC729234	fumarylacetoacetate hydrolase domain containing 2 pseudogene	2	96040025	AI271418	729234	2q11.1	Hs.348629	2
230281_at	0.399	5.406	2.545	2.224e-02	0.232	-3.448	C16orf46	chromosome 16 open reading frame 46	16	-79652085, -79644602	AI921002	123775	16q23.2	Hs.658684	4
238574_at	0.306	6.272	2.545	2.224e-02	0.232	-3.448	MCART1	mitochondrial carrier triple repeat 1	9	-37877593, -37867571	BF724944	92014	9p13.3-p12	Hs.645492 Hs.719380	6	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
221436_s_at	0.213	4.884	2.545	2.224e-02	0.232	-3.448	CDCA3	cell division cycle associated 3	12	-6828232	NM_031299	83461	12p13	Hs.524216	8	molecular_function cellular_component cytoplasm cytosol cell cycle mitosis biological_process modification-dependent protein catabolic process cell division
237884_x_at	-0.525	2.725	-2.545	2.225e-02	0.232	-3.449	TRPM7	transient receptor potential cation channel, subfamily M, member 7	15	-48639781	BF939551	54822	15q21	Hs.512894	45	nucleotide binding ruffle actin binding protein serine/threonine kinase activity ion channel activity calcium channel activity calcium ion binding protein binding ATP binding plasma membrane ion transport calcium ion transport zinc ion binding integral to membrane kinase activity calcium-dependent cell-matrix adhesion transferase activity myosin binding actomyosin structure organization protein amino acid autophosphorylation
205110_s_at	-0.635	8.152	-2.545	2.226e-02	0.232	-3.449	FGF13	fibroblast growth factor 13	X	-137541401, -137541401, -137541401, -137541401	NM_004114	2258	Xq26.3	Hs.6540 Hs.711551	13	MAPKKK cascade protein binding nucleus cytoplasm signal transduction cell-cell signaling nervous system development growth factor activity protein kinase activator activity	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
201632_at	-0.235	7.777	-2.545	2.226e-02	0.232	-3.449	EIF2B1	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	12	-122671522	NM_001414	1967	12q24.31	Hs.716475	26	translation initiation factor activity guanyl-nucleotide exchange factor activity protein binding membrane fraction cytoplasm eukaryotic translation initiation factor 2B complex plasma membrane translational initiation response to heat response to heat response to glucose stimulus oligodendrocyte development response to peptide hormone stimulus cellular metabolic process cellular response to stimulus
218361_at	-0.359	7.108	-2.544	2.227e-02	0.232	-3.450	GOLPH3L	golgi phosphoprotein 3-like	1	-148885324	NM_018178	55204	1q21.3	Hs.646007	4	cytoplasm Golgi apparatus membrane
228073_at	0.314	5.819	2.544	2.227e-02	0.232	-3.450	NANP	N-acetylneuraminic acid phosphatase	20	-25541574	AI146450	140838	20p11.1	Hs.143137 Hs.606268	7	magnesium ion binding cellular_component carbohydrate metabolic process metabolic process phosphoglycolate phosphatase activity hydrolase activity N-acetylneuraminate biosynthetic process N-acylneuraminate-9-phosphatase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
227888_at	0.183	5.023	2.544	2.228e-02	0.232	-3.450	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	20	-17542322	AA534989	6238	20p12	Hs.472213	19	receptor activity endoplasmic reticulum ribosome translation signal transduction protein transport membrane integral to membrane integral to endoplasmic reticulum membrane intracellular protein transmembrane transport
202754_at	-0.396	8.357	-2.544	2.230e-02	0.232	-3.451	R3HDM1	R3H domain containing 1	2	136005552	NM_015361	23518	2q21.3	Hs.412462	8	nucleic acid binding
205376_at	-0.838	4.882	-2.543	2.231e-02	0.232	-3.451	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	4	-143168631	NM_003866	8821	4q31.21	Hs.658245	9	signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
202235_at	-0.413	7.042	-2.543	2.231e-02	0.232	-3.451	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	BF511091	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
203360_s_at	-0.445	6.026	-2.543	2.231e-02	0.232	-3.451	MYCBP	c-myc binding protein	1	-39101222	D50692	26292	1p33-p32.2	Hs.591506	12	transcription coactivator activity protein binding nucleus cytoplasm mitochondrion spermatogenesis regulation of transcription
210290_at	0.247	4.178	2.543	2.232e-02	0.232	-3.451	ZNF174	zinc finger protein 174	16	3391190, 3391190	BC001161	7727	16p13.3	Hs.155204	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding intracellular nucleus nucleolus cytoplasm cytoskeleton regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224638_at	0.203	5.462	2.543	2.232e-02	0.232	-3.452	UNQ1887	signal peptide peptidase 3	12	-119685417	AI338356	121665	12q24.31	Hs.507087 Hs.683964	12	aspartic-type endopeptidase activity peptidase activity membrane integral to membrane
227013_at	-0.417	8.565	-2.543	2.233e-02	0.232	-3.452	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	13	-20445175	AI535735	26524	13q11-q12	Hs.78960	17	G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding spindle pole protein serine/threonine kinase activity ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation cell cycle mitosis protein kinase cascade hormone-mediated signaling transferase activity negative regulation of cyclin-dependent protein kinase activity cell division
212371_at	-0.316	8.017	-2.543	2.234e-02	0.232	-3.452	PPPDE1	PPPDE peptidase domain containing 1	1	242882974	AL049397	51029	1q44	Hs.498317	5
223990_at	0.284	6.135	2.543	2.234e-02	0.232	-3.452	C4orf17	chromosome 4 open reading frame 17	4	100651222	AL136838	84103	4q23	Hs.97501	6
214310_s_at	0.338	5.195	2.542	2.235e-02	0.232	-3.453	ZFPL1	zinc finger protein-like 1	11	64608269	AI767884	7542	11q13	Hs.714995 Hs.98170	8	DNA binding protein binding nucleus Golgi apparatus zinc ion binding membrane integral to membrane vesicle-mediated transport regulation of transcription metal ion binding
205054_at	-0.183	13.427	-2.542	2.235e-02	0.232	-3.453	NEB	nebulin	2	-152050098	NM_004543	4703	2q22	Hs.588655	32	actin binding protein binding cytoplasm somatic muscle development structural constituent of muscle actin cytoskeleton sarcomere Z disc regulation of actin filament length
222569_at	-0.468	6.279	-2.542	2.236e-02	0.232	-3.453	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1	2	128565223, 128565251	AU153746	56886	2q14.3	Hs.598715 Hs.719174	10	UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding
226598_s_at	0.242	6.908	2.542	2.236e-02	0.232	-3.453	GTPBP5	GTP binding protein 5 (putative)	20	60191475	AK001603	26164	20q13.33	Hs.340636	6	nucleotide binding GTP binding intracellular mitochondrion ribosome biogenesis
209542_x_at	0.421	6.469	2.542	2.237e-02	0.232	-3.453	IGF1	insulin-like growth factor 1 (somatomedin C)	12	-101335583, -101313774, -101313774	M29644	3479	12q22-q23	Hs.160562	714	skeletal system development osteoblast differentiation insulin receptor binding insulin-like growth factor receptor binding insulin-like growth factor receptor binding hormone activity hormone activity protein binding extracellular region extracellular region extracellular region DNA replication anti-apoptosis cell motion signal transduction Ras protein signal transduction nervous system development muscle organ development growth factor activity positive regulation of cell proliferation glycolate metabolic process organ morphogenesis glial cell differentiation positive regulation of phosphoinositide 3-kinase cascade satellite cell maintenance involved in skeletal muscle regeneration muscle hypertrophy myotube cell development positive regulation of smooth muscle cell migration insulin-like growth factor binding protein complex positive regulation of granule cell precursor proliferation water homeostasis proteoglycan biosynthetic process mammary gland development platelet alpha granule lumen regulation of steroid hormone receptor signaling pathway negative regulation of smooth muscle cell apoptosis regulation of multicellular organism growth positive regulation of tyrosine phosphorylation of Stat5 protein positive regulation of gene-specific transcription positive regulation of insulin-like growth factor receptor signaling pathway myoblast differentiation positive regulation of DNA replication positive regulation of DNA replication positive regulation of glycolysis positive regulation of mitosis positive regulation of transcription from RNA polymerase II promoter positive regulation of Ras protein signal transduction phosphoinositide-mediated signaling positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation branching morphogenesis of a tube chondroitin sulfate proteoglycan biosynthetic process positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation regulation of protein metabolic process myoblast proliferation	p53 signaling pathway mTOR signaling pathway Focal adhesion Long-term depression Pathways in cancer Glioma Prostate cancer Melanoma Hypertrophic cardiomyopathy (HCM)
1566271_x_at	-0.198	3.442	-2.542	2.237e-02	0.232	-3.453	GARNL1	GTPase activating Rap/RanGAP domain-like 1	14	-35077308	AF085938	253959	14q13.2	Hs.113150	10	GTPase activator activity intracellular nucleus cytoplasm mitochondrion regulation of small GTPase mediated signal transduction
224592_x_at	-0.343	9.623	-2.541	2.240e-02	0.232	-3.455	HP1BP3	heterochromatin protein 1, binding protein 3	1	-20941757	BG483966	50809	1p36.12	Hs.142442	3	nucleosome DNA binding nucleus chromosome nucleosome assembly
218228_s_at	-0.456	7.872	-2.541	2.242e-02	0.232	-3.456	TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	10	93548130	NM_025235	80351	10q23.3	Hs.329327	15	pericentriolar material nuclear chromosome, telomeric region NAD+ ADP-ribosyltransferase activity nucleus nuclear envelope chromosome cytoplasm microsome Golgi apparatus protein amino acid ADP-ribosylation membrane transferase activity, transferring glycosyl groups positive regulation of telomere maintenance via telomerase regulation of multicellular organism growth perinuclear region of cytoplasm protein localization to telomere
223113_at	0.317	6.164	2.540	2.246e-02	0.233	-3.457	TMEM138	transmembrane protein 138	11	60886431	AF151030	51524	11q12.2	Hs.406530	3	membrane integral to membrane
235338_s_at	-0.239	3.808	-2.540	2.246e-02	0.233	-3.457	SETDB2	SET domain, bifurcated 2	13	48916429, 48923688	W65369	83852	13q14	Hs.631789 Hs.633823	6	DNA binding nucleus methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity	Lysine degradation
210148_at	-0.836	4.518	-2.540	2.246e-02	0.233	-3.457	HIPK3	homeodomain interacting protein kinase 3	11	33235743	AF305239	10114	11p13	Hs.201918	14	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm apoptosis anti-apoptosis transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation negative regulation of JUN kinase activity regulation of transcription
241150_at	0.319	4.800	2.540	2.247e-02	0.233	-3.457	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	9	130354686	AI668588	6709	9q33-q34	Hs.372331	70	actin binding structural constituent of cytoskeleton calcium ion binding calmodulin binding membrane fraction cytoplasm cytosol cytoskeleton cell cortex spectrin actin filament capping	Tight junction
236655_at	-0.417	4.874	-2.539	2.249e-02	0.233	-3.458	TPD52	tumor protein D52	8	-81109659, -81109659	AI632972	7163	8q21	Hs.368433	27	calcium ion binding cytoplasm endoplasmic reticulum anatomical structure morphogenesis B cell differentiation protein homodimerization activity secretion protein heterodimerization activity perinuclear region of cytoplasm
210661_at	-0.329	2.351	-2.539	2.249e-02	0.233	-3.458	GLRA3	glycine receptor, alpha 3	4	-175799772	U93917	8001	4q33-q34	Hs.413099	8	ion channel activity extracellular ligand-gated ion channel activity plasma membrane ion transport chloride transport synaptic transmission integral to membrane extracellular-glycine-gated chloride channel activity cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
209546_s_at	0.256	6.253	2.539	2.249e-02	0.233	-3.459	APOL1	apolipoprotein L, 1	22	34979062	AF323540	8542	22q13.1	Hs.114309	27	chloride channel activity protein binding extracellular region extracellular space lipid metabolic process chloride transport lipid transport steroid metabolic process cholesterol metabolic process lipid binding cytolysis intrinsic to membrane killing of cells of another organism very-low-density lipoprotein particle high-density lipoprotein particle lipoprotein metabolic process innate immune response
200897_s_at	-0.484	10.525	-2.539	2.249e-02	0.233	-3.459	PALLD	palladin, cytoskeletal associated protein	4	169654791	NM_016081	23022	4q32.3	Hs.151220	40	actin binding protein binding nucleus cytoplasm cytoskeleton actin filament cytoskeleton organization muscle alpha-actinin binding
209653_at	-0.519	5.423	-2.539	2.249e-02	0.233	-3.459	KPNA4	karyopherin alpha 4 (importin alpha 3)	3	-161700655	U93240	3840	3q25.33	Hs.715552	53	protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity
202677_at	0.304	8.348	2.539	2.250e-02	0.233	-3.459	RASA1	RAS p21 protein activator (GTPase activating protein) 1	5	86599906, 86600521	NM_002890	5921	5q13.3	Hs.664080	126	cytokinesis vasculogenesis ruffle glycoprotein binding negative regulation of cell-matrix adhesion Ras GTPase activator activity receptor binding intracellular cytoplasm plasma membrane negative regulation of cell adhesion intracellular signaling cascade regulation of cell shape embryonic development potassium channel inhibitor activity regulation of actin filament polymerization negative regulation of neuron apoptosis positive regulation of anti-apoptosis GTPase binding regulation of small GTPase mediated signal transduction regulation of RNA metabolic process	MAPK signaling pathway Axon guidance
226015_at	0.227	6.752	2.539	2.250e-02	0.233	-3.459	ZNF12	zinc finger protein 12	7	-6694588	AI865669	7559	7p22.1	Hs.431471	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222957_at	0.198	6.719	2.539	2.250e-02	0.233	-3.459	NEU4	sialidase 4	2	242400745	AK025617	129807	2q37.3	Hs.551747	12	exo-alpha-sialidase activity protein binding metabolic process membrane hydrolase activity, acting on glycosyl bonds organelle inner membrane lysosomal lumen	Other glycan degradation Sphingolipid metabolism
223047_at	0.348	5.386	2.539	2.252e-02	0.233	-3.459	CMTM6	CKLF-like MARVEL transmembrane domain containing 6	3	-32497807	AF116694	54918	3p22.3	Hs.380627 Hs.440494	4	cytokine activity extracellular space chemotaxis membrane integral to membrane
205514_at	0.690	4.998	2.539	2.252e-02	0.233	-3.460	ZNF415	zinc finger protein 415	19	-58303165, -58302943	NM_018355	55786	19q13.42	Hs.147765	6	DNA binding intracellular nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding
205781_at	0.248	6.378	2.538	2.253e-02	0.233	-3.460	C16orf7	chromosome 16 open reading frame 7	16	-88301041	NM_004913	9605	16q24	Hs.164410	3	transporter activity ATP synthesis coupled proton transport
209267_s_at	0.516	3.885	2.538	2.254e-02	0.233	-3.460	SLC39A8	solute carrier family 39 (zinc transporter), member 8	4	-103401843, -103401843, -103401843, -103391220	AB040120	64116	4q22-q24	Hs.288034	9	ion transport zinc ion transport zinc ion binding membrane integral to membrane metal ion transport metal ion transmembrane transporter activity
1565603_at	0.198	6.093	2.538	2.255e-02	0.233	-3.461	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	21	44351635	BE218871	5822	21q22.3	Hs.449076	11	serine-type endopeptidase activity signal transducer activity nucleus nucleolus proteolysis signal transduction
206267_s_at	0.231	6.221	2.538	2.257e-02	0.233	-3.461	MATK	megakaryocyte-associated tyrosine kinase	19	-3728966, -3728966	NM_002378	4145	19p13.3	Hs.631845	36	nucleotide binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation signal transduction mesoderm development positive regulation of cell proliferation transferase activity
203457_at	-0.267	5.895	-2.538	2.257e-02	0.233	-3.462	STX7	syntaxin 7	6	-132820355	NM_003569	8417	6q23.1	Hs.593148 Hs.605992	31	SNAP receptor activity endosome Golgi apparatus intracellular protein transport post-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
212818_s_at	0.244	7.377	2.537	2.258e-02	0.233	-3.462	ASB1	ankyrin repeat and SOCS box-containing 1	2	239000364	AF055024	51665	2q37	Hs.516788	9	molecular_function intracellular intracellular signaling cascade multicellular organismal development modification-dependent protein catabolic process negative regulation of cytokine biosynthetic process
201493_s_at	-0.463	6.999	-2.537	2.259e-02	0.233	-3.462	PUM2	pumilio homolog 2 (Drosophila)	2	-20311933	BE778078	23369	2p22-p21	Hs.467824	18	RNA binding protein binding cytoplasm regulation of translation
1557362_at	-0.233	5.273	-2.537	2.260e-02	0.233	-3.463	PHIP	pleckstrin homology domain interacting protein	6	-79700855	AI969112	55023	6q14	Hs.511817 Hs.606356	7	insulin receptor binding protein binding cellular_component insulin receptor signaling pathway
1562153_a_at	-0.265	4.461	-2.537	2.260e-02	0.233	-3.463	PVT1	Pvt1 oncogene (non-protein coding)	8	128875960	BM821521	5820	8q24	Hs.133107 Hs.675281	12
224642_at	-0.695	7.117	-2.537	2.260e-02	0.233	-3.463	FYTTD1	forty-two-three domain containing 1	3	198960820, 198961020, 198961657	BG291550	84248	3q29	Hs.277533	6
211874_s_at	-0.240	5.368	-2.537	2.261e-02	0.233	-3.463	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4	10	76256384	AF119230	23522	10q22.2	Hs.35758 Hs.599543	15	histone acetyltransferase complex nucleosome DNA binding H3/H4 histone acetyltransferase activity nucleus nucleosome assembly regulation of transcription, DNA-dependent transcription factor binding zinc ion binding acetyltransferase activity negative regulation of transcription transcription activator activity transcription repressor activity chromatin modification transferase activity histone H3 acetylation positive regulation of transcription metal ion binding
214034_at	-0.466	4.271	-2.537	2.261e-02	0.233	-3.463	ERAP1	endoplasmic reticulum aminopeptidase 1	5	-96135943, -96122269	AB011097	51752	5q15	Hs.716426	40	aminopeptidase activity interleukin-6 receptor binding interleukin-1, Type II receptor binding protein binding extracellular region cytoplasm endoplasmic reticulum endoplasmic reticulum lumen cytosol proteolysis membrane protein ectodomain proteolysis immune response regulation of blood pressure peptidase activity metalloexopeptidase activity zinc ion binding response to bacterium membrane integral to membrane antigen processing and presentation of endogenous peptide antigen via MHC class I regulation of innate immune response fat cell differentiation positive regulation of angiogenesis metal ion binding
217398_x_at	-0.185	13.779	-2.537	2.262e-02	0.233	-3.463	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	AK026525	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
224573_at	0.250	10.494	2.537	2.262e-02	0.233	-3.463	RNASEK	ribonuclease, RNase K	17	6856521	BE744389	440400	17p13.1	Hs.632232	3	endoribonuclease activity cellular_component rRNA transcription membrane integral to membrane hydrolase activity
220335_x_at	-0.381	7.966	-2.536	2.263e-02	0.233	-3.464	CES3	carboxylesterase 3	16	65552638	NM_024922	23491	16q22.1	Hs.268700	9	carboxylesterase activity endoplasmic reticulum endoplasmic reticulum lumen hydrolase activity
212462_at	-0.444	8.110	-2.536	2.263e-02	0.233	-3.464	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4	10	76256384	AU144267	23522	10q22.2	Hs.35758 Hs.599543	15	histone acetyltransferase complex nucleosome DNA binding H3/H4 histone acetyltransferase activity nucleus nucleosome assembly regulation of transcription, DNA-dependent transcription factor binding zinc ion binding acetyltransferase activity negative regulation of transcription transcription activator activity transcription repressor activity chromatin modification transferase activity histone H3 acetylation positive regulation of transcription metal ion binding
203197_s_at	0.324	8.562	2.536	2.263e-02	0.233	-3.464	C1orf123	chromosome 1 open reading frame 123	1	-53452359	AW157077	54987	1p32.3	Hs.525391	4	molecular_function cellular_component biological_process
225159_s_at	-0.434	7.796	-2.536	2.264e-02	0.233	-3.464	MED28	mediator complex subunit 28	4	17225370	AW614072	80306	4p16	Hs.434075 Hs.644788	14	actin binding protein binding nucleus cytoplasm membrane regulation of transcription
202655_at	0.372	6.927	2.536	2.264e-02	0.233	-3.464	MANF	mesencephalic astrocyte-derived neurotrophic factor	3	51397742	NM_006010	7873	3p21.1	Hs.436446	12	molecular_function extracellular region growth factor activity biological_process
228604_at	-0.474	5.460	-2.536	2.265e-02	0.233	-3.465	FAM76A	family with sequence similarity 76, member A	1	27925076	AI805069	199870	1p35.3	Hs.469359	4
208625_s_at	-0.311	8.464	-2.536	2.265e-02	0.233	-3.465	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	3	185515049, 185515664, 185520956	AF104913	1981	3q27-qter	Hs.433750	91	RNA binding translation initiation factor activity protein binding cytoplasm cytosol regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms
224565_at	-0.512	10.792	-2.535	2.267e-02	0.233	-3.465	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	BE675516	283131	11q13.1	Hs.523789 Hs.648467	6
239012_at	-0.676	7.441	-2.535	2.267e-02	0.233	-3.465	RNF144B	ring finger protein 144B	6	18495572	R83905	255488	6p22.3	Hs.148741	6	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding
243818_at	0.226	4.130	2.535	2.268e-02	0.233	-3.466	SFTA1P	surfactant associated 1 (pseudogene)	10	-10866407	T96555	207107	10p14	Hs.31562
217930_s_at	0.278	7.280	2.535	2.268e-02	0.233	-3.466	TOLLIP	toll interacting protein	11	-1252176	NM_019009	54472	11p15.5	Hs.368527	24	signal transducer activity Toll binding protein binding cytoplasm inflammatory response immune response intracellular signaling cascade cell-cell signaling phosphorylation interleukin-18 receptor complex leukocyte activation interleukin-1 receptor complex	Toll-like receptor signaling pathway
210165_at	-0.241	5.083	-2.535	2.269e-02	0.233	-3.466	DNASE1	deoxyribonuclease I	16	3642940	M55983	1773	16p13.3	Hs.629638	48	actin binding endonuclease activity deoxyribonuclease I activity deoxyribonuclease activity calcium ion binding protein binding extracellular region nucleus nuclear envelope DNA catabolic process apoptosis hydrolase activity
211890_x_at	-0.487	9.553	-2.535	2.269e-02	0.233	-3.466	CAPN3	calpain 3, (p94)	15	40427592, 40438989, 40481879, 40484268	AF127765	825	15q15.1-q21.1	Hs.143261	66	calcium-dependent cysteine-type endopeptidase activity signal transducer activity calcium ion binding intracellular cytoplasm proteolysis muscle organ development peptidase activity
236324_at	0.246	4.540	2.535	2.270e-02	0.233	-3.467	MBP	myelin basic protein	18	-72853726, -72819776, -72819776	BE676488	4155	18q23	Hs.551713	102	plasma membrane immune response synaptic transmission central nervous system development structural constituent of myelin sheath internode region of axon myelination cell projection cell soma myelin sheath
212604_at	0.291	8.286	2.535	2.270e-02	0.233	-3.467	MRPS31	mitochondrial ribosomal protein S31	13	-40201431	AI937794	10240	13q14.11	Hs.154655	8	mitochondrion ribosome protein domain specific binding
200925_at	0.414	8.048	2.535	2.270e-02	0.233	-3.467	COX6A1	cytochrome c oxidase subunit VIa polypeptide 1	12	119360286	NM_004373	1337	12q24.2	Hs.497118	11	cytochrome-c oxidase activity mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex IV generation of precursor metabolites and energy membrane	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
206387_at	0.282	4.762	2.535	2.270e-02	0.233	-3.467	CDX2	caudal type homeobox 2	13	-27434277	U51096	1045	13q12.3	Hs.174249	103	negative regulation of transcription from RNA polymerase II promoter condensed nuclear chromosome blood vessel development blastocyst development trophectodermal cell differentiation placenta development transcription factor activity transcription corepressor activity protein binding nucleus regulation of transcription, DNA-dependent pattern specification process organ morphogenesis transcriptional repressor complex somatic stem cell maintenance sequence-specific DNA binding positive regulation of cell differentiation
214242_at	0.215	4.748	2.535	2.270e-02	0.233	-3.467	MAN1A2	mannosidase, alpha, class 1A, member 2	1	117711607	AI189305	10905	1p13	Hs.435938	25	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding membrane fraction Golgi apparatus N-glycan processing metabolic process membrane integral to membrane hydrolase activity, acting on glycosyl bonds	N-Glycan biosynthesis Metabolic pathways
202311_s_at	0.630	3.907	2.534	2.272e-02	0.233	-3.468	COL1A1	collagen, type I, alpha 1	17	-45616455	AI743621	1277	17q21.33	Hs.172928 Hs.681002	360	ossification blood vessel development extracellular matrix structural constituent extracellular region extracellular region collagen collagen type I plasma membrane response to nutrient visual perception sensory perception of sound response to mechanical stimulus response to inorganic substance collagen fibril organization response to corticosteroid stimulus collagen biosynthetic process tooth mineralization response to hydrogen peroxide identical protein binding response to peptide hormone stimulus skin morphogenesis platelet-derived growth factor binding embryonic skeletal system development response to cAMP	Focal adhesion ECM-receptor interaction
208463_at	0.293	4.592	2.534	2.274e-02	0.233	-3.468	GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	4	-46615673	NM_000809	2557	4p12	Hs.248112	17	GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport chloride transport gamma-aminobutyric acid signaling pathway benzodiazepine receptor activity cell junction chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
226533_at	-0.426	6.519	-2.533	2.277e-02	0.234	-3.470	HINT3	histidine triad nucleotide binding protein 3	6	126319553	BF694956	135114	6q22.32	Hs.72325	6	nucleus cytoplasm hydrolase activity
225260_s_at	0.220	9.244	2.533	2.277e-02	0.234	-3.470	MRPL32	mitochondrial ribosomal protein L32	7	42938463	AL551823	64983	7p14	Hs.50252	11	structural constituent of ribosome mitochondrion mitochondrial inner membrane mitochondrial ribosome ribosome translation translation regulator activity
230992_at	0.473	5.744	2.533	2.278e-02	0.234	-3.470	BTNL9	butyrophilin-like 9	5	180399830	T47960	153579	5q35.3	Hs.546502	4	membrane integral to membrane
218343_s_at	-0.365	6.702	-2.533	2.278e-02	0.234	-3.470	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	2	-197337344	NM_012086	9330	2q33.1	Hs.470996	10	transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity binding nucleus transcription, DNA-dependent 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter
200902_at	-0.307	8.296	-2.533	2.279e-02	0.234	-3.470	SEP15	15 kDa selenoprotein	1	-87100715	NM_004261	9403	1p31	Hs.362728	16	protein binding endoplasmic reticulum endoplasmic reticulum lumen selenium binding 'de novo' posttranslational protein folding
205978_at	0.289	3.368	2.532	2.280e-02	0.234	-3.471	KL	klotho	13	32488570	NM_004795	9365	13q12	Hs.524953	62	beta-glucuronidase activity signal transducer activity hormone activity vitamin D binding protein binding extracellular region extracellular region extracellular space membrane fraction soluble fraction plasma membrane plasma membrane integral to plasma membrane carbohydrate metabolic process energy reserve metabolic process aging metabolic process beta-glucosidase activity fibroblast growth factor receptor signaling pathway positive regulation of bone mineralization cation binding
218705_s_at	-0.365	6.635	-2.532	2.281e-02	0.234	-3.471	SNX24	sorting nexin 24	5	122209058	NM_014035	28966	5q23.2	Hs.483200	5	protein binding cell communication protein transport phosphoinositide binding
228224_at	0.257	5.690	2.532	2.283e-02	0.234	-3.472	PRELP	proline/arginine-rich end leucine-rich repeat protein	1	201711505	AA573140	5549	1q32	Hs.632481	13	skeletal system development extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix cell aging
234257_at	0.291	4.401	2.532	2.284e-02	0.234	-3.472	TNS3	tensin 3	7	-47281276	AL137468	64759	7p12.3	Hs.520814	12	protein binding nucleus nucleolus cytoplasm plasma membrane focal adhesion positive regulation of cell proliferation cell migration cell junction lung alveolus development
230200_at	0.273	6.540	2.532	2.284e-02	0.234	-3.472	NSUN6	NOL1/NOP2/Sun domain family, member 6	10	-18874269	BF433689	221078	10p12.31	Hs.396175	4	RNA binding methyltransferase activity transferase activity
203726_s_at	0.341	4.918	2.531	2.285e-02	0.234	-3.473	LAMA3	laminin, alpha 3	18	19523559, 19706981	NM_000227	3909	18q11.2	Hs.436367	49	receptor binding structural molecule activity extracellular region basement membrane laminin-1 complex epidermis development regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
208563_x_at	0.256	4.175	2.531	2.287e-02	0.234	-3.473	POU3F3	POU class 3 homeobox 3	2	104838400	NM_006236	5455	2q12.1	Hs.673855	6	kidney development transcription factor activity nucleus regulation of transcription, DNA-dependent central nervous system development cerebral cortex radially oriented cell migration forebrain ventricular zone progenitor cell division sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter
224484_s_at	-0.412	4.733	-2.530	2.289e-02	0.234	-3.474	BRMS1L	breast cancer metastasis-suppressor 1-like	14	35365347	BC006250	84312	14q13.2	Hs.525299	3	nucleus regulation of growth regulation of transcription
223424_s_at	-0.277	6.552	-2.530	2.290e-02	0.234	-3.475	ZSCAN21	zinc finger and SCAN domain containing 21	7	99485352	AL136865	7589	7q22.1	Hs.632294	9	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription activator activity metal ion binding
218177_at	-0.410	5.945	-2.529	2.295e-02	0.235	-3.476	CHMP1B	chromatin modifying protein 1B	18	11841388	AA293502	57132	18p11.21	Hs.656244	16	cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division	Endocytosis
230266_at	0.447	5.235	2.529	2.295e-02	0.235	-3.477	RAB7B	RAB7B, member RAS oncogene family	1		AI127991	338382	1q32	Hs.534612	4	nucleotide binding GTP binding lysosome small GTPase mediated signal transduction protein transport
220579_at	-0.257	4.036	-2.529	2.295e-02	0.235	-3.477	FLJ14100	hypothetical protein FLJ14100	1		NM_025025	80093	1p36.33	Hs.711221	1
1561232_at	0.194	2.953	2.529	2.297e-02	0.235	-3.477	LOC100270680	hypothetical LOC100270680	8		BC042052	100270680	8q24	Hs.333720	1
207962_at	0.252	4.376	2.528	2.299e-02	0.235	-3.478	CAPN11	calpain 11	6	44234525	NM_007058	11131	6p12	Hs.225953	8	acrosomal vesicle calcium-dependent cysteine-type endopeptidase activity calcium ion binding intracellular proteolysis peptidase activity
218178_s_at	-0.428	8.778	-2.528	2.299e-02	0.235	-3.478	CHMP1B	chromatin modifying protein 1B	18	11841388	NM_020412	57132	18p11.21	Hs.656244	16	cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division	Endocytosis
228697_at	-0.390	9.162	-2.528	2.300e-02	0.235	-3.478	HINT3	histidine triad nucleotide binding protein 3	6	126319553	AW731710	135114	6q22.32	Hs.72325	6	nucleus cytoplasm hydrolase activity
53720_at	0.299	6.198	2.528	2.300e-02	0.235	-3.478	C19orf66	chromosome 19 open reading frame 66	19	10057805	AI862559	55337	19p13.2	Hs.655613	2
230529_at	0.236	4.471	2.527	2.303e-02	0.235	-3.480	HECA	headcase homolog (Drosophila)	6	139497941	BE676408	51696	6q23-q24	Hs.197644	6	molecular_function cellular_component multicellular organismal development respiratory tube development
235551_at	-0.223	3.803	-2.527	2.304e-02	0.235	-3.480	WDR4	WD repeat domain 4	21	-43142404, -43136272	AA555280	10785	21q22.3	Hs.248815	10	protein binding nucleus nucleoplasm cytoplasm tRNA modification tRNA (guanine-N7-)-methyltransferase activity
202169_s_at	-0.345	9.072	-2.527	2.304e-02	0.235	-3.480	AASDHPPT	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	11	105453501	AF302110	60496	11q22	Hs.524009	9	magnesium ion binding protein binding cytoplasm cytosol holo-[acyl-carrier-protein] synthase activity holo-[acyl-carrier-protein] synthase activity macromolecule biosynthetic process transferase activity	Lysine biosynthesis Lysine degradation Metabolic pathways
209602_s_at	0.452	2.718	2.527	2.304e-02	0.235	-3.480	GATA3	GATA binding protein 3	10	8136672	AI796169	2625	10p15	Hs.524134	92	transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter defense response transcription factor binding zinc ion binding anatomical structure morphogenesis sequence-specific DNA binding response to estrogen stimulus metal ion binding
229310_at	-0.633	5.992	-2.527	2.305e-02	0.235	-3.480	KLHL29	kelch-like 29 (Drosophila)	2		BE465475	114818	2p24.1	Hs.130593	5	protein binding
200989_at	0.360	7.856	2.527	2.305e-02	0.235	-3.480	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	61231871	NM_001530	3091	14q21-q24	Hs.597216	743	response to hypoxia neural crest cell migration epithelial to mesenchymal transition embryonic placenta development positive regulation of endothelial cell proliferation heart looping connective tissue replacement during inflammatory response RNA polymerase II transcription factor activity, enhancer binding signal transducer activity nucleus transcription factor complex nucleolus cytoplasm lactate metabolic process regulation of transcription, DNA-dependent cellular iron ion homeostasis signal transduction transcription factor binding microtubule-based flagellum positive regulation vascular endothelial growth factor production positive regulation of epithelial cell migration response to muscle activity cell differentiation positive regulation of vascular endothelial growth factor receptor signaling pathway oxygen homeostasis positive regulation of chemokine production regulation of transforming growth factor-beta2 production collagen metabolic process histone acetyltransferase binding embryonic hemopoiesis hemoglobin biosynthetic process glucose homeostasis mRNA transcription from RNA polymerase II promoter regulation of apoptosis positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of angiogenesis positive regulation of glycolysis negative regulation of growth positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter muscle maintenance positive regulation of hormone biosynthetic process protein heterodimerization activity protein heterodimerization activity regulation of catalytic activity positive regulation of nitric-oxide synthase activity cartilage development elastin metabolic process Hsp90 protein binding	mTOR signaling pathway Pathways in cancer Renal cell carcinoma
211813_x_at	0.537	10.438	2.527	2.306e-02	0.235	-3.481	DCN	decorin	12	-90063165, -90063165, -90063165	AF138303	1634	12q21.33	Hs.718429	104	protein binding glycosaminoglycan binding extracellular region proteinaceous extracellular matrix organ morphogenesis peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix binding	TGF-beta signaling pathway
227357_at	-0.350	7.546	-2.526	2.308e-02	0.235	-3.482	MAP3K7IP3	mitogen-activated protein kinase kinase kinase 7 interacting protein 3	X	-30755479	BF593914	257397	Xp21.2	Hs.188256	10	protein binding intracellular zinc ion binding metal ion binding
238648_at	0.233	4.713	2.526	2.310e-02	0.235	-3.482	FLJ42291	hypothetical LOC346547	7		BE671597	346547	7q36.2
218539_at	-0.347	8.323	-2.526	2.311e-02	0.235	-3.483	FBXO34	F-box protein 34	14	54807773, 54808624	NM_017943	55030	14q22.3	Hs.525348 Hs.654725	9	protein transport modification-dependent protein catabolic process
201487_at	-0.745	6.643	-2.526	2.311e-02	0.235	-3.483	CTSC	cathepsin C	11	-87693628, -87666407	NM_001814	1075	11q14.1-q14.3	Hs.128065 Hs.706874	51	cysteine-type endopeptidase activity lysosome proteolysis immune response peptidase activity chloride ion binding	Lysosome
210587_at	1.249	4.259	2.526	2.312e-02	0.235	-3.483	INHBE	inhibin, beta E	12	56135362	BC005161	83729	12q13.3	Hs.632713	7	hormone activity extracellular region growth factor activity	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
217884_at	-0.241	6.230	-2.525	2.312e-02	0.235	-3.483	NAT10	N-acetyltransferase 10 (GCN5-related)	11	34083686	NM_024662	55226	11p13	Hs.577281	18	nucleotide binding molecular_function protein binding ATP binding nucleus nucleolus N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
238912_x_at	-0.332	7.568	-2.525	2.312e-02	0.235	-3.483	C9orf85	chromosome 9 open reading frame 85	9	73716242	AA824363	138241	9q21.13	Hs.534190	4
242513_x_at	-0.249	2.212	-2.525	2.313e-02	0.235	-3.483	KIAA2018	KIAA2018	3	-114849922	R49243	205717	3q13.2	Hs.632570	1	DNA binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding nucleus membrane transcription regulator activity regulation of transcription
222513_s_at	-0.509	9.170	-2.525	2.313e-02	0.235	-3.483	SORBS1	sorbin and SH3 domain containing 1	10	-97061519, -97061519	N21458	10580	10q23.3-q24.1	Hs.719081	35	stress fiber actin binding SH3/SH2 adaptor activity SH3/SH2 adaptor activity insulin receptor binding nucleus cytoplasm cytosol cytoskeleton plasma membrane insulin receptor complex zonula adherens cell-substrate adherens junction transport insulin receptor signaling pathway glucose transport cell junction stress fiber formation membrane raft positive regulation of glycogen biosynthetic process positive regulation of glucose import positive regulation of lipid biosynthetic process focal adhesion formation	PPAR signaling pathway Adherens junction Insulin signaling pathway
225498_at	-0.343	10.146	-2.525	2.313e-02	0.235	-3.484	CHMP4B	chromatin modifying protein 4B	20	31862779	AV713673	128866	20q11.22	Hs.472471	19	cytoplasm endosome cytosol protein transport membrane	Endocytosis
221641_s_at	-0.358	7.343	-2.525	2.314e-02	0.235	-3.484	ACOT9	acyl-CoA thioesterase 9	X	-23631697	AF241787	23597	Xp22.11	Hs.298885	6	acetyl-CoA hydrolase activity carboxylesterase activity mitochondrion acyl-CoA metabolic process hydrolase activity
209985_s_at	0.276	5.694	2.525	2.314e-02	0.235	-3.484	ASCL1	achaete-scute complex homolog 1 (Drosophila)	12	101875581	BE797438	429	12q23.2	Hs.704281	40	neuron migration transcription factor activity protein binding nucleus pattern specification process nervous system development neuroblast fate determination neuroblast proliferation oligodendrocyte development spinal cord association neuron differentiation spinal cord oligodendrocyte cell fate specification oligodendrocyte cell fate commitment central nervous system neuron development cerebral cortex development cell soma sequence-specific DNA binding regulation of transcription positive regulation of Notch signaling pathway positive regulation of transcription from RNA polymerase II promoter subpallium neuron fate commitment regulation of timing of subpallium neuron differentiation olfactory pit development
204957_at	-0.373	6.275	-2.525	2.314e-02	0.235	-3.484	ORC5L	origin recognition complex, subunit 5-like (yeast)	7	-103595859, -103554023	NM_002553	5001	7q22.1	Hs.432948	28	nucleotide binding DNA replication origin binding ATP binding nucleus nucleoplasm DNA replication DNA replication DNA replication initiation identical protein binding	Cell cycle
204868_at	0.270	8.521	2.525	2.315e-02	0.235	-3.484	ICT1	immature colon carcinoma transcript 1	17	70520374	NM_001545	3396	17q25.1	Hs.407955	6	molecular_function translation release factor activity cellular_component translational termination biological_process
210080_x_at	0.236	4.463	2.525	2.315e-02	0.235	-3.484	CELA3A	chymotrypsin-like elastase family, member 3A	1	22200735	D00306	10136	1p36.12	Hs.654349	7	serine-type endopeptidase activity proteolysis digestion cholesterol metabolic process peptidase activity
242761_s_at	0.459	6.379	2.525	2.316e-02	0.235	-3.485	ZNF420	zinc finger protein 420	19	42261221	AI061288	147923	19q13.12	Hs.444992	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222562_s_at	-0.791	5.576	-2.524	2.318e-02	0.235	-3.485	TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	10	93548130	BF060683	80351	10q23.3	Hs.329327	15	pericentriolar material nuclear chromosome, telomeric region NAD+ ADP-ribosyltransferase activity nucleus nuclear envelope chromosome cytoplasm microsome Golgi apparatus protein amino acid ADP-ribosylation membrane transferase activity, transferring glycosyl groups positive regulation of telomere maintenance via telomerase regulation of multicellular organism growth perinuclear region of cytoplasm protein localization to telomere
213644_at	-0.386	6.059	-2.524	2.318e-02	0.235	-3.486	CCDC46	coiled-coil domain containing 46	17	-61062119, -61062119	AI979276	201134	17q24.1	Hs.408676	4
244527_at	0.231	3.058	2.524	2.319e-02	0.235	-3.486	TRIO	triple functional domain (PTPRF interacting)	5	14196828	BG055304	7204	5p15.2	Hs.130031	22	nucleotide binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity ATP binding intracellular cytoplasm protein amino acid phosphorylation transmembrane receptor protein tyrosine phosphatase signaling pathway transferase activity regulation of Rho protein signal transduction
242304_at	0.242	7.681	2.524	2.319e-02	0.235	-3.486	WIBG	within bgcn homolog (Drosophila)	12	-54581463, -54581463	AI377416	84305	12q13.2	Hs.505687 Hs.711082	6	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm exon-exon junction complex ribosome binding positive regulation of translation
210995_s_at	-0.445	4.580	-2.524	2.319e-02	0.235	-3.486	TRIM23	tripartite motif-containing 23	5	-64921262	AF230399	373	5q12.3	Hs.792	14	Golgi membrane nucleotide binding GTPase activity ubiquitin-protein ligase activity protein binding GTP binding intracellular nucleus cytoplasm lysosomal membrane Golgi apparatus small GTPase mediated signal transduction enzyme activator activity zinc ion binding membrane protein ubiquitination GDP binding metal ion binding
230093_at	0.225	3.829	2.524	2.320e-02	0.235	-3.486	RSPH1	radial spoke head 1 homolog (Chlamydomonas)	21	-42765665	AI683428	89765	21q22.3	Hs.661069	7	nucleus cytoplasm cytosol meiosis
35179_at	0.202	5.215	2.524	2.320e-02	0.235	-3.486	B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	11	-62139343	AB009598	26229	11q12.3	Hs.502759	13	Golgi membrane Golgi apparatus glycosaminoglycan biosynthetic process galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity membrane integral to membrane transferase activity manganese ion binding metal ion binding	Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways
224847_at	0.284	5.832	2.524	2.320e-02	0.235	-3.486	CDK6	cyclin-dependent kinase 6	7	-92072172, -92072172	AW051349	1021	7q21-q22	Hs.119882	95	G1 phase of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex ruffle positive regulation of cell-matrix adhesion cyclin-dependent protein kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation regulation of gene expression regulation of gene expression transferase activity hemopoiesis cyclin binding gliogenesis cell dedifferentiation regulation of erythrocyte differentiation negative regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of fibroblast proliferation negative regulation of epithelial cell proliferation cell division	Cell cycle p53 signaling pathway Pathways in cancer Pancreatic cancer Glioma Melanoma Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer
1558290_a_at	0.272	5.092	2.524	2.320e-02	0.235	-3.486	PVT1	Pvt1 oncogene (non-protein coding)	8	128875960	BG200951	5820	8q24	Hs.133107 Hs.675281	12
208660_at	0.343	11.140	2.524	2.321e-02	0.235	-3.487	CS	citrate synthase	12	-54951749	BC000105	1431	12q13.2-q13.3	Hs.430606 Hs.715526	20	citrate (Si)-synthase activity citrate (Si)-synthase activity mitochondrion mitochondrial matrix mitochondrial matrix tricarboxylic acid cycle transferase activity cellular carbohydrate metabolic process	Citrate cycle (TCA cycle) Glyoxylate and dicarboxylate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
200707_at	0.277	4.896	2.523	2.323e-02	0.236	-3.487	PRKCSH	protein kinase C substrate 80K-H	19	11407268	NM_002743	5589	19p13.2	Hs.610830	32	molecular_function calcium ion binding protein binding intracellular endoplasmic reticulum protein kinase cascade
209176_at	-0.230	5.664	-2.523	2.324e-02	0.236	-3.488	SEC23IP	SEC23 interacting protein	10	121642212	AI332962	11196	10q25-q26	Hs.435004	8	protein binding cytoplasm endoplasmic reticulum ER-Golgi intermediate compartment intracellular protein transport Golgi organization membrane cytoplasmic vesicle metal ion binding
32088_at	-0.355	3.964	-2.523	2.325e-02	0.236	-3.488	BLZF1	basic leucine zipper nuclear factor 1	1	167603817	U79751	8548	1q24	Hs.130746	16	regulation of cell growth transcription factor activity nucleus cytoplasm Golgi apparatus Golgi lumen regulation of transcription from RNA polymerase II promoter cell proliferation protein transport vesicle-mediated transport
201413_at	0.314	8.526	2.522	2.326e-02	0.236	-3.489	HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	5	118816046	NM_000414	3295	5q21	Hs.406861	44	very-long-chain fatty acid metabolic process 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity estradiol 17-beta-dehydrogenase activity sterol carrier activity protein binding mitochondrion peroxisome peroxisomal matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation sterol transporter activity oxidoreductase activity lyase activity isomerase activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity oxidation reduction Sertoli cell development	Primary bile acid biosynthesis Metabolic pathways
227068_at	-0.561	7.785	-2.522	2.327e-02	0.236	-3.489	PGK1	phosphoglycerate kinase 1	X	77246321	AA069778	5230	Xq13	Hs.78771	52	nucleotide binding phosphoglycerate kinase activity ATP binding cytoplasm glycolysis phosphorylation transferase activity	Glycolysis / Gluconeogenesis Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
231876_at	0.279	6.398	2.522	2.328e-02	0.236	-3.489	TRIM56	tripartite motif-containing 56	7	100515505	AL512757	81844	7q22.1	Hs.521092	5	protein binding intracellular zinc ion binding metal ion binding
203317_at	0.264	4.215	2.522	2.329e-02	0.236	-3.490	PSD4	pleckstrin and Sec7 domain containing 4	2	113648030	NM_012455	23550	2q13	Hs.516306	8	ARF guanyl-nucleotide exchange factor activity intracellular plasma membrane regulation of ARF protein signal transduction	Endocytosis
219298_at	0.441	8.296	2.522	2.330e-02	0.236	-3.490	ECHDC3	enoyl Coenzyme A hydratase domain containing 3	10	11824361	NM_024693	79746	10p14	Hs.22242	4	catalytic activity mitochondrion metabolic process
1556262_at	-0.250	5.895	-2.521	2.331e-02	0.236	-3.490	PWRN1	Prader-Willi region non-protein coding RNA 1	15	22354396	AK058147	791114	15q11.2	Hs.456065	2
202966_at	0.354	3.606	2.521	2.331e-02	0.236	-3.490	CAPN6	calpain 6	X	-110374986	NM_014289	827	Xq23	Hs.496593	8	calcium-dependent cysteine-type endopeptidase activity intracellular proteolysis
202833_s_at	0.229	2.718	2.521	2.331e-02	0.236	-3.491	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	14	-93912836, -93912836	NM_000295	5265	14q32.1	Hs.525557	265	protease binding serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular region proteinaceous extracellular matrix extracellular space acute-phase response blood coagulation peptidase activity peptidase inhibitor activity platelet alpha granule lumen	Complement and coagulation cascades
229876_at	-0.915	8.989	-2.521	2.332e-02	0.236	-3.491	PHKA1	phosphorylase kinase, alpha 1 (muscle)	X	-71715388	BE503584	5255	Xq12-q13	Hs.201379	12	catalytic activity phosphorylase kinase activity calmodulin binding cytoplasm plasma membrane carbohydrate metabolic process glycogen metabolic process generation of precursor metabolites and energy intracellular membrane-bounded organelle	Calcium signaling pathway Insulin signaling pathway
239297_at	0.240	4.095	2.521	2.334e-02	0.236	-3.492	C8orf79	chromosome 8 open reading frame 79	8	12847553, 12914143	BE932011	57604	8p22	Hs.202521	5	metabolic process methyltransferase activity transferase activity
225677_at	-0.324	7.799	-2.521	2.334e-02	0.236	-3.492	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	AW152589	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
201995_at	0.223	5.595	2.520	2.336e-02	0.236	-3.492	EXT1	exostoses (multiple) 1	8	-118880782	NM_000127	2131	8q24.11-q24.13	Hs.492618	53	Golgi membrane skeletal system development ossification protein binding endoplasmic reticulum Golgi apparatus glycosaminoglycan biosynthetic process signal transduction gastrulation endoderm development mesoderm development heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process membrane integral to membrane integral to endoplasmic reticulum membrane heparan sulfate N-acetylglucosaminyltransferase activity protein homodimerization activity protein heterodimerization activity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	Heparan sulfate biosynthesis Metabolic pathways
238402_s_at	0.265	6.487	2.520	2.339e-02	0.236	-3.494	FLJ35220	hypothetical protein FLJ35220	17	76003561	AI311040	284131	17q25.3	Hs.389678	2	endonuclease activity DNA repair response to DNA damage stimulus hydrolase activity
212333_at	-0.319	8.992	-2.519	2.342e-02	0.237	-3.495	FAM98A	family with sequence similarity 98, member A	2	-33662232	AL049943	25940	2p22.3	Hs.468140	2
232812_at	0.239	3.841	2.519	2.343e-02	0.237	-3.495	LOC401052	hypothetical LOC401052	3	-10023101	AK022260	401052	3p25.3	Hs.662766	1
204200_s_at	0.312	5.973	2.519	2.344e-02	0.237	-3.496	PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	22	-37949632, -37949632	NM_002608	5155	22q12.3-q13.1 22q13.1	Hs.1976	140	response to hypoxia positive regulation of endothelial cell proliferation monocyte chemotaxis platelet-derived growth factor receptor binding collagen binding extracellular region extracellular region cytoplasm substrate-bound cell migration transforming growth factor beta receptor signaling pathway growth factor activity response to wounding cell surface negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation positive regulation of smooth muscle cell migration membrane cell growth cell projection assembly actin cytoskeleton organization negative regulation of cell migration platelet dense granule lumen protein homodimerization activity positive regulation of MAP kinase activity cell surface binding positive regulation of blood vessel endothelial cell migration positive regulation of DNA replication protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding regulation of peptidyl-tyrosine phosphorylation positive regulation of chemotaxis cell chemotaxis	MAPK signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Renal cell carcinoma Glioma Prostate cancer Melanoma
1564029_at	-0.218	2.763	-2.518	2.345e-02	0.237	-3.496	USP49	ubiquitin specific peptidase 49	6	-41873360	AL049937	25862	6p21	Hs.665742	5	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding
212237_at	-0.356	6.826	-2.518	2.346e-02	0.237	-3.496	ASXL1	additional sex combs like 1 (Drosophila)	20	30409813	N64780	171023	20q11.1	Hs.374043	13	protein binding nucleus zinc ion binding regulation of transcription metal ion binding
1557455_s_at	-0.472	5.701	-2.518	2.347e-02	0.237	-3.497	MOSPD1	motile sperm domain containing 1	X	-133849327	AF086333	56180	Xq26.3	Hs.590789	4	structural molecule activity membrane integral to membrane
226732_at	-0.466	6.980	-2.517	2.349e-02	0.237	-3.497	RBM33	RNA binding motif protein 33	7	155129963	AI823400	155435	7q36.3	Hs.591815	10	RNA binding
219995_s_at	0.634	2.261	2.517	2.350e-02	0.237	-3.498	ZNF750	zinc finger protein 750	17	-78380598	NM_024702	79755	17q25.3	Hs.464391 Hs.653124	6	intracellular zinc ion binding
227192_at	0.233	4.884	2.517	2.351e-02	0.237	-3.498	PRRT2	proline-rich transmembrane protein 2	16	29730909	BF060707	112476	16p11.2	Hs.655071	5	response to biotic stimulus membrane integral to membrane
211926_s_at	0.430	7.188	2.517	2.352e-02	0.237	-3.498	MYH9	myosin, heavy chain 9, non-muscle	22	-35007269	AI827941	4627	22q13.1	Hs.474751	112	microfilament motor activity nucleotide binding meiotic spindle organization cell morphogenesis involved in differentiation cytokinesis angiogenesis in utero embryonic development stress fiber ruffle establishment of T cell polarity immunological synapse uropod calmodulin binding ATP binding nucleus cytoplasm spindle contractile ring cytosol plasma membrane cell-cell adherens junction cell cortex membrane protein ectodomain proteolysis cell motion meiotic metaphase I integrin-mediated signaling pathway myoblast fusion integrin complex regulation of cell shape protein transport cell-cell adhesion myosin complex ATPase activity actin filament-based movement platelet formation monocyte differentiation cortical cytoskeleton actin-dependent ATPase activity actin cytoskeleton reorganization neuromuscular junction cleavage furrow uropod organization protein homodimerization activity protein anchor ADP binding blood vessel endothelial cell migration leukocyte migration actin filament binding actin filament binding establishment of meiotic spindle localization	Tight junction Regulation of actin cytoskeleton
209475_at	-0.461	8.447	-2.517	2.352e-02	0.237	-3.498	USP15	ubiquitin specific peptidase 15	12	60940453	AF106069	9958	12q14	Hs.434951	14	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding ubiquitin-dependent protein catabolic process peptidase activity
226527_at	-0.284	6.621	-2.517	2.352e-02	0.237	-3.499	RPRD2	regulation of nuclear pre-mRNA domain containing 2	1	148603613	AI569785	23248	1q21.3	Hs.213666	9	protein binding
235324_at	-0.229	3.770	-2.516	2.357e-02	0.237	-3.500	SFRS3	splicing factor, arginine/serine-rich 3	6	36670067	AI445255	6428	6p21	Hs.405144	34	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus RNA splicing
217863_at	-0.385	6.856	-2.515	2.360e-02	0.237	-3.502	PIAS1	protein inhibitor of activated STAT, 1	15	66133625	AI348378	8554	15q	Hs.162458	67	DNA binding transcription coactivator activity transcription corepressor activity nucleus JAK-STAT cascade zinc ion binding nuclear speck SUMO ligase activity enzyme binding modification-dependent protein catabolic process androgen receptor signaling pathway positive regulation of protein sumoylation regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding	Ubiquitin mediated proteolysis Jak-STAT signaling pathway Pathways in cancer Small cell lung cancer
221203_s_at	0.305	5.690	2.515	2.360e-02	0.237	-3.502	YEATS2	YEATS domain containing 2	3	184898299	NM_018023	55689	3q27.1	Hs.632575	5	nucleus regulation of transcription, DNA-dependent
211368_s_at	0.497	4.141	2.514	2.367e-02	0.238	-3.504	CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	11	-104401446	U13700	834	11q23	Hs.2490	134	cysteine-type endopeptidase activity protein binding intracellular cytoplasm proteolysis signal transduction peptidase activity caspase activator activity regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade	Amyotrophic lateral sclerosis (ALS)
236847_at	0.429	5.663	2.514	2.367e-02	0.238	-3.504	C19orf18	chromosome 19 open reading frame 18	19	-63161616	AI650509	147685	19q13.43	Hs.134209	2	membrane integral to membrane
226864_at	-0.337	11.198	-2.514	2.367e-02	0.238	-3.504	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	8	79590890	BF245954	5569	8q21.12	Hs.433700	15	negative regulation of transcription from RNA polymerase II promoter protein kinase inhibitor activity cAMP-dependent protein kinase inhibitor activity soluble fraction nucleus cytoplasm negative regulation of protein kinase activity regulation of G2/M transition of mitotic cell cycle negative regulation of protein import into nucleus negative regulation of catalytic activity
228829_at	-0.484	6.651	-2.513	2.369e-02	0.238	-3.505	ATF7	activating transcription factor 7	12	-52192109, -52192109	AI279868	11016	12q13	Hs.12286	18	transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding protein dimerization activity
229477_at	0.627	5.507	2.513	2.372e-02	0.238	-3.506	THRSP	thyroid hormone responsive (SPOT14 homolog, rat)	11	77452554	AW272342	7069	11q13.5	Hs.591969	12	protein binding nucleus lipid metabolic process
219319_at	0.221	5.926	2.512	2.374e-02	0.238	-3.507	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	NM_022462	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
214434_at	0.280	5.592	2.512	2.375e-02	0.238	-3.507	HSPA12A	heat shock 70kDa protein 12A	10	-118420692	AB007877	259217	10q26.12	Hs.654682	8	nucleotide binding ATP binding
235120_at	-0.214	4.780	-2.512	2.376e-02	0.238	-3.508	SEC22C	SEC22 vesicle trafficking protein homolog C (S. cerevisiae)	3	-42569395, -42564476	W52819	9117	3p22.1	Hs.445892	4	endoplasmic reticulum ER to Golgi vesicle-mediated transport protein transport membrane integral to membrane vesicle-mediated transport
233517_s_at	0.242	5.630	2.512	2.377e-02	0.238	-3.508	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	AK021421	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
1569320_at	-0.393	5.394	-2.512	2.377e-02	0.238	-3.508	GPBP1L1	GC-rich promoter binding protein 1-like 1	1	-45865564	CA391618	60313	1p34.1	Hs.238432	4	DNA binding nucleus regulation of transcription
202241_at	-0.767	8.827	-2.511	2.378e-02	0.239	-3.509	TRIB1	tribbles homolog 1 (Drosophila)	8	126511744	NM_025195	10221	8q24.13	Hs.444947	19	protein kinase activity protein kinase inhibitor activity ATP binding nucleus cytoplasm protein amino acid phosphorylation negative regulation of protein kinase activity JNK cascade transcription factor binding negative regulation of smooth muscle cell migration mitogen-activated protein kinase kinase binding negative regulation of lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide regulation of MAP kinase activity negative regulation of transcription factor activity negative regulation of smooth muscle cell proliferation
1553366_s_at	-0.608	8.703	-2.511	2.380e-02	0.239	-3.509	ANKRD23	ankyrin repeat domain 23	2	-96867377	NM_144994	200539	2q11.2	Hs.643430	8	nucleus
226069_at	0.525	5.238	2.511	2.380e-02	0.239	-3.509	PRICKLE1	prickle homolog 1 (Drosophila)	12	-41138407, -41138407, -41138407	AA404269	144165	12q12	Hs.524348 Hs.639400	14	nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding	Wnt signaling pathway
202776_at	-0.303	7.875	-2.511	2.381e-02	0.239	-3.509	DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	1	-94107923	NM_014597	30836	1p22.1	Hs.85769	10	nucleus regulation of transcription
240037_at	0.277	4.505	2.510	2.382e-02	0.239	-3.510	ITPRIPL1	inositol 1,4,5-triphosphate receptor interacting protein-like 1	2	96354788, 96354795, 96355661, 96355671	R37132	150771	2q11.2	Hs.65009	3	membrane integral to membrane
219229_at	0.361	5.525	2.510	2.383e-02	0.239	-3.510	SLCO3A1	solute carrier organic anion transporter family, member 3A1	15	90197941, 90197941	NM_013272	28232	15q26	Hs.311187	10	transporter activity ion transport membrane integral to membrane
223356_s_at	0.227	8.428	2.510	2.384e-02	0.239	-3.511	MTIF3	mitochondrial translational initiation factor 3	13	-26907780	BG529919	219402	13q12.2	Hs.534582	6	translation initiation factor activity mitochondrion regulation of translational initiation ribosome disassembly ribosomal small subunit binding
1568924_a_at	-0.422	4.037	-2.510	2.384e-02	0.239	-3.511	IQUB	IQ motif and ubiquitin domain containing	7	-122879473	BC026173	154865	7q31.32	Hs.159650 Hs.719777	5
227448_at	-0.579	6.543	-2.510	2.384e-02	0.239	-3.511	ARGLU1	arginine and glutamate rich 1	13	-105993662	AL045916	55082	13q33.3	Hs.508644 Hs.701016	3
226650_at	0.388	6.071	2.510	2.384e-02	0.239	-3.511	ZFAND2A	zinc finger, AN1-type domain 2A	7	-1159069	AI984061	90637	7p22.3	Hs.648111	2	nucleus cytoplasm zinc ion binding metal ion binding
218353_at	0.528	9.716	2.510	2.385e-02	0.239	-3.511	RGS5	regulator of G-protein signaling 5	1	-161378720	NM_025226	8490	1q23.1	Hs.24950	26	signal transducer activity GTPase activator activity regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction
205390_s_at	0.488	8.264	2.510	2.385e-02	0.239	-3.511	ANK1	ankyrin 1, erythrocytic	8	-41629901, -41629901, -41629900	NM_000037	286	8p11.1	Hs.654438 Hs.667377	49	structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity
202411_at	0.509	7.766	2.509	2.387e-02	0.239	-3.512	IFI27	interferon, alpha-inducible protein 27	14	93646831	NM_005532	3429	14q32	Hs.532634	24	molecular_function biological_process membrane integral to membrane
230024_at	0.290	6.081	2.509	2.388e-02	0.239	-3.512	AARS2	alanyl-tRNA synthetase 2, mitochondrial (putative)	6	-44374440	AI183453	57505	6p21.1	Hs.158381	7	nucleotide binding nucleic acid binding alanine-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix translation alanyl-tRNA aminoacylation ligase activity tRNA aminoacylation	Aminoacyl-tRNA biosynthesis
219366_at	-0.457	6.794	-2.509	2.388e-02	0.239	-3.512	AVEN	apoptosis, caspase activation inhibitor	15	-31945719	NM_020371	57099	15q13.1	Hs.555966	10	protein binding intracellular membrane fraction apoptosis anti-apoptosis membrane
242194_at	0.204	7.223	2.509	2.388e-02	0.239	-3.512	CUL4A	cullin 4A	13	112911086, 112911931	W80462	8451	13q34	Hs.339735	48	G1/S transition of mitotic cell cycle protein binding DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
225919_s_at	-0.296	5.703	-2.509	2.388e-02	0.239	-3.512	C9orf72	chromosome 9 open reading frame 72	9	-27550498, -27536543	AI832598	203228	9p21.2	Hs.493639	4
225215_s_at	-0.295	8.333	-2.509	2.388e-02	0.239	-3.512	MTRF1L	mitochondrial translational release factor 1-like	6	-153350092	BF665339	54516	6q25-q26	Hs.225836 Hs.304818	9	cytoplasm mitochondrion translational termination translation release factor activity, codon specific
207468_s_at	0.241	4.364	2.509	2.388e-02	0.239	-3.512	SFRP5	secreted frizzled-related protein 5	10	-99516497	NM_003015	6425	10q24.1	Hs.279565	14	protein binding extracellular region extracellular space apoptosis establishment or maintenance of cell polarity signal transduction multicellular organismal development visual perception anatomical structure morphogenesis Wnt receptor signaling pathway cell differentiation	Wnt signaling pathway
205508_at	-0.299	7.804	-2.509	2.388e-02	0.239	-3.512	SCN1B	sodium channel, voltage-gated, type I, beta	19	40213373, 40213373	NM_001037	6324	19q13.1	Hs.436646	28	voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport synaptic transmission membrane integral to membrane sodium ion binding
225524_at	0.393	6.136	2.509	2.389e-02	0.239	-3.512	ANTXR2	anthrax toxin receptor 2	4	-81117685, -81041796	AU152178	118429	4q21.21	Hs.162963	22	receptor activity protein binding extracellular region endoplasmic reticulum plasma membrane integral to membrane metal ion binding
209554_at	0.269	5.067	2.509	2.389e-02	0.239	-3.513	CD36	CD36 molecule (thrombospondin receptor)	7	80069439, 80105767, 80105767, 80113580, 80113697	BE968792	948	7q11.2	Hs.120949	173	positive regulation of cell-matrix adhesion low-density lipoprotein receptor activity membrane fraction Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process transport cell adhesion nitric oxide mediated signal transduction blood coagulation high-density lipoprotein binding lipid binding cell surface cell surface positive regulation of foam cell differentiation plasma membrane long-chain fatty acid transport lipid storage cGMP-mediated signaling cholesterol transport platelet alpha granule membrane lipoprotein particle clearance lipoprotein catabolic process lipoprotein transport apoptotic cell clearance transforming growth factor beta binding thrombospondin receptor activity	PPAR signaling pathway ECM-receptor interaction Hematopoietic cell lineage Adipocytokine signaling pathway
224600_at	-0.490	6.679	-2.509	2.389e-02	0.239	-3.513	CGGBP1	CGG triplet repeat binding protein 1	3	-88183789	BE501318	8545	3p12-p11.1	Hs.444818	14	DNA binding double-stranded DNA binding nucleus regulation of transcription
218955_at	-0.235	7.480	-2.509	2.389e-02	0.239	-3.513	BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	8	-37820560	NM_018310	55290	8p11.23	Hs.709301	11	protein binding nucleus transcription factor complex transcription initiation regulation of transcription, DNA-dependent zinc ion binding transcription regulator activity metal ion binding
1553264_a_at	0.237	6.122	2.509	2.390e-02	0.239	-3.513	SYN1	synapsin I	X	-47316243	NM_006950	6853	Xp11.23	Hs.225936	34	actin binding catalytic activity transporter activity ATP binding Golgi apparatus synaptic transmission neurotransmitter secretion synaptic vesicle cell junction synapse
1568604_a_at	-0.302	3.979	-2.509	2.390e-02	0.239	-3.513	CADPS	Ca++-dependent secretion activator	3	-62359061	AI912173	8618	3p14.2	Hs.654933	14	calcium ion binding cytosol exocytosis lipid binding protein transport membrane cell junction cytoplasmic vesicle synapse
225967_s_at	0.274	9.445	2.509	2.391e-02	0.239	-3.513	C17orf89	chromosome 17 open reading frame 89	17	76827705	BF683512	284184	17q25.3	Hs.356545	2
221822_at	-0.398	6.879	-2.508	2.393e-02	0.239	-3.514	CCDC101	coiled-coil domain containing 101	16	28472749	BE544663	112869	16p11.2	Hs.655476	6	nucleus regulation of transcription
230611_at	-0.290	9.547	-2.508	2.394e-02	0.239	-3.515	SYPL2	synaptophysin-like 2	1	109810622	AW271199	284612	1p13.3	Hs.528366	5	transporter activity transport synaptic vesicle membrane integral to membrane
222734_at	0.823	5.471	2.508	2.395e-02	0.239	-3.515	WARS2	tryptophanyl tRNA synthetase 2, mitochondrial	1	-119375361	BF515963	10352	1p13.3-p13.1	Hs.523506	10	nucleotide binding tryptophan-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix tryptophanyl-tRNA aminoacylation ligase activity	Tryptophan metabolism Aminoacyl-tRNA biosynthesis
51226_at	0.229	3.438	2.508	2.395e-02	0.239	-3.515	RBM12B	RNA binding motif protein 12B	8	-94812903	N53536	389677	8q22.1	Hs.192788	3	nucleotide binding RNA binding
202686_s_at	0.314	6.688	2.507	2.397e-02	0.239	-3.516	AXL	AXL receptor tyrosine kinase	19	46416947	NM_021913	558	19q13.1	Hs.590970	49	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding integral to plasma membrane protein amino acid phosphorylation signal transduction membrane transferase activity cellular response to extracellular stimulus
209023_s_at	-0.493	6.548	-2.507	2.398e-02	0.239	-3.516	STAG2	stromal antigen 2	X	122922155, 122923236	BC001765	10735	Xq25	Hs.496710 Hs.624663	18	chromatin protein binding nucleus cytoskeleton cell cycle chromosome segregation mitosis meiosis biological_process cell division	Cell cycle
209498_at	0.258	5.401	2.507	2.399e-02	0.239	-3.516	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	19	-47703297	X16354	634	19q13.2	Hs.512682	97	angiogenesis molecular_function extracellular region membrane fraction plasma membrane plasma membrane integral to plasma membrane homophilic cell adhesion integrin-mediated signaling pathway cell migration
238333_s_at	0.284	5.029	2.506	2.401e-02	0.239	-3.517	MTG1	mitochondrial GTPase 1 homolog (S. cerevisiae)	10	135057610	AI355435	92170	10q26.3	Hs.501578	9	nucleotide binding GTP binding intracellular mitochondrion
223457_at	0.368	4.730	2.506	2.401e-02	0.239	-3.517	COPG2	coatomer protein complex, subunit gamma 2	7	-129933315	AB047847	26958	7q32	Hs.6421	18	structural molecule activity protein binding cytoplasm Golgi apparatus Golgi-associated vesicle intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport membrane vesicle-mediated transport membrane coat COPI vesicle coat cytoplasmic vesicle
230438_at	-0.541	8.051	-2.506	2.402e-02	0.239	-3.517	TBX15	T-box 15	1	-119227188	AI039005	6913	1p11.1	Hs.146196	5	transcription factor activity nucleus regulation of transcription, DNA-dependent
226688_at	-0.399	7.193	-2.506	2.402e-02	0.239	-3.518	C3orf23	chromosome 3 open reading frame 23	3	44354614, 44354947, 44354947	AW003508	285343	3p21.31	Hs.55131	8	mitochondrion
1569323_at	-0.504	4.935	-2.506	2.404e-02	0.239	-3.518	PTPRG	protein tyrosine phosphatase, receptor type, G	3	61522282	BU853579	5793	3p21-p14	Hs.595541 Hs.654488	19	transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine kinase signaling pathway membrane hydrolase activity identical protein binding
242640_at	-0.199	3.773	-2.506	2.405e-02	0.239	-3.518	C19orf55	chromosome 19 open reading frame 55	19	40940883	AA503653	148137	19q13.12	Hs.527982	3
228167_at	0.200	2.915	2.505	2.407e-02	0.239	-3.519	KLHL6	kelch-like 6 (Drosophila)	3	-184688012	AW574798	89857		Hs.659147	6	protein binding
202033_s_at	-0.609	8.597	-2.505	2.407e-02	0.239	-3.519	RB1CC1	RB1-inducible coiled-coil 1	8	-53697570	BG402105	9821	8q11	Hs.196102	29	liver development positive regulation of protein amino acid phosphorylation protein binding nucleus cell cycle JNK cascade heart development negative regulation of apoptosis regulation of transcription positive regulation of cell size
1563478_at	-0.247	3.686	-2.505	2.407e-02	0.239	-3.519	KIAA1671	KIAA1671	22	23753940	AL832019	85379	22q11.23	Hs.419171	4
207305_s_at	-0.344	8.718	-2.505	2.408e-02	0.239	-3.520	KIAA1012	KIAA1012	18	-27663133	NM_014939	22878	18q12.1	Hs.202001	8	Golgi apparatus cis-Golgi network ER to Golgi vesicle-mediated transport vesicle-mediated transport
218930_s_at	-0.599	6.449	-2.505	2.408e-02	0.239	-3.520	TMEM106B	transmembrane protein 106B	7	12217372	NM_018374	54664	7p21.3	Hs.396358	10	molecular_function cellular_component biological_process membrane integral to membrane
217825_s_at	-0.274	4.981	-2.505	2.408e-02	0.239	-3.520	UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)	6	-90093062	AF151039	51465	6q15	Hs.163776	12	nucleotide binding ubiquitin-protein ligase activity ATP binding endoplasmic reticulum membrane integral to membrane ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis Parkinson's disease
1555167_s_at	-0.515	6.552	-2.505	2.409e-02	0.239	-3.520	NAMPT	nicotinamide phosphoribosyltransferase	7	-105675967	BC020691	10135	7q22.3	Hs.489615	98	cytokine activity cytoplasm cytosol signal transduction cell-cell signaling positive regulation of cell proliferation NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity	Nicotinate and nicotinamide metabolism
219930_at	-0.211	4.258	-2.504	2.411e-02	0.239	-3.521	KLF8	Kruppel-like factor 8	X	56275546, 56275594	NM_007250	11279	Xp11.21	Hs.646614	13	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
230807_at	0.251	4.882	2.504	2.411e-02	0.239	-3.521	CCDC151	coiled-coil domain containing 151	19	-11392271	AI807422	115948	19p13.2	Hs.124010	3
209513_s_at	0.319	9.661	2.504	2.412e-02	0.239	-3.521	HSDL2	hydroxysteroid dehydrogenase like 2	9	114182171	BC004331	84263	9q32	Hs.59486	6	binding sterol carrier activity oxidoreductase activity oxidation reduction
225647_s_at	-1.132	4.910	-2.504	2.413e-02	0.239	-3.521	CTSC	cathepsin C	11	-87693628, -87666407	AI246687	1075	11q14.1-q14.3	Hs.128065 Hs.706874	51	cysteine-type endopeptidase activity lysosome proteolysis immune response peptidase activity chloride ion binding	Lysosome
206451_at	-0.243	5.149	-2.504	2.413e-02	0.239	-3.522	TBCCD1	TBCC domain containing 1	3	-187746551, -187746551	NM_018138	55171	3q27.3	Hs.518469	3	binding
214791_at	0.443	5.327	2.504	2.413e-02	0.239	-3.522	SP140L	SP140 nuclear body protein-like	2	230900137	AK023116	93349	2q37.1	Hs.662198	3	DNA binding binding nucleus zinc ion binding metal ion binding
221276_s_at	-0.470	9.068	-2.504	2.414e-02	0.239	-3.522	SYNC	syncoilin, intermediate filament protein	1	-32918093	NM_030786	81493	1p34.3-p33	Hs.712631	6	structural molecule activity protein binding cytoplasm cytosol intermediate filament Z disc sarcolemma intermediate filament-based process synapse perinuclear region of cytoplasm
203404_at	0.320	6.255	2.504	2.415e-02	0.239	-3.522	ARMCX2	armadillo repeat containing, X-linked 2	X	-100796925	NM_014782	9823	Xq21.33-q22.2	Hs.48924	7	binding membrane integral to membrane
219165_at	0.600	8.954	2.503	2.417e-02	0.239	-3.523	PDLIM2	PDZ and LIM domain 2 (mystique)	8	22492587, 22493928, 22493928	NM_021630	64236	8p21.2	Hs.632034	10	protein binding nucleus cytoplasm cytoskeleton zinc ion binding cell surface metal ion binding
204113_at	-0.455	4.814	-2.503	2.417e-02	0.239	-3.523	CUGBP1	CUG triplet repeat, RNA binding protein 1	11	-47446520, -47446520, -47446520	NM_006560	10658	11p11	Hs.632137	34	nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding
220647_s_at	0.244	8.184	2.503	2.418e-02	0.239	-3.523	CHCHD8	coiled-coil-helix-coiled-coil-helix domain containing 8	11	-73261360	NM_016565	51287	11q13.4	Hs.475387	6
201903_at	0.309	10.973	2.502	2.421e-02	0.240	-3.525	UQCRC1	ubiquinol-cytochrome c reductase core protein I	3	-48611435	NM_003365	7384	3p21.3	Hs.119251	18	catalytic activity metalloendopeptidase activity protein binding mitochondrion mitochondrial respiratory chain oxidative phosphorylation mitochondrial electron transport, ubiquinol to cytochrome c proteolysis transport ubiquinol-cytochrome-c reductase activity zinc ion binding aerobic respiration membrane electron transport chain metal ion binding	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
229328_at	0.294	4.274	2.502	2.422e-02	0.240	-3.525	ZNF540	zinc finger protein 540	19	42734147	T90358	163255	19q13.12	Hs.121283	5	DNA binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
205522_at	0.422	5.406	2.502	2.423e-02	0.240	-3.525	HOXD4	homeobox D4	2	176724358	NM_014621	3233	2q31.1	Hs.591609	19	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation sequence-specific DNA binding embryonic skeletal system morphogenesis
221239_s_at	0.242	3.601	2.502	2.423e-02	0.240	-3.525	FCRL2	Fc receptor-like 2	1	-155982147	NM_030764	79368	1q21	Hs.437393	13	receptor activity SH3/SH2 adaptor activity soluble fraction plasma membrane cell-cell signaling integral to membrane
202752_x_at	-0.276	6.835	-2.502	2.424e-02	0.240	-3.526	SLC7A8	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8	14	-22664343, -22664343	NM_012244	23428	14q11.2	Hs.632348	14	protein binding cytoplasm plasma membrane integral to plasma membrane cellular amino acid metabolic process transport response to toxin organic cation transmembrane transporter activity neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity neutral amino acid transport L-amino acid transport toxin transporter activity peptide antigen binding metal ion homeostasis
239273_s_at	0.212	2.789	2.501	2.425e-02	0.240	-3.526	MMP28	matrix metallopeptidase 28	17	-31129621, -31116988	AI927208	79148	17q11-q21.1	Hs.380710	13	metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix proteolysis metabolic process peptidase activity zinc ion binding
230630_at	0.247	4.187	2.501	2.426e-02	0.240	-3.526	AK3L1	adenylate kinase 3-like 1	1	65385819, 65386100, 65386473	AI566130	205	1p31.3	Hs.10862 Hs.592601	10	nucleotide binding adenylate kinase activity ATP binding GTP binding mitochondrion mitochondrial matrix nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity	Purine metabolism Metabolic pathways
223862_at	0.281	4.698	2.501	2.427e-02	0.240	-3.527	GHRL	ghrelin/obestatin prepropeptide	3	-10302433, -10302433	AB035700	51738	3p26-p25	Hs.590080	399	activation of MAPK activity negative regulation of endothelial cell proliferation extracellular region extracellular space glucose metabolic process G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration actin polymerization or depolymerization adult feeding behavior response to hormone stimulus hormone-mediated signaling dendrite development negative regulation of angiogenesis growth hormone-releasing hormone activity protein tyrosine kinase activator activity axon ghrelin receptor binding positive regulation of insulin secretion positive regulation of appetite negative regulation of interleukin-1 beta production positive regulation of multicellular organism growth regulation of cell proliferation negative regulation of circadian sleep/wake cycle, REM sleep negative regulation of tumor necrosis factor biosynthetic process negative regulation of apoptosis response to estrogen stimulus negative regulation of interleukin-6 biosynthetic process positive regulation of circadian sleep/wake cycle, non-REM sleep decidualization negative regulation of inflammatory response cartilage development positive regulation of adrenocorticotropin secretion positive regulation of cortisol secretion positive regulation of synaptogenesis positive regulation of growth hormone secretion positive regulation of growth hormone receptor signaling pathway
235305_s_at	0.351	7.354	2.501	2.427e-02	0.240	-3.527	ECHDC2	enoyl Coenzyme A hydratase domain containing 2	1	-53134491	AI903313	55268	1p32.3	Hs.476319	2	mitochondrion lipid metabolic process fatty acid metabolic process metabolic process lyase activity
209060_x_at	-0.549	5.957	-2.501	2.428e-02	0.240	-3.527	NCOA3	nuclear receptor coactivator 3	20	45564063	AI438999	8202	20q12	Hs.592142	140	transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding
228371_s_at	0.203	3.050	2.501	2.428e-02	0.240	-3.527	C16orf72	chromosome 16 open reading frame 72	16	9093037	BF196007	29035	16p13.2	Hs.221497	3
217953_at	-0.242	2.203	-2.500	2.430e-02	0.240	-3.528	PHF3	PHD finger protein 3	6	64414389	AL050329	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
1559190_s_at	0.380	5.767	2.500	2.430e-02	0.240	-3.528	RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	19	-60247503, -60247503	AL833150	112724	19q13.42	Hs.327631	9	binding oxidoreductase activity oxidation reduction
202451_at	-0.281	6.956	-2.500	2.432e-02	0.240	-3.529	GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	11	18300391	BC000365	2965	11p15.1-p14	Hs.577202	77	regulation of cyclin-dependent protein kinase activity nucleotide-excision repair, DNA damage removal protein binding nucleus nucleoplasm holo TFIIH complex DNA repair transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter response to DNA damage stimulus RNA polymerase II carboxy-terminal domain kinase activity general RNA polymerase II transcription factor activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter	Basal transcription factors Nucleotide excision repair
212828_at	1.194	5.994	2.500	2.433e-02	0.240	-3.529	SYNJ2	synaptojanin 2	6	158322906	AA191573	8871	6q25.3	Hs.434494	18	RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity protein binding membrane dephosphorylation hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
202735_at	0.298	6.521	2.500	2.434e-02	0.240	-3.529	EBP	emopamil binding protein (sterol isomerase)	X	48265107	NM_006579	10682	Xp11.23-p11.22	Hs.30619	19	C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity	Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
1552322_at	0.209	2.160	2.499	2.435e-02	0.240	-3.530	FAM122C	family with sequence similarity 122C	X	133768889	NM_138819	159091	Xq26.3	Hs.269127	3
218813_s_at	-0.331	5.345	-2.499	2.436e-02	0.240	-3.530	SH3GLB2	SH3-domain GRB2-like endophilin B2	9	-130810133	NM_020145	56904	9q34	Hs.460238	13	protein binding nucleus nucleolus cytoplasm	Endocytosis
206190_at	-0.243	4.064	-2.499	2.437e-02	0.240	-3.530	GPR17	G protein-coupled receptor 17	2	128119908	NM_005291	2840	2q21	Hs.46453 Hs.688940	8	receptor activity G-protein coupled receptor activity chemokine receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway purinergic nucleotide receptor activity, G-protein coupled
201051_at	0.286	9.005	2.499	2.438e-02	0.240	-3.531	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	15	-66857930	BE560202	8125	15q22.3-q23	Hs.458747	44	protein binding nucleus cytoplasm endoplasmic reticulum nucleocytoplasmic transport nucleocytoplasmic transport intracellular signaling cascade regulation of transcription perinuclear region of cytoplasm
238423_at	0.366	6.617	2.499	2.439e-02	0.240	-3.531	SYTL3	synaptotagmin-like 3	6	158991033	AI674404	94120	6q25.3	Hs.436977	6	protein binding intracellular protein transport zinc ion binding membrane Rab GTPase binding
201857_at	-0.226	9.409	-2.498	2.439e-02	0.240	-3.531	ZFR	zinc finger RNA binding protein	5	-32390212	NM_016107	51663	5p13.3	Hs.435231	6	DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding
222234_s_at	0.430	5.614	2.498	2.440e-02	0.240	-3.531	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1	16	-88598779, -88598779	AK022644	79007	16q24.3	Hs.301394	5	protein binding cytoplasm
203758_at	0.382	5.534	2.498	2.440e-02	0.240	-3.531	CTSO	cathepsin O	4	-157064719	AV729484	1519	4q31-q32	Hs.75262	6	cysteine-type endopeptidase activity proteolysis peptidase activity	Lysosome
205245_at	0.248	6.576	2.498	2.441e-02	0.240	-3.532	PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	16	66252351	NM_016948	50855	16q22.1	Hs.112933	30	ruffle nucleus cytoplasm plasma membrane tight junction cell cycle transcription factor binding viral reproduction Rho GTPase binding cell junction GTP-dependent protein binding cell-cell junction maintenance cell division	Endocytosis Tight junction
52255_s_at	0.259	6.219	2.498	2.442e-02	0.240	-3.532	COL5A3	collagen, type V, alpha 3	19	-9931236	AI984221	50509	19p13.2	Hs.235368	12	extracellular matrix structural constituent collagen binding extracellular region collagen collagen type V cell adhesion cell-matrix adhesion heparin binding collagen fibril organization skin development	Focal adhesion ECM-receptor interaction
228055_at	0.326	4.243	2.498	2.442e-02	0.240	-3.532	NAPSB	napsin B aspartic peptidase pseudogene	19	-55528868	AI763426	256236	19q13.33	Hs.636624	4
201842_s_at	0.851	6.507	2.498	2.443e-02	0.240	-3.533	EFEMP1	EGF-containing fibulin-like extracellular matrix protein 1	2	-55946605, -55946605	AI826799	2202	2p16	Hs.76224	31	calcium ion binding protein binding extracellular region proteinaceous extracellular matrix visual perception
212436_at	-0.229	5.552	-2.498	2.444e-02	0.240	-3.533	TRIM33	tripartite motif-containing 33	1	-114736921	AI967961	51592	1p13.1	Hs.26837	12	DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding
205571_at	0.261	7.143	2.497	2.444e-02	0.240	-3.533	LIPT1	lipoyltransferase 1	2	99137849	NM_015929	51601	2q11.2	Hs.590896	5	mitochondrion protein modification process lipid metabolic process acyltransferase activity protein lipoylation transferase activity	Lipoic acid metabolism Metabolic pathways
218466_at	-0.255	6.675	-2.497	2.446e-02	0.240	-3.534	TBC1D17	TBC1 domain family, member 17	19	55072640	NM_024682	79735	19q13.33	Hs.631587	7	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
203357_s_at	-0.512	5.769	-2.497	2.447e-02	0.240	-3.534	CAPN7	calpain 7	3	15222736	NM_014296	23473	3p24	Hs.631920	6	calcium-dependent cysteine-type endopeptidase activity intracellular nucleus proteolysis peptidase activity cysteine-type peptidase activity
233849_s_at	-0.528	6.053	-2.497	2.448e-02	0.240	-3.535	ARHGAP5	Rho GTPase activating protein 5	14	31616245	AK023014	394	14q12	Hs.592313	19	GTPase activity GTPase activator activity Rho GTPase activator activity GTP binding intracellular cytoplasm cell adhesion signal transduction small GTPase mediated signal transduction Rho protein signal transduction membrane SH2 domain binding	Focal adhesion Leukocyte transendothelial migration
1554334_a_at	-0.711	8.170	-2.497	2.448e-02	0.240	-3.535	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	15	76343541, 76344043, 76345614	BC031044	55466	15q25.1	Hs.513053	5	protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding
1557570_a_at	-0.186	2.364	-2.497	2.449e-02	0.240	-3.535	LOC285084	hypothetical protein LOC285084	2		AA416910	285084	2q31.1	Hs.275398
242149_at	-0.513	6.084	-2.496	2.450e-02	0.240	-3.535	C18orf19	chromosome 18 open reading frame 19	18	-13653345	R02709	125228	18p11.21	Hs.13034	3	membrane integral to membrane
204589_at	0.416	7.466	2.496	2.450e-02	0.240	-3.535	NUAK1	NUAK family, SNF1-like kinase, 1	12	-104981254	NM_014840	9891	12q23.3	Hs.719171	13	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
204059_s_at	0.474	9.227	2.496	2.450e-02	0.240	-3.535	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	6	-83976828	NM_002395	4199	6q12	Hs.21160	24	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway
205647_at	-0.411	5.376	-2.496	2.450e-02	0.240	-3.535	RAD52	RAD52 homolog (S. cerevisiae)	12	-891515	NM_002879	5893	12p13-p12.2	Hs.709202	57	double-strand break repair via homologous recombination DNA binding protein binding nucleus nucleoplasm mitotic recombination response to DNA damage stimulus reciprocal meiotic recombination	Homologous recombination
209501_at	0.315	5.858	2.496	2.450e-02	0.240	-3.535	CDR2	cerebellar degeneration-related protein 2, 62kDa	16	-22264757	AL582414	1039	16p12.3	Hs.513430	14	molecular_function protein binding nucleus cytoplasm
202363_at	0.685	6.012	2.496	2.451e-02	0.240	-3.536	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	5	-136338885	AF231124	6695	5q31	Hs.643338	15	calcium ion binding extracellular region proteinaceous extracellular matrix cell motion cell adhesion signal transduction multicellular organismal development nervous system development cell proliferation
227429_at	0.241	5.984	2.496	2.451e-02	0.240	-3.536	EFCAB4A	EF-hand calcium binding domain 4A	11	817584	AI683694	283229	11p15.5	Hs.660936 Hs.708975	4	calcium ion binding
205600_x_at	0.310	5.285	2.496	2.451e-02	0.240	-3.536	HOXB5	homeobox B5	17	-44023617	AI052747	3215	17q21.3	Hs.654456	25	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anatomical structure morphogenesis anterior/posterior pattern formation sequence-specific DNA binding endothelial cell differentiation embryonic skeletal system morphogenesis
205463_s_at	-0.603	6.096	-2.496	2.452e-02	0.240	-3.536	PDGFA	platelet-derived growth factor alpha polypeptide	7	-503424	NM_002607	5154	7p22	Hs.535898	79	cell activation platelet-derived growth factor receptor binding platelet-derived growth factor receptor binding collagen binding extracellular region extracellular region extracellular space cell-cell signaling growth factor activity embryonic development cell surface negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation regulation of smooth muscle cell migration membrane positive regulation of cell migration platelet dense granule lumen regulation of actin cytoskeleton organization wound healing protein homodimerization activity cell surface binding positive regulation of DNA replication protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding negative chemotaxis	MAPK signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Glioma Prostate cancer Melanoma
215990_s_at	-0.932	6.554	-2.496	2.453e-02	0.240	-3.536	BCL6	B-cell CLL/lymphoma 6	3	-188921858, -188921858, -188921858	S67779	604	3q27	Hs.478588	139	protein import into nucleus, translocation negative regulation of transcription from RNA polymerase II promoter cell morphogenesis negative regulation of cell-matrix adhesion regulation of germinal center formation negative regulation of T-helper 2 type immune response negative regulation of B cell apoptosis transcription factor activity protein binding intracellular nucleus replication fork response to DNA damage stimulus spermatogenesis protein localization zinc ion binding negative regulation of cell proliferation transcription repressor activity transcription repressor activity actin cytoskeleton organization B cell differentiation negative regulation of cell growth positive regulation of B cell proliferation chromatin DNA binding regulation of Rho GTPase activity negative regulation of mast cell cytokine production negative regulation of Rho protein signal transduction positive regulation of apoptosis negative regulation of apoptosis regulation of memory T cell differentiation sequence-specific DNA binding regulation of transcription negative regulation of cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of S phase of mitotic cell cycle metal ion binding negative regulation of isotype switching to IgE isotypes erythrocyte development regulation of inflammatory response positive regulation of cell motion
1554589_at	0.291	4.740	2.496	2.454e-02	0.240	-3.537	LENG9	leukocyte receptor cluster (LRC) member 9	19	-59664790	BC015921	94059	19q13.4	Hs.590976	3	nucleic acid binding catalytic activity intracellular zinc ion binding RNA metabolic process metal ion binding
229340_at	-0.233	5.796	-2.495	2.456e-02	0.240	-3.537	NKAPL	NFKB activating protein-like	6	28335076	BF592882	222698	6p22.1	Hs.239181	3
202288_at	-0.209	5.971	-2.495	2.457e-02	0.241	-3.538	MTOR	mechanistic target of rapamycin (serine/threonine kinase)	1	-11089175	U88966	2475	1p36.2	Hs.338207	317	nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum Golgi apparatus cytosol phosphoinositide 3-kinase complex signal transduction response to nutrient endomembrane system membrane cell growth kinase activity phosphotransferase activity, alcohol group as acceptor protein catabolic process TOR signaling pathway TORC1 complex TORC2 complex regulation of actin cytoskeleton organization response to amino acid stimulus protein amino acid autophosphorylation phosphoprotein binding	ErbB signaling pathway mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Pathways in cancer Glioma Prostate cancer Acute myeloid leukemia
214705_at	-0.740	4.385	-2.495	2.458e-02	0.241	-3.538	INADL	InaD-like (Drosophila)	1	61980736	AJ001306	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
203808_at	0.188	3.646	2.494	2.459e-02	0.241	-3.538	AKT2	v-akt murine thymoma viral oncogene homolog 2	19	-45428063	M95936	208	19q13.1-q13.2	Hs.631535	110	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytosol protein modification process protein amino acid phosphorylation insulin receptor signaling pathway negative regulation of plasma membrane long-chain fatty acid transport positive regulation of glucose metabolic process transferase activity positive regulation of fatty acid beta-oxidation positive regulation of glycogen biosynthetic process positive regulation of glucose import	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Tight junction Toll-like receptor signaling pathway Jak-STAT signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
229235_at	-0.368	7.659	-2.494	2.459e-02	0.241	-3.538	ZCCHC11	zinc finger, CCHC domain containing 11	1	-52661535	AI983432	23318	1p32.3	Hs.655407	7	nucleic acid binding protein binding intracellular nucleus cytoplasm zinc ion binding nucleotidyltransferase activity metal ion binding
210321_at	0.309	4.655	2.494	2.460e-02	0.241	-3.539	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	14	-24145532	M36118	2999	14q11.2	Hs.348264	17	serine-type endopeptidase activity cytoplasm proteolysis apoptosis peptidase activity cytolysis
205399_at	0.452	5.463	2.494	2.461e-02	0.241	-3.539	DCLK1	doublecortin-like kinase 1	13	-35241122	NM_004734	9201	13q13	Hs.507755 Hs.717124	15	nucleotide binding protein serine/threonine kinase activity receptor signaling protein activity protein binding ATP binding integral to plasma membrane protein amino acid phosphorylation intracellular signaling cascade multicellular organismal development central nervous system development endosome transport transferase activity cell differentiation
224057_s_at	0.365	8.536	2.494	2.461e-02	0.241	-3.539	THAP4	THAP domain containing 4	2	-242172492, -1615	BC000767	51078	2q37.3	Hs.435759 Hs.645463	9	DNA binding zinc ion binding metal ion binding
1558346_at	-0.258	4.244	-2.494	2.461e-02	0.241	-3.539	COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	3	-120871061	BG535811	10063	3q13.33	Hs.534383	19	cytoplasm mitochondrion mitochondrial intermembrane space generation of precursor metabolites and energy copper ion transport copper chaperone activity metal ion binding	Oxidative phosphorylation Metabolic pathways
214647_s_at	0.190	3.693	2.494	2.462e-02	0.241	-3.540	HFE	hemochromatosis	6	26195487	BG402460	3077	6p21.3	Hs.233325	592	antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome
238222_at	0.242	4.341	2.494	2.462e-02	0.241	-3.540	GKN2	gastrokine 2	2	-69025867	AI821357	200504	2p13.3	Hs.16757	8	extracellular region
220373_at	0.242	3.647	2.494	2.463e-02	0.241	-3.540	DCHS2	dachsous 2 (Drosophila)	4	-155627044, -155463255, -155374976	NM_017639	54798	4q31.3	Hs.655664 Hs.712046	6	calcium ion binding protein binding cell adhesion homophilic cell adhesion membrane integral to membrane
224974_at	-0.396	5.141	-2.494	2.463e-02	0.241	-3.540	SUDS3	suppressor of defective silencing 3 homolog (S. cerevisiae)	12	117298740	AK024460	64426	12q24.23	Hs.416630 Hs.602312	9	protein binding negative regulation of transcription chromatin modification Sin3 complex histone deacetylase binding
203680_at	0.616	5.599	2.493	2.465e-02	0.241	-3.541	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	7	106472413	NM_002736	5577	7q22	Hs.433068	48	nucleotide binding regulation of protein amino acid phosphorylation cAMP-dependent protein kinase complex fatty acid metabolic process learning cAMP-dependent protein kinase regulator activity hormone-mediated signaling cAMP binding	Apoptosis Insulin signaling pathway
202074_s_at	-0.388	11.092	-2.493	2.466e-02	0.241	-3.541	OPTN	optineurin	10	13182087	NM_021980	10133	10p13	Hs.332706	65	protein targeting to Golgi cytoplasm Golgi apparatus Golgi organization signal transduction protein C-terminus binding cell death cellular protein localization Golgi to plasma membrane protein transport perinuclear region of cytoplasm
218910_at	0.207	5.975	2.493	2.466e-02	0.241	-3.541	ANO10	anoctamin 10	3	-43382821	NM_018075	55129	3p22.1	Hs.656657	3	ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex
221322_at	0.203	2.626	2.493	2.466e-02	0.241	-3.541	NPVF	neuropeptide VF precursor	7	-25230715	NM_022150	64111	7p21-p15	Hs.60473	8	G-protein coupled receptor activity protein binding extracellular region neuropeptide signaling pathway membrane
204243_at	-0.246	6.562	-2.493	2.467e-02	0.241	-3.541	RLF	rearranged L-myc fusion	1	40399627	NM_012421	6018	1p32	Hs.205627	10	transcription factor activity protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
218404_at	0.442	4.568	2.493	2.468e-02	0.241	-3.542	SNX10	sorting nexin 10	7	26298039	NM_013322	29887	7p15.2	Hs.719227	6	protein binding cell communication protein transport phosphoinositide binding
211807_x_at	0.204	5.114	2.493	2.468e-02	0.241	-3.542	PCDHGB5	protocadherin gamma subfamily B, 5	5	140757878, 140757878	AF152521	56101	5q31	Hs.368160	6	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
202210_x_at	0.188	6.828	2.492	2.469e-02	0.241	-3.542	GSK3A	glycogen synthase kinase 3 alpha	19	-47426177	NM_019884	2931	19q13.2	Hs.466828	52	nucleotide binding glycogen synthase kinase 3 activity protein binding ATP binding cytosol cytosol protein amino acid phosphorylation negative regulation of UDP-glucose catabolic process transferase activity protein kinase A catalytic subunit binding negative regulation of glucose import negative regulation of insulin receptor signaling pathway tau-protein kinase activity negative regulation of transferase activity	Chemokine signaling pathway
208671_at	-0.414	9.911	-2.492	2.469e-02	0.241	-3.542	SERINC1	serine incorporator 1	6	-122806191	AF164794	57515	6q22.31	Hs.146668	9	endoplasmic reticulum endoplasmic reticulum membrane plasma membrane lipid metabolic process phosphatidylserine metabolic process sphingolipid metabolic process phospholipid biosynthetic process L-serine transmembrane transporter activity L-serine transport integral to membrane positive regulation of transferase activity
211946_s_at	-0.269	8.838	-2.492	2.469e-02	0.241	-3.542	BAT2D1	BAT2 domain containing 1	1	169721289	AL096857	23215	1q23.3	Hs.494614	5
228143_at	0.332	3.294	2.492	2.470e-02	0.241	-3.543	CP	ceruloplasmin (ferroxidase)	3	-150372979	AI684991	1356	3q23-q25	Hs.558314	95	ferroxidase activity copper ion binding extracellular region extracellular space ion transport copper ion transport cellular iron ion homeostasis aging response to nutrient oxidoreductase activity anchored to plasma membrane metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
208147_s_at	0.265	2.458	2.492	2.471e-02	0.241	-3.543	CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	10	-96786518	NM_030878	1558	10q23.33	Hs.709188	97	monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity	Arachidonic acid metabolism Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
214515_at	0.233	4.024	2.492	2.471e-02	0.241	-3.543	OR1E1	olfactory receptor, family 1, subfamily E, member 1	17	-3247509	NM_003553	8387	17p13.3	Hs.278485	7	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
221166_at	0.212	4.274	2.492	2.472e-02	0.241	-3.543	FGF23	fibroblast growth factor 23	12	-4347653	NM_020638	8074	12p13.3	Hs.287370	83	extracellular region extracellular region extracellular space growth factor activity fibroblast growth factor receptor signaling pathway cell differentiation regulation of bone mineralization cellular phosphate ion homeostasis	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
230745_s_at	0.301	5.237	2.492	2.473e-02	0.241	-3.544	TOX3	TOX high mobility group box family member 3	16	-51029418, -51029418	AI347147	27324	16q12.1	Hs.460789	11	DNA binding nucleus
223448_x_at	0.265	8.616	2.491	2.477e-02	0.241	-3.545	MRPS22	mitochondrial ribosomal protein S22	3	140545550	AF063603	56945	3q23	Hs.75724	13	molecular_function structural constituent of ribosome protein binding mitochondrion mitochondrial small ribosomal subunit ribosome biological_process
219815_at	0.241	5.564	2.490	2.478e-02	0.241	-3.546	GAL3ST4	galactose-3-O-sulfotransferase 4	7	-99594800	NM_024637	79690	7q22.1	Hs.44856	10	galactosylceramide sulfotransferase activity membrane fraction Golgi apparatus sulfur metabolic process cell-cell signaling biosynthetic process glycoprotein metabolic process oligosaccharide metabolic process membrane integral to membrane transferase activity proteoglycan biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate binding proteoglycan sulfotransferase activity
202628_s_at	0.271	3.944	2.490	2.482e-02	0.241	-3.547	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	7	100557098	NM_000602	5054	7q21.3-q22	Hs.414795 Hs.713079	700	chronological cell aging protease binding serine-type endopeptidase activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular region plasma membrane blood coagulation peptidase inhibitor activity regulation of cell proliferation fibrinolysis regulation of angiogenesis	p53 signaling pathway Complement and coagulation cascades
220019_s_at	0.226	4.089	2.490	2.483e-02	0.241	-3.547	ZNF224	zinc finger protein 224	19	49290336	NM_005774	7767	19q13.2	Hs.585869	10	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229312_s_at	-0.465	8.507	-2.490	2.483e-02	0.241	-3.547	GKAP1	G kinase anchoring protein 1	9	-85544156	BF434321	80318	9q21.32	Hs.522255	5	protein binding Golgi apparatus signal transduction
211475_s_at	0.337	9.594	2.489	2.484e-02	0.241	-3.547	BAG1	BCL2-associated athanogene	9	-33242469	AF116273	573	9p12	Hs.377484	78	receptor signaling protein activity protein binding nucleus cytoplasm cytoskeleton apoptosis anti-apoptosis cell surface receptor linked signal transduction
237091_at	0.329	4.275	2.489	2.484e-02	0.241	-3.548	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)	4	-141761385	AW138788	23158	4q31.21	Hs.480819	11	GTPase activator activity Rab GTPase activator activity calcium ion binding intracellular regulation of Rab GTPase activity
207585_s_at	-0.361	9.646	-2.489	2.484e-02	0.241	-3.548	RPL36AL	ribosomal protein L36a-like	14	-49155156	NM_001001	6166	14q21	Hs.444749	7	structural constituent of ribosome intracellular cytoplasm ribosome translation	Ribosome
201643_x_at	-0.234	8.231	-2.489	2.484e-02	0.241	-3.548	KDM3B	lysine (K)-specific demethylase 3B	5	137716183	NM_016604	51780	5q31	Hs.714832	14	iron ion binding nucleus nucleolus zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
200014_s_at	-0.356	9.034	-2.489	2.486e-02	0.242	-3.548	HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	14	-20747135	NM_004500	3183	14q11.2	Hs.508848	51	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding nucleus spliceosomal complex RNA splicing identical protein binding
213513_x_at	-0.367	10.004	-2.489	2.488e-02	0.242	-3.549	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	2	218790118, 218790364	BG034239	10109	2q36.1	Hs.529303	23	actin binding structural constituent of cytoskeleton protein binding cytoplasm Golgi apparatus Arp2/3 protein complex focal adhesion cell motion positive regulation of actin filament polymerization cell leading edge cell projection	Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
213122_at	-0.398	7.874	-2.488	2.489e-02	0.242	-3.549	TSPYL5	TSPY-like 5	8	-98354889	AI096375	85453	8q22.1	Hs.173094	4	nucleus nucleosome assembly
211276_at	0.234	3.057	2.488	2.489e-02	0.242	-3.549	TCEAL2	transcription elongation factor A (SII)-like 2	X	101267315	AF063606	140597	Xq22.1-q22.3	Hs.401835	6	nucleus regulation of transcription
208089_s_at	-0.420	5.503	-2.488	2.490e-02	0.242	-3.550	TDRD3	tudor domain containing 3	13	59868591, 59869427	NM_030794	81550	13q21.2	Hs.525061	12	nucleic acid binding nucleus cytoplasm
217987_at	-0.369	8.972	-2.488	2.491e-02	0.242	-3.550	ASNSD1	asparagine synthetase domain containing 1	2	190234369	NM_019048	54529	2p24.3-q21.3	Hs.101364	3	asparagine synthase (glutamine-hydrolyzing) activity asparagine biosynthetic process glutamine metabolic process cellular amino acid biosynthetic process
216395_at	0.207	4.850	2.488	2.492e-02	0.242	-3.550	FBXL18	F-box and leucine-rich repeat protein 18	7	-5481953	AL137434	80028	7p22.2	Hs.623974 Hs.706587	5	modification-dependent protein catabolic process
219243_at	0.470	6.319	2.488	2.492e-02	0.242	-3.550	GIMAP4	GTPase, IMAP family member 4	7	149895390	NM_018326	55303	7q36.1	Hs.647101 Hs.648582	11	nucleotide binding GTP binding
239047_at	0.238	4.039	2.487	2.494e-02	0.242	-3.551	FAM122C	family with sequence similarity 122C	X	133768889	AW028188	159091	Xq26.3	Hs.269127	3
205190_at	-0.391	4.379	-2.487	2.495e-02	0.242	-3.552	PLS1	plastin 1 (I isoform)	3	143797918, 143824955	NM_002670	5357	3q23	Hs.203637	10	structural constituent of cytoskeleton calcium ion binding cytoplasm actin filament binding
201783_s_at	-0.220	6.860	-2.487	2.495e-02	0.242	-3.552	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	11	-65177643	NM_021975	5970	11q13	Hs.502875	425	liver development hair follicle development RNA polymerase II transcription factor activity, enhancer binding nucleus nucleoplasm transcription factor complex cytoplasm cytosol anti-apoptosis inflammatory response cellular defense response organ morphogenesis response to organic substance response to UV-B cytokine-mediated signaling pathway protein kinase binding transcription activator binding negative regulation of protein catabolic process phosphate binding identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms positive regulation of interleukin-12 biosynthetic process positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding NF-kappaB binding positive regulation of NF-kappaB transcription factor activity defense response to virus transcription repressor binding response to interleukin-1	MAPK signaling pathway Chemokine signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Pancreatic cancer Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer
237044_s_at	0.294	5.463	2.487	2.495e-02	0.242	-3.552	C10orf41	chromosome 10 open reading frame 41	10	76831291, 76833519	AI480142	100131213	10q22.2	Hs.534598 Hs.599628	4
203456_at	0.255	5.233	2.487	2.497e-02	0.242	-3.552	PRAF2	PRA1 domain family, member 2	X	-48815761	NM_007213	11230	Xp11.23	Hs.29595	7	endosome protein transport L-glutamate transport membrane integral to membrane
1569293_x_at	-0.183	6.258	-2.486	2.499e-02	0.242	-3.553	CROCCL1	ciliary rootlet coiled-coil, rootletin-like 1	1	-16817339	BC015342	84809	1p36.13	Hs.631865	2
217822_at	-0.280	8.198	-2.486	2.499e-02	0.242	-3.553	WBP11	WW domain binding protein 11	12	-14830678	NM_016312	51729	12p12.3	Hs.655138	13	single-stranded DNA binding protein binding nucleus cytoplasm rRNA processing mRNA processing RNA splicing protein phosphatase type 1 regulator activity nuclear speck
202599_s_at	-0.650	8.694	-2.486	2.500e-02	0.242	-3.553	NRIP1	nuclear receptor interacting protein 1	21	-15255426	NM_003489	8204	21q11.2	Hs.155017	47	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter ovarian follicle rupture transcription coactivator activity transcription coactivator activity transcription corepressor activity receptor binding nucleus lipid storage estrogen receptor binding androgen receptor signaling pathway ovulation nuclear hormone receptor binding glucocorticoid receptor binding histone deacetylase binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter retinoid X receptor binding androgen receptor binding
216708_x_at	0.307	3.339	2.486	2.500e-02	0.242	-3.553	IGL@	immunoglobulin lambda locus	22		D84143	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
223828_s_at	0.216	3.883	2.486	2.500e-02	0.242	-3.553	LGALS12	lectin, galactoside-binding, soluble, 12	11	63030099, 63032034	AF222694	85329	11q13	Hs.502774	5	sugar binding nucleus mitochondrion apoptosis induction of apoptosis by intracellular signals lactose binding
229058_at	0.278	5.607	2.486	2.502e-02	0.242	-3.554	ANKRD16	ankyrin repeat domain 16	10	-5960056, -5943696	AI826110	54522	10p15.1	Hs.289828	4
202541_at	-0.373	7.896	-2.486	2.502e-02	0.242	-3.554	AIMP1	aminoacyl tRNA synthetase complex-interacting multifunctional protein 1	4	107456215, 107456301, 107457112	BF589679	9255	4q24	Hs.591680	35	tRNA binding negative regulation of endothelial cell proliferation cytokine activity extracellular region extracellular space nucleus endoplasmic reticulum Golgi apparatus cytosol tRNA aminoacylation for protein translation chemotaxis inflammatory response signal transduction cell-cell signaling aminoacyl-tRNA synthetase multienzyme complex secretory granule protein homodimerization activity cell surface binding leukocyte migration
228968_at	0.206	6.053	2.485	2.504e-02	0.242	-3.555	ZNF449	zinc finger protein 449	X	134306361	AI888786	203523	Xq26.3	Hs.28780	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
240325_x_at	0.250	5.390	2.485	2.504e-02	0.242	-3.555	LOC442142	hypothetical LOC442142	5		AI953040	442142	5q33.3
221527_s_at	-0.486	7.473	-2.485	2.504e-02	0.242	-3.555	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AF196185	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
214357_at	0.722	5.129	2.485	2.505e-02	0.242	-3.555	C1orf105	chromosome 1 open reading frame 105	1	170656452	AL035295	92346	1q24.3	Hs.517991	4
225364_at	0.248	5.872	2.485	2.505e-02	0.242	-3.555	STK4	serine/threonine kinase 4	20	43028533	BE222274	6789	20q11.2-q13.2	Hs.472838	38	nucleotide binding magnesium ion binding cell morphogenesis protein serine/threonine kinase activity ATP binding nucleus cytoplasm signal transduction protein kinase cascade transcription factor binding transferase activity peptidyl-serine phosphorylation protein homodimerization activity positive regulation of apoptosis protein amino acid autophosphorylation	MAPK signaling pathway Pathways in cancer Non-small cell lung cancer
211980_at	0.540	9.054	2.485	2.505e-02	0.242	-3.555	COL4A1	collagen, type IV, alpha 1	13	-109599310	AI922605	1282	13q34	Hs.17441	83	extracellular matrix structural constituent binding extracellular region collagen collagen type IV	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
202147_s_at	-0.633	7.163	-2.485	2.506e-02	0.242	-3.555	IFRD1	interferon-related developmental regulator 1	7	111850461, 111877750	NM_001550	3475	7q22-q31	Hs.7879	23	binding nucleus multicellular organismal development myoblast cell fate determination adult somatic muscle development muscle cell differentiation
216178_x_at	-0.601	7.325	-2.485	2.506e-02	0.242	-3.556	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	10	-33236244, -33229251, -33229251, -33229251	AA215854	3688	10p11.2	Hs.643813	512	G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation	Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
227007_at	0.382	4.439	2.485	2.508e-02	0.242	-3.556	TMCO4	transmembrane and coiled-coil domains 4	1	-19881292	AI972419	255104	1p36.13	Hs.656313	2	membrane integral to membrane
227447_at	-0.358	7.743	-2.484	2.511e-02	0.242	-3.557	SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	5	54639332	AA525163	23517	5q11.2	Hs.274531	19	nucleotide binding nucleic acid binding helicase activity protein binding ATP binding nucleus spliceosomal complex nucleolus mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RNA degradation
221400_at	0.242	3.922	2.484	2.511e-02	0.242	-3.557	MYO3A	myosin IIIA	10	26263007	NM_017433	53904	10p11.1	Hs.662630	14	nucleotide binding actin binding protein serine/threonine kinase activity calmodulin binding ATP binding cytoplasm cytoskeleton visual perception sensory perception of sound myosin complex transferase activity filopodium actin-dependent ATPase activity filamentous actin ADP binding protein amino acid autophosphorylation response to stimulus plus-end directed microfilament motor activity
234672_s_at	-0.310	6.097	-2.484	2.512e-02	0.242	-3.557	TMEM48	transmembrane protein 48	1	-54005975	AL354612	55706	1p32.3	Hs.476525	10	nucleus nuclear pore protein transport membrane integral to membrane structural constituent of nuclear pore nuclear pore distribution mRNA transport nuclear pore complex assembly intracellular protein transmembrane transport
226899_at	0.610	5.673	2.484	2.513e-02	0.242	-3.558	UNC5B	unc-5 homolog B (C. elegans)	10	72642303	AK022859	219699	10q22.1	Hs.522997	12	receptor activity protein binding apoptosis signal transduction multicellular organismal development membrane integral to membrane	Axon guidance
216899_s_at	0.571	5.060	2.484	2.513e-02	0.242	-3.558	SKAP2	src kinase associated phosphoprotein 2	7	-26673212	AC003999	8935	7p21-p15	Hs.200770 Hs.644804	19	SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation
204831_at	-0.404	6.772	-2.483	2.513e-02	0.242	-3.558	CDK8	cyclin-dependent kinase 8	13	25726755	R59697	1024	13q12	Hs.382306	38	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation RNA polymerase II carboxy-terminal domain kinase activity transferase activity regulation of transcription
229230_at	0.193	3.513	2.483	2.513e-02	0.242	-3.558	OSTalpha	organic solute transporter alpha	3	197427779	AA702685	200931	3q29	Hs.630585	11	transporter activity plasma membrane transport integral to membrane
211474_s_at	0.271	8.997	2.483	2.516e-02	0.242	-3.559	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6	6	-2893391	BC004948	5269	6p25	Hs.519523	21	serine-type endopeptidase inhibitor activity protein binding cytoplasm cytosol peptidase inhibitor activity
218625_at	0.398	6.380	2.483	2.517e-02	0.242	-3.559	NRN1	neuritin 1	6	-5943231	NM_016588	51299	6p25.1	Hs.103291	7	plasma membrane anchored to membrane
209419_at	0.169	3.388	2.482	2.518e-02	0.242	-3.560	THOC5	THO complex 5	22	-28234155, -28234155	AB023200	8563	22q12.2	Hs.75361	18	protein binding nucleus cytoplasm cell differentiation negative regulation of macrophage differentiation
244345_at	0.221	2.913	2.482	2.518e-02	0.242	-3.560	CADM1	cell adhesion molecule 1	11	-114549554	AI627453	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
218108_at	-0.270	6.381	-2.482	2.520e-02	0.243	-3.560	UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	14	92743153	NM_018108	55148	14q32.12	Hs.648806	7	molecular_function ubiquitin-protein ligase activity protein binding biological_process zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
234452_at	0.226	5.231	2.482	2.521e-02	0.243	-3.561	HIBADH	3-hydroxyisobutyrate dehydrogenase	7	-27531585	AK025558	11112	7p15.2	Hs.406758	9	phosphogluconate dehydrogenase (decarboxylating) activity binding mitochondrion pentose-phosphate shunt valine metabolic process 3-hydroxyisobutyrate dehydrogenase activity oxidoreductase activity NAD or NADH binding oxidation reduction	Valine, leucine and isoleucine degradation Metabolic pathways
223432_at	0.294	5.329	2.482	2.522e-02	0.243	-3.561	OSBP2	oxysterol binding protein 2	22	29420792	BE501253	23762	22q12.2	Hs.517546	11	lipid transport steroid metabolic process membrane
219307_at	0.355	6.491	2.482	2.522e-02	0.243	-3.561	PDSS2	prenyl (decaprenyl) diphosphate synthase, subunit 2	6	-107580453	NM_020381	57107	6q21	Hs.718509	9	trans-hexaprenyltranstransferase activity ubiquinone biosynthetic process isoprenoid biosynthetic process transferase activity protein heterodimerization activity	Terpenoid backbone biosynthesis
203857_s_at	0.322	5.307	2.482	2.523e-02	0.243	-3.561	PDIA5	protein disulfide isomerase family A, member 5	3	124268654	NM_006810	10954	3q21.1	Hs.477352	9	protein disulfide isomerase activity endoplasmic reticulum endoplasmic reticulum lumen protein folding response to stress oxidoreductase activity isomerase activity cell redox homeostasis oxidation reduction
202957_at	0.398	4.313	2.481	2.524e-02	0.243	-3.562	HCLS1	hematopoietic cell-specific Lyn substrate 1	3	-122832935	NM_005335	3059	3q13	Hs.14601	33	transcription factor activity protein binding nucleus DNA-directed RNA polymerase II, core complex cytoplasm mitochondrion regulation of transcription, DNA-dependent intracellular signaling cascade positive regulation of cell proliferation response to hormone stimulus membrane SH3 domain binding erythrocyte differentiation positive regulation of tyrosine phosphorylation of STAT protein	Tight junction Pathogenic Escherichia coli infection - EHEC
201087_at	-0.267	7.223	-2.481	2.526e-02	0.243	-3.562	PXN	paxillin	12	-119132632, -119132632	NM_002859	5829	12q24.31	Hs.446336	140	protein binding cytoplasm cytoskeleton microtubule associated complex plasma membrane focal adhesion cell adhesion cell-matrix adhesion signal transduction signal complex assembly zinc ion binding vinculin binding lamellipodium cell junction cellular response to reactive oxygen species metal ion binding	Chemokine signaling pathway VEGF signaling pathway Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
209731_at	0.246	5.702	2.481	2.526e-02	0.243	-3.563	NTHL1	nth endonuclease III-like 1 (E. coli)	16	-2029816	U79718	4913	16p13.3	Hs.66196	32	oxidized pyrimidine base lesion DNA N-glycosylase activity DNA binding double-stranded DNA binding endonuclease activity iron ion binding protein binding intracellular nucleus nucleoplasm mitochondrion nucleotide-excision repair, DNA incision, 5'-to lesion response to DNA damage stimulus metabolic process hydrolase activity, acting on glycosyl bonds lyase activity DNA N-glycosylase activity depyrimidination metal ion binding 4 iron, 4 sulfur cluster binding	Base excision repair
227522_at	-0.710	10.442	-2.481	2.527e-02	0.243	-3.563	CMBL	carboxymethylenebutenolidase homolog (Pseudomonas)	5	-10330706	AA209487	134147	5p15.2	Hs.192586	4	protein binding hydrolase activity	gamma-Hexachlorocyclohexane degradation Fluorobenzoate degradation 1,4-Dichlorobenzene degradation Metabolic pathways
214053_at	-0.784	5.754	-2.480	2.528e-02	0.243	-3.563	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	2	-211948686	AW772192	2066	2q33.3-q34	Hs.390729	112	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway nervous system development heart development cell proliferation membrane integral to membrane basolateral plasma membrane transferase activity cell fate commitment	ErbB signaling pathway Calcium signaling pathway Endocytosis
221647_s_at	0.252	7.357	2.480	2.530e-02	0.243	-3.564	RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	11	198529	AL136935	60626	11p15.5	Hs.592292	16	in utero embryonic development G-protein alpha-subunit binding guanyl-nucleotide exchange factor activity GTPase activator activity cytoplasm visual learning response to light stimulus
207254_at	0.195	4.682	2.480	2.532e-02	0.243	-3.565	SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1	13	-98134057	NM_005073	6564	13q33-q34	Hs.436893	48	transporter activity proton-dependent oligopeptide secondary active transmembrane transporter activity membrane fraction integral to plasma membrane oligopeptide transport digestion protein transport oligopeptide transporter activity symporter activity peptide:hydrogen symporter activity membrane
202704_at	-0.425	10.582	-2.480	2.532e-02	0.243	-3.565	TOB1	transducer of ERBB2, 1	17	-46294585	AA675892	10140	17q21	Hs.709952 Hs.714409 Hs.719207	29	transcription corepressor activity SH3/SH2 adaptor activity cytoplasm SMAD protein nuclear translocation negative regulation of cell proliferation negative regulation of BMP signaling pathway negative regulation of osteoblast differentiation SMAD binding
218093_s_at	-0.434	8.468	-2.480	2.532e-02	0.243	-3.565	ANKRD10	ankyrin repeat domain 10	13	-110328887	NM_017664	55608	13q34	Hs.525163	2
217700_at	0.252	6.332	2.479	2.533e-02	0.243	-3.565	CNPY4	canopy 4 homolog (zebrafish)	7	99555200	AI818951	245812	7q22.1	Hs.632293	5	extracellular region
203621_at	0.224	11.577	2.479	2.534e-02	0.243	-3.565	NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	3	180805268	NM_002492	4711	3q26.33	Hs.718447	9	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1552334_at	0.339	4.687	2.479	2.534e-02	0.243	-3.565	TRIOBP	TRIO and F-actin binding protein	22	36422940, 36472186, 36472186	BG571343	11078	22q13.1	Hs.533030	20	actin binding protein binding nucleus cytoplasm actin cytoskeleton GTP-Rho binding actin modification myosin II binding barbed-end actin filament capping
225616_at	0.371	6.771	2.479	2.535e-02	0.243	-3.566	SPRYD4	SPRY domain containing 4	12	55148567	AI570493	283377	12q13.3	Hs.128676	4	nucleus
229089_at	0.242	5.952	2.479	2.535e-02	0.243	-3.566	ZNF509	zinc finger protein 509	4	4342824	BF061904	166793	4p16.3	Hs.419997	3	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
218974_at	-0.366	8.976	-2.479	2.535e-02	0.243	-3.566	SOBP	sine oculis binding protein homolog (Drosophila)	6	107918009	NM_018013	55084	6q21	Hs.445244	4	zinc ion binding metal ion binding
232587_at	0.284	4.458	2.479	2.537e-02	0.243	-3.567	EML4	echinoderm microtubule associated protein like 4	2	42249993	AI208611	27436	2p22-p21	Hs.593614	22	molecular_function protein binding cytoplasm microtubule microtubule-based process mitosis
207589_at	0.218	3.016	2.479	2.537e-02	0.243	-3.567	ADRA1B	adrenergic, alpha-1B-, receptor	5	159276317	NM_000679	147	5q23-q32	Hs.368632	36	integral to membrane of membrane fraction blood vessel remodeling response to amphetamine vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure positive regulation of heart rate by epinephrine-norepinephrine positive regulation of the force of heart contraction by epinephrine-norepinephrine receptor activity G-protein coupled receptor activity adrenoceptor activity alpha1-adrenergic receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger protein kinase cascade cell-cell signaling multicellular organismal development adult heart development locomotory behavior cell proliferation visual learning cell growth organ growth glucose homeostasis response to morphine negative regulation of glycogen catabolic process positive regulation of glycogen catabolic process behavioral response to cocaine	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
219451_at	-0.343	8.703	-2.478	2.539e-02	0.243	-3.567	MSRB2	methionine sulfoxide reductase B2	10	23424432	NM_016064	22921	10p12	Hs.461420	14	protein-methionine-R-oxide reductase activity transcription factor activity mitochondrion peptide-methionine-(S)-S-oxide reductase activity zinc ion binding oxidoreductase activity protein repair metal ion binding oxidation reduction
244547_at	0.241	4.600	2.478	2.540e-02	0.243	-3.567	FLJ25006	uncharacterized serine/threonine-protein kinase SgK494	17	-23959108	AW081561	124923	17q11.2	Hs.514033 Hs.657973	3	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
222119_s_at	-0.312	7.534	-2.478	2.541e-02	0.243	-3.568	FBXO11	F-box protein 11	2	-47899228, -47893491, -47887562	AL117620	80204	2p16.3	Hs.352677	12	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm protein modification process ubiquitin-dependent protein catabolic process zinc ion binding histone-arginine N-methyltransferase activity protein ubiquitination peptidyl-arginine C-methyltransferase activity metal ion binding
217976_s_at	-0.331	7.682	-2.477	2.543e-02	0.244	-3.569	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	3	-32542470	NM_016141	51143	3p22.3	Hs.529495	11	nucleotide binding motor activity ATP binding microtubule dynein complex
216320_x_at	0.228	6.099	2.477	2.545e-02	0.244	-3.569	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	3	-49696384	U37055	4485	3p21	Hs.349110 Hs.512587	31	catalytic activity serine-type endopeptidase activity calcium ion binding extracellular region proteolysis blood coagulation biological_process
217954_s_at	-0.431	7.357	-2.476	2.549e-02	0.244	-3.571	PHF3	PHD finger protein 3	6	64414389	NM_015153	23469	6q12	Hs.348921	13	molecular_function protein binding cellular_component nucleus transcription multicellular organismal development zinc ion binding metal ion binding
210149_s_at	0.232	11.939	2.476	2.550e-02	0.244	-3.571	ATP5H	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d	17	-70546549	AF061735	10476	17q25	Hs.514465	13	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
234803_at	-0.247	2.976	-2.476	2.550e-02	0.244	-3.571	CSTL1	cystatin-like 1	20	23368321	AL096677	128817	20p11.21	Hs.352134	8	cysteine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity
215299_x_at	0.497	7.087	2.476	2.552e-02	0.244	-3.572	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	16	-28524418, -28524418, -28524416	U37025	6817	16p12.1	Hs.567342	134	aryl sulfotransferase activity cytoplasm catecholamine metabolic process lipid metabolic process steroid metabolic process amine metabolic process transferase activity	Sulfur metabolism
220757_s_at	-0.296	6.926	-2.476	2.552e-02	0.244	-3.572	UBXN6	UBX domain protein 6	19	-4396260	NM_025241	80700	19p13	Hs.435255 Hs.661664	6	molecular_function protein binding cellular_component nucleus cytoplasm centrosome biological_process modification-dependent protein catabolic process
243790_at	0.316	5.098	2.476	2.552e-02	0.244	-3.572	ZNF585A	zinc finger protein 585A	19	-42332840, -42332840	AA203136	199704	19q13.12	Hs.390568 Hs.659236	3	nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209783_at	-0.182	5.660	-2.476	2.552e-02	0.244	-3.572	DBP	D site of albumin promoter (albumin D-box) binding protein	19	-53825628	D28468	1628	19q13.3	Hs.414480 Hs.528006	35	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter regulation of cell proliferation sequence-specific DNA binding protein dimerization activity rhythmic process
203558_at	0.208	6.030	2.475	2.554e-02	0.244	-3.573	CUL7	cullin 7	6	-43113332	NM_014780	9820	6p21.1	Hs.520136	17	vasculogenesis protein binding anaphase-promoting complex cytoplasm proteolysis ubiquitin-dependent protein catabolic process regulation of mitotic metaphase/anaphase transition cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
1563462_at	-1.004	3.885	-2.475	2.556e-02	0.244	-3.573	LOC285419	hypothetical LOC285419	4	124793389, 124914868	AL833449	285419	4q28.1	Hs.535763	1
210837_s_at	-0.275	2.675	-2.475	2.556e-02	0.244	-3.573	PDE4D	phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)	5	-58300622, -58300622	AF012074	5144	5q12	Hs.117545	89	3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding	Purine metabolism
223325_at	-0.207	6.489	-2.475	2.557e-02	0.244	-3.574	TXNDC11	thioredoxin domain containing 11	16	-11680443	AF131780	51061	16p13.13	Hs.313847	7	endoplasmic reticulum membrane integral to membrane cell redox homeostasis
226987_at	0.195	5.537	2.475	2.557e-02	0.244	-3.574	RBM15B	RNA binding motif protein 15B	3	51403770	W68720	29890	3p21.2	Hs.118738	6	nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus mRNA processing nucleocytoplasmic transport RNA splicing negative regulation of transcription interspecies interaction between organisms
227971_at	0.331	2.867	2.475	2.558e-02	0.244	-3.574	NRK	Nik related kinase	X	104953191	AI653107	203447	Xq22.3	Hs.209527	9	nucleotide binding transcription factor activity protein serine/threonine kinase activity small GTPase regulator activity ATP binding protein amino acid phosphorylation transferase activity regulation of transcription
218603_at	-0.386	7.834	-2.474	2.559e-02	0.244	-3.574	HECA	headcase homolog (Drosophila)	6	139497941	NM_016217	51696	6q23-q24	Hs.197644	6	molecular_function cellular_component multicellular organismal development respiratory tube development
224897_at	-0.316	8.752	-2.474	2.559e-02	0.244	-3.574	WDR26	WD repeat domain 26	1	-222639467	BF510490	80232	1q42.11-q42.12	Hs.497873	8	cytoplasm
229510_at	0.214	3.526	2.474	2.559e-02	0.244	-3.574	MS4A14	membrane-spanning 4-domains, subfamily A, member 14	11	59920062	AL044520	84689	11q12.2	Hs.709736	3	receptor activity signal transduction membrane integral to membrane
208806_at	0.234	6.140	2.474	2.560e-02	0.244	-3.575	CHD3	chromodomain helicase DNA binding protein 3	17	7728847, 7732893	BE379542	1107	17p13.1	Hs.25601	36	nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter zinc ion binding chromatin modification NuRD complex hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides metal ion binding
225077_at	-0.349	7.405	-2.473	2.563e-02	0.244	-3.576	CHD2	chromodomain helicase DNA binding protein 2	15	91244554, 91244554	AA890703	1106	15q26	Hs.220864	9	nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter hydrolase activity
204795_at	0.252	5.049	2.473	2.563e-02	0.244	-3.576	PRR3	proline rich 3	6	30632734, 1973311, 1771606	NM_025263	80742	6p21.33	Hs.118354 Hs.651434 Hs.83147	4	nucleic acid binding zinc ion binding metal ion binding
209129_at	0.205	5.783	2.473	2.563e-02	0.244	-3.576	TRIP6	thyroid hormone receptor interactor 6	7	100302885	AF000974	7205	7q22	Hs.534360	29	interleukin-1 receptor binding focal adhesion zinc ion binding release of cytoplasmic sequestered NF-kappaB kinase binding positive regulation of cell migration identical protein binding interleukin-1 receptor complex metal ion binding thyroid hormone receptor binding focal adhesion formation
218291_at	0.318	7.666	2.473	2.566e-02	0.244	-3.577	ROBLD3	roadblock domain containing 3	1	154291140	NM_014017	28956	1q22	Hs.632483	5	lysosome endosome membrane
225086_at	-0.270	7.742	-2.473	2.566e-02	0.244	-3.577	FAM98B	family with sequence similarity 98, member B	15	36533619, 36533619	BF679966	283742	15q14	Hs.6799	5	protein binding
230194_at	-0.311	7.658	-2.473	2.566e-02	0.244	-3.577	LRPPRC	leucine-rich PPR-motif containing	2	-43966866	AI341076	10128	2p21	Hs.368084	15	condensed nuclear chromosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus nuclear inner membrane nuclear outer membrane nucleoplasm cytoplasm mitochondrion cytoskeleton transport microtubule binding membrane mitochondrial nucleoid regulation of transcription mitochondrion transport along microtubule perinuclear region of cytoplasm beta-tubulin binding actin filament binding mRNA transport
1552846_s_at	0.223	5.805	2.473	2.566e-02	0.244	-3.577	RAB42	RAB42, member RAS oncogene family	1	28791298	NM_152304	115273	1p35.3	Hs.652321	3	nucleotide binding GTP binding small GTPase mediated signal transduction membrane
239218_at	0.339	3.355	2.473	2.567e-02	0.245	-3.577	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	7	-31795771	AI800515	5137	7p14.3	Hs.655694	10	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity	Purine metabolism Calcium signaling pathway Olfactory transduction
220941_s_at	0.318	3.593	2.472	2.569e-02	0.245	-3.578	C21orf91	chromosome 21 open reading frame 91	21	-18083154	NM_017447	54149	21q21.1	Hs.293811	8
1562740_at	0.245	2.424	2.472	2.570e-02	0.245	-3.578	LOC285224	hypothetical protein LOC285224	3		AK097457	285224	3q21.3	Hs.683815	1
204162_at	0.325	3.030	2.472	2.571e-02	0.245	-3.578	NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	18	2561509	NM_006101	10403	18p11.32	Hs.414407	35	mitotic sister chromatid segregation condensed chromosome kinetochore protein binding nucleus cell cycle spindle organization phosphoinositide-mediated signaling cell division
204613_at	0.374	5.818	2.472	2.571e-02	0.245	-3.578	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	16	80370430	NM_002661	5336	16q24.1	Hs.413111	63	follicular B cell differentiation phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding plasma membrane intracellular signaling cascade phospholipid catabolic process regulation of gene expression lipid catabolic process hydrolase activity activation of store-operated calcium channel activity response to lipopolysaccharide inositol trisphosphate biosynthetic process negative regulation of programmed cell death T cell receptor signaling pathway	Inositol phosphate metabolism Metabolic pathways ErbB signaling pathway Calcium signaling pathway Phosphatidylinositol signaling system VEGF signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Glioma Non-small cell lung cancer
209833_at	0.225	7.178	2.472	2.572e-02	0.245	-3.579	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	12	92595281	U79115	8738	12q21.33-q23.1	Hs.38533 Hs.591016	19	protease binding cysteine-type endopeptidase activity intracellular proteolysis induction of apoptosis signal transduction induction of apoptosis via death domain receptors protein binding, bridging regulation of apoptosis death domain binding
230258_at	0.404	3.944	2.472	2.573e-02	0.245	-3.579	GLIS3	GLIS family zinc finger 3	9	-3814127, -3814127	AI277316	169792	9p24.2	Hs.162125 Hs.644570	8	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular zinc ion binding nuclear part regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
238724_at	-1.003	5.963	-2.471	2.574e-02	0.245	-3.580	BPGM	2,3-bisphosphoglycerate mutase	7	133982070	R63824	669	7q31-q34	Hs.198365 Hs.719267	20	bisphosphoglycerate mutase activity 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity phosphoglycerate mutase activity carbohydrate metabolic process glycolysis respiratory gaseous exchange metabolic process hydrolase activity isomerase activity erythrocyte development	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Metabolic pathways
210053_at	-0.390	4.967	-2.471	2.575e-02	0.245	-3.580	TAF5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	10	105117713	AW138827	6877	10q24-q25.2	Hs.96103	37	transcription factor activity transcription factor activity histone acetyltransferase activity nucleus nucleoplasm transcription factor TFIID complex nucleolus cytoplasm cytoskeleton transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter promoter binding chromatin modification transcription initiation factor activity transcription factor TFTC complex interspecies interaction between organisms regulation of transcription protein dimerization activity	Basal transcription factors
226246_at	0.300	5.467	2.471	2.575e-02	0.245	-3.580	KCTD1	potassium channel tetramerisation domain containing 1	18	-22288871, -22288871, -22288871	AA115278	284252	18q11.2	Hs.526630	7	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
1564536_at	0.304	7.078	2.471	2.575e-02	0.245	-3.580	ASB10	ankyrin repeat and SOCS box-containing 10	7	-150503717, -150503717	AK055536	136371	7q36.1	Hs.647081	6	intracellular signaling cascade modification-dependent protein catabolic process
1569450_at	-0.275	2.680	-2.471	2.576e-02	0.245	-3.580	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	7	116289798	BC015963	830	7q31.2-q31.3	Hs.446123	14	actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping
229796_at	-0.412	8.063	-2.471	2.577e-02	0.245	-3.581	SIX4	SIX homeobox 4	14	-60246008	AI554514	51804	14q23	Hs.690393 Hs.97849	9	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anatomical structure morphogenesis sequence-specific DNA binding
241842_x_at	0.222	4.339	2.471	2.577e-02	0.245	-3.581	C19orf45	chromosome 19 open reading frame 45	19	7468444	AW340486	374877	19p13.2	Hs.631862	3
244654_at	0.293	3.979	2.471	2.578e-02	0.245	-3.581	MYO1G	myosin IG	7	-44968784	BE646398	64005	7p13-p11.2	Hs.37617	8	nucleotide binding motor activity actin binding calmodulin binding ATP binding myosin complex
215505_s_at	-0.491	5.422	-2.471	2.578e-02	0.245	-3.581	STRN3	striatin, calmodulin binding protein 3	14	-30432755	AF243424	29966	14q13-q21	Hs.21016 Hs.401843	13	calmodulin binding membrane fraction nucleus cytoplasm cytosol cell cycle membrane
225686_at	0.325	4.104	2.470	2.581e-02	0.245	-3.582	SKA2	spindle and kinetochore associated complex subunit 2	17	-54542089	BE048371	348235	17q22	Hs.463607	7	mitotic anaphase outer kinetochore of condensed chromosome protein binding spindle microtubule cell cycle chromosome segregation microtubule binding regulation of microtubule polymerization or depolymerization cell division
228634_s_at	-0.539	6.543	-2.470	2.583e-02	0.245	-3.583	CSDA	cold shock domain protein A	12	-10742944	BF195718	8531	12p13.1	Hs.221889	20	negative regulation of transcription from RNA polymerase II promoter double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity transcription corepressor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to cold	Tight junction
223666_at	-0.300	5.137	-2.468	2.589e-02	0.246	-3.585	SNX5	sorting nexin 5	20	-17870243, -17870243	BC002724	27131	20p11	Hs.316890	14	protein binding cell communication protein transport phosphoinositide binding
243438_at	0.211	5.279	2.468	2.590e-02	0.246	-3.585	PDE7B	phosphodiesterase 7B	6	136214526	BE968570	27115	6q23-q24	Hs.719318	6	3',5'-cyclic-AMP phosphodiesterase activity signal transduction synaptic transmission hydrolase activity	Purine metabolism
1561660_at	-0.288	2.591	-2.468	2.590e-02	0.246	-3.585	MCART6	mitochondrial carrier triple repeat 6	X	-103230553	AL833609	401612	Xq22.2	Hs.660022	1	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
213838_at	-0.290	7.173	-2.468	2.591e-02	0.246	-3.585	NOL7	nucleolar protein 7, 27kDa	6	13723537	AA191426	51406	6p23	Hs.306242	9	nucleus nucleolus
242835_s_at	-0.323	5.308	-2.468	2.591e-02	0.246	-3.585	LOC728730	hypothetical LOC728730	2		AW772084	728730	2p22.1
218157_x_at	0.283	6.224	2.468	2.591e-02	0.246	-3.586	CDC42SE1	CDC42 small effector 1	1	-149290070	NM_020239	56882	1q21.3	Hs.22065	4	GTPase inhibitor activity protein binding cytoplasm cytoskeleton plasma membrane phagocytosis signal transduction regulation of cell shape
204233_s_at	0.237	5.092	2.468	2.593e-02	0.246	-3.586	CHKA	choline kinase alpha	11	-67576901	AI991328	1119	11q13.2	Hs.77221	21	nucleotide binding choline kinase activity cholinesterase activity signal transducer activity ATP binding cytoplasm lipid metabolic process phosphatidylcholine biosynthetic process lipid transport transferase activity protein homodimerization activity	Glycerophospholipid metabolism Metabolic pathways
211528_x_at	0.388	9.241	2.468	2.593e-02	0.246	-3.586	HLA-G	major histocompatibility complex, class I, G	6	29902734, 1247153, 1049287	M90685	3135	6p21.3	Hs.512152	316	antigen processing and presentation of peptide antigen via MHC class I immune response cellular defense response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
233916_at	0.298	3.388	2.467	2.597e-02	0.246	-3.587	KIAA1486	KIAA1486	2	225973845	AB040919	57624	2q36.3	Hs.224409	4
213154_s_at	-0.352	7.691	-2.467	2.599e-02	0.246	-3.588	BICD2	bicaudal D homolog 2 (Drosophila)	9	-94513465	AI934125	23299	9q22.31	Hs.436939	15	protein binding cytoplasm Golgi apparatus cytoskeleton transport microtubule-based movement
230209_at	-0.669	5.252	-2.466	2.601e-02	0.246	-3.589	ZXDC	ZXD family zinc finger C	3	-127652648, -127639133	AW194655	79364	3q21.3	Hs.440049 Hs.711046	8	nucleic acid binding transcription factor activity intracellular nucleus zinc ion binding transcription activator activity LRR domain binding identical protein binding positive regulation of transcription metal ion binding C2H2 zinc finger domain binding
223294_at	-0.342	7.370	-2.466	2.602e-02	0.246	-3.589	CXorf26	chromosome X open reading frame 26	X	75309172	BC001220	51260	Xq13.3	Hs.370100	6	molecular_function cellular_component biological_process
210005_at	0.341	4.198	2.466	2.603e-02	0.246	-3.590	GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	21	-33818186, -33798108, -33798108, -33798108	D32051	2618	21q22.1 21q22.11	Hs.473648	23	nucleotide binding phosphoribosylamine-glycine ligase activity phosphoribosylamine-glycine ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylglycinamide formyltransferase activity protein binding ATP binding cytoplasm cytosol purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process methyltransferase activity biosynthetic process purine base biosynthetic process transferase activity ligase activity manganese ion binding metal ion binding	Purine metabolism One carbon pool by folate Metabolic pathways
208158_s_at	-0.250	10.171	-2.465	2.604e-02	0.246	-3.590	OSBPL1A	oxysterol binding protein-like 1A	18	-19996008, -19996008	NM_018030	114876	18q11.1	Hs.370725	12	phospholipid binding intracellular lipid transport steroid metabolic process cholesterol metabolic process vesicle-mediated transport
205101_at	0.330	4.695	2.465	2.604e-02	0.246	-3.590	CIITA	class II, major histocompatibility complex, transactivator	16	10878555	NM_000246	4261	16p13	Hs.701991	112	nucleotide binding DNA binding RNA polymerase II transcription factor activity transcription coactivator activity ATP binding nucleus immune response protein C-terminus binding negative regulation of specific transcription from RNA polymerase II promoter promoter binding transcription repressor activity protein complex binding negative regulation of collagen biosynthetic process transcription activator binding response to interferon-gamma ubiquitin binding positive regulation of MHC class II biosynthetic process regulation of transcription positive regulation of transcription from RNA polymerase II promoter response to antibiotic	Antigen processing and presentation Primary immunodeficiency
207312_at	-0.764	7.698	-2.465	2.605e-02	0.246	-3.590	PHKG1	phosphorylase kinase, gamma 1 (muscle)	7	-56116168	NM_006213	5260	7p11.2	Hs.715728	23	nucleotide binding protein serine/threonine kinase activity phosphorylase kinase activity calmodulin binding ATP binding phosphorylase kinase complex carbohydrate metabolic process glycogen biosynthetic process protein amino acid phosphorylation transferase activity	Calcium signaling pathway Insulin signaling pathway
226225_at	0.669	6.595	2.465	2.606e-02	0.246	-3.591	MCC	mutated in colorectal cancers	5	-112385694, -112385694	BE967311	4163	5q21	Hs.593171	18	receptor activity protein binding signal transduction
209849_s_at	0.276	7.761	2.465	2.606e-02	0.246	-3.591	RAD51C	RAD51 homolog C (S. cerevisiae)	17	54124961, 54124961	AF029669	5889	17q22-q23	Hs.412587	33	nucleotide binding DNA binding ATP binding nucleus DNA repair response to DNA damage stimulus female meiosis sister chromatid cohesion reciprocal meiotic recombination male meiosis I spermatogenesis DNA-dependent ATPase activity crossover junction endodeoxyribonuclease activity nucleoside-triphosphatase activity	Homologous recombination
202113_s_at	-0.403	7.757	-2.464	2.610e-02	0.247	-3.592	SNX2	sorting nexin 2	5	122138648	AF043453	6643	5q23	Hs.713554	20	protein binding cytoplasm intracellular protein transport endocytosis cell communication protein transporter activity phosphoinositide binding
221339_at	-0.218	3.010	-2.464	2.610e-02	0.247	-3.592	OR10C1	olfactory receptor, family 10, subfamily C, member 1	6	29515771, 863077, 665027	NM_013941	442194	6p22.1	Hs.631997	4	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
32723_at	0.392	6.344	2.464	2.612e-02	0.247	-3.593	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	20	54400833, 54400980, 54401113	L02547	1477	20q13.2	Hs.172865	19	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA polyadenylation mRNA cleavage
221774_x_at	-0.207	5.992	-2.464	2.613e-02	0.247	-3.593	FAM48A	family with sequence similarity 48, member A	13	-36481450	AW003334	55578	13q13.3	Hs.435815	14	protein binding multicellular organismal development gastrulation
229044_at	0.232	5.806	2.463	2.615e-02	0.247	-3.594	NUDT17	nudix (nucleoside diphosphate linked moiety X)-type motif 17	1	-144297851	AA284522	200035	1q21.1	Hs.585066	4	magnesium ion binding mitochondrion hydrolase activity manganese ion binding
208662_s_at	-0.373	8.410	-2.463	2.618e-02	0.247	-3.595	TTC3	tetratricopeptide repeat domain 3	21	37367440, 37377116	AI885338	7267	21q22.2	Hs.368214	9	protein binding cellular_component vacuole biological_process zinc ion binding negative regulation of cell morphogenesis involved in differentiation negative regulation of neuron differentiation metal ion binding response to protein stimulus
210746_s_at	0.163	3.885	2.463	2.618e-02	0.247	-3.595	EPB42	erythrocyte membrane protein band 4.2	15	-41276717	M30646	2038	15q15-q21	Hs.368642	34	cell morphogenesis protein-glutamine gamma-glutamyltransferase activity structural constituent of cytoskeleton protein binding ATP binding cytoplasm plasma membrane regulation of cell shape peptide cross-linking hemoglobin metabolic process cortical cytoskeleton erythrocyte maturation spleen development ion homeostasis iron ion homeostasis
225649_s_at	-0.621	6.829	-2.462	2.620e-02	0.247	-3.595	STK35	serine/threonine kinase 35	20	2031518	AA001414	140901	20p13	Hs.100057	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity
226942_at	-0.341	5.788	-2.462	2.620e-02	0.247	-3.595	PHF20L1	PHD finger protein 20-like 1	8	133856785, 133856785, 133856785	AI742668	51105	8q24.22	Hs.304362	4	nucleic acid binding protein binding zinc ion binding metal ion binding
219350_s_at	0.203	8.408	2.462	2.620e-02	0.247	-3.595	DIABLO	diablo homolog (Drosophila)	12	-121258162	NM_019887	56616	12q24.31	Hs.169611	91	protein binding mitochondrion cytosol induction of apoptosis induction of apoptosis via death domain receptors activation of caspase activity by cytochrome c
212895_s_at	0.240	6.877	2.462	2.621e-02	0.247	-3.596	ABR	active BCR-related gene	17	-853509, -853508, -853508	AL527773	29	17p13.3	Hs.159306	11	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular small GTPase mediated signal transduction regulation of Rho protein signal transduction
208926_at	-0.282	6.480	-2.462	2.621e-02	0.247	-3.596	NEU1	sialidase 1 (lysosomal sialidase)	6	-31934807, -3273082, -3074566	U84246	4758	6p21.3	Hs.520037	41	exo-alpha-sialidase activity protein binding plasma membrane metabolic process hydrolase activity, acting on glycosyl bonds cytoplasmic vesicle lysosomal lumen	Other glycan degradation Sphingolipid metabolism Lysosome
227428_at	-0.303	6.929	-2.462	2.624e-02	0.247	-3.597	GABPA	GA binding protein transcription factor, alpha subunit 60kDa	21	26029199	BE876628	2551	21q21-q22.1 21q21.3	Hs.246310 Hs.473470	34	negative regulation of transcription from RNA polymerase II promoter in utero embryonic development transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nucleolus sequence-specific DNA binding
202990_at	0.353	4.741	2.462	2.624e-02	0.247	-3.597	PYGL	phosphorylase, glycogen, liver	14	-50441685	NM_002863	5836	14q21-q22	Hs.282417	19	nucleotide binding purine binding ATP binding glucose binding soluble fraction carbohydrate metabolic process glycogen metabolic process drug binding glycogen phosphorylase activity AMP binding transferase activity, transferring glycosyl groups vitamin binding pyridoxal phosphate binding bile acid binding glucose homeostasis protein homodimerization activity	Starch and sucrose metabolism Insulin signaling pathway
243316_x_at	-0.230	2.638	-2.462	2.624e-02	0.247	-3.597	VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)	10	70553913	AA004710	9559	10q21.1	Hs.499925	17	protein binding cytoplasm endosome cytosol vacuolar transport protein transporter activity protein transport membrane retromer complex retrograde transport, endosome to Golgi
230737_s_at	0.214	4.357	2.462	2.624e-02	0.247	-3.597	LOC387647	patched domain containing 3 pseudogene	10	29738506	AW118878	387647	10p11.23	Hs.719271	2
212383_at	-0.245	7.523	-2.461	2.625e-02	0.247	-3.597	ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1	17	37864387	AL096733	535	17q21	Hs.463074	21	protein binding cytoplasm plasma membrane ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport integral to membrane cytoplasmic vesicle proton-transporting two-sector ATPase complex, proton-transporting domain melanosome ATPase binding	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
210615_at	0.198	4.033	2.461	2.625e-02	0.247	-3.597	NRP1	neuropilin 1	10	-33526552, -33506424	AF280547	8829	10p12	Hs.131704 Hs.714624	91	angiogenesis receptor activity vascular endothelial growth factor receptor activity protein binding extracellular region plasma membrane cell adhesion signal transduction cell-cell signaling multicellular organismal development nervous system development axon guidance positive regulation of cell proliferation organ morphogenesis integral to membrane cell differentiation	Axon guidance
225556_at	0.220	7.459	2.461	2.626e-02	0.247	-3.597	VMA21	VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)	X	150316362	BG290058	203547	Xq28	Hs.58633	10	lysosome endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane COPII vesicle coat cytoplasmic vesicle vacuolar proton-transporting V-type ATPase complex assembly
231980_at	-0.200	2.320	-2.461	2.626e-02	0.247	-3.597	DOK6	docking protein 6	18	65219270	AL120332	220164	18q22.2	Hs.278285	4	insulin receptor binding
201230_s_at	-0.375	7.925	-2.461	2.627e-02	0.247	-3.598	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	NM_006321	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
208750_s_at	-0.545	8.765	-2.461	2.628e-02	0.247	-3.598	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AA580004	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
40465_at	-0.316	6.500	-2.461	2.628e-02	0.247	-3.598	DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	12	-47509805	AF026402	9416	12q13.12	Hs.130098	13	nucleotide binding cis assembly of pre-catalytic spliceosome nuclear mRNA splicing, via spliceosome nucleic acid binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus spliceosomal complex U5 snRNP RNA splicing hydrolase activity RNA splicing factor activity, transesterification mechanism
221884_at	0.326	5.524	2.461	2.629e-02	0.247	-3.598	MECOM	MDS1 and EVI1 complex locus	3	-170283980, -170283980, -170283980, -170283980	BE466525	2122	3q24-q28	Hs.659873 Hs.719216	46	molecular_function DNA binding transcription factor activity protein binding intracellular nucleus multicellular organismal development biological_process zinc ion binding metal ion binding	MAPK signaling pathway Pathways in cancer Chronic myeloid leukemia
205891_at	0.256	4.176	2.460	2.630e-02	0.247	-3.599	ADORA2B	adenosine A2b receptor	17	15788955	NM_000676	136	17p12-p11.2	Hs.167046	38	activation of MAPK activity adenosine receptor activity, G-protein coupled positive regulation of chronic inflammatory response to non-antigenic stimulus receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane cellular defense response signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway JNK cascade excretion positive regulation vascular endothelial growth factor production positive regulation of cAMP biosynthetic process positive regulation of cGMP biosynthetic process positive regulation of guanylate cyclase activity cellular response to extracellular stimulus positive regulation of chemokine production positive regulation of interleukin-6 production positive regulation of mast cell degranulation regulation of angiogenesis relaxation of vascular smooth muscle	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction
223551_at	-0.617	4.326	-2.460	2.630e-02	0.247	-3.599	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta	6	122834760, 122973075	AF225513	5570	6q22.31	Hs.719228	10	protein kinase inhibitor activity cAMP-dependent protein kinase inhibitor activity negative regulation of protein kinase activity
218050_at	-0.322	7.335	-2.460	2.631e-02	0.247	-3.599	UFM1	ubiquitin-fold modifier 1	13	37821941	NM_016617	51569	13q13.3	Hs.643655 Hs.719178	11	protein binding nucleus cytoplasm modification-dependent protein catabolic process
206468_s_at	-0.207	5.991	-2.460	2.631e-02	0.247	-3.599	METTL13	methyltransferase like 13	1	170017383	NM_015935	51603	1q24-q25.3	Hs.494705	11	metabolic process methyltransferase activity transferase activity
229245_at	0.353	4.256	2.460	2.632e-02	0.247	-3.599	PLEKHA6	pleckstrin homology domain containing, family A member 6	1	-202454603	AA535361	22874	1q32.1	Hs.253146	9
204136_at	0.260	6.388	2.460	2.632e-02	0.247	-3.599	COL7A1	collagen, type VII, alpha 1	3	-48576509	NM_000094	1294	3p21.1	Hs.476218	93	serine-type endopeptidase inhibitor activity protein binding extracellular region collagen type VII basement membrane cell adhesion epidermis development peptidase inhibitor activity
1559139_at	0.281	4.713	2.460	2.633e-02	0.247	-3.600	NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	1	-869445	BC009786	26155	1p36.33	Hs.405987	23	protein binding nucleus nucleolus
1569354_at	0.217	3.689	2.460	2.633e-02	0.247	-3.600	NSUN6	NOL1/NOP2/Sun domain family, member 6	10	-18874269	BC033534	221078	10p12.31	Hs.396175	4	RNA binding methyltransferase activity transferase activity
208371_s_at	0.214	7.767	2.460	2.634e-02	0.247	-3.600	RING1	ring finger protein 1	6	33284263, 4556442, 4362459	NM_002931	6015	6p21.3	Hs.631989	26	ubiquitin ligase complex sex chromatin chromatin binding ubiquitin-protein ligase activity retinoid-X receptor activity protein binding nucleus nucleolus cytoplasm zinc ion binding anterior/posterior pattern formation transcription repressor activity chromatin modification histone ubiquitination nuclear speck ligase activity modification-dependent protein catabolic process thyroid hormone receptor coactivator activity PcG protein complex vitamin D receptor binding retinoic acid receptor binding regulation of transcription metal ion binding thyroid hormone receptor binding protein heterodimerization activity camera-type eye morphogenesis
212151_at	-0.342	8.826	-2.460	2.634e-02	0.247	-3.600	PBX1	pre-B-cell leukemia homeobox 1	1	162795425	BF967998	5087	1q23	Hs.557097	56	transcription factor activity protein binding nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent C21-steroid hormone biosynthetic process sex determination cell differentiation sequence-specific DNA binding
218158_s_at	-0.414	7.947	-2.460	2.635e-02	0.247	-3.600	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	3	57236804	NM_012096	26060	3p21.1-p14.3	Hs.476415	23	protein binding nucleus cytoplasm endosome microsome cytosol cell cycle signal transduction cell proliferation insulin receptor signaling pathway endosome membrane vesicle membrane membrane NuRD complex protein kinase B binding regulation of glucose import regulation of establishment of protein localization	Pathways in cancer Colorectal cancer
1558703_at	0.299	5.409	2.459	2.636e-02	0.247	-3.601	SLC46A1	solute carrier family 46 (folate transporter), member 1	17	-23745787	AL832613	113235	17q11.2	Hs.446689	22	folic acid binding cytoplasm plasma membrane transport folic acid transporter activity folic acid transport integral to membrane apical plasma membrane
229906_at	0.291	4.434	2.459	2.637e-02	0.247	-3.601	ARMC7	armadillo repeat containing 7	17	70617676	BF194773	79637	17q25.1	Hs.413047	4	binding
225826_at	0.227	7.439	2.459	2.638e-02	0.247	-3.602	MMAB	methylmalonic aciduria (cobalamin deficiency) cblB type	12	-108475903	AV702487	326625	12q24	Hs.12106	16	nucleotide binding ATP binding mitochondrion cob(I)yrinic acid a,c-diamide adenosyltransferase activity cobalamin biosynthetic process transferase activity	Porphyrin and chlorophyll metabolism Metabolic pathways
218369_s_at	0.235	3.468	2.459	2.639e-02	0.247	-3.602	EXOSC1	exosome component 1	10	-99185655	NM_016046	51013	10q24	Hs.632089	14	exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus rRNA processing hydrolase activity	RNA degradation
223884_at	0.277	5.496	2.459	2.640e-02	0.247	-3.602	OPTC	opticin	1	201729893	AF161702	26254	1q32.1	Hs.632468	14	extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix
205024_s_at	-0.185	4.407	-2.458	2.640e-02	0.247	-3.602	RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	15	38774650	NM_002875	5888	15q15.1	Hs.631709	241	recombinase activity nucleotide binding double-strand break repair via homologous recombination condensed nuclear chromosome damaged DNA binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding ATP binding nucleus nucleus nucleoplasm DNA unwinding during replication DNA repair mitotic recombination response to DNA damage stimulus meiosis reciprocal meiotic recombination protein C-terminus binding PML body ATPase activity identical protein binding single-stranded DNA-dependent ATPase activity positive regulation of DNA ligation protein homooligomerization	Homologous recombination Pathways in cancer Pancreatic cancer
218461_at	-0.386	8.672	-2.458	2.642e-02	0.247	-3.603	GPN3	GPN-loop GTPase 3	12	-109374673	NM_016301	51184	12q24.11	Hs.634680	9	nucleotide binding GTP binding protein complex
239359_at	-0.239	4.505	-2.458	2.643e-02	0.247	-3.603	MARCH11	membrane-associated ring finger (C3HC4) 11	5	-16120473	AA383208	441061	5p15.1	Hs.662216	2	zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process cytoplasmic vesicle metal ion binding
215598_at	0.179	3.424	2.458	2.645e-02	0.248	-3.604	TTC12	tetratricopeptide repeat domain 12	11	112690460	AK027161	54970	11q23.2	Hs.288772	11	binding
235692_at	0.406	5.955	2.457	2.646e-02	0.248	-3.604	SH3KBP1	SH3-domain kinase binding protein 1	X	-19462003, -19462003	AW024527	30011	Xp22.1-p21.3	Hs.719268	58	molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse	Endocytosis
234026_at	0.241	5.911	2.457	2.646e-02	0.248	-3.604	EML2	echinoderm microtubule associated protein like 2	19	-50804497	AK024984	24139	19q13.32	Hs.24178	8	serine-type endopeptidase activity protein binding cytoplasm microtubule microtubule associated complex proteolysis visual perception sensory perception of sound intracellular membrane-bounded organelle
212553_at	-0.208	7.955	-2.457	2.647e-02	0.248	-3.605	RPRD2	regulation of nuclear pre-mRNA domain containing 2	1	148603613	AK026120	23248	1q21.3	Hs.213666	9	protein binding
226371_at	-0.289	5.291	-2.457	2.650e-02	0.248	-3.606	KDM5A	lysine (K)-specific demethylase 5A	12	-259483	AI672662	5927	12p11	Hs.76272	25	transcription factor activity iron ion binding protein binding intracellular nucleus nucleolus cytoplasm transcription from RNA polymerase II promoter multicellular organismal development zinc ion binding oxidoreductase activity transcription activator activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cyclin-dependent protein kinase activating kinase holoenzyme complex positive regulation of transcription metal ion binding oxidation reduction
201621_at	0.302	6.768	2.456	2.651e-02	0.248	-3.606	NBL1	neuroblastoma, suppression of tumorigenicity 1	1	19842312, 19843394	NM_005380	4681	1p36.13	Hs.654502	18	extracellular region
201506_at	0.411	6.943	2.456	2.652e-02	0.248	-3.606	TGFBI	transforming growth factor, beta-induced, 68kDa	5	135392482	NM_000358	7045	5q31	Hs.369397 Hs.645734	127	integrin binding protein binding extracellular region proteinaceous extracellular matrix extracellular space negative regulation of cell adhesion visual perception cell proliferation response to stimulus
211221_at	-0.245	4.365	-2.456	2.653e-02	0.248	-3.607	TADA3L	transcriptional adaptor 3 (NGG1 homolog, yeast)-like	3	-9799811, -9796653	AL117487	10474	3p25.3	Hs.386390	29	transcription factor activity transcription coactivator activity histone acetyltransferase activity protein binding intracellular nucleus regulation of transcription from RNA polymerase II promoter STAGA complex transcription factor TFTC complex histone H3 acetylation regulation of transcription
1559635_at	0.223	4.594	2.456	2.655e-02	0.248	-3.607	CASC4	cancer susceptibility candidate 4	15	42368220	AK098265	113201	15q15.3	Hs.512867	6	membrane integral to membrane
218892_at	0.258	5.001	2.456	2.655e-02	0.248	-3.607	DCHS1	dachsous 1 (Drosophila)	11	-6599133	NM_024542	8642	11p15.4	Hs.199850	3	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane calcium-dependent cell-cell adhesion
1553510_s_at	-0.247	7.313	-2.455	2.657e-02	0.248	-3.608	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	2	219141921	NM_005444	9125	2q35	Hs.148767	6	protein binding nucleus sex differentiation cytokine-mediated signaling pathway regulation of transcription	RNA degradation
210555_s_at	-0.421	6.806	-2.455	2.657e-02	0.248	-3.608	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	16	66676875, 66676875	U85430	4775	16q22.2	Hs.632209	32	transcription factor activity nucleus cytoplasm regulation of transcription from RNA polymerase II promoter inflammatory response	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
1555271_a_at	0.239	5.059	2.455	2.658e-02	0.248	-3.608	TERT	telomerase reverse transcriptase	5	-1306286	AB085628	7015	5p15.33	Hs.492203	518	telomere maintenance chromosome, telomeric region nuclear telomere cap complex DNA binding telomeric template RNA reverse transcriptase activity protein binding nucleus nucleoplasm chromosome telomerase holoenzyme complex anti-apoptosis telomere maintenance via telomerase senescence transferase activity nucleotidyltransferase activity DNA strand elongation telomere formation via telomerase telomeric DNA binding protein homodimerization activity telomeric RNA binding
221495_s_at	-0.239	7.674	-2.455	2.659e-02	0.248	-3.609	TCF25	transcription factor 25 (basic helix-loop-helix)	16	88467494	AF322111	22980	16q24.3	Hs.415342	9	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus heart development regulation of transcription
223189_x_at	-0.312	7.558	-2.455	2.661e-02	0.248	-3.609	MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)	7	104441872	AW082219	55904	7q22.1	Hs.592262	10	neutrophil mediated immunity transcription coactivator activity nucleus DNA methylation cell cycle cell cycle arrest methyltransferase activity zinc ion binding chromatin modification histone methylation nuclear speck transferase activity enzyme binding erythrocyte differentiation response to retinoic acid neutrophil activation histone methyltransferase activity (H3-K4 specific) regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding retinoic acid receptor signaling pathway MLL5-L complex
1563512_at	-0.174	3.279	-2.455	2.661e-02	0.248	-3.609	NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	1	160306204, 160599396	AK024942	9722	1q23.3	Hs.655000	41	protein binding PDZ domain binding nitric-oxide synthase binding
212189_s_at	-0.321	7.333	-2.455	2.661e-02	0.248	-3.609	COG4	component of oligomeric golgi complex 4	16	-69071972	AK022874	25839	16q22.1	Hs.208680	11	protein binding Golgi apparatus protein transport membrane Golgi transport complex
231773_at	-0.571	7.221	-2.454	2.663e-02	0.248	-3.610	ANGPTL1	angiopoietin-like 1	1	-177085292	BF002046	9068	1q25.2	Hs.591474	19	receptor binding extracellular region extracellular space signal transduction
213866_at	0.294	6.086	2.454	2.663e-02	0.248	-3.610	SAMD14	sterile alpha motif domain containing 14	17	-45545033	AL134453	201191	17q21.33	Hs.567769	6
229912_at	0.287	3.693	2.454	2.664e-02	0.248	-3.610	SDK1	sidekick homolog 1, cell adhesion molecule (chicken)	7	3307605, 4135842	AL042166	221935	7p22.2	Hs.653013	7	protein binding cell adhesion membrane integral to membrane
200928_s_at	-0.212	3.394	-2.454	2.665e-02	0.248	-3.610	RAB14	RAB14, member RAS oncogene family	9	-122980236	AL162081	51552	9q32-q34.11	Hs.371563 Hs.713585	19	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm
233375_at	0.712	6.225	2.454	2.665e-02	0.248	-3.611	EFCAB2	EF-hand calcium binding domain 2	1	243199793, 243199906, 243200253, 243200253	AK001393	84288	1q44	Hs.134857	5	calcium ion binding
229665_at	0.328	6.178	2.454	2.665e-02	0.248	-3.611	CSTF3	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	11	-33119552, -33062705	AI653037	1479	11p13	Hs.44402	15	nuclear mRNA splicing, via spliceosome RNA binding protein binding intracellular nucleus mRNA polyadenylation mRNA cleavage
218790_s_at	0.254	5.262	2.454	2.666e-02	0.248	-3.611	TMLHE	trimethyllysine hydroxylase, epsilon	X	-154372966	NM_018196	55217	Xq28	Hs.133321	12	iron ion binding mitochondrion mitochondrial matrix mitochondrial matrix electron carrier activity oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding carnitine biosynthetic process trimethyllysine dioxygenase activity oxidation reduction	Lysine degradation
200951_s_at	0.235	3.456	2.453	2.666e-02	0.248	-3.611	CCND2	cyclin D2	12	4253162	AW026491	894	12p13	Hs.376071	73	G1/S transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex positive regulation of protein amino acid phosphorylation protein binding nucleus positive regulation of cell proliferation protein kinase binding positive regulation of cyclin-dependent protein kinase activity cell division regulation of cell cycle	Cell cycle p53 signaling pathway Wnt signaling pathway Focal adhesion Jak-STAT signaling pathway
203384_s_at	-0.236	5.872	-2.453	2.668e-02	0.249	-3.612	GOLGA1	golgi autoantigen, golgin subfamily a, 1	9	-126680394	NM_002077	2800	9q33.3	Hs.133469 Hs.59504	11	Golgi apparatus membrane
218068_s_at	-0.344	7.409	-2.453	2.669e-02	0.249	-3.612	ZNF672	zinc finger protein 672	1	247099152	NM_024836	79894	1q44	Hs.702427	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
213352_at	-0.592	6.674	-2.453	2.670e-02	0.249	-3.612	TMCC1	transmembrane and coiled-coil domain family 1	3	-130849324, -130849324	AB018322	23023	3q22.1	Hs.477547 Hs.709936	6	membrane integral to membrane
212074_at	-0.309	9.665	-2.453	2.671e-02	0.249	-3.613	UNC84A	unc-84 homolog A (C. elegans)	7	822777	BE972774	23353	7p22.3	Hs.438072	18	protein binding nucleus integral to nuclear inner membrane cytoplasm membrane integral to membrane nuclear membrane perinuclear region of cytoplasm
1552424_at	0.341	2.866	2.452	2.672e-02	0.249	-3.613	KLHL10	kelch-like 10 (Drosophila)	17	37247568	NM_152467	317719	17q21.2	Hs.127510	6	protein binding cytoplasm
38703_at	-0.273	8.876	-2.452	2.673e-02	0.249	-3.613	DNPEP	aspartyl aminopeptidase	2	-219946423	AF005050	23549	2q35	Hs.258551	8	aminopeptidase activity protein binding cytoplasm vacuole proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding metal ion binding
211029_x_at	0.286	4.014	2.452	2.674e-02	0.249	-3.614	FGF18	fibroblast growth factor 18	5	170779271	BC006245	8817	5q34	Hs.87191	25	angiogenesis intramembranous ossification endochondral ossification chondrocyte development extracellular region extracellular region extracellular space nucleolus signal transduction cell-cell signaling growth factor activity positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis lung development positive regulation of vascular endothelial growth factor receptor signaling pathway	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
1563426_a_at	0.319	4.127	2.452	2.676e-02	0.249	-3.614	LOC644613	hypothetical protein LOC644613	11		BC025792	644613	11q13.1	Hs.604039	1
212878_s_at	-0.343	7.919	-2.451	2.678e-02	0.249	-3.615	KLC1	kinesin light chain 1	14	103165277, 103165277	AA284075	3831	14q32.3	Hs.20107 Hs.657678	31	microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle
206637_at	0.499	5.265	2.451	2.679e-02	0.249	-3.615	P2RY14	purinergic receptor P2Y, G-protein coupled, 14	3	-152412594, -152412594	NM_014879	9934	3q24-q25.1	Hs.2465	27	receptor activity G-protein coupled receptor activity plasma membrane immune response signal transduction G-protein coupled receptor protein signaling pathway integral to membrane purinergic nucleotide receptor activity, G-protein coupled UDP-activated nucleotide receptor activity	Neuroactive ligand-receptor interaction
229427_at	0.199	5.005	2.451	2.680e-02	0.249	-3.616	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	5	-9088137	BF940761	9037	5p15.2	Hs.27621	19	patterning of blood vessels receptor activity cell adhesion cell-cell signaling multicellular organismal development nervous system development axon guidance axon guidance receptor activity membrane integral to membrane cell differentiation	Axon guidance
213351_s_at	-0.480	7.596	-2.451	2.680e-02	0.249	-3.616	TMCC1	transmembrane and coiled-coil domain family 1	3	-130849324, -130849324	AB018322	23023	3q22.1	Hs.477547 Hs.709936	6	membrane integral to membrane
1562436_at	0.222	4.017	2.451	2.681e-02	0.249	-3.616	CARS	cysteinyl-tRNA synthetase	11	-2978734	AK093033	833	11p15.5	Hs.274873	14	tRNA binding tRNA binding nucleotide binding cysteine-tRNA ligase activity protein binding ATP binding cytoplasm translation cysteinyl-tRNA aminoacylation zinc ion binding ligase activity protein homodimerization activity metal ion binding	Aminoacyl-tRNA biosynthesis
210131_x_at	0.259	9.053	2.450	2.682e-02	0.249	-3.616	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	1	159550789	D49737	6391	1q23.3	Hs.444472	27	succinate dehydrogenase activity iron ion binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane tricarboxylic acid cycle transport electron carrier activity membrane integral to membrane electron transport chain respiratory chain complex II metal ion binding	Citrate cycle (TCA cycle) Oxidative phosphorylation Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
212038_s_at	-0.402	11.646	-2.450	2.683e-02	0.249	-3.617	VDAC1	voltage-dependent anion channel 1	5	-133335505	AL515918	7416	5q31	Hs.519320 Hs.709372	73	behavioral fear response protein binding mitochondrion mitochondrial outer membrane mitochondrial inner membrane plasma membrane anion transport apoptosis nerve-nerve synaptic transmission learning voltage-gated anion channel activity voltage-gated anion channel activity mitochondrial nucleoid interspecies interaction between organisms pore complex	Calcium signaling pathway Parkinson's disease Huntington's disease
241859_at	-0.605	5.324	-2.450	2.684e-02	0.249	-3.617	PLCL1	phospholipase C-like 1	2	198377670, 198377777	BF593050	5334	2q33	Hs.153322 Hs.593586	8	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
225099_at	-0.396	7.385	-2.450	2.685e-02	0.249	-3.617	FBXO45	F-box protein 45	3	197780121	AA126446	200933	3q29	Hs.169815	2	modification-dependent protein catabolic process
203030_s_at	0.253	4.774	2.450	2.686e-02	0.249	-3.618	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2	7	-157024510	AF007555	5799	7q36	Hs.490789 Hs.715864 Hs.716042	19	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation membrane hydrolase activity	Type I diabetes mellitus
212837_at	-0.256	7.849	-2.450	2.687e-02	0.249	-3.618	FAM175B	family with sequence similarity 175, member B	10	126480343	D63877	23172	10q26.13	Hs.280695	10	protein binding polyubiquitin binding BRISC complex
218184_at	-0.396	6.485	-2.449	2.689e-02	0.250	-3.619	TULP4	tubby like protein 4	6	158653679	NM_020245	56995	6q25-q26	Hs.486993	7	transcription factor activity protein binding cellular_component cytoplasm regulation of transcription, DNA-dependent intracellular signaling cascade response to nutrient modification-dependent protein catabolic process
220050_at	0.358	4.775	2.449	2.691e-02	0.250	-3.619	C9orf9	chromosome 9 open reading frame 9	9	134744110	NM_018956	11092	9q34	Hs.62595	6
204125_at	-0.453	9.234	-2.449	2.691e-02	0.250	-3.619	NDUFAF1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1	15	-39466842	NM_016013	51103	15q11.2-q21.3	Hs.106529	11	mitochondrion mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone protein complex assembly unfolded protein binding
201847_at	0.411	6.862	2.449	2.692e-02	0.250	-3.619	LIPA	lipase A, lysosomal acid, cholesterol esterase	10	-90963309, -90963305	NM_000235	3988	10q23.2-q23.3	Hs.643030	28	sterol esterase activity lysosome protein amino acid N-linked glycosylation lipid catabolic process hydrolase activity	Steroid biosynthesis Lysosome
207212_at	0.256	4.234	2.448	2.693e-02	0.250	-3.620	SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	5	-526333	NM_004174	6550	5p15.3	Hs.658120	46	regulation of sodium ion transport protein binding cation transport regulation of pH receptor-mediated endocytosis circadian rhythm cell surface antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane apical plasma membrane sodium ion binding brush border membrane response to glucocorticoid stimulus
218377_s_at	-0.355	7.689	-2.448	2.693e-02	0.250	-3.620	RWDD2B	RWD domain containing 2B	21	-29299952	NM_016940	10069	21q22.11	Hs.716643	8	molecular_function cellular_component biological_process
227564_at	0.312	5.560	2.448	2.693e-02	0.250	-3.620	HGSNAT	heparan-alpha-glucosaminide N-acetyltransferase	8	43114748	BF433005	138050	8p11.1	Hs.600384	11	lysosome acyltransferase activity heparan-alpha-glucosaminide N-acetyltransferase activity membrane integral to membrane transferase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
211566_x_at	0.259	7.654	2.448	2.694e-02	0.250	-3.620	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	2	27966985, 27967060	U19178	9577	2p23.2	Hs.258314	20	nuclear ubiquitin ligase complex peroxisome targeting sequence binding tumor necrosis factor receptor binding protein binding nucleus cytoplasm double-strand break repair apoptosis response to DNA damage stimulus signal transduction response to ionizing radiation chromatin modification G2/M transition DNA damage checkpoint polyubiquitin binding positive regulation of DNA repair positive regulation of anti-apoptosis BRCA1-A complex BRISC complex
218028_at	0.263	6.133	2.448	2.694e-02	0.250	-3.620	ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	1	-43601658	NM_016031	64834	1p34.2	Hs.25597	7	protein binding endoplasmic reticulum fatty acid biosynthetic process membrane integral to membrane
201546_at	-0.345	8.841	-2.448	2.695e-02	0.250	-3.620	TRIP12	thyroid hormone receptor interactor 12	2	-230340173	NM_004238	9320	2q36.3	Hs.591633	10	ubiquitin-protein ligase activity binding cellular_component intracellular cytosol protein modification process protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process protein complex thyroid hormone receptor binding	Ubiquitin mediated proteolysis
1560320_a_at	0.243	4.492	2.448	2.696e-02	0.250	-3.621	UNQ2963	hypothetical LOC283314	12	7152179	AL833364	283314	12p13.31	Hs.715709	2
202257_s_at	0.246	7.130	2.448	2.696e-02	0.250	-3.621	CD2BP2	CD2 (cytoplasmic tail) binding protein 2	16	-30269588, -30269588	NM_006110	10421	16p11.2	Hs.202677	21	nuclear mRNA splicing, via spliceosome protein binding cytoplasm
223562_at	0.263	5.127	2.448	2.696e-02	0.250	-3.621	PARVG	parvin, gamma	22	42900168, 42900168, 42908102, 42908102, 42908548, 42908589	AF237772	64098	22q13.2-q13	Hs.658995	13	actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion cell-matrix adhesion cell junction	Focal adhesion
233959_at	0.333	4.603	2.447	2.698e-02	0.250	-3.622	LOC221442	adenylate cyclase 10 pseudogene	6	41176750	W26606	221442	6p21.1	Hs.374076	1
206631_at	0.356	3.049	2.447	2.700e-02	0.250	-3.622	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	14	51850765	NM_000956	5732	14q22	Hs.2090	60	receptor activity G-protein coupled receptor activity prostaglandin E receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway regulation of cell proliferation	Neuroactive ligand-receptor interaction
208659_at	0.484	6.958	2.447	2.700e-02	0.250	-3.622	CLIC1	chloride intracellular channel 1	6	-31806336, -3144481, -2945934	AF034607	1192	6p22.1-p21.2	Hs.414565	36	voltage-gated ion channel activity voltage-gated chloride channel activity protein binding membrane fraction soluble fraction nucleus nuclear envelope cytoplasm cytosol plasma membrane brush border ion transport chloride transport defense response response to unfolded protein signal transduction response to nutrient integral to membrane chloride ion binding chloride channel complex protein complex NF-kappaB binding
206392_s_at	0.392	3.499	2.447	2.701e-02	0.250	-3.622	RARRES1	retinoic acid receptor responder (tazarotene induced) 1	3	-159905133, -159897590	NM_002888	5918	3q25.32	Hs.131269	11	negative regulation of cell proliferation membrane integral to membrane
223367_at	0.389	6.770	2.447	2.701e-02	0.250	-3.623	DNAJC30	DnaJ (Hsp40) homolog, subfamily C, member 30	7	-72733183	BC005056	84277	7q11.23	Hs.647046	6	protein folding heat shock protein binding unfolded protein binding
218409_s_at	-0.233	6.685	-2.447	2.702e-02	0.250	-3.623	DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	10	-22085482	NM_022365	64215	10p12.31	Hs.499000	8	ATPase activator activity DNA binding nucleus endoplasmic reticulum microsome regulation of translation protein folding membrane integral to membrane heat shock protein binding negative regulation of proteolysis regulation of protein secretion unfolded protein binding chaperone binding
214008_at	-0.233	3.005	-2.447	2.702e-02	0.250	-3.623	TWF1	twinfilin, actin-binding protein, homolog 1 (Drosophila)	12	-42473792	N25562	5756	12q12	Hs.189075	9	actin binding protein tyrosine kinase activity intracellular cytoplasm protein amino acid phosphorylation actin cytoskeleton
217733_s_at	0.480	9.649	2.446	2.706e-02	0.250	-3.624	TMSB10	thymosin beta 10	2	84986273	NM_021103	9168	2p11.2	Hs.446574	23	actin binding cytoplasm cytoskeleton actin cytoskeleton organization sequestering of actin monomers
232669_at	0.217	3.667	2.446	2.706e-02	0.250	-3.624	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	AU145409	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
200632_s_at	0.266	6.810	2.446	2.706e-02	0.250	-3.624	NDRG1	N-myc downstream regulated 1	8	-134318595	NM_006096	10397	8q24.3	Hs.372914 Hs.618002	70	protein binding nucleus cytoplasm cytoskeleton plasma membrane response to metal ion mast cell activation
222858_s_at	0.264	5.408	2.446	2.706e-02	0.250	-3.624	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	4	100957003	AI632216	27071	4q25-q27	Hs.436271 Hs.708484	15	protein tyrosine phosphatase activity protein binding phospholipid binding cellular_component cytoplasm protein amino acid dephosphorylation signal transduction membrane	B cell receptor signaling pathway
215275_at	0.224	4.134	2.446	2.707e-02	0.250	-3.624	TRAF3IP3	TRAF3 interacting protein 3	1	207996146	AW963138	80342	1q32.3-q41	Hs.147434	11	membrane integral to membrane
207150_at	0.216	5.323	2.446	2.707e-02	0.250	-3.624	SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	10	50488352	NM_003055	6572	10q11.2	Hs.654374	15	acetylcholine transmembrane transporter activity membrane fraction integral to plasma membrane acetylcholine transport membrane
239998_at	0.217	5.708	2.446	2.708e-02	0.250	-3.625	C10orf53	chromosome 10 open reading frame 53	10	50557689, 50557689	AI990484	282966	10q11.23	Hs.131287	4
204652_s_at	-0.248	5.531	-2.446	2.708e-02	0.250	-3.625	NRF1	nuclear respiratory factor 1	7	129038790, 129057154	NM_005011	4899	7q32	Hs.654363	47	DNA binding nucleus generation of precursor metabolites and energy regulation of transcription from RNA polymerase II promoter regulation of transcription	Huntington's disease
237730_at	0.193	5.252	2.446	2.709e-02	0.250	-3.625	LOC100130700	similar to hCG2038355	16		AA824251	100130700	16p11.1	Hs.97712
239110_s_at	0.327	3.271	2.445	2.713e-02	0.250	-3.626	LOC728190	hypothetical LOC728190	10	-88988405	W79643	728190	10q23.2	Hs.655534 Hs.696346	1
204776_at	0.971	8.293	2.445	2.713e-02	0.250	-3.627	THBS4	thrombospondin 4	5	79366746	NM_003248	7060	5q13	Hs.211426	24	structural molecule activity calcium ion binding protein binding extracellular region extracellular region proteinaceous extracellular matrix substrate-bound cell migration, cell extension cell adhesion heparin binding platelet alpha granule lumen	TGF-beta signaling pathway Focal adhesion ECM-receptor interaction
212740_at	-0.295	6.743	-2.445	2.714e-02	0.250	-3.627	PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4	3	-131880467	BF740111	30849	3q22.1	Hs.149032	9	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding cellular_component cytosol protein amino acid phosphorylation transferase activity	Regulation of autophagy
213438_at	0.330	5.005	2.444	2.716e-02	0.250	-3.627	NFASC	neurofascin homolog (chicken)	1	203064404, 203064404, 203179976	AA995925	23114	1q32.1	Hs.13349	28	protein binding plasma membrane cell adhesion integral to membrane	Cell adhesion molecules (CAMs)
217046_s_at	0.276	5.703	2.444	2.716e-02	0.250	-3.627	AGER	advanced glycosylation end product-specific receptor	6	-32256723, -3555933, -3363712	AJ133822	177	6p21.3	Hs.534342	212	transmembrane receptor activity protein binding extracellular region plasma membrane integral to plasma membrane inflammatory response cell surface receptor linked signal transduction
237251_at	0.262	4.596	2.444	2.716e-02	0.250	-3.628	C1orf92	chromosome 1 open reading frame 92	1	155157047	AI480252	149499	1q23.1	Hs.491734	3
203581_at	-0.275	8.186	-2.444	2.717e-02	0.250	-3.628	RAB4A	RAB4A, member RAS oncogene family	1	227473501	BC002438	5867	1q42-q43	Hs.296169	43	nucleotide binding GTPase activity GTP binding cytoplasm small GTPase mediated signal transduction protein transport membrane	Endocytosis
212904_at	-0.345	9.948	-2.444	2.718e-02	0.250	-3.628	LRRC47	leucine rich repeat containing 47	1	-3686643	AB033011	57470	1p36.32	Hs.268488	5	RNA binding phenylalanine-tRNA ligase activity protein binding translation
201423_s_at	-0.340	8.987	-2.444	2.719e-02	0.250	-3.628	CUL4A	cullin 4A	13	112911086, 112911931	AL037208	8451	13q34	Hs.339735	48	G1/S transition of mitotic cell cycle protein binding DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Nucleotide excision repair Ubiquitin mediated proteolysis
219065_s_at	-0.438	9.125	-2.444	2.719e-02	0.250	-3.628	MEMO1	mediator of cell motility 1	2	-31946398, -31946397	NM_015955	51072	2p22-p21	Hs.444969	10	nucleus cytosol
231468_at	0.241	3.493	2.443	2.721e-02	0.251	-3.629	SH3BP4	SH3-domain binding protein 4	2	235525366	BF224439	23677	2q37.1-q37.2	Hs.516777	12	molecular_function signal transducer activity protein binding cellular_component nucleus coated pit endocytosis cell cycle biological_process membrane clathrin-coated vesicle cytoplasmic vesicle
234854_at	0.225	3.278	2.443	2.722e-02	0.251	-3.630	MDN1	MDN1, midasin homolog (yeast)	6	-90409951	AL096678	23195	6q15	Hs.529948	7	nucleotide binding ATP binding nucleus ATPase activity regulation of protein complex assembly unfolded protein binding
201740_at	0.249	11.255	2.443	2.722e-02	0.251	-3.630	NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	11	47557137	NM_004551	4722	11p11.11	Hs.502528	23	NADH dehydrogenase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport induction of apoptosis NADH dehydrogenase (ubiquinone) activity electron carrier activity membrane electron transport chain negative regulation of cell growth respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
1569315_s_at	0.351	3.075	2.443	2.724e-02	0.251	-3.630	LOC100272228	hypothetical LOC100272228	X	148857423	BC032484	100272228		Hs.496916	4
229537_at	-0.411	4.522	-2.442	2.726e-02	0.251	-3.631	LMO4	LIM domain only 4	1	87566738	AI694521	8543	1p22.3	Hs.436792	21	neural tube closure transcription factor activity transcription factor complex transcription from RNA polymerase II promoter transcription factor binding zinc ion binding regulation of transcription metal ion binding
232311_at	0.308	4.861	2.442	2.726e-02	0.251	-3.631	B2M	beta-2-microglobulin	15	42790976	AU147899	567	15q21-q22.2	Hs.534255 Hs.709313	169	Golgi membrane antigen processing and presentation of peptide antigen via MHC class I protein binding extracellular region Golgi apparatus plasma membrane plasma membrane immune response early endosome membrane MHC class I protein complex	Antigen processing and presentation
236030_at	0.253	6.099	2.442	2.726e-02	0.251	-3.631	RCOR2	REST corepressor 2	11	-63435277	BF528119	283248	11q13.1	Hs.98788	2	transcription factor activity transcription corepressor activity protein binding nucleus transcription factor complex negative regulation of transcription
212550_at	-0.351	6.371	-2.442	2.726e-02	0.251	-3.631	STAT5B	signal transducer and activator of transcription 5B	17	-37604720	AI149535	6777	17q11.2	Hs.719121	128	allantoin metabolic process luteinization natural killer cell differentiation transcription factor activity signal transducer activity calcium ion binding protein binding nucleus cytoplasm citrate metabolic process 2-oxoglutarate metabolic process succinate metabolic process oxaloacetate metabolic process isoleucine metabolic process valine metabolic process creatine metabolic process fatty acid metabolic process signal transduction female pregnancy lactation positive regulation of cell proliferation regulation of steroid metabolic process cytokine-mediated signaling pathway taurine metabolic process lipid storage regulation of cell adhesion regulation of epithelial cell differentiation response to estradiol stimulus cellular response to hormone stimulus T cell differentiation in the thymus glucocorticoid receptor binding positive regulation of multicellular organism growth positive regulation of activated T cell proliferation progesterone metabolic process T cell homeostasis negative regulation of apoptosis positive regulation of interleukin-2 biosynthetic process positive regulation of B cell differentiation positive regulation of gamma-delta T cell differentiation negative regulation of erythrocyte differentiation positive regulation of survival gene product expression positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter creatinine metabolic process development of secondary female sexual characteristics development of secondary male sexual characteristics Peyer's patch development positive regulation of inflammatory response JAK-STAT cascade involved in growth hormone signaling pathway	ErbB signaling pathway Chemokine signaling pathway Jak-STAT signaling pathway Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia
233571_x_at	0.521	8.583	2.442	2.728e-02	0.251	-3.632	PPDPF	pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)	20	61622576	AL121829	79144	20q13.33	Hs.79625	3	multicellular organismal development cell differentiation
220188_at	0.230	3.516	2.442	2.728e-02	0.251	-3.632	JPH3	junctophilin 3	16	86193999	NM_020655	57338	16q24.3	Hs.592068	18	molecular_function protein binding endoplasmic reticulum plasma membrane junctional sarcoplasmic reticulum membrane integral to membrane regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
228957_at	0.227	5.212	2.441	2.730e-02	0.251	-3.632	ZNF362	zinc finger protein 362	1	33494760	AI224880	149076	1p35.1	Hs.524248	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
235619_at	-0.559	8.613	-2.441	2.731e-02	0.251	-3.632	LOC285986	hypothetical protein LOC285986	7		AI681644	285986	7q21.3	Hs.602765	1
221553_at	-0.355	6.559	-2.441	2.733e-02	0.251	-3.633	MAGT1	magnesium transporter 1	X	-76968519	AL136636	84061	Xq21.1	Hs.323562 Hs.710189	14	dolichyl-diphosphooligosaccharide-protein glycotransferase activity endoplasmic reticulum oligosaccharyltransferase complex membrane integral to membrane protein amino acid N-linked glycosylation via asparagine
201270_x_at	-0.370	8.176	-2.441	2.735e-02	0.251	-3.634	NUDCD3	NudC domain containing 3	7	-44388489	NM_015332	23386	7p13-p12	Hs.488171	11
216900_s_at	0.235	3.932	2.440	2.735e-02	0.251	-3.634	CHRNA4	cholinergic receptor, nicotinic, alpha 4	20	-61445108	X89745	1137	20q13.2-q13.3	Hs.10734	90	regulation of action potential response to hypoxia nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity membrane fraction plasma membrane nicotinic acetylcholine-gated receptor-channel complex DNA repair ion transport calcium ion transport response to oxidative stress signal transduction synaptic transmission, cholinergic external side of plasma membrane regulation of dopamine secretion acetylcholine receptor activity integral to membrane sensory perception of pain cell junction dendrite behavioral response to nicotine B cell activation cell soma synapse postsynaptic membrane cognition membrane depolarization regulation of inhibitory postsynaptic membrane potential
213394_at	0.281	6.371	2.440	2.736e-02	0.251	-3.634	MAPKBP1	mitogen-activated protein kinase binding protein 1	15	39853923	AI674759	23005	15q15.1	Hs.513661	6
236860_at	0.800	6.851	2.440	2.738e-02	0.251	-3.635	NPY6R	neuropeptide Y receptor Y6 (pseudogene)	5	137171360	BF968482	4888	5q31	Hs.643466 Hs.713225	4	peptide YY receptor activity receptor activity G-protein coupled receptor activity integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway membrane
203878_s_at	0.269	5.979	2.440	2.739e-02	0.251	-3.635	MMP11	matrix metallopeptidase 11 (stromelysin 3)	22	22445035	NM_005940	4320	22q11.2 22q11.23	Hs.143751	30	metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix proteolysis multicellular organismal development peptidase activity zinc ion binding collagen catabolic process
213366_x_at	0.350	11.912	2.440	2.740e-02	0.252	-3.635	ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	10	7870098	AV711183	509	10p15.1	Hs.271135	18	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) mitochondrion mitochondrion mitochondrial matrix ion transport ATP synthesis coupled proton transport proton transport membrane ATPase activity ATPase activity hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
244872_at	-0.416	5.486	-2.440	2.741e-02	0.252	-3.636	RBBP4	retinoblastoma binding protein 4	1	32889335, 32889545	BE514107	5928	1p35.1	Hs.16003	70	nucleus DNA replication chromatin remodeling cell cycle DNA-dependent ATPase activity negative regulation of cell proliferation Sin3 complex NuRD complex histone binding histone deacetylase binding regulation of transcription
210044_s_at	0.293	6.381	2.439	2.742e-02	0.252	-3.636	LYL1	lymphoblastic leukemia derived sequence 1	19	-13070846	BC002796	4066	19p13.2	Hs.46446	15	DNA binding nucleus transcription regulator activity regulation of transcription
223309_x_at	-0.279	7.849	-2.439	2.743e-02	0.252	-3.637	PNPLA8	patatin-like phospholipase domain containing 8	7	-107899306	BG025248	50640	7q31	Hs.617340	13	lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm
239279_at	0.382	4.233	2.439	2.744e-02	0.252	-3.637	LOC730102	hypothetical protein LOC730102	1		AI862518	730102	1q25.2	Hs.149540
231996_at	-0.419	2.941	-2.439	2.744e-02	0.252	-3.637	N4BP2	NEDD4 binding protein 2	4	39734918	AB037834	55728	4p14	Hs.391463	8	nucleotide binding endonuclease activity protein binding ATP binding cytoplasm hydrolase activity ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
205692_s_at	-0.539	6.968	-2.439	2.744e-02	0.252	-3.637	CD38	CD38 molecule	4	15389028	NM_001775	952	4p15	Hs.479214	105	NAD+ nucleosidase activity receptor activity binding membrane fraction plasma membrane signal transduction metabolic process induction of apoptosis by extracellular signals cell surface integral to membrane hydrolase activity, acting on glycosyl bonds phosphorus-oxygen lyase activity positive regulation of B cell proliferation	Nicotinate and nicotinamide metabolism Metabolic pathways Calcium signaling pathway Hematopoietic cell lineage
206016_at	-0.399	5.393	-2.439	2.744e-02	0.252	-3.637	CCDC22	coiled-coil domain containing 22	X	48978884	NM_014008	28952	Xp11.23	Hs.247700 Hs.26333	6	molecular_function cellular_component biological_process
210241_s_at	0.374	6.667	2.439	2.746e-02	0.252	-3.637	TP53TG1	TP53 target 1 (non-protein coding)	7	-86792599	AB007458	11257	7q21.1	Hs.274329	3	signal transducer activity response to stress
218631_at	0.267	5.876	2.438	2.750e-02	0.252	-3.639	AVPI1	arginine vasopressin-induced 1	10	-99427170	NM_021732	60370	10q24.2	Hs.23918	9	cell cycle
208168_s_at	0.216	3.223	2.438	2.750e-02	0.252	-3.639	CHIT1	chitinase 1 (chitotriosidase)	1	-201451829	NM_003465	1118	1q31-q32	Hs.201688	42	polysaccharide catabolic process chitinase activity extracellular region extracellular space lysosome carbohydrate metabolic process chitin catabolic process immune response chitin binding metabolic process response to bacterium cation binding	Amino sugar and nucleotide sugar metabolism
205384_at	-0.347	9.199	-2.437	2.753e-02	0.252	-3.640	FXYD1	FXYD domain containing ion transport regulator 1	19	40321571, 40322231	NM_005031	5348	19q13.1	Hs.442498	14	ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport chloride transport muscle contraction chloride ion binding chloride channel complex
209793_at	0.286	3.469	2.437	2.754e-02	0.252	-3.640	GRIA1	glutamate receptor, ionotropic, AMPA 1	5	152850276	AL567302	2890	5q31.1 5q33	Hs.519693	58	receptor activity ion channel activity extracellular-glutamate-gated ion channel activity membrane fraction endoplasmic reticulum plasma membrane ion transport signal transduction synaptic transmission kainate selective glutamate receptor activity integral to membrane cell junction alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction Long-term potentiation Long-term depression Amyotrophic lateral sclerosis (ALS)
240947_at	-0.202	3.137	-2.437	2.757e-02	0.252	-3.641	ANO6	anoctamin 6	12	43896036, 43896036, 43896142, 43972732	N36984	196527	12q12	Hs.696326	6	ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex
206986_at	0.240	5.693	2.436	2.757e-02	0.252	-3.641	FGF18	fibroblast growth factor 18	5	170779271	AB007422	8817	5q34	Hs.87191	25	angiogenesis intramembranous ossification endochondral ossification chondrocyte development extracellular region extracellular region extracellular space nucleolus signal transduction cell-cell signaling growth factor activity positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis lung development positive regulation of vascular endothelial growth factor receptor signaling pathway	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
205879_x_at	0.212	6.180	2.436	2.757e-02	0.252	-3.641	RET	ret proto-oncogene	10	42892522, 42892522	BC004257	5979	10q11.2	Hs.350321	421	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity calcium ion binding ATP binding protein amino acid phosphorylation homophilic cell adhesion signal transduction posterior midgut development membrane integral to membrane transferase activity	Endocytosis Pathways in cancer Thyroid cancer
209031_at	0.598	6.696	2.436	2.757e-02	0.252	-3.641	CADM1	cell adhesion molecule 1	11	-114549554	AL519710	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
202236_s_at	-0.553	8.193	-2.436	2.759e-02	0.252	-3.642	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	NM_003051	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
205447_s_at	0.314	4.623	2.436	2.760e-02	0.252	-3.642	MAP3K12	mitogen-activated protein kinase kinase kinase 12	12	-52160546	BE222201	7786	12q13	Hs.713539	22	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding membrane fraction cytoplasm cytosol plasma membrane protein kinase cascade JNK cascade histone phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation protein kinase binding growth cone axon part protein homodimerization activity protein amino acid autophosphorylation	MAPK signaling pathway
223449_at	0.346	6.406	2.436	2.761e-02	0.252	-3.642	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	5	-115807149	AF225425	57556	5q23.1	Hs.156967	11	receptor activity protein binding apoptosis cytoskeleton organization cell surface receptor linked signal transduction multicellular organismal development nervous system development axon guidance organ morphogenesis membrane integral to membrane cell differentiation axon	Axon guidance
212984_at	-0.350	7.170	-2.436	2.761e-02	0.252	-3.642	ATF2	activating transcription factor 2	2	-175647251	BE786164	1386	2q32	Hs.592510	98	transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity intracellular nucleus cytosol regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding protein dimerization activity	MAPK signaling pathway
212410_at	-0.318	9.692	-2.436	2.762e-02	0.252	-3.643	EFHA1	EF-hand domain family, member A1	13	-20964838	AI346431	221154	13q12.11	Hs.412103	7	calcium ion binding
204493_at	0.526	3.728	2.435	2.763e-02	0.252	-3.643	BID	BH3 interacting domain death agonist	22	-16596905, -16596905	NM_001196	637	22q11.1	Hs.591054	111	release of cytochrome c from mitochondria death receptor binding protein binding membrane fraction cytoplasm mitochondrion mitochondrial outer membrane cytosol cytosol induction of apoptosis via death domain receptors activation of pro-apoptotic gene products membrane regulation of mitochondrial membrane permeability neuron apoptosis	p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer
1555501_s_at	-0.322	4.778	-2.435	2.764e-02	0.253	-3.643	RSRC1	arginine/serine-rich coiled-coil 1	3	159310585	BC010357	51319	3q25.32	Hs.591283	5	alternative nuclear mRNA splicing, via spliceosome protein binding nucleus protein amino acid phosphorylation nucleocytoplasmic transport RNA splicing nuclear speck response to antibiotic
214228_x_at	0.316	6.145	2.435	2.766e-02	0.253	-3.644	TNFRSF4	tumor necrosis factor receptor superfamily, member 4	1	-1136568	AJ277151	7293	1p36	Hs.129780	48	receptor activity tumor necrosis factor receptor activity integral to plasma membrane immune response cell surface membrane positive regulation of B cell proliferation negative regulation of gene-specific transcription T cell proliferation negative regulation of transcription factor activity positive regulation of immunoglobulin secretion	Cytokine-cytokine receptor interaction
227358_at	0.275	5.645	2.435	2.767e-02	0.253	-3.644	ZBTB46	zinc finger and BTB domain containing 46	20	-61846321	Z39566	140685	20q13.33	Hs.585028	5	nucleic acid binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1552506_at	0.168	3.694	2.434	2.769e-02	0.253	-3.645	CRB2	crumbs homolog 2 (Drosophila)	9	125158268	NM_173689	286204	9q33.3	Hs.710092	7	calcium ion binding extracellular region plasma membrane visual perception integral to membrane response to stimulus
241961_at	0.744	7.894	2.434	2.770e-02	0.253	-3.645	TECRL	trans-2,3-enoyl-CoA reductase-like	4	-64826779	AI822082	253017	4q13.1	Hs.227752	1	cytoplasm lipid metabolic process membrane integral to membrane oxidoreductase activity, acting on the CH-CH group of donors
203743_s_at	-0.356	7.018	-2.434	2.770e-02	0.253	-3.645	TDG	thymine-DNA glycosylase	12	102883722	NM_003211	6996	12q24.1	Hs.584809	47	damaged DNA binding protein binding nucleus nucleoplasm nucleoplasm base-excision repair mismatch repair response to DNA damage stimulus metabolic process pyrimidine-specific mismatch base pair DNA N-glycosylase activity DNA N-glycosylase activity mismatched DNA binding depyrimidination	Base excision repair
218200_s_at	0.218	11.708	2.434	2.771e-02	0.253	-3.646	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	7	140042949	NM_004546	4708	7q34	Hs.655788	8	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
207137_at	0.243	5.276	2.433	2.774e-02	0.253	-3.646	NFKBIL2	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2	8	-145624970	NM_013432	4796	8q24.3	Hs.675285	6	transcription corepressor activity protein binding cytoplasm cytoplasmic sequestering of transcription factor
208064_s_at	0.262	3.381	2.433	2.774e-02	0.253	-3.646	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	18	53170718	NM_015879	51046	18q21.31	Hs.23172	7	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein amino acid glycosylation N-glycan processing glycosphingolipid biosynthetic process oligosaccharide metabolic process membrane integral to membrane integral to Golgi membrane
210876_at	0.249	4.033	2.433	2.775e-02	0.253	-3.647	ANXA2P1	annexin A2 pseudogene 1	4	-154448070	M62896	303	4q21-q31	Hs.546235	2
202798_at	-0.396	7.933	-2.433	2.776e-02	0.253	-3.647	SEC24B	SEC24 family, member B (S. cerevisiae)	4	110574419	NM_006323	10427	4q25	Hs.292472	11	Golgi membrane transporter activity protein binding cytoplasm endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport zinc ion binding membrane membrane organization vesicle-mediated transport COPII vesicle coat perinuclear region of cytoplasm
233734_s_at	0.224	6.507	2.433	2.777e-02	0.253	-3.647	OSBPL5	oxysterol binding protein-like 5	11	-3064921	AW271225	114879	11p15.4	Hs.436166	17	protein binding cytosol lipid transport Golgi to plasma membrane transport oxysterol binding steroid metabolic process cholesterol metabolic process cholesterol transport
202605_at	0.310	6.700	2.433	2.777e-02	0.253	-3.647	GUSB	glucuronidase, beta	7	-65063107	NM_000181	2990	7q21.11	Hs.255230	45	beta-glucuronidase activity lysosome carbohydrate metabolic process glycosaminoglycan catabolic process metabolic process cation binding	Pentose and glucuronate interconversions Starch and sucrose metabolism Glycosaminoglycan degradation Porphyrin and chlorophyll metabolism Drug metabolism - other enzymes Metabolic pathways Lysosome
223894_s_at	-0.387	8.902	-2.433	2.778e-02	0.253	-3.648	AKTIP	AKT interacting protein	16	-52082692	BC001134	64400	16q12.2	Hs.380897	14	protein binding cytoplasm plasma membrane apoptosis endosome organization lysosome organization endosome to lysosome transport protein transport small conjugating protein ligase activity HOPS complex post-translational protein modification early endosome to late endosome transport regulation of protein metabolic process FHF complex
203684_s_at	-0.507	5.618	-2.433	2.779e-02	0.253	-3.648	BCL2	B-cell CLL/lymphoma 2	18	-59136166, -58941558	M13994	596	18q21.3 18q21.33	Hs.150749	705	G1/S transition of mitotic cell cycle protein phosphatase type 2A complex cell morphogenesis response to acid ovarian follicle development ureteric bud development branching involved in ureteric bud morphogenesis behavioral fear response response to hypoxia B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development renal system process intracellular membrane fraction nucleus cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol calcineurin complex protein amino acid dephosphorylation melanin metabolic process oxygen and reactive oxygen species metabolic process regulation of nitrogen utilization anti-apoptosis humoral immune response response to oxidative stress actin filament organization female pregnancy cell aging response to nutrient transcription factor binding cell death positive regulation of cell proliferation male gonad development activation of pro-apoptotic gene products response to radiation response to heat response to external stimulus response to toxin post-embryonic development organ morphogenesis response to inorganic substance response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration membrane integral to membrane cell-cell adhesion transcription activator activity peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis hemopoiesis negative regulation of ossification negative regulation of cell growth negative regulation of cell migration response to caffeine hair follicle morphogenesis axon regeneration regulation of protein stability nuclear membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization negative regulation of myeloid cell apoptosis T cell differentiation in the thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine stimulus response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation response to drug response to hydrogen peroxide protein homodimerization activity T cell homeostasis positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment response to peptide hormone stimulus regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis ear development response to estrogen stimulus regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability protein heterodimerization activity focal adhesion formation positive regulation of pigmentation during development spleen development thymus development gut morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue response to glucocorticoid stimulus BH3 domain binding defense response to virus regulation of cell cycle response to protein stimulus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport apoptosis in response to endoplasmic reticulum stress	Apoptosis Focal adhesion Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Prostate cancer Small cell lung cancer
232717_at	0.231	3.174	2.432	2.780e-02	0.253	-3.648	KALRN	kalirin, RhoGEF kinase	3	125296247, 125296247, 125296247, 125786195	AU147936	8997	3q21.2	Hs.8004	24	nucleotide binding magnesium ion binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity ATP binding intracellular cytoplasm protein amino acid phosphorylation intracellular signaling cascade nervous system development actin cytoskeleton vesicle-mediated transport transferase activity regulation of Rho protein signal transduction
205441_at	-0.263	7.035	-2.432	2.783e-02	0.253	-3.649	OCEL1	occludin/ELL domain containing 1	19	17198054	NM_024578	79629	19p13.11	Hs.422676	3
212013_at	0.398	6.142	2.432	2.784e-02	0.253	-3.650	PXDN	peroxidasin homolog (Drosophila)	2	-1614665	D86983	7837	2p25	Hs.332197	9	peroxidase activity interleukin-1 receptor antagonist activity calcium ion binding protein binding extracellular region immune response response to oxidative stress oxidoreductase activity heme binding hydrogen peroxide catabolic process oxidation reduction
1554093_a_at	-0.303	8.125	-2.431	2.786e-02	0.253	-3.650	SNAPC5	small nuclear RNA activating complex, polypeptide 5, 19kDa	15	-64569719	BC014315	10302	15q22.31	Hs.30174	7	transcription factor activity nucleus transcription from RNA polymerase II promoter transcription initiation from RNA polymerase III promoter regulation of transcription
1565613_at	0.222	2.521	2.431	2.788e-02	0.254	-3.651	LOC391081	similar to hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	1		BF939357	391081	1p12
203607_at	-0.423	6.072	-2.431	2.789e-02	0.254	-3.651	INPP5F	inositol polyphosphate-5-phosphatase F	10	121475598, 121475598, 121568775	NM_014937	22876	10q26.11	Hs.369755	7	hydrolase activity
231759_at	-0.427	6.621	-2.431	2.790e-02	0.254	-3.651	TAL2	T-cell acute lymphocytic leukemia 2	9	107464558	NM_005421	6887	9q32	Hs.247978	9	DNA binding protein binding nucleus behavior post-embryonic development thalamus development transcription regulator activity midbrain development multicellular organism growth regulation of transcription
238006_at	0.286	5.293	2.430	2.791e-02	0.254	-3.652	SIN3A	SIN3 homolog A, transcription regulator (yeast)	15	-73448774, -73448774, -73448774	AI760013	25942	15q24.2	Hs.513039	107	negative regulation of transcription from RNA polymerase II promoter kinetochore DNA binding transcription corepressor activity nucleus nucleolus transcription factor binding Sin3 complex	Huntington's disease
202972_s_at	-0.338	5.994	-2.430	2.791e-02	0.254	-3.652	FAM13A	family with sequence similarity 13, member A	4	-89866128, -89866128	AW450403	10144	4q22.1	Hs.97270	7
229034_at	-0.455	4.997	-2.430	2.793e-02	0.254	-3.652	SOBP	sine oculis binding protein homolog (Drosophila)	6	107918009	BF511724	55084	6q21	Hs.445244	4	zinc ion binding metal ion binding
225061_at	-0.513	9.832	-2.430	2.794e-02	0.254	-3.653	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4	15	76343541, 76344043, 76345614	N45231	55466	15q25.1	Hs.513053	5	protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding
216231_s_at	0.348	12.302	2.430	2.794e-02	0.254	-3.653	B2M	beta-2-microglobulin	15	42790976	AW188940	567	15q21-q22.2	Hs.534255 Hs.709313	169	Golgi membrane antigen processing and presentation of peptide antigen via MHC class I protein binding extracellular region Golgi apparatus plasma membrane plasma membrane immune response early endosome membrane MHC class I protein complex	Antigen processing and presentation
202877_s_at	0.392	7.421	2.430	2.794e-02	0.254	-3.653	CD93	CD93 molecule	20	-23007992	W72082	22918	20p11.21	Hs.97199	35	complement component C1q binding receptor activity calcium ion binding protein binding sugar binding plasma membrane phagocytosis cell surface integral to membrane cytoplasmic membrane-bounded vesicle cell-cell adhesion macrophage activation interspecies interaction between organisms
241984_at	0.193	4.793	2.430	2.794e-02	0.254	-3.653	FOXN3	forkhead box N3	14	-88692268, -88692268	BF984444	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
201280_s_at	0.610	6.316	2.429	2.795e-02	0.254	-3.653	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	5	-39407536	NM_001343	1601	5p13	Hs.481980	47	coated pit protein C-terminus binding cell proliferation membrane clathrin coated vesicle membrane cytoplasmic vesicle	Endocytosis
1552546_a_at	0.247	3.209	2.429	2.800e-02	0.254	-3.655	LETM2	leucine zipper-EF-hand containing transmembrane protein 2	8	38363176	NM_144652	137994	8p11.23	Hs.696457	2	mitochondrion membrane integral to membrane
200051_at	-0.195	6.779	-2.429	2.800e-02	0.254	-3.655	SART1	squamous cell carcinoma antigen recognized by T cells	11	65485735	NM_005146	9092	11q13.1	Hs.502883	27	molecular_function nucleus spliceosomal complex cytoplasm cytosol mRNA processing cell cycle arrest RNA splicing induction of apoptosis by intracellular signals positive regulation of cytotoxic T cell differentiation
214898_x_at	0.234	5.600	2.428	2.801e-02	0.254	-3.655	MUC3B	mucin 3B, cell surface associated	7		AB038783	57876	7q22	Hs.489354	9	membrane integral to membrane
201681_s_at	-0.475	7.124	-2.428	2.803e-02	0.254	-3.656	DLG5	discs, large homolog 5 (Drosophila)	10	-79220554	AB011155	9231	10q23	Hs.652690	49	protein binding intracellular cytoplasm plasma membrane cell-cell adherens junction intracellular signaling cascade negative regulation of cell proliferation cell-cell adhesion cell junction receptor signaling complex scaffold activity regulation of apoptosis
204984_at	-0.489	7.219	-2.428	2.804e-02	0.254	-3.656	GPC4	glypican 4	X	-132262729	NM_001448	2239	Xq26.1	Hs.58367	12	extracellular region proteinaceous extracellular matrix extracellular space plasma membrane integral to plasma membrane cell proliferation anatomical structure morphogenesis anchored to membrane heparan sulfate proteoglycan binding
201656_at	0.381	7.315	2.428	2.804e-02	0.254	-3.656	ITGA6	integrin, alpha 6	2	173000559	NM_000210	3655	2q31.1	Hs.133397	114	receptor activity calcium ion binding protein binding cell-substrate junction assembly cell adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Hematopoietic cell lineage Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
213501_at	-0.374	6.331	-2.428	2.805e-02	0.254	-3.656	ACOX1	acyl-Coenzyme A oxidase 1, palmitoyl	17	-71449186	T62985	51	17q24-q25 17q25.1	Hs.464137	26	acyl-CoA dehydrogenase activity acyl-CoA oxidase activity acyl-CoA oxidase activity cytoplasm mitochondrion peroxisome peroxisomal membrane generation of precursor metabolites and energy lipid metabolic process fatty acid beta-oxidation prostaglandin metabolic process spermatogenesis electron carrier activity protein N-terminus binding FAD binding oxidation reduction	Fatty acid metabolism alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
224800_at	-0.321	7.481	-2.428	2.806e-02	0.254	-3.657	WDFY1	WD repeat and FYVE domain containing 1	2	-224448308	AK022888	57590	2q36.1	Hs.708107	5	phosphatidylinositol binding nucleus early endosome cytosol biological_process zinc ion binding metal ion binding
219242_at	-0.354	7.866	-2.428	2.806e-02	0.254	-3.657	CEP63	centrosomal protein 63kDa	3	135687264, 135687264, 135687586, 135687736	NM_025180	80254	3q22.2	Hs.443301	11	DNA damage checkpoint spindle pole protein binding centrosome spindle assembly
206854_s_at	-0.393	6.392	-2.427	2.808e-02	0.254	-3.657	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	NM_003188	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
206098_at	-0.314	3.267	-2.427	2.809e-02	0.254	-3.658	ZBTB6	zinc finger and BTB domain containing 6	9	-124710155	NM_006626	10773	9q33.2	Hs.654596	4	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
220346_at	-0.227	5.740	-2.427	2.810e-02	0.254	-3.658	MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	4	75242692	NM_025001	441024	4q13.3	Hs.479954	2	histidine biosynthetic process magnesium ion binding methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity binding purine nucleotide biosynthetic process one-carbon metabolic process cellular amino acid biosynthetic process methionine biosynthetic process folic acid and derivative biosynthetic process oxidoreductase activity hydrolase activity oxidation reduction
205854_at	0.378	6.770	2.427	2.810e-02	0.254	-3.658	TULP3	tubby like protein 3	12	2870293	AK024246	7289	12p13.3	Hs.655333	7	phosphatidylinositol-4,5-bisphosphate binding nucleus plasma membrane regulation of transcription, DNA-dependent G-protein coupled receptor protein signaling pathway
223504_at	-0.444	5.860	-2.427	2.811e-02	0.254	-3.658	DNAJC27	DnaJ (Hsp40) homolog, subfamily C, member 27	2	-25020008	AL117490	51277	2p23.3	Hs.434993	4	nucleotide binding GTP binding small GTPase mediated signal transduction heat shock protein binding
211903_s_at	0.240	3.918	2.427	2.811e-02	0.254	-3.658	MPL	myeloproliferative leukemia virus oncogene	1	43576061	M90103	4352	1p34	Hs.82906	85	cytokine receptor activity plasma membrane integral to plasma membrane cell surface receptor linked signal transduction cell proliferation	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
225052_at	-0.341	8.284	-2.427	2.811e-02	0.254	-3.658	TMEM203	transmembrane protein 203	9	-139218355	AL520657	94107	9q34.3	Hs.591886	1	membrane integral to membrane
1552721_a_at	0.314	3.048	2.426	2.816e-02	0.255	-3.660	FGF1	fibroblast growth factor 1 (acidic)	5	-141951926, -141951926, -141951926, -141951926, -141951926	NM_033136	2246	5q31	Hs.483635	114	angiogenesis induction of an organ protein binding extracellular region proteinaceous extracellular matrix extracellular space signal transduction multicellular organismal development growth factor activity heparin binding cell proliferation fibroblast growth factor receptor signaling pathway anatomical structure morphogenesis cell differentiation lung development positive regulation of epithelial cell proliferation	MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma
218144_s_at	0.251	6.186	2.425	2.819e-02	0.255	-3.661	INF2	inverted formin, FH2 and WH2 domain containing	14	104226987, 104227002	NM_022489	64423	14q32.33	Hs.24956	10	actin binding cellular component organization Rho GTPase binding actin cytoskeleton organization
228794_at	-0.642	12.513	-2.425	2.820e-02	0.255	-3.661	XIRP2	xin actin-binding repeat containing 2	2	167468220	AA211780	129446	2q24.3	Hs.73680	8	actin binding actin cytoskeleton organization cell junction
219826_at	0.380	6.661	2.425	2.821e-02	0.255	-3.661	ZNF419	zinc finger protein 419	19	62690890	NM_024691	79744	19q13.43	Hs.710285	6	DNA binding intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1553709_a_at	0.194	6.693	2.425	2.822e-02	0.255	-3.662	PRPF38A	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	1	52642806	NM_032284	84950	1p33-p32.1	Hs.5301	5	nucleus spliceosomal complex mRNA processing RNA splicing
204479_at	0.279	6.163	2.425	2.823e-02	0.255	-3.662	OSTF1	osteoclast stimulating factor 1	9	76893217	NM_012383	26578	9q13-q21.2	Hs.494192	17	ossification intracellular cytoplasm signal transduction identical protein binding
224945_at	-0.355	7.411	-2.424	2.824e-02	0.255	-3.662	BTBD7	BTB (POZ) domain containing 7	14	-92823726, -92773648	AI935657	55727	14q32.12	Hs.525549	5	protein binding
1559661_at	-0.320	3.220	-2.424	2.825e-02	0.255	-3.663	ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)	4	183482130	AF195420	55714	4q35.1	Hs.130438	7	signal transduction membrane integral to membrane
201787_at	0.313	6.168	2.424	2.825e-02	0.255	-3.663	FBLN1	fibulin 1	22	44277382, 44277382, 44277382, 44277382	NM_001996	2192	22q13.31	Hs.24601 Hs.593123	55	extracellular matrix structural constituent calcium ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space soluble fraction interspecies interaction between organisms
211081_s_at	-0.315	3.392	-2.424	2.825e-02	0.255	-3.663	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	14	-49954992	Z25426	11183	14q11.2-q21	Hs.130491	14	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding cytoplasm protein amino acid phosphorylation response to stress protein kinase cascade activation of JUN kinase activity transferase activity
238962_at	-0.193	2.441	-2.424	2.826e-02	0.255	-3.663	ZNF681	zinc finger protein 681	19	-23713836	AW305300	148213	19p12	Hs.187337 Hs.399952	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
235300_x_at	-0.483	5.652	-2.424	2.826e-02	0.255	-3.663	RCHY1	ring finger and CHY zinc finger domain containing 1	4	-76623370	AW236209	25898	4q21.1	Hs.48297	20	protein binding nucleus cytoplasm zinc ion binding metal ion binding	p53 signaling pathway Ubiquitin mediated proteolysis
205620_at	0.366	4.997	2.424	2.827e-02	0.255	-3.663	F10	coagulation factor X	13	112825113	NM_000504	2159	13q34	Hs.361463	153	serine-type endopeptidase activity calcium ion binding protein binding phospholipid binding extracellular region extracellular region plasma membrane proteolysis blood coagulation, extrinsic pathway peptidase activity positive regulation of cell migration intrinsic to external side of plasma membrane positive regulation of protein kinase B signaling cascade	Complement and coagulation cascades
225467_s_at	0.241	6.879	2.424	2.827e-02	0.255	-3.663	RDH13	retinol dehydrogenase 13 (all-trans/9-cis)	19	-60247503, -60247503	BG163591	112724	19q13.42	Hs.327631	9	binding oxidoreductase activity oxidation reduction
230259_at	0.207	5.056	2.424	2.828e-02	0.255	-3.664	C10orf125	chromosome 10 open reading frame 125	10	-135018784, -135018647	AI471699	282969	10q26.3	Hs.155823	2	carbohydrate transport
214258_x_at	-0.252	6.675	-2.424	2.828e-02	0.255	-3.664	KAT5	K(lysine) acetyltransferase 5	11	65236064	AA886971	10524	11q13	Hs.397010	88	chromatin chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding nucleus nucleolus cytoplasm double-strand break repair chromatin assembly or disassembly DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator zinc ion binding acyltransferase activity chromatin modification histone acetylation transferase activity androgen receptor signaling pathway Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth interspecies interaction between organisms regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding perinuclear region of cytoplasm androgen receptor binding
1555469_a_at	-0.379	6.361	-2.423	2.831e-02	0.255	-3.665	CLASP2	cytoplasmic linker associated protein 2	3	-33512741	BC029035	23122	3p22.3	Hs.108614	17	condensed chromosome kinetochore protein binding cytoplasm Golgi apparatus centrosome spindle kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity galactoside 2-alpha-L-fucosyltransferase activity regulation of microtubule polymerization or depolymerization microtubule plus-end binding cell division
200971_s_at	0.215	7.264	2.422	2.838e-02	0.256	-3.667	SERP1	stress-associated endoplasmic reticulum protein 1	3	-151742469	NM_014445	27230	3q25.1	Hs.518326 Hs.709270	10	skeletal system development endoplasmic reticulum ribosome glucose metabolic process protein amino acid glycosylation response to stress plasma membrane organization post-embryonic development multicellular organismal aging protein transport membrane integral to membrane endoplasmic reticulum unfolded protein response positive regulation of insulin secretion positive regulation of translation positive regulation of organ growth muscle organ morphogenesis positive regulation of growth hormone secretion intracellular protein transmembrane transport
218559_s_at	0.554	8.284	2.422	2.839e-02	0.256	-3.667	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	20	-38747930	NM_005461	9935	20q11.2-q13.1	Hs.169487	29	transcription factor activity nucleus transcription factor complex cytoplasm segment specification sensory organ development respiratory gaseous exchange transcription factor binding rhombomere 5 development rhombomere 6 development brain segmentation inner ear morphogenesis sequence-specific DNA binding negative regulation of erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter
217025_s_at	0.298	6.030	2.421	2.840e-02	0.256	-3.667	DBN1	drebrin 1	5	-176816219, -176816219	AL110225	1627	5q35.3	Hs.130316	32	actin binding profilin binding intracellular cytoplasm actin filament organization multicellular organismal development nervous system development cell differentiation dendrite actomyosin regulation of neuronal synaptic plasticity regulation of dendrite development
206052_s_at	-0.363	6.785	-2.421	2.841e-02	0.256	-3.668	SLBP	stem-loop binding protein	4	-1664324	NM_006527	7884	4p16.3	Hs.298345	27	mRNA binding nucleus nucleoplasm cytoplasm mRNA processing histone mRNA 3'-end processing ribonucleoprotein complex
230947_at	0.258	6.486	2.421	2.842e-02	0.256	-3.668	SEPT12	septin 12	16	-4767675	AI890919	124404	16p13.3	Hs.126780	6	nucleotide binding stress fiber protein binding protein binding GTP binding GTP binding cytoplasm spindle cell cycle GDP binding midbody septin complex cleavage furrow phosphoinositide binding protein homodimerization activity protein homodimerization activity perinuclear region of cytoplasm cell division
1554250_s_at	0.345	4.744	2.421	2.844e-02	0.256	-3.669	TRIM73	tripartite motif-containing 73	7	74862838	BC033812	375593	7q11.23	Hs.632307 Hs.661254	5	protein binding intracellular zinc ion binding metal ion binding
220342_x_at	-0.330	5.882	-2.421	2.844e-02	0.256	-3.669	EDEM3	ER degradation enhancer, mannosidase alpha-like 3	1	-182926247	NM_017992	80267	1q24-q25	Hs.523811	10	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen response to unfolded protein membrane
219423_x_at	0.405	4.158	2.420	2.845e-02	0.256	-3.669	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	1	-6446757, -6443800	NM_003790	8718	1p36.2	Hs.462529	30	receptor activity tumor necrosis factor receptor activity protein binding extracellular region cytosol plasma membrane integral to plasma membrane cell surface receptor linked signal transduction induction of apoptosis by extracellular signals regulation of apoptosis	Cytokine-cytokine receptor interaction
219836_at	0.264	4.081	2.420	2.848e-02	0.256	-3.670	ZBED2	zinc finger, BED-type containing 2	3	-112794436	NM_024508	79413	3q13.2	Hs.136912	3	DNA binding zinc ion binding metal ion binding
1561503_at	-0.909	8.934	-2.420	2.848e-02	0.256	-3.670	MYLK4	myosin light chain kinase family, member 4	6	-2608861	AK096893	340156	6p25.2	Hs.127830	4	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity
228524_at	0.166	5.225	2.420	2.848e-02	0.256	-3.670	ADCK5	aarF domain containing kinase 5	8	145568538	BE856488	203054	8q24.3	Hs.283374	4	protein serine/threonine kinase activity membrane integral to membrane kinase activity transferase activity
213108_at	-0.682	7.743	-2.420	2.849e-02	0.256	-3.670	CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	5	-149579247	AW131813	815	5q32	Hs.716391	97	G1/S transition of mitotic cell cycle nucleotide binding calmodulin-dependent protein kinase activity calmodulin binding ATP binding plasma membrane calcium ion transport transferase activity cell junction glutamate receptor binding presynaptic membrane synapse protein amino acid autophosphorylation regulation of neurotransmitter secretion regulation of neuronal synaptic plasticity positive regulation of NF-kappaB transcription factor activity	ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma
218111_s_at	-0.345	6.252	-2.420	2.849e-02	0.256	-3.670	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase	12	22090425	NM_018686	55907	12p12.1	Hs.311346	13	nucleus N-acylneuraminate cytidylyltransferase activity lipopolysaccharide biosynthetic process transferase activity nucleotidyltransferase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
238090_at	0.240	3.262	2.420	2.850e-02	0.256	-3.671	HGSNAT	heparan-alpha-glucosaminide N-acetyltransferase	8	43114748	BE327420	138050	8p11.1	Hs.600384	11	lysosome acyltransferase activity heparan-alpha-glucosaminide N-acetyltransferase activity membrane integral to membrane transferase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
226155_at	-0.472	7.343	-2.419	2.851e-02	0.256	-3.671	FAM160B1	family with sequence similarity 160, member B1	10	116571492, 116571492	AB046820	57700	10q25.3	Hs.192619	2
1561383_at	0.197	2.426	2.419	2.853e-02	0.256	-3.672	LOC284661	hypothetical LOC284661	1	4371970	AK093498	284661	1p36.32	Hs.278112	2
231178_at	0.539	5.558	2.419	2.854e-02	0.256	-3.672	SPATA4	spermatogenesis associated 4	4	-177342718	BG150360	132851	4q34.2	Hs.481235	4	molecular_function cellular_component cytoplasm apoptosis spermatogenesis
211628_x_at	0.308	12.146	2.419	2.854e-02	0.256	-3.672	FTHP1	ferritin, heavy polypeptide pseudogene 1	6		J04755	2509	6p21.3-p12	Hs.453583	1
212785_s_at	-0.284	7.489	-2.419	2.856e-02	0.256	-3.672	LARP7	La ribonucleoprotein domain family, member 7	4	113777568, 113778060	AA160181	51574	4q25	Hs.713663	11	nucleotide binding RNA binding nucleus nucleoplasm cytoplasm Golgi apparatus RNA processing ribonucleoprotein complex
235970_at	-0.390	5.684	-2.419	2.856e-02	0.256	-3.673	LCORL	ligand dependent nuclear receptor corepressor-like	4	-17453941	AI807408	254251	4p15.31	Hs.446201 Hs.661849 Hs.677572	9	DNA binding RNA polymerase II transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription
228075_x_at	0.273	6.925	2.418	2.857e-02	0.256	-3.673	TFB1M	transcription factor B1, mitochondrial	6	-155620481	AI341648	51106	6q25.1-q25.3	Hs.279908	15	rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity DNA binding mitochondrion methyltransferase activity rRNA methyltransferase activity transferase activity mitochondrial nucleoid regulation of transcription
224858_at	-0.256	8.015	-2.418	2.857e-02	0.256	-3.673	ZDHHC5	zinc finger, DHHC-type containing 5	11	57192049	AK023130	25921	11q12.1	Hs.27239	5	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
243747_at	0.301	3.739	2.418	2.859e-02	0.257	-3.673	ZNF599	zinc finger protein 599	19	-39940818	AI222019	148103	19q13.11	Hs.590961	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209435_s_at	0.329	6.310	2.418	2.861e-02	0.257	-3.674	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	1	-154183253, -154183253	BC000265	9181	1q21-q22	Hs.655209	28	cell morphogenesis guanyl-nucleotide exchange factor activity intracellular cytoplasm Golgi apparatus spindle microtubule tight junction intracellular protein transport actin filament organization negative regulation of microtubule depolymerization cell cycle mitosis intracellular signaling cascade microtubule binding zinc ion binding diacylglycerol binding cell junction Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction regulation of cell proliferation metal ion binding Rac GTPase binding cell division	Pathogenic Escherichia coli infection - EHEC
206625_at	-0.767	6.668	-2.418	2.861e-02	0.257	-3.674	PRPH2	peripherin 2 (retinal degeneration, slow)	6	-42772310	NM_000322	5961	6p21.2-p12.3	Hs.654489	57	protein binding cell adhesion visual perception membrane integral to membrane response to stimulus retina development in camera-type eye	Amyotrophic lateral sclerosis (ALS)
225373_at	0.243	6.153	2.417	2.863e-02	0.257	-3.674	C10orf54	chromosome 10 open reading frame 54	10	-73177318	BE271644	64115	10q22.1	Hs.47382	9	receptor activity membrane integral to membrane
238886_at	0.241	4.886	2.417	2.863e-02	0.257	-3.675	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	14	-74667923	BF056141	10972	14q24.3	Hs.74137	22	protein binding microsome ER-Golgi intermediate compartment Golgi apparatus cis-Golgi network protein transport membrane integral to membrane vesicle-mediated transport melanosome zymogen granule membrane regulated secretory pathway vesicle targeting, to, from or within Golgi
222774_s_at	-0.509	4.425	-2.417	2.863e-02	0.257	-3.675	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2	16	-45672942	AI335263	81831	16q11	Hs.444046	6	receptor activity membrane integral to membrane
203420_at	-0.237	8.181	-2.417	2.864e-02	0.257	-3.675	FAM8A1	family with sequence similarity 8, member A1	6	17708496	NM_016255	51439	6p22-p23	Hs.95260	6	membrane integral to membrane
222123_s_at	0.321	4.272	2.417	2.864e-02	0.257	-3.675	HIF3A	hypoxia inducible factor 3, alpha subunit	19	51492144, 51493498, 51498715	AK021881	64344	19q13.32	Hs.420830	12	DNA binding signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction transcription regulator activity
218526_s_at	-0.321	6.841	-2.417	2.864e-02	0.257	-3.675	RANGRF	RAN guanine nucleotide release factor	17	8132713	NM_014185	29098	17p13	Hs.408233	6	guanyl-nucleotide exchange factor activity nucleus cytoplasm protein transport
220650_s_at	0.210	5.813	2.417	2.865e-02	0.257	-3.675	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5	16	65840355	NM_004594	6553	16q22.1	Hs.439650	11	cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane sodium ion binding
216843_x_at	0.220	6.238	2.417	2.867e-02	0.257	-3.676	PMS2L1	postmeiotic segregation increased 2-like 1 pseudogene	7	-99756198	U38964	5379	7q22.1	Hs.634244 Hs.661055 Hs.709266	7	molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding
221736_at	-0.233	7.053	-2.416	2.868e-02	0.257	-3.676	KIAA1219	KIAA1219	20	36534899	AA156777	57148	20q11.23	Hs.655758	9	GTPase activator activity protein binding intracellular regulation of small GTPase mediated signal transduction
210030_at	0.207	5.575	2.416	2.869e-02	0.257	-3.676	DOHH	deoxyhypusine hydroxylase/monooxygenase	19	-3441819, -3441819	BC002817	83475	19p13.3	Hs.515064 Hs.609012	8	iron ion binding protein binding cellular_component peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine deoxyhypusine monooxygenase activity metal ion binding oxidation reduction
206074_s_at	-0.295	7.187	-2.416	2.869e-02	0.257	-3.677	HMGA1	high mobility group AT-hook 1	6	34312554, 34312627, 34314545	NM_002131	3159	6p21	Hs.518805 Hs.703764	95	chromatin AT DNA binding transcription factor activity nucleus transcription factor complex chromosome cytosol DNA unwinding during replication nucleosome disassembly loss of chromatin silencing regulation of transcription, DNA-dependent protein complex assembly provirus integration initiation of viral infection enzyme binding ligand-dependent nuclear receptor transcription coactivator activity peroxisome proliferator activated receptor binding interspecies interaction between organisms positive regulation of transcription retinoid X receptor binding
211970_x_at	0.430	10.771	2.416	2.870e-02	0.257	-3.677	ACTG1	actin, gamma 1	17	-77091593	BG026805	71	17q25	Hs.514581	102	nucleotide binding structural constituent of cytoskeleton ATP binding cytoplasm cytoskeleton cell motion identical protein binding response to calcium ion	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
207058_s_at	-0.349	3.965	-2.416	2.871e-02	0.257	-3.677	PARK2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	6	-161688579	NM_004562	5071	6q25.2-q27	Hs.132954 Hs.716115 Hs.716151 Hs.716168	259	ubiquitin-protein ligase activity protein binding nucleus cytoplasm Golgi apparatus central nervous system development zinc ion binding ligase activity acid-amino acid ligase activity protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding perinuclear region of cytoplasm	Ubiquitin mediated proteolysis Parkinson's disease
1554782_at	-0.224	5.975	-2.416	2.872e-02	0.257	-3.677	C2orf19	chromosome 2 open reading frame 19	2		BC031945	394261	2q37.3		3
244109_at	0.298	4.104	2.416	2.872e-02	0.257	-3.677	WDR38	WD repeat domain 38	9	126655575	BF515709	401551	9q33.3	Hs.343383	1
221851_at	0.282	4.153	2.416	2.873e-02	0.257	-3.678	DCAF15	DDB1 and CUL4 associated factor 15	19	13924318	AI073983	90379	19p13.12	Hs.443636	2	modification-dependent protein catabolic process
202528_at	0.270	4.983	2.415	2.874e-02	0.257	-3.678	GALE	UDP-galactose-4-epimerase	1	-23994675, -23994675, -23994675	NM_000403	2582	1p36-p35	Hs.632380	29	UDP-glucose 4-epimerase activity UDP-glucose 4-epimerase activity binding cytosol carbohydrate metabolic process isomerase activity galactose catabolic process protein homodimerization activity cellular metabolic process coenzyme binding	Galactose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
219276_x_at	-0.403	6.639	-2.415	2.875e-02	0.257	-3.678	C9orf82	chromosome 9 open reading frame 82	9	-26830682	NM_024828	79886	9p21.2	Hs.178357	10
223383_at	-0.382	7.351	-2.415	2.875e-02	0.257	-3.678	ZNRF1	zinc and ring finger 1	16	73590415	AL136903	84937	16q23.1	Hs.427284	11	protein binding lysosome endosome zinc ion binding membrane ligase activity modification-dependent protein catabolic process cell junction cytoplasmic vesicle synapse metal ion binding
228891_at	-0.437	8.904	-2.415	2.875e-02	0.257	-3.678	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	9	-91181971, -91165525	N93399	10507	9q22.2	Hs.494406	29	receptor activity receptor binding anti-apoptosis immune response cell adhesion multicellular organismal development nervous system development membrane integral to membrane cell differentiation positive regulation of axonogenesis	Axon guidance
201691_s_at	-0.430	2.976	-2.415	2.876e-02	0.257	-3.679	TPD52	tumor protein D52	8	-81109659, -81109659	NM_005079	7163	8q21	Hs.368433	27	calcium ion binding cytoplasm endoplasmic reticulum anatomical structure morphogenesis B cell differentiation protein homodimerization activity secretion protein heterodimerization activity perinuclear region of cytoplasm
210472_at	0.283	4.314	2.415	2.876e-02	0.257	-3.679	MT1G	metallothionein 1G	16	-55258153	BC005311	4495	16q13	Hs.433391	17	copper ion binding protein binding zinc ion binding cadmium ion binding metal ion binding
212983_at	-0.311	7.749	-2.415	2.878e-02	0.257	-3.679	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	11	-522241	NM_005343	3265	11p15.5	Hs.37003	344	nucleotide binding GTP binding intracellular membrane fraction cytoplasm Golgi apparatus plasma membrane plasma membrane endocytosis apoptosis chemotaxis cell surface receptor linked signal transduction Ras protein signal transduction Ras protein signal transduction cell aging protein C-terminus binding positive regulation of cell proliferation visual learning organ morphogenesis actin cytoskeleton organization regulation of synaptic transmission, GABAergic positive regulation of Rac protein signal transduction negative regulation of neuron apoptosis regulation of long-term neuronal synaptic plasticity striated muscle cell differentiation	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Endocytosis Axon guidance VEGF signaling pathway Focal adhesion Tight junction Gap junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Pathways in cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
1554478_a_at	-0.454	5.292	-2.415	2.878e-02	0.257	-3.679	HEATR3	HEAT repeat containing 3	16	48657381	BC033077	55027	16q12.1	Hs.313917	3	binding
215412_x_at	0.301	5.382	2.415	2.879e-02	0.257	-3.680	PMS2L2	postmeiotic segregation increased 2-like 2 pseudogene	7	-74815899, 72114615	AB017007	5380	7q11-q22	Hs.292996 Hs.661055 Hs.675888	4	molecular_function ATP binding cellular_component mismatch repair biological_process mismatched DNA binding
206227_at	0.581	8.100	2.415	2.879e-02	0.257	-3.680	CILP	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	15	-63275389	NM_003613	8483	15q22	Hs.442180	20	alkaline phosphatase activity nucleotide diphosphatase activity extracellular region proteinaceous extracellular matrix extracellular space negative regulation of insulin-like growth factor receptor signaling pathway extracellular matrix part
209067_s_at	-0.291	9.175	-2.415	2.879e-02	0.257	-3.680	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	D89092	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
228519_x_at	0.211	7.307	2.415	2.879e-02	0.257	-3.680	CIRBP	cold inducible RNA binding protein	19	1220266, 1220266	AW027567	1153	19p13.3	Hs.634522 Hs.664127	17	nucleotide binding RNA binding protein binding nucleus nucleoplasm response to cold
210460_s_at	-0.371	10.033	-2.414	2.883e-02	0.257	-3.681	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	AB033605	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
1570627_at	0.226	4.230	2.414	2.883e-02	0.257	-3.681	TCEB3	transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)	1	23942442	BC019949	6924	1p36.1	Hs.15535	26	DNA binding protein binding nucleus nucleoplasm cytoplasm regulation of transcription from RNA polymerase II promoter integral to membrane transcription regulator activity regulation of transcription
205338_s_at	0.227	4.924	2.414	2.885e-02	0.257	-3.681	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	NM_001922	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
213591_at	0.328	5.751	2.413	2.886e-02	0.257	-3.682	ALDH7A1	aldehyde dehydrogenase 7 family, member A1	5	-125906816	AU149534	501	5q31	Hs.483239	19	aldehyde dehydrogenase (NAD) activity L-aminoadipate-semialdehyde dehydrogenase activity cellular_component mitochondrion cellular aldehyde metabolic process sensory perception of sound oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways
240767_x_at	0.226	6.060	2.413	2.886e-02	0.257	-3.682	RP11-470P4.2	hypothetical LOC100130426	9	78981498	AA398770	100130426	9q21.2	Hs.662256
232259_s_at	0.249	4.425	2.413	2.886e-02	0.257	-3.682	LOC100009676	hypothetical LOC100009676	3	102877963	BC003066	100009676	3q12.3	Hs.715553	4
213663_s_at	-0.516	4.391	-2.412	2.891e-02	0.258	-3.683	FAM134B	family with sequence similarity 134, member B	5	-16526146, -16526146	AI740515	54463	5p15.1	Hs.481704	4	membrane integral to membrane
225196_s_at	0.272	8.105	2.412	2.891e-02	0.258	-3.683	MRPS26	mitochondrial ribosomal protein S26	20	2974674	AF308301	64949	20p13	Hs.18946	10	mitochondrion mitochondrial small ribosomal subunit ribosome DNA damage response, detection of DNA damage peptide biosynthetic process
239198_at	-0.303	5.284	-2.412	2.892e-02	0.258	-3.684	EZH1	enhancer of zeste homolog 1 (Drosophila)	17	-38105818	BG470312	2145	17q21.1-q21.3	Hs.194669	14	DNA binding chromatin binding nucleus nucleolus methyltransferase activity anatomical structure morphogenesis chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription
212327_at	-0.278	9.537	-2.412	2.894e-02	0.258	-3.684	LIMCH1	LIM and calponin homology domains 1	4	41057560, 41309675	AK026815	22998	4p13	Hs.335163	10	actin binding zinc ion binding actomyosin structure organization metal ion binding
218939_at	0.243	6.114	2.412	2.895e-02	0.258	-3.685	LETM1	leucine zipper-EF-hand containing transmembrane protein 1	4	-1783003	NM_012318	3954	4p16.3	Hs.120165	11	calcium ion binding protein binding mitochondrion mitochondrial inner membrane membrane integral to membrane cristae formation
218256_s_at	-0.364	7.448	-2.411	2.897e-02	0.258	-3.685	NUP54	nucleoporin 54kDa	4	-77254840	NM_017426	53371	4q21.1	Hs.430435	16	nucleocytoplasmic transporter activity protein binding nucleus nuclear pore nucleoplasm cytoplasm protein targeting nucleocytoplasmic transport protein transport membrane mRNA transport intracellular protein transmembrane transport
235866_at	-0.181	4.911	-2.411	2.897e-02	0.258	-3.685	C9orf85	chromosome 9 open reading frame 85	9	73716242	AW339510	138241	9q21.13	Hs.534190	4
223524_s_at	-0.823	7.397	-2.411	2.897e-02	0.258	-3.685	TMEM108	transmembrane protein 108	3	134239860	BC000568	66000	3q21	Hs.191616	8	molecular_function cellular_component biological_process membrane integral to membrane
231321_s_at	-0.209	3.243	-2.411	2.898e-02	0.258	-3.685	ACER3	alkaline ceramidase 3	11	76249564	AI681372	55331	11q13.5	Hs.23862	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ceramide metabolic process membrane integral to membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	Sphingolipid metabolism
202689_at	0.177	6.868	2.411	2.899e-02	0.258	-3.686	RBM15B	RNA binding motif protein 15B	3	51403770	NM_013286	29890	3p21.2	Hs.118738	6	nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus mRNA processing nucleocytoplasmic transport RNA splicing negative regulation of transcription interspecies interaction between organisms
221386_at	0.212	2.859	2.411	2.901e-02	0.258	-3.686	OR3A2	olfactory receptor, family 3, subfamily A, member 2	17	-3127933	NM_002551	4995	17p13.3	Hs.647414	6	receptor activity olfactory receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell response to stimulus	Olfactory transduction
223667_at	-0.280	2.561	-2.411	2.901e-02	0.258	-3.686	FKBP7	FK506 binding protein 7	2	-179036638	AF092137	51661	2q31.2	Hs.410378	7	peptidyl-prolyl cis-trans isomerase activity calcium ion binding protein binding endoplasmic reticulum endoplasmic reticulum lumen protein folding isomerase activity
242473_at	0.206	3.528	2.411	2.901e-02	0.258	-3.686	TRAF4	TNF receptor-associated factor 4	17	24095149	BF000155	9618	17q11-q12	Hs.8375	22	DNA binding protein binding nucleus cytoplasm signal transduction multicellular organismal development zinc ion binding regulation of apoptosis metal ion binding	Pathways in cancer Small cell lung cancer
241440_at	0.636	4.760	2.410	2.902e-02	0.258	-3.687	FLJ30375	hypothetical protein LOC440982	3		BF108881	440982	3q24	Hs.535724	1
207605_x_at	0.282	3.952	2.410	2.903e-02	0.258	-3.687	ZNF117	zinc finger protein 117	7	-64072264	NM_024498	51351	7q11.21	Hs.250693	5	molecular_function transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent biological_process zinc ion binding metal ion binding
211119_at	-0.563	3.249	-2.410	2.904e-02	0.258	-3.687	ESR2	estrogen receptor 2 (ER beta)	14	-63769499, -63763503, -63763503	AF060555	2100	14q23.2	Hs.525392 Hs.660607	488	transcription factor activity transcription coactivator activity steroid binding protein binding nucleus mitochondrion regulation of transcription, DNA-dependent signal transduction cell-cell signaling zinc ion binding estrogen receptor activity negative regulation of cell growth estrogen receptor signaling pathway sequence-specific DNA binding metal ion binding receptor antagonist activity
227536_at	-0.301	7.368	-2.410	2.905e-02	0.258	-3.688	ZC3H13	zinc finger CCCH-type containing 13	13	-45434314	AI472196	23091	13q14.13	Hs.136102	11	nucleic acid binding zinc ion binding metal ion binding
219570_at	-0.260	6.529	-2.410	2.905e-02	0.258	-3.688	KIF16B	kinesin family member 16B	20	-16200748	NM_024704	55614	20p11.23	Hs.101774	10	nucleotide binding microtubule motor activity protein binding ATP binding microtubule microtubule-based movement cell communication phosphoinositide binding
201504_s_at	-0.310	6.247	-2.410	2.906e-02	0.258	-3.688	TSN	translin	2	122229590	AI435302	7247	2q21.1	Hs.75066	28	nucleus cytoplasm DNA recombination sequence-specific DNA binding
1568640_at	0.267	4.557	2.410	2.907e-02	0.258	-3.688	ASPRV1	aspartic peptidase, retroviral-like 1	2	-70040727	BC012788	151516	2p13.3	Hs.516253	6	aspartic-type endopeptidase activity proteolysis peptidase activity membrane integral to membrane skin development protein maturation by peptide bond cleavage
223193_x_at	0.276	10.789	2.410	2.907e-02	0.258	-3.688	FAM162A	family with sequence similarity 162, member A	3	123585712	AF201944	26355	3q21.1	Hs.584881	8	membrane integral to membrane
209274_s_at	-0.378	10.231	-2.409	2.908e-02	0.258	-3.688	ISCA1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae)	9	-88069282	BC002675	81689	9q21.33	Hs.449291	9	structural molecule activity iron ion binding mitochondrion iron-sulfur cluster assembly metal ion binding iron-sulfur cluster binding
220512_at	0.195	4.901	2.409	2.909e-02	0.258	-3.689	DLC1	deleted in liver cancer 1	8	-13116452, -12985242, -12985242	NM_024767	10395	8p22	Hs.134296	48	neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation
213090_s_at	-0.330	6.265	-2.409	2.911e-02	0.258	-3.689	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	20	-59983248	AI744029	6874	20q13.33	Hs.18857	36	transcription factor activity transcription coactivator activity protein binding nucleus transcription factor TFIID complex nucleolus cytoplasm regulation of transcription, DNA-dependent transcription initiation from RNA polymerase II promoter general RNA polymerase II transcription factor activity transcription initiation factor activity transcription factor TFTC complex interspecies interaction between organisms	Basal transcription factors Huntington's disease
218105_s_at	0.377	7.228	2.409	2.912e-02	0.258	-3.690	MRPL4	mitochondrial ribosomal protein L4	19	10223639, 10223639	NM_015956	51073	19p13.2	Hs.279652	10	structural constituent of ribosome intracellular mitochondrion ribosome translation
227409_at	-0.389	6.106	-2.409	2.912e-02	0.258	-3.690	PPP1R3E	protein phosphatase 1, regulatory (inhibitor) subunit 3E	14	-22834952	AA167748	90673	14q11.2	Hs.601513 Hs.672733	3	carbohydrate metabolic process glycogen metabolic process
202771_at	0.299	4.516	2.409	2.913e-02	0.258	-3.690	FAM38A	family with sequence similarity 38, member A	16	-87309088	NM_014745	9780	16q24.3	Hs.513807 Hs.592074	8	endoplasmic reticulum membrane integral to membrane ER-Golgi intermediate compartment membrane
214966_at	0.292	4.938	2.408	2.915e-02	0.258	-3.691	GRIK5	glutamate receptor, ionotropic, kainate 5	19	-47194312	S40369	2901	19q13.2	Hs.367799	17	receptor activity ion channel activity extracellular-glutamate-gated ion channel activity plasma membrane ion transport synaptic transmission kainate selective glutamate receptor activity integral to membrane cell junction synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
1555789_s_at	-0.266	6.167	-2.408	2.915e-02	0.258	-3.691	PHF23	PHD finger protein 23	17	-7079070	AY099328	79142	17p13.1	Hs.647432	4	protein binding zinc ion binding metal ion binding
212338_at	0.399	2.782	2.408	2.916e-02	0.258	-3.691	MYO1D	myosin ID	17	-27843740	AA621962	4642	17q11-q12	Hs.658000	7	nucleotide binding motor activity actin binding calmodulin binding ATP binding myosin complex
240147_at	0.263	5.635	2.408	2.918e-02	0.258	-3.692	C7orf50	chromosome 7 open reading frame 50	7	-1003148	AA830578	84310	7p22.3	Hs.653258	5
201027_s_at	-0.283	7.408	-2.408	2.919e-02	0.258	-3.692	EIF5B	eukaryotic translation initiation factor 5B	2	99320265	NM_015904	9669	2q11.2	Hs.158688	15	nucleotide binding translation initiation factor activity translation initiation factor activity GTPase activity protein binding GTP binding cytoplasm translation regulation of translational initiation regulation of translational initiation
214020_x_at	0.273	6.182	2.407	2.921e-02	0.259	-3.692	ITGB5	integrin, beta 5	3	-125964484	BE138575	3693	3q21.2	Hs.536663	55	receptor activity protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
229887_at	0.200	6.288	2.407	2.921e-02	0.259	-3.693	ALS2CL	ALS2 C-terminal like	3	-46685682, -46685682	AI672049	259173	3p21.31	Hs.517937	7	GTPase activator activity cytoplasm endosome organization protein localization cytoplasmic membrane-bounded vesicle Rab GTPase binding identical protein binding
222027_at	-0.303	5.243	-2.407	2.922e-02	0.259	-3.693	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	1	-203948569	AW515443	64710	1q32.1	Hs.213061 Hs.652429	19	nucleus
219782_s_at	-0.231	3.378	-2.407	2.922e-02	0.259	-3.693	ZNF771	zinc finger protein 771	16	30326235	NM_016643	51333	16p11.2	Hs.148584	2	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
202293_at	-0.586	6.084	-2.407	2.923e-02	0.259	-3.693	STAG1	stromal antigen 1	3	-137538688	AW168948	10274	3q22.3	Hs.412586	11	chromatin protein binding nucleus cell cycle chromosome segregation mitosis cell division	Cell cycle
235644_at	-0.334	2.679	-2.406	2.926e-02	0.259	-3.694	CCDC138	coiled-coil domain containing 138	2	108769650	BF213953	165055	2q12.3	Hs.362702	2
203582_s_at	-0.267	7.410	-2.406	2.926e-02	0.259	-3.694	RAB4A	RAB4A, member RAS oncogene family	1	227473501	NM_004578	5867	1q42-q43	Hs.296169	43	nucleotide binding GTPase activity GTP binding cytoplasm small GTPase mediated signal transduction protein transport membrane	Endocytosis
201737_s_at	-0.609	8.084	-2.406	2.927e-02	0.259	-3.694	MARCH6	membrane-associated ring finger (C3HC4) 6	5	10406827	NM_005885	10299	5p15.2	Hs.432862	8	endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding
204196_x_at	0.218	3.483	2.406	2.928e-02	0.259	-3.695	PKNOX1	PBX/knotted 1 homeobox 1	21	43267711	NM_004571	5316	21q22.3	Hs.431043	25	angiogenesis specific RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex cytoplasm hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity
219572_at	0.211	5.622	2.406	2.928e-02	0.259	-3.695	CADPS2	Ca++-dependent secretion activator 2	7	-121745713	NM_017954	93664	7q31.3	Hs.708214	12	calcium ion binding exocytosis lipid binding protein transport membrane cell junction cytoplasmic vesicle synapse
214953_s_at	0.358	6.705	2.406	2.928e-02	0.259	-3.695	APP	amyloid beta (A4) precursor protein	21	-26174732	X06989	351	21q21.2 21q21.3	Hs.434980	835	serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity iron ion binding copper ion binding extracellular region extracellular region cytoplasm Golgi apparatus plasma membrane integral to plasma membrane coated pit cellular copper ion homeostasis endocytosis cell adhesion Notch signaling pathway heparin binding cell death zinc ion binding cell surface peptidase inhibitor activity platelet alpha granule lumen acetylcholine receptor binding identical protein binding metal ion binding neuromuscular process neuron apoptosis	Alzheimer's disease
227588_s_at	0.214	4.120	2.406	2.930e-02	0.259	-3.695	C7orf20	chromosome 7 open reading frame 20	7	882716	AA058854	51608	7p22.3	Hs.107387	9	molecular_function protein binding cellular_component biological_process
243346_at	-0.374	9.852	-2.406	2.930e-02	0.259	-3.695	LMOD3	leiomodin 3 (fetal)	3	-69238728	BF109621	56203	3p14.1	Hs.350621	9	tropomyosin binding cytoplasm cytoskeleton
227313_at	0.259	6.746	2.405	2.931e-02	0.259	-3.696	CNPY4	canopy 4 homolog (zebrafish)	7	99555200	AI870866	245812	7q22.1	Hs.632293	5	extracellular region
216593_s_at	-0.227	6.118	-2.405	2.932e-02	0.259	-3.696	PIGC	phosphatidylinositol glycan anchor biosynthesis, class C	1	-170677219	AB000359	5279	1q23-q25	Hs.188456	12	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring glycosyl groups phosphatidylinositol N-acetylglucosaminyltransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
229478_x_at	0.277	3.137	2.405	2.934e-02	0.259	-3.697	BIVM	basic, immunoglobulin-like variable motif containing	13	102249399	AW274311	54841	13q32-q33.1	Hs.288809	6	nucleus cytoplasm
203977_at	0.202	7.185	2.405	2.935e-02	0.259	-3.697	TAZ	tafazzin	X	153293070	NM_000116	6901	Xq28	Hs.409911	35	cytoplasm mitochondrion mitochondrion muscle contraction skeletal muscle tissue development metabolic process acyltransferase activity membrane integral to membrane hemopoiesis cardiolipin biosynthetic process mitochondrial respiratory chain complex I assembly cristae formation mitochondrial ATP synthesis coupled electron transport 1-acylglycerophosphocholine O-acyltransferase activity cardiac muscle tissue development cardiac muscle contraction
1555500_s_at	0.244	6.004	2.405	2.936e-02	0.259	-3.697	SLC2A4RG	SLC2A4 regulator	20	61841654	BC013687	56731	20q13.33	Hs.435126	10	transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
214211_at	0.551	9.115	2.404	2.937e-02	0.259	-3.697	FTH1	ferritin, heavy polypeptide 1	11	-61488332	AA083483	2495	11q13	Hs.524910 Hs.645560	55	ferroxidase activity protein binding iron ion transport intracellular sequestering of iron ion immune response intracellular ferritin complex ferric iron binding negative regulation of cell proliferation oxidoreductase activity oxidation reduction	Porphyrin and chlorophyll metabolism
209398_at	-0.467	8.565	-2.404	2.938e-02	0.259	-3.698	HIST1H1C	histone cluster 1, H1c	6	-26163946	BC002649	3006	6p21.3	Hs.7644	17	nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly nucleosome positioning
217074_at	0.239	5.303	2.404	2.938e-02	0.259	-3.698	SMOX	spermine oxidase	20	4077449	AK025938	54498	20p13	Hs.433337	17	cytoplasm electron carrier activity oxidoreductase activity spermine catabolic process polyamine oxidase activity oxidation reduction
206896_s_at	0.410	5.585	2.404	2.940e-02	0.259	-3.698	GNG7	guanine nucleotide binding protein (G protein), gamma 7	19	-2462217	NM_005145	2788	19p13.3	Hs.515544	12	behavioral fear response signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction receptor guanylyl cyclase signaling pathway locomotory behavior regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling	Chemokine signaling pathway
224926_at	-0.435	8.013	-2.404	2.941e-02	0.259	-3.699	EXOC4	exocyst complex component 4	7	132588362, 132588362	AB051486	60412	7q31	Hs.321273	30	exocyst cytoplasm vesicle docking during exocytosis protein transport protein N-terminus binding	Tight junction
225353_s_at	0.675	5.245	2.403	2.945e-02	0.260	-3.700	C1QC	complement component 1, q subcomponent, C chain	1	22842704	AI184968	714	1p36.11	Hs.467753	43	extracellular region extracellular region nucleus nucleolus cytoplasm complement activation, classical pathway negative regulation of granulocyte differentiation innate immune response negative regulation of macrophage differentiation	Complement and coagulation cascades Prion diseases Systemic lupus erythematosus
1598_g_at	0.340	8.594	2.403	2.945e-02	0.260	-3.700	GAS6	growth arrest-specific 6	13	113546896, 113574925, 113577228	L13720	2621	13q34	Hs.646346	45	receptor binding calcium ion binding extracellular region signal transduction cell proliferation organ regeneration regulation of growth
204332_s_at	-0.427	6.159	-2.403	2.947e-02	0.260	-3.700	AGA	aspartylglucosaminidase	4	-178588917	M64073	175	4q32-q33	Hs.207776	36	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity lysosome protein deglycosylation hydrolase activity protein maturation	Other glycan degradation Lysosome
227892_at	-0.594	9.418	-2.403	2.947e-02	0.260	-3.701	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit	1	56883577	AA855042	5563	1p31	Hs.437039	67	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytosol protein amino acid phosphorylation fatty acid biosynthetic process cholesterol biosynthetic process signal transduction transferase activity regulation of fatty acid oxidation	Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM)
233541_at	0.184	6.007	2.403	2.948e-02	0.260	-3.701	LOC644714	hypothetical protein LOC644714	3		AK026206	644714	3p21.31	Hs.712889
200053_at	0.248	10.154	2.402	2.948e-02	0.260	-3.701	SPAG7	sperm associated antigen 7	17	-4803243	NM_004890	9552	17p13.2	Hs.90436	7	nucleic acid binding protein binding nucleus
1553363_at	0.227	4.519	2.402	2.948e-02	0.260	-3.701	C6orf195	chromosome 6 open reading frame 195	6	-2567970	NM_152554	154386	6p25.2	Hs.680574	4
204058_at	0.421	9.331	2.402	2.949e-02	0.260	-3.701	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	6	-83976828	AL049699	4199	6q12	Hs.21160	24	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway
238365_s_at	0.255	2.443	2.402	2.949e-02	0.260	-3.701	C1orf228	chromosome 1 open reading frame 228	1	44912980	AI638342	339541	1p34.1	Hs.173679	1	binding
201773_at	-0.338	8.216	-2.402	2.950e-02	0.260	-3.701	ADNP	activity-dependent neuroprotector homeobox	20	-48940289	NM_015339	23394	20q13.13	Hs.570355	10	chromatin binding transcription factor activity dolichyl-phosphate beta-D-mannosyltransferase activity protein binding extracellular space intracellular nucleus nucleolus regulation of transcription, DNA-dependent GPI anchor biosynthetic process zinc ion binding dolichol metabolic process negative regulation of neuron apoptosis sequence-specific DNA binding metal ion binding
206999_at	-0.378	3.048	-2.402	2.951e-02	0.260	-3.702	IL12RB2	interleukin 12 receptor, beta 2	1	67545634	NM_001559	3595	1p31.3-p31.2	Hs.479347	41	receptor activity cytokine receptor activity integral to plasma membrane cell surface receptor linked signal transduction positive regulation of cell proliferation membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
204042_at	-0.418	6.999	-2.402	2.951e-02	0.260	-3.702	WASF3	WAS protein family, member 3	13	26029839	AB020707	10810	13q12	Hs.635221	19	actin binding cytoplasm cytoskeleton protein complex assembly actin filament polymerization	Adherens junction Fc gamma R-mediated phagocytosis
230409_at	0.230	4.023	2.402	2.952e-02	0.260	-3.702	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	1	113734997, 113734997	AI738585	260425	1p12-p11.2	Hs.486189	13	nucleotide binding protein binding ATP binding nucleus plasma membrane tight junction cell junction interspecies interaction between organisms	Tight junction
238035_at	-0.268	6.181	-2.402	2.952e-02	0.260	-3.702	SP3	Sp3 transcription factor	2	-174481504, -174481503	N66313	6670	2q31	Hs.531587	126	ossification natural killer cell differentiation trophectodermal cell differentiation liver development embryonic placenta development DNA binding chromatin binding double-stranded DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding transcription activator activity transcription repressor activity B cell differentiation T cell differentiation megakaryocyte differentiation monocyte differentiation lung development granulocyte differentiation enucleate erythrocyte differentiation metal ion binding embryonic camera-type eye morphogenesis embryonic skeletal system development embryonic process involved in female pregnancy definitive hemopoiesis
227219_x_at	0.233	7.879	2.402	2.953e-02	0.260	-3.702	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	BE857601	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
212840_at	-0.307	3.917	-2.401	2.956e-02	0.260	-3.703	UBXN7	UBX domain protein 7	3	-197564765	BG339560	26043	3q29	Hs.518524	6	protein binding
219835_at	0.225	5.285	2.401	2.957e-02	0.260	-3.703	PRDM8	PR domain containing 8	4	81325447, 81337680	NM_020226	56978	4q21	Hs.373642	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
234317_s_at	0.337	5.728	2.401	2.959e-02	0.260	-3.704	STOX2	storkhead box 2	4	185063502	AL390216	56977	4q35.1	Hs.21958 Hs.696657	3
203255_at	-0.381	6.883	-2.400	2.962e-02	0.260	-3.705	FBXO11	F-box protein 11	2	-47899228, -47893491, -47887562	NM_018693	80204	2p16.3	Hs.352677	12	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm protein modification process ubiquitin-dependent protein catabolic process zinc ion binding histone-arginine N-methyltransferase activity protein ubiquitination peptidyl-arginine C-methyltransferase activity metal ion binding
218020_s_at	-0.288	7.765	-2.400	2.963e-02	0.260	-3.705	ZFAND3	zinc finger, AN1-type domain 3	6	37895284	NM_021943	60685	6pter-p22.3	Hs.36959	8	DNA binding zinc ion binding metal ion binding
206602_s_at	0.304	3.488	2.400	2.963e-02	0.260	-3.705	HOXD3	homeobox D3	2	176737050	NM_006898	3232	2q31.1	Hs.93574	25	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding positive regulation of neuron differentiation embryonic skeletal system morphogenesis cartilage development
236870_at	0.243	2.543	2.400	2.963e-02	0.260	-3.705	IQCF3	IQ motif containing F3	3	51837608	AW958766	401067	3p21.2	Hs.254808	2
214733_s_at	-0.208	6.482	-2.400	2.964e-02	0.260	-3.705	YIPF1	Yip1 domain family, member 1	1	-54089993	AL031427	54432	1p33-p32.1	Hs.11923	9	membrane integral to membrane transport vesicle
203811_s_at	-0.922	7.287	-2.400	2.964e-02	0.260	-3.706	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	1	78243223	NM_007034	11080	1p31.1	Hs.13852	11	protein folding response to unfolded protein response to heat heat shock protein binding unfolded protein binding
206224_at	0.156	5.144	2.400	2.964e-02	0.260	-3.706	CST1	cystatin SN	20	-23676189	NM_001898	1469	20p11.21	Hs.123114	22	cysteine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity
204487_s_at	0.322	5.465	2.400	2.964e-02	0.260	-3.706	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	11	2422796, 2439259	NM_000218	3784	11p15.5	Hs.95162	203	voltage-gated ion channel activity delayed rectifier potassium channel activity protein binding plasma membrane ion transport potassium ion transport muscle contraction sensory perception of sound blood circulation regulation of heart contraction voltage-gated potassium channel complex integral to membrane potassium ion binding cytoplasmic vesicle membrane depolarization	Vibrio cholerae infection
208843_s_at	-0.245	8.512	-2.400	2.965e-02	0.260	-3.706	GORASP2	golgi reassembly stacking protein 2, 55kDa	2	171493956	BC001408	26003	2q31.1-q31.2	Hs.431317	16	protein binding Golgi apparatus Golgi medial cisterna Golgi organization membrane
202058_s_at	-0.592	5.315	-2.399	2.967e-02	0.260	-3.706	KPNA1	karyopherin alpha 1 (importin alpha 5)	3	-123623437	BC002374	3836	3q21	Hs.161008	92	regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
229325_at	-0.333	6.501	-2.399	2.968e-02	0.260	-3.707	ZZZ3	zinc finger, ZZ-type containing 3	1	-77802777	AW515772	26009	1p31.1	Hs.480506	2	DNA binding nucleus zinc ion binding regulation of transcription metal ion binding
207397_s_at	0.203	3.123	2.398	2.972e-02	0.260	-3.708	HOXD13	homeobox D13	2	176665777	NM_000523	3239	2q31.1	Hs.152414	37	skeletal system development transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter multicellular organismal development sequence-specific DNA binding
220254_at	-0.340	3.707	-2.398	2.972e-02	0.260	-3.708	LRP12	low density lipoprotein-related protein 12	8	-105570642	NM_013437	29967	8q22.2-q23.1	Hs.600630	8	receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth
235060_at	-0.327	7.900	-2.398	2.975e-02	0.260	-3.709	LOC100190986	hypothetical LOC100190986	16	-21783123, -21350846, 22423270	AL047052	100190986	16p12.2	Hs.611072 Hs.648439	2
1557528_at	-0.286	4.025	-2.398	2.975e-02	0.260	-3.709	STRADA	STE20-related kinase adaptor alpha	17	-59133926	AI493734	92335	17q23.3	Hs.514402	15	nucleotide binding protein kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation protein export from nucleus cell cycle transferase activity activation of protein kinase activity	mTOR signaling pathway
225463_x_at	-0.289	6.880	-2.398	2.976e-02	0.260	-3.709	GPR89A	G protein-coupled receptor 89A	1	-144475951	BF941168	653519	1q21.1	Hs.559115 Hs.645432	10	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
209654_at	-0.358	7.434	-2.398	2.976e-02	0.260	-3.709	KIAA0947	KIAA0947	5	5475806	BC004902	23379	5p15.32	Hs.449296	3
217722_s_at	-0.220	11.404	-2.397	2.977e-02	0.260	-3.710	NGRN	neugrin, neurite outgrowth associated	15	88609898	NM_016645	51335	15q26.1	Hs.715556 Hs.716378	2	molecular_function nucleus multicellular organismal development nervous system development neuron differentiation
217772_s_at	0.309	9.743	2.397	2.978e-02	0.260	-3.710	MTCH2	mitochondrial carrier homolog 2 (C. elegans)	11	-47595434	NM_014342	23788	11p11.2	Hs.269944	9	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
206669_at	0.215	3.949	2.397	2.978e-02	0.260	-3.710	GAD1	glutamate decarboxylase 1 (brain, 67kDa)	2	171381445, 171381445	NM_013445	2571	2q31	Hs.420036	58	glutamate decarboxylase activity protein binding intracellular glutamate decarboxylation to succinate synaptic transmission vesicle membrane lyase activity protein-pyridoxal-5-phosphate linkage carboxylic acid metabolic process pyridoxal phosphate binding neurotransmitter biosynthetic process	Alanine, aspartate and glutamate metabolism beta-Alanine metabolism Taurine and hypotaurine metabolism Butanoate metabolism Metabolic pathways Type I diabetes mellitus
218493_at	0.369	9.429	2.397	2.978e-02	0.260	-3.710	SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)	16	43828	NM_024571	79622	16p13.3	Hs.15277	7	nucleus U12-type spliceosomal complex mRNA processing RNA splicing
229241_at	0.248	6.996	2.397	2.979e-02	0.260	-3.710	LDHD	lactate dehydrogenase D	16	-73703258	AI623801	197257	16q23.1	Hs.380929	5	D-lactate dehydrogenase (cytochrome) activity protein binding protein binding mitochondrion oxidoreductase activity FAD binding oxidation reduction	Pyruvate metabolism
205226_at	0.458	6.524	2.397	2.979e-02	0.260	-3.710	PDGFRL	platelet-derived growth factor receptor-like	8	17478985	NM_006207	5157	8p22-p21.3	Hs.458573	4	platelet activating factor receptor activity platelet-derived growth factor beta-receptor activity extracellular region biological_process
1564299_at	-0.210	3.053	-2.397	2.981e-02	0.260	-3.711	LOC100127940	hypothetical LOC100127940	7		AK090626	100127940	7p22.3	Hs.638549	1
213772_s_at	-0.241	6.653	-2.397	2.982e-02	0.260	-3.711	GGA2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	16	-23383143	BF196572	23062	16p12	Hs.460336	37	protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding	Lysosome
1561847_at	0.292	4.429	2.397	2.982e-02	0.260	-3.711	NUDT17	nudix (nucleoside diphosphate linked moiety X)-type motif 17	1	-144297851	AA481984	200035	1q21.1	Hs.585066	4	magnesium ion binding mitochondrion hydrolase activity manganese ion binding
205462_s_at	0.393	4.700	2.396	2.983e-02	0.261	-3.711	HPCAL1	hippocalcin-like 1	2	10360490, 10361276	NM_002149	3241	2p25.1	Hs.467696 Hs.580427	20	calcium ion binding protein binding
240412_s_at	0.259	4.025	2.396	2.984e-02	0.261	-3.711	HEATR7B2	HEAT repeat family member 7B2	5	-41033878	AA399262	133558	5p13.1	Hs.97714	3	binding
218473_s_at	0.204	6.537	2.396	2.985e-02	0.261	-3.712	GLT25D1	glycosyltransferase 25 domain containing 1	19	17527510	NM_024656	79709	19p13.11	Hs.418795	10	endoplasmic reticulum endoplasmic reticulum lumen lipopolysaccharide biosynthetic process transferase activity, transferring glycosyl groups
201490_s_at	0.432	8.502	2.396	2.985e-02	0.261	-3.712	PPIF	peptidylprolyl isomerase F	10	80777225	NM_005729	10105	10q22-q23	Hs.381072	13	peptidyl-prolyl cis-trans isomerase activity membrane fraction mitochondrion mitochondrial matrix protein folding isomerase activity peptide binding
242179_s_at	0.250	4.180	2.396	2.986e-02	0.261	-3.712	TSPAN16	tetraspanin 16	19	11267823	AI688554	26526	19p13.2	Hs.579784	2	membrane integral to membrane
37577_at	0.184	3.649	2.396	2.986e-02	0.261	-3.712	ARHGAP19	Rho GTPase activating protein 19	10	-98971919	U79256	84986	10q24.1	Hs.80305	8	GTPase activator activity intracellular nucleus signal transduction
202183_s_at	0.252	7.362	2.396	2.988e-02	0.261	-3.713	KIF22	kinesin family member 22	16	89374	NM_007317	3835	16p11.2	Hs.613351	25	nucleotide binding kinetochore DNA binding microtubule motor activity protein binding ATP binding nucleus microtubule DNA repair microtubule-based movement mitosis
208018_s_at	0.254	4.703	2.395	2.989e-02	0.261	-3.713	HCK	hemopoietic cell kinase	20	30103717	NM_002110	3055	20q11-q12	Hs.655210	125	nucleotide binding non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation mesoderm development membrane transferase activity interspecies interaction between organisms	Chemokine signaling pathway Fc gamma R-mediated phagocytosis
224790_at	0.293	4.969	2.395	2.991e-02	0.261	-3.713	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	8	-131133534	AI023398	50807	8q24.1-q24.2	Hs.655552	19	protein binding cytoplasm ARF GTPase activator activity zinc ion binding membrane regulation of ARF GTPase activity metal ion binding	Endocytosis Fc gamma R-mediated phagocytosis
218842_at	-0.582	6.785	-2.395	2.991e-02	0.261	-3.713	RPAP3	RNA polymerase II associated protein 3	12	-46341982	NM_024604	79657	12q13.11	Hs.437855	6	binding
215437_x_at	-0.217	3.411	-2.395	2.992e-02	0.261	-3.714	BAZ2A	bromodomain adjacent to zinc finger domain, 2A	12	-55275646	BE513659	11176	12q24.3-qter	Hs.314263	11	chromatin silencing at rDNA DNA binding RNA binding protein binding nucleus chromatin silencing complex nucleolus nucleolus organizer region DNA methylation chromatin remodeling regulation of transcription, DNA-dependent zinc ion binding histone deacetylation transcription regulator activity rDNA heterochromatin metal ion binding histone acetyl-lysine binding
227283_at	-0.351	6.540	-2.395	2.992e-02	0.261	-3.714	EFR3B	EFR3 homolog B (S. cerevisiae)	2	25118476	AW138794	22979	2p23.3	Hs.4892	6	binding
224938_at	-0.236	7.096	-2.395	2.993e-02	0.261	-3.714	NUFIP2	nuclear fragile X mental retardation protein interacting protein 2	17	-24606979	AW007746	57532	17q11.2	Hs.462598	13	RNA binding protein binding nucleus cytoplasm Golgi apparatus polysomal ribosome
209200_at	-0.484	10.422	-2.395	2.994e-02	0.261	-3.714	MEF2C	myocyte enhancer factor 2C	5	-88049814, -88049814	AL536517	4208	5q14	Hs.653394	56	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development negative regulation of specific transcription from RNA polymerase II promoter nuclear speck cell differentiation sequence-specific DNA binding positive regulation of survival gene product expression	MAPK signaling pathway
208965_s_at	0.442	4.780	2.394	2.995e-02	0.261	-3.715	IFI16	interferon, gamma-inducible protein 16	1	157246305	BG256677	3428	1q22	Hs.380250	42	DNA binding double-stranded DNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm regulation of transcription, DNA-dependent cell proliferation response to virus transcription repressor activity myeloid cell differentiation monocyte differentiation DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
1554481_a_at	0.184	4.882	2.394	2.995e-02	0.261	-3.715	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	1	29086214	BC039079	2035	1p33-p32	Hs.175437 Hs.708933	79	actin binding structural constituent of cytoskeleton phosphatidylinositol binding nucleus cytoplasm plasma membrane cell cortex blood circulation spectrin spectrin-associated cytoskeleton extrinsic to membrane spectrin binding cortical cytoskeleton cortical actin cytoskeleton organization positive regulation of protein binding protein complex	Tight junction
212049_at	0.210	6.240	2.394	2.996e-02	0.261	-3.715	WIPF2	WAS/WASL interacting protein family, member 2	17	35629099	BG230612	147179	17q21.1-q21.2	Hs.421622 Hs.705989	11	actin binding cytoplasm cytoskeleton
223233_s_at	0.233	4.601	2.394	2.997e-02	0.261	-3.715	CGN	cingulin	1	149750485	AF263462	57530	1q21	Hs.591464	17	motor activity actin binding protein binding tight junction biological_process myosin complex cell junction	Tight junction
216127_at	0.202	5.166	2.393	3.000e-02	0.261	-3.716	PDIA2	protein disulfide isomerase family A, member 2	16	273118	Z84717	64714	16p13.3	Hs.66581	30	response to hypoxia protein disulfide isomerase activity protein binding endoplasmic reticulum endoplasmic reticulum lumen protein folding protein retention in ER lumen isomerase activity cell redox homeostasis
238173_at	0.258	5.570	2.393	3.002e-02	0.261	-3.717	TCEA2	transcription elongation factor A (SII), 2	20	62158882, 62164453	AI393116	6919	20q13.33	Hs.505004 Hs.711562	19	DNA binding RNA polymerase II transcription factor activity transcription elongation regulator activity translation elongation factor activity protein binding nucleus RNA elongation regulation of transcription from RNA polymerase II promoter transcription elongation factor complex zinc ion binding metal ion binding
209454_s_at	-0.364	6.300	-2.393	3.002e-02	0.261	-3.717	TEAD3	TEA domain family member 3	6	-35549351	AF142482	7005	6p21.2	Hs.485205	13	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter female pregnancy
201887_at	-0.296	7.133	-2.393	3.004e-02	0.261	-3.717	IL13RA1	interleukin 13 receptor, alpha 1	X	117745586	NM_001560	3597	Xq24	Hs.496646	25	receptor activity cytokine receptor activity protein binding plasma membrane interleukin-13 receptor complex cell surface receptor linked signal transduction integral to membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
204333_s_at	-0.618	5.117	-2.393	3.004e-02	0.261	-3.717	AGA	aspartylglucosaminidase	4	-178588917	NM_000027	175	4q32-q33	Hs.207776	36	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity lysosome protein deglycosylation hydrolase activity protein maturation	Other glycan degradation Lysosome
221480_at	-0.462	6.856	-2.393	3.004e-02	0.261	-3.718	HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	4	-83493490	BG180941	3184	4q21.1-q21.2	Hs.480073	64	nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding RNA binding protein binding nucleus chromosome regulation of transcription, DNA-dependent RNA processing RNA catabolic process biological_process transcription activator activity heterogeneous nuclear ribonucleoprotein complex telomeric DNA binding
229078_s_at	-0.259	5.583	-2.393	3.005e-02	0.261	-3.718	KIAA1704	KIAA1704	13	44461686	AI073486	55425	13q13-q14	Hs.507922	2
217620_s_at	-0.417	4.009	-2.393	3.006e-02	0.261	-3.718	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	3	-139856920	AA805318	5291	3q22.3	Hs.239818	58	nucleotide binding activation of MAPK activity regulation of cell-matrix adhesion inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex cellular calcium ion homeostasis chemotaxis homophilic cell adhesion signal transduction G-protein coupled receptor protein signaling pathway 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor platelet activation embryonic cleavage insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling	Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
213024_at	-0.570	5.486	-2.392	3.009e-02	0.262	-3.719	TMF1	TATA element modulatory factor 1	3	-69151667	BF593908	7110	3p21-p12	Hs.267632	15	Golgi membrane DNA binding RNA polymerase II transcription factor activity transcription cofactor activity protein binding nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter membrane
1552293_at	0.233	4.680	2.392	3.010e-02	0.262	-3.719	TMEM196	transmembrane protein 196	7	-19725463	NM_152774	256130	7p21.1	Hs.487670	1	membrane integral to membrane
212834_at	-0.339	4.758	-2.391	3.012e-02	0.262	-3.720	DDX52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	17	-33046525	BE963238	11056	17q21.1	Hs.590937	8	nucleotide binding RNA binding helicase activity ATP binding nucleus nucleolus ATP-dependent helicase activity hydrolase activity
218723_s_at	0.566	8.129	2.391	3.013e-02	0.262	-3.720	C13orf15	chromosome 13 open reading frame 15	13	40929541	NM_014059	28984	13q14.11	Hs.507866	16	regulation of cyclin-dependent protein kinase activity protein binding nucleus cytoplasm centrosome cell cycle
208885_at	0.389	5.733	2.391	3.013e-02	0.262	-3.720	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	13	-45598059	J02923	3936	13q14.3	Hs.381099 Hs.710563	36	ruffle phagocytic cup calcium ion binding cytoplasm cytosol actin filament biological_process identical protein binding actin filament binding actin filament bundle formation
209105_at	-0.397	5.994	-2.391	3.013e-02	0.262	-3.720	NCOA1	nuclear receptor coactivator 1	2	24660849	AI672428	8648	2p23	Hs.596314	123	DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding
222705_s_at	0.297	3.865	2.391	3.015e-02	0.262	-3.721	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	13	40261546	BC002702	10166	13q14	Hs.646645 Hs.655240	17	urea cycle L-ornithine transmembrane transporter activity mitochondrial ornithine transport transporter activity binding mitochondrion mitochondrial inner membrane cellular amino acid metabolic process transport membrane integral to membrane
1570410_at	0.213	6.111	2.391	3.016e-02	0.262	-3.721	CYGB	cytoglobin	17	-72035034	BC018822	114757	17q25.3	Hs.95120	28	peroxidase activity oxygen transporter activity cytoplasm transport response to oxidative stress oxygen transport oxygen binding heme binding neuron projection cell soma metal ion binding
239891_x_at	-0.500	8.671	-2.391	3.017e-02	0.262	-3.721	RAB12	RAB12, member RAS oncogene family	18	8599442	AA001052	201475	18p11.22	Hs.270074	2	nucleotide binding GTP binding Golgi apparatus small GTPase mediated signal transduction protein transport membrane
243313_at	-0.370	10.623	-2.390	3.018e-02	0.262	-3.722	SYNPO2L	synaptopodin 2-like	10	-75074649, -75074649	AI141151	79933	10q22.2	Hs.645273	4	actin binding protein binding cytoplasm cytoskeleton
1553533_at	-0.446	5.388	-2.390	3.018e-02	0.262	-3.722	JPH1	junctophilin 1	8	-75309492	NM_020647	56704	8q21	Hs.657367	9	molecular_function microsome plasma membrane muscle organ development structural constituent of muscle junctional sarcoplasmic reticulum membrane integral to membrane sarcoplasmic reticulum Z disc junctional membrane complex regulation of ryanodine-sensitive calcium-release channel activity calcium ion transport into cytosol
242916_at	0.299	4.115	2.390	3.019e-02	0.262	-3.722	CEP110	centrosomal protein 110kDa	9	122890394	AA642477	11064	9q33-q34	Hs.653263	12	protein binding centrosome cell cycle cell division
228023_x_at	-0.256	7.370	-2.390	3.019e-02	0.262	-3.722	AMY2B	amylase, alpha 2B (pancreatic)	1	103898844	AV699389	280	1p21	Hs.484588	19	alpha-amylase activity calcium ion binding extracellular region carbohydrate metabolic process digestion metabolic process hydrolase activity, acting on glycosyl bonds chloride ion binding	Starch and sucrose metabolism Metabolic pathways
209772_s_at	0.231	3.933	2.390	3.020e-02	0.262	-3.722	CD24	CD24 molecule	6	-19611913	X69397	100133941	6q21	Hs.644105 Hs.694721	65	response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation leukocyte migration during inflammatory response immune response-regulating cell surface receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptosis signal transducer activity protein binding membrane fraction plasma membrane oxygen and reactive oxygen species metabolic process heterophilic cell adhesion leukocyte adhesion elevation of cytosolic calcium ion concentration neuromuscular synaptic transmission negative regulation of neuroblast proliferation induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals apoptotic mitochondrial changes external side of plasma membrane Wnt receptor signaling pathway cell migration protein kinase binding carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity regulation of epithelial cell differentiation negative regulation of B cell proliferation neuron projection development anchored to membrane T cell costimulation anchored to external side of plasma membrane microvillus membrane B cell receptor transport into membrane raft chemokine receptor transport out of membrane raft negative regulation of transforming growth factor-beta3 production positive regulation of integrin activation positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPKKK cascade eukaryotic cell surface binding response to estrogen stimulus membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling cilium membrane
233297_s_at	0.196	2.332	2.390	3.023e-02	0.262	-3.723	C13orf38	chromosome 13 open reading frame 38	13	-35703215, -35699181	AL139377	728591	13q13.3	Hs.124519 Hs.656745	3
224125_at	0.208	7.203	2.390	3.023e-02	0.262	-3.723	PLEKHN1	pleckstrin homology domain containing, family N member 1	1	891739	AL136730	84069	1p36.33	Hs.528691	5
208091_s_at	-0.290	8.084	-2.390	3.024e-02	0.262	-3.723	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	7	-55505799	NM_030796	81552	7p11.2	Hs.488307	17
206734_at	-0.337	5.692	-2.389	3.026e-02	0.262	-3.724	JRKL	jerky homolog-like (mouse)	11	95762805	NM_003772	8690	11q21	Hs.105940	4	DNA binding nucleus central nervous system development regulation of transcription
202450_s_at	0.481	6.353	2.389	3.027e-02	0.262	-3.724	CTSK	cathepsin K	1	-149035310	NM_000396	1513	1q21	Hs.632466	80	cysteine-type endopeptidase activity protein binding lysosome proteolysis peptidase activity	Lysosome
1563497_at	-0.380	6.104	-2.389	3.028e-02	0.262	-3.725	USP25	ubiquitin specific peptidase 25	21	16024366	AL833500	29761	21q11.2	Hs.473370	11	ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
234281_at	0.204	3.060	2.389	3.028e-02	0.262	-3.725	ESPNP	espin pseudogene	1	-16890299	AL137798	284729	1p36.13	Hs.548239	1
204497_at	-0.374	8.496	-2.389	3.028e-02	0.262	-3.725	ADCY9	adenylate cyclase 9	16	-3952652	AB011092	115	16p13.3	Hs.391860 Hs.610484	19	nucleotide binding magnesium ion binding adenylate cyclase activity ATP binding integral to plasma membrane cAMP biosynthetic process intracellular signaling cascade membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction GnRH signaling pathway Melanogenesis Vibrio cholerae infection
228057_at	-0.641	9.650	-2.389	3.029e-02	0.262	-3.725	DDIT4L	DNA-damage-inducible transcript 4-like	4	-101326049	AA528140	115265	4q24	Hs.480378	6	cytoplasm negative regulation of signal transduction
210612_s_at	1.025	5.350	2.389	3.029e-02	0.262	-3.725	SYNJ2	synaptojanin 2	6	158322906	AF318616	8871	6q25.3	Hs.434494	18	RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity protein binding membrane dephosphorylation hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
230065_at	0.244	4.487	2.388	3.033e-02	0.262	-3.726	ZNF180	zinc finger protein 180	19	-49671698	AA814415	7733	19q13.2	Hs.22305	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
240465_at	0.358	4.734	2.388	3.036e-02	0.262	-3.727	C4orf32	chromosome 4 open reading frame 32	4	113286001	BF508074	132720	4q25	Hs.23439	4	membrane integral to membrane
212030_at	-0.571	6.806	-2.387	3.036e-02	0.262	-3.727	RBM25	RNA binding motif protein 25	14	72594973	BG251218	58517	14q24.3	Hs.531106	13	nucleotide binding nuclear mRNA splicing, via spliceosome nucleic acid binding mRNA binding cellular_component nucleus cytoplasm nuclear speck
218527_at	-0.192	6.301	-2.387	3.038e-02	0.262	-3.727	APTX	aprataxin	9	-32962607, -32962607, -32962607, -32962607, -32962607	NM_017692	54840	9p13.3	Hs.20158	41	single strand break repair chromatin chromatin binding damaged DNA binding double-stranded DNA binding double-stranded RNA binding intracellular nucleus nucleoplasm nucleolus response to DNA damage stimulus cell death zinc ion binding phosphoglycolate phosphatase activity hydrolase activity regulation of protein stability DNA 5'-adenosine monophosphate hydrolase activity response to hydrogen peroxide metal ion binding protein N-terminus binding
213880_at	-1.943	6.564	-2.387	3.038e-02	0.262	-3.728	LGR5	leucine-rich repeat-containing G protein-coupled receptor 5	12	70120079	AL524520	8549	12q22-q23	Hs.658889	16	receptor activity protein binding plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway protein-hormone receptor activity
1553910_at	0.207	3.279	2.387	3.039e-02	0.262	-3.728	NBPF4	neuroblastoma breakpoint family, member 4	1	-108567485	NM_152488	148545	1p13.3	Hs.511849 Hs.712226	3
218992_at	0.186	8.500	2.387	3.040e-02	0.263	-3.728	C9orf46	chromosome 9 open reading frame 46	9	-5347970	NM_018465	55848	9p24.1	Hs.584242	7	membrane integral to membrane
211762_s_at	-0.603	6.424	-2.387	3.040e-02	0.263	-3.728	KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	17	63462309, -1713110	BC005978	3838	17q24.2	Hs.594238	125	regulation of DNA recombination M phase specific microtubule process G2 phase of mitotic cell cycle protein binding nucleus nuclear pore nucleoplasm cytoplasm DNA metabolic process NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms
213859_x_at	-0.282	3.540	-2.387	3.040e-02	0.263	-3.728	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	4	144654065	AI652586	8467	4q31.1-q31.2	Hs.558422 Hs.710623	37	nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling
228833_s_at	0.219	3.670	2.387	3.041e-02	0.263	-3.728	LOC400027	hypothetical protein LOC400027	12		BE963456	400027	12q12	Hs.597122	1
232740_at	0.208	2.920	2.386	3.043e-02	0.263	-3.729	MCM3APAS	MCM3AP antisense RNA (non-protein coding)	21	46473585	BC002458	114044	21q22.3	Hs.709346	3
242821_at	-0.213	3.756	-2.386	3.043e-02	0.263	-3.729	C9orf93	chromosome 9 open reading frame 93	9	15543096	N94866	203238	9p22.3	Hs.17267	4
213851_at	-0.574	7.019	-2.386	3.044e-02	0.263	-3.729	TMEM110	transmembrane protein 110	3	-52848937	BG031677	375346	3p21.1	Hs.705605	2	molecular_function cellular_component biological_process membrane integral to membrane
228937_at	0.703	3.778	2.386	3.044e-02	0.263	-3.729	C13orf31	chromosome 13 open reading frame 31	13	43351419, 43351968	AI659800	144811	13q14.11	Hs.210586	5
214093_s_at	-0.372	6.861	-2.386	3.045e-02	0.263	-3.729	FUBP1	far upstream element (FUSE) binding protein 1	1	-78186178	AA156865	8880	1p31.1	Hs.567380	28	single-stranded DNA binding transcription factor activity RNA binding protein binding nucleus nucleolus transcription from RNA polymerase II promoter regulation of transcription
213498_at	0.234	4.665	2.386	3.046e-02	0.263	-3.730	CREB3L1	cAMP responsive element binding protein 3-like 1	11	46255803	BG328407	90993	11p11.2	Hs.405961	7	transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent response to unfolded protein membrane integral to membrane sequence-specific DNA binding protein dimerization activity	Melanogenesis Huntington's disease Prostate cancer
225298_at	0.218	8.742	2.386	3.047e-02	0.263	-3.730	PNKD	paroxysmal nonkinesigenic dyskinesia	2	218843358, 218843358, 218896161	AA074597	25953	2q35	Hs.98475	21	nucleus cytoplasm mitochondrion zinc ion binding membrane hydrolase activity metal ion binding
231242_at	0.309	4.022	2.386	3.047e-02	0.263	-3.730	BHLHE41	basic helix-loop-helix family, member e41	12	-26164227	R93946	79365	12p11.23-p12.1	Hs.177841	15	transcription factor activity nucleus regulation of transcription, DNA-dependent cell proliferation organ morphogenesis cell differentiation	Circadian rhythm - mammal
224680_at	-0.220	7.704	-2.385	3.048e-02	0.263	-3.731	TMED4	transmembrane emp24 protein transport domain containing 4	7	-44585286	AL539253	222068	7p13	Hs.598832 Hs.715273	11	endoplasmic reticulum transport membrane integral to membrane
204964_s_at	0.567	8.973	2.385	3.049e-02	0.263	-3.731	SSPN	sarcospan (Kras oncogene-associated gene)	12	26239535, 26239772	NM_005086	8082	12p11.2	Hs.183428	26	integral to plasma membrane muscle contraction cell adhesion dystrophin-associated glycoprotein complex cell junction transport vesicle sarcolemma synapse postsynaptic membrane
233432_at	0.251	4.366	2.385	3.051e-02	0.263	-3.731	LOC646982	twelve-thirteen translocation leukemia gene	13	-39923071, -39819272	AK025090	646982	13q14.11	Hs.287664	1
220864_s_at	0.245	11.127	2.385	3.051e-02	0.263	-3.731	NDUFA13	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	19	19487539	NM_015965	51079	19p13.2	Hs.534453	25	NADH dehydrogenase activity protein binding ATP binding nucleus nucleoplasm cytoplasm mitochondrion mitochondrial respiratory chain complex I protein import into nucleus oxygen and reactive oxygen species metabolic process transport NADH dehydrogenase (ubiquinone) activity induction of apoptosis by extracellular signals membrane integral to membrane negative regulation of translation electron transport chain apoptotic nuclear changes negative regulation of cell growth negative regulation of cell growth negative regulation of transcription, DNA-dependent
225949_at	0.352	6.391	2.385	3.052e-02	0.263	-3.732	NRBP2	nuclear receptor binding protein 2	8	-144987903	N21030	340371	8q24.3	Hs.521926	5	nucleotide binding protein kinase activity protein amino acid phosphorylation
209020_at	-0.303	7.971	-2.385	3.053e-02	0.263	-3.732	C20orf111	chromosome 20 open reading frame 111	20	-42258549	AF217514	51526	20q13.11	Hs.75798	6
214648_at	0.235	3.631	2.385	3.053e-02	0.263	-3.732	GPX5	glutathione peroxidase 5 (epididymal androgen-related protein)	6	28601767	AI207120	2880	6p22.1	Hs.248129	14	glutathione peroxidase activity extracellular region lipid metabolic process response to oxidative stress oxidoreductase activity oxidation reduction	Glutathione metabolism Arachidonic acid metabolism
219562_at	0.339	5.205	2.385	3.053e-02	0.263	-3.732	RAB26	RAB26, member RAS oncogene family	16	2138651	NM_014353	25837	16p13.3	Hs.3797	8	nucleotide binding protein binding GTP binding GTP binding cellular_component plasma membrane small GTPase mediated signal transduction biological_process protein transport regulation of exocytosis intrinsic to plasma membrane exocrine system development
1556820_a_at	-0.393	5.343	-2.385	3.053e-02	0.263	-3.732	DLEU2	deleted in lymphocytic leukemia 2 (non-protein coding)	13	-49454688	H48516	8847	13q14.3	Hs.547964	10
209299_x_at	-0.217	6.478	-2.384	3.054e-02	0.263	-3.732	PPIL2	peptidylprolyl isomerase (cyclophilin)-like 2	22	20350272	BC000022	23759	22q11.21	Hs.438587 Hs.517436	10	ubiquitin ligase complex protein polyubiquitination molecular_function peptidyl-prolyl cis-trans isomerase activity ubiquitin-protein ligase activity nucleus Golgi lumen protein folding biological_process isomerase activity	Ubiquitin mediated proteolysis
222343_at	0.255	4.126	2.384	3.057e-02	0.263	-3.733	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2	111594961, 111594961	AA629050	10018	2q13	Hs.469658	143	peripheral to membrane of membrane fraction in utero embryonic development B cell homeostasis B cell apoptosis kidney development myeloid cell homeostasis protein binding cytoplasm mitochondrion mitochondrial outer membrane cytosol plasma membrane induction of apoptosis cell-matrix adhesion spermatogenesis microtubule binding male gonad development activation of pro-apoptotic gene products post-embryonic development mammary gland development tube lumen formation odontogenesis of dentine-containing tooth T cell homeostasis ear development regulation of organ growth regulation of pigmentation during development spleen development thymus development post-embryonic organ morphogenesis
240391_at	-0.584	5.230	-2.384	3.058e-02	0.263	-3.733	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	7	140042949	AA699958	4708	7q34	Hs.655788	8	mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
221022_s_at	0.180	5.485	2.383	3.060e-02	0.263	-3.734	PMFBP1	polyamine modulated factor 1 binding protein 1	16	-70710497, -70710497	NM_031293	83449	16q22.2	Hs.714939	10	cytoplasm
226310_at	-0.406	5.876	-2.383	3.061e-02	0.263	-3.734	RICTOR	RPTOR independent companion of MTOR, complex 2	5	-38973779	AI743511	253260	5p13.1	Hs.407926	21	guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade	mTOR signaling pathway
217870_s_at	-0.319	9.052	-2.383	3.062e-02	0.263	-3.734	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	1	47572055	NM_016308	51727	1p32	Hs.714325	16	nucleotide binding cytidylate kinase activity uridine kinase activity ATP binding nucleus cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine ribonucleotide biosynthetic process transferase activity phosphotransferase activity, phosphate group as acceptor	Pyrimidine metabolism Metabolic pathways
216466_at	-0.180	2.176	-2.383	3.063e-02	0.263	-3.735	NAV3	neuron navigator 3	12	76749199	AL080104	89795	12q14.3	Hs.655301	9	nucleotide binding nucleus nuclear outer membrane membrane nucleoside-triphosphatase activity
229186_s_at	0.259	4.545	2.382	3.066e-02	0.263	-3.736	ZFP64	zinc finger protein 64 homolog (mouse)	20	-50201223, -50133956	BF196346	55734	20q13.2	Hs.473082	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203611_at	-0.321	6.418	-2.382	3.066e-02	0.263	-3.736	TERF2	telomeric repeat binding factor 2	16	-67947033	NM_005652	7014	16q22.1	Hs.63335	79	nuclear telomere cap complex age-dependent telomere shortening male germ cell nucleus in utero embryonic development DNA binding double-stranded telomeric DNA binding nucleus nucleoplasm chromosome cytoplasm Golgi apparatus telomere maintenance via telomerase cell cycle protein C-terminus binding senescence Mre11 complex telomeric loop formation protection from non-homologous end joining at telomere positive regulation of telomere maintenance negative regulation of telomere maintenance via semi-conservative replication protein homodimerization activity regulation of transcription protein localization to telomere
227998_at	0.340	7.830	2.382	3.069e-02	0.263	-3.736	S100A16	S100 calcium binding protein A16	1	-151845990	AA045184	140576	1q21	Hs.515714	8	calcium ion binding nucleus cytoplasm protein homodimerization activity response to calcium ion
211952_at	-0.321	6.210	-2.382	3.070e-02	0.264	-3.737	IPO5	importin 5	13	97403929	AF339834	3843	13q32.2	Hs.712598	53	protein import into nucleus, docking GTPase inhibitor activity protein binding nucleus nuclear pore nucleolus cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport Ran GTPase binding protein transporter activity interspecies interaction between organisms
1552799_at	-0.240	3.813	-2.381	3.073e-02	0.264	-3.738	TSNARE1	t-SNARE domain containing 1	8	-143291348	NM_145003	203062	8q24.3	Hs.370931	3	protein binding membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
1555626_a_at	0.225	5.154	2.381	3.074e-02	0.264	-3.738	SLAMF1	signaling lymphocytic activation molecule family member 1	1	-158846514	BC012602	6504	1q22-q23	Hs.523660	36	antigen binding transmembrane receptor activity plasma membrane positive regulation of cell proliferation cell surface integral to membrane interspecies interaction between organisms lymphocyte activation
208630_at	0.304	9.543	2.381	3.075e-02	0.264	-3.738	HADHA	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit	2	-26267007	AI972144	3030	2p23	Hs.516032	36	acyl-CoA binding 3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity fatty acid beta-oxidation multienzyme complex long-chain-enoyl-CoA hydratase activity long-chain-3-hydroxyacyl-CoA dehydrogenase activity lyase activity response to drug mitochondrial nucleoid NAD or NADH binding oxidation reduction	Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Biosynthesis of unsaturated fatty acids Metabolic pathways
220646_s_at	0.442	3.337	2.381	3.076e-02	0.264	-3.738	KLRF1	killer cell lectin-like receptor subfamily F, member 1	12	9871343	NM_016523	51348	12p13.2-p12.3	Hs.183125	6	binding sugar binding integral to plasma membrane cell surface receptor linked signal transduction membrane MHC class I receptor activity
1564490_at	0.207	4.663	2.381	3.076e-02	0.264	-3.738	LOC100128830	hypothetical protein LOC100128830	10		AK097584	100128830	10q26.3	Hs.638406	1
212526_at	-0.313	7.006	-2.381	3.076e-02	0.264	-3.739	SPG20	spastic paraplegia 20 (Troyer syndrome)	13	-35773776, -35773776, -35773776	AK002207	23111	13q13.3	Hs.440414	19	cell death
210622_x_at	-0.216	5.865	-2.380	3.079e-02	0.264	-3.739	CDK10	cyclin-dependent kinase 10	16	88280576	AF153430	8558	16q24	Hs.699177	16	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation traversing start control point of mitotic cell cycle negative regulation of cell proliferation transferase activity
204706_at	0.228	6.578	2.380	3.080e-02	0.264	-3.740	INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	9	-138442892	NM_019892	56623	9q34.3	Hs.120998	5	Golgi membrane inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity cellular_component Golgi apparatus lipid metabolic process biological_process membrane hydrolase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
223141_at	-0.260	7.543	-2.380	3.081e-02	0.264	-3.740	UCK1	uridine-cytidine kinase 1	9	-133389004	AK022317	83549	9q34.13	Hs.9597	8	nucleotide binding uridine kinase activity ATP binding cytosol metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways
212673_at	-0.222	7.686	-2.380	3.081e-02	0.264	-3.740	METAP1	methionyl aminopeptidase 1	4	100135810	D42084	23173	4q23	Hs.480364	13	aminopeptidase activity protein binding cytoplasm regulation of translation proteolysis peptidase activity metalloexopeptidase activity cellular process peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding
201017_at	-0.591	8.116	-2.379	3.084e-02	0.264	-3.741	EIF1AX	eukaryotic translation initiation factor 1A, X-linked	X	-20052556	BG149698	1964	Xp22.12	Hs.522590	17	RNA binding translation initiation factor activity cytoplasm cytosol translational initiation
208394_x_at	0.264	3.497	2.379	3.085e-02	0.264	-3.741	ESM1	endothelial cell-specific molecule 1	5	-54309452	NM_007036	11082	5q11.2	Hs.129944	15	regulation of cell growth protein binding insulin-like growth factor binding extracellular region growth factor activity biological_process
202650_s_at	-0.241	6.457	-2.379	3.086e-02	0.264	-3.741	KIAA0195	KIAA0195	17	70964258	NM_014738	9772	17q25.1	Hs.514474	8	membrane integral to membrane
203710_at	0.528	4.914	2.379	3.087e-02	0.264	-3.742	ITPR1	inositol 1,4,5-triphosphate receptor, type 1	3	4510033	NM_002222	3708	3p26-p25	Hs.567295 Hs.715765	87	response to hypoxia ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium channel activity calcium ion binding protein binding endoplasmic reticulum ion transport calcium ion transport signal transduction cell death calcium ion transmembrane transporter activity membrane integral to membrane platelet dense granule membrane platelet dense tubular network membrane	Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Alzheimer's disease Huntington's disease
214057_at	-0.409	4.910	-2.379	3.088e-02	0.264	-3.742	MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	1	-148813658	H71805	4170	1q21	Hs.719112	154	cell fate determination protein binding nucleus nucleoplasm cytoplasm mitochondrion mitochondrial outer membrane anti-apoptosis multicellular organismal development protein channel activity membrane integral to membrane cellular homeostasis cell differentiation response to cytokine stimulus regulation of apoptosis protein heterodimerization activity
218396_at	-0.273	8.899	-2.379	3.088e-02	0.264	-3.742	VPS13C	vacuolar protein sorting 13 homolog C (S. cerevisiae)	15	-59947234, -59931883, -59931881	NM_017684	54832	15q22.2	Hs.511668	6	protein localization
213245_at	0.404	5.967	2.379	3.088e-02	0.264	-3.742	ADCY1	adenylate cyclase 1 (brain)	7	45580649	AL120173	107	7p13-p12	Hs.192215	24	nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane	Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis
209146_at	0.364	5.459	2.379	3.089e-02	0.264	-3.742	SC4MOL	sterol-C4-methyl oxidase-like	4	166468267	AV704962	6307	4q32-q34	Hs.105269 Hs.593050	5	C-4 methylsterol oxidase activity C-4 methylsterol oxidase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane plasma membrane fatty acid biosynthetic process integral to membrane sterol biosynthetic process oxidoreductase activity oxidation reduction	Steroid biosynthesis Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways
210029_at	0.430	6.979	2.379	3.090e-02	0.264	-3.742	IDO1	indoleamine 2,3-dioxygenase 1	8	39890484	M34455	3620	8p12-p11	Hs.840	105	positive regulation of T cell tolerance induction positive regulation of chronic inflammatory response positive regulation of T-helper 2 type immune response tryptophan 2,3-dioxygenase activity tryptophan 2,3-dioxygenase activity cytoplasm cytosol female pregnancy electron carrier activity oxidoreductase activity tryptophan catabolic process to kynurenine NAD metabolic process heme binding indoleamine 2,3-dioxygenase activity metal ion binding oxidation reduction	Tryptophan metabolism Metabolic pathways
229849_at	-0.472	8.410	-2.378	3.090e-02	0.264	-3.743	WIPF3	WAS/WASL interacting protein family, member 3	7	29840865	AI807950	644150	7p14.3	Hs.709280	5	actin binding cytoplasm multicellular organismal development spermatogenesis cell differentiation
209747_at	0.591	6.371	2.378	3.091e-02	0.264	-3.743	TGFB3	transforming growth factor, beta 3	14	-75494194	J03241	7043	14q24	Hs.592317	94	activation of MAPK activity in utero embryonic development type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding extracellular region extracellular region extracellular space nucleus cytoplasm plasma membrane induction of apoptosis salivary gland morphogenesis growth factor activity negative regulation of DNA replication negative regulation of cell proliferation embryonic development positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition positive regulation of pathway-restricted SMAD protein phosphorylation cell growth menstrual cycle phase secretory granule T-tubule positive regulation of bone mineralization negative regulation of transforming growth factor beta receptor signaling pathway mammary gland development extracellular matrix platelet alpha granule lumen response to progesterone stimulus positive regulation of collagen biosynthetic process type I transforming growth factor beta receptor binding odontogenesis identical protein binding cell soma positive regulation of gene-specific transcription positive regulation of gene-specific transcription negative regulation of neuron apoptosis response to estrogen stimulus ossification involved in bone remodeling cell-cell junction organization positive regulation of DNA replication positive regulation of transcription from RNA polymerase II promoter lung alveolus development embryonic neurocranium morphogenesis transforming growth factor beta binding positive regulation of protein secretion positive regulation of filopodium assembly palate development positive regulation of SMAD protein nuclear translocation detection of hypoxia	MAPK signaling pathway Cytokine-cytokine receptor interaction Cell cycle TGF-beta signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hypertrophic cardiomyopathy (HCM)
236523_at	-0.497	10.116	-2.378	3.091e-02	0.264	-3.743	LOC285556	hypothetical protein LOC285556	4		BF435831	285556	4q23	Hs.480371
1561923_a_at	-0.216	3.630	-2.378	3.091e-02	0.264	-3.743	SF3B14	splicing factor 3B, 14 kDa subunit	2	-24143957	AF147425	51639	2pter-p25.1	Hs.177861	14	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus RNA splicing
202825_at	0.219	12.751	2.378	3.092e-02	0.264	-3.743	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	4	186301391	NM_001151	291	4q35	Hs.246506	57	mitochondrial genome maintenance transporter activity ATP:ADP antiporter activity protein binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane integral to plasma membrane generation of precursor metabolites and energy transport adenine transmembrane transporter activity ADP transport ATP transport membrane interspecies interaction between organisms glutamate uptake during transmission of nerve impulse	Calcium signaling pathway Parkinson's disease Huntington's disease
229240_at	-0.311	5.382	-2.378	3.093e-02	0.264	-3.744	ZDHHC21	zinc finger, DHHC-type containing 21	9	-14607032	AI658548	340481	9p22.3	Hs.649522	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
205479_s_at	0.251	6.108	2.378	3.093e-02	0.264	-3.744	PLAU	plasminogen activator, urokinase	10	75340867	NM_002658	5328	10q24	Hs.77274	313	serine-type endopeptidase activity extracellular region plasma membrane proteolysis chemotaxis signal transduction blood coagulation peptidase activity fibrinolysis	Complement and coagulation cascades
235119_at	-0.484	6.176	-2.378	3.096e-02	0.265	-3.744	TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	10	7900678	AI123516	83860	10p15.1	Hs.527688 Hs.709995	12	DNA binding protein binding nucleus transcription factor TFIID complex zinc ion binding regulation of transcription metal ion binding maintenance of protein location in nucleus
1553277_at	-0.229	2.343	-2.377	3.097e-02	0.265	-3.745	RTTN	rotatin	18	-65822020	NM_173630	25914	18q22.2	Hs.654809	3	binding multicellular organismal development determination of left/right symmetry
209510_at	-0.300	8.058	-2.377	3.099e-02	0.265	-3.745	RNF139	ring finger protein 139	8	125556188	AF064801	11236	8q24	Hs.492751	10	receptor activity protein binding endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process regulation of protein ubiquitination metal ion binding
208589_at	-0.363	3.433	-2.377	3.099e-02	0.265	-3.745	TRPC7	transient receptor potential cation channel, subfamily C, member 7	5	-135577021	NM_020389	57113	5q31.1	Hs.591263	13	ion channel activity calcium channel activity calcium ion binding protein binding ion transport calcium ion transport manganese ion transport membrane integral to membrane
227329_at	0.278	5.735	2.376	3.104e-02	0.265	-3.747	ZBTB46	zinc finger and BTB domain containing 46	20	-61846321	AU156821	140685	20q13.33	Hs.585028	5	nucleic acid binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203947_at	-0.293	6.961	-2.376	3.104e-02	0.265	-3.747	CSTF3	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	11	-33119552, -33062705	NM_001326	1479	11p13	Hs.44402	15	nuclear mRNA splicing, via spliceosome RNA binding protein binding intracellular nucleus mRNA polyadenylation mRNA cleavage
220682_s_at	-0.335	4.161	-2.376	3.106e-02	0.265	-3.747	KLHL5	kelch-like 5 (Drosophila)	4	38723053, 38740454	NM_015990	51088	4p14	Hs.272251	6	actin binding protein binding cytoplasm cytoskeleton
205642_at	0.274	5.045	2.376	3.106e-02	0.265	-3.747	CEP110	centrosomal protein 110kDa	9	122890394	NM_007018	11064	9q33-q34	Hs.653263	12	protein binding centrosome cell cycle cell division
219246_s_at	0.234	5.724	2.376	3.107e-02	0.265	-3.747	OGFOD2	2-oxoglutarate and iron-dependent oxygenase domain containing 2	12	122025306	NM_024623	79676	12q24.31	Hs.524817	3	iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction
45297_at	0.275	6.332	2.376	3.107e-02	0.265	-3.748	EHD2	EH-domain containing 2	19	52908412	AI417917	30846	19q13.3	Hs.719225	10	nucleotide binding nucleic acid binding GTPase activity calcium ion binding ATP binding GTP binding membrane fraction nucleus endosome plasma membrane endocytosis hydrolase activity protein domain specific binding cortical actin cytoskeleton organization	Endocytosis
214136_at	0.393	5.697	2.376	3.107e-02	0.265	-3.748	NUDT13	nudix (nucleoside diphosphate linked moiety X)-type motif 13	10	74540215	W80642	25961	10q22.1	Hs.533657	4	hydrolase activity metal ion binding
230524_at	0.197	4.328	2.375	3.108e-02	0.265	-3.748	MPI	mannose phosphate isomerase	15	72969462	AA973383	4351	15q22-qter	Hs.75694	18	mannose-6-phosphate isomerase activity cytoplasm carbohydrate metabolic process zinc ion binding isomerase activity metal ion binding	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
226137_at	-0.353	7.435	-2.375	3.108e-02	0.265	-3.748	ZFHX3	zinc finger homeobox 3	16	-71374286	AI288759	463	16q22.3-q23.1	Hs.598297	26	negative regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor activity, enhancer binding intracellular nucleus transcription factor complex mitochondrion regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity sequence-specific DNA binding metal ion binding
224693_at	0.462	7.862	2.375	3.108e-02	0.265	-3.748	C20orf108	chromosome 20 open reading frame 108	20	54367389	AI133137	116151	20q13.2	Hs.143736 Hs.593629	6	membrane integral to membrane
230544_at	0.216	5.395	2.375	3.110e-02	0.265	-3.748	RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	11	63883200	AW168626	8986	11q11-q13	Hs.105584	16	nucleotide binding magnesium ion binding ribosomal protein S6 kinase activity protein binding ATP binding ATP binding nucleus nucleus regulation of transcription, DNA-dependent protein amino acid phosphorylation protein amino acid phosphorylation protein kinase cascade transferase activity mitogen-activated protein kinase p38 binding mitogen-activated protein kinase p38 binding	MAPK signaling pathway Neurotrophin signaling pathway
222763_s_at	0.341	7.283	2.375	3.111e-02	0.265	-3.749	WDR33	WD repeat domain 33	2	-128238511, -128209431, -128178277	AW161711	55339	2q14.3	Hs.620490	10	molecular_function protein binding nucleus postreplication repair spermatogenesis
1557616_at	0.324	4.342	2.375	3.111e-02	0.265	-3.749	ZNF496	zinc finger protein 496	1	-245530244	AK098030	84838	1q44	Hs.654803	5	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209584_x_at	0.262	4.994	2.375	3.112e-02	0.265	-3.749	APOBEC3C	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	22	37740210	AF165520	27350	22q13.1	Hs.441124	31	protein binding zinc ion binding hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines interspecies interaction between organisms metal ion binding	Atrazine degradation
236172_at	0.213	3.712	2.375	3.113e-02	0.265	-3.749	LTB4R	leukotriene B4 receptor	14	23850544, 23852152	AW206817	1241	14q11.2-q12	Hs.567248	43	nucleotide binding leukotriene B4 receptor activity receptor activity plasma membrane integral to plasma membrane cell motion muscle contraction inflammatory response immune response signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	Neuroactive ligand-receptor interaction
203347_s_at	-0.418	3.808	-2.374	3.116e-02	0.265	-3.750	MTF2	metal response element binding transcription factor 2	1	93317379	NM_007358	22823	1p22.1	Hs.31016	5	DNA binding protein binding nucleus zinc ion binding metal ion binding
209745_at	-0.348	6.512	-2.374	3.116e-02	0.265	-3.750	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)	16	18986427	AK024291	10229	16p13.11-p12.3	Hs.157113	18	iron ion binding nucleus mitochondrion ubiquinone biosynthetic process oxidoreductase activity protein metabolic process	Ubiquinone and other terpenoid-quinone biosynthesis Metabolic pathways
212441_at	-0.297	9.842	-2.374	3.116e-02	0.265	-3.750	KIAA0232	KIAA0232	4	6835359	D86985	9778	4p16.1	Hs.79276	7	nucleotide binding ATP binding
230377_s_at	-0.248	3.815	-2.374	3.117e-02	0.265	-3.750	TBC1D2B	TBC1 domain family, member 2B	15	-76074381	BE504351	23102	15q24.3-q25.1	Hs.719242	2	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
225763_at	-0.451	8.096	-2.373	3.120e-02	0.265	-3.751	RCSD1	RCSD domain containing 1	1	165866097	AI659418	92241	1q22-q24	Hs.493867	5
223644_s_at	0.286	4.429	2.373	3.123e-02	0.266	-3.752	CRYGS	crystallin, gamma S	3	-187738925	AF161703	1427	3q25-qter	Hs.376209	21	structural constituent of eye lens
226032_at	0.274	6.601	2.373	3.124e-02	0.266	-3.752	CASP2	caspase 2, apoptosis-related cysteine peptidase	7	142695523	AU153405	835	7q34-q35	Hs.368982	83	cysteine-type endopeptidase activity cellular_component intracellular proteolysis peptidase activity enzyme binding protein domain specific binding identical protein binding regulation of apoptosis protein maturation by peptide bond cleavage
229016_s_at	0.283	3.511	2.372	3.126e-02	0.266	-3.753	TRERF1	transcriptional regulating factor 1	6	-42300646	AJ277276	55809	6p21.1-p12.1	Hs.485392	10	transcription factor activity intracellular nucleus steroid biosynthetic process cholesterol catabolic process multicellular organismal development transcription factor binding zinc ion binding DNA bending activity RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity homeostatic process regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding regulation of hormone biosynthetic process
236436_at	-0.351	5.710	-2.372	3.128e-02	0.266	-3.754	SLC25A45	solute carrier family 25, member 45	11	-64899238	AI336233	283130	11q13.1	Hs.661604	4	binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane
214955_at	0.238	6.566	2.372	3.130e-02	0.266	-3.754	TMPRSS6	transmembrane protease, serine 6	22	-35791424	AI912086	164656	22q12.3	Hs.370885	16	angiogenesis serine-type endopeptidase activity plasma membrane proteolysis intracellular signaling cascade peptidase activity integral to membrane extracellular matrix organization fibrinolysis
212641_at	-0.367	6.102	-2.372	3.131e-02	0.266	-3.754	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	6	-143114296	AL023584	3097	6q23-q24	Hs.510172	10	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
224747_at	-0.621	7.213	-2.372	3.132e-02	0.266	-3.755	UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2	15	73922676, 73923439	AK000617	92912	15q24.2	Hs.23033	4	nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
205913_at	0.648	5.958	2.372	3.132e-02	0.266	-3.755	PLIN1	perilipin 1	15	-88008602	NM_002666	5346	15q26	Hs.103253	42	protein binding lipid binding monolayer-surrounded lipid storage body lipid catabolic process	PPAR signaling pathway
55662_at	-0.300	6.188	-2.372	3.132e-02	0.266	-3.755	C10orf76	chromosome 10 open reading frame 76	10	-103595345	H27225	79591	10q24.32	Hs.16004	4	membrane integral to membrane
227540_at	0.177	6.605	2.371	3.133e-02	0.266	-3.755	EEFSEC	eukaryotic elongation factor, selenocysteine-tRNA-specific	3	129355002	AW614362	60678	3q21.3	Hs.477498	5	tRNA binding nucleotide binding selenocysteine incorporation translation elongation factor activity GTPase activity GTP binding nucleus cytoplasm translational elongation
201498_at	-0.359	8.884	-2.371	3.135e-02	0.266	-3.756	USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	16	-8893451	AI160440	7874	16p13.3	Hs.706830	38	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity nucleus ubiquitin-dependent protein catabolic process protein C-terminus binding peptidase activity protein deubiquitination interspecies interaction between organisms
237662_at	0.242	3.852	2.371	3.136e-02	0.266	-3.756	LOC646522	hypothetical LOC646522	11		BE858657	646522	11q25	Hs.560000	1
221613_s_at	-0.279	10.164	-2.371	3.137e-02	0.266	-3.756	ZFAND6	zinc finger, AN1-type domain 6	15	78139075	AL136598	54469	15q25.1	Hs.719106	8	molecular_function DNA binding protein binding cellular_component signal transduction biological_process zinc ion binding metal ion binding
1556285_s_at	0.203	8.790	2.370	3.140e-02	0.266	-3.757	PPA2	pyrophosphatase (inorganic) 2	4	-106509682	AF086012	27068	4q25	Hs.654957	13	magnesium ion binding inorganic diphosphatase activity cytoplasm mitochondrion phosphate metabolic process hydrolase activity	Oxidative phosphorylation
211204_at	0.195	4.669	2.370	3.142e-02	0.266	-3.757	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	6	-83976828	L34035	4199	6q12	Hs.21160	24	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction	Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway
204782_at	-0.683	5.606	-2.370	3.143e-02	0.266	-3.758	MLF1	myeloid leukemia factor 1	3	159771646	NM_022443	4291	3q25.1	Hs.85195	14	myeloid progenitor cell differentiation DNA binding nucleus cytoplasm transcription cell cycle cell cycle arrest multicellular organismal development protein domain specific binding cell differentiation
207154_at	0.234	6.219	2.370	3.144e-02	0.266	-3.758	DIO3	deiodinase, iodothyronine, type III	14	101097440	NM_001362	1735	14q32	Hs.49322	19	thyroxine 5'-deiodinase activity cellular_component endosome plasma membrane biological_process selenium binding integral to membrane thyroxine 5-deiodinase activity positive regulation of multicellular organism growth thyroid hormone catabolic process hormone biosynthetic process oxidation reduction
201217_x_at	0.633	10.045	2.370	3.144e-02	0.266	-3.758	RPL3	ribosomal protein L3	22	-38038832	NM_000967	6122	22q13	Hs.119598	24	RNA binding structural constituent of ribosome protein binding intracellular nucleolus cytoplasm cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
244233_at	0.163	6.713	2.369	3.145e-02	0.267	-3.758	C18orf10	chromosome 18 open reading frame 10	18	-32630031	AI470549	25941	18q12.2	Hs.695999	5	cytoplasm cytoskeleton microtubule
203302_at	-0.383	6.192	-2.369	3.145e-02	0.267	-3.758	DCK	deoxycytidine kinase	4	72078128	NM_000788	1633	4q13.3-q21.1	Hs.709	47	nucleotide binding deoxycytidine kinase activity ATP binding nucleus cytosol nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine nucleotide metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor nucleoside kinase activity	Purine metabolism Pyrimidine metabolism
244050_at	0.366	4.417	2.368	3.154e-02	0.267	-3.761	PTPLAD2	protein tyrosine phosphatase-like A domain containing 2	9	-20996364	AI804932	401494	9p21.3	Hs.716678	1	membrane integral to membrane
225416_at	-0.221	6.732	-2.368	3.154e-02	0.267	-3.761	RLIM	ring finger protein, LIM domain interacting	X	-73719537	N58188	51132	Xq13-q21	Hs.653288	9	transcription corepressor activity ubiquitin-protein ligase activity protein binding zinc ion binding negative regulation of transcription ligase activity transcriptional repressor complex modification-dependent protein catabolic process metal ion binding
237202_at	0.200	6.705	2.368	3.155e-02	0.267	-3.761	PGPEP1	pyroglutamyl-peptidase I	19	18312407	AI810572	54858	19p13.11	Hs.131776	8	cytoplasm proteolysis peptidase activity cysteine-type peptidase activity
229127_at	0.410	5.218	2.368	3.156e-02	0.267	-3.761	JAM2	junctional adhesion molecule 2	21	25933459	BF195118	58494	21q21.2	Hs.517227	21	plasma membrane plasma membrane integral to plasma membrane tight junction cell-cell adhesion cell junction	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Epithelial cell signaling in Helicobacter pylori infection
224948_at	0.220	11.648	2.367	3.159e-02	0.267	-3.762	MRPS24	mitochondrial ribosomal protein S24	7	-43872681	BF970023	64951	7p14	Hs.284286	11	molecular_function structural constituent of ribosome protein binding mitochondrion mitochondrial large ribosomal subunit mitochondrial small ribosomal subunit ribosome translation biological_process
200065_s_at	-0.293	9.894	-2.367	3.160e-02	0.267	-3.762	ARF1	ADP-ribosylation factor 1	1	226336983, 226337473	AF052179	375	1q42	Hs.286221	97	Golgi membrane nucleotide binding GTPase activity receptor signaling protein activity protein binding GTP binding intracellular Golgi apparatus cytosol cytosol plasma membrane retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane organization vesicle-mediated transport sarcomere COPI coating of Golgi vesicle	Vibrio cholerae infection
203524_s_at	0.366	7.661	2.367	3.161e-02	0.267	-3.763	MPST	mercaptopyruvate sulfurtransferase	22	35745647	NM_021126	4357	22q13.1	Hs.248267	9	thiosulfate sulfurtransferase activity cytoplasm mitochondrion sulfate transport cyanate catabolic process response to toxin transferase activity 3-mercaptopyruvate sulfurtransferase activity	Cysteine and methionine metabolism Metabolic pathways
1558148_x_at	0.276	6.099	2.367	3.161e-02	0.267	-3.763	FLJ90757	hypothetical LOC440465	17	-76617527	BG030541	440465	17q25.3	Hs.448889	3
234421_s_at	0.265	4.947	2.366	3.163e-02	0.267	-3.764	EVC	Ellis van Creveld syndrome	4	5763824	AK025394	2121	4p16	Hs.646899 Hs.670028	13	skeletal system development muscle organ development membrane integral to membrane
224376_s_at	-0.406	10.037	-2.366	3.164e-02	0.268	-3.764	C20orf24	chromosome 20 open reading frame 24	20	34667580, 34667605	AF274948	55969	20q11.23	Hs.584985	7	molecular_function protein binding cellular_component biological_process
205063_at	-0.420	5.762	-2.366	3.166e-02	0.268	-3.764	SIP1	survival of motor neuron protein interacting protein 1	14	38653238	NM_003616	8487	14q13	Hs.708127	34	spliceosome assembly spliceosomal snRNP biogenesis protein binding nucleus nucleoplasm spliceosomal complex cytoplasm cytosol RNA splicing Cajal body RNA splicing factor activity, transesterification mechanism
221936_x_at	0.235	6.108	2.366	3.168e-02	0.268	-3.765	MRPL41	mitochondrial ribosomal protein L41	9	139566129	AI090841	64975	9q34.3	Hs.44017	10	structural constituent of ribosome mitochondrion mitochondrial large ribosomal subunit ribosome translation apoptosis cell cycle
222507_s_at	-0.535	7.252	-2.366	3.168e-02	0.268	-3.765	TMEM9B	TMEM9 domain family, member B	11	-8925415	AI188389	56674	11p15.3	Hs.501853	7	signal transducer activity membrane integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
208996_s_at	-0.384	8.088	-2.366	3.169e-02	0.268	-3.765	POLR2C	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	16	56054051	BC000409	5432	16q13-q21	Hs.79402	89	nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm cytoplasm transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter protein dimerization activity	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
242230_at	-0.375	4.040	-2.365	3.170e-02	0.268	-3.765	ATXN1	ataxin 1	6	-16407321	BF438383	6310	6p23	Hs.434961 Hs.712106	65	RNA binding nucleus nucleoplasm nucleolus cytoplasm RNA processing protein C-terminus binding cell death poly(U) RNA binding adult locomotory behavior visual learning nuclear matrix negative regulation of transcription transcription repressor activity poly(G) RNA binding nuclear RNA export factor complex negative regulation of phosphorylation nuclear inclusion body identical protein binding negative regulation of insulin-like growth factor receptor signaling pathway protein self-association positive regulation of transcription from RNA polymerase II promoter nuclear export regulation of excitatory postsynaptic membrane potential
200730_s_at	-0.704	8.533	-2.365	3.171e-02	0.268	-3.766	PTP4A1	protein tyrosine phosphatase type IVA, member 1	6	64339878	BF576710	7803	6q12	Hs.227777 Hs.706850	28	protein tyrosine phosphatase activity cytoplasm early endosome endoplasmic reticulum spindle plasma membrane protein amino acid dephosphorylation cell cycle multicellular organismal development hydrolase activity
225132_at	-0.324	8.898	-2.365	3.172e-02	0.268	-3.766	FBXL3	F-box and leucine-rich repeat protein 3	13	-76477390	AI983021	26224	13q22	Hs.508284 Hs.719413	8	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm protein ubiquitination modification-dependent protein catabolic process
204412_s_at	0.273	3.262	2.365	3.173e-02	0.268	-3.766	NEFH	neurofilament, heavy polypeptide	22	28206180	NM_021076	4744	22q12.2	Hs.198760	27	microtubule cytoskeleton organization molecular_function mitochondrion neurofilament nervous system development cell death axon intermediate filament bundle assembly neurofilament cytoskeleton organization	Amyotrophic lateral sclerosis (ALS)
213554_s_at	-0.269	6.317	-2.365	3.174e-02	0.268	-3.767	CDV3	CDV3 homolog (mouse)	3	134775123, 134775990	AI928407	55573	3q22.1	Hs.518265	11	molecular_function cellular_component cytoplasm cell proliferation
203311_s_at	-0.316	7.503	-2.365	3.175e-02	0.268	-3.767	ARF6	ADP-ribosylation factor 6	14	49429485	M57763	382	14q21.3	Hs.525330 Hs.682124	86	nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis	Endocytosis Fc gamma R-mediated phagocytosis
201666_at	0.823	7.062	2.364	3.176e-02	0.268	-3.767	TIMP1	TIMP metallopeptidase inhibitor 1	X	47326633	NM_003254	7076	Xp11.3-p11.23	Hs.522632	231	enzyme inhibitor activity protein binding extracellular region proteinaceous extracellular matrix metalloendopeptidase inhibitor activity positive regulation of cell proliferation erythrocyte maturation negative regulation of membrane protein ectodomain proteolysis
235121_at	0.335	4.590	2.364	3.177e-02	0.268	-3.767	ZNF542	zinc finger protein 542	19	61571279, 61571476	BE966943	147947	19q13.43	Hs.467326	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
222998_at	-0.332	9.036	-2.364	3.178e-02	0.268	-3.767	MAF1	MAF1 homolog (S. cerevisiae)	8	145231292	AL136937	84232	8q24.3	Hs.19673	13	intracellular nucleus negative regulation of transcription from RNA polymerase III promoter transcription regulator activity regulation of transcription
203495_at	0.192	5.613	2.364	3.179e-02	0.268	-3.768	LRRC14	leucine rich repeat containing 14	8	145714198	NM_014665	9684	8q24.3	Hs.459391	3	protein binding
205638_at	0.279	2.509	2.364	3.180e-02	0.268	-3.768	BAI3	brain-specific angiogenesis inhibitor 3	6	69402352	NM_001704	577	6q12	Hs.13261	8	plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane brain-specific angiogenesis inhibitor activity
229431_at	0.400	5.397	2.364	3.180e-02	0.268	-3.768	RFXAP	regulatory factor X-associated protein	13	36291338	AI742868	5994	13q14	Hs.24422	16	transcription factor activity transcription coactivator activity nucleus	Antigen processing and presentation Primary immunodeficiency
213716_s_at	0.230	4.724	2.363	3.183e-02	0.268	-3.769	SECTM1	secreted and transmembrane 1	17	-77872188	BF939675	6398	17q25	Hs.558009	8	signal transducer activity cytokine activity extracellular region extracellular space Golgi apparatus plasma membrane immune response mesoderm development integral to membrane positive regulation of I-kappaB kinase/NF-kappaB cascade
225354_s_at	0.320	5.771	2.363	3.183e-02	0.268	-3.769	SH3BGRL2	SH3 domain binding glutamic acid-rich protein like 2	6	80397718	AL035700	83699	6q13-q15	Hs.302772	5	nucleus SH3 domain binding
217834_s_at	-0.355	6.533	-2.363	3.183e-02	0.268	-3.769	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	6	-86380411, -86380411, -86374221, -86374221, -86374221, -86374221	NM_006372	10492	6q14-q15	Hs.571177	33	nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms
211448_s_at	0.288	5.744	2.363	3.184e-02	0.268	-3.769	RGS6	regulator of G-protein signaling 6	14	71469538	AF107619	9628	14q24.3	Hs.509872	13	signal transducer activity GTPase activator activity cellular_component cytoplasm heterotrimeric G-protein complex intracellular signaling cascade regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction membrane
204805_s_at	0.324	6.896	2.363	3.185e-02	0.268	-3.770	H1FX	H1 histone family, member X	3	-130516304	NM_006026	8971	3q21.3	Hs.75307	12	nucleosome DNA binding nucleus chromosome nucleosome assembly
242341_x_at	0.225	5.416	2.363	3.187e-02	0.268	-3.770	GLYCTK	glycerate kinase	3	52296875, 52296875	AA551847	132158	3p21.1	Hs.415312	9	nucleotide binding protein binding ATP binding cytoplasm mitochondrion protein amino acid phosphorylation glycerate kinase activity transferase activity	Glycine, serine and threonine metabolism Glycerolipid metabolism Glyoxylate and dicarboxylate metabolism Metabolic pathways
208986_at	-0.222	7.508	-2.363	3.187e-02	0.268	-3.770	TCF12	transcription factor 12	15	54998124, 55298946	AL559478	6938	15q21	Hs.511504	32	DNA binding RNA polymerase II transcription factor activity protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter immune response multicellular organismal development muscle organ development transcription activator activity regulation of transcription
206345_s_at	-0.235	2.672	-2.363	3.188e-02	0.268	-3.770	PON1	paraoxonase 1	7	-94765606	NM_000446	5444	7q21.3	Hs.370995	488	aryldialkylphosphatase activity arylesterase activity phospholipid binding extracellular region extracellular space microsome lipid metabolic process response to external stimulus response to toxin positive regulation of cholesterol efflux hydrolase activity aromatic compound catabolic process positive regulation of transporter activity spherical high-density lipoprotein particle negative regulation of plasma lipoprotein oxidation protein homodimerization activity carboxylic acid catabolic process organophosphate catabolic process phosphatidylcholine metabolic process positive regulation of binding	gamma-Hexachlorocyclohexane degradation Bisphenol A degradation Metabolic pathways
1554780_a_at	-0.325	5.871	-2.362	3.188e-02	0.268	-3.771	PHTF2	putative homeodomain transcription factor 2	7	77266044, 77266044, 77307382, 77307382	BC032334	57157	7q11.23-q21	Hs.203965 Hs.601884	11	DNA binding nucleus endoplasmic reticulum regulation of transcription
237687_at	-0.549	5.915	-2.362	3.189e-02	0.268	-3.771	LOC283737	hypothetical protein LOC283737	15		H40786	283737	15q25.3	Hs.31795	1
210103_s_at	0.301	3.847	2.362	3.191e-02	0.268	-3.771	FOXA2	forkhead box A2	20	-22509641, -22509641	AB028021	3170	20p11	Hs.155651	35	ectoderm formation RNA polymerase II transcription factor activity, enhancer binding nucleus regulation of transcription, DNA-dependent pattern specification process blood coagulation anterior/posterior pattern formation regulation of specific transcription from RNA polymerase II promoter cell differentiation in hindbrain dorsal/ventral neural tube patterning lung development epithelial cell differentiation endocrine pancreas development sequence-specific DNA binding cell part negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter cell development anatomical structure formation involved in morphogenesis neuron fate specification branching morphogenesis of a tube	Maturity onset diabetes of the young
201264_at	0.289	7.014	2.362	3.191e-02	0.268	-3.771	COPE	coatomer protein complex, subunit epsilon	19	-18871322	NM_007263	11316	19p13.11	Hs.10326	28	structural molecule activity protein binding cytoplasm Golgi apparatus cytosol retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport protein transport membrane membrane organization vesicle-mediated transport COPI vesicle coat cytoplasmic vesicle COPI coating of Golgi vesicle
229001_at	-0.546	6.812	-2.362	3.192e-02	0.268	-3.771	PPP1R3E	protein phosphatase 1, regulatory (inhibitor) subunit 3E	14	-22834952	BE259127	90673	14q11.2	Hs.601513 Hs.672733	3	carbohydrate metabolic process glycogen metabolic process
225340_s_at	-0.301	7.527	-2.362	3.192e-02	0.268	-3.771	CAPRIN1	cell cycle associated protein 1	11	34029805, 34029805	BG107845	4076	11p13	Hs.471818	10	protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection
233446_at	0.301	3.362	2.362	3.192e-02	0.268	-3.772	ONECUT2	one cut homeobox 2	18	53253914	AU145336	9480	18q21.1-q21.2	Hs.194725	7	liver development regulation of cell-matrix adhesion epithelial cell development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent organ morphogenesis positive regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway endocrine pancreas development cilium assembly sequence-specific DNA binding cell fate commitment positive regulation of transcription from RNA polymerase II promoter peripheral nervous system neuron development
233954_at	-0.226	3.409	-2.362	3.193e-02	0.268	-3.772	HIATL1	hippocampus abundant transcript-like 1	9	96176653	AL110135	84641	9q22.32	Hs.555996 Hs.715500	7	transporter activity protein binding transport tetracycline:hydrogen antiporter activity tetracycline transport membrane integral to membrane response to antibiotic
203649_s_at	0.221	5.628	2.361	3.196e-02	0.269	-3.773	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	1	-20174511, -20174511	NM_000300	5320	1p35	Hs.466804	94	calcium ion binding phospholipid binding extracellular region extracellular space mitochondrion endoplasmic reticulum phospholipid metabolic process positive regulation of foam cell differentiation membrane lipid catabolic process hydrolase activity low-density lipoprotein particle remodeling somatic stem cell maintenance phosphatidic acid metabolic process calcium-dependent phospholipase A2 activity negative regulation of epithelial cell proliferation positive regulation of inflammatory response defense response to Gram-positive bacterium	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway
218078_s_at	-0.301	6.491	-2.361	3.198e-02	0.269	-3.773	ZDHHC3	zinc finger, DHHC-type containing 3	3	-44931757	NM_016598	51304	3p21.31	Hs.61430	8	Golgi apparatus zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
211562_s_at	-0.389	4.287	-2.361	3.198e-02	0.269	-3.773	LMOD1	leiomodin 1 (smooth muscle)	1	-200132206	BC001755	25802	1q32	Hs.519075	9	tropomyosin binding membrane fraction cytoplasm cytoskeleton
224685_at	0.391	7.902	2.361	3.199e-02	0.269	-3.774	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	6	167970519, 167970519, 167970519	AI675354	4301	6q27	Hs.644024 Hs.708726	51	cell-cell junction adherens junction cell adhesion signal transduction cell-cell signaling protein C-terminus binding	Adherens junction Tight junction Leukocyte transendothelial migration
213422_s_at	0.258	7.113	2.361	3.200e-02	0.269	-3.774	MXRA8	matrix-remodelling associated 8	1	-1277933	AW888223	54587	1p36.33	Hs.558570	6	membrane integral to membrane
206277_at	-0.398	7.066	-2.360	3.201e-02	0.269	-3.774	P2RY2	purinergic receptor P2Y, G-protein coupled, 2	11	72606991, 72607149	NM_002564	5029	11q13.5-q14.1	Hs.339	43	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane cellular ion homeostasis signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger purinergic nucleotide receptor activity, G-protein coupled	Neuroactive ligand-receptor interaction
223495_at	0.350	4.972	2.360	3.205e-02	0.269	-3.775	CCDC8	coiled-coil domain containing 8	19	-51605426	AI970823	83987	19q13.32	Hs.97876	4	plasma membrane
221944_at	-0.256	4.954	-2.360	3.205e-02	0.269	-3.775	FLJ42627	hypothetical LOC645644	16	2628983	N56912	645644	16p13.3	Hs.597810 Hs.677234	1
226644_at	0.335	7.357	2.359	3.208e-02	0.269	-3.776	MIB2	mindbomb homolog 2 (Drosophila)	1	1540746	BE222279	142678	1p36.33	Hs.135805 Hs.593430	14	actin binding ubiquitin-protein ligase activity signal transducer activity protein binding cytoplasm endosome Notch signaling pathway zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
242234_at	0.459	5.402	2.359	3.208e-02	0.269	-3.776	XAF1	XIAP associated factor 1	17	6599879	AI859280	54739	17p13.1	Hs.441975	27	nucleus cytoplasm mitochondrion apoptosis zinc ion binding metal ion binding
235166_at	-0.196	4.133	-2.359	3.209e-02	0.269	-3.776	ZNF148	zinc finger protein 148	3	-126427202	T08836	7707	3q21	Hs.592591	34	negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex nucleolus Golgi apparatus cellular defense response gamete generation zinc ion binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
219703_at	0.305	3.687	2.359	3.210e-02	0.269	-3.776	MNS1	meiosis-specific nuclear structural 1	15	-54508220	NM_018365	55329	15q21.3	Hs.444483	6	nucleus nuclear envelope intermediate filament meiosis
223266_at	-0.378	8.997	-2.359	3.211e-02	0.269	-3.777	STRADB	STE20-related kinase adaptor beta	2	202024636	AB038950	55437	2q33.1	Hs.652338	12	nucleotide binding protein kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation protein export from nucleus cell cycle activation of protein kinase activity
209916_at	0.301	6.714	2.359	3.213e-02	0.269	-3.777	DHTKD1	dehydrogenase E1 and transketolase domain containing 1	10	12150939	BC002477	55526	10p14	Hs.104980 Hs.711138	3	oxoglutarate dehydrogenase (succinyl-transferring) activity mitochondrion glycolysis oxidoreductase activity thiamin pyrophosphate binding oxidation reduction
206674_at	0.220	4.624	2.359	3.213e-02	0.269	-3.777	FLT3	fms-related tyrosine kinase 3	13	-27475410	NM_004119	2322	13q12	Hs.507590	213	nucleotide binding receptor activity vascular endothelial growth factor receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell proliferation membrane transferase activity hemopoiesis	Cytokine-cytokine receptor interaction Hematopoietic cell lineage Pathways in cancer Acute myeloid leukemia
211928_at	-0.244	8.973	-2.358	3.215e-02	0.269	-3.778	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	14	101500617	AB002323	1778	14q32 14q32.3-qter	Hs.649497	33	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm Golgi apparatus cytoplasmic dynein complex microtubule microtubule-based movement mitotic spindle organization ATPase activity, coupled
210659_at	0.248	5.257	2.358	3.216e-02	0.269	-3.778	CMKLR1	chemokine-like receptor 1	12	-107205951, -107205951	U79526	1240	12q24.1	Hs.197143	14	skeletal system development receptor activity G-protein coupled receptor activity chemokine receptor activity plasma membrane integral to plasma membrane chemotaxis immune response signal transduction G-protein coupled receptor protein signaling pathway
226529_at	-0.374	9.306	-2.358	3.218e-02	0.270	-3.779	TMEM106B	transmembrane protein 106B	7	12217372	BF513060	54664	7p21.3	Hs.396358	10	molecular_function cellular_component biological_process membrane integral to membrane
236123_at	0.256	3.782	2.357	3.219e-02	0.270	-3.779	ST7L	suppression of tumorigenicity 7 like	1	-112885935, -112867663	BE220209	54879	1p13.2	Hs.201921	6	membrane integral to membrane
1556181_at	0.173	5.797	2.357	3.221e-02	0.270	-3.779	hCG_20426	hypothetical protein LOC441869	1	-1343664	BC018095	441869	1p36.33	Hs.381222	3
204701_s_at	0.195	6.140	2.357	3.222e-02	0.270	-3.780	STOML1	stomatin (EPB72)-like 1	15	-72062612	NM_004809	9399	15q24-q25	Hs.194816	9	molecular_function sterol carrier activity cellular_component biological_process membrane integral to membrane
204181_s_at	-0.299	7.038	-2.357	3.223e-02	0.270	-3.780	ZBTB43	zinc finger and BTB domain containing 43	9	128607105	T90308	23099	9q33-q34	Hs.355581 Hs.718657	7	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
208909_at	0.196	12.479	2.357	3.223e-02	0.270	-3.780	UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	19	-34390006	BC000649	7386	19q12-q13.1	Hs.170107	10	iron ion binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex III transport ubiquinol-cytochrome-c reductase activity electron carrier activity membrane integral to membrane oxidoreductase activity, acting on diphenols and related substances as donors electron transport chain metal ion binding 2 iron, 2 sulfur cluster binding respiratory chain	Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease
218759_at	0.213	5.583	2.357	3.225e-02	0.270	-3.781	DVL2	dishevelled, dsh homolog 2 (Drosophila)	17	-7069384	NM_004422	1856	17p13.2	Hs.118640	25	neural tube closure signal transducer activity intracellular cytoplasm intracellular signaling cascade multicellular organismal development segment specification imaginal disc pattern formation heart development Wnt receptor signaling pathway identical protein binding	Wnt signaling pathway Notch signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma
225222_at	-0.332	6.958	-2.356	3.226e-02	0.270	-3.781	HIAT1	hippocampus abundant transcript 1	1	100276376	AI243268	64645	1p21.2	Hs.124156	5	transporter activity transport tetracycline:hydrogen antiporter activity tetracycline transport membrane integral to membrane response to antibiotic
233082_at	0.389	4.387	2.356	3.229e-02	0.270	-3.782	ZNF630	zinc finger protein 630	X	-47802510	AK000580	57232	Xp11.3-p11.1	Hs.650883	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225982_at	0.243	6.432	2.356	3.230e-02	0.270	-3.782	UBTF	upstream binding transcription factor, RNA polymerase I	17	-39637926, -39637926, -39637926	BG341575	7343	17q21.3	Hs.89781	53	DNA binding RNA polymerase I transcription factor activity protein binding nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase I promoter regulation of transcription
244675_at	0.212	3.368	2.355	3.233e-02	0.270	-3.783	RGS8	regulator of G-protein signaling 8	1	-180882414	R37101	85397	1q25	Hs.20982 Hs.458417	14	signal transducer activity negative regulation of signal transduction
228776_at	0.338	6.271	2.355	3.234e-02	0.270	-3.783	GJC1	gap junction protein, gamma 1, 45kDa	17	-40231341, -40231341	AA430014	10052	17q21.31	Hs.532593 Hs.712052	18	vasculogenesis protein binding plasma membrane connexon complex transport muscle contraction cell-cell junction assembly synaptic transmission visual perception integral to membrane cell junction cell development cardiac muscle tissue development
243880_at	-0.622	3.535	-2.355	3.234e-02	0.270	-3.783	GOSR2	golgi SNAP receptor complex member 2	17	42355484, 42355484	AW205003	9570	17q21	Hs.463278	12	Golgi membrane transporter activity endoplasmic reticulum membrane Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport membrane fusion membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
229025_s_at	0.297	9.138	2.355	3.238e-02	0.270	-3.784	IMMP1L	IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)	11	-31410524	AW008627	196294	11p13	Hs.502223	5	mitochondrion mitochondrial inner membrane proteolysis peptidase activity serine-type peptidase activity membrane
1561252_at	-0.190	3.855	-2.354	3.239e-02	0.270	-3.785	LOC648691	hypothetical LOC648691	22	21231755	BC040190	648691		Hs.623889
212377_s_at	0.348	6.158	2.354	3.240e-02	0.270	-3.785	NOTCH2	Notch homolog 2 (Drosophila)	1	-120255698	AU158495	4853	1p13-p11	Hs.487360	73	cell fate determination ligand-regulated transcription factor activity receptor activity calcium ion binding protein binding protein binding nucleus plasma membrane integral to plasma membrane regulation of transcription, DNA-dependent anti-apoptosis induction of apoptosis cell cycle arrest Notch signaling pathway multicellular organismal development nervous system development negative regulation of cell proliferation organ morphogenesis cell surface cell growth stem cell maintenance hemopoiesis cell differentiation positive regulation of Ras protein signal transduction protein heterodimerization activity regulation of developmental process	Dorso-ventral axis formation Notch signaling pathway
1559479_at	0.271	3.637	2.354	3.240e-02	0.270	-3.785	PI4K2B	phosphatidylinositol 4-kinase type 2 beta	4	24844750	BC038425	55300	4p15.2	Hs.191701	9	nucleotide binding 1-phosphatidylinositol 4-kinase activity ATP binding cytoplasm membrane kinase activity transferase activity
203257_s_at	0.231	5.685	2.354	3.241e-02	0.270	-3.785	C11orf49	chromosome 11 open reading frame 49	11	46914826, 46914826	NM_024113	79096	11p11.2	Hs.368296	11
1555722_at	0.307	3.661	2.354	3.241e-02	0.270	-3.785	SCAMPER	sphingolipid Ca2+ release mediating protein of endoplasmic reticulum			AY163814	286756			1
213618_at	0.289	3.730	2.354	3.242e-02	0.271	-3.785	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	4	-35744016	AB011152	116984	4p14	Hs.479451	9	phosphatidylinositol-3,4,5-trisphosphate binding intracellular cytoplasm signal transduction ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding	Endocytosis
225288_at	0.407	5.649	2.354	3.244e-02	0.271	-3.786	COL27A1	collagen, type XXVII, alpha 1	9	115958051	AI949136	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
219354_at	-0.254	5.446	-2.353	3.245e-02	0.271	-3.786	KLHL26	kelch-like 26 (Drosophila)	19	18608837	NM_018316	55295	19p13.11	Hs.250632	6	protein binding
203950_s_at	-0.239	6.514	-2.353	3.247e-02	0.271	-3.787	CLCN6	chloride channel 6	1	11788793, 11788793, 11788793	NM_001286	1185	1p36	Hs.193043	13	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport cell volume homeostasis signal transduction antiporter activity membrane integral to membrane chloride ion binding
207266_x_at	0.278	7.586	2.353	3.249e-02	0.271	-3.787	RBMS1	RNA binding motif, single stranded interacting protein 1	2	-160836908	NM_016837	5937	2q24.2	Hs.470412	12	DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding cellular_component nucleus DNA replication RNA processing
210944_s_at	-0.391	11.557	-2.353	3.250e-02	0.271	-3.787	CAPN3	calpain 3, (p94)	15	40427592, 40438989, 40481879, 40484268	BC003169	825	15q15.1-q21.1	Hs.143261	66	calcium-dependent cysteine-type endopeptidase activity signal transducer activity calcium ion binding intracellular cytoplasm proteolysis muscle organ development peptidase activity
223496_s_at	0.243	4.697	2.353	3.250e-02	0.271	-3.787	CCDC8	coiled-coil domain containing 8	19	-51605426	AL136609	83987	19q13.32	Hs.97876	4	plasma membrane
32069_at	-0.276	7.040	-2.353	3.250e-02	0.271	-3.788	N4BP1	NEDD4 binding protein 1	16	-47130137	AB014515	9683	16q12.1	Hs.511839	6	nucleus
227809_at	-0.446	7.147	-2.352	3.252e-02	0.271	-3.788	ZC3H6	zinc finger CCCH-type containing 6	2	112749648	AI703114	376940	2q13	Hs.190477	5	nucleic acid binding zinc ion binding metal ion binding
203140_at	-0.922	10.442	-2.352	3.253e-02	0.271	-3.788	BCL6	B-cell CLL/lymphoma 6	3	-188921858, -188921858, -188921858	NM_001706	604	3q27	Hs.478588	139	protein import into nucleus, translocation negative regulation of transcription from RNA polymerase II promoter cell morphogenesis negative regulation of cell-matrix adhesion regulation of germinal center formation negative regulation of T-helper 2 type immune response negative regulation of B cell apoptosis transcription factor activity protein binding intracellular nucleus replication fork response to DNA damage stimulus spermatogenesis protein localization zinc ion binding negative regulation of cell proliferation transcription repressor activity transcription repressor activity actin cytoskeleton organization B cell differentiation negative regulation of cell growth positive regulation of B cell proliferation chromatin DNA binding regulation of Rho GTPase activity negative regulation of mast cell cytokine production negative regulation of Rho protein signal transduction positive regulation of apoptosis negative regulation of apoptosis regulation of memory T cell differentiation sequence-specific DNA binding regulation of transcription negative regulation of cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of S phase of mitotic cell cycle metal ion binding negative regulation of isotype switching to IgE isotypes erythrocyte development regulation of inflammatory response positive regulation of cell motion
214666_x_at	-0.430	4.839	-2.352	3.254e-02	0.271	-3.789	IREB2	iron-responsive element binding protein 2	15	76517572	AI204981	3658	15q25.1	Hs.436031	28	RNA binding iron ion binding cytoplasm cytosol regulation of translation protoporphyrinogen IX biosynthetic process cellular iron ion homeostasis metabolic process post-embryonic development regulation of gene expression iron-responsive element binding erythrocyte homeostasis metal ion binding intestinal absorption 4 iron, 4 sulfur cluster binding
235201_at	-0.742	6.351	-2.352	3.255e-02	0.271	-3.789	FOXP2	forkhead box P2	7	113842287	AW167727	93986	7q31	Hs.656280	50	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding caudate nucleus development putamen development protein homodimerization activity sequence-specific DNA binding metal ion binding
224622_at	-0.262	7.355	-2.352	3.255e-02	0.271	-3.789	TBC1D14	TBC1 domain family, member 14	4	6962071, 6962395, 7039789	AB037743	57533	4p16.1	Hs.518611	7	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
1562988_at	-0.192	3.259	-2.352	3.255e-02	0.271	-3.789	ZNF397OS	zinc finger protein 397 opposite strand	18	-31086816	AF373035	100101467	18q12.2	Hs.464896	3	transcription factor activity intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
230351_at	0.343	5.499	2.352	3.256e-02	0.271	-3.789	LOC283481	hypothetical protein LOC283481	13		AW070248	283481	13q33.1	Hs.646604	2
203554_x_at	0.351	5.787	2.351	3.258e-02	0.271	-3.790	PTTG1	pituitary tumor-transforming 1	5	159781442	NM_004219	9232	5q35.1	Hs.350966	88	transcription factor activity cysteine-type endopeptidase inhibitor activity protein binding nucleus cytoplasm cytosol DNA repair transcription from RNA polymerase II promoter response to DNA damage stimulus cell cycle chromosome segregation mitosis spermatogenesis SH3 domain binding chromosome organization cell division	Cell cycle
210955_at	0.268	4.577	2.351	3.260e-02	0.271	-3.790	CASP10	caspase 10, apoptosis-related cysteine peptidase	2	201755865, 201755865	U86214	843	2q33-q34	Hs.5353	72	cysteine-type endopeptidase activity proteolysis peptidase activity induction of apoptosis by extracellular signals identical protein binding regulation of apoptosis	Apoptosis RIG-I-like receptor signaling pathway
223084_s_at	-0.415	8.721	-2.351	3.260e-02	0.271	-3.790	CCNDBP1	cyclin D-type binding-protein 1	15	41264757, 41265429	AF246144	23582	15q14-q15	Hs.36794 Hs.368642 Hs.688009	19	protein binding nucleus cytoplasm cell cycle
218446_s_at	-0.362	6.287	-2.350	3.264e-02	0.271	-3.791	FAM18B	family with sequence similarity 18, member B	17	18625306	NM_016078	51030	17p11.2	Hs.87295	3	membrane integral to membrane
220451_s_at	0.275	5.804	2.350	3.265e-02	0.271	-3.792	BIRC7	baculoviral IAP repeat-containing 7	20	61337720	NM_022161	79444	20q13.3	Hs.256126	36	intracellular nucleus cytoplasm DNA fragmentation involved in apoptosis apoptosis anti-apoptosis activation of JUN kinase activity zinc ion binding enzyme binding metal ion binding
204462_s_at	0.231	4.474	2.350	3.266e-02	0.271	-3.792	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)	X	73557809	NM_006517	6567	Xq13.2	Hs.75317	28	transporter activity membrane fraction plasma membrane integral to plasma membrane transport monocarboxylic acid transmembrane transporter activity symporter activity monocarboxylic acid transport
235313_at	-0.675	11.573	-2.350	3.269e-02	0.271	-3.793	NRAP	nebulin-related anchoring protein	10	-115338572	AA195854	4892	10q24-q26	Hs.268788	14	actin binding actin binding protein binding fascia adherens muscle tendon junction biological_process zinc ion binding metal ion binding muscle alpha-actinin binding
1556607_at	0.271	4.086	2.350	3.269e-02	0.271	-3.793	EHD4	EH-domain containing 4	15	-39978932	AK074621	30844	15q11.1	Hs.143703	11	nucleotide binding nucleic acid binding GTPase activity calcium ion binding protein binding ATP binding GTP binding nucleus endosome endoplasmic reticulum membrane	Endocytosis
208850_s_at	0.323	5.513	2.349	3.270e-02	0.271	-3.793	THY1	Thy-1 cell surface antigen	11	-118793865	AL558479	7070	11q22.3-q23	Hs.644697 Hs.719101	45	angiogenesis Rho GTPase activator activity integrin binding protein binding endoplasmic reticulum cytosol plasma membrane integral to plasma membrane negative regulation of protein kinase activity cytoskeleton organization external side of plasma membrane cell-cell adhesion negative regulation of cell migration dendrite growth cone anchored to membrane anchored to external side of plasma membrane GPI anchor binding positive regulation of GTPase activity membrane raft retinal cone cell development focal adhesion formation negative regulation of axonogenesis negative regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of release of sequestered calcium ion into cytosol	Leukocyte transendothelial migration
215265_at	0.209	6.065	2.349	3.271e-02	0.271	-3.793	EMX1	empty spiracles homeobox 1	2	72998111	BF515060	2016	2p14-p13	Hs.516090	9	transcription factor activity nucleus regulation of transcription, DNA-dependent brain development post-embryonic development cerebral cortex development neuron differentiation response to drug sequence-specific DNA binding
209529_at	0.275	4.155	2.349	3.271e-02	0.271	-3.793	PPAP2C	phosphatidic acid phosphatase type 2C	19	-232043, -232043	AF047760	8612	19p13	Hs.465506	10	phosphoprotein phosphatase activity cytosol phosphatidate phosphatase activity phosphatidate phosphatase activity membrane integral to membrane hydrolase activity	Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis
1554703_at	0.270	4.650	2.349	3.273e-02	0.271	-3.794	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10	8	1759555	BC040474	9639	8p23	Hs.98594	9	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
201434_at	-0.234	8.388	-2.349	3.274e-02	0.271	-3.794	TTC1	tetratricopeptide repeat domain 1	5	159368757	NM_003314	7265	5q33.3	Hs.519718	10	protein folding unfolded protein binding
209030_s_at	0.451	6.414	2.349	3.274e-02	0.272	-3.794	CADM1	cell adhesion molecule 1	11	-114549554	NM_014333	23705	11q23.2	Hs.370510	50	T cell mediated cytotoxicity receptor binding receptor binding plasma membrane cell-cell junction apoptosis immune response cell adhesion homophilic cell adhesion heterophilic cell adhesion multicellular organismal development spermatogenesis protein C-terminus binding cell recognition cell recognition integral to membrane basolateral plasma membrane cell differentiation PDZ domain binding susceptibility to natural killer cell mediated cytotoxicity susceptibility to natural killer cell mediated cytotoxicity protein homodimerization activity positive regulation of cytokine secretion activated T cell proliferation detection of stimulus detection of stimulus	Cell adhesion molecules (CAMs)
1569781_at	-0.200	3.312	-2.349	3.275e-02	0.272	-3.794	LOC285423	hypothetical LOC285423	4		BC031092	285423	4q31.23	Hs.591689
203931_s_at	0.310	8.923	2.349	3.276e-02	0.272	-3.795	MRPL12	mitochondrial ribosomal protein L12	17	77280811	NM_002949	6182	17q25	Hs.109059	11	RNA binding structural constituent of ribosome protein binding intracellular mitochondrion mitochondrial large ribosomal subunit ribosome transcription from mitochondrial promoter translation positive regulation of transcription, DNA-dependent
218469_at	-0.796	4.026	-2.348	3.277e-02	0.272	-3.795	GREM1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	15	30797496	NM_013372	26585	15q13-q15	Hs.40098	28	cytokine activity protein binding extracellular region extracellular space multicellular organismal development nervous system development
218356_at	-0.250	7.382	-2.348	3.279e-02	0.272	-3.795	FTSJ2	FtsJ homolog 2 (E. coli)	7	-2240451	NM_013393	29960	7p22	Hs.279877	4	nucleic acid binding nucleus nucleolus rRNA processing RNA methyltransferase activity transferase activity rRNA methylation methylation
219984_s_at	-0.375	8.399	-2.348	3.279e-02	0.272	-3.795	HRASLS	HRAS-like suppressor	3	194441611	NM_020386	57110	3q29	Hs.36761	4	nuclear envelope lumen cytoplasm
204547_at	-0.647	8.571	-2.348	3.279e-02	0.272	-3.795	RAB40B	RAB40B, member RAS oncogene family	17	-78208232	NM_006822	10966	17q25.3	Hs.484068	5	nucleotide binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport modification-dependent protein catabolic process
216347_s_at	0.217	6.265	2.347	3.284e-02	0.272	-3.797	PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	14	-103269840	AK023188	23368	14q32.33	Hs.709297	13	protein binding nucleus cytoplasm apoptosis induction of apoptosis negative regulation of cell cycle
233158_at	0.273	5.039	2.347	3.285e-02	0.272	-3.797	KRT82	keratin 82	12	-51074001	AI082251	3888	12q13	Hs.134640	5	protein binding cellular_component biological_process structural constituent of epidermis keratin filament
220907_at	0.156	4.761	2.347	3.285e-02	0.272	-3.797	GPR110	G protein-coupled receptor 110	6	-47095580, -47075771	NM_025048	266977	6p12.3	Hs.256897	11	G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane
223289_s_at	-0.742	7.232	-2.347	3.288e-02	0.272	-3.798	USP38	ubiquitin specific peptidase 38	4	144325519	AF211481	84640		Hs.480848	7	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
201210_at	-0.425	9.919	-2.347	3.288e-02	0.272	-3.798	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	X	41077594	NM_001356	1654	Xp11.3-p11.23	Hs.719127	34	nucleotide binding DNA binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus cytoplasm plasma membrane nuclear speck hydrolase activity interspecies interaction between organisms	RIG-I-like receptor signaling pathway
235245_at	0.249	5.176	2.346	3.289e-02	0.272	-3.798	TMEM92	transmembrane protein 92	17	45706831	AI990471	162461	17q21.33	Hs.224630	4	membrane integral to membrane
207532_at	0.255	5.294	2.346	3.290e-02	0.272	-3.798	CRYGD	crystallin, gamma D	2	-208694575	NM_006891	1421	2q33-q35	Hs.546247	49	structural constituent of eye lens protein binding soluble fraction visual perception cellular response to reactive oxygen species response to stimulus
223408_s_at	-0.264	6.351	-2.346	3.290e-02	0.272	-3.798	FOXK2	forkhead box K2	17	78070882	N49941	3607	17q25	Hs.591140	11	magnesium ion binding transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding
204931_at	0.314	3.536	2.346	3.291e-02	0.272	-3.799	TCF21	transcription factor 21	6	134251951, 134251952	NM_003206	6943	6pter-qter	Hs.78061	16	branching involved in ureteric bud morphogenesis DNA binding protein binding nucleus mesoderm development sex differentiation organ morphogenesis transcription regulator activity regulation of transcription
212039_x_at	0.604	10.236	2.346	3.291e-02	0.272	-3.799	RPL3	ribosomal protein L3	22	-38038832	BG339228	6122	22q13	Hs.119598	24	RNA binding structural constituent of ribosome protein binding intracellular nucleolus cytoplasm cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
233557_s_at	-0.192	5.174	-2.346	3.291e-02	0.272	-3.799	MON1B	MON1 homolog B (yeast)	16	75782336	AK023374	22879	16q23.1	Hs.513743	6
228393_s_at	0.329	8.085	2.346	3.291e-02	0.272	-3.799	ZNF302	zinc finger protein 302	19	39860406	BF508739	55900	19q13.11	Hs.436350	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
227476_at	-0.314	6.861	-2.346	3.292e-02	0.272	-3.799	LPGAT1	lysophosphatidylglycerol acyltransferase 1	1	-209983422	AW576195	9926	1q32	Hs.497674	6	molecular_function cytoplasm endoplasmic reticulum metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity
212128_s_at	-0.275	6.317	-2.346	3.292e-02	0.272	-3.799	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	3	49482568	AW411370	1605	3p21	Hs.707131 Hs.76111	56	morphogenesis of an epithelial sheet calcium ion binding protein binding extracellular region basement membrane extracellular space membrane fraction cytoplasm integral to plasma membrane protein complex assembly muscle contraction actin cytoskeleton dystroglycan complex sarcolemma membrane raft	ECM-receptor interaction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
205331_s_at	0.198	7.232	2.346	3.294e-02	0.272	-3.800	REEP2	receptor accessory protein 2	5	137802674	NM_016606	51308	5q31	Hs.416090	10	membrane integral to membrane
217767_at	0.431	7.580	2.346	3.295e-02	0.272	-3.800	C3	complement component 3	19	-6628845	NM_000064	718	19p13.3-p13.2	Hs.529053	215	positive regulation of type IIa hypersensitivity endopeptidase inhibitor activity receptor binding extracellular region extracellular region extracellular space inflammatory response complement activation, alternative pathway complement activation, alternative pathway complement activation, classical pathway signal transduction G-protein coupled receptor protein signaling pathway positive regulation of phagocytosis	Complement and coagulation cascades Systemic lupus erythematosus
203179_at	0.255	7.076	2.345	3.300e-02	0.272	-3.801	GALT	galactose-1-phosphate uridylyltransferase	9	34636634	NM_000155	2592	9p13	Hs.522090	72	iron ion binding cytosol carbohydrate metabolic process galactose metabolic process UDP-glucose:hexose-1-phosphate uridylyltransferase activity UDP-glucose:hexose-1-phosphate uridylyltransferase activity zinc ion binding transferase activity nucleotidyltransferase activity metal ion binding	Galactose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
233564_s_at	0.286	4.917	2.345	3.300e-02	0.272	-3.801	CDADC1	cytidine and dCMP deaminase domain containing 1	13	48720103	AL138875	81602	13q14.2	Hs.388220	2	zinc ion binding hydrolase activity metal ion binding
203781_at	0.205	11.411	2.345	3.301e-02	0.272	-3.801	MRPL33	mitochondrial ribosomal protein L33	2	27848087	NM_004891	9553	2p21	Hs.515879	8	structural constituent of ribosome intracellular mitochondrion ribosome translation
226919_at	-0.254	6.544	-2.344	3.302e-02	0.272	-3.802	LYRM2	LYR motif containing 2	6	-90398663	AA447709	57226	6q14.2-q16.1	Hs.177275	5
235450_at	-0.556	4.111	-2.344	3.302e-02	0.272	-3.802	FBXL4	F-box and leucine-rich repeat protein 4	6	-99428321	BF571480	26235	6q16.1-q16.3	Hs.536850	6	ubiquitin ligase complex nucleus cytoplasm ubiquitin-dependent protein catabolic process
228253_at	0.259	4.842	2.344	3.303e-02	0.272	-3.802	LOXL3	lysyl oxidase-like 3	2	-74613453	AI917716	84695	2p13	Hs.469045	10	protein-lysine 6-oxidase activity scavenger receptor activity copper ion binding extracellular region extracellular space biological_process membrane oxidoreductase activity metal ion binding oxidation reduction
223709_s_at	0.277	4.490	2.344	3.304e-02	0.272	-3.802	WNT10A	wingless-type MMTV integration site family, member 10A	2	219453498	AY009400	80326	2q35	Hs.121540	9	signal transducer activity extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development	Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma
206220_s_at	0.241	6.203	2.344	3.305e-02	0.272	-3.802	RASA3	RAS p21 protein activator 3	13	-113765295	NM_007368	22821	13q34	Hs.593075	14	GTPase activator activity intracellular plasma membrane intracellular signaling cascade zinc ion binding calcium-release channel activity intrinsic to internal side of plasma membrane metal ion binding regulation of small GTPase mediated signal transduction
204017_at	0.440	4.302	2.344	3.306e-02	0.272	-3.803	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	22	37194028, 37194028	NM_006855	11015	22q13.1	Hs.528305	8	receptor activity endoplasmic reticulum protein retention in ER lumen protein transport membrane integral to membrane vesicle-mediated transport ER retention sequence binding	Vibrio cholerae infection
226084_at	0.383	5.443	2.344	3.307e-02	0.273	-3.803	MAP1B	microtubule-associated protein 1B	5	71438873	AA554833	4131	5q13	Hs.335079	34	microtubule bundle formation actin binding structural molecule activity protein binding cytosol microtubule microtubule associated complex negative regulation of microtubule depolymerization dendrite development
219639_x_at	-0.227	7.633	-2.344	3.308e-02	0.273	-3.803	PARP6	poly (ADP-ribose) polymerase family, member 6	15	-70320575	NM_020213	56965	15q23	Hs.270244	5	NAD+ ADP-ribosyltransferase activity nucleus transferase activity, transferring glycosyl groups
219846_at	-0.206	4.459	-2.344	3.308e-02	0.273	-3.803	GON4L	gon-4-like (C. elegans)	1	-154001199, -153986133	NM_025174	54856	1q22	Hs.656361	11	DNA binding nucleus cytoplasm regulation of transcription, DNA-dependent
224645_at	-0.283	7.017	-2.343	3.308e-02	0.273	-3.803	EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2	10	71833866	BG106477	1979	10q21-q22	Hs.621200 Hs.695953 Hs.705686	22	protein binding eukaryotic initiation factor 4E binding insulin receptor signaling pathway cAMP-mediated signaling negative regulation of translational initiation
222924_at	-0.525	7.669	-2.343	3.309e-02	0.273	-3.804	SLMAP	sarcolemma associated protein	3	57718213	BF526855	7871	3p21.2-p14.3	Hs.476432	11	smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding
213315_x_at	0.292	8.002	2.343	3.312e-02	0.273	-3.804	CXorf40A	chromosome X open reading frame 40A	X	148430462	L43577	91966	Xq28	Hs.534641	11	protein binding
207573_x_at	0.225	11.545	2.343	3.314e-02	0.273	-3.805	ATP5L	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G	11	117777313	NM_006476	10632	11q23.3	Hs.486360	15	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) protein binding mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity	Oxidative phosphorylation Metabolic pathways
226625_at	0.336	7.341	2.343	3.314e-02	0.273	-3.805	TGFBR3	transforming growth factor, beta receptor III	1	-91918489	AW193698	7049	1p33-p32	Hs.482390	60	liver development type II transforming growth factor beta receptor binding extracellular region extracellular space plasma membrane integral to plasma membrane immune response transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway protein kinase cascade heparin binding external side of plasma membrane coreceptor activity cell growth cell migration PDZ domain binding BMP signaling pathway response to follicle-stimulating hormone stimulus inhibin-betaglycan-ActRII complex response to prostaglandin E stimulus response to luteinizing hormone stimulus intracellular membrane-bounded organelle SMAD binding transforming growth factor beta binding negative regulation of epithelial cell proliferation negative regulation of cell motion ventricular cardiac muscle morphogenesis palate development cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition definitive erythrocyte differentiation heart trabecula formation pathway-restricted SMAD protein phosphorylation transforming growth factor beta receptor activity, type III
219377_at	-0.298	6.182	-2.342	3.317e-02	0.273	-3.806	FAM59A	family with sequence similarity 59, member A	18	-28101474	NM_022751	64762	18q12.1	Hs.444314	7
211503_s_at	-0.259	8.042	-2.342	3.318e-02	0.273	-3.806	RAB14	RAB14, member RAS oncogene family	9	-122980236	AF112206	51552	9q32-q34.11	Hs.371563 Hs.713585	19	nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm
232256_s_at	0.214	2.942	2.342	3.318e-02	0.273	-3.806	LOC401321	hypothetical LOC401321	7		AF143329	401321	7p14.3	Hs.627604	1
1556555_at	0.223	4.907	2.342	3.318e-02	0.273	-3.806	LOC100129461	hypothetical protein LOC100129461	6		AI473891	100129461	6p25.1	Hs.131700
1554483_at	0.244	6.345	2.341	3.321e-02	0.273	-3.807	TMEM37	transmembrane protein 37	2	119905915	AF361356	140738	2q14.2	Hs.26216	3	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane
214673_s_at	0.207	5.463	2.341	3.322e-02	0.273	-3.807	HUWE1	HECT, UBA and WWE domain containing 1	X	-53575796	AU140931	10075	Xp11.22	Hs.136905	28	protein polyubiquitination DNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm protein modification process histone ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation	Ubiquitin mediated proteolysis
205763_s_at	-0.366	6.085	-2.341	3.325e-02	0.273	-3.808	DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	2	118288724	NM_006773	8886	2q14.1	Hs.363492	6	nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding hydrolase activity
58367_s_at	0.248	7.174	2.341	3.325e-02	0.273	-3.808	ZNF419	zinc finger protein 419	19	62690890	AA429615	79744	19q13.43	Hs.710285	6	DNA binding intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1554708_s_at	0.236	4.109	2.341	3.325e-02	0.273	-3.808	C9orf68	chromosome 9 open reading frame 68	9	-4588315	BC034293	55064	9p24.2-p24.1	Hs.179615	5
208395_s_at	0.196	5.422	2.341	3.326e-02	0.273	-3.808	URB1	URB1 ribosome biogenesis 1 homolog (S. cerevisiae)	21	-32605200	NM_014825	9875	21q22.11	Hs.473611	9	molecular_function protein binding nucleus nucleolus biological_process
203565_s_at	-0.283	7.850	-2.341	3.326e-02	0.273	-3.808	MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	14	60271222	NM_002431	4331	14q23	Hs.509523	66	regulation of cyclin-dependent protein kinase activity nucleotide-excision repair, DNA damage removal nucleus nucleoplasm cytoplasm DNA repair transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter protein complex assembly apoptosis cell cycle adult heart development zinc ion binding cell proliferation ventricular system development multicellular organismal metabolic process positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter metal ion binding protein N-terminus binding regulation of catalytic activity response to calcium ion	Nucleotide excision repair
228570_at	0.338	4.354	2.341	3.327e-02	0.273	-3.808	BTBD11	BTB (POZ) domain containing 11	12	106236326, 106498763	BF510581	121551	12q23.3	Hs.271272	2	DNA binding protein binding membrane integral to membrane
205786_s_at	0.550	4.842	2.341	3.327e-02	0.273	-3.808	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	16	31178788, 31178788	NM_000632	3684	16p11.2	Hs.172631	145	magnesium ion binding glycoprotein binding receptor activity calcium ion binding cell adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane protein heterodimerization activity	Cell adhesion molecules (CAMs) Hematopoietic cell lineage Leukocyte transendothelial migration Regulation of actin cytoskeleton
222874_s_at	0.357	5.607	2.340	3.328e-02	0.273	-3.809	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	8	1699276	AF123757	2055	8p23	Hs.127675	15	age-dependent response to oxidative stress endoplasmic reticulum ER-Golgi intermediate compartment phospholipid metabolic process lipid transport mitochondrial membrane organization lysosome organization nervous system development adult walking behavior cholesterol metabolic process associative learning regulation of cell size lipid biosynthetic process membrane integral to membrane spinal cord motor neuron differentiation social behavior negative regulation of apoptosis cellular protein catabolic process cellular macromolecule catabolic process photoreceptor cell maintenance negative regulation of proteolysis ceramide biosynthetic process musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate uptake during transmission of nerve impulse retina development in camera-type eye neurofilament cytoskeleton organization
204344_s_at	-0.470	6.373	-2.340	3.328e-02	0.273	-3.809	SEC23A	Sec23 homolog A (S. cerevisiae)	14	-38570873	NM_006364	10484	14q21.1	Hs.272927	18	Golgi membrane protein binding endoplasmic reticulum Golgi apparatus cytosol intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport zinc ion binding membrane membrane organization vesicle-mediated transport COPII vesicle coat perinuclear region of cytoplasm
203657_s_at	-0.320	7.547	-2.340	3.329e-02	0.273	-3.809	CTSF	cathepsin F	11	-66087510	NM_003793	8722	11q13	Hs.11590	12	cysteine-type endopeptidase activity lysosome proteolysis peptidase activity	Lysosome
218525_s_at	-0.239	7.043	-2.340	3.330e-02	0.273	-3.809	HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	10	102285630	NM_017902	55662	10q24	Hs.500788	30	peptide-aspartate beta-dioxygenase activity iron ion binding protein binding nucleus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction
1552946_at	0.227	3.408	2.340	3.330e-02	0.273	-3.809	ZNF114	zinc finger protein 114	19	53466465	NM_153608	163071	19q13.33	Hs.511883	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
229100_s_at	-0.174	6.465	-2.340	3.331e-02	0.273	-3.809	TIMM22	translocase of inner mitochondrial membrane 22 homolog (yeast)	17	847106	H87708	29928	17p13	Hs.719296	8	protein binding mitochondrion mitochondrial inner membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport
222541_at	-0.280	5.479	-2.340	3.332e-02	0.273	-3.810	RSF1	remodeling and spacing factor 1	11	-77054921	AA173588	51773	11q14.1	Hs.420229	19	nucleus nucleosome assembly chromatin remodeling transcription initiation zinc ion binding transcription activator activity transcription repressor activity nucleosome positioning ATPase activity RSF complex histone binding negative regulation of DNA binding regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding positive regulation of viral transcription
221482_s_at	-0.343	11.038	-2.340	3.332e-02	0.273	-3.810	ARPP19	cAMP-regulated phosphoprotein, 19kDa	15	-50626723	BC003418	10776	15q21.2	Hs.512908	10	receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import
208159_x_at	0.415	6.452	2.340	3.333e-02	0.273	-3.810	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)	12	31118045	NM_004399	1663	12p11	Hs.443960	13	mitotic sister chromatid segregation S phase of mitotic cell cycle G2/M transition of mitotic cell cycle nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP binding nucleus nucleolus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle positive regulation of cell proliferation hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
202085_at	-0.414	6.619	-2.339	3.336e-02	0.274	-3.811	TJP2	tight junction protein 2 (zona occludens 2)	9	70978908	NM_004817	9414	9q13-q21	Hs.50382	49	guanylate kinase activity protein binding nucleus cytoplasm plasma membrane adherens junction tight junction cell junction	Tight junction Vibrio cholerae infection
223280_x_at	0.355	5.958	2.339	3.337e-02	0.274	-3.811	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	11	-59696546, -59695655	AF253977	64231	11q12.1	Hs.523702	5	receptor activity signal transduction membrane integral to membrane
204232_at	0.410	5.783	2.339	3.338e-02	0.274	-3.811	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	1	159451710	NM_004106	2207	1q23	Hs.433300	29	positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity positive regulation of type I hypersensitivity Fc receptor mediated stimulatory signaling pathway transmembrane receptor activity protein binding plasma membrane plasma membrane integral to plasma membrane phagocytosis, engulfment cell surface receptor linked signal transduction external side of plasma membrane immunoglobulin mediated immune response IgE receptor activity IgG binding antigen processing and presentation of exogenous peptide antigen via MHC class II neutrophil chemotaxis positive regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of mast cell cytokine production Fc-epsilon receptor I complex negative regulation of mast cell apoptosis antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium positive regulation of mast cell degranulation mast cell activation positive regulation of phagocytosis positive regulation of immune response	Natural killer cell mediated cytotoxicity Fc epsilon RI signaling pathway Asthma
217776_at	0.245	7.278	2.339	3.339e-02	0.274	-3.812	RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	14	-67213270	AF167438	51109	14q24.1	Hs.226007	14	retinol dehydrogenase activity binding intracellular endoplasmic reticulum membrane integral to membrane oxidoreductase activity retinol metabolic process oxidation reduction	Retinol metabolism Metabolic pathways
202227_s_at	-0.345	7.852	-2.339	3.339e-02	0.274	-3.812	BRD8	bromodomain containing 8	5	-137520471, -137503357	NM_006696	10902	5q31	Hs.519337	19	transcription factor activity thyroid hormone receptor activity nucleus nucleolus mitochondrion regulation of transcription from RNA polymerase II promoter cell surface receptor linked signal transduction chromatin modification NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation
214785_at	-0.564	5.380	-2.339	3.341e-02	0.274	-3.812	VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)	9	78982180, 78982180, 78982180	AB023203	23230	9q21	Hs.459790 Hs.662256	16	protein binding intracellular Golgi to endosome transport protein localization protein transport
222357_at	-0.433	6.839	-2.338	3.344e-02	0.274	-3.813	ZBTB20	zinc finger and BTB domain containing 20	3	-115540212	AW974823	26137	3q13.2	Hs.655108	13	DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
212902_at	-0.267	3.734	-2.338	3.347e-02	0.274	-3.814	SEC24A	SEC24 family, member A (S. cerevisiae)	5	134012377	BE645231	10802	5q31.1	Hs.595540	9	Golgi membrane molecular_function protein binding cytoplasm endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport zinc ion binding membrane membrane organization vesicle-mediated transport COPII vesicle coat perinuclear region of cytoplasm
229023_at	0.252	4.085	2.337	3.350e-02	0.274	-3.815	SFT2D3	SFT2 domain containing 3	2	128175066	BF590323	84826	2q14.3	Hs.345849 Hs.700855	4	protein transport membrane integral to membrane
212587_s_at	0.415	4.670	2.337	3.350e-02	0.274	-3.815	PTPRC	protein tyrosine phosphatase, receptor type, C	1	196874759, 196874759	AI809341	5788	1q31-q32	Hs.654514	174	negative regulation of T cell mediated cytotoxicity negative regulation of cytokine-mediated signaling pathway immunoglobulin biosynthetic process transmembrane receptor protein tyrosine phosphatase activity protein binding plasma membrane integral to plasma membrane focal adhesion negative regulation of protein kinase activity negative regulation of protein kinase activity protein amino acid dephosphorylation cell surface receptor linked signal transduction hydrolase activity protein kinase binding T cell differentiation positive regulation of B cell proliferation regulation of S phase positive regulation of T cell proliferation positive regulation of protein kinase activity T cell receptor signaling pathway B cell receptor signaling pathway positive regulation of antigen receptor-mediated signaling pathway release of sequestered calcium ion into cytosol defense response to virus regulation of cell cycle	Cell adhesion molecules (CAMs) T cell receptor signaling pathway Fc gamma R-mediated phagocytosis Primary immunodeficiency
215283_at	-0.306	6.831	-2.336	3.355e-02	0.275	-3.816	LOC339290	hypothetical LOC339290	18	5228098	U79248	339290	18p11.31	Hs.643553 Hs.700799	4
207685_at	0.207	5.628	2.336	3.357e-02	0.275	-3.816	CRYBB3	crystallin, beta B3	22	23925824	NM_004076	1417	22q11.2-q12.1 22q11.23	Hs.533022	12	structural constituent of eye lens protein binding visual perception
242070_at	0.205	3.143	2.336	3.358e-02	0.275	-3.817	LOC728485	hypothetical protein LOC728485	19		AI014470	728485	19q13.12	Hs.157101	2
202894_at	0.244	6.121	2.336	3.358e-02	0.275	-3.817	EPHB4	EPH receptor B4	7	-100238122	NM_004444	2050	7q22	Hs.437008	54	nucleotide binding receptor activity ephrin receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway cell proliferation organ morphogenesis cell surface membrane transferase activity regulation of angiogenesis	Axon guidance
201376_s_at	-0.235	6.523	-2.336	3.359e-02	0.275	-3.817	HNRNPF	heterogeneous nuclear ribonucleoprotein F	10	-43201070, -43201070, -43201070, -43201070, -43201070, -43201070	AI591354	3185	10q11.21-q11.22	Hs.712955 Hs.808	30	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm heterogeneous nuclear ribonucleoprotein complex regulation of RNA splicing
219069_at	-0.380	6.249	-2.336	3.359e-02	0.275	-3.817	ANKRD49	ankyrin repeat domain 49	11	93866800	NM_017704	54851	11q21	Hs.29052	5
237646_x_at	0.293	5.636	2.335	3.361e-02	0.275	-3.817	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	1	-6448738, -6448738, -6448738, -6448738, -6448738	H83855	57449	1p36.31	Hs.284232 Hs.619982	7	signal transducer activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm cell death regulation of Rho protein signal transduction positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm
226509_at	-0.466	6.918	-2.335	3.361e-02	0.275	-3.817	ZNF641	zinc finger protein 641	12	-47022178	AV700302	121274	12q13.11	Hs.23492	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
202869_at	0.373	5.510	2.335	3.362e-02	0.275	-3.818	OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	12	111829121, 111829121	NM_016816	4938	12q24.1	Hs.524760	44	nucleotide binding RNA binding ATP binding nucleus cytoplasm mitochondrion endoplasmic reticulum microsome nucleobase, nucleoside, nucleotide and nucleic acid metabolic process immune response transferase activity nucleotidyltransferase activity
228720_at	0.197	5.228	2.335	3.362e-02	0.275	-3.818	SORCS2	sortilin-related VPS10 domain containing receptor 2	4	7245274	AB037750	57537	4p16.1	Hs.479099	6	protein binding neuropeptide signaling pathway neuropeptide receptor activity membrane integral to membrane
237635_at	0.195	4.337	2.335	3.363e-02	0.275	-3.818	LOC100128164	four and a half LIM domains 1 pseudogene	3	-171154709, -171144467	AI075162	100128164	3q26.2	Hs.633070 Hs.716524	1
226752_at	-0.294	8.660	-2.335	3.366e-02	0.275	-3.819	FAM174A	family with sequence similarity 174, member A	5	99899022	AI816071	345757	5q21.1	Hs.716557	3	membrane integral to membrane
228847_at	0.420	5.229	2.334	3.368e-02	0.275	-3.819	EXOC3	exocyst complex component 3	5	496333	W69265	11336	5p15.33	Hs.481464	15	exocytosis protein transport	Tight junction
228855_at	0.319	6.491	2.334	3.369e-02	0.275	-3.820	NUDT7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	16	76313911, 76313911	AI927964	283927	16q23.1	Hs.719356	2	magnesium ion binding peroxisome nucleoside diphosphate metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides manganese ion binding
218984_at	-0.288	6.570	-2.334	3.372e-02	0.275	-3.820	PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	7	-104884195	NM_019042	54517	7q22.3	Hs.520619	5	pseudouridine synthesis RNA binding tRNA processing pseudouridine synthase activity isomerase activity
1558356_at	-0.571	4.756	-2.334	3.373e-02	0.275	-3.821	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	15	-68733946, -68733946	AW081879	55075	15q22-q24	Hs.108049	12	molecular_function protein binding extracellular region membrane fraction soluble fraction nucleus nuclear envelope cytoplasm cytosol cytoskeleton DNA damage response, signal transduction resulting in induction of apoptosis induction of apoptosis by oxidative stress response to UV viral reproduction positive regulation of protein import into nucleus negative regulation of NF-kappaB import into nucleus positive regulation of apoptosis positive regulation of caspase activity apoptosome perinuclear region of cytoplasm negative regulation of inflammatory response
203362_s_at	-0.372	4.300	-2.333	3.374e-02	0.275	-3.821	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	4	-121200024	NM_002358	4085	4q27	Hs.591697	92	condensed chromosome kinetochore protein binding nucleus nuclear pore cytoplasm cytosol cytosol cell cycle mitosis mitotic cell cycle checkpoint anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process protein homodimerization activity perinuclear region of cytoplasm cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle
212236_x_at	0.212	6.113	2.333	3.375e-02	0.275	-3.821	KRT17	keratin 17	17	-37029217	Z19574	3872	17q12-q21	Hs.2785	39	structural constituent of cytoskeleton protein binding nucleus nucleolus cytoplasm cytoskeleton intermediate filament epidermis development
1560396_at	0.283	3.412	2.333	3.377e-02	0.275	-3.821	KLHL6	kelch-like 6 (Drosophila)	3	-184688012	AK097976	89857		Hs.659147	6	protein binding
212195_at	-0.254	9.126	-2.333	3.377e-02	0.275	-3.821	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	5	-55272450	AL049265	3572	5q11	Hs.532082	124	positive regulation of acute inflammatory response positive regulation of adaptive immune response receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity interleukin-6 receptor activity interleukin-11 receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity receptor binding ciliary neurotrophic factor receptor binding extracellular region plasma membrane interleukin-6 receptor complex oncostatin-M receptor complex glycogen metabolic process signal transduction positive regulation of cell proliferation regulation of Notch signaling pathway external side of plasma membrane positive regulation vascular endothelial growth factor production positive regulation of cardiac muscle hypertrophy integral to membrane response to cytokine stimulus positive regulation of T cell proliferation positive regulation of tyrosine phosphorylation of Stat1 protein positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity interleukin-27 receptor activity positive regulation of osteoblast differentiation positive regulation of anti-apoptosis leukemia inhibitory factor signaling pathway interleukin-27-mediated signaling pathway ciliary neurotrophic factor receptor complex ciliary neurotrophic factor-mediated signaling pathway	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
204122_at	0.495	5.647	2.333	3.378e-02	0.275	-3.822	TYROBP	TYRO protein tyrosine kinase binding protein	19	-41087142	NM_003332	7305	19q13.1	Hs.515369	39	receptor signaling protein activity protein binding integral to plasma membrane cellular defense response intracellular signaling cascade membrane	Natural killer cell mediated cytotoxicity
1564112_at	0.185	6.060	2.333	3.378e-02	0.275	-3.822	FAM71A	family with sequence similarity 71, member A	1	210864438	AK097437	149647	1q32.3	Hs.129293	4
211666_x_at	0.649	9.491	2.333	3.379e-02	0.275	-3.822	RPL3	ribosomal protein L3	22	-38038832	L22453	6122	22q13	Hs.119598	24	RNA binding structural constituent of ribosome protein binding intracellular nucleolus cytoplasm cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
1560201_at	0.214	2.807	2.333	3.379e-02	0.275	-3.822	ZNF713	zinc finger protein 713	7	55947824	AK097282	349075	7p11.2	Hs.660834	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
230774_at	-0.450	5.504	-2.333	3.380e-02	0.275	-3.822	PTGR2	prostaglandin reductase 2	14	73388286, 73388299, 73388373	BE465894	145482	14q24.3	Hs.632344	9	binding nucleus nucleolus cytoplasm zinc ion binding oxidoreductase activity 15-oxoprostaglandin 13-oxidase activity oxidation reduction
231895_at	-0.291	3.996	-2.332	3.381e-02	0.275	-3.823	SASS6	spindle assembly 6 homolog (C. elegans)	1	-100321689	AA501453	163786	1p21.2	Hs.591447	7	centrosome centrosome cell cycle centrosome duplication
217961_at	-0.342	7.709	-2.332	3.382e-02	0.275	-3.823	SLC25A38	solute carrier family 25, member 38	3	39399818	NM_017875	54977	3p22.1	Hs.369615	7	binding mitochondrion mitochondrial inner membrane heme biosynthetic process transport membrane integral to membrane erythrocyte differentiation
224177_s_at	-0.293	6.290	-2.332	3.384e-02	0.276	-3.823	CXorf26	chromosome X open reading frame 26	X	75309172	AF151079	51260	Xq13.3	Hs.370100	6	molecular_function cellular_component biological_process
222837_s_at	-0.658	4.893	-2.332	3.385e-02	0.276	-3.824	NARG1	NMDA receptor regulated 1	4	140442125	AF327722	80155	4q31.1	Hs.715706	17	angiogenesis protein binding nucleus transcription factor complex cytoplasm N-terminal protein amino acid acetylation multicellular organismal development N-acetyltransferase activity cell differentiation ribosome binding regulation of transcription positive regulation of transcription, DNA-dependent
207004_at	0.304	6.470	2.331	3.390e-02	0.276	-3.825	BCL2	B-cell CLL/lymphoma 2	18	-59136166, -58941558	NM_000657	596	18q21.3 18q21.33	Hs.150749	705	G1/S transition of mitotic cell cycle protein phosphatase type 2A complex cell morphogenesis response to acid ovarian follicle development ureteric bud development branching involved in ureteric bud morphogenesis behavioral fear response response to hypoxia B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development renal system process intracellular membrane fraction nucleus cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol calcineurin complex protein amino acid dephosphorylation melanin metabolic process oxygen and reactive oxygen species metabolic process regulation of nitrogen utilization anti-apoptosis humoral immune response response to oxidative stress actin filament organization female pregnancy cell aging response to nutrient transcription factor binding cell death positive regulation of cell proliferation male gonad development activation of pro-apoptotic gene products response to radiation response to heat response to external stimulus response to toxin post-embryonic development organ morphogenesis response to inorganic substance response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration membrane integral to membrane cell-cell adhesion transcription activator activity peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis hemopoiesis negative regulation of ossification negative regulation of cell growth negative regulation of cell migration response to caffeine hair follicle morphogenesis axon regeneration regulation of protein stability nuclear membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization negative regulation of myeloid cell apoptosis T cell differentiation in the thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine stimulus response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation response to drug response to hydrogen peroxide protein homodimerization activity T cell homeostasis positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment response to peptide hormone stimulus regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis ear development response to estrogen stimulus regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability protein heterodimerization activity focal adhesion formation positive regulation of pigmentation during development spleen development thymus development gut morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue response to glucocorticoid stimulus BH3 domain binding defense response to virus regulation of cell cycle response to protein stimulus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport apoptosis in response to endoplasmic reticulum stress	Apoptosis Focal adhesion Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Prostate cancer Small cell lung cancer
220816_at	0.243	5.461	2.331	3.393e-02	0.276	-3.826	LPAR3	lysophosphatidic acid receptor 3	1	-85051673	NM_012152	23566	1p22.3	Hs.674915	19	activation of MAPK activity lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger elevation of cytosolic calcium ion concentration synaptic transmission lipid binding bleb formation positive regulation of MAPKKK cascade	Neuroactive ligand-receptor interaction
220510_at	0.227	6.815	2.331	3.393e-02	0.276	-3.826	RHBG	Rh family, B glycoprotein (gene/pseudogene)	1	154605626	NM_020407	57127	1q21.3	Hs.131835	16	plasma membrane integral to plasma membrane transport ammonium transmembrane transporter activity spectrin-associated cytoskeleton basolateral plasma membrane basolateral plasma membrane ankyrin binding cytoplasmic vesicle anchored to plasma membrane ammonia transporter activity ammonia transporter activity transepithelial ammonium transport
226804_at	0.269	4.386	2.330	3.394e-02	0.276	-3.826	FAM20A	family with sequence similarity 20, member A	17	-64042852, -64042852	AI632223	54757	17q24.2	Hs.268874	5	extracellular region
214047_s_at	-0.348	7.459	-2.330	3.395e-02	0.276	-3.826	MBD4	methyl-CpG binding domain protein 4	3	-130632482	AI913365	8930	3q21-q22	Hs.35947	34	DNA binding satellite DNA binding endodeoxyribonuclease activity protein binding nucleus nucleolus base-excision repair response to DNA damage stimulus hydrolase activity depyrimidination	Base excision repair
226014_at	-0.321	4.683	-2.330	3.399e-02	0.276	-3.827	EIF3F	eukaryotic translation initiation factor 3, subunit F	11	7965442	BF115977	8665	11p15.4	Hs.516023	26	translation initiation factor activity translation initiation factor activity translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex translational initiation translational initiation
242429_at	0.305	3.550	2.330	3.399e-02	0.276	-3.827	ZNF567	zinc finger protein 567	19	41872141	BF435183	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
32209_at	-0.341	9.088	-2.329	3.402e-02	0.276	-3.828	FAM89B	family with sequence similarity 89, member B	11	65096395	AF052151	23625	11q23	Hs.25723	7
219594_at	-0.784	6.774	-2.329	3.402e-02	0.276	-3.828	NINJ2	ninjurin 2	12	-543722	NM_016533	4815	12p13	Hs.656450	5	protein binding integral to plasma membrane cell adhesion neuron adhesion nervous system development membrane tissue regeneration
211774_s_at	0.431	6.349	2.329	3.404e-02	0.277	-3.829	MMACHC	methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria	1	45738442	BC006122	25974	1p34.1	Hs.13024	11	cobalamin binding cobalt ion binding
202366_at	0.258	7.698	2.329	3.404e-02	0.277	-3.829	ACADS	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	12	119647953	NM_000017	35	12q22-qter	Hs.507076	24	acyl-CoA binding butyryl-CoA dehydrogenase activity mitochondrion mitochondrial matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation electron carrier activity response to starvation FAD binding response to glucocorticoid stimulus oxidation reduction	Fatty acid metabolism Valine, leucine and isoleucine degradation Butanoate metabolism Metabolic pathways
212115_at	0.183	6.959	2.329	3.406e-02	0.277	-3.829	HN1L	hematological and neurological expressed 1-like	16	1668278	AK023154	90861	16p13.3	Hs.513261	8	nucleus cytoplasm
221817_at	0.189	6.267	2.329	3.406e-02	0.277	-3.829	DOLPP1	dolichyl pyrophosphate phosphatase 1	9	130883203	AI684664	57171	9q34.1	Hs.21701	6	endoplasmic reticulum protein amino acid N-linked glycosylation membrane integral to membrane hydrolase activity integral to endoplasmic reticulum membrane dolichyldiphosphatase activity	N-Glycan biosynthesis Biosynthesis of terpenoids and steroids
226841_at	0.397	4.907	2.328	3.407e-02	0.277	-3.829	MPEG1	macrophage expressed 1	11	-58732558	BF590697	219972	11q12.1	Hs.718450	4	membrane integral to membrane
225341_at	0.307	6.223	2.328	3.408e-02	0.277	-3.830	MTERFD3	MTERF domain containing 3	12	-105895198	BF697312	80298	12q24.1	Hs.5009	6	mitochondrion transcription termination regulation of transcription
231251_at	0.278	3.737	2.328	3.409e-02	0.277	-3.830	WIPF2	WAS/WASL interacting protein family, member 2	17	35629099	AW295547	147179	17q21.1-q21.2	Hs.421622 Hs.705989	11	actin binding cytoplasm cytoskeleton
1556730_at	0.195	2.964	2.328	3.410e-02	0.277	-3.830	LOC652993	hypothetical LOC652993	12		AK074510	652993	12q21	Hs.585591	1
200793_s_at	0.289	10.081	2.328	3.410e-02	0.277	-3.830	ACO2	aconitase 2, mitochondrial	22	40195074	NM_001098	50	22q11.2-q13.31 22q13.2	Hs.643610 Hs.712617	26	aconitate hydratase activity aconitate hydratase activity iron ion binding nucleus mitochondrion mitochondrial matrix generation of precursor metabolites and energy tricarboxylic acid cycle citrate metabolic process metabolic process lyase activity metal ion binding 4 iron, 4 sulfur cluster binding	Citrate cycle (TCA cycle) Glyoxylate and dicarboxylate metabolism Reductive carboxylate cycle (CO2 fixation) Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
224929_at	0.186	5.418	2.328	3.411e-02	0.277	-3.831	TMEM173	transmembrane protein 173	5	-138835732	AA100891	340061	5q31.2	Hs.379754	8	mitochondrion mitochondrial outer membrane endoplasmic reticulum plasma membrane apoptosis integral to membrane innate immune response	RIG-I-like receptor signaling pathway
204640_s_at	-0.362	8.436	-2.328	3.413e-02	0.277	-3.831	SPOP	speckle-type POZ protein	17	-45031244	NM_003563	8405	17q21.33	Hs.463382 Hs.718421	27	protein binding nucleus mRNA processing modification-dependent protein catabolic process
231034_s_at	0.274	4.452	2.328	3.413e-02	0.277	-3.831	NHSL1	NHS-like 1	6	-138784873, -138784873	AI871589	57224	6q23.3	Hs.652741	3
212474_at	-0.338	5.909	-2.327	3.413e-02	0.277	-3.831	AVL9	AVL9 homolog (S. cerevisiase)	7	32501700	D87682	23080	7p14.3	Hs.128056	5	membrane integral to membrane
232702_at	-0.303	6.294	-2.327	3.414e-02	0.277	-3.831	RABGAP1L	RAB GTPase activating protein 1-like	1	172395256, 173111306	BG397461	9910	1q24	Hs.585378	9	GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity
232160_s_at	-0.295	6.866	-2.327	3.414e-02	0.277	-3.831	TNIP2	TNFAIP3 interacting protein 2	4	-2713184, -2713184	AL137262	79155	4p16.3	Hs.719161	20	protein binding cytoplasm I-kappaB kinase/NF-kappaB cascade
226544_x_at	-0.261	7.166	-2.327	3.415e-02	0.277	-3.831	MUTED	muted homolog (mouse)	6	-7959213	AV734582	63915	6p25.1-p24.3	Hs.719272	10	protein binding
230124_at	0.234	4.385	2.327	3.415e-02	0.277	-3.831	TMEM30B	transmembrane protein 30B	14	-60813841	BE218611	161291	14q23.1	Hs.146180	5	membrane integral to membrane
1557155_a_at	0.411	4.720	2.327	3.416e-02	0.277	-3.832	FLJ30375	hypothetical protein LOC440982	3		AI367357	440982	3q24	Hs.535724	1
201229_s_at	-0.432	7.929	-2.327	3.417e-02	0.277	-3.832	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	BC000422	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
224378_x_at	0.243	7.995	2.327	3.417e-02	0.277	-3.832	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	20	32598352, 32610179	AF276658	84557	20cen-q13	Hs.632273	29	autophagic vacuole formation protein binding cytoplasm autophagic vacuole cytosol microtubule autophagy phosphatidylethanolamine binding modification-dependent protein catabolic process organelle membrane cytoplasmic vesicle
235822_at	0.370	6.208	2.327	3.419e-02	0.277	-3.833	COQ9	coenzyme Q9 homolog (S. cerevisiae)	16	56038902	AW273049	57017	16q21	Hs.513632	7	mitochondrion ubiquinone biosynthetic process
1569973_at	-1.091	5.374	-2.326	3.420e-02	0.277	-3.833	SEPT13	septin 13	7	-45729914	BC015774	641977	7p12.3	Hs.520804	6	protein binding GTP binding cell cycle septin complex
227479_at	0.185	6.909	2.326	3.423e-02	0.277	-3.834	KIAA1244	KIAA1244	6	138524916	AV712413	57221	6q23.3	Hs.656215	5	ARF guanyl-nucleotide exchange factor activity intracellular membrane integral to membrane regulation of ARF protein signal transduction
215101_s_at	0.208	3.350	2.326	3.424e-02	0.277	-3.834	CXCL5	chemokine (C-X-C motif) ligand 5	4	-75080222	BG166705	6374	4q12-q13	Hs.89714	49	extracellular region extracellular space chemotaxis immune response signal transduction cell-cell signaling chemokine activity positive regulation of cell proliferation	Cytokine-cytokine receptor interaction Chemokine signaling pathway
218325_s_at	0.303	7.010	2.326	3.425e-02	0.277	-3.834	DIDO1	death inducer-obliterator 1	20	-61006799, -61006799, -60989013, -60979534	NM_022105	11083	20q13.33	Hs.517172	18	protein binding nucleus cytoplasm transcription apoptosis zinc ion binding metal ion binding
219118_at	0.310	4.193	2.326	3.426e-02	0.277	-3.834	FKBP11	FK506 binding protein 11, 19 kDa	12	-47603175, -47602009, -47602009	NM_016594	51303	12q13.12	Hs.655103	5	peptidyl-prolyl cis-trans isomerase activity protein folding membrane integral to membrane isomerase activity
227255_at	-0.490	6.289	-2.325	3.427e-02	0.277	-3.835	PDIK1L	PDLIM1 interacting kinase 1 like	1	26310242, 26310854	AI806633	149420	1p36.11	Hs.468801	6	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity
1554376_s_at	0.226	6.284	2.325	3.428e-02	0.277	-3.835	PTPLA	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A	10	-17671963	BC027709	9200	10p14-p13	Hs.114062	6	multicellular organismal development membrane integral to membrane
225090_at	-0.227	6.892	-2.325	3.428e-02	0.277	-3.835	SYVN1	synovial apoptosis inhibitor 1, synoviolin	11	-64651326	AA844682	84447	11q13	Hs.715498	30	in utero embryonic development protein binding nucleus nucleolus endoplasmic reticulum anti-apoptosis response to stress zinc ion binding membrane integral to membrane ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process ER-associated protein catabolic process metal ion binding	Ubiquitin mediated proteolysis
223305_at	0.209	5.925	2.325	3.428e-02	0.277	-3.835	TMEM216	transmembrane protein 216	11	60916440	AF151078	51259	11q13.1	Hs.26745	3	membrane integral to membrane
236746_at	0.254	4.424	2.325	3.429e-02	0.277	-3.835	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	18	31488530	AA513464	2589	18q12.1	Hs.514806	26	polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm	O-Glycan biosynthesis Metabolic pathways
203615_x_at	0.472	7.032	2.325	3.430e-02	0.277	-3.835	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	16	-28524418, -28524418, -28524416	NM_001055	6817	16p12.1	Hs.567342	134	aryl sulfotransferase activity cytoplasm catecholamine metabolic process lipid metabolic process steroid metabolic process amine metabolic process transferase activity	Sulfur metabolism
37201_at	-0.809	7.413	-2.325	3.432e-02	0.277	-3.836	ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	3	-52822045	D38535	3700	3p21-p14	Hs.709406	19	serine-type endopeptidase inhibitor activity extracellular region acute-phase response hyaluronan metabolic process
210956_at	0.213	4.022	2.324	3.435e-02	0.277	-3.837	PPYR1	pancreatic polypeptide receptor 1	10	46503539	U42387	5540	10q11.2	Hs.524719	14	peptide YY receptor activity pancreatic polypeptide receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway digestion feeding behavior blood circulation	Neuroactive ligand-receptor interaction
231973_s_at	-0.495	4.745	-2.324	3.436e-02	0.277	-3.837	ANAPC1	anaphase promoting complex subunit 1	2	-112243110	AK001223	64682	2q12.1	Hs.436527	26	nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle Ubiquitin mediated proteolysis
222381_at	0.208	5.057	2.324	3.438e-02	0.277	-3.837	PDCD6	programmed cell death 6	5	324735	AI907083	10016	5p15.33	Hs.50823	36	calcium ion binding nucleus endoplasmic reticulum apoptosis induction of apoptosis by extracellular signals membrane calcium-dependent protein binding response to calcium ion
243594_x_at	0.269	4.901	2.324	3.438e-02	0.277	-3.837	SPIRE2	spire homolog 2 (Drosophila)	16	88422407	AA553722	84501	16q24	Hs.461786	3	actin binding cytoplasm cytoskeleton transport zinc ion binding	Dorso-ventral axis formation
225927_at	0.261	6.647	2.324	3.439e-02	0.277	-3.838	MAP3K1	mitogen-activated protein kinase kinase kinase 1	5	56146656	AA541479	4214	5q11.2	Hs.653654	80	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding cellular_component cytosol protein amino acid phosphorylation transforming growth factor beta receptor signaling pathway I-kappaB kinase/NF-kappaB cascade activation of JUN kinase activity zinc ion binding JUN kinase kinase activity apoptotic mitochondrial changes transferase activity regulation of cell migration positive regulation of actin filament polymerization wound healing identical protein binding camera-type eye development	MAPK signaling pathway Ubiquitin mediated proteolysis RIG-I-like receptor signaling pathway Neurotrophin signaling pathway GnRH signaling pathway
226322_at	-0.395	8.258	-2.324	3.439e-02	0.277	-3.838	TMTC1	transmembrane and tetratricopeptide repeat containing 1	12	-29545023	BF109231	83857	12p11.22	Hs.401954	3	binding membrane integral to membrane
240479_at	0.284	5.098	2.324	3.439e-02	0.277	-3.838	HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	6	-114483442	AW449310	222537	6q21	Hs.645477	8	protein binding Golgi apparatus protein amino acid sulfation sulfotransferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane integral to membrane transferase activity regulation of virion penetration into host cell 3'-phosphoadenosine 5'-phosphosulfate binding negative regulation of coagulation	Heparan sulfate biosynthesis
204812_at	-0.294	6.054	-2.323	3.441e-02	0.278	-3.838	ZW10	ZW10, kinetochore associated, homolog (Drosophila)	11	-113109118	NM_004724	9183	11q23.2	Hs.503886	24	mitotic sister chromatid segregation condensed chromosome kinetochore spindle pole protein binding nucleus cytoplasm endoplasmic reticulum kinetochore microtubule protein complex assembly ER to Golgi vesicle-mediated transport cell cycle mitotic cell cycle checkpoint regulation of exit from mitosis meiosis protein transport membrane vesicle-mediated transport centromeric DNA binding cell division
205382_s_at	0.575	8.853	2.323	3.445e-02	0.278	-3.839	CFD	complement factor D (adipsin)	19	810664	NM_001928	1675	19p13.3	Hs.155597	17	serine-type endopeptidase activity extracellular region extracellular region extracellular space proteolysis complement activation, alternative pathway complement activation, alternative pathway peptidase activity platelet alpha granule lumen	Complement and coagulation cascades
231406_at	0.231	5.101	2.323	3.446e-02	0.278	-3.839	ORAI2	ORAI calcium release-activated calcium modulator 2	7	101861000	AW205664	80228	7q22.1	Hs.363308	12	membrane integral to membrane
226090_x_at	-0.317	5.883	-2.322	3.447e-02	0.278	-3.840	RABL3	RAB, member of RAS oncogene family-like 3	3	-121888217	AK025772	285282	3q13.33	Hs.444360	1	nucleotide binding GTP binding intracellular small GTPase mediated signal transduction
217938_s_at	-0.292	9.082	-2.322	3.451e-02	0.278	-3.841	KCMF1	potassium channel modulatory factor 1	2	85051741	NM_020122	56888	2p11.2	Hs.654968	7	intracellular zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding
222455_s_at	0.389	4.858	2.322	3.452e-02	0.278	-3.841	PARVA	parvin, alpha	11	12355721	AF237771	55742	11p15.3	Hs.607144	17	actin binding protein binding nucleus cytoplasm cytoskeleton plasma membrane focal adhesion cell adhesion lamellipodium cell junction	Focal adhesion
212645_x_at	0.249	7.898	2.321	3.454e-02	0.278	-3.842	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	2	27966985, 27967060	AL566299	9577	2p23.2	Hs.258314	20	nuclear ubiquitin ligase complex peroxisome targeting sequence binding tumor necrosis factor receptor binding protein binding nucleus cytoplasm double-strand break repair apoptosis response to DNA damage stimulus signal transduction response to ionizing radiation chromatin modification G2/M transition DNA damage checkpoint polyubiquitin binding positive regulation of DNA repair positive regulation of anti-apoptosis BRCA1-A complex BRISC complex
206768_at	-0.515	11.342	-2.321	3.454e-02	0.278	-3.842	RPL3L	ribosomal protein L3-like	16	-1934580	NM_005061	6123	16p13.3	Hs.657266	7	RNA binding structural constituent of ribosome intracellular cytosol ribosome translational elongation	Ribosome
217624_at	-0.275	3.385	-2.321	3.455e-02	0.278	-3.842	PDAP1	PDGFA associated protein 1	7	-98830524	AA464753	11333	7q22.1	Hs.632296	8	signal transduction cell proliferation
220777_at	-0.415	5.829	-2.321	3.456e-02	0.278	-3.842	KIF13A	kinesin family member 13A	6	-17871902, -17868563	NM_022113	63971	6p23	Hs.189915	14	nucleotide binding microtubule motor activity protein binding ATP binding microtubule microtubule-based movement protein transport
217848_s_at	0.293	10.520	2.321	3.456e-02	0.278	-3.842	PPA1	pyrophosphatase (inorganic) 1	10	-71632591	NM_021129	5464	10q11.1-q24	Hs.437403	19	magnesium ion binding inorganic diphosphatase activity cytoplasm cytosol phosphate metabolic process hydrolase activity	Oxidative phosphorylation
207983_s_at	-0.363	6.437	-2.321	3.460e-02	0.278	-3.843	STAG2	stromal antigen 2	X	122922155, 122923236	NM_006603	10735	Xq25	Hs.496710 Hs.624663	18	chromatin protein binding nucleus cytoskeleton cell cycle chromosome segregation mitosis meiosis biological_process cell division	Cell cycle
240528_s_at	-0.329	4.522	-2.321	3.460e-02	0.278	-3.843	EXOC4	exocyst complex component 4	7	132588362, 132588362	AI964022	60412	7q31	Hs.321273	30	exocyst cytoplasm vesicle docking during exocytosis protein transport protein N-terminus binding	Tight junction
226387_at	-0.341	5.581	-2.320	3.463e-02	0.278	-3.844	RSBN1L	round spermatid basic protein 1-like	7	77163678	AI439157	222194	7q11.23	Hs.592289 Hs.72451	4	nucleus
227942_s_at	-0.338	7.313	-2.320	3.464e-02	0.278	-3.844	CRIPT	cysteine-rich PDZ-binding protein	2	46697828	BF591360	9419	2p21	Hs.133998	11	cytoplasm cell junction cell projection dendritic spine synapse
217894_at	-0.472	5.910	-2.320	3.466e-02	0.278	-3.845	KCTD3	potassium channel tetramerisation domain containing 3	1	213807357	NM_016121	51133	1q41	Hs.335139	6	voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane
203845_at	-0.445	8.394	-2.320	3.466e-02	0.278	-3.845	KAT2B	K(lysine) acetyltransferase 2B	3	20056527	AV727449	8850	3p24	Hs.533055	163	PCAF complex transcription coactivator activity histone acetyltransferase activity nucleus nucleoplasm chromatin remodeling regulation of transcription, DNA-dependent cell cycle cell cycle arrest N-acetyltransferase activity metabolic process negative regulation of cell proliferation histone acetylation chromatin remodeling complex transferase activity N-terminal peptidyl-lysine acetylation histone deacetylase binding interspecies interaction between organisms	Notch signaling pathway
226219_at	0.277	3.556	2.320	3.467e-02	0.278	-3.845	ARHGAP30	Rho GTPase activating protein 30	1	-159283355	AW575123	257106	1q23.3	Hs.389374	4	GTPase activator activity intracellular signal transduction
214875_x_at	0.184	6.580	2.319	3.469e-02	0.278	-3.845	APLP2	amyloid beta (A4) precursor-like protein 2	11	129444925	AW001847	334	11q23-q25 11q24	Hs.709184	43	DNA binding serine-type endopeptidase inhibitor activity nucleus plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane peptidase inhibitor activity identical protein binding
218182_s_at	-0.231	4.107	-2.319	3.469e-02	0.278	-3.845	CLDN1	claudin 1	3	-191506186	NM_021101	9076	3q28-q29	Hs.439060	63	structural molecule activity plasma membrane integral to plasma membrane tight junction cell adhesion calcium-independent cell-cell adhesion cell junction identical protein binding interspecies interaction between organisms	Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration Pathogenic Escherichia coli infection - EHEC
1558689_a_at	0.171	3.184	2.319	3.469e-02	0.278	-3.845	LOC441461	hypothetical LOC441461	9		BG701300	441461	9q31.1	Hs.163155	1
200058_s_at	-0.275	8.360	-2.319	3.469e-02	0.278	-3.845	SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	2	-96303800	BC001417	23020	2q11.2	Hs.246112	25	nucleotide binding cis assembly of pre-catalytic spliceosome nuclear mRNA splicing, via spliceosome nucleic acid binding helicase activity protein binding ATP binding nucleus spliceosomal complex U5 snRNP ATP-dependent helicase activity RNA splicing hydrolase activity
1556630_at	-0.301	3.836	-2.319	3.471e-02	0.278	-3.846	CASC2	cancer susceptibility candidate 2	10	119796321, 119796321	AJ344228	255082	10q26.11	Hs.89387	3
241700_at	-0.380	4.856	-2.319	3.471e-02	0.278	-3.846	ZFHX4	zinc finger homeobox 4	8	77756069	AW963185	79776	8q21.11	Hs.458973	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
1557347_at	0.158	5.498	2.319	3.473e-02	0.279	-3.846	MCPH1	microcephalin 1	8	6251528	N21605	79648	8p23.1	Hs.709634	32	intracellular centrosome
201209_at	0.275	6.495	2.319	3.473e-02	0.279	-3.846	HDAC1	histone deacetylase 1	1	32530294	NM_004964	3065	1p34	Hs.88556	295	transcription factor activity histone deacetylase activity nucleus cytoplasm chromatin remodeling anti-apoptosis transcription factor binding transcription factor binding positive regulation of cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of receptor biosynthetic process transcription activator activity histone deacetylation Sin3 complex NuRD complex hydrolase activity enzyme binding identical protein binding interspecies interaction between organisms regulation of transcription	Cell cycle Notch signaling pathway Huntington's disease Pathways in cancer Chronic myeloid leukemia
238494_at	-0.476	6.661	-2.318	3.475e-02	0.279	-3.847	TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	2	238893923	AI623155	26146	2q37.3	Hs.631898	5	cytoplasm cytoskeleton
225445_at	-0.276	7.067	-2.318	3.475e-02	0.279	-3.847	UBN2	ubinuclein 2	7	138566770	AI332346	254048	7q34	Hs.153458 Hs.511486 Hs.624688	4
210514_x_at	0.240	7.822	2.318	3.478e-02	0.279	-3.848	HLA-G	major histocompatibility complex, class I, G	6	29902734, 1247153, 1049287	AF226990	3135	6p21.3	Hs.512152	316	antigen processing and presentation of peptide antigen via MHC class I immune response cellular defense response membrane integral to membrane antigen processing and presentation MHC class I receptor activity MHC class I protein complex	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
223510_at	0.251	4.355	2.318	3.479e-02	0.279	-3.848	NRP2	neuropilin 2	2	206255468, 206255468, 206255468	AF280545	8828	2q33.3	Hs.471200	44	receptor activity vascular endothelial growth factor receptor activity membrane fraction plasma membrane cell adhesion multicellular organismal development nervous system development axon guidance integral to membrane cell differentiation
212848_s_at	-0.499	10.238	-2.318	3.479e-02	0.279	-3.848	C9orf3	chromosome 9 open reading frame 3	9	96528814	BG036668	84909	9q22.32	Hs.434253	5	aminopeptidase activity binding cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding leukotriene biosynthetic process metal ion binding
208335_s_at	0.423	5.922	2.318	3.480e-02	0.279	-3.848	DARC	Duffy blood group, chemokine receptor	1	157441133, 157441824	NM_002036	2532	1q21-q22	Hs.153381	65	G-protein coupled receptor activity chemokine receptor activity plasma membrane defense response signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
236874_at	0.236	5.570	2.317	3.481e-02	0.279	-3.849	LOC100128071	similar to hCG41624	1		AI634963	100128071	1p35.1	Hs.660539	1
212511_at	-0.336	6.778	-2.317	3.482e-02	0.279	-3.849	PICALM	phosphatidylinositol binding clathrin assembly protein	11	-85346132	AI766247	8301	11q14	Hs.163893	22	phospholipid binding phosphatidylinositol binding Golgi apparatus coated pit protein complex assembly receptor-mediated endocytosis membrane clathrin coat clathrin-coated vesicle clathrin binding cytoplasmic vesicle clathrin coat assembly
243386_at	-0.283	7.551	-2.317	3.483e-02	0.279	-3.849	CASZ1	castor zinc finger 1	1	-10629856, -10619252	AI085338	54897	1p36.22	Hs.439894	10	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
208054_at	-0.172	2.643	-2.317	3.484e-02	0.279	-3.849	HERC4	hect domain and RLD 4	10	-69351661	NM_015601	26091	10q21.3	Hs.51891	7	intracellular cytoplasm cytosol protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
201698_s_at	0.149	7.575	2.317	3.484e-02	0.279	-3.849	SFRS9	splicing factor, arginine/serine-rich 9	12	-119383853	NM_003769	8683	12q24.31	Hs.706889	26	nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding nucleus mRNA splice site selection RNA splicing
224701_at	0.290	6.065	2.317	3.486e-02	0.279	-3.850	PARP14	poly (ADP-ribose) polymerase family, member 14	3	123882361	AA056548	54625	3q21.1	Hs.518203	9	NAD+ ADP-ribosyltransferase activity protein binding nucleus cytoplasm plasma membrane transferase activity, transferring glycosyl groups regulation of transcription
237981_at	-0.593	9.606	-2.317	3.486e-02	0.279	-3.850	CMYA5	cardiomyopathy associated 5	5	79021414	AA195941	202333	5q14.1	Hs.482625	7	cytoplasm identical protein binding perinuclear region of cytoplasm
223029_s_at	0.157	6.342	2.316	3.487e-02	0.279	-3.850	TRAF7	TNF receptor-associated factor 7	16	2145799	AI806564	84231	16p13.3	Hs.643537 Hs.713632	6	ubiquitin ligase complex activation of MAPKKK activity ubiquitin-protein ligase activity GTP binding zinc ion binding protein ubiquitination ligase activity regulation of exocytosis modification-dependent protein catabolic process intrinsic to plasma membrane cytoplasmic vesicle exocrine system development identical protein binding regulation of apoptosis positive regulation of MAPKKK cascade regulation of transcription metal ion binding
209068_at	-0.439	7.173	-2.316	3.487e-02	0.279	-3.850	HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	4	-83563370	D89678	9987	4q13-q21	Hs.527105	14	nucleotide binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding protein binding nucleus cytoplasm RNA processing poly(A) RNA binding heterogeneous nuclear ribonucleoprotein complex regulation of transcription
204171_at	-0.267	5.842	-2.316	3.488e-02	0.279	-3.850	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17	55325224	NM_003161	6198	17q23.1	Hs.463642	123	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation signal transduction transferase activity synaptosome cell junction synapse	ErbB signaling pathway mTOR signaling pathway TGF-beta signaling pathway Fc gamma R-mediated phagocytosis Insulin signaling pathway Acute myeloid leukemia
228227_at	0.215	4.421	2.316	3.491e-02	0.279	-3.851	ITGB1BP1	integrin beta 1 binding protein 1	2	-9463265	BF435077	9270	2p25.2	Hs.467662	22	ruffle protein binding cytoplasm cytosol cell-matrix adhesion protein kinase cascade membrane cell migration lamellipodium
201892_s_at	-0.329	9.409	-2.316	3.491e-02	0.279	-3.851	IMPDH2	IMP (inosine monophosphate) dehydrogenase 2	3	-49036765	NM_000884	3615	3p21.2	Hs.654400	31	IMP dehydrogenase activity IMP dehydrogenase activity protein binding cytosol purine nucleotide biosynthetic process GMP biosynthetic process oxidoreductase activity potassium ion binding lymphocyte proliferation metal ion binding oxidation reduction	Purine metabolism Drug metabolism - other enzymes Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
1553634_a_at	0.227	4.011	2.316	3.491e-02	0.279	-3.851	FLJ40852	hypothetical LOC285962	7	-141050606	NM_173677	285962	7q34	Hs.17589	2
210162_s_at	-0.428	6.271	-2.316	3.493e-02	0.279	-3.851	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	18	75256759, 75256759, 75261313	U08015	4772	18q23	Hs.534074 Hs.701518	83	transcription factor activity FK506 binding nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter intracellular signaling cascade transcription activator activity	Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway
225246_at	-0.254	4.306	-2.316	3.493e-02	0.279	-3.852	STIM2	stromal interaction molecule 2	4	26471461	T97323	57620	4p15.2	Hs.135763	15	calcium channel regulator activity calcium ion binding protein binding endoplasmic reticulum plasma membrane ion transport cellular calcium ion homeostasis integral to membrane negative regulation of calcium ion transport via store-operated calcium channel activity activation of store-operated calcium channel activity activation of store-operated calcium channel activity positive regulation of calcium ion transport positive regulation of calcium ion transport
200762_at	0.337	8.276	2.315	3.495e-02	0.279	-3.852	DPYSL2	dihydropyrimidinase-like 2	8	26491337	NM_001386	1808	8p22-p21	Hs.173381	40	dihydropyrimidinase activity protein binding cytoplasm mitochondrion cytoskeleton nucleobase, nucleoside, nucleotide and nucleic acid metabolic process signal transduction multicellular organismal development nervous system development hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cell differentiation axon dendrite cell soma	Axon guidance
238792_at	0.262	5.515	2.315	3.495e-02	0.279	-3.852	PCNX	pecanex homolog (Drosophila)	14	70443874	BF209668	22990	14q24.2	Hs.446559	10	membrane integral to membrane
221475_s_at	0.238	11.407	2.315	3.496e-02	0.279	-3.852	RPL15	ribosomal protein L15	3	23933642	NM_002948	6138	3p24.2	Hs.381219 Hs.695621	14	RNA binding structural constituent of ribosome intracellular cytosol ribosome translational elongation	Ribosome
202795_x_at	0.205	6.784	2.315	3.496e-02	0.279	-3.852	TRIOBP	TRIO and F-actin binding protein	22	36422940, 36472186, 36472186	NM_007032	11078	22q13.1	Hs.533030	20	actin binding protein binding nucleus cytoplasm actin cytoskeleton GTP-Rho binding actin modification myosin II binding barbed-end actin filament capping
225866_at	-0.275	8.184	-2.315	3.498e-02	0.279	-3.853	BXDC1	brix domain containing 1	6	111409983	AA976536	84154	6q21	Hs.372265	8	protein binding nucleus nucleolus
242639_at	-0.494	3.568	-2.315	3.498e-02	0.279	-3.853	NARG2	NMDA receptor regulated 2	15	-58499099	AW340004	79664	15q22.2	Hs.200943	6	nucleus
228535_at	-0.347	7.018	-2.315	3.499e-02	0.279	-3.853	RAD1	RAD1 homolog (S. pombe)	5	-34941124, -34941122	AI796010	5810	5p13.2	Hs.38114	44	cell cycle checkpoint DNA damage checkpoint damaged DNA binding protein binding nucleus DNA replication DNA repair response to DNA damage stimulus meiotic prophase I 3'-5' exonuclease activity 3'-5' exonuclease activity exodeoxyribonuclease III activity hydrolase activity
40446_at	-0.179	8.792	-2.315	3.500e-02	0.279	-3.853	PHF1	PHD finger protein 1	6	33486750	AL021366	5252	6p21.3	Hs.166204	15	nucleic acid binding transcription factor activity protein binding nucleus zinc ion binding chromatin modification regulation of transcription metal ion binding
1562581_at	0.252	4.926	2.315	3.500e-02	0.279	-3.853	LOC254028	hypothetical LOC254028	14		AK093210	254028	14q11.2	Hs.652569	2
227612_at	0.198	3.583	2.314	3.501e-02	0.279	-3.854	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	19	-11423142	R20763	1995	19p13.2	Hs.1701	8	nucleotide binding RNA binding multicellular organismal development nervous system development cell differentiation
207843_x_at	0.246	7.507	2.314	3.504e-02	0.279	-3.854	CYB5A	cytochrome b5 type A (microsomal)	18	-70071506	NM_001914	1528	18q23	Hs.465413	38	aldo-keto reductase activity cytochrome-c oxidase activity cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum microsome transport membrane integral to membrane heme binding electron transport chain metal ion binding
221049_s_at	0.175	6.959	2.314	3.507e-02	0.280	-3.855	POLL	polymerase (DNA directed), lambda	10	-103328628	NM_013274	27343	10q23	Hs.523230	47	DNA binding DNA-directed DNA polymerase activity intracellular nucleus DNA replication nucleotide-excision repair response to DNA damage stimulus somatic hypermutation of immunoglobulin genes transferase activity nucleotidyltransferase activity lyase activity manganese ion binding metal ion binding	Base excision repair Non-homologous end-joining
1566472_s_at	0.465	4.355	2.313	3.512e-02	0.280	-3.856	RETSAT	retinol saturase (all-trans-retinol 13,14-reductase)	2	-85422589	AK098125	54884	2p11.2	Hs.440401	11	nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane electron carrier activity membrane oxidoreductase activity retinol metabolic process all-trans-retinol 13,14-reductase activity oxidation reduction	Retinol metabolism
209939_x_at	0.465	8.223	2.313	3.514e-02	0.280	-3.857	CFLAR	CASP8 and FADD-like apoptosis regulator	2	201689060, 201689134, 201691631	AF005775	8837	2q33-q34	Hs.390736	163	cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms	Apoptosis
239837_at	0.267	4.945	2.312	3.515e-02	0.280	-3.857	ADAM11	ADAM metallopeptidase domain 11	17	40192093	T15748	4185	17q21.3	Hs.6088	11	metalloendopeptidase activity integrin binding plasma membrane proteolysis integrin-mediated signaling pathway zinc ion binding integral to membrane
218115_at	0.229	5.553	2.312	3.516e-02	0.280	-3.857	ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	19	-14091320	NM_018154	55723	19p13.12	Hs.26516	15	chromatin nucleus chromatin assembly or disassembly nucleosome assembly multicellular organismal development spermatogenesis chromatin modification cell differentiation histone binding regulation of transcription
1554514_at	-0.243	3.375	-2.312	3.518e-02	0.280	-3.858	ACSM5	acyl-CoA synthetase medium-chain family member 5	16	20328356	BC013753	54988	16p12.3	Hs.659606	3	nucleotide binding magnesium ion binding ATP binding GTP binding mitochondrion mitochondrial matrix lipid metabolic process fatty acid metabolic process metabolic process ligase activity butyrate-CoA ligase activity	Butanoate metabolism Metabolic pathways
225105_at	1.571	8.723	2.312	3.519e-02	0.280	-3.858	C12orf75	chromosome 12 open reading frame 75	12	104248543	BF969397	387882	12q23.3	Hs.368938	3
222708_s_at	-0.292	6.542	-2.312	3.519e-02	0.280	-3.858	STX17	syntaxin 17	9	101708735	AW014619	55014	9q31.1	Hs.709465	7	SNAP receptor activity nucleolus endoplasmic reticulum intracellular protein transport membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
212469_at	-0.227	7.255	-2.312	3.519e-02	0.280	-3.858	NIPBL	Nipped-B homolog (Drosophila)	5	36912617	AB019494	25836	5p13.2	Hs.481927	22	protein binding nucleus cell cycle cohesin loading complex maintenance of mitotic sister chromatid cohesion
200001_at	0.334	9.764	2.312	3.519e-02	0.280	-3.858	CAPNS1	calpain, small subunit 1	19	41322757	NM_001749	826	19q13.12	Hs.515371	29	calcium-dependent cysteine-type endopeptidase activity calcium ion binding protein binding nucleus cytoplasm plasma membrane positive regulation of cell proliferation
214797_s_at	0.362	6.045	2.311	3.521e-02	0.280	-3.859	PCTK3	PCTAIRE protein kinase 3	1	203740349	BC000281	5129	1q31-q32	Hs.445402	13	nucleotide binding cyclin-dependent protein kinase activity signal transducer activity protein binding ATP binding cellular_component protein amino acid phosphorylation signal transduction transferase activity
1554233_at	0.486	4.876	2.311	3.522e-02	0.280	-3.859	C1QTNF9	C1q and tumor necrosis factor related protein 9	13	23781715	BC040438	338872	13q12.12	Hs.362854	3	extracellular region
208881_x_at	-0.417	9.629	-2.311	3.524e-02	0.280	-3.859	IDI1	isopentenyl-diphosphate delta isomerase 1	10	-1075963	BC005247	3422	10p15.3	Hs.283652 Hs.719114	11	magnesium ion binding isopentenyl-diphosphate delta-isomerase activity peroxisome cytosol cholesterol biosynthetic process isoprenoid biosynthetic process carotenoid biosynthetic process hydrolase activity isomerase activity	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
236951_at	0.167	5.211	2.311	3.526e-02	0.280	-3.860	NSFL1C	NSFL1 (p97) cofactor (p47)	20	-1370810	BE550891	55968	20p13	Hs.12865	20	protein binding nucleus Golgi apparatus Golgi stack lipid binding
211615_s_at	0.204	9.279	2.311	3.526e-02	0.280	-3.860	LRPPRC	leucine-rich PPR-motif containing	2	-43966866	M92439	10128	2p21	Hs.368084	15	condensed nuclear chromosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus nuclear inner membrane nuclear outer membrane nucleoplasm cytoplasm mitochondrion cytoskeleton transport microtubule binding membrane mitochondrial nucleoid regulation of transcription mitochondrion transport along microtubule perinuclear region of cytoplasm beta-tubulin binding actin filament binding mRNA transport
230080_at	0.228	5.086	2.311	3.527e-02	0.280	-3.860	LOC285943	hypothetical protein LOC285943	7		T89711	285943	7p15.2	Hs.714774	1
1552853_at	0.278	3.869	2.311	3.527e-02	0.280	-3.860	VWA5B1	von Willebrand factor A domain containing 5B1	1	20489998	NM_144623	127731	1p36.12	Hs.205178	3	extracellular region
229419_at	-0.462	8.017	-2.311	3.527e-02	0.280	-3.860	FBXW7	F-box and WD repeat domain containing 7	4	-153461859, -153461859, -153461859	BF222826	55294	4q31.3	Hs.679796	71	protein binding nucleus protein ubiquitination modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
239813_at	0.234	3.663	2.311	3.528e-02	0.280	-3.860	IQCH	IQ motif containing H	15	65334241, 65334247	AA789195	64799	15q23	Hs.657894	5
240422_at	-0.223	2.610	-2.310	3.529e-02	0.280	-3.861	FMO5	flavin containing monooxygenase 5	1	-145124461, -145122508	AI935710	2330	1q21.1	Hs.642706 Hs.719397	18	monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome biological_process membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction	Drug metabolism - cytochrome P450
35974_at	0.246	4.400	2.310	3.530e-02	0.280	-3.861	LRMP	lymphoid-restricted membrane protein	12	25096507	U10485	4033	12p12.1	Hs.124922	9	cytoplasm endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane vesicle targeting vesicle fusion membrane
215946_x_at	0.276	5.094	2.310	3.530e-02	0.280	-3.861	IGLL3	immunoglobulin lambda-like polypeptide 3	22	24043887	AL022324	91353	22q11.2 22q11.23	Hs.567636	3
217437_s_at	0.233	6.316	2.310	3.530e-02	0.280	-3.861	TACC1	transforming, acidic coiled-coil containing protein 1	8	38704860, 38763878	AB029026	6867	8p11.22	Hs.279245	22	protein binding nucleus cytoplasm cell cycle cell division
219142_at	0.248	4.413	2.310	3.532e-02	0.280	-3.861	RASL11B	RAS-like, family 11, member B	4	53423251	NM_023940	65997	4q12	Hs.8035	5
1555548_at	0.232	4.621	2.310	3.535e-02	0.281	-3.862	NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	2	-240548828	AF453834	4705	2q37.3	Hs.277677	11	ATP binding mitochondrion mitochondrial respiratory chain complex I mitochondrial matrix mitochondrial electron transport, NADH to ubiquinone nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transport NADH dehydrogenase (ubiquinone) activity phosphotransferase activity, alcohol group as acceptor electron transport chain respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
214731_at	0.222	5.140	2.309	3.536e-02	0.281	-3.862	CTTNBP2NL	CTTNBP2 N-terminal like	1	112740322	AB037854	55917	1p13.2	Hs.485899	15	actin cytoskeleton
208338_at	0.231	4.060	2.309	3.538e-02	0.281	-3.863	P2RX3	purinergic receptor P2X, ligand-gated ion channel, 3	11	56862524	NM_002559	5024	11q12	Hs.146738	15	purinergic nucleotide receptor activity response to hypoxia receptor activity ATP-gated cation channel activity ion channel activity ATP binding integral to plasma membrane cation transport signal transduction neuromuscular synaptic transmission response to heat response to cold response to carbohydrate stimulus positive regulation of calcium ion transport into cytosol urinary bladder smooth muscle contraction membrane axon peristalsis response to ATP protein homodimerization activity intracellular part protein heterodimerization activity regulation of synaptic plasticity behavioral response to pain positive regulation of calcium-mediated signaling response to stimulus sensory perception of taste	Calcium signaling pathway Neuroactive ligand-receptor interaction
238432_at	0.373	5.421	2.309	3.539e-02	0.281	-3.863	FLJ35776	hypothetical LOC649446	18	3584111	AI275162	649446	18p11.31	Hs.19872	2
213025_at	-0.372	6.787	-2.309	3.540e-02	0.281	-3.863	THUMPD1	THUMP domain containing 1	16	-20652489	AL134904	55623	16p12.3	Hs.460232	5
227790_at	-0.590	4.820	-2.309	3.541e-02	0.281	-3.863	UBE2CBP	ubiquitin-conjugating enzyme E2C binding protein	6	-83658905	AV692609	90025	6q14.1	Hs.148609	2	cytoplasm ligase activity modification-dependent protein catabolic process
218118_s_at	0.286	8.965	2.309	3.541e-02	0.281	-3.864	TIMM23	translocase of inner mitochondrial membrane 23 homolog (yeast)	10	-51262093	NM_006327	10431	10q11.21-q11.23	Hs.499594 Hs.524308 Hs.536158 Hs.661964	9	protein binding mitochondrion mitochondrial inner membrane presequence translocase complex mitochondrial intermembrane space protein targeting to mitochondrion protein transporter activity P-P-bond-hydrolysis-driven protein transmembrane transporter activity membrane integral to membrane intracellular protein transmembrane transport
229696_at	-0.246	6.154	-2.309	3.541e-02	0.281	-3.864	FECH	ferrochelatase (protoporphyria)	18	-53363070	AI807483	2235	18q21.3	Hs.365365	61	ferrochelatase activity ferrochelatase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix generation of precursor metabolites and energy heme biosynthetic process ferrous iron binding response to light stimulus detection of UV membrane protoporphyrinogen IX metabolic process metal ion binding 2 iron, 2 sulfur cluster binding	Porphyrin and chlorophyll metabolism Metabolic pathways
209341_s_at	-0.620	7.254	-2.309	3.541e-02	0.281	-3.864	IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	8	42247985	AU153366	3551	8p11.2	Hs.597664	172	nucleotide binding B cell homeostasis ATP binding cytoplasm cytosol protein amino acid phosphorylation IkappaB kinase activity transcription activator activity transferase activity identical protein binding positive regulation of NF-kappaB transcription factor activity	MAPK signaling pathway Chemokine signaling pathway Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Pancreatic cancer Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer
211913_s_at	0.196	3.095	2.309	3.541e-02	0.281	-3.864	MERTK	c-mer proto-oncogene tyrosine kinase	2	112372661	L08961	10461	2q14.1	Hs.306178	32	nucleotide binding photoreceptor outer segment transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding soluble fraction integral to plasma membrane protein amino acid phosphorylation phagocytosis cell surface receptor linked signal transduction cell-cell signaling visual perception membrane transferase activity response to stimulus
223068_at	0.258	5.909	2.308	3.542e-02	0.281	-3.864	EML4	echinoderm microtubule associated protein like 4	2	42249993	AV707345	27436	2p22-p21	Hs.593614	22	molecular_function protein binding cytoplasm microtubule microtubule-based process mitosis
1566888_at	0.197	2.533	2.308	3.543e-02	0.281	-3.864	THADA	thyroid adenoma associated	2	-43311478, -43311478	BC037847	63892	2p21	Hs.369592	17	binding
213130_at	0.185	5.301	2.308	3.544e-02	0.281	-3.864	ZNF473	zinc finger protein 473	19	55221023	AB032967	25888	19q13.33	Hs.440553	8	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1557059_at	-0.185	4.881	-2.308	3.544e-02	0.281	-3.864	LOC254128	hypothetical protein LOC254128	2		AK098264	254128	2q14.2	Hs.712685	1
1569433_at	-0.173	1.937	-2.308	3.544e-02	0.281	-3.864	SAMD5	sterile alpha motif domain containing 5	6	147871755	BC020896	389432	6q24.3	Hs.567973	1
201414_s_at	-0.244	7.696	-2.308	3.545e-02	0.281	-3.865	NAP1L4	nucleosome assembly protein 1-like 4	11	-2922235	NM_005969	4676	11p15.5	Hs.501684 Hs.695395	12	nucleus chromatin assembly complex cytoplasm nucleosome assembly unfolded protein binding
206705_at	0.217	4.986	2.308	3.547e-02	0.281	-3.865	TULP1	tubby like protein 1	6	-35573628	NM_003322	7287	6p21.3	Hs.485208	20	protein binding visual perception response to stimulus
222689_at	0.422	3.515	2.308	3.547e-02	0.281	-3.865	ACER3	alkaline ceramidase 3	11	76249564	N51263	55331	11q13.5	Hs.23862	5	Golgi membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus ceramide metabolic process membrane integral to membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	Sphingolipid metabolism
212425_at	-0.392	6.087	-2.307	3.551e-02	0.281	-3.866	SCAMP1	secretory carrier membrane protein 1	5	77692094	AL049223	9522	5q13.3-q14.1	Hs.482587	22	protein binding endosome Golgi apparatus trans-Golgi network post-Golgi vesicle-mediated transport protein transport membrane integral to membrane recycling endosome membrane
204440_at	0.240	5.614	2.307	3.551e-02	0.281	-3.866	CD83	CD83 molecule	6	14225843	NM_004233	9308	6p23	Hs.595133	44	plasma membrane integral to plasma membrane defense response humoral immune response signal transduction external side of plasma membrane response to organic cyclic substance negative regulation of interleukin-4 production positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of CD4-positive, alpha beta T cell differentiation
230155_x_at	0.306	5.392	2.307	3.551e-02	0.281	-3.866	MSL1	male-specific lethal 1 homolog (Drosophila)	17	35532315	AI800794	339287	17q21.1	Hs.532786	5	nucleus chromatin modification
213900_at	-0.400	8.078	-2.307	3.552e-02	0.281	-3.866	FAM189A2	family with sequence similarity 189, member A2	9	71129307, 71134060	AA524029	9413	9q13-q21	Hs.118003	6	molecular_function cellular_component biological_process membrane integral to membrane
241670_x_at	0.289	5.155	2.307	3.553e-02	0.281	-3.867	LOC729177	hypothetical LOC729177	6		N22836	729177	6p22.3	Hs.712707	2
203897_at	0.192	8.890	2.307	3.553e-02	0.281	-3.867	LYRM1	LYR motif containing 1	16	20819057, 20819575	BE963444	57149	16p11.2	Hs.185489	6	nucleus
203515_s_at	0.227	7.363	2.307	3.554e-02	0.281	-3.867	PMVK	phosphomevalonate kinase	1	-153163831	NM_006556	10654	1q22	Hs.30954	12	nucleotide binding phosphomevalonate kinase activity protein binding ATP binding cytoplasm peroxisome protein amino acid phosphorylation cholesterol biosynthetic process transferase activity	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
238058_at	-0.370	9.301	-2.307	3.555e-02	0.281	-3.867	LOC150381	hypothetical LOC150381	22	44828389	AA603041	150381	22q13.31	Hs.659113	1
1553976_a_at	0.348	6.250	2.307	3.555e-02	0.281	-3.867	RP11-529I10.4	deleted in a mouse model of primary ciliary dyskinesia	10	103338078	BC031695	25911	10q24.32	Hs.658128	4	protein binding
219076_s_at	0.305	7.807	2.307	3.555e-02	0.281	-3.867	PXMP2	peroxisomal membrane protein 2, 22kDa	12	131774264	NM_018663	5827	12q24.33	Hs.430299	5	protein binding peroxisome membrane integral to membrane
202994_s_at	0.607	6.443	2.307	3.555e-02	0.281	-3.867	FBLN1	fibulin 1	22	44277382, 44277382, 44277382, 44277382	Z95331	2192	22q13.31	Hs.24601 Hs.593123	55	extracellular matrix structural constituent calcium ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space soluble fraction interspecies interaction between organisms
1558136_s_at	-0.273	7.191	-2.306	3.555e-02	0.281	-3.867	TAF11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa	6	-34953532	BQ709323	6882	6p21.31	Hs.112444	30	DNA binding transcription coactivator activity nucleus nucleoplasm transcription factor TFIID complex transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter general RNA polymerase II transcription factor activity vitamin D receptor binding positive regulation by host of viral transcription regulation of transcription thyroid hormone receptor binding protein N-terminus binding	Basal transcription factors
242555_at	-0.295	4.426	-2.306	3.556e-02	0.281	-3.867	C16orf87	chromosome 16 open reading frame 87	16	-45393459	AW578854	388272	16q11.2	Hs.406551	1
201987_at	-0.234	9.704	-2.306	3.556e-02	0.281	-3.867	MED13	mediator complex subunit 13	17	-57374747	AI984051	9969	17q22-q23	Hs.282678	26	receptor activity nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
243550_at	-0.240	2.846	-2.306	3.556e-02	0.281	-3.867	ZDHHC21	zinc finger, DHHC-type containing 21	9	-14607032	AA564788	340481	9p22.3	Hs.649522	4	zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding
212612_at	-0.385	6.994	-2.306	3.556e-02	0.281	-3.867	RCOR1	REST corepressor 1	14	102128985	D31888	23186	14q32.31	Hs.510521	28	DNA binding protein binding nucleus chromatin modification interspecies interaction between organisms regulation of transcription	Huntington's disease
202595_s_at	0.255	6.046	2.306	3.557e-02	0.281	-3.868	LEPROTL1	leptin receptor overlapping transcript-like 1	8	30072463, 30072463	AF161461	23484	8p21.2-p21.1	Hs.146585	8	membrane integral to membrane
205743_at	0.292	6.332	2.306	3.558e-02	0.281	-3.868	STAC	SH3 and cysteine rich domain	3	36397100	NM_003149	6769	3p22.3	Hs.56045	4	soluble fraction cytoplasm intracellular signaling cascade zinc ion binding diacylglycerol binding cellular response to heat metal ion binding
217902_s_at	-0.219	8.060	-2.306	3.559e-02	0.281	-3.868	HERC2	hect domain and RLD 2	15	-26029782	NM_004667	8924	15q13	Hs.434890 Hs.610412	24	ubiquitin-protein ligase activity guanyl-nucleotide exchange factor activity protein binding cellular_component intracellular anaphase-promoting complex protein modification process intracellular protein transport zinc ion binding protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process heme binding regulation of mitotic metaphase/anaphase transition metal ion binding	Ubiquitin mediated proteolysis
235175_at	0.358	4.978	2.306	3.559e-02	0.281	-3.868	GBP4	guanylate binding protein 4	1	-89419418	BG260886	115361	1p22.2	Hs.409925	4	nucleotide binding GTPase activity GTP binding cytoplasm immune response
204001_at	-0.296	6.178	-2.306	3.560e-02	0.281	-3.868	SNAPC3	small nuclear RNA activating complex, polypeptide 3, 50kDa	9	15412781	NM_003084	6619	9p22.3	Hs.546299	12	DNA binding protein binding nucleus transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter snRNA transcription regulation of transcription
1561820_at	-0.288	4.728	-2.306	3.560e-02	0.281	-3.868	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit	12	50271286	BQ337986	6334	12q13	Hs.710638	18	nucleotide binding voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ATP binding ion transport sodium ion transport nervous system development membrane integral to membrane regulation of action potential in neuron sodium ion binding
222414_at	-0.311	7.217	-2.305	3.563e-02	0.281	-3.869	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	7	-151462942	AA121529	58508	7q36.1	Hs.647120	21	DNA binding protein binding nucleus regulation of transcription, DNA-dependent intracellular signaling cascade methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding
1565559_at	0.267	5.365	2.305	3.564e-02	0.281	-3.869	MAGIX	MAGI family member, X-linked	X	48906124, 48907213	AW418579	79917	Xp11.23	Hs.193170	3	protein binding
202301_s_at	-0.392	7.267	-2.305	3.564e-02	0.281	-3.869	RSRC2	arginine/serine-rich coiled-coil 2	12	-121555225, -121555225	BE396879	65117	12q24.31	Hs.432996	4
230839_at	0.190	5.113	2.305	3.565e-02	0.281	-3.869	PRMT8	protein arginine methyltransferase 8	12	3470685	AK026786	56341	12p13.3	Hs.504530	9	nucleus plasma membrane histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity protein homodimerization activity regulation of protein binding protein heterodimerization activity
217994_x_at	-0.246	7.249	-2.305	3.565e-02	0.281	-3.870	CPSF3L	cleavage and polyadenylation specific factor 3-like	1	-1236827	NM_017871	54973	1p36.33	Hs.6449	11	nucleus cytoplasm hydrolase activity
205344_at	0.226	5.517	2.305	3.565e-02	0.281	-3.870	CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	3	-47578731	NM_006574	10675	3p21.3	Hs.45127	9	protein binding protein binding membrane fraction endoplasmic reticulum Golgi apparatus plasma membrane integral to plasma membrane multicellular organismal development nervous system development growth factor activity cell differentiation Golgi-associated vesicle membrane regulation of growth intracellular transport
203321_s_at	0.222	5.599	2.305	3.565e-02	0.281	-3.870	ADNP2	ADNP homeobox 2	18	75967902	AK022688	22850	18q23	Hs.131915	5	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
232692_at	-0.524	4.698	-2.305	3.566e-02	0.281	-3.870	TDRD6	tudor domain containing 6	6	46763824	AA404231	221400	6p12.3	Hs.656983	5	nucleic acid binding
241621_at	-0.282	3.259	-2.305	3.566e-02	0.281	-3.870	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1	18	2645885	AW974517	23347	18p11.32	Hs.8118	6	protein binding ATP binding chromosome chromosome organization
202671_s_at	0.418	6.640	2.305	3.568e-02	0.281	-3.870	PDXK	pyridoxal (pyridoxine, vitamin B6) kinase	21	43963405	NM_003681	8566	21q22.3	Hs.284491	24	nucleotide binding magnesium ion binding ATP binding cytoplasm cytosol zinc ion binding cell proliferation pyridoxal kinase activity pyridoxine biosynthetic process transferase activity pyridoxal phosphate binding potassium ion binding sodium ion binding lithium ion binding protein homodimerization activity vitamin B6 metabolic process pyridoxal phosphate biosynthetic process	Vitamin B6 metabolism Metabolic pathways
214701_s_at	0.250	4.252	2.305	3.568e-02	0.281	-3.870	FN1	fibronectin 1	2	-215987628, -215933423	AJ276395	2335	2q34	Hs.203717	291	extracellular matrix structural constituent collagen binding extracellular region extracellular region fibrinogen complex proteinaceous extracellular matrix ER-Golgi intermediate compartment acute-phase response cell adhesion heparin binding regulation of cell shape response to wounding cell migration peptide cross-linking platelet alpha granule lumen substrate adhesion-dependent cell spreading	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer
216217_at	0.252	5.384	2.304	3.570e-02	0.281	-3.871	PLCL2	phospholipase C-like 2	3	16901455, 16949585	AK023546	23228	3p24.3	Hs.202010	7	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
217073_x_at	0.226	4.189	2.304	3.571e-02	0.281	-3.871	APOA1	apolipoprotein A-I	11	-116211678, 13497	X02162	335	11q23-q24	Hs.633003	424	beta-amyloid binding negative regulation of cytokine secretion during immune response phospholipid binding extracellular region extracellular region endoplasmic reticulum lumen lipid metabolic process phosphatidylcholine biosynthetic process lipid transport G-protein coupled receptor protein signaling pathway steroid metabolic process cholesterol metabolic process positive regulation of cholesterol esterification negative regulation of very-low-density lipoprotein particle remodeling cholesterol binding cholesterol transporter activity cholesterol transporter activity enzyme binding endocytic vesicle cytoplasmic vesicle Cdc42 protein signal transduction cholesterol efflux phospholipid efflux apolipoprotein A-I receptor binding very-low-density lipoprotein particle spherical high-density lipoprotein particle high-density lipoprotein particle assembly high-density lipoprotein particle clearance lipoprotein metabolic process cholesterol homeostasis identical protein binding reverse cholesterol transport negative regulation of interleukin-1 beta secretion protein stabilization positive regulation of hydrolase activity phosphatidylcholine-sterol O-acyltransferase activator activity cholesterol import high-density lipoprotein receptor binding	PPAR signaling pathway
238448_at	0.220	2.945	2.304	3.572e-02	0.281	-3.871	MRPL19	mitochondrial ribosomal protein L19	2	75727416	BE544070	9801	2q11.1-q11.2	Hs.44024	11	structural constituent of ribosome intracellular nucleus mitochondrion ribosome translation nuclear membrane
208208_at	-0.164	5.684	-2.304	3.572e-02	0.281	-3.871	MYH13	myosin, heavy chain 13, skeletal muscle	17	-10144907	NM_003802	8735	17p13	Hs.711142	8	microfilament motor activity nucleotide binding actin binding calmodulin binding ATP binding cytoplasm striated muscle thick filament striated muscle contraction myosin complex myofibril	Tight junction
1561579_at	0.223	4.195	2.304	3.573e-02	0.281	-3.872	LOC728445	hypothetical protein LOC728445	8		AI240136	728445	8p11.21	Hs.713375
1556204_a_at	0.352	4.241	2.304	3.574e-02	0.281	-3.872	ZNF814	zinc finger protein 814	19	-63072558	AK096401	730051	19q13.43	Hs.634143 Hs.669024 Hs.719319	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221667_s_at	-0.401	11.262	-2.304	3.574e-02	0.281	-3.872	HSPB8	heat shock 22kDa protein 8	12	118100977	AF133207	26353	12q24.23	Hs.400095	48	protein serine/threonine kinase activity cellular_component intracellular biological_process cell death response to heat identical protein binding
1553051_s_at	0.189	4.231	2.304	3.574e-02	0.281	-3.872	ODF3	outer dense fiber of sperm tails 3	11	186760	NM_053280	113746	11p15.5	Hs.350949	2	outer dense fiber cytoplasm multicellular organismal development spermatogenesis cell differentiation
225292_at	0.347	5.916	2.304	3.576e-02	0.281	-3.872	COL27A1	collagen, type XXVII, alpha 1	9	115958051	AU145229	85301	9q32	Hs.494892	8	extracellular matrix structural constituent extracellular region collagen cell adhesion
233356_at	0.347	4.637	2.304	3.576e-02	0.281	-3.872	EEF1DP3	eukaryotic translation elongation factor 1 delta pseudogene 3	13	31318919	U50525	196549	13q13.1	Hs.507667	3
244413_at	0.184	3.652	2.304	3.576e-02	0.281	-3.872	CLECL1	C-type lectin-like 1	12	-9766357	AW237307	160365	12p13.31	Hs.560087	3	binding sugar binding plasma membrane integral to membrane
232313_at	0.236	3.693	2.303	3.580e-02	0.281	-3.873	TMEM132C	transmembrane protein 132C	12	127465243	AL122107	92293	12q24.32	Hs.49599		molecular_function cellular_component biological_process membrane integral to membrane
238116_at	0.182	2.408	2.303	3.581e-02	0.281	-3.874	DYNLRB2	dynein, light chain, roadblock-type 2	16	79132354	AW959427	83657	16q23.3	Hs.98849	5	microtubule motor activity protein binding cytoplasm cytoplasmic dynein complex microtubule microtubule-based movement
206806_at	0.171	3.698	2.303	3.582e-02	0.281	-3.874	DGKI	diacylglycerol kinase, iota	7	-136724924	NM_004717	9162	7q32.3-q33	Hs.242947	6	nucleotide binding diacylglycerol kinase activity protein binding ATP binding nucleus cytoplasm activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway intracellular signaling cascade zinc ion binding transferase activity metal ion binding	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phosphatidylinositol signaling system
218736_s_at	-0.366	8.679	-2.303	3.583e-02	0.281	-3.874	PALMD	palmdelphin	1	99884018	NM_017734	54873	1p22-p21	Hs.483993	7	cytoplasm regulation of cell shape membrane
205145_s_at	0.776	5.996	2.302	3.583e-02	0.281	-3.874	MYL5	myosin, light chain 5, regulatory	4	661710	NM_002477	4636	4p16.3	Hs.410970	4	motor activity calcium ion binding muscle myosin complex regulation of muscle contraction structural constituent of muscle myosin complex	Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton
231017_at	-0.428	7.174	-2.302	3.585e-02	0.281	-3.874	STK11	serine/threonine kinase 11	19	1156797	AI914604	6794	19p13.3	Hs.515005	129	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation cell cycle cell cycle arrest negative regulation of cell proliferation transferase activity manganese ion binding	mTOR signaling pathway Adipocytokine signaling pathway
236696_at	-0.426	4.899	-2.302	3.585e-02	0.281	-3.875	SR140	U2-associated SR140 protein	3	144203061	BE464843	23350	3q23	Hs.596572	4	nucleotide binding RNA binding RNA processing
209919_x_at	0.221	5.464	2.302	3.586e-02	0.281	-3.875	GGT1	gamma-glutamyltransferase 1	22	23309717, 23329179, 23333654	L20490	2678	22q11.23	Hs.595809 Hs.645535	71	molecular_function gamma-glutamyltransferase activity protein binding cellular amino acid metabolic process glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity	Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways
202232_s_at	-0.220	9.085	-2.302	3.586e-02	0.281	-3.875	EIF3M	eukaryotic translation initiation factor 3, subunit M	11	32561966	NM_006360	10480	11p13	Hs.502244	13	translation initiation factor activity protein binding cytoplasm eukaryotic translation initiation factor 3 complex translational initiation
221955_at	0.338	5.423	2.302	3.586e-02	0.281	-3.875	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	19	3045407	AI040021	2767	19p13.3	Hs.650575 Hs.654784	44	nucleotide binding skeletal system development regulation of action potential GTPase activity signal transducer activity GTP binding cytoplasm plasma membrane protein amino acid ADP-ribosylation signal transduction G-protein coupled receptor protein signaling pathway heart development guanyl nucleotide binding regulation of melanocyte differentiation pigmentation during development activation of phospholipase C activity by dopamine receptor signaling pathway	Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term depression GnRH signaling pathway
1555741_at	0.218	3.722	2.302	3.587e-02	0.281	-3.875	MRAP	melanocortin 2 receptor accessory protein	21	32585994, 32585994	AF483549	56246	21q22.1	Hs.584940	12	cytoplasm endoplasmic reticulum plasma membrane integral to membrane perinuclear region of cytoplasm
226621_at	0.326	5.909	2.302	3.590e-02	0.281	-3.876	FGG	fibrinogen gamma chain	4	-155745177, -155744735	AI133452	2266	4q28	Hs.546255	157	receptor binding calcium ion binding extracellular region extracellular region fibrinogen complex plasma membrane signal transduction external side of plasma membrane platelet activation protein binding, bridging platelet alpha granule lumen eukaryotic cell surface binding protein polymerization response to calcium ion	Complement and coagulation cascades
234989_at	-0.350	11.936	-2.301	3.590e-02	0.281	-3.876	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AV699657	283131	11q13.1	Hs.523789 Hs.648467	6
203481_at	-0.524	6.363	-2.301	3.591e-02	0.281	-3.876	FAM178A	family with sequence similarity 178, member A	10	102662315, 102662315, 102662315	AI655902	55719	10q24.31	Hs.447458	5
209860_s_at	-0.337	9.710	-2.301	3.593e-02	0.282	-3.876	ANXA7	annexin A7	10	-74805194	J04543	310	10q21.1-q21.2	Hs.631827	24	calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding
225625_at	0.331	6.006	2.301	3.594e-02	0.282	-3.877	ALKBH2	alkB, alkylation repair homolog 2 (E. coli)	12	-108010375	AI865555	121642	12q24.11	Hs.374458	11	damaged DNA binding iron ion binding nucleus nucleoplasm DNA repair response to DNA damage stimulus 2-oxoglutarate-dependent dioxygenase activity oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding DNA demethylase activity oxidation reduction
221656_s_at	-0.258	7.920	-2.301	3.595e-02	0.282	-3.877	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	1	17738916, 17779634	BC003073	55160	1p36.13	Hs.443460	5	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm regulation of Rho protein signal transduction
225903_at	-0.298	6.337	-2.301	3.596e-02	0.282	-3.877	PIGU	phosphatidylinositol glycan anchor biosynthesis, class U	20	-32612006	AL118520	128869	20q11.22	Hs.253319	11	GPI-anchor transamidase activity endoplasmic reticulum endoplasmic reticulum membrane plasma membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein GPI anchor binding GPI-anchor transamidase complex regulation of JAK-STAT cascade	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
225093_at	0.310	7.537	2.300	3.599e-02	0.282	-3.878	UTRN	utrophin	6	144654565	N66570	7402	6q24	Hs.133135	51	actin binding calcium ion binding protein binding membrane fraction cytoplasm cytoskeleton plasma membrane muscle contraction muscle organ development zinc ion binding cell junction synapse postsynaptic membrane
219662_at	-0.388	6.611	-2.300	3.601e-02	0.282	-3.878	C2orf49	chromosome 2 open reading frame 49	2	105320444	NM_024093	79074	2q12.1	Hs.549577	4	molecular_function cellular_component biological_process
205787_x_at	-0.218	5.145	-2.300	3.601e-02	0.282	-3.879	ZC3H11A	zinc finger CCCH-type containing 11A	1	202031373	AI803216	9877	1q32.1	Hs.532399	13	nucleic acid binding protein binding zinc ion binding metal ion binding
202935_s_at	-0.499	4.532	-2.300	3.604e-02	0.282	-3.879	SOX9	SRY (sex determining region Y)-box 9	17	67628755	AI382146	6662	17q24.3-q25.1	Hs.647409	90	cartilage condensation cell fate specification epithelial to mesenchymal transition hair follicle development transcription factor activity specific RNA polymerase II transcription factor activity protein binding nucleus nucleolus heart development male gonad development neural crest cell development transcription activator activity male germ-line sex determination negative regulation of bone mineralization negative regulation of chondrocyte differentiation regulation of cell proliferation regulation of apoptosis sequence-specific DNA binding regulation of transcription negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter endochondral bone morphogenesis
222422_s_at	-0.265	7.071	-2.299	3.605e-02	0.282	-3.879	NDFIP1	Nedd4 family interacting protein 1	5	141468507	AW167859	80762	5q31.3	Hs.653510 Hs.9788	11	signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport
202424_at	-0.294	8.077	-2.299	3.606e-02	0.282	-3.880	MAP2K2	mitogen-activated protein kinase kinase 2	19	-4041319	NM_030662	5605	19p13.3	Hs.465627	98	nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding extracellular region protein amino acid phosphorylation Ras protein signal transduction transferase activity	MAPK signaling pathway ErbB signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Pathways in cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
216961_s_at	0.234	4.867	2.299	3.609e-02	0.282	-3.881	RPAIN	RPA interacting protein	17	5263684, 5263684	M69039	84268	17p13.2	Hs.462086 Hs.555866 Hs.667574	9	nucleus cytoplasm DNA-dependent DNA replication DNA repair DNA recombination protein import into nucleus zinc ion binding response to UV PML body protein complex binding metal ion binding
223714_at	0.838	3.816	2.298	3.612e-02	0.282	-3.881	ZNF256	zinc finger protein 256	19	-63144012	BC001438	10172	19q13.43	Hs.596242	5	transcription factor activity protein binding intracellular nucleus multicellular organismal development zinc ion binding general transcriptional repressor activity regulation of transcription metal ion binding
1561334_at	-0.212	4.519	-2.298	3.612e-02	0.282	-3.881	LOC285181	hypothetical protein LOC285181	2		AA002166	285181	2q36.1	Hs.434525	1
209681_at	-0.904	8.790	-2.298	3.613e-02	0.282	-3.881	SLC19A2	solute carrier family 19 (thiamine transporter), member 2	1	-167699772	AF153330	10560	1q23.3	Hs.30246	32	folic acid binding cytoplasm plasma membrane transport folic acid transporter activity reduced folate carrier activity thiamin transmembrane transporter activity thiamin transport integral to membrane thiamin and derivative metabolic process
203881_s_at	-0.323	10.140	-2.298	3.613e-02	0.282	-3.881	DMD	dystrophin	X	-31106232, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265	NM_004010	1756	Xp21.2	Hs.495912	240	actin binding structural constituent of cytoskeleton calcium ion binding protein binding cytoplasm cytoskeleton muscle organ development zinc ion binding structural constituent of muscle structural constituent of muscle cell surface dystrophin-associated glycoprotein complex sarcolemma costamere peptide biosynthetic process nitric-oxide synthase binding	Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
220550_at	-0.188	2.127	-2.298	3.615e-02	0.283	-3.882	FBXO4	F-box protein 4	5	41961112, 41961112	NM_018007	26272	5p12	Hs.165575	14	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
223532_at	0.264	5.944	2.298	3.617e-02	0.283	-3.882	ANKRD39	ankyrin repeat domain 39	2	-96877450	AF151034	51239	2q11.2	Hs.709507	6
217677_at	0.204	3.047	2.298	3.617e-02	0.283	-3.882	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	8	38877909	BF542055	59339	8p11.22	Hs.369123	4	phospholipid binding phosphatidylinositol binding cellular_component nucleus cytoplasm plasma membrane biological_process
214066_x_at	0.237	5.542	2.298	3.617e-02	0.283	-3.882	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)	9	35782405	AA565715	4882	9p21-p12	Hs.78518	34	nucleotide binding guanylate cyclase activity protein kinase activity transmembrane receptor activity ATP binding GTP binding plasma membrane cGMP biosynthetic process protein amino acid phosphorylation cell surface receptor linked signal transduction intracellular signaling cascade regulation of blood pressure peptide receptor activity, G-protein coupled integral to membrane	Purine metabolism Vascular smooth muscle contraction
225064_at	-0.548	7.984	-2.298	3.618e-02	0.283	-3.883	RABEP1	rabaptin, RAB GTPase binding effector protein 1	17	5126281	R60018	9135	17p13.2	Hs.584784 Hs.592121	19	GTPase activator activity protein binding cytoplasm early endosome endocytosis apoptosis membrane fusion growth factor activity protein transport recycling endosome	Endocytosis
218029_at	0.195	6.302	2.297	3.619e-02	0.283	-3.883	FAM65A	family with sequence similarity 65, member A	16	66120254	NM_024519	79567	16q22.1	Hs.152717	5	binding
223319_at	-0.269	7.040	-2.297	3.621e-02	0.283	-3.883	GPHN	gephyrin	14	66043877	AF272663	10243	14q23.3	Hs.208765	29	nucleotide binding magnesium ion binding catalytic activity protein binding intracellular cytoplasm cytoskeleton plasma membrane Mo-molybdopterin cofactor biosynthetic process establishment of synaptic specificity at neuromuscular junction cell junction synapse postsynaptic membrane
211804_s_at	0.202	3.475	2.297	3.622e-02	0.283	-3.884	CDK2	cyclin-dependent kinase 2	12	54646822	AB012305	1017	12q13	Hs.19192 Hs.689624	306	G2/M transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase activity cyclin-dependent protein kinase activity ATP binding nucleus nucleoplasm cytoplasm cytosol regulation of DNA replication protein amino acid phosphorylation cell cycle mitosis traversing start control point of mitotic cell cycle positive regulation of cell proliferation transferase activity histone kinase activity identical protein binding cell division	Cell cycle p53 signaling pathway Pathways in cancer Prostate cancer Small cell lung cancer
209574_s_at	-0.593	5.782	-2.297	3.624e-02	0.283	-3.884	C18orf1	chromosome 18 open reading frame 1	18	13208785, 13601664, 13610866	AI349506	753	18p11.2	Hs.149363	9	molecular_function plasma membrane biological_process integral to membrane
215945_s_at	0.198	5.131	2.297	3.624e-02	0.283	-3.884	TRIM2	tripartite motif-containing 2	4	154293719, 154345047	BC005016	23321	4q31.3	Hs.435711	6	protein binding intracellular cytoplasm biological_process zinc ion binding metal ion binding
202387_at	0.300	9.456	2.297	3.624e-02	0.283	-3.884	BAG1	BCL2-associated athanogene	9	-33242469	NM_004323	573	9p12	Hs.377484	78	receptor signaling protein activity protein binding nucleus cytoplasm cytoskeleton apoptosis anti-apoptosis cell surface receptor linked signal transduction
240592_at	-0.353	7.375	-2.297	3.625e-02	0.283	-3.884	LCORL	ligand dependent nuclear receptor corepressor-like	4	-17453941	AI939336	254251	4p15.31	Hs.446201 Hs.661849 Hs.677572	9	DNA binding RNA polymerase II transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription
1553640_at	-0.184	5.082	-2.297	3.625e-02	0.283	-3.884	XKR6	XK, Kell blood group complex subunit-related family, member 6	8	-10791066	NM_173683	286046	8p23.1	Hs.657083 Hs.666146	6	membrane integral to membrane
218574_s_at	0.298	10.510	2.296	3.627e-02	0.283	-3.885	LMCD1	LIM and cysteine-rich domains 1	3	8518510	NM_014583	29995	3p26-p24	Hs.475353	4	negative regulation of transcription from RNA polymerase II promoter molecular_function transcription corepressor activity protein binding cellular_component nucleus biological_process zinc ion binding metal ion binding
219102_at	0.160	5.353	2.296	3.627e-02	0.283	-3.885	RCN3	reticulocalbin 3, EF-hand calcium binding domain	19	54722686	NM_020650	57333	19q13.33	Hs.567550	6	calcium ion binding protein binding endoplasmic reticulum endoplasmic reticulum lumen
239265_at	0.418	4.832	2.296	3.628e-02	0.283	-3.885	TMEM20	transmembrane protein 20	10	95643719	R56424	159371	10q23.33	Hs.632085	4	membrane integral to membrane
227132_at	-0.208	5.895	-2.296	3.629e-02	0.283	-3.885	ZNF706	zinc finger protein 706	8	-102278441, -102278441	N38730	51123	8q22.3	Hs.374485	4	intracellular zinc ion binding metal ion binding
213111_at	-0.353	6.482	-2.295	3.632e-02	0.283	-3.886	PIKFYVE	phosphoinositide kinase, FYVE finger containing	2	208839235, 208839235	AB023198	200576	2q34	Hs.173939	25	nucleotide binding protein binding ATP binding endosome receptor-mediated endocytosis intracellular signaling cascade zinc ion binding membrane kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity transferase activity early endosome membrane protein localization in nucleus retrograde transport, endosome to Golgi cellular protein metabolic process membrane raft phosphatidylinositol metabolic process metal ion binding	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system Endocytosis Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
243841_at	-0.227	4.270	-2.295	3.633e-02	0.283	-3.886	SYNE2	spectrin repeat containing, nuclear envelope 2	14	63389435, 63750611, 63752424	BE673396	23224	14q23.2	Hs.525392	24	actin binding nucleus cytoplasm cytoskeleton membrane integral to membrane nuclear membrane
1729_at	0.189	6.190	2.295	3.636e-02	0.283	-3.887	TRADD	TNFRSF1A-associated via death domain	16	-65745589	L41690	8717	16q22	Hs.460996	68	signal transducer activity cytoplasm cytosol cytoskeleton induction of apoptosis signal transduction activation of pro-apoptotic gene products intermediate filament binding kinase binding tumor necrosis factor-mediated signaling pathway identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade receptor complex positive regulation of hair follicle development molecular adaptor activity death domain binding	Apoptosis RIG-I-like receptor signaling pathway Adipocytokine signaling pathway
206246_at	0.166	5.527	2.295	3.637e-02	0.283	-3.887	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	3	-48530120	NM_004567	5210	3p22-p21	Hs.476217	8	nucleotide binding 6-phosphofructo-2-kinase activity 6-phosphofructo-2-kinase activity fructose-2,6-bisphosphate 2-phosphatase activity ATP binding cellular_component cytosol fructose 2,6-bisphosphate metabolic process metabolic process kinase activity transferase activity hydrolase activity	Fructose and mannose metabolism
204975_at	0.294	7.736	2.295	3.637e-02	0.283	-3.887	EMP2	epithelial membrane protein 2	16	-10529780	NM_001424	2013	16p13.2	Hs.531561	17	cell proliferation membrane integral to membrane
1569069_s_at	-0.289	6.322	-2.295	3.637e-02	0.283	-3.887	TDRD3	tudor domain containing 3	13	59868591, 59869427	BC020604	81550	13q21.2	Hs.525061	12	nucleic acid binding nucleus cytoplasm
206070_s_at	0.608	3.534	2.295	3.637e-02	0.283	-3.887	EPHA3	EPH receptor A3	3	89239363, 89239363	AF213459	2042	3p11.2	Hs.123642	35	nucleotide binding receptor activity ephrin receptor activity ATP binding extracellular region plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway transferase activity	Axon guidance
204404_at	-0.525	5.974	-2.295	3.639e-02	0.283	-3.888	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2	5	127447381	NM_001046	6558	5q23.3	Hs.162585 Hs.712970	29	transporter activity membrane fraction integral to plasma membrane ion transport potassium ion transport sodium ion transport sodium:potassium:chloride symporter activity symporter activity membrane transepithelial chloride transport potassium ion binding sodium ion binding ammonia transporter activity transepithelial ammonium transport	Vibrio cholerae infection
1567272_at	0.185	4.037	2.295	3.639e-02	0.283	-3.888	OR2K2	olfactory receptor, family 2, subfamily K, member 2	9	-113129583	X64977	26248	9q31.3	Hs.381312	6	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus	Olfactory transduction
226053_at	-0.328	6.727	-2.295	3.639e-02	0.283	-3.888	MAP2K7	mitogen-activated protein kinase kinase 7	19	7874764	AI090153	5609	19p13.3-p13.2	Hs.531754	46	nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm protein amino acid phosphorylation response to stress signal transduction transferase activity protein kinase binding stress-activated MAPK cascade	MAPK signaling pathway ErbB signaling pathway Toll-like receptor signaling pathway T cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway GnRH signaling pathway
1555719_a_at	0.331	3.147	2.295	3.639e-02	0.283	-3.888	C3orf15	chromosome 3 open reading frame 15	3	120904558	AB063298	89876	3q12-q13.3	Hs.341906	8	protein binding cytoplasm mitochondrion
232269_x_at	-0.236	6.918	-2.294	3.639e-02	0.283	-3.888	METRN	meteorin, glial cell differentiation regulator	16	705173	BE965311	79006	16p13.3	Hs.533772	6	extracellular region extracellular space multicellular organismal development nervous system development glial cell differentiation positive regulation of axonogenesis
201977_s_at	0.362	6.830	2.294	3.640e-02	0.283	-3.888	KIAA0141	KIAA0141	5	141283568	AI539425	9812	5q31.3	Hs.210532	6	binding mitochondrion
205174_s_at	0.938	4.526	2.294	3.640e-02	0.283	-3.888	QPCT	glutaminyl-peptide cyclotransferase	2	37425256	NM_012413	25797	2p22.2	Hs.79033	15	protein modification process proteolysis peptidase activity zinc ion binding acyltransferase activity glutaminyl-peptide cyclotransferase activity transferase activity metal ion binding
220449_at	0.174	5.908	2.294	3.642e-02	0.283	-3.889	MGC5566	hypothetical protein MGC5566	20		NM_024049	79015	20q13.12	Hs.255479	1
210270_at	0.274	4.929	2.294	3.642e-02	0.283	-3.889	RGS6	regulator of G-protein signaling 6	14	71469538	AF156932	9628	14q24.3	Hs.509872	13	signal transducer activity GTPase activator activity cellular_component cytoplasm heterotrimeric G-protein complex intracellular signaling cascade regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction membrane
229266_at	0.289	3.200	2.294	3.644e-02	0.283	-3.889	LOC284033	hypothetical LOC284033	17		AI138603	284033	17p12	Hs.592124	2
202539_s_at	-0.367	5.336	-2.293	3.647e-02	0.283	-3.890	HMGCR	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	5	74668748	AL518627	3156	5q13.3-q14	Hs.643495 Hs.698445 Hs.713530	72	hydroxymethylglutaryl-CoA reductase (NADPH) activity peroxisome endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane cholesterol biosynthetic process isoprenoid biosynthetic process germ cell migration gonad development coenzyme A metabolic process membrane integral to membrane oxidoreductase activity NADP or NADPH binding oxidation reduction	Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
216267_s_at	-0.193	5.867	-2.293	3.648e-02	0.283	-3.890	TMEM115	transmembrane protein 115	3	-50367183	BF034906	11070	3p21.3	Hs.91566	6	molecular_function nucleus Golgi apparatus negative regulation of cell proliferation membrane integral to membrane
210361_s_at	-0.277	6.019	-2.293	3.649e-02	0.283	-3.890	ELF2	E74-like factor 2 (ets domain transcription factor)	4	-140198320, -140198320	AF256223	1998	4q28	Hs.634040	13	transcription factor activity protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter transcription activator activity sequence-specific DNA binding
213799_s_at	0.242	4.622	2.293	3.650e-02	0.283	-3.890	PTPRA	protein tyrosine phosphatase, receptor type, A	20	2792840, 2802141, 2851852	BF740139	5786	20p13	Hs.269577	58	transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid phosphorylation protein amino acid dephosphorylation membrane hydrolase activity
219518_s_at	-0.412	4.389	-2.293	3.650e-02	0.283	-3.891	ELL3	elongation factor RNA polymerase II-like 3	15	-41852089	NM_025165	80237	15q15.3	Hs.706346	5	protein binding nucleus RNA elongation from RNA polymerase II promoter spermatogenesis transcription elongation factor complex positive transcription elongation factor activity RNA polymerase II transcription elongation factor activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter, global
205888_s_at	0.153	3.100	2.293	3.651e-02	0.283	-3.891	JAKMIP2	janus kinase and microtubule interacting protein 2	5	-146950898	AI962693	9832	5q32	Hs.719177	7	Golgi apparatus
206480_at	0.191	4.726	2.293	3.651e-02	0.283	-3.891	LTC4S	leukotriene C4 synthase	5	179153591	NM_000897	4056	5q35	Hs.706741	69	leukotriene-C4 synthase activity protein binding nucleus nuclear envelope endoplasmic reticulum microsome enzyme activator activity lipid binding membrane integral to membrane lyase activity leukotriene biosynthetic process	Arachidonic acid metabolism Metabolic pathways
234292_s_at	0.234	5.204	2.292	3.657e-02	0.284	-3.892	ZNF167	zinc finger protein 167	3	44571716, 44571716	AK022800	55888	3p22.3-p21.1	Hs.529512 Hs.696570	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
210427_x_at	0.495	9.499	2.292	3.657e-02	0.284	-3.892	ANXA2	annexin A2	15	-58426642, -58426641	BC001388	302	15q21-q22	Hs.511605	137	skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm
224534_at	-0.474	3.620	-2.292	3.658e-02	0.284	-3.892	KREMEN1	kringle containing transmembrane protein 1	22	27799065, 27799105	AB059618	83999	22q12.1	Hs.229335	11	molecular_function membrane fraction cell communication membrane integral to membrane Wnt receptor signaling pathway
238153_at	0.182	4.899	2.292	3.659e-02	0.284	-3.893	PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta	4	609362, 636965	AW451980	5158	4p16.3	Hs.623810 Hs.654544	30	signal transduction visual perception phototransduction, visible light detection of light stimulus membrane hydrolase activity 3',5'-cyclic-GMP phosphodiesterase activity response to stimulus
202779_s_at	-0.530	5.832	-2.292	3.660e-02	0.284	-3.893	UBE2S	ubiquitin-conjugating enzyme E2S	19	-60604461	NM_014501	27338	19q13.43	Hs.396393	6	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
227484_at	0.228	3.851	2.292	3.660e-02	0.284	-3.893	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	12	62524807	BF508615	57522	12q14.2	Hs.210751 Hs.593803	8	GTPase activator activity intracellular signal transduction	Axon guidance
210216_x_at	-0.243	7.457	-2.291	3.661e-02	0.284	-3.893	RAD1	RAD1 homolog (S. pombe)	5	-34941124, -34941122	AF084513	5810	5p13.2	Hs.38114	44	cell cycle checkpoint DNA damage checkpoint damaged DNA binding protein binding nucleus DNA replication DNA repair response to DNA damage stimulus meiotic prophase I 3'-5' exonuclease activity 3'-5' exonuclease activity exodeoxyribonuclease III activity hydrolase activity
227990_at	-0.442	7.637	-2.291	3.664e-02	0.284	-3.894	SLU7	SLU7 splicing factor homolog (S. cerevisiae)	5	-159761225	AA843238	10569	5q33.3	Hs.435342	9	alternative nuclear mRNA splicing, via spliceosome second spliceosomal transesterification activity nuclear mRNA 3'-splice site recognition nucleic acid binding nucleus spliceosomal complex cytoplasm mRNA processing zinc ion binding RNA splicing nuclear speck small nuclear ribonucleoprotein complex pre-mRNA 3'-splice site binding metal ion binding
204894_s_at	0.583	5.962	2.291	3.667e-02	0.284	-3.895	AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)	17	38256726	NM_003734	8639	17q21	Hs.198241	39	copper ion binding calcium ion binding protein binding plasma membrane inflammatory response cell adhesion amine oxidase activity amine metabolic process amine metabolic process cell surface integral to membrane oxidoreductase activity protein homodimerization activity quinone binding oxidation reduction	Glycine, serine and threonine metabolism Tyrosine metabolism Phenylalanine metabolism beta-Alanine metabolism Isoquinoline alkaloid biosynthesis Tropane, piperidine and pyridine alkaloid biosynthesis Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways
204829_s_at	0.272	6.447	2.290	3.669e-02	0.284	-3.895	FOLR2	folate receptor 2 (fetal)	11	71605466	NM_000803	2350	11q13.3-q13.5	Hs.433159	24	receptor activity folic acid binding extracellular region membrane fraction plasma membrane folic acid transport anchored to membrane
213201_s_at	0.272	13.412	2.290	3.669e-02	0.284	-3.895	TNNT1	troponin T type 1 (skeletal, slow)	19	-60335972	AJ011712	7138	19q13.4	Hs.631558	29	skeletal muscle contraction protein binding tropomyosin binding troponin complex troponin complex negative regulation of muscle contraction
235521_at	0.310	6.453	2.290	3.669e-02	0.284	-3.895	HOXA3	homeobox A3	7	-27112333, -27112333, -27112333	AW137982	3200	7p15-p14	Hs.659337	18	blood vessel remodeling transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation specification of organ position glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding thymus development organ formation embryonic skeletal system morphogenesis cartilage development parathyroid gland development
208927_at	-0.322	8.448	-2.290	3.672e-02	0.284	-3.896	SPOP	speckle-type POZ protein	17	-45031244	BF673888	8405	17q21.33	Hs.463382 Hs.718421	27	protein binding nucleus mRNA processing modification-dependent protein catabolic process
204385_at	-0.189	5.143	-2.289	3.676e-02	0.284	-3.897	KYNU	kynureninase (L-kynurenine hydrolase)	2	143351664, 143351664	NM_003937	8942	2q22.2	Hs.470126	11	soluble fraction cytoplasm mitochondrion cytosol cytosol tryptophan catabolic process metabolic process NAD biosynthetic process hydrolase activity pyridine nucleotide biosynthetic process quinolinate biosynthetic process pyridoxal phosphate binding kynureninase activity kynureninase activity kynureninase activity response to interferon-gamma response to vitamin B6 protein homodimerization activity anthranilate metabolic process	Tryptophan metabolism Metabolic pathways
1559201_a_at	0.207	5.077	2.289	3.676e-02	0.284	-3.897	OSTF1	osteoclast stimulating factor 1	9	76893217	BU929456	26578	9q13-q21.2	Hs.494192	17	ossification intracellular cytoplasm signal transduction identical protein binding
244506_at	0.242	4.749	2.289	3.677e-02	0.284	-3.897	TMTC1	transmembrane and tetratricopeptide repeat containing 1	12	-29545023	BE297946	83857	12p11.22	Hs.401954	3	binding membrane integral to membrane
219398_at	0.425	5.793	2.289	3.682e-02	0.284	-3.898	CIDEC	cell death-inducing DFFA-like effector c	3	-9883397	NM_022094	63924	3p25.3	Hs.567562 Hs.635072	6	molecular_function protein binding intracellular cytoplasm cytosol apoptosis induction of apoptosis
1554672_at	-0.254	3.467	-2.288	3.682e-02	0.284	-3.898	TTC26	tetratricopeptide repeat domain 26	7	138469029	BC013912	79989	7q34	Hs.644553	3
223235_s_at	0.578	8.220	2.288	3.682e-02	0.284	-3.898	SMOC2	SPARC related modular calcium binding 2	6	168584879	AB014737	64094	6q27	Hs.487200	8	calcium ion binding extracellular region basement membrane signal transduction
222412_s_at	-0.481	7.289	-2.288	3.682e-02	0.284	-3.898	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	3	-157741236	AW150923	6747	3q25.31	Hs.518346	7	signal sequence binding protein binding endoplasmic reticulum translocon complex microsome cotranslational protein targeting to membrane membrane integral to membrane integral to endoplasmic reticulum membrane
211845_at	0.248	5.252	2.288	3.684e-02	0.284	-3.899	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	11	-119050308, -119036912, -119014017	AF110314	5818	11q23.3	Hs.334846	42	extracellular region plasma membrane cell-cell adherens junction immune response homophilic cell adhesion heterophilic cell adhesion coreceptor activity integral to membrane protein homodimerization activity interspecies interaction between organisms entry of virus into host cell cell adhesion molecule binding	Cell adhesion molecules (CAMs) Adherens junction
1568629_s_at	0.230	7.774	2.288	3.684e-02	0.284	-3.899	PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	19	18125015	BC033311	5296	19q13.2-q13.4	Hs.371344	68	protein binding intracellular cytosol phosphoinositide 3-kinase complex signal transduction 1-phosphatidylinositol-3-kinase activity negative regulation of anti-apoptosis phosphoinositide 3-kinase regulator activity	ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer
222240_s_at	0.291	3.875	2.288	3.686e-02	0.284	-3.899	ISYNA1	inositol-3-phosphate synthase 1	19	-18406624	AL137749	51477	19p13.11	Hs.405873	6	inositol-3-phosphate synthase activity binding cytoplasm inositol biosynthetic process metabolic process phospholipid biosynthetic process isomerase activity	Streptomycin biosynthesis Inositol phosphate metabolism Metabolic pathways
233857_s_at	-0.724	7.624	-2.288	3.687e-02	0.284	-3.899	ASB2	ankyrin repeat and SOCS box-containing 2	14	-93470265	AK002049	51676	14q31-q32	Hs.510327	15	intracellular signaling cascade modification-dependent protein catabolic process
208224_at	0.264	6.171	2.288	3.688e-02	0.285	-3.900	HOXB1	homeobox B1	17	-43961805	NM_002144	3211	17q21.3	Hs.99992	23	transcription factor activity nucleus regulation of transcription, DNA-dependent pattern specification process anterior/posterior pattern formation protein domain specific binding rhombomere 4 development rhombomere 5 development facial nerve structural organization facial nucleus development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter anatomical structure formation involved in morphogenesis embryonic skeletal system morphogenesis
229344_x_at	0.328	5.761	2.288	3.689e-02	0.285	-3.900	RIMKLB	ribosomal modification protein rimK-like family member B	12	8741784	AW135012	57494	12p13.31	Hs.504670	4	nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding
221582_at	0.561	5.568	2.287	3.690e-02	0.285	-3.900	HIST3H2A	histone cluster 3, H2a	1	-226711687	BC001193	92815	1q42.13	Hs.26331 Hs.700190	17	nucleosome DNA binding nucleus chromosome nucleosome assembly	Systemic lupus erythematosus
243285_at	0.274	5.617	2.287	3.690e-02	0.285	-3.900	LOC283335	hypothetical protein LOC283335	12		AI201723	283335	12q13.13	Hs.657060	1
235695_at	0.212	4.629	2.287	3.691e-02	0.285	-3.900	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	2	98427752, 98427752	AI051236	3631	2q11.2	Hs.469386	16	signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system
224062_x_at	0.289	5.163	2.287	3.691e-02	0.285	-3.900	KLK4	kallikrein-related peptidase 4	19	-56101419	AF113140	9622	19q13.41	Hs.218366	34	serine-type endopeptidase activity extracellular region proteolysis peptidase activity zinc ion binding metal ion binding
1558128_at	0.240	3.866	2.287	3.691e-02	0.285	-3.900	LOC730202	hypothetical protein LOC730202	14		BC019017	730202	14q32.2	Hs.647565	1
223758_s_at	0.514	6.231	2.287	3.692e-02	0.285	-3.901	GTF2H2	general transcription factor IIH, polypeptide 2, 44kDa	5	-70366706, 68891809, -972814, 350570	BC005345	2966	5q12.2-q13.3	Hs.191356 Hs.655216	52	nucleotide-excision repair, DNA damage removal transcription factor activity nucleus nucleoplasm DNA repair transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter response to DNA damage stimulus translation factor activity, nucleic acid binding zinc ion binding response to UV regulation of transcription metal ion binding protein N-terminus binding	Basal transcription factors Nucleotide excision repair
226259_at	0.359	7.879	2.287	3.694e-02	0.285	-3.901	EXOC6	exocyst complex component 6	10	94584449, 94598204	AL137438	54536	10q23.33	Hs.655657	8	exocyst vesicle docking during exocytosis protein transport
231659_at	0.246	4.652	2.287	3.694e-02	0.285	-3.901	ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	1	43945804	BE327769	6487	1p34.1	Hs.597915	15	extracellular region Golgi apparatus protein amino acid glycosylation N-acetyllactosaminide alpha-2,3-sialyltransferase activity membrane integral to membrane integral to Golgi membrane	Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
221511_x_at	-0.251	7.859	-2.287	3.695e-02	0.285	-3.901	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AB033080	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
235628_x_at	-0.308	5.422	-2.287	3.695e-02	0.285	-3.901	FLJ33630	hypothetical LOC644873	5	-127385142	BG025030	644873	5q23.3	Hs.340623	2
207031_at	-0.192	3.627	-2.286	3.696e-02	0.285	-3.902	NKX3-2	NK3 homeobox 2	4	-13151551	NM_001189	579	4p16.1	Hs.590927	7	transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter determination of left/right symmetry pancreas development middle ear morphogenesis negative regulation of apoptosis sequence-specific DNA binding spleen development organ formation skeletal system morphogenesis embryonic skeletal system development
204741_at	0.231	5.969	2.286	3.696e-02	0.285	-3.902	BICD1	bicaudal D homolog 1 (Drosophila)	12	32151451	NM_001714	636	12p11.2-p11.1	Hs.505202	17	structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis
220706_at	0.180	4.496	2.286	3.697e-02	0.285	-3.902	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	15	-76838599	NM_014272	11173	15q24.2	Hs.16441	5	metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding
226260_x_at	0.190	6.326	2.286	3.697e-02	0.285	-3.902	ZNF358	zinc finger protein 358	19	7487003	BF026472	140467		Hs.133475	5	DNA binding intracellular nucleus zinc ion binding stem cell maintenance neural tube development embryonic forelimb morphogenesis regulation of transcription metal ion binding
239313_at	-0.251	5.369	-2.286	3.697e-02	0.285	-3.902	LOC401320	hypothetical LOC401320	7		AI803568	401320	7p15.1	Hs.561708	2
224761_at	-0.247	9.104	-2.286	3.698e-02	0.285	-3.902	GNA13	guanine nucleotide binding protein (G protein), alpha 13	17	-60435870	AI928136	10672	17q24.3	Hs.515018	57	nucleotide binding patterning of blood vessels in utero embryonic development GTPase activity signal transducer activity protein binding GTP binding cell motion signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade Rho protein signal transduction regulation of cell shape membrane guanyl nucleotide binding cell differentiation platelet activation regulation of cell migration melanosome	Vascular smooth muscle contraction Long-term depression Regulation of actin cytoskeleton
204375_at	0.217	6.014	2.286	3.702e-02	0.285	-3.903	CLSTN3	calsyntenin 3	12	7174233	NM_014718	9746	12p13.31	Hs.535378	7	Golgi membrane calcium ion binding protein binding endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus plasma membrane cell adhesion homophilic cell adhesion integral to membrane postsynaptic membrane
207184_at	0.222	4.361	2.286	3.703e-02	0.285	-3.903	SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	12	-200051	NM_016615	6540	12p13.3	Hs.504398	7	neurotransmitter:sodium symporter activity gamma-aminobutyric acid:sodium symporter activity integral to plasma membrane neurotransmitter transport symporter activity membrane
215358_x_at	0.325	3.830	2.285	3.705e-02	0.285	-3.904	ZNF37B	zinc finger protein 37B (pseudogene)	10	-42328968	AK026980	100129482	10q11.21	Hs.646695 Hs.648656 Hs.650553 Hs.684178	7
1564463_at	0.281	5.465	2.285	3.707e-02	0.285	-3.904	LOC283711	hypothetical protein LOC283711	15		AK093758	283711	15q13.3	Hs.585100	1
228064_at	0.207	6.631	2.285	3.707e-02	0.285	-3.904	C22orf36	chromosome 22 open reading frame 36	22	-23311590	AW006520	388886	22q11.23	Hs.113314	4
205451_at	-0.222	6.230	-2.285	3.707e-02	0.285	-3.904	FOXO4	forkhead box O4	X	70232750	NM_005938	4303	Xq13.1	Hs.584654	42	G1 phase of mitotic cell cycle transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter cell cycle cell cycle arrest mitotic cell cycle G2/M transition DNA damage checkpoint multicellular organismal development muscle organ development transcription factor binding negative regulation of cell proliferation insulin receptor signaling pathway negative regulation of angiogenesis transcription activator activity enzyme binding cell differentiation sequence-specific DNA binding positive regulation of transcription negative regulation of smooth muscle cell differentiation
213914_s_at	0.271	4.721	2.285	3.710e-02	0.285	-3.905	SPTBN1	spectrin, beta, non-erythrocytic 1	2	54536957, 54639034	R85779	6711	2p21	Hs.503178 Hs.705692	46	actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping
202132_at	0.244	5.669	2.285	3.710e-02	0.285	-3.905	WWTR1	WW domain containing transcription regulator 1	3	-150720721	AA081084	25937	3q23-q24	Hs.719249	13	negative regulation of transcription from RNA polymerase II promoter osteoblast differentiation transcription coactivator activity transcription corepressor activity protein binding nucleus transcription factor complex nucleolus cytoplasm regulation of transcription, DNA-dependent transcription regulator activity glomerulus development protein homodimerization activity negative regulation of fat cell differentiation positive regulation of transcription from RNA polymerase II promoter cilium morphogenesis
202017_at	0.433	5.649	2.284	3.711e-02	0.285	-3.905	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	1	224064419, 224079624	NM_000120	2052	1q42.1	Hs.89649	227	epoxide hydrolase activity endoplasmic reticulum microsome response to toxin membrane integral to membrane hydrolase activity aromatic compound catabolic process cis-stilbene-oxide hydrolase activity	Metabolism of xenobiotics by cytochrome P450
1558954_at	0.222	5.816	2.284	3.711e-02	0.285	-3.905	SNORA78	small nucleolar RNA, H/ACA box 78	16	1955185	BC028232	677844	16p13.3	Hs.707294	2
230246_at	0.253	5.517	2.284	3.712e-02	0.285	-3.905	PLAC9	placenta-specific 9	10	81882237	AI275020	219348	10q22.3	Hs.204947	4	extracellular region
236499_at	0.214	5.969	2.284	3.713e-02	0.285	-3.906	C1orf86	chromosome 1 open reading frame 86	1	-2110847	AI911410	199990	1p36.33	Hs.107101 Hs.719244	5
227802_at	-0.275	6.121	-2.284	3.714e-02	0.285	-3.906	RUFY3	RUN and FYVE domain containing 3	4	71789517, 71806559, 71806559	AI075999	22902	4q13.3	Hs.713172	8	multicellular organismal development nervous system development cell differentiation filopodium growth cone negative regulation of axonogenesis
214246_x_at	0.271	7.489	2.284	3.715e-02	0.285	-3.906	MINK1	misshapen-like kinase 1 (zebrafish)	17	4683350	AI859060	50488	17p13.2	Hs.443417	16	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade multicellular organismal development transferase activity
224646_x_at	-1.304	10.172	-2.284	3.716e-02	0.285	-3.906	H19	H19, imprinted maternally expressed transcript (non-protein coding)	11	-1972981	BF569051	283120	11p15.5	Hs.533566	41
1567247_at	-0.264	2.562	-2.284	3.717e-02	0.285	-3.907	OR5H1	olfactory receptor, family 5, subfamily H, member 1	3	99334231	X64988	26341	3q11.2	Hs.537383	1	receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus
36829_at	-0.416	7.455	-2.283	3.718e-02	0.285	-3.907	PER1	period homolog 1 (Drosophila)	17	-7984512	AF022991	5187	17p13.1-p12	Hs.445534	54	signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm entrainment of circadian clock negative regulation of transcription	Circadian rhythm - mammal
1556821_x_at	-0.427	6.788	-2.283	3.718e-02	0.285	-3.907	DLEU2	deleted in lymphocytic leukemia 2 (non-protein coding)	13	-49454688	H48516	8847	13q14.3	Hs.547964	10
202962_at	0.263	5.452	2.283	3.720e-02	0.285	-3.907	KIF13B	kinesin family member 13B	8	-28980713	NM_015254	23303	8p12	Hs.444767	7	nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm cytoskeleton microtubule protein targeting microtubule-based movement signal transduction protein kinase binding T cell activation
229071_at	0.316	4.287	2.283	3.721e-02	0.285	-3.907	C17orf100	chromosome 17 open reading frame 100	17	6495782	AI681419	388327	17p13.1	Hs.262480	2
220195_at	-0.383	6.602	-2.283	3.723e-02	0.285	-3.908	MBD5	methyl-CpG binding domain protein 5	2	148932507	NM_018328	55777	2q23.1	Hs.458312	7	DNA binding nucleus
236563_at	0.238	4.179	2.283	3.724e-02	0.285	-3.908	RD3	retinal degeneration 3	1	-209716486	AA719822	343035	1q32.3	Hs.632495	4	visual perception response to stimulus
89977_at	-0.489	6.465	-2.283	3.724e-02	0.285	-3.908	ACSM5	acyl-CoA synthetase medium-chain family member 5	16	20328356	AI733019	54988	16p12.3	Hs.659606	3	nucleotide binding magnesium ion binding ATP binding GTP binding mitochondrion mitochondrial matrix lipid metabolic process fatty acid metabolic process metabolic process ligase activity butyrate-CoA ligase activity	Butanoate metabolism Metabolic pathways
51158_at	0.216	4.303	2.282	3.725e-02	0.285	-3.908	FAM174B	family with sequence similarity 174, member B	15	-90961682	AI801973	400451	15q26.1	Hs.27373 Hs.702316	2	membrane integral to membrane
239403_at	0.210	4.096	2.282	3.725e-02	0.285	-3.908	CCDC120	coiled-coil domain containing 120	X	48803459, 48803459, 48803466	AI668708	90060	Xp11.23	Hs.522643	6	protein binding
216620_s_at	0.203	5.850	2.282	3.726e-02	0.285	-3.909	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10	8	1759555	AF009205	9639	8p23	Hs.98594	9	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular regulation of Rho protein signal transduction
221863_at	0.208	5.125	2.282	3.726e-02	0.285	-3.909	MIER2	mesoderm induction early response 1, family member 2	19	-256574	AW003889	54531	19p13.3	Hs.101891	2
205805_s_at	0.329	3.580	2.282	3.731e-02	0.286	-3.910	ROR1	receptor tyrosine kinase-like orphan receptor 1	1	64012277, 64012277	NM_005012	4919	1p32-p31	Hs.654491	13	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding cytoplasm plasma membrane integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway transferase activity
201012_at	0.682	7.340	2.281	3.734e-02	0.286	-3.911	ANXA1	annexin A1	9	74956600	NM_000700	301	9q12-q21.2	Hs.494173	90	cornified envelope receptor binding structural molecule activity calcium ion binding calcium-dependent phospholipid binding nucleus cytoplasm cilium lipid metabolic process anti-apoptosis cell motion inflammatory response cell cycle cell surface receptor linked signal transduction basolateral plasma membrane peptide cross-linking phospholipase A2 inhibitor activity keratinocyte differentiation protein binding, bridging regulation of cell proliferation sarcolemma arachidonic acid secretion
200087_s_at	-0.406	9.470	-2.281	3.735e-02	0.286	-3.911	TMED2	transmembrane emp24 domain trafficking protein 2	12	122635028	AK024976	10959	12q24.31	Hs.592682 Hs.75914	10	protein binding microsome ER-Golgi intermediate compartment Golgi apparatus protein transport membrane integral to membrane vesicle-mediated transport cytoplasmic vesicle zymogen granule membrane
227962_at	-0.279	7.234	-2.281	3.736e-02	0.286	-3.911	ACOX1	acyl-Coenzyme A oxidase 1, palmitoyl	17	-71449186	BF435852	51	17q24-q25 17q25.1	Hs.464137	26	acyl-CoA dehydrogenase activity acyl-CoA oxidase activity acyl-CoA oxidase activity cytoplasm mitochondrion peroxisome peroxisomal membrane generation of precursor metabolites and energy lipid metabolic process fatty acid beta-oxidation prostaglandin metabolic process spermatogenesis electron carrier activity protein N-terminus binding FAD binding oxidation reduction	Fatty acid metabolism alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway
1557523_at	0.295	3.764	2.281	3.737e-02	0.286	-3.911	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	5	81636921	AW269750	92270	5q14.2	Hs.364045	2	ATP synthesis coupled proton transport membrane integral to membrane proton-transporting V-type ATPase, V1 domain hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism
208550_x_at	0.246	5.423	2.280	3.744e-02	0.286	-3.913	KCNG2	potassium voltage-gated channel, subfamily G, member 2	18	75724655	NM_012283	26251	18q22-q23	Hs.247905	2	voltage-gated ion channel activity delayed rectifier potassium channel activity protein binding ion transport potassium ion transport regulation of heart contraction voltage-gated potassium channel complex membrane integral to membrane potassium ion binding
223160_s_at	-0.246	6.532	-2.280	3.744e-02	0.286	-3.913	SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	14	-90993708	AK024297	55671	14q32.12	Hs.533887	9	protein binding nucleus cytoplasm centrosome
219798_s_at	-0.231	7.338	-2.280	3.744e-02	0.286	-3.913	MEPCE	methylphosphate capping enzyme	7	99865464	NM_019606	56257	7q22.1	Hs.178011	6	methyltransferase activity transferase activity
218286_s_at	-0.298	8.832	-2.280	3.745e-02	0.286	-3.913	RNF7	ring finger protein 7	3	142939740	NM_014245	9616	3q22-q24	Hs.134623	25	copper ion binding protein binding nucleus cytoplasm anti-apoptosis redox signal response zinc ion binding induction of apoptosis by oxidative stress NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation metal ion binding	Ubiquitin mediated proteolysis
227904_at	0.408	4.367	2.280	3.745e-02	0.286	-3.913	AZI2	5-azacytidine induced 2	3	-28348183, -28338850	BF000175	64343	3p24.1	Hs.706676	12	cytoplasm	RIG-I-like receptor signaling pathway
206068_s_at	0.516	5.677	2.280	3.745e-02	0.286	-3.913	ACADL	acyl-Coenzyme A dehydrogenase, long chain	2	-210760960	AI367275	33	2q34-q35	Hs.471277	14	long-chain-acyl-CoA dehydrogenase activity cytoplasm mitochondrion mitochondrial matrix lipid metabolic process fatty acid metabolic process electron carrier activity FAD binding oxidation reduction	Fatty acid metabolism Metabolic pathways PPAR signaling pathway
211990_at	1.004	9.014	2.280	3.746e-02	0.286	-3.913	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	6	-33140771, -4413300, -4219191	M27487	3113	6p21.3	Hs.347270	71	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II plasma membrane integral to plasma membrane immune response MHC class II receptor activity MHC class II protein complex	Cell adhesion molecules (CAMs) Antigen processing and presentation Type I diabetes mellitus Asthma Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
240891_at	-0.298	4.464	-2.279	3.747e-02	0.286	-3.914	FSTL1	follistatin-like 1	3	-121595751	AW613929	11167	3q13.33	Hs.269512	17	calcium ion binding extracellular region extracellular region extracellular space heparin binding BMP signaling pathway
225391_at	-0.394	6.747	-2.279	3.751e-02	0.286	-3.914	LOC93622	hypothetical LOC93622	4		AL562398	93622	4p16.1	Hs.705429	1
205588_s_at	0.345	4.110	2.279	3.751e-02	0.286	-3.915	FGFR1OP	FGFR1 oncogene partner	6	167332805	NM_007045	11116	6q27	Hs.487175	14	centrosome positive regulation of cell proliferation microtubule anchoring
203116_s_at	-0.190	7.941	-2.279	3.751e-02	0.286	-3.915	FECH	ferrochelatase (protoporphyria)	18	-53363070	NM_000140	2235	18q21.3	Hs.365365	61	ferrochelatase activity ferrochelatase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix generation of precursor metabolites and energy heme biosynthetic process ferrous iron binding response to light stimulus detection of UV membrane protoporphyrinogen IX metabolic process metal ion binding 2 iron, 2 sulfur cluster binding	Porphyrin and chlorophyll metabolism Metabolic pathways
213457_at	0.475	4.635	2.279	3.752e-02	0.286	-3.915	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	8	-8679408	BF739959	9258	8p23.1	Hs.379414	6	protein binding
201712_s_at	-0.283	6.737	-2.279	3.752e-02	0.286	-3.915	RANBP2	RAN binding protein 2	2	108702368	NM_006267	5903	2q12.3	Hs.199561 Hs.715056	61	peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport
225986_x_at	-0.396	7.673	-2.279	3.752e-02	0.286	-3.915	CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	14	91658081	AB037788	53981	14q31.1	Hs.657632	24	nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus hydrolase activity
229382_at	0.324	6.212	2.278	3.756e-02	0.286	-3.916	C1orf183	chromosome 1 open reading frame 183	1	-112069892, -112069892	AW149270	55924	1p13.2	Hs.193406 Hs.657857	3
221534_at	-0.217	7.863	-2.278	3.757e-02	0.286	-3.916	C11orf68	chromosome 11 open reading frame 68	11	-65440859	AF073483	83638	11q13.1	Hs.433573	6
231882_at	-0.245	5.891	-2.278	3.758e-02	0.286	-3.916	FLJ39632	hypothetical LOC642477	14		AL530703	642477	14q11.2	Hs.536395 Hs.647538	2
207643_s_at	-0.244	6.990	-2.278	3.758e-02	0.286	-3.916	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	12	-6308183	NM_001065	7132	12p13.2	Hs.279594 Hs.713833	271	receptor activity tumor necrosis factor receptor activity protein binding extracellular region plasma membrane plasma membrane integral to plasma membrane prostaglandin metabolic process apoptosis signal transduction cytokine-mediated signaling pathway positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms membrane raft positive regulation of transcription from RNA polymerase II promoter positive regulation of inflammatory response	MAPK signaling pathway Cytokine-cytokine receptor interaction Apoptosis Adipocytokine signaling pathway Alzheimer's disease Amyotrophic lateral sclerosis (ALS)
243259_at	-0.302	5.556	-2.278	3.758e-02	0.286	-3.916	ATXN7	ataxin 7	3	63825272	AW081604	6314	3p21.1-p12	Hs.476595	37	protein binding intracellular nucleus nucleolus cytoplasm nucleus organization visual perception cell death zinc ion binding nuclear matrix histone deubiquitination regulation of transcription
219127_at	0.244	4.213	2.278	3.758e-02	0.286	-3.916	ATAD4	ATPase family, AAA domain containing 4	17	-43384332	NM_024320	79170	17q21.32	Hs.368260	1
231559_at	0.337	3.719	2.277	3.762e-02	0.286	-3.917	NNMT	nicotinamide N-methyltransferase	11	113671744	AV650983	4837	11q23.1	Hs.503911	31	cytoplasm nicotinamide N-methyltransferase activity methyltransferase activity transferase activity	Nicotinate and nicotinamide metabolism Metabolic pathways
223350_x_at	-0.277	7.285	-2.277	3.763e-02	0.287	-3.917	LIN7C	lin-7 homolog C (C. elegans)	11	-27472546	N63709	55327	11p14	Hs.693840 Hs.91393	16	protein binding plasma membrane tight junction exocytosis neurotransmitter secretion protein transport synaptosome cell junction synapse postsynaptic membrane
229411_at	0.227	5.635	2.277	3.765e-02	0.287	-3.918	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase	X	-152588383, -152588383	AI986390	139728	Xq28	Hs.436667	6	nucleotide binding calmodulin-dependent protein kinase activity calcium ion binding calmodulin binding ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity
1558628_at	0.237	3.005	2.277	3.766e-02	0.287	-3.918	C18orf22	chromosome 18 open reading frame 22	18	75895345	BC016878	79863	18q23	Hs.593610	3	mitochondrion rRNA processing
201986_at	-0.305	8.281	-2.277	3.766e-02	0.287	-3.918	MED13	mediator complex subunit 13	17	-57374747	AB011165	9969	17q22-q23	Hs.282678	26	receptor activity nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding
222566_at	-0.297	5.985	-2.277	3.768e-02	0.287	-3.919	SUV420H1	suppressor of variegation 4-20 homolog 1 (Drosophila)	11	-67689761, -67680082	AA056099	51111	11q13.2	Hs.632120	11	protein binding nucleus chromosome methyltransferase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription	Lysine degradation
201179_s_at	0.226	6.136	2.276	3.769e-02	0.287	-3.919	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	1	109892708	J03005	2773	1p13	Hs.73799	54	nucleotide binding GTPase activity signal transducer activity protein binding GTP binding cytoplasm Golgi apparatus transport signal transduction G-protein coupled receptor protein signaling pathway negative regulation of adenylate cyclase activity guanyl nucleotide binding	Chemokine signaling pathway Axon guidance Tight junction Gap junction Leukocyte transendothelial migration Long-term depression Melanogenesis
1560133_at	-0.293	3.194	-2.276	3.770e-02	0.287	-3.919	GIGYF2	GRB10 interacting GYF protein 2	2	233270258	BC012484	26058	2q37.1	Hs.565319	23	protein binding
1556096_s_at	-1.454	5.498	-2.276	3.772e-02	0.287	-3.920	UNC13C	unc-13 homolog C (C. elegans)	15	52092392	AL834407	440279	15q21.3	Hs.657273	4	cytoplasm plasma membrane exocytosis intracellular signaling cascade synaptic transmission zinc ion binding diacylglycerol binding cell junction synapse metal ion binding
210331_at	0.187	4.914	2.276	3.773e-02	0.287	-3.920	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	7	43118722	AB048365	23072	7p14.1-p13	Hs.164453	8	protein binding intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process
1557079_at	0.325	2.395	2.276	3.775e-02	0.287	-3.920	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	13	100902966	AI753143	9358	13q33	Hs.696554	5	receptor activity binding extracellular region cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex
230718_at	0.234	3.357	2.275	3.777e-02	0.287	-3.921	HSF5	heat shock transcription factor family member 5	17	-53852527	AL137385	124535	17q22	Hs.380061	1	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
226950_at	0.307	5.333	2.275	3.779e-02	0.287	-3.921	ACVRL1	activin A receptor type II-like 1	12	50587468, 50592379	T63524	94	12q11-q14	Hs.591026	75	nucleotide binding magnesium ion binding angiogenesis in utero embryonic development receptor activity ATP binding cytoplasm plasma membrane integral to plasma membrane protein amino acid phosphorylation negative regulation of cell adhesion signal transduction transforming growth factor beta receptor signaling pathway regulation of blood pressure negative regulation of cell proliferation cell surface negative regulation of endothelial cell migration activin receptor activity, type I transferase activity manganese ion binding negative regulation of cell growth positive regulation of BMP signaling pathway wound healing, spreading of epidermal cells positive regulation of transcription SMAD binding activin binding transforming growth factor beta binding negative regulation of focal adhesion formation	Cytokine-cytokine receptor interaction TGF-beta signaling pathway
208462_s_at	-0.290	5.207	-2.275	3.779e-02	0.287	-3.921	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	12	-21849374, -21841590	NM_005691	10060	12p12.1	Hs.446050	35	nucleotide binding receptor activity transporter activity ATP binding transport sulfonylurea receptor activity ATP-sensitive potassium channel complex potassium ion import potassium channel regulator activity membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances defense response to virus	ABC transporters
223077_at	0.303	4.823	2.274	3.785e-02	0.288	-3.923	TMOD3	tropomodulin 3 (ubiquitous)	15	49909180	AW576360	29766	15q21.1-q21.2	Hs.4998	9	actin binding tropomyosin binding cytoplasm cytoskeleton
201870_at	-0.265	6.403	-2.274	3.786e-02	0.288	-3.923	TOMM34	translocase of outer mitochondrial membrane 34	20	-43004184	NM_006809	10953		Hs.517066	13	signal sequence binding binding cytoplasm mitochondrion mitochondrial outer membrane protein targeting to mitochondrion membrane integral to membrane heat shock protein binding
203516_at	-0.423	8.015	-2.274	3.787e-02	0.288	-3.923	SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	20	-31459423	NM_003098	6640	20q11.2	Hs.31121	36	actin binding calcium ion binding calmodulin binding cytoplasm cytoskeleton muscle contraction neuromuscular junction development cell junction PDZ domain binding sarcolemma postsynaptic membrane
240889_at	0.228	4.479	2.274	3.787e-02	0.288	-3.923	CDRT15L2	CMT1A duplicated region transcript 15-like 2	17		AA446207	256223	17p11.2	Hs.131916	1
228197_at	0.186	5.634	2.274	3.788e-02	0.288	-3.923	C1orf86	chromosome 1 open reading frame 86	1	-2110847	BG030616	199990	1p36.33	Hs.107101 Hs.719244	5
221523_s_at	-0.324	9.420	-2.274	3.788e-02	0.288	-3.923	RRAGD	Ras-related GTP binding D	6	-90131055	AL138717	58528	6q15-q16	Hs.31712	7	nucleotide binding protein binding GTP binding nucleus cytoplasm protein heterodimerization activity
208093_s_at	-0.247	7.737	-2.274	3.788e-02	0.288	-3.923	NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	17	8279903	NM_030808	81565	17p13.1	Hs.372123	38	condensed chromosome kinetochore protein binding cytoplasm centrosome spindle cytoskeleton microtubule transport chromosome segregation multicellular organismal development nervous system development cell differentiation
203467_at	0.194	6.198	2.274	3.789e-02	0.288	-3.923	PMM1	phosphomannomutase 1	22	-40302835	NM_002676	5372	22q13.2	Hs.75835	18	phosphomannomutase activity cytoplasm metabolic process isomerase activity mannose biosynthetic process	Fructose and mannose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways
209894_at	0.708	5.404	2.274	3.790e-02	0.288	-3.924	LEPR	leptin receptor	1	65658905, 65658905, 65658905	U50748	3953	1p31	Hs.705413	260	angiogenesis ovulation from ovarian follicle cytokine receptor activity protein binding extracellular region extracellular space plasma membrane energy reserve metabolic process cell surface receptor linked signal transduction multicellular organismal development female pregnancy cholesterol metabolic process integral to membrane protein-hormone receptor activity peptide hormone binding cellular response to nutrient levels response to nicotine response to chemical stimulus eating behavior response to estrogen stimulus negative regulation of hydrolase activity	Cytokine-cytokine receptor interaction Neuroactive ligand-receptor interaction Jak-STAT signaling pathway Adipocytokine signaling pathway
205503_at	-0.219	3.973	-2.274	3.790e-02	0.288	-3.924	PTPN14	protein tyrosine phosphatase, non-receptor type 14	1	-212597633	NM_005401	5784	1q32.2	Hs.696573	13	protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity
1552819_at	0.312	5.172	2.273	3.790e-02	0.288	-3.924	C21orf86	chromosome 21 open reading frame 86	21		NM_153454	257103	21q22.3	Hs.710382	2
221746_at	-0.203	7.837	-2.273	3.794e-02	0.288	-3.925	UBL4A	ubiquitin-like 4A	X	-153365249	BE543027	8266	Xq28	Hs.76480	9	protein modification process small conjugating protein ligase activity
204562_at	0.258	5.333	2.273	3.794e-02	0.288	-3.925	IRF4	interferon regulatory factor 4	6	336751	NM_002460	3662	6p25-p23	Hs.401013	46	nuclear nucleosome transcription factor activity RNA polymerase II transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription factor binding positive regulation of specific transcription from RNA polymerase II promoter transcription activator activity T cell activation myeloid dendritic cell differentiation positive regulation of DNA binding histone H3 acetylation histone H4 acetylation positive regulation of interleukin-10 biosynthetic process positive regulation of interleukin-2 biosynthetic process positive regulation of interleukin-13 biosynthetic process positive regulation of interleukin-4 biosynthetic process regulation of T-helper cell differentiation positive regulation of transcription
34187_at	0.223	4.009	2.273	3.794e-02	0.288	-3.925	RBMS2	RNA binding motif, single stranded interacting protein 2	12	55201875	D28483	5939	12q13.3	Hs.505729 Hs.683360	7	nucleotide binding RNA binding nucleus RNA processing
202772_at	0.209	8.594	2.273	3.795e-02	0.288	-3.925	HMGCL	3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase	1	-24000953	NM_000191	3155	1p36.1-p35	Hs.533444 Hs.603409	25	hydroxymethylglutaryl-CoA lyase activity hydroxymethylglutaryl-CoA lyase activity mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix metabolic process lyase activity metal ion binding	Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Metabolic pathways
229222_at	0.408	6.266	2.273	3.795e-02	0.288	-3.925	ACSS3	acyl-CoA synthetase short-chain family member 3	12	79995939	AI123815	79611	12q21.31	Hs.259559	2	nucleotide binding acetate-CoA ligase activity ATP binding mitochondrion metabolic process ligase activity	Propanoate metabolism Metabolic pathways
222815_at	-0.321	4.330	-2.273	3.796e-02	0.288	-3.925	RLIM	ring finger protein, LIM domain interacting	X	-73719537	BE966018	51132	Xq13-q21	Hs.653288	9	transcription corepressor activity ubiquitin-protein ligase activity protein binding zinc ion binding negative regulation of transcription ligase activity transcriptional repressor complex modification-dependent protein catabolic process metal ion binding
207901_at	-0.218	2.040	-2.273	3.797e-02	0.288	-3.925	IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	5	-158674368	NM_002187	3593	5q31.1-q33.1	Hs.674	222	natural killer cell activation during immune response positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target signal transducer activity cytokine receptor activity cytokine activity interleukin-12 receptor binding protein binding extracellular region cell cycle arrest cell surface receptor linked signal transduction response to UV-B membrane cell migration sensory perception of pain positive regulation of interferon-gamma production positive regulation of natural killer cell activation positive regulation of smooth muscle cell apoptosis regulation of cytokine biosynthetic process T-helper 1 type immune response T-helper cell differentiation positive regulation of activated T cell proliferation interleukin-12 alpha subunit binding protein homodimerization activity interleukin-12 complex positive regulation of interferon-gamma biosynthetic process positive regulation of cell adhesion protein heterodimerization activity negative regulation of smooth muscle cell proliferation	Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Jak-STAT signaling pathway Type I diabetes mellitus Allograft rejection
216994_s_at	0.229	4.688	2.272	3.798e-02	0.288	-3.926	RUNX2	runt-related transcription factor 2	6	45404031, 45497891	L40992	860	6p21	Hs.535845	152	osteoblast differentiation transcription factor activity RNA polymerase II transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent negative regulation of transcription transcription activator activity
214482_at	-0.256	5.218	-2.272	3.798e-02	0.288	-3.926	ZBTB25	zinc finger and BTB domain containing 25	14	-64023307	NM_006977	7597	14q23-q24	Hs.654571	6	transcription factor activity protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
203771_s_at	0.321	6.944	2.272	3.799e-02	0.288	-3.926	BLVRA	biliverdin reductase A	7	43764796	AA740186	644	7p14-cen	Hs.488143	17	biliverdin reductase activity binding cytoplasm zinc ion binding oxidoreductase activity heme catabolic process metal ion binding oxidation reduction	Porphyrin and chlorophyll metabolism
202609_at	0.340	7.551	2.272	3.800e-02	0.288	-3.926	EPS8	epidermal growth factor receptor pathway substrate 8	12	-15664342	NM_004447	2059	12q13	Hs.591160	35	SH3/SH2 adaptor activity protein binding signal transduction epidermal growth factor receptor signaling pathway cell proliferation adult locomotory behavior postsynaptic density N-methyl-D-aspartate selective glutamate receptor complex synaptosome actin cytoskeleton reorganization behavioral response to ethanol
211535_s_at	0.272	7.168	2.272	3.802e-02	0.288	-3.926	FGFR1	fibroblast growth factor receptor 1	8	-38400008, -38387812	M60485	2260	8p11.2-p11.1	Hs.264887	187	MAPKKK cascade nucleotide binding skeletal system development receptor activity fibroblast growth factor receptor activity fibroblast growth factor receptor activity protein binding ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation heparin binding fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway cell growth transferase activity	MAPK signaling pathway Adherens junction Regulation of actin cytoskeleton Pathways in cancer Prostate cancer Melanoma
232156_at	-0.472	5.818	-2.272	3.803e-02	0.288	-3.927	MUDENG	MU-2/AP1M2 domain containing, death-inducing	14	56805358	AK024921	55745	14q22.3	Hs.597349	9	protein binding intracellular protein transport vesicle-mediated transport clathrin adaptor complex
239111_at	0.246	5.197	2.272	3.805e-02	0.288	-3.927	PRDM8	PR domain containing 8	4	81325447, 81337680	AI077328	56978	4q21	Hs.373642	4	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
224504_s_at	-0.197	6.374	-2.271	3.805e-02	0.288	-3.927	BUD13	BUD13 homolog (S. cerevisiae)	11	-116124097	BC006350	84811	11q23.3	Hs.437341	9
232192_at	0.256	5.032	2.271	3.806e-02	0.288	-3.927	LOC153811	hypothetical protein LOC153811	5		AU145402	153811	5q35.3	Hs.144515	1
201511_at	-0.181	7.540	-2.271	3.808e-02	0.288	-3.928	AAMP	angio-associated, migratory cell protein	2	-218837095	NM_001087	14	2q35	Hs.83347	11	angiogenesis cytoplasm plasma membrane multicellular organismal development heparin binding cell surface positive regulation of endothelial cell migration smooth muscle cell migration cell differentiation
243365_s_at	0.296	4.261	2.271	3.809e-02	0.288	-3.928	AUTS2	autism susceptibility candidate 2	7	68701840, 68701841, 68701841	AI417756	26053	7q11.22	Hs.654801 Hs.712991	13	molecular_function cellular_component biological_process
217739_s_at	-0.479	8.363	-2.271	3.810e-02	0.288	-3.928	NAMPT	nicotinamide phosphoribosyltransferase	7	-105675967	NM_005746	10135	7q22.3	Hs.489615	98	cytokine activity cytoplasm cytosol signal transduction cell-cell signaling positive regulation of cell proliferation NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity	Nicotinate and nicotinamide metabolism
231228_at	0.241	5.642	2.270	3.813e-02	0.288	-3.929	BCL2L1	BCL2-like 1	20	-29715921	AW263226	598	20q11.21	Hs.516966	295	release of cytochrome c from mitochondria nucleus mitochondrion mitochondrial outer membrane mitochondrial outer membrane anti-apoptosis negative regulation of survival gene product expression membrane integral to membrane response to cytokine stimulus identical protein binding regulation of mitochondrial membrane permeability regulation of mitochondrial membrane potential	Apoptosis Jak-STAT signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Pancreatic cancer Chronic myeloid leukemia Small cell lung cancer
218655_s_at	-0.244	6.161	-2.270	3.815e-02	0.288	-3.929	CCDC49	coiled-coil domain containing 49	17	-34210971	NM_017748	54883	17q12	Hs.406223	3
1554206_at	-0.424	5.100	-2.270	3.815e-02	0.288	-3.930	TMLHE	trimethyllysine hydroxylase, epsilon	X	-154372966	BC025269	55217	Xq28	Hs.133321	12	iron ion binding mitochondrion mitochondrial matrix mitochondrial matrix electron carrier activity oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding carnitine biosynthetic process trimethyllysine dioxygenase activity oxidation reduction	Lysine degradation
217176_s_at	-0.349	2.956	-2.269	3.822e-02	0.289	-3.931	ZFX	zinc finger protein, X-linked	X	24079728	X59740	7543	Xp21.3	Hs.336681	13	DNA binding transcription coactivator activity intracellular nucleus nucleolus zinc ion binding transcription regulator activity regulation of transcription metal ion binding
226967_at	0.234	6.463	2.269	3.822e-02	0.289	-3.931	FIZ1	FLT3-interacting zinc finger 1	19	-60794548	BG231981	84922	19q13.42	Hs.515617	5	nucleic acid binding receptor binding intracellular nucleus cytoplasm zinc ion binding protein kinase binding regulation of transcription metal ion binding
225864_at	0.423	5.364	2.269	3.822e-02	0.289	-3.931	FAM84B	family with sequence similarity 84, member B	8	-127633868	AL039862	157638	8q24.21	Hs.124951	5	protein binding cytoplasm plasma membrane
232281_at	0.228	5.756	2.269	3.824e-02	0.289	-3.932	LOC148189	hypothetical LOC148189	19	-32973241	AU147637	148189	19q11	Hs.565253	2
218189_s_at	0.459	6.297	2.269	3.824e-02	0.289	-3.932	NANS	N-acetylneuraminic acid synthase	9	99858779	NM_018946	54187	9p24.1-p23	Hs.522310 Hs.665191	9	cytoplasm cytosol metabolic process N-acylneuraminate cytidylyltransferase activity lipopolysaccharide biosynthetic process carbohydrate biosynthetic process transferase activity N-acetylneuraminic acid phosphate synthase activity N-acylneuraminate-9-phosphate synthase activity N-acetylneuraminate synthase activity	Amino sugar and nucleotide sugar metabolism Metabolic pathways
224345_x_at	0.267	10.762	2.269	3.826e-02	0.289	-3.932	FAM162A	family with sequence similarity 162, member A	3	123585712	AF107495	26355	3q21.1	Hs.584881	8	membrane integral to membrane
210872_x_at	0.263	4.638	2.269	3.826e-02	0.289	-3.932	GAS7	growth arrest-specific 7	17	-9754650, -9754650, -9754650, -9754650	BC001152	8522	17p13.1	Hs.462214	11	transcription factor activity protein binding cytoplasm cell cycle arrest multicellular organismal development nervous system development cell differentiation
203037_s_at	0.367	8.141	2.268	3.829e-02	0.289	-3.933	MTSS1	metastasis suppressor 1	8	-125632208	NM_014751	9788	8p22	Hs.336994 Hs.700429	19	ruffle actin monomer binding receptor binding cytoplasm cell motion cell adhesion signal transduction transmembrane receptor protein tyrosine kinase signaling pathway cytoskeletal adaptor activity actin cytoskeleton SH3 domain binding actin cytoskeleton organization endocytic vesicle filopodium assembly
209315_at	-0.687	5.764	-2.268	3.831e-02	0.289	-3.933	HBS1L	HBS1-like (S. cerevisiae)	6	-135398687, -135323215, -135323213	AW297143	10767	6q23-q24	Hs.378532	12	nucleotide binding translation elongation factor activity GTPase activity GTP binding translation signal transduction
212179_at	-0.376	8.318	-2.268	3.832e-02	0.289	-3.933	SFRS18	splicing factor, arginine/serine-rich 18	6	-99954561	AW157501	25957	6q16.3	Hs.520287	8	nucleus nuclear speck
218432_at	-0.494	9.712	-2.268	3.834e-02	0.289	-3.934	FBXO3	F-box protein 3	11	-33724866, -33719065	NM_012175	26273	11p13	Hs.406787	8	ubiquitin-protein ligase activity proteolysis modification-dependent protein catabolic process
235240_at	-0.289	5.091	-2.267	3.836e-02	0.289	-3.934	ATXN3	ataxin 3	14	-91594648	N51479	4287	14q24.3-q32.2	Hs.532632	98	protein binding nucleus nucleoplasm cytoplasm nucleotide-excision repair synaptic transmission nervous system development cell death nuclear matrix hydrolase activity regulation of transcription
1553148_a_at	-0.455	5.267	-2.267	3.836e-02	0.289	-3.934	SNX13	sorting nexin 13	7	-17796910	R75838	23161	7p21.1	Hs.487648	10	signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding
234925_at	-0.191	3.471	-2.267	3.837e-02	0.289	-3.935	LOC732275	similar to hCG1645603	16	-84922956	AL137562	732275	16q24.1	Hs.558087 Hs.652773 Hs.716963	2
210247_at	0.388	4.790	2.267	3.837e-02	0.289	-3.935	SYN2	synapsin II	3	12020861, 12020861	AW139618	6854	3p25	Hs.445503	22	catalytic activity protein binding ATP binding synaptic transmission neurotransmitter secretion cell junction synaptic vesicle membrane synapse
219431_at	-0.227	7.274	-2.267	3.838e-02	0.289	-3.935	ARHGAP10	Rho GTPase activating protein 10	4	148872902	NM_024605	79658	4q31.23	Hs.368631	4	GTPase activator activity Rho GTPase activator activity protein binding intracellular cytoplasm plasma membrane cytoskeleton organization signal transduction perinuclear region of cytoplasm
230120_s_at	-0.384	4.957	-2.267	3.840e-02	0.289	-3.935	PLGLB2	plasminogen-like B2	2	-87091098, 87828720	AI088455	5342	2p11-q11	Hs.652169	12
222050_at	0.249	5.080	2.267	3.840e-02	0.289	-3.935	FXR2	fragile X mental retardation, autosomal homolog 2	17	-7435271	AI703341	9513	17p13.1	Hs.52788	19	RNA binding protein binding cytoplasm cytosolic large ribosomal subunit
204036_at	0.640	4.657	2.267	3.841e-02	0.289	-3.935	LPAR1	lysophosphatidic acid receptor 1	9	-112675874	AW269335	1902	9q31.3	Hs.126667	39	activation of MAPK activity lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of phospholipase C activity elevation of cytosolic calcium ion concentration PDZ domain binding bleb formation positive regulation of Rho protein signal transduction positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of MAPKKK cascade	Neuroactive ligand-receptor interaction Gap junction
206724_at	0.219	2.794	2.267	3.841e-02	0.289	-3.936	CBX4	chromobox homolog 4 (Pc class homolog, Drosophila)	17	-75421549	NM_003655	8535	17q25.3	Hs.714363	25	chromatin chromatin binding transcription corepressor activity nucleus chromatin assembly or disassembly anti-apoptosis negative regulation of transcription chromatin modification enzyme binding modification-dependent protein catabolic process
1553482_at	-0.174	5.135	-2.266	3.846e-02	0.290	-3.937	C15orf32	chromosome 15 open reading frame 32	15	90815910	NM_153040	145858	15q26.1	Hs.367879	4
235451_at	-0.323	7.460	-2.266	3.847e-02	0.290	-3.937	SMAD5	SMAD family member 5	5	135496434	AI439752	4090	5q31	Hs.167700	56	transcription factor activity receptor signaling protein activity protein binding intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol regulation of transcription, DNA-dependent signal transduction transforming growth factor beta receptor signaling pathway embryonic pattern specification integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	TGF-beta signaling pathway
222912_at	0.291	4.060	2.265	3.851e-02	0.290	-3.938	ARRB1	arrestin, beta 1	11	-74654129	BE207758	408	11q13	Hs.503284 Hs.625320	86	enzyme inhibitor activity protein binding intracellular membrane fraction soluble fraction cytoplasm heterotrimeric G-protein complex plasma membrane signal transduction sensory perception phototransduction regulation of G-protein coupled receptor protein signaling pathway response to stimulus	MAPK signaling pathway Chemokine signaling pathway Endocytosis
201102_s_at	0.316	5.877	2.265	3.851e-02	0.290	-3.938	PFKL	phosphofructokinase, liver	21	44544352, 44544357	NM_002626	5211	21q22.3	Hs.255093	28	nucleotide binding magnesium ion binding 6-phosphofructokinase activity 6-phosphofructokinase activity ATP binding soluble fraction cytoplasm cytosol cytosol 6-phosphofructokinase complex carbohydrate metabolic process fructose 6-phosphate metabolic process fructose 6-phosphate metabolic process glycolysis response to glucose stimulus kinase activity transferase activity kinase binding identical protein binding negative regulation of insulin secretion protein oligomerization fructose-6-phosphate binding	Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Galactose metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways
211237_s_at	0.160	6.251	2.265	3.852e-02	0.290	-3.938	FGFR4	fibroblast growth factor receptor 4	5	176446526, 176449156	AF202063	2264	5q35.1-qter	Hs.165950	90	nucleotide binding induction of an organ receptor activity fibroblast growth factor receptor activity ATP binding plasma membrane integral to plasma membrane protein amino acid phosphorylation fibroblast growth factor receptor signaling pathway transferase activity lung development	MAPK signaling pathway Endocytosis Regulation of actin cytoskeleton
1552670_a_at	-0.841	6.455	-2.265	3.852e-02	0.290	-3.938	PPP1R3B	protein phosphatase 1, regulatory (inhibitor) subunit 3B	8	-9031176	NM_024607	79660	8p23.1	Hs.458513	7	carbohydrate metabolic process glycogen metabolic process	Insulin signaling pathway
232697_at	0.247	4.273	2.265	3.852e-02	0.290	-3.938	LRFN2	leucine rich repeat and fibronectin type III domain containing 2	6	-40467350	AW161909	57497	6p21.2-p21.1	Hs.250015	5	protein binding membrane integral to membrane
212034_s_at	0.244	7.534	2.265	3.853e-02	0.290	-3.938	EXOC7	exocyst complex component 7	17	-71588693, -71588681, -71588681	AB028990	23265	17q25.1	Hs.514496	20	exocyst cytoplasm microtubule organizing center cytosol plasma membrane exocytosis protein transport centriolar satellite	Insulin signaling pathway
216909_at	0.249	5.520	2.265	3.854e-02	0.290	-3.938	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	10	-99106448	AK021460	23223	10q24.1	Hs.434251	15	protein binding nucleus nucleolus membrane integral to membrane
225570_at	0.613	8.295	2.265	3.854e-02	0.290	-3.939	SLC41A1	solute carrier family 41, member 1	1	-204024843	AW439816	254428	1q32.1	Hs.20274	4	magnesium ion binding plasma membrane cation transport cation transmembrane transporter activity integral to membrane
231002_s_at	-0.253	5.586	-2.265	3.855e-02	0.290	-3.939	RABEP1	rabaptin, RAB GTPase binding effector protein 1	17	5126281	AA778438	9135	17p13.2	Hs.584784 Hs.592121	19	GTPase activator activity protein binding cytoplasm early endosome endocytosis apoptosis membrane fusion growth factor activity protein transport recycling endosome	Endocytosis
204353_s_at	-0.231	4.070	-2.264	3.862e-02	0.290	-3.940	POT1	POT1 protection of telomeres 1 homolog (S. pombe)	7	-124249675	BC002923	25913	7q31.33	Hs.31968	40	nuclear telomere cap complex DNA binding protein binding nucleus nucleoplasm chromosome telomerase inhibitor activity telomere capping telomere capping DEAD/H-box RNA helicase binding telomere formation via telomerase negative regulation of telomere maintenance via telomerase positive regulation of telomere maintenance via telomerase DNA duplex unwinding single-stranded telomeric DNA binding positive regulation of helicase activity positive regulation of telomerase activity negative regulation of telomerase activity positive regulation of DNA strand elongation
235394_at	-0.372	6.257	-2.264	3.864e-02	0.290	-3.941	PLAA	phospholipase A2-activating protein	9	-26893368	AW614597	9373	9p21	Hs.27182	15	protein binding phospholipid metabolic process inflammatory response signal transduction phospholipase A2 activator activity
200615_s_at	0.329	7.743	2.263	3.865e-02	0.291	-3.941	AP2B1	adaptor-related protein complex 2, beta 1 subunit	17	30938394	AL567295	163	17q11.2-q12	Hs.514819	36	protein binding cytosol plasma membrane coated pit intracellular protein transport protein transporter activity vesicle-mediated transport membrane coat clathrin adaptor complex regulation of defense response to virus by virus	Endocytosis Huntington's disease
227374_at	0.226	6.107	2.263	3.867e-02	0.291	-3.941	EARS2	glutamyl-tRNA synthetase 2, mitochondrial (putative)	16	-23440834	AA833716	124454	16p12.2	Hs.620541	6	nucleotide binding RNA binding glutamate-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix glutamyl-tRNA aminoacylation ligase activity	Porphyrin and chlorophyll metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways
1555852_at	0.479	4.364	2.263	3.868e-02	0.291	-3.942	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	6	32929915, 4202792, 4007991	AI375915	5698	6p21.3	Hs.654585	72	threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex immune response peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
216452_at	0.226	3.680	2.263	3.868e-02	0.291	-3.942	TRPM3	transient receptor potential cation channel, subfamily M, member 3	9	-72588597, -72339785, -72339785	AB046836	80036	9q21.12	Hs.47288	19	calcium channel activity calcium ion binding cation transport calcium ion transport membrane integral to membrane
212917_x_at	-0.358	6.537	-2.263	3.868e-02	0.291	-3.942	RECQL	RecQ protein-like (DNA helicase Q1-like)	12	-21513111	AI814728	5965	12p12	Hs.235069	29	nucleotide binding DNA strand renaturation DNA strand annealing activity DNA binding ATP-dependent DNA helicase activity protein binding ATP binding nucleus DNA repair DNA recombination hydrolase activity
202352_s_at	-0.225	8.329	-2.263	3.868e-02	0.291	-3.942	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	17	-62767081, -62767080	AI446530	5718	17q24.2	Hs.646575	39	protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
201244_s_at	-0.367	8.859	-2.263	3.869e-02	0.291	-3.942	RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	3	-12600099	NM_002880	5894	3p25	Hs.159130	273	nucleotide binding protein serine/threonine kinase activity receptor signaling protein activity protein binding ATP binding mitochondrial outer membrane cytosol plasma membrane protein amino acid phosphorylation apoptosis cytoskeleton organization Ras protein signal transduction zinc ion binding cell proliferation transferase activity diacylglycerol binding metal ion binding nerve growth factor receptor signaling pathway	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Focal adhesion Gap junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
219579_at	0.211	5.995	2.263	3.870e-02	0.291	-3.942	RAB3IL1	RAB3A interacting protein (rabin3)-like 1	11	-61421348	NM_013401	5866	11q12-q13.1	Hs.13759	4	guanyl-nucleotide exchange factor activity protein binding
217800_s_at	-0.308	7.775	-2.263	3.870e-02	0.291	-3.942	NDFIP1	Nedd4 family interacting protein 1	5	141468507	NM_030571	80762	5q31.3	Hs.653510 Hs.9788	11	signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport
205189_s_at	0.217	6.065	2.263	3.870e-02	0.291	-3.942	FANCC	Fanconi anemia, complementation group C	9	-96901156	NM_000136	2176	9q22.3	Hs.494529	77	protein binding nucleus cytoplasm cytosol DNA repair protein complex assembly response to DNA damage stimulus
1565814_at	0.169	4.881	2.263	3.871e-02	0.291	-3.942	TRIM36	tripartite motif-containing 36	5	-114541134, -114534698, -114488357	BC017346	55521	5q22.3	Hs.519514 Hs.638953	5	acrosomal vesicle protein binding intracellular cytoplasm acrosome reaction zinc ion binding metal ion binding
224561_s_at	-0.200	11.191	-2.262	3.872e-02	0.291	-3.943	MORF4L1	mortality factor 4 like 1	15	76952226	BF340288	10933	15q24	Hs.374503	25	protein binding nucleus DNA repair response to DNA damage stimulus chromatin modification histone deacetylation Sin3 complex NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation regulation of transcription
226952_at	-0.366	5.622	-2.262	3.873e-02	0.291	-3.943	EAF1	ELL associated factor 1	3	15444067	AU149385	85403	3p25.1	Hs.716733	9	protein binding nucleus Cajal body nuclear speck regulation of transcription
203603_s_at	-0.516	5.893	-2.262	3.875e-02	0.291	-3.943	ZEB2	zinc finger E-box binding homeobox 2	2	-144862052	NM_014795	9839	2q22.3	Hs.34871	49	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent nervous system development zinc ion binding negative regulation of transcription phosphatase regulator activity sequence-specific DNA binding SMAD binding metal ion binding
229677_at	0.214	5.731	2.262	3.875e-02	0.291	-3.943	SLC39A3	solute carrier family 39 (zinc transporter), member 3	19	-2685523, -2683522	AA535975	29985	19p13.3	Hs.515046	10	zinc ion transmembrane transporter activity ion transport zinc ion transport zinc ion binding membrane integral to membrane metal ion transport metal ion transmembrane transporter activity
204564_at	0.198	5.426	2.262	3.875e-02	0.291	-3.943	PCGF3	polycomb group ring finger 3	4	689572	NM_006315	10336	4p16.3	Hs.144309 Hs.707307	5	protein binding zinc ion binding regulation of transcription metal ion binding
212282_at	-0.417	6.889	-2.262	3.876e-02	0.291	-3.943	TMEM97	transmembrane protein 97	17	23670247	BF038366	27346	17q11.2	Hs.199695	8	regulation of cell growth molecular_function cellular_component membrane integral to membrane
213428_s_at	0.478	8.445	2.262	3.876e-02	0.291	-3.944	COL6A1	collagen, type VI, alpha 1	21	46226090	AA292373	1291	21q22.3	Hs.474053	49	molecular_function protein binding extracellular region proteinaceous extracellular matrix collagen type VI cell adhesion sarcolemma	Focal adhesion ECM-receptor interaction
227964_at	0.247	5.711	2.261	3.882e-02	0.291	-3.945	FRMD8	FERM domain containing 8	11	64910616	BF435621	83786	11q13	Hs.578433	4	binding cytoskeleton
208828_at	-0.527	7.970	-2.261	3.882e-02	0.291	-3.945	POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)	9	-115209341, -115209341	BC004170	54107	9q33	Hs.108112	13	DNA-directed DNA polymerase activity protein binding intracellular nucleus DNA replication transferase activity nucleotidyltransferase activity sequence-specific DNA binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair
212503_s_at	-0.413	8.215	-2.261	3.883e-02	0.291	-3.945	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	10	-310131	N22859	22982	10p15.3	Hs.432397	7	catalytic activity nucleus transcription factor binding metabolic process
201377_at	-0.207	6.980	-2.261	3.883e-02	0.291	-3.945	UBAP2L	ubiquitin associated protein 2-like	1	152459278, 152459948	NM_014847	9898	1q21.3	Hs.490551	12	protein binding
223492_s_at	-0.328	9.417	-2.261	3.883e-02	0.291	-3.945	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2	238200962, 238265545, 238265545	BC004958	9208	2q37.3	Hs.471779	16	DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity
208851_s_at	0.270	5.591	2.261	3.884e-02	0.291	-3.945	THY1	Thy-1 cell surface antigen	11	-118793865	AL161958	7070	11q22.3-q23	Hs.644697 Hs.719101	45	angiogenesis Rho GTPase activator activity integrin binding protein binding endoplasmic reticulum cytosol plasma membrane integral to plasma membrane negative regulation of protein kinase activity cytoskeleton organization external side of plasma membrane cell-cell adhesion negative regulation of cell migration dendrite growth cone anchored to membrane anchored to external side of plasma membrane GPI anchor binding positive regulation of GTPase activity membrane raft retinal cone cell development focal adhesion formation negative regulation of axonogenesis negative regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of release of sequestered calcium ion into cytosol	Leukocyte transendothelial migration
226618_at	-0.489	7.177	-2.261	3.884e-02	0.291	-3.945	FLJ25076	probable ubiquitin-conjugating enzyme E2 FLJ25076	5	6501735	AW572911	134111	5p15.31	Hs.126856	3	nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process
205277_at	-0.321	6.129	-2.261	3.885e-02	0.291	-3.946	PRDM2	PR domain containing 2, with ZNF domain	1	13899321, 13903936, 13903936, 13948462	NM_012231	7799	1p36.21	Hs.371823	39	transcription factor activity intracellular nucleus Golgi apparatus regulation of transcription, DNA-dependent methyltransferase activity zinc ion binding transferase activity histone-lysine N-methyltransferase activity metal ion binding
1557954_at	-0.317	5.050	-2.261	3.886e-02	0.291	-3.946	CXorf15	chromosome X open reading frame 15	X	16714480	BM757251	55787	Xp22.2	Hs.555961	8
228805_at	-0.551	6.242	-2.261	3.886e-02	0.291	-3.946	C5orf25	chromosome 5 open reading frame 25	5	175597975	BF116060	375484	5q35.2	Hs.653052 Hs.715124	4
202688_at	0.663	7.513	2.261	3.886e-02	0.291	-3.946	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	3	-173706157	NM_003810	8743	3q26	Hs.478275	343	cytokine activity tumor necrosis factor receptor binding extracellular region extracellular space soluble fraction integral to plasma membrane induction of apoptosis immune response signal transduction cell-cell signaling zinc ion binding activation of pro-apoptotic gene products membrane positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity
220160_s_at	0.231	6.548	2.260	3.887e-02	0.291	-3.946	KPTN	kaptin (actin binding protein)	19	-52670211	NM_007059	11133	19q13.32	Hs.25441	11	actin binding protein binding nucleus cytoplasm microtubule organizing center cell motion actin filament organization sensory perception of sound actin cytoskeleton growth cone stereocilium cell projection perinuclear region of cytoplasm
224922_at	-0.246	5.925	-2.260	3.887e-02	0.291	-3.946	CSNK2A2	casein kinase 2, alpha prime polypeptide	16	-56749312	AI022089	1459	16q21	Hs.82201	143	nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity protein N-terminus binding regulation of cell cycle	Wnt signaling pathway Adherens junction Tight junction
204659_s_at	-0.339	6.746	-2.260	3.888e-02	0.291	-3.946	GFER	growth factor, augmenter of liver regeneration	16	1974150	AF124604	2671	16p13.3-p13.12	Hs.27184	30	protein binding cellular_component mitochondrion spermatogenesis cell proliferation oxidoreductase activity thiol oxidase activity oxidation reduction
206503_x_at	0.254	4.526	2.260	3.893e-02	0.291	-3.947	PML	promyelocytic leukemia	15	72074066, 72074066, 72074066	NM_002675	5371	15q22	Hs.526464	208	response to hypoxia DNA binding intracellular insoluble fraction nucleus nucleoplasm nucleolus cytoplasm protein complex assembly induction of apoptosis activation of caspase activity DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest cell cycle arrest transforming growth factor beta receptor signaling pathway common-partner SMAD protein phosphorylation SMAD protein nuclear translocation cell aging zinc ion binding negative regulation of cell proliferation response to UV response to gamma radiation nuclear matrix negative regulation of transcription negative regulation of angiogenesis PML body myeloid cell differentiation negative regulation of cell growth transcription regulator activity PML body organization ubiquitin protein ligase binding nuclear membrane response to cytokine stimulus DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis protein homodimerization activity interspecies interaction between organisms regulation of MHC class I biosynthetic process SMAD binding metal ion binding retinoic acid receptor signaling pathway maintenance of protein location in nucleus	Ubiquitin mediated proteolysis Pathways in cancer Acute myeloid leukemia
222696_at	-0.543	7.022	-2.259	3.896e-02	0.291	-3.948	AXIN2	axin 2	17	-60955146	BF684446	8313	17q23-q24	Hs.156527	38	somitogenesis intramembranous ossification signal transducer activity protein binding intracellular nucleus cytoplasm signal transduction multicellular organismal development negative regulation of cell proliferation regulation of Wnt receptor signaling pathway negative regulation of osteoblast differentiation	Wnt signaling pathway Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma
232042_at	0.199	4.581	2.259	3.897e-02	0.291	-3.948	TTYH2	tweety homolog 2 (Drosophila)	17	69721290, 69756099	BC005168	94015	17q25.1	Hs.27935	8	ion channel activity chloride channel activity calcium ion binding protein binding plasma membrane ion transport integral to membrane chloride ion binding chloride channel complex
226658_at	-0.367	4.837	-2.259	3.898e-02	0.291	-3.948	PDPN	podoplanin	1	13782838, 13784553	AW590196	10630	1p36.21	Hs.468675	48	cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development
230242_at	0.212	6.105	2.259	3.899e-02	0.291	-3.949	NFASC	neurofascin homolog (chicken)	1	203064404, 203064404, 203179976	AA634220	23114	1q32.1	Hs.13349	28	protein binding plasma membrane cell adhesion integral to membrane	Cell adhesion molecules (CAMs)
230114_at	0.257	4.388	2.259	3.900e-02	0.291	-3.949	HOXB8	homeobox B8	17	-44044706	AI492162	3218	17q21.3	Hs.514292	14	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development grooming behavior adult locomotory behavior anterior/posterior pattern formation sensory perception of pain dorsal spinal cord development sequence-specific DNA binding embryonic skeletal system morphogenesis
235508_at	0.211	5.918	2.259	3.901e-02	0.292	-3.949	PML	promyelocytic leukemia	15	72074066, 72074066, 72074066	AW291023	5371	15q22	Hs.526464	208	response to hypoxia DNA binding intracellular insoluble fraction nucleus nucleoplasm nucleolus cytoplasm protein complex assembly induction of apoptosis activation of caspase activity DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest cell cycle arrest transforming growth factor beta receptor signaling pathway common-partner SMAD protein phosphorylation SMAD protein nuclear translocation cell aging zinc ion binding negative regulation of cell proliferation response to UV response to gamma radiation nuclear matrix negative regulation of transcription negative regulation of angiogenesis PML body myeloid cell differentiation negative regulation of cell growth transcription regulator activity PML body organization ubiquitin protein ligase binding nuclear membrane response to cytokine stimulus DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis protein homodimerization activity interspecies interaction between organisms regulation of MHC class I biosynthetic process SMAD binding metal ion binding retinoic acid receptor signaling pathway maintenance of protein location in nucleus	Ubiquitin mediated proteolysis Pathways in cancer Acute myeloid leukemia
226647_at	0.212	5.502	2.258	3.904e-02	0.292	-3.950	TMEM25	transmembrane protein 25	11	117907012, 117907012	AL562445	84866	11q23.3	Hs.564188	9	extracellular region plasma membrane integral to membrane
226351_at	0.237	6.119	2.258	3.905e-02	0.292	-3.950	NSUN4	NOL1/NOP2/Sun domain family, member 4	1	46578976	AK021577	387338	1p34	Hs.163424	4	methyltransferase activity transferase activity
207980_s_at	-0.839	4.817	-2.258	3.905e-02	0.292	-3.950	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	6	-139735089	NM_006079	10370	6q23.3	Hs.82071	21	negative regulation of transcription from RNA polymerase II promoter nuclear chromatin response to hypoxia liver development transcription factor activity transcription coactivator activity transcription corepressor activity protein binding nucleus anti-apoptosis determination of left/right symmetry heart development heart development positive regulation of specific transcription from RNA polymerase II promoter positive regulation of cell-cell adhesion negative regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway response to fluid shear stress positive regulation of cell cycle positive regulation of transcription, DNA-dependent
241791_at	-0.394	11.361	-2.258	3.907e-02	0.292	-3.950	TTN	titin	2	-179318289, -179098963	BF825274	7273	2q31	Hs.134602	116	nucleotide binding magnesium ion binding condensed nuclear chromosome protein serine/threonine kinase activity Rho guanyl-nucleotide exchange factor activity calcium ion binding calmodulin binding ATP binding intracellular nucleus cytoplasm protein amino acid phosphorylation striated muscle contraction mitotic chromosome condensation structural constituent of muscle transferase activity Z disc muscle thin filament assembly muscle thick filament assembly telethonin binding regulation of Rho protein signal transduction identical protein binding protein self-association sarcomere organization regulation of protein kinase activity cardiac muscle fiber development regulation of catalytic activity actin filament binding alpha-actinin binding response to calcium ion cardiac myofibril assembly cardiac muscle tissue morphogenesis	Hypertrophic cardiomyopathy (HCM)
222202_at	-0.148	2.235	-2.258	3.907e-02	0.292	-3.951	LOC644213	glyceraldehyde-3-phosphate dehydrogenase pseudogene	1		AK024355	644213	1p12	Hs.647686
226568_at	0.403	5.193	2.258	3.908e-02	0.292	-3.951	FAM102B	family with sequence similarity 102, member B	1	108904493	AI478747	284611	1p13.3	Hs.200230	6
244463_at	-0.358	4.243	-2.258	3.908e-02	0.292	-3.951	ADAM23	ADAM metallopeptidase domain 23	2	207016612	AI879064	8745	2q33	Hs.591643	13	metalloendopeptidase activity integrin binding protein binding extracellular region plasma membrane integral to plasma membrane proteolysis cell adhesion central nervous system development zinc ion binding
1554045_at	0.180	3.826	2.257	3.910e-02	0.292	-3.951	ZNF24	zinc finger protein 24	18	-31166175	AF542097	7572	18q12	Hs.514802	15	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding negative regulation of transcription transcription repressor activity metal ion binding
235283_at	-0.348	4.842	-2.257	3.910e-02	0.292	-3.951	INTS6	integrator complex subunit 6	13	-50921621, -50833701	AA262171	26512	13q14.12-q14.2	Hs.439440	13	transmembrane receptor activity protein binding nucleus nucleolus cytoskeleton snRNA processing integrator complex
236605_at	0.197	5.721	2.257	3.911e-02	0.292	-3.951	EIF3K	eukaryotic translation initiation factor 3, subunit K	19	43801561	AA470798	27335	19q13.2	Hs.314359	15	translation initiation factor activity translation initiation factor activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex regulation of translational initiation ribosome binding
1555752_at	-0.210	5.962	-2.257	3.911e-02	0.292	-3.952	STH	saitohin	17	41432452	AY179170	246744	17q21.1	Hs.661831	19	nucleus cytoplasm
242441_at	-0.324	5.294	-2.257	3.912e-02	0.292	-3.952	LOC646548	similar to ADAM metallopeptidase domain 21 preproprotein	14		AA608973	646548	14q24.2
222393_s_at	-0.530	7.700	-2.257	3.912e-02	0.292	-3.952	NAT13	N-acetyltransferase 13 (GCN5-related)	3	-114920530	AU149868	80218	3q13.2	Hs.596074	5	protein binding cytoplasm N-terminal protein amino acid acetylation N-acetyltransferase activity metabolic process acyltransferase activity transferase activity
218322_s_at	0.301	5.159	2.257	3.913e-02	0.292	-3.952	ACSL5	acyl-CoA synthetase long-chain family member 5	10	114123905, 114125012, 114125945	NM_016234	51703	10q25.1-q25.2	Hs.11638	21	nucleotide binding magnesium ion binding long-chain-fatty-acid-CoA ligase activity ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity	Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway
236721_at	-0.296	3.935	-2.257	3.916e-02	0.292	-3.953	ALKBH1	alkB, alkylation repair homolog 1 (E. coli)	14	-77208501	AI922200	8846	14q24.3	Hs.94542	6	DNA dealkylation
233204_at	-0.304	4.249	-2.256	3.917e-02	0.292	-3.953	LOC728153	similar to FAM133B protein	5		AA115105	728153	5q12.1	Hs.18564 Hs.664739	1
203039_s_at	0.308	10.240	2.256	3.918e-02	0.292	-3.953	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	2	-206696047	NM_005006	4719	2q33-q34	Hs.471207	16	NADH dehydrogenase activity iron ion binding protein binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial respiratory chain complex I mitochondrial intermembrane space mitochondrial electron transport, NADH to ubiquinone oxygen and reactive oxygen species metabolic process transport apoptosis NADH dehydrogenase (ubiquinone) activity NADH dehydrogenase (ubiquinone) activity electron carrier activity membrane electron transport chain ATP synthesis coupled electron transport cellular respiration ATP metabolic process metal ion binding 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding regulation of mitochondrial membrane potential respiratory chain	Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease
201370_s_at	-0.478	7.643	-2.256	3.918e-02	0.292	-3.953	CUL3	cullin 3	2	-225043112	AU145232	8452	2q36.2	Hs.372286	39	G1/S transition of mitotic cell cycle protein binding nucleus Golgi apparatus ubiquitin-dependent protein catabolic process cell cycle arrest cyclin catabolic process positive regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
202954_at	0.209	4.464	2.256	3.918e-02	0.292	-3.953	UBE2C	ubiquitin-conjugating enzyme E2C	20	43874661, 43875078	NM_007019	11065	20q13.12	Hs.93002	33	nucleotide binding ubiquitin-protein ligase activity ATP binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process cell cycle spindle organization mitosis cyclin catabolic process protein ubiquitination ligase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of exit from mitosis phosphoinositide-mediated signaling regulation of protein metabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Ubiquitin mediated proteolysis
210931_at	-0.535	4.674	-2.256	3.918e-02	0.292	-3.953	RNF6	ring finger protein (C3H2C3 type) 6	13	-25684904, -25684904, -25684904	AF293342	6049	13q12.2	Hs.136885	7	protein binding cellular_component biological_process zinc ion binding metal ion binding
231864_at	-0.274	6.627	-2.256	3.922e-02	0.292	-3.954	ZNF33A	zinc finger protein 33A	10	38339583	D31763	7581	10p11.2	Hs.435774	8	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221238_at	-0.248	3.776	-2.256	3.923e-02	0.292	-3.954	NSBP1	nucleosomal binding protein 1	X	-80255855	NM_030763	79366	Xq13.3	Hs.282204	7	chromatin DNA binding chromatin binding nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase I promoter transcription activator activity
212654_at	-0.162	12.787	-2.256	3.923e-02	0.292	-3.954	TPM2	tropomyosin 2 (beta)	9	-35672922, -35671989, -35671989	AL566786	7169	9p13.2-p13.1	Hs.300772	39	actin binding cytoplasm cytoskeleton muscle thin filament tropomyosin structural constituent of muscle regulation of ATPase activity	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
1554018_at	0.340	2.390	2.256	3.924e-02	0.292	-3.954	GPNMB	glycoprotein (transmembrane) nmb	7	23252840	BC011595	10457	7p15	Hs.190495	24	osteoblast differentiation integrin binding integral to plasma membrane cell adhesion heparin binding negative regulation of cell proliferation membrane cytoplasmic membrane-bounded vesicle bone mineralization melanosome
220961_s_at	0.287	5.737	2.256	3.924e-02	0.292	-3.954	TBRG4	transforming growth factor beta regulator 4	7	-45106223	NM_030900	9238	7p14-p13	Hs.231411	13	G1 phase of mitotic cell cycle protein kinase activity protein binding ATP binding mitochondrion apoptosis cell cycle arrest positive regulation of cell proliferation
225947_at	0.312	6.420	2.255	3.926e-02	0.292	-3.955	MYO19	myosin XIX	17	-31943030, -31925712, -31925711	AA994178	80179	17q12	Hs.302051	3	nucleotide binding motor activity actin binding ATP binding cytoplasm myosin complex
209763_at	0.537	7.134	2.255	3.927e-02	0.292	-3.955	CHRDL1	chordin-like 1	X	-109803740, -109803740	AL049176	91851	Xq23	Hs.496587	10	ossification extracellular region extracellular region multicellular organismal development nervous system development cell differentiation BMP signaling pathway
210452_x_at	0.245	4.717	2.255	3.929e-02	0.292	-3.955	CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	19	-15849833	D26480	8529	19pter-p13.11	Hs.558423	35	monooxygenase activity protein binding endoplasmic reticulum microsome leukotriene metabolic process electron carrier activity membrane heme binding metal ion binding leukotriene-B4 20-monooxygenase activity oxidation reduction	Arachidonic acid metabolism Metabolic pathways
219141_s_at	0.146	6.701	2.255	3.929e-02	0.292	-3.956	AMBRA1	autophagy/beclin-1 regulator 1	11	-46374539	NM_017749	55626	11p11.2	Hs.654644	7	cytoplasm autophagic vacuole autophagy multicellular organismal development nervous system development cell differentiation cytoplasmic vesicle
203848_at	-0.285	6.645	-2.254	3.932e-02	0.292	-3.956	AKAP8	A kinase (PRKA) anchor protein 8	19	-15325334	AL050160	10270	19p13.1	Hs.719292	18	condensed chromosome female pronucleus DNA binding intracellular nucleus nucleolus mitosis mitotic chromosome condensation signal transduction zinc ion binding nuclear matrix protein kinase binding metal ion binding
214553_s_at	-0.375	9.327	-2.254	3.932e-02	0.292	-3.956	ARPP19	cAMP-regulated phosphoprotein, 19kDa	15	-50626723	NM_006628	10776	15q21.2	Hs.512908	10	receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import
200636_s_at	0.395	5.555	2.254	3.933e-02	0.292	-3.956	PTPRF	protein tyrosine phosphatase, receptor type, F	1	43769133	NM_002840	5792	1p34	Hs.272062	49	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation cell adhesion transmembrane receptor protein tyrosine phosphatase signaling pathway membrane hydrolase activity	Cell adhesion molecules (CAMs) Adherens junction Insulin signaling pathway
232217_at	0.248	4.927	2.254	3.934e-02	0.292	-3.957	FAM26E	family with sequence similarity 26, member E	6	116939500	AI292175	254228	6q22.1	Hs.660142	4	membrane integral to membrane
201937_s_at	-0.284	7.390	-2.254	3.935e-02	0.293	-3.957	DNPEP	aspartyl aminopeptidase	2	-219946423	NM_012100	23549	2q35	Hs.258551	8	aminopeptidase activity protein binding cytoplasm vacuole proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding metal ion binding
223458_at	0.238	5.198	2.254	3.937e-02	0.293	-3.957	SEZ6L2	seizure related 6 homolog (mouse)-like 2	16	-29789980	BC000567	26470	16p11.2	Hs.6314	10	endoplasmic reticulum plasma membrane integral to membrane
231115_at	-0.181	3.549	-2.254	3.937e-02	0.293	-3.957	POLH	polymerase (DNA directed), eta	6	43651855	AI890529	5429	6p21.1	Hs.655467	65	magnesium ion binding DNA synthesis during DNA repair damaged DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm nucleolus cytoplasm regulation of DNA repair pyrimidine dimer repair postreplication repair response to DNA damage stimulus response to UV-C transferase activity nucleotidyltransferase activity
234923_at	-0.356	5.268	-2.253	3.941e-02	0.293	-3.958	GARNL1	GTPase activating Rap/RanGAP domain-like 1	14	-35077308	AK022988	253959	14q13.2	Hs.113150	10	GTPase activator activity intracellular nucleus cytoplasm mitochondrion regulation of small GTPase mediated signal transduction
229313_at	-0.327	9.661	-2.253	3.942e-02	0.293	-3.958	ANO5	anoctamin 5	11	22171297	AA843962	203859	11p14.3	Hs.154329	6	ion channel activity chloride channel activity calcium ion binding endoplasmic reticulum ion transport membrane integral to membrane chloride ion binding chloride channel complex
206373_at	0.473	6.810	2.253	3.945e-02	0.293	-3.959	ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	3	148609870	NM_003412	7545	3q24	Hs.598590 Hs.647962	17	transcription factor activity protein binding intracellular nucleus cytoplasm pattern specification process brain development behavior zinc ion binding regulation of smoothened signaling pathway cell differentiation inner ear morphogenesis metal ion binding
207250_at	-0.179	3.737	-2.253	3.945e-02	0.293	-3.959	SIX6	SIX homeobox 6	14	60045690	NM_007374	4990	14q22.3-q23	Hs.194756	10	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development visual perception organ morphogenesis sequence-specific DNA binding
230957_at	0.208	4.080	2.253	3.947e-02	0.293	-3.959	PCDHB19P	protocadherin beta 19 pseudogene	5	140599872	BE463846	84054	5q31	Hs.570898	4
201267_s_at	-0.268	9.617	-2.252	3.949e-02	0.293	-3.960	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11	-47396895	AL545523	5702	11p12-p13	Hs.250758	57	nucleotide binding proteasome complex blastocyst development transcription coactivator activity transcription corepressor activity protein binding ATP binding nucleus cytoplasm cytosol hydrolase activity nucleoside-triphosphatase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
238799_at	-0.238	3.277	-2.252	3.952e-02	0.293	-3.961	ATP5S	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)	14	49848796, 49848796	BE968806	27109	14q21.3	Hs.438489	12	mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o)
224822_at	0.241	6.747	2.252	3.953e-02	0.293	-3.961	DLC1	deleted in liver cancer 1	8	-13116452, -12985242, -12985242	AA524250	10395	8p22	Hs.134296	48	neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation
1556133_s_at	-0.176	2.976	-2.252	3.953e-02	0.293	-3.961	LOC100169752	hypothetical LOC100169752	10	127252929	BI559430	100169752	10q	Hs.652647	1
237373_at	0.159	3.485	2.252	3.954e-02	0.293	-3.961	RAB20	RAB20, member RAS oncogene family	13	-109973413	BE464359	55647	13q34	Hs.719403	7	nucleotide binding GTP binding Golgi apparatus small GTPase mediated signal transduction protein transport
220507_s_at	0.220	5.284	2.251	3.956e-02	0.293	-3.961	UPB1	ureidopropionase, beta	22	23221250	NM_016327	51733	22q11.2	Hs.474388	10	beta-ureidopropionase activity beta-ureidopropionase activity cytoplasm cytosol nitrogen compound metabolic process zinc ion binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds metal ion binding	Pyrimidine metabolism beta-Alanine metabolism Pantothenate and CoA biosynthesis Drug metabolism - other enzymes Metabolic pathways
203960_s_at	0.282	5.652	2.251	3.956e-02	0.293	-3.962	HSPB11	heat shock protein family B (small), member 11	1	-54159821	NM_016126	51668	1p32.1-p33	Hs.525462 Hs.624686	9	response to stress cell adhesion
203267_s_at	-0.220	6.407	-2.251	3.957e-02	0.293	-3.962	DRG2	developmentally regulated GTP binding protein 2	17	17932007	BF223206	1819	17p11.2	Hs.78582	12	nucleotide binding GTP binding intracellular cytoplasm signal transduction
212620_at	0.225	6.409	2.251	3.958e-02	0.293	-3.962	ZNF609	zinc finger protein 609	15	62578671	AW165979	23060	15q22.31	Hs.595451 Hs.696256 Hs.719276	7	intracellular nucleus zinc ion binding metal ion binding
227577_at	-0.430	6.640	-2.250	3.963e-02	0.294	-3.963	EXOC8	exocyst complex component 8	1	-229535104	AI168350	149371	1q42.2	Hs.356198	11	protein binding cytoplasm exocytosis protein transport growth cone cell projection
1569722_s_at	0.161	3.782	2.250	3.963e-02	0.294	-3.963	LOC219731	hypothetical protein LOC219731	10		BC032757	219731	10p14	Hs.585473	1
220901_at	-0.408	5.578	-2.250	3.963e-02	0.294	-3.963	GPR157	G protein-coupled receptor 157	1	-9087062	NM_024980	80045	1p36.23	Hs.632367	5	G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane
229651_at	0.272	4.761	2.250	3.963e-02	0.294	-3.963	SEZ6	seizure related 6 homolog (mouse)	17	-24306072	H05303	124925	17q11.2	Hs.21837	8	plasma membrane integral to membrane
217465_at	-0.322	3.667	-2.250	3.964e-02	0.294	-3.963	NCKAP1	NCK-associated protein 1	2	-183497849	AK001291	10787	2q32	Hs.603732	20	protein binding plasma membrane apoptosis central nervous system development integral to membrane cell projection	Regulation of actin cytoskeleton
225433_at	-0.398	6.980	-2.250	3.965e-02	0.294	-3.964	GTF2A1	general transcription factor IIA, 1, 19/37kDa	14	-80716146, -80716146	AU144104	2957	14q31.1	Hs.592334 Hs.593630	45	DNA binding transcription coactivator activity nucleus nucleoplasm transcription factor TFIIA complex nucleolus cytoplasm transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter transcription factor binding general RNA polymerase II transcription factor activity TATA-binding protein binding general transcription from RNA polymerase II promoter regulation of transcription protein heterodimerization activity	Basal transcription factors
1562739_at	-0.253	4.150	-2.250	3.965e-02	0.294	-3.964	LOC285593	hypothetical LOC285593	5	172939251, 172939262	BC033564	285593	5q35.2	Hs.409730	1
224560_at	0.429	6.979	2.250	3.965e-02	0.294	-3.964	TIMP2	TIMP metallopeptidase inhibitor 2	17	-74360653	BF107565	7077	17q25	Hs.633514	168	enzyme inhibitor activity integrin binding protein binding extracellular region basement membrane enzyme activator activity metalloendopeptidase inhibitor activity negative regulation of cell proliferation cell surface regulation of cAMP metabolic process regulation of MAPKKK cascade regulation of neuron differentiation
234711_s_at	0.163	5.040	2.250	3.968e-02	0.294	-3.964	BCORL1	BCL6 co-repressor-like 1	X	128944349	AL136450	63035	Xq25-q26.1	Hs.496748 Hs.504534	4	nucleus chromatin modification regulation of transcription
235682_s_at	0.221	4.998	2.250	3.968e-02	0.294	-3.964	HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	1	-16213109	BF306676	27129	1p36.23-p34.3	Hs.502612	7	response to unfolded protein regulation of heart contraction protein C-terminus binding response to heat
215343_at	0.196	2.435	2.250	3.970e-02	0.294	-3.965	CCDC88C	coiled-coil domain containing 88C	14	-90807419	AF070587	440193	14q32.11	Hs.525536	7	regulation of protein amino acid phosphorylation insoluble fraction Wnt receptor signaling pathway PDZ domain binding protein destabilization protein self-association protein homooligomerization
238084_at	0.171	4.652	2.249	3.970e-02	0.294	-3.965	PCGF3	polycomb group ring finger 3	4	689572	AA187595	10336	4p16.3	Hs.144309 Hs.707307	5	protein binding zinc ion binding regulation of transcription metal ion binding
1568598_at	0.308	5.170	2.249	3.970e-02	0.294	-3.965	KAZALD1	Kazal-type serine peptidase inhibitor domain 1	10	102810988	BF434771	81621	10q24.31	Hs.534859 Hs.632079	11	ossification regulation of cell growth insulin-like growth factor binding extracellular region interstitial matrix multicellular organismal development cell differentiation extracellular matrix organization
214055_x_at	-0.220	7.597	-2.249	3.971e-02	0.294	-3.965	BAT2D1	BAT2 domain containing 1	1	169721289	AW238632	23215	1q23.3	Hs.494614	5
205559_s_at	0.494	5.559	2.249	3.971e-02	0.294	-3.965	PCSK5	proprotein convertase subtilisin/kexin type 5	9	77695379	NM_006200	5125	9q21.3	Hs.368542	40	kidney development kidney development renin secretion into blood stream serine-type endopeptidase activity extracellular region extracellular space Golgi apparatus Golgi lumen signal peptide processing proteolysis cell-cell signaling heart development embryo implantation peptidase activity anterior/posterior pattern formation viral assembly, maturation, egress, and release secretory granule respiratory tube development nerve growth factor processing limb morphogenesis cytokine biosynthetic process peptide binding peptide biosynthetic process embryonic gut development embryonic skeletal system development
226356_at	0.234	6.498	2.249	3.974e-02	0.294	-3.966	FAM73B	family with sequence similarity 73, member B	9	130839073	AA535864	84895	9q34.11	Hs.632693	3	membrane integral to membrane
201317_s_at	-0.181	10.083	-2.249	3.976e-02	0.294	-3.966	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	7	-42922986	NM_002787	5683	7p13	Hs.333786	48	threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process	Proteasome
227388_at	-0.373	7.954	-2.249	3.977e-02	0.294	-3.966	TUSC1	tumor suppressor candidate 1	9	-25666386	AA479016	286319	9p21.2	Hs.26268 Hs.606014	2
221607_x_at	0.432	10.669	2.248	3.978e-02	0.294	-3.967	ACTG1	actin, gamma 1	17	-77091593	BC001920	71	17q25	Hs.514581	102	nucleotide binding structural constituent of cytoskeleton ATP binding cytoplasm cytoskeleton cell motion identical protein binding response to calcium ion	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
225102_at	0.275	8.181	2.248	3.979e-02	0.294	-3.967	MGLL	monoglyceride lipase	3	-128890598, -128890598	BG168471	11343	3q21.3	Hs.277035	15	lysophospholipase activity lipid metabolic process inflammatory response hydrolase activity acylglycerol lipase activity	Glycerolipid metabolism Metabolic pathways
205977_s_at	0.234	4.696	2.248	3.980e-02	0.294	-3.967	EPHA1	EPH receptor A1	7	-142798327	NM_005232	2041	7q34	Hs.89839	30	nucleotide binding receptor activity ephrin receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity	Axon guidance
218294_s_at	-0.275	5.977	-2.248	3.981e-02	0.294	-3.967	NUP50	nucleoporin 50kDa	22	43938389, 43939215	AF267865	10762	22q13.31	Hs.715672	15	protein binding nucleus nuclear pore nucleoplasm protein transport membrane intracellular transport mRNA transport intracellular protein transmembrane transport
219566_at	-0.326	7.622	-2.248	3.983e-02	0.294	-3.968	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	19	34848166	NM_024310	79156	19q12	Hs.466383	5	nucleus cytoplasm lysosome apoptosis induction of apoptosis zinc ion binding metal ion binding perinuclear region of cytoplasm
203437_at	-0.369	9.163	-2.248	3.984e-02	0.294	-3.968	TMEM11	transmembrane protein 11	17	-21041854	NM_003876	8834	17p11.2	Hs.719186	4	molecular_function protein binding integral to plasma membrane biological_process membrane
221417_x_at	0.189	3.960	2.248	3.984e-02	0.294	-3.968	S1PR5	sphingosine-1-phosphate receptor 5	19	-10484622	NM_030760	53637	19p13.2	Hs.501561	16	lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane	Neuroactive ligand-receptor interaction
211981_at	0.355	6.614	2.248	3.984e-02	0.294	-3.968	COL4A1	collagen, type IV, alpha 1	13	-109599310	NM_001845	1282	13q34	Hs.17441	83	extracellular matrix structural constituent binding extracellular region collagen collagen type IV	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
235473_at	0.248	3.041	2.247	3.985e-02	0.294	-3.968	MED6	mediator complex subunit 6	14	-70120709	BF434383	10001	14q24.2	Hs.497353	22	RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter
63305_at	0.234	6.646	2.247	3.988e-02	0.294	-3.969	PKNOX2	PBX/knotted 1 homeobox 2	11	124539768	D81792	63876		Hs.719275	7	transcription factor activity actin monomer binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter actin cytoskeleton microtubule cytoskeleton sequence-specific DNA binding actin filament binding
223423_at	0.362	4.717	2.247	3.988e-02	0.294	-3.969	GPR160	G protein-coupled receptor 160	3	171238428	BC000181	26996	3q26.2-q27	Hs.231320	4	receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
224619_at	-0.303	8.558	-2.247	3.990e-02	0.294	-3.969	CASC4	cancer susceptibility candidate 4	15	42368220	BE904551	113201	15q15.3	Hs.512867	6	membrane integral to membrane
1555068_at	-0.214	2.704	-2.247	3.990e-02	0.294	-3.969	WNK1	WNK lysine deficient protein kinase 1	12	732485	BC021121	65125	12p13.3	Hs.709894	51	nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process
235911_at	0.240	5.235	2.247	3.992e-02	0.294	-3.969	LOC440995	hypothetical protein LOC440995	3		AI885815	440995	3q29	Hs.662242	1
52940_at	-0.386	6.265	-2.247	3.992e-02	0.294	-3.970	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	11	-395715, -395715	AA085764	59307	11p15.5	Hs.501624	13	negative regulation of cytokine-mediated signaling pathway transmembrane receptor activity protein binding acute-phase response signal transduction membrane integral to membrane negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation of transcription factor activity negative regulation of chemokine biosynthetic process innate immune response
212640_at	0.376	5.977	2.246	3.997e-02	0.295	-3.971	PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	3	-124696052	AV712602	201562	3q21.1	Hs.705480	5	protein binding endoplasmic reticulum membrane integral to membrane	Biosynthesis of unsaturated fatty acids
205337_at	0.212	2.805	2.246	4.000e-02	0.295	-3.971	DCT	dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)	13	-93889841	AL139318	1638	13q32	Hs.301865	41	dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development	Tyrosine metabolism Metabolic pathways Melanogenesis
230702_at	0.214	5.194	2.245	4.001e-02	0.295	-3.971	C8orf16	chromosome 8 open reading frame 16	8		BE674736	83735	8p23.1	Hs.660259	1
218621_at	0.221	3.958	2.245	4.001e-02	0.295	-3.971	HEMK1	HemK methyltransferase family member 1	3	50581912	NM_016173	51409	3p21.3	Hs.517987 Hs.599362	4	DNA binding DNA methylation protein amino acid methylation N-methyltransferase activity protein methyltransferase activity transferase activity methylation	Androgen and estrogen metabolism Histidine metabolism Tyrosine metabolism Aminophosphonate metabolism Selenoamino acid metabolism
1557783_at	0.196	4.767	2.245	4.003e-02	0.295	-3.972	LOC100133991	similar to hCG1995169	17	40681085, 40695340	BC031942	100133991	17q21.31	Hs.668927	2
220539_at	-0.386	6.761	-2.245	4.004e-02	0.295	-3.972	C10orf92	chromosome 10 open reading frame 92	10	-134471886	NM_017609	54777	10q26.3	Hs.298038	6
231859_at	-0.243	4.943	-2.244	4.009e-02	0.295	-3.973	C14orf132	chromosome 14 open reading frame 132	14	95575414	AK025915	56967	14q32.2	Hs.6434	6	membrane integral to membrane
1569368_at	0.231	4.748	2.244	4.010e-02	0.295	-3.973	LOC283693	actin, gamma pseudogene	15		BC014481	283693	15q25.2	Hs.560399	1
212122_at	-0.295	7.852	-2.244	4.012e-02	0.295	-3.974	RHOQ	ras homolog gene family, member Q	2	46623370	AW771590	23433	2p21	Hs.709193	27	nucleotide binding GTPase activity profilin binding GTP binding intracellular cytoplasm actin filament plasma membrane GTP catabolic process small GTPase mediated signal transduction insulin receptor signaling pathway regulation of cell shape positive regulation of specific transcription from RNA polymerase II promoter cortical actin cytoskeleton organization GBD domain binding regulation of actin cytoskeleton organization membrane raft positive regulation of glucose import positive regulation of filopodium assembly regulation of establishment of protein localization	Insulin signaling pathway
206698_at	-0.534	6.422	-2.244	4.013e-02	0.295	-3.974	XK	X-linked Kx blood group (McLeod syndrome)	X	37430051	NM_021083	7504	Xp21.1	Hs.78919	24	transporter activity protein binding transport amino acid transport membrane integral to membrane
236753_at	0.231	5.390	2.244	4.014e-02	0.295	-3.974	tcag7.1307	hypothetical LOC154822	7	158493805	BE297424	154822	7q36.3	Hs.667767 Hs.718785	2
220204_s_at	0.171	3.693	2.244	4.014e-02	0.295	-3.974	BMP8A	bone morphogenetic protein 8a	1	39729904	NM_024732	353500	1p34.3	Hs.472497	3	ossification cytokine activity extracellular region extracellular space multicellular organismal development growth factor activity cell differentiation growth cartilage development	Hedgehog signaling pathway TGF-beta signaling pathway
226730_s_at	-0.217	5.258	-2.244	4.015e-02	0.295	-3.975	USP37	ubiquitin specific peptidase 37	2	-219023217	BF789968	57695	2q35	Hs.166068	13	ubiquitin thiolesterase activity nucleus ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
212988_x_at	0.424	10.748	2.244	4.016e-02	0.295	-3.975	ACTG1	actin, gamma 1	17	-77091593	AL515810	71	17q25	Hs.514581	102	nucleotide binding structural constituent of cytoskeleton ATP binding cytoplasm cytoskeleton cell motion identical protein binding response to calcium ion	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
201803_at	-0.206	9.216	-2.243	4.016e-02	0.295	-3.975	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	4	57539865	NM_000938	5431	4q12	Hs.602757	92	magnesium ion binding nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm DNA-directed RNA polymerase II, core complex transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
220065_at	0.821	3.920	2.243	4.016e-02	0.295	-3.975	TNMD	tenomodulin	X	99726445	NM_022144	64102	Xq21.33-q23	Hs.132957	13	membrane integral to membrane
201228_s_at	-0.334	6.145	-2.243	4.016e-02	0.295	-3.975	ARIH2	ariadne homolog 2 (Drosophila)	3	48931284	AW074830	10425	3p21.2-p21.3	Hs.633601	14	nucleic acid binding protein binding nucleus ubiquitin-dependent protein catabolic process multicellular organismal development zinc ion binding metal ion binding
208621_s_at	0.567	4.351	2.243	4.018e-02	0.295	-3.975	EZR	ezrin	6	-159106760, -159106760	BF663141	7430	6q25.2-q26	Hs.487027	158	ruffle cytoplasm cytosol actin filament plasma membrane microvillus cell cortex cytoskeletal anchoring at plasma membrane leukocyte adhesion cytoskeletal protein binding regulation of cell shape extrinsic to membrane membrane to membrane docking filopodium cortical cytoskeleton apical part of cell cell adhesion molecule binding actin filament binding actin filament bundle formation	Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC
204841_s_at	-0.318	4.277	-2.243	4.019e-02	0.295	-3.975	EEA1	early endosome antigen 1	12	-91690415	NM_003566	8411	12q22	Hs.567367	32	calmodulin binding phosphatidylinositol binding intracellular membrane fraction cytoplasm early endosome cytosol serine-pyruvate aminotransferase complex vesicle fusion zinc ion binding membrane synaptic vesicle to endosome fusion extrinsic to plasma membrane GTP-dependent protein binding protein homodimerization activity early endosome to late endosome transport metal ion binding	Endocytosis
241619_at	-0.369	5.260	-2.243	4.021e-02	0.295	-3.976	CALM1	calmodulin 1 (phosphorylase kinase, delta)	14	89933125	BF526558	801	14q24-q31	Hs.282410 Hs.708270	181		Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma
225026_at	-0.288	4.401	-2.243	4.021e-02	0.295	-3.976	CHD6	chromodomain helicase DNA binding protein 6	20	-39464583	BF572029	84181	20q12	Hs.371979	12	nucleotide binding chromatin DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly chromatin remodeling regulation of transcription, DNA-dependent nervous system development ATP-dependent helicase activity hydrolase activity
202010_s_at	-0.214	6.534	-2.243	4.022e-02	0.295	-3.976	ZNF410	zinc finger protein 410	14	73423338	NM_021188	57862	14q24.3	Hs.270869	9	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
227071_at	0.179	4.946	2.243	4.022e-02	0.295	-3.976	ZNF414	zinc finger protein 414	19	-8482216, -8481462	AI762558	84330	19p13.2	Hs.515114	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
226313_at	0.229	4.719	2.242	4.025e-02	0.296	-3.977	C10orf35	chromosome 10 open reading frame 35	10	71060008	H49529	219738	10q22.1	Hs.522992	5	protein binding membrane integral to membrane
224698_at	-0.286	8.873	-2.242	4.026e-02	0.296	-3.977	ESYT2	extended synaptotagmin-like protein 2	7	-158216449	AB033054	57488	7q36.3	Hs.490795	10	plasma membrane integral to membrane
1555963_x_at	0.165	4.262	2.242	4.026e-02	0.296	-3.977	B3GNT7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7	2	231968578	CA503291	93010	2q37.1	Hs.299329	4	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups	Keratan sulfate biosynthesis Metabolic pathways
201232_s_at	-0.320	8.368	-2.242	4.027e-02	0.296	-3.977	PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	11	226807	NM_002817	5719	11p15.5	Hs.134688	41	proteasome complex protein binding cytosol proteasome regulatory particle meiosis I anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
234539_at	0.163	5.005	2.242	4.027e-02	0.296	-3.977	ADARB1	adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)	21	45318920	AK027227	104	21q22.3	Hs.474018	35	double-stranded RNA binding adenosine deaminase activity intracellular mRNA processing zinc ion binding hydrolase activity metal ion binding
218232_at	0.418	5.175	2.242	4.029e-02	0.296	-3.978	C1QA	complement component 1, q subcomponent, A chain	1	22835704	NM_015991	712	1p36.12	Hs.632379	65	extracellular region extracellular region complement component C1 complex cytoplasm Golgi apparatus complement activation, classical pathway cell-cell signaling innate immune response	Complement and coagulation cascades Prion diseases Systemic lupus erythematosus
217556_at	-0.424	4.514	-2.242	4.029e-02	0.296	-3.978	CLCN4	chloride channel 4	X	10084984	W26966	1183	Xp22.3	Hs.495674	17	nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding
205356_at	-0.295	10.338	-2.242	4.029e-02	0.296	-3.978	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	3	180853626	NM_003940	8975	3q26.2-q26.3	Hs.175322	11	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding
226827_at	0.178	3.631	2.242	4.030e-02	0.296	-3.978	TMEM165	transmembrane protein 165	4	55956846	AW665624	55858	4q12	Hs.479766	6	membrane integral to membrane
240375_at	0.239	4.874	2.242	4.030e-02	0.296	-3.978	PIGV	phosphatidylinositol glycan anchor biosynthesis, class V	1	26987072	AI798773	55650	1p36.11	Hs.259605	9	mannosyltransferase activity mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
203434_s_at	0.335	6.682	2.242	4.030e-02	0.296	-3.978	MME	membrane metallo-endopeptidase	3	156280129, 156280398, 156280646, 156280772	AI433463	4311	3q25.1-q25.2	Hs.307734	128	metalloendopeptidase activity protein binding plasma membrane integral to plasma membrane proteolysis cell-cell signaling peptidase activity zinc ion binding metal ion binding	Renin-angiotensin system Hematopoietic cell lineage Alzheimer's disease
239726_at	-0.526	7.036	-2.242	4.031e-02	0.296	-3.978	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10	-61458164, -61458164	AI743588	288	10q21	Hs.499725	30	protein binding cytoplasm cytoskeleton signal transduction basolateral plasma membrane establishment of protein localization
200637_s_at	0.184	3.668	2.242	4.031e-02	0.296	-3.978	PTPRF	protein tyrosine phosphatase, receptor type, F	1	43769133	AI762627	5792	1p34	Hs.272062	49	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation cell adhesion transmembrane receptor protein tyrosine phosphatase signaling pathway membrane hydrolase activity	Cell adhesion molecules (CAMs) Adherens junction Insulin signaling pathway
215314_at	-0.431	6.912	-2.241	4.032e-02	0.296	-3.978	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10	-61458164, -61458164	AU146646	288	10q21	Hs.499725	30	protein binding cytoplasm cytoskeleton signal transduction basolateral plasma membrane establishment of protein localization
228383_at	-0.293	5.970	-2.241	4.032e-02	0.296	-3.978	PNPLA7	patatin-like phospholipase domain containing 7	9	-139474225	AK024443	375775	9q34.3	Hs.294147	6	nucleus mitochondrion lysosome endoplasmic reticulum microsome lipid metabolic process metabolic process membrane integral to membrane hydrolase activity
1569077_x_at	0.232	6.206	2.241	4.033e-02	0.296	-3.979	ZNF836	zinc finger protein 836	19	-57349936	BE791720	162962	19q13.41	Hs.631584	1	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
209559_at	0.251	6.732	2.241	4.034e-02	0.296	-3.979	HIP1R	huntingtin interacting protein 1 related	12	121885991	AB013384	9026	12q24	Hs.524815 Hs.714965	19	actin binding protein binding cytoplasm coated pit receptor-mediated endocytosis biological_process membrane clathrin coated vesicle membrane cytoplasmic vesicle phosphoinositide binding perinuclear region of cytoplasm
238367_s_at	0.216	4.475	2.241	4.035e-02	0.296	-3.979	C1orf228	chromosome 1 open reading frame 228	1	44912980	AW015512	339541	1p34.1	Hs.173679	1	binding
223341_s_at	-0.617	7.115	-2.241	4.035e-02	0.296	-3.979	SCOC	short coiled-coil protein	4	141397889, 141484046, 141484064, 141514113	AF330205	60592	4q31.1	Hs.480815	5	nucleus Golgi apparatus
227464_at	0.206	5.127	2.240	4.040e-02	0.296	-3.980	ACSF3	acyl-CoA synthetase family member 3	16	87687754, 87687754, 87687754	AW025904	197322	16q24.3	Hs.461727	6	nucleotide binding ATP binding mitochondrion lipid metabolic process fatty acid metabolic process metabolic process ligase activity acid-thiol ligase activity
1553478_at	0.203	4.033	2.240	4.043e-02	0.296	-3.981	PRR10	proline rich 10	11		NM_173579	283165	11q24.2	Hs.376015	3
201871_s_at	-0.367	8.718	-2.240	4.043e-02	0.296	-3.981	UBXN1	UBX domain protein 1	11	-62200547	NM_015853	51035	11q12.3	Hs.351296	9	proteasome complex cytoplasm polyubiquitin binding proteasomal ubiquitin-dependent protein catabolic process ATPase binding
1552323_s_at	0.452	3.828	2.240	4.044e-02	0.296	-3.981	FAM122C	family with sequence similarity 122C	X	133768889	NM_138819	159091	Xq26.3	Hs.269127	3
1552924_a_at	-0.179	4.051	-2.240	4.046e-02	0.296	-3.981	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	12	-122033979	AL133612	57605	12q24.31	Hs.272759	6	calcium ion binding intracellular transport metabolic process lipid binding membrane integral to membrane intracellular membrane-bounded organelle
215389_s_at	0.328	6.013	2.240	4.046e-02	0.296	-3.981	TNNT2	troponin T type 2 (cardiac)	1	-199594764	X79857	7139	1q32	Hs.533613	116	actin binding tropomyosin binding troponin complex regulation of heart contraction muscle filament sliding troponin C binding troponin I binding negative regulation of ATPase activity positive regulation of ATPase activity response to calcium ion ventricular cardiac muscle morphogenesis	Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM)
1553279_at	0.298	6.739	2.239	4.047e-02	0.296	-3.982	BTNL9	butyrophilin-like 9	5	180399830	NM_152547	153579	5q35.3	Hs.546502	4	membrane integral to membrane
205308_at	0.225	5.909	2.239	4.049e-02	0.296	-3.982	FAM164A	family with sequence similarity 164, member A	8	79740836	NM_016010	51101	8q21.12	Hs.271876	6
209119_x_at	0.277	6.400	2.239	4.050e-02	0.296	-3.982	NR2F2	nuclear receptor subfamily 2, group F, member 2	15	94670160, 94675114, 94676797, 94677572	AV703465	7026	15q26	Hs.657455	27	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding
212709_at	-0.398	5.303	-2.239	4.051e-02	0.296	-3.983	NUP160	nucleoporin 160kDa	11	-47756245	D83781	23279	11p11.2	Hs.643526	16	kinetochore nucleocytoplasmic transporter activity protein binding nucleus mRNA export from nucleus protein transport Nup107-160 complex Nup107-160 complex intracellular protein transmembrane transport
218448_at	-0.300	6.705	-2.239	4.052e-02	0.296	-3.983	C20orf11	chromosome 20 open reading frame 11	20	61039885	NM_017896	54994	20q13.33	Hs.353013	7	protein binding nucleus
204959_at	0.332	4.125	2.239	4.053e-02	0.296	-3.983	MNDA	myeloid cell nuclear differentiation antigen	1	157067791	NM_002432	4332	1q22	Hs.153837	14	DNA binding protein binding nucleus cytoplasm cellular defense response regulation of transcription
241644_at	0.208	5.210	2.238	4.056e-02	0.296	-3.984	BOLA2	bolA homolog 2 (E. coli)	16	-30111756, -29372414	AW770588	552900	16p11.2	Hs.444600 Hs.655267	5
217864_s_at	-0.243	7.683	-2.238	4.057e-02	0.296	-3.984	PIAS1	protein inhibitor of activated STAT, 1	15	66133625	NM_016166	8554	15q	Hs.162458	67	DNA binding transcription coactivator activity transcription corepressor activity nucleus JAK-STAT cascade zinc ion binding nuclear speck SUMO ligase activity enzyme binding modification-dependent protein catabolic process androgen receptor signaling pathway positive regulation of protein sumoylation regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding androgen receptor binding	Ubiquitin mediated proteolysis Jak-STAT signaling pathway Pathways in cancer Small cell lung cancer
213933_at	0.251	4.517	2.238	4.058e-02	0.296	-3.984	PTGER3	prostaglandin E receptor 3 (subtype EP3)	1	-71244124, -71209051, -71190702, -71090623	AW242315	5733	1p31.2	Hs.445000	45	ligand-dependent nuclear receptor activity G-protein coupled receptor activity prostaglandin E receptor activity nuclear envelope plasma membrane integral to plasma membrane transcription, DNA-dependent signal transduction G-protein coupled receptor protein signaling pathway cell death	Calcium signaling pathway Neuroactive ligand-receptor interaction
1561687_a_at	0.305	2.935	2.238	4.059e-02	0.296	-3.984	ZNF382	zinc finger protein 382	19	41788060	BC038358	84911	19q13.12	Hs.631591	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
236656_s_at	-0.668	6.679	-2.238	4.061e-02	0.297	-3.985	LOC100130506	hypothetical protein LOC100130506	2		AW014647	100130506
213932_x_at	0.443	10.701	2.238	4.063e-02	0.297	-3.985	HLA-A	major histocompatibility complex, class I, A	6	30018309, 1358588, 1157055	AI923492	3105	6p21.3	Hs.181244 Hs.713441	857	Golgi membrane antigen processing and presentation of peptide antigen via MHC class I protein binding integral to plasma membrane immune response immune response membrane integral to membrane antigen processing and presentation early endosome membrane MHC class I receptor activity MHC class I protein complex interspecies interaction between organisms	Endocytosis Cell adhesion molecules (CAMs) Antigen processing and presentation Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
203075_at	-0.345	7.391	-2.237	4.064e-02	0.297	-3.985	SMAD2	SMAD family member 2	18	-43613464, -43613463, -43613463	AW151617	4087	18q21.1	Hs.12253 Hs.705764	206	mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol	Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer
209580_s_at	-0.433	6.790	-2.237	4.066e-02	0.297	-3.986	MBD4	methyl-CpG binding domain protein 4	3	-130632482	AF114784	8930	3q21-q22	Hs.35947	34	DNA binding satellite DNA binding endodeoxyribonuclease activity protein binding nucleus nucleolus base-excision repair response to DNA damage stimulus hydrolase activity depyrimidination	Base excision repair
227976_at	0.220	4.305	2.237	4.067e-02	0.297	-3.986	LOC644538	hypothetical protein LOC644538	X	133952633	AW242009	644538	Xq26.3	Hs.42239	1
207734_at	0.154	3.181	2.237	4.070e-02	0.297	-3.987	LAX1	lymphocyte transmembrane adaptor 1	1	202000906	NM_017773	54900	1q32.1	Hs.272794	10	inactivation of MAPK activity protein binding cytoplasm plasma membrane immune response intracellular signaling cascade integral to membrane protein kinase binding B cell activation SH2 domain binding membrane raft negative regulation of T cell activation
210895_s_at	0.186	4.144	2.236	4.071e-02	0.297	-3.987	CD86	CD86 molecule	3	123256910, 123279439	L25259	942	3q21	Hs.171182	97	protein binding plasma membrane immune response cell-cell signaling positive regulation of cell proliferation coreceptor activity integral to membrane transcription activator activity T cell activation positive regulation of lymphotoxin A biosynthetic process interspecies interaction between organisms positive regulation of interleukin-2 biosynthetic process positive regulation of interleukin-4 biosynthetic process positive regulation of T-helper 2 cell differentiation positive regulation of transcription	Cell adhesion molecules (CAMs) Toll-like receptor signaling pathway Type I diabetes mellitus Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease
1552347_at	-0.278	6.518	-2.236	4.071e-02	0.297	-3.987	CRYZL1	crystallin, zeta (quinone reductase)-like 1	21	-33883517	NM_145311	9946	21q21.3	Hs.352671	9	NADPH:quinone reductase activity binding cytosol zinc ion binding oxidoreductase activity quinone cofactor metabolic process NADP or NADPH binding oxidation reduction
204191_at	-0.253	4.908	-2.236	4.073e-02	0.297	-3.987	IFNAR1	interferon (alpha, beta and omega) receptor 1	21	33619083	NM_000629	3454	21q22.1 21q22.11	Hs.529400	71	receptor activity type I interferon receptor activity protein binding integral to plasma membrane cell surface receptor linked signal transduction JAK-STAT cascade response to virus membrane positive regulation of interferon-gamma production T cell activation type I interferon biosynthetic process	Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity
226816_s_at	-0.305	8.234	-2.236	4.075e-02	0.297	-3.988	KIAA1143	KIAA1143	3	-44765242	AI745170	57456	3p21.31	Hs.476082 Hs.604937	6
224299_x_at	0.209	5.439	2.236	4.075e-02	0.297	-3.988	FTCD	formiminotransferase cyclodeaminase	21	-46381121, -46380603	AF289023	10841	21q22.3	Hs.415846	11	folic acid binding cytoplasm Golgi apparatus histidine metabolic process folic acid and derivative metabolic process transferase activity lyase activity glutamate formimidoyltransferase activity formimidoyltetrahydrofolate cyclodeaminase activity cellular metabolic process	Histidine metabolism One carbon pool by folate Metabolic pathways
218346_s_at	-0.540	9.086	-2.236	4.075e-02	0.297	-3.988	SESN1	sestrin 1	6	-109414337	NM_014454	27244	6q21	Hs.591336	6	nucleus response to DNA damage stimulus cell cycle arrest negative regulation of cell proliferation	p53 signaling pathway
240199_x_at	0.217	5.890	2.236	4.075e-02	0.297	-3.988	ZNF345	zinc finger protein 345	19	42033106	AI016940	25850	19q13.12	Hs.362324	5	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity RNA polymerase III transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase III promoter zinc ion binding regulation of transcription metal ion binding
222217_s_at	0.195	5.431	2.236	4.076e-02	0.297	-3.988	SLC27A3	solute carrier family 27 (fatty acid transporter), member 3	1	152014391	BC003654	11000	1q21.3	Hs.438723	7	nucleotide binding mitochondrion lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity
203272_s_at	-0.246	7.534	-2.236	4.076e-02	0.297	-3.988	TUSC2	tumor suppressor candidate 2	3	-50337344	BF308548	11334	3p21.3	Hs.517981	11	protein binding cell cycle cell-cell signaling cell proliferation
214507_s_at	0.211	7.021	2.236	4.076e-02	0.297	-3.988	EXOSC2	exosome component 2	9	132558978	NM_014285	23404	9q34	Hs.654643	32	3'-5'-exoribonuclease activity exosome (RNase complex) exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing 7S RNA binding hydrolase activity	RNA degradation
226901_at	0.318	6.607	2.236	4.077e-02	0.297	-3.988	C17orf58	chromosome 17 open reading frame 58	17	-63417678	AI214996	284018	17q24.2	Hs.90790	2	protein binding
210285_x_at	-0.255	7.560	-2.236	4.078e-02	0.297	-3.988	WTAP	Wilms tumor 1 associated protein	6	160068141, 160068141, 160068609	BC000383	9589	6q25-q27	Hs.446091 Hs.710715	16	nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane
229356_x_at	-0.203	7.655	-2.236	4.078e-02	0.297	-3.988	INO80	INO80 homolog (S. cerevisiae)	15	-39058370	AK002176	54617	15q15.1	Hs.292949	12	nucleotide binding DNA binding DNA helicase activity ATP binding nucleus chromatin remodeling hydrolase activity ATPase activity
1569452_at	0.308	4.043	2.235	4.082e-02	0.297	-3.989	LOC692247	hypothetical locus LOC692247	11		BG772667	692247	11p15.5	Hs.560022	2
201475_x_at	0.390	7.310	2.235	4.083e-02	0.297	-3.989	MARS	methionyl-tRNA synthetase	12	56168117	NM_004990	4141	12q13.2	Hs.632707	18	tRNA binding nucleotide binding methionine-tRNA ligase activity protein binding ATP binding cytoplasm plasma membrane methionyl-tRNA aminoacylation ligase activity	Selenoamino acid metabolism Aminoacyl-tRNA biosynthesis
201201_at	0.429	9.750	2.235	4.085e-02	0.297	-3.990	CSTB	cystatin B (stefin B)	21	-44018258	NM_000100	1476	21q22.3	Hs.695	49	protease binding cysteine-type endopeptidase inhibitor activity protein binding intracellular nucleus nucleolus cytoplasm adult locomotory behavior negative regulation of peptidase activity
219041_s_at	-0.245	9.126	-2.235	4.085e-02	0.297	-3.990	REPIN1	replication initiator 1	7	149696811, 149699190	NM_014374	29803	7q36.1	Hs.647086	13	DNA binding intracellular nucleus nuclear origin of replication recognition complex DNA replication zinc ion binding metal ion binding
224439_x_at	-0.218	9.441	-2.235	4.086e-02	0.297	-3.990	RNF7	ring finger protein 7	3	142939740	BC005966	9616	3q22-q24	Hs.134623	25	copper ion binding protein binding nucleus cytoplasm anti-apoptosis redox signal response zinc ion binding induction of apoptosis by oxidative stress NEDD8 ligase activity modification-dependent protein catabolic process protein neddylation metal ion binding	Ubiquitin mediated proteolysis
212969_x_at	0.239	5.102	2.234	4.087e-02	0.297	-3.990	EML3	echinoderm microtubule associated protein like 3	11	-62126266	BE222618	256364	11q12.3	Hs.379785	8	protein binding cytoplasm microtubule
203645_s_at	0.644	5.290	2.234	4.087e-02	0.297	-3.990	CD163	CD163 molecule	12	-7514676	NM_004244	9332	12p13.3	Hs.504641	51	scavenger receptor activity protein binding extracellular region plasma membrane integral to plasma membrane acute-phase response inflammatory response
215250_at	0.325	5.473	2.234	4.088e-02	0.297	-3.990	TMEM111	transmembrane protein 111	3	-9980635	AU147317	55831	3p25.3	Hs.475392	6	molecular_function cellular_component biological_process membrane integral to membrane
240337_at	0.197	3.597	2.234	4.088e-02	0.297	-3.990	RHOA	ras homolog gene family, member A	3	-49371582	AW173151	387	3p21.3	Hs.247077 Hs.709788	348	nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation	Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer
228402_at	0.289	5.857	2.234	4.089e-02	0.297	-3.991	ZBED3	zinc finger, BED-type containing 3	5	-76408287	AI679968	84327	5q13.3	Hs.584988	5	DNA binding zinc ion binding metal ion binding
230977_at	0.167	6.985	2.234	4.091e-02	0.297	-3.991	NPM2	nucleophosmin/nucleoplasmin 2	8	21938299	AI016313	10361	8p21.3	Hs.131055	5	cytoplasmic chromatin nuclear chromatin nucleic acid binding nucleus chromatin remodeling regulation of exit from mitosis single fertilization embryonic development oocyte differentiation histone binding positive regulation of meiosis
1554241_at	-0.522	7.411	-2.234	4.091e-02	0.297	-3.991	COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	14	30413491	BC007230	1690	14q12-q13	Hs.21016	31	extracellular region proteinaceous extracellular matrix sensory perception of sound
241172_at	0.175	3.852	2.234	4.091e-02	0.297	-3.991	GRIA2	glutamate receptor, ionotropic, AMPA 2	4	158361185, 158361269	AI939470	2891	4q32-q33	Hs.32763	48	regulation of receptor recycling receptor activity alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity protein binding plasma membrane ion transport signal transduction response to lithium ion postsynaptic density kainate selective glutamate receptor activity integral to membrane cell junction PDZ domain binding growth cone synaptic vesicle membrane receptor internalization asymmetric synapse presynaptic membrane cell soma dendritic spine dendritic shaft protein complex establishment of protein localization postsynaptic membrane positive regulation of synaptic transmission regulation of synaptic transmission, glutamatergic	Neuroactive ligand-receptor interaction Long-term potentiation Long-term depression Amyotrophic lateral sclerosis (ALS)
244825_at	0.212	6.141	2.234	4.092e-02	0.297	-3.991	SHROOM4	shroom family member 4	X	-50351386	AI005420	57477	Xp11.22	Hs.420541	9	stress fiber protein binding cytoplasm actin filament organization multicellular organismal development brain development basal plasma membrane apical plasma membrane myosin II complex cortical actin cytoskeleton filamentous actin cognition actin filament binding
242114_at	-0.335	5.000	-2.234	4.092e-02	0.297	-3.991	BOLA2	bolA homolog 2 (E. coli)	16	-30111756, -29372414	BF088991	552900	16p11.2	Hs.444600 Hs.655267	5
231579_s_at	0.510	8.185	2.234	4.093e-02	0.297	-3.991	TIMP2	TIMP metallopeptidase inhibitor 2	17	-74360653	BE968786	7077	17q25	Hs.633514	168	enzyme inhibitor activity integrin binding protein binding extracellular region basement membrane enzyme activator activity metalloendopeptidase inhibitor activity negative regulation of cell proliferation cell surface regulation of cAMP metabolic process regulation of MAPKKK cascade regulation of neuron differentiation
1556804_s_at	0.351	2.600	2.234	4.094e-02	0.297	-3.992	POLR3B	polymerase (RNA) III (DNA directed) polypeptide B	12	105275565, 105275989	BC033542	55703	12q23.3	Hs.610795 Hs.62696	8	DNA binding DNA-directed RNA polymerase activity nucleus transcription zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase
226869_at	0.204	4.422	2.233	4.097e-02	0.297	-3.992	MEGF6	multiple EGF-like-domains 6	1	-3394365	AI655611	1953	1p36.3	Hs.593645	4	calcium ion binding extracellular region biological_process
220956_s_at	0.178	7.190	2.233	4.098e-02	0.297	-3.993	EGLN2	egl nine homolog 2 (C. elegans)	19	45996887, 45998020	NM_017555	112398	19q13.2	Hs.515417	35	regulation of cell growth response to hypoxia nucleus cytoplasm ferrous iron binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors oxygen sensor activity estrogen receptor signaling pathway L-ascorbic acid binding cell redox homeostasis positive regulation of protein catabolic process metal ion binding oxidation reduction
238021_s_at	-0.957	6.101	-2.233	4.098e-02	0.297	-3.993	CRNDE	colorectal neoplasia differentially expressed (non-protein coding)	16		AA954994	643911	16q12.2	Hs.237396	1
201561_s_at	0.237	6.914	2.233	4.099e-02	0.297	-3.993	CLSTN1	calsyntenin 1	1	-9711665	NM_014944	22883	1p36.22	Hs.29665	12	Golgi membrane calcium ion binding protein binding nucleus endoplasmic reticulum Golgi apparatus plasma membrane cell adhesion homophilic cell adhesion integral to membrane cell junction cell projection synapse postsynaptic membrane
209157_at	-0.363	8.941	-2.233	4.099e-02	0.297	-3.993	DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2	16	-45546774	AF011793	10294	16q12.1	Hs.368078	15	protein folding zinc ion binding positive regulation of cell proliferation membrane heat shock protein binding metal ion binding unfolded protein binding
210812_at	0.185	3.915	2.233	4.100e-02	0.297	-3.993	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	5	82409072	BC005259	7518	5q13-q14	Hs.567359	93	condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding nucleus nucleus cytosol DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development protein C-terminus binding response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA repair positive regulation of ligase activity	Non-homologous end-joining
205789_at	-0.190	3.467	-2.233	4.101e-02	0.297	-3.993	CD1D	CD1d molecule	1	156416360	NM_001766	912	1q22-q23	Hs.1799	84	receptor activity lysosomal membrane endosome plasma membrane integral to plasma membrane endosome membrane detection of bacterium antigen processing and presentation beta-2-microglobulin binding exogenous lipid antigen binding MHC class I protein complex interspecies interaction between organisms T cell selection positive regulation of innate immune response protein heterodimerization activity antigen processing and presentation, endogenous lipid antigen via MHC class Ib	Hematopoietic cell lineage
237247_at	0.266	2.893	2.232	4.102e-02	0.297	-3.994	USP51	ubiquitin specific peptidase 51	X	-55529686	AI341140	158880	Xp11.21	Hs.134289	9	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding
218181_s_at	-0.271	6.902	-2.232	4.104e-02	0.297	-3.994	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	2	101680919	NM_017792	9448	2q11.2-q12	Hs.719073	22	nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade transferase activity	MAPK signaling pathway
236461_at	0.504	5.424	2.232	4.105e-02	0.297	-3.994	ABHD1	abhydrolase domain containing 1	2	27200160	AI554273	84696	2p23.3	Hs.375791	6	molecular_function carboxylesterase activity biological_process membrane integral to membrane hydrolase activity
226244_at	0.234	6.993	2.232	4.105e-02	0.297	-3.994	CLEC14A	C-type lectin domain family 14, member A	14	-37793069	BF059395	161198	14q21.1	Hs.525307	5	binding sugar binding membrane integral to membrane
233844_at	-0.224	4.600	-2.232	4.106e-02	0.297	-3.994	CD99L2	CD99 molecule-like 2	X	-149685466	AK023776	83692	Xq28	Hs.522805	8	protein binding plasma membrane cell adhesion integral to membrane cell junction
243602_at	0.204	3.058	2.232	4.106e-02	0.297	-3.994	MGC40069	hypothetical protein MGC40069	14		AI684979	348035	14q11.2	Hs.369380	6
211073_x_at	0.614	10.063	2.232	4.106e-02	0.297	-3.994	RPL3	ribosomal protein L3	22	-38038832	BC006483	6122	22q13	Hs.119598	24	RNA binding structural constituent of ribosome protein binding intracellular nucleolus cytoplasm cytosol ribosome translational elongation cytosolic large ribosomal subunit	Ribosome
1558711_at	-0.233	5.749	-2.232	4.107e-02	0.297	-3.994	FAM13AOS	FAM13A opposite strand (non-protein coding)	4	89849962	AI537367	285512	4q22.1	Hs.715606	3
238778_at	-0.556	7.409	-2.232	4.107e-02	0.297	-3.994	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	10	-28379928	AI244661	143098	10p12.1	Hs.499159	5	protein binding adherens junction tight junction membrane cell junction
1552610_a_at	-0.427	6.479	-2.232	4.107e-02	0.297	-3.994	JAK1	Janus kinase 1	1	-65071493	NM_002227	3716	1p32.3-p31.3	Hs.207538	118	nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity growth hormone receptor binding protein binding ATP binding nucleus cytoplasm cytoskeleton enzyme linked receptor protein signaling pathway protein kinase cascade membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway response to antibiotic	Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer
1553757_at	0.220	5.085	2.232	4.110e-02	0.298	-3.995	IQCG	IQ motif containing G	3	-199100344, -199100343	NM_032263	84223	3q29	Hs.591675	6
224599_at	-0.360	8.419	-2.231	4.111e-02	0.298	-3.995	CGGBP1	CGG triplet repeat binding protein 1	3	-88183789	BF979809	8545	3p12-p11.1	Hs.444818	14	DNA binding double-stranded DNA binding nucleus regulation of transcription
214980_at	-0.210	5.575	-2.231	4.112e-02	0.298	-3.996	UBE3A	ubiquitin protein ligase E3A	15	-23133488, -23133488, -23133488	AF037219	7337	15q11-q13	Hs.598862	76	ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms	Ubiquitin mediated proteolysis
214470_at	0.239	4.961	2.231	4.114e-02	0.298	-3.996	KLRB1	killer cell lectin-like receptor subfamily B, member 1	12	-9639136	NM_002258	3820	12p13	Hs.169824	25	transmembrane receptor activity binding sugar binding plasma membrane cell surface receptor linked signal transduction integral to membrane
205483_s_at	0.276	6.601	2.231	4.115e-02	0.298	-3.996	ISG15	ISG15 ubiquitin-like modifier	1	938709	NM_005101	9636	1p36.33	Hs.458485	61	protein binding extracellular region extracellular space cytoplasm cell-cell signaling response to virus modification-dependent protein catabolic process protein tag ISG15-protein conjugation interspecies interaction between organisms	RIG-I-like receptor signaling pathway
229441_at	-0.338	5.489	-2.231	4.118e-02	0.298	-3.997	PRSS23	protease, serine, 23	11	86189138	AI569872	11098	11q14.1	Hs.25338	13	serine-type endopeptidase activity extracellular region nucleus proteolysis peptidase activity
231899_at	-0.416	7.558	-2.231	4.118e-02	0.298	-3.997	ZC3H12C	zinc finger CCCH-type containing 12C	11	109469296	AB051513	85463	11q22.3	Hs.376289	3	magnesium ion binding endonuclease activity zinc ion binding hydrolase activity
221519_at	-0.245	7.992	-2.230	4.119e-02	0.298	-3.997	FBXW4	F-box and WD repeat domain containing 4	10	-103360410	AF281859	6468	10q24	Hs.500822	16	ubiquitin ligase complex molecular_function ubiquitin-dependent protein catabolic process multicellular organismal development Wnt receptor signaling pathway embryonic limb morphogenesis limb development
202171_at	-0.436	8.387	-2.230	4.119e-02	0.298	-3.997	VEZF1	vascular endothelial zinc finger 1	17	-53403908	AU146275	7716	17q22	Hs.463569	3	angiogenesis endothelial cell development DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter cellular defense response zinc ion binding regulation of transcription metal ion binding
37408_at	0.349	7.716	2.230	4.119e-02	0.298	-3.997	MRC2	mannose receptor, C type 2	17	58058493	AB014609	9902	17q23.2	Hs.7835	23	receptor activity binding calcium ion binding sugar binding endocytosis membrane integral to membrane
204460_s_at	-0.290	7.142	-2.230	4.120e-02	0.298	-3.997	RAD1	RAD1 homolog (S. pombe)	5	-34941124, -34941122	AF074717	5810	5p13.2	Hs.38114	44	cell cycle checkpoint DNA damage checkpoint damaged DNA binding protein binding nucleus DNA replication DNA repair response to DNA damage stimulus meiotic prophase I 3'-5' exonuclease activity 3'-5' exonuclease activity exodeoxyribonuclease III activity hydrolase activity
240369_at	0.244	3.281	2.230	4.120e-02	0.298	-3.997	TTC7A	tetratricopeptide repeat domain 7A	2	47021816	AW195569	57217	2p21	Hs.370603	7	binding
200657_at	0.467	8.244	2.230	4.122e-02	0.298	-3.998	SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	X	118486390	NM_001152	292	Xq24-q26	Hs.632282	23	transporter activity binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane integral to plasma membrane transport adenine transmembrane transporter activity membrane mitochondrial nucleoid interspecies interaction between organisms	Calcium signaling pathway Parkinson's disease Huntington's disease
202430_s_at	0.366	5.541	2.230	4.124e-02	0.298	-3.998	PLSCR1	phospholipid scramblase 1	3	-147715656	NM_021105	5359	3q23	Hs.130759	34	calcium ion binding protein binding plasma membrane response to virus integral to membrane phospholipid scrambling SH3 domain binding phospholipid scramblase activity platelet activation
218238_at	-0.382	6.646	-2.229	4.129e-02	0.298	-3.999	GTPBP4	GTP binding protein 4	10	1024348	NM_012341	23560	10p15-p14	Hs.215766	10	regulation of cyclin-dependent protein kinase activity nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization
1557642_at	0.171	2.092	2.229	4.132e-02	0.298	-4.000	LOC100129258	hypothetical protein LOC100129258	2		AK090907	100129258	2q37.2	Hs.591594	1
215106_at	0.222	4.080	2.229	4.132e-02	0.298	-4.000	TTC22	tetratricopeptide repeat domain 22	1	-55022811, -55019339	AI923972	55001	1p32.3	Hs.16230	3	binding
208699_x_at	0.346	4.963	2.229	4.133e-02	0.298	-4.000	TKT	transketolase	3	-53234694, -53233763	BF696840	7086	3p14.3	Hs.89643	24	transketolase activity transketolase activity calcium ion binding protein binding cytosol metabolic process transferase activity regulation of growth	Pentose phosphate pathway Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of plant hormones Metabolic pathways
1562209_at	-0.244	3.275	-2.228	4.135e-02	0.299	-4.001	DCAF4L1	DDB1 and CUL4 associated factor 4-like 1	4	41678469	BU561160	285429	4p13	Hs.213307	3
1563111_a_at	-0.327	6.583	-2.228	4.136e-02	0.299	-4.001	PIGX	phosphatidylinositol glycan anchor biosynthesis, class X	3	197923642	AK000529	54965	3q29	Hs.223296	6	endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane preassembly of GPI anchor in ER membrane	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
229277_at	0.287	4.517	2.228	4.138e-02	0.299	-4.001	ADRB1	adrenergic, beta-1-, receptor	10	115793795	T96352	153	10q24-q26	Hs.99913	184	positive regulation of heart rate by epinephrine-norepinephrine positive regulation of the force of heart contraction by epinephrine-norepinephrine diet induced thermogenesis vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure receptor activity G-protein coupled receptor activity beta1-adrenergic receptor activity protein binding membrane fraction plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway response to cold heat generation negative regulation of multicellular organism growth fear response brown fat cell differentiation	Calcium signaling pathway Neuroactive ligand-receptor interaction Endocytosis Gap junction
1560099_at	-0.402	3.141	-2.228	4.139e-02	0.299	-4.001	LOC339260	hypothetical protein LOC339260	17		BC041488	339260	17p11.2	Hs.661076	1
204373_s_at	-0.400	7.981	-2.228	4.139e-02	0.299	-4.001	CEP350	centrosomal protein 350kDa	1	178190530	NM_014810	9857	1p36.13-q41	Hs.413045	17	nucleus centrosome spindle
221223_x_at	-0.893	6.890	-2.228	4.140e-02	0.299	-4.001	CISH	cytokine inducible SH2-containing protein	3	-50618889	NM_013324	1154	3p21.3	Hs.655334	29	regulation of cell growth molecular_function protein binding cellular_component plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway intracellular signaling cascade negative regulation of signal transduction modification-dependent protein catabolic process	Jak-STAT signaling pathway
242006_at	-0.246	3.691	-2.228	4.141e-02	0.299	-4.002	LCA5	Leber congenital amaurosis 5	6	-80251426, -80251426	AI379143	167691	6q14.1	Hs.21945	10	cytoplasm cytoskeleton cilium microtubule basal body protein transport cilium axoneme
208511_at	0.272	3.037	2.227	4.142e-02	0.299	-4.002	PTTG3P	pituitary tumor-transforming 3 (pseudogene)	8	-67842185	NM_021000	26255	8q13.1	Hs.647156	2	nucleus cytoplasm DNA metabolic process SH3 domain binding chromosome organization
220120_s_at	0.249	2.656	2.227	4.144e-02	0.299	-4.002	EPB41L4A	erythrocyte membrane protein band 4.1 like 4A	5	-111526213	NM_022140	64097	5q22.1-q22.2	Hs.584954	7	binding cellular_component cytoplasm cytoskeleton cytoskeletal protein binding biological_process extrinsic to membrane
221913_at	0.161	6.733	2.227	4.145e-02	0.299	-4.003	SIRT3	sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)	11	-205029	AI492888	23410	11p15.5	Hs.716456	21	NAD+ ADP-ribosyltransferase activity protein binding cytoplasm mitochondrion mitochondrial matrix chromatin silencing protein amino acid ADP-ribosylation protein amino acid deacetylation zinc ion binding membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides regulation of transcription metal ion binding NAD binding
226678_at	0.242	6.434	2.227	4.146e-02	0.299	-4.003	UNC13D	unc-13 homolog D (C. elegans)	17	-71334901	BG054744	201294	17q25.1	Hs.41045	21	granuloma formation germinal center formation cytoplasm exocytosis phagocytosis membrane natural killer cell degranulation defense response to virus
227604_at	-0.225	5.431	-2.227	4.146e-02	0.299	-4.003	LOC151146	hypothetical protein LOC151146	2		BG292251	151146	2q14.2	Hs.593852	2
1555332_at	-0.247	2.884	-2.227	4.146e-02	0.299	-4.003	TPH2	tryptophan hydroxylase 2	12	70618892	AY098914	121278	12q21.1	Hs.376337	112	tryptophan 5-monooxygenase activity iron ion binding serotonin biosynthetic process from tryptophan aromatic amino acid family metabolic process amino acid binding metal ion binding oxidation reduction	Tryptophan metabolism Biosynthesis of alkaloids derived from shikimate pathway Metabolic pathways
241762_at	-1.012	8.173	-2.227	4.147e-02	0.299	-4.003	FBXO32	F-box protein 32	8	-124584538, -124584538	BF244402	114907	8q24.13	Hs.403933	17	protein binding modification-dependent protein catabolic process
225113_at	-0.383	6.104	-2.226	4.151e-02	0.299	-4.004	AGPS	alkylglycerone phosphate synthase	2	177965716	BF688144	8540	2q31.2	Hs.516543	19	peroxisome peroxisomal membrane cytosol alkylglycerone-phosphate synthase activity lipid biosynthetic process membrane oxidoreductase activity transferase activity FAD binding	Ether lipid metabolism Metabolic pathways
203098_at	-0.276	6.865	-2.226	4.152e-02	0.299	-4.004	CDYL	chromodomain protein, Y-like	6	4651391, 4721678, 4781330, 4835224	AL050164	9425	6p25.1	Hs.269092	8	chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription
219718_at	0.418	7.890	2.226	4.153e-02	0.299	-4.004	FGGY	FGGY carbohydrate kinase domain containing	1	59535212	NM_018291	55277	1p32.1	Hs.444301	7	molecular_function cellular_component carbohydrate metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor neuron maintenance
205251_at	-0.759	7.774	-2.226	4.153e-02	0.299	-4.004	PER2	period homolog 2 (Drosophila)	2	-238817417	NM_022817	8864	2q37.3	Hs.58756	46	signal transducer activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm	Circadian rhythm - mammal
213994_s_at	0.166	2.463	2.226	4.154e-02	0.299	-4.005	SPON1	spondin 1, extracellular matrix protein	11	13940489	AI885290	10418	11p15.2	Hs.705394	15	protein binding extracellular region proteinaceous extracellular matrix cell adhesion
239615_at	0.398	5.816	2.226	4.155e-02	0.299	-4.005	SLC22A5	solute carrier family 22 (organic cation/carnitine transporter), member 5	5	131733299	AI768445	6584	5q31	Hs.443572	89	nucleotide binding protein binding ATP binding plasma membrane ion transport sodium ion transport ion transmembrane transporter activity carnitine transporter activity carnitine transporter activity drug transporter activity symporter activity quaternary ammonium group transport carnitine transport carnitine transport drug transport integral to membrane apical plasma membrane PDZ domain binding sodium ion binding brush border membrane brush border membrane quorum sensing during interaction with host positive regulation of intestinal epithelial structure maintenance sodium-dependent organic cation transport
218940_at	-0.600	6.340	-2.226	4.156e-02	0.299	-4.005	C14orf138	chromosome 14 open reading frame 138	14	-49645099	NM_024558	79609	14q21.3	Hs.558541	3
202551_s_at	-0.748	7.320	-2.226	4.157e-02	0.299	-4.005	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	2	36436900	BG546884	51232	2p21	Hs.699247	9	regulation of cell growth enzyme inhibitor activity serine-type endopeptidase inhibitor activity insulin-like growth factor receptor activity insulin-like growth factor binding extracellular region plasma membrane nervous system development integral to membrane
226653_at	0.289	4.608	2.225	4.160e-02	0.299	-4.006	MARK1	MAP/microtubule affinity-regulating kinase 1	1	218768190	AB040910	4139	1q41	Hs.497806	27	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm protein amino acid phosphorylation cytoskeleton organization protein kinase cascade microtubule cytoskeleton transferase activity
205542_at	0.427	5.099	2.225	4.161e-02	0.299	-4.006	STEAP1	six transmembrane epithelial antigen of the prostate 1	7	89621624	NM_012449	26872	7q21	Hs.61635	12	transporter activity iron ion binding copper ion binding endosome plasma membrane integral to plasma membrane cell-cell junction ion transport iron ion transport electron carrier activity channel activity oxidoreductase activity electron transport chain metal ion binding FAD binding
244128_x_at	0.254	5.599	2.225	4.161e-02	0.299	-4.006	GLIS1	GLIS family zinc finger 1	1	-53744493	AA872588	148979	1p32.3	Hs.306691	6	negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus nucleolus cytoplasm zinc ion binding positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding
221739_at	0.185	6.780	2.224	4.166e-02	0.299	-4.007	C19orf10	chromosome 19 open reading frame 10	19	-4608556	AL524093	56005	19p13.3	Hs.465645	10	protein binding extracellular region ER-Golgi intermediate compartment growth factor activity positive regulation of cell proliferation
205364_at	0.704	5.675	2.224	4.167e-02	0.299	-4.007	ACOX2	acyl-Coenzyme A oxidase 2, branched chain	3	-58465903	NM_003500	8309	3p14.3	Hs.444959	6	acyl-CoA dehydrogenase activity acyl-CoA oxidase activity peroxisome lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation bile acid metabolic process electron carrier activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity FAD binding oxidation reduction	Primary bile acid biosynthesis Metabolic pathways PPAR signaling pathway
1557801_x_at	-0.238	5.674	-2.224	4.167e-02	0.299	-4.007	C11orf31	chromosome 11 open reading frame 31	11	57265297	AF085883	280636	11q12.1	Hs.655373 Hs.719147	6	selenium binding cell redox homeostasis
226734_at	-0.398	6.631	-2.224	4.167e-02	0.299	-4.007	EIF4E2	eukaryotic translation initiation factor 4E family member 2	2	233123600	AW242220	9470	2q37.1	Hs.292026 Hs.700929	15	RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation	mTOR signaling pathway Insulin signaling pathway
216913_s_at	-0.530	5.758	-2.224	4.168e-02	0.299	-4.008	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	10	-99106448	AK021460	23223	10q24.1	Hs.434251	15	protein binding nucleus nucleolus membrane integral to membrane
200938_s_at	0.194	4.865	2.224	4.169e-02	0.299	-4.008	RERE	arginine-glutamic acid dipeptide (RE) repeats	1	-8335050, -8335050	AI920976	473	1p36.2-p36.1	Hs.463041	17	histone deacetylase complex transcription factor activity nucleus chromatin remodeling regulation of transcription, DNA-dependent NLS-bearing substrate import into nucleus multicellular organismal development poly-glutamine tract binding zinc ion binding sequence-specific DNA binding metal ion binding
201550_x_at	0.416	10.689	2.224	4.170e-02	0.299	-4.008	ACTG1	actin, gamma 1	17	-77091593	NM_001614	71	17q25	Hs.514581	102	nucleotide binding structural constituent of cytoskeleton ATP binding cytoplasm cytoskeleton cell motion identical protein binding response to calcium ion	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
239952_at	-0.264	5.603	-2.224	4.170e-02	0.299	-4.008	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	AI743662	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
214467_at	0.182	3.833	2.224	4.171e-02	0.299	-4.008	GPR65	G protein-coupled receptor 65	14	87541248	NM_003608	8477	14q31-q32.1	Hs.513440	10	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane apoptosis immune response signal transduction G-protein coupled receptor protein signaling pathway multicellular organismal development
220731_s_at	0.222	6.082	2.223	4.174e-02	0.300	-4.009	NECAP2	NECAP endocytosis associated 2	1	16639753	NM_018090	55707	1p36.13	Hs.437385 Hs.710158	16	intracellular plasma membrane coated pit endocytosis protein transport clathrin vesicle coat cytoplasmic vesicle
211520_s_at	0.159	2.247	2.223	4.175e-02	0.300	-4.009	GRIA1	glutamate receptor, ionotropic, AMPA 1	5	152850276	M64752	2890	5q31.1 5q33	Hs.519693	58	receptor activity ion channel activity extracellular-glutamate-gated ion channel activity membrane fraction endoplasmic reticulum plasma membrane ion transport signal transduction synaptic transmission kainate selective glutamate receptor activity integral to membrane cell junction alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction Long-term potentiation Long-term depression Amyotrophic lateral sclerosis (ALS)
223592_s_at	-0.332	6.890	-2.223	4.178e-02	0.300	-4.010	RNF135	ring finger protein 135	17	26322081	BC005084	84282	17q11.2	Hs.29874	12	protein binding zinc ion binding metal ion binding
204766_s_at	0.228	5.959	2.223	4.179e-02	0.300	-4.010	NUDT1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	7	2248382, 2248421, 2249065	NM_002452	4521	7p22	Hs.534331	46	GTPase activity protein binding cytoplasm DNA repair response to oxidative stress 8-oxo-7,8-dihydroguanine triphosphatase activity hydrolase activity
223703_at	0.400	5.384	2.223	4.180e-02	0.300	-4.010	C10orf11	chromosome 10 open reading frame 11	10	77212524	AF267860	83938	10q22.2-q22.3	Hs.118161	2	protein binding
201925_s_at	-0.445	8.141	-2.223	4.181e-02	0.300	-4.010	CD55	CD55 molecule, decay accelerating factor for complement (Cromer blood group)	1	205561439	NM_000574	1604	1q32	Hs.126517	118	soluble fraction plasma membrane integral to plasma membrane complement activation, classical pathway elevation of cytosolic calcium ion concentration anchored to membrane innate immune response membrane raft respiratory burst	Complement and coagulation cascades Hematopoietic cell lineage
210823_s_at	0.269	5.292	2.222	4.182e-02	0.300	-4.010	PTPRS	protein tyrosine phosphatase, receptor type, S	19	-5156518	U40317	5802	19p13.3	Hs.644384	23	receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation cell adhesion membrane hydrolase activity
209974_s_at	-0.295	7.931	-2.222	4.183e-02	0.300	-4.011	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	10	124903749	AF047473	9184	10q26	Hs.418533	28	kinetochore protein binding nucleus nucleolus cytosol mitosis mitotic cell cycle checkpoint cell proliferation anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Cell cycle
213547_at	-0.244	10.366	-2.222	4.183e-02	0.300	-4.011	CAND2	cullin-associated and neddylation-dissociated 2 (putative)	3	12813170	AB014567	23066	3p25.2	Hs.343664	7	intracellular nucleus transcription activator activity TATA-binding protein binding modification-dependent protein catabolic process regulation of transcription
226221_at	-0.340	6.172	-2.222	4.183e-02	0.300	-4.011	KIAA1432	KIAA1432	9	5619326, 5646582	AL138104	57589	9p24.1	Hs.211520	5	membrane integral to membrane
1555715_a_at	-0.203	5.464	-2.222	4.183e-02	0.300	-4.011	HRH3	histamine receptor H3	20	-60223411	AF346903	11255	20q13.33	Hs.251399	26	receptor activity G-protein coupled receptor activity histamine receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger negative regulation of adenylate cyclase activity neurotransmitter secretion	Neuroactive ligand-receptor interaction
212656_at	0.247	8.024	2.222	4.185e-02	0.300	-4.011	TSFM	Ts translation elongation factor, mitochondrial	12	56462802	AF110399	10102	12q13-q14	Hs.632704	10	transcription elongation regulator activity translation elongation factor activity intracellular nucleus mitochondrion translational elongation
231517_at	0.233	4.146	2.222	4.185e-02	0.300	-4.011	ZYG11A	zyg-11 homolog A (C. elegans)	1	53080770	AW243917	440590	1p32.3	Hs.658458	1	binding modification-dependent protein catabolic process
200645_at	0.216	11.131	2.222	4.187e-02	0.300	-4.012	GABARAP	GABA(A) receptor-associated protein	17	-7084461	NM_007278	11337	17p13.1	Hs.647421	38	Golgi membrane microtubule cytoskeleton organization autophagic vacuole membrane protein binding cytoplasm lysosome smooth endoplasmic reticulum Golgi apparatus microtubule microtubule associated complex plasma membrane protein targeting synaptic transmission microtubule binding protein transport actin cytoskeleton beta-tubulin binding GABA receptor binding	Regulation of autophagy
204601_at	-0.310	5.473	-2.222	4.187e-02	0.300	-4.012	N4BP1	NEDD4 binding protein 1	16	-47130137	NM_014664	9683	16q12.1	Hs.511839	6	nucleus
222737_s_at	-0.226	8.053	-2.222	4.188e-02	0.300	-4.012	BRD7	bromodomain containing 7	16	-48910441	AI674162	29117	16q12	Hs.437894	22	nucleus cytoplasm regulation of transcription from RNA polymerase II promoter transcription factor binding Wnt receptor signaling pathway histone binding
219455_at	-0.227	5.015	-2.222	4.188e-02	0.300	-4.012	C7orf63	chromosome 7 open reading frame 63	7	89712423	NM_024788	79846	7q21.13	Hs.657403	4	binding
212200_at	-0.435	5.090	-2.222	4.189e-02	0.300	-4.012	ANKLE2	ankyrin repeat and LEM domain containing 2	12	-131812326	AK025933	23141	12q24.33	Hs.654628	8	nuclear envelope membrane integral to membrane
206719_at	-0.238	3.779	-2.221	4.191e-02	0.300	-4.012	SYNGR4	synaptogyrin 4	19	53559468	NM_012451	23546	19q13.3	Hs.408333	3	membrane integral to membrane
217836_s_at	-0.434	8.058	-2.221	4.191e-02	0.300	-4.012	YY1AP1	YY1 associated protein 1	1	-153895869, -153895856	NM_018253	55249	1q22	Hs.584927	19	protein binding nucleus cytoplasm
212484_at	-0.351	8.556	-2.221	4.192e-02	0.300	-4.013	FAM89B	family with sequence similarity 89, member B	11	65096395	BF974389	23625	11q23	Hs.25723	7
210645_s_at	-0.335	8.391	-2.221	4.192e-02	0.300	-4.013	TTC3	tetratricopeptide repeat domain 3	21	37367440, 37377116	D83077	7267	21q22.2	Hs.368214	9	protein binding cellular_component vacuole biological_process zinc ion binding negative regulation of cell morphogenesis involved in differentiation negative regulation of neuron differentiation metal ion binding response to protein stimulus
221816_s_at	0.306	7.470	2.221	4.193e-02	0.300	-4.013	PHF11	PHD finger protein 11	13	48967801, 48968528	BF055474	51131	13q14.2	Hs.369039	17	protein binding zinc ion binding metal ion binding
232842_at	-0.213	3.868	-2.221	4.194e-02	0.300	-4.013	DOCK8	dedicator of cytokinesis 8	9	204864	AL161725	81704	9p24.3	Hs.132599	11	guanyl-nucleotide exchange factor activity GTP binding GTPase binding
232599_at	0.550	4.447	2.220	4.198e-02	0.300	-4.014	EXOC6	exocyst complex component 6	10	94584449, 94598204	AF220217	54536	10q23.33	Hs.655657	8	exocyst vesicle docking during exocytosis protein transport
212628_at	-0.401	6.376	-2.220	4.201e-02	0.300	-4.014	PKN2	protein kinase N2	1	88922509	BG292065	5586	1p22.2	Hs.440833	32	nucleotide binding protein kinase C activity ATP binding intracellular nucleus cytoplasm protein amino acid phosphorylation signal transduction transferase activity
224740_at	-0.359	6.749	-2.220	4.202e-02	0.300	-4.015	C5orf43	chromosome 5 open reading frame 43	5	-60489292	BE613001	643155	5q12.1	Hs.508479	2	membrane integral to membrane
204606_at	0.196	5.920	2.220	4.203e-02	0.300	-4.015	CCL21	chemokine (C-C motif) ligand 21	9	-34699001	NM_002989	6366	9p13	Hs.57907	54	extracellular region extracellular space chemotaxis inflammatory response immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
202964_s_at	-0.272	6.547	-2.220	4.203e-02	0.300	-4.015	RFX5	regulatory factor X, 5 (influences HLA class II expression)	1	-149579739	NM_000449	5993	1q21	Hs.632472	27	negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent	Antigen processing and presentation Primary immunodeficiency
1560339_s_at	-0.339	7.722	-2.220	4.204e-02	0.300	-4.015	NAP1L4	nucleosome assembly protein 1-like 4	11	-2922235	AK095320	4676	11p15.5	Hs.501684 Hs.695395	12	nucleus chromatin assembly complex cytoplasm nucleosome assembly unfolded protein binding
233662_at	-0.164	1.986	-2.220	4.205e-02	0.300	-4.015	CDH26	cadherin-like 26	20	57966876, 58004823	AL109928	60437	20q13.2-q13.33	Hs.54973	4	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane
220524_at	0.206	4.628	2.220	4.205e-02	0.300	-4.015	EPB41L4B	erythrocyte membrane protein band 4.1 like 4B	9	-111041832, -110974074	NM_024823	54566	9q31-q32	Hs.591901	4	structural constituent of cytoskeleton binding cytoplasm cytoskeleton cytoskeletal protein binding extrinsic to membrane
231757_at	-0.187	4.804	-2.219	4.210e-02	0.301	-4.016	TAS2R5	taste receptor, type 2, member 5	7	141136485	NM_018980	54429	7q31.3-q32	Hs.675370	16	receptor activity signal transduction G-protein coupled receptor protein signaling pathway chemosensory behavior taste receptor activity membrane integral to membrane response to stimulus sensory perception of taste	Taste transduction
229750_at	0.224	6.359	2.219	4.210e-02	0.301	-4.016	POU2F2	POU class 2 homeobox 2	19	-47284505	BF510728	5452	19q13.2	Hs.654420	37	transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter humoral immune response sequence-specific DNA binding
228758_at	-1.339	8.403	-2.219	4.210e-02	0.301	-4.016	BCL6	B-cell CLL/lymphoma 6	3	-188921858, -188921858, -188921858	AW264036	604	3q27	Hs.478588	139	protein import into nucleus, translocation negative regulation of transcription from RNA polymerase II promoter cell morphogenesis negative regulation of cell-matrix adhesion regulation of germinal center formation negative regulation of T-helper 2 type immune response negative regulation of B cell apoptosis transcription factor activity protein binding intracellular nucleus replication fork response to DNA damage stimulus spermatogenesis protein localization zinc ion binding negative regulation of cell proliferation transcription repressor activity transcription repressor activity actin cytoskeleton organization B cell differentiation negative regulation of cell growth positive regulation of B cell proliferation chromatin DNA binding regulation of Rho GTPase activity negative regulation of mast cell cytokine production negative regulation of Rho protein signal transduction positive regulation of apoptosis negative regulation of apoptosis regulation of memory T cell differentiation sequence-specific DNA binding regulation of transcription negative regulation of cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of S phase of mitotic cell cycle metal ion binding negative regulation of isotype switching to IgE isotypes erythrocyte development regulation of inflammatory response positive regulation of cell motion
204966_at	0.234	4.693	2.219	4.212e-02	0.301	-4.017	BAI2	brain-specific angiogenesis inhibitor 2	1	-31965304	NM_001703	576	1p35	Hs.524138	11	plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane brain-specific angiogenesis inhibitor activity brain-specific angiogenesis inhibitor activity
217371_s_at	-0.521	4.247	-2.219	4.212e-02	0.301	-4.017	IL15	interleukin 15	4	142777203	Y09908	3600	4q31	Hs.654378	180	signal transducer activity cytokine activity cytokine receptor binding protein binding extracellular region extracellular space membrane fraction nucleus cytoplasm endosome Golgi apparatus integral to plasma membrane immune response signal transduction cell-cell signaling positive regulation of cell proliferation	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
204445_s_at	0.243	4.289	2.218	4.215e-02	0.301	-4.017	ALOX5	arachidonate 5-lipoxygenase	10	45189634	AI361850	240	10q11.2	Hs.89499	141	arachidonate 5-lipoxygenase activity iron ion binding calcium ion binding protein binding nucleus nuclear envelope lumen cytoplasm cytosol inflammatory response membrane lipoxygenase activity nuclear matrix oxidoreductase activity leukotriene biosynthetic process nuclear membrane oxidation reduction	Arachidonic acid metabolism Linoleic acid metabolism Metabolic pathways
210150_s_at	0.197	6.357	2.218	4.218e-02	0.301	-4.018	LAMA5	laminin, alpha 5	20	-60317515	BC003355	3911	20q13.2-q13.3	Hs.473256	61	receptor binding structural molecule activity extracellular region basement membrane laminin-1 complex regulation of cell adhesion regulation of cell migration substrate adhesion-dependent cell spreading laminin-10 complex laminin-11 complex regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
221526_x_at	-0.337	7.257	-2.218	4.218e-02	0.301	-4.018	PARD3	par-3 partitioning defective 3 homolog (C. elegans)	10	-34440102	AW452651	56288	10p11.21	Hs.131489	40	protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction	Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction
1555304_a_at	0.184	3.399	2.218	4.218e-02	0.301	-4.018	KCNH5	potassium voltage-gated channel, subfamily H (eag-related), member 5	14	-62248710, -62243697	AF493798	27133	14q23.1	Hs.27043	12	two-component sensor activity two-component signal transduction system (phosphorelay) voltage-gated ion channel activity voltage-gated potassium channel activity calmodulin binding regulation of transcription, DNA-dependent ion transport potassium ion transport membrane integral to membrane potassium ion binding
243579_at	0.323	7.449	2.218	4.219e-02	0.301	-4.018	MSI2	musashi homolog 2 (Drosophila)	17	52688929, 52689372	BF029215	124540	17q22	Hs.658922	7	nucleotide binding RNA binding cytoplasm
235067_at	-0.364	6.451	-2.218	4.219e-02	0.301	-4.018	MKLN1	muskelin 1, intracellular mediator containing kelch motifs	7	130445394, 130663134	D81987	4289	7q32	Hs.44693	13	protein binding cytoplasm signal transduction
219652_s_at	0.197	5.679	2.218	4.220e-02	0.301	-4.018	CXorf36	chromosome X open reading frame 36	X	-44906499, -44892561	NM_024689	79742	Xp11.3	Hs.98321	8	extracellular region
203694_s_at	-0.235	7.166	-2.218	4.222e-02	0.301	-4.019	DHX16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	6	-30728885, -2069456, -1867754	NM_003587	8449	6p21.3	Hs.485060	9	nucleotide binding nucleic acid binding RNA helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity
218962_s_at	0.195	6.525	2.217	4.222e-02	0.301	-4.019	TMEM168	transmembrane protein 168	7	-112193022	NM_022484	64418	7q31.32	Hs.709689	7	membrane integral to membrane transport vesicle
243851_at	-0.232	3.233	-2.217	4.223e-02	0.301	-4.019	RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	1	-218388232	AI860647	25782	1q41	Hs.654849 Hs.708165	14	GTPase activator activity protein binding soluble fraction cytoplasm intracellular protein transport regulation of GTPase activity protein heterodimerization activity
227562_at	-0.500	7.106	-2.217	4.223e-02	0.301	-4.019	MAPKSP1	MAPK scaffold protein 1	4	-101018517	AI335267	8649	4q23	Hs.716375	22	activation of MAPKK activity protein binding late endosome membrane kinase activator activity	MAPK signaling pathway
232087_at	0.262	4.906	2.217	4.225e-02	0.301	-4.019	CXorf23	chromosome X open reading frame 23	X	-19844038	AW628045	256643	Xp22.12	Hs.28896	2	mitochondrion
210889_s_at	0.474	4.702	2.217	4.225e-02	0.301	-4.020	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	1	159899563	M31933	2213	1q23	Hs.654395	95	receptor activity protein binding plasma membrane plasma membrane immune response signal transduction integral to membrane IgG binding interspecies interaction between organisms	B cell receptor signaling pathway Fc gamma R-mediated phagocytosis Systemic lupus erythematosus
235351_at	0.188	2.624	2.217	4.225e-02	0.301	-4.020	TTLL7	tubulin tyrosine ligase-like family, member 7	1	-84107644	BF966240	79739	1p31.1	Hs.445826	7	tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process multicellular organismal development nervous system development ligase activity cell differentiation dendrite perikaryon
203690_at	-0.432	6.280	-2.217	4.226e-02	0.301	-4.020	TUBGCP3	tubulin, gamma complex associated protein 3	13	-112187328	NM_006322	10426	13q34	Hs.224152	8	structural constituent of cytoskeleton protein binding cytoplasm centriole polar microtubule microtubule microtubule nucleation gamma-tubulin binding
239100_x_at	-0.324	4.597	-2.217	4.227e-02	0.301	-4.020	PCNX	pecanex homolog (Drosophila)	14	70443874	W03928	22990	14q24.2	Hs.446559	10	membrane integral to membrane
1558537_x_at	0.291	4.908	2.217	4.230e-02	0.301	-4.020	ZNF844	zinc finger protein 844	19	12036545	AK098117	284391	19p13.2	Hs.646391	2	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
222487_s_at	-0.329	7.105	-2.216	4.231e-02	0.301	-4.021	RPS27L	ribosomal protein S27-like	15	-61232591	BC003667	51065	15q22.2	Hs.108957	6	structural constituent of ribosome intracellular nucleus ribosome DNA repair translation response to DNA damage stimulus zinc ion binding translation activator activity caspase activator activity G1 DNA damage checkpoint DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis positive regulation of anti-apoptosis metal ion binding
204524_at	-0.177	7.350	-2.216	4.232e-02	0.301	-4.021	PDPK1	3-phosphoinositide dependent protein kinase-1	16	2527970	NM_002613	5170	16p13.3	Hs.459691	103	nucleotide binding 3-phosphoinositide-dependent protein kinase activity protein binding ATP binding cytoplasm cytosol plasma membrane plasma membrane negative regulation of protein kinase activity intracellular signaling cascade transferase activity peptidyl-threonine phosphorylation actin cytoskeleton organization activation of protein kinase B activity cellular response to insulin stimulus regulation of establishment of protein localization	PPAR signaling pathway mTOR signaling pathway Focal adhesion Insulin signaling pathway Endometrial cancer Prostate cancer Non-small cell lung cancer
231166_at	-0.377	7.087	-2.216	4.233e-02	0.301	-4.021	GPR155	G protein-coupled receptor 155	2	-175004620	AI733474	151556	2q31.1	Hs.516604	9	intracellular signaling cascade membrane integral to membrane
216484_x_at	-0.179	8.173	-2.216	4.233e-02	0.301	-4.021	HDGF	hepatoma-derived growth factor (high-mobility group protein 1-like)	1	-154978522, -154978522, -154978522	L24521	3068	1q21-q23	Hs.506748	22	nucleotide binding DNA binding extracellular space nucleus cytoplasm signal transduction growth factor activity heparin binding cell proliferation regulation of transcription
229871_at	0.210	6.649	2.216	4.234e-02	0.301	-4.021	SAMD4B	sterile alpha motif domain containing 4B	19	44524947	W74622	55095	19q13.2	Hs.612332	8	protein binding
202853_s_at	-0.355	7.410	-2.216	4.235e-02	0.301	-4.021	RYK	RYK receptor-like tyrosine kinase	3	-135358667	NM_002958	6259	3q22	Hs.654562	13	nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding membrane fraction plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction axonogenesis transferase activity Wnt-protein binding Wnt receptor activity skeletal system morphogenesis
1557080_s_at	0.389	5.672	2.216	4.236e-02	0.301	-4.022	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	13	100902966	AI753143	9358	13q33	Hs.696554	5	receptor activity binding extracellular region cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex
214298_x_at	0.237	4.890	2.216	4.236e-02	0.301	-4.022	SEPT6	septin 6	X	-118634936, -118633715	AL568374	23157	Xq24	Hs.496666	22	nucleotide binding cytokinesis protein binding protein binding GTP binding cellular_component cell cycle septin complex
234873_x_at	0.186	11.469	2.216	4.236e-02	0.301	-4.022	RPL7A	ribosomal protein L7a	9	135204889	AJ224080	6130	9q34	Hs.499839	31	RNA binding structural constituent of ribosome membrane fraction cytosol translational elongation cytosolic large ribosomal subunit ribosome biogenesis polysomal ribosome	Ribosome
239417_x_at	0.215	5.264	2.216	4.238e-02	0.301	-4.022	C6orf52	chromosome 6 open reading frame 52	6	-10779638, -10779638	AW103116	347744	6p24.1	Hs.61389	1
1554660_a_at	-0.387	3.918	-2.215	4.238e-02	0.301	-4.022	C1orf71	chromosome 1 open reading frame 71	1	244796261, 244796261	BC036200	163882	1q44	Hs.368353	9	membrane integral to membrane protein complex
1560078_at	-0.208	4.273	-2.215	4.239e-02	0.301	-4.022	LAMA3	laminin, alpha 3	18	19523559, 19706981	AL708055	3909	18q11.2	Hs.436367	49	receptor binding structural molecule activity extracellular region basement membrane laminin-1 complex epidermis development regulation of cell adhesion regulation of cell migration regulation of embryonic development	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
212119_at	-0.213	10.984	-2.215	4.239e-02	0.301	-4.022	RHOQ	ras homolog gene family, member Q	2	46623370	BF670447	23433	2p21	Hs.709193	27	nucleotide binding GTPase activity profilin binding GTP binding intracellular cytoplasm actin filament plasma membrane GTP catabolic process small GTPase mediated signal transduction insulin receptor signaling pathway regulation of cell shape positive regulation of specific transcription from RNA polymerase II promoter cortical actin cytoskeleton organization GBD domain binding regulation of actin cytoskeleton organization membrane raft positive regulation of glucose import positive regulation of filopodium assembly regulation of establishment of protein localization	Insulin signaling pathway
211062_s_at	0.155	6.147	2.215	4.239e-02	0.301	-4.022	CPZ	carboxypeptidase Z	4	8645334	BC006393	8532	4p16.1	Hs.78068	8	metallocarboxypeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity metallopeptidase activity zinc ion binding Wnt receptor signaling pathway metal ion binding
203882_at	0.344	7.118	2.215	4.240e-02	0.301	-4.023	IRF9	interferon regulatory factor 9	14	23700261	NM_006084	10379	14q11.2	Hs.1706	33	transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter cell surface receptor linked signal transduction response to virus identical protein binding type I interferon biosynthetic process	Jak-STAT signaling pathway
228314_at	0.390	6.106	2.215	4.240e-02	0.301	-4.023	LRRC8C	leucine rich repeat containing 8 family, member C	1	89871231	BE877357	84230	1p22.2	Hs.412836	6	protein binding membrane integral to membrane
216331_at	-0.210	9.969	-2.215	4.240e-02	0.301	-4.023	ITGA7	integrin, alpha 7	12	-54364622, -54364622	AK022548	3679	12q13	Hs.524484	36	receptor activity calcium ion binding protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway muscle organ development integrin complex regulation of cell shape membrane integral to membrane blood vessel morphogenesis	Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
213733_at	0.208	4.788	2.215	4.240e-02	0.301	-4.023	MYO1F	myosin IF	19	-8491996	BF740152	4542	19p13.3-p13.2	Hs.465818	11	nucleotide binding motor activity actin binding calmodulin binding ATP binding negative regulation of cell adhesion biological_process unconventional myosin complex positive regulation of cell migration cortical actin cytoskeleton filamentous actin regulation of actin cytoskeleton organization neutrophil degranulation regulation of innate immune response defense response to Gram-positive bacterium
1553893_at	0.235	5.005	2.215	4.241e-02	0.301	-4.023	CCDC105	coiled-coil domain containing 105	19	14982538	NM_173482	126402	19p13.12	Hs.375985	2
231389_at	-0.267	4.319	-2.215	4.241e-02	0.301	-4.023	CXorf41	chromosome X open reading frame 41	X	106336517	AL136112	139212	Xq22.3	Hs.128836	4
226698_at	0.164	5.393	2.215	4.242e-02	0.301	-4.023	FCHSD1	FCH and double SH3 domains 1	5	-140999052	BE646638	89848	5q31.3	Hs.591257	8
214672_at	0.308	5.713	2.215	4.245e-02	0.301	-4.024	TTLL5	tubulin tyrosine ligase-like family, member 5	14	75197373	AB023215	23093	14q24.3	Hs.709609	7	tubulin-tyrosine ligase activity nucleus cytoplasm cilium microtubule basal body transcription protein modification process ligase activity
219305_x_at	0.220	5.808	2.215	4.246e-02	0.301	-4.024	FBXO2	F-box protein 2	1	-11631034	NM_012168	26232	1p36.22	Hs.132753 Hs.556006	9	glycoprotein binding ubiquitin-protein ligase activity protein modification process proteolysis ubiquitin-dependent protein catabolic process glycoprotein catabolic process carbohydrate binding ER-associated protein catabolic process regulation of protein ubiquitination dendritic spine	Ubiquitin mediated proteolysis
1565681_s_at	-0.364	6.440	-2.214	4.247e-02	0.301	-4.024	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	10	-310131	N42910	22982	10p15.3	Hs.432397	7	catalytic activity nucleus transcription factor binding metabolic process
203837_at	0.528	6.437	2.214	4.250e-02	0.301	-4.025	MAP3K5	mitogen-activated protein kinase kinase kinase 5	6	-136919879	NM_005923	4217	6q22.33	Hs.186486	108	MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding protein amino acid phosphorylation apoptosis activation of JUN kinase activity induction of apoptosis by extracellular signals caspase activator activity transferase activity protein homodimerization activity interspecies interaction between organisms	MAPK signaling pathway Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS)
244819_x_at	0.341	2.677	2.214	4.252e-02	0.301	-4.025	PSPH	phosphoserine phosphatase	7	-56046237	AI936197	5723	7p15.2-p15.1	Hs.512656	20	magnesium ion binding phosphoserine phosphatase activity protein binding L-serine biosynthetic process metabolic process cellular amino acid biosynthetic process hydrolase activity	Glycine, serine and threonine metabolism Metabolic pathways
217803_at	-0.439	7.676	-2.214	4.253e-02	0.301	-4.025	GOLPH3	golgi phosphoprotein 3 (coat-protein)	5	-32160580	NM_022130	64083	5p13.3	Hs.408909	6	protein binding cytoplasm mitochondrion Golgi apparatus trans-Golgi network membrane positive regulation of TOR signaling pathway
203886_s_at	0.307	7.015	2.213	4.257e-02	0.302	-4.026	FBLN2	fibulin 2	3	13565624	NM_001998	2199	3p25.1	Hs.198862	23	extracellular matrix structural constituent calcium ion binding extracellular region proteinaceous extracellular matrix
206933_s_at	0.204	4.844	2.213	4.259e-02	0.302	-4.026	H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	1	9217449	NM_004285	9563	1p36	Hs.463511	25	glucose-6-phosphate dehydrogenase activity binding endoplasmic reticulum endoplasmic reticulum lumen microsome carbohydrate metabolic process glucose metabolic process pentose-phosphate shunt oxidoreductase activity hydrolase activity 6-phosphogluconolactonase activity glucose 1-dehydrogenase activity oxidation reduction	Pentose phosphate pathway Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways
221952_x_at	0.265	9.485	2.212	4.263e-02	0.302	-4.027	TRMT5	TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)	14	-60507919	AB037814	57570	14q23.1	Hs.380159	5	cytoplasm tRNA processing methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity transferase activity
201779_s_at	-0.321	9.059	-2.212	4.264e-02	0.302	-4.027	RNF13	ring finger protein 13	3	151013164	AF070558	11342	3q25.1	Hs.12333 Hs.712766	10	protein binding nucleus cytoplasm zinc ion binding metal ion binding
220984_s_at	0.203	5.658	2.212	4.264e-02	0.302	-4.027	SLCO5A1	solute carrier organic anion transporter family, member 5A1	8	-70747123, -70747123, -70747123	NM_030958	81796	8q13.3	Hs.152460 Hs.443609	3	transporter activity transport membrane integral to membrane
220744_s_at	0.200	5.555	2.212	4.264e-02	0.302	-4.028	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)	3	130641657, 130641657	NM_018262	55764	3q21	Hs.655284	6	cytoplasm
211983_x_at	0.408	10.704	2.212	4.265e-02	0.302	-4.028	ACTG1	actin, gamma 1	17	-77091593	BE741683	71	17q25	Hs.514581	102	nucleotide binding structural constituent of cytoskeleton ATP binding cytoplasm cytoskeleton cell motion identical protein binding response to calcium ion	Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton Vibrio cholerae infection Pathogenic Escherichia coli infection - EHEC Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
241601_at	-0.323	5.930	-2.212	4.266e-02	0.302	-4.028	WIPF3	WAS/WASL interacting protein family, member 3	7	29840865	H58488	644150	7p14.3	Hs.709280	5	actin binding cytoplasm multicellular organismal development spermatogenesis cell differentiation
225489_at	-0.387	7.352	-2.212	4.266e-02	0.302	-4.028	TMEM18	transmembrane protein 18	2	-657972	AI720705	129787	2p25.3	Hs.43899	6	membrane integral to membrane
239385_at	0.169	2.711	2.212	4.267e-02	0.302	-4.028	TFG	TRK-fused gene	3	101910849	AI150613	10342	3q12.2	Hs.518123	25	signal transducer activity cytoplasm identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade	Pathways in cancer Thyroid cancer
222831_at	0.404	5.773	2.212	4.269e-02	0.302	-4.029	SAP30L	SAP30-like	5	153805709	NM_024632	79685	5q33.2	Hs.592566	8	nucleus nucleolus regulation of transcription
216916_s_at	0.204	4.943	2.212	4.270e-02	0.302	-4.029	DLGAP2	discs, large (Drosophila) homolog-associated protein 2	8	1436975	AF009204	9228	8p23	Hs.113287	15	protein binding neurofilament plasma membrane cell-cell signaling nerve-nerve synaptic transmission postsynaptic density cell junction synapse postsynaptic membrane
204900_x_at	-0.310	6.001	-2.211	4.272e-02	0.302	-4.029	SAP30	Sin3A-associated protein, 30kDa	4	174528667	NM_003864	8819	4q34.1	Hs.591715	30	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding nucleus regulation of transcription
200787_s_at	0.344	5.202	2.211	4.273e-02	0.302	-4.029	PEA15	phosphoprotein enriched in astrocytes 15	1	158441748	BC002426	8682	1q21.1	Hs.517216	37	protein binding cytoplasm microtubule associated complex anti-apoptosis carbohydrate transport regulation of apoptosis negative regulation of glucose import
205738_s_at	0.687	11.432	2.211	4.273e-02	0.302	-4.029	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)	1	-31610686	NM_004102	2170	1p33-p32	Hs.657242	35	transporter activity cytoplasm phosphatidylcholine biosynthetic process transport negative regulation of cell proliferation lipid binding	PPAR signaling pathway
200000_s_at	-0.230	8.398	-2.211	4.273e-02	0.302	-4.029	PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	17	-1500672	NM_006445	10594	17p13.3	Hs.181368	42	nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex U5 snRNP visual perception RNA splicing nuclear speck RNA splicing factor activity, transesterification mechanism response to stimulus
232968_at	0.168	3.638	2.211	4.274e-02	0.302	-4.030	FANK1	fibronectin type III and ankyrin repeat domains 1	10	127575097	AU143929	92565	10q26.2	Hs.352591	7	nucleus cytoplasm
243832_at	-0.182	2.818	-2.211	4.275e-02	0.302	-4.030	WDR33	WD repeat domain 33	2	-128238511, -128209431, -128178277	AV706184	55339	2q14.3	Hs.620490	10	molecular_function protein binding nucleus postreplication repair spermatogenesis
205239_at	-0.360	2.437	-2.211	4.275e-02	0.302	-4.030	AREG	amphiregulin	4	75529716, 75699652	NM_001657	374	4q13-q21	Hs.270833	61	cytokine activity extracellular space epidermal growth factor receptor signaling pathway G-protein coupled receptor protein signaling pathway cell-cell signaling growth factor activity cell proliferation cell surface membrane integral to membrane positive regulation of DNA replication	ErbB signaling pathway
213666_at	0.259	4.713	2.211	4.278e-02	0.302	-4.030	SEPT6	septin 6	X	-118634936, -118633715	AK026589	23157	Xq24	Hs.496666	22	nucleotide binding cytokinesis protein binding protein binding GTP binding cellular_component cell cycle septin complex
217911_s_at	-0.226	10.389	-2.211	4.278e-02	0.302	-4.030	BAG3	BCL2-associated athanogene 3	10	121400871	NM_004281	9531	10q25.2-q26.2	Hs.523309	37	protein binding cellular_component cytosol protein folding anti-apoptosis
204830_x_at	0.264	4.280	2.210	4.280e-02	0.302	-4.031	PSG5	pregnancy specific beta-1-glycoprotein 5	19	-48363734	NM_002781	5673	19q13.2	Hs.654415	15	extracellular region female pregnancy
228916_at	-0.234	5.445	-2.210	4.280e-02	0.302	-4.031	CWF19L2	CWF19-like 2, cell cycle control (S. pombe)	11	-106702281	BE857467	143884	11q22.3	Hs.212140	4
1558028_x_at	-0.633	5.884	-2.210	4.282e-02	0.302	-4.031	LOC647979	hypothetical LOC647979	20	-34096955	BI857154	647979	20q11.23	Hs.649310 Hs.718413	2
224436_s_at	0.519	7.121	2.210	4.283e-02	0.302	-4.032	NIPSNAP3A	nipsnap homolog 3A (C. elegans)	9	106549789	BC005935	25934	9q31.1	Hs.530275	6	cytoplasm cytosol
1552684_a_at	-0.288	5.289	-2.210	4.284e-02	0.302	-4.032	SENP8	SUMO/sentrin specific peptidase family member 8	15	70197807	NM_145204	123228	15q23	Hs.513002	9	protein binding proteolysis peptidase activity cysteine-type peptidase activity modification-dependent protein catabolic process
209255_at	-1.088	6.625	-2.210	4.284e-02	0.302	-4.032	KLHDC10	kelch domain containing 10	7	129497584	D87454	23008	7q32.2	Hs.520710	3
202746_at	0.336	8.510	2.210	4.284e-02	0.302	-4.032	ITM2A	integral membrane protein 2A	X	-78502536	AL021786	9452	Xq13.3-Xq21.2	Hs.17109 Hs.694944	14	cytoplasm plasma membrane integral to membrane
212365_at	0.328	6.043	2.210	4.285e-02	0.302	-4.032	MYO1B	myosin IB	2	191818351, 191818498	BF215996	4430	2q12-q34	Hs.439620	12	nucleotide binding motor activity actin binding calmodulin binding ATP binding myosin complex
231595_at	0.200	5.832	2.210	4.287e-02	0.302	-4.032	LOC100129827	hypothetical protein LOC100129827	11		AI075905	100129827	11p15.4	Hs.246769	1
216125_s_at	-0.545	5.549	-2.209	4.288e-02	0.302	-4.032	RANBP9	RAN binding protein 9	6	-13729708	AF064606	10048	6p23	Hs.708182	37	nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding
1559517_a_at	0.194	3.243	2.209	4.289e-02	0.302	-4.033	SPIRE1	spire homolog 1 (Drosophila)	18	-12436510, -12436510	AL833817	56907	18p11.21	Hs.515283	8	actin binding protein binding cytoplasm cytoskeleton transport perinuclear region of cytoplasm	Dorso-ventral axis formation
221632_s_at	-0.276	5.614	-2.209	4.289e-02	0.302	-4.033	WDR4	WD repeat domain 4	21	-43142404, -43136272	BC001074	10785	21q22.3	Hs.248815	10	protein binding nucleus nucleoplasm cytoplasm tRNA modification tRNA (guanine-N7-)-methyltransferase activity
214152_at	-0.268	7.299	-2.209	4.290e-02	0.302	-4.033	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AU144243	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
203073_at	-0.428	6.727	-2.209	4.294e-02	0.303	-4.034	COG2	component of oligomeric golgi complex 2	1	228844824	NM_007357	22796	1q42.2	Hs.211800	12	Golgi membrane protein binding Golgi apparatus Golgi stack protein amino acid glycosylation intracellular protein transport intra-Golgi vesicle-mediated transport Golgi organization protein transporter activity oligosaccharide biosynthetic process membrane Golgi transport complex Golgi transport complex
230531_at	0.274	5.158	2.209	4.294e-02	0.303	-4.034	KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	19	-55510576	AI796491	3748	19q13.3-q13.4	Hs.467146	9	voltage-gated ion channel activity voltage-gated potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex cell death membrane integral to membrane potassium ion binding
229999_at	-0.374	5.951	-2.209	4.294e-02	0.303	-4.034	LOC100128416	RAB28, member RAS oncogene family pseudogene	X		AI080106	100128416	Xq26.3	Hs.432355 Hs.709312	1
206741_at	0.251	4.006	2.208	4.298e-02	0.303	-4.035	C3orf32	chromosome 3 open reading frame 32	3	-8636319	NM_015931	51066	3p26.1	Hs.561182	4
219687_at	0.204	2.742	2.208	4.299e-02	0.303	-4.035	HHAT	hedgehog acyltransferase	1	208568228, 208568886	NM_018194	55733	1q32	Hs.58650	8	nucleotide binding GTP binding endoplasmic reticulum multicellular organismal development acyltransferase activity membrane integral to membrane transferase activity
211609_x_at	-0.281	10.078	-2.208	4.299e-02	0.303	-4.035	PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1	149493820	U51007	5710	1q21.3	Hs.505059	62	proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
212692_s_at	0.380	6.979	2.208	4.302e-02	0.303	-4.035	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	4	-151405045	W60686	987	4q31.3	Hs.480938	9	protein binding cellular_component biological_process
203820_s_at	-0.316	3.424	-2.208	4.303e-02	0.303	-4.035	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	7	-23316352	NM_006547	10643	7p11	Hs.700696	37	nucleotide binding RNA binding nucleus cytoplasm anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process translation regulator activity mRNA 5'-UTR binding
208370_s_at	-0.434	7.490	-2.207	4.304e-02	0.303	-4.036	RCAN1	regulator of calcineurin 1	21	-34810653, -34810653, -34810653	NM_004414	1827	21q22.1-q22.2 21q22.12	Hs.282326	45	transcription factor activity protein binding nucleus cytoplasm signal transduction central nervous system development blood circulation response to mechanical stimulus calcium-mediated signaling response to estrogen stimulus regulation of phosphoprotein phosphatase activity skeletal muscle fiber development negative regulation of smooth muscle cell differentiation
218045_x_at	0.220	5.503	2.207	4.306e-02	0.303	-4.036	PTMS	parathymosin	12	6745801	NM_002824	5763	12p13	Hs.504613	12	nucleus DNA replication immune response
244074_at	0.325	4.230	2.207	4.310e-02	0.303	-4.037	LOC100129104	similar to hydroxyproline-rich glycoprotein VSP-3	8		AL575511	100129104	8q24.22	Hs.598335 Hs.710138
1560458_s_at	-0.195	2.194	-2.207	4.311e-02	0.303	-4.037	CAPS2	calcyphosine 2	12	-73956025	BC033860	84698	12q21.1-q21.2	Hs.407154	6	calcium ion binding
225003_at	-0.250	8.568	-2.207	4.312e-02	0.303	-4.037	TMEM205	transmembrane protein 205	19	-11314451	BF343862	374882	19p13.2	Hs.8036	2	membrane integral to membrane
242210_at	-0.245	4.497	-2.206	4.313e-02	0.303	-4.037	ZNF24	zinc finger protein 24	18	-31166175	AA749167	7572	18q12	Hs.514802	15	transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding negative regulation of transcription transcription repressor activity metal ion binding
213821_s_at	0.292	5.211	2.206	4.313e-02	0.303	-4.038	IDS	iduronate 2-sulfatase	X	-148376566, -148368202	AI819115	3423	Xq28	Hs.460960	73	iduronate-2-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
214992_s_at	-0.349	5.483	-2.206	4.313e-02	0.303	-4.038	DNASE2	deoxyribonuclease II, lysosomal	19	-12847024	AD000092	1777	19p13.2	Hs.118243	27	DNA binding endodeoxyribonuclease activity deoxyribonuclease II activity protein binding lysosome DNA catabolic process apoptosis multicellular organismal development hydrolase activity erythrocyte differentiation	Lysosome
225252_at	0.309	6.959	2.206	4.315e-02	0.303	-4.038	SRXN1	sulfiredoxin 1 homolog (S. cerevisiae)	20	-575267	AL121758	140809	20p13	Hs.355284 Hs.516830	18	nucleotide binding magnesium ion binding ATP binding cytoplasm cytosol response to oxidative stress antioxidant activity sulfiredoxin activity oxidation reduction
222130_s_at	-0.275	6.905	-2.206	4.316e-02	0.303	-4.038	FTSJ2	FtsJ homolog 2 (E. coli)	7	-2240451	AK024635	29960	7p22	Hs.279877	4	nucleic acid binding nucleus nucleolus rRNA processing RNA methyltransferase activity transferase activity rRNA methylation methylation
1559481_at	0.161	3.369	2.206	4.318e-02	0.303	-4.039	CHIC1	cysteine-rich hydrophobic domain 1	X	72699708	AL832095	53344	Xq13-q21	Hs.496323	5	plasma membrane cytoplasmic vesicle
236271_at	0.221	5.109	2.206	4.318e-02	0.303	-4.039	LOC100131721	hypothetical protein LOC100131721	8		AA913233	100131721	8q21.13
216481_at	-0.247	7.324	-2.206	4.319e-02	0.303	-4.039	GRIP2	glutamate receptor interacting protein 2	3	-14510176	AF052177	80852	3p24-p23	Hs.517819	12	protein binding cytoplasm membrane
209791_at	0.412	10.070	2.205	4.322e-02	0.303	-4.039	PADI2	peptidyl arginine deiminase, type II	1	-17265842	AL049569	11240	1p36.13	Hs.33455	20	protein-arginine deiminase activity calcium ion binding cytoplasm protein modification process hydrolase activity peptidyl-citrulline biosynthetic process from peptidyl-arginine
222336_at	-0.267	3.118	-2.205	4.322e-02	0.303	-4.039	C4orf34	chromosome 4 open reading frame 34	4	-39228940	AW974915	201895	4p14	Hs.576320	4	protein binding membrane integral to membrane
205628_at	-0.202	3.465	-2.205	4.323e-02	0.304	-4.040	PRIM2	primase, DNA, polypeptide 2 (58kDa)	6	57290380	NM_000947	5558	6p12-p11.1	Hs.654580	16	DNA binding DNA primase activity iron ion binding nucleoplasm alpha DNA polymerase:primase complex DNA replication DNA replication, synthesis of RNA primer transcription transferase activity nucleotidyltransferase activity metal ion binding 4 iron, 4 sulfur cluster binding	Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication
204391_x_at	-0.300	6.725	-2.205	4.324e-02	0.304	-4.040	TRIM24	tripartite motif-containing 24	7	137795618	NM_015905	8805	7q32-q34	Hs.490287	25	DNA binding transcription coactivator activity receptor binding intracellular nucleus transcription from RNA polymerase II promoter zinc ion binding regulation of transcription metal ion binding
225610_at	-0.338	7.414	-2.205	4.325e-02	0.304	-4.040	UHRF2	ubiquitin-like with PHD and ring finger domains 2	9	6403150	BF511410	115426	9p24.1	Hs.493401	10	DNA binding ubiquitin-protein ligase activity protein binding nucleus ubiquitin-dependent protein catabolic process zinc ion binding cell proliferation ligase activity cell differentiation metal ion binding regulation of cell cycle protein autoubiquitination
205022_s_at	-0.344	8.479	-2.205	4.325e-02	0.304	-4.040	FOXN3	forkhead box N3	14	-88692268, -88692268	NM_005197	1112	14q31.3	Hs.434286 Hs.621371	16	DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent
212403_at	-0.290	7.503	-2.205	4.328e-02	0.304	-4.041	UBE3B	ubiquitin protein ligase E3B	12	108399821	AI749193	89910	12q24.11	Hs.374067	8	intracellular protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
218002_s_at	0.658	8.200	2.204	4.329e-02	0.304	-4.041	CXCL14	chemokine (C-X-C motif) ligand 14	5	-134934267	NM_004887	9547	5q31	Hs.483444	32	extracellular region extracellular space Golgi apparatus chemotaxis immune response signal transduction cell-cell signaling chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
213634_s_at	0.199	6.114	2.204	4.330e-02	0.304	-4.041	TRMU	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	22	45109961	AL031588	55687	22q13	Hs.439524	13	tRNA binding nucleotide binding tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity ATP binding cytoplasm mitochondrion tRNA processing transferase activity
218515_at	-0.306	6.436	-2.204	4.332e-02	0.304	-4.041	C21orf66	chromosome 21 open reading frame 66	21	-33035520, -33028083, -33028080	NM_016631	94104	21q21.3	Hs.644004	9	transcription factor activity nucleus cytosol regulation of transcription, DNA-dependent
204277_s_at	0.233	5.173	2.204	4.333e-02	0.304	-4.042	TK2	thymidine kinase 2, mitochondrial	16	-65100845	BE895437	7084	16q22-q23.1	Hs.512619	26	nucleotide binding thymidine kinase activity ATP binding mitochondrion mitochondrial inner membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process DNA replication kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor	Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways
213194_at	-0.549	6.449	-2.204	4.334e-02	0.304	-4.042	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	3	-78729077, -78729077	BF059159	6091	3p12	Hs.13640	34	receptor activity integral to plasma membrane chemotaxis cell adhesion homophilic cell adhesion multicellular organismal development nervous system development axon guidance receptor activity cell surface membrane cell differentiation identical protein binding positive regulation of axonogenesis	Axon guidance
225409_at	-0.263	7.072	-2.203	4.338e-02	0.304	-4.043	C2orf64	chromosome 2 open reading frame 64	2	-98582296	AA115117	493753	2q11.2	Hs.596537	1
228297_at	0.457	5.949	2.203	4.342e-02	0.304	-4.043	CNN3	calponin 3, acidic	1	-95135094	AI807004	1266	1p22-p21	Hs.706617	13	actin binding calmodulin binding tropomyosin binding cellular_component smooth muscle contraction troponin C binding actomyosin structure organization
219452_at	0.182	4.806	2.203	4.342e-02	0.304	-4.043	DPEP2	dipeptidase 2	16	-66578795	NM_022355	64174	16q22.1	Hs.372633	7	proteolysis peptidase activity metalloexopeptidase activity dipeptidyl-peptidase activity zinc ion binding membrane dipeptidase activity anchored to membrane metal ion binding
201236_s_at	-0.705	8.144	-2.203	4.342e-02	0.304	-4.044	BTG2	BTG family, member 2	1	201541286	NM_006763	7832	1q32	Hs.519162	45	protein binding DNA repair protein amino acid methylation response to DNA damage stimulus negative regulation of cell proliferation anterior/posterior pattern formation neuron differentiation negative regulation of apoptosis regulation of transcription
207511_s_at	-0.255	5.553	-2.202	4.346e-02	0.304	-4.044	C2orf24	chromosome 2 open reading frame 24	2	-219744862	NM_015680	27013	2q35	Hs.4973	5	membrane integral to membrane
234440_at	0.163	3.339	2.202	4.346e-02	0.304	-4.044	TRD@	T cell receptor delta locus	14		X13954	6964	14q11.2	Hs.540121 Hs.713514 Hs.74647	30
242497_at	0.292	5.332	2.202	4.350e-02	0.305	-4.045	TRAFD1	TRAF-type zinc finger domain containing 1	12	111047731	AI694735	10906	12q	Hs.5148	10	protein binding intracellular zinc ion binding metal ion binding
213310_at	0.425	5.823	2.202	4.352e-02	0.305	-4.046	EIF2C2	eukaryotic translation initiation factor 2C, 2	8	-141610445	AI613483	27161	8q24	Hs.449415	47	RNA 7-methylguanosine cap binding cytoplasmic mRNA processing body translation initiation factor activity endonuclease activity protein binding nucleus cytoplasm mRNA cap binding complex regulation of translation RNA-induced silencing complex hydrolase activity gene silencing by RNA pre-microRNA processing micro-ribonucleoprotein complex siRNA binding gene silencing by miRNA, negative regulation of translation gene silencing by miRNA, negative regulation of translation gene silencing by miRNA, mRNA cleavage gene silencing by miRNA, mRNA cleavage regulation of transcription negative regulation of translational initiation metal ion binding endoribonuclease activity, cleaving siRNA-paired mRNA
204554_at	-0.525	6.615	-2.201	4.354e-02	0.305	-4.046	PPP1R3D	protein phosphatase 1, regulatory (inhibitor) subunit 3D	20	-57945281	AL109928	5509	20q13.3	Hs.42215	7	protein serine/threonine phosphatase activity protein binding carbohydrate metabolic process glycogen metabolic process	Insulin signaling pathway
205241_at	0.217	6.683	2.201	4.354e-02	0.305	-4.046	SCO2	SCO cytochrome oxidase deficient homolog 2 (yeast)	22	-49308862	NM_005138	9997	22q13.33	Hs.718545	25	copper ion binding mitochondrion mitochondrial inner membrane copper ion transport cellular copper ion homeostasis respiratory chain complex IV assembly cell redox homeostasis metal ion binding oxidation reduction
1554470_s_at	-0.477	6.802	-2.201	4.355e-02	0.305	-4.046	ZBTB44	zinc finger and BTB domain containing 44	11	-129601783	BC030580	29068	11q24.3	Hs.719099	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
1566524_a_at	0.192	4.829	2.201	4.356e-02	0.305	-4.046	hCG_1986447	hCG1986447	2		AL832712	729324	2p14	Hs.646781	2
215817_at	0.211	3.545	2.201	4.358e-02	0.305	-4.047	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	18	59405513	BE148534	5275	18q21.3-q22	Hs.241407	12	serine-type endopeptidase inhibitor activity cellular_component cytoplasm response to UV regulation of proteolysis peptidase inhibitor activity
233512_at	0.197	3.106	2.201	4.358e-02	0.305	-4.047	SH3RF3	SH3 domain containing ring finger 3	2	109112428	AF035291	344558	2q13	Hs.171244 Hs.535157	2	protein binding zinc ion binding metal ion binding
202127_at	-0.325	7.218	-2.201	4.359e-02	0.305	-4.047	PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	6	3966567	AB011108	8899	6p25.2	Hs.159014	20	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus spliceosomal complex chromosome mRNA processing protein amino acid phosphorylation RNA splicing transferase activity
218424_s_at	-0.215	7.754	-2.201	4.360e-02	0.305	-4.047	STEAP3	STEAP family member 3	2	119697853	NM_018234	55240	2q14.2	Hs.647822	11	binding iron ion binding copper ion binding endosome ion transport iron ion transport apoptosis cell cycle electron carrier activity membrane integral to membrane oxidoreductase activity metal ion binding FAD binding oxidation reduction	p53 signaling pathway
237691_x_at	-0.372	6.795	-2.201	4.360e-02	0.305	-4.047	ENO3	enolase 3 (beta, muscle)	17	4795130	AW138371	2027	17pter-p11	Hs.224171	11	phosphopyruvate hydratase complex magnesium ion binding phosphopyruvate hydratase activity cytoplasm glycolysis lyase activity	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways RNA degradation
209905_at	0.319	7.543	2.201	4.360e-02	0.305	-4.047	HOXA9	homeobox A9	7	-27168581	AI246769	3205	7p15-p14	Hs.659350	63	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity sequence-specific DNA binding
202046_s_at	0.157	2.928	2.200	4.363e-02	0.305	-4.048	GRLF1	glucocorticoid receptor DNA binding factor 1	19	52113772	NM_004491	2909	19q13.3	Hs.509447	26	DNA binding transcription corepressor activity GTPase activator activity intracellular nucleus cytoplasm signal transduction negative regulation of transcription	Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton
208090_s_at	-0.203	5.779	-2.200	4.363e-02	0.305	-4.048	AIRE	autoimmune regulator	21	44530190, 44534701	NM_000658	326	21q22.3	Hs.129829	80	DNA binding chromatin binding nucleus cytoplasm regulation of transcription, DNA-dependent humoral immune response zinc ion binding promoter binding transcription activator activity histone binding translation regulator activity metal ion binding	Ubiquitin mediated proteolysis Primary immunodeficiency
228727_at	-0.338	7.055	-2.200	4.366e-02	0.305	-4.048	ANXA11	annexin A11	10	-81904859	BF969970	311	10q23	Hs.530291	25	calcium ion binding calcium-dependent phospholipid binding nucleus nuclear envelope nucleoplasm cytoplasm immune response melanosome calcium-dependent protein binding
213309_at	-0.556	8.500	-2.200	4.369e-02	0.305	-4.049	PLCL2	phospholipase C-like 2	3	16901455, 16949585	AL117515	23228	3p24.3	Hs.202010	7	phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm lipid metabolic process intracellular signaling cascade
202139_at	0.284	8.167	2.200	4.369e-02	0.305	-4.049	AKR7A2	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	1	-19503048	NM_003689	8574	1p36.13	Hs.571886	14	aldehyde reductase activity mitochondrion Golgi apparatus carbohydrate metabolic process cellular aldehyde metabolic process electron carrier activity oxidoreductase activity oxidation reduction
214269_at	0.239	4.696	2.200	4.370e-02	0.305	-4.049	MFSD7	major facilitator superfamily domain containing 7	4	-665617	AK025922	84179	4p16.3	Hs.567612	5	transport membrane integral to membrane
1569448_at	-0.172	5.840	-2.200	4.370e-02	0.305	-4.049	PGM2L1	phosphoglucomutase 2-like 1	11	-73719008	BI768721	283209	11q13.4	Hs.26612	6	carbohydrate metabolic process glucose metabolic process transferase activity isomerase activity intramolecular transferase activity, phosphotransferases glucose-1,6-bisphosphate synthase activity	Starch and sucrose metabolism
213475_s_at	0.194	5.057	2.199	4.371e-02	0.305	-4.049	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	16	30391483	AC002310	3683	16p11.2	Hs.174103	120	magnesium ion binding T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell receptor activity calcium ion binding plasma membrane cell motion inflammatory response cell adhesion heterophilic cell adhesion leukocyte adhesion signal transduction integrin-mediated signaling pathway integrin complex integral to membrane cell adhesion molecule binding	Cell adhesion molecules (CAMs) Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Regulation of actin cytoskeleton
227135_at	-0.193	5.638	-2.199	4.373e-02	0.305	-4.050	NAAA	N-acylethanolamine acid amidase	4	-77053832, -77050831	AI436803	27163	4q21.1	Hs.437365	12	molecular_function cellular_component cytoplasm lysosome lipid metabolic process biological_process hydrolase activity
1559520_at	0.190	2.784	2.199	4.375e-02	0.305	-4.050	GYPA	glycophorin A (MNS blood group)	4	-145249905	AL833104	2993	4q28.2-q31.1	Hs.434973	60	membrane fraction plasma membrane integral to membrane identical protein binding	Hematopoietic cell lineage
205640_at	0.265	5.368	2.199	4.376e-02	0.305	-4.050	ALDH3B1	aldehyde dehydrogenase 3 family, member B1	11	67532623, 67534365	NM_000694	221	11q13	Hs.523841	10	3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase [NAD(P)+] activity alcohol metabolic process cellular aldehyde metabolic process lipid metabolic process oxidoreductase activity oxidation reduction	Glycolysis / Gluconeogenesis Histidine metabolism Tyrosine metabolism Phenylalanine metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
218357_s_at	0.249	10.938	2.199	4.378e-02	0.305	-4.051	TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)	11	-111461079	NM_012459	26521	11q23.1-q23.2	Hs.279915	6	protein binding mitochondrion mitochondrial inner membrane presequence translocase complex sensory perception of sound zinc ion binding protein transport membrane mitochondrial intermembrane space protein transporter complex protein import into mitochondrial inner membrane metal ion binding intracellular protein transmembrane transport
233949_s_at	0.537	8.043	2.198	4.379e-02	0.305	-4.051	MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	20	33026866	AI160292	57644	20q11.22	Hs.414122	8	nucleotide binding motor activity actin binding ATP binding striated muscle thick filament striated muscle contraction membrane myosin complex	Tight junction
236651_at	0.167	3.018	2.198	4.379e-02	0.305	-4.051	KALRN	kalirin, RhoGEF kinase	3	125296247, 125296247, 125296247, 125786195	AI125425	8997	3q21.2	Hs.8004	24	nucleotide binding magnesium ion binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity ATP binding intracellular cytoplasm protein amino acid phosphorylation intracellular signaling cascade nervous system development actin cytoskeleton vesicle-mediated transport transferase activity regulation of Rho protein signal transduction
211071_s_at	0.664	8.059	2.198	4.381e-02	0.305	-4.051	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	1	149298774	BC006471	10962	1q21	Hs.75823	9	molecular_function cellular_component
202789_at	0.207	7.184	2.198	4.382e-02	0.305	-4.052	PLCG1	phospholipase C, gamma 1	20	39199574	AL022394	5335	20q12-q13.1	Hs.268177	211	phosphoinositide phospholipase C activity receptor signaling protein activity calcium ion binding protein binding cellular_component cytoplasm cytosol plasma membrane intracellular signaling cascade phospholipid catabolic process lipid catabolic process hydrolase activity interspecies interaction between organisms	Inositol phosphate metabolism Metabolic pathways ErbB signaling pathway Calcium signaling pathway Phosphatidylinositol signaling system VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Glioma Non-small cell lung cancer
201261_x_at	0.383	5.982	2.198	4.383e-02	0.305	-4.052	BGN	biglycan	X	152413604	BC002416	633	Xq28	Hs.821	63	extracellular matrix structural constituent protein binding extracellular region proteinaceous extracellular matrix biological_process transport vesicle
234367_x_at	0.200	5.286	2.198	4.385e-02	0.306	-4.052	TMPRSS6	transmembrane protease, serine 6	22	-35791424	AL022314	164656	22q12.3	Hs.370885	16	angiogenesis serine-type endopeptidase activity plasma membrane proteolysis intracellular signaling cascade peptidase activity integral to membrane extracellular matrix organization fibrinolysis
1555233_at	0.275	4.667	2.198	4.385e-02	0.306	-4.052	RHOJ	ras homolog gene family, member J	14	62740897	BC025770	57381	14q23.2	Hs.656339	8	nucleotide binding GTPase activity protein binding GTP binding cellular_component intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape actin cytoskeleton organization
1558653_at	-0.186	3.764	-2.198	4.386e-02	0.306	-4.052	LOC339751	hypothetical protein LOC339751	2		BC040565	339751	2q31.1	Hs.623925	1
211651_s_at	0.552	5.727	2.197	4.391e-02	0.306	-4.053	LAMB1	laminin, beta 1	7	-107351481	M20206	3912	7q22	Hs.650585	47	extracellular matrix structural constituent extracellular region basal lamina laminin-1 complex laminin-2 complex laminin-2 complex cell adhesion embryo implantation enzyme binding positive regulation of cell migration neuron projection development substrate adhesion-dependent cell spreading odontogenesis laminin-8 complex laminin-8 complex laminin-10 complex perinuclear region of cytoplasm positive regulation of epithelial cell proliferation	Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer
210407_at	-0.391	5.498	-2.197	4.394e-02	0.306	-4.054	PPM1A	protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform	14	59782222, 59785718, 59785718	AF070670	5494	14q23.1	Hs.130036	28	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity cellular_component membrane fraction voltage-gated calcium channel complex protein amino acid dephosphorylation protein C-terminus binding protein serine/threonine phosphatase complex hydrolase activity manganese ion binding positive regulation of Wnt receptor signaling pathway neuron projection positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of transcription, DNA-dependent	MAPK signaling pathway
201163_s_at	0.500	9.926	2.196	4.399e-02	0.306	-4.055	IGFBP7	insulin-like growth factor binding protein 7	4	-57592000	NM_001553	3490	4q12	Hs.479808 Hs.711065	39	regulation of cell growth insulin-like growth factor binding extracellular region cell adhesion negative regulation of cell proliferation
239377_at	-0.354	7.112	-2.196	4.400e-02	0.306	-4.055	EIF1AD	eukaryotic translation initiation factor 1A domain containing	11	-65520592	T59859	84285	11q13.1	Hs.425178	4	RNA binding translation initiation factor activity nucleus translational initiation
200723_s_at	-0.243	8.059	-2.196	4.403e-02	0.306	-4.056	CAPRIN1	cell cycle associated protein 1	11	34029805, 34029805	NM_005898	4076	11p13	Hs.471818	10	protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection
200626_s_at	-0.331	8.092	-2.195	4.408e-02	0.307	-4.057	MATR3	matrin 3	5	138637690, 138657253	NM_018834	9782	5q31.2	Hs.268939	24	nucleotide binding RNA binding structural molecule activity protein binding intracellular nucleus nuclear inner membrane zinc ion binding nuclear matrix metal ion binding
209846_s_at	0.423	6.032	2.195	4.409e-02	0.307	-4.057	BTN3A2	butyrophilin, subfamily 3, member A2	6	26473376	BC002832	11118	6p22.1	Hs.376046	9	biological_process membrane integral to membrane
209698_at	0.248	6.656	2.195	4.410e-02	0.307	-4.057	CCHCR1	coiled-coil alpha-helical rod protein 1	6	-31218194, -31218194, -2561482, -2561482, -2359996, -2359996	AF216493	54535	6p21.3	Hs.485075	23	protein binding nucleus cytoplasm protein export from nucleus multicellular organismal development cell differentiation
229533_x_at	-0.409	6.203	-2.195	4.412e-02	0.307	-4.057	ZNF680	zinc finger protein 680	7	-63622468, -63617689	AI963028	340252	7q11.21	Hs.520886	5	DNA binding intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
225257_at	-0.247	6.162	-2.195	4.412e-02	0.307	-4.058	CCDC97	coiled-coil domain containing 97	19	46507933	AA534536	90324	19q13.2	Hs.437497	2
231301_at	-0.168	2.101	-2.194	4.414e-02	0.307	-4.058	NUP54	nucleoporin 54kDa	4	-77254840	BE671244	53371	4q21.1	Hs.430435	16	nucleocytoplasmic transporter activity protein binding nucleus nuclear pore nucleoplasm cytoplasm protein targeting nucleocytoplasmic transport protein transport membrane mRNA transport intracellular protein transmembrane transport
223171_at	-0.303	6.625	-2.194	4.415e-02	0.307	-4.058	DYM	dymeclin	18	-44824169	BC001252	54808	18q12-q21.1	Hs.162996	12	cytoplasm Golgi apparatus
218506_x_at	-0.301	7.007	-2.194	4.415e-02	0.307	-4.058	GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)	16	-4793204	NM_018459	84656	16p13.3	Hs.387255	3	DNA binding phosphogluconate dehydrogenase (decarboxylating) activity binding nucleus pentose-phosphate shunt metabolic process oxidoreductase activity coenzyme binding
1553553_at	-0.363	3.668	-2.194	4.418e-02	0.307	-4.059	TAS2R39	taste receptor, type 2, member 39	7	142590633	NM_176881	259285	7q34	Hs.553660	8	receptor activity G-protein coupled receptor activity signal transduction G-protein coupled receptor protein signaling pathway membrane integral to membrane response to stimulus sensory perception of taste	Taste transduction
1569699_at	0.307	4.139	2.194	4.418e-02	0.307	-4.059	AK7	adenylate kinase 7	14	95928200	BC023986	122481	14q32.2	Hs.667462	4	nucleotide binding adenylate kinase activity ATP binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process metabolic process transferase activity nucleobase, nucleoside, nucleotide kinase activity	Purine metabolism Metabolic pathways
207998_s_at	0.215	4.853	2.194	4.419e-02	0.307	-4.059	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit	3	53504070	NM_000720	776	3p14.3	Hs.476358	25	voltage-gated ion channel activity calcium ion binding voltage-gated calcium channel complex ion transport calcium ion transport dihydropyridine-sensitive calcium channel activity membrane integral to membrane	MAPK signaling pathway Calcium signaling pathway Cardiac muscle contraction Vascular smooth muscle contraction GnRH signaling pathway Type II diabetes mellitus Alzheimer's disease Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
225242_s_at	0.595	5.742	2.194	4.420e-02	0.307	-4.059	CCDC80	coiled-coil domain containing 80	3	-113806098	AW303375	151887	3q13.2	Hs.477128	10	fibronectin binding extracellular region basement membrane interstitial matrix heparin binding positive regulation of cell-substrate adhesion extracellular matrix organization intracellular membrane-bounded organelle
233294_at	-0.677	6.452	-2.193	4.421e-02	0.307	-4.059	DENND2C	DENN/MADD domain containing 2C	1	-114928718	AI214451	163259	1p13.2	Hs.654928	5
215472_at	0.252	4.130	2.193	4.422e-02	0.307	-4.059	PACRG	PARK2 co-regulated	6	163068153, 163068991	AI017119	135138	6q26	Hs.25791	20
1552309_a_at	-0.257	12.027	-2.193	4.425e-02	0.307	-4.060	NEXN	nexilin (F actin binding protein)	1	78126787	NM_144573	91624	1p31.1	Hs.612385	6	cytoplasm cytoskeleton cell-substrate adherens junction cell junction regulation of cell migration actin filament binding regulation of cytoskeleton organization
204632_at	0.178	6.596	2.193	4.427e-02	0.307	-4.061	RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	11	63883200	NM_003942	8986	11q11-q13	Hs.105584	16	nucleotide binding magnesium ion binding ribosomal protein S6 kinase activity protein binding ATP binding ATP binding nucleus nucleus regulation of transcription, DNA-dependent protein amino acid phosphorylation protein amino acid phosphorylation protein kinase cascade transferase activity mitogen-activated protein kinase p38 binding mitogen-activated protein kinase p38 binding	MAPK signaling pathway Neurotrophin signaling pathway
231816_s_at	0.212	4.612	2.193	4.427e-02	0.307	-4.061	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	1	-152787674	AI986085	55585	1q21.3	Hs.607928	7	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
202879_s_at	0.185	5.344	2.193	4.427e-02	0.307	-4.061	CYTH1	cytohesin 1	17	-74181724	AI798823	9267	17q25	Hs.191215	28	ARF guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm plasma membrane vesicle-mediated transport regulation of cell adhesion regulation of ARF protein signal transduction
218040_at	-0.281	5.961	-2.193	4.428e-02	0.307	-4.061	PRPF38B	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	1	109036454	NM_018061	55119	1p13.3	Hs.342307	7	nucleus spliceosomal complex mRNA processing RNA splicing
220086_at	-0.279	5.762	-2.192	4.429e-02	0.307	-4.061	IKZF5	IKAROS family zinc finger 5 (Pegasus)	10	-124743186	NM_022466	64376	10q26	Hs.501289	7	DNA binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding
239897_at	-0.203	5.822	-2.192	4.431e-02	0.307	-4.061	BCLAF1	BCL2-associated transcription factor 1	6	-136619693	AW152620	9774	6q22-q23	Hs.486542	16	DNA binding protein binding nucleus cytoplasm induction of apoptosis negative regulation of transcription transcription repressor activity
229837_s_at	0.241	5.155	2.192	4.431e-02	0.307	-4.061	PRO0461	hypothetical LOC652276	16	2593385	AA534630	652276	16p13.3	Hs.459691 Hs.61960	4
235783_at	0.342	5.944	2.192	4.432e-02	0.307	-4.061	MRTO4	mRNA turnover 4 homolog (S. cerevisiae)	1	19450661	BG107419	51154	1p36.13	Hs.463797	7	intracellular nucleus nucleolus ribosome biogenesis
224856_at	-0.716	8.312	-2.192	4.432e-02	0.307	-4.062	FKBP5	FK506 binding protein 5	6	-35656311, -35649339, -35649339, -35649339	W86302	2289	6p21.3-p21.2	Hs.407190	50	peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding
215873_x_at	-0.183	5.709	-2.192	4.433e-02	0.307	-4.062	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	6	43507466	AK024446	89845	6p21.1	Hs.55879	12	nucleotide binding ATP binding plasma membrane transport integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters
1554060_s_at	0.205	2.858	2.192	4.434e-02	0.307	-4.062	SETMAR	SET domain and mariner transposase fusion gene	3	4319987, 4320296	BC011635	6419	3p26.1	Hs.475300	17	DNA binding transposase activity cellular_component nucleus DNA repair transposition, DNA-mediated response to DNA damage stimulus methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity	Lysine degradation
1564164_at	-0.355	3.321	-2.192	4.434e-02	0.307	-4.062	DENND1B	DENN/MADD domain containing 1B	1	-195788007, -195746131	AL831839	163486	1q31.3	Hs.657779	4
1556277_a_at	-0.460	5.363	-2.192	4.436e-02	0.307	-4.062	PAPD4	PAP associated domain containing 4	5	78943998	BG542611	167153	5q14.1	Hs.418198	5	nucleotide binding polynucleotide adenylyltransferase activity ATP binding nucleus cytoplasm mRNA processing transferase activity nuclear RNA-directed RNA polymerase complex RNA polyadenylation
203193_at	0.210	7.521	2.191	4.441e-02	0.308	-4.063	ESRRA	estrogen-related receptor alpha	11	63829619	NM_004451	2101	11q13	Hs.110849	59	transcription factor activity steroid hormone receptor activity steroid binding nucleus regulation of transcription, DNA-dependent zinc ion binding protein domain specific binding sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter metal ion binding
205158_at	0.378	5.675	2.191	4.442e-02	0.308	-4.063	RNASE4	ribonuclease, RNase A family, 4	14	20222211, 20226771	NM_002937	6038	14q11.1	Hs.283749	10	nucleic acid binding endonuclease activity pancreatic ribonuclease activity extracellular region mRNA cleavage hydrolase activity
218937_at	0.258	5.265	2.191	4.443e-02	0.308	-4.064	ZNF434	zinc finger protein 434	16	-3372085	NM_017810	54925	16p13.3	Hs.592078	3	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
214285_at	0.667	9.920	2.191	4.443e-02	0.308	-4.064	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)	1	-31610686	AI041520	2170	1p33-p32	Hs.657242	35	transporter activity cytoplasm phosphatidylcholine biosynthetic process transport negative regulation of cell proliferation lipid binding	PPAR signaling pathway
212281_s_at	-0.424	6.535	-2.191	4.443e-02	0.308	-4.064	TMEM97	transmembrane protein 97	17	23670247	BF038366	27346	17q11.2	Hs.199695	8	regulation of cell growth molecular_function cellular_component membrane integral to membrane
1556827_at	0.242	2.887	2.191	4.444e-02	0.308	-4.064	LOC339929	hypothetical protein LOC339929	3		BC042414	339929	3q27.3	Hs.596639	1
223635_s_at	0.240	5.460	2.191	4.444e-02	0.308	-4.064	SSBP3	single stranded DNA binding protein 3	1	-54464782, -54464782	BC003605	23648	1p32.3	Hs.658676	10	DNA binding single-stranded DNA binding nucleus transcription regulator activity regulation of transcription
239996_x_at	0.225	6.126	2.191	4.446e-02	0.308	-4.064	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	12	109203414, 109203414	AI671237	488	12q23-q24.1	Hs.506759	84	nucleotide binding magnesium ion binding regulation of the force of heart contraction calcium-transporting ATPase activity calcium ion binding ATP binding membrane fraction microsome integral to plasma membrane ATP biosynthetic process cation transport cellular calcium ion homeostasis ER-nuclear signaling pathway cell adhesion metabolic process epidermis development membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances sarcoplasmic reticulum membrane negative regulation of heart contraction S100 alpha binding sarcoplasmic reticulum calcium ion transport	Calcium signaling pathway Cardiac muscle contraction Alzheimer's disease Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
214960_at	-0.270	5.476	-2.190	4.447e-02	0.308	-4.064	API5	apoptosis inhibitor 5	11	43290080	AF229253	8539	11p11.2	Hs.435771	15	binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding
207043_s_at	-0.167	4.056	-2.190	4.451e-02	0.308	-4.065	SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	1	-44234741, -44234741	NM_006934	6536	1p33	Hs.442590	21	neurotransmitter:sodium symporter activity membrane fraction integral to plasma membrane neurotransmitter transport amino acid transport symporter activity glycine:sodium symporter activity membrane
1562972_at	-0.219	3.862	-2.190	4.452e-02	0.308	-4.065	LOC503519	hypothetical LOC503519	15		BC038777	503519	15q11.2	Hs.371380	1
204513_s_at	0.216	5.170	2.190	4.454e-02	0.308	-4.066	ELMO1	engulfment and cell motility 1	7	-36860485, -36860485, -36860485	NM_014800	9844	7p14.2-p14.1	Hs.656638	29	protein binding cytoplasm cytosol cytoskeleton plasma membrane phagocytosis, engulfment apoptosis cell motion Rac protein signal transduction SH3 domain binding actin cytoskeleton organization	Chemokine signaling pathway
232897_at	0.345	5.847	2.189	4.455e-02	0.308	-4.066	FLJ20444	hypothetical protein FLJ20444	9		AK000451	403323	9q21	Hs.536967
221225_at	0.188	5.334	2.189	4.458e-02	0.308	-4.067	DCAKD	dephospho-CoA kinase domain containing	17	-40456231, -40456231	NM_024819	79877	17q21.31	Hs.463148	1	nucleotide binding ATP binding
243564_at	0.212	3.733	2.189	4.458e-02	0.308	-4.067	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	7	-31795771	BE784669	5137	7p14.3	Hs.655694	10	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity	Purine metabolism Calcium signaling pathway Olfactory transduction
238020_at	-0.323	6.911	-2.189	4.459e-02	0.308	-4.067	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	7	102775324	BG166796	5701	7q22.1-q22.3	Hs.437366	56	nucleotide binding proteasome complex protein binding ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
221805_at	0.154	2.231	2.189	4.459e-02	0.308	-4.067	NEFL	neurofilament, light polypeptide	8	-24864387	AL537457	4747	8p21	Hs.521461	57	structural constituent of cytoskeleton neurofilament protein C-terminus binding anterograde axon cargo transport retrograde axon cargo transport axon transport of mitochondrion axon TSC1-TSC2 complex neurofilament bundle assembly neurofilament bundle assembly identical protein binding intermediate filament organization	Amyotrophic lateral sclerosis (ALS)
205773_at	-0.450	8.500	-2.189	4.460e-02	0.308	-4.067	CPEB3	cytoplasmic polyadenylation element binding protein 3	10	-93798378	NM_014912	22849	10q23.32	Hs.131683	7	nucleotide binding RNA binding
213376_at	-0.297	6.831	-2.189	4.463e-02	0.308	-4.068	ZBTB1	zinc finger and BTB domain containing 1	14	64041044, 64041044	AI656706	22890	14q23.3	Hs.655536	6	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
217069_at	0.320	4.692	2.188	4.463e-02	0.308	-4.068	MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	19	40900760	AF105279	9757	19q13.1	Hs.676457 Hs.92236	15	transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent methyltransferase activity zinc ion binding chromatin modification transferase activity histone methyltransferase complex histone methyltransferase activity (H3-K4 specific) metal ion binding chromatin-mediated maintenance of transcription
202137_s_at	-0.487	6.285	-2.188	4.464e-02	0.308	-4.068	ZMYND11	zinc finger, MYND domain containing 11	10	170423, 170423	NM_006624	10771	10p14	Hs.292265	17	negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding nucleus cell cycle zinc ion binding cell proliferation regulation of transcription metal ion binding
212581_x_at	-0.166	13.775	-2.188	4.464e-02	0.308	-4.068	GAPDH	glyceraldehyde-3-phosphate dehydrogenase	12	6513917	BE561479	2597	12p13	Hs.544577 Hs.592355 Hs.598320	130	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity protein binding cytoplasm glucose metabolic process glycolysis membrane oxidoreductase activity perinuclear region of cytoplasm NAD or NADH binding oxidation reduction	Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Alzheimer's disease
244123_at	0.187	4.965	2.188	4.467e-02	0.308	-4.068	LOC388553	similar to hCG1645909	19		BF476558	388553	19q13.32
219799_s_at	0.243	4.808	2.188	4.468e-02	0.308	-4.069	DHRS9	dehydrogenase/reductase (SDR family) member 9	2	169629544, 169631790, 169637330, 169645862	NM_005771	10170	2q31.1	Hs.179608	11	alcohol dehydrogenase (NAD) activity alcohol dehydrogenase (NAD) activity retinol dehydrogenase activity retinol dehydrogenase activity binding endoplasmic reticulum endoplasmic reticulum membrane microsome microsome androgen metabolic process membrane oxidoreductase activity racemase and epimerase activity integral to endoplasmic reticulum membrane integral to endoplasmic reticulum membrane epithelial cell differentiation progesterone metabolic process retinol metabolic process 9-cis-retinoic acid biosynthetic process 9-cis-retinoic acid biosynthetic process 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity oxidation reduction	Retinol metabolism Metabolic pathways
220918_at	0.625	5.060	2.188	4.469e-02	0.308	-4.069	C21orf96	chromosome 21 open reading frame 96	21	-35332104	NM_025143	80215	21q22.12	Hs.672131	4	cytosol
1554671_a_at	0.241	5.408	2.188	4.470e-02	0.309	-4.069	SRRM2	serine/arginine repetitive matrix 2	16	2742330	BC041155	23524	16p13.3	Hs.433343 Hs.719123	20	RNA binding protein binding nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck
1558212_at	0.381	5.993	2.187	4.473e-02	0.309	-4.070	FLJ35024	hypothetical LOC401491	9	-2525654	BC004474	401491	9p24.2	Hs.416043	2
208902_s_at	0.179	6.333	2.187	4.473e-02	0.309	-4.070	RPS28	ribosomal protein S28	19	8292383	BF431363	6234	19p13.2	Hs.153177 Hs.719103	15	structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit ribosomal small subunit biogenesis	Ribosome
238697_at	0.243	3.047	2.187	4.474e-02	0.309	-4.070	NCRNA00086	non-protein coding RNA 86	X	134383533	AA565509	399668	Xq26.3	Hs.374414	3
228418_at	-0.273	4.605	-2.187	4.475e-02	0.309	-4.070	EXOC5	exocyst complex component 5	14	-56738946	BF509391	10640	14q22.3	Hs.715522	15	cytoplasm exocytosis post-Golgi vesicle-mediated transport protein transport vesicle docking
220942_x_at	0.256	10.841	2.187	4.475e-02	0.309	-4.070	FAM162A	family with sequence similarity 162, member A	3	123585712	NM_014367	26355	3q21.1	Hs.584881	8	membrane integral to membrane
221163_s_at	0.341	6.659	2.187	4.477e-02	0.309	-4.070	MLXIPL	MLX interacting protein-like	7	-72645459	NM_015977	51085	7q11.23	Hs.647055	24	transcription factor activity nucleus transcription factor complex cytoplasm protein kinase cascade transcription factor binding anatomical structure morphogenesis positive regulation of specific transcription from RNA polymerase II promoter transcription activator activity transcription repressor activity glucose homeostasis protein homodimerization activity positive regulation of fatty acid biosynthetic process positive regulation of glycolysis negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent protein heterodimerization activity
220415_at	-0.374	3.764	-2.187	4.477e-02	0.309	-4.070	TNNI3K	TNNI3 interacting kinase	1	74436534, 74473672	NM_015978	51086	1p31.1	Hs.480085	8	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleolus cytoplasm Golgi apparatus plasma membrane protein amino acid phosphorylation protein C-terminus binding transferase activity troponin I binding
225768_at	-0.811	7.005	-2.187	4.479e-02	0.309	-4.071	NR1D2	nuclear receptor subfamily 1, group D, member 2	3	23961754, 23962615	AI761621	9975	3p24.2	Hs.37288	13	transcription factor activity steroid hormone receptor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding
242224_at	-0.201	3.122	-2.187	4.480e-02	0.309	-4.071	GPATCH2	G patch domain containing 2	1	-215670456	R40111	55105	1q41	Hs.420757	6	nucleic acid binding intracellular
203482_at	-0.290	6.631	-2.186	4.481e-02	0.309	-4.071	FAM178A	family with sequence similarity 178, member A	10	102662315, 102662315, 102662315	AL133215	55719	10q24.31	Hs.447458	5
227598_at	0.203	3.757	2.186	4.485e-02	0.309	-4.072	C7orf29	chromosome 7 open reading frame 29	7	149657870	AI762857	113763	7q36.1	Hs.655915	4
203271_s_at	0.214	6.381	2.186	4.486e-02	0.309	-4.072	UNC119	unc-119 homolog (C. elegans)	17	-23897851	NM_005148	9094	17q11.2	Hs.410455	16	soluble fraction cytosol synaptic transmission visual perception phototransduction response to stimulus
215548_s_at	-0.295	7.866	-2.186	4.487e-02	0.309	-4.072	SCFD1	sec1 family domain containing 1	14	30161271	AB020724	23256	14q12	Hs.369168	17	cytoplasm endoplasmic reticulum Golgi apparatus vesicle docking during exocytosis protein transport membrane vesicle-mediated transport
207033_at	0.236	4.212	2.186	4.487e-02	0.309	-4.072	GIF	gastric intrinsic factor (vitamin B synthesis)	11	-59353321	NM_005142	2694	11q13	Hs.110014	13	extracellular region ion transport cobalt ion transport cobalt ion transmembrane transporter activity cobalamin transport cobalamin binding cobalt ion binding
223317_at	0.233	3.221	2.186	4.488e-02	0.309	-4.073	ALKBH7	alkB, alkylation repair homolog 7 (E. coli)	19	6323443	AA774555	84266	19p13.3	Hs.111099	5
229740_at	0.192	4.509	2.185	4.492e-02	0.309	-4.073	LOC643008	hypothetical protein LOC643008	17	71141108	BF478120	643008	17q25.1	Hs.528605	3
222702_x_at	-0.342	7.266	-2.185	4.492e-02	0.309	-4.073	CRIPT	cysteine-rich PDZ-binding protein	2	46697828	BF540954	9419	2p21	Hs.133998	11	cytoplasm cell junction cell projection dendritic spine synapse
211220_s_at	-0.694	4.581	-2.185	4.493e-02	0.309	-4.073	HSF2	heat shock transcription factor 2	6	122762394	BC005329	3298	6q22.31	Hs.158195	28	transcription factor activity transcription coactivator activity nucleus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter response to stress spermatogenesis protein homodimerization activity sequence-specific DNA binding
205039_s_at	0.222	6.700	2.185	4.495e-02	0.309	-4.074	IKZF1	IKAROS family zinc finger 1 (Ikaros)	7	50314923	NM_006060	10320	7p13-p11.1	Hs.435949 Hs.488251	52	DNA binding intracellular nucleus mesoderm development zinc ion binding regulation of transcription metal ion binding
226512_at	-0.258	6.615	-2.185	4.495e-02	0.309	-4.074	ZMYM2	zinc finger, MYM-type 2	13	19430809	AW340955	7750	13q11-q12	Hs.644041	29	protein binding cellular_component nucleus biological_process zinc ion binding PML body ubiquitin conjugating enzyme binding regulation of transcription metal ion binding
203583_at	-0.206	7.540	-2.185	4.496e-02	0.309	-4.074	UNC50	unc-50 homolog (C. elegans)	2	98591473	NM_014044	25972	2q11.2	Hs.13370	7	RNA binding nucleus Golgi apparatus protein transport membrane integral to membrane
227761_at	0.278	5.516	2.184	4.502e-02	0.310	-4.075	MYO5A	myosin VA (heavy chain 12, myoxin)	15	-50386774	AW235548	4644	15q21	Hs.21213 Hs.596221	47	microfilament motor activity nucleotide binding ruffle calmodulin binding ATP binding cytoplasm transport myosin complex actin filament-based movement growth cone neuron projection actin filament binding
200954_at	0.204	8.103	2.184	4.503e-02	0.310	-4.075	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	16	2503953	NM_001694	527	16p13.3	Hs.389107	23	protein binding vacuole ion transport ATP synthesis coupled proton transport proton transport membrane integral to membrane proton-transporting V-type ATPase, V0 domain interspecies interaction between organisms proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
227382_at	-0.245	4.134	-2.184	4.504e-02	0.310	-4.076	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	16	68015998	AA649048	80777	16q22.1	Hs.461131	7	mitochondrion mitochondrial outer membrane mitochondrial inner membrane microsome transport enzyme activator activity membrane integral to membrane heme binding electron transport chain metal ion binding
228112_at	0.208	4.836	2.183	4.507e-02	0.310	-4.076	DNAH1	dynein, axonemal, heavy chain 1	3	52325374	AI004779	25981	3p21.1	Hs.655469	7	nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme	Huntington's disease
211169_s_at	-0.750	5.281	-2.183	4.508e-02	0.310	-4.076	PPP1R3A	protein phosphatase 1, regulatory (inhibitor) subunit 3A	7	-113304117	AF024579	5506	7q31.1	Hs.458309	24	carbohydrate metabolic process glycogen metabolic process membrane integral to membrane	Insulin signaling pathway
220676_at	0.172	4.227	2.183	4.511e-02	0.310	-4.077	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	11	-129780027	NM_007037	11095	11q25	Hs.271605	9	metalloendopeptidase activity integrin binding extracellular region proteinaceous extracellular matrix proteolysis heparin binding peptidase activity zinc ion binding negative regulation of cell proliferation low affinity phosphate transmembrane transporter activity metal ion binding
227353_at	0.233	4.853	2.183	4.512e-02	0.310	-4.077	TMC8	transmembrane channel-like 8	17	73638453	BE671663	147138	17q25.3	Hs.592102	12	endoplasmic reticulum membrane integral to membrane
220110_s_at	0.251	3.560	2.183	4.513e-02	0.310	-4.077	NXF3	nuclear RNA export factor 3	X	-102217405	NM_022052	56000	Xq22-q23	Hs.60386	7	nucleotide binding mRNA binding protein binding intracellular nucleus cytoplasm transport poly(A)+ mRNA export from nucleus nuclear RNA export factor complex
212831_at	0.250	4.718	2.183	4.513e-02	0.310	-4.077	MEGF9	multiple EGF-like-domains 9	9	-122402911	BF110421	1955	9q32-q33.3	Hs.715550	4	receptor activity calcium ion binding cellular_component biological_process membrane integral to membrane
234414_at	0.313	6.821	2.183	4.515e-02	0.310	-4.078	FAM22F	family with sequence similarity 22, member F	9	-96120298	AL133071	54754	9q22.32	Hs.648183	1
1552708_a_at	-0.236	3.087	-2.182	4.517e-02	0.310	-4.078	DUSP19	dual specificity phosphatase 19	2	183651531	AB038770	142679	2q32.1	Hs.132237	7	inactivation of MAPK activity protein tyrosine phosphatase activity protein binding cytoplasm protein amino acid dephosphorylation JNK cascade protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity hydrolase activity
227001_at	0.362	4.408	2.182	4.518e-02	0.310	-4.078	NIPAL2	NIPA-like domain containing 2	8	-99273562	AI096706	79815	8q22.2	Hs.309489	3	membrane integral to membrane
205199_at	0.205	5.227	2.182	4.519e-02	0.310	-4.079	CA9	carbonic anhydrase IX	9	35663914	NM_001216	768	9p13-p12	Hs.63287	89	morphogenesis of an epithelium carbonate dehydratase activity nucleus nucleolus plasma membrane one-carbon metabolic process zinc ion binding integral to membrane lyase activity cell projection metal ion binding secretion	Nitrogen metabolism
211968_s_at	-0.356	9.335	-2.182	4.522e-02	0.310	-4.079	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14	-101616827, -101616827	AI962933	3320	14q32.33	Hs.525600 Hs.700831	275	nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly	Antigen processing and presentation Pathways in cancer Prostate cancer
219163_at	0.270	6.061	2.182	4.523e-02	0.310	-4.079	ZNF562	zinc finger protein 562	19	-9620337	NM_017656	54811	19p13.2	Hs.371107	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
217043_s_at	-0.282	6.634	-2.181	4.526e-02	0.310	-4.080	MFN1	mitofusin 1	3	180548173	U95822	55669	3q26.33	Hs.478383	16	nucleotide binding GTPase activity GTP binding cytoplasm mitochondrion mitochondrial outer membrane mitochondrial fusion biological_process membrane integral to membrane hydrolase activity
220329_s_at	-0.323	6.261	-2.181	4.528e-02	0.310	-4.080	RMND1	required for meiotic nuclear division 1 homolog (S. cerevisiae)	6	-151767681	NM_017909	55005	6q25.1	Hs.486835	5
210611_s_at	-0.422	6.975	-2.181	4.530e-02	0.310	-4.081	DTNA	dystrobrevin, alpha	18	30327251, 30327251, 30327251, 30427279, 30544193, 30589937, 30589937, 30652299, 30652299	U26744	1837	18q12	Hs.643454	38	calcium ion binding protein binding cytoplasm striated muscle contraction signal transduction neuromuscular synaptic transmission zinc ion binding cell junction synapse
1552301_a_at	-0.337	10.094	-2.181	4.531e-02	0.310	-4.081	CORO6	coronin 6	17	-24965899	NM_032854	84940	17q11.2	Hs.143046	7
220477_s_at	0.212	8.864	2.180	4.533e-02	0.310	-4.081	C20orf30	chromosome 20 open reading frame 30	20	-5028483	NM_014145	29058	20p13	Hs.719105	5	membrane integral to membrane
212330_at	-0.299	7.561	-2.180	4.533e-02	0.310	-4.081	TFDP1	transcription factor Dp-1	13	113287003, 113287056	R60866	7027	13q34	Hs.79353	37	transcription factor activity transcription coactivator activity nucleus nucleoplasm transcription factor complex regulation of transcription from RNA polymerase II promoter cell cycle transcription factor binding cell proliferation protein domain specific binding	Cell cycle TGF-beta signaling pathway
228506_at	-0.216	4.818	-2.180	4.534e-02	0.310	-4.081	NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	10	-123706592	AA009947	54780	10q26.13	Hs.258798	8
236886_at	0.198	4.413	2.180	4.534e-02	0.310	-4.081	LOC100049716	hypothetical protein LOC100049716	12		AI027546	100049716	12p13.33	Hs.655804	1
230543_at	0.270	3.018	2.180	4.534e-02	0.310	-4.081	USP9X	ubiquitin specific peptidase 9, X-linked	X	40829831	AI761675	8239	Xp11.4	Hs.77578	24	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm ubiquitin-dependent protein catabolic process transforming growth factor beta receptor signaling pathway female gamete generation peptidase activity protein deubiquitination BMP signaling pathway co-SMAD binding
217813_s_at	0.264	4.114	2.180	4.540e-02	0.311	-4.083	SPIN1	spindlin 1	9	90193116	NM_006717	10927	9q22.1-q22.3	Hs.146804	16	nucleus spindle cell cycle multicellular organismal development gamete generation
229989_at	0.189	4.022	2.179	4.542e-02	0.311	-4.083	FDXACB1	ferredoxin-fold anticodon binding domain containing 1	11	-111249989	AA805700	91893	11q23.1	Hs.697132	5	tRNA binding nucleotide binding magnesium ion binding phenylalanine-tRNA ligase activity ATP binding cytoplasm translation phenylalanyl-tRNA aminoacylation tRNA processing
225179_at	-0.359	7.146	-2.179	4.543e-02	0.311	-4.083	UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	4	39376058	AA161140	3093	4p14	Hs.50308 Hs.714332	20	nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding cytoplasm ubiquitin-dependent protein catabolic process ligase activity ubiquitin protein ligase binding post-translational protein modification regulation of protein metabolic process	Ubiquitin mediated proteolysis
221430_s_at	-0.391	6.086	-2.179	4.543e-02	0.311	-4.083	RNF146	ring finger protein 146	6	127629712	NM_030963	81847	6q22.1-q22.33	Hs.267120	12	protein binding zinc ion binding metal ion binding
218751_s_at	-0.349	7.217	-2.179	4.544e-02	0.311	-4.083	FBXW7	F-box and WD repeat domain containing 7	4	-153461859, -153461859, -153461859	NM_018315	55294	4q31.3	Hs.679796	71	protein binding nucleus protein ubiquitination modification-dependent protein catabolic process	Ubiquitin mediated proteolysis
219059_s_at	0.455	5.103	2.179	4.544e-02	0.311	-4.083	LYVE1	lymphatic vessel endothelial hyaluronan receptor 1	11	-10535988	AL574194	10894	11p15	Hs.655332 Hs.708807	25	transmembrane receptor activity binding hyaluronic acid binding membrane fraction plasma membrane integral to plasma membrane glycosaminoglycan catabolic process transport cell motion cell adhesion cell-matrix adhesion response to wounding anatomical structure morphogenesis
209966_x_at	0.609	6.509	2.179	4.545e-02	0.311	-4.084	ESRRG	estrogen-related receptor gamma	1	-214743218, -214743218, -214743210, -214743210	AF094518	2104	1q41	Hs.444225	32	transcription factor activity steroid hormone receptor activity steroid binding protein binding nucleus zinc ion binding transcription activator activity sequence-specific DNA binding positive regulation of transcription, DNA-dependent metal ion binding AF-2 domain binding
202495_at	-0.376	7.788	-2.179	4.546e-02	0.311	-4.084	TBCC	tubulin folding cofactor C	6	-42820211	NM_003192	6903	6pter-p12.1	Hs.75064	6	binding cytoskeleton microtubule post-chaperonin tubulin folding pathway chaperone binding
225168_at	0.234	5.050	2.179	4.547e-02	0.311	-4.084	FRMD4A	FERM domain containing 4A	10	-13725711	T78406	55691	10p13	Hs.330463 Hs.656573	3	binding cytoplasm cytoskeleton
206601_s_at	0.219	3.310	2.178	4.550e-02	0.311	-4.084	HOXD3	homeobox D3	2	176737050	BC005124	3232	2q31.1	Hs.93574	25	transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding positive regulation of neuron differentiation embryonic skeletal system morphogenesis cartilage development
228091_at	-0.191	5.660	-2.178	4.550e-02	0.311	-4.085	STX17	syntaxin 17	9	101708735	AI800609	55014	9q31.1	Hs.709465	7	SNAP receptor activity nucleolus endoplasmic reticulum intracellular protein transport membrane integral to membrane vesicle-mediated transport	SNARE interactions in vesicular transport
211605_s_at	0.221	5.807	2.178	4.552e-02	0.311	-4.085	RARA	retinoic acid receptor, alpha	17	35718971, 35728022, 35751867	U41742	5914	17q21	Hs.654583	187	retinoic acid binding transcription factor activity steroid hormone receptor activity retinoic acid receptor activity transcription coactivator activity protein binding nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding cell surface estrogen receptor signaling pathway response to estradiol stimulus response to retinoic acid negative regulation of interferon-gamma production negative regulation of tumor necrosis factor production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-5 production sequence-specific DNA binding positive regulation of T-helper 2 cell differentiation regulation of anti-apoptosis metal ion binding retinoic acid receptor signaling pathway perinuclear region of cytoplasm	Pathways in cancer Acute myeloid leukemia
217827_s_at	-0.474	8.679	-2.178	4.553e-02	0.311	-4.085	SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	15	-63042415, -63042415	NM_016630	51324	15q21-q22	Hs.242458	10	cytoplasm endosome Golgi apparatus cytosol cytosol cell death membrane trans-Golgi network transport vesicle trans-Golgi network transport vesicle CD4 receptor binding CD4 receptor binding antigen receptor-mediated signaling pathway
232617_at	0.362	5.837	2.178	4.554e-02	0.311	-4.085	CTSS	cathepsin S	1	-148969175	AK024855	1520	1q21	Hs.181301	62	cysteine-type endopeptidase activity extracellular region lysosome proteolysis immune response peptidase activity membrane intracellular membrane-bounded organelle	Lysosome Antigen processing and presentation
1559603_at	-0.266	4.149	-2.178	4.555e-02	0.311	-4.085	GPR12	G protein-coupled receptor 12	13	-26227340	BQ717575	2835	13q12	Hs.123034 Hs.719715	7	lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane cellular calcium ion homeostasis signal transduction G-protein coupled receptor protein signaling pathway
223731_at	0.320	3.915	2.178	4.555e-02	0.311	-4.085	MYCBPAP	MYCBP associated protein	17	45940743	AL136765	84073	17q21.33	Hs.398196 Hs.716159	5	protein binding cytoplasm synaptic transmission multicellular organismal development spermatogenesis membrane cell differentiation
202499_s_at	0.394	3.900	2.178	4.556e-02	0.311	-4.086	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	12	-7963091	NM_006931	6515	12p13.3	Hs.419240	31	transporter activity glucose transmembrane transporter activity cytoplasm plasma membrane carbohydrate metabolic process carbohydrate transport glucose transport integral to membrane substrate-specific transmembrane transporter activity transmembrane transport
212914_at	-0.364	7.956	-2.178	4.557e-02	0.311	-4.086	CBX7	chromobox homolog 7	22	-37856724	AV648364	23492	22q13.1	Hs.356416	8	chromatin chromatin binding nucleus chromatin assembly or disassembly chromatin modification regulation of transcription
206338_at	0.277	5.919	2.177	4.559e-02	0.311	-4.086	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	19	-11423142	NM_001420	1995	19p13.2	Hs.1701	8	nucleotide binding RNA binding multicellular organismal development nervous system development cell differentiation
214267_s_at	0.256	4.851	2.177	4.561e-02	0.311	-4.087	CADM4	cell adhesion molecule 4	19	-48818361	AI050793	199731	19q13.31	Hs.370984	3	protein binding cell adhesion membrane integral to membrane
1565772_at	0.229	4.807	2.177	4.564e-02	0.311	-4.087	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	11	-76710707	AL042444	5058	11q13-q14	Hs.435714	190	MAPKKK cascade nucleotide binding protein serine/threonine kinase activity collagen binding ATP binding cytoplasm Golgi apparatus plasma membrane focal adhesion apoptosis ER-nuclear signaling pathway cytoskeleton organization transferase activity cell junction positive regulation of JUN kinase activity protein amino acid autophosphorylation	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Axon guidance Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma
207078_at	-0.556	5.290	-2.177	4.564e-02	0.311	-4.087	MED6	mediator complex subunit 6	14	-70120709	NM_005466	10001	14q24.2	Hs.497353	22	RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter
211987_at	-0.353	8.786	-2.177	4.565e-02	0.311	-4.087	TOP2B	topoisomerase (DNA) II beta 180kDa	3	-25614478	NM_001068	7155	3p24	Hs.475733	55	nucleotide binding heterochromatin neuron migration chromatin binding DNA topoisomerase (ATP-hydrolyzing) activity protein kinase C binding ATP binding nucleus nucleoplasm chromosome nucleolus cytoplasm cytosol DNA topological change axonogenesis protein C-terminus binding forebrain development histone deacetylase binding protein heterodimerization activity
204145_at	-0.228	7.270	-2.177	4.565e-02	0.311	-4.087	FRG1	FSHD region gene 1	4	191098967	NM_004477	2483	4q35	Hs.203772	11	nucleus spliceosomal complex nucleolus rRNA processing mRNA processing RNA splicing Cajal body nuclear speck
206875_s_at	-0.338	7.680	-2.177	4.565e-02	0.311	-4.087	SLK	STE20-like kinase (yeast)	10	105717459	NM_014720	9748	10q24.33	Hs.591922	16	nucleotide binding DNA binding nuclease activity protein serine/threonine kinase activity ATP binding cytoplasm plasma membrane nucleotide-excision repair protein amino acid phosphorylation apoptosis transferase activity
208701_at	0.251	4.195	2.177	4.566e-02	0.311	-4.088	APLP2	amyloid beta (A4) precursor-like protein 2	11	129444925	BC000373	334	11q23-q25 11q24	Hs.709184	43	DNA binding serine-type endopeptidase inhibitor activity nucleus plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane peptidase inhibitor activity identical protein binding
234732_s_at	0.175	2.423	2.176	4.568e-02	0.311	-4.088	EFCAB6	EF-hand calcium binding domain 6	22	-42255986	AL355841	64800	22q13.1-q13.33	Hs.658996	10	calcium ion binding nucleus regulation of transcription
201204_s_at	0.335	6.224	2.176	4.568e-02	0.311	-4.088	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	20	-17542322	AA706065	6238	20p12	Hs.472213	19	receptor activity endoplasmic reticulum ribosome translation signal transduction protein transport membrane integral to membrane integral to endoplasmic reticulum membrane intracellular protein transmembrane transport
218868_at	-0.211	5.920	-2.176	4.569e-02	0.311	-4.088	ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)	7	152087783	NM_020445	57180	7q36.1	Hs.647117	8	nucleotide binding actin binding protein binding ATP binding cytoplasm cytoskeleton regulation of actin filament polymerization cell projection
235367_at	-0.467	8.917	-2.176	4.570e-02	0.311	-4.088	MYPN	myopalladin	10	69539255	BF109970	84665	10q21.3	Hs.55205	12	actin binding nucleus cytoplasm sarcomere
216779_at	0.141	3.685	2.176	4.570e-02	0.311	-4.088	CYLC1	cylicin, basic protein of sperm head cytoskeleton 1	X	83002825	Z22780	1538	Xq21.1	Hs.444230	6	structural molecule activity cytoplasm cytoskeleton multicellular organismal development spermatogenesis cell differentiation cytoskeletal calyx acrosomal matrix
208654_s_at	-0.512	7.348	-2.176	4.571e-02	0.311	-4.089	CD164	CD164 molecule, sialomucin	6	-109794411	BF669455	8763	6q21	Hs.520313 Hs.644693	17	extracellular region plasma membrane integral to plasma membrane immune response cell adhesion heterophilic cell adhesion signal transduction multicellular organismal development negative regulation of cell proliferation	Lysosome
212737_at	0.262	7.042	2.176	4.571e-02	0.311	-4.089	GM2A	GM2 ganglioside activator	5	150612805	AL513583	2760	5q31.3-q33.1	Hs.483873	32	lipid transporter activity cytoplasm mitochondrion lysosome hydrogen:potassium-exchanging ATPase complex lipid metabolic process ganglioside catabolic process lipid transport learning or memory oligosaccharide catabolic process internal side of plasma membrane phospholipase activator activity glycolipid catabolic process lipid storage sphingolipid catabolic process sphingolipid activator protein activity beta-N-acetylgalactosaminidase activity apical cortex neurological system process neuromuscular process controlling balance positive regulation of hydrolase activity	Lysosome
204905_s_at	0.367	7.054	2.176	4.572e-02	0.311	-4.089	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	6	-8024634, -8018593	NM_004280	9521	6p24.3-p25.1	Hs.602353 Hs.719206	10	protein binding nucleus cytoplasm translation negative regulation of cell proliferation positive regulation of apoptosis positive regulation of DNA damage response, signal transduction by p53 class mediator
226303_at	-0.538	7.714	-2.176	4.572e-02	0.311	-4.089	PGM5	phosphoglucomutase 5	9	70161634	AA706788	5239	9q13	Hs.307835	8	magnesium ion binding stress fiber phosphoglucomutase activity structural molecule activity protein binding spot adherens junction focal adhesion carbohydrate metabolic process glucose metabolic process cell adhesion biological_process internal side of plasma membrane intercalated disc dystrophin-associated glycoprotein complex cell junction sarcolemma costamere
201067_at	-0.343	8.272	-2.176	4.574e-02	0.311	-4.089	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	7	102775324	BF215487	5701	7q22.1-q22.3	Hs.437366	56	nucleotide binding proteasome complex protein binding ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
224059_s_at	0.226	5.489	2.176	4.575e-02	0.311	-4.089	NUMBL	numb homolog (Drosophila)-like	19	-45863651	BC001794	9253	19q13.13-q13.2	Hs.326953	15	protein binding cytoplasm nervous system development neuroblast proliferation axonogenesis forebrain development adherens junction organization	Notch signaling pathway
218713_at	-0.327	5.778	-2.175	4.576e-02	0.311	-4.089	NARG2	NMDA receptor regulated 2	15	-58499099	NM_024611	79664	15q22.2	Hs.200943	6	nucleus
205529_s_at	0.313	5.509	2.175	4.577e-02	0.311	-4.090	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	8	-93040327, -93040327, -93040327, -93040327	NM_004349	862	8q22	Hs.368431	85	transcription factor activity protein binding nucleus generation of precursor metabolites and energy regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity protein homodimerization activity fat cell differentiation metal ion binding regulation of DNA binding	Pathways in cancer Acute myeloid leukemia
224844_at	-0.321	9.039	-2.175	4.580e-02	0.312	-4.090	SLAIN2	SLAIN motif family, member 2	4	48038369	BE551691	57606	4p11	Hs.479677	5
200670_at	0.317	6.722	2.175	4.582e-02	0.312	-4.091	XBP1	X-box binding protein 1	22	-27520547	NM_005080	7494	22q12 22q12.1	Hs.437638	80	transcription factor activity nucleus regulation of transcription, DNA-dependent immune response sequence-specific DNA binding protein dimerization activity
219730_at	-0.372	4.784	-2.175	4.583e-02	0.312	-4.091	MED18	mediator complex subunit 18	1	28528099	NM_017638	54797	1p35.3	Hs.479911	6	nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity identical protein binding regulation of transcription
217486_s_at	-0.277	4.237	-2.174	4.585e-02	0.312	-4.091	ZDHHC17	zinc finger, DHHC-type containing 17	12	75681984	AF161412	23390	12q21.2	Hs.4014	12	signal transducer activity signal transducer activity protein binding cytoplasm Golgi apparatus zinc ion binding membrane integral to membrane transferase activity protein palmitoylation protein-cysteine S-palmitoleyltransferase activity cytoplasmic vesicle lipoprotein transport positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
225384_at	-0.391	5.390	-2.174	4.587e-02	0.312	-4.092	DOCK7	dedicator of cytokinesis 7	1	-62692984	BF001267	85440	1p31.3	Hs.406156	15	microtubule cytoskeleton organization guanyl-nucleotide exchange factor activity GTP binding multicellular organismal development nervous system development axonogenesis cell differentiation axon growth cone neuron projection development activation of Rac GTPase activity positive regulation of peptidyl-serine phosphorylation basal part of cell establishment of neuroblast polarity Rac GTPase binding GTPase binding
202217_at	0.401	10.519	2.174	4.587e-02	0.312	-4.092	C21orf33	chromosome 21 open reading frame 33	21	44377921	NM_004649	8209	21q22.3	Hs.413482	13	mitochondrion
1565685_at	-0.146	2.573	-2.174	4.588e-02	0.312	-4.092	LOC400940	hypothetical LOC400940	2	6039560	AA774300	400940	2p25.2	Hs.378814	2
227692_at	0.597	5.767	2.174	4.589e-02	0.312	-4.092	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	7	79602075	AU153866	2770	7q21	Hs.134587	85	nucleotide binding GTPase activity signal transducer activity protein binding GTP binding intracellular heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding	Chemokine signaling pathway Axon guidance Tight junction Gap junction Leukocyte transendothelial migration Long-term depression Melanogenesis
203519_s_at	-0.344	7.727	-2.173	4.595e-02	0.312	-4.093	UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	10	-12002027, -12002026	NM_015542	26019	10p14-p13	Hs.370689 Hs.610110	31	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay RNA binding nucleus cytoplasm mRNA export from nucleus RNA metabolic process identical protein binding perinuclear region of cytoplasm
225404_at	-0.342	8.519	-2.173	4.597e-02	0.312	-4.093	C1orf212	chromosome 1 open reading frame 212	1	-35091710	R75637	113444	1p34.3	Hs.27160 Hs.595007 Hs.661594	2	membrane integral to membrane
206957_at	0.222	3.046	2.173	4.597e-02	0.312	-4.094	AGXT	alanine-glyoxylate aminotransferase	2	241456834	NM_016236	189	2q36-q37	Hs.144567	44	serine-pyruvate transaminase activity protein binding mitochondrion mitochondrial matrix peroxisome protein targeting to peroxisome metabolic process alanine-glyoxylate transaminase activity response to hormone stimulus amino acid binding transferase activity glycine biosynthetic process, by transamination of glyoxylate pyridoxal phosphate binding protein homodimerization activity pyruvate biosynthetic process glyoxylate metabolic process oxalic acid secretion response to glucocorticoid stimulus response to cAMP	Alanine, aspartate and glutamate metabolism Glycine, serine and threonine metabolism Metabolic pathways
227760_at	0.273	4.003	2.173	4.599e-02	0.312	-4.094	IGFBPL1	insulin-like growth factor binding protein-like 1	9	-38398990	AL522781	347252	9p13.1	Hs.349705	3	regulation of cell growth insulin-like growth factor binding extracellular region
201326_at	-0.355	8.556	-2.173	4.599e-02	0.312	-4.094	CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	7	56086871	BE737030	908	7p11.2	Hs.82916	17	nucleotide binding ATP binding cytoplasm chaperonin-containing T-complex protein folding unfolded protein binding
201811_x_at	0.575	8.105	2.173	4.600e-02	0.312	-4.094	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	3	-15271360, -15271360	NM_004844	9467	3p24.3	Hs.257761 Hs.719150	11	protein kinase inhibitor activity protein binding cytoplasm mitochondrion intracellular signaling cascade SH3 domain binding
217764_s_at	0.433	6.020	2.173	4.601e-02	0.312	-4.094	RAB31	RAB31, member RAS oncogene family	18	9698227	AF183421	11031	18p11.3	Hs.714730 Hs.99528	13	nucleotide binding GTPase activity GTP binding plasma membrane small GTPase mediated signal transduction protein transport	Endocytosis
216096_s_at	-0.259	3.252	-2.172	4.603e-02	0.312	-4.095	NRXN1	neurexin 1	2	-49999147, -49999147	AF064842	9378	2p16.3	Hs.637685	36	receptor activity calcium ion binding protein binding protein binding integral to plasma membrane cell adhesion axon guidance membrane integral to membrane	Cell adhesion molecules (CAMs)
204229_at	0.175	6.364	2.172	4.604e-02	0.312	-4.095	SLC17A7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	19	-54624467	H40895	57030	19q13	Hs.375616	16	ion transport sodium ion transport phosphate transport neurotransmitter transport symporter activity sodium:inorganic phosphate symporter activity sodium-dependent phosphate transmembrane transporter activity membrane integral to membrane synaptosome cell junction synaptic vesicle membrane sodium ion binding cytoplasmic vesicle sequestering of neurotransmitter excitatory synapse
238478_at	0.354	5.713	2.172	4.604e-02	0.312	-4.095	BNC2	basonuclin 2	9	-16399500	H97386	54796	9p22.3-p22.2	Hs.656581 Hs.693437	10	intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding
225775_at	0.231	6.658	2.172	4.604e-02	0.312	-4.095	TSPAN33	tetraspanin 33	7	128571947	AK000208	340348	7q32.1	Hs.27267	6	membrane integral to membrane
238039_at	0.239	4.326	2.172	4.604e-02	0.312	-4.095	LOC728769	hypothetical protein LOC728769	5		BG180437	728769	5q14.1	Hs.586193
232149_s_at	-0.312	5.613	-2.172	4.605e-02	0.312	-4.095	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	8	-59658619, -59658619	BF056507	8439	8q12-q13	Hs.372000	8	receptor signaling protein activity soluble fraction cytoplasm ceramide metabolic process signal transduction
224311_s_at	-0.605	5.702	-2.172	4.605e-02	0.312	-4.095	CAB39	calcium binding protein 39	2	231285800, 231286506	AF151824	51719	2q37.1	Hs.632536	14	protein binding cytoplasm	mTOR signaling pathway
205257_s_at	0.200	5.170	2.172	4.605e-02	0.312	-4.095	AMPH	amphiphysin	7	-38389829	NM_001635	273	7p14-p13	Hs.592182	38	protein binding cytoplasm synaptic transmission learning synaptic vesicle actin cytoskeleton membrane cell junction cytoplasmic vesicle synapse synaptic vesicle endocytosis	Fc gamma R-mediated phagocytosis
230359_at	0.176	5.518	2.172	4.607e-02	0.312	-4.096	KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	10	134823960	N45097	85442	10q26.3	Hs.530685	3	molecular_function guanyl-nucleotide exchange factor activity cellular_component intracellular biological_process regulation of small GTPase mediated signal transduction
43544_at	-0.373	6.221	-2.172	4.608e-02	0.312	-4.096	MED16	mediator complex subunit 16	19	-818961	AA314406	10025	19p13.3	Hs.365207	13	transcription coactivator activity receptor activity nucleus regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter thyroid hormone receptor coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription thyroid hormone receptor binding
219236_at	0.240	5.607	2.172	4.610e-02	0.312	-4.096	PAQR6	progestin and adipoQ receptor family member VI	1	-154479833, -154479830	NM_024897	79957	1q22	Hs.235873	5	receptor activity membrane integral to membrane
209443_at	0.878	7.072	2.172	4.610e-02	0.312	-4.096	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	14	94117483	J02639	5104	14q32.1	Hs.159628	62	protease binding serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular region spermatogenesis fusion of sperm to egg plasma membrane heparin binding membrane peptidase inhibitor activity acrosin binding protein complex negative regulation of proteolysis	Complement and coagulation cascades
227514_at	-0.376	5.953	-2.171	4.612e-02	0.312	-4.096	ITPRIPL2	inositol 1,4,5-triphosphate receptor interacting protein-like 2	16	19032754	AI766311	162073	16p12.3	Hs.530899 Hs.648523	3	membrane integral to membrane
215560_x_at	-0.183	4.650	-2.171	4.613e-02	0.313	-4.097	MTRF1L	mitochondrial translational release factor 1-like	6	-153350092	AU145135	54516	6q25-q26	Hs.225836 Hs.304818	9	cytoplasm mitochondrion translational termination translation release factor activity, codon specific
203531_at	-0.288	10.438	-2.171	4.613e-02	0.313	-4.097	CUL5	cullin 5	11	107384617	BF435809	8065	11q22-q23	Hs.440320 Hs.701122	38	G1/S transition of mitotic cell cycle receptor activity calcium channel activity protein binding cytosol ubiquitin-dependent protein catabolic process cell cycle arrest negative regulation of cell proliferation induction of apoptosis by intracellular signals cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding interspecies interaction between organisms	Ubiquitin mediated proteolysis
1559060_a_at	-0.434	5.104	-2.171	4.616e-02	0.313	-4.097	FNIP1	folliculin interacting protein 1	5	-131005305	BF677986	96459	5q23.3	Hs.591273	4	cytoplasm
210834_s_at	-0.208	3.349	-2.171	4.618e-02	0.313	-4.097	PTGER3	prostaglandin E receptor 3 (subtype EP3)	1	-71244124, -71209051, -71190702, -71090623	D38299	5733	1p31.2	Hs.445000	45	ligand-dependent nuclear receptor activity G-protein coupled receptor activity prostaglandin E receptor activity nuclear envelope plasma membrane integral to plasma membrane transcription, DNA-dependent signal transduction G-protein coupled receptor protein signaling pathway cell death	Calcium signaling pathway Neuroactive ligand-receptor interaction
229112_at	0.192	6.107	2.171	4.619e-02	0.313	-4.098	SIRT5	sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)	6	13682770, 13682853	AW300354	23408	6p23	Hs.567431 Hs.594133	13	NAD+ ADP-ribosyltransferase activity mitochondrion chromatin silencing protein amino acid ADP-ribosylation protein amino acid deacetylation zinc ion binding hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides regulation of transcription metal ion binding NAD binding
218807_at	0.218	5.206	2.170	4.621e-02	0.313	-4.098	VAV3	vav 3 guanine nucleotide exchange factor	1	-107915304, -107915304	NM_006113	10451	1p13.3	Hs.267659	21	SH3/SH2 adaptor activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular small GTPase mediated signal transduction zinc ion binding diacylglycerol binding regulation of Rho protein signal transduction metal ion binding	Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton
241746_at	0.192	4.368	2.170	4.622e-02	0.313	-4.098	CUL7	cullin 7	6	-43113332	AW081304	9820	6p21.1	Hs.520136	17	vasculogenesis protein binding anaphase-promoting complex cytoplasm proteolysis ubiquitin-dependent protein catabolic process regulation of mitotic metaphase/anaphase transition cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding	Ubiquitin mediated proteolysis
226636_at	0.362	4.942	2.170	4.622e-02	0.313	-4.098	PLD1	phospholipase D1, phosphatidylcholine-specific	3	-172801311	AI378587	5337	3q26	Hs.382865	84	phospholipase D activity protein binding cytoplasm endosome endoplasmic reticulum Golgi apparatus chemotaxis cell communication Ras protein signal transduction metabolic process membrane lipid catabolic process hydrolase activity phosphoinositide binding perinuclear region of cytoplasm NAPE-specific phospholipase D activity	Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways Endocytosis Fc gamma R-mediated phagocytosis GnRH signaling pathway Pathways in cancer Pancreatic cancer
230368_at	0.241	5.606	2.170	4.622e-02	0.313	-4.098	ERF	Ets2 repressor factor	19	-47443556	T73730	2077	19q13	Hs.655969	17	transcription factor activity ligand-regulated transcription factor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter cell proliferation sequence-specific DNA binding
211837_s_at	0.246	6.449	2.170	4.623e-02	0.313	-4.098	PTCRA	pre T-cell antigen receptor alpha	6	42991704	AF165312	171558	6p21.3	Hs.169002	12	receptor activity membrane integral to membrane negative regulation of thymocyte apoptosis	Notch signaling pathway
233496_s_at	-0.311	10.678	-2.170	4.623e-02	0.313	-4.098	CFL2	cofilin 2 (muscle)	14	-34249338, -34249338, -34249338	AV726166	1073	14q12	Hs.180141	20	actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix	Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
208524_at	0.189	4.539	2.170	4.625e-02	0.313	-4.099	GPR15	G protein-coupled receptor 15	3	99733567	NM_005290	2838	3q11.2-q13.1	Hs.563128	11	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway purinergic nucleotide receptor activity, G-protein coupled
203022_at	0.296	5.552	2.170	4.625e-02	0.313	-4.099	RNASEH2A	ribonuclease H2, subunit A	19	12778427	NM_006397	10535	19p13.2	Hs.532851	8	RNA binding endonuclease activity ribonuclease H activity ribonuclease activity nucleus DNA replication RNA catabolic process hydrolase activity metal ion binding	DNA replication
236927_at	0.248	3.969	2.170	4.626e-02	0.313	-4.099	SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	9	-112167349	BF436117	79987	9q32	Hs.522334 Hs.606771	5	chromatin binding calcium ion binding protein binding extracellular region cytoplasm cell adhesion membrane
232033_at	-0.219	5.810	-2.170	4.626e-02	0.313	-4.099	USP37	ubiquitin specific peptidase 37	2	-219023217	BE670098	57695	2q35	Hs.166068	13	ubiquitin thiolesterase activity nucleus ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
218630_at	0.152	5.884	2.170	4.628e-02	0.313	-4.099	MKS1	Meckel syndrome, type 1	17	-53637796	NM_017777	54903	17q22	Hs.408843	13
223636_at	0.370	4.534	2.170	4.628e-02	0.313	-4.099	ZMYND12	zinc finger, MYND-type containing 12	1	-42668589	AL136858	84217	1p34.2	Hs.294009	5	binding intracellular zinc ion binding metal ion binding
218502_s_at	-0.235	5.960	-2.170	4.628e-02	0.313	-4.099	TRPS1	trichorhinophalangeal syndrome I	8	-116489899	NM_014112	7227	8q24.12	Hs.657018	22	skeletal system development transcription factor activity protein binding intracellular nucleus transcription from RNA polymerase II promoter NLS-bearing substrate import into nucleus zinc ion binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent metal ion binding
208848_at	-0.421	7.788	-2.169	4.629e-02	0.313	-4.100	ADH5	alcohol dehydrogenase 5 (class III), chi polypeptide	4	-100211152	M30471	128	4q21-q25	Hs.78989	33	retinoid metabolic process respiratory system process alcohol dehydrogenase (NAD) activity binding fatty acid binding cytoplasm mitochondrion ethanol oxidation zinc ion binding electron carrier activity oxidoreductase activity peptidyl-cysteine S-nitrosylation formaldehyde dehydrogenase activity response to lipopolysaccharide protein homodimerization activity positive regulation of blood pressure formaldehyde catabolic process metal ion binding response to nitrosative stress response to redox state S-(hydroxymethyl)glutathione dehydrogenase activity oxidation reduction	Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Methane metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways
214617_at	0.232	6.133	2.169	4.631e-02	0.313	-4.100	PRF1	perforin 1 (pore forming protein)	10	-72027109	AI445650	5551	10q22	Hs.2200	88	calcium ion binding apoptosis cellular defense response circadian rhythm pathogenesis membrane integral to membrane cytoplasmic membrane-bounded vesicle cytolysis response to ethanol	Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease
219025_at	0.337	6.313	2.169	4.634e-02	0.313	-4.101	CD248	CD248 molecule, endosialin	11	-65838533	NM_020404	57124	11q13	Hs.195727	17	binding calcium ion binding sugar binding proteinaceous extracellular matrix cytoplasm biological_process membrane integral to membrane
201818_at	0.184	5.859	2.169	4.637e-02	0.313	-4.101	LPCAT1	lysophosphatidylcholine acyltransferase 1	5	-1514541	NM_024830	79888	5p15.33	Hs.368853	9	calcium ion binding endoplasmic reticulum Golgi apparatus metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-alkylglycerophosphocholine O-acetyltransferase activity
211631_x_at	0.186	4.003	2.169	4.637e-02	0.313	-4.101	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	9	-33100638	M22921	2683	9p13	Hs.272011	41	Golgi trans cisterna epithelial cell development acute inflammatory response beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity N-acetyllactosamine synthase activity lactose synthase activity extracellular region Golgi apparatus plasma membrane carbohydrate metabolic process lactose biosynthetic process galactose metabolic process protein amino acid terminal N-glycosylation cell adhesion binding of sperm to zona pellucida penetration of zona pellucida cytoskeletal protein binding negative regulation of cell proliferation glycoprotein biosynthetic process oligosaccharide biosynthetic process oligosaccharide biosynthetic process external side of plasma membrane integral to membrane basolateral plasma membrane transferase activity, transferring glycosyl groups desmosome glycocalyx manganese ion binding extracellular matrix organization mammary gland development brush border membrane development of secondary sexual characteristics metal ion binding branching morphogenesis of a tube leukocyte migration regulation of cell motion regulation of acrosome reaction positive regulation of epithelial cell proliferation involved in wound healing angiogenesis involved in wound healing positive regulation of apoptosis involved in mammary gland involution	Galactose metabolism N-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways
203386_at	-0.305	8.755	-2.168	4.638e-02	0.313	-4.101	TBC1D4	TBC1 domain family, member 4	13	-74756809	AI650848	9882	13q22.2	Hs.210891	26	GTPase activator activity Rab GTPase activator activity intracellular cytoplasm regulation of Rab GTPase activity
208562_s_at	-0.229	4.642	-2.168	4.638e-02	0.313	-4.101	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	12	-21849374, -21841590	NM_020297	10060	12p12.1	Hs.446050	35	nucleotide binding receptor activity transporter activity ATP binding transport sulfonylurea receptor activity ATP-sensitive potassium channel complex potassium ion import potassium channel regulator activity membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances defense response to virus	ABC transporters
206643_at	-0.178	3.544	-2.168	4.639e-02	0.313	-4.102	HAL	histidine ammonia-lyase	12	-94891272	NM_002108	3034	12q22-q24.1	Hs.190783	9	histidine ammonia-lyase activity histidine ammonia-lyase activity soluble fraction cytoplasm cytosol histidine catabolic process biosynthetic process ammonia ligase activity lyase activity	Histidine metabolism Nitrogen metabolism Metabolic pathways
226169_at	0.321	6.244	2.168	4.640e-02	0.313	-4.102	SBF2	SET binding factor 2	11	-9756789	AW276572	81846	11p15.4	Hs.577252	14	protein binding cytoplasm vacuolar membrane membrane dephosphorylation phosphatase activity phosphatase regulator activity phosphatase binding phosphoinositide binding myelination protein homodimerization activity protein tetramerization
202908_at	0.197	6.655	2.168	4.640e-02	0.313	-4.102	WFS1	Wolfram syndrome 1 (wolframin)	4	6322477	NM_006005	7466	4p16	Hs.518602 Hs.716556	86	kidney development renal water homeostasis endoplasmic reticulum ER overload response ER overload response visual perception sensory perception of sound membrane integral to membrane protein maturation by protein folding integral to endoplasmic reticulum membrane dendrite endoplasmic reticulum calcium ion homeostasis glucose homeostasis negative regulation of programmed cell death negative regulation of neuron apoptosis neurological system process ATPase binding positive regulation of protein metabolic process positive regulation of calcium ion transport calcium ion homeostasis
238316_at	0.259	3.748	2.168	4.640e-02	0.313	-4.102	ZNF567	zinc finger protein 567	19	41872141	BF061829	163081	19q13.12	Hs.412517	4	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1552343_s_at	-0.471	6.595	-2.168	4.643e-02	0.313	-4.102	PDE7A	phosphodiesterase 7A	8	-66796607, -66792459	NM_002604	5150	8q13	Hs.527119	16	cell fraction 3',5'-cyclic-AMP phosphodiesterase activity signal transduction hydrolase activity	Purine metabolism
224683_at	0.257	6.064	2.168	4.643e-02	0.313	-4.102	FBXO18	F-box protein, helicase, 18	10	5972219, 5976354	BE961916	84893	10p15.1	Hs.498543	7	nucleotide binding DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus DNA repair hydrolase activity modification-dependent protein catabolic process
1562490_at	-0.173	2.449	-2.168	4.644e-02	0.313	-4.102	THEM5	thioesterase superfamily member 5	1	-150086200	AK095283	284486	1q21.3	Hs.132648	2	hydrolase activity
209831_x_at	-0.250	6.929	-2.168	4.644e-02	0.313	-4.102	DNASE2	deoxyribonuclease II, lysosomal	19	-12847024	AB004574	1777	19p13.2	Hs.118243	27	DNA binding endodeoxyribonuclease activity deoxyribonuclease II activity protein binding lysosome DNA catabolic process apoptosis multicellular organismal development hydrolase activity erythrocyte differentiation	Lysosome
214493_s_at	-0.335	4.578	-2.168	4.645e-02	0.313	-4.103	INADL	InaD-like (Drosophila)	1	61980736	NM_005799	10207	1p31.3	Hs.478125	24	protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction	Tight junction
241140_at	-0.207	5.341	-2.168	4.645e-02	0.313	-4.103	LMO7	LIM domain 7	13	75092570, 75232797	AA702962	4008	13q22.2	Hs.207631	18	ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm zinc ion binding protein ubiquitination metal ion binding	Adherens junction
201646_at	-0.402	7.181	-2.167	4.646e-02	0.313	-4.103	SCARB2	scavenger receptor class B, member 2	4	-77298917	AA885297	950	4q21.1	Hs.349656 Hs.714206	24	receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane	Lysosome
210680_s_at	-0.194	5.150	-2.167	4.647e-02	0.313	-4.103	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	3	-188447299, -188434565, -188418631	D17525	5648	3q27-q28	Hs.89983	30	complement activation, lectin pathway complement activation, lectin pathway serine-type endopeptidase activity calcium ion binding extracellular region extracellular region extracellular space proteolysis peptidase activity protein homodimerization activity calcium-dependent protein binding	Complement and coagulation cascades
202116_at	-0.208	7.182	-2.167	4.648e-02	0.313	-4.103	DPF2	D4, zinc and double PHD fingers family 2	11	64857921	NM_006268	5977	11q13	Hs.13495	11	protein binding intracellular nucleus cytoplasm apoptosis zinc ion binding induction of apoptosis by extracellular signals regulation of transcription metal ion binding
225001_at	0.187	6.224	2.167	4.648e-02	0.313	-4.103	RAB3D	RAB3D, member RAS oncogene family	19	-11296092	AI744658	9545	19p13.2	Hs.655274	13	nucleotide binding GTPase activity protein binding GTP binding plasma membrane exocytosis small GTPase mediated signal transduction protein transport
212634_at	-0.427	6.841	-2.167	4.650e-02	0.313	-4.104	KIAA0776	KIAA0776	6	97076422	AW298092	23376	6q16.1	Hs.149367	8	protein binding
219711_at	-0.359	6.186	-2.167	4.650e-02	0.313	-4.104	ZNF586	zinc finger protein 586	19	62972836	NM_017652	54807	19q13.43	Hs.709730	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
201830_s_at	-0.439	6.960	-2.167	4.652e-02	0.313	-4.104	NET1	neuroepithelial cell transforming 1	10	5444517, 5478545	NM_005863	10276	10p15	Hs.25155	19	regulation of cell growth guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity cellular_component intracellular nucleus cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction
226058_at	0.232	5.513	2.166	4.656e-02	0.313	-4.105	B3GNT9	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	16	-65739505	AI651445	84752	16q22.1	Hs.718517	2	Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups
202160_at	-0.359	7.854	-2.166	4.656e-02	0.313	-4.105	CREBBP	CREB binding protein	16	-3715056	NM_004380	1387	16p13.3	Hs.459759	399	histone acetyltransferase complex response to hypoxia p53 binding transcription factor activity transcription coactivator activity transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent protein complex assembly signal transduction zinc ion binding acetyltransferase activity histone acetylation transferase activity N-terminal peptidyl-lysine acetylation homeostatic process interspecies interaction between organisms positive regulation of transcription positive regulation of transcription metal ion binding MyoD binding	Cell cycle Wnt signaling pathway Notch signaling pathway TGF-beta signaling pathway Adherens junction Jak-STAT signaling pathway Long-term potentiation Melanogenesis Huntington's disease Pathways in cancer Renal cell carcinoma Prostate cancer
219999_at	-0.260	6.195	-2.166	4.657e-02	0.313	-4.105	MAN2A2	mannosidase, alpha, class 2A, member 2	15	89248423	NM_018621	4122	15q26.1	Hs.116459	20	Golgi membrane alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process metabolic process zinc ion binding membrane integral to membrane carbohydrate binding metal ion binding	N-Glycan biosynthesis Metabolic pathways
205184_at	0.224	4.079	2.166	4.657e-02	0.313	-4.105	GNG4	guanine nucleotide binding protein (G protein), gamma 4	1	-233777607, -233777607	NM_004485	2786	1q42.3	Hs.159711	13	signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction regulation of G-protein coupled receptor protein signaling pathway hormone-mediated signaling negative regulation of cell growth	Chemokine signaling pathway
223440_at	-0.229	6.191	-2.166	4.659e-02	0.314	-4.105	C16orf70	chromosome 16 open reading frame 70	16	65701415	BC004556	80262	16q22.1	Hs.513666	7	protein binding
219670_at	0.412	5.782	2.166	4.661e-02	0.314	-4.106	BEND5	BEN domain containing 5	1	-48966126	NM_024603	79656	1p33	Hs.475348	5	Golgi apparatus
229364_at	0.219	5.156	2.166	4.662e-02	0.314	-4.106	LOC646870	hypothetical protein LOC646870	1		AI979338	646870	1q25.1
211175_at	0.149	5.555	2.166	4.662e-02	0.314	-4.106	GPR45	G protein-coupled receptor 45	2	105224631	U92642	11250	2q11.1-q12	Hs.590903	7	receptor activity G-protein coupled receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane
203711_s_at	-0.261	7.456	-2.166	4.663e-02	0.314	-4.106	HIBCH	3-hydroxyisobutyryl-Coenzyme A hydrolase	2	-190777604	NM_014362	26275	2q32.2	Hs.656685	8	3-hydroxyisobutyryl-CoA hydrolase activity protein binding mitochondrion metabolic process branched chain family amino acid catabolic process hydrolase activity	Valine, leucine and isoleucine degradation beta-Alanine metabolism Propanoate metabolism Metabolic pathways
233782_at	0.236	5.309	2.166	4.663e-02	0.314	-4.106	DCAF7	DDB1 and CUL4 associated factor 7	17	58981553	AU147133	10238	17q23.3	Hs.410596	11	protein binding cytoplasm
219555_s_at	-0.287	4.631	-2.165	4.665e-02	0.314	-4.106	CENPN	centromere protein N	16	79597603, 79597603, 79597603	NM_018455	55839	16q23.2	Hs.55028	9	chromosome, centromeric region condensed chromosome kinetochore nucleus chromosome
1557918_s_at	-0.199	5.117	-2.165	4.666e-02	0.314	-4.107	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	1	-113255992	AU131482	6566	1p12	Hs.75231	43	protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane
217227_x_at	0.186	5.527	2.165	4.667e-02	0.314	-4.107	IGL@	immunoglobulin lambda locus	22		X93006	3535	22q11.1-q11.2	Hs.449585 Hs.561078	20
232345_at	0.174	4.856	2.165	4.668e-02	0.314	-4.107	C18orf8	chromosome 18 open reading frame 8	18	19337459	AU158529	29919	18q11.2	Hs.464779	4
211087_x_at	-0.254	5.313	-2.165	4.672e-02	0.314	-4.108	MAPK14	mitogen-activated protein kinase 14	6	36103431, 36103431	Z25432	1432	6p21.3-p21.2	Hs.485233	561	DNA damage checkpoint nucleotide binding spindle pole angiogenesis chondrocyte differentiation protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase activity MAP kinase kinase activity protein binding ATP binding cell nucleus nucleoplasm cytoplasm cytosol glucose metabolic process protein amino acid phosphorylation cell motion chemotaxis response to stress protein kinase cascade Ras protein signal transduction skeletal muscle tissue development MP kinase activity transferase activity fatty acid oxidation lipopolysaccharide-mediated signaling pathway response to muramyl dipeptide response to lipopolysaccharide positive regulation of erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter	MAPK signaling pathway VEGF signaling pathway Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway Fc epsilon RI signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway GnRH signaling pathway Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection
226240_at	-0.264	7.145	-2.164	4.673e-02	0.314	-4.108	TADA2B	transcriptional adaptor 2 (ADA2 homolog, yeast)-beta	4	7096056	AI862537	93624	4p16.1	Hs.518614	4	DNA binding nucleus zinc ion binding regulation of transcription metal ion binding
212624_s_at	0.256	6.051	2.164	4.673e-02	0.314	-4.108	CHN1	chimerin (chimaerin) 1	2	-175372287	BF339445	1123	2q31.1	Hs.654534	21	SH3/SH2 adaptor activity GTPase activator activity protein binding intracellular intracellular signaling cascade zinc ion binding diacylglycerol binding metal ion binding
1553483_at	0.180	5.070	2.164	4.673e-02	0.314	-4.108	TSGA10IP	testis specific, 10 interacting protein	11	65469690	NM_152762	254187	11q13.1	Hs.350671	2
233656_s_at	-0.276	5.605	-2.164	4.675e-02	0.314	-4.108	VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)	2	-63973170	AL359939	51542	2p13-p14	Hs.48499	8	protein binding protein transport retrograde transport, endosome to Golgi
209716_at	0.227	6.491	2.164	4.675e-02	0.314	-4.108	CSF1	colony stimulating factor 1 (macrophage)	1	110254755, 110254755, 110254755	M37435	1435	1p21-p13	Hs.591402	123	positive regulation of cell-matrix adhesion reproductive developmental process cytokine activity macrophage colony stimulating factor receptor binding extracellular region extracellular space plasma membrane positive regulation of cell proliferation positive regulation of gene expression positive regulation of foam cell differentiation integral to membrane hemopoiesis cell differentiation positive regulation of cell migration positive regulation of cellular protein metabolic process positive regulation of mononuclear cell proliferation monocyte activation protein homodimerization activity receptor complex positive regulation of monocyte differentiation positive regulation of protein kinase activity perinuclear region of cytoplasm	Cytokine-cytokine receptor interaction Hematopoietic cell lineage
219714_s_at	0.486	5.935	2.164	4.675e-02	0.314	-4.108	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3	3	54131732	NM_018398	55799	3p21.1	Hs.656687	9	voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane	MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
213389_at	-0.255	6.844	-2.164	4.675e-02	0.314	-4.108	ZNF592	zinc finger protein 592	15	83092821	BF508616	9640	15q25.3	Hs.79347	7	DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
213897_s_at	0.291	8.690	2.164	4.681e-02	0.314	-4.109	MRPL23	mitochondrial ribosomal protein L23	11	1925077	AI832239	6150	11p15.5-p15.4	Hs.3254	11	nucleotide binding RNA binding structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation
236046_at	-0.450	5.952	-2.163	4.684e-02	0.314	-4.110	FLJ44896	FLJ44896 protein	5		AA781880	401166	5p15.33	Hs.711993
229664_at	-0.320	5.400	-2.163	4.686e-02	0.314	-4.110	MAPK8	mitogen-activated protein kinase 8	10	49279692	AI379407	5599	10q11.22	Hs.138211	387	nucleotide binding protein serine/threonine kinase activity JUN kinase activity MAP kinase activity protein binding ATP binding cytosol cell motion response to stress signal transduction JUN phosphorylation activation of pro-apoptotic gene products response to UV transferase activity negative regulation of apoptosis	MAPK signaling pathway ErbB signaling pathway Wnt signaling pathway Focal adhesion Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Pancreatic cancer
201117_s_at	0.394	7.175	2.163	4.686e-02	0.314	-4.110	CPE	carboxypeptidase E	4	166519546	NM_001873	1363	4q32.3	Hs.75360	39	metallocarboxypeptidase activity extracellular region plasma membrane protein modification process proteolysis neuropeptide signaling pathway metabolic process peptidase activity metallopeptidase activity zinc ion binding insulin processing metal ion binding	Type I diabetes mellitus
1559518_at	0.178	3.178	2.163	4.688e-02	0.314	-4.111	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12	11	43658718	BM460264	51144	11p11.2	Hs.132513	13	fibronectin binding estradiol 17-beta-dehydrogenase activity binding collagen binding endoplasmic reticulum steroid biosynthetic process heparin binding positive regulation of cell-substrate adhesion membrane integral to membrane oxidoreductase activity extracellular matrix organization extracellular matrix oxidation reduction	Androgen and estrogen metabolism Biosynthesis of unsaturated fatty acids Metabolic pathways
1556035_s_at	-0.258	7.248	-2.163	4.689e-02	0.314	-4.111	ZNF207	zinc finger protein 207	17	27701269	AI201248	7756	17q11.2	Hs.500775	7	transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
221828_s_at	-0.219	6.195	-2.163	4.689e-02	0.314	-4.111	FAM125B	family with sequence similarity 125, member B	9	128128948, 128128948	AK024432	89853	9q33.3	Hs.162659	4	endosome protein transport membrane	Endocytosis
220023_at	0.182	4.280	2.162	4.691e-02	0.314	-4.111	APOB48R	apolipoprotein B48 receptor	16	28413493	NM_018690	55911	16p11	Hs.200333	4	receptor activity plasma membrane lipid metabolic process triglyceride metabolic process lipid transport steroid metabolic process cholesterol metabolic process very-low-density lipoprotein receptor activity very-low-density lipoprotein particle low-density lipoprotein particle chylomicron
212987_at	-0.220	9.153	-2.162	4.692e-02	0.314	-4.111	FBXO9	F-box protein 9	6	53037754, 53038215, 53043729	AL031178	26268	6p12.3-p11.2	Hs.216653	9	ubiquitin ligase complex ubiquitin-protein ligase activity protein ubiquitination modification-dependent protein catabolic process
235997_at	0.156	6.430	2.162	4.693e-02	0.314	-4.112	ZNF74	zinc finger protein 74	22	19078479	AI554700	7625	22q11.2 22q11.21	Hs.517418	12	DNA binding RNA binding intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding metal ion binding
219088_s_at	-0.203	5.828	-2.162	4.696e-02	0.314	-4.112	ZNF576	zinc finger protein 576	19	48792383, 48792577	AA639585	79177	19q13.31	Hs.11110	5	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
211398_at	0.212	3.914	2.162	4.696e-02	0.314	-4.112	FGFR2	fibroblast growth factor receptor 2	10	-123231358, -123231358, -123227834, -123227834, -123227834, -123227834, -123227833	AB030075	2263	10q26	Hs.533683	232	nucleotide binding receptor activity fibroblast growth factor receptor activity protein binding ATP binding extracellular region plasma membrane plasma membrane protein amino acid phosphorylation heparin binding fibroblast growth factor receptor signaling pathway cell surface integral to membrane cell growth transferase activity	MAPK signaling pathway Endocytosis Regulation of actin cytoskeleton Pathways in cancer Prostate cancer
1554883_a_at	0.302	4.325	2.161	4.700e-02	0.315	-4.113	ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	5	-60205415	BC009793	1161	5q12.1	Hs.435237	24	nucleotide-excision repair complex protein polyubiquitination DNA helicase activity ubiquitin-protein ligase activity soluble fraction nucleus nucleoplasm transcription-coupled nucleotide-excision repair response to DNA damage stimulus response to oxidative stress response to oxidative stress DNA-dependent ATPase activity response to UV response to X-ray nuclear matrix protein complex binding regulation of transcription protein autoubiquitination	Nucleotide excision repair Ubiquitin mediated proteolysis
214183_s_at	0.496	4.083	2.161	4.705e-02	0.315	-4.114	TKTL1	transketolase-like 1	X	153177220, 153186602	X91817	8277	Xq28	Hs.102866	21	transketolase activity calcium ion binding nucleus cytoplasm glucose catabolic process thiamin metabolic process metabolic process transferase activity	Pentose phosphate pathway Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of plant hormones Metabolic pathways
1553086_at	-0.180	2.393	-2.161	4.705e-02	0.315	-4.114	C11orf40	chromosome 11 open reading frame 40	11	-4549228	NM_144663	143501	11p15.5	Hs.350556
216968_at	0.189	5.424	2.161	4.706e-02	0.315	-4.114	MASP2	mannan-binding lectin serine peptidase 2	1	-11027441, -11009166	Y18284	10747	1p36.3-p36.2	Hs.655645	51	complement activation, lectin pathway complement activation, lectin pathway serine-type endopeptidase activity calcium ion binding extracellular region extracellular region proteolysis complement activation, classical pathway peptidase activity calcium-dependent protein binding	Complement and coagulation cascades
201307_at	0.366	6.302	2.161	4.707e-02	0.315	-4.114	SEPT11	septin 11	4	78089918	AL534972	55752	4q21.1	Hs.128199	16	nucleotide binding stress fiber protein binding GTP binding cell cycle septin complex protein heterooligomerization cell division
224566_at	-0.535	10.652	-2.160	4.712e-02	0.315	-4.115	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AI042152	283131	11q13.1	Hs.523789 Hs.648467	6
223955_at	-0.220	4.139	-2.160	4.712e-02	0.315	-4.115	EFCAB4B	EF-hand calcium binding domain 4B	12	-3627369, -3619818, -3594754	BC004524	84766	12p13.32	Hs.504534 Hs.719531	6	calcium ion binding
224980_at	0.272	5.646	2.160	4.712e-02	0.315	-4.115	LEMD2	LEM domain containing 2	6	-33846968, -33846968	BF431373	221496	6p21.31	Hs.444845	4	nucleus integral to nuclear inner membrane membrane integral to membrane nuclear membrane
234995_at	0.186	3.243	2.160	4.714e-02	0.315	-4.116	CCDC52	coiled-coil domain containing 52	3	-114644254	AA668779	152185	3q13.2	Hs.477144	8
214751_at	0.430	4.058	2.160	4.715e-02	0.315	-4.116	ZNF468	zinc finger protein 468	19	-58033596	BE541042	90333	19q13.41	Hs.467223	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
204501_at	0.368	4.315	2.160	4.716e-02	0.315	-4.116	NOV	nephroblastoma overexpressed gene	8	120497732	NM_002514	4856	8q24.1	Hs.235935	40	regulation of cell growth insulin-like growth factor binding extracellular region growth factor activity
236703_at	-0.522	6.651	-2.160	4.716e-02	0.315	-4.116	NT5C2	5'-nucleotidase, cytosolic II	10	-104835929	BF114733	22978	10q24.32-q24.33	Hs.97439	12	nucleotide binding magnesium ion binding protein binding cytoplasm cytosol 5'-nucleotidase activity 5'-nucleotidase activity nucleotide metabolic process hydrolase activity	Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways
217421_at	0.192	5.266	2.160	4.717e-02	0.315	-4.116	PIWIL2	piwi-like 2 (Drosophila)	8	22188754, 22189024	AK000397	55124	8p21.3	Hs.661109	7	RNA 5'-end processing protein binding cytoplasm meiosis meiotic prophase I multicellular organismal development spermatogenesis cell differentiation germ-line stem cell maintenance gene silencing by RNA chromatoid body piRNA binding piRNA metabolic process DNA methylation during gametogenesis P granule positive regulation of translation oogenesis	Dorso-ventral axis formation
238655_at	0.173	4.991	2.159	4.720e-02	0.315	-4.117	ACAD10	acyl-Coenzyme A dehydrogenase family, member 10	12	110608239, 110608239	AL530994	80724	12q24.12	Hs.331141	6	acyl-CoA dehydrogenase activity metabolic process electron carrier activity hydrolase activity FAD binding
204581_at	0.244	4.315	2.159	4.721e-02	0.315	-4.117	CD22	CD22 molecule	19	40511918	NM_001771	933	19q13.1	Hs.579691	46	protein binding sugar binding plasma membrane cell adhesion integral to membrane	Cell adhesion molecules (CAMs) Hematopoietic cell lineage B cell receptor signaling pathway
205335_s_at	-0.182	8.585	-2.159	4.721e-02	0.315	-4.117	SRP19	signal recognition particle 19kDa	5	112224891	NM_003135	6728	5q21-q22	Hs.637001	14	nucleolus cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane 7S RNA binding response to drug	Protein export
230442_at	0.285	3.783	2.159	4.722e-02	0.315	-4.117	MTHFSD	methenyltetrahydrofolate synthetase domain containing	16	-85121283, -85121283, -85121282	AI700675	64779	16q24.1	Hs.343627	2	nucleotide binding RNA binding ATP binding folic acid and derivative biosynthetic process 5-formyltetrahydrofolate cyclo-ligase activity
202852_s_at	-0.231	5.190	-2.159	4.723e-02	0.315	-4.117	AAGAB	alpha- and gamma-adaptin binding protein	15	-65280420	NM_024666	79719	15q22.33-q23	Hs.254642	12	cytoplasm protein transport
212148_at	-0.328	8.342	-2.159	4.726e-02	0.316	-4.118	PBX1	pre-B-cell leukemia homeobox 1	1	162795425	AL049381	5087	1q23	Hs.557097	56	transcription factor activity protein binding nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent C21-steroid hormone biosynthetic process sex determination cell differentiation sequence-specific DNA binding
235566_at	-0.349	4.567	-2.158	4.728e-02	0.316	-4.118	TMF1	TATA element modulatory factor 1	3	-69151667	AW591660	7110	3p21-p12	Hs.267632	15	Golgi membrane DNA binding RNA polymerase II transcription factor activity transcription cofactor activity protein binding nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter membrane
208561_at	-0.343	4.362	-2.158	4.729e-02	0.316	-4.118	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	12	-21849374, -21841590	NM_020297	10060	12p12.1	Hs.446050	35	nucleotide binding receptor activity transporter activity ATP binding transport sulfonylurea receptor activity ATP-sensitive potassium channel complex potassium ion import potassium channel regulator activity membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances defense response to virus	ABC transporters
205084_at	-0.394	5.876	-2.158	4.729e-02	0.316	-4.118	BCAP29	B-cell receptor-associated protein 29	7	107007657, 107008439	NM_018844	55973	7q22-q31	Hs.303787	12	endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport
232289_at	-0.557	8.438	-2.158	4.730e-02	0.316	-4.118	KCNJ12	potassium inwardly-rectifying channel, subfamily J, member 12	17	21220291	BF237871	3768	17p11.2	Hs.200629	24	inward rectifier potassium channel activity voltage-gated ion channel activity protein binding ion transport potassium ion transport muscle contraction blood circulation regulation of heart contraction ion channel inhibitor activity potassium channel regulator activity membrane integral to membrane PDZ domain binding T-tubule dendrite potassium ion binding cell soma
226434_at	0.236	6.539	2.158	4.730e-02	0.316	-4.118	C7orf47	chromosome 7 open reading frame 47	7	-99870847	BF000655	221908	7q22.1	Hs.413359	3
222588_s_at	-0.235	6.003	-2.158	4.730e-02	0.316	-4.118	C11orf57	chromosome 11 open reading frame 57	11	111450177	AA024582	55216	11q23.1	Hs.195060	6
201387_s_at	0.736	7.216	2.158	4.732e-02	0.316	-4.119	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	4	40953654	NM_004181	7345	4p14	Hs.518731	94	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding intracellular nucleus nucleolus cytoplasm cytoplasm cytosol ubiquitin-dependent protein catabolic process response to stress axon target recognition adult walking behavior peptidase activity omega peptidase activity cell proliferation protein deubiquitination ligase activity axon transport of mitochondrion axon eating behavior cell soma ubiquitin binding neuromuscular process	Parkinson's disease
207191_s_at	0.395	5.209	2.158	4.733e-02	0.316	-4.119	ISLR	immunoglobulin superfamily containing leucine-rich repeat	15	72253139, 72253957	NM_005545	3671	15q23-q24	Hs.699822 Hs.710506	6	protein binding extracellular region cell adhesion
235552_at	-0.188	6.379	-2.158	4.734e-02	0.316	-4.119	METTL14	methyltransferase like 14	4	119826021	AA354181	57721	4q26	Hs.657806	3	RNA methylation nucleus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process methyltransferase activity mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity transferase activity
227207_x_at	-0.217	6.302	-2.158	4.734e-02	0.316	-4.119	ZNF213	zinc finger protein 213	16	3125057, 3125134	BF510572	7760	16p13.3	Hs.115284	7	transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208523_x_at	0.206	4.866	2.158	4.734e-02	0.316	-4.119	HIST1H2BI	histone cluster 1, H2bi	6	26381182	NM_003525	8346	6p21.3	Hs.553506	8		Systemic lupus erythematosus
231285_at	0.387	4.497	2.157	4.735e-02	0.316	-4.119	STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	3	31549494	AI458583	201595	3p23	Hs.475812	9	dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum protein amino acid glycosylation membrane integral to membrane transferase activity	N-Glycan biosynthesis Metabolic pathways
244844_at	-0.171	3.496	-2.157	4.737e-02	0.316	-4.120	MRS2	MRS2 magnesium homeostasis factor homolog (S. cerevisiae)	6	24511131	AI224894	57380	6p22.3-p22.1	Hs.719256	9	magnesium ion binding mitochondrion mitochondrial inner membrane ion transport membrane integral to membrane metal ion transport metal ion transmembrane transporter activity
213364_s_at	0.321	6.728	2.157	4.738e-02	0.316	-4.120	SNX1	sorting nexin 1	15	62175229	AI052536	6642	15q22.31	Hs.188634	28	protein binding cytoplasm endosome Golgi apparatus intracellular protein transport endocytosis cell communication protein transporter activity membrane phosphoinositide binding
214780_s_at	0.195	6.034	2.157	4.740e-02	0.316	-4.120	MYO9B	myosin IXB	19	17047590	AK002201	4650	19p13.1	Hs.123198	36	microfilament motor activity microfilament motor activity nucleotide binding actin binding GTPase activator activity Rho GTPase activator activity calmodulin binding ATP binding intracellular cytoplasm cell cortex intracellular signaling cascade zinc ion binding myosin complex ATPase activity diacylglycerol binding actin filament-based movement filamentous actin ARF protein signal transduction protein homodimerization activity ADP binding metal ion binding perinuclear region of cytoplasm
204674_at	0.216	6.129	2.157	4.740e-02	0.316	-4.120	LRMP	lymphoid-restricted membrane protein	12	25096507	NM_006152	4033	12p12.1	Hs.124922	9	cytoplasm endoplasmic reticulum endoplasmic reticulum membrane integral to plasma membrane vesicle targeting vesicle fusion membrane
230129_at	-0.315	5.099	-2.157	4.741e-02	0.316	-4.121	PSTK	phosphoseryl-tRNA kinase	10	124729545	BF589448	118672	10q26.13	Hs.281004	4	nucleotide binding magnesium ion binding ATP binding translation kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor	Aminoacyl-tRNA biosynthesis
235773_at	0.244	3.718	2.157	4.743e-02	0.316	-4.121	ZIK1	zinc finger protein interacting with K protein 1 homolog (mouse)	19	62787439	AW029293	284307	19q13.43	Hs.454830	3	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
228497_at	0.253	3.684	2.156	4.745e-02	0.316	-4.121	SLC22A15	solute carrier family 22, member 15	1	116320641	AI279062	55356	1p13.1	Hs.125482	4	transporter activity ion transport membrane integral to membrane
214968_at	0.188	4.268	2.156	4.747e-02	0.316	-4.122	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51	12	-131187092	AV694312	317781	12q24.33	Hs.445168	6	nucleotide binding RNA binding helicase activity ATP binding nucleus nucleolus rRNA processing ATP-dependent helicase activity hydrolase activity
1560062_at	0.175	4.717	2.156	4.748e-02	0.316	-4.122	SLC29A2	solute carrier family 29 (nucleoside transporters), member 2	11	-65886567	BM709337	3177	11q13	Hs.569017	26	nucleoside transmembrane transporter activity nucleus nucleolus plasma membrane integral to plasma membrane nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transport cell proliferation nucleoside transport
226714_at	0.194	6.773	2.156	4.750e-02	0.316	-4.122	SAMD4B	sterile alpha motif domain containing 4B	19	44524947	AA149818	55095	19q13.2	Hs.612332	8	protein binding
214151_s_at	-0.278	7.368	-2.156	4.752e-02	0.316	-4.122	CCPG1	cell cycle progression 1	15	-53434729, -53434729	AU144243	9236	15q21.1	Hs.285051	5	cell cycle membrane integral to membrane
40837_at	-0.244	7.472	-2.155	4.754e-02	0.316	-4.123	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	19	-2948636, -2948636, -2948636	M99436	7089	19p13.3	Hs.332173	15	protein binding nucleus signal transduction organ morphogenesis Wnt receptor signaling pathway regulation of transcription
206694_at	0.220	4.956	2.155	4.754e-02	0.316	-4.123	PNLIPRP1	pancreatic lipase-related protein 1	10	118340479	NM_006229	5407	10q25.3	Hs.73923	3	triacylglycerol lipase activity extracellular region lipid catabolic process hydrolase activity	Glycerolipid metabolism Metabolic pathways
1559052_s_at	0.306	4.180	2.155	4.756e-02	0.316	-4.123	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	3	197951124	U25975	5062	3q29	Hs.518530	80	nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol negative regulation of protein kinase activity apoptosis signal transduction membrane transferase activity regulation of growth identical protein binding interspecies interaction between organisms protein amino acid autophosphorylation perinuclear region of cytoplasm	MAPK signaling pathway ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
210066_s_at	-0.600	3.326	-2.155	4.757e-02	0.316	-4.123	AQP4	aquaporin 4	18	-22686004, -22686004	D63412	361	18q11.2-q12.1	Hs.315369	60	transporter activity water transporter activity integral to plasma membrane transport nervous system development excretion membrane
228219_s_at	0.279	6.969	2.155	4.757e-02	0.316	-4.123	UPB1	ureidopropionase, beta	22	23221250	AI770035	51733	22q11.2	Hs.474388	10	beta-ureidopropionase activity beta-ureidopropionase activity cytoplasm cytosol nitrogen compound metabolic process zinc ion binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds metal ion binding	Pyrimidine metabolism beta-Alanine metabolism Pantothenate and CoA biosynthesis Drug metabolism - other enzymes Metabolic pathways
227566_at	0.185	3.580	2.155	4.759e-02	0.316	-4.124	NTM	neurotrimin	11	130745580, 131285921, 131285921, 131285921	AW085558	50863	11q25	Hs.504352	9	protein binding plasma membrane cell adhesion neuron recognition anchored to membrane
238022_at	-0.856	4.898	-2.155	4.760e-02	0.316	-4.124	CRNDE	colorectal neoplasia differentially expressed (non-protein coding)	16		AA954994	643911	16q12.2	Hs.237396	1
225140_at	-0.252	3.678	-2.155	4.760e-02	0.316	-4.124	KLF3	Kruppel-like factor 3 (basic)	4	38342184	BF438116	51274	4p14	Hs.298658	12	transcription factor activity intracellular nucleus multicellular organismal development zinc ion binding regulation of transcription metal ion binding
1553583_a_at	0.298	5.731	2.155	4.761e-02	0.316	-4.124	THRSP	thyroid hormone responsive (SPOT14 homolog, rat)	11	77452554	NM_003251	7069	11q13.5	Hs.591969	12	protein binding nucleus lipid metabolic process
201006_at	0.209	6.091	2.154	4.763e-02	0.316	-4.125	PRDX2	peroxiredoxin 2	19	-12772426, -12768633	NM_005809	7001	19p13.2	Hs.432121	52	cytoplasm anti-apoptosis response to oxidative stress response to oxidative stress thioredoxin peroxidase activity oxidoreductase activity regulation of apoptosis cell redox homeostasis oxidation reduction
220954_s_at	-0.354	6.362	-2.154	4.766e-02	0.317	-4.125	PILRB	paired immunoglobin-like type 2 receptor beta	7	99771672, 99793561	NM_013440	29990	7q22.1	Hs.632314	10	receptor activity protein binding integral to plasma membrane activation of transmembrane receptor protein tyrosine kinase activity membrane
206464_at	0.281	4.353	2.154	4.767e-02	0.317	-4.125	BMX	BMX non-receptor tyrosine kinase	X	15428820, 15435351	NM_001721	660	Xp22.2	Hs.495731	37	nucleotide binding non-membrane spanning protein tyrosine kinase activity signal transducer activity protein binding ATP binding cytoplasm centrosome protein amino acid phosphorylation intracellular signaling cascade mesoderm development zinc ion binding transferase activity metal ion binding
239569_at	0.233	5.085	2.154	4.768e-02	0.317	-4.125	FLJ31485	hypothetical protein LOC440119	12		AI803208	440119	12q24.33	Hs.288262	1
215844_at	0.308	5.975	2.154	4.770e-02	0.317	-4.126	TNPO2	transportin 2	19	-12671008, -12671008, -12671008	AK022217	30000	19p13.2	Hs.416049 Hs.714402	13	protein import into nucleus, docking protein binding nucleus nuclear pore cytoplasm intracellular protein transport nuclear localization sequence binding protein transporter activity
1567271_at	0.192	3.203	2.154	4.771e-02	0.317	-4.126	OR4C1P	olfactory receptor, family 4, subfamily C, member 1 pseudogene	11		X64985	26242	11q11	Hs.550274	1
238532_at	-0.336	6.974	-2.153	4.772e-02	0.317	-4.126	DPF3	D4, zinc and double PHD fingers, family 3	14	-72206412	AI125562	8110	14q24.3-q31.1	Hs.162868	9	protein binding intracellular nucleus biological_process zinc ion binding chromatin modification regulation of transcription metal ion binding
203372_s_at	0.307	4.033	2.153	4.773e-02	0.317	-4.126	SOCS2	suppressor of cytokine signaling 2	12	92487728	AB004903	8835	12q	Hs.485572	40	regulation of cell growth SH3/SH2 adaptor activity growth hormone receptor binding prolactin receptor binding insulin-like growth factor receptor binding protein binding cytoplasm anti-apoptosis intracellular signaling cascade JAK-STAT cascade JAK pathway signal transduction adaptor activity negative regulation of signal transduction modification-dependent protein catabolic process response to estradiol stimulus growth hormone receptor signaling pathway	Jak-STAT signaling pathway Insulin signaling pathway Type II diabetes mellitus
215326_at	0.224	4.261	2.153	4.773e-02	0.317	-4.126	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	19	44308259	AB032968	10298	19q13.2	Hs.20447	32	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding Golgi apparatus protein amino acid phosphorylation cell motion signal transduction transferase activity	ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma
201526_at	0.259	8.215	2.153	4.779e-02	0.317	-4.128	ARF5	ADP-ribosylation factor 5	7	127015752	NM_001662	381	7q31.3	Hs.653202	18	nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport
206208_at	0.270	6.232	2.152	4.782e-02	0.317	-4.128	CA4	carbonic anhydrase IV	17	55582083	NM_000717	762	17q23	Hs.89485	30	carbonate dehydratase activity membrane fraction plasma membrane one-carbon metabolic process visual perception zinc ion binding lyase activity anchored to membrane metal ion binding response to stimulus	Nitrogen metabolism
220388_at	0.220	4.128	2.152	4.783e-02	0.317	-4.128	FER1L4	fer-1-like 4 (C. elegans)	20	-33609920	NM_024777	80307	20q11.22	Hs.72222	7	membrane integral to membrane
238046_x_at	0.244	5.057	2.152	4.786e-02	0.317	-4.129	PWWP2B	PWWP domain containing 2B	10	134060691	AI800015	170394	10q26.3	Hs.527751	5
242600_at	-0.465	8.354	-2.152	4.787e-02	0.317	-4.129	FRMD3	FERM domain containing 3	9	-85052126	AA746863	257019	9q21.32	Hs.709357	7	binding cytoplasm cytoskeleton cytoskeletal protein binding membrane integral to membrane extrinsic to membrane
200907_s_at	-0.519	9.408	-2.152	4.789e-02	0.318	-4.129	PALLD	palladin, cytoskeletal associated protein	4	169654791	AU157932	23022	4q32.3	Hs.151220	40	actin binding protein binding nucleus cytoplasm cytoskeleton actin filament cytoskeleton organization muscle alpha-actinin binding
209018_s_at	-0.232	9.533	-2.151	4.791e-02	0.318	-4.130	PINK1	PTEN induced putative kinase 1	1	20832534	BF432478	65018	1p36	Hs.389171	105	nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding mitochondrion mitochondrial outer membrane protein amino acid phosphorylation response to stress protein kinase cascade membrane integral to membrane transferase activity positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion	Parkinson's disease
222449_at	-0.382	7.197	-2.151	4.792e-02	0.318	-4.130	PMEPA1	prostate transmembrane protein, androgen induced 1	20	-55656857, -55656857, -55656857	AL035541	56937	20q13.31 20q13.31-q13.33	Hs.517155	12	molecular_function plasma membrane integral to membrane androgen receptor signaling pathway WW domain binding
207391_s_at	0.196	6.953	2.151	4.792e-02	0.318	-4.130	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	1	149437644	NM_003557	8394	1q22-q24	Hs.655131 Hs.707569	20	nucleotide binding ATP binding cellular_component Golgi apparatus Golgi stack plasma membrane glycerophospholipid metabolic process signal transduction kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity phosphorylation transferase activity phosphatidylinositol metabolic process	Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system Endocytosis Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton
1560833_at	-0.236	3.549	-2.151	4.793e-02	0.318	-4.130	LOC643648	hypothetical protein LOC643648	9		BG189393	643648	9p11.2	Hs.640178	1
218073_s_at	-0.344	3.461	-2.151	4.793e-02	0.318	-4.130	TMEM48	transmembrane protein 48	1	-54005975	NM_018087	55706	1p32.3	Hs.476525	10	nucleus nuclear pore protein transport membrane integral to membrane structural constituent of nuclear pore nuclear pore distribution mRNA transport nuclear pore complex assembly intracellular protein transmembrane transport
218477_at	0.335	6.246	2.151	4.794e-02	0.318	-4.130	TMEM14A	transmembrane protein 14A	6	52643842	NM_014051	28978	6p12.2	Hs.94896	3	membrane integral to membrane
1557073_s_at	-0.298	5.441	-2.151	4.795e-02	0.318	-4.130	TTBK2	tau tubulin kinase 2	15	-40823835	AK074481	146057	15q15.2	Hs.659846 Hs.713940	12	nucleotide binding protein serine/threonine kinase activity ATP binding cell death transferase activity peptidyl-serine phosphorylation
208542_x_at	0.179	2.328	2.151	4.796e-02	0.318	-4.131	ZNF208	zinc finger protein 208	19	-21940736	NM_007153	7757	19p12	Hs.541334	5	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
208734_x_at	-0.381	8.298	-2.151	4.798e-02	0.318	-4.131	RAB2A	RAB2A, member RAS oncogene family	8	61592112	M28213	5862	8q12.1	Hs.369017	19	nucleotide binding GTPase activity GTP binding endoplasmic reticulum Golgi apparatus ER to Golgi vesicle-mediated transport small GTPase mediated signal transduction protein transport membrane vesicle-mediated transport melanosome
201435_s_at	-0.446	8.273	-2.151	4.798e-02	0.318	-4.131	EIF4E	eukaryotic translation initiation factor 4E	4	-100018629, -100018629	AW268640	1977	4q21-q25	Hs.249718	143	RNA cap binding translation initiation factor activity protein binding cytoplasm cytosol translational initiation regulation of translation eukaryotic translation initiation factor 4F complex interspecies interaction between organisms	mTOR signaling pathway Insulin signaling pathway
211536_x_at	-0.196	5.661	-2.150	4.799e-02	0.318	-4.131	MAP3K7	mitogen-activated protein kinase kinase kinase 7	6	-91282073, -91282073	AB009358	6885	6q16.1-q16.3	Hs.719192	114	nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation	MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway
207352_s_at	-0.247	4.057	-2.150	4.799e-02	0.318	-4.131	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	5	-160648013	NM_021911	2561	5q34	Hs.303527	47	GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport gamma-aminobutyric acid signaling pathway synaptic transmission cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane	Neuroactive ligand-receptor interaction
218051_s_at	0.224	4.996	2.150	4.800e-02	0.318	-4.131	NT5DC2	5'-nucleotidase domain containing 2	3	-52533424, -52533424	NM_022908	64943	3p21.1	Hs.84753	7	magnesium ion binding hydrolase activity
201352_at	-0.180	10.474	-2.150	4.801e-02	0.318	-4.132	YME1L1	YME1-like 1 (S. cerevisiae)	10	-27439388	NM_014263	10730	10p14	Hs.499145 Hs.74647	9	nucleotide binding metalloendopeptidase activity ATP binding mitochondrion proteolysis peptidase activity zinc ion binding membrane nucleoside-triphosphatase activity metal ion binding
223679_at	0.202	5.410	2.150	4.804e-02	0.318	-4.132	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	3	41215945	AF130085	1499	3p21	Hs.476018	680	negative regulation of transcription from RNA polymerase II promoter skeletal system development patterning of blood vessels gastrulation with mouth forming second endoderm formation cell fate specification endodermal cell fate commitment epithelial to mesenchymal transition chromatin binding double-stranded DNA binding transcription factor activity transcription coactivator activity signal transducer activity membrane fraction nucleus transcription factor complex cytoplasm centrosome cytosol cytoskeleton plasma membrane fascia adherens apoptosis cell-matrix adhesion synaptic transmission ectoderm development glial cell fate determination heart development protein C-terminus binding transcription factor binding anterior/posterior axis specification dorsal/ventral axis specification proximal/distal pattern formation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process basolateral plasma membrane lateral plasma membrane morphogenesis of embryonic epithelium cell-cell adhesion catenin complex kinase binding protein phosphatase binding Z disc lamellipodium hemopoiesis lung development androgen receptor signaling pathway positive regulation of epithelial cell differentiation beta-catenin destruction complex forebrain development regulation of centriole-centriole cohesion pancreas development microvillus membrane negative regulation of chondrocyte differentiation T cell differentiation in the thymus cellular protein localization Axin-APC-beta-catenin-GSK3B complex embryonic hindlimb morphogenesis embryonic arm morphogenesis regulation of cell proliferation odontogenesis of dentine-containing tooth embryonic digit morphogenesis apical junction complex positive regulation of MAPKKK cascade apical part of cell alpha-catenin binding cadherin binding bone resorption positive regulation of osteoblast differentiation negative regulation of osteoclast differentiation cell maturation synaptic vesicle transport thymus development camera-type eye morphogenesis androgen receptor binding synapse organization Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex I-SMAD binding	Wnt signaling pathway Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Melanogenesis Pathogenic Escherichia coli infection - EHEC Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Arrhythmogenic right ventricular cardiomyopathy (ARVC)
208945_s_at	-0.304	8.493	-2.150	4.806e-02	0.318	-4.132	BECN1	beclin 1, autophagy related	17	-38215675	NM_003766	8678	17q21	Hs.716464	56	protein binding cytoplasm Golgi apparatus trans-Golgi network autophagy anti-apoptosis cellular defense response negative regulation of cell proliferation response to virus membrane cytoplasmic membrane-bounded vesicle positive regulation of macroautophagy protein complex	Regulation of autophagy
201711_x_at	-0.305	6.362	-2.150	4.806e-02	0.318	-4.132	RANBP2	RAN binding protein 2	2	108702368	AI681120	5903	2q12.3	Hs.199561 Hs.715056	61	peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport
219253_at	-0.350	5.031	-2.150	4.807e-02	0.318	-4.133	TMEM185B	transmembrane protein 185B (pseudogene)	2	-120695323	NM_024121	79134	2q14.2	Hs.376722	5	membrane integral to membrane
205130_at	0.212	4.763	2.150	4.807e-02	0.318	-4.133	RAGE	renal tumor antigen	14	-101764930	NM_014226	5891	14q32	Hs.104119	67	nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation signal transduction transferase activity
205216_s_at	-0.184	4.469	-2.149	4.809e-02	0.318	-4.133	APOH	apolipoprotein H (beta-2-glycoprotein I)	17	-61638608	NM_000042	350	17q23-qter	Hs.445358	129	negative regulation of endothelial cell proliferation glycoprotein binding phospholipid binding extracellular region extracellular space triglyceride metabolic process blood coagulation, intrinsic pathway heparin binding cell surface negative regulation of endothelial cell migration negative regulation of angiogenesis positive regulation of blood coagulation negative regulation of blood coagulation organ regeneration plasminogen activation negative regulation of myeloid cell apoptosis triglyceride transport very-low-density lipoprotein particle high-density lipoprotein particle negative regulation of smooth muscle cell apoptosis chylomicron eukaryotic cell surface binding positive regulation of lipoprotein lipase activity negative regulation of fibrinolysis lipoprotein lipase activator activity
214133_at	0.230	5.952	2.149	4.809e-02	0.318	-4.133	MUC6	mucin 6, oligomeric mucus/gel-forming	11	-1002823	AI611214	4588	11p15.5-p15.4	Hs.528432	26	extracellular matrix structural constituent extracellular region maintenance of gastrointestinal epithelium
227436_at	-0.336	7.090	-2.149	4.809e-02	0.318	-4.133	OTUD7B	OTU domain containing 7B	1	-148178855	BG291552	56957	1q21.2	Hs.98322	11	DNA binding ubiquitin thiolesterase activity protein binding nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding protein deubiquitination modification-dependent protein catabolic process negative regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding
1562442_a_at	-0.194	5.114	-2.149	4.810e-02	0.318	-4.133	SSBP1	single-stranded DNA binding protein 1	7	141084644	BC008402	6742	7q34	Hs.490394	21	DNA binding single-stranded DNA binding mitochondrion DNA replication mitochondrial nucleoid positive regulation of helicase activity	DNA replication Mismatch repair Homologous recombination
202306_at	0.296	8.317	2.149	4.811e-02	0.318	-4.133	POLR2G	polymerase (RNA) II (DNA directed) polypeptide G	11	62285586	NM_002696	5436	11q13.1	Hs.14839	86	nuclear mRNA splicing, via spliceosome RNA binding DNA-directed RNA polymerase activity protein binding nucleus nucleoplasm transcription transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter	Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease
221781_s_at	-0.280	3.074	-2.149	4.813e-02	0.318	-4.134	DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	2	183289243	BG168666	54431	2q32.1	Hs.516632	13	extracellular region endoplasmic reticulum endoplasmic reticulum lumen protein folding heat shock protein binding cell redox homeostasis unfolded protein binding
215509_s_at	0.162	3.692	2.149	4.814e-02	0.318	-4.134	BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	2	-111111882	AL137654	699	2q14	Hs.469649	55	nucleotide binding condensed chromosome kinetochore condensed nuclear chromosome, centromeric region protein serine/threonine kinase activity ATP binding nucleus spindle pole body protein amino acid phosphorylation cell cycle mitosis mitotic cell cycle spindle assembly checkpoint cell proliferation transferase activity cell division	Cell cycle
240396_at	0.230	4.626	2.149	4.817e-02	0.318	-4.134	IL20RA	interleukin 20 receptor, alpha	6	-137362800	AI686661	53832	6q22.33-q23.1	Hs.445868	15	receptor activity cytokine receptor activity membrane integral to membrane	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway
204152_s_at	0.194	4.888	2.149	4.817e-02	0.318	-4.134	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	22	-36195048	AI738965	4242	22q12	Hs.517603	15	extracellular space Golgi apparatus pattern specification process membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Notch signaling pathway
208883_at	-0.384	6.168	-2.148	4.820e-02	0.318	-4.135	UBR5	ubiquitin protein ligase E3 component n-recognin 5	8	-103334744	BF515424	51366	8q22	Hs.591856	21	RNA binding ubiquitin-protein ligase activity protein binding intracellular soluble fraction nucleus protein modification process ubiquitin-dependent protein catabolic process response to DNA damage stimulus zinc ion binding cell proliferation ligase activity acid-amino acid ligase activity metal ion binding progesterone receptor signaling pathway	Ubiquitin mediated proteolysis
200896_x_at	-0.213	9.699	-2.148	4.820e-02	0.318	-4.135	HDGF	hepatoma-derived growth factor (high-mobility group protein 1-like)	1	-154978522, -154978522, -154978522	NM_004494	3068	1q21-q23	Hs.506748	22	nucleotide binding DNA binding extracellular space nucleus cytoplasm signal transduction growth factor activity heparin binding cell proliferation regulation of transcription
219766_at	0.219	5.297	2.148	4.821e-02	0.318	-4.135	B9D2	B9 protein domain 2	19	-46552161	NM_030578	80776	19q13.2	Hs.567596	7	nucleus cilium microtubule basal body cell projection organization cilium axoneme
40020_at	0.204	4.436	2.148	4.821e-02	0.318	-4.135	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	3	-48648899	AB011536	1951	3p24.1-p21.2	Hs.631926	10	G-protein coupled receptor activity G-protein coupled receptor activity calcium ion binding protein binding plasma membrane homophilic cell adhesion neuropeptide signaling pathway multicellular organismal development integral to membrane integral to membrane
44673_at	0.178	6.216	2.148	4.823e-02	0.318	-4.136	SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	20	-3615616	N53555	6614	20p13	Hs.31869	13	protein binding sugar binding extracellular region plasma membrane inflammatory response cell-matrix adhesion integral to membrane cell-cell adhesion	Cell adhesion molecules (CAMs)
223053_x_at	-0.212	8.527	-2.147	4.829e-02	0.319	-4.137	SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	1	-1466915	AF277178	29101	1p36.33	Hs.30026 Hs.657061	7	phosphoprotein phosphatase activity nucleus cytoplasm mRNA processing hydrolase activity
203630_s_at	-0.277	6.525	-2.147	4.830e-02	0.319	-4.137	COG5	component of oligomeric golgi complex 5	7	-106635533, -106629424	NM_006348	10466	7q22-q31	Hs.239631 Hs.658093 Hs.97627	13	molecular_function protein binding cytoplasm Golgi apparatus cytosol intra-Golgi vesicle-mediated transport protein transport membrane Golgi transport complex Golgi transport complex
212793_at	-0.540	7.080	-2.147	4.834e-02	0.319	-4.137	DAAM2	dishevelled associated activator of morphogenesis 2	6	39868770	BF513244	23500	6p21.2	Hs.357128	7	actin binding cellular component organization Rho GTPase binding actin cytoskeleton organization	Wnt signaling pathway
227468_at	0.220	4.630	2.147	4.834e-02	0.319	-4.138	CPT1C	carnitine palmitoyltransferase 1C	19	54886212, 54886218	AL565745	126129	19q13.33	Hs.112195	8	carnitine O-palmitoyltransferase activity mitochondrion mitochondrial outer membrane lipid metabolic process fatty acid metabolic process acyltransferase activity membrane integral to membrane transferase activity	Fatty acid metabolism PPAR signaling pathway Adipocytokine signaling pathway
229466_at	0.187	5.339	2.147	4.834e-02	0.319	-4.138	TRIM66	tripartite motif-containing 66	11	-8590161	AU144187	9866	11p15.4	Hs.130836	4	protein binding intracellular nucleus zinc ion binding chromocenter transcription repressor activity protein homodimerization activity negative regulation of transcription, DNA-dependent metal ion binding
204719_at	0.455	7.988	2.147	4.835e-02	0.319	-4.138	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	17	-64375025	NM_007168	10351	17q24	Hs.58351	9	nucleotide binding ATP binding plasma membrane transport integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters
231820_x_at	0.246	4.918	2.147	4.835e-02	0.319	-4.138	ZNF587	zinc finger protein 587	19	63053080	BF038484	84914	19q13.43	Hs.642598 Hs.715493	6	DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding
1570308_at	0.166	2.725	2.146	4.837e-02	0.319	-4.138	LOC100131298	PRO1095	22		AF130053	100131298	22q13.2	Hs.621363
1553559_at	0.294	4.421	2.146	4.840e-02	0.319	-4.139	TMEM171	transmembrane protein 171	5	72452143	NM_173490	134285	5q13.2	Hs.162246	5	membrane integral to membrane
219049_at	0.257	5.376	2.146	4.841e-02	0.319	-4.139	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	8	-19305951, -19305951, -19305951	NM_018371	55790	8p21.3	Hs.613729 Hs.655166	10	intracellular soluble fraction Golgi apparatus nervous system development cell recognition cell proliferation peptidoglycan glycosyltransferase activity anatomical structure morphogenesis heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process glucuronosyltransferase activity membrane integral to membrane transferase activity UDP-N-acetylgalactosamine metabolic process integral to Golgi membrane extracellular matrix organization chondroitin sulfate biosynthetic process heparin biosynthetic process Golgi cisterna membrane UDP-glucuronate metabolic process metal ion binding glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity dermatan sulfate proteoglycan biosynthetic process chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	Chondroitin sulfate biosynthesis Metabolic pathways
234633_at	-0.217	3.013	-2.146	4.842e-02	0.319	-4.139	KRTAP4-11	keratin associated protein 4-11	17	-36526961, 234615	AJ406944	653240	17q21.2	Hs.307015 Hs.719695 Hs.719855	5	keratin filament
231686_at	-0.244	3.759	-2.146	4.842e-02	0.319	-4.139	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	15	-43440613	AV649811	2628	15q21.1	Hs.75335	23	cytoplasm mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine biosynthetic process response to oxidative stress response to nutrient embryonic development response to organic substance glycine amidinotransferase activity membrane transferase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines tissue regeneration response to peptide hormone stimulus response to mercury ion	Glycine, serine and threonine metabolism Arginine and proline metabolism Metabolic pathways
218831_s_at	0.278	7.460	2.146	4.842e-02	0.319	-4.139	FCGRT	Fc fragment of IgG, receptor, transporter, alpha	19	54707347, 54708247	NM_004107	2217	19q13.3	Hs.111903	48	receptor activity plasma membrane immune response female pregnancy integral to membrane IgG binding antigen processing and presentation MHC class I protein complex
209678_s_at	-0.278	6.378	-2.146	4.843e-02	0.319	-4.139	PRKCI	protein kinase C, iota	3	171422913	L18964	5584	3q26.3	Hs.478199	91	polarisome nucleotide binding protein kinase C activity protein binding ATP binding phospholipid binding nucleus cytoplasm endosome cytosol protein amino acid phosphorylation protein targeting to membrane cytoskeleton organization actin filament organization intracellular signaling cascade zinc ion binding membrane membrane organization vesicle-mediated transport apical plasma membrane transferase activity diacylglycerol binding cellular response to insulin stimulus establishment of apical/basal cell polarity eye photoreceptor cell development establishment or maintenance of epithelial cell apical/basal polarity cell-cell junction organization positive regulation of glucose import metal ion binding secretion Golgi vesicle budding regulation of establishment of protein localization	Endocytosis Tight junction Insulin signaling pathway
201168_x_at	0.199	7.046	2.146	4.844e-02	0.319	-4.139	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	17	-77418885	NM_004309	396	17q25.3	Hs.159161	38	Rho GDP-dissociation inhibitor activity GTPase activator activity cytoplasm cytoskeleton anti-apoptosis cell motion negative regulation of cell adhesion Rho protein signal transduction identical protein binding	Neurotrophin signaling pathway
212592_at	0.705	2.643	2.145	4.845e-02	0.319	-4.139	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	4	-71740121	AV733266	3512	4q21	Hs.643431 Hs.715953	24	antigen binding extracellular region immune response
229800_at	1.650	6.111	2.145	4.847e-02	0.319	-4.140	DCLK1	doublecortin-like kinase 1	13	-35241122	AI129626	9201	13q13	Hs.507755 Hs.717124	15	nucleotide binding protein serine/threonine kinase activity receptor signaling protein activity protein binding ATP binding integral to plasma membrane protein amino acid phosphorylation intracellular signaling cascade multicellular organismal development central nervous system development endosome transport transferase activity cell differentiation
235849_at	0.480	6.914	2.145	4.847e-02	0.319	-4.140	SCARA5	scavenger receptor class A, member 5 (putative)	8	-27783668	BE787752	286133	8p21.1	Hs.591833	6	receptor activity scavenger receptor activity iron ion binding protein binding plasma membrane integral to plasma membrane ion transport cellular iron ion homeostasis endocytosis cell surface cellular response to heat iron ion transmembrane transport protein homotrimerization ferritin receptor activity
212742_at	-0.408	9.480	-2.145	4.847e-02	0.319	-4.140	RNF115	ring finger protein 115	1	144322392	AL530462	27246	1q21.1	Hs.523550	8	protein binding zinc ion binding metal ion binding
35436_at	-0.190	7.607	-2.145	4.849e-02	0.319	-4.140	GOLGA2	golgi autoantigen, golgin subfamily a, 2	9	-130057928	L06147	2801	9q34.11	Hs.155827	45	protein binding Golgi apparatus membrane
219948_x_at	-0.162	2.013	-2.145	4.850e-02	0.319	-4.140	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3	4	-69828765	NM_024743	79799	4q13.2	Hs.122583	5	metabolic process glucuronosyltransferase activity membrane integral to membrane	Pentose and glucuronate interconversions Ascorbate and aldarate metabolism Androgen and estrogen metabolism Starch and sucrose metabolism Retinol metabolism Porphyrin and chlorophyll metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways
210600_s_at	0.206	2.526	2.145	4.850e-02	0.319	-4.140	GRK4	G protein-coupled receptor kinase 4	4	2935140	U33054	2868	4p16.3	Hs.32959	27	nucleotide binding G-protein coupled receptor kinase activity signal transducer activity ATP binding protein amino acid phosphorylation signal transduction regulation of G-protein coupled receptor protein signaling pathway transferase activity	Chemokine signaling pathway Endocytosis
205621_at	-0.208	6.865	-2.145	4.850e-02	0.319	-4.140	ALKBH1	alkB, alkylation repair homolog 1 (E. coli)	14	-77208501	NM_006020	8846	14q24.3	Hs.94542	6	DNA dealkylation
207923_x_at	0.220	5.439	2.145	4.851e-02	0.319	-4.141	PAX8	paired box 8	2	-113690044	NM_013953	7849	2q12-q14	Hs.469728	55	transcription factor activity thyroid-stimulating hormone receptor activity protein binding nucleus nucleoplasm multicellular organismal development anatomical structure morphogenesis transcription activator activity cell differentiation regulation of transcription positive regulation of transcription, DNA-dependent	Pathways in cancer Thyroid cancer
205357_s_at	0.272	6.117	2.145	4.852e-02	0.319	-4.141	AGTR1	angiotensin II receptor, type 1	3	149898347, 149930656	NM_000685	185	3q21-q25	Hs.477887 Hs.719071	524	regulation of cell growth angiotensin type I receptor activity angiotensin type I receptor activity kidney development renin-angiotensin regulation of aldosterone production regulation of blood vessel size by renin-angiotensin regulation of natriuresis receptor activity G-protein coupled receptor activity angiotensin type II receptor activity plasma membrane integral to plasma membrane oxygen and reactive oxygen species metabolic process signal transduction acetyltransferase activator activity positive regulation of foam cell differentiation positive regulation of cholesterol esterification regulation of vasoconstriction regulation of vasoconstriction regulation of vasoconstriction calcium-mediated signaling bradykinin receptor binding positive regulation of cellular protein metabolic process positive regulation of phospholipase A2 activity positive regulation of NAD(P)H oxidase activity low-density lipoprotein particle remodeling regulation of cell proliferation regulation of vasodilation protein heterodimerization activity positive regulation of inflammatory response elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)	Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction Renin-angiotensin system
226222_at	-0.256	5.512	-2.145	4.853e-02	0.319	-4.141	KIAA1432	KIAA1432	9	5619326, 5646582	AB037853	57589	9p24.1	Hs.211520	5	membrane integral to membrane
227529_s_at	0.260	3.035	2.145	4.853e-02	0.319	-4.141	AKAP12	A kinase (PRKA) anchor protein 12	6	151602826, 151688358	BF511276	9590	6q24-q25	Hs.371240	33	nucleus cytoplasm cytoskeleton plasma membrane cell cortex protein targeting signal transduction G-protein coupled receptor protein signaling pathway protein kinase A binding
201251_at	-0.515	8.477	-2.145	4.853e-02	0.319	-4.141	PKM2	pyruvate kinase, muscle	15	-70278423	NM_002654	5315	15q22	Hs.534770	55	nucleotide binding magnesium ion binding pyruvate kinase activity pyruvate kinase activity protein binding ATP binding nucleus cytoplasm cytosol cytosol glycolysis programmed cell death transferase activity potassium ion binding	Glycolysis / Gluconeogenesis Purine metabolism Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways Type II diabetes mellitus
209596_at	1.003	6.122	2.144	4.855e-02	0.319	-4.141	MXRA5	matrix-remodelling associated 5	X	-3236607	AF245505	25878	Xp22.33	Hs.369422	5	protein binding extracellular region
224895_at	0.398	8.841	2.144	4.857e-02	0.319	-4.142	YAP1	Yes-associated protein 1, 65kDa	11	101486419	AA557632	10413	11q13	Hs.503692	46	protein binding
218512_at	0.227	8.191	2.144	4.857e-02	0.319	-4.142	WDR12	WD repeat domain 12	2	-203453568	NM_018256	55759	2q33.2	Hs.73291	12	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding nucleus nucleoplasm nucleolus rRNA processing Notch signaling pathway cell proliferation preribosome, large subunit precursor ribosomal large subunit biogenesis PeBoW complex
225078_at	0.229	6.685	2.144	4.858e-02	0.319	-4.142	EMP2	epithelial membrane protein 2	16	-10529780	AV686514	2013	16p13.2	Hs.531561	17	cell proliferation membrane integral to membrane
214657_s_at	-0.356	5.063	-2.144	4.858e-02	0.319	-4.142	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)	11	64946844, 64946844	AU134977	283131	11q13.1	Hs.523789 Hs.648467	6
207540_s_at	0.265	3.888	2.144	4.861e-02	0.319	-4.142	SYK	spleen tyrosine kinase	9	92603832, 92604027, 92629525	NM_003177	6850	9q22	Hs.371720	213	nucleotide binding serotonin secretion non-membrane spanning protein tyrosine kinase activity receptor signaling protein tyrosine kinase activity integrin binding protein binding ATP binding cytoplasm plasma membrane protein complex assembly leukocyte adhesion enzyme linked receptor protein signaling pathway integrin-mediated signaling pathway intracellular signaling cascade activation of JUN kinase activity cell proliferation organ morphogenesis transferase activity leukotriene biosynthetic process B cell receptor complex neutrophil chemotaxis T cell receptor complex positive regulation of mast cell degranulation beta selection interspecies interaction between organisms positive regulation of interleukin-3 biosynthetic process positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process positive regulation of B cell differentiation positive regulation of gamma-delta T cell differentiation positive regulation of alpha-beta T cell differentiation positive regulation of alpha-beta T cell proliferation protein amino acid autophosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling B cell receptor signaling pathway	Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis
221504_s_at	-0.319	7.538	-2.144	4.863e-02	0.319	-4.143	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	8	-54790667, -54790667	AF112204	51606	8q11.2	Hs.491737	20	vacuolar proton-transporting V-type ATPase, V1 domain protein binding cytosol plasma membrane ion transport endocytosis vacuolar acidification ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity enzyme regulator activity interspecies interaction between organisms proton-transporting ATPase activity, rotational mechanism regulation of defense response to virus by virus	Oxidative phosphorylation Metabolic pathways Lysosome Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection
209686_at	0.387	3.632	2.143	4.864e-02	0.319	-4.143	S100B	S100 calcium binding protein B	21	-46842958	BC001766	6285	21q22.3	Hs.422181	131	ruffle calcium ion binding nucleus cytoplasm cytoplasm axonogenesis central nervous system development learning or memory zinc ion binding cell proliferation protein homodimerization activity protein homodimerization activity S100 beta binding tau protein binding calcium-dependent protein binding
224621_at	-0.211	8.366	-2.143	4.868e-02	0.319	-4.144	MAPK1	mitogen-activated protein kinase 1	22	-20453318, -20443946	AA129773	5594	22q11.2 22q11.21	Hs.431850	822	MAPKKK cascade nucleotide binding phosphotyrosine binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol cytoskeleton protein amino acid phosphorylation induction of apoptosis chemotaxis response to DNA damage stimulus cell cycle Ras protein signal transduction synaptic transmission organ morphogenesis transferase activity MAP kinase 2 activity cytosine metabolic process lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to exogenous dsRNA interspecies interaction between organisms negative regulation of cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway	MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation TGF-beta signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Type II diabetes mellitus Alzheimer's disease Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer
238416_x_at	0.256	4.202	2.143	4.869e-02	0.319	-4.144	ZC3H18	zinc finger CCCH-type containing 18	16	87164289	BF968618	124245	16q24.2	Hs.93670	8	nucleic acid binding nucleus zinc ion binding metal ion binding
230597_at	0.242	5.263	2.143	4.869e-02	0.319	-4.144	SLC7A3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	X	-70062154	AI963203	84889	Xq13.1	Hs.175220	11	plasma membrane transport amino acid transport amino acid transmembrane transporter activity arginine transmembrane transporter activity L-lysine transmembrane transporter activity cationic amino acid transmembrane transporter activity arginine transport lysine transport integral to membrane
1560274_at	-0.225	2.481	-2.143	4.870e-02	0.319	-4.144	WTAP	Wilms tumor 1 associated protein	6	160068141, 160068141, 160068609	BF679507	9589	6q25-q27	Hs.446091 Hs.710715	16	nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane
232845_at	0.257	5.948	2.143	4.870e-02	0.319	-4.144	CDH23	cadherin-like 23	10	72826709, 72826709	AL122081	64072	10q21-q22	Hs.656032	37	calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion sensory perception of sound integral to membrane calcium-dependent cell-cell adhesion stereocilium photoreceptor cell maintenance response to stimulus equilibrioception
216971_s_at	-0.264	5.295	-2.143	4.871e-02	0.319	-4.144	PLEC1	plectin 1, intermediate filament binding protein 500kDa	8	-145061308, -145061308, -145061308, -145061308, -145061308, -145061308, -145061308, -145061308	Z54367	5339	8q24	Hs.434248	58	actin binding cytoplasm cytoskeleton plasma membrane structural constituent of muscle
211024_s_at	0.205	3.334	2.143	4.872e-02	0.319	-4.144	NKX2-1	NK2 homeobox 1	14	-36055352, -36055352	BC006221	7080	14q13	Hs.94367	87	negative regulation of transcription from RNA polymerase II promoter neuron migration specific RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus nucleoplasm transcription factor complex pattern specification process axon guidance brain development endoderm development organ morphogenesis promoter binding transcription activator activity transcription activator activity cerebral cortex cell migration forebrain dorsal/ventral pattern formation forebrain neuron fate commitment cerebral cortex GABAergic interneuron differentiation lung development thyroid gland development positive regulation of transcription from RNA polymerase II promoter anatomical structure formation involved in morphogenesis
222490_at	-0.352	6.927	-2.142	4.872e-02	0.319	-4.144	POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	16	22216241	AK023160	55718	16p12.2	Hs.460298	9	DNA-directed RNA polymerase activity nucleus transcription
219763_at	-0.218	3.475	-2.142	4.873e-02	0.319	-4.144	DENND1A	DENN/MADD domain containing 1A	9	-125203690, -125181753	NM_024820	57706	9q33.3	Hs.568340	8	protein binding plasma membrane SH3 domain binding cell junction dendrite clathrin coated vesicle membrane cytoplasmic vesicle cell soma synapse synaptic vesicle endocytosis
213901_x_at	-0.351	7.998	-2.142	4.873e-02	0.319	-4.145	RBM9	RNA binding motif protein 9	22	-34464728, -34464728	AW149379	23543	22q13.1	Hs.282998	18	nucleotide binding transcription corepressor activity RNA binding nucleus cytoplasm mRNA processing transcription factor binding RNA splicing RNA metabolic process negative regulation of transcription estrogen receptor signaling pathway regulation of cell proliferation
227788_at	-0.331	8.148	-2.142	4.873e-02	0.319	-4.145	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	3	180853626	AW295324	8975	3q26.2-q26.3	Hs.175322	11	cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding
229970_at	-0.396	4.674	-2.142	4.874e-02	0.319	-4.145	KBTBD7	kelch repeat and BTB (POZ) domain containing 7	13	-40663710	BE672291	84078	13q14.11	Hs.63841	9	molecular_function protein binding cellular_component biological_process
235878_at	0.224	3.801	2.142	4.874e-02	0.319	-4.145	TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	2	9901021	AA780048	9014	2p25	Hs.584833	15	transcription factor activity nucleus nucleoplasm transcription, DNA-dependent regulation of transcription
1556960_a_at	0.215	4.074	2.142	4.874e-02	0.319	-4.145	hCG_2007354	hCG2007354	12		AK057223	647589	12q24.33	Hs.703008	2
232025_at	0.200	5.863	2.142	4.875e-02	0.319	-4.145	SYT7	synaptotagmin VII	11	-61039360	AF038535	9066	11q12-q13.1	Hs.502730 Hs.684589	10	plasma membrane repair transporter activity calcium ion binding lysosome transport synaptic vesicle membrane integral to membrane cell junction cytoplasmic vesicle synapse
224240_s_at	0.172	4.561	2.142	4.878e-02	0.319	-4.145	CCL28	chemokine (C-C motif) ligand 28	5	-43417356	AF266504	56477	5p12	Hs.656904	16	extracellular region extracellular space chemotaxis immune response elevation of cytosolic calcium ion concentration chemokine activity	Cytokine-cytokine receptor interaction Chemokine signaling pathway
205580_s_at	0.214	3.849	2.142	4.880e-02	0.319	-4.146	HRH1	histamine receptor H1	3	11153778, 11171213, 11242668, 11269384	D28481	3269	3p25	Hs.1570	57	receptor activity G-protein coupled receptor activity histamine receptor activity plasma membrane integral to plasma membrane inflammatory response signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger synaptic transmission positive regulation of nitric oxide biosynthetic process	Calcium signaling pathway Neuroactive ligand-receptor interaction
234796_at	-0.186	3.822	-2.142	4.880e-02	0.319	-4.146	CABP7	calcium binding protein 7	22	28446343	AC004882	164633	22q12.2	Hs.643608	5	calcium ion binding
226422_at	-0.253	8.090	-2.142	4.880e-02	0.319	-4.146	ERGIC2	ERGIC and golgi 2	12	-29384845	AI760464	51290	12p11.22	Hs.339453	11	nucleus cytoplasm endoplasmic reticulum Golgi apparatus membrane integral to membrane vesicle-mediated transport
202687_s_at	0.575	7.051	2.141	4.882e-02	0.319	-4.146	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	3	-173706157	U57059	8743	3q26	Hs.478275	343	cytokine activity tumor necrosis factor receptor binding extracellular region extracellular space soluble fraction integral to plasma membrane induction of apoptosis immune response signal transduction cell-cell signaling zinc ion binding activation of pro-apoptotic gene products membrane positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding	Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity
213778_x_at	-0.167	6.100	-2.141	4.882e-02	0.319	-4.146	ZNF276	zinc finger protein 276	16	88314893, 88315452	AI983201	92822	16q24.3	Hs.290154	8	DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding
225085_at	-0.263	6.216	-2.141	4.883e-02	0.319	-4.146	USP40	ubiquitin specific peptidase 40	2	-234048903	AA522888	55230	2q37.1	Hs.96513	10	ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity
221101_at	0.166	3.520	2.141	4.885e-02	0.320	-4.147	C14orf113	chromosome 14 open reading frame 113	14		NM_017630	54792	14q32.13	Hs.675410	1
215952_s_at	-0.165	11.767	-2.141	4.886e-02	0.320	-4.147	OAZ1	ornithine decarboxylase antizyme 1	19	2220519	AF090094	4946	19p13.3	Hs.446427	25	protein binding polyamine biosynthetic process ornithine decarboxylase inhibitor activity
212275_s_at	0.191	6.557	2.141	4.887e-02	0.320	-4.147	SRCAP	Snf2-related CREBBP activator protein	16	30617962	NM_006662	10847	16p11.2	Hs.647334	16	nucleotide binding DNA binding transcription coactivator activity helicase activity histone acetyltransferase activity ATP binding nucleus regulation of transcription from RNA polymerase II promoter chromatin modification hydrolase activity protein complex interspecies interaction between organisms regulation of transcription
228429_x_at	0.197	6.701	2.141	4.888e-02	0.320	-4.147	KIF9	kinesin family member 9	3	-47244520	BG168764	64147	3p21.31	Hs.373947	4	nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement
210127_at	0.226	4.139	2.141	4.890e-02	0.320	-4.148	RAB6B	RAB6B, member RAS oncogene family	3	-135025769	BC002510	51560	3q22.1	Hs.707804	10	nucleotide binding GTPase activity GTP binding Golgi apparatus retrograde vesicle-mediated transport, Golgi to ER small GTPase mediated signal transduction protein transport membrane vesicle-mediated transport
1554507_at	-0.174	1.951	-2.141	4.890e-02	0.320	-4.148	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2	11	89507465	BC027594	10003	11q14.3-q21	Hs.503560	6	carboxypeptidase activity proteolysis peptidase activity serine-type peptidase activity metallopeptidase activity dipeptidyl-peptidase activity zinc ion binding membrane integral to membrane dipeptidase activity metal ion binding
240027_at	-0.352	2.622	-2.140	4.892e-02	0.320	-4.148	LIN7A	lin-7 homolog A (C. elegans)	12	-79715301	BF062244	8825	12q21	Hs.144333	17	protein binding plasma membrane tight junction protein complex assembly exocytosis neurotransmitter secretion protein transport basolateral plasma membrane synaptosome cell junction synapse postsynaptic membrane synaptic vesicle transport
208668_x_at	0.248	10.511	2.140	4.894e-02	0.320	-4.148	HMGN2	high-mobility group nucleosomal binding domain 2	1	26671488	BC003689	3151	1p36.1	Hs.181163	23	chromatin DNA binding protein binding nucleus cytoplasm chromatin organization regulation of transcription, DNA-dependent
1554915_a_at	-0.362	3.308	-2.140	4.894e-02	0.320	-4.148	PDE12	phosphodiesterase 12	3	57517020	BC034978	201626	3p14.3	Hs.572993	3	hydrolase activity
210314_x_at	0.256	4.173	2.140	4.895e-02	0.320	-4.148	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13	17	7402332	AF114013	8741	17p13.1	Hs.54673	66	cytokine activity tumor necrosis factor receptor binding extracellular region extracellular space immune response signal transduction positive regulation of cell proliferation membrane positive regulation of isotype switching to IgA isotypes	Cytokine-cytokine receptor interaction
213435_at	-0.281	5.922	-2.139	4.901e-02	0.320	-4.149	SATB2	SATB homeobox 2	2	-199842468	AB028957	23314	2q33	Hs.516617	9	transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding
242201_at	0.408	5.241	2.139	4.902e-02	0.320	-4.150	PMS2L5	postmeiotic segregation increased 2-like 5	7	73944829, 73944829	AI418253	5383	7q11-q22	Hs.292996 Hs.647025	4	ATP binding mismatch repair mismatched DNA binding
215880_at	-0.181	4.811	-2.139	4.903e-02	0.320	-4.150	NAGLU	N-acetylglucosaminidase, alpha-	17	37941476	AI364950	4669	17q21	Hs.50727	21	alpha-N-acetylglucosaminidase activity lysosome nervous system development metabolic process hydrolase activity, acting on glycosyl bonds glycosaminoglycan metabolic process	Glycosaminoglycan degradation Metabolic pathways Lysosome
1570383_at	0.174	3.704	2.139	4.905e-02	0.320	-4.150	BMP1	bone morphogenetic protein 1	8	22078619, 22078619	AF289591	649	8p21.3	Hs.1274	38	cartilage condensation ossification metalloendopeptidase activity cytokine activity calcium ion binding extracellular space proteolysis multicellular organismal development growth factor activity peptidase activity zinc ion binding cell differentiation
244315_at	-0.171	2.021	-2.139	4.906e-02	0.320	-4.150	PLSCR1	phospholipid scramblase 1	3	-147715656	BE066040	5359	3q23	Hs.130759	34	calcium ion binding protein binding plasma membrane response to virus integral to membrane phospholipid scrambling SH3 domain binding phospholipid scramblase activity platelet activation
215867_x_at	-0.250	5.200	-2.139	4.907e-02	0.320	-4.151	CA12	carbonic anhydrase XII	15	-61402782	AL050025	771	15q22	Hs.210995	27	carbonate dehydratase activity cytoplasm plasma membrane one-carbon metabolic process zinc ion binding integral to membrane lyase activity metal ion binding	Nitrogen metabolism
217789_at	-0.250	6.482	-2.139	4.908e-02	0.320	-4.151	SNX6	sorting nexin 6	14	-34100368, -34100368	NM_021249	58533	14q13.1	Hs.583855	7	protein binding intracellular cytoplasm intracellular protein transport cell communication negative regulation of epidermal growth factor receptor activity negative regulation of transcription negative regulation of transforming growth factor beta receptor signaling pathway phosphoinositide binding protein homodimerization activity
231667_at	0.272	5.016	2.138	4.911e-02	0.320	-4.151	SLC39A5	solute carrier family 39 (metal ion transporter), member 5	12	54910086, 54910767	AW614558	283375	12q13.3	Hs.591018	7	plasma membrane ion transport zinc ion transport zinc ion binding integral to membrane basolateral plasma membrane metal ion transport metal ion transmembrane transporter activity
202260_s_at	0.226	5.791	2.138	4.912e-02	0.320	-4.151	STXBP1	syntaxin binding protein 1	9	129414306	NM_003165	6812	9q34.1	Hs.288229	38	protein binding cytoplasm mitochondrion vesicle docking during exocytosis axon target recognition protein transport membrane synaptic vesicle maturation vesicle-mediated transport negative regulation of synaptic transmission, GABAergic
47550_at	0.206	4.324	2.138	4.913e-02	0.320	-4.152	LZTS1	leucine zipper, putative tumor suppressor 1	8	-20147956	N21184	11178	8p22	Hs.521432	11	transcription factor activity protein binding nucleus cytoplasm Golgi apparatus plasma membrane transcription regulation of transcription, DNA-dependent cell cycle postsynaptic density cell junction cell projection dendritic spine synapse postsynaptic membrane
212556_at	-0.431	7.542	-2.138	4.914e-02	0.321	-4.152	SCRIB	scribbled homolog (Drosophila)	8	-144945077	AI469403	23513	8q24.3	Hs.436329	37	protein binding cytoplasm membrane
215300_s_at	0.186	2.597	2.138	4.915e-02	0.321	-4.152	FMO5	flavin containing monooxygenase 5	1	-145124461, -145122508	AK022172	2330	1q21.1	Hs.642706 Hs.719397	18	monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome biological_process membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction	Drug metabolism - cytochrome P450
221023_s_at	0.144	6.310	2.138	4.917e-02	0.321	-4.152	KCNH6	potassium voltage-gated channel, subfamily H (eag-related), member 6	17	58954426, 58954426	NM_030779	81033	17q23.3	Hs.591177	6	voltage-gated ion channel activity voltage-gated potassium channel activity regulation of transcription, DNA-dependent ion transport potassium ion transport signal transduction membrane integral to membrane potassium ion binding
235995_at	0.218	4.396	2.138	4.917e-02	0.321	-4.152	PUM2	pumilio homolog 2 (Drosophila)	2	-20311933	BF514625	23369	2p22-p21	Hs.467824	18	RNA binding protein binding cytoplasm regulation of translation
226188_at	-0.559	9.540	-2.138	4.918e-02	0.321	-4.153	HSPC159	galectin-related protein	2	64534830	AK025603	29094	2p14	Hs.372208	9	sugar binding intracellular
201198_s_at	-0.290	8.426	-2.138	4.918e-02	0.321	-4.153	PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	2	231629852	AI860431	5707	2q37.1	Hs.3887	43	proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	Proteasome
232523_at	-0.635	6.578	-2.137	4.919e-02	0.321	-4.153	MEGF10	multiple EGF-like-domains 10	5	126654354	AU144892	84466	5q33	Hs.438709	9	protein binding plasma membrane phagocytosis cell adhesion integral to membrane
209121_x_at	0.234	7.887	2.137	4.920e-02	0.321	-4.153	NR2F2	nuclear receptor subfamily 2, group F, member 2	15	94670160, 94675114, 94676797, 94677572	M64497	7026	15q26	Hs.657455	27	transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding
222489_s_at	-0.272	7.460	-2.137	4.922e-02	0.321	-4.153	WRNIP1	Werner helicase interacting protein 1	6	2710664	AA621580	56897	6p25.2	Hs.236828	14	nucleotide binding DNA synthesis during DNA repair DNA binding protein binding protein binding ATP binding nucleus response to DNA damage stimulus hydrolase activity ATPase activity regulation of DNA replication initiation
216388_s_at	0.255	5.046	2.137	4.922e-02	0.321	-4.153	LTB4R	leukotriene B4 receptor	14	23850544, 23852152	U33448	1241	14q11.2-q12	Hs.567248	43	nucleotide binding leukotriene B4 receptor activity receptor activity plasma membrane integral to plasma membrane cell motion muscle contraction inflammatory response immune response signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	Neuroactive ligand-receptor interaction
225748_at	-0.242	7.010	-2.137	4.923e-02	0.321	-4.153	LTV1	LTV1 homolog (S. cerevisiae)	6	144206200	AI458051	84946	6q24.2	Hs.185675	2
222876_s_at	0.186	5.383	2.137	4.924e-02	0.321	-4.154	ADAP2	ArfGAP with dual PH domains 2	17	26272879	AI761520	55803	17q11.2	Hs.514063	13	phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm mitochondrial envelope plasma membrane heart development ARF GTPase activator activity zinc ion binding protein binding, bridging regulation of ARF GTPase activity phosphatidylinositol-3,4-bisphosphate binding inositol 1,3,4,5 tetrakisphosphate binding metal ion binding
210804_x_at	-0.250	4.161	-2.137	4.924e-02	0.321	-4.154	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	2	-40192789, -40192789	AF128524	6546	2p23-p22	Hs.31961 Hs.468274 Hs.656261	39	calcium:sodium antiporter activity calcium ion binding calmodulin binding plasma membrane integral to plasma membrane ion transport sodium ion transport muscle contraction cell communication sodium ion transmembrane transporter activity calcium ion transmembrane transporter activity antiporter activity sodium ion binding cytosolic calcium ion transport	Calcium signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
235745_at	0.246	5.693	2.137	4.926e-02	0.321	-4.154	ERN1	endoplasmic reticulum to nucleus signaling 1	17	-59474121	AV704183	2081	17q24.2	Hs.133982 Hs.700027	27	nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding endoplasmic reticulum endoplasmic reticulum membrane mRNA processing protein modification process apoptosis induction of apoptosis response to unfolded protein activation of signaling protein activity involved in unfolded protein response cell cycle arrest membrane integral to membrane transferase activity hydrolase activity endoribonuclease activity, producing 5'-phosphomonoesters integral to endoplasmic reticulum membrane regulation of transcription protein amino acid autophosphorylation	Alzheimer's disease
224162_s_at	-0.412	7.935	-2.137	4.927e-02	0.321	-4.154	FBXO31	F-box protein 31	16	-85920444, -85920444	BC002985	79791	16q24.2	Hs.567582	10	cell cycle cyclin catabolic process SCF ubiquitin ligase complex modification-dependent protein catabolic process cyclin binding SCF-dependent proteasomal ubiquitin-dependent protein catabolic process G1 DNA damage checkpoint cellular response to DNA damage stimulus
234939_s_at	-0.261	3.097	-2.136	4.929e-02	0.321	-4.154	PHF12	PHD finger protein 12	17	-24263287, -24256396	AL161953	57649	17q11.2	Hs.714975	9	protein binding nucleus nucleolus zinc ion binding transcription repressor activity transcriptional repressor complex regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding
1552777_a_at	0.187	4.606	2.136	4.933e-02	0.321	-4.155	RAET1E	retinoic acid early transcript 1E	6	-150251293	NM_139165	135250	6q25.1	Hs.511818	11	protein binding plasma membrane immune response integral to membrane antigen processing and presentation MHC class I protein complex	Natural killer cell mediated cytotoxicity
212351_at	-0.218	7.433	-2.136	4.937e-02	0.321	-4.156	EIF2B5	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	3	185335503	U23028	8893	3q27.1	Hs.283551	39	ovarian follicle development translation initiation factor activity translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity nucleus cytoplasm eukaryotic translation initiation factor 2B complex response to heat response to heat response to heat response to glucose stimulus astrocyte development oligodendrocyte development transferase activity translation initiation factor binding negative regulation of translational initiation in response to stress myelination response to peptide hormone stimulus positive regulation of translational initiation cellular response to stimulus
224403_at	-0.287	3.725	-2.135	4.939e-02	0.321	-4.156	FCRL4	Fc receptor-like 4	1	-155810163	AF343661	83417	1q21	Hs.120260	15	receptor activity plasma membrane immune response integral to membrane
203278_s_at	-0.303	6.444	-2.135	4.939e-02	0.321	-4.156	PHF21A	PHD finger protein 21A	11	-45907445	NM_016621	51317	11p11.2	Hs.502458	11	histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding nucleus zinc ion binding chromatin modification regulation of transcription metal ion binding
233083_at	-0.182	4.034	-2.135	4.945e-02	0.322	-4.157	MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	4	75242692	AV706915	441024	4q13.3	Hs.479954	2	histidine biosynthetic process magnesium ion binding methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity binding purine nucleotide biosynthetic process one-carbon metabolic process cellular amino acid biosynthetic process methionine biosynthetic process folic acid and derivative biosynthetic process oxidoreductase activity hydrolase activity oxidation reduction
227038_at	-0.455	5.370	-2.134	4.948e-02	0.322	-4.158	SGMS2	sphingomyelin synthase 2	4	108965169, 109033868	AI963083	166929	4q25	Hs.595423	13	Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process sphingolipid metabolic process sphingomyelin biosynthetic process kinase activity transferase activity integral to Golgi membrane sphingomyelin synthase activity ceramide cholinephosphotransferase activity	Sphingolipid metabolism Metabolic pathways
233408_at	0.269	4.006	2.134	4.952e-02	0.322	-4.159	PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2	8	69027156, 69027156	AW236486	80243	8q13.2	Hs.591867	6	guanyl-nucleotide exchange factor activity protein binding intracellular G-protein coupled receptor protein signaling pathway intracellular signaling cascade Rac GTPase activator activity Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction
219110_at	0.193	6.871	2.134	4.952e-02	0.322	-4.159	GAR1	GAR1 ribonucleoprotein homolog (yeast)	4	110956114	NM_018983	54433	4q25	Hs.69851	15	cation channel activity nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing Cajal body rRNA binding
215482_s_at	-0.263	7.900	-2.134	4.952e-02	0.322	-4.159	EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	2	-27440722, -27440722	AJ011307	8890	2p23.3	Hs.169474	29	ovarian follicle development translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm eukaryotic translation initiation factor 2B complex translational initiation regulation of translation response to heat response to heat response to glucose stimulus oligodendrocyte development translation initiation factor binding negative regulation of translational initiation in response to stress myelination response to peptide hormone stimulus cellular metabolic process cellular response to stimulus
203399_x_at	0.192	3.589	2.134	4.952e-02	0.322	-4.159	PSG3	pregnancy specific beta-1-glycoprotein 3	19	-47917633	NM_021016	5671	19q13.2	Hs.654413	13	extracellular region defense response female pregnancy
212764_at	-0.236	9.713	-2.134	4.953e-02	0.322	-4.159	ZEB1	zinc finger E-box binding homeobox 1	10	31647429, 31647717, 31647752, 31648106, 31650069	AI806174	6935	10p11.2	Hs.124503	52	negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding
236314_at	0.253	5.271	2.134	4.953e-02	0.322	-4.159	EPM2AIP1	EPM2A (laforin) interacting protein 1	3	-37002361	AW162758	9852	3p22.1	Hs.28020	8	endoplasmic reticulum
37943_at	-0.298	6.013	-2.134	4.954e-02	0.322	-4.159	ZFYVE26	zinc finger, FYVE domain containing 26	14	-67282989	AB002319	23503	14q24.1	Hs.98041	6	cell death zinc ion binding metal ion binding
242176_at	-0.215	5.443	-2.134	4.954e-02	0.322	-4.159	MEF2A	myocyte enhancer factor 2A	15	97923655, 97990705	AA491228	4205	15q26	Hs.268675	77	transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding
226359_at	0.207	4.197	2.133	4.956e-02	0.322	-4.159	GTPBP1	GTP binding protein 1	22	37431752	BF514508	9567	22q13.1	Hs.276925	11	nucleotide binding GTPase activity GTP binding immune response signal transduction
224715_at	0.197	5.901	2.133	4.957e-02	0.322	-4.159	WDR34	WD repeat domain 34	9	-130435760	BG338983	89891	9q34.11	Hs.495240	3
222304_x_at	-0.630	7.880	-2.133	4.957e-02	0.322	-4.159	OR7E47P	olfactory receptor, family 7, subfamily E, member 47 pseudogene	12		AW514038	26628	12q13.13	Hs.524431	2
231975_s_at	-0.366	5.472	-2.133	4.957e-02	0.322	-4.159	MIER3	mesoderm induction early response 1, family member 3	5	-56251185	AK002183	166968	5q11.2	Hs.657594	7	DNA binding nucleus regulation of transcription
208401_s_at	0.223	4.699	2.133	4.958e-02	0.322	-4.160	GLP1R	glucagon-like peptide 1 receptor	6	39124534	U01157	2740	6p21	Hs.389103	31	glucagon receptor activity plasma membrane response to stress G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity elevation of cytosolic calcium ion concentration learning or memory regulation of heart contraction peptide receptor activity, G-protein coupled integral to membrane cAMP-mediated signaling insulin secretion hormone secretion	Neuroactive ligand-receptor interaction
223620_at	0.547	3.877	2.133	4.959e-02	0.322	-4.160	GPR34	G protein-coupled receptor 34	X	41433169	AF039686	2857	Xp11.4-p11.3	Hs.495989	10	receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway purinergic nucleotide receptor activity, G-protein coupled
227930_at	-0.334	7.574	-2.133	4.960e-02	0.322	-4.160	EIF2C4	eukaryotic translation initiation factor 2C, 4	1	36046414	AI669957	192670	1p34.3	Hs.471492	8	cytoplasmic mRNA processing body RNA binding protein binding cytoplasm mRNA catabolic process regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation
204516_at	-0.301	6.943	-2.133	4.960e-02	0.322	-4.160	ATXN7	ataxin 7	3	63825272	BG390306	6314	3p21.1-p12	Hs.476595	37	protein binding intracellular nucleus nucleolus cytoplasm nucleus organization visual perception cell death zinc ion binding nuclear matrix histone deubiquitination regulation of transcription
222042_x_at	0.151	5.617	2.133	4.965e-02	0.322	-4.161	MEX3D	mex-3 homolog D (C. elegans)	19	-1505667	BF056534	399664	19p13.3	Hs.436495	4	RNA binding protein binding nucleus cytoplasm zinc ion binding metal ion binding
207079_s_at	-0.366	7.534	-2.133	4.965e-02	0.322	-4.161	MED6	mediator complex subunit 6	14	-70120709	NM_005466	10001	14q24.2	Hs.497353	22	RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter
202310_s_at	0.897	5.535	2.133	4.966e-02	0.322	-4.161	COL1A1	collagen, type I, alpha 1	17	-45616455	K01228	1277	17q21.33	Hs.172928 Hs.681002	360	ossification blood vessel development extracellular matrix structural constituent extracellular region extracellular region collagen collagen type I plasma membrane response to nutrient visual perception sensory perception of sound response to mechanical stimulus response to inorganic substance collagen fibril organization response to corticosteroid stimulus collagen biosynthetic process tooth mineralization response to hydrogen peroxide identical protein binding response to peptide hormone stimulus skin morphogenesis platelet-derived growth factor binding embryonic skeletal system development response to cAMP	Focal adhesion ECM-receptor interaction
244131_at	0.168	5.149	2.132	4.967e-02	0.322	-4.161	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	7	-26196080	AA904506	3181	7p15	Hs.487774	54	nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm RNA splicing heterogeneous nuclear ribonucleoprotein complex single-stranded telomeric DNA binding RNA transport
215623_x_at	-0.228	3.684	-2.132	4.967e-02	0.322	-4.161	SMC4	structural maintenance of chromosomes 4	3	161600123, 161601040	AK002200	10051	3q26.1	Hs.58992	14	nucleotide binding condensin complex condensin complex protein binding ATP binding nucleus chromosome cytoplasm cell cycle mitotic chromosome condensation protein heterodimerization activity cell division
207213_s_at	-0.452	7.347	-2.132	4.968e-02	0.322	-4.161	USP2	ubiquitin specific peptidase 2	11	-118731134, -118731134	NM_004205	9099	11q23.3	Hs.524085	15	cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding cytoplasm plasma membrane ubiquitin-dependent protein catabolic process peptidase activity
206150_at	0.197	6.116	2.132	4.969e-02	0.322	-4.161	CD27	CD27 molecule	12	6424311	NM_001242	939	12p13	Hs.355307	53	transmembrane receptor activity protein binding protein binding extracellular region integral to plasma membrane apoptosis anti-apoptosis anti-apoptosis induction of apoptosis immune response cell surface receptor linked signal transduction release of cytoplasmic sequestered NF-kappaB membrane immunoglobulin mediated immune response caspase inhibitor activity positive regulation of B cell differentiation positive regulation of JNK cascade	Cytokine-cytokine receptor interaction
214181_x_at	0.322	4.941	2.132	4.970e-02	0.322	-4.162	LST1	leukocyte specific transcript 1	6	31661949, 31662603, 3000093, 3000747, 2801557, 2802211	AI735692	7940	6p21.3	Hs.436066	20	cell morphogenesis molecular_function protein binding cytoplasm Golgi apparatus immune response regulation of cell shape anatomical structure morphogenesis membrane integral to membrane dendrite development negative regulation of lymphocyte proliferation
1560147_at	0.191	2.911	2.132	4.970e-02	0.322	-4.162	LOC100131176	similar to hCG1991662	7		AK095986	100131176	7q36.1	Hs.659231
205281_s_at	-0.304	4.437	-2.132	4.974e-02	0.322	-4.162	PIGA	phosphatidylinositol glycan anchor biosynthesis, class A	X	-15247498	NM_002641	5277	Xp22.1	Hs.137154	27	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex protein binding endoplasmic reticulum endoplasmic reticulum membrane biosynthetic process positive regulation of metabolic process membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity, transferring glycosyl groups phosphatidylinositol N-acetylglucosaminyltransferase activity	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways
207124_s_at	0.181	4.594	2.132	4.974e-02	0.322	-4.162	GNB5	guanine nucleotide binding protein (G protein), beta 5	15	-50200414, -50200414	NM_006578	10681	15q21.2	Hs.155090	26	GTPase activity signal transducer activity protein binding nucleus heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway	Chemokine signaling pathway
229956_at	-0.238	3.017	-2.131	4.975e-02	0.322	-4.163	NR2C1	nuclear receptor subfamily 2, group C, member 1	12	-93948315, -93938188	AI659426	7181	12q22	Hs.108301 Hs.707524	17	negative regulation of transcription from RNA polymerase II promoter transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity protein homodimerization activity histone deacetylase binding sequence-specific DNA binding metal ion binding
201886_at	0.167	7.279	2.131	4.977e-02	0.322	-4.163	DCAF11	DDB1 and CUL4 associated factor 11	14	23653745, 23653825, 23654331, 23654333	NM_025230	80344	14q11.2	Hs.525251	9	protein binding
1553785_at	-0.191	4.126	-2.131	4.977e-02	0.322	-4.163	RASGEF1B	RasGEF domain family, member 1B	4	-82567242	NM_152545	153020	4q21.21	Hs.591696	4	guanyl-nucleotide exchange factor activity intracellular regulation of small GTPase mediated signal transduction
218022_at	-0.191	7.084	-2.131	4.977e-02	0.322	-4.163	VRK3	vaccinia related kinase 3	19	-55171535	NM_016440	51231	19q13	Hs.443330	7	nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity
200005_at	-0.291	8.377	-2.131	4.977e-02	0.322	-4.163	EIF3D	eukaryotic translation initiation factor 3, subunit D	22	-35236842	NM_003753	8664	22q13.1	Hs.55682	20	translation initiation factor activity translation initiation factor activity protein binding cytoplasm cytosol eukaryotic translation initiation factor 3 complex translational initiation translational initiation
242282_at	-0.152	6.080	-2.131	4.978e-02	0.322	-4.163	ZFPM1	zinc finger protein, multitype 1	16	87047514	AI889717	161882	16q24.2	Hs.632218	12	DNA binding protein binding intracellular nucleus heart development zinc ion binding regulation of transcription metal ion binding
205003_at	0.216	7.291	2.131	4.979e-02	0.322	-4.163	DOCK4	dedicator of cytokinesis 4	7	-111153399	NM_014705	9732	7q31.1	Hs.654652	16	guanyl-nucleotide exchange factor activity protein binding membrane SH3 domain binding PDZ domain binding Rac GTPase activator activity stereocilium Rac GTPase binding
214336_s_at	0.195	4.822	2.131	4.979e-02	0.322	-4.163	COPA	coatomer protein complex, subunit alpha	1	-158525000	AI621079	1314	1q23-q25	Hs.162121 Hs.685025	30	hormone activity structural molecule activity calcium ion binding extracellular region extracellular space soluble fraction cytoplasm endoplasmic reticulum microsome Golgi apparatus cytosol protein folding intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat pancreatic juice secretion cytoplasmic vesicle COPI coating of Golgi vesicle unfolded protein binding
224641_at	-0.348	9.844	-2.131	4.980e-02	0.322	-4.163	FYTTD1	forty-two-three domain containing 1	3	198960820, 198961020, 198961657	BF576005	84248	3q29	Hs.277533	6
203598_s_at	-0.385	7.006	-2.131	4.981e-02	0.322	-4.164	WBP4	WW domain binding protein 4 (formin binding protein 21)	13	40533696	AK000979	11193	13q14.11	Hs.411300	9	nucleic acid binding protein binding nucleus spliceosomal complex mRNA processing zinc ion binding RNA splicing nuclear speck metal ion binding
210342_s_at	0.230	4.705	2.131	4.982e-02	0.322	-4.164	TPO	thyroid peroxidase	2	1396239, 1397186	M17755	7173	2p25	Hs.467554	84	iodide peroxidase activity calcium ion binding integral to plasma membrane response to oxidative stress membrane oxidoreductase activity heme binding hormone biosynthetic process hydrogen peroxide catabolic process oxidation reduction	Tyrosine metabolism Metabolic pathways Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage Autoimmune thyroid disease
213157_s_at	0.233	5.644	2.131	4.983e-02	0.322	-4.164	WSCD1	WSC domain containing 1	17	5914657	BF115148	23302	17p13.2	Hs.370166	2	membrane integral to membrane
205968_at	-0.615	8.432	-2.131	4.983e-02	0.322	-4.164	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	2	17923425	NM_002252	3790	2p24	Hs.414489	12	voltage-gated ion channel activity delayed rectifier potassium channel activity protein binding cytoplasm Golgi apparatus plasma membrane ion transport potassium ion transport voltage-gated potassium channel complex potassium channel regulator activity integral to membrane potassium ion binding
209201_x_at	0.284	4.486	2.131	4.984e-02	0.322	-4.164	CXCR4	chemokine (C-X-C motif) receptor 4	2	-136588388, -136588388	L01639	7852	2q21	Hs.593413	604	activation of MAPK activity response to hypoxia actin binding G-protein coupled receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane apoptosis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor protein signaling pathway elevation of cytosolic calcium ion concentration response to virus coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity initiation of viral infection cell leading edge myosin light chain binding interspecies interaction between organisms	Cytokine-cytokine receptor interaction Chemokine signaling pathway Endocytosis Axon guidance Leukocyte transendothelial migration
218001_at	0.237	7.483	2.130	4.985e-02	0.322	-4.164	MRPS2	mitochondrial ribosomal protein S2	9	137532303	NM_016034	51116	9q34	Hs.382044	7	structural constituent of ribosome intracellular mitochondrion ribosome translation small ribosomal subunit
204625_s_at	0.207	4.774	2.130	4.986e-02	0.322	-4.164	ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	17	42686206	BF115658	3690	17q21.32	Hs.218040	581	receptor activity integrin binding plasma membrane cell-substrate junction assembly cell adhesion cell-matrix adhesion integrin-mediated signaling pathway blood coagulation integrin complex external side of plasma membrane negative regulation of foam cell differentiation negative regulation of lipid storage regulation of cell migration platelet alpha granule membrane negative regulation of lipid transport identical protein binding interspecies interaction between organisms negative regulation of low-density lipoprotein receptor biosynthetic process negative regulation of lipoprotein metabolic process	Focal adhesion ECM-receptor interaction Hematopoietic cell lineage Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC)
204967_at	-0.264	3.828	-2.130	4.986e-02	0.322	-4.164	SHROOM2	shroom family member 2	X	9714495	NM_001649	357	Xp22.3	Hs.567236	7	cell morphogenesis lens morphogenesis in camera-type eye cytoplasm cytoskeleton microtubule plasma membrane cell-cell adherens junction tight junction cell cortex multicellular organismal development brain development beta-catenin binding eye pigment granule organization amiloride-sensitive sodium channel activity apical plasma membrane cell migration protein domain specific binding negative regulation of actin filament depolymerization cortical actin cytoskeleton filamentous actin establishment of melanosome localization melanosome organization cell soma cellular pigment accumulation ear development apical protein localization cell-cell junction maintenance actin filament binding actin filament bundle formation
202172_at	-0.377	8.806	-2.130	4.987e-02	0.322	-4.165	VEZF1	vascular endothelial zinc finger 1	17	-53403908	BG035116	7716	17q22	Hs.463569	3	angiogenesis endothelial cell development DNA binding specific RNA polymerase II transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase II promoter cellular defense response zinc ion binding regulation of transcription metal ion binding
211319_at	0.188	3.565	2.130	4.987e-02	0.322	-4.165	RAE1	RAE1 RNA export 1 homolog (S. pombe)	20	55359551, 55360024	U85943	8480	20q13.31	Hs.371698	22	RNA binding nucleus nuclear outer membrane nuclear pore cytoplasm cytoskeleton mRNA export from nucleus microtubule binding
213571_s_at	-0.305	7.408	-2.130	4.988e-02	0.322	-4.165	EIF4E2	eukaryotic translation initiation factor 4E family member 2	2	233123600	BF516289	9470	2q37.1	Hs.292026 Hs.700929	15	RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation	mTOR signaling pathway Insulin signaling pathway
1552809_at	-0.245	3.148	-2.130	4.990e-02	0.322	-4.165	RFX4	regulatory factor X, 4 (influences HLA class II expression)	12	105501162, 105519079, 105602615	NM_002920	5992	12q24	Hs.388827	13	DNA binding nucleus regulation of transcription, DNA-dependent
203324_s_at	0.399	7.516	2.130	4.990e-02	0.322	-4.165	CAV2	caveolin 2	7	115926679	NM_001233	858	7q31.1	Hs.212332 Hs.603096	50	negative regulation of endothelial cell proliferation protein binding intracellular Golgi apparatus plasma membrane integral to plasma membrane caveola vesicle fusion mitochondrion organization endoplasmic reticulum organization transport vesicle protein homodimerization activity vesicle docking perinuclear region of cytoplasm skeletal muscle fiber development protein oligomerization	Focal adhesion
201729_s_at	-0.190	7.560	-2.130	4.992e-02	0.322	-4.165	KIAA0100	KIAA0100	17	-23965584	NM_014680	9703	17q11.2	Hs.151761	5	extracellular region tricarboxylic acid cycle malate dehydrogenase (acceptor) activity
220443_s_at	0.234	4.966	2.130	4.993e-02	0.322	-4.166	VAX2	ventral anterior homeobox 2	2	70981227	NM_012476	25806	2p13	Hs.249170	5	negative regulation of transcription from RNA polymerase II promoter transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent multicellular organismal development ectoderm development axonogenesis visual perception dorsal/ventral axis specification chromatin DNA binding sequence-specific DNA binding embryonic eye morphogenesis retina development in camera-type eye
218949_s_at	-0.560	7.515	-2.129	4.995e-02	0.322	-4.166	QRSL1	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1	6	107184133	NM_018292	55278	6q21	Hs.406917	7	nucleotide binding ATP binding translation ligase activity carbon-nitrogen ligase activity, with glutamine as amido-N-donor
223260_s_at	-0.348	5.083	-2.129	4.995e-02	0.322	-4.166	POLK	polymerase (DNA directed) kappa	5	74843412	AB027564	51426	5q13	Hs.715657	39	magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity nucleus DNA replication DNA repair response to DNA damage stimulus zinc ion binding transferase activity nucleotidyltransferase activity
216969_s_at	0.189	5.691	2.129	4.996e-02	0.322	-4.166	KIF22	kinesin family member 22	16	89374	AC002301	3835	16p11.2	Hs.613351	25	nucleotide binding kinetochore DNA binding microtubule motor activity protein binding ATP binding nucleus microtubule DNA repair microtubule-based movement mitosis
217839_at	-0.295	8.919	-2.129	4.997e-02	0.322	-4.166	TFG	TRK-fused gene	3	101910849	NM_006070	10342	3q12.2	Hs.518123	25	signal transducer activity cytoplasm identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade	Pathways in cancer Thyroid cancer
212292_at	0.199	5.988	2.129	4.997e-02	0.322	-4.167	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	13	-28981551	AW452623	6541	13q12-q14	Hs.14846	23	receptor activity integral to plasma membrane transport amino acid transport amino acid transmembrane transporter activity arginine transmembrane transporter activity arginine transport membrane
213349_at	-0.284	7.070	-2.129	4.998e-02	0.322	-4.167	TMCC1	transmembrane and coiled-coil domain family 1	3	-130849324, -130849324	AI934469	23023	3q22.1	Hs.477547 Hs.709936	6	membrane integral to membrane
238857_at	0.261	4.257	2.129	4.999e-02	0.322	-4.167	ATE1	arginyltransferase 1	10	-123492614	BE675478	11101	10q26.13	Hs.632080	6	arginyltransferase activity nucleus cytoplasm acyltransferase activity protein arginylation transferase activity modification-dependent protein catabolic process
213485_s_at	-0.283	6.322	-2.129	4.999e-02	0.322	-4.167	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	6	43507466	AK000002	89845	6p21.1	Hs.55879	12	nucleotide binding ATP binding plasma membrane transport integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances	ABC transporters

6921 Genes