Probe |
log2FC |
AveExpr |
t |
P.Value |
adj.P.Val |
B |
Symbol |
Description |
Chromosome |
Chromosome Location |
GenBank |
Gene |
Cytoband |
UniGene |
PubMed |
Gene Ontology |
Pathway |
1556113_at |
0.751 |
5.615 |
7.028 |
3.782e-06 |
0.039 |
3.863 |
DKFZp451A211 |
DKFZp451A211 protein |
13 |
|
BC036906 |
400169 |
13q34 |
Hs.646609 |
1 |
|
|
209190_s_at |
0.516 |
7.858 |
4.753 |
2.472e-04 |
0.172 |
0.569 |
DIAPH1 |
diaphanous homolog 1 (Drosophila) |
5 |
-140874771 |
AF051782 |
1729 |
5q31 |
Hs.529451 |
33 |
actin binding receptor binding cytoplasm cytoskeleton plasma membrane sensory perception of sound cellular component organization Rho GTPase binding actin cytoskeleton organization ruffle membrane cell projection |
Focal adhesion Regulation of actin cytoskeleton |
237116_at |
1.300 |
7.747 |
5.183 |
1.065e-04 |
0.162 |
1.260 |
LOC646903 |
hypothetical LOC646903 |
3 |
|
AI262277 |
646903 |
3q25.1 |
Hs.632559 |
1 |
|
|
231968_at |
0.737 |
7.931 |
5.594 |
4.862e-05 |
0.162 |
1.893 |
UGGT1 |
UDP-glucose glycoprotein glucosyltransferase 1 |
2 |
128565223, 128565251 |
AK025416 |
56886 |
2q14.3 |
Hs.598715 Hs.719174 |
10 |
UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding |
|
225337_at |
0.816 |
6.878 |
7.329 |
2.291e-06 |
0.039 |
4.231 |
ABHD2 |
abhydrolase domain containing 2 |
15 |
87432384 |
AI346910 |
11057 |
15q26.1 |
Hs.122337 Hs.705984 |
10 |
molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration |
|
227340_s_at |
-1.394 |
5.307 |
-4.679 |
2.862e-04 |
0.175 |
0.447 |
RGMB |
RGM domain family, member B |
5 |
98132898 |
AL117590 |
285704 |
5q15 |
Hs.526902 |
5 |
ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane |
|
219464_at |
-1.804 |
7.403 |
-6.790 |
5.661e-06 |
0.039 |
3.562 |
CA14 |
carbonic anhydrase XIV |
1 |
148496841 |
NM_012113 |
23632 |
1q21 |
Hs.528988 |
11 |
carbonate dehydratase activity zinc ion binding membrane integral to membrane lyase activity metal ion binding |
Nitrogen metabolism |
225185_at |
0.792 |
7.857 |
4.698 |
2.758e-04 |
0.175 |
0.478 |
MRAS |
muscle RAS oncogene homolog |
3 |
139549314, 139550197 |
BF343625 |
22808 |
3q22.3 |
Hs.527021 |
18 |
nucleotide binding GTPase activity GTP binding intracellular plasma membrane Ras protein signal transduction multicellular organismal development muscle organ development actin cytoskeleton organization GTP-dependent protein binding |
MAPK signaling pathway Tight junction Regulation of actin cytoskeleton |
1556051_a_at |
1.050 |
4.579 |
5.677 |
4.160e-05 |
0.152 |
2.017 |
BICD1 |
bicaudal D homolog 1 (Drosophila) |
12 |
32151451 |
CA777994 |
636 |
12p11.2-p11.1 |
Hs.505202 |
17 |
structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis |
|
201975_at |
0.335 |
9.896 |
2.922 |
1.039e-02 |
0.418 |
-2.589 |
CLIP1 |
CAP-GLY domain containing linker protein 1 |
12 |
-121321933 |
NM_002956 |
6249 |
12q24.3 |
Hs.524809 |
37 |
kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding |
|
206209_s_at |
-0.415 |
6.436 |
-3.245 |
5.359e-03 |
0.351 |
-2.026 |
CA4 |
carbonic anhydrase IV |
17 |
55582083 |
NM_000717 |
762 |
17q23 |
Hs.89485 |
30 |
carbonate dehydratase activity membrane fraction plasma membrane one-carbon metabolic process visual perception zinc ion binding lyase activity anchored to membrane metal ion binding response to stimulus |
Nitrogen metabolism |
217820_s_at |
0.771 |
8.103 |
3.627 |
2.433e-03 |
0.284 |
-1.354 |
ENAH |
enabled homolog (Drosophila) |
1 |
-223741156 |
NM_018212 |
55740 |
1q42.12 |
Hs.497893 |
37 |
actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding |
Regulation of actin cytoskeleton |
203913_s_at |
0.897 |
2.683 |
6.453 |
1.017e-05 |
0.062 |
3.118 |
HPGD |
hydroxyprostaglandin dehydrogenase 15-(NAD) |
4 |
-175647902, -175647902 |
AL574184 |
3248 |
4q34-q35 |
Hs.596913 |
47 |
prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction |
|
214788_x_at |
1.211 |
7.439 |
3.165 |
6.312e-03 |
0.363 |
-2.165 |
DDN |
dendrin |
12 |
-47675199 |
AA731713 |
23109 |
12q13.12 |
Hs.591044 |
5 |
nucleus cytoplasm endoplasmic reticulum plasma membrane dendrite cell projection perikaryon |
|
63825_at |
0.744 |
6.770 |
3.812 |
1.661e-03 |
0.263 |
-1.030 |
ABHD2 |
abhydrolase domain containing 2 |
15 |
87432384 |
AI557319 |
11057 |
15q26.1 |
Hs.122337 Hs.705984 |
10 |
molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration |
|
202763_at |
0.848 |
5.490 |
5.134 |
1.170e-04 |
0.162 |
1.183 |
CASP3 |
caspase 3, apoptosis-related cysteine peptidase |
4 |
-185785843 |
NM_004346 |
836 |
4q34 |
Hs.141125 |
552 |
B cell homeostasis release of cytochrome c from mitochondria cysteine-type endopeptidase activity cyclin-dependent protein kinase inhibitor activity protein binding nucleus nucleoplasm nucleolus cytoplasm mitochondrion cytosol cytosol plasma membrane DNA fragmentation involved in apoptosis proteolysis response to DNA damage stimulus heart development sensory perception of sound peptidase activity induction of apoptosis via death domain receptors induction of apoptosis by oxidative stress response to UV response to wounding keratinocyte differentiation nuclear fragmentation during apoptosis negative regulation of B cell proliferation response to tumor necrosis factor T cell homeostasis negative regulation of apoptosis cell fate commitment negative regulation of cyclin-dependent protein kinase activity negative regulation of activated T cell proliferation neuron apoptosis |
MAPK signaling pathway p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Parkinson's disease Amyotrophic lateral sclerosis (ALS) Huntington's disease Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer |
209005_at |
0.477 |
7.759 |
4.252 |
6.760e-04 |
0.211 |
-0.271 |
FBXL5 |
F-box and leucine-rich repeat protein 5 |
4 |
-15215251 |
AF157323 |
26234 |
4p15.32 |
Hs.643433 |
13 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding protein ubiquitination modification-dependent protein catabolic process |
|
203367_at |
0.371 |
6.604 |
3.562 |
2.785e-03 |
0.292 |
-1.469 |
DUSP14 |
dual specificity phosphatase 14 |
17 |
32924063 |
NM_007026 |
11072 |
17q12 |
Hs.91448 |
5 |
protein tyrosine phosphatase activity protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity |
MAPK signaling pathway |
221752_at |
0.632 |
6.388 |
4.042 |
1.038e-03 |
0.225 |
-0.632 |
SSH1 |
slingshot homolog 1 (Drosophila) |
12 |
-107709824, -107709824, -107700595 |
AL041728 |
54434 |
12q24.11 |
Hs.199763 |
23 |
cell morphogenesis actin binding protein tyrosine phosphatase activity protein binding cytoplasm cytoskeleton plasma membrane protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity lamellipodium actin cytoskeleton organization |
Regulation of actin cytoskeleton |
222572_at |
-1.430 |
9.672 |
-5.221 |
9.900e-05 |
0.162 |
1.319 |
PDP1 |
pyruvate dehyrogenase phosphatase catalytic subunit 1 |
8 |
94998258, 94998337, 94998350, 94998454, 94999167 |
BG542521 |
54704 |
8q22.1 |
Hs.22265 |
19 |
magnesium ion binding protein serine/threonine phosphatase activity [pyruvate dehydrogenase (lipoamide)] phosphatase activity calcium ion binding mitochondrion mitochondrial matrix protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity |
|
224983_at |
0.546 |
9.933 |
4.773 |
2.376e-04 |
0.172 |
0.602 |
SCARB2 |
scavenger receptor class B, member 2 |
4 |
-77298917 |
BF339821 |
950 |
4q21.1 |
Hs.349656 Hs.714206 |
24 |
receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane |
Lysosome |
202694_at |
0.612 |
4.352 |
4.914 |
1.798e-04 |
0.171 |
0.831 |
STK17A |
serine/threonine kinase 17a |
7 |
43589216 |
AW183478 |
9263 |
7p12-p14 |
Hs.709489 |
6 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity |
|
238575_at |
0.766 |
7.166 |
4.549 |
3.713e-04 |
0.186 |
0.231 |
OSBPL6 |
oxysterol binding protein-like 6 |
2 |
178767619, 178893216 |
AI094626 |
114880 |
2q31-q32.1 |
Hs.318775 |
7 |
lipid transport steroid metabolic process |
|
218868_at |
0.274 |
5.920 |
2.459 |
2.636e-02 |
0.521 |
-3.374 |
ACTR3B |
ARP3 actin-related protein 3 homolog B (yeast) |
7 |
152087783 |
NM_020445 |
57180 |
7q36.1 |
Hs.647117 |
8 |
nucleotide binding actin binding protein binding ATP binding cytoplasm cytoskeleton regulation of actin filament polymerization cell projection |
|
209212_s_at |
1.432 |
6.219 |
5.522 |
5.569e-05 |
0.162 |
1.784 |
KLF5 |
Kruppel-like factor 5 (intestinal) |
13 |
72531142 |
AB030824 |
688 |
13q22.1 |
Hs.508234 |
50 |
angiogenesis transcription factor activity RNA polymerase II transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter zinc ion binding positive regulation of cell proliferation microvillus assembly positive regulation of transcription metal ion binding |
|
203580_s_at |
0.556 |
8.015 |
3.824 |
1.622e-03 |
0.260 |
-1.009 |
SLC7A6 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 |
16 |
66855923 |
NM_003983 |
9057 |
16q22.1 |
Hs.653193 Hs.709557 |
6 |
plasma membrane integral to plasma membrane protein complex assembly cellular amino acid metabolic process transport amino acid transport amino acid transmembrane transporter activity antiporter activity |
|
222569_at |
0.833 |
6.279 |
3.949 |
1.256e-03 |
0.238 |
-0.793 |
UGGT1 |
UDP-glucose glycoprotein glucosyltransferase 1 |
2 |
128565223, 128565251 |
AU153746 |
56886 |
2q14.3 |
Hs.598715 Hs.719174 |
10 |
UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding |
|
222258_s_at |
1.508 |
5.744 |
6.234 |
1.503e-05 |
0.075 |
2.817 |
SH3BP4 |
SH3-domain binding protein 4 |
2 |
235525366 |
AF015043 |
23677 |
2q37.1-q37.2 |
Hs.516777 |
12 |
molecular_function signal transducer activity protein binding cellular_component nucleus coated pit endocytosis cell cycle biological_process membrane clathrin-coated vesicle cytoplasmic vesicle |
|
203700_s_at |
0.766 |
4.945 |
4.543 |
3.754e-04 |
0.187 |
0.222 |
DIO2 |
deiodinase, iodothyronine, type II |
14 |
-79733621, -79733621 |
NM_013989 |
1734 |
14q24.2-q24.3 |
Hs.202354 |
61 |
selenocysteine incorporation thyroxine 5'-deiodinase activity thyroid hormone generation selenium binding membrane integral to membrane thyroid hormone catabolic process hormone biosynthetic process oxidation reduction |
|
214999_s_at |
1.087 |
4.533 |
5.789 |
3.381e-05 |
0.132 |
2.182 |
RAB11FIP3 |
RAB11 family interacting protein 3 (class II) |
16 |
415668, 464850 |
AW243089 |
9727 |
16p13.3 |
Hs.531642 |
18 |
calcium ion binding protein binding protein transport membrane Rab GTPase binding recycling endosome |
Endocytosis |
211984_at |
0.844 |
10.402 |
5.446 |
6.427e-05 |
0.162 |
1.669 |
CALM1 |
calmodulin 1 (phosphorylase kinase, delta) |
14 |
89933125 |
AI653730 |
801 |
14q24-q31 |
Hs.282410 Hs.708270 |
181 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
204992_s_at |
0.823 |
10.321 |
4.141 |
8.473e-04 |
0.216 |
-0.461 |
PFN2 |
profilin 2 |
3 |
-151165380 |
NM_002628 |
5217 |
3q25.1-q25.2 |
Hs.91747 |
24 |
actin binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm regulation of actin polymerization or depolymerization actin cytoskeleton actin cytoskeleton organization |
Regulation of actin cytoskeleton |
213745_at |
0.835 |
2.958 |
3.346 |
4.348e-03 |
0.328 |
-1.848 |
ATRNL1 |
attractin-like 1 |
10 |
116843113 |
AW151108 |
26033 |
10q26 |
Hs.501127 |
3 |
binding sugar binding membrane integral to membrane |
|
203933_at |
0.525 |
6.466 |
4.562 |
3.614e-04 |
0.183 |
0.253 |
RAB11FIP3 |
RAB11 family interacting protein 3 (class II) |
16 |
415668, 464850 |
NM_014700 |
9727 |
16p13.3 |
Hs.531642 |
18 |
calcium ion binding protein binding protein transport membrane Rab GTPase binding recycling endosome |
Endocytosis |
201392_s_at |
0.706 |
8.226 |
3.834 |
1.591e-03 |
0.258 |
-0.993 |
IGF2R |
insulin-like growth factor 2 receptor |
6 |
160310120 |
BG031974 |
3482 |
6q26 |
Hs.487062 |
101 |
glycoprotein binding receptor activity insulin-like growth factor receptor activity transporter activity insulin-like growth factor binding mannose binding membrane fraction nucleus nuclear envelope lumen cytoplasm lysosome endosome Golgi apparatus integral to plasma membrane transport receptor-mediated endocytosis signal transduction membrane trans-Golgi network transport vesicle |
Lysosome |
211985_s_at |
0.794 |
10.126 |
4.601 |
3.347e-04 |
0.179 |
0.317 |
CALM1 |
calmodulin 1 (phosphorylase kinase, delta) |
14 |
89933125 |
AI653730 |
801 |
14q24-q31 |
Hs.282410 Hs.708270 |
181 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
219631_at |
0.463 |
5.780 |
2.780 |
1.388e-02 |
0.442 |
-2.834 |
LRP12 |
low density lipoprotein-related protein 12 |
8 |
-105570642 |
NM_024937 |
29967 |
8q22.2-q23.1 |
Hs.600630 |
8 |
receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth |
|
225028_at |
0.704 |
3.030 |
4.449 |
4.540e-04 |
0.193 |
0.063 |
LOC550643 |
hypothetical LOC550643 |
X |
56772442 |
AI417268 |
550643 |
Xp11.1 |
Hs.355559 |
1 |
|
|
231935_at |
0.831 |
7.696 |
3.346 |
4.353e-03 |
0.328 |
-1.849 |
ARPP-21 |
cyclic AMP-regulated phosphoprotein, 21 kD |
3 |
35658852, 35696119, 35697432 |
AL133109 |
10777 |
3p22.3 |
Hs.475902 Hs.713605 |
7 |
molecular_function nucleic acid binding cellular_component cytoplasm biological_process |
|
222730_s_at |
0.530 |
6.219 |
3.108 |
7.103e-03 |
0.372 |
-2.266 |
ZDHHC2 |
zinc finger, DHHC-type containing 2 |
8 |
17058206 |
AI814257 |
51201 |
8p21.3-p22 |
Hs.443852 |
8 |
zinc ion binding membrane integral to membrane palmitoyltransferase activity transferase activity protein palmitoylation metal ion binding |
|
228310_at |
0.869 |
5.551 |
4.670 |
2.914e-04 |
0.175 |
0.432 |
ENAH |
enabled homolog (Drosophila) |
1 |
-223741156 |
BF223300 |
55740 |
1q42.12 |
Hs.497893 |
37 |
actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding |
Regulation of actin cytoskeleton |
225323_at |
0.223 |
5.917 |
2.520 |
2.339e-02 |
0.507 |
-3.274 |
CC2D1B |
coiled-coil and C2 domain containing 1B |
1 |
-52588854 |
AW514783 |
200014 |
1p32.3 |
Hs.591451 |
6 |
|
|
225720_at |
1.264 |
8.371 |
4.270 |
6.513e-04 |
0.211 |
-0.239 |
SYNPO2 |
synaptopodin 2 |
4 |
120029443, 120029443 |
AW009747 |
171024 |
4q26 |
Hs.655519 |
14 |
actin binding protein binding nucleus cytoplasm |
|
224759_s_at |
0.347 |
6.947 |
2.817 |
1.286e-02 |
0.432 |
-2.769 |
C12orf23 |
chromosome 12 open reading frame 23 |
12 |
105873673 |
AK001731 |
90488 |
12q23.3 |
Hs.257664 |
3 |
membrane integral to membrane |
|
209345_s_at |
0.513 |
5.779 |
4.941 |
1.707e-04 |
0.171 |
0.874 |
PI4K2A |
phosphatidylinositol 4-kinase type 2 alpha |
10 |
99390432 |
AL561930 |
55361 |
10q24 |
Hs.25300 |
18 |
nucleotide binding magnesium ion binding 1-phosphatidylinositol 4-kinase activity protein binding ATP binding cytoplasm integral to plasma membrane phosphatidylinositol biosynthetic process membrane kinase activity transferase activity membrane raft |
|
204225_at |
0.773 |
7.940 |
3.331 |
4.490e-03 |
0.332 |
-1.875 |
HDAC4 |
histone deacetylase 4 |
2 |
-239634800 |
NM_006037 |
9759 |
2q37.3 |
Hs.20516 Hs.688314 |
83 |
histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter skeletal system development DNA binding histone deacetylase activity nucleus cytoplasm inflammatory response cell cycle multicellular organismal development nervous system development transcription factor binding negative regulation of cell proliferation transcription repressor activity chromatin modification hydrolase activity B cell differentiation positive regulation of protein sumoylation negative regulation of striated muscle development |
|
224722_at |
0.306 |
5.014 |
2.330 |
3.399e-02 |
0.553 |
-3.585 |
MIB1 |
mindbomb homolog 1 (Drosophila) |
18 |
17575542 |
BE048628 |
57534 |
18q11.2 |
Hs.140903 Hs.658808 |
15 |
blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding |
|
209288_s_at |
0.942 |
7.632 |
3.434 |
3.623e-03 |
0.314 |
-1.693 |
CDC42EP3 |
CDC42 effector protein (Rho GTPase binding) 3 |
2 |
-37724246 |
AL136842 |
10602 |
2p21 |
Hs.369574 |
17 |
protein binding cytoskeletal regulatory protein binding cytoplasm signal transduction regulation of cell shape actin cytoskeleton membrane |
|
222990_at |
0.338 |
9.423 |
3.378 |
4.075e-03 |
0.323 |
-1.792 |
UBQLN1 |
ubiquilin 1 |
9 |
-85464697 |
AW204104 |
29979 |
9q21.2-q21.3 9q22 |
Hs.9589 |
46 |
nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm |
|
202693_s_at |
0.637 |
5.990 |
3.156 |
6.434e-03 |
0.364 |
-2.181 |
STK17A |
serine/threonine kinase 17a |
7 |
43589216 |
AW194730 |
9263 |
7p12-p14 |
Hs.709489 |
6 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity |
|
211928_at |
0.404 |
8.973 |
3.400 |
3.894e-03 |
0.319 |
-1.754 |
DYNC1H1 |
dynein, cytoplasmic 1, heavy chain 1 |
14 |
101500617 |
AB002323 |
1778 |
14q32 14q32.3-qter |
Hs.649497 |
33 |
nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm Golgi apparatus cytoplasmic dynein complex microtubule microtubule-based movement mitotic spindle organization ATPase activity, coupled |
|
222433_at |
0.940 |
8.250 |
3.718 |
2.019e-03 |
0.273 |
-1.195 |
ENAH |
enabled homolog (Drosophila) |
1 |
-223741156 |
AK025108 |
55740 |
1q42.12 |
Hs.497893 |
37 |
actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding |
Regulation of actin cytoskeleton |
222434_at |
0.732 |
5.829 |
3.314 |
4.644e-03 |
0.335 |
-1.904 |
ENAH |
enabled homolog (Drosophila) |
1 |
-223741156 |
AI963713 |
55740 |
1q42.12 |
Hs.497893 |
37 |
actin binding cytoplasm cytoskeleton focal adhesion SH3 domain binding lamellipodium cell junction filopodium synapse intracellular transport WW domain binding |
Regulation of actin cytoskeleton |
225721_at |
1.186 |
8.704 |
4.711 |
2.687e-04 |
0.175 |
0.500 |
SYNPO2 |
synaptopodin 2 |
4 |
120029443, 120029443 |
AI658662 |
171024 |
4q26 |
Hs.655519 |
14 |
actin binding protein binding nucleus cytoplasm |
|
1563842_at |
-0.265 |
4.922 |
-3.389 |
3.980e-03 |
0.323 |
-1.772 |
PIGG |
phosphatidylinositol glycan anchor biosynthesis, class G |
4 |
482988 |
AK097244 |
54872 |
4p16.3 |
Hs.7099 |
8 |
protein binding endoplasmic reticulum endoplasmic reticulum membrane metabolic process membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity phosphotransferase activity, for other substituted phosphate groups CP2 mannose-ethanolamine phosphotransferase activity |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
214461_at |
2.945 |
4.182 |
5.265 |
9.097e-05 |
0.162 |
1.388 |
LBP |
lipopolysaccharide binding protein |
20 |
36408298 |
NM_004139 |
3929 |
20q11.23-q12 |
Hs.154078 |
58 |
lipopolysaccharide binding macrophage activation during immune response receptor binding extracellular region extracellular region extracellular space extracellular space nucleus lipid transport acute-phase response acute-phase response cellular defense response opsonization opsonization lipid binding lipopolysaccharide transport lipopolysaccharide-mediated signaling pathway detection of molecule of bacterial origin response to lipopolysaccharide negative regulation of tumor necrosis factor production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 4 signaling pathway positive regulation of macrophage activation cell surface binding innate immune response innate immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium Gram-negative bacterial cell surface binding Gram-negative bacterial cell surface binding Gram-positive bacterial cell surface binding positive regulation of respiratory burst during acute inflammatory response |
Toll-like receptor signaling pathway |
1554292_a_at |
0.459 |
3.121 |
4.956 |
1.654e-04 |
0.171 |
0.900 |
UHRF1BP1L |
UHRF1 binding protein 1-like |
12 |
-98987816, -98954993 |
BC014891 |
23074 |
12q23.1 |
Hs.620701 |
2 |
|
|
228647_at |
0.547 |
6.202 |
3.113 |
7.028e-03 |
0.372 |
-2.256 |
LOC100049716 |
hypothetical protein LOC100049716 |
12 |
|
AI675844 |
100049716 |
12p13.33 |
Hs.655804 |
1 |
|
|
205521_at |
0.862 |
5.928 |
4.733 |
2.569e-04 |
0.175 |
0.537 |
EXOG |
endo/exonuclease (5'-3'), endonuclease G-like |
3 |
38512766 |
BF511976 |
9941 |
3p21.3 |
Hs.517897 |
6 |
nucleic acid binding endonuclease activity cellular_component mitochondrion mitochondrial inner membrane biological_process membrane hydrolase activity metal ion binding |
Apoptosis |
205105_at |
0.723 |
6.980 |
3.940 |
1.278e-03 |
0.239 |
-0.807 |
MAN2A1 |
mannosidase, alpha, class 2A, member 1 |
5 |
109053054 |
NM_002372 |
4124 |
5q21-q22 |
Hs.432822 |
29 |
Golgi membrane in utero embryonic development liver development alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing mitochondrion organization vacuole organization respiratory gaseous exchange metabolic process zinc ion binding membrane integral to membrane hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding lung alveolus development |
N-Glycan biosynthesis Metabolic pathways |
206238_s_at |
0.603 |
6.316 |
3.846 |
1.550e-03 |
0.254 |
-0.971 |
YAF2 |
YY1 associated factor 2 |
12 |
-40837173 |
NM_005748 |
10138 |
12q12 |
Hs.708084 |
9 |
transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus zinc ion binding negative regulation of transcription positive regulation of transcription metal ion binding |
|
225895_at |
0.885 |
9.185 |
3.609 |
2.529e-03 |
0.287 |
-1.386 |
SYNPO2 |
synaptopodin 2 |
4 |
120029443, 120029443 |
AI634580 |
171024 |
4q26 |
Hs.655519 |
14 |
actin binding protein binding nucleus cytoplasm |
|
200928_s_at |
RAB14 |
RAB14, member RAS oncogene family |
9 |
-122980236 |
AL162081 |
51552 |
9q32-q34.11 |
Hs.371563 Hs.713585 |
19 |
nucleotide binding GTPase activity protein binding GTP binding intracellular membrane fraction lysosome early endosome late endosome rough endoplasmic reticulum Golgi stack cytosol plasma membrane Golgi to endosome transport small GTPase mediated signal transduction neurotransmitter secretion protein transport vesicle-mediated transport trans-Golgi network transport vesicle nuclear envelope-endoplasmic reticulum network intracellular transport perinuclear region of cytoplasm |
|
205029_s_at |
2.043 |
4.768 |
3.628 |
2.430e-03 |
0.284 |
-1.353 |
FABP7 |
fatty acid binding protein 7, brain |
6 |
123142344 |
NM_001446 |
2173 |
6q22-q23 |
Hs.26770 |
28 |
transporter activity cytoplasm transport nervous system development negative regulation of cell proliferation lipid binding |
PPAR signaling pathway |
209984_at |
0.401 |
5.759 |
3.924 |
1.321e-03 |
0.244 |
-0.836 |
KDM4C |
lysine (K)-specific demethylase 4C |
9 |
6710862, 6747640, 6747640, 6747640 |
AB037901 |
23081 |
9p24.1 |
Hs.709425 |
15 |
molecular_function nucleic acid binding iron ion binding protein binding cellular_component nucleus biological_process zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction |
|
200862_at |
1.025 |
7.125 |
2.975 |
9.329e-03 |
0.401 |
-2.497 |
DHCR24 |
24-dehydrocholesterol reductase |
1 |
-55087887 |
NM_014762 |
1718 |
1p33-p31.1 |
Hs.498727 |
25 |
nucleus endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus cholesterol biosynthetic process cholesterol biosynthetic process apoptosis anti-apoptosis response to oxidative stress cell cycle arrest protein localization tissue development membrane integral to membrane membrane organization oxidoreductase activity enzyme binding male genitalia development plasminogen activation peptide antigen binding amyloid precursor protein catabolic process negative regulation of caspase activity neuroprotection skin development delta24-sterol reductase activity FAD binding oxidation reduction |
Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
220116_at |
-0.486 |
6.122 |
-2.213 |
4.258e-02 |
0.576 |
-3.772 |
KCNN2 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 |
5 |
113725914, 113797125 |
NM_021614 |
3781 |
5q22.3 |
Hs.98280 |
15 |
ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity |
|
222713_s_at |
0.286 |
4.219 |
3.369 |
4.151e-03 |
0.324 |
-1.808 |
FANCF |
Fanconi anemia, complementation group F |
11 |
-22600654 |
AF181995 |
2188 |
11p15 |
Hs.713574 |
27 |
molecular_function protein binding cellular_component nucleus DNA repair response to DNA damage stimulus biological_process |
|
240453_at |
1.018 |
3.262 |
6.179 |
1.658e-05 |
0.076 |
2.741 |
C20orf26 |
chromosome 20 open reading frame 26 |
20 |
19981195 |
AA418538 |
26074 |
20p11.23 |
Hs.176013 |
6 |
|
|
212239_at |
0.527 |
7.454 |
2.322 |
3.448e-02 |
0.553 |
-3.597 |
PIK3R1 |
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
5 |
67558217, 67620007, 67622250 |
AI680192 |
5295 |
5q13.1 |
Hs.132225 Hs.604502 |
321 |
negative regulation of cell-matrix adhesion insulin receptor binding insulin-like growth factor receptor binding phosphatidylinositol binding intracellular cytosol cytosol 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex protein amino acid phosphorylation signal transduction insulin receptor signaling pathway phosphoinositide 3-kinase cascade membrane protein phosphatase binding B cell differentiation positive regulation of cell migration phosphoinositide 3-kinase regulator activity negative regulation of apoptosis ErbB-3 class receptor binding insulin binding insulin receptor substrate binding interspecies interaction between organisms negative regulation of osteoclast differentiation positive regulation of glucose import phosphoinositide phosphorylation insulin-like growth factor receptor signaling pathway growth hormone receptor signaling pathway regulation of establishment of protein localization |
ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer |
1569949_at |
1.580 |
8.496 |
5.790 |
3.373e-05 |
0.132 |
2.184 |
GRK5 |
G protein-coupled receptor kinase 5 |
10 |
120957186 |
BC018116 |
2869 |
10q24-qter |
Hs.524625 |
38 |
nucleotide binding G-protein coupled receptor kinase activity signal transducer activity protein kinase C binding protein binding ATP binding phospholipid binding soluble fraction cytoplasm plasma membrane protein amino acid phosphorylation signal transduction G-protein signaling, coupled to cAMP nucleotide second messenger tachykinin receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway transferase activity |
Chemokine signaling pathway Endocytosis |
228980_at |
0.745 |
6.188 |
3.387 |
3.998e-03 |
0.323 |
-1.776 |
RFFL |
ring finger and FYVE-like domain containing 1 |
17 |
-30360243, -30360243 |
AI760772 |
117584 |
17q12 |
Hs.13680 |
11 |
protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding |
|
217911_s_at |
0.602 |
10.389 |
5.130 |
1.180e-04 |
0.162 |
1.176 |
BAG3 |
BCL2-associated athanogene 3 |
10 |
121400871 |
NM_004281 |
9531 |
10q25.2-q26.2 |
Hs.523309 |
37 |
protein binding cellular_component cytosol protein folding anti-apoptosis |
|
227973_at |
0.570 |
6.770 |
3.006 |
8.750e-03 |
0.394 |
-2.443 |
C2orf69 |
chromosome 2 open reading frame 69 |
2 |
200484223 |
BF130937 |
205327 |
2q33.1 |
Hs.471040 |
3 |
extracellular region |
|
202917_s_at |
2.351 |
5.693 |
4.435 |
4.664e-04 |
0.193 |
0.041 |
S100A8 |
S100 calcium binding protein A8 |
1 |
-151629131 |
NM_002964 |
6279 |
1q21 |
Hs.416073 |
91 |
calcium ion binding protein binding inflammatory response |
|
228977_at |
1.392 |
7.946 |
3.940 |
1.278e-03 |
0.239 |
-0.807 |
LOC729680 |
hypothetical protein LOC729680 |
13 |
|
AI669535 |
729680 |
13q12.11 |
Hs.130652 |
1 |
|
|
210788_s_at |
0.626 |
10.280 |
3.609 |
2.529e-03 |
0.287 |
-1.387 |
DHRS7 |
dehydrogenase/reductase (SDR family) member 7 |
14 |
-59681251 |
AF126782 |
51635 |
14q23.1 |
Hs.59719 |
7 |
binding oxidoreductase activity oxidation reduction |
|
238974_at |
0.659 |
9.063 |
3.961 |
1.224e-03 |
0.234 |
-0.771 |
C2orf69 |
chromosome 2 open reading frame 69 |
2 |
200484223 |
N47077 |
205327 |
2q33.1 |
Hs.471040 |
3 |
extracellular region |
|
203021_at |
2.318 |
5.977 |
4.496 |
4.124e-04 |
0.192 |
0.143 |
SLPI |
secretory leukocyte peptidase inhibitor |
20 |
-43314292 |
NM_003064 |
6590 |
20q12 |
Hs.517070 |
71 |
serine-type endopeptidase inhibitor activity extracellular region |
|
205030_at |
2.457 |
6.423 |
3.137 |
6.696e-03 |
0.367 |
-2.215 |
FABP7 |
fatty acid binding protein 7, brain |
6 |
123142344 |
NM_001446 |
2173 |
6q22-q23 |
Hs.26770 |
28 |
transporter activity cytoplasm transport nervous system development negative regulation of cell proliferation lipid binding |
PPAR signaling pathway |
200653_s_at |
0.428 |
10.801 |
3.067 |
7.719e-03 |
0.380 |
-2.336 |
CALM1 |
calmodulin 1 (phosphorylase kinase, delta) |
14 |
89933125 |
M27319 |
801 |
14q24-q31 |
Hs.282410 Hs.708270 |
181 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
202492_at |
0.253 |
7.642 |
2.377 |
3.097e-02 |
0.542 |
-3.508 |
ATG9A |
ATG9 autophagy related 9 homolog A (S. cerevisiae) |
2 |
-219792345 |
NM_024085 |
79065 |
2q35 |
Hs.323363 |
10 |
autophagic vacuole formation autophagy protein transport membrane integral to membrane cytoplasmic vesicle |
|
240259_at |
1.527 |
5.668 |
5.306 |
8.395e-05 |
0.162 |
1.453 |
FLRT2 |
fibronectin leucine rich transmembrane protein 2 |
14 |
85066240 |
AI188161 |
23768 |
14q24-q32 |
Hs.533710 Hs.624735 Hs.719261 |
9 |
receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging |
|
226535_at |
-0.675 |
9.547 |
-4.470 |
4.352e-04 |
0.193 |
0.098 |
ITGB6 |
integrin, beta 6 |
2 |
-160666478 |
AK026736 |
3694 |
2q24.2 |
Hs.470399 |
44 |
receptor activity protein binding cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane interspecies interaction between organisms |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
226525_at |
0.828 |
5.070 |
5.114 |
1.216e-04 |
0.162 |
1.152 |
STK17B |
serine/threonine kinase 17b |
2 |
-196706552 |
N51102 |
9262 |
2q32.3 |
Hs.710234 Hs.88297 |
7 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade actin cytoskeleton transferase activity |
|
208937_s_at |
-0.636 |
8.418 |
-2.263 |
3.864e-02 |
0.567 |
-3.692 |
ID1 |
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
20 |
29656752 |
D13889 |
3397 |
20q11 |
Hs.504609 |
112 |
negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleus transforming growth factor beta receptor signaling pathway multicellular organismal development heart development negative regulation of transcription by transcription factor localization negative regulation of transcription transcription repressor activity BMP signaling pathway negative regulation of transcription factor activity blood vessel endothelial cell migration regulation of angiogenesis |
TGF-beta signaling pathway |
201106_at |
0.556 |
10.229 |
4.243 |
6.879e-04 |
0.211 |
-0.285 |
GPX4 |
glutathione peroxidase 4 (phospholipid hydroperoxidase) |
19 |
1054935, 1055648 |
NM_002085 |
2879 |
19p13.3 |
Hs.433951 |
50 |
glutathione peroxidase activity soluble fraction nucleus nuclear envelope cytoplasm mitochondrion mitochondrial inner membrane cytosol chromatin organization phospholipid metabolic process glutathione metabolic process response to oxidative stress multicellular organismal development spermatogenesis selenium binding oxidoreductase activity hydrogen peroxide catabolic process glutathione binding phospholipid-hydroperoxide glutathione peroxidase activity regulation of inflammatory response oxidation reduction |
Glutathione metabolism Arachidonic acid metabolism |
231969_at |
0.726 |
6.188 |
3.209 |
5.770e-03 |
0.357 |
-2.089 |
STOX2 |
storkhead box 2 |
4 |
185063502 |
AB037813 |
56977 |
4q35.1 |
Hs.21958 Hs.696657 |
3 |
|
|
224709_s_at |
0.351 |
6.971 |
2.773 |
1.406e-02 |
0.444 |
-2.845 |
CDC42SE2 |
CDC42 small effector 2 |
5 |
130627600 |
AF131831 |
56990 |
5q23.3-q31.1 |
Hs.508829 Hs.713870 |
8 |
structural molecule activity protein binding cytoplasm cytoskeleton plasma membrane phagocytosis regulation of cell shape regulation of signal transduction |
|
212742_at |
0.655 |
9.480 |
3.004 |
8.785e-03 |
0.394 |
-2.446 |
RNF115 |
ring finger protein 115 |
1 |
144322392 |
AL530462 |
27246 |
1q21.1 |
Hs.523550 |
8 |
protein binding zinc ion binding metal ion binding |
|
225192_at |
0.698 |
7.570 |
4.998 |
1.525e-04 |
0.171 |
0.967 |
C10orf46 |
chromosome 10 open reading frame 46 |
10 |
-120430483 |
AA044726 |
143384 |
10q26.11 |
Hs.719193 |
4 |
ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding |
|
203914_x_at |
0.828 |
5.134 |
3.783 |
1.765e-03 |
0.268 |
-1.081 |
HPGD |
hydroxyprostaglandin dehydrogenase 15-(NAD) |
4 |
-175647902, -175647902 |
NM_000860 |
3248 |
4q34-q35 |
Hs.596913 |
47 |
prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction |
|
212599_at |
AUTS2 |
autism susceptibility candidate 2 |
7 |
68701840, 68701841, 68701841 |
AK025298 |
26053 |
7q11.22 |
Hs.654801 Hs.712991 |
13 |
molecular_function cellular_component biological_process |
|
201681_s_at |
0.670 |
7.124 |
2.992 |
9.002e-03 |
0.396 |
-2.467 |
DLG5 |
discs, large homolog 5 (Drosophila) |
10 |
-79220554 |
AB011155 |
9231 |
10q23 |
Hs.652690 |
49 |
protein binding intracellular cytoplasm plasma membrane cell-cell adherens junction intracellular signaling cascade negative regulation of cell proliferation cell-cell adhesion cell junction receptor signaling complex scaffold activity regulation of apoptosis |
|
212297_at |
0.311 |
5.468 |
2.361 |
3.195e-02 |
0.545 |
-3.534 |
ATP13A3 |
ATPase type 13A3 |
3 |
-195604691 |
BF218804 |
79572 |
3q29 |
Hs.529609 |
11 |
nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity |
|
201393_s_at |
0.837 |
8.969 |
4.400 |
5.011e-04 |
0.201 |
-0.019 |
IGF2R |
insulin-like growth factor 2 receptor |
6 |
160310120 |
NM_000876 |
3482 |
6q26 |
Hs.487062 |
101 |
glycoprotein binding receptor activity insulin-like growth factor receptor activity transporter activity insulin-like growth factor binding mannose binding membrane fraction nucleus nuclear envelope lumen cytoplasm lysosome endosome Golgi apparatus integral to plasma membrane transport receptor-mediated endocytosis signal transduction membrane trans-Golgi network transport vesicle |
Lysosome |
210967_x_at |
0.303 |
9.549 |
2.885 |
1.120e-02 |
0.426 |
-2.653 |
CACNB1 |
calcium channel, voltage-dependent, beta 1 subunit |
17 |
-34586914, -34583234 |
M92301 |
782 |
17q21-q22 |
Hs.635 |
18 |
voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport |
MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
212765_at |
0.422 |
7.042 |
3.176 |
6.174e-03 |
0.361 |
-2.146 |
CAMSAP1L1 |
calmodulin regulated spectrin-associated protein 1-like 1 |
1 |
198975308 |
AB029001 |
23271 |
1q32.1 |
Hs.23585 |
6 |
|
|
204976_s_at |
0.486 |
5.380 |
3.981 |
1.174e-03 |
0.231 |
-0.736 |
AMMECR1 |
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
X |
-109324069 |
AK023637 |
9949 |
Xq22.3 |
Hs.656243 |
7 |
molecular_function cellular_component biological_process |
|
204094_s_at |
0.484 |
8.315 |
3.427 |
3.679e-03 |
0.314 |
-1.705 |
TSC22D2 |
TSC22 domain family, member 2 |
3 |
151609477 |
NM_014779 |
9819 |
3q25.1 |
Hs.665220 Hs.715600 |
5 |
transcription factor activity regulation of transcription, DNA-dependent |
|
228813_at |
0.918 |
8.494 |
3.799 |
1.706e-03 |
0.267 |
-1.053 |
HDAC4 |
histone deacetylase 4 |
2 |
-239634800 |
AW206037 |
9759 |
2q37.3 |
Hs.20516 Hs.688314 |
83 |
histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter skeletal system development DNA binding histone deacetylase activity nucleus cytoplasm inflammatory response cell cycle multicellular organismal development nervous system development transcription factor binding negative regulation of cell proliferation transcription repressor activity chromatin modification hydrolase activity B cell differentiation positive regulation of protein sumoylation negative regulation of striated muscle development |
|
227080_at |
0.565 |
5.638 |
3.428 |
3.672e-03 |
0.314 |
-1.704 |
ZNF697 |
zinc finger protein 697 |
1 |
-119963522 |
AW003092 |
90874 |
1p12 |
Hs.381105 Hs.711175 |
1 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
204175_at |
0.614 |
7.909 |
3.147 |
6.549e-03 |
0.365 |
-2.196 |
ZNF593 |
zinc finger protein 593 |
1 |
26368974 |
NM_015871 |
51042 |
1p36.11 |
Hs.477273 |
6 |
negative regulation of transcription from RNA polymerase II promoter DNA binding transcription corepressor activity intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding |
|
212565_at |
0.751 |
6.648 |
4.108 |
9.056e-04 |
0.220 |
-0.517 |
STK38L |
serine/threonine kinase 38 like |
12 |
27288344 |
BE302191 |
23012 |
12p11.23 |
Hs.184523 |
15 |
nucleotide binding magnesium ion binding actin binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation protein kinase cascade actin cytoskeleton transferase activity regulation of cellular component organization |
|
235815_at |
-0.285 |
3.830 |
-2.974 |
9.340e-03 |
0.401 |
-2.498 |
TSHZ2 |
teashirt zinc finger homeobox 2 |
20 |
51022283 |
BE222470 |
128553 |
20q13.2 |
Hs.271605 Hs.473117 Hs.649877 |
6 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding |
|
225833_at |
0.481 |
4.188 |
2.915 |
1.054e-02 |
0.418 |
-2.601 |
DAGLB |
diacylglycerol lipase, beta |
7 |
-6415272 |
BE795104 |
221955 |
7p22.1 |
Hs.487498 |
9 |
triacylglycerol lipase activity calcium ion binding plasma membrane integral to membrane lipid catabolic process hydrolase activity |
|
226653_at |
0.726 |
4.608 |
4.876 |
1.939e-04 |
0.172 |
0.769 |
MARK1 |
MAP/microtubule affinity-regulating kinase 1 |
1 |
218768190 |
AB040910 |
4139 |
1q41 |
Hs.497806 |
27 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm protein amino acid phosphorylation cytoskeleton organization protein kinase cascade microtubule cytoskeleton transferase activity |
|
212589_at |
0.635 |
8.264 |
4.253 |
6.738e-04 |
0.211 |
-0.268 |
RRAS2 |
related RAS viral (r-ras) oncogene homolog 2 |
11 |
-14256041, -14256041 |
AI753792 |
22800 |
11p15.2 |
Hs.502004 |
25 |
nucleotide binding GTPase activity protein binding GTP binding intracellular endoplasmic reticulum plasma membrane Ras protein signal transduction cellular process positive regulation of cell migration |
MAPK signaling pathway Tight junction Regulation of actin cytoskeleton |
238592_at |
PDLIM3 |
PDZ and LIM domain 3 |
4 |
-186659844 |
BE840636 |
27295 |
4q35 |
Hs.85862 |
12 |
nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding |
|
226989_at |
-1.180 |
7.030 |
-3.263 |
5.163e-03 |
0.347 |
-1.994 |
RGMB |
RGM domain family, member B |
5 |
98132898 |
BE855765 |
285704 |
5q15 |
Hs.526902 |
5 |
ER-Golgi intermediate compartment plasma membrane cell adhesion signal transduction BMP signaling pathway identical protein binding positive regulation of transcription anchored to plasma membrane |
|
228153_at |
0.566 |
9.778 |
3.326 |
4.536e-03 |
0.332 |
-1.884 |
RNF144B |
ring finger protein 144B |
6 |
18495572 |
AI953847 |
255488 |
6p22.3 |
Hs.148741 |
6 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding |
|
220949_s_at |
0.431 |
7.049 |
3.212 |
5.734e-03 |
0.357 |
-2.083 |
C7orf49 |
chromosome 7 open reading frame 49 |
7 |
-134501071 |
NM_024033 |
78996 |
7q33 |
Hs.521213 |
4 |
cytoplasm |
|
215167_at |
-1.082 |
6.711 |
-4.184 |
7.760e-04 |
0.211 |
-0.387 |
MED14 |
mediator complex subunit 14 |
X |
-40393738 |
BE567032 |
9282 |
Xp11.4-p11.2 |
Hs.407604 |
33 |
receptor activity protein binding nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding |
|
1555487_a_at |
0.203 |
5.670 |
2.353 |
3.250e-02 |
0.547 |
-3.548 |
ACTR3B |
ARP3 actin-related protein 3 homolog B (yeast) |
7 |
152087783 |
BC015207 |
57180 |
7q36.1 |
Hs.647117 |
8 |
nucleotide binding actin binding protein binding ATP binding cytoplasm cytoskeleton regulation of actin filament polymerization cell projection |
|
203693_s_at |
0.377 |
6.387 |
2.726 |
1.548e-02 |
0.458 |
-2.926 |
E2F3 |
E2F transcription factor 3 |
6 |
20510115 |
NM_001949 |
1871 |
6p22 |
Hs.269408 Hs.703174 |
48 |
transcription factor activity protein binding nucleus nucleoplasm transcription factor complex regulation of transcription, DNA-dependent transcription initiation from RNA polymerase II promoter cell cycle |
Cell cycle Pathways in cancer Pancreatic cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer |
235132_at |
0.642 |
6.248 |
4.902 |
1.842e-04 |
0.171 |
0.811 |
LOC254128 |
hypothetical protein LOC254128 |
2 |
|
BF939830 |
254128 |
2q14.2 |
Hs.712685 |
1 |
|
|
201724_s_at |
0.306 |
6.968 |
2.634 |
1.861e-02 |
0.486 |
-3.081 |
GALNT1 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) |
18 |
31488530 |
NM_020474 |
2589 |
18q12.1 |
Hs.514806 |
26 |
polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding extracellular region Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups protein amino acid O-linked glycosylation via serine protein amino acid O-linked glycosylation via threonine manganese ion binding perinuclear region of cytoplasm |
O-Glycan biosynthesis Metabolic pathways |
218618_s_at |
0.892 |
5.976 |
4.500 |
4.092e-04 |
0.192 |
0.150 |
FNDC3B |
fibronectin type III domain containing 3B |
3 |
173240111, 173241037 |
NM_022763 |
64778 |
3q26.31 |
Hs.159430 |
9 |
endoplasmic reticulum membrane integral to membrane |
|
220359_s_at |
1.814 |
4.646 |
4.195 |
7.596e-04 |
0.211 |
-0.369 |
ARPP-21 |
cyclic AMP-regulated phosphoprotein, 21 kD |
3 |
35658852, 35696119, 35697432 |
NM_016300 |
10777 |
3p22.3 |
Hs.475902 Hs.713605 |
7 |
molecular_function nucleic acid binding cellular_component cytoplasm biological_process |
|
1556114_a_at |
0.902 |
9.046 |
4.948 |
1.681e-04 |
0.171 |
0.887 |
DKFZp451A211 |
DKFZp451A211 protein |
13 |
|
BC036906 |
400169 |
13q34 |
Hs.646609 |
1 |
|
|
65630_at |
0.563 |
6.360 |
4.086 |
9.469e-04 |
0.223 |
-0.554 |
TMEM80 |
transmembrane protein 80 |
11 |
685615 |
AI742455 |
283232 |
11p15.5 |
Hs.448664 |
2 |
membrane integral to membrane |
|
232172_at |
0.316 |
4.887 |
2.912 |
1.061e-02 |
0.418 |
-2.607 |
LOC401577 |
hypothetical protein LOC401577 |
X, Y |
|
AK023533 |
401577 |
Xp22.33 Yp11.31 |
Hs.444541 |
2 |
|
|
223168_at |
0.728 |
8.352 |
3.769 |
1.818e-03 |
0.270 |
-1.106 |
RHOU |
ras homolog gene family, member U |
1 |
226937491 |
AL096776 |
58480 |
1q42.11-q42.3 |
Hs.647774 |
12 |
G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding podosome GTPase activity protein binding GTP binding intracellular Golgi apparatus plasma membrane focal adhesion small GTPase mediated signal transduction regulation of cell shape Rac protein signal transduction actin cytoskeleton organization cell junction cell projection |
|
204156_at |
QSK |
serine/threonine-protein kinase QSK |
11 |
-116219327 |
AA044154 |
23387 |
11q23.3 |
Hs.167451 |
14 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
217716_s_at |
0.354 |
6.988 |
3.324 |
4.552e-03 |
0.332 |
-1.887 |
SEC61A1 |
Sec61 alpha 1 subunit (S. cerevisiae) |
3 |
129253901 |
NM_013336 |
29927 |
3q21.3 |
Hs.518236 |
14 |
protein binding endoplasmic reticulum protein transport P-P-bond-hydrolysis-driven protein transmembrane transporter activity membrane integral to membrane ribosome binding intracellular protein transmembrane transport |
Vibrio cholerae infection |
206996_x_at |
0.248 |
9.524 |
2.364 |
3.179e-02 |
0.544 |
-3.530 |
CACNB1 |
calcium channel, voltage-dependent, beta 1 subunit |
17 |
-34586914, -34583234 |
NM_000723 |
782 |
17q21-q22 |
Hs.635 |
18 |
voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport |
MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
201586_s_at |
0.324 |
7.590 |
3.149 |
6.529e-03 |
0.364 |
-2.194 |
SFPQ |
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) |
1 |
-35421789 |
NM_005066 |
6421 |
1p34.3 |
Hs.355934 |
47 |
nucleotide binding DNA binding RNA binding protein binding nucleus DNA repair DNA recombination mRNA processing response to DNA damage stimulus RNA splicing nuclear matrix regulation of transcription |
|
205003_at |
-0.288 |
7.291 |
-2.478 |
2.541e-02 |
0.515 |
-3.343 |
DOCK4 |
dedicator of cytokinesis 4 |
7 |
-111153399 |
NM_014705 |
9732 |
7q31.1 |
Hs.654652 |
16 |
guanyl-nucleotide exchange factor activity protein binding membrane SH3 domain binding PDZ domain binding Rac GTPase activator activity stereocilium Rac GTPase binding |
|
37996_s_at |
0.629 |
6.701 |
3.102 |
7.192e-03 |
0.374 |
-2.276 |
DMPK |
dystrophia myotonica-protein kinase |
19 |
-50964815, -50964815 |
L08835 |
1760 |
19q13.3 |
Hs.631596 |
91 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein modification process protein amino acid phosphorylation regulation of heart contraction transferase activity |
|
225731_at |
0.492 |
5.190 |
3.511 |
3.093e-03 |
0.302 |
-1.558 |
ANKRD50 |
ankyrin repeat domain 50 |
4 |
-125804915 |
BF196876 |
57182 |
4q28.1 |
Hs.480694 |
3 |
|
|
1555259_at |
0.435 |
5.978 |
2.420 |
2.850e-02 |
0.532 |
-3.439 |
ZAK |
sterile alpha motif and leucine zipper containing kinase AZK |
2 |
173648810, 173648810 |
AF465843 |
51776 |
2q24.2 |
Hs.444451 |
24 |
cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis |
MAPK signaling pathway Tight junction |
211652_s_at |
2.064 |
4.811 |
4.239 |
6.936e-04 |
0.211 |
-0.292 |
LBP |
lipopolysaccharide binding protein |
20 |
36408298 |
M35533 |
3929 |
20q11.23-q12 |
Hs.154078 |
58 |
lipopolysaccharide binding macrophage activation during immune response receptor binding extracellular region extracellular region extracellular space extracellular space nucleus lipid transport acute-phase response acute-phase response cellular defense response opsonization opsonization lipid binding lipopolysaccharide transport lipopolysaccharide-mediated signaling pathway detection of molecule of bacterial origin response to lipopolysaccharide negative regulation of tumor necrosis factor production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 4 signaling pathway positive regulation of macrophage activation cell surface binding innate immune response innate immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium Gram-negative bacterial cell surface binding Gram-negative bacterial cell surface binding Gram-positive bacterial cell surface binding positive regulation of respiratory burst during acute inflammatory response |
Toll-like receptor signaling pathway |
219353_at |
0.390 |
7.093 |
2.214 |
4.249e-02 |
0.575 |
-3.770 |
NHLRC2 |
NHL repeat containing 2 |
10 |
115604409 |
NM_017687 |
374354 |
10q25.3 |
Hs.369924 Hs.594372 |
2 |
cell redox homeostasis |
|
209286_at |
1.202 |
6.516 |
3.551 |
2.849e-03 |
0.296 |
-1.488 |
CDC42EP3 |
CDC42 effector protein (Rho GTPase binding) 3 |
2 |
-37724246 |
AI754416 |
10602 |
2p21 |
Hs.369574 |
17 |
protein binding cytoskeletal regulatory protein binding cytoplasm signal transduction regulation of cell shape actin cytoskeleton membrane |
|
223169_s_at |
0.644 |
5.662 |
4.214 |
7.298e-04 |
0.211 |
-0.335 |
RHOU |
ras homolog gene family, member U |
1 |
226937491 |
AB051826 |
58480 |
1q42.11-q42.3 |
Hs.647774 |
12 |
G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding podosome GTPase activity protein binding GTP binding intracellular Golgi apparatus plasma membrane focal adhesion small GTPase mediated signal transduction regulation of cell shape Rac protein signal transduction actin cytoskeleton organization cell junction cell projection |
|
218273_s_at |
-1.333 |
7.566 |
-4.439 |
4.629e-04 |
0.193 |
0.047 |
PDP1 |
pyruvate dehyrogenase phosphatase catalytic subunit 1 |
8 |
94998258, 94998337, 94998350, 94998454, 94999167 |
NM_018444 |
54704 |
8q22.1 |
Hs.22265 |
19 |
magnesium ion binding protein serine/threonine phosphatase activity [pyruvate dehydrogenase (lipoamide)] phosphatase activity calcium ion binding mitochondrion mitochondrial matrix protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity |
|
224865_at |
FAR1 |
fatty acyl CoA reductase 1 |
11 |
13646781 |
N63551 |
84188 |
11p15.2 |
Hs.501991 |
10 |
protein binding peroxisome lipid biosynthetic process membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor oxidation reduction |
|
233919_s_at |
0.219 |
6.234 |
2.288 |
3.685e-02 |
0.561 |
-3.652 |
HABP4 |
hyaluronan binding protein 4 |
9 |
98252234 |
BF213501 |
22927 |
9q22.3-q31 |
Hs.494567 |
15 |
nucleus cytoplasm regulation of transcription |
|
1565389_s_at |
-0.369 |
5.042 |
-4.450 |
4.527e-04 |
0.193 |
0.065 |
GRM5 |
glutamate receptor, metabotropic 5 |
11 |
-87877392, -87877392 |
S64316 |
2915 |
11q14.2-q14.3 |
Hs.147361 Hs.680431 Hs.719168 |
33 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway synaptic transmission glutamate receptor activity |
Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction Long-term potentiation Long-term depression Huntington's disease |
226563_at |
0.523 |
6.864 |
4.397 |
5.034e-04 |
0.201 |
-0.023 |
SMAD2 |
SMAD family member 2 |
18 |
-43613464, -43613463, -43613463 |
BF793454 |
4087 |
18q21.1 |
Hs.12253 Hs.705764 |
206 |
mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol |
Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer |
212993_at |
NACC2 |
NACC family member 2, BEN and BTB (POZ) domain containing |
9 |
-138043023 |
AA114166 |
138151 |
9q34.3 |
Hs.112895 |
3 |
protein binding nucleus positive regulation of cell proliferation negative regulation of transcription specific transcriptional repressor activity nuclear body protein homooligomerization |
|
242029_at |
0.504 |
6.163 |
4.334 |
5.729e-04 |
0.211 |
-0.132 |
FNDC3B |
fibronectin type III domain containing 3B |
3 |
173240111, 173241037 |
N32832 |
64778 |
3q26.31 |
Hs.159430 |
9 |
endoplasmic reticulum membrane integral to membrane |
|
204476_s_at |
0.631 |
5.336 |
3.990 |
1.155e-03 |
0.231 |
-0.722 |
PC |
pyruvate carboxylase |
11 |
-66372572, -66372572 |
NM_022172 |
5091 |
11q13.4-q13.5 |
Hs.89890 |
26 |
nucleotide binding pyruvate carboxylase activity pyruvate carboxylase activity ATP binding soluble fraction cytoplasm mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial matrix gluconeogenesis oxaloacetate metabolic process metabolic process lipid biosynthetic process biotin binding ligase activity manganese ion binding carboxylic acid binding metal ion binding |
Citrate cycle (TCA cycle) Pyruvate metabolism Metabolic pathways |
233814_at |
-0.262 |
4.042 |
-2.264 |
3.862e-02 |
0.567 |
-3.691 |
EFNA5 |
ephrin-A5 |
5 |
-106740488 |
AK025909 |
1946 |
5q21 |
Hs.288741 |
27 |
protein binding extracellular space plasma membrane cell-cell signaling multicellular organismal development nervous system development cell differentiation anchored to plasma membrane ephrin receptor binding |
Axon guidance |
215102_at |
0.401 |
4.330 |
3.583 |
2.667e-03 |
0.290 |
-1.432 |
DPY19L1P1 |
dpy-19-like 1 pseudogene 1 (C. elegans) |
7 |
|
AK026768 |
100129460 |
7p14.3 |
Hs.633705 |
|
|
|
234317_s_at |
0.596 |
5.728 |
3.703 |
2.083e-03 |
0.275 |
-1.222 |
STOX2 |
storkhead box 2 |
4 |
185063502 |
AL390216 |
56977 |
4q35.1 |
Hs.21958 Hs.696657 |
3 |
|
|
217359_s_at |
0.754 |
3.700 |
3.202 |
5.855e-03 |
0.357 |
-2.101 |
NCAM1 |
neural cell adhesion molecule 1 |
11 |
112337204, 112337204 |
M22094 |
4684 |
11q23.1 |
Hs.503878 |
120 |
protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane |
Cell adhesion molecules (CAMs) Prion diseases |
224281_s_at |
0.464 |
9.795 |
4.432 |
4.695e-04 |
0.193 |
0.035 |
NGRN |
neugrin, neurite outgrowth associated |
15 |
88609898 |
AF225423 |
51335 |
15q26.1 |
Hs.715556 Hs.716378 |
2 |
molecular_function nucleus multicellular organismal development nervous system development neuron differentiation |
|
228594_at |
-0.451 |
7.140 |
-5.045 |
1.391e-04 |
0.169 |
1.042 |
C5orf33 |
chromosome 5 open reading frame 33 |
5 |
-36228450, -36228450 |
H94910 |
133686 |
5p13.2 |
Hs.81907 |
3 |
NAD+ kinase activity metabolic process |
|
222656_at |
1.010 |
6.165 |
4.109 |
9.044e-04 |
0.220 |
-0.516 |
UBE2W |
ubiquitin-conjugating enzyme E2W (putative) |
8 |
-74865393 |
AI625741 |
55284 |
8q21.11 |
Hs.597486 |
7 |
nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
212585_at |
0.647 |
7.101 |
3.426 |
3.684e-03 |
0.314 |
-1.707 |
OSBPL8 |
oxysterol binding protein-like 8 |
12 |
-75269708 |
BF970829 |
114882 |
12q14 |
Hs.430849 |
13 |
lipid transport steroid metabolic process |
|
227406_at |
0.618 |
6.757 |
3.816 |
1.649e-03 |
0.263 |
-1.023 |
LOC100129387 |
hypothetical LOC100129387 |
15 |
48433662 |
AI286203 |
100129387 |
15q21.2 |
Hs.659360 |
1 |
|
|
243009_at |
-0.734 |
5.692 |
-4.912 |
1.805e-04 |
0.171 |
0.828 |
LOC441242 |
hypothetical LOC441242 |
7 |
|
AW513654 |
441242 |
7q11.21 |
Hs.656146 |
2 |
|
|
209563_x_at |
0.531 |
11.120 |
4.206 |
7.427e-04 |
0.211 |
-0.350 |
CALM1 |
calmodulin 1 (phosphorylase kinase, delta) |
14 |
89933125 |
BC000454 |
801 |
14q24-q31 |
Hs.282410 Hs.708270 |
181 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
205335_s_at |
0.346 |
8.585 |
3.573 |
2.720e-03 |
0.290 |
-1.449 |
SRP19 |
signal recognition particle 19kDa |
5 |
112224891 |
NM_003135 |
6728 |
5q21-q22 |
Hs.637001 |
14 |
nucleolus cytoplasm signal recognition particle, endoplasmic reticulum targeting SRP-dependent cotranslational protein targeting to membrane 7S RNA binding response to drug |
Protein export |
244572_at |
-0.981 |
7.073 |
-3.634 |
2.399e-03 |
0.284 |
-1.342 |
KY |
kyphoscoliosis peptidase |
3 |
-135801454 |
AI147310 |
339855 |
3q22.2 |
Hs.146730 |
4 |
cytoplasm cytoskeleton peptidase activity |
|
212791_at |
C1orf216 |
chromosome 1 open reading frame 216 |
1 |
-35952063 |
AL042729 |
127703 |
1p34.3 |
Hs.112023 |
3 |
|
|
232183_at |
SERAC1 |
serine active site containing 1 |
6 |
-158450523 |
AA128978 |
84947 |
6q25.3 |
Hs.154706 |
6 |
binding membrane integral to membrane |
|
242056_at |
0.645 |
7.261 |
4.665 |
2.941e-04 |
0.175 |
0.425 |
TRIM45 |
tripartite motif-containing 45 |
1 |
-117455199 |
AI793200 |
80263 |
1p13.1 |
Hs.301526 |
8 |
protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding |
|
1555882_at |
1.306 |
3.612 |
4.568 |
3.572e-04 |
0.183 |
0.263 |
SPIN3 |
spindlin family, member 3 |
X |
-57033988, -57019529 |
AJ271379 |
169981 |
Xp11.21 |
Hs.522672 |
6 |
gamete generation |
|
220201_at |
0.425 |
5.261 |
3.537 |
2.935e-03 |
0.298 |
-1.513 |
RC3H2 |
ring finger and CCCH-type zinc finger domains 2 |
9 |
-124655844, -124651552 |
NM_018835 |
54542 |
9q34 |
Hs.533499 |
6 |
DNA binding protein binding membrane fraction cytoplasm biological_process zinc ion binding cell surface membrane metal ion binding perinuclear region of cytoplasm |
|
209612_s_at |
ADH1B |
alcohol dehydrogenase 1B (class I), beta polypeptide |
4 |
-100446549 |
M24317 |
125 |
4q21-q23 |
Hs.4 |
193 |
alcohol dehydrogenase (NAD) activity binding cytoplasm ethanol oxidation zinc ion binding oxidoreductase activity metal ion binding oxidation reduction |
Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways |
226280_at |
0.422 |
8.481 |
3.599 |
2.578e-03 |
0.287 |
-1.403 |
BNIP2 |
BCL2/adenovirus E1B 19kDa interacting protein 2 |
15 |
-57742353 |
AA133277 |
663 |
15q22.2 |
Hs.646490 |
15 |
GTPase activator activity calcium ion binding protein binding nuclear envelope cytoplasm apoptosis anti-apoptosis intracellular membrane-bounded organelle perinuclear region of cytoplasm |
|
225057_at |
0.514 |
7.770 |
3.007 |
8.743e-03 |
0.394 |
-2.442 |
SLC15A4 |
solute carrier family 15, member 4 |
12 |
-127843692 |
AI636759 |
121260 |
12q24.32-q24.33 |
Hs.507260 Hs.699387 |
6 |
transporter activity oligopeptide transport protein transport symporter activity membrane integral to membrane |
|
224758_at |
0.299 |
4.495 |
2.474 |
2.561e-02 |
0.517 |
-3.350 |
PL-5283 |
PL-5283 protein |
7 |
134997760 |
BG393032 |
647087 |
7q33 |
Hs.200022 |
3 |
|
|
210993_s_at |
0.754 |
7.248 |
4.919 |
1.781e-04 |
0.171 |
0.839 |
SMAD1 |
SMAD family member 1 |
4 |
146622400, 146623406 |
U54826 |
4086 |
4q31 |
Hs.604588 |
118 |
MAPKKK cascade mesodermal cell fate commitment osteoblast fate commitment transcription factor activity RNA polymerase II transcription factor activity receptor signaling protein activity intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol inflammatory response signal transduction transforming growth factor beta receptor signaling pathway SMAD protein complex assembly gamete generation negative regulation of cell proliferation embryonic pattern specification positive regulation of gene expression integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity midbrain development hindbrain development primary microRNA processing homeostatic process identical protein binding positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter co-SMAD binding |
TGF-beta signaling pathway |
1560018_at |
ARPP-21 |
cyclic AMP-regulated phosphoprotein, 21 kD |
3 |
35658852, 35696119, 35697432 |
H44077 |
10777 |
3p22.3 |
Hs.475902 Hs.713605 |
7 |
molecular_function nucleic acid binding cellular_component cytoplasm biological_process |
|
209287_s_at |
0.492 |
6.135 |
4.369 |
5.333e-04 |
0.207 |
-0.072 |
CDC42EP3 |
CDC42 effector protein (Rho GTPase binding) 3 |
2 |
-37724246 |
AF104857 |
10602 |
2p21 |
Hs.369574 |
17 |
protein binding cytoskeletal regulatory protein binding cytoplasm signal transduction regulation of cell shape actin cytoskeleton membrane |
|
224898_at |
0.524 |
5.465 |
3.093 |
7.321e-03 |
0.376 |
-2.291 |
WDR26 |
WD repeat domain 26 |
1 |
-222639467 |
BG177759 |
80232 |
1q42.11-q42.12 |
Hs.497873 |
8 |
cytoplasm |
|
214033_at |
0.400 |
5.924 |
2.717 |
1.575e-02 |
0.459 |
-2.941 |
ABCC6 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
16 |
-16222544, -16150922 |
AI084637 |
368 |
16p13.1 |
Hs.442182 |
70 |
nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus |
ABC transporters |
221232_s_at |
ANKRD2 |
ankyrin repeat domain 2 (stretch responsive muscle) |
10 |
99322245 |
NM_020349 |
26287 |
10q23.31-q23.32 |
Hs.73708 |
17 |
muscle organ development structural constituent of muscle I band |
|
235070_at |
0.633 |
8.267 |
4.836 |
2.095e-04 |
0.172 |
0.705 |
A2BP1 |
ataxin 2-binding protein 1 |
16 |
6009132, 6763810, 7322751 |
AL133898 |
54715 |
16p13.3 |
Hs.459842 |
22 |
nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport |
|
215903_s_at |
0.312 |
8.195 |
2.841 |
1.225e-02 |
0.427 |
-2.729 |
MAST2 |
microtubule associated serine/threonine kinase 2 |
1 |
46041871 |
BE786598 |
23139 |
1p34.1 |
Hs.319481 |
19 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoskeleton plasma membrane protein amino acid phosphorylation transferase activity phosphatase binding regulation of interleukin-12 biosynthetic process spermatid differentiation |
|
218829_s_at |
CHD7 |
chromodomain helicase DNA binding protein 7 |
8 |
61753892 |
NM_017780 |
55636 |
8q12.1-q12.2 |
Hs.20395 |
36 |
nucleotide binding chromatin skeletal system development blood vessel development in utero embryonic development heart morphogenesis DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly central nervous system development adult heart development sensory perception of sound locomotory behavior adult walking behavior blood circulation chromatin modification hydrolase activity cranial nerve development T cell differentiation female genitalia development embryonic hindlimb morphogenesis positive regulation of multicellular organism growth inner ear morphogenesis nose development regulation of transcription cognition palate development retina development in camera-type eye regulation of growth hormone secretion limb development face development |
|
212843_at |
0.943 |
5.000 |
3.774 |
1.799e-03 |
0.270 |
-1.098 |
NCAM1 |
neural cell adhesion molecule 1 |
11 |
112337204, 112337204 |
AA126505 |
4684 |
11q23.1 |
Hs.503878 |
120 |
protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane |
Cell adhesion molecules (CAMs) Prion diseases |
219806_s_at |
0.702 |
5.718 |
3.893 |
1.407e-03 |
0.247 |
-0.889 |
C11orf75 |
chromosome 11 open reading frame 75 |
11 |
-92851286 |
NM_020179 |
56935 |
11q13.3-q23.3 |
Hs.438064 |
3 |
molecular_function cellular_component biological_process membrane integral to membrane |
|
1555960_at |
0.583 |
4.400 |
3.904 |
1.376e-03 |
0.245 |
-0.870 |
HINT1 |
histidine triad nucleotide binding protein 1 |
5 |
-130522773, -130522773 |
AK054976 |
3094 |
5q31.2 |
Hs.483305 |
26 |
protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity |
|
232000_at |
1.178 |
3.038 |
4.996 |
1.532e-04 |
0.171 |
0.963 |
TTC39B |
tetratricopeptide repeat domain 39B |
9 |
-15161560 |
AW001030 |
158219 |
9p22.3 |
Hs.563630 |
3 |
binding |
|
216115_at |
0.353 |
5.019 |
3.489 |
3.239e-03 |
0.306 |
-1.597 |
NF1 |
neurofibromin 1 |
17 |
26446120, 26446120 |
AK024873 |
4763 |
17q11.2 |
Hs.113577 |
204 |
osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction |
MAPK signaling pathway |
226380_at |
0.379 |
6.509 |
2.831 |
1.252e-02 |
0.429 |
-2.747 |
PTPN21 |
protein tyrosine phosphatase, non-receptor type 21 |
14 |
-88001874 |
N21442 |
11099 |
14q31.3 |
Hs.437040 |
10 |
protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity |
|
1556536_at |
-0.351 |
3.835 |
-3.690 |
2.140e-03 |
0.276 |
-1.245 |
hCG_2044152 |
hCG2044152 |
2 |
|
BC040292 |
729224 |
2q33.1 |
Hs.623895 |
1 |
|
|
213005_s_at |
0.478 |
8.042 |
4.258 |
6.675e-04 |
0.211 |
-0.260 |
KANK1 |
KN motif and ankyrin repeat domains 1 |
9 |
494702, 696895 |
D79994 |
23189 |
9p24.3 |
Hs.306764 |
14 |
cytoplasm |
|
235146_at |
TMCC3 |
transmembrane and coiled-coil domain family 3 |
12 |
-93485030 |
N51717 |
57458 |
12q22 |
Hs.370410 |
5 |
membrane integral to membrane |
|
203269_at |
0.337 |
8.020 |
3.461 |
3.430e-03 |
0.308 |
-1.646 |
NSMAF |
neutral sphingomyelinase (N-SMase) activation associated factor |
8 |
-59658619, -59658619 |
NM_003580 |
8439 |
8q12-q13 |
Hs.372000 |
8 |
receptor signaling protein activity soluble fraction cytoplasm ceramide metabolic process signal transduction |
|
212510_at |
-0.504 |
10.561 |
-3.746 |
1.906e-03 |
0.273 |
-1.147 |
GPD1L |
glycerol-3-phosphate dehydrogenase 1-like |
3 |
32123147 |
AA135522 |
23171 |
3p22.3 |
Hs.82432 |
5 |
glycerol-3-phosphate dehydrogenase (NAD+) activity binding cytoplasm carbohydrate metabolic process glycerol-3-phosphate dehydrogenase complex protein homodimerization activity glycerol-3-phosphate catabolic process NAD or NADH binding oxidation reduction |
Glycerophospholipid metabolism |
228702_at |
0.643 |
7.814 |
2.210 |
4.281e-02 |
0.576 |
-3.776 |
FLJ43663 |
hypothetical LOC378805 |
7 |
-130279458, -130279458 |
AL569506 |
378805 |
7q32.3 |
Hs.150556 Hs.649308 |
2 |
|
|
36030_at |
0.484 |
6.822 |
2.588 |
2.042e-02 |
0.495 |
-3.159 |
IFFO1 |
intermediate filament family orphan 1 |
12 |
-6518954, -6518954 |
AL080214 |
25900 |
12p13.3 |
Hs.15243 |
7 |
intermediate filament |
|
219284_at |
-0.879 |
7.040 |
-4.254 |
6.732e-04 |
0.211 |
-0.267 |
HSPBAP1 |
HSPB (heat shock 27kDa) associated protein 1 |
3 |
-123941535 |
NM_024610 |
79663 |
3q21.1 |
Hs.29169 |
5 |
cytoplasm |
|
227257_s_at |
C10orf46 |
chromosome 10 open reading frame 46 |
10 |
-120430483 |
AW973842 |
143384 |
10q26.11 |
Hs.719193 |
4 |
ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding |
|
221511_x_at |
0.486 |
7.859 |
3.862 |
1.499e-03 |
0.251 |
-0.943 |
CCPG1 |
cell cycle progression 1 |
15 |
-53434729, -53434729 |
AB033080 |
9236 |
15q21.1 |
Hs.285051 |
5 |
cell cycle membrane integral to membrane |
|
238890_at |
PSMG1 |
proteasome (prosome, macropain) assembly chaperone 1 |
21 |
-39469253 |
AI791303 |
8624 |
21q22.3 |
Hs.473838 |
12 |
protein binding cytoplasm endoplasmic reticulum proteasome assembly |
|
222423_at |
0.291 |
7.461 |
2.429 |
2.798e-02 |
0.529 |
-3.423 |
NDFIP1 |
Nedd4 family interacting protein 1 |
5 |
141468507 |
H05010 |
80762 |
5q31.3 |
Hs.653510 Hs.9788 |
11 |
signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport |
|
225032_at |
0.716 |
8.203 |
4.245 |
6.858e-04 |
0.211 |
-0.283 |
FNDC3B |
fibronectin type III domain containing 3B |
3 |
173240111, 173241037 |
AI141784 |
64778 |
3q26.31 |
Hs.159430 |
9 |
endoplasmic reticulum membrane integral to membrane |
|
208817_at |
0.413 |
7.854 |
2.457 |
2.647e-02 |
0.522 |
-3.377 |
COMT |
catechol-O-methyltransferase |
22 |
18309262, 18318459, 18319044, 18330069 |
BC000419 |
1312 |
22q11.21 22q11.21-q11.23 |
Hs.370408 Hs.704514 Hs.713616 |
742 |
magnesium ion binding protein binding soluble fraction cytoplasm microsome cytosol plasma membrane catecholamine metabolic process integral to membrane catechol O-methyltransferase activity catechol O-methyltransferase activity transferase activity neurotransmitter catabolic process dopamine catabolic process |
Tyrosine metabolism Betalain biosynthesis Metabolic pathways |
225985_at |
0.329 |
4.297 |
3.610 |
2.520e-03 |
0.287 |
-1.384 |
PRKAA1 |
protein kinase, AMP-activated, alpha 1 catalytic subunit |
5 |
-40795237 |
AI935917 |
5562 |
5p12 |
Hs.43322 |
68 |
nucleotide binding activation of MAPK activity magnesium ion binding response to hypoxia protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein binding ATP binding intracellular glucose metabolic process fatty acid biosynthetic process signal transduction transferase activity fatty acid oxidation positive regulation of cholesterol biosynthetic process positive regulation of anti-apoptosis negative regulation of glucosylceramide biosynthetic process |
Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM) |
203544_s_at |
0.361 |
7.175 |
2.457 |
2.648e-02 |
0.522 |
-3.378 |
STAM |
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
10 |
17726129 |
NM_003473 |
8027 |
10p14-p13 |
Hs.441498 |
30 |
SH3/SH2 adaptor activity protein binding cytoplasm endosome cytosol intracellular protein transport signal transduction membrane |
Endocytosis Jak-STAT signaling pathway |
228555_at |
0.409 |
6.532 |
2.854 |
1.194e-02 |
0.426 |
-2.706 |
CAMK2D |
calcium/calmodulin-dependent protein kinase II delta |
4 |
-114597792, -114591638 |
AA029441 |
817 |
4q26 |
Hs.144114 |
29 |
G1/S transition of mitotic cell cycle nucleotide binding regulation of cell growth calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm calcium- and calmodulin-dependent protein kinase complex calcium ion transport transferase activity T-tubule protein amino acid autophosphorylation cardiac muscle contraction |
ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma |
212877_at |
0.618 |
7.090 |
3.931 |
1.301e-03 |
0.242 |
-0.823 |
KLC1 |
kinesin light chain 1 |
14 |
103165277, 103165277 |
AA284075 |
3831 |
14q32.3 |
Hs.20107 Hs.657678 |
31 |
microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle |
|
221753_at |
SSH1 |
slingshot homolog 1 (Drosophila) |
12 |
-107709824, -107709824, -107700595 |
AI651213 |
54434 |
12q24.11 |
Hs.199763 |
23 |
cell morphogenesis actin binding protein tyrosine phosphatase activity protein binding cytoplasm cytoskeleton plasma membrane protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity lamellipodium actin cytoskeleton organization |
Regulation of actin cytoskeleton |
238034_at |
0.333 |
6.690 |
2.364 |
3.178e-02 |
0.544 |
-3.530 |
CANX |
calnexin |
5 |
179058535 |
AI890021 |
821 |
5q35 |
Hs.699155 |
90 |
calcium ion binding sugar binding endoplasmic reticulum protein folding protein secretion membrane integral to membrane melanosome unfolded protein binding |
Antigen processing and presentation |
225300_at |
0.675 |
6.369 |
4.445 |
4.570e-04 |
0.193 |
0.057 |
C15orf23 |
chromosome 15 open reading frame 23 |
15 |
38462213 |
BF792864 |
90417 |
15q15.1 |
Hs.525796 |
6 |
protein binding nucleus |
|
220123_at |
0.841 |
3.457 |
3.226 |
5.576e-03 |
0.354 |
-2.059 |
SLC35F5 |
solute carrier family 35, member F5 |
2 |
-114188402 |
NM_025181 |
80255 |
2q14.1 |
Hs.632527 |
2 |
transport membrane integral to membrane |
|
226922_at |
RANBP2 |
RAN binding protein 2 |
2 |
108702368 |
BF215302 |
5903 |
2q12.3 |
Hs.199561 Hs.715056 |
61 |
peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport |
|
217996_at |
0.831 |
5.076 |
3.526 |
3.002e-03 |
0.300 |
-1.532 |
PHLDA1 |
pleckstrin homology-like domain, family A, member 1 |
12 |
-74705493 |
AA576961 |
22822 |
12q15 |
Hs.602085 |
15 |
protein binding nucleus nucleolus cytoplasm apoptosis membrane cytoplasmic vesicle membrane cytoplasmic vesicle FasL biosynthetic process |
|
200999_s_at |
0.590 |
7.516 |
3.296 |
4.824e-03 |
0.339 |
-1.936 |
CKAP4 |
cytoskeleton-associated protein 4 |
12 |
-105155789 |
NM_006825 |
10970 |
12q23.3 |
Hs.714862 Hs.74368 |
22 |
membrane fraction endoplasmic reticulum membrane integral to membrane |
|
217403_s_at |
0.802 |
3.202 |
7.149 |
3.088e-06 |
0.039 |
4.013 |
ZNF227 |
zinc finger protein 227 |
19 |
49408530 |
AC074331 |
7770 |
|
Hs.371335 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
217761_at |
ADI1 |
acireductone dioxygenase 1 |
2 |
-3480696 |
NM_018269 |
55256 |
2p25.3 |
Hs.502773 |
13 |
protein binding nucleus cytoplasm plasma membrane cellular amino acid biosynthetic process methionine biosynthetic process nickel ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen methionine salvage metal ion binding oxidation reduction |
Cysteine and methionine metabolism Metabolic pathways |
225999_at |
0.523 |
5.149 |
2.943 |
9.950e-03 |
0.412 |
-2.552 |
RIMKLB |
ribosomal modification protein rimK-like family member B |
12 |
8741784 |
AI743612 |
57494 |
12p13.31 |
Hs.504670 |
4 |
nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding |
|
229799_s_at |
0.961 |
4.985 |
3.497 |
3.184e-03 |
0.305 |
-1.583 |
NCAM1 |
neural cell adhesion molecule 1 |
11 |
112337204, 112337204 |
AI569787 |
4684 |
11q23.1 |
Hs.503878 |
120 |
protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane |
Cell adhesion molecules (CAMs) Prion diseases |
218033_s_at |
0.716 |
5.345 |
2.958 |
9.647e-03 |
0.406 |
-2.526 |
SNN |
stannin |
16 |
11669801 |
NM_003498 |
8303 |
16p13 |
Hs.700592 |
11 |
response to stress response to abiotic stimulus membrane integral to membrane |
|
241389_at |
CHRNB2 |
cholinergic receptor, nicotinic, beta 2 (neuronal) |
1 |
152806880 |
BE261002 |
1141 |
1q21.3 |
Hs.2306 |
59 |
conditioned taste aversion response to hypoxia nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport calcium ion transport smooth muscle contraction signal transduction synaptic transmission, cholinergic visual perception sensory perception of sound memory locomotory behavior visual learning external side of plasma membrane acetylcholine receptor activity integral to membrane sensory perception of pain vestibulocochlear nerve development optic nerve morphogenesis lateral geniculate nucleus development central nervous system projection neuron axonogenesis cell junction positive regulation of B cell proliferation positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion behavioral response to nicotine social behavior regulation of dopamine metabolic process B cell activation response to cocaine regulation of circadian sleep/wake cycle, REM sleep regulation of circadian sleep/wake cycle, non-REM sleep synapse postsynaptic membrane response to ethanol negative regulation of action potential regulation of dendrite morphogenesis cognition membrane depolarization regulation of synaptogenesis synaptic transmission involved in micturition |
|
219887_at |
-0.266 |
4.457 |
-3.436 |
3.612e-03 |
0.314 |
-1.690 |
CCDC87 |
coiled-coil domain containing 87 |
11 |
-66114215 |
NM_018219 |
55231 |
11q13.2 |
Hs.121072 |
3 |
|
|
227534_at |
0.798 |
6.441 |
4.235 |
7.000e-04 |
0.211 |
-0.300 |
C9orf21 |
chromosome 9 open reading frame 21 |
9 |
-98443353 |
AI655189 |
195827 |
9q22.32 |
Hs.44640 |
4 |
|
|
204736_s_at |
0.517 |
4.947 |
4.446 |
4.561e-04 |
0.193 |
0.059 |
CSPG4 |
chondroitin sulfate proteoglycan 4 |
15 |
-73753717 |
NM_001897 |
1464 |
15q24.2 |
Hs.513044 |
34 |
angiogenesis signal transducer activity receptor signaling protein tyrosine phosphatase signaling protein activity protein binding plasma membrane integral to plasma membrane signal transduction multicellular organismal development receptor signaling protein tyrosine kinase signaling protein activity cell surface cell differentiation cell projection tissue remodeling |
|
243409_at |
-0.258 |
5.675 |
-2.919 |
1.045e-02 |
0.418 |
-2.593 |
FOXL1 |
forkhead box L1 |
16 |
85169615 |
AI005407 |
2300 |
16q24 |
Hs.533830 |
7 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development DNA bending activity sequence-specific DNA binding |
|
221935_s_at |
0.449 |
5.848 |
2.145 |
4.852e-02 |
0.590 |
-3.879 |
C3orf64 |
chromosome 3 open reading frame 64 |
3 |
-69107057 |
AK023140 |
285203 |
3p14.1 |
Hs.518059 |
2 |
extracellular region endoplasmic reticulum transferase activity, transferring glycosyl groups |
|
225525_at |
1.019 |
7.458 |
2.759 |
1.447e-02 |
0.447 |
-2.869 |
KIAA1671 |
KIAA1671 |
22 |
23753940 |
AB051458 |
85379 |
22q11.23 |
Hs.419171 |
4 |
|
|
220984_s_at |
0.540 |
5.658 |
5.123 |
1.196e-04 |
0.162 |
1.165 |
SLCO5A1 |
solute carrier organic anion transporter family, member 5A1 |
8 |
-70747123, -70747123, -70747123 |
NM_030958 |
81796 |
8q13.3 |
Hs.152460 Hs.443609 |
3 |
transporter activity transport membrane integral to membrane |
|
221815_at |
0.945 |
5.603 |
3.717 |
2.024e-03 |
0.273 |
-1.197 |
ABHD2 |
abhydrolase domain containing 2 |
15 |
87432384 |
BE671816 |
11057 |
15q26.1 |
Hs.122337 Hs.705984 |
10 |
molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration |
|
219543_at |
0.906 |
4.884 |
4.216 |
7.269e-04 |
0.211 |
-0.332 |
PBLD |
phenazine biosynthesis-like protein domain containing |
10 |
-69714843, -69712422 |
NM_022129 |
64081 |
10pter-q25.3 |
Hs.198158 |
7 |
cellular_component biological_process biosynthetic process isomerase activity |
|
232306_at |
-0.249 |
3.172 |
-2.922 |
1.040e-02 |
0.418 |
-2.590 |
CDH26 |
cadherin-like 26 |
20 |
57966876, 58004823 |
BG289314 |
60437 |
20q13.2-q13.33 |
Hs.54973 |
4 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane |
|
203038_at |
0.528 |
6.589 |
4.587 |
3.437e-04 |
0.179 |
0.295 |
PTPRK |
protein tyrosine phosphatase, receptor type, K |
6 |
-128331617, -128331617 |
NM_002844 |
5796 |
6q22.2-q22.3 |
Hs.155919 |
20 |
receptor activity transmembrane receptor protein tyrosine phosphatase activity plasma membrane integral to plasma membrane cell-cell junction adherens junction protein amino acid dephosphorylation cell adhesion signal transduction transforming growth factor beta receptor signaling pathway beta-catenin binding cell surface negative regulation of keratinocyte proliferation negative regulation of transcription hydrolase activity protein kinase binding negative regulation of cell migration leading edge membrane protein localization at cell surface cellular response to reactive oxygen species cellular response to UV gamma-catenin binding negative regulation of cell cycle focal adhesion formation |
|
1553954_at |
ALG14 |
asparagine-linked glycosylation 14 homolog (S. cerevisiae) |
1 |
-95220866 |
BU682208 |
199857 |
1p21.3 |
Hs.408927 |
5 |
endoplasmic reticulum membrane integral to membrane |
N-Glycan biosynthesis Metabolic pathways |
213248_at |
LOC730101 |
hypothetical LOC730101 |
6 |
52637157 |
AL577024 |
730101 |
6p12.2 |
Hs.7921 |
2 |
|
|
208456_s_at |
0.756 |
6.926 |
4.106 |
9.107e-04 |
0.220 |
-0.521 |
RRAS2 |
related RAS viral (r-ras) oncogene homolog 2 |
11 |
-14256041, -14256041 |
NM_012250 |
22800 |
11p15.2 |
Hs.502004 |
25 |
nucleotide binding GTPase activity protein binding GTP binding intracellular endoplasmic reticulum plasma membrane Ras protein signal transduction cellular process positive regulation of cell migration |
MAPK signaling pathway Tight junction Regulation of actin cytoskeleton |
221764_at |
C19orf22 |
chromosome 19 open reading frame 22 |
19 |
-847502 |
AL574186 |
91300 |
19p13.3 |
Hs.557655 |
2 |
nucleic acid binding nucleus |
|
226649_at |
PANK1 |
pantothenate kinase 1 |
10 |
-91332728, -91332728 |
AI373299 |
53354 |
10q23.31 |
Hs.715502 |
10 |
nucleotide binding pantothenate kinase activity pantothenate kinase activity ATP binding cytoplasm cytosol coenzyme A biosynthetic process transferase activity |
Pantothenate and CoA biosynthesis Metabolic pathways |
241459_at |
LIMCH1 |
LIM and calponin homology domains 1 |
4 |
41057560, 41309675 |
AI494113 |
22998 |
4p13 |
Hs.335163 |
10 |
actin binding zinc ion binding actomyosin structure organization metal ion binding |
|
202985_s_at |
0.407 |
6.914 |
3.555 |
2.825e-03 |
0.294 |
-1.481 |
BAG5 |
BCL2-associated athanogene 5 |
14 |
-103092641, -103092641, -103092641 |
NM_004873 |
9529 |
14q32.33 |
Hs.5443 |
10 |
protein binding protein folding apoptosis |
|
208814_at |
0.533 |
7.388 |
2.828 |
1.259e-02 |
0.429 |
-2.751 |
HSPA4 |
heat shock 70kDa protein 4 |
5 |
132415560 |
AA043348 |
3308 |
5q31.1-q31.2 |
Hs.90093 |
108 |
nucleotide binding ATP binding nucleus cytoplasm response to unfolded protein cellular chaperone-mediated protein complex assembly mitochondrial outer membrane translocase complex assembly |
Antigen processing and presentation |
226538_at |
0.594 |
7.174 |
3.204 |
5.835e-03 |
0.357 |
-2.098 |
MAN2A1 |
mannosidase, alpha, class 2A, member 1 |
5 |
109053054 |
AV700323 |
4124 |
5q21-q22 |
Hs.432822 |
29 |
Golgi membrane in utero embryonic development liver development alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing mitochondrion organization vacuole organization respiratory gaseous exchange metabolic process zinc ion binding membrane integral to membrane hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding lung alveolus development |
N-Glycan biosynthesis Metabolic pathways |
220907_at |
GPR110 |
G protein-coupled receptor 110 |
6 |
-47095580, -47075771 |
NM_025048 |
266977 |
6p12.3 |
Hs.256897 |
11 |
G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane |
|
224339_s_at |
0.924 |
6.257 |
3.903 |
1.378e-03 |
0.245 |
-0.871 |
ANGPTL1 |
angiopoietin-like 1 |
1 |
-177085292 |
AB056476 |
9068 |
1q25.2 |
Hs.591474 |
19 |
receptor binding extracellular region extracellular space signal transduction |
|
1569796_s_at |
ATRNL1 |
attractin-like 1 |
10 |
116843113 |
BC035157 |
26033 |
10q26 |
Hs.501127 |
3 |
binding sugar binding membrane integral to membrane |
|
225043_at |
0.702 |
7.196 |
3.676 |
2.201e-03 |
0.276 |
-1.269 |
SLC15A4 |
solute carrier family 15, member 4 |
12 |
-127843692 |
AW304786 |
121260 |
12q24.32-q24.33 |
Hs.507260 Hs.699387 |
6 |
transporter activity oligopeptide transport protein transport symporter activity membrane integral to membrane |
|
233480_at |
0.516 |
3.492 |
3.687 |
2.151e-03 |
0.276 |
-1.249 |
TMEM43 |
transmembrane protein 43 |
3 |
14141440 |
AK026869 |
79188 |
3p25.1 |
Hs.517817 |
18 |
nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane |
|
221840_at |
PTPRE |
protein tyrosine phosphatase, receptor type, E |
10 |
129595314, 129735802 |
AA775177 |
5791 |
10q26 |
Hs.127022 |
33 |
transmembrane receptor protein tyrosine phosphatase activity protein binding cytoplasm plasma membrane protein amino acid phosphorylation protein amino acid dephosphorylation integral to membrane hydrolase activity |
|
202370_s_at |
0.521 |
7.815 |
3.393 |
3.943e-03 |
0.321 |
-1.765 |
CBFB |
core-binding factor, beta subunit |
16 |
65620550 |
NM_001755 |
865 |
16q22.1 |
Hs.460988 |
39 |
osteoblast differentiation transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus lymphocyte differentiation myeloid cell differentiation positive regulation of transcription from RNA polymerase II promoter cell maturation definitive hemopoiesis |
|
204589_at |
0.670 |
7.466 |
3.512 |
3.086e-03 |
0.302 |
-1.556 |
NUAK1 |
NUAK family, SNF1-like kinase, 1 |
12 |
-104981254 |
NM_014840 |
9891 |
12q23.3 |
Hs.719171 |
13 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity |
|
218567_x_at |
0.483 |
6.024 |
3.464 |
3.407e-03 |
0.308 |
-1.640 |
DPP3 |
dipeptidyl-peptidase 3 |
11 |
66004455 |
NM_005700 |
10072 |
11q12-q13.1 |
Hs.502914 |
29 |
aminopeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity dipeptidyl-peptidase activity zinc ion binding metal ion binding |
|
226178_at |
0.452 |
5.352 |
2.727 |
1.544e-02 |
0.458 |
-2.924 |
SOCS4 |
suppressor of cytokine signaling 4 |
14 |
54563593 |
BF446961 |
122809 |
14q22.2-q22.3 |
Hs.708344 |
7 |
protein binding intracellular signaling cascade negative regulation of signal transduction modification-dependent protein catabolic process regulation of growth |
Jak-STAT signaling pathway Insulin signaling pathway Type II diabetes mellitus |
212678_at |
0.309 |
5.639 |
2.844 |
1.218e-02 |
0.426 |
-2.723 |
NF1 |
neurofibromin 1 |
17 |
26446120, 26446120 |
AW054826 |
4763 |
17q11.2 |
Hs.113577 |
204 |
osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction |
MAPK signaling pathway |
238606_at |
ZNF747 |
zinc finger protein 747 |
16 |
-30450279 |
AV698217 |
65988 |
16p11.2 |
Hs.592032 |
3 |
nucleic acid binding intracellular regulation of transcription, DNA-dependent |
|
227025_at |
PPHLN1 |
periphilin 1 |
12 |
41006213, 41006213, 41006213, 41006213 |
BG284497 |
51535 |
12q12 |
Hs.444157 |
13 |
nucleus cytoplasm keratinization |
|
212915_at |
-0.865 |
9.177 |
-3.238 |
5.430e-03 |
0.352 |
-2.037 |
PDZRN3 |
PDZ domain containing ring finger 3 |
3 |
-73514341 |
AL569804 |
23024 |
3p13 |
Hs.719126 |
9 |
protein binding zinc ion binding metal ion binding |
|
228525_at |
LRP3 |
low density lipoprotein receptor-related protein 3 |
19 |
38377438 |
AL583533 |
4037 |
19q13.11 |
Hs.515340 Hs.715569 |
9 |
receptor activity coated pit receptor-mediated endocytosis membrane integral to membrane |
|
214455_at |
1.058 |
3.861 |
2.867 |
1.163e-02 |
0.426 |
-2.684 |
HIST1H2BC |
histone cluster 1, H2bc |
6 |
-26231673 |
NM_003526 |
8347 |
6p21.3 |
Hs.658713 |
10 |
nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly defense response to bacterium |
Systemic lupus erythematosus |
222547_at |
0.588 |
5.098 |
3.521 |
3.029e-03 |
0.300 |
-1.540 |
MAP4K4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
2 |
101680919 |
AL561281 |
9448 |
2q11.2-q12 |
Hs.719073 |
22 |
nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade transferase activity |
MAPK signaling pathway |
1565254_s_at |
0.314 |
4.196 |
3.868 |
1.483e-03 |
0.250 |
-0.933 |
ELL |
elongation factor RNA polymerase II |
19 |
-18414473 |
AF272374 |
8178 |
19p13.1 |
Hs.515260 |
26 |
protein binding nucleus nucleoplasm RNA elongation from RNA polymerase II promoter transcription elongation factor complex positive transcription elongation factor activity Cajal body nuclear speck RNA polymerase II transcription elongation factor activity regulation of transcription |
|
225972_at |
0.864 |
6.355 |
3.326 |
4.534e-03 |
0.332 |
-1.883 |
TMEM64 |
transmembrane protein 64 |
8 |
-91703398 |
AA524005 |
169200 |
8q21.3 |
Hs.567759 |
2 |
membrane integral to membrane |
|
225886_at |
0.523 |
6.944 |
4.456 |
4.476e-04 |
0.193 |
0.075 |
DDX5 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 |
17 |
-59924835 |
AA156797 |
1655 |
17q21 |
Hs.279806 |
50 |
nucleotide binding RNA binding RNA helicase activity protein binding ATP binding nucleus spliceosomal complex nucleolus mRNA processing ATP-dependent helicase activity RNA splicing cell growth hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
|
239093_at |
0.566 |
4.587 |
3.312 |
4.665e-03 |
0.336 |
-1.908 |
DHDPSL |
dihydrodipicolinate synthase-like, mitochondrial |
10 |
99334091 |
BG165743 |
112817 |
10q24.2 |
Hs.180346 |
4 |
mitochondrion metabolic process lyase activity |
|
205842_s_at |
0.784 |
5.011 |
3.166 |
6.305e-03 |
0.363 |
-2.164 |
JAK2 |
Janus kinase 2 |
9 |
4975244 |
AF001362 |
3717 |
9p24 |
Hs.656213 |
588 |
nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding ATP binding nucleus cytoplasm cytoskeleton caveola apoptosis cell motion enzyme linked receptor protein signaling pathway tyrosine phosphorylation of STAT protein STAT protein nuclear translocation mesoderm development negative regulation of cell proliferation positive regulation of phosphoinositide 3-kinase cascade membrane transferase activity myeloid cell differentiation SH2 domain binding positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of DNA binding response to antibiotic positive regulation of peptidyl-tyrosine phosphorylation JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway |
Chemokine signaling pathway Jak-STAT signaling pathway Adipocytokine signaling pathway |
219225_at |
0.644 |
5.549 |
5.302 |
8.459e-05 |
0.162 |
1.447 |
PGBD5 |
piggyBac transposable element derived 5 |
1 |
-228524014 |
NM_024554 |
79605 |
1q42.13 |
Hs.520463 |
3 |
membrane integral to membrane |
|
226632_at |
CYGB |
cytoglobin |
17 |
-72035034 |
AL513673 |
114757 |
17q25.3 |
Hs.95120 |
28 |
peroxidase activity oxygen transporter activity cytoplasm transport response to oxidative stress oxygen transport oxygen binding heme binding neuron projection cell soma metal ion binding |
|
229840_at |
-0.342 |
5.819 |
-3.644 |
2.349e-03 |
0.284 |
-1.324 |
IQSEC2 |
IQ motif and Sec7 domain 2 |
X |
-53312230, -53278789, -53278782 |
AW026036 |
23096 |
Xp11.22 |
Hs.496138 |
10 |
ARF guanyl-nucleotide exchange factor activity intracellular cytoplasm regulation of ARF protein signal transduction |
Endocytosis |
229310_at |
0.802 |
5.992 |
2.792 |
1.354e-02 |
0.438 |
-2.813 |
KLHL29 |
kelch-like 29 (Drosophila) |
2 |
|
BE465475 |
114818 |
2p24.1 |
Hs.130593 |
5 |
protein binding |
|
209804_at |
0.695 |
5.084 |
3.081 |
7.501e-03 |
0.376 |
-2.312 |
DCLRE1A |
DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae) |
10 |
-115584473 |
D42045 |
9937 |
10q25.1 |
Hs.1560 |
14 |
nucleus nucleotide-excision repair response to DNA damage stimulus cell cycle mitosis cell division |
|
218521_s_at |
0.744 |
6.304 |
2.779 |
1.391e-02 |
0.442 |
-2.836 |
UBE2W |
ubiquitin-conjugating enzyme E2W (putative) |
8 |
-74865393 |
NM_018299 |
55284 |
8q21.11 |
Hs.597486 |
7 |
nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
209825_s_at |
0.644 |
6.658 |
3.902 |
1.382e-03 |
0.245 |
-0.874 |
UCK2 |
uridine-cytidine kinase 2 |
1 |
164063513 |
BC002906 |
7371 |
1q23 |
Hs.458360 |
22 |
nucleotide binding molecular_function uridine kinase activity ATP binding cellular_component cytosol metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor |
Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways |
213034_at |
QSK |
serine/threonine-protein kinase QSK |
11 |
-116219327 |
AB023216 |
23387 |
11q23.3 |
Hs.167451 |
14 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
212442_s_at |
LASS6 |
LAG1 homolog, ceramide synthase 6 |
2 |
169021080 |
BG289001 |
253782 |
2q24.3 |
Hs.506829 Hs.718403 |
5 |
transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding ceramide biosynthetic process sphingosine N-acyltransferase activity |
|
1554801_at |
-0.380 |
3.306 |
-3.834 |
1.590e-03 |
0.258 |
-0.992 |
C5orf40 |
chromosome 5 open reading frame 40 |
5 |
-156701184 |
BC022570 |
408263 |
5q33.3 |
Hs.437066 |
3 |
membrane integral to membrane |
|
222942_s_at |
1.031 |
5.655 |
4.188 |
7.700e-04 |
0.211 |
-0.380 |
TIAM2 |
T-cell lymphoma invasion and metastasis 2 |
6 |
155453114, 155579788 |
AI094945 |
26230 |
6q25.2 |
Hs.586279 |
5 |
receptor signaling protein activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm intracellular signaling cascade lamellipodium filopodium growth cone regulation of Rho protein signal transduction |
Chemokine signaling pathway Regulation of actin cytoskeleton |
222731_at |
ZDHHC2 |
zinc finger, DHHC-type containing 2 |
8 |
17058206 |
AK001608 |
51201 |
8p21.3-p22 |
Hs.443852 |
8 |
zinc ion binding membrane integral to membrane palmitoyltransferase activity transferase activity protein palmitoylation metal ion binding |
|
215071_s_at |
0.780 |
7.430 |
3.873 |
1.466e-03 |
0.250 |
-0.924 |
HIST1H2AC |
histone cluster 1, H2ac |
6 |
26232351 |
AL353759 |
8334 |
6p21.3 |
Hs.699831 |
19 |
nucleosome DNA binding nucleus chromosome nucleosome assembly |
Systemic lupus erythematosus |
226184_at |
FMNL2 |
formin-like 2 |
2 |
152899996 |
AI123567 |
114793 |
2q23.3 |
Hs.654630 |
9 |
actin binding cytoplasm cellular component organization Rho GTPase binding actin cytoskeleton organization |
|
205173_x_at |
0.329 |
6.740 |
2.331 |
3.388e-02 |
0.552 |
-3.583 |
CD58 |
CD58 molecule |
1 |
-116862845, -116858679 |
NM_001779 |
965 |
1p13 |
Hs.34341 |
38 |
protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane |
Cell adhesion molecules (CAMs) |
221495_s_at |
0.324 |
7.674 |
2.898 |
1.091e-02 |
0.423 |
-2.630 |
TCF25 |
transcription factor 25 (basic helix-loop-helix) |
16 |
88467494 |
AF322111 |
22980 |
16q24.3 |
Hs.415342 |
9 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus heart development regulation of transcription |
|
232604_at |
0.588 |
5.571 |
4.601 |
3.342e-04 |
0.179 |
0.318 |
ZNF541 |
zinc finger protein 541 |
19 |
-52715759 |
AL136846 |
84215 |
19q13.33 |
Hs.14161 |
3 |
DNA binding intracellular nucleus multicellular organismal development spermatogenesis zinc ion binding cell differentiation regulation of transcription metal ion binding |
|
215675_at |
-0.307 |
5.001 |
-2.697 |
1.642e-02 |
0.464 |
-2.976 |
TEF |
thyrotrophic embryonic factor |
22 |
40093337, 40107908 |
AB051442 |
7008 |
22q13 22q13.2 |
Hs.181159 |
14 |
transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity rhythmic process |
|
215804_at |
-0.464 |
4.861 |
-4.359 |
5.440e-04 |
0.207 |
-0.088 |
EPHA1 |
EPH receptor A1 |
7 |
-142798327 |
Z27409 |
2041 |
7q34 |
Hs.89839 |
30 |
nucleotide binding receptor activity ephrin receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity |
Axon guidance |
223886_s_at |
RNF146 |
ring finger protein 146 |
6 |
127629712 |
AL136829 |
81847 |
6q22.1-q22.33 |
Hs.267120 |
12 |
protein binding zinc ion binding metal ion binding |
|
201594_s_at |
0.324 |
7.518 |
3.446 |
3.541e-03 |
0.311 |
-1.673 |
PPP4R1 |
protein phosphatase 4, regulatory subunit 1 |
18 |
-9536791 |
NM_005134 |
9989 |
18p11.22 |
Hs.719096 |
11 |
protein binding soluble fraction signal transduction protein phosphatase type 4 regulator activity |
|
228793_at |
JMJD1C |
jumonji domain containing 1C |
10 |
-64596993, -64596993 |
BF002296 |
221037 |
10q21.3 |
Hs.413416 |
10 |
iron ion binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding thyroid hormone receptor binding oxidation reduction |
|
216048_s_at |
0.577 |
4.799 |
4.122 |
8.805e-04 |
0.219 |
-0.493 |
RHOBTB3 |
Rho-related BTB domain containing 3 |
5 |
95092605 |
AK023621 |
22836 |
5q15 |
Hs.445030 |
13 |
protein binding ATP binding ATPase activity Rab GTPase binding retrograde transport, endosome to Golgi |
|
228279_s_at |
TNK2 |
tyrosine kinase, non-receptor, 2 |
3 |
-197074632, -197074632 |
BE676245 |
10188 |
3q29 |
Hs.518513 |
37 |
nucleotide binding magnesium ion binding non-membrane spanning protein tyrosine kinase activity GTPase inhibitor activity protein binding ATP binding plasma membrane protein amino acid phosphorylation small GTPase mediated signal transduction transferase activity positive regulation of peptidyl-tyrosine phosphorylation |
|
242157_at |
1.049 |
4.464 |
5.068 |
1.330e-04 |
0.169 |
1.078 |
CHD9 |
chromodomain helicase DNA binding protein 9 |
16 |
51646445 |
AW469037 |
80205 |
16q12.2 |
Hs.59159 Hs.622347 |
10 |
nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription |
|
201544_x_at |
0.505 |
9.087 |
4.804 |
2.235e-04 |
0.172 |
0.652 |
PABPN1 |
poly(A) binding protein, nuclear 1 |
14 |
22859236 |
BF675004 |
8106 |
14q11.2-q13 |
Hs.707712 |
42 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm muscle contraction poly(A)+ mRNA export from nucleus |
|
212582_at |
0.913 |
7.202 |
3.799 |
1.707e-03 |
0.267 |
-1.053 |
OSBPL8 |
oxysterol binding protein-like 8 |
12 |
-75269708 |
AL049923 |
114882 |
12q14 |
Hs.430849 |
13 |
lipid transport steroid metabolic process |
|
224743_at |
0.620 |
8.892 |
3.344 |
4.364e-03 |
0.328 |
-1.851 |
IMPAD1 |
inositol monophosphatase domain containing 1 |
8 |
-58033041 |
BF674724 |
54928 |
8q12.1 |
Hs.716471 |
4 |
magnesium ion binding inositol-1(or 4)-monophosphatase activity membrane integral to membrane hydrolase activity |
|
201155_s_at |
-0.309 |
9.746 |
-2.644 |
1.825e-02 |
0.480 |
-3.065 |
MFN2 |
mitofusin 2 |
1 |
11962824 |
NM_014874 |
9927 |
1p36.22 |
Hs.376681 |
43 |
nucleotide binding blastocyst formation GTPase activity protein binding GTP binding mitochondrion cytosol protein targeting to mitochondrion mitochondrial membrane organization cell cycle arrest mitochondrial fusion microtubule cytoskeleton membrane integral to membrane hydrolase activity intrinsic to mitochondrial outer membrane negative regulation of Ras protein signal transduction camera-type eye morphogenesis negative regulation of smooth muscle cell proliferation mitochondrion localization |
|
219630_at |
0.304 |
4.213 |
3.172 |
6.230e-03 |
0.362 |
-2.154 |
PDZK1IP1 |
PDZK1 interacting protein 1 |
1 |
-47421847 |
NM_005764 |
10158 |
1p33 |
Hs.431099 |
16 |
membrane integral to membrane |
|
217759_at |
0.349 |
6.964 |
4.073 |
9.739e-04 |
0.223 |
-0.578 |
TRIM44 |
tripartite motif-containing 44 |
11 |
35640928 |
BF431488 |
54765 |
11p13 |
Hs.192103 |
10 |
intracellular zinc ion binding metal ion binding |
|
214657_s_at |
0.856 |
5.063 |
4.504 |
4.062e-04 |
0.192 |
0.156 |
NEAT1 |
nuclear paraspeckle assembly transcript 1 (non-protein coding) |
11 |
64946844, 64946844 |
AU134977 |
283131 |
11q13.1 |
Hs.523789 Hs.648467 |
6 |
|
|
216251_s_at |
0.424 |
6.200 |
4.519 |
3.939e-04 |
0.192 |
0.181 |
TTLL12 |
tubulin tyrosine ligase-like family, member 12 |
22 |
-41892571 |
BF965437 |
23170 |
22q13.31 |
Hs.517670 |
6 |
tubulin-tyrosine ligase activity protein modification process |
|
225962_at |
ZNRF1 |
zinc and ring finger 1 |
16 |
73590415 |
AI199541 |
84937 |
16q23.1 |
Hs.427284 |
11 |
protein binding lysosome endosome zinc ion binding membrane ligase activity modification-dependent protein catabolic process cell junction cytoplasmic vesicle synapse metal ion binding |
|
1555379_at |
FAM159A |
family with sequence similarity 159, member A |
1 |
52871653 |
BC041608 |
348378 |
1p32.3 |
Hs.424589 |
2 |
membrane integral to membrane |
|
36554_at |
0.540 |
5.830 |
3.235 |
5.467e-03 |
0.352 |
-2.043 |
ASMTL |
acetylserotonin O-methyltransferase-like |
X, Y |
-1482031, -1482031 |
Y15521 |
8623 |
Xp22.3 Yp11.3 |
Hs.533514 |
10 |
cellular_component cytoplasm acetylserotonin O-methyltransferase activity melatonin biosynthetic process |
|
239297_at |
C8orf79 |
chromosome 8 open reading frame 79 |
8 |
12847553, 12914143 |
BE932011 |
57604 |
8p22 |
Hs.202521 |
5 |
metabolic process methyltransferase activity transferase activity |
|
1560382_at |
-0.369 |
5.326 |
-4.360 |
5.430e-04 |
0.207 |
-0.087 |
GAB1 |
GRB2-associated binding protein 1 |
4 |
144477432 |
AK074381 |
2549 |
4q31.21 |
Hs.618456 Hs.80720 |
69 |
SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway |
ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma |
221733_s_at |
-0.356 |
4.038 |
-3.765 |
1.831e-03 |
0.270 |
-1.112 |
GPATCH4 |
G patch domain containing 4 |
1 |
-154830902 |
BE546897 |
54865 |
1q22 |
Hs.193832 Hs.708599 |
3 |
nucleic acid binding intracellular |
|
212666_at |
0.398 |
5.449 |
2.696 |
1.644e-02 |
0.464 |
-2.977 |
SMURF1 |
SMAD specific E3 ubiquitin protein ligase 1 |
7 |
-98462999 |
AB046845 |
57154 |
7q22.1 |
Hs.189329 |
34 |
ubiquitin-protein ligase activity protein binding intracellular cytoplasm plasma membrane protein modification process protein export from nucleus ectoderm development ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation negative regulation of ossification negative regulation of BMP signaling pathway ubiquitin-dependent SMAD protein catabolic process positive regulation of protein ubiquitination receptor catabolic process protein localization at cell surface protein ubiquitination during ubiquitin-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process activin binding I-SMAD binding R-SMAD binding |
Ubiquitin mediated proteolysis Endocytosis TGF-beta signaling pathway |
212610_at |
0.355 |
10.103 |
2.216 |
4.234e-02 |
0.575 |
-3.767 |
PTPN11 |
protein tyrosine phosphatase, non-receptor type 11 |
12 |
111340918 |
U79291 |
5781 |
12q24 |
Hs.506852 Hs.646231 |
326 |
non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity |
Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia |
218750_at |
0.610 |
5.525 |
3.536 |
2.940e-03 |
0.298 |
-1.515 |
TAF1D |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
11 |
-93108745 |
NM_024116 |
79101 |
11q21 |
Hs.355750 |
6 |
DNA binding protein binding nucleus regulation of transcription |
|
212461_at |
0.339 |
8.606 |
2.725 |
1.552e-02 |
0.458 |
-2.928 |
AZIN1 |
antizyme inhibitor 1 |
8 |
-103907711 |
BF793951 |
51582 |
8q22.3 |
Hs.459106 |
10 |
catalytic activity protein binding polyamine biosynthetic process ornithine decarboxylase inhibitor activity ornithine decarboxylase activator activity |
|
223805_at |
0.512 |
8.468 |
2.860 |
1.180e-02 |
0.426 |
-2.696 |
OSBPL6 |
oxysterol binding protein-like 6 |
2 |
178767619, 178893216 |
AF323728 |
114880 |
2q31-q32.1 |
Hs.318775 |
7 |
lipid transport steroid metabolic process |
|
1556190_s_at |
0.538 |
3.310 |
4.320 |
5.887e-04 |
0.211 |
-0.154 |
PRNP |
prion protein |
20 |
4614796, 4615156 |
AK056897 |
5621 |
20p13 |
Hs.472010 Hs.610285 Hs.707152 Hs.714553 |
353 |
copper ion binding cytoplasm endoplasmic reticulum Golgi apparatus plasma membrane cellular copper ion homeostasis anti-apoptosis response to oxidative stress microtubule binding metabolic process extrinsic to membrane anchored to membrane identical protein binding membrane raft response to cadmium ion response to copper ion protein homooligomerization |
Prion diseases |
203183_s_at |
-0.243 |
4.668 |
-2.799 |
1.335e-02 |
0.435 |
-2.801 |
SMARCD1 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
12 |
48765249 |
NM_003076 |
6602 |
12q13-q14 |
Hs.79335 |
23 |
transcription coactivator activity nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase II promoter SWI/SNF complex chromatin remodeling complex protein complex scaffold chromatin-mediated maintenance of transcription |
|
223681_s_at |
INADL |
InaD-like (Drosophila) |
1 |
61980736 |
AB044807 |
10207 |
1p31.3 |
Hs.478125 |
24 |
protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction |
Tight junction |
1566147_a_at |
-0.351 |
5.322 |
-2.880 |
1.133e-02 |
0.426 |
-2.662 |
LOC375010 |
ankyrin repeat domain 20 family, member A pseudogene |
1 |
|
AK098337 |
375010 |
1q21.1 |
Hs.672092 |
1 |
|
|
220241_at |
0.488 |
3.100 |
2.950 |
9.809e-03 |
0.409 |
-2.540 |
TMCO3 |
transmembrane and coiled-coil domains 3 |
13 |
113193308 |
NM_017905 |
55002 |
13q34 |
Hs.317593 |
6 |
cation transport antiporter activity solute:hydrogen antiporter activity membrane integral to membrane |
|
238727_at |
0.762 |
3.259 |
3.972 |
1.197e-03 |
0.234 |
-0.752 |
LOC440934 |
hypothetical LOC440934 |
2 |
|
AA031832 |
440934 |
2q36.1 |
Hs.715764 |
1 |
|
|
208385_at |
-0.252 |
4.801 |
-2.210 |
4.285e-02 |
0.576 |
-3.777 |
NR2E3 |
nuclear receptor subfamily 2, group E, member 3 |
15 |
69889947, 69889947 |
NM_016346 |
10002 |
15q22.32 |
Hs.187354 |
23 |
transcription factor activity steroid hormone receptor activity steroid binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter signal transduction visual perception phototransduction zinc ion binding sequence-specific DNA binding metal ion binding response to stimulus |
|
233918_at |
DCDC2B |
doublecortin domain containing 2B |
1 |
32447281 |
AI924786 |
149069 |
1p35.1 |
Hs.424588 |
1 |
intracellular signaling cascade |
|
203699_s_at |
0.604 |
3.922 |
4.268 |
6.547e-04 |
0.211 |
-0.244 |
DIO2 |
deiodinase, iodothyronine, type II |
14 |
-79733621, -79733621 |
U53506 |
1734 |
14q24.2-q24.3 |
Hs.202354 |
61 |
selenocysteine incorporation thyroxine 5'-deiodinase activity thyroid hormone generation selenium binding membrane integral to membrane thyroid hormone catabolic process hormone biosynthetic process oxidation reduction |
|
211548_s_at |
0.754 |
5.023 |
4.207 |
7.410e-04 |
0.211 |
-0.348 |
HPGD |
hydroxyprostaglandin dehydrogenase 15-(NAD) |
4 |
-175647902, -175647902 |
J05594 |
3248 |
4q34-q35 |
Hs.596913 |
47 |
prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction |
|
1563511_at |
0.600 |
5.231 |
3.237 |
5.445e-03 |
0.352 |
-2.039 |
DKFZp451B082 |
hypothetical gene supported by AL831931 |
6 |
|
AL831931 |
401282 |
6q26 |
Hs.444817 |
|
|
|
221825_at |
0.448 |
7.512 |
2.651 |
1.801e-02 |
0.476 |
-3.054 |
ANGEL2 |
angel homolog 2 (Drosophila) |
1 |
-211232146 |
AU151793 |
90806 |
1q32.3 |
Hs.157078 |
3 |
|
|
224276_at |
0.641 |
3.695 |
4.941 |
1.707e-04 |
0.171 |
0.874 |
ZNF33A |
zinc finger protein 33A |
10 |
38339583 |
AF063599 |
7581 |
10p11.2 |
Hs.435774 |
8 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
214152_at |
0.427 |
7.299 |
3.073 |
7.628e-03 |
0.378 |
-2.326 |
CCPG1 |
cell cycle progression 1 |
15 |
-53434729, -53434729 |
AU144243 |
9236 |
15q21.1 |
Hs.285051 |
5 |
cell cycle membrane integral to membrane |
|
238877_at |
EYA4 |
eyes absent homolog 4 (Drosophila) |
6 |
133604187 |
BE674583 |
2070 |
6q23 |
Hs.596680 |
15 |
magnesium ion binding protein tyrosine phosphatase activity nucleus cytoplasm DNA repair response to DNA damage stimulus multicellular organismal development visual perception metabolic process anatomical structure morphogenesis chromatin modification hydrolase activity regulation of transcription |
|
209721_s_at |
0.415 |
7.258 |
2.670 |
1.732e-02 |
0.471 |
-3.021 |
IFFO1 |
intermediate filament family orphan 1 |
12 |
-6518954, -6518954 |
BC002857 |
25900 |
12p13.3 |
Hs.15243 |
7 |
intermediate filament |
|
211862_x_at |
0.697 |
7.214 |
4.188 |
7.690e-04 |
0.211 |
-0.379 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AF015451 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
236193_at |
0.834 |
5.263 |
3.024 |
8.430e-03 |
0.388 |
-2.411 |
HIST1H2BC |
histone cluster 1, H2bc |
6 |
-26231673 |
AA037483 |
8347 |
6p21.3 |
Hs.658713 |
10 |
nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly defense response to bacterium |
Systemic lupus erythematosus |
203066_at |
1.346 |
6.357 |
3.724 |
1.994e-03 |
0.273 |
-1.184 |
CHST15 |
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
10 |
-125757173 |
NM_014863 |
51363 |
10q26 |
Hs.287537 |
12 |
Golgi apparatus membrane integral to membrane transferase activity hexose biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate binding N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity |
Chondroitin sulfate biosynthesis |
1560097_at |
-0.384 |
4.776 |
-3.416 |
3.762e-03 |
0.317 |
-1.725 |
FHAD1 |
forkhead-associated (FHA) phosphopeptide binding domain 1 |
1 |
15446354 |
AB067524 |
114827 |
1p36.21 |
Hs.659997 |
6 |
|
|
205149_s_at |
0.666 |
5.396 |
3.541 |
2.908e-03 |
0.298 |
-1.506 |
CLCN4 |
chloride channel 4 |
X |
10084984 |
NM_001830 |
1183 |
Xp22.3 |
Hs.495674 |
17 |
nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding |
|
234876_at |
COX6A1 |
cytochrome c oxidase subunit VIa polypeptide 1 |
12 |
119360286 |
U82486 |
1337 |
12q24.2 |
Hs.497118 |
11 |
cytochrome-c oxidase activity mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex IV generation of precursor metabolites and energy membrane |
Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease |
209211_at |
1.304 |
4.661 |
3.158 |
6.408e-03 |
0.364 |
-2.178 |
KLF5 |
Kruppel-like factor 5 (intestinal) |
13 |
72531142 |
AF132818 |
688 |
13q22.1 |
Hs.508234 |
50 |
angiogenesis transcription factor activity RNA polymerase II transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter zinc ion binding positive regulation of cell proliferation microvillus assembly positive regulation of transcription metal ion binding |
|
203883_s_at |
0.333 |
7.209 |
3.478 |
3.310e-03 |
0.308 |
-1.615 |
RAB11FIP2 |
RAB11 family interacting protein 2 (class I) |
10 |
-119754418 |
BG249608 |
22841 |
10q26.11 |
Hs.173656 |
20 |
protein binding endosome plasma membrane protein transport |
Endocytosis |
202263_at |
0.440 |
11.457 |
3.012 |
8.645e-03 |
0.392 |
-2.432 |
CYB5R1 |
cytochrome b5 reductase 1 |
1 |
-201197624 |
NM_016243 |
51706 |
1p36.13-q41 |
Hs.334832 |
8 |
cytochrome-b5 reductase activity electron carrier activity membrane integral to membrane sterol biosynthetic process oxidoreductase activity oxidation reduction |
Amino sugar and nucleotide sugar metabolism |
209025_s_at |
0.429 |
7.549 |
2.472 |
2.572e-02 |
0.517 |
-3.353 |
SYNCRIP |
synaptotagmin binding, cytoplasmic RNA interacting protein |
6 |
-86380411, -86380411, -86374221, -86374221, -86374221, -86374221 |
AF037448 |
10492 |
6q14-q15 |
Hs.571177 |
33 |
nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms |
|
237833_s_at |
-0.252 |
5.311 |
-2.396 |
2.987e-02 |
0.537 |
-3.478 |
SNCAIP |
synuclein, alpha interacting protein |
5 |
121675718 |
BF062366 |
9627 |
5q23.1-q23.3 |
Hs.426463 |
40 |
protein binding cytoplasm dopamine metabolic process presynaptic membrane cell soma regulation of neurotransmitter secretion |
Parkinson's disease |
232252_at |
0.510 |
9.385 |
3.593 |
2.611e-03 |
0.287 |
-1.414 |
DUSP27 |
dual specificity phosphatase 27 (putative) |
1 |
165330710 |
AI822125 |
92235 |
1q22-q24 |
Hs.632462 |
2 |
protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity phosphatase activity |
|
201647_s_at |
SCARB2 |
scavenger receptor class B, member 2 |
4 |
-77298917 |
NM_005506 |
950 |
4q21.1 |
Hs.349656 Hs.714206 |
24 |
receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane |
Lysosome |
211476_at |
0.948 |
8.067 |
2.167 |
4.654e-02 |
0.582 |
-3.845 |
MYOZ2 |
myozenin 2 |
4 |
120276386 |
AY013295 |
51778 |
4q26-q27 |
Hs.381047 |
16 |
protein binding cytoplasm biological_process actin cytoskeleton sarcomere Z disc protein phosphatase 2B binding |
|
213174_at |
0.343 |
6.200 |
2.445 |
2.710e-02 |
0.525 |
-3.397 |
TTC9 |
tetratricopeptide repeat domain 9 |
14 |
70178256 |
BE675549 |
23508 |
14q24.2 |
Hs.79170 |
5 |
binding protein folding |
|
206538_at |
0.423 |
6.518 |
2.611 |
1.950e-02 |
0.490 |
-3.121 |
MRAS |
muscle RAS oncogene homolog |
3 |
139549314, 139550197 |
NM_012219 |
22808 |
3q22.3 |
Hs.527021 |
18 |
nucleotide binding GTPase activity GTP binding intracellular plasma membrane Ras protein signal transduction multicellular organismal development muscle organ development actin cytoskeleton organization GTP-dependent protein binding |
MAPK signaling pathway Tight junction Regulation of actin cytoskeleton |
226561_at |
AGFG1 |
ArfGAP with FG repeats 1 |
2 |
228045131 |
BE551849 |
3267 |
2q36.3 |
Hs.352962 |
29 |
DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding |
|
233516_s_at |
SPAG17 |
sperm associated antigen 17 |
1 |
-118297810 |
AL137581 |
200162 |
1p12 |
Hs.528821 |
7 |
protein binding cytoplasm microtubule cilium flagellum flagellar axoneme |
|
217596_at |
0.267 |
5.341 |
2.760 |
1.444e-02 |
0.447 |
-2.867 |
UPF3A |
UPF3 regulator of nonsense transcripts homolog A (yeast) |
13 |
114065179 |
AA649851 |
65110 |
13q34 |
Hs.533855 |
20 |
nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay RNA binding nucleocytoplasmic transporter activity protein binding nucleus cytoplasm transport mRNA transport |
|
233557_s_at |
0.247 |
5.174 |
2.638 |
1.845e-02 |
0.484 |
-3.074 |
MON1B |
MON1 homolog B (yeast) |
16 |
75782336 |
AK023374 |
22879 |
16q23.1 |
Hs.513743 |
6 |
|
|
204281_at |
TEAD4 |
TEA domain family member 4 |
12 |
2938756, 2939222 |
NM_003213 |
7004 |
12p13.3-p13.2 |
Hs.94865 |
16 |
skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter muscle organ development |
|
238124_at |
0.727 |
8.554 |
3.076 |
7.586e-03 |
0.378 |
-2.321 |
MYOM3 |
myomesin family, member 3 |
1 |
-24255117 |
AI124053 |
127294 |
1p36.11 |
Hs.523413 |
4 |
|
|
222976_s_at |
0.755 |
8.823 |
3.415 |
3.774e-03 |
0.318 |
-1.727 |
TPM3 |
tropomyosin 3 |
1 |
-152400913, -152394403 |
BC000771 |
7170 |
1q21.2 |
Hs.535581 Hs.644306 Hs.654421 |
66 |
molecular_function actin binding protein binding cytoplasm cytoskeleton cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction |
Cardiac muscle contraction Pathways in cancer Thyroid cancer Hypertrophic cardiomyopathy (HCM) |
229144_at |
0.243 |
5.074 |
2.859 |
1.182e-02 |
0.426 |
-2.698 |
RP1-21O18.1 |
kazrin |
1 |
14797799, 14797799, 15123211, 15128882, 15145001 |
AA989362 |
23254 |
1p36.21 |
Hs.368823 |
10 |
nucleus cytoplasm cytoskeleton cell junction desmosome keratinization |
|
224726_at |
0.268 |
7.604 |
2.338 |
3.343e-02 |
0.552 |
-3.572 |
MIB1 |
mindbomb homolog 1 (Drosophila) |
18 |
17575542 |
W80418 |
57534 |
18q11.2 |
Hs.140903 Hs.658808 |
15 |
blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding |
|
221755_at |
0.310 |
7.999 |
2.340 |
3.331e-02 |
0.552 |
-3.569 |
EHBP1L1 |
EH domain binding protein 1-like 1 |
11 |
65100084 |
BG334196 |
254102 |
11q13.1 |
Hs.502867 |
4 |
|
|
209674_at |
0.565 |
6.958 |
2.725 |
1.549e-02 |
0.458 |
-2.927 |
CRY1 |
cryptochrome 1 (photolyase-like) |
12 |
-105909271 |
D83702 |
1407 |
12q23-q24.1 |
Hs.151573 |
23 |
nucleotide binding DNA binding DNA photolyase activity nucleus cytoplasm mitochondrion DNA repair circadian rhythm G-protein coupled photoreceptor activity protein-chromophore linkage regulation of transcription response to stimulus |
Circadian rhythm - mammal |
219757_s_at |
0.354 |
4.706 |
2.339 |
3.338e-02 |
0.552 |
-3.570 |
C14orf101 |
chromosome 14 open reading frame 101 |
14 |
56116263 |
NM_017799 |
54916 |
14q22.3 |
Hs.497253 |
3 |
membrane integral to membrane |
|
203156_at |
AKAP11 |
A kinase (PRKA) anchor protein 11 |
13 |
41744288 |
NM_016248 |
11215 |
13q14.11 |
Hs.105105 |
14 |
cytoplasm centrosome protein kinase cascade protein phosphatase 1 binding protein kinase A binding |
|
225859_at |
XIAP |
X-linked inhibitor of apoptosis |
X |
122821728 |
N30645 |
331 |
Xq25 |
Hs.356076 |
170 |
protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding |
Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer |
200816_s_at |
PAFAH1B1 |
platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa) |
17 |
2443672 |
NM_000430 |
5048 |
17p13.3 |
Hs.77318 |
75 |
establishment of mitotic spindle orientation astral microtubule kinetochore acrosome assembly neuron migration nucleus cytoplasm centrosome spindle cytosol microtubule microtubule associated complex cell cortex transport cell cycle mitosis synaptic transmission multicellular organismal development nervous system development neuroblast proliferation learning or memory microtubule binding retrograde axon cargo transport heparin binding adult locomotory behavior membrane lipid catabolic process corpus callosum morphogenesis hippocampus development layer formation in the cerebral cortex cerebral cortex development actin cytoskeleton organization cell differentiation microtubule organizing center organization cell leading edge motile primary cilium nonmotile primary cilium nuclear membrane regulation of Rho GTPase activity dynactin binding protein homodimerization activity phospholipase binding dynein binding platelet activating factor metabolic process vesicle transport along microtubule perinuclear region of cytoplasm brain morphogenesis neuromuscular process controlling balance phosphoprotein binding cell division |
Ether lipid metabolism Metabolic pathways |
228067_at |
-0.484 |
5.292 |
-2.713 |
1.587e-02 |
0.459 |
-2.947 |
C2orf55 |
chromosome 2 open reading frame 55 |
2 |
-98776740 |
AW249666 |
343990 |
2q11.2 |
Hs.469398 |
1 |
|
|
200720_s_at |
0.343 |
7.918 |
2.472 |
2.570e-02 |
0.517 |
-3.352 |
ACTR1A |
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
10 |
-104228976 |
AL532341 |
10121 |
10q24.32 |
Hs.153961 |
26 |
nucleotide binding protein binding ATP binding cytoplasm centrosome cytoskeleton dynactin complex vesicle-mediated transport |
|
213572_s_at |
0.668 |
6.314 |
3.914 |
1.349e-03 |
0.245 |
-0.854 |
SERPINB1 |
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
6 |
-2778732 |
AI554300 |
1992 |
6p25 |
Hs.381167 |
18 |
serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity |
|
210716_s_at |
0.536 |
7.410 |
2.238 |
4.056e-02 |
0.570 |
-3.732 |
CLIP1 |
CAP-GLY domain containing linker protein 1 |
12 |
-121321933 |
M97501 |
6249 |
12q24.3 |
Hs.524809 |
37 |
kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding |
|
200655_s_at |
0.494 |
10.516 |
4.067 |
9.861e-04 |
0.223 |
-0.588 |
CALM1 |
calmodulin 1 (phosphorylase kinase, delta) |
14 |
89933125 |
NM_006888 |
801 |
14q24-q31 |
Hs.282410 Hs.708270 |
181 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
55692_at |
ELMO2 |
engulfment and cell motility 2 |
20 |
-44428096 |
W22924 |
63916 |
20q13 |
Hs.210469 |
16 |
binding cytoplasm cytoskeleton phagocytosis apoptosis SH3 domain binding |
|
236305_at |
-0.495 |
5.307 |
-3.598 |
2.584e-03 |
0.287 |
-1.405 |
RFESD |
Rieske (Fe-S) domain containing |
5 |
95008236, 95008338 |
AI769245 |
317671 |
5q15 |
Hs.399758 |
2 |
iron ion binding electron carrier activity oxidoreductase activity metal ion binding 2 iron, 2 sulfur cluster binding oxidation reduction |
|
218858_at |
DEPDC6 |
DEP domain containing 6 |
8 |
120955080 |
NM_022783 |
64798 |
8q24.12 |
Hs.112981 |
11 |
protein binding intracellular negative regulation of protein kinase activity intracellular signaling cascade negative regulation of TOR signaling pathway regulation of apoptosis negative regulation of cell size |
|
217795_s_at |
0.240 |
7.794 |
2.253 |
3.942e-02 |
0.567 |
-3.708 |
TMEM43 |
transmembrane protein 43 |
3 |
14141440 |
W74580 |
79188 |
3p25.1 |
Hs.517817 |
18 |
nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane |
|
232983_s_at |
0.380 |
6.112 |
3.211 |
5.741e-03 |
0.357 |
-2.084 |
SERGEF |
secretion regulating guanine nucleotide exchange factor |
11 |
-17766171 |
AJ243951 |
26297 |
11p14.3 |
Hs.32470 |
7 |
guanyl-nucleotide exchange factor activity Ran guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm signal transduction negative regulation of protein secretion |
|
208816_x_at |
0.630 |
8.124 |
4.294 |
6.205e-04 |
0.211 |
-0.199 |
ANXA2P2 |
annexin A2 pseudogene 2 |
9 |
33614222 |
M62898 |
304 |
9p13 |
Hs.534301 |
2 |
angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm |
|
242663_at |
0.333 |
4.550 |
3.006 |
8.759e-03 |
0.394 |
-2.444 |
LOC148189 |
hypothetical LOC148189 |
19 |
-32973241 |
AA115127 |
148189 |
19q11 |
Hs.565253 |
2 |
|
|
226137_at |
ZFHX3 |
zinc finger homeobox 3 |
16 |
-71374286 |
AI288759 |
463 |
16q22.3-q23.1 |
Hs.598297 |
26 |
negative regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor activity, enhancer binding intracellular nucleus transcription factor complex mitochondrion regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity sequence-specific DNA binding metal ion binding |
|
218706_s_at |
0.937 |
5.188 |
3.946 |
1.262e-03 |
0.238 |
-0.797 |
GRAMD3 |
GRAM domain containing 3 |
5 |
125723686, 125786767, 125828685 |
AW575493 |
65983 |
5q23.2 |
Hs.363558 |
6 |
|
|
225395_s_at |
0.420 |
7.338 |
3.371 |
4.133e-03 |
0.323 |
-1.805 |
FAM120AOS |
family with sequence similarity 120A opposite strand |
9 |
-95248602 |
AI309997 |
158293 |
9q22.31 |
Hs.350364 Hs.709859 |
3 |
|
|
227226_at |
-0.426 |
4.460 |
-3.579 |
2.691e-03 |
0.290 |
-1.439 |
MRAP2 |
melanocortin 2 receptor accessory protein 2 |
6 |
84800138 |
AA418816 |
112609 |
6q14.2 |
Hs.370055 |
8 |
|
|
217755_at |
0.815 |
7.671 |
2.540 |
2.245e-02 |
0.500 |
-3.239 |
HN1 |
hematological and neurological expressed 1 |
17 |
-70642938, -70642938 |
NM_016185 |
51155 |
17q25.1 |
Hs.532803 Hs.713826 |
9 |
nucleus |
|
217165_x_at |
0.971 |
8.412 |
4.805 |
2.227e-04 |
0.172 |
0.655 |
MT1F |
metallothionein 1F |
16 |
55249355 |
M10943 |
4494 |
16q13 |
Hs.513626 |
20 |
copper ion binding cytoplasm biological_process zinc ion binding cadmium ion binding metal ion binding |
|
214757_at |
0.242 |
3.961 |
2.298 |
3.613e-02 |
0.558 |
-3.636 |
PMS2L2 |
postmeiotic segregation increased 2-like 2 pseudogene |
7 |
-74815899, 72114615 |
BG178274 |
5380 |
7q11-q22 |
Hs.292996 Hs.661055 Hs.675888 |
4 |
molecular_function ATP binding cellular_component mismatch repair biological_process mismatched DNA binding |
|
226615_at |
XPR1 |
xenotropic and polytropic retrovirus receptor |
1 |
178867768 |
BE439489 |
9213 |
1q25.1 |
Hs.227656 |
6 |
G-protein coupled receptor activity plasma membrane integral to plasma membrane G-protein coupled receptor protein signaling pathway |
|
208598_s_at |
0.267 |
7.922 |
2.400 |
2.961e-02 |
0.536 |
-3.471 |
HUWE1 |
HECT, UBA and WWE domain containing 1 |
X |
-53575796 |
NM_005703 |
10075 |
Xp11.22 |
Hs.136905 |
28 |
protein polyubiquitination DNA binding ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm protein modification process histone ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process cell differentiation |
Ubiquitin mediated proteolysis |
208370_s_at |
0.623 |
7.490 |
2.762 |
1.438e-02 |
0.447 |
-2.864 |
RCAN1 |
regulator of calcineurin 1 |
21 |
-34810653, -34810653, -34810653 |
NM_004414 |
1827 |
21q22.1-q22.2 21q22.12 |
Hs.282326 |
45 |
transcription factor activity protein binding nucleus cytoplasm signal transduction central nervous system development blood circulation response to mechanical stimulus calcium-mediated signaling response to estrogen stimulus regulation of phosphoprotein phosphatase activity skeletal muscle fiber development negative regulation of smooth muscle cell differentiation |
|
202158_s_at |
CUGBP2 |
CUG triplet repeat, RNA binding protein 2 |
10 |
11087264, 11099898, 11246998 |
NM_006561 |
10659 |
10p13 |
Hs.309288 |
25 |
nucleotide binding RNA binding protein binding nucleus cytoplasm mRNA processing regulation of heart contraction |
|
213479_at |
1.185 |
4.185 |
5.274 |
8.927e-05 |
0.162 |
1.403 |
NPTX2 |
neuronal pentraxin II |
7 |
98084532 |
U26662 |
4885 |
7q21.3-q22.1 |
Hs.3281 |
13 |
molecular_function calcium ion binding sugar binding extracellular region synaptic transmission |
|
225024_at |
RPRD1B |
regulation of nuclear pre-mRNA domain containing 1B |
20 |
36095361 |
AL117521 |
58490 |
20q11.21-q12 |
Hs.278839 |
7 |
|
|
231773_at |
0.757 |
7.221 |
2.839 |
1.231e-02 |
0.427 |
-2.733 |
ANGPTL1 |
angiopoietin-like 1 |
1 |
-177085292 |
BF002046 |
9068 |
1q25.2 |
Hs.591474 |
19 |
receptor binding extracellular region extracellular space signal transduction |
|
236313_at |
1.876 |
5.377 |
3.675 |
2.203e-03 |
0.276 |
-1.269 |
CDKN2B |
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
9 |
-21992901 |
AW444761 |
1030 |
9p21 |
Hs.72901 |
158 |
regulation of cyclin-dependent protein kinase activity G2/M transition of mitotic cell cycle cyclin-dependent protein kinase inhibitor activity protein binding cytoplasm cell cycle cell cycle arrest protein kinase binding positive regulation of transforming growth factor beta receptor signaling pathway G1/S transition checkpoint cellular response to extracellular stimulus cellular response to nutrient negative regulation of phosphorylation negative regulation of epithelial cell proliferation |
Cell cycle TGF-beta signaling pathway Pathways in cancer Small cell lung cancer |
239996_x_at |
ATP2A2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
12 |
109203414, 109203414 |
AI671237 |
488 |
12q23-q24.1 |
Hs.506759 |
84 |
nucleotide binding magnesium ion binding regulation of the force of heart contraction calcium-transporting ATPase activity calcium ion binding ATP binding membrane fraction microsome integral to plasma membrane ATP biosynthetic process cation transport cellular calcium ion homeostasis ER-nuclear signaling pathway cell adhesion metabolic process epidermis development membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances sarcoplasmic reticulum membrane negative regulation of heart contraction S100 alpha binding sarcoplasmic reticulum calcium ion transport |
Calcium signaling pathway Cardiac muscle contraction Alzheimer's disease Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
238049_at |
0.553 |
3.958 |
4.067 |
9.850e-04 |
0.223 |
-0.588 |
GRAMD3 |
GRAM domain containing 3 |
5 |
125723686, 125786767, 125828685 |
AW971198 |
65983 |
5q23.2 |
Hs.363558 |
6 |
|
|
204285_s_at |
0.964 |
4.893 |
4.287 |
6.289e-04 |
0.211 |
-0.210 |
PMAIP1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
18 |
55718171 |
AI857639 |
5366 |
18q21.32 |
Hs.96 |
36 |
release of cytochrome c from mitochondria protein binding mitochondrion induction of apoptosis activation of caspase activity cell structure disassembly during apoptosis virus-infected cell apoptosis response to dsRNA |
p53 signaling pathway |
231779_at |
0.565 |
6.289 |
2.966 |
9.492e-03 |
0.402 |
-2.512 |
IRAK2 |
interleukin-1 receptor-associated kinase 2 |
3 |
10181562 |
AI246590 |
3656 |
3p25.3 |
Hs.449207 |
15 |
regulation of cytokine-mediated signaling pathway MyD88-dependent toll-like receptor signaling pathway protein kinase activity NF-kappaB-inducing kinase activity ATP binding protein amino acid phosphorylation inflammatory response signal transduction I-kappaB kinase/NF-kappaB cascade cell surface lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity protein homodimerization activity protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway response to interleukin-1 |
Apoptosis Neurotrophin signaling pathway |
209014_at |
0.506 |
8.529 |
2.829 |
1.256e-02 |
0.429 |
-2.749 |
MAGED1 |
melanoma antigen family D, 1 |
X |
51562894, 51653437 |
AF217963 |
9500 |
Xp11.23 |
Hs.5258 |
29 |
transcription coactivator activity cytoplasm plasma membrane regulation of transcription from RNA polymerase II promoter identical protein binding regulation of apoptosis protein complex negative regulation of epithelial cell proliferation |
Neurotrophin signaling pathway |
200808_s_at |
-0.282 |
5.609 |
-3.394 |
3.940e-03 |
0.321 |
-1.764 |
ZYX |
zyxin |
7 |
142788481 |
NM_003461 |
7791 |
7q32 |
Hs.490415 |
38 |
stress fiber protein binding nucleus cytoplasm cytoskeleton plasma membrane integral to plasma membrane cell-cell adherens junction focal adhesion cell adhesion signal transduction cell-cell signaling zinc ion binding interspecies interaction between organisms metal ion binding |
Focal adhesion |
233669_s_at |
0.378 |
7.947 |
3.246 |
5.348e-03 |
0.351 |
-2.024 |
TRIM54 |
tripartite motif-containing 54 |
2 |
27359103 |
AA868267 |
57159 |
2p23.3 |
Hs.516036 |
5 |
signal transducer activity protein binding intracellular cytoplasm cytoskeleton microtubule microtubule associated complex microtubule-based process negative regulation of microtubule depolymerization signal transduction multicellular organismal development microtubule binding zinc ion binding Z disc cell differentiation metal ion binding |
|
235042_at |
1.131 |
9.868 |
3.223 |
5.605e-03 |
0.354 |
-2.064 |
XIRP1 |
xin actin-binding repeat containing 1 |
3 |
-39199710 |
AW755250 |
165904 |
3p22.2 |
Hs.447868 |
7 |
actin binding fascia adherens negative regulation of cell proliferation actin cytoskeleton organization cell junction regulation of membrane potential sarcomere organization cardiac muscle cell development |
|
212606_at |
0.334 |
6.864 |
2.467 |
2.596e-02 |
0.518 |
-3.361 |
WDFY3 |
WD repeat and FYVE domain containing 3 |
4 |
-85949008, -85809722, -85809722 |
AL536319 |
23001 |
4q21.23 |
Hs.480116 |
10 |
binding zinc ion binding membrane metal ion binding |
|
227395_at |
0.803 |
5.119 |
3.342 |
4.382e-03 |
0.328 |
-1.854 |
TBCEL |
tubulin folding cofactor E-like |
11 |
120400012, 120400022 |
BE672045 |
219899 |
11q23.3 |
Hs.504136 |
4 |
cytoplasm cytoskeleton |
|
213885_at |
-0.275 |
5.643 |
-3.186 |
6.045e-03 |
0.360 |
-2.128 |
TRIM3 |
tripartite motif-containing 3 |
11 |
-6426418 |
AA114843 |
10612 |
11p15.5 |
Hs.591992 |
11 |
intracellular cytoplasm early endosome nervous system development protein C-terminus binding zinc ion binding protein transport metal ion binding |
|
238228_at |
0.792 |
4.849 |
3.845 |
1.553e-03 |
0.254 |
-0.973 |
COG3 |
component of oligomeric golgi complex 3 |
13 |
44937071 |
AI732206 |
83548 |
13q14.13 |
Hs.507948 |
15 |
Golgi apparatus cis-Golgi network protein amino acid glycosylation intracellular protein transport ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport protein transporter activity membrane Golgi transport complex protein localization in organelle protein stabilization |
|
223960_s_at |
0.288 |
6.790 |
2.385 |
3.053e-02 |
0.541 |
-3.496 |
C16orf5 |
chromosome 16 open reading frame 5 |
16 |
-4500677 |
AF195661 |
29965 |
16p13.3 |
Hs.654653 |
6 |
molecular_function nucleus apoptosis induction of apoptosis biological_process tumor necrosis factor-mediated signaling pathway DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis |
|
205338_s_at |
-0.353 |
4.924 |
-3.273 |
5.060e-03 |
0.345 |
-1.977 |
DCT |
dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) |
13 |
-93889841 |
NM_001922 |
1638 |
13q32 |
Hs.301865 |
41 |
dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development |
Tyrosine metabolism Metabolic pathways Melanogenesis |
210813_s_at |
0.478 |
3.200 |
3.002 |
8.833e-03 |
0.394 |
-2.451 |
XRCC4 |
X-ray repair complementing defective repair in Chinese hamster cells 4 |
5 |
82409072 |
BC005259 |
7518 |
5q13-q14 |
Hs.567359 |
93 |
condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding nucleus nucleus cytosol DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development protein C-terminus binding response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA repair positive regulation of ligase activity |
Non-homologous end-joining |
230484_at |
-0.196 |
5.199 |
-2.699 |
1.633e-02 |
0.463 |
-2.971 |
CHDH |
choline dehydrogenase |
3 |
-53825427 |
AI741739 |
55349 |
3p21.1 |
Hs.126688 |
5 |
mitochondrion mitochondrial inner membrane alcohol metabolic process choline dehydrogenase activity FAD binding oxidation reduction |
Glycine, serine and threonine metabolism |
203560_at |
0.929 |
4.186 |
2.944 |
9.941e-03 |
0.412 |
-2.551 |
GGH |
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
8 |
-64090196 |
NM_003878 |
8836 |
8q12.3 |
Hs.78619 |
29 |
extracellular region extracellular space lysosome glutamine metabolic process hydrolase activity gamma-glutamyl-peptidase activity melanosome |
Folate biosynthesis |
220617_s_at |
ZNF532 |
zinc finger protein 532 |
18 |
54681040 |
NM_018181 |
55205 |
18q21.32 |
Hs.529023 Hs.607676 |
4 |
DNA binding intracellular nucleus nucleolus Golgi apparatus zinc ion binding regulation of transcription metal ion binding |
|
210887_s_at |
EVC |
Ellis van Creveld syndrome |
4 |
5763824 |
AF216185 |
2121 |
4p16 |
Hs.646899 Hs.670028 |
13 |
skeletal system development muscle organ development membrane integral to membrane |
|
212934_at |
UBXN2B |
UBX domain protein 2B |
8 |
59486376 |
AI245523 |
137886 |
8q12.1 |
Hs.155572 |
4 |
nucleus cytoplasm endoplasmic reticulum Golgi apparatus cytosol |
|
226334_s_at |
0.353 |
6.675 |
2.707 |
1.606e-02 |
0.459 |
-2.957 |
AHSA2 |
AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) |
2 |
61258324 |
AW117717 |
130872 |
2p15 |
Hs.655602 |
6 |
ATPase activator activity cytoplasm response to stress chaperone binding |
|
226003_at |
KIF21A |
kinesin family member 21A |
12 |
-37973296 |
AB051495 |
55605 |
12q12 |
Hs.374201 |
25 |
nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement |
|
215351_at |
RTCD1 |
RNA terminal phosphate cyclase domain 1 |
1 |
100504301 |
BG536504 |
8634 |
1p21.2 |
Hs.484222 |
7 |
nucleotide binding RNA binding RNA-3'-phosphate cyclase activity ATP binding nucleus nucleoplasm RNA processing |
|
201676_x_at |
0.292 |
10.708 |
3.602 |
2.565e-03 |
0.287 |
-1.399 |
PSMA1 |
proteasome (prosome, macropain) subunit, alpha type, 1 |
11 |
-14492087, -14482998, -14482998 |
NM_002786 |
5682 |
11p15.1 |
Hs.102798 Hs.445711 |
52 |
RNA binding threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex polysome ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
211316_x_at |
0.595 |
8.529 |
3.578 |
2.695e-03 |
0.290 |
-1.441 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AF009616 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
1557950_at |
0.366 |
6.619 |
2.407 |
2.919e-02 |
0.535 |
-3.459 |
SDCCAG1 |
serologically defined colon cancer antigen 1 |
14 |
-49320281 |
BF984340 |
9147 |
14q22 |
Hs.655964 |
8 |
nucleus cytoplasm |
|
204359_at |
0.488 |
8.107 |
2.322 |
3.452e-02 |
0.553 |
-3.598 |
FLRT2 |
fibronectin leucine rich transmembrane protein 2 |
14 |
85066240 |
NM_013231 |
23768 |
14q24-q32 |
Hs.533710 Hs.624735 Hs.719261 |
9 |
receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging |
|
225894_at |
0.411 |
11.477 |
2.551 |
2.200e-02 |
0.499 |
-3.222 |
SYNPO2 |
synaptopodin 2 |
4 |
120029443, 120029443 |
AL589603 |
171024 |
4q26 |
Hs.655519 |
14 |
actin binding protein binding nucleus cytoplasm |
|
238039_at |
0.465 |
4.326 |
3.694 |
2.121e-03 |
0.276 |
-1.237 |
LOC728769 |
hypothetical protein LOC728769 |
5 |
|
BG180437 |
728769 |
5q14.1 |
Hs.586193 |
|
|
|
201939_at |
0.687 |
5.403 |
3.040 |
8.156e-03 |
0.387 |
-2.383 |
PLK2 |
polo-like kinase 2 (Drosophila) |
5 |
-57785566 |
NM_006622 |
10769 |
5q12.1-q13.2 |
Hs.398157 Hs.658132 |
20 |
nucleotide binding mitotic cell cycle protein serine/threonine kinase activity signal transducer activity protein binding ATP binding protein amino acid phosphorylation transferase activity polo kinase kinase activity positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
204781_s_at |
FAS |
Fas (TNF receptor superfamily, member 6) |
10 |
90740267, 90740267 |
NM_000043 |
355 |
10q24.1 |
Hs.244139 |
589 |
immunoglobulin production renal system process transmembrane receptor activity extracellular region soluble fraction cytosol plasma membrane plasma membrane protein complex assembly anti-apoptosis activation-induced cell death of T cells inflammatory cell apoptosis transformed cell apoptosis immune response signal transduction induction of apoptosis via death domain receptors activation of pro-apoptotic gene products response to toxin external side of plasma membrane gene expression positive regulation of necrotic cell death integral to membrane B cell mediated immunity kinase binding death-inducing signaling complex identical protein binding negative thymic T cell selection regulation of lymphocyte differentiation regulation of myeloid cell differentiation spleen development negative regulation of B cell activation protein homooligomerization response to glucocorticoid stimulus response to protein stimulus |
MAPK signaling pathway Cytokine-cytokine receptor interaction p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Type I diabetes mellitus Alzheimer's disease Pathways in cancer Autoimmune thyroid disease Allograft rejection Graft-versus-host disease |
226353_at |
SPPL2A |
signal peptide peptidase-like 2A |
15 |
-48787028 |
AI674647 |
84888 |
15q21.2 |
Hs.401537 |
12 |
aspartic-type endopeptidase activity peptidase activity membrane integral to membrane |
|
221052_at |
-0.349 |
3.135 |
-4.045 |
1.031e-03 |
0.225 |
-0.626 |
TDRKH |
tudor and KH domain containing |
1 |
-150012579, -150010664 |
NM_006862 |
11022 |
1q21 |
Hs.144439 |
8 |
RNA binding |
|
221821_s_at |
C12orf41 |
chromosome 12 open reading frame 41 |
12 |
-47333261 |
AK022732 |
54934 |
12q13.11 |
Hs.505412 |
8 |
|
|
226787_at |
0.252 |
5.360 |
2.258 |
3.905e-02 |
0.567 |
-3.700 |
ZNF18 |
zinc finger protein 18 |
17 |
-11821486 |
BF966015 |
7566 |
17p11.2 |
Hs.370473 |
8 |
transcription factor activity intracellular nucleus nucleolus cytoplasm Golgi apparatus plasma membrane regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
208015_at |
0.487 |
5.324 |
3.349 |
4.324e-03 |
0.328 |
-1.843 |
SMAD1 |
SMAD family member 1 |
4 |
146622400, 146623406 |
NM_015583 |
4086 |
4q31 |
Hs.604588 |
118 |
MAPKKK cascade mesodermal cell fate commitment osteoblast fate commitment transcription factor activity RNA polymerase II transcription factor activity receptor signaling protein activity intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol inflammatory response signal transduction transforming growth factor beta receptor signaling pathway SMAD protein complex assembly gamete generation negative regulation of cell proliferation embryonic pattern specification positive regulation of gene expression integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity midbrain development hindbrain development primary microRNA processing homeostatic process identical protein binding positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter co-SMAD binding |
TGF-beta signaling pathway |
1555778_a_at |
1.455 |
3.054 |
3.760 |
1.852e-03 |
0.271 |
-1.122 |
POSTN |
periostin, osteoblast specific factor |
13 |
-37034719 |
AY140646 |
10631 |
13q13.3 |
Hs.136348 |
38 |
skeletal system development protein binding extracellular region proteinaceous extracellular matrix cell adhesion heparin binding |
|
36829_at |
PER1 |
period homolog 1 (Drosophila) |
17 |
-7984512 |
AF022991 |
5187 |
17p13.1-p12 |
Hs.445534 |
54 |
signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm entrainment of circadian clock negative regulation of transcription |
Circadian rhythm - mammal |
36553_at |
0.538 |
6.751 |
2.507 |
2.399e-02 |
0.509 |
-3.295 |
ASMTL |
acetylserotonin O-methyltransferase-like |
X, Y |
-1482031, -1482031 |
AA669799 |
8623 |
Xp22.3 Yp11.3 |
Hs.533514 |
10 |
cellular_component cytoplasm acetylserotonin O-methyltransferase activity melatonin biosynthetic process |
|
239390_at |
GTDC1 |
glycosyltransferase-like domain containing 1 |
2 |
-144420052, -144420050 |
BE327650 |
79712 |
2q22.3 |
Hs.44780 |
3 |
biosynthetic process transferase activity, transferring glycosyl groups |
|
232510_s_at |
0.366 |
6.473 |
2.922 |
1.039e-02 |
0.418 |
-2.588 |
DPP3 |
dipeptidyl-peptidase 3 |
11 |
66004455 |
AW250952 |
10072 |
11q12-q13.1 |
Hs.502914 |
29 |
aminopeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity dipeptidyl-peptidase activity zinc ion binding metal ion binding |
|
221483_s_at |
0.320 |
9.330 |
2.811 |
1.303e-02 |
0.433 |
-2.780 |
ARPP19 |
cAMP-regulated phosphoprotein, 19kDa |
15 |
-50626723 |
AF084555 |
10776 |
15q21.2 |
Hs.512908 |
10 |
receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import |
|
223044_at |
0.521 |
9.868 |
3.614 |
2.499e-03 |
0.287 |
-1.376 |
SLC40A1 |
solute carrier family 40 (iron-regulated transporter), member 1 |
2 |
-190133560 |
AL136944 |
30061 |
2q32 |
Hs.643005 |
73 |
iron ion transmembrane transporter activity iron ion binding cytoplasm plasma membrane integral to plasma membrane ion transport iron ion transport cellular iron ion homeostasis synaptic vesicle anatomical structure morphogenesis |
|
223908_at |
0.437 |
4.374 |
2.201 |
4.357e-02 |
0.578 |
-3.791 |
HDAC8 |
histone deacetylase 8 |
X |
-71466090 |
AF212246 |
55869 |
Xq13 |
Hs.310536 |
23 |
histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter nuclear chromosome histone deacetylase activity nucleus cytoplasm chromatin assembly or disassembly transcription factor binding chromatin modification histone deacetylation hydrolase activity regulation of transcription |
|
229412_at |
0.486 |
5.685 |
2.917 |
1.051e-02 |
0.418 |
-2.598 |
TAF8 |
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa |
6 |
42126228 |
AA641254 |
129685 |
6p21.1 |
Hs.520122 |
17 |
inner cell mass cell proliferation DNA binding protein binding nucleus transcription factor TFIID complex cytoplasm multicellular organismal development transcription activator activity cell differentiation regulation of transcription regulation of fat cell differentiation positive regulation of transcription, DNA-dependent |
|
215716_s_at |
ATP2B1 |
ATPase, Ca++ transporting, plasma membrane 1 |
12 |
-88505956 |
L14561 |
490 |
12q21.3 |
Hs.506276 |
38 |
nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
Calcium signaling pathway |
221823_at |
0.404 |
5.944 |
2.243 |
4.023e-02 |
0.569 |
-3.725 |
C5orf30 |
chromosome 5 open reading frame 30 |
5 |
102622340 |
AL565741 |
90355 |
5q21.1 |
Hs.482976 |
4 |
|
|
215667_x_at |
0.324 |
5.992 |
2.546 |
2.221e-02 |
0.500 |
-3.230 |
PMS2L1 |
postmeiotic segregation increased 2-like 1 pseudogene |
7 |
-99756198 |
AI375694 |
5379 |
7q22.1 |
Hs.634244 Hs.661055 Hs.709266 |
7 |
molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding |
|
230876_at |
LOC169834 |
hypothetical protein LOC169834 |
9 |
-114799220 |
AI827906 |
169834 |
9q32 |
Hs.192877 |
1 |
|
|
226942_at |
PHF20L1 |
PHD finger protein 20-like 1 |
8 |
133856785, 133856785, 133856785 |
AI742668 |
51105 |
8q24.22 |
Hs.304362 |
4 |
nucleic acid binding protein binding zinc ion binding metal ion binding |
|
205151_s_at |
0.631 |
6.215 |
4.013 |
1.101e-03 |
0.227 |
-0.681 |
KIAA0644 |
KIAA0644 gene product |
7 |
-28959498 |
NM_014817 |
9865 |
7p14.3 |
Hs.719240 |
4 |
protein binding membrane integral to membrane |
|
214151_s_at |
0.458 |
7.368 |
3.101 |
7.201e-03 |
0.374 |
-2.277 |
CCPG1 |
cell cycle progression 1 |
15 |
-53434729, -53434729 |
AU144243 |
9236 |
15q21.1 |
Hs.285051 |
5 |
cell cycle membrane integral to membrane |
|
207675_x_at |
-0.231 |
4.688 |
-2.284 |
3.711e-02 |
0.562 |
-3.658 |
ARTN |
artemin |
1 |
44171578, 44173617, 44174240 |
NM_003976 |
9048 |
1p33-p32 |
Hs.632404 |
14 |
extracellular region signal transduction neuroblast proliferation growth factor activity |
|
239183_at |
0.837 |
6.216 |
3.149 |
6.531e-03 |
0.364 |
-2.194 |
ANGPTL1 |
angiopoietin-like 1 |
1 |
-177085292 |
W67461 |
9068 |
1q25.2 |
Hs.591474 |
19 |
receptor binding extracellular region extracellular space signal transduction |
|
212566_at |
0.310 |
10.545 |
2.448 |
2.694e-02 |
0.525 |
-3.392 |
MAP4 |
microtubule-associated protein 4 |
3 |
-47989573, -47867183, -47867183 |
AL523310 |
4134 |
3p21 |
Hs.517949 |
40 |
structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
209281_s_at |
ATP2B1 |
ATPase, Ca++ transporting, plasma membrane 1 |
12 |
-88505956 |
M95541 |
490 |
12q21.3 |
Hs.506276 |
38 |
nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding calmodulin binding ATP binding plasma membrane integral to plasma membrane ATP biosynthetic process cation transport calcium ion transport metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
Calcium signaling pathway |
218178_s_at |
0.823 |
8.778 |
4.247 |
6.827e-04 |
0.211 |
-0.279 |
CHMP1B |
chromatin modifying protein 1B |
18 |
11841388 |
NM_020412 |
57132 |
18p11.21 |
Hs.656244 |
16 |
cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division |
Endocytosis |
213152_s_at |
SFRS2B |
splicing factor, arginine/serine-rich 2B |
11 |
94439703 |
AI343248 |
10929 |
11q22 |
Hs.476680 Hs.713908 |
6 |
nucleotide binding RNA binding nucleus mRNA processing RNA splicing |
|
203485_at |
0.629 |
5.012 |
3.798 |
1.712e-03 |
0.267 |
-1.056 |
RTN1 |
reticulon 1 |
14 |
-59132446, -59132446, -59132446 |
NM_021136 |
6252 |
14q23.1 |
Hs.368626 |
23 |
signal transducer activity endoplasmic reticulum signal transduction membrane integral to membrane integral to endoplasmic reticulum membrane neuron differentiation |
|
1552887_at |
C10orf27 |
chromosome 10 open reading frame 27 |
10 |
-72201000 |
NM_152710 |
219793 |
10q22.1 |
Hs.386698 |
5 |
protein binding cytoplasm cytosol multicellular organismal development spermatogenesis cell differentiation |
|
235341_at |
-0.336 |
4.596 |
-3.726 |
1.986e-03 |
0.273 |
-1.181 |
DNAJC3 |
DnaJ (Hsp40) homolog, subfamily C, member 3 |
13 |
95127402 |
AL119957 |
5611 |
13q32.1 |
Hs.59214 |
19 |
protein kinase inhibitor activity binding cytoplasm endoplasmic reticulum response to unfolded protein response to virus heat shock protein binding |
|
213215_at |
0.327 |
7.231 |
2.434 |
2.769e-02 |
0.527 |
-3.415 |
AP3S2 |
adaptor-related protein complex 3, sigma 2 subunit |
15 |
-88174834 |
AI910895 |
10239 |
15q26.1 |
Hs.632161 |
14 |
protein binding Golgi apparatus intracellular protein transport protein transporter activity membrane vesicle-mediated transport membrane coat cytoplasmic vesicle |
Lysosome |
1555976_s_at |
1.076 |
6.343 |
3.558 |
2.810e-03 |
0.294 |
-1.476 |
MYL12A |
myosin, light chain 12A, regulatory, non-sarcomeric |
18 |
3237527 |
BU676221 |
10627 |
18p11.31 |
Hs.190086 |
9 |
motor activity calcium ion binding protein binding myosin complex |
Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton |
219366_at |
AVEN |
apoptosis, caspase activation inhibitor |
15 |
-31945719 |
NM_020371 |
57099 |
15q13.1 |
Hs.555966 |
10 |
protein binding intracellular membrane fraction apoptosis anti-apoptosis membrane |
|
204324_s_at |
GOLIM4 |
golgi integral membrane protein 4 |
3 |
-169210347 |
NM_014498 |
27333 |
3q26.2 |
Hs.143600 |
10 |
nucleus endosome Golgi apparatus Golgi lumen cis-Golgi network transport membrane integral to membrane endocytic vesicle |
|
238462_at |
0.451 |
2.700 |
2.888 |
1.113e-02 |
0.425 |
-2.647 |
UBASH3B |
ubiquitin associated and SH3 domain containing, B |
11 |
122031607 |
AI418293 |
84959 |
11q24.1 |
Hs.444075 |
15 |
nucleus cytoplasm |
|
200671_s_at |
0.571 |
5.770 |
3.848 |
1.543e-03 |
0.254 |
-0.967 |
SPTBN1 |
spectrin, beta, non-erythrocytic 1 |
2 |
54536957, 54639034 |
N92501 |
6711 |
2p21 |
Hs.503178 Hs.705692 |
46 |
actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping |
|
225997_at |
MOBKL1A |
MOB1, Mps One Binder kinase activator-like 1A (yeast) |
4 |
71986927 |
AL162039 |
92597 |
4q13.3 |
Hs.700445 Hs.719746 |
6 |
protein binding nucleus cytoplasm zinc ion binding kinase activator activity kinase binding protein amino acid autophosphorylation metal ion binding |
|
243318_at |
DCAF8 |
DDB1 and CUL4 associated factor 8 |
1 |
-158475636, -158475636, -158452128, -158452128 |
AI208342 |
50717 |
1q22-q23 |
Hs.632447 |
10 |
protein binding |
|
217838_s_at |
0.521 |
6.515 |
3.321 |
4.584e-03 |
0.333 |
-1.893 |
EVL |
Enah/Vasp-like |
14 |
99601503 |
NM_016337 |
51466 |
14q32.2 |
Hs.125867 |
24 |
actin binding profilin binding cytoplasm cytoskeleton focal adhesion cell surface receptor linked signal transduction nervous system development actin polymerization or depolymerization organ morphogenesis SH3 domain binding lamellipodium |
|
1555427_s_at |
0.524 |
5.246 |
2.911 |
1.062e-02 |
0.418 |
-2.607 |
SYNCRIP |
synaptotagmin binding, cytoplasmic RNA interacting protein |
6 |
-86380411, -86380411, -86374221, -86374221, -86374221, -86374221 |
AY034482 |
10492 |
6q14-q15 |
Hs.571177 |
33 |
nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms |
|
243492_at |
0.337 |
5.594 |
2.239 |
4.052e-02 |
0.570 |
-3.731 |
THEM4 |
thioesterase superfamily member 4 |
1 |
-150112683 |
AW972653 |
117145 |
1q21 |
Hs.164070 |
8 |
cytoplasm plasma membrane ruffle membrane cell projection |
|
206633_at |
2.819 |
7.373 |
3.885 |
1.431e-03 |
0.250 |
-0.903 |
CHRNA1 |
cholinergic receptor, nicotinic, alpha 1 (muscle) |
2 |
-175320568 |
NM_000079 |
1134 |
2q24-q32 |
Hs.434479 |
43 |
skeletal muscle contraction nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport signal transduction neuromuscular synaptic transmission neuromuscular junction development cell surface acetylcholine receptor activity integral to membrane regulation of action potential in neuron cell junction neuromuscular junction regulation of membrane potential postsynaptic membrane muscle maintenance skeletal muscle tissue growth neuromuscular process neuron maintenance |
|
204742_s_at |
PDS5B |
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) |
13 |
32058591 |
NM_015032 |
23047 |
13q12.3 |
Hs.716441 |
15 |
chromatin DNA binding ATP binding nucleus cell cycle mitotic sister chromatid cohesion mitosis negative regulation of cell proliferation identical protein binding cell division |
|
203836_s_at |
-0.497 |
6.368 |
-2.553 |
2.190e-02 |
0.499 |
-3.218 |
MAP3K5 |
mitogen-activated protein kinase kinase kinase 5 |
6 |
-136919879 |
D84476 |
4217 |
6q22.33 |
Hs.186486 |
108 |
MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding protein amino acid phosphorylation apoptosis activation of JUN kinase activity induction of apoptosis by extracellular signals caspase activator activity transferase activity protein homodimerization activity interspecies interaction between organisms |
MAPK signaling pathway Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) |
221029_s_at |
WNT5B |
wingless-type MMTV integration site family, member 5B |
12 |
1596482, 1608672 |
NM_030775 |
81029 |
12p13.3 |
Hs.306051 |
11 |
signal transducer activity extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway multicellular organismal development |
Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma |
218934_s_at |
0.591 |
10.768 |
2.998 |
8.894e-03 |
0.395 |
-2.457 |
HSPB7 |
heat shock 27kDa protein family, member 7 (cardiovascular) |
1 |
-16213109 |
NM_014424 |
27129 |
1p36.23-p34.3 |
Hs.502612 |
7 |
response to unfolded protein regulation of heart contraction protein C-terminus binding response to heat |
|
226230_at |
0.418 |
6.581 |
2.618 |
1.922e-02 |
0.489 |
-3.108 |
SMEK2 |
SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
2 |
-55629017 |
AA541716 |
57223 |
2p16.1 |
Hs.516182 |
16 |
protein binding nucleus cytoplasm centrosome |
|
207717_s_at |
PKP2 |
plakophilin 2 |
12 |
-32834946 |
NM_004572 |
5318 |
12p11 |
Hs.164384 |
29 |
protein binding nucleus cytoskeleton plasma membrane integral to membrane cell-cell adhesion desmosome |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
229459_at |
0.718 |
2.636 |
5.134 |
1.171e-04 |
0.162 |
1.183 |
FAM19A5 |
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 |
22 |
47263951, 47350781 |
AV723914 |
25817 |
22q13.32 |
Hs.436854 Hs.632788 |
8 |
extracellular region membrane integral to membrane |
|
224879_at |
-0.538 |
10.010 |
-2.671 |
1.728e-02 |
0.471 |
-3.019 |
C9orf123 |
chromosome 9 open reading frame 123 |
9 |
-7786490 |
BF315994 |
90871 |
9p24.1 |
Hs.7517 |
4 |
membrane integral to membrane |
|
212539_at |
CHD1L |
chromodomain helicase DNA binding protein 1-like |
1 |
145180914 |
AI422099 |
9557 |
1q12 |
Hs.191164 |
12 |
nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity |
|
200962_at |
-0.880 |
5.997 |
-3.634 |
2.399e-03 |
0.284 |
-1.342 |
RPL31 |
ribosomal protein L31 |
2 |
100985122, 100985122 |
AI348010 |
6160 |
2q11.2 |
Hs.469473 |
21 |
RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome translational elongation cytosolic large ribosomal subunit |
Ribosome |
211808_s_at |
-0.217 |
5.027 |
-2.511 |
2.379e-02 |
0.509 |
-3.288 |
CREBBP |
CREB binding protein |
16 |
-3715056 |
U85962 |
1387 |
16p13.3 |
Hs.459759 |
399 |
histone acetyltransferase complex response to hypoxia p53 binding transcription factor activity transcription coactivator activity transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent protein complex assembly signal transduction zinc ion binding acetyltransferase activity histone acetylation transferase activity N-terminal peptidyl-lysine acetylation homeostatic process interspecies interaction between organisms positive regulation of transcription positive regulation of transcription metal ion binding MyoD binding |
Cell cycle Wnt signaling pathway Notch signaling pathway TGF-beta signaling pathway Adherens junction Jak-STAT signaling pathway Long-term potentiation Melanogenesis Huntington's disease Pathways in cancer Renal cell carcinoma Prostate cancer |
204407_at |
0.764 |
3.787 |
2.894 |
1.101e-02 |
0.424 |
-2.638 |
TTF2 |
transcription termination factor, RNA polymerase II |
1 |
117404471 |
AF080255 |
8458 |
1p22 |
Hs.486818 |
12 |
nucleotide binding DNA binding RNA polymerase II transcription termination factor activity helicase activity ATP binding nucleus spliceosomal complex cytoplasm transcription termination mRNA processing transcription elongation factor complex ATP-dependent helicase activity DNA-dependent ATPase activity zinc ion binding RNA splicing hydrolase activity regulation of transcription |
|
1552701_a_at |
CARD16 |
caspase recruitment domain family, member 16 |
11 |
-104417262 |
NM_052889 |
114769 |
|
Hs.348365 |
8 |
cysteine-type endopeptidase activity cysteine-type endopeptidase inhibitor activity protein binding intracellular proteolysis peptidase inhibitor activity regulation of apoptosis |
|
226066_at |
0.370 |
8.536 |
2.625 |
1.894e-02 |
0.488 |
-3.096 |
MITF |
microphthalmia-associated transcription factor |
3 |
69871322, 69895651, 69998131, 70010945, 70068442 |
AL117653 |
4286 |
3p14.2-p14.1 |
Hs.166017 Hs.618266 |
93 |
DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation |
Melanogenesis Pathways in cancer Melanoma |
225108_at |
0.545 |
5.444 |
2.676 |
1.709e-02 |
0.470 |
-3.010 |
AGPS |
alkylglycerone phosphate synthase |
2 |
177965716 |
BF111719 |
8540 |
2q31.2 |
Hs.516543 |
19 |
peroxisome peroxisomal membrane cytosol alkylglycerone-phosphate synthase activity lipid biosynthetic process membrane oxidoreductase activity transferase activity FAD binding |
Ether lipid metabolism Metabolic pathways |
1552649_a_at |
0.405 |
4.033 |
2.862 |
1.175e-02 |
0.426 |
-2.693 |
RFFL |
ring finger and FYVE-like domain containing 1 |
17 |
-30360243, -30360243 |
NM_057178 |
117584 |
17q12 |
Hs.13680 |
11 |
protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding |
|
217722_s_at |
0.280 |
11.404 |
2.660 |
1.767e-02 |
0.473 |
-3.038 |
NGRN |
neugrin, neurite outgrowth associated |
15 |
88609898 |
NM_016645 |
51335 |
15q26.1 |
Hs.715556 Hs.716378 |
2 |
molecular_function nucleus multicellular organismal development nervous system development neuron differentiation |
|
235093_at |
PEX13 |
peroxisomal biogenesis factor 13 |
2 |
61098315 |
BE564430 |
5194 |
2p14-p16 |
Hs.161377 |
21 |
fatty acid alpha-oxidation neuron migration suckling behavior protein binding membrane fraction peroxisome peroxisomal membrane integral to peroxisomal membrane locomotory behavior protein transport membrane integral to membrane protein import into peroxisome matrix, docking protein import into peroxisome matrix, docking cerebral cortex cell migration microtubule-based peroxisome localization |
|
217717_s_at |
0.360 |
8.101 |
2.659 |
1.771e-02 |
0.473 |
-3.040 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide |
20 |
42947757 |
BF246499 |
7529 |
20q13.1 |
Hs.643544 |
109 |
cytoplasm cytosol protein targeting Ras protein signal transduction activation of pro-apoptotic gene products enzyme binding protein domain specific binding negative regulation of protein amino acid dephosphorylation melanosome positive regulation of catalytic activity perinuclear region of cytoplasm |
Cell cycle Neurotrophin signaling pathway |
201806_s_at |
ATXN2L |
ataxin 2-like |
16 |
28741914, 28741914 |
NM_007245 |
11273 |
16p11 |
Hs.460499 |
14 |
molecular_function cellular_component biological_process membrane |
|
200998_s_at |
0.266 |
6.621 |
2.224 |
4.167e-02 |
0.573 |
-3.754 |
CKAP4 |
cytoskeleton-associated protein 4 |
12 |
-105155789 |
AW029619 |
10970 |
12q23.3 |
Hs.714862 Hs.74368 |
22 |
membrane fraction endoplasmic reticulum membrane integral to membrane |
|
1564383_s_at |
-0.214 |
3.139 |
-2.565 |
2.139e-02 |
0.497 |
-3.199 |
FLJ35934 |
FLJ35934 protein |
17 |
|
AK093253 |
400579 |
17p11.2 |
Hs.375092 |
2 |
|
|
209613_s_at |
-0.938 |
6.961 |
-2.459 |
2.635e-02 |
0.521 |
-3.373 |
ADH1B |
alcohol dehydrogenase 1B (class I), beta polypeptide |
4 |
-100446549 |
M21692 |
125 |
4q21-q23 |
Hs.4 |
193 |
alcohol dehydrogenase (NAD) activity binding cytoplasm ethanol oxidation zinc ion binding oxidoreductase activity metal ion binding oxidation reduction |
Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways |
235348_at |
0.476 |
4.294 |
2.812 |
1.300e-02 |
0.432 |
-2.779 |
ABHD13 |
abhydrolase domain containing 13 |
13 |
107668763 |
AA404347 |
84945 |
13q33.3 |
Hs.183528 |
6 |
membrane integral to membrane hydrolase activity |
|
213065_at |
0.367 |
6.431 |
2.972 |
9.375e-03 |
0.401 |
-2.501 |
ZFC3H1 |
zinc finger, C3H1-type containing |
12 |
-70289648 |
AB011118 |
196441 |
12q21.1 |
Hs.527874 |
4 |
binding intracellular RNA processing zinc ion binding metal ion binding |
|
203909_at |
SLC9A6 |
solute carrier family 9 (sodium/hydrogen exchanger), member 6 |
X |
134895251 |
NM_006359 |
10479 |
Xq26.3 |
Hs.62185 |
11 |
mitochondrion endosome endoplasmic reticulum membrane microsome plasma membrane cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity integral to membrane sodium ion binding early endosome membrane recycling endosome membrane |
Cardiac muscle contraction |
202753_at |
0.284 |
9.889 |
3.209 |
5.774e-03 |
0.357 |
-2.089 |
PSMD6 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 |
3 |
-63971270 |
NM_014814 |
9861 |
3p14.1 |
Hs.152536 |
35 |
proteasome complex protein binding cytosol proteolysis ATPase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
209681_at |
-1.283 |
8.790 |
-2.848 |
1.209e-02 |
0.426 |
-2.717 |
SLC19A2 |
solute carrier family 19 (thiamine transporter), member 2 |
1 |
-167699772 |
AF153330 |
10560 |
1q23.3 |
Hs.30246 |
32 |
folic acid binding cytoplasm plasma membrane transport folic acid transporter activity reduced folate carrier activity thiamin transmembrane transporter activity thiamin transport integral to membrane thiamin and derivative metabolic process |
|
203820_s_at |
IGF2BP3 |
insulin-like growth factor 2 mRNA binding protein 3 |
7 |
-23316352 |
NM_006547 |
10643 |
7p11 |
Hs.700696 |
37 |
nucleotide binding RNA binding nucleus cytoplasm anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process translation regulator activity mRNA 5'-UTR binding |
|
207169_x_at |
1.084 |
6.635 |
4.211 |
7.349e-04 |
0.211 |
-0.341 |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
6 |
30959839, 30960305, 30964443, 2300465, 2300931, 2305069, 2098794, 2099260, 2103398 |
NM_001954 |
780 |
6p21.3 |
Hs.631988 |
60 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding extracellular region integral to plasma membrane protein amino acid phosphorylation cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity |
|
211045_s_at |
KCNH6 |
potassium voltage-gated channel, subfamily H (eag-related), member 6 |
17 |
58954426, 58954426 |
BC006334 |
81033 |
17q23.3 |
Hs.591177 |
6 |
voltage-gated ion channel activity voltage-gated potassium channel activity regulation of transcription, DNA-dependent ion transport potassium ion transport signal transduction membrane integral to membrane potassium ion binding |
|
215932_at |
-0.223 |
3.175 |
-2.234 |
4.087e-02 |
0.570 |
-3.738 |
MAGEC2 |
melanoma antigen family C, 2 |
X |
-141117795 |
AL031073 |
51438 |
Xq27 |
Hs.123536 |
14 |
nucleus cytoplasm |
|
1552309_a_at |
0.317 |
12.027 |
2.361 |
3.199e-02 |
0.545 |
-3.535 |
NEXN |
nexilin (F actin binding protein) |
1 |
78126787 |
NM_144573 |
91624 |
1p31.1 |
Hs.612385 |
6 |
cytoplasm cytoskeleton cell-substrate adherens junction cell junction regulation of cell migration actin filament binding regulation of cytoskeleton organization |
|
214297_at |
0.806 |
4.260 |
3.878 |
1.453e-03 |
0.250 |
-0.916 |
CSPG4 |
chondroitin sulfate proteoglycan 4 |
15 |
-73753717 |
BE857703 |
1464 |
15q24.2 |
Hs.513044 |
34 |
angiogenesis signal transducer activity receptor signaling protein tyrosine phosphatase signaling protein activity protein binding plasma membrane integral to plasma membrane signal transduction multicellular organismal development receptor signaling protein tyrosine kinase signaling protein activity cell surface cell differentiation cell projection tissue remodeling |
|
212446_s_at |
LASS6 |
LAG1 homolog, ceramide synthase 6 |
2 |
169021080 |
AI658534 |
253782 |
2q24.3 |
Hs.506829 Hs.718403 |
5 |
transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding ceramide biosynthetic process sphingosine N-acyltransferase activity |
|
225145_at |
0.273 |
5.687 |
2.332 |
3.381e-02 |
0.552 |
-3.581 |
NCOA5 |
nuclear receptor coactivator 5 |
20 |
-44123032 |
AB046857 |
57727 |
20q12-q13.12 |
Hs.654991 |
8 |
aminoacyl-tRNA ligase activity ATP binding nucleus translation regulation of transcription |
|
224832_at |
DUSP16 |
dual specificity phosphatase 16 |
12 |
-12520097 |
AB051487 |
80824 |
12p13 |
Hs.536535 |
12 |
inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive |
MAPK signaling pathway |
227766_at |
LIG4 |
ligase IV, DNA, ATP-dependent |
13 |
-107657792, -107657792, -107657792 |
AI829314 |
3981 |
13q33-q34 |
Hs.166091 |
82 |
single strand break repair nucleotide binding magnesium ion binding condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding DNA ligase (ATP) activity ATP binding intracellular nucleus cytoplasm plasma membrane focal adhesion DNA-dependent protein kinase-DNA ligase 4 complex DNA replication nucleotide-excision repair, DNA gap filling double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus cell cycle central nervous system development protein C-terminus binding cell proliferation response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination T cell receptor V(D)J recombination somatic stem cell maintenance negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA recombination DNA ligation during DNA repair DNA ligation during DNA repair chromosome organization cell division |
Non-homologous end-joining |
209508_x_at |
0.516 |
7.396 |
3.600 |
2.576e-03 |
0.287 |
-1.402 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AF005774 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
208865_at |
0.275 |
9.179 |
2.138 |
4.910e-02 |
0.590 |
-3.889 |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
BG534245 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
213546_at |
0.552 |
6.584 |
2.407 |
2.925e-02 |
0.535 |
-3.460 |
DKFZP586I1420 |
hypothetical protein DKFZp586I1420 |
7 |
30376190 |
AL050378 |
222161 |
7p14.3 |
Hs.112423 |
2 |
|
|
202222_s_at |
0.273 |
11.468 |
2.285 |
3.705e-02 |
0.562 |
-3.657 |
DES |
desmin |
2 |
219991342 |
NM_001927 |
1674 |
2q35 |
Hs.594952 |
57 |
structural constituent of cytoskeleton protein binding intracellular insoluble fraction cytoplasm cytoskeleton muscle contraction cytoskeleton organization regulation of heart contraction Z disc sarcolemma contractile fiber type III intermediate filament synapse |
Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
202590_s_at |
-0.355 |
8.502 |
-2.421 |
2.842e-02 |
0.532 |
-3.436 |
PDK2 |
pyruvate dehydrogenase kinase, isozyme 2 |
17 |
45527694 |
AL574319 |
5164 |
17q21.33 |
Hs.256667 |
28 |
two-component sensor activity nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity protein binding ATP binding nucleus nucleolus mitochondrion mitochondrial matrix carbohydrate metabolic process glucose metabolic process signal transduction transferase activity peptidyl-histidine phosphorylation |
|
219882_at |
0.447 |
5.188 |
2.770 |
1.417e-02 |
0.445 |
-2.851 |
TTLL7 |
tubulin tyrosine ligase-like family, member 7 |
1 |
-84107644 |
NM_024686 |
79739 |
1p31.1 |
Hs.445826 |
7 |
tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process multicellular organismal development nervous system development ligase activity cell differentiation dendrite perikaryon |
|
204745_x_at |
0.877 |
8.513 |
4.749 |
2.490e-04 |
0.172 |
0.563 |
MT1G |
metallothionein 1G |
16 |
-55258153 |
NM_005950 |
4495 |
16q13 |
Hs.433391 |
17 |
copper ion binding protein binding zinc ion binding cadmium ion binding metal ion binding |
|
206662_at |
0.901 |
9.632 |
4.386 |
5.156e-04 |
0.204 |
-0.043 |
GLRX |
glutaredoxin (thioltransferase) |
5 |
-95175308 |
NM_002064 |
2745 |
5q14 |
Hs.28988 Hs.712696 |
47 |
cytoplasm cytosol transport electron carrier activity protein disulfide oxidoreductase activity glutathione disulfide oxidoreductase activity electron transport chain cell redox homeostasis protein N-terminus binding |
|
209841_s_at |
1.195 |
4.453 |
3.052 |
7.965e-03 |
0.384 |
-2.363 |
LRRN3 |
leucine rich repeat neuronal 3 |
7 |
110518297 |
AL442092 |
54674 |
7q31.1 |
Hs.3781 |
6 |
protein binding membrane integral to membrane |
|
1563743_at |
-0.335 |
3.552 |
-3.315 |
4.637e-03 |
0.335 |
-1.903 |
C1orf180 |
chromosome 1 open reading frame 180 |
1 |
-84866500 |
AK092806 |
439927 |
1p22.3 |
Hs.407054 |
2 |
|
|
37170_at |
0.410 |
3.934 |
2.954 |
9.734e-03 |
0.407 |
-2.533 |
BMP2K |
BMP2 inducible kinase |
4 |
79916555, 79916555 |
AB015331 |
55589 |
4q21.21 |
Hs.146551 |
11 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity |
|
1552301_a_at |
0.519 |
10.094 |
2.927 |
1.028e-02 |
0.417 |
-2.579 |
CORO6 |
coronin 6 |
17 |
-24965899 |
NM_032854 |
84940 |
17q11.2 |
Hs.143046 |
7 |
|
|
208818_s_at |
0.431 |
8.197 |
2.238 |
4.055e-02 |
0.570 |
-3.732 |
COMT |
catechol-O-methyltransferase |
22 |
18309262, 18318459, 18319044, 18330069 |
BC000419 |
1312 |
22q11.21 22q11.21-q11.23 |
Hs.370408 Hs.704514 Hs.713616 |
742 |
magnesium ion binding protein binding soluble fraction cytoplasm microsome cytosol plasma membrane catecholamine metabolic process integral to membrane catechol O-methyltransferase activity catechol O-methyltransferase activity transferase activity neurotransmitter catabolic process dopamine catabolic process |
Tyrosine metabolism Betalain biosynthesis Metabolic pathways |
214948_s_at |
0.432 |
6.648 |
2.680 |
1.697e-02 |
0.469 |
-3.004 |
TMF1 |
TATA element modulatory factor 1 |
3 |
-69151667 |
AL050136 |
7110 |
3p21-p12 |
Hs.267632 |
15 |
Golgi membrane DNA binding RNA polymerase II transcription factor activity transcription cofactor activity protein binding nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter membrane |
|
224735_at |
0.284 |
6.439 |
2.236 |
4.078e-02 |
0.570 |
-3.736 |
CYBASC3 |
cytochrome b, ascorbate dependent 3 |
11 |
-60872797, -60872797 |
AA683481 |
220002 |
11q12.2 |
Hs.22546 |
8 |
iron ion binding lysosome endosome transport membrane integral to membrane oxidoreductase activity electron transport chain metal ion binding |
|
237094_at |
0.661 |
2.970 |
5.046 |
1.389e-04 |
0.169 |
1.043 |
FAM19A5 |
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 |
22 |
47263951, 47350781 |
AI953086 |
25817 |
22q13.32 |
Hs.436854 Hs.632788 |
8 |
extracellular region membrane integral to membrane |
|
232051_at |
CCDC102A |
coiled-coil domain containing 102A |
16 |
-56103592 |
BC004307 |
92922 |
16q21 |
Hs.644611 |
2 |
|
|
223145_s_at |
0.599 |
8.565 |
3.759 |
1.856e-03 |
0.271 |
-1.124 |
AKIRIN2 |
akirin 2 |
6 |
-88441298 |
BC000764 |
55122 |
6q15 |
Hs.485915 |
10 |
protein binding nucleus embryonic development transcriptional repressor complex response to lipopolysaccharide positive regulation of interleukin-6 production innate immune response regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
|
228306_at |
CNIH4 |
cornichon homolog 4 (Drosophila) |
1 |
222611217 |
T87074 |
29097 |
1q42.11 |
Hs.195403 Hs.445890 |
11 |
protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane |
|
225029_at |
0.824 |
6.807 |
4.238 |
6.960e-04 |
0.211 |
-0.295 |
LOC550643 |
hypothetical LOC550643 |
X |
56772442 |
BE621082 |
550643 |
Xp11.1 |
Hs.355559 |
1 |
|
|
222222_s_at |
0.780 |
6.876 |
3.691 |
2.134e-03 |
0.276 |
-1.242 |
HOMER3 |
homer homolog 3 (Drosophila) |
19 |
-18901009, -18901009, -18901009, -18901009, -18901009 |
AC002985 |
9454 |
19p13.11 |
Hs.10326 |
16 |
protein binding cytoplasm plasma membrane protein targeting metabotropic glutamate receptor signaling pathway postsynaptic density cell junction synapse postsynaptic membrane |
|
208840_s_at |
G3BP2 |
GTPase activating protein (SH3 domain) binding protein 2 |
4 |
-76786976, -76786976 |
AU149503 |
9908 |
4q21.1 |
Hs.303676 |
15 |
nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport |
|
202179_at |
0.485 |
6.492 |
4.817 |
2.175e-04 |
0.172 |
0.675 |
BLMH |
bleomycin hydrolase |
17 |
-25599348 |
NM_000386 |
642 |
17q11.2 |
Hs.371914 |
27 |
aminopeptidase activity carboxypeptidase activity cysteine-type endopeptidase activity soluble fraction nucleus cytoplasm proteolysis peptidase activity response to toxin response to drug |
|
242274_x_at |
-0.579 |
4.133 |
-3.537 |
2.932e-03 |
0.298 |
-1.512 |
SLC25A42 |
solute carrier family 25, member 42 |
19 |
19035807 |
AI057363 |
284439 |
19p13.11 |
Hs.303669 |
3 |
binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
222576_s_at |
EIF2C1 |
eukaryotic translation initiation factor 2C, 1 |
1 |
36121396 |
AW071829 |
26523 |
1p35-p34 |
Hs.22867 |
26 |
cytoplasmic mRNA processing body nuclear-transcribed mRNA catabolic process RNA binding protein binding cytoplasm regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation regulation of transcription |
|
223063_at |
0.408 |
7.243 |
2.990 |
9.053e-03 |
0.396 |
-2.472 |
C1orf198 |
chromosome 1 open reading frame 198 |
1 |
-229039487, -229039487, -229039487 |
BC004870 |
84886 |
1q42.13-q43 |
Hs.520494 |
6 |
|
|
223165_s_at |
0.670 |
6.905 |
2.580 |
2.074e-02 |
0.497 |
-3.173 |
IP6K2 |
inositol hexakisphosphate kinase 2 |
3 |
-48705886, -48700439 |
BC004469 |
51447 |
3p21.31 |
Hs.595983 |
18 |
nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding nucleus cytoskeleton inositol trisphosphate 3-kinase activity transferase activity negative regulation of cell growth positive regulation of apoptosis phosphoinositide phosphorylation |
|
209283_at |
0.345 |
12.678 |
2.538 |
2.256e-02 |
0.501 |
-3.243 |
CRYAB |
crystallin, alpha B |
11 |
-111284559 |
AF007162 |
1410 |
11q22.3-q23.1 |
Hs.408767 |
143 |
structural constituent of eye lens soluble fraction insoluble fraction cytoplasm plasma membrane protein folding anti-apoptosis muscle contraction muscle organ development response to heat Z disc negative regulation of intracellular transport camera-type eye development contractile fiber unfolded protein binding protein homooligomerization |
|
213387_at |
ATAD2B |
ATPase family, AAA domain containing 2B |
2 |
-23825037 |
AB033066 |
54454 |
2p24.1-p23.3 |
Hs.467862 |
5 |
nucleotide binding ATP binding nucleoside-triphosphatase activity |
|
228670_at |
TEP1 |
telomerase-associated protein 1 |
14 |
-19903666 |
BF197089 |
7011 |
14q11.2 |
Hs.508835 |
19 |
nucleotide binding telomere maintenance via recombination chromosome, telomeric region telomerase activity RNA binding ATP binding soluble fraction nucleus chromosome telomerase holoenzyme complex cytoplasm nuclear matrix |
|
212202_s_at |
0.414 |
7.231 |
2.846 |
1.215e-02 |
0.426 |
-2.721 |
TMEM87A |
transmembrane protein 87A |
15 |
-40337427, -40290017 |
BG493972 |
25963 |
15q15.1 |
Hs.511138 Hs.719196 |
6 |
membrane integral to membrane |
|
223228_at |
0.559 |
7.426 |
3.333 |
4.465e-03 |
0.331 |
-1.870 |
LDOC1L |
leucine zipper, down-regulated in cancer 1-like |
22 |
-43267113 |
AL136553 |
84247 |
22q13.31 |
Hs.715637 |
6 |
|
|
203884_s_at |
0.302 |
6.039 |
3.257 |
5.227e-03 |
0.348 |
-2.005 |
RAB11FIP2 |
RAB11 family interacting protein 2 (class I) |
10 |
-119754418 |
NM_014904 |
22841 |
10q26.11 |
Hs.173656 |
20 |
protein binding endosome plasma membrane protein transport |
Endocytosis |
218076_s_at |
0.350 |
7.620 |
2.467 |
2.597e-02 |
0.518 |
-3.361 |
ARHGAP17 |
Rho GTPase activating protein 17 |
16 |
-24838212 |
NM_018054 |
55114 |
16p12.1 |
Hs.373793 |
8 |
GTPase activator activity protein binding intracellular cytoplasm tight junction signal transduction membrane SH3 domain binding cell junction |
|
238799_at |
0.306 |
3.277 |
2.527 |
2.306e-02 |
0.505 |
-3.262 |
ATP5S |
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) |
14 |
49848796, 49848796 |
BE968806 |
27109 |
14q21.3 |
Hs.438489 |
12 |
mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o) |
|
1562017_at |
LOC100130654 |
hypothetical protein LOC100130654 |
17 |
|
AK095243 |
100130654 |
17q21.2 |
Hs.636509 |
1 |
|
|
223654_s_at |
BRUNOL4 |
bruno-like 4, RNA binding protein (Drosophila) |
18 |
-33077005 |
BC004167 |
56853 |
18q12 |
Hs.435976 Hs.600908 |
12 |
nucleotide binding regulation of alternative nuclear mRNA splicing, via spliceosome translation repressor activity, nucleic acid binding nucleus cytoplasm germ cell development embryonic development BRE binding |
|
225033_at |
0.449 |
6.709 |
3.037 |
8.212e-03 |
0.387 |
-2.389 |
ST3GAL1 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
8 |
-134536272 |
AV721528 |
6482 |
8q24.22 |
Hs.374257 |
20 |
beta-galactoside alpha-2,3-sialyltransferase activity extracellular region Golgi apparatus protein amino acid glycosylation membrane integral to membrane integral to Golgi membrane |
O-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways |
202756_s_at |
0.497 |
7.856 |
3.172 |
6.230e-03 |
0.362 |
-2.154 |
GPC1 |
glypican 1 |
2 |
241023787 |
NM_002081 |
2817 |
2q35-q37 |
Hs.328232 |
29 |
extracellular region proteinaceous extracellular matrix extracellular space plasma membrane integral to plasma membrane anchored to membrane heparan sulfate proteoglycan binding |
|
236250_at |
0.389 |
5.927 |
3.697 |
2.106e-03 |
0.276 |
-1.231 |
AFG3L1 |
AFG3 ATPase family gene 3-like 1 (S. cerevisiae) |
16 |
88566488, 88566488 |
AI859065 |
172 |
16q24.3 |
Hs.534773 |
6 |
|
|
214541_s_at |
0.671 |
5.840 |
3.709 |
2.058e-03 |
0.274 |
-1.211 |
QKI |
quaking homolog, KH domain RNA binding (mouse) |
6 |
163755664, 163755664 |
AF142418 |
9444 |
6q26 6q26-q27 |
Hs.510324 Hs.593520 |
23 |
RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport |
|
223402_at |
DUSP23 |
dual specificity phosphatase 23 |
1 |
158017382 |
BC001140 |
54935 |
1q23.2 |
Hs.425801 |
7 |
protein tyrosine phosphatase activity nucleus cytoplasm cytosol protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity |
|
235549_at |
0.644 |
4.321 |
2.494 |
2.462e-02 |
0.513 |
-3.317 |
RNF144B |
ring finger protein 144B |
6 |
18495572 |
AL575512 |
255488 |
6p22.3 |
Hs.148741 |
6 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding |
|
212062_at |
0.512 |
7.052 |
2.958 |
9.660e-03 |
0.406 |
-2.527 |
ATP9A |
ATPase, class II, type 9A |
20 |
-49646720 |
AB014511 |
10079 |
20q13.2 |
Hs.719117 |
6 |
nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
|
225365_at |
0.316 |
5.561 |
2.305 |
3.566e-02 |
0.556 |
-3.625 |
ZDHHC20 |
zinc finger, DHHC-type containing 20 |
13 |
-20848507 |
BG249221 |
253832 |
13q12.11 |
Hs.564611 Hs.693749 |
4 |
zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding |
|
233328_x_at |
-0.339 |
5.249 |
-3.460 |
3.440e-03 |
0.308 |
-1.648 |
SLC17A9 |
solute carrier family 17, member 9 |
20 |
61054443 |
AL121673 |
63910 |
20q13.33 |
Hs.512686 |
7 |
transporter activity transport exocytosis membrane integral to membrane |
|
202157_s_at |
0.315 |
8.230 |
2.225 |
4.161e-02 |
0.573 |
-3.753 |
CUGBP2 |
CUG triplet repeat, RNA binding protein 2 |
10 |
11087264, 11099898, 11246998 |
U69546 |
10659 |
10p13 |
Hs.309288 |
25 |
nucleotide binding RNA binding protein binding nucleus cytoplasm mRNA processing regulation of heart contraction |
|
225996_at |
0.376 |
7.455 |
2.278 |
3.758e-02 |
0.564 |
-3.669 |
LONRF2 |
LON peptidase N-terminal domain and ring finger 2 |
2 |
-100256184 |
AV709727 |
164832 |
2q11.2 |
Hs.21380 |
4 |
ATP-dependent peptidase activity protein binding proteolysis zinc ion binding metal ion binding |
|
235103_at |
0.551 |
6.297 |
2.413 |
2.886e-02 |
0.534 |
-3.449 |
MAN2A1 |
mannosidase, alpha, class 2A, member 1 |
5 |
109053054 |
AA029155 |
4124 |
5q21-q22 |
Hs.432822 |
29 |
Golgi membrane in utero embryonic development liver development alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing mitochondrion organization vacuole organization respiratory gaseous exchange metabolic process zinc ion binding membrane integral to membrane hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding lung alveolus development |
N-Glycan biosynthesis Metabolic pathways |
228194_s_at |
SORCS1 |
sortilin-related VPS10 domain containing receptor 1 |
10 |
-108323410 |
AI675836 |
114815 |
10q23-q25 |
Hs.591915 |
8 |
protein binding protein binding neuropeptide signaling pathway neuropeptide receptor activity membrane integral to membrane |
|
223422_s_at |
1.254 |
6.120 |
3.737 |
1.940e-03 |
0.273 |
-1.162 |
ARHGAP24 |
Rho GTPase activating protein 24 |
4 |
86615307, 86918874, 87070449 |
AI743534 |
83478 |
4q21.23-q21.3 |
Hs.444229 |
14 |
angiogenesis GTPase activator activity protein binding intracellular cytoplasm cytoskeleton adherens junction focal adhesion signal transduction multicellular organismal development cell junction cell differentiation cell projection |
|
242917_at |
RASGEF1A |
RasGEF domain family, member 1A |
10 |
-43009989 |
AI884701 |
221002 |
10q11.21 |
Hs.125293 |
4 |
guanyl-nucleotide exchange factor activity intracellular regulation of small GTPase mediated signal transduction |
|
201387_s_at |
0.888 |
7.216 |
2.272 |
3.803e-02 |
0.565 |
-3.678 |
UCHL1 |
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
4 |
40953654 |
NM_004181 |
7345 |
4p14 |
Hs.518731 |
94 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity protein binding intracellular nucleus nucleolus cytoplasm cytoplasm cytosol ubiquitin-dependent protein catabolic process response to stress axon target recognition adult walking behavior peptidase activity omega peptidase activity cell proliferation protein deubiquitination ligase activity axon transport of mitochondrion axon eating behavior cell soma ubiquitin binding neuromuscular process |
Parkinson's disease |
243_g_at |
0.453 |
9.788 |
2.412 |
2.893e-02 |
0.534 |
-3.451 |
MAP4 |
microtubule-associated protein 4 |
3 |
-47989573, -47867183, -47867183 |
M64571 |
4134 |
3p21 |
Hs.517949 |
40 |
structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
203098_at |
CDYL |
chromodomain protein, Y-like |
6 |
4651391, 4721678, 4781330, 4835224 |
AL050164 |
9425 |
6p25.1 |
Hs.269092 |
8 |
chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription |
|
211036_x_at |
0.316 |
9.183 |
2.408 |
2.917e-02 |
0.535 |
-3.458 |
ANAPC5 |
anaphase promoting complex subunit 5 |
12 |
-120230432, -120230432 |
BC006301 |
51433 |
12q24.31 |
Hs.7101 |
28 |
G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
226317_at |
PPP4R2 |
protein phosphatase 4, regulatory subunit 2 |
3 |
73128808 |
AI983837 |
151987 |
3p13 |
Hs.431092 |
7 |
protein binding centrosome mRNA processing protein modification process RNA splicing |
|
235593_at |
0.906 |
3.420 |
3.402 |
3.876e-03 |
0.319 |
-1.750 |
ZEB2 |
zinc finger E-box binding homeobox 2 |
2 |
-144862052 |
AL546529 |
9839 |
2q22.3 |
Hs.34871 |
49 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent nervous system development zinc ion binding negative regulation of transcription phosphatase regulator activity sequence-specific DNA binding SMAD binding metal ion binding |
|
227394_at |
0.769 |
5.756 |
3.458 |
3.450e-03 |
0.308 |
-1.651 |
NCAM1 |
neural cell adhesion molecule 1 |
11 |
112337204, 112337204 |
W94001 |
4684 |
11q23.1 |
Hs.503878 |
120 |
protein binding extracellular region plasma membrane cell adhesion integral to membrane anchored to membrane |
Cell adhesion molecules (CAMs) Prion diseases |
206289_at |
-0.450 |
6.561 |
-2.876 |
1.142e-02 |
0.426 |
-2.669 |
HOXA4 |
homeobox A4 |
7 |
-27134650 |
NM_002141 |
3201 |
7p15-p14 |
Hs.533357 Hs.714774 |
22 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anatomical structure morphogenesis anterior/posterior pattern formation sequence-specific DNA binding embryonic skeletal system morphogenesis |
|
223852_s_at |
0.603 |
7.293 |
4.025 |
1.074e-03 |
0.227 |
-0.661 |
STK40 |
serine/threonine kinase 40 |
1 |
-36577811 |
BC005169 |
83931 |
1p34.3 |
Hs.471768 |
11 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity |
|
219390_at |
FKBP14 |
FK506 binding protein 14, 22 kDa |
7 |
-30019408 |
NM_017946 |
55033 |
7p14.3 |
Hs.571333 |
7 |
peptidyl-prolyl cis-trans isomerase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen protein folding isomerase activity |
|
226127_at |
0.321 |
7.177 |
2.253 |
3.947e-02 |
0.567 |
-3.709 |
ALKBH3 |
alkB, alkylation repair homolog 3 (E. coli) |
11 |
43858932 |
BF062547 |
221120 |
11p11.2 |
Hs.368920 |
11 |
damaged DNA binding iron ion binding nucleus nucleoplasm cytoplasm mitochondrion DNA repair response to DNA damage stimulus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding metal ion binding oxidation reduction |
|
224788_at |
ARF6 |
ADP-ribosylation factor 6 |
14 |
49429485 |
AV700721 |
382 |
14q21.3 |
Hs.525330 Hs.682124 |
86 |
nucleotide binding ruffle liver development GTPase activity protein binding GTP binding intracellular membrane fraction cytoplasm endosome Golgi apparatus plasma membrane cell cortex apoptosis cell motion cell adhesion small GTPase mediated signal transduction protein transport vesicle-mediated transport positive regulation of actin filament polymerization cortical actin cytoskeleton organization ruffle organization regulation of Rac protein signal transduction negative regulation of receptor-mediated endocytosis |
Endocytosis Fc gamma R-mediated phagocytosis |
210622_x_at |
CDK10 |
cyclin-dependent kinase 10 |
16 |
88280576 |
AF153430 |
8558 |
16q24 |
Hs.699177 |
16 |
nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation traversing start control point of mitotic cell cycle negative regulation of cell proliferation transferase activity |
|
218464_s_at |
C17orf63 |
chromosome 17 open reading frame 63 |
17 |
-24107122 |
NM_018182 |
55731 |
17q11.2 |
Hs.564533 |
4 |
|
|
203359_s_at |
MYCBP |
c-myc binding protein |
1 |
-39101222 |
AL525412 |
26292 |
1p33-p32.2 |
Hs.591506 |
12 |
transcription coactivator activity protein binding nucleus cytoplasm mitochondrion spermatogenesis regulation of transcription |
|
219024_at |
0.550 |
6.599 |
2.761 |
1.442e-02 |
0.447 |
-2.866 |
PLEKHA1 |
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
10 |
124124209, 124141832 |
NM_021622 |
59338 |
10q26.13 |
Hs.643512 |
16 |
phospholipid binding cellular_component nucleus cytoplasm plasma membrane biological_process |
|
1553367_a_at |
-0.394 |
4.957 |
-3.385 |
4.016e-03 |
0.323 |
-1.780 |
COX6B2 |
cytochrome c oxidase subunit VIb polypeptide 2 (testis) |
19 |
-60552881 |
NM_144613 |
125965 |
19q13.42 |
Hs.550544 |
5 |
cytochrome-c oxidase activity mitochondrion mitochondrial intermembrane space mitochondrial crista |
Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease |
204681_s_at |
RAPGEF5 |
Rap guanine nucleotide exchange factor (GEF) 5 |
7 |
-22124432 |
NM_012294 |
9771 |
7p15.3 |
Hs.174768 Hs.713217 |
10 |
intracellular nucleus nervous system development Rap guanyl-nucleotide exchange factor activity GTP-dependent protein binding regulation of small GTPase mediated signal transduction |
|
222658_s_at |
0.307 |
6.310 |
3.169 |
6.270e-03 |
0.363 |
-2.159 |
APTX |
aprataxin |
9 |
-32962607, -32962607, -32962607, -32962607, -32962607 |
BC001628 |
54840 |
9p13.3 |
Hs.20158 |
41 |
single strand break repair chromatin chromatin binding damaged DNA binding double-stranded DNA binding double-stranded RNA binding intracellular nucleus nucleoplasm nucleolus response to DNA damage stimulus cell death zinc ion binding phosphoglycolate phosphatase activity hydrolase activity regulation of protein stability DNA 5'-adenosine monophosphate hydrolase activity response to hydrogen peroxide metal ion binding protein N-terminus binding |
|
212978_at |
LRRC8B |
leucine rich repeat containing 8 family, member B |
1 |
89762984, 89796859 |
AU146004 |
23507 |
1p22.2 |
Hs.482017 Hs.632420 |
6 |
protein binding membrane integral to membrane |
|
206208_at |
CA4 |
carbonic anhydrase IV |
17 |
55582083 |
NM_000717 |
762 |
17q23 |
Hs.89485 |
30 |
carbonate dehydratase activity membrane fraction plasma membrane one-carbon metabolic process visual perception zinc ion binding lyase activity anchored to membrane metal ion binding response to stimulus |
Nitrogen metabolism |
242268_at |
CUGBP2 |
CUG triplet repeat, RNA binding protein 2 |
10 |
11087264, 11099898, 11246998 |
BE157991 |
10659 |
10p13 |
Hs.309288 |
25 |
nucleotide binding RNA binding protein binding nucleus cytoplasm mRNA processing regulation of heart contraction |
|
203787_at |
0.697 |
7.330 |
3.660 |
2.275e-03 |
0.279 |
-1.297 |
SSBP2 |
single-stranded DNA binding protein 2 |
5 |
-80751427 |
NM_012446 |
23635 |
5q14.1 |
Hs.102735 |
14 |
DNA binding single-stranded DNA binding protein binding nucleus cytoplasm transcription regulator activity regulation of transcription |
|
206703_at |
0.882 |
6.822 |
4.199 |
7.535e-04 |
0.211 |
-0.362 |
CHRNB1 |
cholinergic receptor, nicotinic, beta 1 (muscle) |
17 |
7289129 |
NM_000747 |
1140 |
17p13.1 |
Hs.330386 |
20 |
postsynaptic membrane organization nicotinic acetylcholine-activated cation-selective channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex cation transport muscle contraction signal transduction synaptic transmission, cholinergic neuromuscular synaptic transmission channel activity acetylcholine receptor activity cell junction behavioral response to nicotine regulation of membrane potential synapse postsynaptic membrane muscle fiber development neurological system process |
|
206263_at |
0.583 |
4.371 |
4.841 |
2.075e-04 |
0.172 |
0.713 |
FMO4 |
flavin containing monooxygenase 4 |
1 |
169550109 |
NM_002022 |
2329 |
1q23-q25 |
Hs.386502 |
11 |
monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome xenobiotic metabolic process membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction |
Drug metabolism - cytochrome P450 |
211039_at |
1.969 |
4.739 |
3.130 |
6.786e-03 |
0.368 |
-2.227 |
CHRNA1 |
cholinergic receptor, nicotinic, alpha 1 (muscle) |
2 |
-175320568 |
BC006314 |
1134 |
2q24-q32 |
Hs.434479 |
43 |
skeletal muscle contraction nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport signal transduction neuromuscular synaptic transmission neuromuscular junction development cell surface acetylcholine receptor activity integral to membrane regulation of action potential in neuron cell junction neuromuscular junction regulation of membrane potential postsynaptic membrane muscle maintenance skeletal muscle tissue growth neuromuscular process neuron maintenance |
|
217944_at |
POMGNT1 |
protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase |
1 |
-46426940, -46426940 |
NM_017739 |
55624 |
1p34.1 |
Hs.525134 |
24 |
Golgi membrane alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity microsome Golgi apparatus protein amino acid N-linked glycosylation protein amino acid O-linked glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity |
O-Mannosyl glycan biosynthesis |
230076_at |
0.222 |
3.351 |
2.144 |
4.862e-02 |
0.590 |
-3.881 |
PITPNM3 |
PITPNM family member 3 |
17 |
-6295306 |
BF063164 |
83394 |
17p13 |
Hs.183983 |
5 |
calcium ion binding intracellular transport visual perception lipid binding phosphatidylinositol transporter activity membrane integral to membrane phosphoinositide metabolic process receptor tyrosine kinase binding response to stimulus |
|
208649_s_at |
0.447 |
8.396 |
4.162 |
8.124e-04 |
0.214 |
-0.425 |
VCP |
valosin-containing protein |
9 |
-35046064 |
AF100752 |
7415 |
9p13.3 |
Hs.529782 |
97 |
nucleotide binding ATP binding nucleus nucleus nucleolus cytoplasm endoplasmic reticulum microsome cytosol double-strand break repair transport activation of caspase activity response to DNA damage stimulus lipid binding protein ubiquitination hydrolase activity ATPase activity protein domain specific binding modification-dependent protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol regulation of apoptosis establishment of protein localization |
|
218071_s_at |
0.432 |
7.148 |
4.355 |
5.481e-04 |
0.207 |
-0.095 |
MKRN2 |
makorin ring finger protein 2 |
3 |
12573593 |
NM_014160 |
23609 |
3p25 |
Hs.591666 |
5 |
molecular_function nucleic acid binding protein binding intracellular biological_process zinc ion binding metal ion binding |
|
224793_s_at |
TGFBR1 |
transforming growth factor, beta receptor 1 |
9 |
100907232, 100907232 |
AA604375 |
7046 |
9q22 |
Hs.494622 |
202 |
nucleotide binding activation of MAPKK activity magnesium ion binding in utero embryonic development kidney development protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity, type I type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding ATP binding signal transduction transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway heart development positive regulation of cell proliferation germ cell migration anterior/posterior pattern formation positive regulation of pathway-restricted SMAD protein phosphorylation integral to membrane transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation manganese ion binding collagen fibril organization positive regulation of cell growth positive regulation of survival gene product expression positive regulation of transcription SMAD binding protein heterodimerization activity thymus development neuron fate commitment embryonic cranial skeleton morphogenesis skeletal system morphogenesis artery morphogenesis cell motility transforming growth factor beta binding positive regulation of cell motion positive regulation of protein kinase B signaling cascade parathyroid gland development palate development pharyngeal system development positive regulation of SMAD protein nuclear translocation transforming growth factor beta receptor complex response to cholesterol |
MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia |
225735_at |
ANKRD50 |
ankyrin repeat domain 50 |
4 |
-125804915 |
AL110131 |
57182 |
4q28.1 |
Hs.480694 |
3 |
|
|
239660_at |
C20orf74 |
chromosome 20 open reading frame 74 |
20 |
-20321410 |
BF110518 |
57186 |
20p11.22 |
Hs.472285 |
4 |
GTPase activator activity intracellular cytoplasm regulation of small GTPase mediated signal transduction |
|
202670_at |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
15 |
64466264 |
AI571419 |
5604 |
15q22.1-q22.33 |
Hs.145442 |
171 |
nucleotide binding protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity receptor signaling protein tyrosine phosphatase activity protein binding ATP binding Golgi apparatus cytosol protein amino acid phosphorylation cell motion chemotaxis response to oxidative stress mitosis Ras protein signal transduction cell proliferation transferase activity neuron differentiation keratinocyte differentiation positive regulation of MAP kinase activity positive regulation of cell differentiation response to glucocorticoid stimulus |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation VEGF signaling pathway Focal adhesion Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
235068_at |
ZDHHC21 |
zinc finger, DHHC-type containing 21 |
9 |
-14607032 |
AI807206 |
340481 |
9p22.3 |
Hs.649522 |
4 |
zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding |
|
224149_x_at |
0.571 |
6.677 |
2.623 |
1.905e-02 |
0.489 |
-3.101 |
SLMAP |
sarcolemma associated protein |
3 |
57718213 |
AF304450 |
7871 |
3p21.2-p14.3 |
Hs.476432 |
11 |
smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding |
|
209645_s_at |
0.790 |
5.820 |
3.229 |
5.534e-03 |
0.353 |
-2.053 |
ALDH1B1 |
aldehyde dehydrogenase 1 family, member B1 |
9 |
38382701 |
NM_000692 |
219 |
9p11.1 |
Hs.436219 |
15 |
aldehyde dehydrogenase (NAD) activity mitochondrion mitochondrial matrix carbohydrate metabolic process oxidoreductase activity oxidation reduction |
Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways |
213434_at |
0.370 |
6.097 |
2.673 |
1.721e-02 |
0.471 |
-3.016 |
STX2 |
syntaxin 2 |
12 |
-129840099 |
H95263 |
2054 |
12q24.33 |
Hs.437585 |
28 |
SNARE binding cytokinesis cell separation during cytokinesis SNAP receptor activity membrane fraction soluble fraction endosome microsome plasma membrane intracellular protein transport signal transduction acrosome reaction ectoderm development organ morphogenesis integral to membrane vesicle-mediated transport basolateral plasma membrane apical plasma membrane microvillus assembly midbody epithelial cell differentiation plasma membrane fusion calcium-dependent protein binding gut morphogenesis |
SNARE interactions in vesicular transport |
205914_s_at |
GRIN1 |
glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
9 |
139153429 |
NM_007327 |
2902 |
9q34.3 |
Hs.558334 |
119 |
magnesium ion binding receptor activity N-methyl-D-aspartate selective glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity calcium channel activity calcium ion binding calmodulin binding plasma membrane integral to plasma membrane cation transport synaptic transmission synaptic vesicle visual learning postsynaptic density glycine binding glycine binding glutamate binding N-methyl-D-aspartate selective glutamate receptor complex synaptosome cell junction dendrite ionotropic glutamate receptor signaling pathway glutamate receptor binding regulation of membrane potential synapse postsynaptic membrane response to ethanol positive regulation of transcription from RNA polymerase II promoter calcium ion homeostasis regulation of excitatory postsynaptic membrane potential |
Calcium signaling pathway Neuroactive ligand-receptor interaction Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Huntington's disease |
212055_at |
C18orf10 |
chromosome 18 open reading frame 10 |
18 |
-32630031 |
BF689173 |
25941 |
18q12.2 |
Hs.695999 |
5 |
cytoplasm cytoskeleton microtubule |
|
227038_at |
SGMS2 |
sphingomyelin synthase 2 |
4 |
108965169, 109033868 |
AI963083 |
166929 |
4q25 |
Hs.595423 |
13 |
Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process sphingolipid metabolic process sphingomyelin biosynthetic process kinase activity transferase activity integral to Golgi membrane sphingomyelin synthase activity ceramide cholinephosphotransferase activity |
Sphingolipid metabolism Metabolic pathways |
212002_at |
0.287 |
7.210 |
2.853 |
1.195e-02 |
0.426 |
-2.707 |
C1orf144 |
chromosome 1 open reading frame 144 |
1 |
16566169 |
AL561657 |
26099 |
1p36.13 |
Hs.252967 |
2 |
|
|
225320_at |
0.426 |
7.973 |
2.144 |
4.855e-02 |
0.590 |
-3.880 |
CCDC109A |
coiled-coil domain containing 109A |
10 |
74121894 |
AA579630 |
90550 |
10q22.1 |
Hs.591366 |
2 |
membrane integral to membrane |
|
217728_at |
1.369 |
8.584 |
2.991 |
9.027e-03 |
0.396 |
-2.469 |
S100A6 |
S100 calcium binding protein A6 |
1 |
-151773699 |
NM_014624 |
6277 |
1q21 |
Hs.275243 |
47 |
ruffle calcium ion binding nucleus nuclear envelope cytoplasm cytoplasm cell cycle signal transduction axonogenesis growth factor activity zinc ion binding cell proliferation protein homodimerization activity positive regulation of fibroblast proliferation S100 beta binding calcium-dependent protein binding |
|
202598_at |
1.064 |
8.934 |
3.740 |
1.930e-03 |
0.273 |
-1.157 |
S100A13 |
S100 calcium binding protein A13 |
1 |
-151857899, -151857899, -151857899, -151857899, -151857899 |
NM_005979 |
6284 |
1q21 |
Hs.516505 |
24 |
calcium ion binding cellular_component cell differentiation |
|
200931_s_at |
0.573 |
10.478 |
3.086 |
7.433e-03 |
0.376 |
-2.304 |
VCL |
vinculin |
10 |
75427877 |
NM_014000 |
7414 |
10q22.2 |
Hs.643896 |
78 |
actin binding structural molecule activity cytoplasm plasma membrane cell-cell junction adherens junction focal adhesion cell motion cell adhesion actin cytoskeleton oxidoreductase activity lamellipodium assembly cell-substrate junction negative regulation of cell migration costamere protein complex apical junction assembly alpha-catenin binding |
Focal adhesion Adherens junction Leukocyte transendothelial migration Regulation of actin cytoskeleton |
1556341_s_at |
0.622 |
6.856 |
2.843 |
1.220e-02 |
0.426 |
-2.725 |
MAPK12 |
mitogen-activated protein kinase 12 |
22 |
-49033457 |
AK098058 |
6300 |
22q13.33 |
Hs.432642 |
36 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding cytoplasm mitochondrion DNA damage induced protein phosphorylation cell cycle cell cycle arrest intracellular signaling cascade Ras protein signal transduction muscle organ development transferase activity myoblast differentiation |
MAPK signaling pathway VEGF signaling pathway Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway Fc epsilon RI signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway GnRH signaling pathway Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection |
212558_at |
SPRY1 |
sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
4 |
124537405, 124540132 |
BF508662 |
10252 |
4q28.1 |
Hs.436944 |
15 |
ureteric bud development induction of an organ protein binding cytoplasm cytosol plasma membrane multicellular organismal development regulation of signal transduction lamellipodium negative regulation of MAP kinase activity |
Jak-STAT signaling pathway |
204363_at |
F3 |
coagulation factor III (thromboplastin, tissue factor) |
1 |
-94767319 |
NM_001993 |
2152 |
1p22-p21 |
Hs.62192 |
257 |
positive regulation of endothelial cell proliferation protease binding activation of plasma proteins involved in acute inflammatory response activation of blood coagulation via clotting cascade phospholipid binding extracellular space plasma membrane plasma membrane anti-apoptosis activation of caspase activity blood coagulation, extrinsic pathway positive regulation of platelet-derived growth factor receptor signaling pathway integral to membrane positive regulation of cell migration extracellular matrix intrinsic to external side of plasma membrane cell surface binding positive regulation of angiogenesis positive regulation of positive chemotaxis positive regulation of protein kinase B signaling cascade |
Complement and coagulation cascades |
232052_at |
0.468 |
6.015 |
5.408 |
6.919e-05 |
0.162 |
1.609 |
LOC440944 |
hypothetical LOC440944 |
3 |
-9405536 |
AL110136 |
440944 |
3p25.3 |
Hs.598958 Hs.652556 |
2 |
|
|
203360_s_at |
0.562 |
6.026 |
2.801 |
1.330e-02 |
0.435 |
-2.798 |
MYCBP |
c-myc binding protein |
1 |
-39101222 |
D50692 |
26292 |
1p33-p32.2 |
Hs.591506 |
12 |
transcription coactivator activity protein binding nucleus cytoplasm mitochondrion spermatogenesis regulation of transcription |
|
1553600_at |
TMIE |
transmembrane inner ear |
3 |
46717826 |
NM_147196 |
259236 |
3p21 |
Hs.185777 |
10 |
sensory perception of sound membrane integral to membrane inner ear morphogenesis |
|
212146_at |
PLEKHM2 |
pleckstrin homology domain containing, family M (with RUN domain) member 2 |
1 |
15883413 |
AB020649 |
23207 |
1p36.21 |
Hs.646775 |
3 |
cytoplasm |
|
212899_at |
CDC2L6 |
cell division cycle 2-like 6 (CDK8-like) |
6 |
-111037873 |
AB028951 |
23097 |
6q21 |
Hs.719138 |
10 |
nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity |
|
206383_s_at |
0.561 |
5.206 |
3.197 |
5.908e-03 |
0.357 |
-2.109 |
G3BP2 |
GTPase activating protein (SH3 domain) binding protein 2 |
4 |
-76786976, -76786976 |
NM_012297 |
9908 |
4q21.1 |
Hs.303676 |
15 |
nucleotide binding RNA binding protein binding intracellular cytoplasm transport cytoplasmic sequestering of NF-kappaB Ras protein signal transduction receptor signaling complex scaffold activity mRNA transport |
|
214985_at |
0.339 |
3.113 |
3.040 |
8.158e-03 |
0.387 |
-2.383 |
EXT1 |
exostoses (multiple) 1 |
8 |
-118880782 |
AF070571 |
2131 |
8q24.11-q24.13 |
Hs.492618 |
53 |
Golgi membrane skeletal system development ossification protein binding endoplasmic reticulum Golgi apparatus glycosaminoglycan biosynthetic process signal transduction gastrulation endoderm development mesoderm development heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process membrane integral to membrane integral to endoplasmic reticulum membrane heparan sulfate N-acetylglucosaminyltransferase activity protein homodimerization activity protein heterodimerization activity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
Heparan sulfate biosynthesis Metabolic pathways |
213271_s_at |
DOPEY1 |
dopey family member 1 |
6 |
83834103 |
AB029040 |
23033 |
6q15 |
Hs.520246 Hs.708998 |
6 |
protein transport |
|
212188_at |
0.990 |
7.397 |
3.822 |
1.629e-03 |
0.260 |
-1.013 |
KCTD12 |
potassium channel tetramerisation domain containing 12 |
13 |
-76352304 |
AA551075 |
115207 |
13q22.3 |
Hs.644125 |
14 |
voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane |
|
1555575_a_at |
0.241 |
9.171 |
2.876 |
1.142e-02 |
0.426 |
-2.669 |
KDELR1 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
19 |
-53577638 |
BC008958 |
10945 |
19q13.3 |
Hs.515515 |
14 |
receptor activity KDEL sequence binding protein binding membrane fraction endoplasmic reticulum ER-Golgi intermediate compartment protein retention in ER lumen intracellular protein transport membrane integral to membrane vesicle-mediated transport |
Vibrio cholerae infection |
1563471_at |
KIAA1632 |
KIAA1632 |
18 |
-41681571 |
AL833448 |
57724 |
18q12.3-q21.1 |
Hs.514843 |
8 |
|
|
225243_s_at |
0.478 |
8.469 |
2.285 |
3.706e-02 |
0.562 |
-3.657 |
SLMAP |
sarcolemma associated protein |
3 |
57718213 |
AB046821 |
7871 |
3p21.2-p14.3 |
Hs.476432 |
11 |
smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding |
|
242750_at |
MMAA |
methylmalonic aciduria (cobalamin deficiency) cblA type |
4 |
146759989 |
AA678047 |
166785 |
4q31.21 |
Hs.452864 |
10 |
nucleotide binding ATP binding mitochondrion nucleoside-triphosphatase activity |
|
233169_at |
ZNF350 |
zinc finger protein 350 |
19 |
-57159404 |
AU145915 |
59348 |
19q13.41 |
Hs.407694 |
23 |
DNA binding protein binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding nuclear matrix negative regulation of transcription transcription repressor activity transcriptional repressor complex metal ion binding |
|
222653_at |
0.374 |
6.777 |
3.098 |
7.245e-03 |
0.375 |
-2.282 |
PNPO |
pyridoxamine 5'-phosphate oxidase |
17 |
43373887 |
AA005137 |
55163 |
17q21.32 |
Hs.631742 |
13 |
pyridoxamine-phosphate oxidase activity pyridoxine biosynthetic process FMN binding oxidoreductase activity, acting on the CH-NH2 group of donors oxidation reduction |
Vitamin B6 metabolism Metabolic pathways |
227886_at |
CTSD |
cathepsin D |
11 |
-1730560 |
AU147615 |
1509 |
11p15.5 |
Hs.121575 Hs.654447 |
140 |
autophagic vacuole formation aspartic-type endopeptidase activity extracellular region mitochondrion lysosome proteolysis peptidase activity melanosome |
Lysosome |
1553961_s_at |
0.719 |
6.769 |
4.013 |
1.100e-03 |
0.227 |
-0.681 |
SNX21 |
sorting nexin family member 21 |
20 |
43895876 |
CA447177 |
90203 |
20q13.12 |
Hs.472854 |
8 |
protein binding cell communication protein transport phosphoinositide binding |
|
225601_at |
0.891 |
5.667 |
3.912 |
1.354e-03 |
0.245 |
-0.856 |
HMGB3 |
high-mobility group box 3 |
X |
149902420 |
AI806853 |
3149 |
Xq28 |
Hs.19114 |
11 |
nucleus chromosome multicellular organismal development DNA bending activity negative regulation of B cell differentiation negative regulation of myeloid cell differentiation |
|
228962_at |
PDE4D |
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) |
5 |
-58300622, -58300622 |
BF507941 |
5144 |
5q12 |
Hs.117545 |
89 |
3',5'-cyclic-AMP phosphodiesterase activity soluble fraction insoluble fraction cytoplasm centrosome cytoskeleton signal transduction membrane hydrolase activity metal ion binding |
Purine metabolism |
210749_x_at |
0.742 |
7.205 |
3.400 |
3.890e-03 |
0.319 |
-1.753 |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
6 |
30959839, 30960305, 30964443, 2300465, 2300931, 2305069, 2098794, 2099260, 2103398 |
L11315 |
780 |
6p21.3 |
Hs.631988 |
60 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding extracellular region integral to plasma membrane protein amino acid phosphorylation cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity |
|
1554549_a_at |
0.570 |
3.234 |
2.828 |
1.257e-02 |
0.429 |
-2.750 |
WDR20 |
WD repeat domain 20 |
14 |
101675964, 101675964, 101675964 |
BC030654 |
91833 |
14q32.31 |
Hs.36859 |
7 |
|
|
221606_s_at |
NSBP1 |
nucleosomal binding protein 1 |
X |
-80255855 |
BC005342 |
79366 |
Xq13.3 |
Hs.282204 |
7 |
chromatin DNA binding chromatin binding nucleus nucleoplasm nucleolus regulation of transcription from RNA polymerase I promoter transcription activator activity |
|
210753_s_at |
-0.332 |
4.633 |
-2.136 |
4.931e-02 |
0.590 |
-3.892 |
EPHB1 |
EPH receptor B1 |
3 |
135996949 |
AF037334 |
2047 |
3q21-q23 |
Hs.116092 |
41 |
nucleotide binding receptor activity ephrin receptor activity protein binding ATP binding plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway nervous system development transferase activity |
Axon guidance |
1564254_at |
-0.197 |
5.437 |
-2.371 |
3.135e-02 |
0.543 |
-3.518 |
KY |
kyphoscoliosis peptidase |
3 |
-135801454 |
AK090526 |
339855 |
3q22.2 |
Hs.146730 |
4 |
cytoplasm cytoskeleton peptidase activity |
|
213868_s_at |
DHRS7 |
dehydrogenase/reductase (SDR family) member 7 |
14 |
-59681251 |
AW243128 |
51635 |
14q23.1 |
Hs.59719 |
7 |
binding oxidoreductase activity oxidation reduction |
|
203567_s_at |
0.613 |
6.397 |
3.238 |
5.432e-03 |
0.352 |
-2.037 |
TRIM38 |
tripartite motif-containing 38 |
6 |
26071049 |
AU157590 |
10475 |
6p21.3 |
Hs.584851 |
7 |
signal transducer activity protein binding cellular_component intracellular zinc ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding |
|
226180_at |
0.646 |
6.777 |
3.001 |
8.840e-03 |
0.394 |
-2.451 |
WDR36 |
WD repeat domain 36 |
5 |
110455768 |
BF439595 |
134430 |
5q22.1 |
Hs.533237 |
19 |
molecular_function cellular_component rRNA processing visual perception small-subunit processome response to stimulus |
|
222396_at |
0.700 |
8.041 |
2.146 |
4.841e-02 |
0.589 |
-3.877 |
HN1 |
hematological and neurological expressed 1 |
17 |
-70642938, -70642938 |
AF060925 |
51155 |
17q25.1 |
Hs.532803 Hs.713826 |
9 |
nucleus |
|
226996_at |
LCLAT1 |
lysocardiolipin acyltransferase 1 |
2 |
30523626, 30523640 |
AV717041 |
253558 |
2p23.1 |
Hs.468048 Hs.662770 |
8 |
1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum multicellular organismal development metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity |
Tyrosine metabolism Phenylalanine metabolism Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism 1- and 2-Methylnaphthalene degradation Benzoate degradation via CoA ligation Limonene and pinene degradation Metabolic pathways |
209155_s_at |
NT5C2 |
5'-nucleotidase, cytosolic II |
10 |
-104835929 |
BC001595 |
22978 |
10q24.32-q24.33 |
Hs.97439 |
12 |
nucleotide binding magnesium ion binding protein binding cytoplasm cytosol 5'-nucleotidase activity 5'-nucleotidase activity nucleotide metabolic process hydrolase activity |
Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways |
235440_at |
0.356 |
4.024 |
3.073 |
7.634e-03 |
0.378 |
-2.327 |
SPTY2D1 |
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) |
11 |
-18584523 |
BE780878 |
144108 |
11p15.1 |
Hs.268668 Hs.719399 |
2 |
|
|
202642_s_at |
0.417 |
5.955 |
2.572 |
2.106e-02 |
0.497 |
-3.186 |
TRRAP |
transformation/transcription domain-associated protein |
7 |
98314048 |
NM_003496 |
8295 |
7q21.2-q22.1 |
Hs.203952 Hs.706926 |
40 |
PCAF complex transcription cofactor activity protein binding nucleus chromatin modification histone deubiquitination phosphotransferase activity, alcohol group as acceptor STAGA complex transcription factor TFTC complex NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation regulation of transcription |
|
211071_s_at |
1.069 |
8.059 |
3.091 |
7.347e-03 |
0.376 |
-2.294 |
MLLT11 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
1 |
149298774 |
BC006471 |
10962 |
1q21 |
Hs.75823 |
9 |
molecular_function cellular_component |
|
225814_at |
XRN1 |
5'-3' exoribonuclease 1 |
3 |
-143508138 |
BG534738 |
54464 |
3q23 |
Hs.435103 |
12 |
DNA binding RNA binding protein binding intracellular cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5'-3' exonuclease activity hydrolase activity |
RNA degradation |
202204_s_at |
AMFR |
autocrine motility factor receptor |
16 |
-54952864 |
AF124145 |
267 |
16q21 |
Hs.295137 |
33 |
protein polyubiquitination integral to membrane of membrane fraction ubiquitin-protein ligase activity ubiquitin-protein ligase activity receptor activity receptor activity protein binding endoplasmic reticulum ubiquitin-dependent protein catabolic process cell motion signal transduction zinc ion binding membrane integral to membrane integral to membrane ligase activity integral to endoplasmic reticulum membrane ER-associated protein catabolic process ER-associated protein catabolic process endoplasmic reticulum unfolded protein response metal ion binding protein oligomerization |
|
225978_at |
0.593 |
5.474 |
2.369 |
3.149e-02 |
0.543 |
-3.522 |
RIMKLB |
ribosomal modification protein rimK-like family member B |
12 |
8741784 |
AW409794 |
57494 |
12p13.31 |
Hs.504670 |
4 |
nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding |
|
221649_s_at |
0.346 |
6.484 |
3.988 |
1.159e-03 |
0.231 |
-0.725 |
PPAN |
peter pan homolog (Drosophila) |
19 |
10077964 |
BC000535 |
56342 |
19p13 |
Hs.14468 |
15 |
protein binding nucleus nucleolus RNA splicing |
|
205499_at |
0.680 |
4.423 |
5.119 |
1.206e-04 |
0.162 |
1.159 |
SRPX2 |
sushi-repeat-containing protein, X-linked 2 |
X |
99785818 |
NM_014467 |
27286 |
Xq21.33-q23 |
Hs.306339 |
13 |
extracellular region |
|
1557349_at |
RERE |
arginine-glutamic acid dipeptide (RE) repeats |
1 |
-8335050, -8335050 |
AK096094 |
473 |
1p36.2-p36.1 |
Hs.463041 |
17 |
histone deacetylase complex transcription factor activity nucleus chromatin remodeling regulation of transcription, DNA-dependent NLS-bearing substrate import into nucleus multicellular organismal development poly-glutamine tract binding zinc ion binding sequence-specific DNA binding metal ion binding |
|
215942_s_at |
GTSE1 |
G-2 and S-phase expressed 1 |
22 |
45071301 |
BF973178 |
51512 |
22q13.2-q13.3 |
Hs.386189 |
18 |
G2 phase of mitotic cell cycle molecular_function cytoplasm cytoplasmic microtubule DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest microtubule-based process |
p53 signaling pathway |
215559_at |
ABCC6 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
16 |
-16222544, -16150922 |
AI074459 |
368 |
16p13.1 |
Hs.442182 |
70 |
nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus |
ABC transporters |
225160_x_at |
MDM2 |
Mdm2 p53 binding protein homolog (mouse) |
12 |
67488237, 67489063 |
AI952357 |
4193 |
12q14.3-q15 |
Hs.484551 |
555 |
negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding |
Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia |
202055_at |
KPNA1 |
karyopherin alpha 1 (importin alpha 5) |
3 |
-123623437 |
AA652173 |
3836 |
3q21 |
Hs.161008 |
92 |
regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
217830_s_at |
NSFL1C |
NSFL1 (p97) cofactor (p47) |
20 |
-1370810 |
AL109658 |
55968 |
20p13 |
Hs.12865 |
20 |
protein binding nucleus Golgi apparatus Golgi stack lipid binding |
|
223547_at |
JKAMP |
JNK1/MAPK8-associated membrane protein |
14 |
59020913 |
AL038769 |
51528 |
14q23.1 |
Hs.446850 |
12 |
plasma membrane integral to membrane |
|
225164_s_at |
0.325 |
5.534 |
2.844 |
1.217e-02 |
0.426 |
-2.723 |
EIF2AK4 |
eukaryotic translation initiation factor 2 alpha kinase 4 |
15 |
38013638 |
AB037759 |
440275 |
15q15.1 |
Hs.656673 |
10 |
nucleotide binding eukaryotic translation initiation factor 2alpha kinase activity aminoacyl-tRNA ligase activity protein binding ATP binding intracellular cytoplasm tRNA aminoacylation for protein translation regulation of translational initiation protein amino acid phosphorylation transferase activity cytosolic ribosome |
|
210211_s_at |
0.355 |
11.097 |
2.519 |
2.344e-02 |
0.507 |
-3.275 |
HSP90AA1 |
heat shock protein 90kDa alpha (cytosolic), class A member 1 |
14 |
-101616827, -101616827 |
AF028832 |
3320 |
14q32.33 |
Hs.525600 Hs.700831 |
275 |
nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly |
Antigen processing and presentation Pathways in cancer Prostate cancer |
244462_at |
0.440 |
3.408 |
3.041 |
8.149e-03 |
0.387 |
-2.382 |
ZNF224 |
zinc finger protein 224 |
19 |
49290336 |
AA811983 |
7767 |
19q13.2 |
Hs.585869 |
10 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
213571_s_at |
EIF4E2 |
eukaryotic translation initiation factor 4E family member 2 |
2 |
233123600 |
BF516289 |
9470 |
2q37.1 |
Hs.292026 Hs.700929 |
15 |
RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation |
mTOR signaling pathway Insulin signaling pathway |
230285_at |
SVIP |
small VCP/p97-interacting protein |
11 |
-22800173 |
BF447829 |
258010 |
11p14.2 |
Hs.349096 |
4 |
endoplasmic reticulum Golgi apparatus plasma membrane |
|
1559315_s_at |
-0.233 |
2.890 |
-2.494 |
2.462e-02 |
0.513 |
-3.317 |
LOC144481 |
hypothetical protein LOC144481 |
12 |
|
AK054607 |
144481 |
12q22 |
Hs.602278 |
1 |
|
|
232643_at |
-0.251 |
5.610 |
-2.488 |
2.491e-02 |
0.513 |
-3.326 |
POLR2F |
polymerase (RNA) II (DNA directed) polypeptide F |
22 |
36679619 |
AK026327 |
5435 |
22q13.1 |
Hs.436578 |
87 |
nuclear mRNA splicing, via spliceosome DNA binding DNA-directed RNA polymerase activity nucleus nucleoplasm nucleolus transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter RNA polymerase complex |
Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase Huntington's disease |
1559061_at |
LOC253962 |
hypothetical protein LOC253962 |
17 |
|
BC041476 |
253962 |
17q21.33 |
Hs.558704 |
1 |
|
|
201122_x_at |
0.738 |
9.062 |
3.703 |
2.080e-03 |
0.275 |
-1.221 |
EIF5A |
eukaryotic translation initiation factor 5A |
17 |
7151041, 7151579, 7152011, 7152417 |
BC000751 |
1984 |
17p13-p12 |
Hs.534314 |
52 |
RNA binding translation initiation factor activity translation elongation factor activity nucleus annulate lamellae nuclear pore cytoplasm endoplasmic reticulum cytosol mRNA export from nucleus translation translational frameshifting protein export from nucleus nucleocytoplasmic transport nucleocytoplasmic transport induction of apoptosis cell proliferation peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine protein transport membrane U6 snRNA binding viral genome replication ribosome binding positive regulation of translational elongation positive regulation of translational termination positive regulation of translational initiation protein N-terminus binding intracellular protein transmembrane transport |
|
200945_s_at |
SEC31A |
SEC31 homolog A (S. cerevisiae) |
4 |
-83958837 |
NM_014933 |
22872 |
4q21.22 |
Hs.370024 |
20 |
cytoplasm endoplasmic reticulum ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport protein transport membrane membrane organization vesicle-mediated transport COPII vesicle coat cytoplasmic vesicle calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion |
|
220552_at |
-0.317 |
2.509 |
-3.726 |
1.985e-03 |
0.273 |
-1.181 |
TRPC5 |
transient receptor potential cation channel, subfamily C, member 5 |
X |
-110904197 |
NM_012471 |
7224 |
Xq23 |
Hs.657709 |
27 |
ion channel activity calcium ion binding protein binding integral to plasma membrane ion transport calcium ion transport nervous system development store-operated calcium channel activity membrane |
|
205591_at |
OLFM1 |
olfactomedin 1 |
9 |
137106909, 137106923 |
NM_006334 |
10439 |
9q34.3 |
Hs.522484 |
9 |
protein binding endoplasmic reticulum endoplasmic reticulum lumen multicellular organismal development nervous system development membrane |
|
223355_at |
0.320 |
4.114 |
3.546 |
2.878e-03 |
0.297 |
-1.497 |
ALG1 |
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae) |
16 |
5061810 |
BC004402 |
56052 |
16p13.3 |
Hs.592086 |
9 |
chitobiosyldiphosphodolichol beta-mannosyltransferase activity endoplasmic reticulum protein amino acid glycosylation biosynthetic process lipopolysaccharide biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups |
N-Glycan biosynthesis Metabolic pathways |
226648_at |
0.448 |
6.811 |
2.981 |
9.221e-03 |
0.400 |
-2.487 |
HIF1AN |
hypoxia inducible factor 1, alpha subunit inhibitor |
10 |
102285630 |
AI769745 |
55662 |
10q24 |
Hs.500788 |
30 |
peptide-aspartate beta-dioxygenase activity iron ion binding protein binding nucleus oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction |
|
201765_s_at |
0.354 |
7.537 |
3.913 |
1.350e-03 |
0.245 |
-0.854 |
HEXA |
hexosaminidase A (alpha polypeptide) |
15 |
-70422831 |
AL523158 |
3073 |
15q23-q24 |
Hs.604479 Hs.709495 |
93 |
skeletal system development hydrolase activity, hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity protein binding lysosome carbohydrate metabolic process ganglioside catabolic process lysosome organization sensory perception of sound locomotory behavior adult walking behavior metabolic process membrane lipid storage sexual reproduction glycosaminoglycan metabolic process myelination cation binding protein heterodimerization activity neuromuscular process controlling posture neuromuscular process controlling balance |
Other glycan degradation Amino sugar and nucleotide sugar metabolism Glycosaminoglycan degradation Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways Lysosome |
1556667_at |
0.789 |
5.469 |
2.229 |
4.128e-02 |
0.571 |
-3.746 |
LOC348751 |
hypothetical protein LOC348751 |
2 |
|
BC039445 |
348751 |
2q33.1 |
Hs.471039 |
1 |
|
|
209824_s_at |
ARNTL |
aryl hydrocarbon receptor nuclear translocator-like |
11 |
13255900 |
AB000812 |
406 |
11p15 |
Hs.65734 |
37 |
transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction circadian rhythm aryl hydrocarbon receptor binding positive regulation of transcription from RNA polymerase II promoter Hsp90 protein binding |
Circadian rhythm - mammal |
216199_s_at |
MAP3K4 |
mitogen-activated protein kinase kinase kinase 4 |
6 |
161332811 |
AL109942 |
4216 |
6q26 |
Hs.390428 |
20 |
nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding response to stress JNK cascade transferase activity |
MAPK signaling pathway GnRH signaling pathway |
218024_at |
-0.374 |
10.668 |
-2.178 |
4.551e-02 |
0.581 |
-3.827 |
BRP44L |
brain protein 44-like |
6 |
-166698399 |
NM_016098 |
51660 |
6q27 |
Hs.172755 |
7 |
molecular_function cellular_component mitochondrion biological_process |
|
1553715_s_at |
C16orf14 |
chromosome 16 open reading frame 14 |
16 |
631849 |
NM_032371 |
84331 |
16p13.3 |
Hs.417710 |
5 |
protein binding |
|
231132_at |
-0.354 |
5.284 |
-3.508 |
3.112e-03 |
0.303 |
-1.563 |
LOC348120 |
hypothetical protein LOC348120 |
15 |
|
AW002496 |
348120 |
15q11.2 |
Hs.116287 |
1 |
|
|
217841_s_at |
PPME1 |
protein phosphatase methylesterase 1 |
11 |
73560015 |
NM_016147 |
51400 |
11q13.4 |
Hs.503251 |
10 |
carboxylesterase activity phosphoprotein phosphatase inhibitor activity protein amino acid demethylation protein phosphatase type 2A regulator activity hydrolase activity protein phosphatase 2A binding protein C-terminal methylesterase activity |
Tropane, piperidine and pyridine alkaloid biosynthesis |
225433_at |
GTF2A1 |
general transcription factor IIA, 1, 19/37kDa |
14 |
-80716146, -80716146 |
AU144104 |
2957 |
14q31.1 |
Hs.592334 Hs.593630 |
45 |
DNA binding transcription coactivator activity nucleus nucleoplasm transcription factor TFIIA complex nucleolus cytoplasm transcription initiation from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter RNA elongation from RNA polymerase II promoter transcription factor binding general RNA polymerase II transcription factor activity TATA-binding protein binding general transcription from RNA polymerase II promoter regulation of transcription protein heterodimerization activity |
Basal transcription factors |
213245_at |
-0.569 |
5.967 |
-2.919 |
1.047e-02 |
0.418 |
-2.595 |
ADCY1 |
adenylate cyclase 1 (brain) |
7 |
45580649 |
AL120173 |
107 |
7p13-p12 |
Hs.192215 |
24 |
nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane |
Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis |
218152_at |
HMG20A |
high-mobility group 20A |
15 |
75500297 |
NM_018200 |
10363 |
15q24 |
Hs.69594 |
9 |
transcription factor activity protein binding nucleus nucleolus regulation of transcription, DNA-dependent chromatin modification |
|
222156_x_at |
0.392 |
6.792 |
2.246 |
3.995e-02 |
0.568 |
-3.719 |
CCPG1 |
cell cycle progression 1 |
15 |
-53434729, -53434729 |
AK022459 |
9236 |
15q21.1 |
Hs.285051 |
5 |
cell cycle membrane integral to membrane |
|
201935_s_at |
EIF4G3 |
eukaryotic translation initiation factor 4 gamma, 3 |
1 |
-21005560 |
AI768122 |
8672 |
1p36.12 |
Hs.467084 |
19 |
RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms |
|
1553956_at |
ALS2CR4 |
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4 |
2 |
-202193151, -202193151 |
BG194770 |
65062 |
|
Hs.12319 |
5 |
membrane integral to membrane |
|
1552418_at |
TTLL10 |
tubulin tyrosine ligase-like family, member 10 |
1 |
1099148, 1104939 |
NM_153254 |
254173 |
1p36.33 |
Hs.454835 |
4 |
tubulin-tyrosine ligase activity cytoplasm cytoskeleton microtubule protein modification process ligase activity protein polyglycylation protein-glycine ligase activity |
|
219981_x_at |
ZNF587 |
zinc finger protein 587 |
19 |
63053080 |
NM_017961 |
84914 |
19q13.43 |
Hs.642598 Hs.715493 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
243738_at |
NMNAT3 |
nicotinamide nucleotide adenylyltransferase 3 |
3 |
-140761722 |
AW172570 |
349565 |
3q23 |
Hs.208673 |
6 |
nucleotide binding magnesium ion binding nicotinamide-nucleotide adenylyltransferase activity nicotinate-nucleotide adenylyltransferase activity ATP binding mitochondrion biosynthetic process NAD biosynthetic process transferase activity nucleotidyltransferase activity pyridine nucleotide biosynthetic process |
Nicotinate and nicotinamide metabolism Metabolic pathways |
212271_at |
0.354 |
7.929 |
2.683 |
1.688e-02 |
0.467 |
-2.999 |
MAPK1 |
mitogen-activated protein kinase 1 |
22 |
-20453318, -20443946 |
AA195999 |
5594 |
22q11.2 22q11.21 |
Hs.431850 |
822 |
MAPKKK cascade nucleotide binding phosphotyrosine binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol cytoskeleton protein amino acid phosphorylation induction of apoptosis chemotaxis response to DNA damage stimulus cell cycle Ras protein signal transduction synaptic transmission organ morphogenesis transferase activity MAP kinase 2 activity cytosine metabolic process lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to exogenous dsRNA interspecies interaction between organisms negative regulation of cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation TGF-beta signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Type II diabetes mellitus Alzheimer's disease Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
219440_at |
RAI2 |
retinoic acid induced 2 |
X |
-17728089 |
NM_021785 |
10742 |
Xp22 |
Hs.446680 |
8 |
molecular_function cellular_component embryonic development |
|
213581_at |
0.857 |
5.606 |
4.051 |
1.019e-03 |
0.225 |
-0.616 |
PDCD2 |
programmed cell death 2 |
6 |
-170732759, -170728374 |
BF446180 |
5134 |
6q27 |
Hs.367900 |
14 |
DNA binding protein binding nucleus cytoplasm apoptosis zinc ion binding metal ion binding |
|
202778_s_at |
ZMYM2 |
zinc finger, MYM-type 2 |
13 |
19430809 |
NM_003453 |
7750 |
13q11-q12 |
Hs.644041 |
29 |
protein binding cellular_component nucleus biological_process zinc ion binding PML body ubiquitin conjugating enzyme binding regulation of transcription metal ion binding |
|
212248_at |
MTDH |
metadherin |
8 |
98725582 |
AI886796 |
92140 |
8q22.1 |
Hs.377155 |
23 |
negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity |
|
218527_at |
0.202 |
6.301 |
2.197 |
4.390e-02 |
0.579 |
-3.797 |
APTX |
aprataxin |
9 |
-32962607, -32962607, -32962607, -32962607, -32962607 |
NM_017692 |
54840 |
9p13.3 |
Hs.20158 |
41 |
single strand break repair chromatin chromatin binding damaged DNA binding double-stranded DNA binding double-stranded RNA binding intracellular nucleus nucleoplasm nucleolus response to DNA damage stimulus cell death zinc ion binding phosphoglycolate phosphatase activity hydrolase activity regulation of protein stability DNA 5'-adenosine monophosphate hydrolase activity response to hydrogen peroxide metal ion binding protein N-terminus binding |
|
209448_at |
0.529 |
6.969 |
2.723 |
1.557e-02 |
0.459 |
-2.931 |
HTATIP2 |
HIV-1 Tat interactive protein 2, 30kDa |
11 |
20341806, 20341822, 20341864, 20341978, 20342262 |
BC002439 |
10553 |
11p15.1 |
Hs.90753 |
31 |
RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction |
|
221903_s_at |
0.952 |
6.645 |
3.030 |
8.337e-03 |
0.387 |
-2.402 |
CYLD |
cylindromatosis (turban tumor syndrome) |
16 |
49333461, 49333529 |
BE046443 |
1540 |
16q12.1 |
Hs.578973 |
54 |
structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm |
RIG-I-like receptor signaling pathway |
226822_at |
0.444 |
5.658 |
2.857 |
1.186e-02 |
0.426 |
-2.701 |
STOX2 |
storkhead box 2 |
4 |
185063502 |
AL512713 |
56977 |
4q35.1 |
Hs.21958 Hs.696657 |
3 |
|
|
200918_s_at |
SRPR |
signal recognition particle receptor (docking protein) |
11 |
-125638043 |
NM_003139 |
6734 |
11q24.3 |
Hs.368376 |
7 |
nucleotide binding GTPase activity receptor activity signal recognition particle binding protein binding GTP binding endoplasmic reticulum signal recognition particle receptor complex SRP-dependent cotranslational protein targeting to membrane intracellular protein transport membrane integral to membrane |
Protein export |
227334_at |
0.631 |
9.327 |
2.252 |
3.953e-02 |
0.568 |
-3.710 |
USP54 |
ubiquitin specific peptidase 54 |
10 |
-74927301 |
AW242125 |
159195 |
10q22.2 |
Hs.657355 |
6 |
ubiquitin thiolesterase activity protein binding ubiquitin-dependent protein catabolic process |
|
222800_at |
-0.244 |
5.112 |
-3.020 |
8.514e-03 |
0.389 |
-2.419 |
TRNAU1AP |
tRNA selenocysteine 1 associated protein 1 |
1 |
28752115 |
BC000680 |
54952 |
1p35.3 |
Hs.533626 |
5 |
nucleotide binding selenocysteine incorporation RNA binding nucleus cytoplasm translation |
|
228871_at |
-0.275 |
4.140 |
-3.384 |
4.017e-03 |
0.323 |
-1.780 |
ALG14 |
asparagine-linked glycosylation 14 homolog (S. cerevisiae) |
1 |
-95220866 |
AI652839 |
199857 |
1p21.3 |
Hs.408927 |
5 |
endoplasmic reticulum membrane integral to membrane |
N-Glycan biosynthesis Metabolic pathways |
226723_at |
CCDC23 |
coiled-coil domain containing 23 |
1 |
-43045309 |
AI581511 |
374969 |
1p34.2 |
Hs.113919 |
4 |
|
|
1554600_s_at |
0.477 |
7.290 |
3.564 |
2.775e-03 |
0.292 |
-1.466 |
LMNA |
lamin A/C |
1 |
154351084, 154351084 |
BC033088 |
4000 |
1q21.2-q21.3 |
Hs.594444 |
279 |
structural molecule activity protein binding nucleus cytoplasm intermediate filament plasma membrane |
Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
223316_at |
0.677 |
7.140 |
3.144 |
6.588e-03 |
0.366 |
-2.201 |
CCDC3 |
coiled-coil domain containing 3 |
10 |
-12978630 |
AL136562 |
83643 |
10p13 |
Hs.498720 |
8 |
endoplasmic reticulum |
|
223206_s_at |
0.613 |
4.955 |
3.742 |
1.919e-03 |
0.273 |
-1.152 |
NMRAL1 |
NmrA-like family domain containing 1 |
16 |
-4451695 |
BC002927 |
57407 |
16p13.3 |
Hs.288969 |
8 |
binding regulation of nitrogen utilization oxidoreductase activity transcription repressor activity oxidation reduction |
|
207233_s_at |
MITF |
microphthalmia-associated transcription factor |
3 |
69871322, 69895651, 69998131, 70010945, 70068442 |
NM_000248 |
4286 |
3p14.2-p14.1 |
Hs.166017 Hs.618266 |
93 |
DNA binding nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity transcription activator activity melanocyte differentiation |
Melanogenesis Pathways in cancer Melanoma |
1554352_s_at |
0.257 |
5.320 |
2.283 |
3.720e-02 |
0.562 |
-3.660 |
DENND4A |
DENN/MADD domain containing 4A |
15 |
-63740012 |
BC041706 |
10260 |
15q22.31 |
Hs.654567 |
8 |
DNA binding protein binding nucleus regulation of transcription, DNA-dependent |
|
224843_at |
0.291 |
4.779 |
2.299 |
3.607e-02 |
0.558 |
-3.635 |
SLAIN2 |
SLAIN motif family, member 2 |
4 |
48038369 |
AB040891 |
57606 |
4p11 |
Hs.479677 |
5 |
|
|
1553146_at |
-0.301 |
4.228 |
-2.796 |
1.344e-02 |
0.437 |
-2.806 |
C3orf30 |
chromosome 3 open reading frame 30 |
3 |
120347686 |
NM_152539 |
152405 |
3q13.32 |
Hs.632574 |
1 |
|
|
213988_s_at |
0.408 |
5.980 |
2.428 |
2.806e-02 |
0.529 |
-3.426 |
SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
X |
23711195 |
BE971383 |
6303 |
Xp22.1 |
Hs.28491 |
46 |
diamine N-acetyltransferase activity protein binding intracellular cytoplasm metabolic process acyltransferase activity transferase activity |
Arginine and proline metabolism Metabolic pathways |
202780_at |
1.282 |
7.181 |
2.607 |
1.964e-02 |
0.491 |
-3.127 |
OXCT1 |
3-oxoacid CoA transferase 1 |
5 |
-41765923 |
NM_000436 |
5019 |
5p13.1 |
Hs.278277 |
15 |
mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix metabolic process 3-oxoacid CoA-transferase activity 3-oxoacid CoA-transferase activity transferase activity protein homodimerization activity ketone body catabolic process |
Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism |
223429_x_at |
0.255 |
6.937 |
2.336 |
3.359e-02 |
0.552 |
-3.576 |
ISY1 |
ISY1 splicing factor homolog (S. cerevisiae) |
3 |
-130330924 |
BC004122 |
57461 |
3q21.3 |
Hs.512661 |
7 |
nucleus spliceosomal complex nucleolus cytoplasm mRNA processing RNA splicing |
|
225010_at |
CCDC6 |
coiled-coil domain containing 6 |
10 |
-61218526 |
AK024913 |
8030 |
10q21 |
Hs.591360 |
20 |
structural constituent of cytoskeleton protein binding cellular_component cytoplasm cytoskeleton biological_process SH3 domain binding |
Pathways in cancer Thyroid cancer |
235867_at |
GSTM3 |
glutathione S-transferase mu 3 (brain) |
1 |
-110078076 |
AI459140 |
2947 |
1p13.3 |
Hs.2006 |
96 |
glutathione transferase activity cytoplasm establishment of blood-nerve barrier metabolic process transferase activity identical protein binding response to estrogen stimulus |
Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 |
234698_at |
-0.322 |
4.887 |
-3.235 |
5.465e-03 |
0.352 |
-2.042 |
N6AMT1 |
N-6 adenine-specific DNA methyltransferase 1 (putative) |
21 |
-29166383 |
AK021678 |
29104 |
21q21.3 |
Hs.163846 |
6 |
nucleic acid binding protein binding protein methyltransferase activity transferase activity positive regulation of cell growth methylation protein complex |
|
203285_s_at |
0.516 |
4.425 |
2.987 |
9.109e-03 |
0.398 |
-2.477 |
HS2ST1 |
heparan sulfate 2-O-sulfotransferase 1 |
1 |
87152922, 87152922 |
NM_012262 |
9653 |
1p31.1-p22.1 |
Hs.719144 |
9 |
Golgi apparatus membrane integral to membrane transferase activity |
Heparan sulfate biosynthesis |
206587_at |
0.553 |
5.253 |
3.582 |
2.673e-03 |
0.290 |
-1.434 |
CCT6B |
chaperonin containing TCP1, subunit 6B (zeta 2) |
17 |
-30279050 |
NM_006584 |
10693 |
17q12 |
Hs.73072 |
9 |
nucleotide binding ATP binding cytoplasm protein folding spermatogenesis protein transporter activity unfolded protein binding chaperone-mediated protein complex assembly |
|
201671_x_at |
USP14 |
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
18 |
148482 |
BC003556 |
9097 |
18p11.32 |
Hs.464416 Hs.707058 |
15 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity |
|
209741_x_at |
SCAPER |
S-phase cyclin A-associated protein in the ER |
15 |
-74427583, -74427583 |
AF119814 |
49855 |
15q24 |
Hs.458986 |
7 |
intracellular nucleus endoplasmic reticulum zinc ion binding metal ion binding |
|
204408_at |
-0.297 |
5.554 |
-2.927 |
1.029e-02 |
0.418 |
-2.581 |
APEX2 |
APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
X |
55043504 |
NM_014481 |
27301 |
Xp11.21 |
Hs.659558 |
8 |
DNA binding DNA-(apurinic or apyrimidinic site) lyase activity endonuclease activity intracellular nucleus mitochondrion DNA repair response to DNA damage stimulus zinc ion binding lyase activity |
Base excision repair |
209018_s_at |
0.332 |
9.533 |
2.690 |
1.665e-02 |
0.465 |
-2.988 |
PINK1 |
PTEN induced putative kinase 1 |
1 |
20832534 |
BF432478 |
65018 |
1p36 |
Hs.389171 |
105 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding mitochondrion mitochondrial outer membrane protein amino acid phosphorylation response to stress protein kinase cascade membrane integral to membrane transferase activity positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion |
Parkinson's disease |
202156_s_at |
CUGBP2 |
CUG triplet repeat, RNA binding protein 2 |
10 |
11087264, 11099898, 11246998 |
N36839 |
10659 |
10p13 |
Hs.309288 |
25 |
nucleotide binding RNA binding protein binding nucleus cytoplasm mRNA processing regulation of heart contraction |
|
218876_at |
1.299 |
6.526 |
3.204 |
5.832e-03 |
0.357 |
-2.098 |
TPPP3 |
tubulin polymerization-promoting protein family member 3 |
16 |
-65981212 |
NM_016140 |
51673 |
16q22.1 |
Hs.534458 |
8 |
|
|
208485_x_at |
0.677 |
7.301 |
3.981 |
1.175e-03 |
0.231 |
-0.736 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
NM_003879 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
208815_x_at |
0.397 |
7.873 |
2.932 |
1.019e-02 |
0.417 |
-2.572 |
HSPA4 |
heat shock 70kDa protein 4 |
5 |
132415560 |
AB023420 |
3308 |
5q31.1-q31.2 |
Hs.90093 |
108 |
nucleotide binding ATP binding nucleus cytoplasm response to unfolded protein cellular chaperone-mediated protein complex assembly mitochondrial outer membrane translocase complex assembly |
Antigen processing and presentation |
236192_at |
HOOK3 |
hook homolog 3 (Drosophila) |
8 |
42871189 |
BF447112 |
84376 |
8p11.21 |
Hs.162852 |
13 |
cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex |
|
214552_s_at |
0.714 |
5.461 |
2.711 |
1.596e-02 |
0.459 |
-2.952 |
RABEP1 |
rabaptin, RAB GTPase binding effector protein 1 |
17 |
5126281 |
AF098638 |
9135 |
17p13.2 |
Hs.584784 Hs.592121 |
19 |
GTPase activator activity protein binding cytoplasm early endosome endocytosis apoptosis membrane fusion growth factor activity protein transport recycling endosome |
Endocytosis |
204417_at |
GALC |
galactosylceramidase |
14 |
-87499410, -87469110 |
NM_000153 |
2581 |
14q31 |
Hs.513439 |
27 |
galactosylceramidase activity lysosome carbohydrate metabolic process galactosylceramide catabolic process metabolic process hydrolase activity, acting on glycosyl bonds cation binding |
Sphingolipid metabolism Metabolic pathways Lysosome |
209840_s_at |
1.116 |
5.365 |
3.488 |
3.245e-03 |
0.306 |
-1.599 |
LRRN3 |
leucine rich repeat neuronal 3 |
7 |
110518297 |
AI221950 |
54674 |
7q31.1 |
Hs.3781 |
6 |
protein binding membrane integral to membrane |
|
227970_at |
-0.808 |
8.917 |
-4.064 |
9.921e-04 |
0.223 |
-0.594 |
GPR157 |
G protein-coupled receptor 157 |
1 |
-9087062 |
AK026883 |
80045 |
1p36.23 |
Hs.632367 |
5 |
G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane |
|
211954_s_at |
0.237 |
9.184 |
2.338 |
3.346e-02 |
0.552 |
-3.572 |
IPO5 |
importin 5 |
13 |
97403929 |
BC000947 |
3843 |
13q32.2 |
Hs.712598 |
53 |
protein import into nucleus, docking GTPase inhibitor activity protein binding nucleus nuclear pore nucleolus cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport Ran GTPase binding protein transporter activity interspecies interaction between organisms |
|
228728_at |
-0.494 |
9.498 |
-3.456 |
3.463e-03 |
0.308 |
-1.654 |
C7orf58 |
chromosome 7 open reading frame 58 |
7 |
120415986, 120416680 |
BF724137 |
79974 |
7q31.31 |
Hs.189652 |
13 |
endoplasmic reticulum |
|
206625_at |
0.849 |
6.668 |
2.336 |
3.354e-02 |
0.552 |
-3.574 |
PRPH2 |
peripherin 2 (retinal degeneration, slow) |
6 |
-42772310 |
NM_000322 |
5961 |
6p21.2-p12.3 |
Hs.654489 |
57 |
protein binding cell adhesion visual perception membrane integral to membrane response to stimulus retina development in camera-type eye |
Amyotrophic lateral sclerosis (ALS) |
213224_s_at |
0.268 |
6.000 |
2.161 |
4.706e-02 |
0.584 |
-3.854 |
NCRNA00081 |
non-protein coding RNA 81 |
10 |
-112648478, -112648478 |
AK025724 |
92482 |
10q25.2 |
Hs.232543 Hs.651480 |
4 |
cytoplasm cilium |
|
235798_at |
TMEM170B |
transmembrane protein 170B |
6 |
11646496 |
BE671123 |
100113407 |
6p24.2 |
Hs.146317 |
1 |
membrane integral to membrane |
|
35254_at |
TRAFD1 |
TRAF-type zinc finger domain containing 1 |
12 |
111047731 |
AB007447 |
10906 |
12q |
Hs.5148 |
10 |
protein binding intracellular zinc ion binding metal ion binding |
|
231875_at |
0.798 |
4.875 |
3.636 |
2.390e-03 |
0.284 |
-1.339 |
KIF21A |
kinesin family member 21A |
12 |
-37973296 |
AF155117 |
55605 |
12q12 |
Hs.374201 |
25 |
nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement |
|
219760_at |
LIN7B |
lin-7 homolog B (C. elegans) |
19 |
54309429 |
NM_022165 |
64130 |
19q13.3 |
Hs.221737 |
15 |
protein binding plasma membrane tight junction exocytosis neurotransmitter secretion protein transport synaptosome cell junction synapse postsynaptic membrane |
|
242287_at |
0.711 |
6.343 |
3.245 |
5.351e-03 |
0.351 |
-2.024 |
CLIP1 |
CAP-GLY domain containing linker protein 1 |
12 |
-121321933 |
AI090487 |
6249 |
12q24.3 |
Hs.524809 |
37 |
kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding |
|
234325_at |
C2orf65 |
chromosome 2 open reading frame 65 |
2 |
-74638517 |
Y12839 |
130951 |
2p13.1 |
Hs.348645 |
3 |
|
|
242757_at |
MDGA1 |
MAM domain containing glycosylphosphatidylinositol anchor 1 |
6 |
-37708261 |
BE730067 |
266727 |
6p21 |
Hs.437993 |
6 |
neuron migration molecular_function plasma membrane multicellular organismal development nervous system development brain development spinal cord association neuron differentiation cell differentiation anchored to plasma membrane |
|
224164_at |
1.150 |
5.235 |
2.659 |
1.770e-02 |
0.473 |
-3.039 |
TPM3 |
tropomyosin 3 |
1 |
-152400913, -152394403 |
AY004867 |
7170 |
1q21.2 |
Hs.535581 Hs.644306 Hs.654421 |
66 |
molecular_function actin binding protein binding cytoplasm cytoskeleton cytoskeleton muscle thin filament tropomyosin cell motion regulation of muscle contraction |
Cardiac muscle contraction Pathways in cancer Thyroid cancer Hypertrophic cardiomyopathy (HCM) |
210829_s_at |
0.646 |
6.766 |
3.619 |
2.473e-03 |
0.287 |
-1.368 |
SSBP2 |
single-stranded DNA binding protein 2 |
5 |
-80751427 |
AF077048 |
23635 |
5q14.1 |
Hs.102735 |
14 |
DNA binding single-stranded DNA binding protein binding nucleus cytoplasm transcription regulator activity regulation of transcription |
|
219872_at |
C4orf18 |
chromosome 4 open reading frame 18 |
4 |
-159265181, -159265181 |
NM_016613 |
51313 |
4q32.1 |
Hs.567498 |
9 |
Golgi apparatus membrane integral to membrane |
|
218364_at |
LRRFIP2 |
leucine rich repeat (in FLII) interacting protein 2 |
3 |
-37069120 |
NM_017724 |
9209 |
3p22.2 |
Hs.719246 |
7 |
protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding |
|
213400_s_at |
0.429 |
6.514 |
2.525 |
2.316e-02 |
0.506 |
-3.265 |
TBL1X |
transducin (beta)-like 1X-linked |
X |
9391334, 9393200 |
AV753028 |
6907 |
Xp22.3 |
Hs.495656 |
16 |
nucleus signal transduction visual perception sensory perception of sound modification-dependent protein catabolic process regulation of transcription |
Wnt signaling pathway |
1552616_a_at |
-0.355 |
5.767 |
-3.316 |
4.622e-03 |
0.334 |
-1.900 |
ACACB |
acetyl-Coenzyme A carboxylase beta |
12 |
108061584 |
NM_001093 |
32 |
12q24.11 |
Hs.234898 |
22 |
nucleotide binding acetyl-CoA carboxylase activity biotin carboxylase activity ATP binding cytoplasm Golgi apparatus cytosol fatty acid biosynthetic process metabolic process biotin binding membrane ligase activity manganese ion binding regulation of fatty acid oxidation metal ion binding |
Fatty acid biosynthesis Pyruvate metabolism Propanoate metabolism Metabolic pathways Insulin signaling pathway Adipocytokine signaling pathway |
243026_x_at |
0.231 |
7.068 |
2.442 |
2.730e-02 |
0.526 |
-3.403 |
XIAP |
X-linked inhibitor of apoptosis |
X |
122821728 |
BE380045 |
331 |
Xq25 |
Hs.356076 |
170 |
protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding |
Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer |
200721_s_at |
0.280 |
7.848 |
2.419 |
2.852e-02 |
0.532 |
-3.439 |
ACTR1A |
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) |
10 |
-104228976 |
NM_005736 |
10121 |
10q24.32 |
Hs.153961 |
26 |
nucleotide binding protein binding ATP binding cytoplasm centrosome cytoskeleton dynactin complex vesicle-mediated transport |
|
226211_at |
MEG3 |
maternally expressed 3 (non-protein coding) |
14 |
100362197, 100362215 |
AI291123 |
55384 |
14q32 |
Hs.525589 Hs.593706 Hs.654863 Hs.655127 |
11 |
|
|
200836_s_at |
0.461 |
8.420 |
3.076 |
7.582e-03 |
0.378 |
-2.321 |
MAP4 |
microtubule-associated protein 4 |
3 |
-47989573, -47867183, -47867183 |
NM_002375 |
4134 |
3p21 |
Hs.517949 |
40 |
structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
203002_at |
0.981 |
6.784 |
4.048 |
1.024e-03 |
0.225 |
-0.620 |
AMOTL2 |
angiomotin like 2 |
3 |
-135556879 |
NM_016201 |
51421 |
3q21-q22 |
Hs.426312 Hs.713601 |
9 |
tight junction identical protein binding |
|
203666_at |
CXCL12 |
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) |
10 |
-44192515, -44191370, -44185610 |
NM_000609 |
6387 |
10q11.1 |
Hs.522891 |
435 |
signal transducer activity extracellular region extracellular space cellular calcium ion homeostasis chemotaxis immune response cell adhesion signal transduction G-protein coupled receptor protein signaling pathway chemokine activity blood circulation regulation of actin polymerization or depolymerization growth factor activity response to virus |
Cytokine-cytokine receptor interaction Chemokine signaling pathway Axon guidance Leukocyte transendothelial migration |
1555814_a_at |
0.619 |
9.327 |
3.608 |
2.534e-03 |
0.287 |
-1.388 |
RHOA |
ras homolog gene family, member A |
3 |
-49371582 |
AF498970 |
387 |
3p21.3 |
Hs.247077 Hs.709788 |
348 |
nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation |
Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer |
226782_at |
-0.849 |
9.912 |
-3.393 |
3.945e-03 |
0.321 |
-1.765 |
SLC25A30 |
solute carrier family 25, member 30 |
13 |
-44865455 |
BF001919 |
253512 |
13q14.13 |
Hs.591230 |
3 |
binding mitochondrion mitochondrial inner membrane transport mitochondrial transport membrane integral to membrane |
|
1555600_s_at |
-0.175 |
4.705 |
-2.244 |
4.012e-02 |
0.569 |
-3.723 |
APOL4 |
apolipoprotein L, 4 |
22 |
-34915121 |
AF305226 |
80832 |
22q11.2-q13.2 |
Hs.115099 |
9 |
molecular_function extracellular region lipid metabolic process lipid transport lipid binding lipoprotein metabolic process |
|
225643_at |
MAPK1IP1L |
mitogen-activated protein kinase 1 interacting protein 1-like |
14 |
54588114 |
AI261542 |
93487 |
14q22.3 |
Hs.594338 Hs.619374 |
8 |
|
|
213982_s_at |
0.738 |
4.676 |
3.063 |
7.780e-03 |
0.381 |
-2.343 |
RABGAP1L |
RAB GTPase activating protein 1-like |
1 |
172395256, 173111306 |
BG107203 |
9910 |
1q24 |
Hs.585378 |
9 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
242905_at |
PNO1 |
partner of NOB1 homolog (S. cerevisiae) |
2 |
68238508 |
AV733347 |
56902 |
2p14 |
Hs.262858 |
8 |
RNA binding nucleus nucleolus |
|
222657_s_at |
0.562 |
6.919 |
2.940 |
1.001e-02 |
0.414 |
-2.557 |
UBE2W |
ubiquitin-conjugating enzyme E2W (putative) |
8 |
-74865393 |
AK024050 |
55284 |
8q21.11 |
Hs.597486 |
7 |
nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
224461_s_at |
0.605 |
5.674 |
4.077 |
9.658e-04 |
0.223 |
-0.571 |
AIFM2 |
apoptosis-inducing factor, mitochondrion-associated, 2 |
10 |
-71542035 |
BC006121 |
84883 |
10q22.1 |
Hs.655377 |
13 |
DNA binding electron-transferring-flavoprotein dehydrogenase activity electron-transferring-flavoprotein dehydrogenase activity cytoplasm mitochondrion mitochondrial outer membrane cytosol induction of apoptosis apoptotic mitochondrial changes membrane integral to membrane oxidoreductase activity chromosome condensation FAD binding oxidation reduction |
|
221217_s_at |
0.537 |
9.440 |
3.502 |
3.150e-03 |
0.304 |
-1.573 |
A2BP1 |
ataxin 2-binding protein 1 |
16 |
6009132, 6763810, 7322751 |
NM_018723 |
54715 |
16p13.3 |
Hs.459842 |
22 |
nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport |
|
1565786_x_at |
FLJ45482 |
hypothetical LOC645566 |
7 |
|
BQ953917 |
645566 |
|
Hs.644332 |
1 |
|
|
225418_at |
-0.273 |
6.457 |
-2.791 |
1.357e-02 |
0.438 |
-2.815 |
PVRL2 |
poliovirus receptor-related 2 (herpesvirus entry mediator B) |
19 |
50041232, 50041232 |
AI520949 |
5819 |
19q13.2 |
Hs.655455 |
38 |
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of immunoglobulin mediated immune response plasma membrane cell-cell junction zonula adherens cell adhesion homophilic cell adhesion spermatid development cell surface coreceptor activity integral to membrane viral envelope fusion with host membrane positive regulation of mast cell activation susceptibility to natural killer cell mediated cytotoxicity virion attachment, binding of host cell surface coreceptor cell adhesion molecule binding adhesion to symbiont susceptibility to T cell mediated cytotoxicity |
Cell adhesion molecules (CAMs) Adherens junction |
230943_at |
-0.494 |
3.688 |
-2.574 |
2.098e-02 |
0.497 |
-3.182 |
SOX17 |
SRY (sex determining region Y)-box 17 |
8 |
55533047 |
AI821669 |
64321 |
8q11.23 |
Hs.98367 |
15 |
angiogenesis vasculogenesis DNA binding nucleus beta-catenin binding transcription factor binding negative regulation of Wnt receptor signaling pathway protein destabilization regulation of transcription protein stabilization |
Wnt signaling pathway |
224314_s_at |
0.495 |
5.655 |
2.509 |
2.391e-02 |
0.509 |
-3.292 |
EGLN1 |
egl nine homolog 1 (C. elegans) |
1 |
-229566120 |
AF277174 |
54583 |
1q42.1 |
Hs.444450 Hs.710300 |
42 |
response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction |
Pathways in cancer Renal cell carcinoma |
218517_at |
PHF17 |
PHD finger protein 17 |
4 |
129950228, 129950228 |
NM_024900 |
79960 |
4q26-q27 |
Hs.12420 |
14 |
histone acetyltransferase complex protein binding nucleus cytoplasm apoptosis response to stress zinc ion binding negative regulation of cell growth histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation regulation of transcription metal ion binding |
|
227279_at |
0.616 |
7.300 |
2.729 |
1.537e-02 |
0.457 |
-2.920 |
TCEAL3 |
transcription elongation factor A (SII)-like 3 |
X |
102749489 |
AA847654 |
85012 |
Xq22.2 |
Hs.311776 |
6 |
nucleus regulation of transcription |
|
222989_s_at |
UBQLN1 |
ubiquilin 1 |
9 |
-85464697 |
NM_013438 |
29979 |
9q21.2-q21.3 9q22 |
Hs.9589 |
46 |
nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm |
|
206461_x_at |
1.062 |
10.334 |
4.843 |
2.067e-04 |
0.172 |
0.717 |
MT1H |
metallothionein 1H |
16 |
55261226 |
NM_005951 |
4496 |
16q13 |
Hs.438462 |
16 |
copper ion binding protein binding zinc ion binding cadmium ion binding metal ion binding |
|
200098_s_at |
ANAPC5 |
anaphase promoting complex subunit 5 |
12 |
-120230432, -120230432 |
T33068 |
51433 |
12q24.31 |
Hs.7101 |
28 |
G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
238613_at |
ZAK |
sterile alpha motif and leucine zipper containing kinase AZK |
2 |
173648810, 173648810 |
AI475164 |
51776 |
2q24.2 |
Hs.444451 |
24 |
cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis |
MAPK signaling pathway Tight junction |
221497_x_at |
0.444 |
7.147 |
2.292 |
3.660e-02 |
0.560 |
-3.647 |
EGLN1 |
egl nine homolog 1 (C. elegans) |
1 |
-229566120 |
BC005369 |
54583 |
1q42.1 |
Hs.444450 Hs.710300 |
42 |
response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction |
Pathways in cancer Renal cell carcinoma |
207154_at |
DIO3 |
deiodinase, iodothyronine, type III |
14 |
101097440 |
NM_001362 |
1735 |
14q32 |
Hs.49322 |
19 |
thyroxine 5'-deiodinase activity cellular_component endosome plasma membrane biological_process selenium binding integral to membrane thyroxine 5-deiodinase activity positive regulation of multicellular organism growth thyroid hormone catabolic process hormone biosynthetic process oxidation reduction |
|
217997_at |
0.476 |
3.562 |
3.074 |
7.608e-03 |
0.378 |
-2.324 |
PHLDA1 |
pleckstrin homology-like domain, family A, member 1 |
12 |
-74705493 |
AI795908 |
22822 |
12q15 |
Hs.602085 |
15 |
protein binding nucleus nucleolus cytoplasm apoptosis membrane cytoplasmic vesicle membrane cytoplasmic vesicle FasL biosynthetic process |
|
217681_at |
WNT7B |
wingless-type MMTV integration site family, member 7B |
22 |
-44694913 |
BE736994 |
7477 |
22q13 |
Hs.512714 |
10 |
signal transducer activity extracellular matrix structural constituent extracellular region proteinaceous extracellular matrix Wnt receptor signaling pathway, calcium modulating pathway cell-cell signaling multicellular organismal development organ morphogenesis positive regulation of osteoblast differentiation synapse organization |
Wnt signaling pathway Hedgehog signaling pathway Melanogenesis Pathways in cancer Basal cell carcinoma |
40687_at |
-0.352 |
6.474 |
-2.953 |
9.763e-03 |
0.408 |
-2.536 |
GJA4 |
gap junction protein, alpha 4, 37kDa |
1 |
35031185 |
M96789 |
2701 |
1p35.1 |
Hs.296310 |
47 |
blood vessel development plasma membrane integral to plasma membrane connexon complex transport cell-cell junction assembly cell communication cell junction |
|
218984_at |
0.351 |
6.570 |
2.486 |
2.499e-02 |
0.513 |
-3.329 |
PUS7 |
pseudouridylate synthase 7 homolog (S. cerevisiae) |
7 |
-104884195 |
NM_019042 |
54517 |
7q22.3 |
Hs.520619 |
5 |
pseudouridine synthesis RNA binding tRNA processing pseudouridine synthase activity isomerase activity |
|
209503_s_at |
0.285 |
9.753 |
2.442 |
2.726e-02 |
0.526 |
-3.402 |
PSMC5 |
proteasome (prosome, macropain) 26S subunit, ATPase, 5 |
17 |
59258541 |
AF035309 |
5705 |
17q23-q25 |
Hs.79387 |
71 |
nucleotide binding proteasome complex transcription cofactor activity ATP binding nucleus nucleolus cytoplasm cytosol transcription from RNA polymerase II promoter hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process thyrotropin-releasing hormone receptor binding negative regulation of programmed cell death positive regulation of gene-specific transcription negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
210330_at |
0.365 |
4.597 |
2.224 |
4.169e-02 |
0.573 |
-3.754 |
SGCD |
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
5 |
155686344, 155686344 |
U58331 |
6444 |
5q33-q34 |
Hs.387207 Hs.644733 |
29 |
protein binding cytoplasm cytoskeleton plasma membrane cytoskeleton organization muscle organ development sarcoglycan complex integral to membrane |
Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
218883_s_at |
MLF1IP |
MLF1 interacting protein |
4 |
-185852213 |
NM_024629 |
79682 |
4q35.1 |
Hs.575032 |
16 |
condensed chromosome kinetochore protein binding nucleus chromosome cytoplasm interspecies interaction between organisms regulation of transcription |
|
226466_s_at |
0.332 |
7.202 |
2.511 |
2.379e-02 |
0.509 |
-3.288 |
FAM58A |
family with sequence similarity 58, member A |
X |
-152506576 |
AL544688 |
92002 |
Xq28 |
Hs.496943 Hs.659433 |
6 |
|
|
220539_at |
0.509 |
6.761 |
2.584 |
2.059e-02 |
0.497 |
-3.166 |
C10orf92 |
chromosome 10 open reading frame 92 |
10 |
-134471886 |
NM_017609 |
54777 |
10q26.3 |
Hs.298038 |
6 |
|
|
91703_at |
EHBP1L1 |
EH domain binding protein 1-like 1 |
11 |
65100084 |
AA149545 |
254102 |
11q13.1 |
Hs.502867 |
4 |
|
|
200749_at |
RAN |
RAN, member RAS oncogene family |
12 |
129922569 |
BF112006 |
5901 |
12q24.3 |
Hs.10842 |
132 |
nucleotide binding chromatin chromatin binding transcription coactivator activity GTPase activity GTPase activity protein binding GTP binding nucleus nuclear pore nucleoplasm cytoplasm cytosol DNA metabolic process RNA export from nucleus protein export from nucleus intracellular protein transport nucleocytoplasmic transport mitotic spindle organization mitosis signal transduction androgen receptor signaling pathway melanosome interspecies interaction between organisms positive regulation of transcription, DNA-dependent androgen receptor binding |
|
202500_at |
0.246 |
8.154 |
2.332 |
3.386e-02 |
0.552 |
-3.582 |
DNAJB2 |
DnaJ (Hsp40) homolog, subfamily B, member 2 |
2 |
219852283 |
NM_006736 |
3300 |
2q32-q34 |
Hs.77768 |
17 |
protein folding response to unfolded protein heat shock protein binding unfolded protein binding |
|
201955_at |
0.517 |
7.090 |
4.042 |
1.037e-03 |
0.225 |
-0.631 |
CCNC |
cyclin C |
6 |
-100096983 |
AL137784 |
892 |
6q21 |
Hs.430646 Hs.633351 |
31 |
protein binding nucleus regulation of transcription |
|
205417_s_at |
0.274 |
9.122 |
2.493 |
2.466e-02 |
0.513 |
-3.318 |
DAG1 |
dystroglycan 1 (dystrophin-associated glycoprotein 1) |
3 |
49482568 |
NM_004393 |
1605 |
3p21 |
Hs.707131 Hs.76111 |
56 |
morphogenesis of an epithelial sheet calcium ion binding protein binding extracellular region basement membrane extracellular space membrane fraction cytoplasm integral to plasma membrane protein complex assembly muscle contraction actin cytoskeleton dystroglycan complex sarcolemma membrane raft |
ECM-receptor interaction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
228363_at |
XIAP |
X-linked inhibitor of apoptosis |
X |
122821728 |
BF109251 |
331 |
Xq25 |
Hs.356076 |
170 |
protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding |
Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer |
233403_x_at |
TM6SF2 |
transmembrane 6 superfamily member 2 |
19 |
-19236173 |
AK026307 |
53345 |
19p13.3-p12 |
Hs.531624 |
6 |
molecular_function biological_process membrane integral to membrane |
|
202861_at |
PER1 |
period homolog 1 (Drosophila) |
17 |
-7984512 |
NM_002616 |
5187 |
17p13.1-p12 |
Hs.445534 |
54 |
signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction circadian rhythm entrainment of circadian clock negative regulation of transcription |
Circadian rhythm - mammal |
34471_at |
MYH8 |
myosin, heavy chain 8, skeletal muscle, perinatal |
17 |
-10234366 |
M36769 |
4626 |
17p13.1 |
Hs.700484 |
10 |
nucleotide binding motor activity actin binding calmodulin binding ATP binding cytoplasm striated muscle thick filament striated muscle contraction structural constituent of muscle myosin complex myofibril |
Tight junction |
202009_at |
TWF2 |
twinfilin, actin-binding protein, homolog 2 (Drosophila) |
3 |
-52237665 |
NM_007284 |
11344 |
3p21.1 |
Hs.436439 |
9 |
actin binding protein binding ATP binding intracellular cytoplasm cytoskeleton perinuclear region of cytoplasm |
|
204204_at |
SLC31A2 |
solute carrier family 31 (copper transporters), member 2 |
9 |
114953058 |
NM_001860 |
1318 |
9q31-q32 |
Hs.24030 |
7 |
copper ion transmembrane transporter activity copper ion binding integral to plasma membrane ion transport copper ion transport membrane |
|
223013_at |
0.301 |
9.210 |
2.544 |
2.228e-02 |
0.500 |
-3.233 |
TBL1XR1 |
transducin (beta)-like 1 X-linked receptor 1 |
3 |
-178221235 |
AF267864 |
79718 |
3q26.32 |
Hs.715537 |
14 |
nucleus chromatin modification modification-dependent protein catabolic process regulation of transcription |
Wnt signaling pathway |
224177_s_at |
CXorf26 |
chromosome X open reading frame 26 |
X |
75309172 |
AF151079 |
51260 |
Xq13.3 |
Hs.370100 |
6 |
molecular_function cellular_component biological_process |
|
214093_s_at |
FUBP1 |
far upstream element (FUSE) binding protein 1 |
1 |
-78186178 |
AA156865 |
8880 |
1p31.1 |
Hs.567380 |
28 |
single-stranded DNA binding transcription factor activity RNA binding protein binding nucleus nucleolus transcription from RNA polymerase II promoter regulation of transcription |
|
239213_at |
-0.270 |
4.754 |
-2.398 |
2.972e-02 |
0.536 |
-3.474 |
SERPINB1 |
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
6 |
-2778732 |
W52010 |
1992 |
6p25 |
Hs.381167 |
18 |
serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity |
|
1562264_at |
-0.268 |
3.463 |
-2.965 |
9.525e-03 |
0.403 |
-2.515 |
LOC339685 |
hypothetical protein LOC339685 |
22 |
|
BC043000 |
339685 |
22q13.31 |
Hs.434351 |
1 |
|
|
218631_at |
0.381 |
5.876 |
3.029 |
8.350e-03 |
0.388 |
-2.403 |
AVPI1 |
arginine vasopressin-induced 1 |
10 |
-99427170 |
NM_021732 |
60370 |
10q24.2 |
Hs.23918 |
9 |
cell cycle |
|
1554565_x_at |
-0.289 |
6.547 |
-2.761 |
1.441e-02 |
0.447 |
-2.866 |
UNQ1887 |
signal peptide peptidase 3 |
12 |
-119685417 |
BC011943 |
121665 |
12q24.31 |
Hs.507087 Hs.683964 |
12 |
aspartic-type endopeptidase activity peptidase activity membrane integral to membrane |
|
202211_at |
ARFGAP3 |
ADP-ribosylation factor GTPase activating protein 3 |
22 |
-41522475 |
BC005122 |
26286 |
22q13.2-q13.3 |
Hs.162877 |
15 |
cytoplasm Golgi apparatus cytosol intracellular protein transport ARF GTPase activator activity zinc ion binding protein transporter activity protein secretion membrane vesicle-mediated transport regulation of ARF GTPase activity metal ion binding |
Endocytosis |
208722_s_at |
0.443 |
7.308 |
2.902 |
1.084e-02 |
0.421 |
-2.624 |
ANAPC5 |
anaphase promoting complex subunit 5 |
12 |
-120230432, -120230432 |
BC001081 |
51433 |
12q24.31 |
Hs.7101 |
28 |
G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
205150_s_at |
0.765 |
5.425 |
3.974 |
1.191e-03 |
0.233 |
-0.748 |
KIAA0644 |
KIAA0644 gene product |
7 |
-28959498 |
AV724192 |
9865 |
7p14.3 |
Hs.719240 |
4 |
protein binding membrane integral to membrane |
|
200835_s_at |
MAP4 |
microtubule-associated protein 4 |
3 |
-47989573, -47867183, -47867183 |
AI553791 |
4134 |
3p21 |
Hs.517949 |
40 |
structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
209750_at |
-1.553 |
6.636 |
-3.274 |
5.044e-03 |
0.345 |
-1.974 |
NR1D2 |
nuclear receptor subfamily 1, group D, member 2 |
3 |
23961754, 23962615 |
N32859 |
9975 |
3p24.2 |
Hs.37288 |
13 |
transcription factor activity steroid hormone receptor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding |
|
235539_at |
NUMA1 |
nuclear mitotic apparatus protein 1 |
11 |
-71391558 |
AW964431 |
4926 |
11q13 |
Hs.325978 |
47 |
mitotic anaphase spindle pole structural molecule activity protein binding nucleus spindle microtubule nucleus organization microtubule binding nuclear matrix dendrite cell soma meiotic cell cycle |
|
221252_s_at |
GSG1 |
germ cell associated 1 |
12 |
-13128308, -13128308 |
NM_031289 |
83445 |
12p13.1 |
Hs.240053 |
7 |
endoplasmic reticulum membrane integral to membrane |
|
227418_at |
KIAA1826 |
KIAA1826 |
11 |
-105383838 |
AI808746 |
84437 |
11q22 |
Hs.266782 |
8 |
nucleus |
|
1553267_a_at |
-0.208 |
2.281 |
-2.482 |
2.522e-02 |
0.514 |
-3.337 |
CNOT6L |
CCR4-NOT transcription complex, subunit 6-like |
4 |
-78853564 |
NM_144571 |
246175 |
4q13.3 |
Hs.592519 |
5 |
exonuclease activity protein binding cytoplasm mRNA processing hydrolase activity |
RNA degradation |
229026_at |
CDC42SE2 |
CDC42 small effector 2 |
5 |
130627600 |
BE675995 |
56990 |
5q23.3-q31.1 |
Hs.508829 Hs.713870 |
8 |
structural molecule activity protein binding cytoplasm cytoskeleton plasma membrane phagocytosis regulation of cell shape regulation of signal transduction |
|
203977_at |
TAZ |
tafazzin |
X |
153293070 |
NM_000116 |
6901 |
Xq28 |
Hs.409911 |
35 |
cytoplasm mitochondrion mitochondrion muscle contraction skeletal muscle tissue development metabolic process acyltransferase activity membrane integral to membrane hemopoiesis cardiolipin biosynthetic process mitochondrial respiratory chain complex I assembly cristae formation mitochondrial ATP synthesis coupled electron transport 1-acylglycerophosphocholine O-acyltransferase activity cardiac muscle tissue development cardiac muscle contraction |
|
222693_at |
0.320 |
3.374 |
2.711 |
1.593e-02 |
0.459 |
-2.950 |
FNDC3B |
fibronectin type III domain containing 3B |
3 |
173240111, 173241037 |
BF444916 |
64778 |
3q26.31 |
Hs.159430 |
9 |
endoplasmic reticulum membrane integral to membrane |
|
1553895_at |
C11orf42 |
chromosome 11 open reading frame 42 |
11 |
6183373 |
NM_173525 |
160298 |
11p15.4 |
Hs.278221 |
2 |
|
|
217870_s_at |
CMPK1 |
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic |
1 |
47572055 |
NM_016308 |
51727 |
1p32 |
Hs.714325 |
16 |
nucleotide binding cytidylate kinase activity uridine kinase activity ATP binding nucleus cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process pyrimidine ribonucleotide biosynthetic process transferase activity phosphotransferase activity, phosphate group as acceptor |
Pyrimidine metabolism Metabolic pathways |
201198_s_at |
0.452 |
8.426 |
2.905 |
1.075e-02 |
0.420 |
-2.618 |
PSMD1 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 |
2 |
231629852 |
AI860431 |
5707 |
2q37.1 |
Hs.3887 |
43 |
proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
212717_at |
0.285 |
6.963 |
2.710 |
1.599e-02 |
0.459 |
-2.954 |
PLEKHM1 |
pleckstrin homology domain containing, family M (with RUN domain) member 1 |
17 |
-40869048 |
AB002354 |
9842 |
17q21.31 |
Hs.514242 |
7 |
cytoplasm intracellular signaling cascade zinc ion binding diacylglycerol binding metal ion binding |
|
202154_x_at |
TUBB3 |
tubulin, beta 3 |
16 |
88517245 |
NM_006086 |
10381 |
16q24.3 |
Hs.511743 |
41 |
nucleotide binding GTPase activity structural molecule activity GTP binding intracellular microtubule microtubule-based movement mitosis neuron differentiation axon protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
226089_at |
RABL3 |
RAB, member of RAS oncogene family-like 3 |
3 |
-121888217 |
AI742028 |
285282 |
3q13.33 |
Hs.444360 |
1 |
nucleotide binding GTP binding intracellular small GTPase mediated signal transduction |
|
226164_x_at |
0.560 |
5.187 |
2.970 |
9.419e-03 |
0.401 |
-2.505 |
RIMKLB |
ribosomal modification protein rimK-like family member B |
12 |
8741784 |
AI760919 |
57494 |
12p13.31 |
Hs.504670 |
4 |
nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding |
|
222154_s_at |
0.421 |
9.172 |
2.412 |
2.894e-02 |
0.534 |
-3.452 |
SPATS2L |
spermatogenesis associated, serine-rich 2-like |
2 |
200878848, 200879229, 200879600 |
AK002064 |
26010 |
2q33.1 |
Hs.120323 |
9 |
|
|
211969_at |
HSP90AA1 |
heat shock protein 90kDa alpha (cytosolic), class A member 1 |
14 |
-101616827, -101616827 |
BG420237 |
3320 |
14q32.33 |
Hs.525600 Hs.700831 |
275 |
nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly |
Antigen processing and presentation Pathways in cancer Prostate cancer |
230284_at |
0.709 |
6.234 |
2.826 |
1.264e-02 |
0.429 |
-2.755 |
MYOM3 |
myomesin family, member 3 |
1 |
-24255117 |
BF108688 |
127294 |
1p36.11 |
Hs.523413 |
4 |
|
|
1552879_a_at |
-0.354 |
3.964 |
-3.471 |
3.360e-03 |
0.308 |
-1.628 |
ATOH7 |
atonal homolog 7 (Drosophila) |
10 |
-69660387 |
BC032621 |
220202 |
10q21.3 10q21.3-q22.1 |
Hs.175396 |
4 |
DNA binding nucleus multicellular organismal development nervous system development circadian rhythm entrainment of circadian clock cell differentiation transcription regulator activity regulation of transcription |
|
41037_at |
TEAD4 |
TEA domain family member 4 |
12 |
2938756, 2939222 |
U63824 |
7004 |
12p13.3-p13.2 |
Hs.94865 |
16 |
skeletal system development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter muscle organ development |
|
205402_x_at |
PRSS2 |
protease, serine, 2 (trypsin 2) |
7 |
142178777 |
NM_002770 |
5645 |
7q34 |
Hs.622865 |
39 |
serine-type endopeptidase activity calcium ion binding protein binding extracellular region extracellular space proteolysis digestion peptidase activity positive regulation of cell growth collagen catabolic process collagen catabolic process extracellular matrix positive regulation of cell adhesion |
Neuroactive ligand-receptor interaction |
212338_at |
0.716 |
2.782 |
3.770 |
1.814e-03 |
0.270 |
-1.104 |
MYO1D |
myosin ID |
17 |
-27843740 |
AA621962 |
4642 |
17q11-q12 |
Hs.658000 |
7 |
nucleotide binding motor activity actin binding calmodulin binding ATP binding myosin complex |
|
212712_at |
CAMSAP1 |
calmodulin regulated spectrin-associated protein 1 |
9 |
-137840153 |
BE222901 |
157922 |
9q34.3 |
Hs.522493 |
2 |
|
|
211758_x_at |
TXNDC9 |
thioredoxin domain containing 9 |
2 |
-99301918 |
BC005968 |
10190 |
2q11.2 |
Hs.536122 |
8 |
protein binding cellular_component biological_process |
|
214473_x_at |
0.287 |
6.323 |
2.308 |
3.543e-02 |
0.556 |
-3.620 |
PMS2L3 |
postmeiotic segregation increased 2-like 3 |
7 |
-74975005, -74975004 |
NM_005395 |
5387 |
7q11.23 |
Hs.406395 Hs.659871 Hs.661055 |
4 |
molecular_function nucleic acid binding ATP binding cellular_component intracellular regulation of transcription, DNA-dependent biological_process |
|
222918_at |
0.419 |
7.490 |
2.282 |
3.726e-02 |
0.562 |
-3.662 |
RAB9B |
RAB9B, member RAS oncogene family |
X |
-102966606 |
AL139228 |
51209 |
Xq22.1-q22.3 |
Hs.522736 Hs.679046 |
5 |
nucleotide binding protein binding GTP binding cellular_component plasma membrane Golgi to endosome transport small GTPase mediated signal transduction protein transport |
|
227277_at |
MTDH |
metadherin |
8 |
98725582 |
BG530089 |
92140 |
8q22.1 |
Hs.377155 |
23 |
negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity |
|
235653_s_at |
0.884 |
5.193 |
4.015 |
1.095e-03 |
0.227 |
-0.677 |
THAP6 |
THAP domain containing 6 |
4 |
76658677 |
BF685315 |
152815 |
4q21.1 |
Hs.479971 |
10 |
DNA binding zinc ion binding microtubule cytoskeleton metal ion binding |
|
219603_s_at |
0.370 |
4.885 |
2.579 |
2.078e-02 |
0.497 |
-3.174 |
ZNF226 |
zinc finger protein 226 |
19 |
49361088, 49361088, 49361096, 49361156 |
NM_015919 |
7769 |
19q13.2 |
Hs.145956 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
1554574_a_at |
0.549 |
5.646 |
3.857 |
1.517e-03 |
0.253 |
-0.953 |
CYB5R3 |
cytochrome b5 reductase 3 |
22 |
-41344757, -41344757 |
AF361370 |
1727 |
22q13.2-q13.31 22q13.31-qter |
Hs.700572 |
49 |
cytochrome-b5 reductase activity cytoplasm mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane hemoglobin complex cholesterol biosynthetic process blood circulation electron carrier activity membrane oxidoreductase activity oxidation reduction |
Amino sugar and nucleotide sugar metabolism |
225756_at |
-0.301 |
5.821 |
-2.981 |
9.210e-03 |
0.400 |
-2.486 |
CSNK1E |
casein kinase 1, epsilon |
22 |
-37016642, -37016642 |
AV762065 |
1454 |
22q13.1 |
Hs.474833 |
65 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm DNA repair protein amino acid phosphorylation signal transduction transferase activity |
Wnt signaling pathway Hedgehog signaling pathway Circadian rhythm - mammal |
214987_at |
-0.326 |
5.482 |
-3.195 |
5.940e-03 |
0.357 |
-2.113 |
GAB1 |
GRB2-associated binding protein 1 |
4 |
144477432 |
AL049449 |
2549 |
4q31.21 |
Hs.618456 Hs.80720 |
69 |
SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway |
ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma |
220606_s_at |
C17orf48 |
chromosome 17 open reading frame 48 |
17 |
10541651 |
NM_020233 |
56985 |
17p13.1 |
Hs.47668 Hs.708369 |
2 |
zinc ion binding hydrolase activity metal ion binding ADP-ribose diphosphatase activity CDP-glycerol diphosphatase activity |
|
200840_at |
-0.815 |
11.286 |
-4.192 |
7.628e-04 |
0.211 |
-0.372 |
KARS |
lysyl-tRNA synthetase |
16 |
-74219122 |
NM_005548 |
3735 |
16q23-q24 |
Hs.3100 |
30 |
nucleotide binding nucleic acid binding lysine-tRNA ligase activity ATP binding soluble fraction cytoplasm lysyl-tRNA aminoacylation ligase activity |
Aminoacyl-tRNA biosynthesis |
209276_s_at |
1.021 |
9.119 |
3.914 |
1.349e-03 |
0.245 |
-0.853 |
GLRX |
glutaredoxin (thioltransferase) |
5 |
-95175308 |
AF162769 |
2745 |
5q14 |
Hs.28988 Hs.712696 |
47 |
cytoplasm cytosol transport electron carrier activity protein disulfide oxidoreductase activity glutathione disulfide oxidoreductase activity electron transport chain cell redox homeostasis protein N-terminus binding |
|
203115_at |
0.816 |
5.892 |
3.555 |
2.823e-03 |
0.294 |
-1.480 |
FECH |
ferrochelatase (protoporphyria) |
18 |
-53363070 |
AU152635 |
2235 |
18q21.3 |
Hs.365365 |
61 |
ferrochelatase activity ferrochelatase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix generation of precursor metabolites and energy heme biosynthetic process ferrous iron binding response to light stimulus detection of UV membrane protoporphyrinogen IX metabolic process metal ion binding 2 iron, 2 sulfur cluster binding |
Porphyrin and chlorophyll metabolism Metabolic pathways |
210290_at |
0.541 |
4.178 |
4.857 |
2.010e-04 |
0.172 |
0.739 |
ZNF174 |
zinc finger protein 174 |
16 |
3391190, 3391190 |
BC001161 |
7727 |
16p13.3 |
Hs.155204 |
9 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding intracellular nucleus nucleolus cytoplasm cytoskeleton regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
214113_s_at |
RBM8A |
RNA binding motif protein 8A |
1 |
144218994 |
AI738479 |
9939 |
1q12 |
Hs.356873 |
43 |
nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport |
|
227421_at |
0.619 |
6.392 |
2.264 |
3.861e-02 |
0.567 |
-3.691 |
C21orf57 |
chromosome 21 open reading frame 57 |
21 |
46530694, 46530694 |
BF026326 |
54059 |
21q22.3 |
Hs.474066 |
4 |
peptidase activity metallopeptidase activity zinc ion binding metal ion binding |
|
223853_at |
0.601 |
4.122 |
3.132 |
6.759e-03 |
0.368 |
-2.223 |
BVES |
blood vessel epicardial substance |
6 |
-105651391, -105651391 |
AF204172 |
11149 |
6q21 |
Hs.221660 |
6 |
muscle organ development membrane integral to membrane |
|
221810_at |
RAB15 |
RAB15, member RAS onocogene family |
14 |
-64482284 |
AA631242 |
376267 |
14q23.3 |
Hs.512492 |
11 |
nucleotide binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport |
|
212435_at |
TRIM33 |
tripartite motif-containing 33 |
1 |
-114736921 |
AA205593 |
51592 |
1p13.1 |
Hs.26837 |
12 |
DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding |
|
211593_s_at |
0.249 |
7.952 |
2.322 |
3.451e-02 |
0.553 |
-3.598 |
MAST2 |
microtubule associated serine/threonine kinase 2 |
1 |
46041871 |
AB047005 |
23139 |
1p34.1 |
Hs.319481 |
19 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoskeleton plasma membrane protein amino acid phosphorylation transferase activity phosphatase binding regulation of interleukin-12 biosynthetic process spermatid differentiation |
|
33778_at |
TBC1D22A |
TBC1 domain family, member 22A |
22 |
45537212 |
AL096779 |
25771 |
22q13.3 |
Hs.435044 |
9 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
225658_at |
SPOPL |
speckle-type POZ protein-like |
2 |
138975819 |
BF034206 |
339745 |
2q22.1 |
Hs.333297 |
6 |
protein binding nucleus modification-dependent protein catabolic process |
|
229889_at |
C17orf76 |
chromosome 17 open reading frame 76 |
17 |
-16286052 |
AW137009 |
388341 |
17p11.2 |
Hs.25425 |
1 |
|
|
1562337_at |
0.503 |
4.318 |
2.500 |
2.430e-02 |
0.512 |
-3.306 |
OR7D2 |
olfactory receptor, family 7, subfamily D, member 2 |
19 |
9157269 |
AK095468 |
162998 |
19p13.2 |
Hs.531755 |
4 |
receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus |
Olfactory transduction |
203742_s_at |
0.381 |
5.727 |
2.775 |
1.402e-02 |
0.443 |
-2.843 |
TDG |
thymine-DNA glycosylase |
12 |
102883722 |
BF674842 |
6996 |
12q24.1 |
Hs.584809 |
47 |
damaged DNA binding protein binding nucleus nucleoplasm nucleoplasm base-excision repair mismatch repair response to DNA damage stimulus metabolic process pyrimidine-specific mismatch base pair DNA N-glycosylase activity DNA N-glycosylase activity mismatched DNA binding depyrimidination |
Base excision repair |
206443_at |
-0.349 |
3.757 |
-2.826 |
1.264e-02 |
0.429 |
-2.755 |
RORB |
RAR-related orphan receptor B |
9 |
76302071 |
NM_006914 |
6096 |
9q22 |
Hs.494178 |
16 |
transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development visual perception zinc ion binding eye photoreceptor cell development positive regulation of gene-specific transcription sequence-specific DNA binding metal ion binding response to stimulus |
|
46665_at |
SEMA4C |
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
2 |
-96889199 |
AI949392 |
54910 |
2q11.2 |
Hs.516220 |
9 |
receptor activity protein binding multicellular organismal development nervous system development membrane integral to membrane cell differentiation |
Axon guidance |
203837_at |
-0.663 |
6.437 |
-2.423 |
2.829e-02 |
0.531 |
-3.433 |
MAP3K5 |
mitogen-activated protein kinase kinase kinase 5 |
6 |
-136919879 |
NM_005923 |
4217 |
6q22.33 |
Hs.186486 |
108 |
MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding protein amino acid phosphorylation apoptosis activation of JUN kinase activity induction of apoptosis by extracellular signals caspase activator activity transferase activity protein homodimerization activity interspecies interaction between organisms |
MAPK signaling pathway Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) |
218184_at |
TULP4 |
tubby like protein 4 |
6 |
158653679 |
NM_020245 |
56995 |
6q25-q26 |
Hs.486993 |
7 |
transcription factor activity protein binding cellular_component cytoplasm regulation of transcription, DNA-dependent intracellular signaling cascade response to nutrient modification-dependent protein catabolic process |
|
203008_x_at |
0.316 |
7.997 |
2.148 |
4.818e-02 |
0.588 |
-3.873 |
TXNDC9 |
thioredoxin domain containing 9 |
2 |
-99301918 |
NM_005783 |
10190 |
2q11.2 |
Hs.536122 |
8 |
protein binding cellular_component biological_process |
|
204446_s_at |
0.810 |
3.702 |
5.503 |
5.770e-05 |
0.162 |
1.755 |
ALOX5 |
arachidonate 5-lipoxygenase |
10 |
45189634 |
NM_000698 |
240 |
10q11.2 |
Hs.89499 |
141 |
arachidonate 5-lipoxygenase activity iron ion binding calcium ion binding protein binding nucleus nuclear envelope lumen cytoplasm cytosol inflammatory response membrane lipoxygenase activity nuclear matrix oxidoreductase activity leukotriene biosynthetic process nuclear membrane oxidation reduction |
Arachidonic acid metabolism Linoleic acid metabolism Metabolic pathways |
225216_at |
CXorf39 |
chromosome X open reading frame 39 |
X |
103297956 |
AI590719 |
139231 |
Xq22.2 |
Hs.496535 Hs.592223 |
5 |
|
|
238664_s_at |
-0.193 |
4.773 |
-2.426 |
2.813e-02 |
0.529 |
-3.428 |
MGC12916 |
hypothetical protein MGC12916 |
17 |
14147781 |
BF205828 |
84815 |
17p12 |
Hs.597458 |
|
|
|
222510_s_at |
0.670 |
6.259 |
4.426 |
4.748e-04 |
0.193 |
0.026 |
MKRN2 |
makorin ring finger protein 2 |
3 |
12573593 |
AI809203 |
23609 |
3p25 |
Hs.591666 |
5 |
molecular_function nucleic acid binding protein binding intracellular biological_process zinc ion binding metal ion binding |
|
201646_at |
0.573 |
7.181 |
2.697 |
1.639e-02 |
0.464 |
-2.975 |
SCARB2 |
scavenger receptor class B, member 2 |
4 |
-77298917 |
AA885297 |
950 |
4q21.1 |
Hs.349656 Hs.714206 |
24 |
receptor activity protein binding membrane fraction lysosome integral to plasma membrane cell adhesion membrane |
Lysosome |
203282_at |
0.628 |
10.895 |
3.736 |
1.946e-03 |
0.273 |
-1.164 |
GBE1 |
glucan (1,4-alpha-), branching enzyme 1 |
3 |
-81621539 |
NM_000158 |
2632 |
3p12.3 |
Hs.436062 |
20 |
1,4-alpha-glucan branching enzyme activity 1,4-alpha-glucan branching enzyme activity hydrolase activity, hydrolyzing O-glycosyl compounds cytosol carbohydrate metabolic process glycogen biosynthetic process generation of precursor metabolites and energy transferase activity, transferring glycosyl groups cation binding |
Starch and sucrose metabolism Metabolic pathways |
200983_x_at |
CD59 |
CD59 molecule, complement regulatory protein |
11 |
-33681131, -33681131, -33681131 |
BF983379 |
966 |
11p13 |
Hs.278573 Hs.709466 Hs.710641 |
107 |
protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane |
Complement and coagulation cascades Hematopoietic cell lineage |
222612_at |
PSPC1 |
paraspeckle component 1 |
13 |
-19175008, -19146895 |
N32583 |
55269 |
13q12.11 |
Hs.213198 |
9 |
nucleotide binding RNA binding protein binding nucleus nucleolus cytoplasm nuclear matrix regulation of transcription |
|
205174_s_at |
2.051 |
4.526 |
4.379 |
5.229e-04 |
0.206 |
-0.055 |
QPCT |
glutaminyl-peptide cyclotransferase |
2 |
37425256 |
NM_012413 |
25797 |
2p22.2 |
Hs.79033 |
15 |
protein modification process proteolysis peptidase activity zinc ion binding acyltransferase activity glutaminyl-peptide cyclotransferase activity transferase activity metal ion binding |
|
221234_s_at |
0.741 |
4.931 |
3.255 |
5.250e-03 |
0.348 |
-2.008 |
BACH2 |
BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
6 |
-90692968 |
NM_021813 |
60468 |
6q15 |
Hs.269764 Hs.716609 Hs.716710 |
23 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity |
|
228121_at |
0.864 |
6.720 |
2.730 |
1.534e-02 |
0.457 |
-2.919 |
TGFB2 |
transforming growth factor, beta 2 |
1 |
216586013 |
AU145950 |
7042 |
1q41 |
Hs.133379 |
112 |
cell morphogenesis skeletal system development cartilage condensation angiogenesis beta-amyloid binding blood vessel development eye development response to hypoxia blood vessel remodeling receptor signaling protein serine/threonine kinase activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding cytokine activity extracellular region extracellular region extracellular region extracellular space induction of apoptosis activation-induced cell death of T cells cell cycle arrest transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation cell-cell signaling axon guidance salivary gland morphogenesis growth factor activity cell death positive regulation of cell proliferation glial cell migration embryonic development positive regulation of epithelial cell migration negative regulation of alkaline phosphatase activity positive regulation of epithelial to mesenchymal transition positive regulation of phosphoinositide 3-kinase cascade menstrual cycle phase hemopoiesis collagen fibril organization positive regulation of cell growth negative regulation of cell growth axon neutrophil chemotaxis neutrophil chemotaxis extracellular matrix hair follicle morphogenesis platelet alpha granule lumen activation of protein kinase activity response to progesterone stimulus positive regulation of stress-activated MAPK cascade regulation of transforming growth factor-beta2 production positive regulation of cell adhesion mediated by integrin wound healing dopamine biosynthetic process odontogenesis protein homodimerization activity cell soma positive regulation of neuron apoptosis cell-cell junction organization positive regulation of integrin biosynthetic process positive regulation of ossification positive regulation of cell cycle positive regulation of heart contraction protein heterodimerization activity somatic stem cell division neuron fate commitment neuron development generation of neurons negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive regulation of protein secretion negative regulation of immune response positive regulation of immune response positive regulation of catagen positive regulation of cardioblast differentiation cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition pathway-restricted SMAD protein phosphorylation |
MAPK signaling pathway Cytokine-cytokine receptor interaction Cell cycle TGF-beta signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hypertrophic cardiomyopathy (HCM) |
206718_at |
-0.458 |
8.041 |
-2.484 |
2.508e-02 |
0.513 |
-3.332 |
LMO1 |
LIM domain only 1 (rhombotin 1) |
11 |
-8202432 |
NM_002315 |
4004 |
11p15 |
Hs.654426 |
21 |
transcription factor activity nucleus multicellular organismal development zinc ion binding cell proliferation metal ion binding |
|
215818_at |
-0.257 |
4.591 |
-2.774 |
1.405e-02 |
0.444 |
-2.844 |
NUDT7 |
nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
16 |
76313911, 76313911 |
AK026469 |
283927 |
16q23.1 |
Hs.719356 |
2 |
magnesium ion binding peroxisome nucleoside diphosphate metabolic process hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides manganese ion binding |
|
219058_x_at |
TINAGL1 |
tubulointerstitial nephritis antigen-like 1 |
1 |
31814672 |
NM_022164 |
64129 |
1p35.2 |
Hs.199368 |
14 |
cysteine-type endopeptidase activity extracellular matrix structural constituent extracellular region proteolysis endosome transport |
|
219805_at |
-0.514 |
6.465 |
-3.469 |
3.372e-03 |
0.308 |
-1.631 |
CXorf56 |
chromosome X open reading frame 56 |
X |
-118557528 |
NM_022101 |
63932 |
Xq23 |
Hs.248572 |
3 |
protein binding |
|
209360_s_at |
1.082 |
6.890 |
3.189 |
6.012e-03 |
0.358 |
-2.124 |
RUNX1 |
runt-related transcription factor 1 |
21 |
-35115443, -35081967, -35081967 |
D43968 |
861 |
21q22.3 |
Hs.149261 Hs.612648 |
256 |
transcription factor activity protein binding ATP binding nucleus nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity positive regulation of granulocyte differentiation chloride ion binding positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter |
Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia |
227642_at |
0.937 |
4.545 |
3.418 |
3.751e-03 |
0.317 |
-1.722 |
TFCP2L1 |
transcription factor CP2-like 1 |
2 |
-121690635 |
AI928242 |
29842 |
2q14 |
Hs.156471 |
8 |
negative regulation of transcription from RNA polymerase II promoter cell morphogenesis epithelial cell maturation transcription factor activity transcription corepressor activity nucleus cytoplasm steroid biosynthetic process cytoplasm organization salivary gland development female pregnancy determination of adult lifespan membrane general transcriptional repressor activity regulation of transcription positive regulation of growth |
|
216627_s_at |
B4GALT1 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
9 |
-33100638 |
U10473 |
2683 |
9p13 |
Hs.272011 |
41 |
Golgi trans cisterna epithelial cell development acute inflammatory response beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity N-acetyllactosamine synthase activity lactose synthase activity extracellular region Golgi apparatus plasma membrane carbohydrate metabolic process lactose biosynthetic process galactose metabolic process protein amino acid terminal N-glycosylation cell adhesion binding of sperm to zona pellucida penetration of zona pellucida cytoskeletal protein binding negative regulation of cell proliferation glycoprotein biosynthetic process oligosaccharide biosynthetic process oligosaccharide biosynthetic process external side of plasma membrane integral to membrane basolateral plasma membrane transferase activity, transferring glycosyl groups desmosome glycocalyx manganese ion binding extracellular matrix organization mammary gland development brush border membrane development of secondary sexual characteristics metal ion binding branching morphogenesis of a tube leukocyte migration regulation of cell motion regulation of acrosome reaction positive regulation of epithelial cell proliferation involved in wound healing angiogenesis involved in wound healing positive regulation of apoptosis involved in mammary gland involution |
Galactose metabolism N-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
59697_at |
RAB15 |
RAB15, member RAS onocogene family |
14 |
-64482284 |
AA582932 |
376267 |
14q23.3 |
Hs.512492 |
11 |
nucleotide binding GTP binding plasma membrane small GTPase mediated signal transduction protein transport |
|
206863_x_at |
-0.343 |
4.521 |
-2.379 |
3.084e-02 |
0.542 |
-3.505 |
HRK |
harakiri, BCL2 interacting protein (contains only BH3 domain) |
12 |
-115783409 |
U76376 |
8739 |
12q24.22 |
Hs.87247 |
18 |
protein binding induction of apoptosis negative regulation of survival gene product expression regulation of apoptosis |
|
219036_at |
0.373 |
6.139 |
3.195 |
5.941e-03 |
0.357 |
-2.113 |
CEP70 |
centrosomal protein 70kDa |
3 |
-139695876 |
NM_024491 |
80321 |
3q22-q23 |
Hs.531962 |
9 |
protein binding centrosome |
|
212590_at |
0.627 |
7.834 |
3.111 |
7.051e-03 |
0.372 |
-2.259 |
RRAS2 |
related RAS viral (r-ras) oncogene homolog 2 |
11 |
-14256041, -14256041 |
AI431643 |
22800 |
11p15.2 |
Hs.502004 |
25 |
nucleotide binding GTPase activity protein binding GTP binding intracellular endoplasmic reticulum plasma membrane Ras protein signal transduction cellular process positive regulation of cell migration |
MAPK signaling pathway Tight junction Regulation of actin cytoskeleton |
200837_at |
0.393 |
8.040 |
2.746 |
1.487e-02 |
0.453 |
-2.892 |
BCAP31 |
B-cell receptor-associated protein 31 |
X |
-152619140, -152619140, -152619140, -152619140 |
NM_005745 |
10134 |
Xq28 |
Hs.522817 |
35 |
Golgi membrane receptor binding endoplasmic reticulum plasma membrane integral to plasma membrane intracellular protein transport apoptosis immune response vesicle-mediated transport |
|
211456_x_at |
1.064 |
10.327 |
5.008 |
1.496e-04 |
0.171 |
0.982 |
MT1P2 |
metallothionein 1 pseudogene 2 |
1 |
|
AF333388 |
645745 |
1q43 |
Hs.632513 |
1 |
|
|
209207_s_at |
0.512 |
6.153 |
3.450 |
3.509e-03 |
0.309 |
-1.665 |
SEC22B |
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) |
1 |
143807763 |
BC001364 |
9554 |
1q21.1 |
Hs.632438 Hs.715002 |
13 |
protein binding endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus ER to Golgi vesicle-mediated transport protein transport membrane integral to membrane vesicle-mediated transport melanosome |
SNARE interactions in vesicular transport |
214960_at |
0.360 |
5.476 |
2.547 |
2.216e-02 |
0.499 |
-3.228 |
API5 |
apoptosis inhibitor 5 |
11 |
43290080 |
AF229253 |
8539 |
11p11.2 |
Hs.435771 |
15 |
binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding |
|
221536_s_at |
LSG1 |
large subunit GTPase 1 homolog (S. cerevisiae) |
3 |
-195842806 |
AL136897 |
55341 |
3q29 |
Hs.518505 |
12 |
nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export |
|
237145_at |
0.514 |
2.934 |
4.561 |
3.621e-04 |
0.183 |
0.252 |
EIF2AK4 |
eukaryotic translation initiation factor 2 alpha kinase 4 |
15 |
38013638 |
AI953362 |
440275 |
15q15.1 |
Hs.656673 |
10 |
nucleotide binding eukaryotic translation initiation factor 2alpha kinase activity aminoacyl-tRNA ligase activity protein binding ATP binding intracellular cytoplasm tRNA aminoacylation for protein translation regulation of translational initiation protein amino acid phosphorylation transferase activity cytosolic ribosome |
|
219929_s_at |
ZFYVE21 |
zinc finger, FYVE domain containing 21 |
14 |
103251897 |
NM_024071 |
79038 |
14q32.33 |
Hs.592322 |
4 |
zinc ion binding metal ion binding |
|
223028_s_at |
SNX9 |
sorting nexin 9 |
6 |
158164281 |
BC005022 |
51429 |
6q25.1-q26 |
Hs.191213 |
24 |
protein binding cell communication protein transport phosphoinositide binding |
|
242738_s_at |
ZFHX3 |
zinc finger homeobox 3 |
16 |
-71374286 |
BG402859 |
463 |
16q22.3-q23.1 |
Hs.598297 |
26 |
negative regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription factor activity, enhancer binding intracellular nucleus transcription factor complex mitochondrion regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity sequence-specific DNA binding metal ion binding |
|
213744_at |
0.325 |
4.784 |
2.162 |
4.694e-02 |
0.583 |
-3.852 |
ATRNL1 |
attractin-like 1 |
10 |
116843113 |
AI817331 |
26033 |
10q26 |
Hs.501127 |
3 |
binding sugar binding membrane integral to membrane |
|
201736_s_at |
0.329 |
6.603 |
2.796 |
1.344e-02 |
0.437 |
-2.807 |
MARCH6 |
membrane-associated ring finger (C3HC4) 6 |
5 |
10406827 |
BF000409 |
10299 |
5p15.2 |
Hs.432862 |
8 |
endoplasmic reticulum zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding |
|
1558486_at |
ZNF493 |
zinc finger protein 493 |
19 |
21371760, 21371760 |
BC022394 |
284443 |
19p12 |
Hs.656558 |
3 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
215931_s_at |
0.272 |
3.413 |
2.180 |
4.539e-02 |
0.581 |
-3.824 |
ARFGEF2 |
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
20 |
46971681 |
AV657604 |
10564 |
20q13.13 |
Hs.62578 |
23 |
Golgi membrane ARF guanyl-nucleotide exchange factor activity binding intracellular cytosol exocytosis intracellular signaling cascade membrane myosin binding regulation of ARF protein signal transduction |
|
212266_s_at |
0.564 |
8.004 |
4.759 |
2.444e-04 |
0.172 |
0.578 |
SFRS5 |
splicing factor, arginine/serine-rich 5 |
14 |
69303581, 69303586 |
AW084582 |
6430 |
14q24 |
Hs.632326 |
28 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA splice site selection RNA splicing RS domain binding |
|
214370_at |
0.490 |
2.682 |
2.769 |
1.419e-02 |
0.446 |
-2.853 |
S100A8 |
S100 calcium binding protein A8 |
1 |
-151629131 |
AW238654 |
6279 |
1q21 |
Hs.416073 |
91 |
calcium ion binding protein binding inflammatory response |
|
228899_at |
0.499 |
5.092 |
3.098 |
7.246e-03 |
0.375 |
-2.282 |
LOC100132884 |
hypothetical protein LOC100132884 |
7 |
|
AI870903 |
100132884 |
7q36.1 |
Hs.535040 |
|
|
|
1554579_a_at |
MYO18B |
myosin XVIIIB |
22 |
24468119 |
AB042648 |
84700 |
22q11.2-q12.1 |
Hs.417959 |
11 |
nucleotide binding motor activity actin binding protein binding ATP binding nucleus cytoplasm unconventional myosin complex sarcomere |
|
40255_at |
0.351 |
6.337 |
3.428 |
3.669e-03 |
0.314 |
-1.703 |
DDX28 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
16 |
-66612674 |
AC004531 |
55794 |
16q22.1 |
Hs.458313 |
9 |
nucleotide binding RNA binding helicase activity ATP binding nucleus mitochondrion ATP-dependent helicase activity hydrolase activity mitochondrial nucleoid |
|
202815_s_at |
HEXIM1 |
hexamethylene bis-acetamide inducible 1 |
17 |
40580466 |
NM_006460 |
10614 |
17q21.31 |
Hs.586945 Hs.634944 Hs.716487 |
28 |
negative regulation of transcription from RNA polymerase II promoter cyclin-dependent protein kinase inhibitor activity protein binding nucleus cytoplasm heart development specific transcriptional repressor activity snRNA binding regulation of transcription negative regulation of cyclin-dependent protein kinase activity |
|
1553585_a_at |
MAGEA5 |
melanoma antigen family A, 5 |
X |
-151033181 |
NM_021049 |
4104 |
Xq28 |
Hs.668021 |
7 |
molecular_function cellular_component biological_process |
|
225861_at |
C16orf14 |
chromosome 16 open reading frame 14 |
16 |
631849 |
AW001250 |
84331 |
16p13.3 |
Hs.417710 |
5 |
protein binding |
|
1564224_x_at |
-0.312 |
4.679 |
-2.653 |
1.791e-02 |
0.475 |
-3.049 |
UNQ2963 |
hypothetical LOC283314 |
12 |
7152179 |
AK091792 |
283314 |
12p13.31 |
Hs.715709 |
2 |
|
|
236846_at |
-0.549 |
3.810 |
-2.620 |
1.913e-02 |
0.489 |
-3.105 |
LOC284757 |
hypothetical protein LOC284757 |
20 |
|
AI808031 |
284757 |
20q13.33 |
Hs.656468 |
1 |
|
|
242565_x_at |
C21orf57 |
chromosome 21 open reading frame 57 |
21 |
46530694, 46530694 |
AI146751 |
54059 |
21q22.3 |
Hs.474066 |
4 |
peptidase activity metallopeptidase activity zinc ion binding metal ion binding |
|
221235_s_at |
0.243 |
6.044 |
2.473 |
2.565e-02 |
0.517 |
-3.351 |
LOC644617 |
hypothetical LOC644617 |
2 |
|
NM_030825 |
644617 |
2q12.1 |
Hs.592796 |
1 |
|
|
229292_at |
0.288 |
4.599 |
2.700 |
1.630e-02 |
0.463 |
-2.970 |
EPB41L5 |
erythrocyte membrane protein band 4.1 like 5 |
2 |
120487138 |
AI652872 |
57669 |
2q14.2 |
Hs.654802 |
5 |
binding cytoplasm cytoskeleton adherens junction cytoskeletal protein binding extrinsic to membrane cell junction |
|
1553587_a_at |
0.412 |
7.607 |
2.207 |
4.306e-02 |
0.577 |
-3.781 |
POLE4 |
polymerase (DNA-directed), epsilon 4 (p12 subunit) |
2 |
75039282 |
NM_019896 |
56655 |
2p12 |
Hs.469060 |
5 |
DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding |
Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair |
225974_at |
1.014 |
6.270 |
2.698 |
1.638e-02 |
0.464 |
-2.974 |
TMEM64 |
transmembrane protein 64 |
8 |
-91703398 |
BF732480 |
169200 |
8q21.3 |
Hs.567759 |
2 |
membrane integral to membrane |
|
209717_at |
EVI5 |
ecotropic viral integration site 5 |
1 |
-92746840 |
AF008915 |
7813 |
1p22.1 |
Hs.594434 |
11 |
Rab GTPase activator activity protein binding intracellular nucleus centrosome cell cycle multicellular organismal development cell proliferation regulation of Rab GTPase activity cell division |
|
214556_at |
-0.334 |
5.077 |
-2.579 |
2.077e-02 |
0.497 |
-3.174 |
SSTR4 |
somatostatin receptor 4 |
20 |
22964056 |
NM_001052 |
6754 |
20p11.2 |
Hs.673846 |
29 |
receptor activity G-protein coupled receptor activity somatostatin receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger negative regulation of cell proliferation |
Neuroactive ligand-receptor interaction |
239218_at |
PDE1C |
phosphodiesterase 1C, calmodulin-dependent 70kDa |
7 |
-31795771 |
AI800515 |
5137 |
7p14.3 |
Hs.655694 |
10 |
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity |
Purine metabolism Calcium signaling pathway Olfactory transduction |
1553535_a_at |
0.302 |
5.713 |
2.337 |
3.351e-02 |
0.552 |
-3.574 |
RANGAP1 |
Ran GTPase activating protein 1 |
22 |
-39971560 |
NM_002883 |
5905 |
22q13 |
Hs.183800 |
34 |
condensed chromosome kinetochore GTPase activator activity Ran GTPase activator activity protein binding soluble fraction nucleus nuclear pore cytoplasm signal transduction membrane perinuclear region of cytoplasm |
|
233353_at |
-0.239 |
4.397 |
-2.131 |
4.979e-02 |
0.591 |
-3.900 |
FER1L5 |
fer-1-like 5 (C. elegans) |
2 |
96672300, 96724920 |
AL133022 |
90342 |
2q11.2 |
Hs.534025 |
2 |
membrane integral to membrane |
|
239012_at |
0.818 |
7.441 |
2.679 |
1.701e-02 |
0.469 |
-3.006 |
RNF144B |
ring finger protein 144B |
6 |
18495572 |
R83905 |
255488 |
6p22.3 |
Hs.148741 |
6 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding apoptosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding |
|
209791_at |
0.750 |
10.070 |
3.501 |
3.160e-03 |
0.304 |
-1.576 |
PADI2 |
peptidyl arginine deiminase, type II |
1 |
-17265842 |
AL049569 |
11240 |
1p36.13 |
Hs.33455 |
20 |
protein-arginine deiminase activity calcium ion binding cytoplasm protein modification process hydrolase activity peptidyl-citrulline biosynthetic process from peptidyl-arginine |
|
218678_at |
1.166 |
7.924 |
3.477 |
3.318e-03 |
0.308 |
-1.618 |
NES |
nestin |
1 |
-154905179 |
NM_024609 |
10763 |
1q23.1 |
Hs.527971 |
87 |
structural molecule activity cytoskeleton intermediate filament central nervous system development |
|
1569129_s_at |
C3orf38 |
chromosome 3 open reading frame 38 |
3 |
88281582 |
BC016013 |
285237 |
3p11.1 |
Hs.476944 Hs.518099 |
2 |
apoptosis |
|
214771_x_at |
MPRIP |
myosin phosphatase Rho interacting protein |
17 |
16886831, 16886831 |
AK025604 |
23164 |
17p11.2 |
Hs.462341 |
16 |
actin binding protein binding cytoplasm cytoskeleton |
|
208072_s_at |
0.368 |
8.209 |
2.237 |
4.069e-02 |
0.570 |
-3.734 |
DGKD |
diacylglycerol kinase, delta 130kDa |
2 |
233927891, 233961538 |
NM_003648 |
8527 |
2q37.1 |
Hs.471675 |
14 |
nucleotide binding diacylglycerol kinase activity ATP binding cytoplasm plasma membrane epidermal growth factor receptor signaling pathway activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway multicellular organismal development zinc ion binding response to organic substance cytoplasmic membrane-bounded vesicle cell growth transferase activity second-messenger-mediated signaling diacylglycerol binding protein homodimerization activity diacylglycerol metabolic process metal ion binding protein heterodimerization activity protein homooligomerization |
Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways Phosphatidylinositol signaling system |
208743_s_at |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide |
20 |
42947757 |
BC001359 |
7529 |
20q13.1 |
Hs.643544 |
109 |
cytoplasm cytosol protein targeting Ras protein signal transduction activation of pro-apoptotic gene products enzyme binding protein domain specific binding negative regulation of protein amino acid dephosphorylation melanosome positive regulation of catalytic activity perinuclear region of cytoplasm |
Cell cycle Neurotrophin signaling pathway |
226673_at |
SH2D3C |
SH2 domain containing 3C |
9 |
-129540416, -129540416, -129540416, -129540416, -129540416, -129540416 |
AW665063 |
10044 |
9q34.11 |
Hs.306412 |
16 |
SH3/SH2 adaptor activity guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm JNK cascade small GTPase mediated signal transduction membrane |
|
210971_s_at |
ARNTL |
aryl hydrocarbon receptor nuclear translocator-like |
11 |
13255900 |
AB000815 |
406 |
11p15 |
Hs.65734 |
37 |
transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction circadian rhythm aryl hydrocarbon receptor binding positive regulation of transcription from RNA polymerase II promoter Hsp90 protein binding |
Circadian rhythm - mammal |
207382_at |
0.772 |
8.137 |
3.692 |
2.131e-03 |
0.276 |
-1.241 |
TP63 |
tumor protein p63 |
3 |
190831909, 190831909, 190990142, 190990142 |
NM_003722 |
8626 |
3q28 |
Hs.137569 |
238 |
response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization |
|
241634_at |
-0.402 |
4.202 |
-3.045 |
8.073e-03 |
0.387 |
-2.374 |
LOC100132345 |
hypothetical LOC100132345 |
3 |
|
BE669595 |
100132345 |
3p24.3 |
|
|
|
|
1569879_a_at |
-0.327 |
6.234 |
-3.608 |
2.534e-03 |
0.287 |
-1.388 |
MEGF11 |
multiple EGF-like-domains 11 |
15 |
-63974687 |
BC029999 |
84465 |
15q22.31 |
Hs.712886 |
6 |
plasma membrane integral to membrane |
|
211197_s_at |
-0.288 |
5.329 |
-3.362 |
4.208e-03 |
0.325 |
-1.820 |
ICOSLG |
inducible T-cell co-stimulator ligand |
21 |
-44471149 |
AL355690 |
23308 |
21q22.3 |
Hs.14155 |
29 |
receptor binding defense response immune response hyperosmotic response signal transduction membrane integral to membrane positive regulation of activated T cell proliferation T cell activation B cell activation |
Cell adhesion molecules (CAMs) |
225677_at |
BCAP29 |
B-cell receptor-associated protein 29 |
7 |
107007657, 107008439 |
AW152589 |
55973 |
7q22-q31 |
Hs.303787 |
12 |
endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport |
|
1569034_a_at |
-0.217 |
2.968 |
-2.386 |
3.047e-02 |
0.541 |
-3.495 |
LOC440864 |
hypothetical gene supported by BC040724 |
2 |
|
BC019620 |
440864 |
2p16.3 |
Hs.388171 |
1 |
|
|
212616_at |
CHD9 |
chromodomain helicase DNA binding protein 9 |
16 |
51646445 |
BF668950 |
80205 |
16q12.2 |
Hs.59159 Hs.622347 |
10 |
nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription |
|
235033_at |
NPEPL1 |
aminopeptidase-like 1 |
20 |
56701267 |
AL577823 |
79716 |
20q13.32 |
Hs.554211 Hs.654868 |
7 |
aminopeptidase activity intracellular proteolysis peptidase activity zinc ion binding manganese ion binding metal ion binding |
|
224445_s_at |
ZFYVE21 |
zinc finger, FYVE domain containing 21 |
14 |
103251897 |
BC005999 |
79038 |
14q32.33 |
Hs.592322 |
4 |
zinc ion binding metal ion binding |
|
220944_at |
PGLYRP4 |
peptidoglycan recognition protein 4 |
1 |
-151569220 |
NM_020393 |
57115 |
1q21 |
Hs.58356 |
5 |
protein binding intracellular N-acetylmuramoyl-L-alanine amidase activity peptidoglycan catabolic process peptidoglycan receptor activity membrane detection of bacterium innate immune response defense response to Gram-positive bacterium |
|
226678_at |
UNC13D |
unc-13 homolog D (C. elegans) |
17 |
-71334901 |
BG054744 |
201294 |
17q25.1 |
Hs.41045 |
21 |
granuloma formation germinal center formation cytoplasm exocytosis phagocytosis membrane natural killer cell degranulation defense response to virus |
|
205113_at |
0.731 |
2.959 |
3.871 |
1.474e-03 |
0.250 |
-0.928 |
NEFM |
neurofilament, medium polypeptide |
8 |
24827178, 24828359 |
NM_005382 |
4741 |
8p21 |
Hs.458657 Hs.615287 |
24 |
microtubule cytoskeleton organization structural constituent of cytoskeleton cytoskeleton neurofilament axon cargo transport axon regulation of axon diameter neuromuscular junction intermediate filament bundle assembly neurofilament cytoskeleton organization |
Amyotrophic lateral sclerosis (ALS) |
222633_at |
0.394 |
8.550 |
3.499 |
3.173e-03 |
0.305 |
-1.580 |
TBL1XR1 |
transducin (beta)-like 1 X-linked receptor 1 |
3 |
-178221235 |
AF268193 |
79718 |
3q26.32 |
Hs.715537 |
14 |
nucleus chromatin modification modification-dependent protein catabolic process regulation of transcription |
Wnt signaling pathway |
204723_at |
1.046 |
5.615 |
3.216 |
5.687e-03 |
0.356 |
-2.076 |
SCN3B |
sodium channel, voltage-gated, type III, beta |
11 |
-123005104 |
AB032984 |
55800 |
11q23.3 |
Hs.4865 |
19 |
voltage-gated ion channel activity voltage-gated sodium channel activity plasma membrane ion transport sodium ion transport integral to membrane sodium ion binding |
|
210206_s_at |
DDX11 |
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae) |
12 |
31118045 |
U33833 |
1663 |
12p11 |
Hs.443960 |
13 |
mitotic sister chromatid segregation S phase of mitotic cell cycle G2/M transition of mitotic cell cycle nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP binding nucleus nucleolus nucleobase, nucleoside, nucleotide and nucleic acid metabolic process cell cycle positive regulation of cell proliferation hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
|
237252_at |
THBD |
thrombomodulin |
20 |
-22974269 |
AW119113 |
7056 |
20p11.2 |
Hs.2030 |
133 |
transmembrane receptor activity calcium ion binding protein binding extracellular space plasma membrane plasma membrane integral to plasma membrane female pregnancy blood coagulation embryonic development response to X-ray response to lipopolysaccharide response to cAMP |
Complement and coagulation cascades |
216841_s_at |
SOD2 |
superoxide dismutase 2, mitochondrial |
6 |
-160022744, -160020138 |
X15132 |
6648 |
6q25.3 |
Hs.487046 |
354 |
response to superoxide age-dependent response to oxidative stress age-dependent response to reactive oxygen species release of cytochrome c from mitochondria liver development detection of oxygen vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure superoxide dismutase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix double-strand break repair regulation of transcription from RNA polymerase II promoter glutathione metabolic process mitochondrion organization heart development locomotory behavior regulation of blood pressure post-embryonic development organ senescence response to gamma radiation response to activity oxidoreductase activity removal of superoxide radicals respiratory electron transport chain hemopoiesis manganese ion binding oxygen homeostasis response to hydrogen peroxide superoxide anion generation negative regulation of neuron apoptosis positive regulation of nitric oxide biosynthetic process negative regulation of fat cell differentiation metal ion binding negative regulation of fibroblast proliferation neuron development response to axon injury erythrophore differentiation regulation of catalytic activity protein homotetramerization regulation of mitochondrial membrane potential iron ion homeostasis response to hyperoxia oxidation reduction |
Huntington's disease |
211744_s_at |
CD58 |
CD58 molecule |
1 |
-116862845, -116858679 |
BC005930 |
965 |
1p13 |
Hs.34341 |
38 |
protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane |
Cell adhesion molecules (CAMs) |
217817_at |
0.340 |
7.266 |
3.927 |
1.313e-03 |
0.243 |
-0.831 |
ARPC4 |
actin related protein 2/3 complex, subunit 4, 20kDa |
3 |
9809226 |
BE891920 |
10093 |
3p25.3 |
Hs.323342 |
16 |
cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding |
Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
204759_at |
0.703 |
6.766 |
2.891 |
1.106e-02 |
0.425 |
-2.642 |
RCBTB2 |
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
13 |
-47961099 |
NM_001268 |
1102 |
13q14.3 |
Hs.657385 |
8 |
Ran guanyl-nucleotide exchange factor activity protein binding |
|
221207_s_at |
-0.417 |
6.864 |
-2.488 |
2.489e-02 |
0.513 |
-3.326 |
NBEA |
neurobeachin |
13 |
34414455 |
NM_015678 |
26960 |
13q13 |
Hs.491172 |
11 |
protein binding cytoplasm trans-Golgi network cytosol plasma membrane protein localization endomembrane system protein kinase binding |
|
238889_at |
0.411 |
2.954 |
3.506 |
3.125e-03 |
0.304 |
-1.567 |
AGBL5 |
ATP/GTP binding protein-like 5 |
2 |
27127994, 27127994 |
AA045527 |
60509 |
2p23.3 |
Hs.138207 |
4 |
metallocarboxypeptidase activity nucleus cytoplasm proteolysis zinc ion binding |
|
202606_s_at |
0.380 |
7.210 |
2.854 |
1.194e-02 |
0.426 |
-2.706 |
TLK1 |
tousled-like kinase 1 |
2 |
-171555578, -171555578, -171555578 |
NM_012290 |
9874 |
2q31.1 |
Hs.719163 |
23 |
nucleotide binding regulation of chromatin assembly or disassembly protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus protein amino acid phosphorylation intracellular protein transport response to DNA damage stimulus cell cycle intracellular signaling cascade chromatin modification transferase activity |
|
211549_s_at |
0.468 |
3.008 |
4.075 |
9.691e-04 |
0.223 |
-0.574 |
HPGD |
hydroxyprostaglandin dehydrogenase 15-(NAD) |
4 |
-175647902, -175647902 |
U63296 |
3248 |
4q34-q35 |
Hs.596913 |
47 |
prostaglandin E receptor activity binding nucleus nucleolus cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy parturition 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity lipoxygenase pathway protein homodimerization activity negative regulation of cell cycle NAD or NADH binding oxidation reduction |
|
214792_x_at |
-0.534 |
5.584 |
-3.400 |
3.892e-03 |
0.319 |
-1.753 |
VAMP2 |
vesicle-associated membrane protein 2 (synaptobrevin 2) |
17 |
-8003189 |
AI955119 |
6844 |
17p13.1 |
Hs.25348 |
66 |
protein binding integral to plasma membrane membrane vesicle-mediated transport synaptosome cell junction cytoplasmic vesicle synapse |
SNARE interactions in vesicular transport |
224739_at |
-0.481 |
7.857 |
-2.272 |
3.799e-02 |
0.565 |
-3.678 |
PIM3 |
pim-3 oncogene |
22 |
48740146 |
BE778706 |
415116 |
22q13 |
Hs.530381 |
10 |
nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity |
|
228930_at |
0.445 |
6.512 |
2.443 |
2.725e-02 |
0.526 |
-3.401 |
SCARNA15 |
small Cajal body-specific RNA 15 |
15 |
81221750 |
AI679611 |
677778 |
15q25.2 |
Hs.513091 |
1 |
|
|
223538_at |
0.419 |
7.560 |
2.147 |
4.828e-02 |
0.589 |
-3.875 |
SERF1A |
small EDRK-rich factor 1A (telomeric) |
5 |
69356827, 69356827, 70232245, 70232245, -510079, -499652 |
AF073518 |
8293 |
5q12.2-q13.3 |
Hs.559428 |
7 |
|
|
233314_at |
PTEN |
phosphatase and tensin homolog |
10 |
89613174 |
AK021487 |
5728 |
10q23.3 |
Hs.500466 |
557 |
regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade |
Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer |
201796_s_at |
VARS |
valyl-tRNA synthetase |
6 |
-31853275, -3191374, -3006978 |
BE790854 |
7407 |
6p21.3 |
Hs.520026 |
15 |
nucleotide binding valine-tRNA ligase activity protein binding ATP binding intracellular cytoplasm mitochondrion cytosol translational elongation valyl-tRNA aminoacylation defense response response to unfolded protein response to nutrient ligase activity protein complex NF-kappaB binding |
Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis |
232395_x_at |
0.465 |
2.682 |
4.039 |
1.043e-03 |
0.225 |
-0.636 |
AGBL3 |
ATP/GTP binding protein-like 3 |
7 |
134321798 |
AI674787 |
340351 |
7q33 |
Hs.648616 |
4 |
metallocarboxypeptidase activity cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding |
|
223466_x_at |
COL4A3BP |
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
5 |
-74702683, -74702683 |
BC000102 |
10087 |
5q13.3 |
Hs.270437 |
26 |
protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response |
|
1564063_a_at |
-0.376 |
5.207 |
-3.741 |
1.924e-03 |
0.273 |
-1.154 |
ATP11B |
ATPase, class VI, type 11B |
3 |
183993984 |
AK093727 |
23200 |
3q27 |
Hs.478429 |
8 |
nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding nuclear inner membrane ATP biosynthetic process ion transport metabolic process ion transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport aminophospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
|
212667_at |
0.604 |
9.178 |
3.151 |
6.500e-03 |
0.364 |
-2.190 |
SPARC |
secreted protein, acidic, cysteine-rich (osteonectin) |
5 |
-151021201 |
AL575922 |
6678 |
5q31.3-q32 |
Hs.111779 Hs.708558 |
115 |
ossification copper ion binding calcium ion binding collagen binding extracellular region extracellular region basement membrane signal transduction platelet alpha granule lumen regulation of cell proliferation extracellular matrix binding |
|
218077_s_at |
0.353 |
5.205 |
2.374 |
3.118e-02 |
0.543 |
-3.514 |
ZDHHC3 |
zinc finger, DHHC-type containing 3 |
3 |
-44931757 |
BE542551 |
51304 |
3p21.31 |
Hs.61430 |
8 |
Golgi apparatus zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding |
|
218906_x_at |
KLC2 |
kinesin light chain 2 |
11 |
65781340, 65781666, 65781749, 65781749 |
NM_022822 |
64837 |
11q13.2 |
Hs.280792 |
22 |
microtubule motor activity protein binding cytosol kinesin complex microtubule protein complex |
|
1560974_s_at |
NOS1 |
nitric oxide synthase 1 (neuronal) |
12 |
-116135361 |
BF447723 |
4842 |
12q24.2-q24.31 |
Hs.654410 |
188 |
response to hypoxia photoreceptor inner segment nitric-oxide synthase activity calmodulin binding cytoplasm cytoskeleton arginine catabolic process nitric oxide biosynthetic process myoblast fusion electron carrier activity response to heat FMN binding negative regulation of calcium ion transport into cytosol oxidoreductase activity sarcoplasmic reticulum heme binding multicellular organismal response to stress tetrahydrobiopterin binding arginine binding neurotransmitter biosynthetic process sarcolemma cell projection dendritic spine positive regulation of vasodilation positive regulation of vasodilation cadmium ion binding metal ion binding perinuclear region of cytoplasm FAD binding NADP or NADPH binding oxidation reduction regulation of cardiac muscle contraction |
Arginine and proline metabolism Metabolic pathways Calcium signaling pathway Long-term depression Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer Small cell lung cancer |
201245_s_at |
0.382 |
7.079 |
2.852 |
1.199e-02 |
0.426 |
-2.710 |
OTUB1 |
OTU domain, ubiquitin aldehyde binding 1 |
11 |
63509900 |
AL523776 |
55611 |
11q13.1 |
Hs.473788 |
15 |
immune response peptidase activity cysteine-type peptidase activity modification-dependent protein catabolic process |
|
223294_at |
0.352 |
7.370 |
2.209 |
4.289e-02 |
0.576 |
-3.778 |
CXorf26 |
chromosome X open reading frame 26 |
X |
75309172 |
BC001220 |
51260 |
Xq13.3 |
Hs.370100 |
6 |
molecular_function cellular_component biological_process |
|
213875_x_at |
0.446 |
6.283 |
2.515 |
2.362e-02 |
0.508 |
-3.282 |
C6orf62 |
chromosome 6 open reading frame 62 |
6 |
-24813069 |
BG252842 |
81688 |
6p22.3 |
Hs.519930 |
6 |
molecular_function cellular_component intracellular biological_process |
|
1552651_a_at |
0.413 |
3.771 |
3.477 |
3.316e-03 |
0.308 |
-1.617 |
RFFL |
ring finger and FYVE-like domain containing 1 |
17 |
-30360243, -30360243 |
AK093112 |
117584 |
17q12 |
Hs.13680 |
11 |
protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding |
|
201573_s_at |
ETF1 |
eukaryotic translation termination factor 1 |
5 |
-137869682 |
M75715 |
2107 |
5q31.1 |
Hs.483494 |
32 |
RNA binding protein binding cytoplasm regulation of translational termination protein amino acid methylation translation release factor activity, codon specific ribosome binding |
|
204394_at |
SLC43A1 |
solute carrier family 43, member 1 |
11 |
-57008582 |
NM_003627 |
8501 |
11p11.2-p11.1 |
Hs.591952 |
8 |
integral to plasma membrane transport neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity neutral amino acid transport L-amino acid transport membrane |
|
232355_at |
SNORD114-3 |
small nucleolar RNA, C/D box 114-3 |
14 |
100489438 |
AU146318 |
767579 |
14q32 |
Hs.613596 |
2 |
|
|
216779_at |
-0.173 |
3.685 |
-2.327 |
3.417e-02 |
0.553 |
-3.590 |
CYLC1 |
cylicin, basic protein of sperm head cytoskeleton 1 |
X |
83002825 |
Z22780 |
1538 |
Xq21.1 |
Hs.444230 |
6 |
structural molecule activity cytoplasm cytoskeleton multicellular organismal development spermatogenesis cell differentiation cytoskeletal calyx acrosomal matrix |
|
228375_at |
1.315 |
5.406 |
4.604 |
3.321e-04 |
0.179 |
0.324 |
IGSF11 |
immunoglobulin superfamily, member 11 |
3 |
-120102168, -120102168 |
BE221674 |
152404 |
3q13.32 |
Hs.112873 |
7 |
receptor activity protein binding plasma membrane cell adhesion integral to membrane regulation of growth |
|
224454_at |
ETNK1 |
ethanolamine kinase 1 |
12 |
22669342, 22669342 |
BC006111 |
55500 |
12p12.1 |
Hs.29464 |
4 |
nucleotide binding ethanolamine kinase activity ATP binding cytoplasm phosphatidylethanolamine biosynthetic process transferase activity |
Glycerophospholipid metabolism Metabolic pathways |
202638_s_at |
ICAM1 |
intercellular adhesion molecule 1 |
19 |
10242516 |
NM_000201 |
3383 |
19p13.3-p13.2 |
Hs.643447 |
541 |
immunological synapse regulation of leukocyte mediated cytotoxicity T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell T cell antigen processing and presentation positive regulation of cellular extravasation transmembrane receptor activity integrin binding protein binding extracellular space cytoplasm plasma membrane plasma membrane integral to plasma membrane heterophilic cell adhesion leukocyte adhesion external side of plasma membrane membrane to membrane docking regulation of cell adhesion cell adhesion mediated by integrin interspecies interaction between organisms virion attachment, binding of host cell surface receptor leukocyte migration adhesion to symbiont |
Cell adhesion molecules (CAMs) Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration |
235104_at |
0.714 |
4.216 |
3.158 |
6.402e-03 |
0.364 |
-2.177 |
ERAP2 |
endoplasmic reticulum aminopeptidase 2 |
5 |
96237399 |
BG292389 |
64167 |
5q15 |
Hs.482910 |
14 |
aminopeptidase activity endoplasmic reticulum endoplasmic reticulum lumen proteolysis immune response regulation of blood pressure peptidase activity metallopeptidase activity zinc ion binding membrane integral to membrane antigen processing and presentation of endogenous peptide antigen via MHC class I metal ion binding |
|
228403_at |
-0.268 |
5.692 |
-2.235 |
4.084e-02 |
0.570 |
-3.737 |
ENHO |
energy homeostasis associated |
9 |
-34511039 |
AL541276 |
375704 |
9p13.3 |
Hs.522085 |
3 |
extracellular region |
|
219269_at |
-1.917 |
6.784 |
-4.524 |
3.898e-04 |
0.192 |
0.190 |
HMBOX1 |
homeobox containing 1 |
8 |
28803829, 28804143 |
NM_024567 |
79618 |
8p21.1 |
Hs.591836 |
5 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
212197_x_at |
0.289 |
8.775 |
2.447 |
2.699e-02 |
0.525 |
-3.393 |
MPRIP |
myosin phosphatase Rho interacting protein |
17 |
16886831, 16886831 |
AB020671 |
23164 |
17p11.2 |
Hs.462341 |
16 |
actin binding protein binding cytoplasm cytoskeleton |
|
202122_s_at |
PLIN3 |
perilipin 3 |
19 |
-4789345 |
NM_005817 |
10226 |
19p13.3 |
Hs.140452 |
35 |
protein binding cytoplasm endosome Golgi apparatus lipid particle membrane vesicle-mediated transport |
|
226342_at |
SPTBN1 |
spectrin, beta, non-erythrocytic 1 |
2 |
54536957, 54639034 |
AW593244 |
6711 |
2p21 |
Hs.503178 Hs.705692 |
46 |
actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping |
|
205289_at |
BMP2 |
bone morphogenetic protein 2 |
20 |
6696744 |
AA583044 |
650 |
20p12 |
Hs.73853 |
195 |
branching involved in ureteric bud morphogenesis cytokine activity extracellular region extracellular region extracellular space inflammatory response cell-cell signaling growth factor activity negative regulation of cell proliferation embryonic development organ morphogenesis positive regulation of pathway-restricted SMAD protein phosphorylation specific transcriptional repressor activity positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway negative regulation of gene-specific transcription cardiac cell differentiation growth odontogenesis of dentine-containing tooth cell fate commitment positive regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter SMAD binding positive regulation of astrocyte differentiation cartilage development cardiac epithelial to mesenchymal transition |
Cytokine-cytokine receptor interaction Hedgehog signaling pathway TGF-beta signaling pathway Pathways in cancer Basal cell carcinoma |
1554631_at |
-0.288 |
5.793 |
-2.759 |
1.448e-02 |
0.447 |
-2.869 |
ATM |
ataxia telangiectasia mutated |
11 |
107598768, 107663328 |
BC007023 |
472 |
11q22-q23 |
Hs.367437 |
504 |
nucleotide binding DNA binding protein serine/threonine kinase activity ATP binding nucleus nucleoplasm DNA repair response to DNA damage stimulus cell cycle mitotic cell cycle spindle assembly checkpoint reciprocal meiotic recombination signal transduction cell death response to ionizing radiation 1-phosphatidylinositol-3-kinase activity transferase activity cytoplasmic vesicle protein N-terminus binding |
Cell cycle p53 signaling pathway Apoptosis |
208741_at |
SAP18 |
Sin3A-associated protein, 18kDa |
13 |
20612652 |
AW274856 |
10284 |
13q12.11 |
Hs.524899 |
17 |
histone deacetylase complex transcription corepressor activity protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter regulation of transcription |
|
228941_at |
ALG10B |
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast) |
12 |
36996823 |
AW295395 |
144245 |
12q12 |
Hs.259305 |
5 |
plasma membrane integral to membrane transferase activity, transferring hexosyl groups |
N-Glycan biosynthesis Metabolic pathways |
218368_s_at |
0.873 |
7.033 |
3.102 |
7.193e-03 |
0.374 |
-2.276 |
TNFRSF12A |
tumor necrosis factor receptor superfamily, member 12A |
16 |
3010313 |
NM_016639 |
51330 |
16p13.3 |
Hs.355899 |
25 |
angiogenesis ruffle receptor activity protein binding plasma membrane apoptosis cell motion substrate-bound cell migration, cell attachment to substrate cell adhesion multicellular organismal development cell death cell surface integral to membrane cell differentiation positive regulation of axon extension |
Cytokine-cytokine receptor interaction |
1564029_at |
-0.368 |
2.763 |
-3.700 |
2.092e-03 |
0.276 |
-1.226 |
USP49 |
ubiquitin specific peptidase 49 |
6 |
-41873360 |
AL049937 |
25862 |
6p21 |
Hs.665742 |
5 |
ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding |
|
212882_at |
KLHL18 |
kelch-like 18 (Drosophila) |
3 |
47299333 |
AB018338 |
23276 |
3p21.31 |
Hs.517946 |
8 |
protein binding |
|
221905_at |
CYLD |
cylindromatosis (turban tumor syndrome) |
16 |
49333461, 49333529 |
BF516433 |
1540 |
16q12.1 |
Hs.578973 |
54 |
structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm |
RIG-I-like receptor signaling pathway |
1553447_at |
AGBL1 |
ATP/GTP binding protein-like 1 |
15 |
84486245 |
NM_152336 |
123624 |
15q25.3 |
Hs.679833 |
5 |
metallocarboxypeptidase activity binding cytoplasm proteolysis peptidase activity metallopeptidase activity zinc ion binding metal ion binding |
|
228126_x_at |
-0.218 |
4.605 |
-2.375 |
3.111e-02 |
0.543 |
-3.512 |
CTXN1 |
cortexin 1 |
19 |
-7895380 |
BF982289 |
404217 |
19p13.2 |
Hs.657978 |
3 |
membrane integral to membrane |
|
238738_at |
PSMD7 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
16 |
72888181 |
AW361702 |
5713 |
16q23-q24 |
Hs.440604 |
47 |
proteasome complex protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
224088_at |
NMUR2 |
neuromedin U receptor 2 |
5 |
-151751294 |
AF272363 |
56923 |
5q33.1 |
Hs.283093 |
10 |
neuromedin U receptor activity reduction of food intake in response to dietary excess receptor activity G-protein coupled receptor activity intracellular calcium activated chloride channel activity GTP binding plasma membrane calcium ion transport regulation of smooth muscle contraction signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration neuropeptide signaling pathway cell-cell signaling central nervous system development grooming behavior feeding behavior integral to membrane transmission of nerve impulse activation of phospholipase A2 activity by calcium-mediated signaling inositol phosphate-mediated signaling response to pain arachidonic acid secretion response to protein stimulus |
Neuroactive ligand-receptor interaction |
220610_s_at |
LRRFIP2 |
leucine rich repeat (in FLII) interacting protein 2 |
3 |
-37069120 |
NM_006309 |
9209 |
3p22.2 |
Hs.719246 |
7 |
protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding |
|
222443_s_at |
0.547 |
7.690 |
3.838 |
1.576e-03 |
0.257 |
-0.985 |
RBM8A |
RNA binding motif protein 8A |
1 |
144218994 |
AF182415 |
9939 |
1q12 |
Hs.356873 |
43 |
nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport |
|
214853_s_at |
0.325 |
8.396 |
3.113 |
7.033e-03 |
0.372 |
-2.257 |
SHC1 |
SHC (Src homology 2 domain containing) transforming protein 1 |
1 |
-153201397, -153201397 |
AI091079 |
6464 |
1q21 |
Hs.433795 |
255 |
activation of MAPK activity transmembrane receptor protein tyrosine kinase adaptor protein activity epidermal growth factor receptor binding insulin receptor binding insulin-like growth factor receptor binding protein binding phospholipid binding cytoplasm mitochondrion cytosol plasma membrane epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor activity intracellular signaling cascade Ras protein signal transduction positive regulation of cell proliferation insulin receptor signaling pathway regulation of growth positive regulation of DNA replication Shc-EGFR complex |
ErbB signaling pathway Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity Neurotrophin signaling pathway Insulin signaling pathway Glioma Chronic myeloid leukemia |
227702_at |
CYP4X1 |
cytochrome P450, family 4, subfamily X, polypeptide 1 |
1 |
47261826 |
AA557324 |
260293 |
1p33 |
Hs.439760 |
7 |
monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity |
|
230700_at |
RTN4RL1 |
reticulon 4 receptor-like 1 |
17 |
-1784720 |
H06251 |
146760 |
17p13.3 |
Hs.22917 |
5 |
receptor activity protein binding plasma membrane axon regeneration anchored to plasma membrane |
|
205503_at |
PTPN14 |
protein tyrosine phosphatase, non-receptor type 14 |
1 |
-212597633 |
NM_005401 |
5784 |
1q32.2 |
Hs.696573 |
13 |
protein tyrosine phosphatase activity binding cytoplasm cytoskeleton protein amino acid dephosphorylation hydrolase activity |
|
214636_at |
1.922 |
2.674 |
3.123 |
6.888e-03 |
0.370 |
-2.239 |
CALCB |
calcitonin-related polypeptide beta |
11 |
15051721 |
AA747379 |
797 |
11p15.2-p15.1 |
Hs.534305 |
15 |
neuropeptide hormone activity extracellular region soluble fraction cellular calcium ion homeostasis signal transduction vasodilation |
|
1555870_at |
RNF207 |
ring finger protein 207 |
1 |
6188775 |
AK056658 |
388591 |
1p36.31 |
Hs.716549 |
7 |
protein binding intracellular zinc ion binding metal ion binding |
|
204647_at |
0.684 |
8.045 |
2.436 |
2.757e-02 |
0.526 |
-3.411 |
HOMER3 |
homer homolog 3 (Drosophila) |
19 |
-18901009, -18901009, -18901009, -18901009, -18901009 |
NM_004838 |
9454 |
19p13.11 |
Hs.10326 |
16 |
protein binding cytoplasm plasma membrane protein targeting metabotropic glutamate receptor signaling pathway postsynaptic density cell junction synapse postsynaptic membrane |
|
225341_at |
0.549 |
6.223 |
3.631 |
2.416e-03 |
0.284 |
-1.348 |
MTERFD3 |
MTERF domain containing 3 |
12 |
-105895198 |
BF697312 |
80298 |
12q24.1 |
Hs.5009 |
6 |
mitochondrion transcription termination regulation of transcription |
|
223698_at |
SLC25A36 |
solute carrier family 25, member 36 |
3 |
142143351 |
AL136803 |
55186 |
3q23 |
Hs.144130 |
7 |
transporter activity binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane response to estradiol stimulus |
|
226360_at |
ZNRF3 |
zinc and ring finger 3 |
22 |
27609889 |
AK022809 |
84133 |
22q12.1 |
Hs.655242 |
8 |
protein binding zinc ion binding membrane integral to membrane metal ion binding |
|
1564658_at |
C7orf52 |
chromosome 7 open reading frame 52 |
7 |
-100600497 |
BC037583 |
375607 |
7q22.1 |
Hs.213044 |
2 |
N-acetyltransferase activity metabolic process acyltransferase activity transferase activity |
|
210764_s_at |
1.706 |
5.000 |
3.236 |
5.453e-03 |
0.352 |
-2.041 |
CYR61 |
cysteine-rich, angiogenic inducer, 61 |
1 |
85819031 |
AF003114 |
3491 |
1p31-p22 |
Hs.8867 |
82 |
regulation of cell growth patterning of blood vessels insulin-like growth factor binding extracellular region chemotaxis cell adhesion heparin binding cell proliferation anatomical structure morphogenesis positive regulation of cell-substrate adhesion extracellular matrix organization extracellular matrix binding |
|
210896_s_at |
0.542 |
5.196 |
3.535 |
2.945e-03 |
0.298 |
-1.516 |
ASPH |
aspartate beta-hydroxylase |
8 |
-62739837, -62699648, -62699648, -62575669 |
AF306765 |
444 |
8q12.1 |
Hs.591874 |
24 |
peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis |
|
215826_x_at |
ZNF835 |
zinc finger protein 835 |
19 |
-61866764 |
AK023017 |
90485 |
19q13.43 |
Hs.458438 |
1 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
228178_s_at |
CHTF8 |
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) |
16 |
-67709413, -67709413 |
AI739514 |
54921 |
16q22.1 |
Hs.85962 |
9 |
DNA binding nucleus DNA replication cell cycle |
|
208866_at |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
BF510713 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
235463_s_at |
LASS6 |
LAG1 homolog, ceramide synthase 6 |
2 |
169021080 |
AI081356 |
253782 |
2q24.3 |
Hs.506829 Hs.718403 |
5 |
transcription factor activity nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding ceramide biosynthetic process sphingosine N-acyltransferase activity |
|
239084_at |
SNAP29 |
synaptosomal-associated protein, 29kDa |
22 |
19543291 |
BE896490 |
9342 |
22q11.21 |
Hs.108002 Hs.701035 |
19 |
SNAP receptor activity cytoplasm plasma membrane exocytosis vesicle targeting membrane fusion protein transport synaptosome cell junction synapse |
SNARE interactions in vesicular transport |
1552610_a_at |
JAK1 |
Janus kinase 1 |
1 |
-65071493 |
NM_002227 |
3716 |
1p32.3-p31.3 |
Hs.207538 |
118 |
nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity growth hormone receptor binding protein binding ATP binding nucleus cytoplasm cytoskeleton enzyme linked receptor protein signaling pathway protein kinase cascade membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway response to antibiotic |
Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer |
212567_s_at |
MAP4 |
microtubule-associated protein 4 |
3 |
-47989573, -47867183, -47867183 |
AL523310 |
4134 |
3p21 |
Hs.517949 |
40 |
structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
210540_s_at |
0.493 |
3.874 |
2.567 |
2.129e-02 |
0.497 |
-3.195 |
B4GALT4 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
3 |
-120413278 |
BC004523 |
8702 |
3q13.3 |
Hs.13225 |
14 |
N-acetyllactosamine synthase activity Golgi apparatus carbohydrate metabolic process membrane lipid metabolic process galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding metal ion binding |
Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
232636_at |
1.981 |
4.987 |
3.038 |
8.194e-03 |
0.387 |
-2.387 |
SLITRK4 |
SLIT and NTRK-like family, member 4 |
X |
-142543607 |
AL080239 |
139065 |
Xq27.3 |
Hs.272284 |
4 |
protein binding axonogenesis membrane integral to membrane |
|
209226_s_at |
0.353 |
7.806 |
3.137 |
6.684e-03 |
0.367 |
-2.214 |
TNPO1 |
transportin 1 |
5 |
72148173, 72179685 |
U72069 |
3842 |
5q13.2 |
Hs.482497 |
58 |
protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
215265_at |
EMX1 |
empty spiracles homeobox 1 |
2 |
72998111 |
BF515060 |
2016 |
2p14-p13 |
Hs.516090 |
9 |
transcription factor activity nucleus regulation of transcription, DNA-dependent brain development post-embryonic development cerebral cortex development neuron differentiation response to drug sequence-specific DNA binding |
|
208322_s_at |
0.480 |
7.144 |
3.258 |
5.218e-03 |
0.348 |
-2.003 |
ST3GAL1 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
8 |
-134536272 |
NM_003033 |
6482 |
8q24.22 |
Hs.374257 |
20 |
beta-galactoside alpha-2,3-sialyltransferase activity extracellular region Golgi apparatus protein amino acid glycosylation membrane integral to membrane integral to Golgi membrane |
O-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways |
236657_at |
LOC100130506 |
hypothetical protein LOC100130506 |
2 |
|
AW014647 |
100130506 |
|
|
|
|
|
207005_s_at |
BCL2 |
B-cell CLL/lymphoma 2 |
18 |
-59136166, -58941558 |
NM_000657 |
596 |
18q21.3 18q21.33 |
Hs.150749 |
705 |
G1/S transition of mitotic cell cycle protein phosphatase type 2A complex cell morphogenesis response to acid ovarian follicle development ureteric bud development branching involved in ureteric bud morphogenesis behavioral fear response response to hypoxia B cell homeostasis release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development renal system process intracellular membrane fraction nucleus cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum membrane microsome cytosol calcineurin complex protein amino acid dephosphorylation melanin metabolic process oxygen and reactive oxygen species metabolic process regulation of nitrogen utilization anti-apoptosis humoral immune response response to oxidative stress actin filament organization female pregnancy cell aging response to nutrient transcription factor binding cell death positive regulation of cell proliferation male gonad development activation of pro-apoptotic gene products response to radiation response to heat response to external stimulus response to toxin post-embryonic development organ morphogenesis response to inorganic substance response to iron ion response to UV-B response to gamma radiation regulation of gene expression negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration membrane integral to membrane cell-cell adhesion transcription activator activity peptidyl-threonine phosphorylation cochlear nucleus development gland morphogenesis hemopoiesis negative regulation of ossification negative regulation of cell growth negative regulation of cell migration response to caffeine hair follicle morphogenesis axon regeneration regulation of protein stability nuclear membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization negative regulation of myeloid cell apoptosis T cell differentiation in the thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine stimulus response to nicotine organ growth positive regulation of multicellular organism growth B cell proliferation response to drug response to hydrogen peroxide protein homodimerization activity T cell homeostasis positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment response to peptide hormone stimulus regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis ear development response to estrogen stimulus regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability protein heterodimerization activity focal adhesion formation positive regulation of pigmentation during development spleen development thymus development gut morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue response to glucocorticoid stimulus BH3 domain binding defense response to virus regulation of cell cycle response to protein stimulus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization regulation of calcium ion transport apoptosis in response to endoplasmic reticulum stress |
Apoptosis Focal adhesion Neurotrophin signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Colorectal cancer Prostate cancer Small cell lung cancer |
226606_s_at |
-1.072 |
6.176 |
-4.016 |
1.094e-03 |
0.227 |
-0.676 |
GTPBP5 |
GTP binding protein 5 (putative) |
20 |
60191475 |
AI860690 |
26164 |
20q13.33 |
Hs.340636 |
6 |
nucleotide binding GTP binding intracellular mitochondrion ribosome biogenesis |
|
212711_at |
CAMSAP1 |
calmodulin regulated spectrin-associated protein 1 |
9 |
-137840153 |
AA019977 |
157922 |
9q34.3 |
Hs.522493 |
2 |
|
|
213753_x_at |
0.615 |
8.952 |
3.444 |
3.556e-03 |
0.312 |
-1.676 |
EIF5A |
eukaryotic translation initiation factor 5A |
17 |
7151041, 7151579, 7152011, 7152417 |
BF541557 |
1984 |
17p13-p12 |
Hs.534314 |
52 |
RNA binding translation initiation factor activity translation elongation factor activity nucleus annulate lamellae nuclear pore cytoplasm endoplasmic reticulum cytosol mRNA export from nucleus translation translational frameshifting protein export from nucleus nucleocytoplasmic transport nucleocytoplasmic transport induction of apoptosis cell proliferation peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine protein transport membrane U6 snRNA binding viral genome replication ribosome binding positive regulation of translational elongation positive regulation of translational termination positive regulation of translational initiation protein N-terminus binding intracellular protein transmembrane transport |
|
238171_at |
-0.349 |
4.024 |
-3.115 |
6.998e-03 |
0.371 |
-2.253 |
SLC25A30 |
solute carrier family 25, member 30 |
13 |
-44865455 |
AI128486 |
253512 |
13q14.13 |
Hs.591230 |
3 |
binding mitochondrion mitochondrial inner membrane transport mitochondrial transport membrane integral to membrane |
|
224621_at |
MAPK1 |
mitogen-activated protein kinase 1 |
22 |
-20453318, -20443946 |
AA129773 |
5594 |
22q11.2 22q11.21 |
Hs.431850 |
822 |
MAPKKK cascade nucleotide binding phosphotyrosine binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol cytoskeleton protein amino acid phosphorylation induction of apoptosis chemotaxis response to DNA damage stimulus cell cycle Ras protein signal transduction synaptic transmission organ morphogenesis transferase activity MAP kinase 2 activity cytosine metabolic process lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to exogenous dsRNA interspecies interaction between organisms negative regulation of cell differentiation T cell receptor signaling pathway B cell receptor signaling pathway |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Dorso-ventral axis formation TGF-beta signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Gap junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Type II diabetes mellitus Alzheimer's disease Prion diseases Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
237005_at |
LOC442075 |
hypothetical LOC442075 |
3 |
|
AI923935 |
442075 |
3p25.3 |
Hs.666816 |
2 |
|
|
225363_at |
0.483 |
8.593 |
5.248 |
9.395e-05 |
0.162 |
1.362 |
PTEN |
phosphatase and tensin homolog |
10 |
89613174 |
AK024986 |
5728 |
10q23.3 |
Hs.500466 |
557 |
regulation of cyclin-dependent protein kinase activity magnesium ion binding angiogenesis phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding nucleus cytoplasm cytoplasm cytosol protein amino acid dephosphorylation protein amino acid dephosphorylation lipid metabolic process induction of apoptosis central nervous system development protein tyrosine/serine/threonine phosphatase activity negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity hydrolase activity PDZ domain binding negative regulation of cell migration neuron projection development regulation of protein stability negative regulation of apoptosis endothelial cell migration inositol phosphate dephosphorylation phosphoinositide dephosphorylation platelet-derived growth factor receptor signaling pathway cardiac muscle tissue development inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade |
Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Pathways in cancer Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer |
239208_s_at |
C21orf57 |
chromosome 21 open reading frame 57 |
21 |
46530694, 46530694 |
AW945538 |
54059 |
21q22.3 |
Hs.474066 |
4 |
peptidase activity metallopeptidase activity zinc ion binding metal ion binding |
|
217071_s_at |
MTHFR |
5,10-methylenetetrahydrofolate reductase (NADPH) |
1 |
-11768373 |
AJ249275 |
4524 |
1p36.3 |
Hs.214142 |
1776 |
methylenetetrahydrofolate reductase (NADPH) activity methylenetetrahydrofolate reductase (NADPH) activity protein binding cytosol cellular amino acid metabolic process methionine metabolic process blood circulation oxidoreductase activity oxidation reduction |
One carbon pool by folate Methane metabolism Metabolic pathways |
234464_s_at |
0.475 |
4.366 |
3.790 |
1.739e-03 |
0.267 |
-1.069 |
EME1 |
essential meiotic endonuclease 1 homolog 1 (S. pombe) |
17 |
45805588 |
AK021607 |
146956 |
17q21.33 |
Hs.514330 |
15 |
magnesium ion binding DNA binding endonuclease activity protein binding nucleus nucleolus DNA repair DNA recombination response to DNA damage stimulus hydrolase activity |
Homologous recombination |
218091_at |
AGFG1 |
ArfGAP with FG repeats 1 |
2 |
228045131 |
AI989512 |
3267 |
2q36.3 |
Hs.352962 |
29 |
DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding |
|
205112_at |
0.844 |
4.586 |
3.261 |
5.180e-03 |
0.347 |
-1.997 |
PLCE1 |
phospholipase C, epsilon 1 |
10 |
95743735 |
NM_016341 |
51196 |
10q23 |
Hs.655033 |
35 |
Golgi membrane activation of MAPK activity regulation of cell growth phosphoinositide phospholipase C activity receptor signaling protein activity guanyl-nucleotide exchange factor activity calcium ion binding intracellular membrane fraction cytoplasm Golgi apparatus cytosol plasma membrane phospholipid metabolic process diacylglycerol biosynthetic process regulation of smooth muscle contraction cytoskeleton organization epidermal growth factor receptor signaling pathway activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway heart development regulation of G-protein coupled receptor protein signaling pathway cell proliferation lipid catabolic process hydrolase activity Ras GTPase binding calcium-mediated signaling calcium-mediated signaling enzyme binding glomerulus development regulation of protein kinase activity regulation of Ras protein signal transduction inositol phosphate-mediated signaling |
Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system |
223309_x_at |
0.333 |
7.849 |
2.547 |
2.216e-02 |
0.499 |
-3.228 |
PNPLA8 |
patatin-like phospholipase domain containing 8 |
7 |
-107899306 |
BG025248 |
50640 |
7q31 |
Hs.617340 |
13 |
lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm |
|
237354_at |
-0.257 |
3.038 |
-2.572 |
2.109e-02 |
0.497 |
-3.187 |
PDXDC1 |
pyridoxal-dependent decarboxylase domain containing 1 |
16 |
14976333 |
N70298 |
23042 |
16p13.11 |
Hs.370781 |
6 |
protein binding lyase activity carboxy-lyase activity carboxylic acid metabolic process pyridoxal phosphate binding |
|
230098_at |
PHF20L1 |
PHD finger protein 20-like 1 |
8 |
133856785, 133856785, 133856785 |
AW612407 |
51105 |
8q24.22 |
Hs.304362 |
4 |
nucleic acid binding protein binding zinc ion binding metal ion binding |
|
1562511_at |
LYST |
lysosomal trafficking regulator |
1 |
-233890968 |
AL833100 |
1130 |
1q42.1-q42.2 |
Hs.532411 |
23 |
protein binding cytoplasm protein transport microtubule cytoskeleton leukocyte chemotaxis melanosome organization endosome to lysosome transport via multivesicular body sorting pathway mast cell secretory granule organization natural killer cell mediated cytotoxicity defense response to bacterium defense response to protozoan pigmentation defense response to virus |
|
210228_at |
CSF2 |
colony stimulating factor 2 (granulocyte-macrophage) |
5 |
131437383 |
M11734 |
1437 |
5q31.1 |
Hs.1349 |
172 |
cytokine activity granulocyte macrophage colony-stimulating factor receptor binding protein binding extracellular region extracellular space immune response positive regulation of cell proliferation positive regulation of foam cell differentiation positive regulation of tyrosine phosphorylation of Stat5 protein myeloid dendritic cell differentiation negative regulation of apoptosis positive regulation of DNA replication positive regulation of survival gene product expression negative regulation of cytolysis |
Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway |
202722_s_at |
0.724 |
6.119 |
3.103 |
7.171e-03 |
0.374 |
-2.274 |
GFPT1 |
glutamine-fructose-6-phosphate transaminase 1 |
2 |
-69400408 |
NM_002056 |
2673 |
2p13 |
Hs.580300 |
29 |
glutamine-fructose-6-phosphate transaminase (isomerizing) activity sugar binding cytoplasm fructose 6-phosphate metabolic process energy reserve metabolic process glutamine metabolic process metabolic process carbohydrate biosynthetic process transferase activity |
Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways |
200740_s_at |
0.257 |
9.325 |
2.452 |
2.672e-02 |
0.523 |
-3.385 |
SUMO3 |
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) |
21 |
-45049959 |
NM_006936 |
6612 |
21q22.3 |
Hs.474005 |
40 |
kinetochore protein binding cytoplasm protein sumoylation modification-dependent protein catabolic process |
|
240570_at |
0.569 |
2.731 |
2.563 |
2.145e-02 |
0.497 |
-3.201 |
INADL |
InaD-like (Drosophila) |
1 |
61980736 |
AW006782 |
10207 |
1p31.3 |
Hs.478125 |
24 |
protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction |
Tight junction |
236656_s_at |
LOC100130506 |
hypothetical protein LOC100130506 |
2 |
|
AW014647 |
100130506 |
|
|
|
|
|
233916_at |
0.481 |
3.388 |
3.481 |
3.293e-03 |
0.308 |
-1.611 |
KIAA1486 |
KIAA1486 |
2 |
225973845 |
AB040919 |
57624 |
2q36.3 |
Hs.224409 |
4 |
|
|
1564713_a_at |
-0.215 |
5.384 |
-2.248 |
3.981e-02 |
0.568 |
-3.716 |
FOXN4 |
forkhead box N4 |
12 |
-108200165 |
AF425597 |
121643 |
12q24.11 |
Hs.528316 |
6 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
223982_s_at |
0.275 |
8.445 |
2.363 |
3.186e-02 |
0.544 |
-3.532 |
PNPLA8 |
patatin-like phospholipase domain containing 8 |
7 |
-107899306 |
AB041261 |
50640 |
7q31 |
Hs.617340 |
13 |
lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm |
|
202948_at |
0.419 |
5.509 |
2.262 |
3.879e-02 |
0.567 |
-3.695 |
IL1R1 |
interleukin 1 receptor, type I |
2 |
102136833 |
NM_000877 |
3554 |
2q12 |
Hs.701982 |
160 |
transmembrane receptor activity interleukin-1, Type I, activating receptor activity platelet-derived growth factor receptor binding protein binding integral to plasma membrane cell surface receptor linked signal transduction membrane innate immune response interleukin-1-mediated signaling pathway response to interleukin-1 |
MAPK signaling pathway Cytokine-cytokine receptor interaction Apoptosis Hematopoietic cell lineage |
202644_s_at |
TNFAIP3 |
tumor necrosis factor, alpha-induced protein 3 |
6 |
138230273 |
NM_006290 |
7128 |
6q23 |
Hs.211600 |
80 |
DNA binding protein binding nucleus cytoplasm centrosome apoptosis anti-apoptosis peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process negative regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding |
|
1556209_at |
0.880 |
4.095 |
2.595 |
2.012e-02 |
0.491 |
-3.147 |
CLEC2B |
C-type lectin domain family 2, member B |
12 |
-9896234 |
CA447397 |
9976 |
12p13-p12 |
Hs.85201 |
10 |
binding sugar binding integral to plasma membrane membrane |
|
204089_x_at |
MAP3K4 |
mitogen-activated protein kinase kinase kinase 4 |
6 |
161332811 |
NM_006724 |
4216 |
6q26 |
Hs.390428 |
20 |
nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity ATP binding response to stress JNK cascade transferase activity |
MAPK signaling pathway GnRH signaling pathway |
213519_s_at |
0.768 |
6.327 |
5.259 |
9.203e-05 |
0.162 |
1.379 |
LAMA2 |
laminin, alpha 2 |
6 |
129245978 |
AI078169 |
3908 |
6q22-q23 |
Hs.200841 |
40 |
receptor binding structural molecule activity extracellular region basal lamina laminin-1 complex muscle organ development regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission, cholinergic sarcolemma regulation of embryonic development |
Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
209512_at |
HSDL2 |
hydroxysteroid dehydrogenase like 2 |
9 |
114182171 |
BC004331 |
84263 |
9q32 |
Hs.59486 |
6 |
binding sterol carrier activity oxidoreductase activity oxidation reduction |
|
204791_at |
NR2C1 |
nuclear receptor subfamily 2, group C, member 1 |
12 |
-93948315, -93938188 |
NM_003297 |
7181 |
12q22 |
Hs.108301 Hs.707524 |
17 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent zinc ion binding transcription repressor activity protein homodimerization activity histone deacetylase binding sequence-specific DNA binding metal ion binding |
|
214732_at |
-0.269 |
3.587 |
-2.132 |
4.969e-02 |
0.591 |
-3.899 |
SP1 |
Sp1 transcription factor |
12 |
52060245, 52060694 |
AU121035 |
6667 |
12q13.1 |
Hs.620754 Hs.649191 |
477 |
ossification trophectodermal cell differentiation liver development embryonic placenta development double-stranded DNA binding transcription factor activity RNA polymerase II transcription factor activity intracellular nucleus nucleolus cytoplasm protein C-terminus binding zinc ion binding transcription activator activity megakaryocyte differentiation lung development protein homodimerization activity histone deacetylase binding enucleate erythrocyte differentiation sequence-specific DNA binding interspecies interaction between organisms positive regulation of transcription from RNA polymerase II promoter, global metal ion binding embryonic camera-type eye morphogenesis embryonic skeletal system development embryonic process involved in female pregnancy definitive hemopoiesis |
TGF-beta signaling pathway Huntington's disease |
214005_at |
0.397 |
7.333 |
2.933 |
1.015e-02 |
0.416 |
-2.569 |
GGCX |
gamma-glutamyl carboxylase |
2 |
-85629703 |
BE326952 |
2677 |
2p12 |
Hs.77719 |
53 |
membrane fraction endoplasmic reticulum protein modification process blood coagulation gamma-glutamyl carboxylase activity membrane integral to membrane ligase activity peptidyl-glutamic acid carboxylation |
|
242835_s_at |
0.340 |
5.308 |
2.269 |
3.824e-02 |
0.565 |
-3.683 |
LOC728730 |
hypothetical LOC728730 |
2 |
|
AW772084 |
728730 |
2p22.1 |
|
|
|
|
239147_at |
-0.266 |
5.756 |
-2.488 |
2.489e-02 |
0.513 |
-3.326 |
ARSK |
arylsulfatase family, member K |
5 |
94916580 |
AI243677 |
153642 |
5q15 |
Hs.585051 |
5 |
arylsulfatase activity calcium ion binding extracellular region metabolic process hydrolase activity |
|
228921_at |
-0.355 |
4.254 |
-2.786 |
1.370e-02 |
0.440 |
-2.823 |
SLC25A42 |
solute carrier family 25, member 42 |
19 |
19035807 |
AW170609 |
284439 |
19p13.11 |
Hs.303669 |
3 |
binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
217234_s_at |
0.375 |
4.581 |
2.661 |
1.764e-02 |
0.473 |
-3.036 |
EZR |
ezrin |
6 |
-159106760, -159106760 |
AF199015 |
7430 |
6q25.2-q26 |
Hs.487027 |
158 |
ruffle cytoplasm cytosol actin filament plasma membrane microvillus cell cortex cytoskeletal anchoring at plasma membrane leukocyte adhesion cytoskeletal protein binding regulation of cell shape extrinsic to membrane membrane to membrane docking filopodium cortical cytoskeleton apical part of cell cell adhesion molecule binding actin filament binding actin filament bundle formation |
Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC |
202352_s_at |
0.391 |
8.329 |
3.437 |
3.603e-03 |
0.314 |
-1.688 |
PSMD12 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
17 |
-62767081, -62767080 |
AI446530 |
5718 |
17q24.2 |
Hs.646575 |
39 |
protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
219343_at |
0.795 |
8.355 |
2.780 |
1.386e-02 |
0.442 |
-2.833 |
CDC37L1 |
cell division cycle 37 homolog (S. cerevisiae)-like 1 |
9 |
4669565 |
NM_017913 |
55664 |
9p24.1 |
Hs.561954 |
6 |
protein binding cytoplasm |
|
224961_at |
SCYL2 |
SCY1-like 2 (S. cerevisiae) |
12 |
99185679 |
AB037781 |
55681 |
12q23.1 |
Hs.506481 |
8 |
protein kinase activity binding ATP binding cytoplasm endosome Golgi apparatus protein amino acid phosphorylation endosome membrane membrane clathrin-coated vesicle cytoplasmic vesicle perinuclear region of cytoplasm |
|
218103_at |
0.325 |
7.369 |
2.625 |
1.897e-02 |
0.488 |
-3.098 |
FTSJ3 |
FtsJ homolog 3 (E. coli) |
17 |
-59250524 |
NM_017647 |
117246 |
17q23.3 |
Hs.463785 |
10 |
nucleic acid binding nucleus nucleolus rRNA processing methyltransferase activity transferase activity rRNA methylation methylation |
|
210175_at |
C2orf3 |
chromosome 2 open reading frame 3 |
2 |
-75742801 |
BC000853 |
6936 |
2p11.2-p11.1 |
Hs.303808 Hs.662279 |
13 |
transcription factor activity protein binding nucleus regulation of transcription |
|
226268_at |
RAB21 |
RAB21, member RAS oncogene family |
12 |
70434924 |
AI309554 |
23011 |
12q21.1 |
Hs.524590 |
12 |
Golgi membrane nucleotide binding protein binding GTP binding endosome endoplasmic reticulum Golgi apparatus small GTPase mediated signal transduction protein transport membrane cytoplasmic vesicle membrane cytoplasmic vesicle early endosome membrane |
|
226183_at |
0.244 |
6.525 |
2.136 |
4.934e-02 |
0.590 |
-3.893 |
GSK3B |
glycogen synthase kinase 3 beta |
3 |
-121023493 |
AW139538 |
2932 |
3q13.3 |
Hs.445733 Hs.593022 |
373 |
nucleotide binding re-entry into mitotic cell cycle p53 binding glycogen synthase kinase 3 activity ATP binding nucleus cytoplasm cytosol cytosol glycogen metabolic process anti-apoptosis response to stress ER overload response intracellular signaling cascade beta-catenin binding organ morphogenesis transferase activity peptidyl-serine phosphorylation growth cone beta-catenin destruction complex positive regulation of protein complex assembly protein kinase A catalytic subunit binding Axin-APC-beta-catenin-GSK3B complex cell soma dendritic shaft membrane-bounded organelle fat cell differentiation positive regulation of protein export from nucleus tau-protein kinase activity NF-kappaB binding Wnt receptor signaling pathway through beta-catenin |
ErbB signaling pathway Chemokine signaling pathway Cell cycle Wnt signaling pathway Hedgehog signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway B cell receptor signaling pathway Neurotrophin signaling pathway Insulin signaling pathway Melanogenesis Alzheimer's disease Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Basal cell carcinoma |
226528_at |
0.498 |
7.599 |
2.843 |
1.222e-02 |
0.427 |
-2.726 |
MTX3 |
metaxin 3 |
5 |
-79308294 |
AI743044 |
345778 |
5q14.1 |
Hs.531418 |
3 |
mitochondrion mitochondrial outer membrane protein targeting to mitochondrion protein transport membrane |
|
1556182_x_at |
hCG_20426 |
hypothetical protein LOC441869 |
1 |
-1343664 |
BC018095 |
441869 |
1p36.33 |
Hs.381222 |
3 |
|
|
236728_at |
1.198 |
4.987 |
4.272 |
6.491e-04 |
0.211 |
-0.236 |
LNPEP |
leucyl/cystinyl aminopeptidase |
5 |
96297101, 96319911 |
AW070437 |
4012 |
5q15 |
Hs.527199 Hs.656905 |
44 |
aminopeptidase activity extracellular region intracellular plasma membrane integral to plasma membrane proteolysis cell-cell signaling female pregnancy peptidase activity metallopeptidase activity zinc ion binding metal ion binding |
Renin-angiotensin system |
228986_at |
0.924 |
3.773 |
3.717 |
2.021e-03 |
0.273 |
-1.196 |
OSBPL8 |
oxysterol binding protein-like 8 |
12 |
-75269708 |
AW978375 |
114882 |
12q14 |
Hs.430849 |
13 |
lipid transport steroid metabolic process |
|
221284_s_at |
SRC |
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
20 |
35406501, 35407970 |
NM_005417 |
6714 |
20q12-q13 |
Hs.195659 |
589 |
nucleotide binding response to acid non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity ATP binding cytosol plasma membrane plasma membrane caveola response to stress signal complex assembly epidermal growth factor receptor signaling pathway protein kinase cascade Ras protein signal transduction protein C-terminus binding cell proliferation cell-cell adhesion cell migration transferase activity peptidyl-tyrosine phosphorylation forebrain development SH2 domain binding positive regulation of apoptosis interspecies interaction between organisms transcytosis positive regulation of cell adhesion positive regulation of insulin receptor signaling pathway platelet-derived growth factor receptor signaling pathway nerve growth factor receptor signaling pathway response to mineralocorticoid stimulus |
ErbB signaling pathway Endocytosis VEGF signaling pathway Focal adhesion Adherens junction Tight junction Gap junction GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection |
221468_at |
XCR1 |
chemokine (C motif) receptor 1 |
3 |
-46037294 |
NM_005283 |
2829 |
3p21.3 3p21.3-p21.1 |
Hs.248116 |
13 |
receptor activity G-protein coupled receptor activity chemokine receptor activity plasma membrane integral to plasma membrane chemotaxis inflammatory response signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger elevation of cytosolic calcium ion concentration response to cytokine stimulus release of sequestered calcium ion into cytosol |
Cytokine-cytokine receptor interaction Chemokine signaling pathway |
218869_at |
-0.646 |
8.408 |
-2.613 |
1.940e-02 |
0.489 |
-3.117 |
MLYCD |
malonyl-CoA decarboxylase |
16 |
82490230 |
NM_012213 |
23417 |
16q24 |
Hs.644610 |
16 |
methylmalonyl-CoA decarboxylase activity cytoplasm mitochondrion peroxisome cytosol acetyl-CoA biosynthetic process fatty acid biosynthetic process acyl-CoA metabolic process lyase activity regulation of fatty acid beta-oxidation malonyl-CoA decarboxylase activity |
beta-Alanine metabolism Propanoate metabolism Metabolic pathways |
200694_s_at |
DDX24 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 |
14 |
-93587020 |
NM_020414 |
57062 |
14q32 |
Hs.510328 |
20 |
nucleotide binding RNA binding ATP-dependent RNA helicase activity ATP binding cellular_component nucleolus cytoplasm RNA metabolic process hydrolase activity |
|
226254_s_at |
0.387 |
7.197 |
2.684 |
1.685e-02 |
0.467 |
-2.998 |
KIAA1430 |
KIAA1430 |
4 |
-186317812 |
AI912523 |
57587 |
4q35.1 |
Hs.535734 |
3 |
|
|
212003_at |
0.216 |
6.891 |
2.146 |
4.842e-02 |
0.589 |
-3.877 |
C1orf144 |
chromosome 1 open reading frame 144 |
1 |
16566169 |
BG171020 |
26099 |
1p36.13 |
Hs.252967 |
2 |
|
|
211672_s_at |
0.488 |
6.332 |
2.839 |
1.230e-02 |
0.427 |
-2.731 |
ARPC4 |
actin related protein 2/3 complex, subunit 4, 20kDa |
3 |
9809226 |
AF019888 |
10093 |
3p25.3 |
Hs.323342 |
16 |
cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding |
Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
207188_at |
-0.255 |
5.404 |
-2.277 |
3.762e-02 |
0.564 |
-3.669 |
CDK3 |
cyclin-dependent kinase 3 |
17 |
71508581 |
NM_001258 |
1018 |
17q22-qter |
Hs.706766 |
21 |
nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding protein amino acid phosphorylation cell cycle mitosis cell proliferation transferase activity cell division |
|
229092_at |
0.313 |
5.750 |
2.284 |
3.715e-02 |
0.562 |
-3.659 |
NR2F2 |
nuclear receptor subfamily 2, group F, member 2 |
15 |
94670160, 94675114, 94676797, 94677572 |
AI420144 |
7026 |
15q26 |
Hs.657455 |
27 |
transcription factor activity ligand-regulated transcription factor activity steroid hormone receptor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter lipid metabolic process signal transduction zinc ion binding sequence-specific DNA binding metal ion binding |
|
204560_at |
1.179 |
4.975 |
4.831 |
2.118e-04 |
0.172 |
0.696 |
FKBP5 |
FK506 binding protein 5 |
6 |
-35656311, -35649339, -35649339, -35649339 |
NM_004117 |
2289 |
6p21.3-p21.2 |
Hs.407190 |
50 |
peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding |
|
211968_s_at |
0.418 |
9.335 |
2.234 |
4.092e-02 |
0.570 |
-3.739 |
HSP90AA1 |
heat shock protein 90kDa alpha (cytosolic), class A member 1 |
14 |
-101616827, -101616827 |
AI962933 |
3320 |
14q32.33 |
Hs.525600 Hs.700831 |
275 |
nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly |
Antigen processing and presentation Pathways in cancer Prostate cancer |
217542_at |
0.315 |
4.898 |
2.768 |
1.421e-02 |
0.446 |
-2.854 |
MDM2 |
Mdm2 p53 binding protein homolog (mouse) |
12 |
67488237, 67489063 |
BE930512 |
4193 |
12q14.3-q15 |
Hs.484551 |
555 |
negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding |
Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia |
201032_at |
0.511 |
9.957 |
3.080 |
7.523e-03 |
0.376 |
-2.314 |
BLCAP |
bladder cancer associated protein |
20 |
-35579232 |
NM_006698 |
10904 |
20q11.2-q12 |
Hs.472651 Hs.718404 |
9 |
membrane integral to membrane |
|
1552257_a_at |
0.321 |
5.887 |
3.325 |
4.538e-03 |
0.332 |
-1.884 |
TTLL12 |
tubulin tyrosine ligase-like family, member 12 |
22 |
-41892571 |
NM_015140 |
23170 |
22q13.31 |
Hs.517670 |
6 |
tubulin-tyrosine ligase activity protein modification process |
|
213100_at |
UNC5B |
unc-5 homolog B (C. elegans) |
10 |
72642303 |
AA127885 |
219699 |
10q22.1 |
Hs.522997 |
12 |
receptor activity protein binding apoptosis signal transduction multicellular organismal development membrane integral to membrane |
Axon guidance |
202012_s_at |
0.452 |
6.047 |
3.176 |
6.172e-03 |
0.361 |
-2.146 |
EXT2 |
exostoses (multiple) 2 |
11 |
44073674 |
AA196245 |
2132 |
11p12-p11 |
Hs.368404 |
55 |
ossification mesoderm formation protein binding endoplasmic reticulum Golgi apparatus glycosaminoglycan biosynthetic process signal transduction heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process membrane integral to membrane cell differentiation intrinsic to endoplasmic reticulum membrane heparan sulfate N-acetylglucosaminyltransferase activity protein homodimerization activity protein heterodimerization activity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
Heparan sulfate biosynthesis Metabolic pathways |
203000_at |
STMN2 |
stathmin-like 2 |
8 |
80685934 |
BF967657 |
11075 |
8q21.13 |
Hs.521651 |
23 |
protein binding membrane fraction soluble fraction cytoplasm intracellular signaling cascade membrane neuron differentiation axon growth cone cell projection perinuclear region of cytoplasm |
|
39582_at |
0.584 |
6.985 |
2.730 |
1.536e-02 |
0.457 |
-2.920 |
CYLD |
cylindromatosis (turban tumor syndrome) |
16 |
49333461, 49333529 |
AL050166 |
1540 |
16q12.1 |
Hs.578973 |
54 |
structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm |
RIG-I-like receptor signaling pathway |
1555439_at |
GTF3C3 |
general transcription factor IIIC, polypeptide 3, 102kDa |
2 |
-197337344 |
AF465407 |
9330 |
2q33.1 |
Hs.470996 |
10 |
transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity binding nucleus transcription, DNA-dependent 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter |
|
229302_at |
TMEM178 |
transmembrane protein 178 |
2 |
39746596 |
AA058832 |
130733 |
2p22.1 |
Hs.40808 |
3 |
membrane integral to membrane |
|
222815_at |
0.389 |
4.330 |
2.403 |
2.946e-02 |
0.536 |
-3.466 |
RLIM |
ring finger protein, LIM domain interacting |
X |
-73719537 |
BE966018 |
51132 |
Xq13-q21 |
Hs.653288 |
9 |
transcription corepressor activity ubiquitin-protein ligase activity protein binding zinc ion binding negative regulation of transcription ligase activity transcriptional repressor complex modification-dependent protein catabolic process metal ion binding |
|
210427_x_at |
1.098 |
9.499 |
4.440 |
4.615e-04 |
0.193 |
0.049 |
ANXA2 |
annexin A2 |
15 |
-58426642, -58426641 |
BC001388 |
302 |
15q21-q22 |
Hs.511605 |
137 |
skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm |
|
241199_x_at |
DPPA4 |
developmental pluripotency associated 4 |
3 |
-110527677 |
AV756594 |
55211 |
3q13.13 |
Hs.317659 |
8 |
protein binding nucleus |
|
243912_x_at |
APOBEC3F |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
22 |
37766618, 37766618 |
BF511268 |
200316 |
22q13.1 |
Hs.659809 |
51 |
positive regulation of defense response to virus by host RNA binding cytidine deaminase activity transcription, RNA-dependent zinc ion binding base conversion or substitution editing hydrolase activity apolipoprotein B mRNA editing enzyme complex innate immune response negative regulation of retroviral genome replication metal ion binding negative regulation of viral reproduction |
Atrazine degradation |
225557_at |
CSRNP1 |
cysteine-serine-rich nuclear protein 1 |
3 |
-39158347 |
AI091372 |
64651 |
3p22 |
Hs.370950 |
4 |
molecular_function transcription factor activity cellular_component nucleus apoptosis regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
|
201566_x_at |
ID2 |
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
2 |
8739563 |
D13891 |
3398 |
2p25 |
Hs.180919 |
76 |
negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleus cytoplasm multicellular organismal development heart development negative regulation of transcription transcription repressor activity enucleate erythrocyte differentiation negative regulation of transcription factor activity positive regulation of macrophage differentiation |
TGF-beta signaling pathway |
209183_s_at |
C10orf10 |
chromosome 10 open reading frame 10 |
10 |
-44791714 |
AL136653 |
11067 |
10q11.21 |
Hs.93675 |
14 |
mitochondrion |
|
228113_at |
-0.256 |
3.387 |
-2.714 |
1.585e-02 |
0.459 |
-2.946 |
RAB37 |
RAB37, member RAS oncogene family |
17 |
70178850, 70244553, 70244950 |
R62453 |
326624 |
17q25.1 |
Hs.592097 |
11 |
nucleotide binding GTP binding ER-Golgi intermediate compartment small GTPase mediated signal transduction protein transport cytoplasmic vesicle |
|
225521_at |
0.426 |
5.871 |
2.370 |
3.140e-02 |
0.543 |
-3.520 |
ANAPC7 |
anaphase promoting complex subunit 7 |
12 |
-109297656, -109295087 |
AL137586 |
51434 |
12q24.11 |
Hs.524741 |
30 |
binding nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
202440_s_at |
0.590 |
5.903 |
3.324 |
4.555e-03 |
0.332 |
-1.887 |
ST5 |
suppression of tumorigenicity 5 |
11 |
-8671474, -8671474, -8671474 |
NM_005418 |
6764 |
11p15 |
Hs.117715 |
11 |
protein binding |
|
226058_at |
B3GNT9 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 |
16 |
-65739505 |
AI651445 |
84752 |
16q22.1 |
Hs.718517 |
2 |
Golgi apparatus protein amino acid glycosylation galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups |
|
205852_at |
CDK5R2 |
cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
2 |
219532641 |
R51311 |
8941 |
2q35 |
Hs.158460 |
11 |
regulation of cyclin-dependent protein kinase activity cyclin-dependent protein kinase 5 activator complex cyclin-dependent protein kinase 5 activator activity |
|
209513_s_at |
HSDL2 |
hydroxysteroid dehydrogenase like 2 |
9 |
114182171 |
BC004331 |
84263 |
9q32 |
Hs.59486 |
6 |
binding sterol carrier activity oxidoreductase activity oxidation reduction |
|
208581_x_at |
1.315 |
10.736 |
4.885 |
1.903e-04 |
0.172 |
0.784 |
MT1X |
metallothionein 1X |
16 |
55273882 |
NM_005952 |
4501 |
16q13 |
Hs.374950 |
18 |
copper ion binding zinc ion binding response to metal ion cadmium ion binding metal ion binding |
|
224952_at |
0.454 |
4.534 |
3.576 |
2.704e-03 |
0.290 |
-1.444 |
TANC2 |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
17 |
58440629 |
BF115054 |
26115 |
17q23.2-q23.3 |
Hs.410889 |
3 |
binding |
|
212185_x_at |
1.151 |
10.784 |
4.508 |
4.030e-04 |
0.192 |
0.163 |
MT2A |
metallothionein 2A |
16 |
55199978 |
NM_005953 |
4502 |
16q13 |
Hs.647371 |
53 |
protein binding cellular copper ion homeostasis zinc ion binding metal ion binding |
|
224674_at |
-0.262 |
6.640 |
-2.617 |
1.926e-02 |
0.489 |
-3.110 |
TTYH3 |
tweety homolog 3 (Drosophila) |
7 |
2638128 |
AI934753 |
80727 |
7p22 |
Hs.440899 |
5 |
ion channel activity chloride channel activity calcium ion binding plasma membrane ion transport integral to membrane chloride ion binding chloride channel complex |
|
209149_s_at |
TM9SF1 |
transmembrane 9 superfamily member 1 |
14 |
-23729083, -23728192 |
BE899402 |
10548 |
14q11.2 |
Hs.91586 |
5 |
membrane integral to membrane |
|
1558675_s_at |
0.452 |
6.888 |
2.869 |
1.157e-02 |
0.426 |
-2.680 |
SDCCAG1 |
serologically defined colon cancer antigen 1 |
14 |
-49320281 |
AV724508 |
9147 |
14q22 |
Hs.655964 |
8 |
nucleus cytoplasm |
|
201037_at |
0.853 |
6.504 |
3.482 |
3.285e-03 |
0.308 |
-1.609 |
PFKP |
phosphofructokinase, platelet |
10 |
3099751 |
NM_002627 |
5214 |
10p15.3-p15.2 |
Hs.26010 |
24 |
nucleotide binding magnesium ion binding 6-phosphofructokinase activity 6-phosphofructokinase activity protein binding ATP binding cytoplasm cytosol cytosol 6-phosphofructokinase complex glycolysis kinase activity transferase activity |
Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Galactose metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
242996_at |
0.496 |
3.503 |
2.658 |
1.773e-02 |
0.473 |
-3.040 |
MTRF1 |
mitochondrial translational release factor 1 |
13 |
-40688515 |
AI341686 |
9617 |
13q14.1-q14.3 |
Hs.382176 |
8 |
cytoplasm mitochondrion regulation of translational termination translation release factor activity, codon specific |
|
208675_s_at |
0.305 |
8.268 |
2.463 |
2.617e-02 |
0.520 |
-3.368 |
DDOST |
dolichyl-diphosphooligosaccharide-protein glycosyltransferase |
1 |
-20850846 |
D29643 |
1650 |
1p36.1 |
Hs.523145 |
12 |
dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum microsome protein amino acid terminal N-glycosylation oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine response to cytokine stimulus T cell activation |
N-Glycan biosynthesis Metabolic pathways |
218648_at |
CRTC3 |
CREB regulated transcription coactivator 3 |
15 |
88874201 |
NM_022769 |
64784 |
15q26.1 |
Hs.567572 |
10 |
nucleus cytoplasm interspecies interaction between organisms regulation of transcription |
|
212460_at |
C14orf147 |
chromosome 14 open reading frame 147 |
14 |
-33971894 |
BE738425 |
171546 |
14q13.1 |
Hs.269909 |
5 |
serine C-palmitoyltransferase activity protein binding endoplasmic reticulum membrane integral to membrane serine C-palmitoyltransferase complex sphingolipid biosynthetic process |
|
220611_at |
-0.240 |
4.182 |
-2.411 |
2.901e-02 |
0.534 |
-3.454 |
DAB1 |
disabled homolog 1 (Drosophila) |
1 |
-57236166 |
NM_021080 |
1600 |
1p32-p31 |
Hs.477370 |
37 |
multicellular organismal development nervous system development cell differentiation |
|
236263_at |
SHH |
sonic hedgehog homolog (Drosophila) |
7 |
-155288318 |
AI192528 |
6469 |
7q36 |
Hs.164537 |
144 |
patterning of blood vessels vasculogenesis metanephros development branching involved in ureteric bud morphogenesis cell fate specification neural crest cell migration neural tube formation positive regulation of neuroblast proliferation positive regulation of mesenchymal cell proliferation osteoblast development patched binding protein binding extracellular region extracellular space plasma membrane signal transduction positive regulation of hh target transcription factor activity cell-cell signaling pattern specification process axon guidance ventral midline development open tracheal system development salivary gland morphogenesis hindgut morphogenesis heart development blood coagulation androgen metabolic process peptidase activity anterior/posterior pattern formation cell surface oligodendrocyte development intein-mediated protein splicing spinal cord dorsal/ventral patterning dorsal/ventral neural tube patterning smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation positive regulation of granule cell precursor proliferation telencephalon regionalization regulation of proteolysis lung development negative regulation of cell migration male genitalia development prostate gland development regulation of epithelial cell differentiation forebrain development midbrain development hindbrain development hair follicle morphogenesis negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of T cell proliferation negative regulation of protein catabolic process positive regulation of protein import into nucleus odontogenesis of dentine-containing tooth embryonic digit morphogenesis camera-type eye development laminin-1 binding tongue morphogenesis membrane raft myoblast differentiation regulation of transcription negative regulation of cell differentiation positive regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter negative regulation of alpha-beta T cell differentiation digestive tract morphogenesis embryonic organ development developmental growth neuron fate commitment response to axon injury embryonic skeletal system development formation of anatomical boundary striated muscle cell differentiation Bergmann glial cell differentiation |
Hedgehog signaling pathway Pathways in cancer Basal cell carcinoma |
221519_at |
0.333 |
7.992 |
2.655 |
1.786e-02 |
0.475 |
-3.047 |
FBXW4 |
F-box and WD repeat domain containing 4 |
10 |
-103360410 |
AF281859 |
6468 |
10q24 |
Hs.500822 |
16 |
ubiquitin ligase complex molecular_function ubiquitin-dependent protein catabolic process multicellular organismal development Wnt receptor signaling pathway embryonic limb morphogenesis limb development |
|
210381_s_at |
CCKBR |
cholecystokinin B receptor |
11 |
6237541 |
BC000740 |
887 |
11p15.4 |
Hs.203 |
74 |
phosphoinositide phospholipase C activity receptor activity G-protein coupled receptor activity protein binding membrane fraction plasma membrane integral to plasma membrane activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration digestion sensory perception feeding behavior positive regulation of cell proliferation gastrin receptor activity 1-phosphatidylinositol-3-kinase regulator activity |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
241817_at |
C3orf62 |
chromosome 3 open reading frame 62 |
3 |
-49281033 |
AA729235 |
375341 |
3p21.31 |
Hs.403828 |
3 |
|
|
222291_at |
0.855 |
4.141 |
5.180 |
1.071e-04 |
0.162 |
1.255 |
FAM149A |
family with sequence similarity 149, member A |
4 |
187302988, 187307320 |
AI478795 |
25854 |
4q35.1 |
Hs.357025 |
3 |
|
|
240607_at |
-0.323 |
6.006 |
-2.935 |
1.011e-02 |
0.415 |
-2.566 |
MIAT |
myocardial infarction associated transcript (non-protein coding) |
22 |
25383483 |
AI692560 |
440823 |
22q12.1 |
Hs.517502 |
3 |
|
|
217718_s_at |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide |
20 |
42947757 |
NM_014052 |
7529 |
20q13.1 |
Hs.643544 |
109 |
cytoplasm cytosol protein targeting Ras protein signal transduction activation of pro-apoptotic gene products enzyme binding protein domain specific binding negative regulation of protein amino acid dephosphorylation melanosome positive regulation of catalytic activity perinuclear region of cytoplasm |
Cell cycle Neurotrophin signaling pathway |
234195_at |
-0.248 |
5.146 |
-2.861 |
1.176e-02 |
0.426 |
-2.694 |
TNFRSF10C |
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
8 |
23016378 |
AK026079 |
8794 |
8p22-p21 |
Hs.655801 |
43 |
transmembrane receptor activity plasma membrane integral to plasma membrane apoptosis signal transduction anchored to membrane |
Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity |
226279_at |
PRSS23 |
protease, serine, 23 |
11 |
86189138 |
AW471145 |
11098 |
11q14.1 |
Hs.25338 |
13 |
serine-type endopeptidase activity extracellular region nucleus proteolysis peptidase activity |
|
208471_at |
0.410 |
4.720 |
2.851 |
1.202e-02 |
0.426 |
-2.712 |
HPR |
haptoglobin-related protein |
16 |
70654625 |
NM_020995 |
3250 |
16q22.1 |
Hs.655361 |
17 |
catalytic activity serine-type endopeptidase activity extracellular region proteolysis hemoglobin binding spherical high-density lipoprotein particle |
|
211746_x_at |
0.232 |
10.723 |
3.007 |
8.738e-03 |
0.394 |
-2.442 |
PSMA1 |
proteasome (prosome, macropain) subunit, alpha type, 1 |
11 |
-14492087, -14482998, -14482998 |
BC005932 |
5682 |
11p15.1 |
Hs.102798 Hs.445711 |
52 |
RNA binding threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex polysome ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
212296_at |
0.317 |
10.020 |
2.570 |
2.116e-02 |
0.497 |
-3.189 |
PSMD14 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 |
2 |
161873031 |
NM_005805 |
10213 |
2q24.2 |
Hs.567410 |
15 |
proteasome complex ubiquitin thiolesterase activity protein binding cytosol ubiquitin-dependent protein catabolic process peptidase activity metallopeptidase activity zinc ion binding anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process metal ion binding negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle protein K63-linked deubiquitination |
Proteasome |
210253_at |
0.354 |
4.230 |
2.582 |
2.066e-02 |
0.497 |
-3.169 |
HTATIP2 |
HIV-1 Tat interactive protein 2, 30kDa |
11 |
20341806, 20341822, 20341864, 20341978, 20342262 |
AF092095 |
10553 |
11p15.1 |
Hs.90753 |
31 |
RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction |
|
1556228_a_at |
0.289 |
5.248 |
2.314 |
3.502e-02 |
0.555 |
-3.610 |
VCPIP1 |
valosin containing protein (p97)/p47 complex interacting protein 1 |
8 |
-67705041 |
AF088033 |
80124 |
8q13 |
Hs.632066 |
16 |
ubiquitin-specific protease activity cytoplasm endoplasmic reticulum Golgi apparatus Golgi stack peptidase activity cysteine-type peptidase activity protein ubiquitination modification-dependent protein catabolic process |
|
228244_at |
BLOC1S3 |
biogenesis of lysosomal organelles complex-1, subunit 3 |
19 |
50373842 |
BF062383 |
388552 |
19q13.32 |
Hs.103902 Hs.719016 |
7 |
eye development molecular_function cytoplasm cytosol platelet activation BLOC-1 complex BLOC-1 complex melanosome organization positive regulation of natural killer cell activation secretion of lysosomal enzymes response to drug identical protein binding pigmentation during development platelet dense granule organization |
|
224513_s_at |
UBQLN4 |
ubiquilin 4 |
1 |
-154271715 |
BC006410 |
56893 |
1q21 |
Hs.283739 |
9 |
nucleus cytoplasm endoplasmic reticulum endoplasmic reticulum membrane cytosol biological_process identical protein binding |
|
220254_at |
LRP12 |
low density lipoprotein-related protein 12 |
8 |
-105570642 |
NM_013437 |
29967 |
8q22.2-q23.1 |
Hs.600630 |
8 |
receptor activity low-density lipoprotein receptor activity protein binding nucleolus cytoplasm plasma membrane integral to plasma membrane coated pit endocytosis signal transduction regulation of growth |
|
234329_at |
-0.252 |
3.485 |
-2.312 |
3.516e-02 |
0.555 |
-3.614 |
CLIC5 |
chloride intracellular channel 5 |
6 |
-45974165, -45974165 |
AL050336 |
53405 |
6p21.1-p12.1 |
Hs.485489 |
15 |
voltage-gated ion channel activity voltage-gated chloride channel activity protein binding insoluble fraction cytoplasm Golgi apparatus centrosome cell cortex ion transport chloride transport female pregnancy actin cytoskeleton membrane integral to membrane chloride ion binding chloride channel complex |
|
220901_at |
-0.574 |
5.578 |
-2.767 |
1.423e-02 |
0.446 |
-2.855 |
GPR157 |
G protein-coupled receptor 157 |
1 |
-9087062 |
NM_024980 |
80045 |
1p36.23 |
Hs.632367 |
5 |
G-protein coupled receptor activity plasma membrane G-protein coupled receptor protein signaling pathway integral to membrane |
|
235635_at |
ARHGAP5 |
Rho GTPase activating protein 5 |
14 |
31616245 |
N50119 |
394 |
14q12 |
Hs.592313 |
19 |
GTPase activity GTPase activator activity Rho GTPase activator activity GTP binding intracellular cytoplasm cell adhesion signal transduction small GTPase mediated signal transduction Rho protein signal transduction membrane SH2 domain binding |
Focal adhesion Leukocyte transendothelial migration |
1556121_at |
NAP1L1 |
nucleosome assembly protein 1-like 1 |
12 |
-74724938 |
AK021751 |
4673 |
12q21.2 |
Hs.524599 Hs.695185 |
17 |
protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome |
|
226494_at |
KIAA1543 |
KIAA1543 |
19 |
7566787 |
AB040976 |
57662 |
19p13.2 |
Hs.17686 |
9 |
molecular_function protein binding cellular_component biological_process |
|
222033_s_at |
-0.262 |
7.332 |
-2.231 |
4.117e-02 |
0.571 |
-3.744 |
FLT1 |
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) |
13 |
-27871181, -27857687, -27840233, -27772482 |
AA058828 |
2321 |
13q12 |
Hs.654360 |
228 |
nucleotide binding patterning of blood vessels receptor activity vascular endothelial growth factor receptor activity ATP binding extracellular region extracellular space cytoplasm plasma membrane plasma membrane integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway multicellular organismal development female pregnancy positive regulation of cell proliferation cell migration transferase activity growth factor binding cell differentiation positive regulation of vascular endothelial growth factor receptor signaling pathway identical protein binding |
Cytokine-cytokine receptor interaction Endocytosis Focal adhesion |
1554864_a_at |
SDC3 |
syndecan 3 |
1 |
-31114899 |
AF248634 |
9672 |
1pter-p22.3 |
Hs.158287 |
35 |
cytoskeletal protein binding membrane integral to membrane |
ECM-receptor interaction Cell adhesion molecules (CAMs) |
204336_s_at |
RGS19 |
regulator of G-protein signaling 19 |
20 |
-62174978, -62174978 |
NM_005873 |
10287 |
20q13.33 |
Hs.422336 |
25 |
signal transducer activity protein binding membrane fraction Golgi apparatus heterotrimeric G-protein complex autophagy G-protein coupled receptor protein signaling pathway small GTPase mediated signal transduction negative regulation of signal transduction membrane |
|
207922_s_at |
0.232 |
7.479 |
2.166 |
4.659e-02 |
0.582 |
-3.846 |
MAEA |
macrophage erythroblast attacher |
4 |
1273671 |
NM_005882 |
10296 |
4p16.3 |
Hs.139896 |
5 |
actin binding membrane fraction nucleus cytoplasm spindle contractile ring cytoskeleton plasma membrane integral to plasma membrane cell cycle cell adhesion regulation of mitotic cell cycle nuclear matrix negative regulation of myeloid cell apoptosis erythrocyte maturation cell division |
|
226247_at |
PLEKHA1 |
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
10 |
124124209, 124141832 |
AI346026 |
59338 |
10q26.13 |
Hs.643512 |
16 |
phospholipid binding cellular_component nucleus cytoplasm plasma membrane biological_process |
|
207257_at |
-0.192 |
4.767 |
-2.194 |
4.414e-02 |
0.579 |
-3.801 |
EPO |
erythropoietin |
7 |
100156358 |
NM_000799 |
2056 |
7q22 |
Hs.2303 |
177 |
response to hypoxia erythropoietin receptor binding hormone activity protein binding extracellular region extracellular space regulation of transcription from RNA polymerase II promoter apoptosis signal transduction embryo implantation blood circulation positive regulation of cell proliferation erythrocyte differentiation positive regulation of tyrosine phosphorylation of Stat5 protein hemoglobin biosynthetic process positive regulation of gene-specific transcription erythrocyte maturation positive regulation of DNA replication positive regulation of Ras protein signal transduction |
Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage |
201174_s_at |
0.384 |
8.264 |
3.829 |
1.605e-03 |
0.259 |
-1.001 |
TERF2IP |
telomeric repeat binding factor 2, interacting protein |
16 |
74239184 |
NM_018975 |
54386 |
16q23.1 |
Hs.301419 |
25 |
nuclear chromosome nuclear telomere cap complex DNA binding protein binding nucleus nucleoplasm cytoplasm telomere maintenance via telomerase Mre11 complex protection from non-homologous end joining at telomere negative regulation of telomere maintenance telomeric DNA binding regulation of transcription protein localization to telomere |
|
201323_at |
EBNA1BP2 |
EBNA1 binding protein 2 |
1 |
-43402432, -43402432 |
NM_006824 |
10969 |
1p35-p33 |
Hs.346868 |
20 |
protein binding membrane fraction nucleus nucleolus ribosome biogenesis |
|
214328_s_at |
HSP90AA1 |
heat shock protein 90kDa alpha (cytosolic), class A member 1 |
14 |
-101616827, -101616827 |
R01140 |
3320 |
14q32.33 |
Hs.525600 Hs.700831 |
275 |
nucleotide binding ATP binding cytoplasm cytosol cytosol mitochondrial transport response to unfolded protein signal transduction nitric-oxide synthase regulator activity TPR domain binding TPR domain binding cellular chaperone-mediated protein complex assembly protein refolding melanosome protein homodimerization activity positive regulation of nitric oxide biosynthetic process unfolded protein binding mitochondrial outer membrane translocase complex assembly |
Antigen processing and presentation Pathways in cancer Prostate cancer |
222664_at |
0.586 |
5.271 |
4.705 |
2.720e-04 |
0.175 |
0.489 |
KCTD15 |
potassium channel tetramerisation domain containing 15 |
19 |
38979590 |
AI808448 |
79047 |
19q13.11 |
Hs.221873 Hs.606506 |
12 |
voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane |
|
242545_at |
0.460 |
5.907 |
3.380 |
4.050e-03 |
0.323 |
-1.787 |
TTLL11 |
tubulin tyrosine ligase-like family, member 11 |
9 |
-123791010, -123624025 |
AA007347 |
158135 |
9q33.2 |
Hs.640663 Hs.644262 |
5 |
tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process ligase activity |
|
204980_at |
CLOCK |
clock homolog (mouse) |
4 |
-55993416 |
NM_004898 |
9575 |
4q12 |
Hs.436975 |
72 |
transcription factor activity histone acetyltransferase activity signal transducer activity protein binding nucleus transcription factor complex nucleolus cytoplasm signal transduction circadian rhythm acyltransferase activity photoperiodism transferase activity positive regulation of transcription from RNA polymerase II promoter |
Circadian rhythm - mammal |
224812_at |
HIBADH |
3-hydroxyisobutyrate dehydrogenase |
7 |
-27531585 |
AL577446 |
11112 |
7p15.2 |
Hs.406758 |
9 |
phosphogluconate dehydrogenase (decarboxylating) activity binding mitochondrion pentose-phosphate shunt valine metabolic process 3-hydroxyisobutyrate dehydrogenase activity oxidoreductase activity NAD or NADH binding oxidation reduction |
Valine, leucine and isoleucine degradation Metabolic pathways |
229872_s_at |
1.759 |
6.025 |
4.111 |
9.013e-04 |
0.220 |
-0.513 |
LOC100132999 |
hypothetical protein LOC100132999 |
1 |
|
AA532655 |
100132999 |
1q21.2 |
Hs.670106 |
|
|
|
201123_s_at |
1.022 |
9.932 |
3.405 |
3.854e-03 |
0.319 |
-1.745 |
EIF5A |
eukaryotic translation initiation factor 5A |
17 |
7151041, 7151579, 7152011, 7152417 |
NM_001970 |
1984 |
17p13-p12 |
Hs.534314 |
52 |
RNA binding translation initiation factor activity translation elongation factor activity nucleus annulate lamellae nuclear pore cytoplasm endoplasmic reticulum cytosol mRNA export from nucleus translation translational frameshifting protein export from nucleus nucleocytoplasmic transport nucleocytoplasmic transport induction of apoptosis cell proliferation peptidyl-lysine modification to hypusine peptidyl-lysine modification to hypusine protein transport membrane U6 snRNA binding viral genome replication ribosome binding positive regulation of translational elongation positive regulation of translational termination positive regulation of translational initiation protein N-terminus binding intracellular protein transmembrane transport |
|
220027_s_at |
RASIP1 |
Ras interacting protein 1 |
19 |
-53915653 |
NM_017805 |
54922 |
19q13.33 |
Hs.233955 |
4 |
cytoplasm Golgi apparatus Golgi stack signal transduction perinuclear region of cytoplasm |
|
214789_x_at |
0.279 |
7.334 |
2.274 |
3.786e-02 |
0.564 |
-3.675 |
SFRS2B |
splicing factor, arginine/serine-rich 2B |
11 |
94439703 |
AA524274 |
10929 |
11q22 |
Hs.476680 Hs.713908 |
6 |
nucleotide binding RNA binding nucleus mRNA processing RNA splicing |
|
1560145_at |
MKLN1 |
muskelin 1, intracellular mediator containing kelch motifs |
7 |
130445394, 130663134 |
BQ942131 |
4289 |
7q32 |
Hs.44693 |
13 |
protein binding cytoplasm signal transduction |
|
244409_at |
-0.319 |
6.286 |
-2.247 |
3.987e-02 |
0.568 |
-3.717 |
CCDC154 |
coiled-coil domain containing 154 |
16 |
-1424390 |
AW612232 |
645811 |
16p13.3 |
Hs.355232 |
1 |
|
|
226508_at |
0.242 |
7.975 |
2.393 |
3.001e-02 |
0.539 |
-3.482 |
PHC3 |
polyhomeotic homolog 3 (Drosophila) |
3 |
-171288061 |
AI042019 |
80012 |
3q26.2 |
Hs.529592 Hs.694467 |
10 |
DNA binding nucleus multicellular organismal development zinc ion binding metal ion binding |
|
224977_at |
C6orf89 |
chromosome 6 open reading frame 89 |
6 |
36961617 |
AL119182 |
221477 |
6p21.2 |
Hs.433381 |
10 |
membrane integral to membrane |
|
222457_s_at |
0.488 |
6.726 |
2.270 |
3.814e-02 |
0.565 |
-3.681 |
LIMA1 |
LIM domain and actin binding 1 |
12 |
-48855829, -48855829 |
BC001247 |
51474 |
12q13 |
Hs.525419 |
23 |
stress fiber actin monomer binding cytoplasm focal adhesion zinc ion binding actin cytoskeleton cell junction negative regulation of actin filament depolymerization ruffle organization metal ion binding actin filament binding actin filament bundle formation |
|
200059_s_at |
0.382 |
10.457 |
2.658 |
1.773e-02 |
0.473 |
-3.040 |
RHOA |
ras homolog gene family, member A |
3 |
-49371582 |
BC001360 |
387 |
3p21.3 |
Hs.247077 Hs.709788 |
348 |
nucleotide binding magnesium ion binding cell morphogenesis GTPase activity protein binding GTP binding intracellular nucleus cytoplasm cytoskeleton plasma membrane regulation of transcription from RNA polymerase II promoter cell adhesion cell-matrix adhesion small GTPase mediated signal transduction Rho protein signal transduction skeletal muscle tissue development myosin binding actin cytoskeleton organization cell differentiation positive regulation of NF-kappaB import into nucleus positive regulation of I-kappaB kinase/NF-kappaB cascade negative regulation of neuron apoptosis interspecies interaction between organisms negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of stress fiber formation |
Chemokine signaling pathway Vascular smooth muscle contraction Wnt signaling pathway TGF-beta signaling pathway Axon guidance Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer |
1554114_s_at |
SSH2 |
slingshot homolog 2 (Drosophila) |
17 |
-24977090 |
AB072359 |
85464 |
17q11.2 |
Hs.654754 |
11 |
actin binding protein tyrosine phosphatase activity cytoplasm cytoskeleton protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity actin cytoskeleton organization |
Regulation of actin cytoskeleton |
212219_at |
0.482 |
8.217 |
4.445 |
4.572e-04 |
0.193 |
0.057 |
PSME4 |
proteasome (prosome, macropain) activator subunit 4 |
2 |
-53944707 |
D38521 |
23198 |
2p16.2 |
Hs.413801 |
30 |
binding nucleus cytosol multicellular organismal development spermatogenesis nuclear speck cell differentiation protein complex |
Proteasome |
206875_s_at |
SLK |
STE20-like kinase (yeast) |
10 |
105717459 |
NM_014720 |
9748 |
10q24.33 |
Hs.591922 |
16 |
nucleotide binding DNA binding nuclease activity protein serine/threonine kinase activity ATP binding cytoplasm plasma membrane nucleotide-excision repair protein amino acid phosphorylation apoptosis transferase activity |
|
207991_x_at |
-0.319 |
3.844 |
-2.975 |
9.324e-03 |
0.401 |
-2.497 |
ACRV1 |
acrosomal vesicle protein 1 |
11 |
-125047438 |
NM_020113 |
56 |
11q23-q24 |
Hs.169222 Hs.596575 |
12 |
acrosomal vesicle multicellular organismal development |
|
204342_at |
SLC25A24 |
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
1 |
-108478969, -108478969 |
NM_013386 |
29957 |
1p13.3 |
Hs.656870 |
4 |
binding calcium ion binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
225522_at |
0.586 |
7.015 |
2.731 |
1.533e-02 |
0.457 |
-2.918 |
AAK1 |
AP2 associated kinase 1 |
2 |
-69538630 |
AW628987 |
22848 |
2p14 |
Hs.468878 |
19 |
nucleotide binding protein serine/threonine kinase activity ATP binding plasma membrane coated pit protein amino acid phosphorylation transferase activity |
|
216854_at |
GDF11 |
growth differentiation factor 11 |
12 |
54423330 |
AF028333 |
10220 |
12q13.2 |
Hs.600883 |
10 |
skeletal system development ureteric bud development cytokine activity protein binding extracellular region extracellular space nervous system development mesoderm development growth factor activity negative regulation of cell proliferation organ morphogenesis spinal cord anterior/posterior patterning pancreas development growth negative regulation of cell differentiation cell maturation camera-type eye morphogenesis |
|
217771_at |
0.636 |
4.486 |
3.343 |
4.375e-03 |
0.328 |
-1.853 |
GOLM1 |
golgi membrane protein 1 |
9 |
-87830877, -87830877 |
NM_016548 |
51280 |
9q21.33 |
Hs.494337 |
22 |
Golgi apparatus integral to plasma membrane membrane |
|
243901_at |
ALDOB |
aldolase B, fructose-bisphosphate |
9 |
-103222662 |
AV658701 |
229 |
9q21.3-q22.2 |
Hs.530274 |
40 |
fructose-bisphosphate aldolase activity microtubule organizing center glycolysis NADH oxidation cytoskeletal protein binding metabolic process lyase activity fructose 1,6-bisphosphate metabolic process positive regulation of ATPase activity centriolar satellite identical protein binding ATPase binding fructose binding vacuolar proton-transporting V-type ATPase complex assembly |
Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
225125_at |
MMGT1 |
membrane magnesium transporter 1 |
X |
-134871896 |
BF978280 |
93380 |
Xq26.3 |
Hs.110702 |
7 |
magnesium ion binding cytoplasm early endosome endoplasmic reticulum Golgi apparatus plasma membrane transport cobalt ion transport copper ion transport cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity magnesium ion transmembrane transporter activity ferrous iron transport magnesium ion transport integral to membrane |
|
206995_x_at |
-0.543 |
4.988 |
-4.096 |
9.285e-04 |
0.222 |
-0.538 |
SCARF1 |
scavenger receptor class F, member 1 |
17 |
-1483902, -1483901 |
NM_003693 |
8578 |
17p13.3 |
Hs.647430 |
6 |
scavenger receptor activity protein binding cholesterol catabolic process receptor-mediated endocytosis cell adhesion membrane integral to membrane low-density lipoprotein binding |
|
227903_x_at |
0.316 |
4.755 |
3.515 |
3.068e-03 |
0.301 |
-1.551 |
C19orf20 |
chromosome 19 open reading frame 20 |
19 |
458496 |
AI990682 |
91978 |
19p13.3 |
Hs.369613 |
6 |
cytoplasm centrosome cytoskeleton microtubule cilium microtubule basal body multicellular organismal development spermatogenesis flagellum cell differentiation axon dendrite cilium axoneme flagellar axoneme |
|
238478_at |
0.460 |
5.713 |
2.468 |
2.590e-02 |
0.518 |
-3.359 |
BNC2 |
basonuclin 2 |
9 |
-16399500 |
H97386 |
54796 |
9p22.3-p22.2 |
Hs.656581 Hs.693437 |
10 |
intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding |
|
207877_s_at |
NVL |
nuclear VCP-like |
1 |
-222481658 |
NM_002533 |
4931 |
1q41-q42.2 |
Hs.497867 |
10 |
nucleotide binding ATP binding nucleus nucleolus nucleoside-triphosphatase activity |
|
203643_at |
ERF |
Ets2 repressor factor |
19 |
-47443556 |
NM_006494 |
2077 |
19q13 |
Hs.655969 |
17 |
transcription factor activity ligand-regulated transcription factor activity transcription corepressor activity nucleus regulation of transcription from RNA polymerase II promoter cell proliferation sequence-specific DNA binding |
|
223708_at |
C1QTNF4 |
C1q and tumor necrosis factor related protein 4 |
11 |
-47567791 |
AF329838 |
114900 |
11q11 |
Hs.662633 |
3 |
extracellular region |
|
209214_s_at |
EWSR1 |
Ewing sarcoma breakpoint region 1 |
22 |
27993997, 27993997 |
BC004817 |
2130 |
22q12.2 |
Hs.374477 |
90 |
nucleotide binding RNA binding calmodulin binding intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding |
|
218694_at |
ARMCX1 |
armadillo repeat containing, X-linked 1 |
X |
100692169 |
NM_016608 |
51309 |
Xq21.33-q22.2 |
Hs.9728 |
8 |
binding membrane integral to membrane |
|
209398_at |
HIST1H1C |
histone cluster 1, H1c |
6 |
-26163946 |
BC002649 |
3006 |
6p21.3 |
Hs.7644 |
17 |
nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly nucleosome positioning |
|
1553429_at |
FLJ31713 |
hypothetical protein FLJ31713 |
9 |
|
NM_152575 |
158263 |
9q32 |
Hs.350785 |
1 |
|
|
229068_at |
CCT5 |
chaperonin containing TCP1, subunit 5 (epsilon) |
5 |
10303281 |
BF197357 |
22948 |
5p15.2 |
Hs.1600 |
30 |
nucleotide binding ATP binding nucleus nucleolus cytoplasm chaperonin-containing T-complex protein folding unfolded protein binding |
|
46323_at |
-0.490 |
6.002 |
-4.124 |
8.764e-04 |
0.219 |
-0.489 |
CANT1 |
calcium activated nucleotidase 1 |
17 |
-74499392 |
AL120741 |
124583 |
17q25.3 |
Hs.8859 |
13 |
signal transducer activity calcium ion binding endoplasmic reticulum Golgi apparatus membrane integral to membrane hydrolase activity nucleoside-diphosphatase activity positive regulation of I-kappaB kinase/NF-kappaB cascade |
Purine metabolism Pyrimidine metabolism |
234870_at |
TANC1 |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
2 |
159533391 |
AK000401 |
85461 |
2q24.2 |
Hs.61590 |
6 |
binding plasma membrane postsynaptic density cell junction synapse postsynaptic membrane |
|
1556006_s_at |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
BQ025347 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
231480_at |
SLC6A19 |
solute carrier family 6 (neutral amino acid transporter), member 19 |
5 |
1254709 |
AI636105 |
340024 |
5p15.33 |
Hs.481478 |
10 |
neurotransmitter:sodium symporter activity integral to plasma membrane neurotransmitter transport neutral amino acid transmembrane transporter activity symporter activity neutral amino acid transport membrane |
|
208776_at |
0.485 |
7.169 |
2.853 |
1.195e-02 |
0.426 |
-2.707 |
PSMD11 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
17 |
27795614 |
BF432873 |
5717 |
17q11.2 |
Hs.655396 |
41 |
proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
231871_at |
0.463 |
4.686 |
3.720 |
2.011e-03 |
0.273 |
-1.192 |
GPR180 |
G protein-coupled receptor 180 |
13 |
94052104 |
AU160685 |
160897 |
13q32.1 |
Hs.657472 |
7 |
membrane integral to membrane |
|
219250_s_at |
FLRT3 |
fibronectin leucine rich transmembrane protein 3 |
20 |
-14252642, -14252642 |
NM_013281 |
23767 |
20p11 |
Hs.41296 |
9 |
receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging |
|
213464_at |
SHC2 |
SHC (Src homology 2 domain containing) transforming protein 2 |
19 |
-367582 |
AV705938 |
25759 |
19p13.3 |
Hs.30965 |
11 |
protein binding cellular_component intracellular signaling cascade Ras protein signal transduction |
ErbB signaling pathway Chemokine signaling pathway VEGF signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity Neurotrophin signaling pathway Insulin signaling pathway Glioma Chronic myeloid leukemia |
212036_s_at |
0.603 |
7.762 |
4.061 |
9.976e-04 |
0.224 |
-0.598 |
PNN |
pinin, desmosome associated protein |
14 |
38714137 |
AW152664 |
5411 |
14q21.1 |
Hs.409965 |
30 |
DNA binding structural molecule activity protein binding nucleus spliceosomal complex nucleolus cytoplasm intermediate filament plasma membrane mRNA processing cell adhesion RNA splicing nuclear speck desmosome regulation of transcription |
|
210564_x_at |
0.684 |
7.111 |
3.192 |
5.976e-03 |
0.357 |
-2.118 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AF009619 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
204326_x_at |
1.274 |
10.673 |
4.616 |
3.245e-04 |
0.179 |
0.343 |
MT1X |
metallothionein 1X |
16 |
55273882 |
NM_002450 |
4501 |
16q13 |
Hs.374950 |
18 |
copper ion binding zinc ion binding response to metal ion cadmium ion binding metal ion binding |
|
226080_at |
SSH2 |
slingshot homolog 2 (Drosophila) |
17 |
-24977090 |
BE676214 |
85464 |
17q11.2 |
Hs.654754 |
11 |
actin binding protein tyrosine phosphatase activity cytoplasm cytoskeleton protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity actin cytoskeleton organization |
Regulation of actin cytoskeleton |
216512_s_at |
DCT |
dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) |
13 |
-93889841 |
AL139318 |
1638 |
13q32 |
Hs.301865 |
41 |
dopachrome isomerase activity copper ion binding microsome cytosol melanin biosynthetic process from tyrosine metabolic process zinc ion binding epidermis development membrane integral to membrane oxidoreductase activity isomerase activity melanosome metal ion binding pigmentation during development cell development |
Tyrosine metabolism Metabolic pathways Melanogenesis |
201938_at |
0.317 |
10.263 |
2.777 |
1.395e-02 |
0.442 |
-2.838 |
CDK2AP1 |
cyclin-dependent kinase 2 associated protein 1 |
12 |
-122311492 |
NM_004642 |
8099 |
12q24.31 |
Hs.719107 |
15 |
S phase of mitotic cell cycle DNA binding protein binding nucleus cytoplasm DNA-dependent DNA replication protein amino acid phosphorylation cell cycle |
|
227343_at |
MYEOV |
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas) |
11 |
68818197 |
AK026148 |
26579 |
11q13 |
Hs.523848 |
8 |
|
|
231240_at |
0.572 |
3.524 |
3.528 |
2.989e-03 |
0.300 |
-1.529 |
DIO2 |
deiodinase, iodothyronine, type II |
14 |
-79733621, -79733621 |
AI038059 |
1734 |
14q24.2-q24.3 |
Hs.202354 |
61 |
selenocysteine incorporation thyroxine 5'-deiodinase activity thyroid hormone generation selenium binding membrane integral to membrane thyroid hormone catabolic process hormone biosynthetic process oxidation reduction |
|
208266_at |
C8orf17 |
chromosome 8 open reading frame 17 |
8 |
|
NM_020237 |
56988 |
8q24.3 |
Hs.283098 |
2 |
cytoplasm endoplasmic reticulum endoplasmic reticulum membrane microsome membrane |
|
240230_s_at |
LOC642826 |
hypothetical LOC642826 |
10 |
-46662697, 47805861 |
AW000942 |
642826 |
10q11.22 |
Hs.463017 Hs.647204 Hs.711074 Hs.711898 Hs.718802 |
2 |
|
|
223790_at |
KATNAL1 |
katanin p60 subunit A-like 1 |
13 |
-29674766, -29674766 |
BC000612 |
84056 |
13q12.3 |
Hs.243596 |
7 |
nucleotide binding ATP binding microtubule microtubule-severing ATPase activity hydrolase activity nucleoside-triphosphatase activity |
|
1554217_a_at |
0.466 |
2.834 |
2.925 |
1.034e-02 |
0.418 |
-2.584 |
CCDC132 |
coiled-coil domain containing 132 |
7 |
92699588, 92699588 |
BC017888 |
55610 |
7q21.3 |
Hs.222282 |
5 |
|
|
235602_at |
TP53INP1 |
tumor protein p53 inducible nuclear protein 1 |
8 |
-96007376 |
AI422387 |
94241 |
8q22 |
Hs.492261 |
16 |
nucleus apoptosis |
|
225398_at |
RPUSD4 |
RNA pseudouridylate synthase domain containing 4 |
11 |
-125577199 |
AL580514 |
84881 |
11q24.2 |
Hs.150458 |
5 |
pseudouridine synthesis RNA binding pseudouridine synthase activity |
|
220937_s_at |
0.509 |
6.770 |
3.064 |
7.775e-03 |
0.381 |
-2.342 |
ST6GALNAC4 |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
9 |
-129709985 |
NM_014403 |
27090 |
9q34 |
Hs.3972 Hs.709827 |
13 |
soluble fraction nucleus Golgi apparatus protein amino acid glycosylation glycolipid metabolic process membrane integral to membrane integral to Golgi membrane (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity |
Glycosphingolipid biosynthesis - ganglio series Metabolic pathways |
203403_s_at |
RNF6 |
ring finger protein (C3H2C3 type) 6 |
13 |
-25684904, -25684904, -25684904 |
NM_005977 |
6049 |
13q12.2 |
Hs.136885 |
7 |
protein binding cellular_component biological_process zinc ion binding metal ion binding |
|
215979_s_at |
SLC7A1 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
13 |
-28981551 |
AK022999 |
6541 |
13q12-q14 |
Hs.14846 |
23 |
receptor activity integral to plasma membrane transport amino acid transport amino acid transmembrane transporter activity arginine transmembrane transporter activity arginine transport membrane |
|
221532_s_at |
WDR61 |
WD repeat domain 61 |
15 |
-76362632 |
AF309553 |
80349 |
15q25.1 |
Hs.513055 |
6 |
|
RNA degradation |
205738_s_at |
FABP3 |
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
1 |
-31610686 |
NM_004102 |
2170 |
1p33-p32 |
Hs.657242 |
35 |
transporter activity cytoplasm phosphatidylcholine biosynthetic process transport negative regulation of cell proliferation lipid binding |
PPAR signaling pathway |
244881_at |
0.328 |
5.916 |
2.744 |
1.493e-02 |
0.453 |
-2.895 |
LMLN |
leishmanolysin-like (metallopeptidase M8 family) |
3 |
199171467 |
AA629059 |
89782 |
3q29 |
Hs.518540 |
2 |
metalloendopeptidase activity cytoplasm proteolysis cell cycle mitosis cell adhesion peptidase activity zinc ion binding membrane metal ion binding cell division |
|
213503_x_at |
1.052 |
9.477 |
4.119 |
8.858e-04 |
0.219 |
-0.498 |
ANXA2 |
annexin A2 |
15 |
-58426642, -58426641 |
BE908217 |
302 |
15q21-q22 |
Hs.511605 |
137 |
skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm |
|
226736_at |
1.721 |
7.588 |
2.839 |
1.232e-02 |
0.427 |
-2.733 |
CHURC1 |
churchill domain containing 1 |
14 |
64450892 |
BE568660 |
91612 |
14q23.3 |
Hs.325531 |
5 |
multicellular organismal development zinc ion binding transcription activator activity positive regulation of transcription metal ion binding |
|
230904_at |
FSD1L |
fibronectin type III and SPRY domain containing 1-like |
9 |
107250135, 107250135, 107250145 |
W42665 |
83856 |
9q31 |
Hs.136901 |
4 |
molecular_function cellular_component biological_process |
|
200866_s_at |
0.543 |
8.333 |
2.845 |
1.215e-02 |
0.426 |
-2.721 |
PSAP |
prosaposin |
10 |
-73246060 |
M32221 |
5660 |
10q21-q22 |
Hs.523004 Hs.705948 |
76 |
extracellular space lysosome Golgi apparatus lipid metabolic process glycosphingolipid metabolic process lipid transport enzyme activator activity lipid binding integral to membrane |
Lysosome |
212232_at |
FNBP4 |
formin binding protein 4 |
11 |
-47694644 |
AB023231 |
23360 |
11p11.2 |
Hs.6834 |
11 |
protein binding |
|
229702_at |
CSNK1G3 |
casein kinase 1, gamma 3 |
5 |
122875691 |
BF516404 |
1456 |
5q23 |
Hs.129206 |
6 |
nucleotide binding protein serine/threonine kinase activity ATP binding cytoplasm protein modification process protein amino acid phosphorylation signal transduction Wnt receptor signaling pathway transferase activity |
Hedgehog signaling pathway |
209206_at |
SEC22B |
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) |
1 |
143807763 |
AV701283 |
9554 |
1q21.1 |
Hs.632438 Hs.715002 |
13 |
protein binding endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus ER to Golgi vesicle-mediated transport protein transport membrane integral to membrane vesicle-mediated transport melanosome |
SNARE interactions in vesicular transport |
201375_s_at |
0.390 |
10.090 |
3.217 |
5.674e-03 |
0.356 |
-2.074 |
PPP2CB |
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform |
8 |
-30762667 |
NM_004156 |
5516 |
8p12 |
Hs.491440 |
40 |
protein phosphatase type 2A complex chromosome, centromeric region protein serine/threonine phosphatase activity iron ion binding protein binding nucleus cytoplasm spindle protein amino acid dephosphorylation regulation of gene expression hydrolase activity manganese ion binding response to hydrogen peroxide negative regulation of apoptosis proteasomal ubiquitin-dependent protein catabolic process response to antibiotic metal ion binding |
Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression |
221550_at |
COX15 |
COX15 homolog, cytochrome c oxidase assembly protein (yeast) |
10 |
-101458494 |
BC002382 |
1355 |
10q24 |
Hs.28326 |
9 |
catalytic activity cytochrome-c oxidase activity mitochondrial respiratory chain mitochondrial electron transport, cytochrome c to oxygen protein complex assembly heme a biosynthetic process respiratory gaseous exchange respiratory chain complex IV assembly membrane integral to membrane mitochondrial part cellular respiration oxidation reduction |
Oxidative phosphorylation Porphyrin and chlorophyll metabolism Metabolic pathways |
207980_s_at |
CITED2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
6 |
-139735089 |
NM_006079 |
10370 |
6q23.3 |
Hs.82071 |
21 |
negative regulation of transcription from RNA polymerase II promoter nuclear chromatin response to hypoxia liver development transcription factor activity transcription coactivator activity transcription corepressor activity protein binding nucleus anti-apoptosis determination of left/right symmetry heart development heart development positive regulation of specific transcription from RNA polymerase II promoter positive regulation of cell-cell adhesion negative regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway response to fluid shear stress positive regulation of cell cycle positive regulation of transcription, DNA-dependent |
|
203475_at |
-0.246 |
4.197 |
-2.937 |
1.009e-02 |
0.415 |
-2.563 |
CYP19A1 |
cytochrome P450, family 19, subfamily A, polypeptide 1 |
15 |
-49287545 |
NM_000103 |
1588 |
15q21.1 |
Hs.260074 |
375 |
membrane fraction endoplasmic reticulum steroid biosynthetic process steroid biosynthetic process electron carrier activity membrane oxygen binding heme binding metal ion binding oxidation reduction aromatase activity |
Androgen and estrogen metabolism Metabolic pathways |
224630_at |
0.324 |
7.942 |
3.121 |
6.918e-03 |
0.370 |
-2.243 |
ERLEC1 |
endoplasmic reticulum lectin 1 |
2 |
53867571 |
AK001913 |
27248 |
2p16.2 |
Hs.438336 Hs.713845 |
10 |
protein binding endoplasmic reticulum endoplasmic reticulum lumen |
|
211317_s_at |
0.703 |
7.298 |
3.195 |
5.943e-03 |
0.357 |
-2.114 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AF041461 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
232941_at |
TMPRSS6 |
transmembrane protease, serine 6 |
22 |
-35791424 |
AA609066 |
164656 |
22q12.3 |
Hs.370885 |
16 |
angiogenesis serine-type endopeptidase activity plasma membrane proteolysis intracellular signaling cascade peptidase activity integral to membrane extracellular matrix organization fibrinolysis |
|
207643_s_at |
0.268 |
6.990 |
2.191 |
4.440e-02 |
0.580 |
-3.806 |
TNFRSF1A |
tumor necrosis factor receptor superfamily, member 1A |
12 |
-6308183 |
NM_001065 |
7132 |
12p13.2 |
Hs.279594 Hs.713833 |
271 |
receptor activity tumor necrosis factor receptor activity protein binding extracellular region plasma membrane plasma membrane integral to plasma membrane prostaglandin metabolic process apoptosis signal transduction cytokine-mediated signaling pathway positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms membrane raft positive regulation of transcription from RNA polymerase II promoter positive regulation of inflammatory response |
MAPK signaling pathway Cytokine-cytokine receptor interaction Apoptosis Adipocytokine signaling pathway Alzheimer's disease Amyotrophic lateral sclerosis (ALS) |
222848_at |
0.298 |
2.939 |
2.931 |
1.021e-02 |
0.417 |
-2.574 |
CENPK |
centromere protein K |
5 |
-64849348 |
BC005400 |
64105 |
5p15.2-q12.3 |
Hs.529778 |
9 |
chromosome, centromeric region protein binding nucleus chromosome positive regulation of transcription from RNA polymerase II promoter |
|
1558533_at |
KRBA2 |
KRAB-A domain containing 2 |
17 |
-8212697 |
BC024723 |
124751 |
17p13.1 |
Hs.304604 |
1 |
DNA binding intracellular regulation of transcription, DNA-dependent DNA integration |
|
205331_s_at |
REEP2 |
receptor accessory protein 2 |
5 |
137802674 |
NM_016606 |
51308 |
5q31 |
Hs.416090 |
10 |
membrane integral to membrane |
|
218782_s_at |
0.338 |
3.153 |
2.650 |
1.801e-02 |
0.476 |
-3.054 |
ATAD2 |
ATPase family, AAA domain containing 2 |
8 |
-124401271 |
NM_014109 |
29028 |
8q24.13 |
Hs.370834 |
9 |
nucleotide binding transcription factor activity ATP binding nucleus hydrolase activity nucleoside-triphosphatase activity ATPase activity, uncoupled regulation of transcription |
|
216840_s_at |
0.718 |
6.806 |
4.002 |
1.126e-03 |
0.229 |
-0.701 |
LAMA2 |
laminin, alpha 2 |
6 |
129245978 |
AK026829 |
3908 |
6q22-q23 |
Hs.200841 |
40 |
receptor binding structural molecule activity extracellular region basal lamina laminin-1 complex muscle organ development regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission, cholinergic sarcolemma regulation of embryonic development |
Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
201235_s_at |
BTG2 |
BTG family, member 2 |
1 |
201541286 |
BG339064 |
7832 |
1q32 |
Hs.519162 |
45 |
protein binding DNA repair protein amino acid methylation response to DNA damage stimulus negative regulation of cell proliferation anterior/posterior pattern formation neuron differentiation negative regulation of apoptosis regulation of transcription |
|
226770_at |
MAGI3 |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
1 |
113734997, 113734997 |
AI692181 |
260425 |
1p12-p11.2 |
Hs.486189 |
13 |
nucleotide binding protein binding ATP binding nucleus plasma membrane tight junction cell junction interspecies interaction between organisms |
Tight junction |
238177_at |
SLC6A19 |
solute carrier family 6 (neutral amino acid transporter), member 19 |
5 |
1254709 |
AA873542 |
340024 |
5p15.33 |
Hs.481478 |
10 |
neurotransmitter:sodium symporter activity integral to plasma membrane neurotransmitter transport neutral amino acid transmembrane transporter activity symporter activity neutral amino acid transport membrane |
|
219167_at |
-0.412 |
6.961 |
-2.571 |
2.112e-02 |
0.497 |
-3.188 |
RASL12 |
RAS-like, family 12 |
15 |
-63132727 |
NM_016563 |
51285 |
15q11.2-q22.33 |
Hs.27018 |
3 |
nucleotide binding GTP binding small GTPase mediated signal transduction |
|
208503_s_at |
GATAD1 |
GATA zinc finger domain containing 1 |
7 |
91914700 |
NM_021167 |
57798 |
7q21-q22 |
Hs.21145 |
6 |
transcription factor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding |
|
238560_at |
-0.380 |
6.005 |
-4.104 |
9.127e-04 |
0.220 |
-0.523 |
CALCOCO2 |
calcium binding and coiled-coil domain 2 |
17 |
44263370 |
AI684710 |
10241 |
17q21.32 |
Hs.514920 |
11 |
protein binding soluble fraction nucleus cytoplasm Golgi apparatus cytoskeleton viral reproduction response to interferon-gamma protein homodimerization activity perinuclear region of cytoplasm |
|
222924_at |
SLMAP |
sarcolemma associated protein |
3 |
57718213 |
BF526855 |
7871 |
3p21.2-p14.3 |
Hs.476432 |
11 |
smooth endoplasmic reticulum plasma membrane integral to plasma membrane protein folding muscle contraction prefoldin complex unfolded protein binding |
|
209368_at |
0.755 |
5.544 |
3.428 |
3.672e-03 |
0.314 |
-1.704 |
EPHX2 |
epoxide hydrolase 2, cytoplasmic |
8 |
27404561 |
AF233336 |
2053 |
8p21-p12 |
Hs.212088 |
54 |
magnesium ion binding prostaglandin production during acute inflammatory response 4-nitrophenylphosphatase activity epoxide hydrolase activity soluble fraction cytoplasm peroxisome cytosol oxygen and reactive oxygen species metabolic process xenobiotic metabolic process cellular calcium ion homeostasis inflammatory response metabolic process response to toxin hydrolase activity drug metabolic process sensory perception of pain aromatic compound catabolic process protein homodimerization activity linoleic acid metabolic process positive regulation of blood pressure positive regulation of vasodilation |
Arachidonic acid metabolism Tetrachloroethene degradation Metabolic pathways |
1561041_at |
TNRC6C |
trinucleotide repeat containing 6C |
17 |
73511912 |
BM459591 |
57690 |
17q25.3 |
Hs.569831 Hs.584945 |
10 |
nucleotide binding RNA binding regulation of translation gene silencing by RNA |
|
221747_at |
0.429 |
7.501 |
3.380 |
4.052e-03 |
0.323 |
-1.788 |
TNS1 |
tensin 1 |
2 |
-218372756 |
AL046979 |
7145 |
2q35-q36 |
Hs.471381 |
16 |
actin binding protein binding cytoplasm cytoskeleton focal adhesion cell junction |
|
210672_s_at |
0.324 |
6.099 |
2.894 |
1.100e-02 |
0.424 |
-2.637 |
C16orf35 |
chromosome 16 open reading frame 35 |
16 |
-75803, -75803 |
BC004185 |
8131 |
16p13.3 |
Hs.19699 |
6 |
molecular_function cellular_component biological_process |
|
217077_s_at |
GABBR2 |
gamma-aminobutyric acid (GABA) B receptor, 2 |
9 |
-100090186 |
AF095723 |
9568 |
9q22.1-q22.3 |
Hs.198612 |
27 |
receptor activity G-protein coupled receptor activity GABA-B receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane signal transduction negative regulation of adenylate cyclase activity gamma-aminobutyric acid signaling pathway synaptic transmission cell junction neuron projection synapse postsynaptic membrane |
Neuroactive ligand-receptor interaction |
229689_s_at |
DLG5 |
discs, large homolog 5 (Drosophila) |
10 |
-79220554 |
AV721789 |
9231 |
10q23 |
Hs.652690 |
49 |
protein binding intracellular cytoplasm plasma membrane cell-cell adherens junction intracellular signaling cascade negative regulation of cell proliferation cell-cell adhesion cell junction receptor signaling complex scaffold activity regulation of apoptosis |
|
228433_at |
0.319 |
5.286 |
3.022 |
8.477e-03 |
0.388 |
-2.416 |
NFYA |
nuclear transcription factor Y, alpha |
6 |
41148684 |
AU157605 |
4800 |
6p21.3 |
Hs.10441 |
55 |
transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter CCAAT-binding factor complex |
Antigen processing and presentation |
211060_x_at |
0.310 |
8.053 |
2.717 |
1.574e-02 |
0.459 |
-2.940 |
GPAA1 |
glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) |
8 |
145209511 |
BC006383 |
8733 |
8q24.3 |
Hs.627962 |
16 |
GPI-anchor transamidase activity protein binding endoplasmic reticulum protein complex assembly protein retention in ER lumen tubulin binding membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein attachment of GPI anchor to protein GPI anchor binding GPI-anchor transamidase complex |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways |
236814_at |
MDM4 |
Mdm4 p53 binding protein homolog (mouse) |
1 |
202752133 |
AA745971 |
4194 |
1q32 |
Hs.497492 |
68 |
negative regulation of transcription from RNA polymerase II promoter protein binding intracellular nucleus protein complex assembly apoptosis zinc ion binding negative regulation of cell proliferation negative regulation of protein catabolic process G0 to G1 transition metal ion binding protein stabilization |
p53 signaling pathway |
203430_at |
0.249 |
10.424 |
2.133 |
4.964e-02 |
0.591 |
-3.898 |
HEBP2 |
heme binding protein 2 |
6 |
138767028 |
NM_014320 |
23593 |
6q24 |
Hs.486589 |
8 |
cytoplasm |
|
231899_at |
ZC3H12C |
zinc finger CCCH-type containing 12C |
11 |
109469296 |
AB051513 |
85463 |
11q22.3 |
Hs.376289 |
3 |
magnesium ion binding endonuclease activity zinc ion binding hydrolase activity |
|
1558924_s_at |
1.382 |
6.486 |
4.185 |
7.743e-04 |
0.211 |
-0.385 |
CLIP1 |
CAP-GLY domain containing linker protein 1 |
12 |
-121321933 |
BF673049 |
6249 |
12q24.3 |
Hs.524809 |
37 |
kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding |
|
1554553_s_at |
YIF1B |
Yip1 interacting factor homolog B (S. cerevisiae) |
19 |
-43486039, -43486039, -43486039 |
BC014974 |
90522 |
19q13.2 |
Hs.280741 Hs.631544 |
4 |
membrane integral to membrane |
|
201027_s_at |
0.296 |
7.408 |
2.198 |
4.383e-02 |
0.578 |
-3.796 |
EIF5B |
eukaryotic translation initiation factor 5B |
2 |
99320265 |
NM_015904 |
9669 |
2q11.2 |
Hs.158688 |
15 |
nucleotide binding translation initiation factor activity translation initiation factor activity GTPase activity protein binding GTP binding cytoplasm translation regulation of translational initiation regulation of translational initiation |
|
232913_at |
TMED8 |
transmembrane emp24 protein transport domain containing 8 |
14 |
-76877866 |
AC007954 |
283578 |
14q24.3 |
Hs.200413 Hs.26403 |
6 |
|
|
227357_at |
MAP3K7IP3 |
mitogen-activated protein kinase kinase kinase 7 interacting protein 3 |
X |
-30755479 |
BF593914 |
257397 |
Xp21.2 |
Hs.188256 |
10 |
protein binding intracellular zinc ion binding metal ion binding |
|
225534_at |
C8orf40 |
chromosome 8 open reading frame 40 |
8 |
42515454, 42515874, 42515921, 42516095 |
AV711345 |
114926 |
8p11.21 |
Hs.655320 |
4 |
membrane integral to membrane |
|
231647_s_at |
FCRL5 |
Fc receptor-like 5 |
1 |
-155749790 |
AW241983 |
83416 |
1q21 |
Hs.415950 |
15 |
receptor activity plasma membrane integral to membrane |
|
202023_at |
EFNA1 |
ephrin-A1 |
1 |
153366972 |
NM_004428 |
1942 |
1q21-q22 |
Hs.516664 |
44 |
plasma membrane integral to plasma membrane cell-cell signaling anchored to membrane ephrin receptor binding |
Axon guidance |
225537_at |
TRAPPC6B |
trafficking protein particle complex 6B |
14 |
-38686765 |
AA936745 |
122553 |
14q21.1 |
Hs.13303 |
5 |
endoplasmic reticulum Golgi apparatus vesicle-mediated transport |
|
213489_at |
0.504 |
7.624 |
2.372 |
3.128e-02 |
0.543 |
-3.516 |
MAPRE2 |
microtubule-associated protein, RP/EB family, member 2 |
18 |
30810889, 30812205, 30875321 |
BE671156 |
10982 |
18q12.1-q12.2 |
Hs.532824 |
27 |
cytoplasm microtubule cell cycle mitosis signal transduction microtubule binding cell proliferation cell division |
|
226261_at |
0.389 |
3.504 |
3.076 |
7.588e-03 |
0.378 |
-2.322 |
ZNRF2 |
zinc and ring finger 2 |
7 |
30290447 |
AI831561 |
223082 |
7p14.3 |
Hs.487869 |
4 |
protein binding lysosome endosome plasma membrane zinc ion binding ligase activity modification-dependent protein catabolic process cell junction synapse metal ion binding |
|
200722_s_at |
CAPRIN1 |
cell cycle associated protein 1 |
11 |
34029805, 34029805 |
BG258784 |
4076 |
11p13 |
Hs.471818 |
10 |
protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection |
|
204378_at |
BCAS1 |
breast carcinoma amplified sequence 1 |
20 |
-51993485 |
NM_003657 |
8537 |
20q13.2 |
Hs.400556 |
12 |
protein binding cytoplasm |
|
203384_s_at |
GOLGA1 |
golgi autoantigen, golgin subfamily a, 1 |
9 |
-126680394 |
NM_002077 |
2800 |
9q33.3 |
Hs.133469 Hs.59504 |
11 |
Golgi apparatus membrane |
|
227933_at |
LINGO1 |
leucine rich repeat and Ig domain containing 1 |
15 |
-75692423 |
AI193252 |
84894 |
15q24.3 |
Hs.656765 |
14 |
|
|
233470_at |
PTPN5 |
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) |
11 |
-18706050 |
U27831 |
84867 |
11p15.1 |
Hs.79092 |
10 |
protein tyrosine phosphatase activity protein amino acid dephosphorylation integral to membrane hydrolase activity |
MAPK signaling pathway |
244783_at |
YAF2 |
YY1 associated factor 2 |
12 |
-40837173 |
R56794 |
10138 |
12q12 |
Hs.708084 |
9 |
transcription coactivator activity transcription corepressor activity protein binding intracellular nucleus zinc ion binding negative regulation of transcription positive regulation of transcription metal ion binding |
|
212878_s_at |
0.496 |
7.919 |
3.094 |
7.313e-03 |
0.376 |
-2.290 |
KLC1 |
kinesin light chain 1 |
14 |
103165277, 103165277 |
AA284075 |
3831 |
14q32.3 |
Hs.20107 Hs.657678 |
31 |
microtubule motor activity protein binding cytoplasm cytosol kinesin complex microtubule axon cargo transport axon cytoplasmic vesicle ciliary rootlet membrane-bounded organelle |
|
205710_at |
LRP2 |
low density lipoprotein-related protein 2 |
2 |
-169691864 |
NM_004525 |
4036 |
2q24-q31 |
Hs.657729 |
65 |
receptor activity calcium ion binding protein binding membrane fraction lysosome endosome endoplasmic reticulum Golgi apparatus brush border coated pit protein amino acid glycosylation lipid metabolic process vitamin metabolic process receptor-mediated endocytosis cell proliferation membrane integral to membrane apical plasma membrane SH3 domain binding endocytic vesicle forebrain development |
Hedgehog signaling pathway |
214787_at |
DENND4A |
DENN/MADD domain containing 4A |
15 |
-63740012 |
BE268538 |
10260 |
15q22.31 |
Hs.654567 |
8 |
DNA binding protein binding nucleus regulation of transcription, DNA-dependent |
|
208679_s_at |
ARPC2 |
actin related protein 2/3 complex, subunit 2, 34kDa |
2 |
218790118, 218790364 |
AF279893 |
10109 |
2q36.1 |
Hs.529303 |
23 |
actin binding structural constituent of cytoskeleton protein binding cytoplasm Golgi apparatus Arp2/3 protein complex focal adhesion cell motion positive regulation of actin filament polymerization cell leading edge cell projection |
Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
242146_at |
SNRPA1 |
small nuclear ribonucleoprotein polypeptide A' |
15 |
-99639237 |
AA872471 |
6627 |
15q26.3 |
Hs.528763 |
22 |
nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex U2 snRNP RNA splicing |
|
213116_at |
0.371 |
5.404 |
2.730 |
1.535e-02 |
0.457 |
-2.919 |
NEK3 |
NIMA (never in mitosis gene a)-related kinase 3 |
13 |
-51604780, -51604779, -51604779 |
AI191920 |
4752 |
13q14.13 |
Hs.409989 |
12 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation cell cycle mitosis transferase activity cell division |
|
222668_at |
1.150 |
4.264 |
4.284 |
6.335e-04 |
0.211 |
-0.216 |
KCTD15 |
potassium channel tetramerisation domain containing 15 |
19 |
38979590 |
W73820 |
79047 |
19q13.11 |
Hs.221873 Hs.606506 |
12 |
voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane |
|
223065_s_at |
0.367 |
7.615 |
2.494 |
2.459e-02 |
0.513 |
-3.316 |
STARD3NL |
STARD3 N-terminal like |
7 |
38184457 |
BC003074 |
83930 |
7p14-p13 |
Hs.309753 |
13 |
endosome membrane integral to membrane |
|
207956_x_at |
PDS5B |
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) |
13 |
32058591 |
NM_015928 |
23047 |
13q12.3 |
Hs.716441 |
15 |
chromatin DNA binding ATP binding nucleus cell cycle mitotic sister chromatid cohesion mitosis negative regulation of cell proliferation identical protein binding cell division |
|
222991_s_at |
UBQLN1 |
ubiquilin 1 |
9 |
-85464697 |
AL136643 |
29979 |
9q21.2-q21.3 9q22 |
Hs.9589 |
46 |
nucleus cytoplasm cytosol kinase binding protein complex perinuclear region of cytoplasm |
|
232704_s_at |
0.454 |
6.347 |
2.983 |
9.176e-03 |
0.400 |
-2.483 |
LRRFIP2 |
leucine rich repeat (in FLII) interacting protein 2 |
3 |
-37069120 |
AK025207 |
9209 |
3p22.2 |
Hs.719246 |
7 |
protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding |
|
1568834_s_at |
CCDC90B |
coiled-coil domain containing 90B |
11 |
-82650149 |
BC017771 |
60492 |
11q14.1 |
Hs.368866 |
7 |
mitochondrion membrane integral to membrane |
|
1560006_a_at |
LOC646762 |
hypothetical LOC646762 |
7 |
-29652063 |
BG501482 |
646762 |
7p14.3 |
Hs.30579 |
2 |
|
|
211063_s_at |
NCK1 |
NCK adaptor protein 1 |
3 |
138063762 |
BC006403 |
4690 |
3q21 |
Hs.477693 |
110 |
receptor binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal complex assembly cytoskeletal adaptor activity vesicle membrane cell migration protein domain specific binding lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation |
ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC |
216401_x_at |
LOC652493 |
similar to Ig kappa chain V-I region HK102 precursor |
Un |
|
AJ408433 |
652493 |
|
|
|
|
|
217550_at |
ATF6 |
activating transcription factor 6 |
1 |
160002707 |
AA576497 |
22926 |
1q22-q23 |
Hs.492740 |
43 |
transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity nucleus nuclear envelope nucleoplasm endoplasmic reticulum endoplasmic reticulum membrane regulation of transcription from RNA polymerase II promoter protein folding response to unfolded protein positive regulation of gene-specific transcription involved in unfolded protein response signal transduction membrane integral to membrane sequence-specific DNA binding protein dimerization activity |
Alzheimer's disease |
239654_at |
CHD9 |
chromodomain helicase DNA binding protein 9 |
16 |
51646445 |
T98846 |
80205 |
16q12.2 |
Hs.59159 Hs.622347 |
10 |
nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription |
|
236600_at |
SPG20 |
spastic paraplegia 20 (Troyer syndrome) |
13 |
-35773776, -35773776, -35773776 |
AI651603 |
23111 |
13q13.3 |
Hs.440414 |
19 |
cell death |
|
225009_at |
CMTM4 |
CKLF-like MARVEL transmembrane domain containing 4 |
16 |
-65206153 |
AA191708 |
146223 |
16q21-q22.1 |
Hs.643961 |
3 |
cytokine activity extracellular space chemotaxis membrane integral to membrane |
|
201590_x_at |
1.079 |
9.579 |
4.213 |
7.320e-04 |
0.211 |
-0.338 |
ANXA2 |
annexin A2 |
15 |
-58426642, -58426641 |
NM_004039 |
302 |
15q21-q22 |
Hs.511605 |
137 |
skeletal system development angiogenesis phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane soluble fraction cytoplasm early endosome cytoskeletal protein binding collagen fibril organization sarcolemma melanosome fibrinolysis protein complex perinuclear region of cytoplasm |
|
213427_at |
RPP40 |
ribonuclease P/MRP 40kDa subunit |
6 |
-4940278 |
NM_006638 |
10799 |
6p25.1 |
Hs.511756 |
4 |
ribonuclease P activity protein binding nucleus nucleolar ribonuclease P complex nucleolus tRNA processing hydrolase activity |
|
225244_at |
SNAP47 |
synaptosomal-associated protein, 47kDa |
1 |
225989319 |
AA019893 |
116841 |
1q42.13 |
Hs.325081 |
3 |
cytoplasm membrane perinuclear region of cytoplasm |
SNARE interactions in vesicular transport |
203411_s_at |
0.417 |
7.886 |
4.147 |
8.367e-04 |
0.216 |
-0.450 |
LMNA |
lamin A/C |
1 |
154351084, 154351084 |
NM_005572 |
4000 |
1q21.2-q21.3 |
Hs.594444 |
279 |
structural molecule activity protein binding nucleus cytoplasm intermediate filament plasma membrane |
Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
1559946_s_at |
0.466 |
8.615 |
2.858 |
1.185e-02 |
0.426 |
-2.700 |
RUVBL2 |
RuvB-like 2 (E. coli) |
19 |
54188967 |
AI860098 |
10856 |
19q13.3 |
Hs.515846 |
46 |
nucleotide binding damaged DNA binding ATP-dependent DNA helicase activity ATP binding intracellular nucleus nucleoplasm cytoplasm DNA repair DNA recombination protein folding membrane nuclear matrix chromatin modification hydrolase activity ATPase activity NuA4 histone acetyltransferase complex regulation of growth identical protein binding histone H4 acetylation histone H2A acetylation regulation of transcription unfolded protein binding |
|
204366_s_at |
GTF3C2 |
general transcription factor IIIC, polypeptide 2, beta 110kDa |
2 |
-27402224 |
NM_001521 |
2976 |
2p23.3 |
Hs.75782 |
18 |
transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity protein binding nucleus mitochondrion peroxisome transcription, DNA-dependent oxygen and reactive oxygen species metabolic process 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter |
|
203405_at |
PSMG1 |
proteasome (prosome, macropain) assembly chaperone 1 |
21 |
-39469253 |
NM_003720 |
8624 |
21q22.3 |
Hs.473838 |
12 |
protein binding cytoplasm endoplasmic reticulum proteasome assembly |
|
228506_at |
NSMCE4A |
non-SMC element 4 homolog A (S. cerevisiae) |
10 |
-123706592 |
AA009947 |
54780 |
10q26.13 |
Hs.258798 |
8 |
|
|
204392_at |
CAMK1 |
calcium/calmodulin-dependent protein kinase I |
3 |
-9774030 |
NM_003656 |
8536 |
3p25.3 |
Hs.434875 |
31 |
nucleotide binding calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm protein amino acid phosphorylation nucleocytoplasmic transport signal transduction multicellular organismal development nervous system development transferase activity cell differentiation |
|
227731_at |
CNBP |
CCHC-type zinc finger, nucleic acid binding protein |
3 |
-130369347 |
BF063728 |
7555 |
3q21 |
Hs.518249 |
24 |
transcription factor activity protein binding cytoplasm endoplasmic reticulum regulation of transcription, DNA-dependent cholesterol biosynthetic process zinc ion binding metal ion binding |
|
225049_at |
0.415 |
9.138 |
2.939 |
1.004e-02 |
0.414 |
-2.559 |
BLOC1S2 |
biogenesis of lysosomal organelles complex-1, subunit 2 |
10 |
-102023702, -102023702 |
BF382281 |
282991 |
10q24.31 |
Hs.34906 |
12 |
gamma-tubulin complex centrosome BLOC-1 complex melanosome organization identical protein binding regulation of apoptosis gamma-tubulin binding platelet dense granule organization |
|
201565_s_at |
ID2 |
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
2 |
8739563 |
NM_002166 |
3398 |
2p25 |
Hs.180919 |
76 |
negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleus cytoplasm multicellular organismal development heart development negative regulation of transcription transcription repressor activity enucleate erythrocyte differentiation negative regulation of transcription factor activity positive regulation of macrophage differentiation |
TGF-beta signaling pathway |
209107_x_at |
0.254 |
7.573 |
2.295 |
3.638e-02 |
0.559 |
-3.642 |
NCOA1 |
nuclear receptor coactivator 1 |
2 |
24660849 |
U19179 |
8648 |
2p23 |
Hs.596314 |
123 |
DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity nuclear hormone receptor binding positive regulation of transcription from RNA polymerase II promoter protein N-terminus binding androgen receptor binding |
|
215377_at |
CTBP2 |
C-terminal binding protein 2 |
10 |
-126666407, -126666407, -126666407 |
AK024129 |
1488 |
10q26.13 |
Hs.501345 |
32 |
nucleus negative regulation of cell proliferation oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor viral genome replication cell junction synapse cofactor binding NAD or NADH binding oxidation reduction |
Wnt signaling pathway Notch signaling pathway Pathways in cancer Chronic myeloid leukemia |
206284_x_at |
CLTB |
clathrin, light chain (Lcb) |
5 |
-175752061 |
NM_001834 |
1212 |
4q2-q3 5q35 |
Hs.484241 |
17 |
structural molecule activity calcium ion binding protein binding intracellular protein transport membrane vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle |
Lysosome Endocytosis Huntington's disease |
230049_at |
-0.272 |
4.975 |
-3.223 |
5.601e-03 |
0.354 |
-2.063 |
TAF6L |
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
11 |
62295450 |
AW303570 |
10629 |
11q12.3 |
Hs.714400 |
13 |
histone deacetylase complex DNA binding RNA polymerase II transcription factor activity transcription coactivator activity histone acetyltransferase activity protein binding nucleus chromatin remodeling transcription initiation regulation of transcription from RNA polymerase II promoter transcription initiation factor activity STAGA complex histone H3 acetylation regulation of transcription factor activity |
Basal transcription factors |
221535_at |
LSG1 |
large subunit GTPase 1 homolog (S. cerevisiae) |
3 |
-195842806 |
AL136897 |
55341 |
3q29 |
Hs.518505 |
12 |
nucleotide binding GTP binding intracellular nucleus cytoplasm endoplasmic reticulum Cajal body protein transport hydrolase activity nuclear export |
|
219500_at |
CLCF1 |
cardiotrophin-like cytokine factor 1 |
11 |
-66888214 |
NM_013246 |
23529 |
11q13.3 |
Hs.502977 |
13 |
cytokine activity extracellular region extracellular space JAK-STAT cascade growth factor activity cytokine-mediated signaling pathway B cell differentiation positive regulation of tyrosine phosphorylation of Stat3 protein negative regulation of apoptosis |
Cytokine-cytokine receptor interaction Jak-STAT signaling pathway |
224842_at |
SMG1 |
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) |
16 |
-18723676 |
AK025794 |
23049 |
16p12.3 |
Hs.460179 Hs.552700 |
23 |
nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm DNA repair mRNA export from nucleus response to DNA damage stimulus transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation manganese ion binding protein amino acid autophosphorylation phosphoinositide phosphorylation metal ion binding |
|
227091_at |
-0.440 |
4.776 |
-4.009 |
1.110e-03 |
0.228 |
-0.689 |
CCDC146 |
coiled-coil domain containing 146 |
7 |
76589869 |
AB040938 |
57639 |
7q11.23 |
Hs.113940 |
4 |
|
|
223046_at |
EGLN1 |
egl nine homolog 1 (C. elegans) |
1 |
-229566120 |
AL117352 |
54583 |
1q42.1 |
Hs.444450 Hs.710300 |
42 |
response to hypoxia embryonic placenta development iron ion binding protein binding cytosol heart development zinc ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding peptidyl-proline dioxygenase activity oxygen homeostasis negative regulation of transcription factor activity metal ion binding oxidation reduction |
Pathways in cancer Renal cell carcinoma |
208579_x_at |
0.635 |
5.642 |
4.345 |
5.600e-04 |
0.210 |
-0.113 |
H2BFS |
H2B histone family, member S |
21 |
|
NM_017445 |
54145 |
21q22.3 |
Hs.473961 |
17 |
nucleosome DNA binding nucleus chromosome nucleosome assembly defense response to bacterium |
|
219083_at |
0.397 |
7.144 |
2.841 |
1.226e-02 |
0.427 |
-2.729 |
SHQ1 |
SHQ1 homolog (S. cerevisiae) |
3 |
-72881117 |
NM_018130 |
55164 |
3p13 |
Hs.606584 |
2 |
|
|
201199_s_at |
0.417 |
9.140 |
3.103 |
7.174e-03 |
0.374 |
-2.274 |
PSMD1 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 |
2 |
231629852 |
NM_002807 |
5707 |
2q37.1 |
Hs.3887 |
43 |
proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
203688_at |
0.445 |
5.583 |
3.108 |
7.098e-03 |
0.372 |
-2.265 |
PKD2 |
polycystic kidney disease 2 (autosomal dominant) |
4 |
89147843 |
NM_000297 |
5311 |
4q21-q23 |
Hs.181272 |
82 |
kidney development embryonic placenta development polycystin complex receptor binding ion channel activity voltage-gated chloride channel activity voltage-gated sodium channel activity potassium channel activity calcium ion binding plasma membrane microtubule basal body cation transport calcium ion transport cellular calcium ion homeostasis cell cycle arrest cell-matrix adhesion JAK-STAT cascade determination of left/right symmetry heart development protein C-terminus binding cytoskeletal protein binding organ morphogenesis channel activity actin cytoskeleton integral to membrane regulation of cAMP metabolic process motile primary cilium nonmotile primary cilium detection of mechanical stimulus ATPase binding release of sequestered calcium ion into cytosol negative regulation of ryanodine-sensitive calcium-release channel activity |
|
210156_s_at |
PCMT1 |
protein-L-isoaspartate (D-aspartate) O-methyltransferase |
6 |
150112523 |
D25547 |
5110 |
6q24-q25 |
Hs.279257 |
25 |
protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding |
|
207543_s_at |
P4HA1 |
prolyl 4-hydroxylase, alpha polypeptide I |
10 |
-74436987 |
NM_000917 |
5033 |
10q21.3-q23.1 |
Hs.500047 Hs.593005 |
19 |
procollagen-proline 4-dioxygenase activity binding iron ion binding mitochondrion endoplasmic reticulum endoplasmic reticulum lumen oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction |
Arginine and proline metabolism Metabolic pathways |
211566_x_at |
0.480 |
7.654 |
3.966 |
1.212e-03 |
0.234 |
-0.763 |
BRE |
brain and reproductive organ-expressed (TNFRSF1A modulator) |
2 |
27966985, 27967060 |
U19178 |
9577 |
2p23.2 |
Hs.258314 |
20 |
nuclear ubiquitin ligase complex peroxisome targeting sequence binding tumor necrosis factor receptor binding protein binding nucleus cytoplasm double-strand break repair apoptosis response to DNA damage stimulus signal transduction response to ionizing radiation chromatin modification G2/M transition DNA damage checkpoint polyubiquitin binding positive regulation of DNA repair positive regulation of anti-apoptosis BRCA1-A complex BRISC complex |
|
232500_at |
C20orf74 |
chromosome 20 open reading frame 74 |
20 |
-20321410 |
AL121896 |
57186 |
20p11.22 |
Hs.472285 |
4 |
GTPase activator activity intracellular cytoplasm regulation of small GTPase mediated signal transduction |
|
200847_s_at |
TMEM66 |
transmembrane protein 66 |
8 |
-30040172 |
NM_016127 |
51669 |
8p12 |
Hs.521487 |
10 |
membrane integral to membrane |
|
233589_x_at |
C9orf167 |
chromosome 9 open reading frame 167 |
9 |
139292100 |
AK000392 |
54863 |
9q34.3 |
Hs.495541 |
1 |
nucleotide binding ATP binding endoplasmic reticulum membrane integral to membrane nucleoside-triphosphatase activity chaperone mediated protein folding requiring cofactor |
|
227027_at |
0.481 |
6.038 |
2.398 |
2.972e-02 |
0.536 |
-3.474 |
GFPT1 |
glutamine-fructose-6-phosphate transaminase 1 |
2 |
-69400408 |
AI268315 |
2673 |
2p13 |
Hs.580300 |
29 |
glutamine-fructose-6-phosphate transaminase (isomerizing) activity sugar binding cytoplasm fructose 6-phosphate metabolic process energy reserve metabolic process glutamine metabolic process metabolic process carbohydrate biosynthetic process transferase activity |
Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways |
201675_at |
-0.487 |
10.658 |
-3.058 |
7.876e-03 |
0.383 |
-2.353 |
AKAP1 |
A kinase (PRKA) anchor protein 1 |
17 |
52517551 |
NM_003488 |
8165 |
17q21-q23 |
Hs.463506 |
27 |
RNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane membrane integral to membrane |
|
238840_at |
LRRFIP1 |
leucine rich repeat (in FLII) interacting protein 1 |
2 |
238200962, 238265545, 238265545 |
AW082668 |
9208 |
2q37.3 |
Hs.471779 |
16 |
DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity |
|
204026_s_at |
0.439 |
4.881 |
3.407 |
3.834e-03 |
0.319 |
-1.741 |
ZWINT |
ZW10 interactor |
10 |
-57787204 |
NM_007057 |
11130 |
10q21-q22 |
Hs.591363 |
17 |
mitotic sister chromatid segregation condensed chromosome kinetochore nucleus cell cycle spindle organization mitotic cell cycle checkpoint protein N-terminus binding phosphoinositide-mediated signaling cell division establishment of localization in cell |
|
218177_at |
0.567 |
5.945 |
3.053 |
7.945e-03 |
0.384 |
-2.361 |
CHMP1B |
chromatin modifying protein 1B |
18 |
11841388 |
AA293502 |
57132 |
18p11.21 |
Hs.656244 |
16 |
cytoplasm endosome cytosol cell cycle protein transport membrane protein domain specific binding cell division |
Endocytosis |
205111_s_at |
0.831 |
4.732 |
3.408 |
3.828e-03 |
0.319 |
-1.739 |
PLCE1 |
phospholipase C, epsilon 1 |
10 |
95743735 |
NM_016341 |
51196 |
10q23 |
Hs.655033 |
35 |
Golgi membrane activation of MAPK activity regulation of cell growth phosphoinositide phospholipase C activity receptor signaling protein activity guanyl-nucleotide exchange factor activity calcium ion binding intracellular membrane fraction cytoplasm Golgi apparatus cytosol plasma membrane phospholipid metabolic process diacylglycerol biosynthetic process regulation of smooth muscle contraction cytoskeleton organization epidermal growth factor receptor signaling pathway activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway heart development regulation of G-protein coupled receptor protein signaling pathway cell proliferation lipid catabolic process hydrolase activity Ras GTPase binding calcium-mediated signaling calcium-mediated signaling enzyme binding glomerulus development regulation of protein kinase activity regulation of Ras protein signal transduction inositol phosphate-mediated signaling |
Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system |
237257_at |
-0.371 |
7.260 |
-2.655 |
1.784e-02 |
0.475 |
-3.046 |
RAB4B |
RAB4B, member RAS oncogene family |
19 |
45976010 |
AI668580 |
53916 |
19q13.2 |
Hs.631539 |
5 |
nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport |
|
216942_s_at |
0.343 |
5.244 |
2.390 |
3.021e-02 |
0.540 |
-3.487 |
CD58 |
CD58 molecule |
1 |
-116862845, -116858679 |
D28586 |
965 |
1p13 |
Hs.34341 |
38 |
protein binding plasma membrane integral to plasma membrane cell-cell adhesion anchored to membrane |
Cell adhesion molecules (CAMs) |
229969_at |
SEC63 |
SEC63 homolog (S. cerevisiae) |
6 |
-108295652 |
AV723931 |
11231 |
6q21 |
Hs.26904 |
14 |
receptor activity endoplasmic reticulum protein folding protein targeting to membrane protein transport membrane integral to membrane heat shock protein binding unfolded protein binding |
|
209217_s_at |
WDR45 |
WD repeat domain 45 |
X |
-48819035, -48819035 |
BC000464 |
11152 |
Xp11.23 |
Hs.632807 |
8 |
|
|
241959_at |
ANAPC10 |
anaphase promoting complex subunit 10 |
4 |
-146135759 |
AW025455 |
10393 |
4q31 |
Hs.480876 |
21 |
G2/M transition of mitotic cell cycle mitotic anaphase ubiquitin-protein ligase activity protein binding nucleoplasm anaphase-promoting complex cytosol ubiquitin-dependent protein catabolic process cell cycle regulation of mitotic metaphase/anaphase transition anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
224720_at |
MIB1 |
mindbomb homolog 1 (Drosophila) |
18 |
17575542 |
AW243097 |
57534 |
18q11.2 |
Hs.140903 Hs.658808 |
15 |
blood vessel development in utero embryonic development somitogenesis neural tube formation heart looping ubiquitin-protein ligase activity protein binding cytoplasm plasma membrane Notch signaling pathway heart development zinc ion binding protein ubiquitination ligase activity modification-dependent protein catabolic process cytoplasmic vesicle negative regulation of neuron differentiation positive regulation of endocytosis metal ion binding |
|
228845_at |
0.255 |
6.076 |
2.842 |
1.222e-02 |
0.427 |
-2.726 |
PLBD2 |
phospholipase B domain containing 2 |
12 |
112280753 |
AW451356 |
196463 |
12q24.13 |
Hs.115896 |
4 |
lipid catabolic process hydrolase activity lysosomal lumen |
|
201449_at |
TIA1 |
TIA1 cytotoxic granule-associated RNA binding protein |
2 |
-70290079 |
AL567227 |
7072 |
2p13 |
Hs.413123 |
34 |
nucleotide binding RNA binding protein binding apoptosis induction of apoptosis poly(A) RNA binding |
|
226470_at |
GGT7 |
gamma-glutamyltransferase 7 |
20 |
-32896183 |
AL049709 |
2686 |
20q11.22 |
Hs.433738 |
9 |
gamma-glutamyltransferase activity glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity |
Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways |
219377_at |
FAM59A |
family with sequence similarity 59, member A |
18 |
-28101474 |
NM_022751 |
64762 |
18q12.1 |
Hs.444314 |
7 |
|
|
227511_at |
SAMD4B |
sterile alpha motif domain containing 4B |
19 |
44524947 |
BE963280 |
55095 |
19q13.2 |
Hs.612332 |
8 |
protein binding |
|
231849_at |
0.663 |
3.849 |
2.545 |
2.226e-02 |
0.500 |
-3.232 |
KRT80 |
keratin 80 |
12 |
-50849046 |
AL162069 |
144501 |
12q13.13 |
Hs.140978 |
3 |
structural molecule activity keratin filament |
|
205309_at |
SMPDL3B |
sphingomyelin phosphodiesterase, acid-like 3B |
1 |
28134090, 28134090 |
NM_014474 |
27293 |
1p35.3 |
Hs.123659 |
3 |
sphingomyelin phosphodiesterase activity extracellular region extracellular space sphingomyelin catabolic process metabolic process hydrolase activity, acting on glycosyl bonds |
|
201471_s_at |
0.264 |
9.615 |
2.190 |
4.452e-02 |
0.580 |
-3.809 |
SQSTM1 |
sequestosome 1 |
5 |
179165993, 179166608, 179180447 |
NM_003900 |
8878 |
5q35 |
Hs.437277 |
100 |
protein kinase C binding protein binding nucleus cytoplasm late endosome cytosol cytosol ubiquitin-dependent protein catabolic process apoptosis response to stress immune response intracellular signaling cascade protein localization zinc ion binding endosome transport cell differentiation receptor tyrosine kinase binding SH2 domain binding SH2 domain binding regulation of I-kappaB kinase/NF-kappaB cascade regulation of I-kappaB kinase/NF-kappaB cascade ubiquitin binding ubiquitin binding positive regulation of transcription from RNA polymerase II promoter metal ion binding |
|
1553874_a_at |
-0.263 |
4.069 |
-2.519 |
2.344e-02 |
0.507 |
-3.275 |
ZSCAN10 |
zinc finger and SCAN domain containing 10 |
16 |
-3078895 |
NM_032805 |
84891 |
16p13.3 |
Hs.334515 |
4 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
206283_s_at |
TAL1 |
T-cell acute lymphocytic leukemia 1 |
1 |
-47454549 |
NM_003189 |
6886 |
1p32 |
Hs.705618 Hs.709194 |
65 |
DNA binding protein binding nucleus multicellular organismal development cell proliferation cell differentiation transcription regulator activity regulation of transcription |
|
1567250_at |
OR10A3 |
olfactory receptor, family 10, subfamily A, member 3 |
11 |
-7916698 |
X64986 |
26496 |
11p15.4 |
Hs.381322 |
5 |
receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus |
Olfactory transduction |
224616_at |
0.309 |
9.374 |
3.063 |
7.793e-03 |
0.381 |
-2.344 |
DYNC1LI2 |
dynein, cytoplasmic 1, light intermediate chain 2 |
16 |
-65312299 |
BG110975 |
1783 |
16q22.1 |
Hs.369068 |
10 |
nucleotide binding motor activity ATP binding cytoplasmic dynein complex microtubule |
|
1555942_a_at |
LOC642587 |
NPC-A-5 |
1 |
207668790 |
AK091113 |
642587 |
1q32.2 |
Hs.510543 |
2 |
|
|
205902_at |
KCNN3 |
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 |
1 |
-152946536, -152946536 |
AJ251016 |
3782 |
1q21.3 |
Hs.490765 |
40 |
ion channel activity calmodulin binding ion transport potassium ion transport membrane integral to membrane small conductance calcium-activated potassium channel activity |
|
1557165_s_at |
0.579 |
8.697 |
2.415 |
2.879e-02 |
0.534 |
-3.447 |
KLHL18 |
kelch-like 18 (Drosophila) |
3 |
47299333 |
BM141828 |
23276 |
3p21.31 |
Hs.517946 |
8 |
protein binding |
|
204633_s_at |
0.600 |
6.956 |
2.289 |
3.682e-02 |
0.561 |
-3.652 |
RPS6KA5 |
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
14 |
-90430071, -90406922 |
AF074393 |
9252 |
14q31-q32.1 |
Hs.510225 |
47 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-dependent response to stress epidermal growth factor receptor signaling pathway protein kinase cascade response to external stimulus histone phosphorylation transferase activity response to chemical stimulus |
MAPK signaling pathway Neurotrophin signaling pathway Bladder cancer |
201914_s_at |
SEC63 |
SEC63 homolog (S. cerevisiae) |
6 |
-108295652 |
AK001465 |
11231 |
6q21 |
Hs.26904 |
14 |
receptor activity endoplasmic reticulum protein folding protein targeting to membrane protein transport membrane integral to membrane heat shock protein binding unfolded protein binding |
|
220248_x_at |
0.278 |
9.150 |
2.764 |
1.432e-02 |
0.447 |
-2.861 |
NSFL1C |
NSFL1 (p97) cofactor (p47) |
20 |
-1370810 |
NM_018839 |
55968 |
20p13 |
Hs.12865 |
20 |
protein binding nucleus Golgi apparatus Golgi stack lipid binding |
|
1552789_at |
SEC62 |
SEC62 homolog (S. cerevisiae) |
3 |
171167273 |
NM_153039 |
7095 |
3q26.2 |
Hs.622596 |
10 |
receptor activity endoplasmic reticulum cytoskeleton cotranslational protein targeting to membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport |
|
213860_x_at |
0.373 |
8.864 |
2.251 |
3.960e-02 |
0.568 |
-3.712 |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
AW268585 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
228248_at |
RICTOR |
RPTOR independent companion of MTOR, complex 2 |
5 |
-38973779 |
W49629 |
253260 |
5p13.1 |
Hs.407926 |
21 |
guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade |
mTOR signaling pathway |
208877_at |
PAK2 |
p21 protein (Cdc42/Rac)-activated kinase 2 |
3 |
197951124 |
W74494 |
5062 |
3q29 |
Hs.518530 |
80 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol negative regulation of protein kinase activity apoptosis signal transduction membrane transferase activity regulation of growth identical protein binding interspecies interaction between organisms protein amino acid autophosphorylation perinuclear region of cytoplasm |
MAPK signaling pathway ErbB signaling pathway Axon guidance Focal adhesion T cell receptor signaling pathway Regulation of actin cytoskeleton Renal cell carcinoma |
215554_at |
GPLD1 |
glycosylphosphatidylinositol specific phospholipase D1 |
6 |
-24581304, -24536383 |
AV699786 |
2822 |
6p22.3-p22.2 |
Hs.533291 |
26 |
glycosylphosphatidylinositol phospholipase D activity extracellular region hydrolase activity |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
201867_s_at |
0.350 |
3.416 |
3.040 |
8.165e-03 |
0.387 |
-2.384 |
TBL1X |
transducin (beta)-like 1X-linked |
X |
9391334, 9393200 |
AW968555 |
6907 |
Xp22.3 |
Hs.495656 |
16 |
nucleus signal transduction visual perception sensory perception of sound modification-dependent protein catabolic process regulation of transcription |
Wnt signaling pathway |
201857_at |
ZFR |
zinc finger RNA binding protein |
5 |
-32390212 |
NM_016107 |
51663 |
5p13.3 |
Hs.435231 |
6 |
DNA binding RNA binding intracellular nucleus nucleolus cytoplasm multicellular organismal development zinc ion binding |
|
201862_s_at |
LRRFIP1 |
leucine rich repeat (in FLII) interacting protein 1 |
2 |
238200962, 238265545, 238265545 |
NM_004735 |
9208 |
2q37.3 |
Hs.471779 |
16 |
DNA binding double-stranded RNA binding protein binding nucleus cytoplasm cytoskeleton regulation of transcription from RNA polymerase II promoter negative regulation of transcription transcription repressor activity |
|
202723_s_at |
0.793 |
6.727 |
4.627 |
3.178e-04 |
0.179 |
0.360 |
FOXO1 |
forkhead box O1 |
13 |
-40027800 |
AW117498 |
2308 |
13q14.1 |
Hs.370666 |
140 |
blood vessel development transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent anti-apoptosis insulin receptor signaling pathway transcription activator activity regulation of cell proliferation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter |
Insulin signaling pathway Pathways in cancer Prostate cancer |
208872_s_at |
0.645 |
8.350 |
2.518 |
2.345e-02 |
0.507 |
-3.276 |
REEP5 |
receptor accessory protein 5 |
5 |
-112239979 |
AA814140 |
7905 |
5q22-q23 |
Hs.429608 |
11 |
molecular_function protein binding biological_process membrane integral to membrane |
|
205248_at |
-0.625 |
5.898 |
-2.409 |
2.910e-02 |
0.535 |
-3.456 |
DOPEY2 |
dopey family member 2 |
21 |
36458708 |
NM_005128 |
9980 |
21q22.2 |
Hs.204575 |
12 |
Golgi membrane molecular_function Golgi to endosome transport endoplasmic reticulum organization multicellular organismal development protein transport |
|
1557170_at |
-0.277 |
5.687 |
-2.876 |
1.141e-02 |
0.426 |
-2.668 |
NEK8 |
NIMA (never in mitosis gene a)- related kinase 8 |
17 |
24079958 |
AI073943 |
284086 |
17q11.1 |
Hs.448468 |
8 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
232844_at |
IFT140 |
intraflagellar transport 140 homolog (Chlamydomonas) |
16 |
-1500429 |
AU159127 |
9742 |
16p13.3 |
Hs.389438 |
6 |
|
|
203590_at |
0.237 |
7.840 |
2.411 |
2.898e-02 |
0.534 |
-3.453 |
DYNC1LI2 |
dynein, cytoplasmic 1, light intermediate chain 2 |
16 |
-65312299 |
NM_006141 |
1783 |
16q22.1 |
Hs.369068 |
10 |
nucleotide binding motor activity ATP binding cytoplasmic dynein complex microtubule |
|
237284_at |
DNAJB8 |
DnaJ (Hsp40) homolog, subfamily B, member 8 |
3 |
-129663971 |
AI188219 |
165721 |
3q21.3 |
Hs.518241 |
3 |
heat shock protein binding |
|
1553935_at |
-0.224 |
2.672 |
-2.508 |
2.393e-02 |
0.509 |
-3.293 |
MGC2848 |
hypothetical protein MGC2848 |
3 |
|
NM_032917 |
85003 |
3q22.1 |
Hs.435710 |
1 |
|
|
227736_at |
C10orf99 |
chromosome 10 open reading frame 99 |
10 |
85923533 |
AA553959 |
387695 |
10q23.1 |
Hs.298713 |
1 |
extracellular region |
|
1554634_at |
PDS5B |
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) |
13 |
32058591 |
BC039256 |
23047 |
13q12.3 |
Hs.716441 |
15 |
chromatin DNA binding ATP binding nucleus cell cycle mitotic sister chromatid cohesion mitosis negative regulation of cell proliferation identical protein binding cell division |
|
235297_at |
CUGBP1 |
CUG triplet repeat, RNA binding protein 1 |
11 |
-47446520, -47446520, -47446520 |
BG286365 |
10658 |
11p11 |
Hs.632137 |
34 |
nucleotide binding translation repressor activity, nucleic acid binding mRNA binding nucleus cytoplasm mRNA splice site selection mRNA processing germ cell development embryonic development RNA interference ribonucleoprotein complex BRE binding |
|
227714_s_at |
C9orf86 |
chromosome 9 open reading frame 86 |
9 |
138822201 |
AI971522 |
55684 |
9q34.3 |
Hs.370555 |
11 |
nucleotide binding protein binding GTP binding nucleus cytoplasm small GTPase mediated signal transduction |
|
219237_s_at |
DNAJB14 |
DnaJ (Hsp40) homolog, subfamily B, member 14 |
4 |
-101039734 |
NM_024920 |
79982 |
4q23 |
Hs.577426 |
6 |
protein folding membrane integral to membrane heat shock protein binding unfolded protein binding |
|
225242_s_at |
1.396 |
5.742 |
4.494 |
4.144e-04 |
0.192 |
0.139 |
CCDC80 |
coiled-coil domain containing 80 |
3 |
-113806098 |
AW303375 |
151887 |
3q13.2 |
Hs.477128 |
10 |
fibronectin binding extracellular region basement membrane interstitial matrix heparin binding positive regulation of cell-substrate adhesion extracellular matrix organization intracellular membrane-bounded organelle |
|
220407_s_at |
0.398 |
4.017 |
2.285 |
3.706e-02 |
0.562 |
-3.657 |
TGFB2 |
transforming growth factor, beta 2 |
1 |
216586013 |
NM_003238 |
7042 |
1q41 |
Hs.133379 |
112 |
cell morphogenesis skeletal system development cartilage condensation angiogenesis beta-amyloid binding blood vessel development eye development response to hypoxia blood vessel remodeling receptor signaling protein serine/threonine kinase activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding cytokine activity extracellular region extracellular region extracellular region extracellular space induction of apoptosis activation-induced cell death of T cells cell cycle arrest transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation cell-cell signaling axon guidance salivary gland morphogenesis growth factor activity cell death positive regulation of cell proliferation glial cell migration embryonic development positive regulation of epithelial cell migration negative regulation of alkaline phosphatase activity positive regulation of epithelial to mesenchymal transition positive regulation of phosphoinositide 3-kinase cascade menstrual cycle phase hemopoiesis collagen fibril organization positive regulation of cell growth negative regulation of cell growth axon neutrophil chemotaxis neutrophil chemotaxis extracellular matrix hair follicle morphogenesis platelet alpha granule lumen activation of protein kinase activity response to progesterone stimulus positive regulation of stress-activated MAPK cascade regulation of transforming growth factor-beta2 production positive regulation of cell adhesion mediated by integrin wound healing dopamine biosynthetic process odontogenesis protein homodimerization activity cell soma positive regulation of neuron apoptosis cell-cell junction organization positive regulation of integrin biosynthetic process positive regulation of ossification positive regulation of cell cycle positive regulation of heart contraction protein heterodimerization activity somatic stem cell division neuron fate commitment neuron development generation of neurons negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive regulation of protein secretion negative regulation of immune response positive regulation of immune response positive regulation of catagen positive regulation of cardioblast differentiation cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition pathway-restricted SMAD protein phosphorylation |
MAPK signaling pathway Cytokine-cytokine receptor interaction Cell cycle TGF-beta signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hypertrophic cardiomyopathy (HCM) |
233191_at |
RUFY2 |
RUN and FYVE domain containing 2 |
10 |
-69806955, -69773280 |
AB040970 |
55680 |
10q21.3 |
Hs.653144 |
5 |
nucleus zinc ion binding metal ion binding |
|
235343_at |
0.766 |
3.146 |
2.495 |
2.456e-02 |
0.513 |
-3.314 |
VASH2 |
vasohibin 2 |
1 |
211190509 |
AI961235 |
79805 |
1q32.3 |
Hs.96885 |
5 |
|
|
210732_s_at |
0.750 |
2.848 |
3.914 |
1.348e-03 |
0.245 |
-0.853 |
LGALS8 |
lectin, galactoside-binding, soluble, 8 |
1 |
234748187, 234753361, 234753699 |
AF342816 |
3964 |
1q42-q43 |
Hs.4082 Hs.708114 |
29 |
sugar binding extracellular space cytoplasm |
|
225674_at |
BCAP29 |
B-cell receptor-associated protein 29 |
7 |
107007657, 107008439 |
AW873330 |
55973 |
7q22-q31 |
Hs.303787 |
12 |
endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport |
|
204722_at |
0.915 |
6.199 |
2.601 |
1.989e-02 |
0.491 |
-3.137 |
SCN3B |
sodium channel, voltage-gated, type III, beta |
11 |
-123005104 |
AW007335 |
55800 |
11q23.3 |
Hs.4865 |
19 |
voltage-gated ion channel activity voltage-gated sodium channel activity plasma membrane ion transport sodium ion transport integral to membrane sodium ion binding |
|
41387_r_at |
-0.261 |
6.770 |
-2.168 |
4.644e-02 |
0.582 |
-3.843 |
KDM6B |
lysine (K)-specific demethylase 6B |
17 |
7683959 |
AB002344 |
23135 |
17p13.1 |
Hs.223678 |
8 |
negative regulation of transcription from RNA polymerase II promoter binding iron ion binding nucleus inflammatory response oxidoreductase activity chromatin modification histone demethylation oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen sequence-specific DNA binding metal ion binding oxidation reduction |
|
205389_s_at |
ANK1 |
ankyrin 1, erythrocytic |
8 |
-41629901, -41629901, -41629900 |
AI659683 |
286 |
8p11.1 |
Hs.654438 Hs.667377 |
49 |
structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity |
|
211780_x_at |
DCTN1 |
dynactin 1 (p150, glued homolog, Drosophila) |
2 |
-74441789, -74441789 |
BC006163 |
1639 |
2p13 |
Hs.516111 |
74 |
spindle pole motor activity protein binding cytoplasm cytoskeleton microtubule mitosis nervous system development cell death dynein complex |
Huntington's disease |
203137_at |
WTAP |
Wilms tumor 1 associated protein |
6 |
160068141, 160068141, 160068609 |
NM_004906 |
9589 |
6q25-q27 |
Hs.446091 Hs.710715 |
16 |
nucleus nucleolus mRNA processing cell cycle RNA splicing nuclear membrane |
|
1552344_s_at |
CNOT7 |
CCR4-NOT transcription complex, subunit 7 |
8 |
-17133392, -17131110 |
NM_054026 |
29883 |
8p22-p21.3 |
Hs.645009 Hs.719129 |
19 |
nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
RNA degradation |
213970_at |
RABL3 |
RAB, member of RAS oncogene family-like 3 |
3 |
-121888217 |
AA744682 |
285282 |
3q13.33 |
Hs.444360 |
1 |
nucleotide binding GTP binding intracellular small GTPase mediated signal transduction |
|
208042_at |
AGGF1 |
angiogenic factor with G patch and FHA domains 1 |
5 |
76361987 |
NM_013303 |
55109 |
5q13.3 |
Hs.634849 |
12 |
vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm |
|
225081_s_at |
-0.614 |
5.590 |
-2.254 |
3.935e-02 |
0.567 |
-3.707 |
CDCA7L |
cell division cycle associated 7-like |
7 |
-21907042 |
AK022955 |
55536 |
7p15.3 |
Hs.520245 Hs.655326 |
15 |
nucleus cytoplasm regulation of transcription |
|
236813_at |
0.619 |
5.600 |
4.206 |
7.419e-04 |
0.211 |
-0.349 |
MORN4 |
MORN repeat containing 4 |
10 |
-99364299, -99364299 |
N21659 |
118812 |
10q24.2 |
Hs.217409 |
6 |
|
|
213467_at |
RND2 |
Rho family GTPase 2 |
17 |
38430783 |
BF511718 |
8153 |
17q21 |
Hs.603111 |
16 |
nucleotide binding GTPase activity protein binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction |
|
207851_s_at |
0.289 |
4.924 |
2.184 |
4.499e-02 |
0.581 |
-3.817 |
INSR |
insulin receptor |
19 |
-7063265 |
NM_000208 |
3643 |
19p13.3-p13.2 |
Hs.465744 |
351 |
nucleotide binding activation of MAPK activity positive regulation of protein amino acid phosphorylation heart morphogenesis receptor signaling protein tyrosine kinase activity receptor activity insulin receptor activity insulin-like growth factor receptor binding ATP binding GTP binding endosome microsome cytosol plasma membrane plasma membrane insulin receptor complex caveola carbohydrate metabolic process G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation positive regulation of cell proliferation insulin receptor signaling pathway endosome membrane transferase activity peptidyl-tyrosine phosphorylation transformation of host cell by virus protein phosphatase binding male sex determination positive regulation of cell migration insulin-like growth factor I binding insulin-like growth factor II binding activation of protein kinase B activity regulation of gene-specific transcription SH2 domain binding glucose homeostasis positive regulation of MAPKKK cascade 3-phosphoinositide-dependent protein kinase binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of nitric oxide biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of DNA replication positive regulation of glycolysis positive regulation of mitosis regulation of embryonic development positive regulation of glucose import positive regulation of glucose import protein amino acid autophosphorylation positive regulation of developmental growth protein heterotetramerization PTB domain binding positive regulation of protein kinase B signaling cascade positive regulation of respiratory burst |
Adherens junction Insulin signaling pathway Type II diabetes mellitus |
212947_at |
SLC9A8 |
solute carrier family 9 (sodium/hydrogen exchanger), member 8 |
20 |
47862656 |
AL031685 |
23315 |
20q13.13 |
Hs.444202 |
12 |
Golgi apparatus cation transport sodium ion transport regulation of pH antiporter activity solute:hydrogen antiporter activity sodium:hydrogen antiporter activity membrane integral to membrane sodium ion binding |
|
207148_x_at |
MYOZ2 |
myozenin 2 |
4 |
120276386 |
NM_016599 |
51778 |
4q26-q27 |
Hs.381047 |
16 |
protein binding cytoplasm biological_process actin cytoskeleton sarcomere Z disc protein phosphatase 2B binding |
|
219027_s_at |
MYO9A |
myosin IXA |
15 |
-69905414 |
NM_006901 |
4649 |
15q22-q23 |
Hs.546268 |
8 |
nucleotide binding motor activity actin binding GTPase activator activity protein binding ATP binding intracellular intracellular signaling cascade visual perception zinc ion binding membrane integral to membrane myosin complex diacylglycerol binding metal ion binding |
|
227930_at |
EIF2C4 |
eukaryotic translation initiation factor 2C, 4 |
1 |
36046414 |
AI669957 |
192670 |
1p34.3 |
Hs.471492 |
8 |
cytoplasmic mRNA processing body RNA binding protein binding cytoplasm mRNA catabolic process regulation of translation gene silencing by RNA gene silencing by miRNA, negative regulation of translation |
|
217969_at |
C11orf2 |
chromosome 11 open reading frame 2 |
11 |
64620258 |
NM_013265 |
738 |
11q13 |
Hs.277517 |
6 |
molecular_function Golgi apparatus lipid transport biological_process protein transport integral to membrane |
|
232194_at |
METTL4 |
methyltransferase like 4 |
18 |
-2527523 |
AA764787 |
64863 |
18p11.32 |
Hs.126888 |
4 |
nucleic acid binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process methyltransferase activity transferase activity methylation |
|
204545_at |
-1.236 |
5.578 |
-3.338 |
4.426e-03 |
0.330 |
-1.863 |
PEX6 |
peroxisomal biogenesis factor 6 |
6 |
-43039588 |
NM_000287 |
5190 |
6p21.1 |
Hs.656425 |
20 |
nucleotide binding ATP binding cytoplasm peroxisome peroxisomal membrane cytosol protein targeting to peroxisome protein C-terminus binding membrane protein import into peroxisome matrix, translocation protein complex binding ATPase activity, coupled protein stabilization |
|
232609_at |
CRB3 |
crumbs homolog 3 (Drosophila) |
19 |
6415259 |
BC002652 |
92359 |
19p13.3 |
Hs.150319 |
11 |
plasma membrane tight junction integral to membrane cell junction |
Tight junction |
207457_s_at |
LY6G6D |
lymphocyte antigen 6 complex, locus G6D |
6 |
31791111, 3129252, 2930718 |
NM_021246 |
58530 |
6p21.3 |
Hs.591792 |
2 |
protein binding cytosol plasma membrane defense response response to unfolded protein response to nutrient anchored to membrane protein complex NF-kappaB binding |
|
200789_at |
ECH1 |
enoyl Coenzyme A hydratase 1, peroxisomal |
19 |
-43997901 |
NM_001398 |
1891 |
19q13.1 |
Hs.196176 |
9 |
enoyl-CoA hydratase activity protein binding mitochondrion peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation metabolic process isomerase activity |
Tyrosine metabolism |
208997_s_at |
UCP2 |
uncoupling protein 2 (mitochondrial, proton carrier) |
11 |
-73363363 |
U82819 |
7351 |
11q13 |
Hs.80658 |
153 |
response to superoxide binding mitochondrion mitochondrial inner membrane transport mitochondrial transport proton transport membrane integral to membrane |
|
214890_s_at |
2.248 |
5.468 |
6.943 |
4.362e-06 |
0.039 |
3.757 |
FAM149A |
family with sequence similarity 149, member A |
4 |
187302988, 187307320 |
AL080065 |
25854 |
4q35.1 |
Hs.357025 |
3 |
|
|
201898_s_at |
UBE2A |
ubiquitin-conjugating enzyme E2A (RAD6 homolog) |
X |
118592526, 118598325 |
AI126625 |
7319 |
Xq24-q25 |
Hs.379466 |
16 |
nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination |
Ubiquitin mediated proteolysis |
204066_s_at |
AGAP1 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
2 |
236067474 |
NM_014914 |
116987 |
2q37 |
Hs.435039 |
11 |
nucleotide binding GTP binding intracellular cytoplasm small GTPase mediated signal transduction ARF GTPase activator activity zinc ion binding protein transport regulation of ARF GTPase activity metal ion binding |
Endocytosis |
213251_at |
SMARCA5 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
4 |
144654065 |
AV712064 |
8467 |
4q31.1-q31.2 |
Hs.558422 Hs.710623 |
37 |
nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling |
|
222611_s_at |
0.606 |
5.386 |
3.336 |
4.437e-03 |
0.330 |
-1.865 |
PSPC1 |
paraspeckle component 1 |
13 |
-19175008, -19146895 |
AA969958 |
55269 |
13q12.11 |
Hs.213198 |
9 |
nucleotide binding RNA binding protein binding nucleus nucleolus cytoplasm nuclear matrix regulation of transcription |
|
204173_at |
MYL6B |
myosin, light chain 6B, alkali, smooth muscle and non-muscle |
12 |
54832601 |
NM_002475 |
140465 |
12q13.13 |
Hs.632731 |
8 |
motor activity calcium ion binding protein binding muscle myosin complex skeletal muscle tissue development structural constituent of muscle unconventional myosin complex muscle filament sliding |
|
228613_at |
RAB11FIP3 |
RAB11 family interacting protein 3 (class II) |
16 |
415668, 464850 |
BF183535 |
9727 |
16p13.3 |
Hs.531642 |
18 |
calcium ion binding protein binding protein transport membrane Rab GTPase binding recycling endosome |
Endocytosis |
201096_s_at |
0.329 |
7.868 |
2.841 |
1.227e-02 |
0.427 |
-2.729 |
ARF4 |
ADP-ribosylation factor 4 |
3 |
-57532129 |
AL537042 |
378 |
3p21.2-p21.1 |
Hs.695943 |
19 |
nucleotide binding GTPase activity GTP binding intracellular cytoplasm Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport vesicle-mediated transport |
|
202972_s_at |
FAM13A |
family with sequence similarity 13, member A |
4 |
-89866128, -89866128 |
AW450403 |
10144 |
4q22.1 |
Hs.97270 |
7 |
|
|
214429_at |
MTMR6 |
myotubularin related protein 6 |
13 |
-24718340 |
U47635 |
9107 |
13q12 |
Hs.643702 |
17 |
protein serine/threonine phosphatase activity protein tyrosine phosphatase activity cellular_component nucleus nuclear envelope cytoplasm protein amino acid dephosphorylation calcium-activated potassium channel activity hydrolase activity phosphatase activity |
Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways |
225421_at |
PM20D2 |
peptidase M20 domain containing 2 |
6 |
89912487 |
AI654133 |
135293 |
6q15 |
Hs.709364 |
2 |
proteolysis metallopeptidase activity hydrolase activity protein dimerization activity |
|
204076_at |
ENTPD4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
8 |
-23345516, -23345516 |
AB002390 |
9583 |
8p21.3-p21.2 |
Hs.444389 |
8 |
magnesium ion binding calcium ion binding Golgi apparatus UDP catabolic process membrane integral to membrane hydrolase activity integral to Golgi membrane cytoplasmic vesicle uridine-diphosphatase activity |
Purine metabolism Pyrimidine metabolism Lysosome |
218908_at |
0.478 |
5.716 |
2.673 |
1.722e-02 |
0.471 |
-3.016 |
ASPSCR1 |
alveolar soft part sarcoma chromosome region, candidate 1 |
17 |
77528714 |
NM_024083 |
79058 |
17q25.3 |
Hs.298351 |
11 |
molecular_function protein binding cellular_component biological_process membrane |
|
228947_x_at |
TMEM204 |
transmembrane protein 204 |
16 |
1524231 |
AW612362 |
79652 |
16p13.3 |
Hs.459652 |
7 |
plasma membrane adherens junction response to stress integral to membrane cell junction |
|
1553177_at |
SH2D1B |
SH2 domain containing 1B |
1 |
-160631679 |
BC022407 |
117157 |
1q23.3 |
Hs.350581 |
10 |
molecular_function protein binding cellular_component biological_process |
Natural killer cell mediated cytotoxicity |
205383_s_at |
0.344 |
8.745 |
2.843 |
1.220e-02 |
0.426 |
-2.725 |
ZBTB20 |
zinc finger and BTB domain containing 20 |
3 |
-115540212 |
NM_015642 |
26137 |
3q13.2 |
Hs.655108 |
13 |
DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding |
|
224937_at |
0.874 |
4.284 |
3.442 |
3.567e-03 |
0.312 |
-1.679 |
PTGFRN |
prostaglandin F2 receptor negative regulator |
1 |
117254211 |
BF311866 |
5738 |
1p13.1 |
Hs.418093 |
14 |
protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane |
|
224371_at |
-0.247 |
4.366 |
-3.206 |
5.806e-03 |
0.357 |
-2.094 |
ADAMTSL1 |
ADAMTS-like 1 |
9 |
18464103, 18464103 |
AF251058 |
92949 |
9p22.2-p22.1 |
Hs.522019 |
10 |
extracellular region proteinaceous extracellular matrix peptidase activity metallopeptidase activity zinc ion binding |
|
204306_s_at |
0.570 |
7.177 |
3.618 |
2.480e-03 |
0.287 |
-1.370 |
CD151 |
CD151 molecule (Raph blood group) |
11 |
822951 |
NM_004357 |
977 |
11p15.5 |
Hs.654379 |
55 |
protein binding membrane fraction plasma membrane integral to plasma membrane cell adhesion |
|
217047_s_at |
FAM13A |
family with sequence similarity 13, member A |
4 |
-89866128, -89866128 |
AK027138 |
10144 |
4q22.1 |
Hs.97270 |
7 |
|
|
223479_s_at |
CHCHD5 |
coiled-coil-helix-coiled-coil-helix domain containing 5 |
2 |
113058506 |
BC004498 |
84269 |
2q13 |
Hs.375707 |
3 |
|
|
212328_at |
LIMCH1 |
LIM and calponin homology domains 1 |
4 |
41057560, 41309675 |
AB029025 |
22998 |
4p13 |
Hs.335163 |
10 |
actin binding zinc ion binding actomyosin structure organization metal ion binding |
|
203675_at |
NUCB2 |
nucleobindin 2 |
11 |
17254861 |
NM_005013 |
4925 |
11p15.1-p14 |
Hs.654599 |
15 |
DNA binding calcium ion binding extracellular region extracellular space nucleus nuclear outer membrane cytoplasm endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus cytosol plasma membrane |
|
215022_x_at |
0.554 |
3.269 |
3.430 |
3.656e-03 |
0.314 |
-1.700 |
ZNF33B |
zinc finger protein 33B |
10 |
-42404560 |
BG429214 |
7582 |
10q11.2 |
Hs.499453 |
9 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
201419_at |
BAP1 |
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
3 |
-52410064 |
NM_004656 |
8314 |
3p21.31-p21.2 |
Hs.106674 |
16 |
ubiquitin thiolesterase activity protein binding intracellular nucleus protein modification process ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity negative regulation of cell proliferation |
|
48808_at |
0.734 |
6.165 |
2.214 |
4.251e-02 |
0.575 |
-3.771 |
DHFR |
dihydrofolate reductase |
5 |
-79957800 |
AI144299 |
1719 |
5q11.2-q13.2 |
Hs.592364 Hs.648635 |
80 |
dihydrofolate reductase activity cellular_component glycine biosynthetic process one-carbon metabolic process nucleotide biosynthetic process oxidoreductase activity NADP or NADPH binding oxidation reduction |
One carbon pool by folate Folate biosynthesis Biosynthesis of phenylpropanoids Metabolic pathways |
207289_at |
MMP25 |
matrix metallopeptidase 25 |
16 |
3036682 |
NM_004142 |
64386 |
16p13.3 |
Hs.654979 |
16 |
metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix plasma membrane proteolysis inflammatory response metabolic process peptidase activity zinc ion binding cell surface anchored to membrane |
|
204595_s_at |
STC1 |
stanniocalcin 1 |
8 |
-23755378 |
AI300520 |
6781 |
8p21-p11.2 |
Hs.25590 |
35 |
hormone activity extracellular region extracellular space cellular calcium ion homeostasis cell surface receptor linked signal transduction cell-cell signaling response to nutrient |
|
226445_s_at |
0.398 |
7.086 |
4.032 |
1.058e-03 |
0.226 |
-0.648 |
TRIM41 |
tripartite motif-containing 41 |
5 |
180582911 |
AI743109 |
90933 |
5q35.3 |
Hs.441488 |
9 |
protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding |
|
202984_s_at |
BAG5 |
BCL2-associated athanogene 5 |
14 |
-103092641, -103092641, -103092641 |
AA457021 |
9529 |
14q32.33 |
Hs.5443 |
10 |
protein binding protein folding apoptosis |
|
221854_at |
PKP1 |
plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) |
1 |
199519202 |
AI378979 |
5317 |
1q32 |
Hs.497350 |
26 |
signal transducer activity protein binding nucleus intermediate filament cell adhesion signal transduction multicellular organismal development intermediate filament binding cell junction desmosome structural constituent of epidermis |
|
209075_s_at |
-0.338 |
11.329 |
-2.840 |
1.227e-02 |
0.427 |
-2.730 |
ISCU |
iron-sulfur cluster scaffold homolog (E. coli) |
12 |
107480423 |
AY009128 |
23479 |
12q24.1 |
Hs.615131 |
14 |
iron ion binding nucleus cytoplasm mitochondrion cytosol nitrogen fixation iron-sulfur cluster assembly protein complex scaffold metal ion binding iron-sulfur cluster binding |
|
1558762_a_at |
-0.247 |
5.053 |
-2.447 |
2.702e-02 |
0.525 |
-3.394 |
ZNF789 |
zinc finger protein 789 |
7 |
98908450, 98908450 |
AK093141 |
285989 |
7q22.1 |
Hs.440384 |
4 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
217187_at |
-0.395 |
6.696 |
-2.600 |
1.992e-02 |
0.491 |
-3.139 |
MUC5AC |
mucin 5AC, oligomeric mucus/gel-forming |
11 |
1132473 |
Z34282 |
4586 |
11p15.5 |
Hs.534332 Hs.558950 |
95 |
molecular_function protein binding extracellular region apoptosis induction of apoptosis cell adhesion digestion biological_process negative regulation of cell proliferation extracellular matrix constituent, lubricant activity negative regulation of cell migration fibril fibril organization |
|
229711_s_at |
MDM2 |
Mdm2 p53 binding protein homolog (mouse) |
12 |
67488237, 67489063 |
AA902480 |
4193 |
12q14.3-q15 |
Hs.484551 |
555 |
negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter p53 binding ubiquitin-protein ligase activity intracellular insoluble fraction nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol protein complex assembly zinc ion binding positive regulation of cell proliferation ligase activity basal transcription repressor activity basal transcription repressor activity enzyme binding modification-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process identical protein binding interspecies interaction between organisms metal ion binding |
Cell cycle p53 signaling pathway Ubiquitin mediated proteolysis Endocytosis Pathways in cancer Glioma Prostate cancer Melanoma Bladder cancer Chronic myeloid leukemia |
231015_at |
KLF15 |
Kruppel-like factor 15 |
3 |
-127544167 |
AW014734 |
28999 |
3q13-q21 |
Hs.272215 |
10 |
transcription factor activity protein binding intracellular nucleus zinc ion binding glucose transport regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding |
|
230683_at |
0.425 |
3.848 |
3.680 |
2.184e-03 |
0.276 |
-1.262 |
ANKRD60 |
ankyrin repeat domain 60 |
20 |
|
W56760 |
140731 |
20q13.32 |
|
1 |
|
|
232035_at |
HIST1H4B |
histone cluster 1, H4b |
6 |
-26135102 |
BE740761 |
8366 |
6p21.3 |
Hs.143080 |
9 |
|
Systemic lupus erythematosus |
214264_s_at |
0.521 |
4.440 |
2.408 |
2.919e-02 |
0.535 |
-3.459 |
C14orf143 |
chromosome 14 open reading frame 143 |
14 |
-89333221 |
AI656610 |
90141 |
14q32.11 |
Hs.123232 |
2 |
calcium ion binding |
|
1555522_s_at |
MEMO1 |
mediator of cell motility 1 |
2 |
-31946398, -31946397 |
BC036262 |
51072 |
2p22-p21 |
Hs.444969 |
10 |
nucleus cytosol |
|
225747_at |
COQ10A |
coenzyme Q10 homolog A (S. cerevisiae) |
12 |
54946908, 54947333 |
AL521634 |
93058 |
12q13.3 |
Hs.4096 |
5 |
mitochondrion |
|
235446_at |
XIST |
X (inactive)-specific transcript (non-protein coding) |
X |
-72957219 |
AW856618 |
7503 |
Xq13.2 |
Hs.529901 |
21 |
|
|
242586_at |
FSD1L |
fibronectin type III and SPRY domain containing 1-like |
9 |
107250135, 107250135, 107250145 |
H07986 |
83856 |
9q31 |
Hs.136901 |
4 |
molecular_function cellular_component biological_process |
|
208804_s_at |
0.322 |
8.152 |
2.297 |
3.623e-02 |
0.558 |
-3.638 |
SFRS6 |
splicing factor, arginine/serine-rich 6 |
20 |
41519917 |
AL031681 |
6431 |
20q12-q13.1 |
Hs.6891 |
31 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus mRNA splice site selection RNA splicing |
|
243916_x_at |
UBLCP1 |
ubiquitin-like domain containing CTD phosphatase 1 |
5 |
158622666 |
H73636 |
134510 |
5q33.3 |
Hs.591733 |
7 |
phosphoprotein phosphatase activity nucleus hydrolase activity |
|
226629_at |
SLC43A2 |
solute carrier family 43, member 2 |
17 |
-1424445 |
AI742770 |
124935 |
17p13.3 |
Hs.160550 |
3 |
plasma membrane transport L-amino acid transmembrane transporter activity L-amino acid transport integral to membrane |
|
228559_at |
CENPN |
centromere protein N |
16 |
79597603, 79597603, 79597603 |
BF111626 |
55839 |
16q23.2 |
Hs.55028 |
9 |
chromosome, centromeric region condensed chromosome kinetochore nucleus chromosome |
|
200610_s_at |
NCL |
nucleolin |
2 |
-232027702 |
NM_005381 |
4691 |
2q12-qter |
Hs.79110 |
97 |
nucleotide binding angiogenesis DNA binding RNA binding nucleus nucleolus cell cortex protein C-terminus binding ribonucleoprotein complex telomeric DNA binding |
Pathogenic Escherichia coli infection - EHEC |
228077_at |
0.472 |
7.456 |
2.578 |
2.084e-02 |
0.497 |
-3.177 |
MRI1 |
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae) |
19 |
13736336 |
AK026666 |
84245 |
19p13.2 |
Hs.439370 |
11 |
cellular amino acid biosynthetic process methionine biosynthetic process isomerase activity identical protein binding cellular biosynthetic process S-methyl-5-thioribose-1-phosphate isomerase activity |
|
214252_s_at |
0.558 |
5.333 |
3.535 |
2.943e-03 |
0.298 |
-1.515 |
CLN5 |
ceroid-lipofuscinosis, neuronal 5 |
13 |
76464059 |
AV700514 |
1203 |
13q21.1-q32 |
Hs.30213 |
19 |
protein binding lysosomal membrane vacuolar lumen endoplasmic reticulum Golgi apparatus lysosomal lumen acidification brain development visual perception integral to membrane integral to membrane neurogenesis protein catabolic process neuron maturation perinuclear region of cytoplasm |
Lysosome |
223143_s_at |
0.801 |
5.361 |
3.135 |
6.719e-03 |
0.367 |
-2.218 |
AKIRIN2 |
akirin 2 |
6 |
-88441298 |
AI742378 |
55122 |
6q15 |
Hs.485915 |
10 |
protein binding nucleus embryonic development transcriptional repressor complex response to lipopolysaccharide positive regulation of interleukin-6 production innate immune response regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
|
209394_at |
0.386 |
5.788 |
2.191 |
4.439e-02 |
0.580 |
-3.806 |
ASMTL |
acetylserotonin O-methyltransferase-like |
X, Y |
-1482031, -1482031 |
BC002508 |
8623 |
Xp22.3 Yp11.3 |
Hs.533514 |
10 |
cellular_component cytoplasm acetylserotonin O-methyltransferase activity melatonin biosynthetic process |
|
226277_at |
COL4A3BP |
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
5 |
-74702683, -74702683 |
AA889952 |
10087 |
5q13.3 |
Hs.270437 |
26 |
protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response |
|
1569629_x_at |
-0.254 |
4.124 |
-3.319 |
4.594e-03 |
0.333 |
-1.895 |
LOC389906 |
similar to Serine/threonine-protein kinase PRKX (Protein kinase PKX1) |
X |
|
BC017231 |
389906 |
Xp22.33 |
Hs.636199 Hs.684492 |
1 |
|
|
242422_at |
0.544 |
4.508 |
3.028 |
8.376e-03 |
0.388 |
-2.406 |
G3BP1 |
GTPase activating protein (SH3 domain) binding protein 1 |
5 |
151131668 |
AA180161 |
10146 |
5q33.1 |
Hs.587054 |
27 |
nucleotide binding DNA binding RNA binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity helicase activity endonuclease activity protein binding ATP binding intracellular nucleus cytoplasm cytosol plasma membrane transport Ras protein signal transduction hydrolase activity |
|
214622_at |
-0.272 |
5.161 |
-2.253 |
3.944e-02 |
0.567 |
-3.709 |
CYP21A2 |
cytochrome P450, family 21, subfamily A, polypeptide 2 |
6 |
32114060, 3413239, 3221082 |
M17252 |
1589 |
6p21.3 |
Hs.654479 |
185 |
monooxygenase activity steroid 21-monooxygenase activity steroid binding endoplasmic reticulum microsome C21-steroid hormone biosynthetic process electron carrier activity membrane heme binding metal ion binding oxidation reduction |
C21-Steroid hormone metabolism Metabolic pathways |
230150_at |
0.377 |
5.665 |
2.628 |
1.885e-02 |
0.488 |
-3.092 |
BCAP29 |
B-cell receptor-associated protein 29 |
7 |
107007657, 107008439 |
N57499 |
55973 |
7q22-q31 |
Hs.303787 |
12 |
endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport |
|
1569610_at |
IQCH |
IQ motif containing H |
15 |
65334241, 65334247 |
BC039463 |
64799 |
15q23 |
Hs.657894 |
5 |
|
|
1569594_a_at |
SDCCAG1 |
serologically defined colon cancer antigen 1 |
14 |
-49320281 |
BC006001 |
9147 |
14q22 |
Hs.655964 |
8 |
nucleus cytoplasm |
|
234727_at |
-0.250 |
3.198 |
-2.161 |
4.704e-02 |
0.584 |
-3.854 |
DNAH7 |
dynein, axonemal, heavy chain 7 |
2 |
-196310671 |
Z83801 |
56171 |
2q32.3 |
Hs.97403 |
6 |
nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme |
|
235174_s_at |
0.415 |
8.397 |
2.438 |
2.749e-02 |
0.526 |
-3.409 |
LOC100128822 |
hypothetical LOC100128822 |
7 |
151792141 |
AW952781 |
100128822 |
7q36.1 |
Hs.647112 |
2 |
|
|
239898_x_at |
-0.266 |
5.538 |
-2.343 |
3.311e-02 |
0.551 |
-3.564 |
ZNF286A |
zinc finger protein 286A |
17 |
15543615 |
AI498484 |
57335 |
17p11.2 |
Hs.585799 Hs.659318 |
7 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
244523_at |
0.484 |
5.944 |
2.548 |
2.211e-02 |
0.499 |
-3.226 |
MMD |
monocyte to macrophage differentiation-associated |
17 |
-50824972 |
AW104453 |
23531 |
17q |
Hs.463483 Hs.656753 |
4 |
receptor activity membrane fraction lysosome endosome integral to plasma membrane membrane cytolysis |
|
201641_at |
BST2 |
bone marrow stromal cell antigen 2 |
19 |
-17374754 |
NM_004335 |
684 |
19p13.2 |
Hs.118110 |
20 |
signal transducer activity Golgi apparatus plasma membrane integral to plasma membrane humoral immune response cell-cell signaling multicellular organismal development cell proliferation response to virus anchored to membrane B cell activation positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
206692_at |
-0.301 |
2.995 |
-2.864 |
1.171e-02 |
0.426 |
-2.690 |
KCNJ10 |
potassium inwardly-rectifying channel, subfamily J, member 10 |
1 |
-158274656 |
NM_002241 |
3766 |
1q22-q23 |
Hs.408960 |
25 |
nucleotide binding voltage-gated ion channel activity potassium channel activity protein binding ATP binding integral to plasma membrane ion transport potassium ion transport ATP-activated inward rectifier potassium channel activity membrane potassium ion binding |
|
218025_s_at |
PECI |
peroxisomal D3,D2-enoyl-CoA isomerase |
6 |
-4060925 |
NM_006117 |
10455 |
6p24.3 |
Hs.15250 |
15 |
acyl-CoA binding dodecenoyl-CoA delta-isomerase activity binding peroxisome peroxisomal matrix fatty acid metabolic process metabolic process isomerase activity |
Fatty acid metabolism |
211004_s_at |
ALDH3B1 |
aldehyde dehydrogenase 3 family, member B1 |
11 |
67532623, 67534365 |
BC002553 |
221 |
11q13 |
Hs.523841 |
10 |
3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase [NAD(P)+] activity alcohol metabolic process cellular aldehyde metabolic process lipid metabolic process oxidoreductase activity oxidation reduction |
Glycolysis / Gluconeogenesis Histidine metabolism Tyrosine metabolism Phenylalanine metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways |
1553486_a_at |
-0.268 |
3.136 |
-2.806 |
1.317e-02 |
0.433 |
-2.789 |
C17orf78 |
chromosome 17 open reading frame 78 |
17 |
32807097 |
NM_173625 |
284099 |
17q12 |
Hs.439154 |
2 |
membrane integral to membrane |
|
1564637_a_at |
FAM98B |
family with sequence similarity 98, member B |
15 |
36533619, 36533619 |
BC035600 |
283742 |
15q14 |
Hs.6799 |
5 |
protein binding |
|
243256_at |
0.408 |
5.437 |
3.938 |
1.284e-03 |
0.240 |
-0.812 |
MKNK1 |
MAP kinase interacting serine/threonine kinase 1 |
1 |
-46795677 |
AW796364 |
8569 |
1p33 |
Hs.371594 |
28 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm regulation of translation protein amino acid phosphorylation response to stress protein kinase cascade transferase activity |
MAPK signaling pathway Insulin signaling pathway |
224840_at |
0.979 |
10.230 |
3.255 |
5.248e-03 |
0.348 |
-2.008 |
FKBP5 |
FK506 binding protein 5 |
6 |
-35656311, -35649339, -35649339, -35649339 |
AI753747 |
2289 |
6p21.3-p21.2 |
Hs.407190 |
50 |
peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding |
|
236876_at |
H1FNT |
H1 histone family, member N, testis-specific |
12 |
47009029 |
AW013835 |
341567 |
12q13.11 |
Hs.155833 |
3 |
nucleotide binding nuclear chromatin DNA binding ATP binding nucleus chromosome multicellular organismal development spermatogenesis spermatid nucleus elongation cell differentiation chromosome condensation sperm chromatin condensation |
|
213435_at |
SATB2 |
SATB homeobox 2 |
2 |
-199842468 |
AB028957 |
23314 |
2q33 |
Hs.516617 |
9 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
226595_at |
0.348 |
6.249 |
3.573 |
2.720e-03 |
0.290 |
-1.448 |
SNX21 |
sorting nexin family member 21 |
20 |
43895876 |
AI935964 |
90203 |
20q13.12 |
Hs.472854 |
8 |
protein binding cell communication protein transport phosphoinositide binding |
|
202779_s_at |
0.841 |
5.832 |
3.171 |
6.241e-03 |
0.362 |
-2.155 |
UBE2S |
ubiquitin-conjugating enzyme E2S |
19 |
-60604461 |
NM_014501 |
27338 |
19q13.43 |
Hs.396393 |
6 |
nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
236061_at |
PRDM15 |
PR domain containing 15 |
21 |
-42094393, -42091453 |
BF058757 |
63977 |
21q22.3 |
Hs.473893 Hs.711654 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
221528_s_at |
ELMO2 |
engulfment and cell motility 2 |
20 |
-44428096 |
BC000143 |
63916 |
20q13 |
Hs.210469 |
16 |
binding cytoplasm cytoskeleton phagocytosis apoptosis SH3 domain binding |
|
218181_s_at |
0.318 |
6.902 |
2.290 |
3.673e-02 |
0.560 |
-3.650 |
MAP4K4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
2 |
101680919 |
NM_017792 |
9448 |
2q11.2-q12 |
Hs.719073 |
22 |
nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade transferase activity |
MAPK signaling pathway |
212676_at |
NF1 |
neurofibromin 1 |
17 |
26446120, 26446120 |
AW293356 |
4763 |
17q11.2 |
Hs.113577 |
204 |
osteoblast differentiation metanephros development response to hypoxia liver development negative regulation of endothelial cell proliferation regulation of cell-matrix adhesion Ras GTPase activator activity protein binding intracellular nucleus cytoplasm signal transduction Ras protein signal transduction negative regulation of neuroblast proliferation brain development peripheral nervous system development heart development visual learning phosphoinositide 3-kinase cascade spinal cord development forebrain astrocyte development cerebral cortex development myelination in the peripheral nervous system actin cytoskeleton organization collagen fibril organization adrenal gland development negative regulation of cell migration axon dendrite positive regulation of Ras GTPase activity wound healing negative regulation of transcription factor import into nucleus negative regulation of MAP kinase activity negative regulation of MAPKKK cascade pigmentation positive regulation of neuron apoptosis regulation of blood vessel endothelial cell migration regulation of bone resorption regulation of glial cell differentiation positive regulation of adenylate cyclase activity regulation of angiogenesis sympathetic nervous system development camera-type eye morphogenesis negative regulation of oligodendrocyte differentiation smooth muscle tissue development artery morphogenesis forebrain morphogenesis cognition regulation of small GTPase mediated signal transduction |
MAPK signaling pathway |
208920_at |
0.444 |
5.198 |
2.860 |
1.180e-02 |
0.426 |
-2.697 |
SRI |
sorcin |
7 |
-87672367, -87672367 |
AV752215 |
6717 |
7q21.1 |
Hs.489040 |
28 |
regulation of action potential receptor binding calcium channel regulator activity calcium ion binding cytoplasm transport intracellular sequestering of iron ion regulation of striated muscle contraction signal transduction heart development muscle organ development regulation of heart contraction |
|
226395_at |
HOOK3 |
hook homolog 3 (Drosophila) |
8 |
42871189 |
AI912618 |
84376 |
8p11.21 |
Hs.162852 |
13 |
cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex |
|
223880_x_at |
C20orf24 |
chromosome 20 open reading frame 24 |
20 |
34667580, 34667605 |
BC004446 |
55969 |
20q11.23 |
Hs.584985 |
7 |
molecular_function protein binding cellular_component biological_process |
|
208744_x_at |
0.272 |
6.312 |
2.228 |
4.135e-02 |
0.571 |
-3.748 |
HSPH1 |
heat shock 105kDa/110kDa protein 1 |
13 |
-30608762 |
BG403660 |
10808 |
13q12.3 |
Hs.36927 |
25 |
nucleotide binding ATP binding cytoplasm response to unfolded protein |
|
225579_at |
0.651 |
6.230 |
3.870 |
1.474e-03 |
0.250 |
-0.929 |
PQLC3 |
PQ loop repeat containing 3 |
2 |
11212990 |
AL516202 |
130814 |
2p25.1 |
Hs.274415 |
5 |
membrane integral to membrane |
|
1569097_at |
TP53BP1 |
tumor protein p53 binding protein 1 |
15 |
-41486705, -41486705 |
BU508386 |
7158 |
15q15-q21 |
Hs.440968 |
80 |
condensed chromosome kinetochore damaged DNA binding protein binding intracellular nucleus nucleoplasm nucleoplasm replication fork cytoplasm DNA repair response to DNA damage stimulus transcription activator activity telomeric DNA binding regulation of transcription positive regulation of transcription, DNA-dependent |
|
212061_at |
SR140 |
U2-associated SR140 protein |
3 |
144203061 |
AB002330 |
23350 |
3q23 |
Hs.596572 |
4 |
nucleotide binding RNA binding RNA processing |
|
214526_x_at |
PMS2L1 |
postmeiotic segregation increased 2-like 1 pseudogene |
7 |
-99756198 |
NM_005394 |
5379 |
7q22.1 |
Hs.634244 Hs.661055 Hs.709266 |
7 |
molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding |
|
231600_at |
-0.182 |
2.078 |
-2.157 |
4.744e-02 |
0.585 |
-3.861 |
CLEC12B |
C-type lectin domain family 12, member B |
12 |
10054497, 10054497 |
AI657064 |
387837 |
12p13.2 |
Hs.127937 |
3 |
receptor activity binding sugar binding plasma membrane integral to membrane |
|
209001_s_at |
ANAPC13 |
anaphase promoting complex subunit 13 |
3 |
-135679236, -135679236, -135679236 |
BC005398 |
25847 |
3q22.2 |
Hs.106909 |
6 |
nucleus cell cycle mitosis modification-dependent protein catabolic process cell division |
Cell cycle Ubiquitin mediated proteolysis |
238615_at |
-0.271 |
2.866 |
-3.268 |
5.106e-03 |
0.346 |
-1.984 |
ERLIN2 |
ER lipid raft associated 2 |
8 |
37713254, 37713254, 37713356 |
AI817403 |
11160 |
8p11.2 |
Hs.705490 |
13 |
molecular_function cytoplasm endoplasmic reticulum endoplasmic reticulum membrane biological_process membrane integral to membrane |
|
1569677_a_at |
-0.312 |
2.454 |
-3.454 |
3.483e-03 |
0.309 |
-1.659 |
C8orf45 |
chromosome 8 open reading frame 45 |
8 |
67945537, 67945537, 67946290 |
BC034576 |
157777 |
8q13.1 |
Hs.437006 |
2 |
|
|
209939_x_at |
0.583 |
8.223 |
2.530 |
2.291e-02 |
0.503 |
-3.256 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AF005775 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
232518_at |
PRIC285 |
peroxisomal proliferator-activated receptor A interacting complex 285 |
20 |
-61659882, -61659882 |
AL121829 |
85441 |
20q13.33 |
Hs.517180 |
9 |
nucleotide binding DNA binding transcription coactivator activity RNA binding helicase activity ribonuclease activity ATP binding intracellular nucleus zinc ion binding hydrolase activity regulation of transcription metal ion binding |
|
214646_at |
-0.302 |
4.847 |
-3.333 |
4.471e-03 |
0.331 |
-1.872 |
HIST1H3J |
histone cluster 1, H3j |
6 |
-27966071 |
AL522145 |
8356 |
6p22-p21.3 |
Hs.484990 |
8 |
|
Systemic lupus erythematosus |
217487_x_at |
-0.250 |
5.313 |
-2.381 |
3.073e-02 |
0.542 |
-3.502 |
FOLH1 |
folate hydrolase (prostate-specific membrane antigen) 1 |
11 |
-49124762 |
AF254357 |
2346 |
11p11.2 |
Hs.654487 |
86 |
carboxypeptidase activity membrane fraction cytoplasm plasma membrane integral to plasma membrane proteolysis peptidase activity metallopeptidase activity zinc ion binding dipeptidase activity metal ion binding |
|
229439_s_at |
-0.260 |
5.334 |
-2.138 |
4.918e-02 |
0.590 |
-3.890 |
RBM47 |
RNA binding motif protein 47 |
4 |
-40120028, -40120028 |
AI830823 |
54502 |
4p13-p12 |
Hs.518727 |
4 |
RNA binding nucleus |
|
205975_s_at |
-0.344 |
4.748 |
-2.533 |
2.278e-02 |
0.502 |
-3.251 |
HOXD1 |
homeobox D1 |
2 |
176761552 |
NM_024501 |
3231 |
2q31.1 |
Hs.83465 |
14 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding |
|
215075_s_at |
GRB2 |
growth factor receptor-bound protein 2 |
17 |
-70825751, -70825751 |
L29511 |
2885 |
17q24-q25 |
Hs.444356 Hs.708119 |
438 |
SH3/SH2 adaptor activity epidermal growth factor receptor binding Golgi apparatus cytosol cytosol epidermal growth factor receptor signaling pathway Ras protein signal transduction Ras protein signal transduction cell-cell signaling insulin receptor signaling pathway insulin receptor substrate binding interspecies interaction between organisms |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
234947_s_at |
C10orf84 |
chromosome 10 open reading frame 84 |
10 |
-120058561 |
AK026630 |
63877 |
10q26.11 |
Hs.372309 |
5 |
|
|
225889_at |
0.339 |
6.137 |
2.443 |
2.721e-02 |
0.526 |
-3.400 |
AEBP2 |
AE binding protein 2 |
12 |
19483874 |
BF475280 |
121536 |
12p12.3 |
Hs.126497 |
5 |
DNA binding transcription corepressor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding chromatin modification metal ion binding |
|
207001_x_at |
0.577 |
6.615 |
3.521 |
3.029e-03 |
0.300 |
-1.540 |
TSC22D3 |
TSC22 domain family, member 3 |
X |
-106843107, -106843107, -106843107 |
NM_004089 |
1831 |
Xq22.3 |
Hs.716410 |
24 |
transcription factor activity regulation of transcription, DNA-dependent |
|
214074_s_at |
0.302 |
5.140 |
2.192 |
4.432e-02 |
0.579 |
-3.805 |
CTTN |
cortactin |
11 |
69922259, 69922291 |
BG475299 |
2017 |
11q13 |
Hs.596164 |
106 |
ruffle protein binding soluble fraction cytoplasm cytoskeleton cell cortex lamellipodium |
Tight junction Pathogenic Escherichia coli infection - EHEC |
235520_at |
0.510 |
3.502 |
3.194 |
5.954e-03 |
0.357 |
-2.115 |
ZNF280C |
zinc finger protein 280C |
X |
-129164362 |
AA805654 |
55609 |
Xq26.1 |
Hs.308418 |
4 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
227523_s_at |
0.402 |
6.197 |
3.014 |
8.603e-03 |
0.391 |
-2.428 |
PHF20L1 |
PHD finger protein 20-like 1 |
8 |
133856785, 133856785, 133856785 |
AA192936 |
51105 |
8q24.22 |
Hs.304362 |
4 |
nucleic acid binding protein binding zinc ion binding metal ion binding |
|
1553015_a_at |
-0.244 |
6.144 |
-2.142 |
4.878e-02 |
0.590 |
-3.883 |
RECQL4 |
RecQ protein-like 4 |
8 |
-145707478 |
NM_004260 |
9401 |
8q24.3 |
Hs.31442 |
38 |
nucleotide binding bubble DNA binding DNA strand renaturation DNA strand annealing activity nucleic acid binding DNA helicase activity ATP binding nucleus cytoplasm DNA repair DNA recombination multicellular organismal development ATP-dependent helicase activity zinc ion binding hydrolase activity DNA duplex unwinding ATP-dependent 3'-5' DNA helicase activity |
|
207403_at |
IRS4 |
insulin receptor substrate 4 |
X |
-107862382 |
NM_003604 |
8471 |
Xq22.3 |
Hs.460872 |
21 |
SH3/SH2 adaptor activity insulin receptor binding protein binding plasma membrane signal transduction |
Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus |
209339_at |
-0.304 |
5.908 |
-2.802 |
1.327e-02 |
0.435 |
-2.796 |
SIAH2 |
seven in absentia homolog 2 (Drosophila) |
3 |
-151941599 |
U76248 |
6478 |
3q25 |
Hs.477959 Hs.692394 |
34 |
transcription corepressor activity ubiquitin-protein ligase activity protein binding nucleus cytoplasm ubiquitin-dependent protein catabolic process apoptosis cell cycle small GTPase mediated signal transduction multicellular organismal development zinc ion binding protein ubiquitination ligase activity metal ion binding |
|
207797_s_at |
0.424 |
4.932 |
3.371 |
4.130e-03 |
0.323 |
-1.804 |
LRP2BP |
LRP2 binding protein |
4 |
-186522026 |
NM_018409 |
55805 |
4q35.1 |
Hs.558513 |
4 |
protein binding cytoplasm |
|
241425_at |
NUPL1 |
nucleoporin like 1 |
13 |
24773665 |
AA769986 |
9818 |
13q12.13 |
Hs.310453 Hs.719291 |
9 |
nucleus nuclear pore protein transport membrane mRNA transport intracellular protein transmembrane transport |
|
1560633_a_at |
D21S2089E |
D21S2089E |
21 |
|
AY063453 |
246312 |
21q21.1 |
Hs.473425 |
1 |
|
|
220757_s_at |
UBXN6 |
UBX domain protein 6 |
19 |
-4396260 |
NM_025241 |
80700 |
19p13 |
Hs.435255 Hs.661664 |
6 |
molecular_function protein binding cellular_component nucleus cytoplasm centrosome biological_process modification-dependent protein catabolic process |
|
224767_at |
0.292 |
6.011 |
3.083 |
7.482e-03 |
0.376 |
-2.310 |
RPL37 |
ribosomal protein L37 |
5 |
-40867186 |
AL044126 |
6167 |
5p13 |
Hs.558601 Hs.80545 |
12 |
structural constituent of ribosome protein binding intracellular cytosol ribosome translational elongation zinc ion binding rRNA binding cytosolic large ribosomal subunit metal ion binding |
Ribosome |
1556588_at |
C15orf37 |
chromosome 15 open reading frame 37 |
15 |
78002167 |
AK091107 |
283687 |
15q25.1 |
Hs.512015 |
2 |
|
|
232591_s_at |
0.285 |
3.859 |
2.313 |
3.507e-02 |
0.555 |
-3.612 |
TMEM30A |
transmembrane protein 30A |
6 |
-76019357 |
AK022883 |
55754 |
6q14.1 |
Hs.108530 |
7 |
membrane integral to membrane |
|
218595_s_at |
HEATR1 |
HEAT repeat containing 1 |
1 |
-234780593 |
NM_018072 |
55127 |
1q43 |
Hs.708114 |
9 |
protein binding nucleus nucleolus rRNA processing ribonucleoprotein complex |
|
205755_at |
ITIH3 |
inter-alpha (globulin) inhibitor H3 |
3 |
52803823 |
NM_002217 |
3699 |
3p21.2-p21.1 |
Hs.76716 |
24 |
serine-type endopeptidase inhibitor activity extracellular region hyaluronan metabolic process |
|
1552727_s_at |
ADAMTS17 |
ADAM metallopeptidase with thrombospondin type 1 motif, 17 |
15 |
-98329165 |
AA022668 |
170691 |
15q24 |
Hs.513200 |
5 |
metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding |
|
206516_at |
-0.309 |
4.538 |
-2.531 |
2.288e-02 |
0.503 |
-3.255 |
AMH |
anti-Mullerian hormone |
19 |
2200112 |
NM_000479 |
268 |
19p13.3 |
Hs.112432 |
75 |
urogenital system development Mullerian duct regression transforming growth factor beta receptor binding hormone activity extracellular region extracellular space cytoplasm cell-cell signaling gonadal mesoderm development sex determination sex differentiation growth factor activity cell differentiation |
Cytokine-cytokine receptor interaction TGF-beta signaling pathway |
227476_at |
0.342 |
6.861 |
2.230 |
4.124e-02 |
0.571 |
-3.745 |
LPGAT1 |
lysophosphatidylglycerol acyltransferase 1 |
1 |
-209983422 |
AW576195 |
9926 |
1q32 |
Hs.497674 |
6 |
molecular_function cytoplasm endoplasmic reticulum metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity |
|
1552362_a_at |
-0.439 |
6.237 |
-3.962 |
1.222e-03 |
0.234 |
-0.770 |
LEAP2 |
liver expressed antimicrobial peptide 2 |
5 |
132237256 |
NM_052971 |
116842 |
5q31.1 |
Hs.337588 |
3 |
extracellular region defense response to bacterium |
|
212551_at |
CAP2 |
CAP, adenylate cyclase-associated protein, 2 (yeast) |
6 |
17501714 |
NM_006366 |
10486 |
6p22.3 |
Hs.132902 |
7 |
actin binding binding plasma membrane cytoskeleton organization establishment or maintenance of cell polarity signal transduction activation of adenylate cyclase activity |
|
201674_s_at |
-0.423 |
10.078 |
-2.629 |
1.882e-02 |
0.488 |
-3.091 |
AKAP1 |
A kinase (PRKA) anchor protein 1 |
17 |
52517551 |
BC000729 |
8165 |
17q21-q23 |
Hs.463506 |
27 |
RNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane membrane integral to membrane |
|
230082_at |
LOC100133660 |
hypothetical LOC100133660 |
3 |
|
AW137053 |
100133660 |
|
|
|
|
|
209858_x_at |
0.268 |
7.479 |
2.275 |
3.779e-02 |
0.564 |
-3.673 |
MPPE1 |
metallophosphoesterase 1 |
18 |
-11873471 |
BC002877 |
65258 |
18p11.21 |
Hs.712666 |
8 |
membrane integral to membrane hydrolase activity metal ion binding |
|
242900_at |
ALG10B |
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast) |
12 |
36996823 |
BF244214 |
144245 |
12q12 |
Hs.259305 |
5 |
plasma membrane integral to membrane transferase activity, transferring hexosyl groups |
N-Glycan biosynthesis Metabolic pathways |
211282_x_at |
TNFRSF25 |
tumor necrosis factor receptor superfamily, member 25 |
1 |
-6446757, -6443800 |
U94506 |
8718 |
1p36.2 |
Hs.462529 |
30 |
receptor activity tumor necrosis factor receptor activity protein binding extracellular region cytosol plasma membrane integral to plasma membrane cell surface receptor linked signal transduction induction of apoptosis by extracellular signals regulation of apoptosis |
Cytokine-cytokine receptor interaction |
202244_at |
PSMB4 |
proteasome (prosome, macropain) subunit, beta type, 4 |
1 |
149638664 |
NM_002796 |
5692 |
1q21 |
Hs.89545 |
46 |
threonine-type endopeptidase activity nucleus cytoplasm centrosome cytosol proteasome core complex cytoskeleton peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
218820_at |
C14orf132 |
chromosome 14 open reading frame 132 |
14 |
95575414 |
NM_020215 |
56967 |
14q32.2 |
Hs.6434 |
6 |
membrane integral to membrane |
|
212977_at |
CXCR7 |
chemokine (C-X-C motif) receptor 7 |
2 |
237143118 |
AI817041 |
57007 |
2q37.3 |
Hs.471751 |
21 |
receptor activity G-protein coupled receptor activity protein binding plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane interspecies interaction between organisms |
|
1562689_at |
-0.255 |
4.549 |
-2.448 |
2.695e-02 |
0.525 |
-3.392 |
LOC151484 |
hypothetical protein LOC151484 |
2 |
|
BC043555 |
151484 |
2q37.1 |
Hs.559309 |
1 |
|
|
213898_at |
-0.312 |
4.066 |
-2.879 |
1.134e-02 |
0.426 |
-2.663 |
RBM9 |
RNA binding motif protein 9 |
22 |
-34464728, -34464728 |
AW149379 |
23543 |
22q13.1 |
Hs.282998 |
18 |
nucleotide binding transcription corepressor activity RNA binding nucleus cytoplasm mRNA processing transcription factor binding RNA splicing RNA metabolic process negative regulation of transcription estrogen receptor signaling pathway regulation of cell proliferation |
|
235754_at |
HFE |
hemochromatosis |
6 |
26195487 |
AA088873 |
3077 |
6p21.3 |
Hs.233325 |
592 |
antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome |
|
1554541_a_at |
-0.388 |
4.981 |
-3.730 |
1.968e-03 |
0.273 |
-1.174 |
GPRIN2 |
G protein regulated inducer of neurite outgrowth 2 |
10 |
46413551 |
BC011672 |
9721 |
10q11.22 |
Hs.523375 |
7 |
|
|
215035_at |
IGLV6-57 |
immunoglobulin lambda variable 6-57 |
22 |
|
AI952772 |
28778 |
22q11.2 |
Hs.535668 |
6 |
|
|
233093_s_at |
BIRC6 |
baculoviral IAP repeat-containing 6 |
2 |
32435599 |
AK023788 |
57448 |
2p22-p21 |
Hs.150107 |
14 |
ubiquitin-protein ligase activity cysteine-type endopeptidase inhibitor activity protein binding cellular_component intracellular membrane fraction apoptosis anti-apoptosis positive regulation of cell proliferation ligase activity modification-dependent protein catabolic process peptidase inhibitor activity post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
1556134_a_at |
1.511 |
7.294 |
5.367 |
7.471e-05 |
0.162 |
1.547 |
B3GNT5 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
3 |
184453725 |
BC013229 |
84002 |
3q28 |
Hs.718506 |
7 |
intracellular Golgi apparatus protein amino acid glycosylation multicellular organismal development central nervous system development galactosyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity lipopolysaccharide N-acetylglucosaminyltransferase activity glycolipid biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups |
Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
210153_s_at |
0.430 |
7.460 |
2.971 |
9.411e-03 |
0.401 |
-2.505 |
ME2 |
malic enzyme 2, NAD(+)-dependent, mitochondrial |
18 |
46659432 |
M55905 |
4200 |
18q21 6p25-p24 |
Hs.233119 |
24 |
malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction |
Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide |
229838_at |
0.388 |
5.327 |
2.579 |
2.080e-02 |
0.497 |
-3.175 |
NUCB2 |
nucleobindin 2 |
11 |
17254861 |
AI377271 |
4925 |
11p15.1-p14 |
Hs.654599 |
15 |
DNA binding calcium ion binding extracellular region extracellular space nucleus nuclear outer membrane cytoplasm endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus cytosol plasma membrane |
|
240509_s_at |
0.361 |
2.488 |
2.177 |
4.565e-02 |
0.581 |
-3.829 |
GREM2 |
gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) |
1 |
-238719495 |
BF064262 |
64388 |
1q43 |
Hs.98206 |
9 |
cytokine activity extracellular region extracellular region extracellular space BMP signaling pathway |
|
204725_s_at |
NCK1 |
NCK adaptor protein 1 |
3 |
138063762 |
NM_006153 |
4690 |
3q21 |
Hs.477693 |
110 |
receptor binding cytoplasm endoplasmic reticulum regulation of translation actin filament organization signal complex assembly cytoskeletal adaptor activity vesicle membrane cell migration protein domain specific binding lamellipodium assembly receptor signaling complex scaffold activity positive regulation of actin filament polymerization positive regulation of T cell proliferation T cell activation |
ErbB signaling pathway Axon guidance T cell receptor signaling pathway Pathogenic Escherichia coli infection - EHEC |
226050_at |
0.906 |
6.706 |
2.600 |
1.991e-02 |
0.491 |
-3.138 |
TMCO3 |
transmembrane and coiled-coil domains 3 |
13 |
113193308 |
AL576117 |
55002 |
13q34 |
Hs.317593 |
6 |
cation transport antiporter activity solute:hydrogen antiporter activity membrane integral to membrane |
|
228891_at |
SEMA4D |
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
9 |
-91181971, -91165525 |
N93399 |
10507 |
9q22.2 |
Hs.494406 |
29 |
receptor activity receptor binding anti-apoptosis immune response cell adhesion multicellular organismal development nervous system development membrane integral to membrane cell differentiation positive regulation of axonogenesis |
Axon guidance |
220782_x_at |
-0.228 |
5.473 |
-2.295 |
3.633e-02 |
0.558 |
-3.641 |
KLK12 |
kallikrein-related peptidase 12 |
19 |
-56224159 |
NM_019598 |
43849 |
19q13.3-q13.4 |
Hs.411572 |
13 |
serine-type endopeptidase activity extracellular region soluble fraction proteolysis peptidase activity |
|
1554020_at |
0.533 |
3.793 |
3.033 |
8.274e-03 |
0.387 |
-2.395 |
BICD1 |
bicaudal D homolog 1 (Drosophila) |
12 |
32151451 |
BC010091 |
636 |
12p11.2-p11.1 |
Hs.505202 |
17 |
structural constituent of cytoskeleton protein binding Golgi apparatus cytoskeleton RNA processing transport intracellular mRNA localization anatomical structure morphogenesis |
|
232054_at |
1.366 |
3.202 |
3.082 |
7.498e-03 |
0.376 |
-2.311 |
PCDH20 |
protocadherin 20 |
13 |
-60881819 |
AA040057 |
64881 |
13q21 |
Hs.391781 |
9 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane |
|
206435_at |
B4GALNT1 |
beta-1,4-N-acetyl-galactosaminyl transferase 1 |
12 |
-56305817 |
NM_001478 |
2583 |
12q13.3 |
Hs.591019 |
11 |
ganglioside biosynthetic process (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity membrane fraction Golgi apparatus carbohydrate metabolic process glycosphingolipid metabolic process spermatogenesis membrane integral to membrane transferase activity, transferring hexosyl groups lipid storage integral to Golgi membrane lipid glycosylation |
Glycosphingolipid biosynthesis - ganglio series Metabolic pathways |
203574_at |
NFIL3 |
nuclear factor, interleukin 3 regulated |
9 |
-93211147 |
NM_005384 |
4783 |
9q22 |
Hs.79334 |
13 |
transcription factor activity transcription corepressor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter immune response sequence-specific DNA binding protein dimerization activity rhythmic process |
|
203610_s_at |
0.609 |
4.839 |
2.915 |
1.054e-02 |
0.418 |
-2.601 |
TRIM38 |
tripartite motif-containing 38 |
6 |
26071049 |
AI363270 |
10475 |
6p21.3 |
Hs.584851 |
7 |
signal transducer activity protein binding cellular_component intracellular zinc ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding |
|
201936_s_at |
EIF4G3 |
eukaryotic translation initiation factor 4 gamma, 3 |
1 |
-21005560 |
NM_003760 |
8672 |
1p36.12 |
Hs.467084 |
19 |
RNA cap binding translation initiation factor activity protein binding regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms |
|
221766_s_at |
FAM46A |
family with sequence similarity 46, member A |
6 |
-82512165 |
AW246673 |
55603 |
6q14 |
Hs.10784 |
11 |
|
|
212556_at |
-0.777 |
7.542 |
-3.367 |
4.164e-03 |
0.324 |
-1.811 |
SCRIB |
scribbled homolog (Drosophila) |
8 |
-144945077 |
AI469403 |
23513 |
8q24.3 |
Hs.436329 |
37 |
protein binding cytoplasm membrane |
|
223321_s_at |
-0.270 |
6.496 |
-3.098 |
7.255e-03 |
0.375 |
-2.283 |
FGFRL1 |
fibroblast growth factor receptor-like 1 |
4 |
995609, 995759, 996251 |
AF312678 |
53834 |
4p16 |
Hs.193326 |
15 |
regulation of cell growth receptor activity fibroblast growth factor receptor activity protein binding plasma membrane negative regulation of cell proliferation integral to membrane |
|
210304_at |
-0.324 |
5.012 |
-3.205 |
5.812e-03 |
0.357 |
-2.095 |
PDE6B |
phosphodiesterase 6B, cGMP-specific, rod, beta |
4 |
609362, 636965 |
BC000249 |
5158 |
4p16.3 |
Hs.623810 Hs.654544 |
30 |
signal transduction visual perception phototransduction, visible light detection of light stimulus membrane hydrolase activity 3',5'-cyclic-GMP phosphodiesterase activity response to stimulus |
|
1553007_a_at |
ODZ1 |
odz, odd Oz/ten-m homolog 1(Drosophila) |
X |
-123337436 |
NM_014253 |
10178 |
Xq25 |
Hs.23796 Hs.537002 Hs.716649 |
13 |
extracellular region integral to plasma membrane immune response signal transduction nervous system development heparin binding negative regulation of cell proliferation membrane |
|
225651_at |
0.373 |
7.266 |
2.247 |
3.987e-02 |
0.568 |
-3.717 |
UBE2E2 |
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) |
3 |
23219787 |
BF431962 |
7325 |
3p24.2 |
Hs.475688 Hs.595802 |
14 |
nucleotide binding ubiquitin-protein ligase activity ATP binding ligase activity modification-dependent protein catabolic process ISG15-protein conjugation ISG15 ligase activity regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
206710_s_at |
1.155 |
4.228 |
3.131 |
6.771e-03 |
0.368 |
-2.225 |
EPB41L3 |
erythrocyte membrane protein band 4.1-like 3 |
18 |
-5382387 |
NM_012307 |
23136 |
18p11.32 |
Hs.213394 |
39 |
actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization |
Tight junction |
218145_at |
TRIB3 |
tribbles homolog 3 (Drosophila) |
20 |
309307 |
NM_021158 |
57761 |
20p13-p12.2 |
Hs.516826 |
36 |
transcription corepressor activity protein kinase activity protein kinase inhibitor activity protein binding protein binding ATP binding nucleus nucleolus protein amino acid phosphorylation negative regulation of protein kinase activity apoptosis response to stress protein kinase binding protein kinase binding regulation of MAP kinase activity regulation of transcription |
|
235300_x_at |
RCHY1 |
ring finger and CHY zinc finger domain containing 1 |
4 |
-76623370 |
AW236209 |
25898 |
4q21.1 |
Hs.48297 |
20 |
protein binding nucleus cytoplasm zinc ion binding metal ion binding |
p53 signaling pathway Ubiquitin mediated proteolysis |
222532_at |
SRPRB |
signal recognition particle receptor, B subunit |
3 |
135007366 |
BF983948 |
58477 |
3q22.1 |
Hs.12152 |
10 |
nucleotide binding receptor activity protein binding GTP binding endoplasmic reticulum membrane integral to membrane ribonucleoprotein complex |
|
202390_s_at |
HTT |
huntingtin |
4 |
3046205 |
NM_002111 |
3064 |
4p16.3 |
Hs.518450 |
252 |
urea cycle citrulline metabolic process transcription corepressor activity transporter activity calcium channel regulator activity protein binding soluble fraction nucleus cytoplasm Golgi apparatus protein import into nucleus ER to Golgi vesicle-mediated transport anti-apoptosis induction of apoptosis mitochondrion organization endoplasmic reticulum organization dopamine receptor signaling pathway spermatogenesis gastrulation brain development cell aging locomotory behavior microtubule binding axon cargo transport associative learning determination of adult lifespan visual learning pathogenesis embryonic development organ morphogenesis anterior/posterior pattern formation cytoplasmic membrane-bounded vesicle endosome transport inclusion body lactate biosynthetic process from pyruvate quinolinate biosynthetic process striatum development olfactory lobe development neural plate formation neurogenesis insulin secretion axon social behavior hormone metabolic process negative regulation of neuron apoptosis regulation of mitochondrial membrane permeability vesicle transport along microtubule regulation of synaptic plasticity paraxial mesoderm formation neuron development diazepam binding response to calcium ion regulation of mitochondrial membrane potential L-glutamate import iron ion homeostasis |
Huntington's disease |
209654_at |
KIAA0947 |
KIAA0947 |
5 |
5475806 |
BC004902 |
23379 |
5p15.32 |
Hs.449296 |
3 |
|
|
211778_s_at |
OVOL2 |
ovo-like 2 (Drosophila) |
20 |
-17952795 |
BC006148 |
58495 |
20pter-q11.23 |
Hs.661013 Hs.710157 |
5 |
neural crest cell migration neural fold formation DNA binding intracellular nucleus heart development zinc ion binding negative regulation of cell proliferation dorsal/ventral pattern formation regulation of transcription negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding embryonic gut morphogenesis |
|
1555399_a_at |
DUSP16 |
dual specificity phosphatase 16 |
12 |
-12520097 |
AY038927 |
80824 |
12p13 |
Hs.536535 |
12 |
inactivation of MAPK activity protein tyrosine phosphatase activity protein binding nucleus cytoplasm protein amino acid dephosphorylation hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAPK export from nucleus MAPK phosphatase export from nucleus, leptomycin B sensitive |
MAPK signaling pathway |
232652_x_at |
0.356 |
7.547 |
2.570 |
2.116e-02 |
0.497 |
-3.189 |
SCAND1 |
SCAN domain containing 1 |
20 |
-34004959 |
AF207829 |
51282 |
20q11.1-q11.23 |
Hs.584909 |
14 |
transcription factor activity transcription coactivator activity nucleus regulation of transcription, DNA-dependent identical protein binding |
|
226856_at |
MUSTN1 |
musculoskeletal, embryonic nuclear protein 1 |
3 |
-52842176 |
BF793701 |
389125 |
3p21.1 |
Hs.556077 |
1 |
nucleus |
|
1557918_s_at |
-0.248 |
5.117 |
-2.348 |
3.279e-02 |
0.550 |
-3.556 |
SLC16A1 |
solute carrier family 16, member 1 (monocarboxylic acid transporter 1) |
1 |
-113255992 |
AU131482 |
6566 |
1p12 |
Hs.75231 |
43 |
protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane |
|
232922_s_at |
SLC17A9 |
solute carrier family 17, member 9 |
20 |
61054443 |
BG419965 |
63910 |
20q13.33 |
Hs.512686 |
7 |
transporter activity transport exocytosis membrane integral to membrane |
|
206605_at |
P11 |
26 serine protease |
12 |
-46389794 |
NM_006025 |
8909 |
12q13.1 |
Hs.997 |
7 |
scavenger receptor activity extracellular region extracellular space cytoplasm cytoplasm plasma membrane proteolysis immune response female pregnancy growth factor activity peptidase activity serine-type peptidase activity polysaccharide binding |
|
232055_at |
SFXN1 |
sideroflexin 1 |
5 |
174838119 |
AA960991 |
94081 |
|
Hs.369440 |
18 |
iron ion binding protein binding mitochondrion mitochondrial inner membrane cation transport iron ion transport cation transmembrane transporter activity membrane integral to membrane erythrocyte differentiation |
|
220349_s_at |
0.436 |
7.377 |
3.024 |
8.437e-03 |
0.388 |
-2.412 |
ENGASE |
endo-beta-N-acetylglucosaminidase |
17 |
74582613 |
NM_022759 |
64772 |
17q25.3 |
Hs.29288 |
5 |
intracellular cytoplasm cytosol metabolic process hydrolase activity, acting on glycosyl bonds mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity |
Other glycan degradation |
227002_at |
-0.385 |
8.112 |
-2.509 |
2.391e-02 |
0.509 |
-3.292 |
FAM78A |
family with sequence similarity 78, member A |
9 |
-133123285 |
BF515132 |
286336 |
9q34 |
Hs.143878 Hs.704076 |
5 |
|
|
208718_at |
DDX17 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 |
22 |
-37209388, -37209388 |
Z97056 |
10521 |
22q13.1 |
Hs.528305 Hs.665429 Hs.719084 |
28 |
nucleotide binding RNA binding RNA helicase activity ATP binding nucleus RNA processing ATP-dependent helicase activity RNA-dependent ATPase activity hydrolase activity |
|
1563263_at |
PLCG2 |
phospholipase C, gamma 2 (phosphatidylinositol-specific) |
16 |
80370430 |
BC040927 |
5336 |
16q24.1 |
Hs.413111 |
63 |
follicular B cell differentiation phosphoinositide phospholipase C activity signal transducer activity calcium ion binding protein binding plasma membrane intracellular signaling cascade phospholipid catabolic process regulation of gene expression lipid catabolic process hydrolase activity activation of store-operated calcium channel activity response to lipopolysaccharide inositol trisphosphate biosynthetic process negative regulation of programmed cell death T cell receptor signaling pathway |
Inositol phosphate metabolism Metabolic pathways ErbB signaling pathway Calcium signaling pathway Phosphatidylinositol signaling system VEGF signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Glioma Non-small cell lung cancer |
208366_at |
-0.288 |
3.531 |
-2.256 |
3.919e-02 |
0.567 |
-3.703 |
PCDH11X |
protocadherin 11 X-linked |
X |
90920959, 90976314, 90976314 |
NM_014522 |
27328 |
Xq21.3 |
Hs.655673 |
16 |
calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion |
|
219408_at |
0.318 |
6.260 |
2.363 |
3.183e-02 |
0.544 |
-3.531 |
PRMT7 |
protein arginine methyltransferase 7 |
16 |
66902445 |
NM_019023 |
54496 |
16q22.1 |
Hs.712584 |
9 |
spliceosomal snRNP biogenesis nucleus cytoplasm cytosol genetic imprinting S-adenosylmethionine-dependent methyltransferase activity [myelin basic protein]-arginine N-methyltransferase activity chromatin modification transferase activity peptidyl-arginine methylation cell differentiation histone arginine methylation protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N symmetric methyltransferase activity protein-arginine omega-N symmetric methyltransferase activity histone binding ribonucleoprotein binding DNA methylation during gametogenesis regulation of protein binding histone methyltransferase activity (H4-R3 specific) regulation of transcription |
|
213353_at |
ABCA5 |
ATP-binding cassette, sub-family A (ABC1), member 5 |
17 |
-64752170, -64752170 |
BF693921 |
23461 |
17q24.3 |
Hs.421474 |
11 |
nucleotide binding ATP binding lysosome endosome Golgi apparatus transport membrane integral to membrane ATPase activity |
ABC transporters |
203192_at |
ABCB6 |
ATP-binding cassette, sub-family B (MDR/TAP), member 6 |
2 |
-219782737 |
NM_005689 |
10058 |
2q36 |
Hs.107911 |
15 |
nucleotide binding ATP binding mitochondrion mitochondrial envelope mitochondrial outer membrane transport cellular iron ion homeostasis membrane integral to membrane ATPase activity ATPase activity, coupled to transmembrane movement of substances ATP-binding cassette (ABC) transporter complex |
ABC transporters |
226464_at |
C3orf58 |
chromosome 3 open reading frame 58 |
3 |
145173329, 145174856 |
BE348597 |
205428 |
3q24 |
Hs.288954 |
5 |
extracellular region |
|
206561_s_at |
AKR1B10 |
aldo-keto reductase family 1, member B10 (aldose reductase) |
7 |
133862883 |
NM_020299 |
57016 |
7q33 |
Hs.116724 |
30 |
aldo-keto reductase activity protein binding cellular_component cytoplasm cellular aldehyde metabolic process digestion steroid metabolic process oxidoreductase activity oxidation reduction |
Fructose and mannose metabolism Bisphenol A degradation Linoleic acid metabolism Tetrachloroethene degradation Butanoate metabolism Metabolic pathways |
232599_at |
EXOC6 |
exocyst complex component 6 |
10 |
94584449, 94598204 |
AF220217 |
54536 |
10q23.33 |
Hs.655657 |
8 |
exocyst vesicle docking during exocytosis protein transport |
|
224697_at |
0.285 |
5.988 |
2.479 |
2.537e-02 |
0.515 |
-3.342 |
DCAF5 |
DDB1 and CUL4 associated factor 5 |
14 |
-68587390 |
AI568478 |
8816 |
14q23-q24.1 |
Hs.509780 |
6 |
|
|
201556_s_at |
-0.510 |
5.130 |
-4.092 |
9.360e-04 |
0.222 |
-0.544 |
VAMP2 |
vesicle-associated membrane protein 2 (synaptobrevin 2) |
17 |
-8003189 |
BC002737 |
6844 |
17p13.1 |
Hs.25348 |
66 |
protein binding integral to plasma membrane membrane vesicle-mediated transport synaptosome cell junction cytoplasmic vesicle synapse |
SNARE interactions in vesicular transport |
221597_s_at |
0.381 |
6.834 |
2.579 |
2.079e-02 |
0.497 |
-3.175 |
TMEM208 |
transmembrane protein 208 |
16 |
65818516 |
BC003080 |
29100 |
16q22.1 |
Hs.433203 |
2 |
membrane integral to membrane |
|
215268_at |
KIAA0754 |
KIAA0754 |
1 |
39647762 |
AW663712 |
643314 |
1p34.3 |
Hs.658760 |
1 |
|
|
202595_s_at |
0.368 |
6.046 |
2.908 |
1.070e-02 |
0.420 |
-2.613 |
LEPROTL1 |
leptin receptor overlapping transcript-like 1 |
8 |
30072463, 30072463 |
AF161461 |
23484 |
8p21.2-p21.1 |
Hs.146585 |
8 |
membrane integral to membrane |
|
218350_s_at |
-0.571 |
6.782 |
-3.460 |
3.434e-03 |
0.308 |
-1.647 |
GMNN |
geminin, DNA replication inhibitor |
6 |
24883142 |
NM_015895 |
51053 |
6p22.3 |
Hs.234896 |
40 |
protein binding nucleoplasm negative regulation of DNA replication negative regulation of cell cycle |
|
205395_s_at |
MRE11A |
MRE11 meiotic recombination 11 homolog A (S. cerevisiae) |
11 |
-93790114 |
NM_005590 |
4361 |
11q21 |
Hs.192649 |
107 |
single-stranded DNA specific endodeoxyribonuclease activity regulation of mitotic recombination DNA binding double-stranded DNA binding nucleus nucleoplasm nucleolus double-strand break repair via nonhomologous end joining response to DNA damage stimulus telomere maintenance via telomerase meiosis reciprocal meiotic recombination protein C-terminus binding 3'-5' exonuclease activity hydrolase activity manganese ion binding |
Homologous recombination Non-homologous end-joining |
240342_at |
TRIM61 |
tripartite motif-containing 61 |
4 |
-166095049 |
BF508746 |
391712 |
4q32.3 |
Hs.654633 |
4 |
protein binding intracellular zinc ion binding metal ion binding |
|
233632_s_at |
XRN1 |
5'-3' exoribonuclease 1 |
3 |
-143508138 |
AL117516 |
54464 |
3q23 |
Hs.435103 |
12 |
DNA binding RNA binding protein binding intracellular cytoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 5'-3' exonuclease activity hydrolase activity |
RNA degradation |
206235_at |
0.509 |
4.536 |
3.181 |
6.110e-03 |
0.360 |
-2.137 |
LIG4 |
ligase IV, DNA, ATP-dependent |
13 |
-107657792, -107657792, -107657792 |
NM_002312 |
3981 |
13q33-q34 |
Hs.166091 |
82 |
single strand break repair nucleotide binding magnesium ion binding condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding DNA ligase (ATP) activity ATP binding intracellular nucleus cytoplasm plasma membrane focal adhesion DNA-dependent protein kinase-DNA ligase 4 complex DNA replication nucleotide-excision repair, DNA gap filling double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus cell cycle central nervous system development protein C-terminus binding cell proliferation response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination T cell receptor V(D)J recombination somatic stem cell maintenance negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA recombination DNA ligation during DNA repair DNA ligation during DNA repair chromosome organization cell division |
Non-homologous end-joining |
218067_s_at |
ARGLU1 |
arginine and glutamate rich 1 |
13 |
-105993662 |
NM_018011 |
55082 |
13q33.3 |
Hs.508644 Hs.701016 |
3 |
|
|
1570025_at |
-1.128 |
5.639 |
-6.931 |
4.451e-06 |
0.039 |
3.742 |
TACC2 |
transforming, acidic coiled-coil containing protein 2 |
10 |
123738678, 123913094 |
BC010219 |
10579 |
10q26 |
Hs.501252 Hs.713875 |
18 |
protein binding nucleus cytoplasm centrosome nuclear hormone receptor binding |
|
200597_at |
EIF3A |
eukaryotic translation initiation factor 3, subunit A |
10 |
-120784530 |
AI123320 |
8661 |
10q26 |
Hs.523299 |
38 |
formation of translation initiation complex translation initiation factor activity translation initiation factor activity structural molecule activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex |
|
215649_s_at |
MVK |
mevalonate kinase |
12 |
108495882 |
AF217536 |
4598 |
12q24 |
Hs.130607 |
42 |
nucleotide binding mevalonate kinase activity ATP binding cytoplasm peroxisome cholesterol biosynthetic process metabolic process isoprenoid biosynthetic process phosphorylation transferase activity identical protein binding |
Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
208315_x_at |
TRAF3 |
TNF receptor-associated factor 3 |
14 |
102313568 |
NM_003300 |
7187 |
14q32.32 |
Hs.510528 |
99 |
signal transducer activity protein binding cytoplasm induction of apoptosis signal transduction zinc ion binding regulation of apoptosis metal ion binding |
Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Pathways in cancer Small cell lung cancer |
201428_at |
CLDN4 |
claudin 4 |
7 |
72883128 |
NM_001305 |
1364 |
7q11.23 |
Hs.647036 Hs.699253 Hs.718794 |
55 |
transmembrane receptor activity structural molecule activity plasma membrane integral to plasma membrane tight junction pathogenesis calcium-independent cell-cell adhesion cell junction identical protein binding |
Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration |
206020_at |
SOCS6 |
suppressor of cytokine signaling 6 |
18 |
66107116 |
NM_016387 |
9306 |
18q22.2 |
Hs.44439 |
13 |
protein binding cytoplasm defense response intracellular signaling cascade JAK-STAT cascade negative regulation of signal transduction modification-dependent protein catabolic process regulation of growth |
|
211359_s_at |
OPRM1 |
opioid receptor, mu 1 |
6 |
154373328, 154402135, 154402135, 154402135, 154402135, 154402135, 154402135, 154402135, 154402238, 154449334 |
U12569 |
4988 |
6q24-q25 |
Hs.2353 |
192 |
receptor activity G-protein coupled receptor activity mu-opioid receptor activity endoplasmic reticulum Golgi apparatus plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger sensory perception behavior negative regulation of cell proliferation |
Neuroactive ligand-receptor interaction |
1555736_a_at |
0.794 |
6.524 |
2.293 |
3.650e-02 |
0.559 |
-3.644 |
AGTRAP |
angiotensin II receptor-associated protein |
1 |
11718728 |
AF165187 |
57085 |
1p36.22 |
Hs.464438 |
14 |
protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane cytoplasmic vesicle |
|
217227_x_at |
IGL@ |
immunoglobulin lambda locus |
22 |
|
X93006 |
3535 |
22q11.1-q11.2 |
Hs.449585 Hs.561078 |
20 |
|
|
204376_at |
VPRBP |
Vpr (HIV-1) binding protein |
3 |
-51408337 |
NM_014703 |
9730 |
3p21.2 |
Hs.716623 |
14 |
binding cytoplasm modification-dependent protein catabolic process interspecies interaction between organisms |
|
214797_s_at |
PCTK3 |
PCTAIRE protein kinase 3 |
1 |
203740349 |
BC000281 |
5129 |
1q31-q32 |
Hs.445402 |
13 |
nucleotide binding cyclin-dependent protein kinase activity signal transducer activity protein binding ATP binding cellular_component protein amino acid phosphorylation signal transduction transferase activity |
|
225639_at |
SKAP2 |
src kinase associated phosphoprotein 2 |
7 |
-26673212 |
N21390 |
8935 |
7p21-p15 |
Hs.200770 Hs.644804 |
19 |
SH3/SH2 adaptor activity cytoplasm plasma membrane protein complex assembly signal transduction negative regulation of cell proliferation B cell activation |
|
219863_at |
-0.313 |
4.663 |
-2.275 |
3.776e-02 |
0.564 |
-3.673 |
HERC5 |
hect domain and RLD 5 |
4 |
89597290 |
NM_016323 |
51191 |
4q22.1 |
Hs.26663 |
10 |
regulation of cyclin-dependent protein kinase activity intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process perinuclear region of cytoplasm |
|
236064_at |
SLC25A35 |
solute carrier family 25, member 35 |
17 |
-8131806 |
AW966184 |
399512 |
17p13.1 |
Hs.118918 |
3 |
binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
212429_s_at |
GTF3C2 |
general transcription factor IIIC, polypeptide 2, beta 110kDa |
2 |
-27402224 |
AW194657 |
2976 |
2p23.3 |
Hs.75782 |
18 |
transcription factor TFIIIC complex DNA binding RNA polymerase III transcription factor activity protein binding nucleus mitochondrion peroxisome transcription, DNA-dependent oxygen and reactive oxygen species metabolic process 5S class rRNA transcription tRNA transcription from RNA polymerase III promoter |
|
232810_at |
AIG1 |
androgen-induced 1 |
6 |
143423715 |
AK001347 |
51390 |
6q24.2 |
Hs.567501 |
8 |
membrane integral to membrane |
|
203724_s_at |
RUFY3 |
RUN and FYVE domain containing 3 |
4 |
71789517, 71806559, 71806559 |
NM_014961 |
22902 |
4q13.3 |
Hs.713172 |
8 |
multicellular organismal development nervous system development cell differentiation filopodium growth cone negative regulation of axonogenesis |
|
227123_at |
-0.266 |
3.818 |
-2.564 |
2.140e-02 |
0.497 |
-3.199 |
RAB3B |
RAB3B, member RAS oncogene family |
1 |
-52157422 |
AU156710 |
5865 |
1p32-p31 |
Hs.123072 |
15 |
nucleotide binding GTPase activity protein binding GTP binding plasma membrane small GTPase mediated signal transduction synaptic vesicle protein transport regulation of exocytosis peptidyl-cysteine methylation |
Tight junction |
203785_s_at |
0.568 |
6.058 |
3.735 |
1.948e-03 |
0.273 |
-1.165 |
DDX28 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
16 |
-66612674 |
NM_018380 |
55794 |
16q22.1 |
Hs.458313 |
9 |
nucleotide binding RNA binding helicase activity ATP binding nucleus mitochondrion ATP-dependent helicase activity hydrolase activity mitochondrial nucleoid |
|
212186_at |
0.481 |
6.822 |
3.271 |
5.072e-03 |
0.345 |
-1.979 |
ACACA |
acetyl-Coenzyme A carboxylase alpha |
17 |
-32516039, -32516039, -32516039 |
BE855983 |
31 |
17q21 |
Hs.160556 |
35 |
nucleotide binding acetyl-CoA carboxylase activity biotin carboxylase activity protein binding ATP binding cytoplasm fatty acid biosynthetic process metabolic process biotin binding ligase activity manganese ion binding metal ion binding |
Fatty acid biosynthesis Pyruvate metabolism Propanoate metabolism Metabolic pathways Insulin signaling pathway |
1553960_at |
0.696 |
7.328 |
3.290 |
4.881e-03 |
0.341 |
-1.946 |
SNX21 |
sorting nexin family member 21 |
20 |
43895876 |
CA447177 |
90203 |
20q13.12 |
Hs.472854 |
8 |
protein binding cell communication protein transport phosphoinositide binding |
|
230363_s_at |
INPP5F |
inositol polyphosphate-5-phosphatase F |
10 |
121475598, 121475598, 121568775 |
BE858808 |
22876 |
10q26.11 |
Hs.369755 |
7 |
hydrolase activity |
|
227322_s_at |
0.349 |
8.389 |
2.838 |
1.234e-02 |
0.427 |
-2.734 |
BCCIP |
BRCA2 and CDKN1A interacting protein |
10 |
127502093, 127502093, 127502093 |
BE464077 |
56647 |
10q26.1 |
Hs.370292 Hs.715543 |
31 |
regulation of cyclin-dependent protein kinase activity protein binding nucleus DNA repair response to DNA damage stimulus cell cycle |
|
208674_x_at |
DDOST |
dolichyl-diphosphooligosaccharide-protein glycosyltransferase |
1 |
-20850846 |
BC002594 |
1650 |
1p36.1 |
Hs.523145 |
12 |
dolichyl-diphosphooligosaccharide-protein glycotransferase activity protein binding endoplasmic reticulum microsome protein amino acid terminal N-glycosylation oligosaccharyltransferase complex membrane integral to membrane transferase activity protein amino acid N-linked glycosylation via asparagine response to cytokine stimulus T cell activation |
N-Glycan biosynthesis Metabolic pathways |
212845_at |
SAMD4A |
sterile alpha motif domain containing 4A |
14 |
54104386, 54291255 |
AB028976 |
23034 |
14q22.2 |
Hs.98259 |
4 |
cytoplasm synaptosome translation repressor activity dendrite positive regulation of translation |
|
212010_s_at |
CDV3 |
CDV3 homolog (mouse) |
3 |
134775123, 134775990 |
AK025647 |
55573 |
3q22.1 |
Hs.518265 |
11 |
molecular_function cellular_component cytoplasm cell proliferation |
|
242722_at |
0.471 |
6.194 |
2.836 |
1.239e-02 |
0.427 |
-2.737 |
LMO7 |
LIM domain 7 |
13 |
75092570, 75232797 |
AA100793 |
4008 |
13q22.2 |
Hs.207631 |
18 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm zinc ion binding protein ubiquitination metal ion binding |
Adherens junction |
215690_x_at |
0.263 |
8.023 |
2.201 |
4.358e-02 |
0.578 |
-3.791 |
GPAA1 |
glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) |
8 |
145209511 |
AL157437 |
8733 |
8q24.3 |
Hs.627962 |
16 |
GPI-anchor transamidase activity protein binding endoplasmic reticulum protein complex assembly protein retention in ER lumen tubulin binding membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein attachment of GPI anchor to protein GPI anchor binding GPI-anchor transamidase complex |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways |
1568978_s_at |
C11orf21 |
chromosome 11 open reading frame 21 |
11 |
-2274082 |
BM547346 |
29125 |
11p15.5 |
Hs.559181 |
2 |
cytoplasm |
|
1563082_at |
LOC285045 |
hypothetical LOC285045 |
2 |
32904013, 32961269, 32961371 |
BC040883 |
285045 |
2p22.3 |
Hs.434660 |
2 |
|
|
226350_at |
CHML |
choroideremia-like (Rab escort protein 2) |
1 |
-239858789 |
AU155565 |
1122 |
1q42-qter |
Hs.654545 |
17 |
Rab geranylgeranyltransferase activity GTPase activator activity Rab-protein geranylgeranyltransferase complex intracellular protein transport visual perception regulation of GTPase activity |
|
233523_at |
-0.349 |
4.436 |
-3.027 |
8.388e-03 |
0.388 |
-2.407 |
C20orf186 |
chromosome 20 open reading frame 186 |
20 |
31132978 |
AL121756 |
149954 |
20q11.21 |
Hs.38961 |
4 |
extracellular region cytoplasm lipid binding |
|
225921_at |
NIN |
ninein (GSK3B interacting protein) |
14 |
-50263700, -50262296, -50262296, -50256230 |
AL359571 |
51199 |
14q22.1 |
Hs.310429 |
23 |
nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization |
|
205116_at |
0.726 |
6.684 |
4.849 |
2.044e-04 |
0.172 |
0.726 |
LAMA2 |
laminin, alpha 2 |
6 |
129245978 |
NM_000426 |
3908 |
6q22-q23 |
Hs.200841 |
40 |
receptor binding structural molecule activity extracellular region basal lamina laminin-1 complex muscle organ development regulation of cell adhesion regulation of cell migration positive regulation of synaptic transmission, cholinergic sarcolemma regulation of embryonic development |
Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
206717_at |
MYH8 |
myosin, heavy chain 8, skeletal muscle, perinatal |
17 |
-10234366 |
NM_002472 |
4626 |
17p13.1 |
Hs.700484 |
10 |
nucleotide binding motor activity actin binding calmodulin binding ATP binding cytoplasm striated muscle thick filament striated muscle contraction structural constituent of muscle myosin complex myofibril |
Tight junction |
1555865_at |
0.622 |
5.315 |
2.978 |
9.264e-03 |
0.400 |
-2.491 |
LOC255512 |
hypothetical protein LOC255512 |
11 |
|
R67325 |
255512 |
11p15.5 |
Hs.588291 |
1 |
|
|
216083_s_at |
-0.315 |
5.442 |
-2.760 |
1.444e-02 |
0.447 |
-2.867 |
NEU3 |
sialidase 3 (membrane sialidase) |
11 |
74377597 |
AK022450 |
10825 |
11q13.5 |
Hs.191074 |
25 |
exo-alpha-sialidase activity plasma membrane integral to plasma membrane carbohydrate metabolic process ganglioside catabolic process metabolic process hydrolase activity, acting on glycosyl bonds |
Other glycan degradation Sphingolipid metabolism |
1552611_a_at |
JAK1 |
Janus kinase 1 |
1 |
-65071493 |
AL555086 |
3716 |
1p32.3-p31.3 |
Hs.207538 |
118 |
nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity growth hormone receptor binding protein binding ATP binding nucleus cytoplasm cytoskeleton enzyme linked receptor protein signaling pathway protein kinase cascade membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway response to antibiotic |
Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer |
241343_at |
RNASEH1 |
ribonuclease H1 |
2 |
-3570565 |
BF127479 |
246243 |
2p25 |
Hs.568006 |
20 |
magnesium ion binding RNA binding endonuclease activity ribonuclease H activity ribonuclease activity cytoplasm mitochondrion RNA catabolic process hydrolase activity |
DNA replication |
217810_x_at |
LARS |
leucyl-tRNA synthetase |
5 |
-145472781 |
NM_020117 |
51520 |
5q32 |
Hs.432674 |
20 |
nucleotide binding leucine-tRNA ligase activity ATP binding cytoplasm leucyl-tRNA aminoacylation ligase activity |
Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis |
227285_at |
C1orf51 |
chromosome 1 open reading frame 51 |
1 |
148521852 |
AW080835 |
148523 |
1q21.2 |
Hs.54680 |
4 |
|
|
223636_at |
ZMYND12 |
zinc finger, MYND-type containing 12 |
1 |
-42668589 |
AL136858 |
84217 |
1p34.2 |
Hs.294009 |
5 |
binding intracellular zinc ion binding metal ion binding |
|
215918_s_at |
SPTBN1 |
spectrin, beta, non-erythrocytic 1 |
2 |
54536957, 54639034 |
AA131826 |
6711 |
2p21 |
Hs.503178 Hs.705692 |
46 |
actin binding structural constituent of cytoskeleton calmodulin binding nucleus nucleolus cytoplasm plasma membrane common-partner SMAD protein phosphorylation SMAD protein nuclear translocation spectrin cortical cytoskeleton M band actin filament capping |
|
222142_at |
0.457 |
3.687 |
2.435 |
2.765e-02 |
0.526 |
-3.413 |
CYLD |
cylindromatosis (turban tumor syndrome) |
16 |
49333461, 49333529 |
AK024212 |
1540 |
16q12.1 |
Hs.578973 |
54 |
structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm |
RIG-I-like receptor signaling pathway |
219625_s_at |
COL4A3BP |
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
5 |
-74702683, -74702683 |
NM_005713 |
10087 |
5q13.3 |
Hs.270437 |
26 |
protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response |
|
207711_at |
C20orf117 |
chromosome 20 open reading frame 117 |
20 |
-34839258 |
NM_015377 |
140710 |
20q11.23 |
Hs.460807 Hs.719179 |
8 |
|
|
227707_at |
-0.407 |
5.074 |
-2.794 |
1.349e-02 |
0.437 |
-2.810 |
MYLIP |
myosin regulatory light chain interacting protein |
6 |
16237295 |
AW027183 |
29116 |
6p23-p22.3 |
Hs.484738 |
10 |
ubiquitin-protein ligase activity intracellular cytoplasm cytoskeleton cell motion nervous system development cytoskeletal protein binding zinc ion binding protein ubiquitination ligase activity extrinsic to membrane modification-dependent protein catabolic process metal ion binding |
|
204022_at |
WWP2 |
WW domain containing E3 ubiquitin protein ligase 2 |
16 |
68353774, 68353774, 68516401 |
AI668780 |
11060 |
16q22.1 |
Hs.408458 |
20 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding intracellular protein modification process negative regulation of gene expression protein ubiquitination ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process negative regulation of transporter activity interspecies interaction between organisms entry of virus into host cell negative regulation of protein transport |
Ubiquitin mediated proteolysis |
206421_s_at |
-0.262 |
3.939 |
-3.042 |
8.125e-03 |
0.387 |
-2.380 |
SERPINB7 |
serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
18 |
59571256, 59593591 |
NM_003784 |
8710 |
18q21.33 |
Hs.138202 |
17 |
serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity |
|
202966_at |
0.562 |
3.606 |
3.491 |
3.225e-03 |
0.306 |
-1.594 |
CAPN6 |
calpain 6 |
X |
-110374986 |
NM_014289 |
827 |
Xq23 |
Hs.496593 |
8 |
calcium-dependent cysteine-type endopeptidase activity intracellular proteolysis |
|
208233_at |
PDPN |
podoplanin |
1 |
13782838, 13784553 |
NM_013317 |
10630 |
1p36.21 |
Hs.468675 |
48 |
cell morphogenesis ruffle lymphangiogenesis plasma membrane integral to plasma membrane prostaglandin metabolic process water transport cell cycle signal transduction multicellular organismal development cell proliferation regulation of cell shape folic acid transporter activity amino acid transmembrane transporter activity water channel activity folic acid transport cell-cell adhesion lamellipodium filopodium positive regulation of cell migration tube morphogenesis lung alveolus development |
|
207771_at |
-0.286 |
5.648 |
-3.287 |
4.908e-03 |
0.341 |
-1.951 |
SLC5A2 |
solute carrier family 5 (sodium/glucose cotransporter), member 2 |
16 |
31401939 |
NM_003041 |
6524 |
16p12-p11 |
Hs.709195 |
9 |
transporter activity low-affinity glucose:sodium symporter activity carbohydrate metabolic process ion transport sodium ion transport carbohydrate transport symporter activity glucose transport membrane integral to membrane sodium ion binding brush border membrane |
|
201648_at |
0.362 |
9.116 |
2.295 |
3.637e-02 |
0.559 |
-3.642 |
JAK1 |
Janus kinase 1 |
1 |
-65071493 |
AL039831 |
3716 |
1p32.3-p31.3 |
Hs.207538 |
118 |
nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity growth hormone receptor binding protein binding ATP binding nucleus cytoplasm cytoskeleton enzyme linked receptor protein signaling pathway protein kinase cascade membrane transferase activity peptidyl-tyrosine phosphorylation cytokine-mediated signaling pathway response to antibiotic |
Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer |
218371_s_at |
PSPC1 |
paraspeckle component 1 |
13 |
-19175008, -19146895 |
NM_018282 |
55269 |
13q12.11 |
Hs.213198 |
9 |
nucleotide binding RNA binding protein binding nucleus nucleolus cytoplasm nuclear matrix regulation of transcription |
|
213369_at |
PCDH21 |
protocadherin 21 |
10 |
85944496 |
AI825832 |
92211 |
10q22.1-q22.3 |
Hs.137556 |
3 |
receptor activity calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion photoreceptor cell maintenance response to stimulus |
|
226578_s_at |
-0.263 |
5.770 |
-2.175 |
4.583e-02 |
0.581 |
-3.832 |
DUSP1 |
dual specificity phosphatase 1 |
5 |
-172127706 |
AW024420 |
1843 |
5q34 |
Hs.171695 |
73 |
non-membrane spanning protein tyrosine phosphatase activity protein binding protein amino acid dephosphorylation response to oxidative stress cell cycle intracellular signaling cascade hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity |
MAPK signaling pathway |
226567_at |
USP14 |
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
18 |
148482 |
BG283995 |
9097 |
18p11.32 |
Hs.464416 Hs.707058 |
15 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity |
|
206219_s_at |
-0.283 |
3.736 |
-2.711 |
1.596e-02 |
0.459 |
-2.952 |
VAV1 |
vav 1 guanine nucleotide exchange factor |
19 |
6723721 |
NM_005428 |
7409 |
19p13.2 |
Hs.116237 |
134 |
transcription factor activity guanyl-nucleotide exchange factor activity protein binding intracellular phagocytosis immune response integrin-mediated signaling pathway intracellular signaling cascade zinc ion binding diacylglycerol binding Rac guanyl-nucleotide exchange factor activity regulation of Rho protein signal transduction T cell activation regulation of GTPase activity positive regulation of cell adhesion metal ion binding |
Chemokine signaling pathway Focal adhesion Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Regulation of actin cytoskeleton |
218584_at |
0.351 |
6.253 |
2.961 |
9.592e-03 |
0.405 |
-2.521 |
TCTN1 |
tectonic family member 1 |
12 |
109536262 |
NM_024549 |
79600 |
12q24.11 |
Hs.211511 Hs.694390 |
5 |
extracellular region multicellular organismal development |
|
207180_s_at |
0.319 |
7.429 |
2.725 |
1.549e-02 |
0.458 |
-2.927 |
HTATIP2 |
HIV-1 Tat interactive protein 2, 30kDa |
11 |
20341806, 20341822, 20341864, 20341978, 20342262 |
NM_006410 |
10553 |
11p15.1 |
Hs.90753 |
31 |
RNA polymerase II transcription factor activity transcription coactivator activity protein binding nucleus nuclear envelope cytoplasm regulation of transcription from RNA polymerase II promoter anti-apoptosis induction of apoptosis multicellular organismal development oxidoreductase activity cell differentiation regulation of apoptosis interspecies interaction between organisms regulation of angiogenesis nuclear import oxidation reduction |
|
214659_x_at |
0.505 |
6.421 |
2.230 |
4.123e-02 |
0.571 |
-3.745 |
YLPM1 |
YLP motif containing 1 |
14 |
74299821 |
AC007956 |
56252 |
14q24.3 |
Hs.531111 |
11 |
molecular_function cellular_component nucleus biological_process nuclear speck |
|
235054_at |
0.414 |
6.579 |
2.764 |
1.433e-02 |
0.447 |
-2.861 |
NUDT16 |
nudix (nucleoside diphosphate linked moiety X)-type motif 16 |
3 |
132583396 |
BF941983 |
131870 |
3q22.1 |
Hs.591313 |
5 |
magnesium ion binding RNA binding nucleus nucleoplasm nucleolus hydrolase activity manganese ion binding |
|
236860_at |
NPY6R |
neuropeptide Y receptor Y6 (pseudogene) |
5 |
137171360 |
BF968482 |
4888 |
5q31 |
Hs.643466 Hs.713225 |
4 |
peptide YY receptor activity receptor activity G-protein coupled receptor activity integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway membrane |
|
226828_s_at |
HEYL |
hairy/enhancer-of-split related with YRPW motif-like |
1 |
-39861689 |
AL040198 |
26508 |
1p34.3 |
Hs.472566 |
10 |
transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent Notch signaling pathway multicellular organismal development nervous system development |
|
224614_at |
0.355 |
6.007 |
2.488 |
2.492e-02 |
0.513 |
-3.327 |
DYNC1LI2 |
dynein, cytoplasmic 1, light intermediate chain 2 |
16 |
-65312299 |
AK024863 |
1783 |
16q22.1 |
Hs.369068 |
10 |
nucleotide binding motor activity ATP binding cytoplasmic dynein complex microtubule |
|
201662_s_at |
ACSL3 |
acyl-CoA synthetase long-chain family member 3 |
2 |
223433975 |
D89053 |
2181 |
2q34-q35 |
Hs.655772 |
20 |
nucleotide binding magnesium ion binding fatty-acyl-CoA synthase activity long-chain-fatty-acid-CoA ligase activity protein binding ATP binding mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum microsome lipid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane ligase activity |
Fatty acid metabolism Metabolic pathways PPAR signaling pathway Adipocytokine signaling pathway |
1560069_at |
PLEKHM3 |
pleckstrin homology domain containing, family M, member 3 |
2 |
-208394257 |
BC020812 |
389072 |
2q33.3 |
Hs.159188 Hs.709906 |
3 |
intracellular signaling cascade zinc ion binding diacylglycerol binding metal ion binding |
|
212480_at |
0.267 |
6.843 |
3.022 |
8.473e-03 |
0.388 |
-2.415 |
CYTSA |
cytospin A |
22 |
22996785 |
AB002374 |
23384 |
22q11.23 |
Hs.474384 |
6 |
cell cycle cell division |
|
221959_at |
0.348 |
5.923 |
2.936 |
1.010e-02 |
0.415 |
-2.564 |
FAM110B |
family with sequence similarity 110, member B |
8 |
59069666 |
BE672313 |
90362 |
8q12.1 |
Hs.154652 |
7 |
cytoplasm mitochondrion centrosome |
|
211670_x_at |
SSX3 |
synovial sarcoma, X breakpoint 3 |
X |
-48092637, -48090806 |
S82471 |
10214 |
Xp11.23 |
Hs.558445 |
7 |
nucleic acid binding intracellular nucleus regulation of transcription, DNA-dependent |
|
233535_at |
-0.270 |
4.652 |
-2.404 |
2.937e-02 |
0.536 |
-3.464 |
ATP13A4 |
ATPase type 13A4 |
3 |
-194602559 |
AL512736 |
84239 |
3q29 |
Hs.674423 |
4 |
nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity |
|
206993_at |
0.769 |
7.515 |
2.981 |
9.221e-03 |
0.400 |
-2.487 |
ATP5S |
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) |
14 |
49848796, 49848796 |
NM_015684 |
27109 |
14q21.3 |
Hs.438489 |
12 |
mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o) |
|
225297_at |
0.580 |
6.442 |
2.373 |
3.121e-02 |
0.543 |
-3.515 |
HAUS1 |
HAUS augmin-like complex, subunit 1 |
18 |
41938295 |
AV715391 |
115106 |
18q21.1 |
Hs.436617 |
7 |
cytoplasm centrosome spindle microtubule cell cycle mitosis cell division HAUS complex |
|
203223_at |
RABEP1 |
rabaptin, RAB GTPase binding effector protein 1 |
17 |
5126281 |
NM_004703 |
9135 |
17p13.2 |
Hs.584784 Hs.592121 |
19 |
GTPase activator activity protein binding cytoplasm early endosome endocytosis apoptosis membrane fusion growth factor activity protein transport recycling endosome |
Endocytosis |
223652_at |
AS3MT |
arsenic (+3 oxidation state) methyltransferase |
10 |
104619199 |
AF226730 |
57412 |
10q24.32 |
Hs.34492 |
24 |
soluble fraction cytoplasm cytosol metabolic process methyltransferase activity toxin metabolic process transferase activity arsonoacetate metabolic process arsenite methyltransferase activity methylarsonite methyltransferase activity response to arsenic |
|
217995_at |
0.364 |
9.138 |
2.248 |
3.982e-02 |
0.568 |
-3.717 |
SQRDL |
sulfide quinone reductase-like (yeast) |
15 |
43714547 |
NM_021199 |
58472 |
15q15 |
Hs.511251 |
6 |
mitochondrion mitochondrial inner membrane oxidoreductase activity oxidation reduction |
|
204260_at |
2.511 |
4.431 |
3.259 |
5.205e-03 |
0.348 |
-2.001 |
CHGB |
chromogranin B (secretogranin 1) |
20 |
5839973 |
NM_001819 |
1114 |
20pter-p12 |
Hs.516874 |
35 |
hormone activity protein binding extracellular region |
|
205249_at |
EGR2 |
early growth response 2 |
10 |
-64241765, -64241765 |
NM_000399 |
1959 |
10q21.1 |
Hs.1395 |
41 |
transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent learning or memory rhythmic behavior motor axon guidance zinc ion binding Schwann cell differentiation rhombomere 3 development facial nerve structural organization rhombomere 3 formation rhombomere 5 formation regulation of ossification response to insulin stimulus brain segmentation myelination positive regulation of transcription from RNA polymerase II promoter metal ion binding regulation of neuronal synaptic plasticity |
|
237785_at |
ASB14 |
ankyrin repeat and SOCS box-containing 14 |
3 |
-57277418, -57277418 |
AI806707 |
142686 |
3p21.1 |
Hs.665154 Hs.703052 |
4 |
intracellular signaling cascade |
|
232432_s_at |
0.491 |
4.678 |
2.979 |
9.253e-03 |
0.400 |
-2.490 |
SLC30A5 |
solute carrier family 30 (zinc transporter), member 5 |
5 |
68425573, 68425637 |
AK022818 |
64924 |
5q12.1 |
Hs.631975 |
10 |
zinc ion transmembrane transporter activity membrane fraction Golgi apparatus integral to plasma membrane cation transport cobalt ion transport zinc ion transport cellular zinc ion homeostasis zinc ion binding cation transmembrane transporter activity response to zinc ion regulation of proton transport membrane apical plasma membrane secretory granule |
|
238088_at |
-0.400 |
3.827 |
-3.084 |
7.460e-03 |
0.376 |
-2.307 |
LOC100129194 |
hypothetical LOC100129194 |
3 |
|
BF511954 |
100129194 |
3p22.3 |
|
|
|
|
228076_s_at |
NOL6 |
nucleolar protein family 6 (RNA-associated) |
9 |
-33451350 |
BE780892 |
65083 |
9p13.3 |
Hs.493709 |
10 |
condensed nuclear chromosome RNA binding nucleus nucleolus small nucleolar ribonucleoprotein complex |
|
239126_at |
C19orf23 |
chromosome 19 open reading frame 23 |
19 |
-1218470 |
AA012950 |
148046 |
19p13.3 |
Hs.438829 |
2 |
|
|
218107_at |
0.571 |
7.763 |
3.744 |
1.911e-03 |
0.273 |
-1.149 |
WDR26 |
WD repeat domain 26 |
1 |
-222639467 |
NM_025160 |
80232 |
1q42.11-q42.12 |
Hs.497873 |
8 |
cytoplasm |
|
224053_s_at |
SLC4A9 |
solute carrier family 4, sodium bicarbonate cotransporter, member 9 |
5 |
139719970 |
AF336237 |
83697 |
5q31 |
Hs.550313 |
3 |
transporter activity inorganic anion exchanger activity anion transport anion transmembrane transporter activity antiporter activity membrane integral to membrane apical part of cell |
|
230789_at |
0.464 |
4.521 |
2.234 |
4.087e-02 |
0.570 |
-3.738 |
ZNF280B |
zinc finger protein 280B |
22 |
-21168771 |
AI015954 |
140883 |
22q11.22 |
Hs.43834 |
6 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
204000_at |
GNB5 |
guanine nucleotide binding protein (G protein), beta 5 |
15 |
-50200414, -50200414 |
NM_016194 |
10681 |
15q21.2 |
Hs.155090 |
26 |
GTPase activity signal transducer activity protein binding nucleus heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway |
Chemokine signaling pathway |
220816_at |
LPAR3 |
lysophosphatidic acid receptor 3 |
1 |
-85051673 |
NM_012152 |
23566 |
1p22.3 |
Hs.674915 |
19 |
activation of MAPK activity lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger elevation of cytosolic calcium ion concentration synaptic transmission lipid binding bleb formation positive regulation of MAPKKK cascade |
Neuroactive ligand-receptor interaction |
219050_s_at |
ZNHIT2 |
zinc finger, HIT type 2 |
11 |
-64640450 |
NM_014205 |
741 |
11q13 |
Hs.121025 |
7 |
zinc ion binding metal ion binding |
|
213547_at |
CAND2 |
cullin-associated and neddylation-dissociated 2 (putative) |
3 |
12813170 |
AB014567 |
23066 |
3p25.2 |
Hs.343664 |
7 |
intracellular nucleus transcription activator activity TATA-binding protein binding modification-dependent protein catabolic process regulation of transcription |
|
236262_at |
MMRN2 |
multimerin 2 |
10 |
-88685279 |
AA025351 |
79812 |
10q23.2 |
Hs.524479 Hs.719260 |
7 |
extracellular region basement membrane extracellular space |
|
226792_s_at |
KIFC2 |
kinesin family member C2 |
8 |
145662545 |
BF515031 |
90990 |
8q24.3 |
Hs.528713 |
7 |
nucleotide binding microtubule motor activity protein binding ATP binding microtubule microtubule-based movement |
|
230908_at |
TACR1 |
tachykinin receptor 1 |
2 |
-75131671, -75127097 |
AA461490 |
6869 |
2p12 |
Hs.633301 |
86 |
receptor activity G-protein coupled receptor activity tachykinin receptor activity protein binding plasma membrane integral to plasma membrane inflammatory response signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger tachykinin receptor signaling pathway mechanosensory behavior detection of abiotic stimulus |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
235198_at |
OSTM1 |
osteopetrosis associated transmembrane protein 1 |
6 |
-108469305 |
AV713913 |
28962 |
6q21 |
Hs.226780 Hs.706947 Hs.719130 |
16 |
protein binding cytosol membrane integral to membrane osteoclast differentiation |
|
203395_s_at |
HES1 |
hairy and enhancer of split 1, (Drosophila) |
3 |
195336627 |
NM_005524 |
3280 |
3q28-q29 |
Hs.250666 |
44 |
in utero embryonic development liver development DNA binding nucleus cytoplasm regulation of transcription, DNA-dependent cell adhesion positive regulation of cell proliferation positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter transcription repressor activity midbrain-hindbrain boundary morphogenesis oculomotor nerve development trochlear nerve development hindbrain morphogenesis neural tube development pituitary gland development lung development midbrain development auditory receptor cell fate determination cell fate commitment negative regulation of auditory receptor cell differentiation negative regulation of neuron differentiation cell maturation cell morphogenesis involved in neuron differentiation regulation of neurogenesis regulation of timing of neuron differentiation |
Notch signaling pathway Maturity onset diabetes of the young |
224677_x_at |
0.272 |
8.682 |
2.593 |
2.020e-02 |
0.493 |
-3.151 |
C11orf31 |
chromosome 11 open reading frame 31 |
11 |
57265297 |
AV729234 |
280636 |
11q12.1 |
Hs.655373 Hs.719147 |
6 |
selenium binding cell redox homeostasis |
|
200977_s_at |
0.426 |
9.292 |
2.536 |
2.264e-02 |
0.501 |
-3.246 |
TAX1BP1 |
Tax1 (human T-cell leukemia virus type I) binding protein 1 |
7 |
27746262 |
AF090891 |
8887 |
7p15 |
Hs.34576 |
21 |
intracellular apoptosis anti-apoptosis zinc ion binding identical protein binding |
|
222234_s_at |
0.594 |
5.614 |
3.017 |
8.565e-03 |
0.390 |
-2.425 |
DBNDD1 |
dysbindin (dystrobrevin binding protein 1) domain containing 1 |
16 |
-88598779, -88598779 |
AK022644 |
79007 |
16q24.3 |
Hs.301394 |
5 |
protein binding cytoplasm |
|
209406_at |
BAG2 |
BCL2-associated athanogene 2 |
6 |
57145062 |
AF095192 |
9532 |
6p12.1-p11.2 |
Hs.719303 |
16 |
protein binding protein folding apoptosis protein metabolic process |
|
235779_at |
LOC284408 |
hypothetical protein LOC284408 |
19 |
|
AW467077 |
284408 |
19q13.13 |
Hs.570010 |
1 |
|
|
212310_at |
MIA3 |
melanoma inhibitory activity family, member 3 |
1 |
220858066 |
D87742 |
375056 |
1q41 |
Hs.118474 |
13 |
positive regulation of leukocyte migration protein binding endoplasmic reticulum endoplasmic reticulum membrane exocytosis negative regulation of cell adhesion protein transport membrane integral to membrane negative regulation of cell migration wound healing |
|
242492_at |
CLNS1A |
chloride channel, nucleotide-sensitive, 1A |
11 |
-77004844 |
AA412065 |
1207 |
11q13.5-q14 |
Hs.430733 Hs.598033 |
24 |
spliceosomal snRNP biogenesis nucleus cytoplasm cytosol cytoskeleton plasma membrane transport chloride transport cell volume homeostasis blood circulation |
|
236008_at |
LOC100128909 |
similar to hCG1817494 |
9 |
|
BF510209 |
100128909 |
9q22.2-q22.31 |
Hs.535950 |
|
|
|
204067_at |
-0.255 |
7.561 |
-2.240 |
4.040e-02 |
0.569 |
-3.729 |
SUOX |
sulfite oxidase |
12 |
54677309 |
AA129776 |
6821 |
12q13.2 |
Hs.558403 |
23 |
mitochondrion mitochondrial intermembrane space cytosol response to nutrient sulfite oxidase activity electron carrier activity oxidoreductase activity heme binding molybdenum ion binding molybdopterin cofactor binding metal ion binding oxidation reduction |
Sulfur metabolism |
227718_at |
PURB |
purine-rich element binding protein B |
7 |
-44882416 |
BF337790 |
5814 |
7p13 |
Hs.349150 Hs.596321 |
13 |
translation repressor activity, nucleic acid binding double-stranded DNA binding single-stranded DNA binding transcription factor activity mRNA binding nucleus DNA replication factor A complex transcription factor binding specific transcriptional repressor activity purine-rich negative regulatory element binding regulation of transcription regulation of myeloid cell differentiation negative regulation of transcription, DNA-dependent SMAD binding |
|
211866_x_at |
-0.272 |
5.244 |
-2.418 |
2.860e-02 |
0.532 |
-3.442 |
HFE |
hemochromatosis |
6 |
26195487 |
AF079409 |
3077 |
6p21.3 |
Hs.233325 |
592 |
antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome |
|
201704_at |
0.234 |
7.271 |
2.322 |
3.451e-02 |
0.553 |
-3.598 |
ENTPD6 |
ectonucleoside triphosphate diphosphohydrolase 6 (putative function) |
20 |
25124338 |
NM_001247 |
955 |
20p11.2-p11.22 |
Hs.500375 |
15 |
magnesium ion binding calcium ion binding extracellular region Golgi apparatus membrane integral to membrane hydrolase activity nucleoside-diphosphatase activity |
Purine metabolism Pyrimidine metabolism |
204168_at |
MGST2 |
microsomal glutathione S-transferase 2 |
4 |
140806371 |
NM_002413 |
4258 |
4q28.3 |
Hs.81874 |
11 |
glutathione transferase activity membrane fraction endoplasmic reticulum microsome signal transduction cell-cell signaling enzyme activator activity membrane integral to membrane transferase activity leukotriene biosynthetic process |
Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 |
228764_s_at |
MDP1 |
magnesium-dependent phosphatase 1 |
14 |
-23752997 |
AI813313 |
145553 |
14q12 |
Hs.220963 |
5 |
magnesium ion binding protein tyrosine phosphatase activity hydrolase activity |
|
241937_s_at |
0.521 |
4.444 |
2.472 |
2.569e-02 |
0.517 |
-3.352 |
WDR4 |
WD repeat domain 4 |
21 |
-43142404, -43136272 |
AA577678 |
10785 |
21q22.3 |
Hs.248815 |
10 |
protein binding nucleus nucleoplasm cytoplasm tRNA modification tRNA (guanine-N7-)-methyltransferase activity |
|
206245_s_at |
0.720 |
6.814 |
2.742 |
1.498e-02 |
0.453 |
-2.898 |
IVNS1ABP |
influenza virus NS1A binding protein |
1 |
-183532144 |
NM_006469 |
10625 |
1q25.1-q31.1 |
Hs.497183 |
9 |
protein binding nucleus nucleoplasm transcription factor complex spliceosomal complex cytoplasm cytoskeleton transcription from RNA polymerase III promoter RNA splicing response to virus interspecies interaction between organisms |
|
224090_s_at |
TNFRSF19 |
tumor necrosis factor receptor superfamily, member 19 |
13 |
23042722, 23051638 |
AB040434 |
55504 |
13q12.11-q12.3 |
Hs.149168 |
14 |
receptor activity tumor necrosis factor receptor activity protein binding mitochondrion apoptosis induction of apoptosis JNK cascade membrane integral to membrane |
Cytokine-cytokine receptor interaction |
218029_at |
FAM65A |
family with sequence similarity 65, member A |
16 |
66120254 |
NM_024519 |
79567 |
16q22.1 |
Hs.152717 |
5 |
binding |
|
213578_at |
BMPR1A |
bone morphogenetic protein receptor, type IA |
10 |
88506375 |
AI678679 |
657 |
10q22.3 |
Hs.524477 |
70 |
nucleotide binding magnesium ion binding mesoderm formation Mullerian duct regression positive regulation of mesenchymal cell proliferation protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity ATP binding plasma membrane plasma membrane caveola protein amino acid phosphorylation immune response transforming growth factor beta receptor signaling pathway pattern specification process ectoderm development heart development dorsal/ventral axis specification anterior/posterior pattern formation positive regulation of pathway-restricted SMAD protein phosphorylation integral to membrane transferase activity stem cell maintenance manganese ion binding cell differentiation lung development positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway hindlimb morphogenesis odontogenesis of dentine-containing tooth protein homodimerization activity positive regulation of osteoblast differentiation SMAD binding mesendoderm development embryonic morphogenesis positive regulation of epithelial cell proliferation negative regulation of neurogenesis cartilage development palate development positive regulation of SMAD protein nuclear translocation |
Cytokine-cytokine receptor interaction TGF-beta signaling pathway |
200096_s_at |
0.264 |
9.746 |
2.936 |
1.010e-02 |
0.415 |
-2.564 |
ATP6V0E1 |
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
5 |
172343368 |
AI862255 |
8992 |
5q35.1 |
Hs.484188 |
18 |
transporter activity membrane fraction ion transport vacuolar acidification ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport membrane integral to membrane cell growth hydrolase activity proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions proton-transporting ATPase activity, rotational mechanism |
Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection |
210295_at |
-0.186 |
4.509 |
-2.381 |
3.076e-02 |
0.542 |
-3.502 |
MAGEA10 |
melanoma antigen family A, 10 |
X |
-151053563 |
BC004105 |
4109 |
Xq28 |
Hs.18048 |
6 |
|
|
213742_at |
SFRS11 |
splicing factor, arginine/serine-rich 11 |
1 |
70443952 |
AW241752 |
9295 |
1p31 |
Hs.479693 |
13 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleolus RNA splicing |
|
208331_at |
-0.341 |
2.663 |
-3.286 |
4.919e-03 |
0.341 |
-1.953 |
BPY2 |
basic charge, Y-linked, 2 |
Y |
-25586437, 23539797, 25173538 |
NM_004678 |
9083 |
Yq11 |
Hs.664724 |
7 |
|
|
218847_at |
-0.392 |
5.262 |
-2.922 |
1.040e-02 |
0.418 |
-2.590 |
IGF2BP2 |
insulin-like growth factor 2 mRNA binding protein 2 |
3 |
-186844220 |
NM_006548 |
10644 |
3q27.2 |
Hs.35354 |
55 |
nucleotide binding RNA binding protein binding nucleus cytoplasm biological_process anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process cytoskeletal part translation regulator activity mRNA 5'-UTR binding |
|
210960_at |
ADRA1D |
adrenergic, alpha-1D-, receptor |
20 |
-4149277 |
M76446 |
146 |
20p13 |
Hs.557 |
30 |
negative regulation of the force of heart contraction during baroreceptor response to increased systemic arterial blood pressure norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure receptor activity G-protein coupled receptor activity adrenoceptor activity alpha1-adrenergic receptor activity plasma membrane integral to plasma membrane DNA metabolic process signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger cell-cell signaling multicellular organismal development positive regulation of cell proliferation |
Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction |
211760_s_at |
-0.497 |
4.136 |
-3.072 |
7.638e-03 |
0.378 |
-2.327 |
VAMP4 |
vesicle-associated membrane protein 4 |
1 |
-169938782 |
BC005974 |
8674 |
1q24-q25 |
Hs.6651 |
15 |
Golgi membrane lysosome endosome Golgi apparatus membrane integral to membrane vesicle-mediated transport |
SNARE interactions in vesicular transport |
226640_at |
DAGLB |
diacylglycerol lipase, beta |
7 |
-6415272 |
AA015606 |
221955 |
7p22.1 |
Hs.487498 |
9 |
triacylglycerol lipase activity calcium ion binding plasma membrane integral to membrane lipid catabolic process hydrolase activity |
|
216718_at |
C1orf46 |
chromosome 1 open reading frame 46 |
1 |
|
AF005082 |
388699 |
1q21.3 |
Hs.516420 |
1 |
|
|
1567358_at |
NAV2 |
neuron navigator 2 |
11 |
19328846, 19691456, 20001211 |
AJ488204 |
89797 |
11p15.1 |
Hs.502116 Hs.551898 Hs.639427 Hs.639428 |
18 |
nucleotide binding helicase activity ATP binding nucleus nucleolus cytoplasm hydrolase activity |
|
210767_at |
NF2 |
neurofibromin 2 (merlin) |
22 |
28329544, 28329544 |
BC003112 |
4771 |
22q12.2 |
Hs.187898 |
131 |
mesoderm formation ruffle negative regulation of cell-matrix adhesion nucleus nucleolus cytoplasm early endosome cytoskeleton plasma membrane adherens junction negative regulation of protein kinase activity ectoderm development cytoskeletal protein binding negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell proliferation Schwann cell proliferation extrinsic to membrane negative regulation of cell-cell adhesion lamellipodium actin cytoskeleton organization filopodium negative regulation of cell migration cleavage furrow odontogenesis of dentine-containing tooth negative regulation of tyrosine phosphorylation of Stat3 protein negative regulation of tyrosine phosphorylation of Stat5 protein negative regulation of MAPKKK cascade cell-cell junction organization negative regulation of JAK-STAT cascade perinuclear region of cytoplasm positive regulation of stress fiber formation |
|
226018_at |
0.535 |
7.080 |
2.262 |
3.873e-02 |
0.567 |
-3.694 |
C7orf41 |
chromosome 7 open reading frame 41 |
7 |
30141076 |
W73230 |
222166 |
7p14.3 |
Hs.200100 |
4 |
|
|
212615_at |
CHD9 |
chromodomain helicase DNA binding protein 9 |
16 |
51646445 |
AI742305 |
80205 |
16q12.2 |
Hs.59159 Hs.622347 |
10 |
nucleotide binding chromatin DNA binding chromatin binding helicase activity protein binding ATP binding nucleus cytoplasm chromatin assembly or disassembly chromatin modification hydrolase activity regulation of transcription |
|
240862_at |
RASGRP4 |
RAS guanyl releasing protein 4 |
19 |
-43591537 |
AA923524 |
115727 |
19q13.1 |
Hs.130434 |
7 |
Ras guanyl-nucleotide exchange factor activity Ras guanyl-nucleotide exchange factor activity calcium ion binding intracellular membrane fraction membrane fraction soluble fraction soluble fraction cytoplasm plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway activation of phospholipase C activity zinc ion binding regulation of G-protein coupled receptor protein signaling pathway cell proliferation cell proliferation response to extracellular stimulus response to extracellular stimulus cell growth cell growth diacylglycerol binding myeloid cell differentiation GTP-dependent protein binding positive regulation of Ras protein signal transduction positive regulation of Ras protein signal transduction regulation of small GTPase mediated signal transduction |
MAPK signaling pathway |
219879_s_at |
C17orf53 |
chromosome 17 open reading frame 53 |
17 |
39574851 |
NM_024032 |
78995 |
17q21.31 |
Hs.437059 |
3 |
|
|
225797_at |
MRPL54 |
mitochondrial ribosomal protein L54 |
19 |
3713664 |
AV707568 |
116541 |
19p13.3 |
Hs.356578 |
5 |
mitochondrion ribosome |
|
1555781_at |
PQLC2 |
PQ loop repeat containing 2 |
1 |
19511326 |
BC015324 |
54896 |
1p36.13 |
Hs.647620 |
5 |
membrane integral to membrane |
|
202341_s_at |
0.333 |
5.699 |
2.863 |
1.172e-02 |
0.426 |
-2.691 |
TRIM2 |
tripartite motif-containing 2 |
4 |
154293719, 154345047 |
AA149745 |
23321 |
4q31.3 |
Hs.435711 |
6 |
protein binding intracellular cytoplasm biological_process zinc ion binding metal ion binding |
|
223286_at |
C17orf81 |
chromosome 17 open reading frame 81 |
17 |
7096095, 7096274 |
BC002762 |
23587 |
17p13.1 |
Hs.417029 |
8 |
protein binding cytoplasm regulation of transcription |
|
238076_at |
GATAD2B |
GATA zinc finger domain containing 2B |
1 |
-152043826 |
AI818098 |
57459 |
1q21.3 |
Hs.4779 Hs.596854 |
14 |
transcription factor activity protein binding nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding |
|
218196_at |
OSTM1 |
osteopetrosis associated transmembrane protein 1 |
6 |
-108469305 |
NM_014028 |
28962 |
6q21 |
Hs.226780 Hs.706947 Hs.719130 |
16 |
protein binding cytosol membrane integral to membrane osteoclast differentiation |
|
209103_s_at |
UFD1L |
ubiquitin fusion degradation 1 like (yeast) |
22 |
-17817463 |
BC001049 |
7353 |
22q11.21 |
Hs.474213 |
22 |
skeletal system development ubiquitin-specific protease activity protein binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process |
|
221045_s_at |
-0.797 |
7.315 |
-2.459 |
2.637e-02 |
0.521 |
-3.374 |
PER3 |
period homolog 3 (Drosophila) |
1 |
7767349 |
NM_016831 |
8863 |
1p36.23 |
Hs.162200 |
35 |
signal transducer activity nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction rhythmic process |
Circadian rhythm - mammal |
224736_at |
0.334 |
7.832 |
2.129 |
4.994e-02 |
0.591 |
-3.903 |
CCAR1 |
cell division cycle and apoptosis regulator 1 |
10 |
70150976 |
BE617899 |
55749 |
10q21.3 |
Hs.49853 |
18 |
nuclear mRNA splicing, via spliceosome nucleic acid binding nucleus cytoplasm Golgi apparatus apoptosis cell cycle perinuclear region of cytoplasm |
|
229266_at |
0.470 |
3.200 |
3.256 |
5.241e-03 |
0.348 |
-2.007 |
LOC284033 |
hypothetical LOC284033 |
17 |
|
AI138603 |
284033 |
17p12 |
Hs.592124 |
2 |
|
|
230002_at |
0.465 |
5.799 |
2.902 |
1.083e-02 |
0.421 |
-2.624 |
CLCC1 |
chloride channel CLIC-like 1 |
1 |
-109273652 |
AA406603 |
23155 |
1p13.3 |
Hs.658489 |
6 |
nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane |
|
210805_x_at |
RUNX1 |
runt-related transcription factor 1 |
21 |
-35115443, -35081967, -35081967 |
U19601 |
861 |
21q22.3 |
Hs.149261 Hs.612648 |
256 |
transcription factor activity protein binding ATP binding nucleus nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity positive regulation of granulocyte differentiation chloride ion binding positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter |
Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia |
236223_s_at |
RIT1 |
Ras-like without CAAX 1 |
1 |
-154134224 |
AL037450 |
6016 |
1q22 |
Hs.491234 |
17 |
nucleotide binding calmodulin binding GTP binding intracellular plasma membrane signal transduction small GTPase mediated signal transduction small GTPase mediated signal transduction |
|
239136_at |
hCG_1818231 |
hCG1818231 |
10 |
|
AI871120 |
728978 |
10q22.1 |
|
1 |
|
|
222437_s_at |
0.297 |
9.163 |
2.270 |
3.818e-02 |
0.565 |
-3.682 |
VPS24 |
vacuolar protein sorting 24 homolog (S. cerevisiae) |
2 |
-86584063 |
BC004419 |
51652 |
2p24.3-p24.1 |
Hs.591582 |
25 |
protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division |
Endocytosis |
208826_x_at |
0.308 |
10.976 |
3.204 |
5.826e-03 |
0.357 |
-2.097 |
HINT1 |
histidine triad nucleotide binding protein 1 |
5 |
-130522773, -130522773 |
U27143 |
3094 |
5q31.2 |
Hs.483305 |
26 |
protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity |
|
212245_at |
MCFD2 |
multiple coagulation factor deficiency 2 |
2 |
-46982518 |
AL567779 |
90411 |
2p21 |
Hs.293689 |
19 |
calcium ion binding extracellular region endoplasmic reticulum ER-Golgi intermediate compartment Golgi apparatus protein transport vesicle-mediated transport carboxylic acid metabolic process |
|
217835_x_at |
C20orf24 |
chromosome 20 open reading frame 24 |
20 |
34667580, 34667605 |
NM_018840 |
55969 |
20q11.23 |
Hs.584985 |
7 |
molecular_function protein binding cellular_component biological_process |
|
219804_at |
SYNPO2L |
synaptopodin 2-like |
10 |
-75074649, -75074649 |
NM_024875 |
79933 |
10q22.2 |
Hs.645273 |
4 |
actin binding protein binding cytoplasm cytoskeleton |
|
226267_at |
0.723 |
6.423 |
4.162 |
8.111e-04 |
0.214 |
-0.424 |
JDP2 |
Jun dimerization protein 2 |
14 |
74964261, 74964672, 74964812, 74968589 |
AA716425 |
122953 |
14q24.3 |
Hs.196482 |
15 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity nucleus regulation of transcription, DNA-dependent transcription repressor activity sequence-specific DNA binding protein dimerization activity |
|
202978_s_at |
0.482 |
5.295 |
3.052 |
7.963e-03 |
0.384 |
-2.363 |
CREBZF |
CREB/ATF bZIP transcription factor |
11 |
-85046257 |
AW204564 |
58487 |
11q14 |
Hs.535319 Hs.595940 Hs.714910 |
12 |
transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent response to virus negative regulation of transcription specific transcriptional repressor activity sequence-specific DNA binding negative regulation of gene expression, epigenetic regulation of transcription factor activity |
|
209842_at |
SOX10 |
SRY (sex determining region Y)-box 10 |
22 |
-36698264 |
AI367319 |
6663 |
22q13.1 |
Hs.376984 |
46 |
in utero embryonic development DNA binding chromatin binding RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity nucleus cytoplasm peripheral nervous system development cell differentiation melanocyte differentiation identical protein binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter cell maturation enteric nervous system development gut morphogenesis developmental growth oligodendrocyte differentiation |
|
204829_s_at |
FOLR2 |
folate receptor 2 (fetal) |
11 |
71605466 |
NM_000803 |
2350 |
11q13.3-q13.5 |
Hs.433159 |
24 |
receptor activity folic acid binding extracellular region membrane fraction plasma membrane folic acid transport anchored to membrane |
|
211075_s_at |
0.351 |
7.112 |
2.172 |
4.608e-02 |
0.582 |
-3.837 |
CD47 |
CD47 molecule |
3 |
-109244630 |
Z25521 |
961 |
3q13.1-q13.2 |
Hs.446414 |
68 |
protein binding plasma membrane plasma membrane integral to plasma membrane cell adhesion integrin-mediated signaling pathway positive regulation of cell proliferation positive regulation of cell-cell adhesion positive regulation of T cell activation thrombospondin receptor activity |
ECM-receptor interaction |
203528_at |
SEMA4D |
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
9 |
-91181971, -91165525 |
NM_006378 |
10507 |
9q22.2 |
Hs.494406 |
29 |
receptor activity receptor binding anti-apoptosis immune response cell adhesion multicellular organismal development nervous system development membrane integral to membrane cell differentiation positive regulation of axonogenesis |
Axon guidance |
220391_at |
ZBTB3 |
zinc finger and BTB domain containing 3 |
11 |
-62275012 |
NM_024784 |
79842 |
11q12.3 |
Hs.147554 |
5 |
DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
204219_s_at |
0.273 |
10.248 |
2.446 |
2.707e-02 |
0.525 |
-3.396 |
PSMC1 |
proteasome (prosome, macropain) 26S subunit, ATPase, 1 |
14 |
89792646 |
NM_002802 |
5700 |
14q32.11 |
Hs.356654 |
51 |
nucleotide binding proteasome complex protein binding ATP binding nucleus nucleolus cytoplasm cytosol hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
209311_at |
0.279 |
6.931 |
2.305 |
3.569e-02 |
0.556 |
-3.626 |
BCL2L2 |
BCL2-like 2 |
14 |
22845851 |
D87461 |
599 |
14q11.2-q12 |
Hs.410026 |
31 |
protein binding mitochondrion cytosol anti-apoptosis spermatogenesis membrane mitochondrial membrane regulation of apoptosis Sertoli cell proliferation |
|
238805_at |
0.756 |
5.372 |
4.038 |
1.045e-03 |
0.225 |
-0.637 |
C11orf52 |
chromosome 11 open reading frame 52 |
11 |
111294810 |
AA991551 |
91894 |
11q23.1 |
Hs.97013 |
3 |
|
|
234257_at |
TNS3 |
tensin 3 |
7 |
-47281276 |
AL137468 |
64759 |
7p12.3 |
Hs.520814 |
12 |
protein binding nucleus nucleolus cytoplasm plasma membrane focal adhesion positive regulation of cell proliferation cell migration cell junction lung alveolus development |
|
1556420_s_at |
YPEL2 |
yippee-like 2 (Drosophila) |
17 |
54763834 |
AK097253 |
388403 |
17q22 |
Hs.463613 |
5 |
nucleus nucleolus |
|
206976_s_at |
HSPH1 |
heat shock 105kDa/110kDa protein 1 |
13 |
-30608762 |
NM_006644 |
10808 |
13q12.3 |
Hs.36927 |
25 |
nucleotide binding ATP binding cytoplasm response to unfolded protein |
|
206974_at |
CXCR6 |
chemokine (C-X-C motif) receptor 6 |
3 |
45959976 |
NM_006564 |
10663 |
3p21 |
Hs.34526 |
37 |
G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity viral genome replication |
Cytokine-cytokine receptor interaction Chemokine signaling pathway |
208799_at |
0.217 |
10.104 |
2.284 |
3.717e-02 |
0.562 |
-3.660 |
PSMB5 |
proteasome (prosome, macropain) subunit, beta type, 5 |
14 |
-22564900, -22564900 |
BC004146 |
5693 |
14q11.2 |
Hs.422990 |
53 |
threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
202748_at |
GBP2 |
guanylate binding protein 2, interferon-inducible |
1 |
-89345897 |
NM_004120 |
2634 |
1p22.2 |
Hs.386567 |
13 |
nucleotide binding GTPase activity GTP binding plasma membrane immune response |
|
1565337_at |
DNAH6 |
dynein, axonemal, heavy chain 6 |
2 |
84597089 |
AJ132086 |
1768 |
2p11.2 |
Hs.249972 |
7 |
nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement ATPase activity dynein complex |
|
213999_at |
YIPF4 |
Yip1 domain family, member 4 |
2 |
32356461 |
BE999993 |
84272 |
2p22.3 |
Hs.468099 |
11 |
endoplasmic reticulum membrane integral to membrane |
|
231571_at |
LOC285827 |
hypothetical protein LOC285827 |
6 |
|
AA939337 |
285827 |
6p21.33 |
Hs.99161 |
1 |
|
|
203735_x_at |
-0.361 |
8.597 |
-2.196 |
4.401e-02 |
0.579 |
-3.799 |
PPFIBP1 |
PTPRF interacting protein, binding protein 1 (liprin beta 1) |
12 |
27568311, 27568311 |
N35896 |
8496 |
12p11.23-p11.22 |
Hs.172445 |
11 |
protein binding plasma membrane cell adhesion |
|
211462_s_at |
0.213 |
4.373 |
2.228 |
4.141e-02 |
0.572 |
-3.749 |
TBL1Y |
transducin (beta)-like 1Y-linked |
Y |
6838726 |
AF332222 |
90665 |
Yp11.2 |
Hs.664560 |
5 |
chromatin binding protein binding nucleus transcription factor complex regulation of transcription from RNA polymerase II promoter modification-dependent protein catabolic process regulation of transcription |
Wnt signaling pathway |
227798_at |
0.396 |
7.699 |
2.185 |
4.493e-02 |
0.581 |
-3.816 |
SMAD1 |
SMAD family member 1 |
4 |
146622400, 146623406 |
AU146891 |
4086 |
4q31 |
Hs.604588 |
118 |
MAPKKK cascade mesodermal cell fate commitment osteoblast fate commitment transcription factor activity RNA polymerase II transcription factor activity receptor signaling protein activity intracellular nucleus nucleoplasm transcription factor complex cytoplasm cytosol inflammatory response signal transduction transforming growth factor beta receptor signaling pathway SMAD protein complex assembly gamete generation negative regulation of cell proliferation embryonic pattern specification positive regulation of gene expression integral to membrane transcription activator activity BMP signaling pathway BMP signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity midbrain development hindbrain development primary microRNA processing homeostatic process identical protein binding positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter co-SMAD binding |
TGF-beta signaling pathway |
236939_at |
PTPLAD2 |
protein tyrosine phosphatase-like A domain containing 2 |
9 |
-20996364 |
AA687316 |
401494 |
9p21.3 |
Hs.716678 |
1 |
membrane integral to membrane |
|
207215_at |
GSTTP1 |
glutathione S-transferase theta pseudogene 1 |
22 |
-22670594 |
NM_015371 |
25774 |
22q12 |
Hs.652490 |
1 |
|
|
214395_x_at |
EEF1D |
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
8 |
-144733040, -144733040 |
AI335509 |
1936 |
8q24.3 |
Hs.333388 Hs.686554 |
42 |
translation elongation factor activity signal transducer activity protein binding cytosol eukaryotic translation elongation factor 1 complex translational elongation translational elongation positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
207826_s_at |
ID3 |
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
1 |
-23756995 |
NM_002167 |
3399 |
1p36.13-p36.12 |
Hs.76884 |
41 |
negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity nucleus nucleus regulation of DNA replication multicellular organismal development heart development transcription factor binding response to wounding negative regulation of transcription protein domain specific binding neuron differentiation epithelial cell differentiation positive regulation of apoptosis negative regulation of transcription factor activity |
TGF-beta signaling pathway |
218171_at |
VPS4B |
vacuolar protein sorting 4 homolog B (S. cerevisiae) |
18 |
-59207404 |
AF195514 |
9525 |
18q21.32-q21.33 |
Hs.126550 |
27 |
nucleotide binding ATP binding nucleus cytoplasm lysosome early endosome late endosome vacuolar membrane cytosol ATP catabolic process potassium ion transport endosome organization cell cycle protein C-terminus binding endosome membrane protein transport membrane endosome transport intracellular cholesterol transport endosome to lysosome transport via multivesicular body sorting pathway response to lipid ATPase activity, coupled cell division |
Endocytosis |
237256_at |
-0.246 |
4.427 |
-2.446 |
2.706e-02 |
0.525 |
-3.396 |
FBXL12 |
F-box and leucine-rich repeat protein 12 |
19 |
-9781942 |
AI479104 |
54850 |
19p13.2 |
Hs.12439 |
7 |
ubiquitin ligase complex cytoplasm ubiquitin-dependent protein catabolic process |
|
222212_s_at |
LASS2 |
LAG1 homolog, ceramide synthase 2 |
1 |
-149204272 |
AK001105 |
29956 |
1q21.3 |
Hs.713103 |
10 |
transcription factor activity protein binding nucleus endoplasmic reticulum regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sequence-specific DNA binding |
|
1562005_at |
RIN3 |
Ras and Rab interactor 3 |
14 |
92049877 |
BC034153 |
79890 |
14q32.12 |
Hs.326822 |
8 |
GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle |
|
239999_at |
C21orf34 |
chromosome 21 open reading frame 34 |
21 |
16364712, 16488569 |
N66393 |
388815 |
21q21.1 |
Hs.719301 |
5 |
|
|
213295_at |
0.654 |
7.041 |
2.596 |
2.008e-02 |
0.491 |
-3.145 |
CYLD |
cylindromatosis (turban tumor syndrome) |
16 |
49333461, 49333529 |
AA555096 |
1540 |
16q12.1 |
Hs.578973 |
54 |
structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm |
RIG-I-like receptor signaling pathway |
215606_s_at |
ERC1 |
ELKS/RAB6-interacting/CAST family member 1 |
12 |
970664 |
AB029004 |
23085 |
12p13.3 |
Hs.655744 Hs.658200 |
19 |
protein binding cytoplasm Golgi apparatus regulation of transcription, DNA-dependent I-kappaB phosphorylation multicellular organismal development IkappaB kinase complex protein transport Rab GTPase binding retrograde transport, endosome to Golgi presynaptic membrane leucine zipper domain binding positive regulation of anti-apoptosis positive regulation of NF-kappaB transcription factor activity |
|
1559244_at |
-0.311 |
3.914 |
-3.132 |
6.753e-03 |
0.368 |
-2.222 |
FMN2 |
formin 2 |
1 |
238321807 |
AF218941 |
56776 |
1q43 |
Hs.24889 |
7 |
molecular_function actin binding cellular_component meiotic metaphase I multicellular organismal development cellular component organization meiotic chromosome movement towards spindle pole actin cytoskeleton organization polar body extrusion after meiotic divisions oogenesis establishment of meiotic spindle localization |
Dorso-ventral axis formation |
220918_at |
0.936 |
5.060 |
2.860 |
1.180e-02 |
0.426 |
-2.697 |
C21orf96 |
chromosome 21 open reading frame 96 |
21 |
-35332104 |
NM_025143 |
80215 |
21q22.12 |
Hs.672131 |
4 |
cytosol |
|
203568_s_at |
0.601 |
6.390 |
3.584 |
2.663e-03 |
0.290 |
-1.430 |
TRIM38 |
tripartite motif-containing 38 |
6 |
26071049 |
NM_006355 |
10475 |
6p21.3 |
Hs.584851 |
7 |
signal transducer activity protein binding cellular_component intracellular zinc ion binding positive regulation of I-kappaB kinase/NF-kappaB cascade metal ion binding |
|
202651_at |
LPGAT1 |
lysophosphatidylglycerol acyltransferase 1 |
1 |
-209983422 |
NM_014873 |
9926 |
1q32 |
Hs.497674 |
6 |
molecular_function cytoplasm endoplasmic reticulum metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity |
|
1554168_a_at |
SH3KBP1 |
SH3-domain kinase binding protein 1 |
X |
-19462003, -19462003 |
AF542051 |
30011 |
Xp22.1-p21.3 |
Hs.719268 |
58 |
molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse |
Endocytosis |
203122_at |
TTC15 |
tetratricopeptide repeat domain 15 |
2 |
3362452 |
NM_016030 |
51112 |
2p25.3 |
Hs.252713 |
4 |
binding |
|
232173_at |
CLEC2L |
C-type lectin domain family 2, member L |
7 |
138859213 |
W60866 |
154790 |
7q34 |
Hs.57806 |
3 |
binding sugar binding membrane integral to membrane |
|
202059_s_at |
KPNA1 |
karyopherin alpha 1 (importin alpha 5) |
3 |
-123623437 |
NM_002264 |
3836 |
3q21 |
Hs.161008 |
92 |
regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
219925_at |
-0.199 |
3.493 |
-2.136 |
4.935e-02 |
0.590 |
-3.893 |
ZMYM6 |
zinc finger, MYM-type 6 |
1 |
-35224353 |
NM_007167 |
9204 |
1p34.2 |
Hs.533986 Hs.623978 Hs.675613 |
8 |
DNA binding nucleus nucleolus multicellular organismal development zinc ion binding metal ion binding |
|
209710_at |
GATA2 |
GATA binding protein 2 |
3 |
-129680954, -129680954, -129680954 |
AL563460 |
2624 |
3q21.3 |
Hs.367725 |
60 |
cell fate determination embryonic placenta development transcription factor activity nucleus nucleolus regulation of transcription, DNA-dependent transcription factor binding zinc ion binding positive regulation of specific transcription from RNA polymerase II promoter pituitary gland development neuron differentiation sequence-specific DNA binding positive regulation of angiogenesis metal ion binding cell maturation positive regulation of phagocytosis |
|
205796_at |
0.287 |
3.406 |
2.178 |
4.552e-02 |
0.581 |
-3.827 |
TCP11L1 |
t-complex 11 (mouse)-like 1 |
11 |
33017538, 33018136 |
NM_018393 |
55346 |
11p13 |
Hs.655341 |
4 |
|
|
210024_s_at |
UBE2E3 |
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) |
2 |
181553356, 181553586 |
AB017644 |
10477 |
2q32.1 |
Hs.470804 |
20 |
nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding nucleus cytoplasm ligase activity modification-dependent protein catabolic process regulation of growth post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
240363_at |
ANK1 |
ankyrin 1, erythrocytic |
8 |
-41629901, -41629901, -41629900 |
AW044553 |
286 |
8p11.1 |
Hs.654438 Hs.667377 |
49 |
structural constituent of cytoskeleton cytoplasm plasma membrane exocytosis cytoskeleton organization signal transduction cytoskeletal adaptor activity spectrin-associated cytoskeleton basolateral plasma membrane sarcoplasmic reticulum enzyme binding spectrin binding M band maintenance of epithelial cell apical/basal polarity |
|
229676_at |
0.444 |
6.728 |
2.846 |
1.214e-02 |
0.426 |
-2.721 |
MTPAP |
mitochondrial poly(A) polymerase |
10 |
-30638735 |
AA400998 |
55149 |
10p11.23 |
Hs.173946 |
13 |
nucleotide binding RNA binding polynucleotide adenylyltransferase activity ATP binding mitochondrion transcription mRNA processing transferase activity |
|
1569351_at |
-0.194 |
4.829 |
-2.199 |
4.374e-02 |
0.578 |
-3.794 |
SOBP |
sine oculis binding protein homolog (Drosophila) |
6 |
107918009 |
BC014859 |
55084 |
6q21 |
Hs.445244 |
4 |
zinc ion binding metal ion binding |
|
201079_at |
SYNGR2 |
synaptogyrin 2 |
17 |
73676265 |
NM_004710 |
9144 |
17q25.3 |
Hs.464210 Hs.708616 |
5 |
integral to plasma membrane membrane |
|
213992_at |
0.638 |
4.831 |
2.506 |
2.403e-02 |
0.509 |
-3.296 |
COL4A6 |
collagen, type IV, alpha 6 |
X |
-107285492, -107285492 |
AI889941 |
1288 |
Xq22 |
Hs.145586 |
35 |
extracellular matrix structural constituent protein binding extracellular region collagen collagen type IV cell adhesion extracellular matrix organization |
Focal adhesion ECM-receptor interaction Pathways in cancer Small cell lung cancer |
210384_at |
PRMT2 |
protein arginine methyltransferase 2 |
21 |
46879954 |
U79286 |
3275 |
21q22.3 |
Hs.154163 |
17 |
signal transducer activity nucleus protein amino acid methylation signal transduction methyltransferase activity transferase activity identical protein binding |
|
225186_at |
RAPH1 |
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
2 |
-204014436, -204006783 |
BF114947 |
65059 |
2q33 |
Hs.471162 |
13 |
nucleus cytoplasm cytoskeleton plasma membrane cell-matrix adhesion signal transduction lamellipodium filopodium |
|
217834_s_at |
SYNCRIP |
synaptotagmin binding, cytoplasmic RNA interacting protein |
6 |
-86380411, -86380411, -86374221, -86374221, -86374221, -86374221 |
NM_006372 |
10492 |
6q14-q15 |
Hs.571177 |
33 |
nucleotide binding RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm endoplasmic reticulum microsome mRNA processing poly(A) RNA binding RNA splicing interspecies interaction between organisms |
|
220589_s_at |
ITFG2 |
integrin alpha FG-GAP repeat containing 2 |
12 |
2792123 |
NM_018463 |
55846 |
12p13.33 |
Hs.446098 Hs.448720 |
2 |
|
|
206759_at |
FCER2 |
Fc fragment of IgE, low affinity II, receptor for (CD23) |
19 |
-7659643 |
NM_002002 |
2208 |
19p13.3 |
Hs.465778 |
71 |
receptor activity integrin binding binding sugar binding extracellular region plasma membrane integral to plasma membrane IgE binding positive regulation of nitric-oxide synthase activity positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase 2 biosynthetic process |
Hematopoietic cell lineage |
226938_at |
0.326 |
5.916 |
2.229 |
4.128e-02 |
0.571 |
-3.746 |
DCAF4 |
DDB1 and CUL4 associated factor 4 |
14 |
72462792 |
AA160604 |
26094 |
14q24.3 |
Hs.331491 |
4 |
|
|
215255_at |
IGSF9B |
immunoglobulin superfamily, member 9B |
11 |
-133290394 |
AB028953 |
22997 |
11q25 |
Hs.204121 |
3 |
|
|
227542_at |
SOCS6 |
suppressor of cytokine signaling 6 |
18 |
66107116 |
AU157543 |
9306 |
18q22.2 |
Hs.44439 |
13 |
protein binding cytoplasm defense response intracellular signaling cascade JAK-STAT cascade negative regulation of signal transduction modification-dependent protein catabolic process regulation of growth |
|
224827_at |
0.403 |
6.243 |
2.141 |
4.885e-02 |
0.590 |
-3.885 |
UBTD2 |
ubiquitin domain containing 2 |
5 |
-171569254 |
AK022894 |
92181 |
5q35.1 |
Hs.131570 Hs.716824 |
7 |
cytoplasm |
|
200033_at |
DDX5 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 |
17 |
-59924835 |
NM_004396 |
1655 |
17q21 |
Hs.279806 |
50 |
nucleotide binding RNA binding RNA helicase activity protein binding ATP binding nucleus spliceosomal complex nucleolus mRNA processing ATP-dependent helicase activity RNA splicing cell growth hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
|
1553422_s_at |
0.496 |
9.039 |
3.643 |
2.355e-03 |
0.284 |
-1.326 |
A2BP1 |
ataxin 2-binding protein 1 |
16 |
6009132, 6763810, 7322751 |
NM_145892 |
54715 |
16p13.3 |
Hs.459842 |
22 |
nucleotide binding RNA binding nucleus cytoplasm trans-Golgi network mRNA processing protein C-terminus binding RNA splicing RNA transport |
|
219827_at |
-0.837 |
8.156 |
-2.244 |
4.015e-02 |
0.569 |
-3.723 |
UCP3 |
uncoupling protein 3 (mitochondrial, proton carrier) |
11 |
-73391459, -73388975 |
NM_003356 |
7352 |
11q13 |
Hs.101337 Hs.621879 |
108 |
response to superoxide response to hypoxia transporter activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process transport mitochondrial transport respiratory gaseous exchange proton transport membrane integral to membrane oxidative phosphorylation uncoupler activity |
|
218208_at |
PQLC1 |
PQ loop repeat containing 1 |
18 |
-75763408 |
NM_025078 |
80148 |
18q23 |
Hs.288284 |
3 |
membrane integral to membrane |
|
213782_s_at |
MYOZ2 |
myozenin 2 |
4 |
120276386 |
BF939176 |
51778 |
4q26-q27 |
Hs.381047 |
16 |
protein binding cytoplasm biological_process actin cytoskeleton sarcomere Z disc protein phosphatase 2B binding |
|
202973_x_at |
FAM13A |
family with sequence similarity 13, member A |
4 |
-89866128, -89866128 |
NM_014883 |
10144 |
4q22.1 |
Hs.97270 |
7 |
|
|
202272_s_at |
FBXO28 |
F-box protein 28 |
1 |
222368413 |
NM_015176 |
23219 |
1q42.11 |
Hs.64691 Hs.713992 |
10 |
modification-dependent protein catabolic process |
|
226065_at |
-0.397 |
6.761 |
-2.582 |
2.065e-02 |
0.497 |
-3.169 |
PRICKLE1 |
prickle homolog 1 (Drosophila) |
12 |
-41138407, -41138407, -41138407 |
N98595 |
144165 |
12q12 |
Hs.524348 Hs.639400 |
14 |
nucleus cytoplasm cytosol zinc ion binding membrane nuclear membrane metal ion binding |
Wnt signaling pathway |
1564204_at |
FAM91A2 |
family with sequence similarity 91, member A2 |
1 |
|
AK090660 |
57234 |
1q21.1 |
Hs.710717 |
3 |
|
|
1559926_at |
-0.464 |
5.115 |
-2.411 |
2.900e-02 |
0.534 |
-3.453 |
LOC728353 |
hypothetical protein LOC728353 |
14 |
|
BC031683 |
728353 |
14q11.2 |
Hs.621210 |
|
|
|
1558174_at |
FAM43A |
family with sequence similarity 43, member A |
3 |
195887910 |
BM050463 |
131583 |
3q29 |
Hs.708232 |
5 |
|
|
218092_s_at |
AGFG1 |
ArfGAP with FG repeats 1 |
2 |
228045131 |
NM_004504 |
3267 |
2q36.3 |
Hs.352962 |
29 |
DNA binding RNA binding protein binding nucleus nuclear pore Golgi apparatus mRNA export from nucleus transport multicellular organismal development spermatogenesis ARF GTPase activator activity zinc ion binding cell differentiation cytoplasmic vesicle regulation of ARF GTPase activity metal ion binding |
|
201459_at |
0.470 |
8.232 |
2.701 |
1.626e-02 |
0.462 |
-2.968 |
RUVBL2 |
RuvB-like 2 (E. coli) |
19 |
54188967 |
NM_006666 |
10856 |
19q13.3 |
Hs.515846 |
46 |
nucleotide binding damaged DNA binding ATP-dependent DNA helicase activity ATP binding intracellular nucleus nucleoplasm cytoplasm DNA repair DNA recombination protein folding membrane nuclear matrix chromatin modification hydrolase activity ATPase activity NuA4 histone acetyltransferase complex regulation of growth identical protein binding histone H4 acetylation histone H2A acetylation regulation of transcription unfolded protein binding |
|
224755_at |
0.257 |
7.152 |
2.301 |
3.597e-02 |
0.557 |
-3.632 |
TM9SF3 |
transmembrane 9 superfamily member 3 |
10 |
-98267856 |
BE621524 |
56889 |
10q24.1 |
Hs.500674 |
5 |
binding membrane integral to membrane |
|
212733_at |
KIAA0226 |
KIAA0226 |
3 |
-198882710, -198882655 |
AI798908 |
9711 |
3q29 |
Hs.478868 |
6 |
|
|
204696_s_at |
-0.235 |
5.147 |
-2.487 |
2.495e-02 |
0.513 |
-3.328 |
CDC25A |
cell division cycle 25 homolog A (S. pombe) |
3 |
-48173671 |
NM_001789 |
993 |
3p21 |
Hs.437705 |
89 |
regulation of cyclin-dependent protein kinase activity protein tyrosine phosphatase activity protein binding cellular_component intracellular nucleoplasm DNA replication protein amino acid dephosphorylation cell cycle mitosis cell proliferation hydrolase activity cell division |
Cell cycle |
1553515_at |
MYEOV2 |
myeloma overexpressed 2 |
2 |
-240718914, -240714652 |
NM_138336 |
150678 |
2q37.3 |
Hs.293884 |
2 |
|
|
222980_at |
RAB10 |
RAB10, member RAS oncogene family |
2 |
26110477 |
AL136650 |
10890 |
2p23.3 |
Hs.467960 Hs.643072 |
14 |
nucleotide binding protein binding GTP binding Golgi apparatus plasma membrane small GTPase mediated signal transduction protein transport |
|
204919_at |
PRR4 |
proline rich 4 (lacrimal) |
12 |
-10889714, -10889714 |
NM_007244 |
11272 |
12p13 |
Hs.408153 |
7 |
extracellular region extracellular space visual perception |
|
207364_at |
-0.341 |
5.050 |
-2.716 |
1.579e-02 |
0.459 |
-2.943 |
TEX28 |
testis expressed 28 |
X |
-153152125 |
NM_001586 |
1527 |
Xq28 |
Hs.672606 |
7 |
molecular_function biological_process membrane integral to membrane |
|
212375_at |
EP400 |
E1A binding protein p400 |
12 |
131000460 |
AL563727 |
57634 |
12q24.33 |
Hs.699245 |
19 |
nucleotide binding DNA binding helicase activity ATP binding nucleus nucleolus chromatin modification hydrolase activity NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation |
|
218730_s_at |
OGN |
osteoglycin |
9 |
-94186069 |
NM_014057 |
4969 |
9q22 |
Hs.109439 |
24 |
molecular_function protein binding extracellular region proteinaceous extracellular matrix endoplasmic reticulum growth factor activity biological_process |
|
1567214_a_at |
0.548 |
6.760 |
3.630 |
2.419e-03 |
0.284 |
-1.349 |
PNN |
pinin, desmosome associated protein |
14 |
38714137 |
U59479 |
5411 |
14q21.1 |
Hs.409965 |
30 |
DNA binding structural molecule activity protein binding nucleus spliceosomal complex nucleolus cytoplasm intermediate filament plasma membrane mRNA processing cell adhesion RNA splicing nuclear speck desmosome regulation of transcription |
|
204990_s_at |
ITGB4 |
integrin, beta 4 |
17 |
71229110, 71232370 |
NM_000213 |
3691 |
17q25 |
Hs.632226 |
120 |
receptor activity protein binding cell communication cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
204268_at |
0.544 |
4.842 |
2.401 |
2.954e-02 |
0.536 |
-3.469 |
S100A2 |
S100 calcium binding protein A2 |
1 |
-151800208 |
NM_005978 |
6273 |
1q21 |
Hs.516484 |
45 |
calcium ion binding cellular_component endothelial cell migration |
|
243954_at |
-0.303 |
3.946 |
-2.324 |
3.438e-02 |
0.553 |
-3.595 |
LOC285286 |
hypothetical protein LOC285286 |
3 |
|
AI149729 |
285286 |
3p14.2 |
Hs.559386 |
1 |
|
|
205172_x_at |
CLTB |
clathrin, light chain (Lcb) |
5 |
-175752061 |
NM_007097 |
1212 |
4q2-q3 5q35 |
Hs.484241 |
17 |
structural molecule activity calcium ion binding protein binding intracellular protein transport membrane vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle |
Lysosome Endocytosis Huntington's disease |
230915_at |
DHRS7C |
dehydrogenase/reductase (SDR family) member 7C |
17 |
-9615479 |
AI741629 |
201140 |
17p13.1 |
Hs.61684 |
1 |
binding extracellular region oxidoreductase activity oxidation reduction |
|
221829_s_at |
TNPO1 |
transportin 1 |
5 |
72148173, 72179685 |
AI307759 |
3842 |
5q13.2 |
Hs.482497 |
58 |
protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
207468_s_at |
SFRP5 |
secreted frizzled-related protein 5 |
10 |
-99516497 |
NM_003015 |
6425 |
10q24.1 |
Hs.279565 |
14 |
protein binding extracellular region extracellular space apoptosis establishment or maintenance of cell polarity signal transduction multicellular organismal development visual perception anatomical structure morphogenesis Wnt receptor signaling pathway cell differentiation |
Wnt signaling pathway |
216992_s_at |
GRM8 |
glutamate receptor, metabotropic 8 |
7 |
-125865887, -125865887 |
AJ236922 |
2918 |
7q31.3-q32.1 |
Hs.449625 |
22 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway negative regulation of adenylate cyclase activity visual perception sensory perception of smell glutamate receptor activity negative regulation of cAMP biosynthetic process response to stimulus |
Neuroactive ligand-receptor interaction |
40225_at |
GAK |
cyclin G associated kinase |
4 |
-833064 |
D88435 |
2580 |
4p16 |
Hs.369607 |
19 |
nucleotide binding protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus focal adhesion protein amino acid phosphorylation cell cycle transferase activity cell junction heat shock protein binding perinuclear region of cytoplasm |
|
210170_at |
PDLIM3 |
PDZ and LIM domain 3 |
4 |
-186659844 |
BC001017 |
27295 |
4q35 |
Hs.85862 |
12 |
nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding |
|
219268_at |
ETNK2 |
ethanolamine kinase 2 |
1 |
-202366812 |
NM_018208 |
55224 |
1q32.1 |
Hs.497469 |
8 |
nucleotide binding in utero embryonic development placenta development choline kinase activity ethanolamine kinase activity ATP binding cellular_component phosphatidylethanolamine biosynthetic process biological_process post-embryonic development transferase activity multicellular organism growth |
Glycerophospholipid metabolism Metabolic pathways |
209896_s_at |
0.835 |
6.546 |
2.301 |
3.595e-02 |
0.557 |
-3.632 |
PTPN11 |
protein tyrosine phosphatase, non-receptor type 11 |
12 |
111340918 |
AF119855 |
5781 |
12q24 |
Hs.506852 Hs.646231 |
326 |
non-membrane spanning protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity protein binding cytoplasm cytosol protein amino acid dephosphorylation signal transduction hydrolase activity |
Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity Leukocyte transendothelial migration Neurotrophin signaling pathway Adipocytokine signaling pathway Epithelial cell signaling in Helicobacter pylori infection Renal cell carcinoma Chronic myeloid leukemia |
242902_at |
CYMP |
chymosin pseudogene |
1 |
110824910 |
AI479358 |
643160 |
1p13.3 |
Hs.532720 |
4 |
|
|
222830_at |
0.362 |
3.912 |
2.384 |
3.056e-02 |
0.541 |
-3.497 |
GRHL1 |
grainyhead-like 1 (Drosophila) |
2 |
10009242 |
BE566136 |
29841 |
2p25.1 |
Hs.418493 |
10 |
DNA binding nucleus nucleolus cytoplasm Golgi apparatus multicellular organismal development regulation of transcription |
|
219371_s_at |
KLF2 |
Kruppel-like factor 2 (lung) |
19 |
16296650 |
NM_016270 |
10365 |
19p13.13-p13.11 |
Hs.715677 |
38 |
transcription factor activity protein binding intracellular nucleus zinc ion binding transcription activator activity positive regulation of transcription metal ion binding |
|
1555741_at |
-0.270 |
3.722 |
-2.495 |
2.455e-02 |
0.513 |
-3.314 |
MRAP |
melanocortin 2 receptor accessory protein |
21 |
32585994, 32585994 |
AF483549 |
56246 |
21q22.1 |
Hs.584940 |
12 |
cytoplasm endoplasmic reticulum plasma membrane integral to membrane perinuclear region of cytoplasm |
|
225429_at |
PPP6C |
protein phosphatase 6, catalytic subunit |
9 |
-126948672 |
BF437011 |
5537 |
9q33.3 |
Hs.715605 |
16 |
G1/S transition of mitotic cell cycle protein serine/threonine phosphatase activity iron ion binding protein binding cytoplasm cytosol protein amino acid dephosphorylation cell cycle hydrolase activity manganese ion binding metal ion binding |
|
218295_s_at |
NUP50 |
nucleoporin 50kDa |
22 |
43938389, 43939215 |
NM_007172 |
10762 |
22q13.31 |
Hs.715672 |
15 |
protein binding nucleus nuclear pore nucleoplasm protein transport membrane intracellular transport mRNA transport intracellular protein transmembrane transport |
|
212470_at |
SPAG9 |
sperm associated antigen 9 |
17 |
-46394534 |
AB011088 |
9043 |
17q21.33 |
Hs.463439 |
22 |
acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm |
|
207315_at |
CD226 |
CD226 molecule |
18 |
-65681172 |
NM_006566 |
10666 |
18q22.3 |
Hs.660130 |
28 |
cytokine production positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of immunoglobulin mediated immune response receptor activity integrin binding integral to plasma membrane cell adhesion signal transduction cell recognition cell surface membrane protein kinase binding positive regulation of mast cell activation membrane raft cell adhesion molecule binding positive regulation of Fc receptor mediated stimulatory signaling pathway |
Cell adhesion molecules (CAMs) |
242499_at |
U2AF1 |
U2 small nuclear RNA auxiliary factor 1 |
21 |
-43386134 |
AA448694 |
7307 |
21q22.3 |
Hs.365116 |
47 |
nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex zinc ion binding RNA splicing Cajal body metal ion binding RS domain binding |
|
209785_s_at |
PLA2G4C |
phospholipase A2, group IVC (cytosolic, calcium-independent) |
19 |
-53242912 |
AF065214 |
8605 |
19q13.3 |
Hs.631562 |
22 |
phospholipid binding cytosol inflammatory response intracellular signaling cascade parturition metabolic process membrane lipid catabolic process hydrolase activity arachidonic acid metabolic process glycerophospholipid catabolic process calcium-independent phospholipase A2 activity |
|
219751_at |
SETD6 |
SET domain containing 6 |
16 |
57106883 |
NM_024860 |
79918 |
16q21 |
Hs.592060 |
5 |
|
|
200880_at |
0.536 |
7.305 |
2.868 |
1.161e-02 |
0.426 |
-2.683 |
DNAJA1 |
DnaJ (Hsp40) homolog, subfamily A, member 1 |
9 |
33015208 |
AL534104 |
3301 |
9p13-p12 |
Hs.445203 Hs.707338 |
27 |
protein folding response to unfolded protein spermatogenesis zinc ion binding membrane sperm motility androgen receptor signaling pathway heat shock protein binding metal ion binding low-density lipoprotein receptor binding unfolded protein binding |
|
206854_s_at |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
6 |
-91282073, -91282073 |
NM_003188 |
6885 |
6q16.1-q16.3 |
Hs.719192 |
114 |
nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation |
MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway |
203455_s_at |
SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
X |
23711195 |
NM_002970 |
6303 |
Xp22.1 |
Hs.28491 |
46 |
diamine N-acetyltransferase activity protein binding intracellular cytoplasm metabolic process acyltransferase activity transferase activity |
Arginine and proline metabolism Metabolic pathways |
209799_at |
0.619 |
3.757 |
3.598 |
2.587e-03 |
0.287 |
-1.406 |
PRKAA1 |
protein kinase, AMP-activated, alpha 1 catalytic subunit |
5 |
-40795237 |
AF100763 |
5562 |
5p12 |
Hs.43322 |
68 |
nucleotide binding activation of MAPK activity magnesium ion binding response to hypoxia protein serine/threonine kinase activity cAMP-dependent protein kinase activity protein binding ATP binding intracellular glucose metabolic process fatty acid biosynthetic process signal transduction transferase activity fatty acid oxidation positive regulation of cholesterol biosynthetic process positive regulation of anti-apoptosis negative regulation of glucosylceramide biosynthetic process |
Regulation of autophagy mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM) |
201417_at |
SOX4 |
SRY (sex determining region Y)-box 4 |
6 |
21701950 |
AL136179 |
6659 |
6p22.3 |
Hs.643910 |
35 |
pro-B cell differentiation transcription factor activity protein binding nucleus cytoplasm heart development positive regulation of cell proliferation positive regulation of Wnt receptor signaling pathway T cell differentiation exocrine pancreas development positive regulation of apoptosis negative regulation of apoptosis positive regulation of transcription, DNA-dependent protein stabilization Wnt receptor signaling pathway through beta-catenin |
|
214404_x_at |
SPDEF |
SAM pointed domain containing ets transcription factor |
6 |
-34613557 |
AI435670 |
25803 |
6p21.3 |
Hs.485158 |
21 |
transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development sequence-specific DNA binding |
|
205976_at |
FASTKD2 |
FAST kinase domains 2 |
2 |
207338356 |
NM_014929 |
22868 |
2q33.3 |
Hs.5930 |
8 |
protein kinase activity ATP binding apoptosis |
|
219317_at |
0.475 |
4.457 |
2.591 |
2.028e-02 |
0.494 |
-3.154 |
POLI |
polymerase (DNA directed) iota |
18 |
50049846 |
NM_007195 |
11201 |
18q21.1 |
Hs.438533 |
58 |
magnesium ion binding damaged DNA binding DNA-directed DNA polymerase activity protein binding intracellular nucleus nucleoplasm DNA replication DNA repair response to DNA damage stimulus transferase activity nucleotidyltransferase activity |
|
1554949_at |
-0.248 |
5.454 |
-2.351 |
3.259e-02 |
0.548 |
-3.551 |
LOC554174 |
hypothetical LOC554174 |
22 |
|
BC009388 |
554174 |
22q13.31 |
Hs.660824 |
1 |
|
|
225662_at |
ZAK |
sterile alpha motif and leucine zipper containing kinase AZK |
2 |
173648810, 173648810 |
H28667 |
51776 |
2q24.2 |
Hs.444451 |
24 |
cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis |
MAPK signaling pathway Tight junction |
227396_at |
0.562 |
5.515 |
2.478 |
2.543e-02 |
0.515 |
-3.344 |
PTPRJ |
protein tyrosine phosphatase, receptor type, J |
11 |
47958685, 47958685 |
AI631833 |
5795 |
11p11.2 |
Hs.318547 |
36 |
transmembrane receptor protein tyrosine phosphatase activity protein binding nucleus plasma membrane integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine kinase signaling pathway cell-cell signaling hydrolase activity cell junction |
Adherens junction |
229122_x_at |
C16orf35 |
chromosome 16 open reading frame 35 |
16 |
-75803, -75803 |
AI669063 |
8131 |
16p13.3 |
Hs.19699 |
6 |
molecular_function cellular_component biological_process |
|
227142_at |
PLEKHG5 |
pleckstrin homology domain containing, family G (with RhoGef domain) member 5 |
1 |
-6448738, -6448738, -6448738, -6448738, -6448738 |
AW274379 |
57449 |
1p36.31 |
Hs.284232 Hs.619982 |
7 |
signal transducer activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm cell death regulation of Rho protein signal transduction positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm |
|
231478_at |
-1.251 |
4.573 |
-2.647 |
1.816e-02 |
0.479 |
-3.061 |
PDE4C |
phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) |
19 |
-18179770, -18179770, -18179770 |
AI051127 |
5143 |
19p13.11 |
Hs.132584 |
13 |
3',5'-cyclic-AMP phosphodiesterase activity signal transduction hydrolase activity |
Purine metabolism |
227072_at |
RTTN |
rotatin |
18 |
-65822020 |
BG167480 |
25914 |
18q22.2 |
Hs.654809 |
3 |
binding multicellular organismal development determination of left/right symmetry |
|
201808_s_at |
ENG |
endoglin |
9 |
-129617111 |
BE732652 |
2022 |
9q33-q34.1 |
Hs.76753 |
164 |
chronological cell aging patterning of blood vessels heart looping transmembrane receptor activity transforming growth factor beta receptor, cytoplasmic mediator activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding protein binding galactose binding glycosaminoglycan binding glycosaminoglycan binding extracellular space membrane fraction cell adhesion heart development external side of plasma membrane positive regulation of pathway-restricted SMAD protein phosphorylation membrane integral to membrane regulation of transforming growth factor beta receptor signaling pathway central nervous system vasculogenesis positive regulation of BMP signaling pathway negative regulation of protein amino acid autophosphorylation type I transforming growth factor beta receptor binding type I transforming growth factor beta receptor binding protein homodimerization activity regulation of transcription activin binding smooth muscle tissue development artery morphogenesis venous blood vessel morphogenesis transforming growth factor beta binding transforming growth factor beta receptor complex |
|
204212_at |
ACOT8 |
acyl-CoA thioesterase 8 |
20 |
-43903767 |
NM_005469 |
10005 |
20q13.12 |
Hs.444776 |
18 |
carboxylesterase activity protein binding peroxisome lipid metabolic process acyl-CoA metabolic process peroxisome organization acyl-CoA thioesterase activity hydrolase activity choloyl-CoA hydrolase activity interspecies interaction between organisms |
|
219706_at |
0.380 |
6.858 |
2.587 |
2.045e-02 |
0.495 |
-3.161 |
C20orf29 |
chromosome 20 open reading frame 29 |
20 |
3749202 |
NM_018347 |
55317 |
20p13 |
Hs.104806 |
4 |
|
|
218206_x_at |
SCAND1 |
SCAN domain containing 1 |
20 |
-34004959 |
NM_016558 |
51282 |
20q11.1-q11.23 |
Hs.584909 |
14 |
transcription factor activity transcription coactivator activity nucleus regulation of transcription, DNA-dependent identical protein binding |
|
237142_at |
PPARA |
peroxisome proliferator-activated receptor alpha |
22 |
44925162 |
AI939604 |
5465 |
22q12-q13.1 22q13.31 |
Hs.103110 Hs.710044 |
260 |
response to hypoxia transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent lipid metabolic process drug binding zinc ion binding epidermis development negative regulation of specific transcription from RNA polymerase II promoter negative regulation of foam cell differentiation negative regulation of foam cell differentiation negative regulation of receptor biosynthetic process negative regulation of cholesterol storage negative regulation of sequestering of triglyceride fatty acid transport transcription activator activity regulation of fatty acid metabolic process positive regulation of fatty acid beta-oxidation wound healing sequence-specific DNA binding positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding |
PPAR signaling pathway Adipocytokine signaling pathway |
212881_at |
-0.340 |
5.743 |
-2.920 |
1.044e-02 |
0.418 |
-2.593 |
PIAS4 |
protein inhibitor of activated STAT, 4 |
19 |
3958748 |
AK022481 |
51588 |
19p13.3 |
Hs.105779 |
39 |
negative regulation of transcription from RNA polymerase II promoter DNA binding transcription corepressor activity protein binding nucleus nucleus zinc ion binding Wnt receptor signaling pathway nuclear matrix negative regulation of transcription negative regulation of transcription SUMO ligase activity modification-dependent protein catabolic process positive regulation of protein sumoylation metal ion binding |
Ubiquitin mediated proteolysis Jak-STAT signaling pathway Pathways in cancer Small cell lung cancer |
219232_s_at |
0.410 |
3.685 |
2.401 |
2.955e-02 |
0.536 |
-3.469 |
EGLN3 |
egl nine homolog 3 (C. elegans) |
14 |
-33463171 |
NM_022073 |
112399 |
14q13.1 |
Hs.135507 |
26 |
iron ion binding protein binding nucleus cytoplasm apoptosis oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction |
Pathways in cancer Renal cell carcinoma |
233339_s_at |
-0.283 |
4.975 |
-2.907 |
1.071e-02 |
0.420 |
-2.615 |
ARID1B |
AT rich interactive domain 1B (SWI1-like) |
6 |
157140777 |
AW024272 |
57492 |
6q25.1 |
Hs.291587 Hs.714899 |
22 |
DNA binding DNA binding transcription coactivator activity protein binding intracellular nucleus nucleolus cytoplasm SWI/SNF complex chromatin modification regulation of transcription chromatin-mediated maintenance of transcription |
|
212006_at |
0.351 |
8.019 |
2.729 |
1.539e-02 |
0.458 |
-2.921 |
UBXN4 |
UBX domain protein 4 |
2 |
136215658 |
AU149908 |
23190 |
2q21.3 |
Hs.591242 |
12 |
protein binding nucleus nuclear envelope endoplasmic reticulum response to unfolded protein membrane integral to membrane |
|
223082_at |
SH3KBP1 |
SH3-domain kinase binding protein 1 |
X |
-19462003, -19462003 |
AF230904 |
30011 |
Xp22.1-p21.3 |
Hs.719268 |
58 |
molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse |
Endocytosis |
1565797_at |
-0.204 |
4.239 |
-2.163 |
4.690e-02 |
0.583 |
-3.851 |
DUOX1 |
dual oxidase 1 |
15 |
43209483 |
BC030522 |
53905 |
15q15.3 |
Hs.272813 |
28 |
peroxidase activity calcium ion binding plasma membrane response to oxidative stress electron carrier activity integral to membrane NAD(P)H oxidase activity apical plasma membrane oxidoreductase activity cytokine-mediated signaling pathway heme binding cuticle development hormone biosynthetic process superoxide anion generation hydrogen peroxide catabolic process FAD binding NADP or NADPH binding hydrogen peroxide biosynthetic process response to cAMP response to cAMP oxidation reduction |
|
204843_s_at |
PRKAR2A |
protein kinase, cAMP-dependent, regulatory, type II, alpha |
3 |
-48763096 |
NM_004157 |
5576 |
3p21.3-p21.2 |
Hs.631923 |
81 |
nucleotide binding regulation of protein amino acid phosphorylation membrane fraction cytoplasm plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase regulator activity hormone-mediated signaling cAMP binding |
Apoptosis Insulin signaling pathway |
201133_s_at |
PJA2 |
praja ring finger 2 |
5 |
-108698308 |
AA142966 |
9867 |
5q21.3 |
Hs.483036 Hs.592564 |
10 |
protein binding cytoplasm endoplasmic reticulum Golgi apparatus plasma membrane zinc ion binding postsynaptic density ligase activity modification-dependent protein catabolic process cell junction synapse postsynaptic membrane metal ion binding |
|
227144_at |
C22orf9 |
chromosome 22 open reading frame 9 |
22 |
-43966786, -43966786 |
AA476916 |
23313 |
22q13.31 |
Hs.592207 |
10 |
protein binding |
|
223919_at |
TP53AIP1 |
tumor protein p53 regulated apoptosis inducing protein 1 |
11 |
-128310479 |
AB045831 |
63970 |
11q24 |
Hs.160953 Hs.711194 |
11 |
molecular_function mitochondrion apoptosis |
p53 signaling pathway |
229341_at |
0.240 |
4.825 |
2.758 |
1.449e-02 |
0.447 |
-2.870 |
TFCP2L1 |
transcription factor CP2-like 1 |
2 |
-121690635 |
AW195353 |
29842 |
2q14 |
Hs.156471 |
8 |
negative regulation of transcription from RNA polymerase II promoter cell morphogenesis epithelial cell maturation transcription factor activity transcription corepressor activity nucleus cytoplasm steroid biosynthetic process cytoplasm organization salivary gland development female pregnancy determination of adult lifespan membrane general transcriptional repressor activity regulation of transcription positive regulation of growth |
|
241221_at |
-0.282 |
4.792 |
-2.668 |
1.741e-02 |
0.471 |
-3.025 |
SEC14L3 |
SEC14-like 3 (S. cerevisiae) |
22 |
-29185216 |
BE644691 |
266629 |
22q12.2 |
Hs.505601 |
6 |
transporter activity intracellular transport lipid binding |
|
226616_s_at |
NDUFV3 |
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa |
21 |
43186446 |
NM_021075 |
4731 |
21q22.3 |
Hs.473937 |
16 |
mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane electron transport chain respiratory chain |
Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease |
210154_at |
0.562 |
6.228 |
2.613 |
1.941e-02 |
0.489 |
-3.117 |
ME2 |
malic enzyme 2, NAD(+)-dependent, mitochondrial |
18 |
46659432 |
M55905 |
4200 |
18q21 6p25-p24 |
Hs.233119 |
24 |
malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction |
Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide |
200984_s_at |
CD59 |
CD59 molecule, complement regulatory protein |
11 |
-33681131, -33681131, -33681131 |
X16447 |
966 |
11p13 |
Hs.278573 Hs.709466 Hs.710641 |
107 |
protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane |
Complement and coagulation cascades Hematopoietic cell lineage |
221530_s_at |
-0.877 |
9.452 |
-3.123 |
6.883e-03 |
0.370 |
-2.239 |
BHLHE41 |
basic helix-loop-helix family, member e41 |
12 |
-26164227 |
BE857425 |
79365 |
12p11.23-p12.1 |
Hs.177841 |
15 |
transcription factor activity nucleus regulation of transcription, DNA-dependent cell proliferation organ morphogenesis cell differentiation |
Circadian rhythm - mammal |
216167_at |
LRRN2 |
leucine rich repeat neuronal 2 |
1 |
-202852925, -202852925 |
AK024867 |
10446 |
1q32.1 |
Hs.26312 |
7 |
receptor activity protein binding cell adhesion signal transduction membrane integral to membrane |
|
230394_at |
TCP10L |
t-complex 10 (mouse)-like |
21 |
-32869022 |
AI336920 |
140290 |
21q22.11 |
Hs.42034 |
11 |
|
|
214270_s_at |
0.435 |
4.051 |
2.813 |
1.299e-02 |
0.432 |
-2.778 |
MAPRE3 |
microtubule-associated protein, RP/EB family, member 3 |
2 |
27047028 |
AI885178 |
22924 |
2p23.3-p23.1 |
Hs.515860 |
13 |
small GTPase regulator activity cytoplasm microtubule cell cycle mitosis microtubule binding midbody positive regulation of gene-specific transcription cell division |
|
210349_at |
-0.245 |
3.436 |
-2.278 |
3.760e-02 |
0.564 |
-3.669 |
CAMK4 |
calcium/calmodulin-dependent protein kinase IV |
5 |
110587980 |
L24959 |
814 |
5q21.3 |
Hs.591269 |
46 |
nucleotide binding calmodulin-dependent protein kinase activity calcium ion binding calmodulin binding ATP binding nucleus nucleolus cytoplasm protein amino acid phosphorylation signal transduction transferase activity |
Calcium signaling pathway Long-term potentiation Neurotrophin signaling pathway |
210335_at |
0.328 |
2.782 |
2.460 |
2.630e-02 |
0.521 |
-3.372 |
RASSF9 |
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 |
12 |
-84722461 |
AF056209 |
9182 |
12q21.31 |
Hs.527881 |
4 |
transporter activity protein binding endosome cytosol protein targeting signal transduction trans-Golgi network transport vesicle membrane endosome transport |
|
205926_at |
IL27RA |
interleukin 27 receptor, alpha |
19 |
14003261 |
NM_004843 |
9466 |
19p13.11 |
Hs.132781 |
12 |
positive regulation of T-helper 1 type immune response negative regulation of T-helper 2 type immune response transmembrane receptor activity protein binding integral to plasma membrane immune response cell surface receptor linked signal transduction membrane positive regulation of interferon-gamma production interleukin-27 receptor activity regulation of isotype switching to IgG isotypes defense response to Gram-positive bacterium |
|
205189_s_at |
FANCC |
Fanconi anemia, complementation group C |
9 |
-96901156 |
NM_000136 |
2176 |
9q22.3 |
Hs.494529 |
77 |
protein binding nucleus cytoplasm cytosol DNA repair protein complex assembly response to DNA damage stimulus |
|
215355_at |
-0.257 |
2.647 |
-2.361 |
3.198e-02 |
0.545 |
-3.535 |
POU2F3 |
POU class 2 homeobox 3 |
11 |
119616160 |
AI686582 |
25833 |
11q23.3 |
Hs.227115 |
13 |
transcription factor activity nucleus transcription factor complex epidermis development keratinocyte differentiation wound healing sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein dimerization activity |
|
218360_at |
0.458 |
6.059 |
3.739 |
1.933e-03 |
0.273 |
-1.158 |
RAB22A |
RAB22A, member RAS oncogene family |
20 |
56318176 |
NM_020673 |
57403 |
20q13.32 |
Hs.529044 |
14 |
nucleotide binding GTPase activity protein binding protein binding GTP binding early endosome plasma membrane endocytosis endosome organization small GTPase mediated signal transduction protein transport |
Endocytosis |
221499_s_at |
STX16 |
syntaxin 16 |
20 |
56659733, 56659733 |
AK026970 |
8675 |
20q13.32 |
Hs.307913 |
14 |
SNAP receptor activity cytoplasm microsome Golgi apparatus intracellular protein transport intra-Golgi vesicle-mediated transport membrane integral to membrane vesicle-mediated transport SNARE complex retrograde transport, endosome to Golgi |
SNARE interactions in vesicular transport |
215777_at |
-0.196 |
4.405 |
-2.134 |
4.950e-02 |
0.590 |
-3.895 |
IGLV4-60 |
immunoglobulin lambda variable 4-60 |
22 |
|
AW405975 |
28785 |
22q11.2 |
|
5 |
|
|
224714_at |
0.413 |
7.692 |
2.483 |
2.516e-02 |
0.514 |
-3.334 |
MKI67IP |
MKI67 (FHA domain) interacting nucleolar phosphoprotein |
2 |
-122200991 |
AL542544 |
84365 |
2q14.3 |
Hs.367842 |
8 |
nucleotide binding condensed nuclear chromosome condensed nuclear chromosome RNA binding RNA binding protein binding protein binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm cytoplasm protein complex assembly rRNA transcription rRNA metabolic process |
|
208723_at |
USP11 |
ubiquitin specific peptidase 11 |
X |
46977257 |
BC000350 |
8237 |
Xp11.23 |
Hs.171501 |
18 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity protein binding nucleus ubiquitin-dependent protein catabolic process peptidase activity |
|
209531_at |
0.283 |
7.331 |
2.130 |
4.991e-02 |
0.591 |
-3.902 |
GSTZ1 |
glutathione transferase zeta 1 |
14 |
76856982, 76857458 |
BC001453 |
2954 |
14q24.3 |
Hs.655292 |
31 |
glutathione transferase activity glutathione peroxidase activity protein binding cytoplasm mitochondrion cytosol L-phenylalanine catabolic process tyrosine catabolic process aromatic amino acid family metabolic process maleylacetoacetate isomerase activity maleylacetoacetate isomerase activity transferase activity isomerase activity |
Tyrosine metabolism Glutathione metabolism Styrene degradation Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways |
241512_at |
SPATC1 |
spermatogenesis and centriole associated 1 |
8 |
145158569 |
AI026805 |
375686 |
8q24.3 |
Hs.97726 |
3 |
cytoplasm centrosome |
|
212189_s_at |
COG4 |
component of oligomeric golgi complex 4 |
16 |
-69071972 |
AK022874 |
25839 |
16q22.1 |
Hs.208680 |
11 |
protein binding Golgi apparatus protein transport membrane Golgi transport complex |
|
220761_s_at |
0.323 |
6.337 |
2.437 |
2.755e-02 |
0.526 |
-3.410 |
TAOK3 |
TAO kinase 3 |
12 |
-117071988 |
NM_016281 |
51347 |
12q |
Hs.644420 |
10 |
nucleotide binding protein serine/threonine kinase activity protein kinase inhibitor activity ATP binding cytoplasm mitochondrion plasma membrane transferase activity negative regulation of JNK cascade positive regulation of JNK cascade protein amino acid autophosphorylation |
MAPK signaling pathway |
206571_s_at |
0.468 |
6.053 |
2.854 |
1.194e-02 |
0.426 |
-2.706 |
MAP4K4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
2 |
101680919 |
NM_004834 |
9448 |
2q11.2-q12 |
Hs.719073 |
22 |
nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cellular_component protein amino acid phosphorylation response to stress protein kinase cascade transferase activity |
MAPK signaling pathway |
204648_at |
NPR1 |
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) |
1 |
151917787 |
NM_000906 |
4881 |
1q21-q22 |
Hs.490330 |
50 |
nucleotide binding guanylate cyclase activity protein tyrosine kinase activity receptor activity ATP binding GTP binding integral to plasma membrane cGMP biosynthetic process protein amino acid phosphorylation cell surface receptor linked signal transduction intracellular signaling cascade regulation of blood pressure peptide receptor activity, G-protein coupled membrane negative regulation of angiogenesis diuresis natriuresis negative regulation of cell growth chloride ion binding regulation of vasodilation hormone binding regulation of vascular permeability |
Purine metabolism Vascular smooth muscle contraction |
227649_s_at |
SRGAP2 |
SLIT-ROBO Rho GTPase activating protein 2 |
1 |
204582822, 204582822 |
AU144000 |
23380 |
1q32.1 |
Hs.497575 |
7 |
GTPase activator activity intracellular signal transduction |
Axon guidance |
223255_at |
G2E3 |
G2/M-phase specific E3 ubiquitin ligase |
14 |
30098079 |
AA642341 |
55632 |
14q12 |
Hs.509008 Hs.605081 |
13 |
protein polyubiquitination blastocyst development ubiquitin-protein ligase activity protein binding intracellular nucleus nucleolus cytoplasm Golgi apparatus protein modification process multicellular organismal development zinc ion binding ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process negative regulation of apoptosis metal ion binding |
|
243645_at |
NFASC |
neurofascin homolog (chicken) |
1 |
203064404, 203064404, 203179976 |
AW102637 |
23114 |
1q32.1 |
Hs.13349 |
28 |
protein binding plasma membrane cell adhesion integral to membrane |
Cell adhesion molecules (CAMs) |
238885_at |
0.244 |
4.757 |
2.851 |
1.200e-02 |
0.426 |
-2.711 |
KIAA1549 |
KIAA1549 |
7 |
-138166666 |
AV704797 |
57670 |
7q34 |
Hs.605380 |
5 |
membrane integral to membrane |
|
203797_at |
VSNL1 |
visinin-like 1 |
2 |
17585287 |
AF039555 |
7447 |
2p24.3 |
Hs.444212 |
29 |
calcium ion binding |
|
213376_at |
0.379 |
6.831 |
2.442 |
2.728e-02 |
0.526 |
-3.402 |
ZBTB1 |
zinc finger and BTB domain containing 1 |
14 |
64041044, 64041044 |
AI656706 |
22890 |
14q23.3 |
Hs.655536 |
6 |
DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
203556_at |
ZHX2 |
zinc fingers and homeoboxes 2 |
8 |
123863081 |
NM_014943 |
22882 |
8q24.13 |
Hs.658443 Hs.719079 |
12 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding intracellular nucleus mRNA catabolic process zinc ion binding sequence-specific DNA binding metal ion binding |
|
201090_x_at |
0.585 |
10.198 |
2.734 |
1.522e-02 |
0.457 |
-2.912 |
TUBA1B |
tubulin, alpha 1b |
12 |
-47807832 |
NM_006082 |
10376 |
12q13.12 |
Hs.524390 Hs.719075 |
42 |
nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
213646_x_at |
0.621 |
10.324 |
2.839 |
1.231e-02 |
0.427 |
-2.732 |
TUBA1B |
tubulin, alpha 1b |
12 |
-47807832 |
BE300252 |
10376 |
12q13.12 |
Hs.524390 Hs.719075 |
42 |
nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
213225_at |
PPM1B |
protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform |
2 |
44249503, 44249503, 44249503 |
AJ271832 |
5495 |
2p21 |
Hs.416769 |
17 |
magnesium ion binding protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation protein serine/threonine phosphatase complex hydrolase activity manganese ion binding |
MAPK signaling pathway |
216470_x_at |
-0.239 |
4.000 |
-2.644 |
1.827e-02 |
0.480 |
-3.066 |
PRSS1 |
protease, serine, 1 (trypsin 1) |
7 |
142136892 |
AF009664 |
5644 |
7q32-qter 7q34 |
Hs.622865 Hs.654498 |
100 |
serine-type endopeptidase activity calcium ion binding protein binding extracellular region extracellular space proteolysis digestion peptidase activity |
Neuroactive ligand-receptor interaction |
202503_s_at |
0.761 |
3.502 |
2.401 |
2.956e-02 |
0.536 |
-3.469 |
KIAA0101 |
KIAA0101 |
15 |
-62444263 |
NM_014736 |
9768 |
15q22.31 |
Hs.81892 |
11 |
nucleus mitochondrion |
|
201832_s_at |
USO1 |
USO1 homolog, vesicle docking protein (yeast) |
4 |
76868852 |
NM_003715 |
8615 |
4q21.1 |
Hs.292689 |
34 |
Golgi membrane protein binding cytoplasm microsome Golgi apparatus cytosol intracellular protein transport protein transporter activity membrane vesicle-mediated transport vesicle fusion with Golgi apparatus perinuclear region of cytoplasm |
|
215767_at |
ZNF804A |
zinc finger protein 804A |
2 |
185171337 |
AF052145 |
91752 |
2q32.1 |
Hs.159528 |
8 |
intracellular zinc ion binding metal ion binding |
|
215509_s_at |
BUB1 |
budding uninhibited by benzimidazoles 1 homolog (yeast) |
2 |
-111111882 |
AL137654 |
699 |
2q14 |
Hs.469649 |
55 |
nucleotide binding condensed chromosome kinetochore condensed nuclear chromosome, centromeric region protein serine/threonine kinase activity ATP binding nucleus spindle pole body protein amino acid phosphorylation cell cycle mitosis mitotic cell cycle spindle assembly checkpoint cell proliferation transferase activity cell division |
Cell cycle |
224905_at |
0.463 |
6.667 |
3.030 |
8.339e-03 |
0.387 |
-2.402 |
WDR26 |
WD repeat domain 26 |
1 |
-222639467 |
AA482548 |
80232 |
1q42.11-q42.12 |
Hs.497873 |
8 |
cytoplasm |
|
233842_x_at |
C20orf43 |
chromosome 20 open reading frame 43 |
20 |
54477053 |
AK000586 |
51507 |
20q13.31 |
Hs.517134 |
10 |
molecular_function cellular_component biological_process |
|
225003_at |
0.326 |
8.568 |
2.518 |
2.347e-02 |
0.507 |
-3.276 |
TMEM205 |
transmembrane protein 205 |
19 |
-11314451 |
BF343862 |
374882 |
19p13.2 |
Hs.8036 |
2 |
membrane integral to membrane |
|
225993_at |
0.262 |
5.505 |
2.162 |
4.694e-02 |
0.583 |
-3.852 |
EARS2 |
glutamyl-tRNA synthetase 2, mitochondrial (putative) |
16 |
-23440834 |
AL520723 |
124454 |
16p12.2 |
Hs.620541 |
6 |
nucleotide binding RNA binding glutamate-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix glutamyl-tRNA aminoacylation ligase activity |
Porphyrin and chlorophyll metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways |
201829_at |
NET1 |
neuroepithelial cell transforming 1 |
10 |
5444517, 5478545 |
AW263232 |
10276 |
10p15 |
Hs.25155 |
19 |
regulation of cell growth guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity cellular_component intracellular nucleus cytoplasm intracellular signaling cascade regulation of Rho protein signal transduction |
|
219824_at |
-0.213 |
5.833 |
-2.237 |
4.066e-02 |
0.570 |
-3.734 |
SLC13A4 |
solute carrier family 13 (sodium/sulfate symporters), member 4 |
7 |
-135016526 |
NM_012450 |
26266 |
7q33 |
Hs.200022 Hs.490241 |
5 |
transporter activity integral to plasma membrane ion transport sodium ion transport sulfate transport symporter activity sodium:sulfate symporter activity membrane sodium ion binding |
|
1566108_at |
-0.242 |
3.203 |
-2.615 |
1.933e-02 |
0.489 |
-3.113 |
MYNN |
myoneurin |
3 |
170973546 |
AK056483 |
55892 |
3q26.2 |
Hs.507025 |
6 |
transcription factor activity protein binding intracellular nucleus transcription, DNA-dependent zinc ion binding regulation of transcription metal ion binding |
|
208977_x_at |
0.507 |
8.862 |
2.198 |
4.381e-02 |
0.578 |
-3.795 |
TUBB2C |
tubulin, beta 2C |
9 |
139255531 |
BC004188 |
10383 |
9q34 |
Hs.433615 |
25 |
nucleotide binding GTPase activity structural molecule activity GTP binding cytoskeleton microtubule cell motion microtubule-based movement natural killer cell mediated cytotoxicity MHC class I protein binding protein complex unfolded protein binding protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
211750_x_at |
0.599 |
9.757 |
2.576 |
2.090e-02 |
0.497 |
-3.179 |
TUBA1C |
tubulin, alpha 1c |
12 |
47945131 |
BC005946 |
84790 |
12q12-q14 |
Hs.719091 |
19 |
nucleotide binding GTPase activity structural molecule activity protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
227127_at |
TMEM110 |
transmembrane protein 110 |
3 |
-52848937 |
BF222855 |
375346 |
3p21.1 |
Hs.705605 |
2 |
molecular_function cellular_component biological_process membrane integral to membrane |
|
221023_s_at |
KCNH6 |
potassium voltage-gated channel, subfamily H (eag-related), member 6 |
17 |
58954426, 58954426 |
NM_030779 |
81033 |
17q23.3 |
Hs.591177 |
6 |
voltage-gated ion channel activity voltage-gated potassium channel activity regulation of transcription, DNA-dependent ion transport potassium ion transport signal transduction membrane integral to membrane potassium ion binding |
|
212222_at |
0.504 |
8.865 |
3.310 |
4.685e-03 |
0.336 |
-1.911 |
PSME4 |
proteasome (prosome, macropain) activator subunit 4 |
2 |
-53944707 |
AU143855 |
23198 |
2p16.2 |
Hs.413801 |
30 |
binding nucleus cytosol multicellular organismal development spermatogenesis nuclear speck cell differentiation protein complex |
Proteasome |
206882_at |
SLC1A6 |
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
19 |
-14921990 |
NM_005071 |
6511 |
19p13.12 |
Hs.515217 |
11 |
L-glutamate transmembrane transporter activity membrane fraction integral to plasma membrane transport dicarboxylic acid transport synaptic transmission anion transmembrane transporter activity L-aspartate transmembrane transporter activity symporter activity aspartate transport L-glutamate transport membrane sodium:dicarboxylate symporter activity regulation of membrane potential |
|
219748_at |
TREML2 |
triggering receptor expressed on myeloid cells-like 2 |
6 |
-41265529 |
NM_024807 |
79865 |
6p21.1 |
Hs.164797 |
6 |
receptor activity protein binding plasma membrane cell surface integral to membrane T cell activation |
|
218578_at |
CDC73 |
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) |
1 |
191357710 |
NM_024529 |
79577 |
1q25 |
Hs.378996 Hs.576497 |
59 |
protein binding nucleus transcription cell cycle histone monoubiquitination Cdc73/Paf1 complex histone H2B ubiquitination |
|
210809_s_at |
2.145 |
4.870 |
2.796 |
1.344e-02 |
0.437 |
-2.806 |
POSTN |
periostin, osteoblast specific factor |
13 |
-37034719 |
D13665 |
10631 |
13q13.3 |
Hs.136348 |
38 |
skeletal system development protein binding extracellular region proteinaceous extracellular matrix cell adhesion heparin binding |
|
201362_at |
0.635 |
6.719 |
2.935 |
1.012e-02 |
0.415 |
-2.566 |
IVNS1ABP |
influenza virus NS1A binding protein |
1 |
-183532144 |
AF205218 |
10625 |
1q25.1-q31.1 |
Hs.497183 |
9 |
protein binding nucleus nucleoplasm transcription factor complex spliceosomal complex cytoplasm cytoskeleton transcription from RNA polymerase III promoter RNA splicing response to virus interspecies interaction between organisms |
|
219958_at |
C20orf46 |
chromosome 20 open reading frame 46 |
20 |
-1109214 |
NM_018354 |
55321 |
20p13 |
Hs.516834 |
4 |
protein binding membrane integral to membrane |
|
213996_at |
YPEL1 |
yippee-like 1 (Drosophila) |
22 |
-20381825 |
NM_013313 |
29799 |
22q11.2 |
Hs.517436 |
7 |
nucleus |
|
222568_at |
0.360 |
6.088 |
3.301 |
4.776e-03 |
0.338 |
-1.928 |
UGGT1 |
UDP-glucose glycoprotein glucosyltransferase 1 |
2 |
128565223, 128565251 |
AI672492 |
56886 |
2q14.3 |
Hs.598715 Hs.719174 |
10 |
UDP-glucose:glycoprotein glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum lumen ER-Golgi intermediate compartment protein amino acid glycosylation transferase activity, transferring glycosyl groups unfolded protein binding 'de novo' posttranslational protein folding |
|
226926_at |
DMKN |
dermokine |
19 |
-40686045, -40679961, -40679961, -40679961 |
AA706316 |
93099 |
19q13.12 |
Hs.417795 |
7 |
extracellular region extracellular space |
|
200811_at |
0.422 |
9.328 |
2.492 |
2.473e-02 |
0.513 |
-3.320 |
CIRBP |
cold inducible RNA binding protein |
19 |
1220266, 1220266 |
NM_001280 |
1153 |
19p13.3 |
Hs.634522 Hs.664127 |
17 |
nucleotide binding RNA binding protein binding nucleus nucleoplasm response to cold |
|
232235_at |
0.625 |
2.882 |
2.815 |
1.291e-02 |
0.432 |
-2.773 |
DSEL |
dermatan sulfate epimerase-like |
18 |
-63324798 |
AK021539 |
92126 |
18q22.1 |
Hs.124673 |
6 |
membrane integral to membrane |
|
209251_x_at |
0.586 |
9.843 |
2.532 |
2.283e-02 |
0.503 |
-3.253 |
TUBA1C |
tubulin, alpha 1c |
12 |
47945131 |
BC004949 |
84790 |
12q12-q14 |
Hs.719091 |
19 |
nucleotide binding GTPase activity structural molecule activity protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
219594_at |
NINJ2 |
ninjurin 2 |
12 |
-543722 |
NM_016533 |
4815 |
12p13 |
Hs.656450 |
5 |
protein binding integral to plasma membrane cell adhesion neuron adhesion nervous system development membrane tissue regeneration |
|
218637_at |
IMPACT |
Impact homolog (mouse) |
18 |
20260606 |
NM_018439 |
55364 |
18q11.2-q12.1 |
Hs.515317 |
6 |
molecular_function cellular_component regulation of translation biological_process |
|
232185_at |
C20orf132 |
chromosome 20 open reading frame 132 |
20 |
-35190637, -35163042 |
AL136172 |
140699 |
20q11.22 |
Hs.349125 |
9 |
|
|
209231_s_at |
DCTN5 |
dynactin 5 (p25) |
16 |
23560307 |
AI038068 |
84516 |
16p12.2 |
Hs.435941 |
7 |
cytoplasm cytoskeleton transferase activity |
|
225369_at |
ESAM |
endothelial cell adhesion molecule |
11 |
-124128228 |
AL573851 |
90952 |
11q24.2 |
Hs.173840 |
11 |
protein binding plasma membrane adherens junction tight junction homophilic cell adhesion integral to membrane cell junction |
Cell adhesion molecules (CAMs) Leukocyte transendothelial migration |
209834_at |
0.315 |
5.962 |
2.271 |
3.807e-02 |
0.565 |
-3.679 |
CHST3 |
carbohydrate (chondroitin 6) sulfotransferase 3 |
10 |
73394125 |
AB017915 |
9469 |
10q22.1 |
Hs.158304 |
15 |
Golgi membrane Golgi apparatus carbohydrate metabolic process sulfur metabolic process sulfotransferase activity chondroitin 6-sulfotransferase activity membrane integral to membrane transferase activity chondroitin sulfate biosynthetic process |
Chondroitin sulfate biosynthesis |
203775_at |
SLC25A13 |
solute carrier family 25, member 13 (citrin) |
7 |
-95587468, -95587467 |
NM_014251 |
10165 |
7q21.3 |
Hs.489190 |
31 |
transporter activity L-glutamate transmembrane transporter activity binding calcium ion binding mitochondrion mitochondrial inner membrane integral to plasma membrane ATP biosynthetic process transport L-aspartate transmembrane transporter activity aspartate transport L-glutamate transport membrane malate-aspartate shuttle cellular respiration response to calcium ion |
|
226336_at |
PPIA |
peptidylprolyl isomerase A (cyclophilin A) |
7 |
44802765 |
T62044 |
5478 |
7p13 |
Hs.356331 Hs.598115 |
164 |
peptidyl-prolyl cis-trans isomerase activity extracellular region nucleus cytoplasm cytosol cytosol protein folding isomerase activity provirus integration initiation of viral infection peptide binding interspecies interaction between organisms regulation of viral genome replication regulation of viral genome replication virion binding unfolded protein binding |
|
204218_at |
0.220 |
7.419 |
2.140 |
4.891e-02 |
0.590 |
-3.886 |
C11orf51 |
chromosome 11 open reading frame 51 |
11 |
-71498280 |
NM_014042 |
25906 |
11q13.4 |
Hs.38044 |
7 |
intracellular |
|
203404_at |
0.320 |
6.255 |
2.186 |
4.489e-02 |
0.581 |
-3.815 |
ARMCX2 |
armadillo repeat containing, X-linked 2 |
X |
-100796925 |
NM_014782 |
9823 |
Xq21.33-q22.2 |
Hs.48924 |
7 |
binding membrane integral to membrane |
|
210592_s_at |
0.515 |
7.644 |
3.312 |
4.664e-03 |
0.336 |
-1.907 |
SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
X |
23711195 |
M55580 |
6303 |
Xp22.1 |
Hs.28491 |
46 |
diamine N-acetyltransferase activity protein binding intracellular cytoplasm metabolic process acyltransferase activity transferase activity |
Arginine and proline metabolism Metabolic pathways |
227118_s_at |
-0.285 |
4.432 |
-2.822 |
1.274e-02 |
0.431 |
-2.762 |
MRPS26 |
mitochondrial ribosomal protein S26 |
20 |
2974674 |
AA594308 |
64949 |
20p13 |
Hs.18946 |
10 |
mitochondrion mitochondrial small ribosomal subunit ribosome DNA damage response, detection of DNA damage peptide biosynthetic process |
|
214440_at |
NAT1 |
N-acetyltransferase 1 (arylamine N-acetyltransferase) |
8 |
18072250, 18111897, 18123456 |
NM_000662 |
9 |
8p23.1-p21.3 |
Hs.591847 |
163 |
arylamine N-acetyltransferase activity cytoplasm cytosol metabolic process acetyltransferase activity transferase activity |
Caffeine metabolism Drug metabolism - other enzymes Metabolic pathways |
208267_at |
TRPV5 |
transient receptor potential cation channel, subfamily V, member 5 |
7 |
-142315769 |
NM_019841 |
56302 |
7q35 |
Hs.283369 |
34 |
ion channel activity calcium channel activity calcium ion binding protein binding plasma membrane integral to plasma membrane ion transport calcium ion transport calcium ion transport apical plasma membrane protein tetramerization |
|
201305_x_at |
0.596 |
8.368 |
3.247 |
5.339e-03 |
0.351 |
-2.023 |
ANP32B |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
9 |
99785309 |
AV712577 |
10541 |
9q22.32 |
Hs.715547 |
16 |
protein binding nucleus |
|
213086_s_at |
0.433 |
8.418 |
2.295 |
3.638e-02 |
0.559 |
-3.642 |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
BF341845 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
229863_s_at |
0.235 |
6.248 |
2.263 |
3.869e-02 |
0.567 |
-3.693 |
C3orf75 |
chromosome 3 open reading frame 75 |
3 |
-47512133 |
BE503382 |
54859 |
3p21.31 |
Hs.311100 |
4 |
molecular_function cellular_component biological_process |
|
235760_at |
0.381 |
5.317 |
2.378 |
3.092e-02 |
0.542 |
-3.507 |
NSD1 |
nuclear receptor binding SET domain protein 1 |
5 |
176492685, 176493438 |
AI421972 |
64324 |
5q35.2-q35.3 |
Hs.106861 |
36 |
negative regulation of transcription from RNA polymerase II promoter chromatin binding transcription corepressor activity protein binding nucleus methyltransferase activity zinc ion binding chromatin modification histone methylation transferase activity ligand-dependent nuclear receptor binding estrogen receptor binding histone methyltransferase activity (H4-K20 specific) regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding |
Lysine degradation |
201964_at |
SETX |
senataxin |
9 |
-134126647 |
N64643 |
23064 |
9q34.13 |
Hs.460317 |
24 |
nucleotide binding DNA binding DNA helicase activity ATP binding nucleus nucleoplasm nucleolus cytoplasm double-strand break repair RNA processing response to DNA damage stimulus cell death hydrolase activity |
|
213027_at |
0.334 |
6.765 |
2.386 |
3.046e-02 |
0.541 |
-3.494 |
TROVE2 |
TROVE domain family, member 2 |
1 |
191295375, 191295579, 191295579 |
AU146655 |
6738 |
1q31 |
Hs.288178 |
24 |
RNA binding protein binding cytoplasm transcription from RNA polymerase III promoter ribonucleoprotein complex |
Systemic lupus erythematosus |
1554015_a_at |
0.387 |
4.832 |
2.705 |
1.614e-02 |
0.461 |
-2.962 |
CHD2 |
chromodomain helicase DNA binding protein 2 |
15 |
91244554, 91244554 |
BC007347 |
1106 |
15q26 |
Hs.220864 |
9 |
nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter hydrolase activity |
|
214613_at |
GPR3 |
G protein-coupled receptor 3 |
1 |
27591738 |
AW024085 |
2827 |
1p36.1-p35 |
Hs.66542 |
10 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway regulation of meiosis |
|
1556907_at |
ZNF474 |
zinc finger protein 474 |
5 |
121493113 |
BM979960 |
133923 |
5q23.2 |
Hs.646680 |
3 |
intracellular zinc ion binding metal ion binding |
|
237639_at |
TMEM207 |
transmembrane protein 207 |
3 |
-191629139 |
AI913600 |
131920 |
3q28 |
Hs.335321 |
2 |
membrane integral to membrane |
|
207702_s_at |
0.550 |
4.869 |
3.828 |
1.609e-03 |
0.259 |
-1.003 |
MAGI2 |
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
7 |
-77484309 |
NM_012301 |
9863 |
7q21 |
Hs.603842 |
22 |
protein binding plasma membrane synaptosome phosphatase binding cell junction synapse |
Tight junction |
1554386_at |
CST9 |
cystatin 9 (testatin) |
20 |
-23531048 |
AF494536 |
128822 |
20p11.21 |
Hs.698020 |
3 |
cysteine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity |
|
201635_s_at |
FXR1 |
fragile X mental retardation, autosomal homolog 1 |
3 |
182113145 |
AI990766 |
8087 |
3q28 |
Hs.478407 |
30 |
RNA binding nucleolus cytoplasm polysome apoptosis multicellular organismal development muscle organ development cell differentiation |
|
213476_x_at |
TUBB3 |
tubulin, beta 3 |
16 |
88517245 |
AL565749 |
10381 |
16q24.3 |
Hs.511743 |
41 |
nucleotide binding GTPase activity structural molecule activity GTP binding intracellular microtubule microtubule-based movement mitosis neuron differentiation axon protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
223928_s_at |
GUCA1C |
guanylate cyclase activator 1C |
3 |
-110109331 |
AF110002 |
9626 |
3q13.1 |
Hs.233363 |
4 |
calcium ion binding signal transduction visual perception calcium sensitive guanylate cyclase activator activity |
Olfactory transduction |
225765_at |
0.345 |
6.870 |
3.309 |
4.691e-03 |
0.336 |
-1.912 |
TNPO1 |
transportin 1 |
5 |
72148173, 72179685 |
AA527296 |
3842 |
5q13.2 |
Hs.482497 |
58 |
protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
235106_at |
-0.321 |
3.272 |
-2.249 |
3.976e-02 |
0.568 |
-3.715 |
MAML2 |
mastermind-like 2 (Drosophila) |
11 |
-95351087 |
AW847318 |
84441 |
11q21 |
Hs.428214 |
17 |
transcription coactivator activity nucleus Notch signaling pathway nuclear speck regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
Notch signaling pathway |
239265_at |
0.532 |
4.832 |
2.547 |
2.216e-02 |
0.499 |
-3.228 |
TMEM20 |
transmembrane protein 20 |
10 |
95643719 |
R56424 |
159371 |
10q23.33 |
Hs.632085 |
4 |
membrane integral to membrane |
|
204587_at |
SLC25A14 |
solute carrier family 25 (mitochondrial carrier, brain), member 14 |
X |
129301727 |
NM_003951 |
9016 |
Xq24 |
Hs.194686 |
13 |
binding mitochondrion mitochondrial inner membrane integral to plasma membrane transport mitochondrial transport aerobic respiration membrane |
|
227557_at |
SCARF2 |
scavenger receptor class F, member 2 |
22 |
-19108874 |
AI127800 |
91179 |
22q11.21 |
Hs.474251 |
4 |
receptor activity scavenger receptor activity protein binding cell adhesion heterophilic cell adhesion membrane integral to membrane |
|
205324_s_at |
FTSJ1 |
FtsJ homolog 1 (E. coli) |
X |
48219492, 48221323 |
NM_012280 |
24140 |
Xp11.23 |
Hs.23170 |
15 |
nucleic acid binding rRNA processing methyltransferase activity transferase activity rRNA methylation methylation |
|
1563947_a_at |
ERC1 |
ELKS/RAB6-interacting/CAST family member 1 |
12 |
970664 |
AK097177 |
23085 |
12p13.3 |
Hs.655744 Hs.658200 |
19 |
protein binding cytoplasm Golgi apparatus regulation of transcription, DNA-dependent I-kappaB phosphorylation multicellular organismal development IkappaB kinase complex protein transport Rab GTPase binding retrograde transport, endosome to Golgi presynaptic membrane leucine zipper domain binding positive regulation of anti-apoptosis positive regulation of NF-kappaB transcription factor activity |
|
218311_at |
MAP4K3 |
mitogen-activated protein kinase kinase kinase kinase 3 |
2 |
-39329925 |
NM_003618 |
8491 |
2p22.1 |
Hs.655750 |
7 |
nucleotide binding protein serine/threonine kinase activity small GTPase regulator activity protein binding ATP binding protein amino acid phosphorylation response to stress protein kinase cascade JNK cascade transferase activity |
MAPK signaling pathway |
227684_at |
S1PR2 |
sphingosine-1-phosphate receptor 2 |
19 |
-10193108 |
AI032786 |
9294 |
19p13.2 |
Hs.655405 |
25 |
activation of MAPK activity lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway behavior positive regulation of cell proliferation lipid binding integral to membrane |
Neuroactive ligand-receptor interaction |
230718_at |
HSF5 |
heat shock transcription factor family member 5 |
17 |
-53852527 |
AL137385 |
124535 |
17q22 |
Hs.380061 |
1 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
204357_s_at |
0.392 |
6.282 |
4.225 |
7.136e-04 |
0.211 |
-0.316 |
LIMK1 |
LIM domain kinase 1 |
7 |
73136091 |
NM_002314 |
3984 |
7q11.23 |
Hs.647035 |
54 |
nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm focal adhesion protein amino acid phosphorylation signal transduction Rho protein signal transduction nervous system development zinc ion binding transferase activity actin cytoskeleton organization positive regulation of axon extension metal ion binding protein heterodimerization activity |
Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
205641_s_at |
TRADD |
TNFRSF1A-associated via death domain |
16 |
-65745589 |
NM_003789 |
8717 |
16q22 |
Hs.460996 |
68 |
signal transducer activity cytoplasm cytosol cytoskeleton induction of apoptosis signal transduction activation of pro-apoptotic gene products intermediate filament binding kinase binding tumor necrosis factor-mediated signaling pathway identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade receptor complex positive regulation of hair follicle development molecular adaptor activity death domain binding |
Apoptosis RIG-I-like receptor signaling pathway Adipocytokine signaling pathway |
226300_at |
0.377 |
6.938 |
2.919 |
1.046e-02 |
0.418 |
-2.595 |
MED19 |
mediator complex subunit 19 |
11 |
-57227762 |
BF109807 |
219541 |
11q12.1 |
Hs.43619 |
9 |
protein binding nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity regulation of transcription |
|
234485_at |
-0.340 |
4.785 |
-2.527 |
2.307e-02 |
0.505 |
-3.262 |
LOC340947 |
similar to eukaryotic translation initiation factor 3 subunit 6 interacting protein |
10 |
|
AL117339 |
340947 |
10p11.1 |
Hs.164084 |
|
|
|
228345_at |
CHIC1 |
cysteine-rich hydrophobic domain 1 |
X |
72699708 |
AI745136 |
53344 |
Xq13-q21 |
Hs.496323 |
5 |
plasma membrane cytoplasmic vesicle |
|
244682_at |
-0.278 |
2.545 |
-2.951 |
9.806e-03 |
0.409 |
-2.539 |
CAMSAP1 |
calmodulin regulated spectrin-associated protein 1 |
9 |
-137840153 |
H11471 |
157922 |
9q34.3 |
Hs.522493 |
2 |
|
|
227416_s_at |
ZCRB1 |
zinc finger CCHC-type and RNA binding motif 1 |
12 |
-40992154 |
BE265803 |
85437 |
12q12 |
Hs.496279 |
5 |
nucleotide binding RNA binding nucleus nucleoplasm U12-type spliceosomal complex mRNA processing zinc ion binding RNA splicing metal ion binding |
|
225212_at |
-1.093 |
7.631 |
-2.581 |
2.068e-02 |
0.497 |
-3.170 |
SLC25A25 |
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
9 |
129870299, 129893948, 129900637, 129900656 |
BC005163 |
114789 |
9q34.11 |
Hs.5476 |
6 |
binding calcium ion binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
219042_at |
LZTS1 |
leucine zipper, putative tumor suppressor 1 |
8 |
-20147956 |
NM_021020 |
11178 |
8p22 |
Hs.521432 |
11 |
transcription factor activity protein binding nucleus cytoplasm Golgi apparatus plasma membrane transcription regulation of transcription, DNA-dependent cell cycle postsynaptic density cell junction cell projection dendritic spine synapse postsynaptic membrane |
|
214334_x_at |
DAZAP2 |
DAZ associated protein 2 |
12 |
49918774, 49918774 |
N34846 |
9802 |
12q12 |
Hs.369761 |
15 |
protein binding WW domain binding |
|
228865_at |
C1orf116 |
chromosome 1 open reading frame 116 |
1 |
-205258488 |
AA622392 |
79098 |
1q32.1-q32.2 |
Hs.32417 |
6 |
receptor activity cytoplasm |
|
225229_at |
0.429 |
7.612 |
2.188 |
4.467e-02 |
0.580 |
-3.811 |
AFF4 |
AF4/FMR2 family, member 4 |
5 |
-132238969 |
AL044396 |
27125 |
5q31 |
Hs.519313 Hs.664840 |
10 |
transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription |
|
208752_x_at |
0.351 |
9.727 |
2.194 |
4.413e-02 |
0.579 |
-3.801 |
NAP1L1 |
nucleosome assembly protein 1-like 1 |
12 |
-74724938 |
AI888672 |
4673 |
12q21.2 |
Hs.524599 Hs.695185 |
17 |
protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome |
|
242931_at |
LONRF3 |
LON peptidase N-terminal domain and ring finger 3 |
X |
117992740 |
AI218358 |
79836 |
Xq24 |
Hs.144266 |
6 |
ATP-dependent peptidase activity protein binding proteolysis zinc ion binding metal ion binding |
|
203244_at |
PEX5 |
peroxisomal biogenesis factor 5 |
12 |
7233025, 7233548, 7234224 |
NM_000319 |
5830 |
12p13.31 |
Hs.567327 |
45 |
protein binding cytoplasm peroxisome protein transport membrane |
|
206444_at |
PDE1B |
phosphodiesterase 1B, calmodulin-dependent |
12 |
53229670 |
NM_000924 |
5153 |
12q13 |
Hs.530871 |
11 |
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding cytoplasm apoptosis signal transduction locomotory behavior visual learning hydrolase activity |
Purine metabolism Calcium signaling pathway |
206168_at |
-0.179 |
4.861 |
-2.426 |
2.812e-02 |
0.529 |
-3.428 |
ZC3H7B |
zinc finger CCCH-type containing 7B |
22 |
40027512 |
NM_025013 |
23264 |
22q13.2 |
Hs.592188 |
12 |
nucleic acid binding protein binding intracellular nucleus zinc ion binding interspecies interaction between organisms metal ion binding |
|
1553425_at |
-0.267 |
4.901 |
-2.852 |
1.199e-02 |
0.426 |
-2.710 |
WDR65 |
WD repeat domain 65 |
1 |
43410612 |
NM_152498 |
149465 |
1p34.2 |
Hs.647644 |
6 |
membrane integral to membrane |
|
224856_at |
1.283 |
8.312 |
3.432 |
3.644e-03 |
0.314 |
-1.697 |
FKBP5 |
FK506 binding protein 5 |
6 |
-35656311, -35649339, -35649339, -35649339 |
W86302 |
2289 |
6p21.3-p21.2 |
Hs.407190 |
50 |
peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus cytoplasm protein folding isomerase activity heat shock protein binding |
|
203003_at |
-0.301 |
6.833 |
-2.437 |
2.755e-02 |
0.526 |
-3.411 |
MEF2D |
myocyte enhancer factor 2D |
1 |
-154700142 |
AL530331 |
4209 |
1q12-q23 |
Hs.314327 |
35 |
transcription factor activity nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding |
|
202646_s_at |
CSDE1 |
cold shock domain containing E1, RNA-binding |
1 |
-115061060, -115061060, -115061059 |
AA167775 |
7812 |
1p22 |
Hs.69855 |
25 |
DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development |
|
214705_at |
INADL |
InaD-like (Drosophila) |
1 |
61980736 |
AJ001306 |
10207 |
1p31.3 |
Hs.478125 |
24 |
protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction |
Tight junction |
59644_at |
0.353 |
3.638 |
2.404 |
2.942e-02 |
0.536 |
-3.465 |
BMP2K |
BMP2 inducible kinase |
4 |
79916555, 79916555 |
AI735391 |
55589 |
4q21.21 |
Hs.146551 |
11 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation transferase activity |
|
202733_at |
0.540 |
6.211 |
3.371 |
4.129e-03 |
0.323 |
-1.804 |
P4HA2 |
prolyl 4-hydroxylase, alpha polypeptide II |
5 |
-131556204, -131556202, -131556202 |
NM_004199 |
8974 |
5q31 |
Hs.519568 |
14 |
procollagen-proline 4-dioxygenase activity iron ion binding protein binding endoplasmic reticulum endoplasmic reticulum lumen electron carrier activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen peptidyl-proline hydroxylation to 4-hydroxy-L-proline L-ascorbic acid binding metal ion binding oxidation reduction |
Arginine and proline metabolism Metabolic pathways |
220090_at |
-0.249 |
5.486 |
-2.205 |
4.322e-02 |
0.577 |
-3.784 |
CRNN |
cornulin |
1 |
-150648342 |
NM_016190 |
49860 |
1q21 |
Hs.242057 |
12 |
calcium ion binding cytoplasm response to unfolded protein metabolic process response to heat membrane membrane cell-cell adhesion |
|
223018_at |
0.228 |
6.731 |
2.566 |
2.132e-02 |
0.497 |
-3.196 |
NOB1 |
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) |
16 |
-68333274 |
BC000050 |
28987 |
16q22.3 |
Hs.271695 Hs.606475 |
8 |
protein binding nucleus zinc ion binding metal ion binding |
|
225528_at |
0.244 |
7.653 |
2.186 |
4.484e-02 |
0.581 |
-3.814 |
IPO8 |
importin 8 |
12 |
-30673188 |
AU149465 |
10526 |
12p11.21 |
Hs.505136 |
9 |
protein import into nucleus, docking protein binding nucleus nuclear pore cytoplasm intracellular protein transport signal transduction Ran GTPase binding protein transporter activity |
|
205155_s_at |
SPTBN2 |
spectrin, beta, non-erythrocytic 2 |
11 |
-66209296 |
NM_006946 |
6712 |
11q13 |
Hs.26915 |
18 |
actin binding structural constituent of cytoskeleton cytoplasm cytoskeleton cell cortex spectrin cell death vesicle-mediated transport actin filament capping |
|
235014_at |
0.511 |
7.048 |
3.523 |
3.020e-03 |
0.300 |
-1.538 |
LOC147727 |
hypothetical LOC147727 |
19 |
-10623538 |
BF345728 |
147727 |
19p13.2 |
Hs.631616 |
2 |
|
|
224779_s_at |
FAM96A |
family with sequence similarity 96, member A |
15 |
-62151813 |
AI193090 |
84191 |
15q22.31 |
Hs.439548 |
6 |
molecular_function cellular_component biological_process |
|
212116_at |
0.429 |
5.761 |
3.790 |
1.739e-03 |
0.267 |
-1.069 |
TRIM27 |
tripartite motif-containing 27 |
6 |
-28978757, -330309, -128126 |
NM_006510 |
5987 |
6p22 |
Hs.440382 |
27 |
negative regulation of transcription from RNA polymerase II promoter DNA binding transmembrane receptor protein tyrosine kinase activity protein binding intracellular membrane fraction nucleus nucleoplasm cytoplasm integral to plasma membrane spermatogenesis zinc ion binding cell proliferation nuclear membrane regulation of transcription negative regulation of gene expression, epigenetic metal ion binding protein trimerization |
|
229772_at |
-0.252 |
5.237 |
-2.372 |
3.129e-02 |
0.543 |
-3.517 |
DEFB123 |
defensin, beta 123 |
20 |
29492071 |
AA789269 |
245936 |
20q11.1 |
Hs.122509 |
4 |
extracellular region defense response to bacterium |
|
214207_s_at |
CARD10 |
caspase recruitment domain family, member 10 |
22 |
-36216345 |
AW024347 |
29775 |
22q13.1 |
Hs.57973 |
15 |
protein binding intracellular cytoplasm protein complex assembly activation of NF-kappaB-inducing kinase activity receptor signaling complex scaffold activity CBM complex regulation of apoptosis |
|
1569033_at |
-0.233 |
4.240 |
-2.484 |
2.509e-02 |
0.513 |
-3.332 |
IGF2BP3 |
insulin-like growth factor 2 mRNA binding protein 3 |
7 |
-23316352 |
BC019258 |
10643 |
7p11 |
Hs.700696 |
37 |
nucleotide binding RNA binding nucleus cytoplasm anatomical structure morphogenesis negative regulation of translation regulation of cytokine biosynthetic process translation regulator activity mRNA 5'-UTR binding |
|
209914_s_at |
NRXN1 |
neurexin 1 |
2 |
-49999147, -49999147 |
AW149405 |
9378 |
2p16.3 |
Hs.637685 |
36 |
receptor activity calcium ion binding protein binding protein binding integral to plasma membrane cell adhesion axon guidance membrane integral to membrane |
Cell adhesion molecules (CAMs) |
206567_s_at |
PHF20 |
PHD finger protein 20 |
20 |
33823336 |
NM_016436 |
51230 |
20q11.22-q11.23 |
Hs.517044 |
11 |
DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
211058_x_at |
0.575 |
10.584 |
2.715 |
1.581e-02 |
0.459 |
-2.944 |
TUBA1B |
tubulin, alpha 1b |
12 |
-47807832 |
BC006379 |
10376 |
12q13.12 |
Hs.524390 Hs.719075 |
42 |
nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
226285_at |
CAPRIN1 |
cell cycle associated protein 1 |
11 |
34029805, 34029805 |
AI808634 |
4076 |
11p13 |
Hs.471818 |
10 |
protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection |
|
206723_s_at |
LPAR2 |
lysophosphatidic acid receptor 2 |
19 |
-19595465 |
AF011466 |
9170 |
19p12 |
Hs.122575 |
34 |
activation of MAPK activity lysosphingolipid and lysophosphatidic acid receptor activity receptor activity G-protein coupled receptor activity protein binding plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway activation of phospholipase C activity elevation of cytosolic calcium ion concentration lipid binding PDZ domain binding LIM domain binding positive regulation of Rho protein signal transduction positive regulation of MAPKKK cascade |
Neuroactive ligand-receptor interaction |
218210_at |
FN3KRP |
fructosamine 3 kinase related protein |
17 |
78267870 |
NM_024619 |
79672 |
17q25.3 |
Hs.31431 |
12 |
kinase activity transferase activity |
|
211125_x_at |
GRIN1 |
glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
9 |
139153429 |
AF015730 |
2902 |
9q34.3 |
Hs.558334 |
119 |
magnesium ion binding receptor activity N-methyl-D-aspartate selective glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity calcium channel activity calcium ion binding calmodulin binding plasma membrane integral to plasma membrane cation transport synaptic transmission synaptic vesicle visual learning postsynaptic density glycine binding glycine binding glutamate binding N-methyl-D-aspartate selective glutamate receptor complex synaptosome cell junction dendrite ionotropic glutamate receptor signaling pathway glutamate receptor binding regulation of membrane potential synapse postsynaptic membrane response to ethanol positive regulation of transcription from RNA polymerase II promoter calcium ion homeostasis regulation of excitatory postsynaptic membrane potential |
Calcium signaling pathway Neuroactive ligand-receptor interaction Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Huntington's disease |
1562403_a_at |
SLC8A3 |
solute carrier family 8 (sodium/calcium exchanger), member 3 |
14 |
-69580686, -69580686, -69580686 |
AK096553 |
6547 |
14q24.1 |
Hs.337696 |
16 |
calcium:sodium antiporter activity calcium ion binding calmodulin binding ion transport sodium ion transport calcium ion transport cell communication antiporter activity membrane integral to membrane sodium ion binding |
Calcium signaling pathway |
227366_at |
RILP |
Rab interacting lysosomal protein |
17 |
-1496194 |
AI084782 |
83547 |
17p13.3 |
Hs.534497 |
20 |
lysosomal membrane protein transport membrane Rab GTPase binding phagocytic vesicle membrane cytoplasmic vesicle late endosome membrane |
|
225073_at |
PPHLN1 |
periphilin 1 |
12 |
41006213, 41006213, 41006213, 41006213 |
NM_016488 |
51535 |
12q12 |
Hs.444157 |
13 |
nucleus cytoplasm keratinization |
|
219341_at |
0.496 |
5.041 |
3.814 |
1.656e-03 |
0.263 |
-1.027 |
CLN8 |
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
8 |
1699276 |
NM_018941 |
2055 |
8p23 |
Hs.127675 |
15 |
age-dependent response to oxidative stress endoplasmic reticulum ER-Golgi intermediate compartment phospholipid metabolic process lipid transport mitochondrial membrane organization lysosome organization nervous system development adult walking behavior cholesterol metabolic process associative learning regulation of cell size lipid biosynthetic process membrane integral to membrane spinal cord motor neuron differentiation social behavior negative regulation of apoptosis cellular protein catabolic process cellular macromolecule catabolic process photoreceptor cell maintenance negative regulation of proteolysis ceramide biosynthetic process musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity glutamate uptake during transmission of nerve impulse retina development in camera-type eye neurofilament cytoskeleton organization |
|
205270_s_at |
LCP2 |
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
5 |
-169607665 |
NM_005565 |
3937 |
5q33.1-qter |
Hs.304475 |
72 |
protein binding cytoplasm cytosol immune response transmembrane receptor protein tyrosine kinase signaling pathway mast cell activation cytokine secretion |
Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway |
212280_x_at |
0.254 |
6.641 |
2.285 |
3.708e-02 |
0.562 |
-3.657 |
ATG4B |
ATG4 autophagy related 4 homolog B (S. cerevisiae) |
2 |
242225699, 54821 |
AA532726 |
23192 |
2q37.3 |
Hs.283610 |
19 |
protein binding cytoplasm microtubule associated complex proteolysis autophagy peptidase activity cysteine-type peptidase activity protein transport modification-dependent protein catabolic process |
Regulation of autophagy |
220793_at |
SAGE1 |
sarcoma antigen 1 |
X |
134803450 |
NM_018666 |
55511 |
Xq26 |
Hs.195292 |
4 |
|
|
232464_at |
TRIMP1 |
tripartite motif-containing pseudogene 1 |
11 |
5620987 |
AF230412 |
117852 |
11p15 |
Hs.709401 |
1 |
|
|
212367_at |
FEM1B |
fem-1 homolog b (C. elegans) |
15 |
66357194 |
AI799061 |
10116 |
15q22 |
Hs.362733 |
9 |
ubiquitin-protein ligase activity death receptor binding death receptor binding cellular_component cytoplasm induction of apoptosis modification-dependent protein catabolic process regulation of apoptosis regulation of ubiquitin-protein ligase activity |
|
1556262_at |
-0.384 |
5.895 |
-3.377 |
4.078e-03 |
0.323 |
-1.793 |
PWRN1 |
Prader-Willi region non-protein coding RNA 1 |
15 |
22354396 |
AK058147 |
791114 |
15q11.2 |
Hs.456065 |
2 |
|
|
202558_s_at |
0.375 |
4.897 |
2.863 |
1.171e-02 |
0.426 |
-2.690 |
HSPA13 |
heat shock protein 70kDa family, member 13 |
21 |
-14665307 |
NM_006948 |
6782 |
21q11 21q11.1 |
Hs.352341 |
16 |
nucleotide binding ATP binding endoplasmic reticulum microsome |
|
208753_s_at |
NAP1L1 |
nucleosome assembly protein 1-like 1 |
12 |
-74724938 |
BC002387 |
4673 |
12q21.2 |
Hs.524599 Hs.695185 |
17 |
protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome |
|
1558186_s_at |
0.382 |
2.952 |
3.432 |
3.645e-03 |
0.314 |
-1.698 |
CLLU1 |
chronic lymphocytic leukemia up-regulated 1 |
12 |
91339437, 91341865 |
BC014496 |
574028 |
12q22 |
Hs.339918 |
5 |
|
|
218534_s_at |
AGGF1 |
angiogenic factor with G patch and FHA domains 1 |
5 |
76361987 |
NM_018046 |
55109 |
5q13.3 |
Hs.634849 |
12 |
vasculogenesis positive regulation of endothelial cell proliferation nucleic acid binding protein binding extracellular region intracellular cytoplasm RNA processing cell adhesion multicellular organismal development eukaryotic cell surface binding positive regulation of angiogenesis perinuclear region of cytoplasm |
|
1568746_a_at |
hCG_1654703 |
hCG1654703 |
1 |
|
BC029599 |
646268 |
1q23.1 |
Hs.506902 |
1 |
|
|
217473_x_at |
SLC11A1 |
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 |
2 |
218954995 |
AF229163 |
6556 |
2q35 |
Hs.591607 |
106 |
transporter activity iron ion binding vacuole plasma membrane integral to plasma membrane ion transport iron ion transport cellular cadmium ion homeostasis cellular iron ion homeostasis response to bacterium phagocytic vesicle membrane protein homodimerization activity transition metal ion transmembrane transporter activity metal ion:hydrogen antiporter activity cadmium ion transmembrane transport |
Lysosome |
202931_x_at |
BIN1 |
bridging integrator 1 |
2 |
-127522077, -127522076 |
NM_004305 |
274 |
2q14 |
Hs.193163 |
69 |
protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms |
|
212380_at |
FTSJD2 |
FtsJ methyltransferase domain containing 2 |
6 |
37508884 |
D43949 |
23070 |
6p21.2 |
Hs.520102 |
7 |
nucleic acid binding protein binding intracellular methyltransferase activity transferase activity methylation |
|
220238_s_at |
0.275 |
3.260 |
2.270 |
3.814e-02 |
0.565 |
-3.681 |
KLHL7 |
kelch-like 7 (Drosophila) |
7 |
23111877 |
NM_018846 |
55975 |
7p15.3 |
Hs.654817 |
9 |
protein binding nucleus nucleolus |
|
214073_at |
CTTN |
cortactin |
11 |
69922259, 69922291 |
BG475299 |
2017 |
11q13 |
Hs.596164 |
106 |
ruffle protein binding soluble fraction cytoplasm cytoskeleton cell cortex lamellipodium |
Tight junction Pathogenic Escherichia coli infection - EHEC |
210513_s_at |
-0.325 |
6.267 |
-2.141 |
4.889e-02 |
0.590 |
-3.885 |
VEGFA |
vascular endothelial growth factor A |
6 |
43845930 |
AF091352 |
7422 |
6p12 |
Hs.73793 |
1447 |
angiogenesis vasculogenesis response to hypoxia positive regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation fibronectin binding positive regulation of leukocyte migration cytokine activity platelet-derived growth factor receptor binding extracellular region extracellular region proteinaceous extracellular matrix extracellular space multicellular organismal development nervous system development growth factor activity heparin binding regulation of cell shape cell surface membrane positive regulation of vascular endothelial growth factor receptor signaling pathway platelet alpha granule lumen protein homodimerization activity negative regulation of apoptosis vascular endothelial growth factor receptor 1 binding vascular endothelial growth factor receptor 2 binding cell surface binding positive regulation of blood vessel endothelial cell migration platelet-derived growth factor receptor signaling pathway extracellular matrix binding induction of positive chemotaxis |
Cytokine-cytokine receptor interaction mTOR signaling pathway VEGF signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer |
226120_at |
TTC8 |
tetratricopeptide repeat domain 8 |
14 |
88360730 |
AW293939 |
123016 |
14q31.3 |
Hs.303055 |
7 |
binding cytoplasm centrosome plasma membrane cilium visual perception cell projection organization BBSome response to stimulus cilium membrane |
|
208696_at |
0.353 |
8.894 |
2.564 |
2.143e-02 |
0.497 |
-3.200 |
CCT5 |
chaperonin containing TCP1, subunit 5 (epsilon) |
5 |
10303281 |
AF275798 |
22948 |
5p15.2 |
Hs.1600 |
30 |
nucleotide binding ATP binding nucleus nucleolus cytoplasm chaperonin-containing T-complex protein folding unfolded protein binding |
|
205072_s_at |
XRCC4 |
X-ray repair complementing defective repair in Chinese hamster cells 4 |
5 |
82409072 |
NM_022406 |
7518 |
5q13-q14 |
Hs.567359 |
93 |
condensed chromosome in utero embryonic development pro-B cell differentiation DNA binding nucleus nucleus cytosol DNA-dependent protein kinase-DNA ligase 4 complex double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining response to DNA damage stimulus central nervous system development protein C-terminus binding response to X-ray response to gamma radiation ligase activity provirus integration initiation of viral infection DNA ligase IV complex T cell differentiation in the thymus immunoglobulin V(D)J recombination negative regulation of neuron apoptosis isotype switching positive regulation of fibroblast proliferation positive regulation of neurogenesis DNA ligation during DNA repair positive regulation of ligase activity |
Non-homologous end-joining |
220044_x_at |
LUC7L3 |
LUC7-like 3 (S. cerevisiae) |
17 |
46151975 |
NM_016424 |
51747 |
17q21.33 |
Hs.130293 |
15 |
DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck |
|
228698_at |
SOX7 |
SRY (sex determining region Y)-box 7 |
8 |
-10618687 |
AI808807 |
83595 |
8p22 |
Hs.709543 |
11 |
transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter regulation of transcription |
|
235492_at |
0.311 |
5.412 |
2.257 |
3.909e-02 |
0.567 |
-3.701 |
RNF217 |
ring finger protein 217 |
6 |
125346212 |
AI888256 |
154214 |
6q22.31 |
Hs.368639 |
5 |
ubiquitin-protein ligase activity protein binding zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process protein ubiquitination during ubiquitin-dependent protein catabolic process metal ion binding |
|
1559901_s_at |
0.411 |
4.715 |
3.152 |
6.487e-03 |
0.364 |
-2.188 |
C21orf34 |
chromosome 21 open reading frame 34 |
21 |
16364712, 16488569 |
BM194465 |
388815 |
21q21.1 |
Hs.719301 |
5 |
|
|
219297_at |
WDR44 |
WD repeat domain 44 |
X |
117364069 |
NM_019045 |
54521 |
Xq24 |
Hs.98510 |
16 |
cytoplasm endosome Golgi apparatus cytosol endosome membrane membrane perinuclear region of cytoplasm |
|
228368_at |
ARHGAP20 |
Rho GTPase activating protein 20 |
11 |
-109952975 |
AI936560 |
57569 |
11q23.1 |
Hs.6136 |
7 |
GTPase activator activity intracellular signal transduction |
|
202724_s_at |
0.644 |
7.398 |
3.323 |
4.561e-03 |
0.332 |
-1.888 |
FOXO1 |
forkhead box O1 |
13 |
-40027800 |
NM_002015 |
2308 |
13q14.1 |
Hs.370666 |
140 |
blood vessel development transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent anti-apoptosis insulin receptor signaling pathway transcription activator activity regulation of cell proliferation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter |
Insulin signaling pathway Pathways in cancer Prostate cancer |
213789_at |
-0.223 |
5.459 |
-2.314 |
3.505e-02 |
0.555 |
-3.611 |
EBP |
emopamil binding protein (sterol isomerase) |
X |
48265107 |
N58493 |
10682 |
Xp11.23-p11.22 |
Hs.30619 |
19 |
C-8 sterol isomerase activity skeletal system development steroid delta-isomerase activity transmembrane receptor activity endoplasmic reticulum microsome integral to plasma membrane cholesterol biosynthetic process drug transporter activity membrane isomerase activity hemopoiesis cholestenol delta-isomerase activity |
Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
222498_at |
0.283 |
6.641 |
2.282 |
3.730e-02 |
0.562 |
-3.662 |
AZI2 |
5-azacytidine induced 2 |
3 |
-28348183, -28338850 |
AI809206 |
64343 |
3p24.1 |
Hs.706676 |
12 |
cytoplasm |
RIG-I-like receptor signaling pathway |
207055_at |
GPR37L1 |
G protein-coupled receptor 37 like 1 |
1 |
200358651 |
NM_004767 |
9283 |
1q32.1 |
Hs.132049 |
5 |
receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway biological_process integral to membrane |
|
224744_at |
IMPAD1 |
inositol monophosphatase domain containing 1 |
8 |
-58033041 |
AW628838 |
54928 |
8q12.1 |
Hs.716471 |
4 |
magnesium ion binding inositol-1(or 4)-monophosphatase activity membrane integral to membrane hydrolase activity |
|
202950_at |
CRYZ |
crystallin, zeta (quinone reductase) |
1 |
-74943762, -74943759 |
NM_001889 |
1429 |
1p31-p22 |
Hs.83114 |
14 |
NADPH:quinone reductase activity binding cytoplasm visual perception zinc ion binding oxidoreductase activity oxidation reduction |
|
222743_s_at |
0.374 |
7.073 |
3.727 |
1.979e-03 |
0.273 |
-1.178 |
C11orf71 |
chromosome 11 open reading frame 71 |
11 |
-113767379 |
AV721563 |
54494 |
11q14.2-q14.3 |
Hs.715083 |
3 |
|
|
207864_at |
SCN7A |
sodium channel, voltage-gated, type VII, alpha |
2 |
-166969784 |
NM_002976 |
6332 |
2q21-q23 |
Hs.695947 |
11 |
voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport muscle contraction membrane integral to membrane sodium ion binding |
|
202313_at |
PPP2R2A |
protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform |
8 |
26204950 |
NM_002717 |
5520 |
8p21.2 |
Hs.146339 |
44 |
protein phosphatase type 2A complex protein serine/threonine phosphatase activity protein binding protein amino acid dephosphorylation signal transduction protein phosphatase type 2A regulator activity response to morphine |
Tight junction |
228358_at |
SOX12 |
SRY (sex determining region Y)-box 12 |
20 |
254238 |
AI161357 |
6666 |
20p13 |
Hs.43627 Hs.712815 |
9 |
DNA binding RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter regulation of transcription |
|
217892_s_at |
LIMA1 |
LIM domain and actin binding 1 |
12 |
-48855829, -48855829 |
NM_016357 |
51474 |
12q13 |
Hs.525419 |
23 |
stress fiber actin monomer binding cytoplasm focal adhesion zinc ion binding actin cytoskeleton cell junction negative regulation of actin filament depolymerization ruffle organization metal ion binding actin filament binding actin filament bundle formation |
|
220554_at |
SLC22A7 |
solute carrier family 22 (organic anion transporter), member 7 |
6 |
43373975 |
NM_006672 |
10864 |
6p21.2-p21.1 |
Hs.485438 |
10 |
membrane fraction plasma membrane integral to plasma membrane ion transport ion transmembrane transporter activity sodium-independent organic anion transmembrane transporter activity organic anion transport |
|
1554500_a_at |
RGS7 |
regulator of G-protein signaling 7 |
1 |
-239005439 |
AF493931 |
6000 |
1q23.1 1q43 |
Hs.655739 |
23 |
signal transducer activity protein binding cellular_component heterotrimeric G-protein complex intracellular signaling cascade regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction |
|
218859_s_at |
ESF1 |
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
20 |
-13642968 |
NM_016649 |
51575 |
20p12.1 |
Hs.369284 |
10 |
nucleus nucleoplasm nucleolus regulation of transcription |
|
228024_at |
VPS37A |
vacuolar protein sorting 37 homolog A (S. cerevisiae) |
8 |
17148771 |
AW028100 |
137492 |
8p22 |
Hs.343873 Hs.512464 |
8 |
nucleus endosome protein transport membrane |
Endocytosis |
226581_at |
ZFYVE20 |
zinc finger, FYVE domain containing 20 |
3 |
-15086583 |
AA524034 |
64145 |
3p25.1 |
Hs.475565 Hs.706478 |
9 |
intracellular endosome plasma membrane zinc ion binding protein transport endosome transport metal ion binding |
Endocytosis |
1555704_at |
-0.273 |
3.831 |
-2.305 |
3.569e-02 |
0.556 |
-3.626 |
CMTM3 |
CKLF-like MARVEL transmembrane domain containing 3 |
16 |
65195702, 65195713, 65196067 |
AY166714 |
123920 |
16q21 |
Hs.298198 |
7 |
cytokine activity extracellular space chemotaxis membrane integral to membrane |
|
210818_s_at |
-0.214 |
2.702 |
-2.628 |
1.886e-02 |
0.488 |
-3.093 |
BACH1 |
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
21 |
29593090, 29593607, 29599430 |
AF026199 |
571 |
21q22.11 |
Hs.154276 |
30 |
transcription factor activity nucleus nucleolus cytosol regulation of transcription, DNA-dependent sequence-specific DNA binding protein dimerization activity |
|
214764_at |
RRP15 |
ribosomal RNA processing 15 homolog (S. cerevisiae) |
1 |
216525251 |
AW029169 |
51018 |
1q41 |
Hs.660109 |
8 |
protein binding |
|
242844_at |
0.333 |
5.604 |
2.276 |
3.771e-02 |
0.564 |
-3.672 |
PGGT1B |
protein geranylgeranyltransferase type I, beta subunit |
5 |
-114574425 |
AA989220 |
5229 |
5q22.3 |
Hs.254006 |
8 |
prenyltransferase activity CAAX-protein geranylgeranyltransferase activity CAAX-protein geranylgeranyltransferase complex zinc ion binding transferase activity protein amino acid geranylgeranylation metal ion binding |
|
227371_at |
BAIAP2L1 |
BAI1-associated protein 2-like 1 |
7 |
-97758903 |
AA496034 |
55971 |
7q21.3-q22.1 |
Hs.656063 Hs.710371 |
13 |
molecular_function actin binding cellular_component signal transduction cytoskeletal adaptor activity biological_process SH3 domain binding filopodium assembly |
|
229959_at |
KLKB1 |
kallikrein B, plasma (Fletcher factor) 1 |
4 |
187385665 |
BE670622 |
3818 |
4q34-q35 |
Hs.237642 |
46 |
Factor XII activation serine-type endopeptidase activity extracellular region extracellular space cytoplasm proteolysis inflammatory response blood coagulation peptidase activity plasminogen activation positive regulation of fibrinolysis |
Complement and coagulation cascades |
227689_at |
0.749 |
4.749 |
3.872 |
1.469e-03 |
0.250 |
-0.926 |
ZNF227 |
zinc finger protein 227 |
19 |
49408530 |
BF739795 |
7770 |
|
Hs.371335 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
1569737_a_at |
CASKIN1 |
CASK interacting protein 1 |
16 |
-2167184 |
BC042011 |
57524 |
16p13.3 |
Hs.643537 |
3 |
protein binding cytoplasm signal transduction |
|
203652_at |
-0.204 |
6.164 |
-2.209 |
4.295e-02 |
0.576 |
-3.779 |
MAP3K11 |
mitogen-activated protein kinase kinase kinase 11 |
11 |
-65121801 |
NM_002419 |
4296 |
11q13.1-q13.3 |
Hs.502872 |
44 |
G1 phase of mitotic cell cycle nucleotide binding protein serine/threonine kinase activity JUN kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding centrosome microtubule microtubule-based process activation of JUN kinase activity cell proliferation transferase activity protein homodimerization activity regulation of JNK cascade protein amino acid autophosphorylation protein oligomerization |
MAPK signaling pathway |
203523_at |
LSP1 |
lymphocyte-specific protein 1 |
11 |
1830775, 1846478, 1848674, 1848729 |
NM_002339 |
4046 |
11p15.5 |
Hs.56729 |
30 |
actin binding signal transducer activity plasma membrane cell motion cellular defense response signal transduction actin cytoskeleton |
|
203303_at |
0.455 |
7.416 |
2.613 |
1.942e-02 |
0.489 |
-3.117 |
DYNLT3 |
dynein, light chain, Tctex-type 3 |
X |
-37583033 |
NM_006520 |
6990 |
Xp21 |
Hs.446392 |
13 |
molecular_function motor activity protein binding cellular_component microtubule biological_process dynein complex |
|
201712_s_at |
RANBP2 |
RAN binding protein 2 |
2 |
108702368 |
NM_006267 |
5903 |
2q12.3 |
Hs.199561 Hs.715056 |
61 |
peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport |
|
211043_s_at |
CLTB |
clathrin, light chain (Lcb) |
5 |
-175752061 |
BC006332 |
1212 |
4q2-q3 5q35 |
Hs.484241 |
17 |
structural molecule activity calcium ion binding protein binding intracellular protein transport membrane vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle |
Lysosome Endocytosis Huntington's disease |
240396_at |
IL20RA |
interleukin 20 receptor, alpha |
6 |
-137362800 |
AI686661 |
53832 |
6q22.33-q23.1 |
Hs.445868 |
15 |
receptor activity cytokine receptor activity membrane integral to membrane |
Cytokine-cytokine receptor interaction Jak-STAT signaling pathway |
211982_x_at |
XPO6 |
exportin 6 |
16 |
-28016816 |
AL546600 |
23214 |
16p11.2 |
Hs.460468 |
11 |
protein import into nucleus, docking protein binding nucleus nuclear pore cytoplasm protein export from nucleus intracellular protein transport protein transporter activity |
|
214464_at |
0.532 |
7.215 |
2.811 |
1.304e-02 |
0.433 |
-2.781 |
CDC42BPA |
CDC42 binding protein kinase alpha (DMPK-like) |
1 |
-225244188 |
NM_003607 |
8476 |
1q42.11 |
Hs.35433 |
20 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity small GTPase regulator activity ATP binding cytoplasm cell-cell junction protein amino acid phosphorylation intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding cell leading edge actin cytoskeleton reorganization identical protein binding |
|
205073_at |
CYP2J2 |
cytochrome P450, family 2, subfamily J, polypeptide 2 |
1 |
-60131567 |
NM_000775 |
1573 |
1p31.3-p31.2 |
Hs.152096 |
50 |
endoplasmic reticulum microsome fatty acid metabolic process icosanoid metabolic process regulation of heart contraction arachidonic acid epoxygenase activity electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity |
Arachidonic acid metabolism Linoleic acid metabolism Metabolic pathways |
207489_at |
RPS2P45 |
ribosomal protein S2 pseudogene 45 |
16 |
|
NM_024986 |
80052 |
16q22.1 |
Hs.661121 |
3 |
|
|
210011_s_at |
0.306 |
6.699 |
4.259 |
6.660e-04 |
0.211 |
-0.258 |
EWSR1 |
Ewing sarcoma breakpoint region 1 |
22 |
27993997, 27993997 |
BC000527 |
2130 |
22q12.2 |
Hs.374477 |
90 |
nucleotide binding RNA binding calmodulin binding intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding |
|
213067_at |
0.613 |
4.812 |
2.721 |
1.562e-02 |
0.459 |
-2.934 |
MYH10 |
myosin, heavy chain 10, non-muscle |
17 |
-8318254 |
AI382123 |
4628 |
17p13 |
Hs.16355 |
37 |
microfilament motor activity nucleotide binding cytokinesis after mitosis in utero embryonic development stress fiber neuron migration plasma membrane repair calmodulin binding ATP binding cytoplasm spindle plasma membrane cell cortex exocytosis substrate-bound cell migration, cell extension nuclear migration axon guidance brain development adult heart development biological_process cell proliferation regulation of cell shape myosin complex fourth ventricle development lateral ventricle development third ventricle development cerebellar Purkinje cell layer development actin cytoskeleton organization actin filament-based movement axon growth cone midbody actin-dependent ATPase activity neuron projection development neuromuscular junction cleavage furrow cell soma dendritic spine ADP binding neuromuscular process controlling balance actin filament binding cardiac myofibril assembly ventricular cardiac muscle cell development retina development in camera-type eye |
Tight junction Regulation of actin cytoskeleton |
208058_s_at |
MGAT3 |
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
22 |
38183270, 38213174 |
NM_002409 |
4248 |
22q13.1 |
Hs.276808 |
17 |
beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Golgi apparatus protein amino acid N-linked glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups |
N-Glycan biosynthesis Metabolic pathways |
223140_s_at |
0.381 |
7.950 |
2.976 |
9.301e-03 |
0.401 |
-2.495 |
DHX36 |
DEAH (Asp-Glu-Ala-His) box polypeptide 36 |
3 |
-155476150 |
AF217190 |
170506 |
3p13-q23 |
Hs.446270 |
13 |
nucleotide binding nucleic acid binding helicase activity protein binding ATP binding nucleus cytoplasm ATP-dependent helicase activity hydrolase activity |
|
205032_at |
ITGA2 |
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
5 |
52320912 |
NM_002203 |
3673 |
5q23-q31 |
Hs.482077 |
235 |
magnesium ion binding receptor activity calcium ion binding collagen binding plasma membrane plasma membrane cell adhesion cell-matrix adhesion integrin-mediated signaling pathway blood coagulation integrin complex organ morphogenesis external side of plasma membrane integral to membrane identical protein binding interspecies interaction between organisms |
Focal adhesion ECM-receptor interaction Hematopoietic cell lineage Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
225346_at |
0.535 |
6.759 |
3.047 |
8.046e-03 |
0.386 |
-2.371 |
MTERFD3 |
MTERF domain containing 3 |
12 |
-105895198 |
NM_025198 |
80298 |
12q24.1 |
Hs.5009 |
6 |
mitochondrion transcription termination regulation of transcription |
|
232149_s_at |
0.351 |
5.613 |
2.137 |
4.920e-02 |
0.590 |
-3.890 |
NSMAF |
neutral sphingomyelinase (N-SMase) activation associated factor |
8 |
-59658619, -59658619 |
BF056507 |
8439 |
8q12-q13 |
Hs.372000 |
8 |
receptor signaling protein activity soluble fraction cytoplasm ceramide metabolic process signal transduction |
|
220311_at |
0.461 |
4.626 |
3.037 |
8.218e-03 |
0.387 |
-2.389 |
N6AMT1 |
N-6 adenine-specific DNA methyltransferase 1 (putative) |
21 |
-29166383 |
NM_013240 |
29104 |
21q21.3 |
Hs.163846 |
6 |
nucleic acid binding protein binding protein methyltransferase activity transferase activity positive regulation of cell growth methylation protein complex |
|
202261_at |
VPS72 |
vacuolar protein sorting 72 homolog (S. cerevisiae) |
1 |
-149415557 |
NM_005997 |
6944 |
1q21 |
Hs.2430 |
10 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity RNA polymerase II transcription factor activity nucleus chromatin modification protein complex regulation of transcription |
|
240282_at |
WDR1 |
WD repeat domain 1 |
4 |
-9685060 |
AW770902 |
9948 |
4p16.1 |
Hs.128548 Hs.713658 |
15 |
actin binding protein binding cytoplasm cytoskeleton sensory perception of sound |
|
202381_at |
0.343 |
7.704 |
2.345 |
3.299e-02 |
0.550 |
-3.561 |
ADAM9 |
ADAM metallopeptidase domain 9 (meltrin gamma) |
8 |
38973661, 38973661 |
NM_003816 |
8754 |
8p11.22 |
Hs.591852 |
36 |
activation of MAPKK activity metalloendopeptidase activity protein kinase C binding integrin binding integrin binding integrin binding collagen binding extracellular region extracellular space cytoplasm plasma membrane proteolysis response to oxidative stress cell-matrix adhesion transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway peptidase activity zinc ion binding cell surface response to manganese ion integral to membrane SH3 domain binding SH3 domain binding keratinocyte differentiation intrinsic to external side of plasma membrane positive regulation of cell adhesion mediated by integrin cell-cell adhesion mediated by integrin positive regulation of macrophage fusion response to tumor necrosis factor monocyte activation response to hydrogen peroxide laminin binding metal ion binding positive regulation of protein secretion positive regulation of membrane protein ectodomain proteolysis PMA-inducible membrane protein ectodomain proteolysis response to glucocorticoid stimulus positive regulation of keratinocyte migration response to calcium ion |
|
201860_s_at |
0.366 |
5.248 |
2.434 |
2.771e-02 |
0.527 |
-3.415 |
PLAT |
plasminogen activator, tissue |
8 |
-42151392 |
NM_000930 |
5327 |
8p12 |
Hs.491582 |
209 |
serine-type endopeptidase activity extracellular region extracellular region extracellular space protein modification process proteolysis blood coagulation peptidase activity |
Complement and coagulation cascades |
222975_s_at |
0.325 |
10.872 |
2.156 |
4.752e-02 |
0.585 |
-3.862 |
CSDE1 |
cold shock domain containing E1, RNA-binding |
1 |
-115061060, -115061060, -115061059 |
AI423180 |
7812 |
1p22 |
Hs.69855 |
25 |
DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development |
|
228716_at |
THRB |
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) |
3 |
-24133648, -24133648 |
BG494007 |
7068 |
3p24.2 |
Hs.187861 |
130 |
double-stranded DNA binding transcription factor activity steroid hormone receptor activity transcription corepressor activity thyroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent sensory perception of sound regulation of heart contraction zinc ion binding organ morphogenesis negative regulation of transcription regulation of lipid metabolic process positive regulation of chondrocyte differentiation protein homodimerization activity sequence-specific DNA binding positive regulation of ossification positive regulation of transcription from RNA polymerase II promoter metal ion binding |
Neuroactive ligand-receptor interaction |
229238_at |
-0.860 |
5.077 |
-2.759 |
1.447e-02 |
0.447 |
-2.869 |
C17orf97 |
chromosome 17 open reading frame 97 |
17 |
260433 |
BE552331 |
400566 |
17p13.3 |
Hs.499607 |
1 |
|
|
238935_at |
RPS27L |
ribosomal protein S27-like |
15 |
-61232591 |
AW958475 |
51065 |
15q22.2 |
Hs.108957 |
6 |
structural constituent of ribosome intracellular nucleus ribosome DNA repair translation response to DNA damage stimulus zinc ion binding translation activator activity caspase activator activity G1 DNA damage checkpoint DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis positive regulation of anti-apoptosis metal ion binding |
|
236070_at |
-0.181 |
5.882 |
-2.573 |
2.103e-02 |
0.497 |
-3.184 |
C2orf81 |
chromosome 2 open reading frame 81 |
2 |
-74494810 |
AA720997 |
388963 |
2p13.1 |
Hs.445377 |
1 |
|
|
236225_at |
GGT6 |
gamma-glutamyltransferase 6 |
17 |
-4406970 |
AI697028 |
124975 |
17p13.2 |
Hs.130749 |
5 |
gamma-glutamyltransferase activity glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity |
Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways |
207990_x_at |
-0.341 |
4.089 |
-2.919 |
1.045e-02 |
0.418 |
-2.593 |
ACRV1 |
acrosomal vesicle protein 1 |
11 |
-125047438 |
NM_020114 |
56 |
11q23-q24 |
Hs.169222 Hs.596575 |
12 |
acrosomal vesicle multicellular organismal development |
|
219355_at |
CXorf57 |
chromosome X open reading frame 57 |
X |
105741815 |
NM_018015 |
55086 |
Xq22.3 |
Hs.274267 |
5 |
|
|
201306_s_at |
0.420 |
9.127 |
2.627 |
1.890e-02 |
0.488 |
-3.094 |
ANP32B |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
9 |
99785309 |
NM_006401 |
10541 |
9q22.32 |
Hs.715547 |
16 |
protein binding nucleus |
|
225162_at |
SH3D19 |
SH3 domain containing 19 |
4 |
-152260882, -152260882 |
BG285417 |
152503 |
4q31.3 |
Hs.567725 |
12 |
nucleus nucleolus cytoplasm Golgi apparatus plasma membrane positive regulation of membrane protein ectodomain proteolysis |
|
220664_at |
SPRR2C |
small proline-rich protein 2C (pseudogene) |
1 |
-151379217 |
NM_006518 |
6702 |
1q21-q22 |
Hs.2421 |
5 |
|
|
225378_at |
0.487 |
6.877 |
2.160 |
4.710e-02 |
0.584 |
-3.855 |
VPS37A |
vacuolar protein sorting 37 homolog A (S. cerevisiae) |
8 |
17148771 |
AI866426 |
137492 |
8p22 |
Hs.343873 Hs.512464 |
8 |
nucleus endosome protein transport membrane |
Endocytosis |
205246_at |
PEX13 |
peroxisomal biogenesis factor 13 |
2 |
61098315 |
NM_002618 |
5194 |
2p14-p16 |
Hs.161377 |
21 |
fatty acid alpha-oxidation neuron migration suckling behavior protein binding membrane fraction peroxisome peroxisomal membrane integral to peroxisomal membrane locomotory behavior protein transport membrane integral to membrane protein import into peroxisome matrix, docking protein import into peroxisome matrix, docking cerebral cortex cell migration microtubule-based peroxisome localization |
|
206021_at |
-0.283 |
4.693 |
-2.140 |
4.892e-02 |
0.590 |
-3.886 |
SCAND2 |
SCAN domain containing 2 pseudogene |
15 |
82975694 |
NM_022050 |
54581 |
15q25-q26 |
Hs.658114 |
7 |
molecular_function transcription factor activity cellular_component nucleus regulation of transcription, DNA-dependent biological_process |
|
221665_s_at |
EPS8L1 |
EPS8-like 1 |
19 |
60279032, 60283571 |
BC004907 |
54869 |
19q13.42 |
Hs.438862 |
8 |
molecular_function cellular_component cytoplasm biological_process |
|
1570173_at |
INTS7 |
integrator complex subunit 7 |
1 |
-210181320 |
BC036009 |
25896 |
1p36.13-q42.3 |
Hs.369285 |
8 |
protein binding nucleus snRNA processing integrator complex |
|
207657_x_at |
0.276 |
8.286 |
2.628 |
1.885e-02 |
0.488 |
-3.092 |
TNPO1 |
transportin 1 |
5 |
72148173, 72179685 |
NM_002270 |
3842 |
5q13.2 |
Hs.482497 |
58 |
protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
226221_at |
KIAA1432 |
KIAA1432 |
9 |
5619326, 5646582 |
AL138104 |
57589 |
9p24.1 |
Hs.211520 |
5 |
membrane integral to membrane |
|
203261_at |
0.289 |
8.809 |
3.288 |
4.899e-03 |
0.341 |
-1.949 |
DCTN6 |
dynactin 6 |
8 |
30133354 |
NM_006571 |
10671 |
8p12-p11 |
Hs.146585 |
6 |
cytoplasm cytoskeleton dynactin complex transferase activity dynein binding |
|
211489_at |
ADRA1A |
adrenergic, alpha-1A-, receptor |
8 |
-26683138, -26679287, -26669829, -26661583 |
D32201 |
148 |
8p21-p11.2 |
Hs.709175 |
67 |
receptor activity G-protein coupled receptor activity adrenoceptor activity alpha1-adrenergic receptor activity alpha1-adrenergic receptor activity plasma membrane integral to plasma membrane apoptosis smooth muscle contraction signal transduction G-protein coupled receptor protein signaling pathway protein kinase cascade cell-cell signaling negative regulation of cell proliferation |
Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction |
222855_s_at |
-0.313 |
4.377 |
-2.851 |
1.202e-02 |
0.426 |
-2.712 |
TRPV2 |
transient receptor potential cation channel, subfamily V, member 2 |
17 |
16259612 |
BF058747 |
51393 |
17p11.2 |
Hs.279746 |
18 |
calcium channel activity calcium ion binding intracellular cytoplasm plasma membrane integral to plasma membrane ion transport calcium ion transport sensory perception response to temperature stimulus melanosome |
|
1561908_a_at |
HS3ST3B1 |
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 |
17 |
14145230 |
AL832823 |
9953 |
17p12-p11.2 |
Hs.48384 |
10 |
Golgi apparatus integral to plasma membrane sulfotransferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane transferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity |
Glycosaminoglycan degradation Heparan sulfate biosynthesis |
200969_at |
0.437 |
6.095 |
2.883 |
1.125e-02 |
0.426 |
-2.656 |
SERP1 |
stress-associated endoplasmic reticulum protein 1 |
3 |
-151742469 |
BG107676 |
27230 |
3q25.1 |
Hs.518326 Hs.709270 |
10 |
skeletal system development endoplasmic reticulum ribosome glucose metabolic process protein amino acid glycosylation response to stress plasma membrane organization post-embryonic development multicellular organismal aging protein transport membrane integral to membrane endoplasmic reticulum unfolded protein response positive regulation of insulin secretion positive regulation of translation positive regulation of organ growth muscle organ morphogenesis positive regulation of growth hormone secretion intracellular protein transmembrane transport |
|
1568680_s_at |
YTHDC2 |
YTH domain containing 2 |
5 |
112877308 |
BC019100 |
64848 |
5q22.2 |
Hs.231942 |
6 |
nucleotide binding nucleic acid binding helicase activity ATP binding hydrolase activity |
|
209250_at |
0.472 |
7.134 |
3.596 |
2.596e-03 |
0.287 |
-1.409 |
DEGS1 |
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) |
1 |
222437550 |
BC000961 |
8560 |
1q42.11 |
Hs.299878 |
5 |
protein binding membrane fraction endoplasmic reticulum integral to plasma membrane unsaturated fatty acid biosynthetic process electron carrier activity membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidation reduction |
Sphingolipid metabolism Metabolic pathways |
213146_at |
-0.254 |
4.838 |
-2.281 |
3.738e-02 |
0.562 |
-3.664 |
KDM6B |
lysine (K)-specific demethylase 6B |
17 |
7683959 |
AA521267 |
23135 |
17p13.1 |
Hs.223678 |
8 |
negative regulation of transcription from RNA polymerase II promoter binding iron ion binding nucleus inflammatory response oxidoreductase activity chromatin modification histone demethylation oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen sequence-specific DNA binding metal ion binding oxidation reduction |
|
219029_at |
0.443 |
4.733 |
2.198 |
4.382e-02 |
0.578 |
-3.795 |
C5orf28 |
chromosome 5 open reading frame 28 |
5 |
-43480110 |
NM_022483 |
64417 |
5p12 |
Hs.558531 |
5 |
membrane integral to membrane |
|
207309_at |
NOS1 |
nitric oxide synthase 1 (neuronal) |
12 |
-116135361 |
NM_000620 |
4842 |
12q24.2-q24.31 |
Hs.654410 |
188 |
response to hypoxia photoreceptor inner segment nitric-oxide synthase activity calmodulin binding cytoplasm cytoskeleton arginine catabolic process nitric oxide biosynthetic process myoblast fusion electron carrier activity response to heat FMN binding negative regulation of calcium ion transport into cytosol oxidoreductase activity sarcoplasmic reticulum heme binding multicellular organismal response to stress tetrahydrobiopterin binding arginine binding neurotransmitter biosynthetic process sarcolemma cell projection dendritic spine positive regulation of vasodilation positive regulation of vasodilation cadmium ion binding metal ion binding perinuclear region of cytoplasm FAD binding NADP or NADPH binding oxidation reduction regulation of cardiac muscle contraction |
Arginine and proline metabolism Metabolic pathways Calcium signaling pathway Long-term depression Alzheimer's disease Amyotrophic lateral sclerosis (ALS) Pathways in cancer Small cell lung cancer |
203841_x_at |
0.375 |
4.718 |
2.722 |
1.559e-02 |
0.459 |
-2.932 |
MAPRE3 |
microtubule-associated protein, RP/EB family, member 3 |
2 |
27047028 |
BG222594 |
22924 |
2p23.3-p23.1 |
Hs.515860 |
13 |
small GTPase regulator activity cytoplasm microtubule cell cycle mitosis microtubule binding midbody positive regulation of gene-specific transcription cell division |
|
213899_at |
METAP2 |
methionyl aminopeptidase 2 |
12 |
94391952 |
AI743685 |
10988 |
12q22 |
Hs.444986 |
35 |
aminopeptidase activity cytoplasm proteolysis peptidase activity metalloexopeptidase activity cellular process protein processing peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding |
|
224694_at |
0.860 |
7.193 |
3.428 |
3.674e-03 |
0.314 |
-1.704 |
ANTXR1 |
anthrax toxin receptor 1 |
2 |
69093779, 69093779, 69093779 |
AF279145 |
84168 |
2p13.1 |
Hs.165859 |
24 |
transmembrane receptor activity collagen binding membrane integral to membrane lamellipodium membrane filopodium membrane actin cytoskeleton reorganization substrate adhesion-dependent cell spreading metal ion binding actin filament binding |
|
237536_at |
LOC100128977 |
hypothetical LOC100128977 |
17 |
-41276503 |
AW450849 |
100128977 |
17q21.31 |
Hs.666302 |
2 |
|
|
244084_at |
AIFM3 |
apoptosis-inducing factor, mitochondrion-associated, 3 |
22 |
19649417, 19651446 |
AA468769 |
150209 |
22q11.21 |
Hs.163543 |
9 |
iron ion binding nucleus cytoplasm mitochondrion mitochondrial inner membrane endoplasmic reticulum cytosol plasma membrane transport apoptosis induction of apoptosis activation of caspase activity by cytochrome c caspase activator activity electron carrier activity oxidoreductase activity electron transport chain cell redox homeostasis metal ion binding FAD binding 2 iron, 2 sulfur cluster binding mitochondrial depolarization |
|
228263_at |
GRASP |
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein |
12 |
50687014 |
AI190755 |
160622 |
12q13.13 |
Hs.407202 |
7 |
protein binding cytoplasm plasma membrane signal transduction cell junction synapse postsynaptic membrane perinuclear region of cytoplasm |
|
1556960_a_at |
hCG_2007354 |
hCG2007354 |
12 |
|
AK057223 |
647589 |
12q24.33 |
Hs.703008 |
2 |
|
|
224822_at |
DLC1 |
deleted in liver cancer 1 |
8 |
-13116452, -12985242, -12985242 |
AA524250 |
10395 |
8p22 |
Hs.134296 |
48 |
neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation |
|
204127_at |
RFC3 |
replication factor C (activator 1) 3, 38kDa |
13 |
33290205, 33290205 |
BC000149 |
5983 |
13q12.3-q13 |
Hs.115474 |
29 |
nucleotide binding DNA synthesis during DNA repair DNA clamp loader activity protein binding nucleus nucleoplasm DNA replication factor C complex DNA replication factor C complex DNA strand elongation during DNA replication nucleotide-excision repair, DNA gap filling ATPase activity response to organophosphorus |
DNA replication Nucleotide excision repair Mismatch repair |
228801_at |
ORMDL1 |
ORM1-like 1 (S. cerevisiae) |
2 |
-190343237 |
AI809749 |
94101 |
2q32 |
Hs.709387 |
7 |
endoplasmic reticulum endoplasmic reticulum membrane membrane integral to membrane |
|
212260_at |
GIGYF2 |
GRB10 interacting GYF protein 2 |
2 |
233270258 |
AL045800 |
26058 |
2q37.1 |
Hs.565319 |
23 |
protein binding |
|
230686_s_at |
SLC13A3 |
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
20 |
-44619869, -44619869 |
AI634662 |
64849 |
20q12-q13.1 |
Hs.655498 |
12 |
transporter activity centrosome plasma membrane ion transport sodium ion transport symporter activity integral to membrane cell junction sodium ion binding |
|
223600_s_at |
KIAA1683 |
KIAA1683 |
19 |
-18228906 |
AL136867 |
80726 |
19p13.1 |
Hs.313471 |
12 |
mitochondrion |
|
209400_at |
SLC12A4 |
solute carrier family 12 (potassium/chloride transporters), member 4 |
16 |
-66534877, -66534877, -66534877 |
U55054 |
6560 |
16q22.1 |
Hs.10094 |
16 |
transporter activity membrane fraction integral to plasma membrane ion transport potassium ion transport sodium ion transport chloride transport cell volume homeostasis symporter activity potassium:chloride symporter activity membrane potassium ion binding |
|
238231_at |
NFYC |
nuclear transcription factor Y, gamma |
1 |
40929828, 40930266 |
AV700263 |
4802 |
1p32 |
Hs.233458 Hs.713051 |
24 |
transcription factor activity RNA polymerase II transcription factor activity transcription coactivator activity protein binding intracellular nucleus regulation of transcription from RNA polymerase II promoter protein folding CCAAT-binding factor complex sequence-specific DNA binding |
Antigen processing and presentation |
214285_at |
FABP3 |
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) |
1 |
-31610686 |
AI041520 |
2170 |
1p33-p32 |
Hs.657242 |
35 |
transporter activity cytoplasm phosphatidylcholine biosynthetic process transport negative regulation of cell proliferation lipid binding |
PPAR signaling pathway |
225116_at |
HIPK2 |
homeodomain interacting protein kinase 2 |
7 |
-138896855 |
AW300045 |
28996 |
7q32-q34 |
Hs.397465 Hs.632033 |
66 |
nucleotide binding transcription corepressor activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation apoptosis DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator induction of apoptosis by intracellular signals PML body transferase activity virus-host interaction positive regulation of transforming growth factor beta receptor signaling pathway nuclear membrane regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of JNK cascade virion binding |
|
1553978_at |
0.314 |
7.048 |
2.532 |
2.281e-02 |
0.503 |
-3.252 |
LOC729991 |
hypothetical protein LOC729991 |
19 |
-19153684, -19148713 |
BC010931 |
729991 |
19p13.11 |
Hs.153629 |
6 |
protein binding |
|
232631_at |
-0.330 |
4.685 |
-2.367 |
3.162e-02 |
0.544 |
-3.525 |
CDH6 |
cadherin 6, type 2, K-cadherin (fetal kidney) |
5 |
31229552 |
AU150574 |
1004 |
5p15.1-p14 |
Hs.171054 |
14 |
calcium ion binding protein binding nucleus cytoplasm plasma membrane cell adhesion homophilic cell adhesion female gonad development integral to membrane |
|
205168_at |
DDR2 |
discoidin domain receptor tyrosine kinase 2 |
1 |
160868851 |
NM_006182 |
4921 |
1q23.3 |
Hs.275757 Hs.593833 |
26 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation cell adhesion signal transduction transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell proliferation membrane transferase activity |
|
203076_s_at |
0.318 |
7.236 |
2.214 |
4.247e-02 |
0.575 |
-3.770 |
SMAD2 |
SMAD family member 2 |
18 |
-43613464, -43613463, -43613463 |
U65019 |
4087 |
18q21.1 |
Hs.12253 Hs.705764 |
206 |
mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol |
Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer |
223519_at |
ZAK |
sterile alpha motif and leucine zipper containing kinase AZK |
2 |
173648810, 173648810 |
AW069181 |
51776 |
2q24.2 |
Hs.444451 |
24 |
cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis |
MAPK signaling pathway Tight junction |
209026_x_at |
0.680 |
9.366 |
2.634 |
1.861e-02 |
0.486 |
-3.082 |
TUBB |
tubulin, beta |
6 |
30796135, 2136731, 1935034 |
AF141349 |
203068 |
6p21.33 |
Hs.636480 Hs.706187 Hs.714425 |
39 |
nucleotide binding GTPase activity structural constituent of cytoskeleton GTP binding cytoskeleton microtubule cell motion microtubule-based movement flotillin complex natural killer cell mediated cytotoxicity MHC class I protein binding spindle assembly protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
216419_at |
CROCC |
ciliary rootlet coiled-coil, rootletin |
1 |
17121031 |
AK026910 |
9696 |
1pter-p36.11 |
Hs.309403 |
10 |
structural molecule activity protein binding centriole cell cycle protein localization kinesin binding cell projection organization ciliary rootlet centrosome organization |
|
206899_at |
-0.462 |
4.901 |
-3.715 |
2.029e-03 |
0.273 |
-1.199 |
NTSR2 |
neurotensin receptor 2 |
2 |
-11715754 |
NM_012344 |
23620 |
2p25.1 |
Hs.131138 |
14 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger sensory perception neurotensin receptor activity, G-protein coupled regulation of membrane potential |
Neuroactive ligand-receptor interaction |
230906_at |
0.246 |
5.108 |
2.807 |
1.313e-02 |
0.433 |
-2.787 |
GALNT10 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) |
5 |
153550487, 153763529 |
AK024931 |
55568 |
5q33.2 |
Hs.651323 Hs.655011 |
6 |
polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus protein amino acid O-linked glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding |
O-Glycan biosynthesis Metabolic pathways |
228878_s_at |
CFC1B |
cripto, FRL-1, cryptic family 1B |
2 |
-131066822, 130995136 |
BE550131 |
653275 |
2q21.1 |
Hs.503733 |
1 |
|
|
220358_at |
-0.216 |
5.589 |
-2.537 |
2.259e-02 |
0.501 |
-3.244 |
BATF3 |
basic leucine zipper transcription factor, ATF-like 3 |
1 |
-210926381 |
NM_018664 |
55509 |
1q32.3 |
Hs.62919 |
7 |
transcription factor activity transcription corepressor activity nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity |
|
1555562_a_at |
ZCCHC7 |
zinc finger, CCHC domain containing 7 |
9 |
37110468 |
BC022434 |
84186 |
9p13.2 |
Hs.654700 |
6 |
nucleic acid binding zinc ion binding metal ion binding |
RNA degradation |
238711_s_at |
ZNF148 |
zinc finger protein 148 |
3 |
-126427202 |
AI669304 |
7707 |
3q21 |
Hs.592591 |
34 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular nucleus DNA-directed RNA polymerase II, core complex nucleolus Golgi apparatus cellular defense response gamete generation zinc ion binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding |
|
212535_at |
0.230 |
8.997 |
2.185 |
4.493e-02 |
0.581 |
-3.816 |
MEF2A |
myocyte enhancer factor 2A |
15 |
97923655, 97990705 |
AA142929 |
4205 |
15q26 |
Hs.268675 |
77 |
transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding |
|
207024_at |
0.501 |
6.034 |
3.548 |
2.864e-03 |
0.297 |
-1.492 |
CHRND |
cholinergic receptor, nicotinic, delta |
2 |
233099165 |
NM_000751 |
1144 |
2q33-q34 |
Hs.156289 |
21 |
nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity protein binding plasma membrane nicotinic acetylcholine-gated receptor-channel complex ion transport muscle contraction signal transduction integral to membrane cell junction neurotransmitter receptor activity acetylcholine binding regulation of membrane potential synapse postsynaptic membrane skeletal muscle tissue growth musculoskeletal movement neuromuscular process |
|
217766_s_at |
0.451 |
6.749 |
2.742 |
1.497e-02 |
0.453 |
-2.898 |
TMEM50A |
transmembrane protein 50A |
1 |
25537397 |
NM_014313 |
23585 |
1p36.11 |
Hs.523054 |
13 |
cytoplasm endoplasmic reticulum membrane integral to membrane |
|
240329_at |
-0.323 |
4.539 |
-2.913 |
1.058e-02 |
0.418 |
-2.604 |
LOC727916 |
hypothetical protein LOC727916 |
6 |
|
AW136267 |
727916 |
6q12 |
Hs.706850 |
1 |
|
|
1554476_x_at |
ZNF808 |
zinc finger protein 808 |
19 |
57722720 |
BC033230 |
388558 |
19q13.41 |
Hs.235167 |
2 |
DNA binding intracellular nucleus transcription regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
201991_s_at |
KIF5B |
kinesin family member 5B |
10 |
-32337943 |
BF223224 |
3799 |
10pter-q22.1 |
Hs.644646 |
36 |
nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule-based movement cytoplasm organization microtubule binding ciliary rootlet neuron projection membrane-bounded organelle vesicle transport along microtubule perinuclear region of cytoplasm |
|
212263_at |
QKI |
quaking homolog, KH domain RNA binding (mouse) |
6 |
163755664, 163755664 |
AI114716 |
9444 |
6q26 6q26-q27 |
Hs.510324 Hs.593520 |
23 |
RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport |
|
234027_at |
CCDC129 |
coiled-coil domain containing 129 |
7 |
31523502 |
AI184130 |
223075 |
7p14.3 |
Hs.224269 |
2 |
|
|
222231_s_at |
0.468 |
6.555 |
3.203 |
5.839e-03 |
0.357 |
-2.099 |
LRRC59 |
leucine rich repeat containing 59 |
17 |
-45813597 |
AK025328 |
55379 |
17q21.33 |
Hs.370927 |
6 |
protein binding endoplasmic reticulum microsome membrane integral to membrane mitochondrial nucleoid |
|
205841_at |
JAK2 |
Janus kinase 2 |
9 |
4975244 |
NM_004972 |
3717 |
9p24 |
Hs.656213 |
588 |
nucleotide binding non-membrane spanning protein tyrosine kinase activity Janus kinase activity receptor binding growth hormone receptor binding interleukin-12 receptor binding ATP binding nucleus cytoplasm cytoskeleton caveola apoptosis cell motion enzyme linked receptor protein signaling pathway tyrosine phosphorylation of STAT protein STAT protein nuclear translocation mesoderm development negative regulation of cell proliferation positive regulation of phosphoinositide 3-kinase cascade membrane transferase activity myeloid cell differentiation SH2 domain binding positive regulation of tyrosine phosphorylation of Stat3 protein positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of DNA binding response to antibiotic positive regulation of peptidyl-tyrosine phosphorylation JAK-STAT cascade involved in growth hormone signaling pathway positive regulation of growth hormone receptor signaling pathway |
Chemokine signaling pathway Jak-STAT signaling pathway Adipocytokine signaling pathway |
229344_x_at |
RIMKLB |
ribosomal modification protein rimK-like family member B |
12 |
8741784 |
AW135012 |
57494 |
12p13.31 |
Hs.504670 |
4 |
nucleotide binding catalytic activity ATP binding protein modification process manganese ion binding metal ion binding |
|
207236_at |
ZNF345 |
zinc finger protein 345 |
19 |
42033106 |
NM_003419 |
25850 |
19q13.12 |
Hs.362324 |
5 |
negative regulation of transcription from RNA polymerase II promoter DNA binding specific RNA polymerase II transcription factor activity RNA polymerase III transcription factor activity intracellular nucleus regulation of transcription from RNA polymerase III promoter zinc ion binding regulation of transcription metal ion binding |
|
202383_at |
KDM5C |
lysine (K)-specific demethylase 5C |
X |
-53237228 |
NM_004187 |
8242 |
Xp11.22-p11.21 |
Hs.631768 |
17 |
molecular_function DNA binding iron ion binding protein binding cellular_component intracellular nucleus biological_process zinc ion binding oxidoreductase activity chromatin modification oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen regulation of transcription metal ion binding oxidation reduction |
|
215590_x_at |
-0.431 |
6.356 |
-2.655 |
1.784e-02 |
0.475 |
-3.046 |
LOC100128640 |
hypothetical protein LOC100128640 |
3 |
|
AK025619 |
100128640 |
3p22.2 |
|
|
|
|
216924_s_at |
DRD2 |
dopamine receptor D2 |
11 |
-112785526 |
S62137 |
1813 |
11q23 |
Hs.73893 |
519 |
temperature homeostasis dopamine D2 receptor activity response to amphetamine neurological system process involved in regulation of systemic arterial blood pressure regulation of heart rate regulation of sodium ion transport positive regulation of neuroblast proliferation receptor activity G-protein coupled receptor activity dopamine receptor activity protein binding plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway nerve-nerve synaptic transmission axonogenesis synaptogenesis sensory perception of smell locomotory behavior adult walking behavior protein localization drug binding negative regulation of cell proliferation associative learning visual learning response to light stimulus cerebral cortex GABAergic interneuron migration adenohypophysis development diuresis natriuresis negative regulation of cell migration phosphoinositide metabolic process axon dendrite peristalsis regulation of cAMP metabolic process regulation of synaptic transmission, GABAergic circadian regulation of gene expression response to histamine dopamine metabolic process response to drug regulation of potassium ion transport response to morphine negative regulation of blood pressure behavioral response to cocaine behavioral response to ethanol regulation of long-term neuronal synaptic plasticity branching morphogenesis of a nerve arachidonic acid secretion negative regulation of protein secretion release of sequestered calcium ion into cytosol positive regulation of dopamine uptake negative regulation of protein kinase B signaling cascade negative regulation of synaptic transmission, glutamatergic positive regulation of growth hormone secretion prepulse inhibition activation of phospholipase C activity by dopamine receptor signaling pathway negative regulation of dopamine receptor signaling pathway |
Neuroactive ligand-receptor interaction Gap junction |
1554033_at |
FRMD4A |
FERM domain containing 4A |
10 |
-13725711 |
BC018891 |
55691 |
10p13 |
Hs.330463 Hs.656573 |
3 |
binding cytoplasm cytoskeleton |
|
221474_at |
0.472 |
10.442 |
3.486 |
3.256e-03 |
0.306 |
-1.602 |
MYL12B |
myosin, light chain 12B, regulatory |
18 |
3252110, 3252610, 3252716 |
U26162 |
103910 |
18p11.31 |
Hs.190086 Hs.464472 |
7 |
motor activity calcium ion binding myosin complex apical part of cell |
Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton |
216480_x_at |
MLLT10 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
10 |
21863107, 21863579 |
AF060927 |
8028 |
10p12 |
Hs.30385 |
19 |
transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding |
|
237565_at |
GCC2 |
GRIP and coiled-coil domain containing 2 |
2 |
108432008, 108432067 |
AI651345 |
9648 |
2q12.3 |
Hs.436505 Hs.469630 |
19 |
cytoplasm Golgi apparatus membrane identical protein binding |
|
209304_x_at |
GADD45B |
growth arrest and DNA-damage-inducible, beta |
19 |
2427134 |
AF087853 |
4616 |
19p13.3 |
Hs.110571 |
33 |
activation of MAPKKK activity activation of MAPKK activity protein binding negative regulation of protein kinase activity apoptosis response to stress multicellular organismal development cell differentiation regulation of cell cycle |
MAPK signaling pathway Cell cycle p53 signaling pathway |
227456_s_at |
C6orf136 |
chromosome 6 open reading frame 136 |
6 |
30722794, 2063373, 1861669 |
BF224092 |
221545 |
6p21.33 |
Hs.591787 |
7 |
|
|
229596_at |
-0.539 |
3.961 |
-2.782 |
1.382e-02 |
0.441 |
-2.830 |
AMDHD1 |
amidohydrolase domain containing 1 |
12 |
94861201 |
AW271617 |
144193 |
12q23.1 |
Hs.424907 |
4 |
iron ion binding cytoplasm cytosol histidine metabolic process zinc ion binding histidine catabolic process to glutamate and formamide metal ion binding imidazolonepropionase activity |
Histidine metabolism Metabolic pathways |
225766_s_at |
TNPO1 |
transportin 1 |
5 |
72148173, 72179685 |
AA527296 |
3842 |
5q13.2 |
Hs.482497 |
58 |
protein import into nucleus, docking protein import into nucleus, translocation protein binding nucleus nuclear pore cytoplasm nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
228163_at |
ST6GALNAC4 |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
9 |
-129709985 |
BE858453 |
27090 |
9q34 |
Hs.3972 Hs.709827 |
13 |
soluble fraction nucleus Golgi apparatus protein amino acid glycosylation glycolipid metabolic process membrane integral to membrane integral to Golgi membrane (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity |
Glycosphingolipid biosynthesis - ganglio series Metabolic pathways |
228696_at |
SLC45A3 |
solute carrier family 45, member 3 |
1 |
-203893603 |
AA631143 |
85414 |
1q32.1 |
Hs.278695 |
9 |
transport membrane integral to membrane |
|
209476_at |
TMX1 |
thioredoxin-related transmembrane protein 1 |
14 |
50776635 |
AL080080 |
81542 |
14q22.1 |
Hs.125221 |
10 |
membrane fraction nucleus endoplasmic reticulum endoplasmic reticulum membrane DNA replication transport ER to Golgi vesicle-mediated transport anti-apoptosis response to stress signal transduction cell proliferation disulfide oxidoreductase activity membrane integral to membrane electron transport chain arsenate reductase (thioredoxin) activity leukocyte activation cell redox homeostasis positive regulation of transcription, DNA-dependent positive regulation of growth |
|
225855_at |
EPB41L5 |
erythrocyte membrane protein band 4.1 like 5 |
2 |
120487138 |
AB046768 |
57669 |
2q14.2 |
Hs.654802 |
5 |
binding cytoplasm cytoskeleton adherens junction cytoskeletal protein binding extrinsic to membrane cell junction |
|
239317_at |
CEACAM21 |
carcinoembryonic antigen-related cell adhesion molecule 21 |
19 |
46774370 |
BG484601 |
90273 |
19q13.2 |
Hs.655885 |
3 |
membrane integral to membrane |
|
202515_at |
DLG1 |
discs, large homolog 1 (Drosophila) |
3 |
-198253827 |
BG251175 |
1739 |
3q29 |
Hs.292549 |
95 |
endothelial cell proliferation guanylate kinase activity phosphoprotein phosphatase activity endoplasmic reticulum endoplasmic reticulum membrane cell-cell junction actin filament organization establishment or maintenance of cell polarity protein C-terminus binding cytoskeletal protein binding postsynaptic density potassium channel regulator activity basolateral plasma membrane cell-cell adhesion protein kinase binding phosphatase binding cortical actin cytoskeleton organization G1/S transition checkpoint sarcolemma interspecies interaction between organisms synapse postsynaptic membrane negative regulation of mitotic cell cycle |
T cell receptor signaling pathway |
225008_at |
ASPH |
aspartate beta-hydroxylase |
8 |
-62739837, -62699648, -62699648, -62575669 |
AW469351 |
444 |
8q12.1 |
Hs.591874 |
24 |
peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis |
|
238987_at |
B4GALT1 |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
9 |
-33100638 |
AL574435 |
2683 |
9p13 |
Hs.272011 |
41 |
Golgi trans cisterna epithelial cell development acute inflammatory response beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity N-acetyllactosamine synthase activity lactose synthase activity extracellular region Golgi apparatus plasma membrane carbohydrate metabolic process lactose biosynthetic process galactose metabolic process protein amino acid terminal N-glycosylation cell adhesion binding of sperm to zona pellucida penetration of zona pellucida cytoskeletal protein binding negative regulation of cell proliferation glycoprotein biosynthetic process oligosaccharide biosynthetic process oligosaccharide biosynthetic process external side of plasma membrane integral to membrane basolateral plasma membrane transferase activity, transferring glycosyl groups desmosome glycocalyx manganese ion binding extracellular matrix organization mammary gland development brush border membrane development of secondary sexual characteristics metal ion binding branching morphogenesis of a tube leukocyte migration regulation of cell motion regulation of acrosome reaction positive regulation of epithelial cell proliferation involved in wound healing angiogenesis involved in wound healing positive regulation of apoptosis involved in mammary gland involution |
Galactose metabolism N-Glycan biosynthesis Keratan sulfate biosynthesis Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
219839_x_at |
-0.268 |
4.571 |
-2.884 |
1.123e-02 |
0.426 |
-2.655 |
TCL6 |
T-cell leukemia/lymphoma 6 |
14 |
95187267, 95187267, 95199345, 95199345, 95199345 |
NM_012468 |
27004 |
14q32.1 |
Hs.510368 |
4 |
molecular_function cellular_component biological_process |
|
229435_at |
0.558 |
3.363 |
3.545 |
2.885e-03 |
0.297 |
-1.499 |
GLIS3 |
GLIS family zinc finger 3 |
9 |
-3814127, -3814127 |
AW025602 |
169792 |
9p24.2 |
Hs.162125 Hs.644570 |
8 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular zinc ion binding nuclear part regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding |
|
227137_at |
-0.287 |
3.105 |
-2.236 |
4.076e-02 |
0.570 |
-3.736 |
C10orf46 |
chromosome 10 open reading frame 46 |
10 |
-120430483 |
N25937 |
143384 |
10q26.11 |
Hs.719193 |
4 |
ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding |
|
211466_at |
NFIB |
nuclear factor I/B |
9 |
-14071846 |
U70862 |
4781 |
9p24.1 |
Hs.644095 |
13 |
transcription factor activity intracellular nucleus nucleolus DNA replication regulation of transcription, DNA-dependent |
|
209194_at |
CETN2 |
centrin, EF-hand protein, 2 |
X |
-151746526 |
BC005334 |
1069 |
Xq28 |
Hs.82794 |
34 |
calcium ion binding protein binding intracellular centriole microtubule basal body cell cycle mitosis centriole replication G-protein beta/gamma-subunit binding photoreceptor connecting cilium regulation of cytokinesis cell division |
Nucleotide excision repair |
202907_s_at |
NBN |
nibrin |
8 |
-91014739 |
NM_002485 |
4683 |
8q21 |
Hs.492208 |
222 |
DNA damage checkpoint telomere maintenance nuclear chromosome, telomeric region in utero embryonic development blastocyst growth damaged DNA binding intracellular nucleus nucleoplasm replication fork chromosome nucleolus Golgi apparatus double-strand break repair response to DNA damage stimulus cell cycle cell cycle arrest mitotic cell cycle G2/M transition DNA damage checkpoint meiosis transcription factor binding cell proliferation regulation of DNA replication initiation DNA damage response, signal transduction by p53 class mediator Mre11 complex G1/S transition checkpoint nuclear inclusion body isotype switching protein N-terminus binding regulation of fibroblast proliferation neuromuscular process controlling balance |
Homologous recombination |
202939_at |
ZMPSTE24 |
zinc metallopeptidase (STE24 homolog, S. cerevisiae) |
1 |
40496319 |
NM_005857 |
10269 |
1p34 |
Hs.132642 Hs.591501 |
22 |
metalloendopeptidase activity cytoplasm endoplasmic reticulum Golgi apparatus proteolysis peptidase activity metalloexopeptidase activity zinc ion binding membrane integral to membrane metal ion binding |
|
235222_x_at |
XIAP |
X-linked inhibitor of apoptosis |
X |
122821728 |
AW675725 |
331 |
Xq25 |
Hs.356076 |
170 |
protein binding intracellular cytoplasm cytosol cytosol apoptosis anti-apoptosis zinc ion binding ligase activity modification-dependent protein catabolic process peptidase inhibitor activity caspase inhibitor activity metal ion binding |
Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer |
228480_at |
VAPA |
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa |
18 |
9903954 |
AW296039 |
9218 |
18p11.22 |
Hs.699980 |
18 |
signal transducer activity structural molecule activity protein binding membrane fraction endoplasmic reticulum microtubule plasma membrane tight junction membrane fusion integral to membrane vesicle positive regulation of I-kappaB kinase/NF-kappaB cascade protein heterodimerization activity perinuclear region of cytoplasm |
Tight junction |
209397_at |
0.514 |
8.992 |
2.775 |
1.403e-02 |
0.443 |
-2.843 |
ME2 |
malic enzyme 2, NAD(+)-dependent, mitochondrial |
18 |
46659432 |
BC000147 |
4200 |
18q21 6p25-p24 |
Hs.233119 |
24 |
malate dehydrogenase (decarboxylating) activity binding mitochondrion mitochondrial matrix malate metabolic process electron carrier activity oxidoreductase activity malate dehydrogenase (oxaloacetate-decarboxylating) activity metal ion binding NAD or NADH binding oxidation reduction |
Pyruvate metabolism Biosynthesis of phenylpropanoids Biosynthesis of alkaloids derived from terpenoid and polyketide |
206776_x_at |
-0.186 |
3.178 |
-2.140 |
4.895e-02 |
0.590 |
-3.886 |
ACRV1 |
acrosomal vesicle protein 1 |
11 |
-125047438 |
NM_001612 |
56 |
11q23-q24 |
Hs.169222 Hs.596575 |
12 |
acrosomal vesicle multicellular organismal development |
|
217315_s_at |
KLK13 |
kallikrein-related peptidase 13 |
19 |
-56251274 |
AL050220 |
26085 |
19q13.3-q13.4 |
Hs.165296 |
18 |
serine-type endopeptidase activity protein binding extracellular region cytoplasm proteolysis peptidase activity |
|
226597_at |
REEP6 |
receptor accessory protein 6 |
19 |
1442164 |
AI348159 |
92840 |
19p13.3 |
Hs.76277 |
6 |
membrane integral to membrane |
|
214719_at |
0.284 |
6.682 |
2.871 |
1.154e-02 |
0.426 |
-2.677 |
SLC46A3 |
solute carrier family 46, member 3 |
13 |
-28172219 |
AK026720 |
283537 |
13q12.3 |
Hs.117167 |
5 |
membrane integral to membrane |
|
1558027_s_at |
PRKAB2 |
protein kinase, AMP-activated, beta 2 non-catalytic subunit |
1 |
-145093308 |
AL552001 |
5565 |
1q21.1 |
Hs.50732 |
21 |
protein binding nucleoplasm cytosol cAMP-dependent protein kinase complex fatty acid biosynthetic process signal transduction protein kinase binding AMP-activated protein kinase complex regulation of fatty acid oxidation |
Insulin signaling pathway Adipocytokine signaling pathway Hypertrophic cardiomyopathy (HCM) |
228578_at |
RBM45 |
RNA binding motif protein 45 |
2 |
178685427 |
AI471723 |
129831 |
2q31.2 |
Hs.377257 |
3 |
nucleotide binding RNA binding nucleus cytoplasm multicellular organismal development nervous system development cell differentiation |
|
225851_at |
FNTB |
farnesyltransferase, CAAX box, beta |
14 |
64523259 |
BF131248 |
2342 |
14q23-q24 |
Hs.632345 |
26 |
farnesyltranstransferase activity protein farnesyltransferase activity protein binding zinc ion binding negative regulation of cell proliferation transferase activity protein amino acid farnesylation wound healing metal ion binding positive regulation of fibroblast proliferation |
|
216845_x_at |
-0.277 |
6.675 |
-3.235 |
5.465e-03 |
0.352 |
-2.042 |
MLL2 |
myeloid/lymphoid or mixed-lineage leukemia 2 |
12 |
-47699024 |
U80756 |
8085 |
12q12-q14 |
Hs.120228 |
16 |
in utero embryonic development DNA binding protein binding nucleus regulation of transcription, DNA-dependent methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity histone methyltransferase complex metal ion binding |
|
203321_s_at |
ADNP2 |
ADNP homeobox 2 |
18 |
75967902 |
AK022688 |
22850 |
18q23 |
Hs.131915 |
5 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding |
|
201916_s_at |
SEC63 |
SEC63 homolog (S. cerevisiae) |
6 |
-108295652 |
NM_007214 |
11231 |
6q21 |
Hs.26904 |
14 |
receptor activity endoplasmic reticulum protein folding protein targeting to membrane protein transport membrane integral to membrane heat shock protein binding unfolded protein binding |
|
219368_at |
NAP1L2 |
nucleosome assembly protein 1-like 2 |
X |
-72348878 |
NM_021963 |
4674 |
Xq13 |
Hs.66180 Hs.719281 |
4 |
nucleus chromatin assembly complex nucleosome assembly |
|
209991_x_at |
GABBR2 |
gamma-aminobutyric acid (GABA) B receptor, 2 |
9 |
-100090186 |
AF069755 |
9568 |
9q22.1-q22.3 |
Hs.198612 |
27 |
receptor activity G-protein coupled receptor activity GABA-B receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane signal transduction negative regulation of adenylate cyclase activity gamma-aminobutyric acid signaling pathway synaptic transmission cell junction neuron projection synapse postsynaptic membrane |
Neuroactive ligand-receptor interaction |
223391_at |
SGPP1 |
sphingosine-1-phosphate phosphatase 1 |
14 |
-63220687 |
BE880703 |
81537 |
14q23.2 |
Hs.24678 |
11 |
membrane fraction endoplasmic reticulum sphingolipid metabolic process sphinganine-1-phosphate metabolic process sphingosine metabolic process apoptosis membrane integral to membrane hydrolase activity sphingosine-1-phosphate phosphatase activity |
Sphingolipid metabolism |
214643_x_at |
BIN1 |
bridging integrator 1 |
2 |
-127522077, -127522076 |
BG034080 |
274 |
2q14 |
Hs.193163 |
69 |
protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms |
|
226784_at |
0.302 |
5.732 |
2.691 |
1.659e-02 |
0.465 |
-2.985 |
TWISTNB |
TWIST neighbor |
7 |
-19701609 |
AA121481 |
221830 |
7p21.1 |
Hs.353035 |
5 |
DNA-directed RNA polymerase activity nucleus nucleolus transcription |
|
226234_at |
0.504 |
3.807 |
4.680 |
2.854e-04 |
0.175 |
0.450 |
GDF11 |
growth differentiation factor 11 |
12 |
54423330 |
D80983 |
10220 |
12q13.2 |
Hs.600883 |
10 |
skeletal system development ureteric bud development cytokine activity protein binding extracellular region extracellular space nervous system development mesoderm development growth factor activity negative regulation of cell proliferation organ morphogenesis spinal cord anterior/posterior patterning pancreas development growth negative regulation of cell differentiation cell maturation camera-type eye morphogenesis |
|
204012_s_at |
LCMT2 |
leucine carboxyl methyltransferase 2 |
15 |
-41407265 |
AL529189 |
9836 |
15q15.3 |
Hs.200596 |
10 |
protein binding tRNA processing methyltransferase activity transferase activity |
Androgen and estrogen metabolism Histidine metabolism Tyrosine metabolism Aminophosphonate metabolism Selenoamino acid metabolism |
213098_at |
-0.217 |
5.416 |
-2.522 |
2.329e-02 |
0.507 |
-3.270 |
RQCD1 |
RCD1 required for cell differentiation1 homolog (S. pombe) |
2 |
219141921 |
AI567462 |
9125 |
2q35 |
Hs.148767 |
6 |
protein binding nucleus sex differentiation cytokine-mediated signaling pathway regulation of transcription |
RNA degradation |
230033_at |
0.464 |
4.647 |
3.411 |
3.805e-03 |
0.319 |
-1.734 |
C19orf51 |
chromosome 19 open reading frame 51 |
19 |
-60361842 |
BF436398 |
352909 |
19q13.4 |
Hs.351582 |
2 |
|
|
218496_at |
RNASEH1 |
ribonuclease H1 |
2 |
-3570565 |
BG534527 |
246243 |
2p25 |
Hs.568006 |
20 |
magnesium ion binding RNA binding endonuclease activity ribonuclease H activity ribonuclease activity cytoplasm mitochondrion RNA catabolic process hydrolase activity |
DNA replication |
215960_at |
SLC5A4 |
solute carrier family 5 (low affinity glucose cotransporter), member 4 |
22 |
-30944464 |
AJ133127 |
6527 |
22q12.2-q12.3 |
Hs.130101 |
8 |
transporter activity ion transport sodium ion transport carbohydrate transport symporter activity membrane integral to membrane sodium ion binding |
|
231741_at |
S1PR3 |
sphingosine-1-phosphate receptor 3 |
9 |
90796181 |
NM_005226 |
1903 |
9q22.1-q22.2 |
Hs.585118 |
31 |
lysosphingolipid and lysophosphatidic acid receptor activity cytokine production receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane inflammatory response signal transduction G-protein coupled receptor protein signaling pathway inhibition of adenylate cyclase activity by G-protein signaling elevation of cytosolic calcium ion concentration positive regulation of cell proliferation lipid binding anatomical structure morphogenesis regulation of interleukin-1 beta production |
Neuroactive ligand-receptor interaction |
1558034_s_at |
CP |
ceruloplasmin (ferroxidase) |
3 |
-150372979 |
AL556703 |
1356 |
3q23-q25 |
Hs.558314 |
95 |
ferroxidase activity copper ion binding extracellular region extracellular space ion transport copper ion transport cellular iron ion homeostasis aging response to nutrient oxidoreductase activity anchored to plasma membrane metal ion binding oxidation reduction |
Porphyrin and chlorophyll metabolism |
241280_at |
ALDOB |
aldolase B, fructose-bisphosphate |
9 |
-103222662 |
AV650426 |
229 |
9q21.3-q22.2 |
Hs.530274 |
40 |
fructose-bisphosphate aldolase activity microtubule organizing center glycolysis NADH oxidation cytoskeletal protein binding metabolic process lyase activity fructose 1,6-bisphosphate metabolic process positive regulation of ATPase activity centriolar satellite identical protein binding ATPase binding fructose binding vacuolar proton-transporting V-type ATPase complex assembly |
Glycolysis / Gluconeogenesis Pentose phosphate pathway Fructose and mannose metabolism Carbon fixation in photosynthetic organisms Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
201243_s_at |
0.414 |
11.157 |
2.732 |
1.528e-02 |
0.457 |
-2.915 |
ATP1B1 |
ATPase, Na+/K+ transporting, beta 1 polypeptide |
1 |
167342570 |
NM_001677 |
481 |
1q24 |
Hs.291196 |
34 |
response to hypoxia sodium:potassium-exchanging ATPase activity protein binding plasma membrane sodium:potassium-exchanging ATPase complex ATP biosynthetic process ion transport potassium ion transport sodium ion transport integral to membrane basolateral plasma membrane potassium ion binding sodium ion binding |
Cardiac muscle contraction |
226804_at |
0.328 |
4.386 |
2.476 |
2.549e-02 |
0.516 |
-3.345 |
FAM20A |
family with sequence similarity 20, member A |
17 |
-64042852, -64042852 |
AI632223 |
54757 |
17q24.2 |
Hs.268874 |
5 |
extracellular region |
|
227444_at |
ARMCX4 |
armadillo repeat containing, X-linked 4 |
X |
|
AW519141 |
158947 |
Xq22.1 |
Hs.709762 |
4 |
membrane integral to membrane |
|
213966_at |
HMG20B |
high-mobility group 20B |
19 |
3523942 |
N25429 |
10362 |
19p13.3 |
Hs.406534 |
18 |
transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle chromatin modification |
|
243508_at |
0.281 |
4.338 |
2.520 |
2.337e-02 |
0.507 |
-3.273 |
C20orf196 |
chromosome 20 open reading frame 196 |
20 |
5679042 |
AV715251 |
149840 |
20p12.3 |
Hs.529340 |
1 |
|
|
200596_s_at |
EIF3A |
eukaryotic translation initiation factor 3, subunit A |
10 |
-120784530 |
BE614908 |
8661 |
10q26 |
Hs.523299 |
38 |
formation of translation initiation complex translation initiation factor activity translation initiation factor activity structural molecule activity protein binding nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex |
|
235777_at |
ANKRD44 |
ankyrin repeat domain 44 |
2 |
-197567494 |
AI985590 |
91526 |
2q33.1 |
Hs.654819 |
6 |
protein binding |
|
230722_at |
0.407 |
5.563 |
2.333 |
3.375e-02 |
0.552 |
-3.580 |
BNC2 |
basonuclin 2 |
9 |
-16399500 |
AI377043 |
54796 |
9p22.3-p22.2 |
Hs.656581 Hs.693437 |
10 |
intracellular nucleus cytoplasm plasma membrane zinc ion binding regulation of transcription metal ion binding |
|
226208_at |
0.705 |
6.233 |
2.809 |
1.308e-02 |
0.433 |
-2.784 |
ZSWIM6 |
zinc finger, SWIM-type containing 6 |
5 |
60663856 |
AI692595 |
57688 |
5q12.1 |
Hs.650537 |
5 |
zinc ion binding metal ion binding |
|
1553265_at |
-0.268 |
3.185 |
-2.662 |
1.761e-02 |
0.473 |
-3.035 |
SLC23A3 |
solute carrier family 23 (nucleobase transporters), member 3 |
2 |
-219734426 |
NM_144712 |
151295 |
2q35 |
Hs.124565 |
5 |
transporter activity transport membrane integral to membrane |
|
223084_s_at |
CCNDBP1 |
cyclin D-type binding-protein 1 |
15 |
41264757, 41265429 |
AF246144 |
23582 |
15q14-q15 |
Hs.36794 Hs.368642 Hs.688009 |
19 |
protein binding nucleus cytoplasm cell cycle |
|
234305_s_at |
GSDMC |
gasdermin C |
8 |
-130829623 |
AJ245876 |
56169 |
8q24.1-q24.2 |
Hs.133244 |
7 |
molecular_function cytoplasm biological_process |
|
216080_s_at |
1.087 |
5.863 |
3.741 |
1.923e-03 |
0.273 |
-1.154 |
FADS3 |
fatty acid desaturase 3 |
11 |
-61397573 |
AC004770 |
3995 |
11q12-q13.1 |
Hs.21765 |
6 |
molecular_function membrane fraction endoplasmic reticulum unsaturated fatty acid biosynthetic process transport membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water heme binding electron transport chain |
|
209029_at |
0.341 |
7.786 |
2.770 |
1.415e-02 |
0.445 |
-2.850 |
COPS7A |
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) |
12 |
6703410, 6703440, 6703505, 6703709 |
AF193844 |
50813 |
12p13.31 |
Hs.530823 |
16 |
nucleus cytoplasm signalosome |
|
210044_s_at |
LYL1 |
lymphoblastic leukemia derived sequence 1 |
19 |
-13070846 |
BC002796 |
4066 |
19p13.2 |
Hs.46446 |
15 |
DNA binding nucleus transcription regulator activity regulation of transcription |
|
208203_x_at |
-0.357 |
5.783 |
-4.003 |
1.124e-03 |
0.229 |
-0.699 |
KIR2DS5 |
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 |
19 |
240800 |
NM_014513 |
3810 |
19q13.4 |
Hs.714920 |
48 |
receptor activity plasma membrane integral to plasma membrane immune response HLA-C specific inhibitory MHC class I receptor activity |
Antigen processing and presentation Natural killer cell mediated cytotoxicity |
213119_at |
0.593 |
6.281 |
2.465 |
2.607e-02 |
0.518 |
-3.364 |
SLC36A1 |
solute carrier family 36 (proton/amino acid symporter), member 1 |
5 |
150807355 |
AW058600 |
206358 |
5q33.1 |
Hs.269004 |
19 |
hydrogen:amino acid symporter activity lysosome endoplasmic reticulum plasma membrane transport amino acid transport hydrogen ion transmembrane transporter activity L-alanine transmembrane transporter activity glycine transmembrane transporter activity L-proline transmembrane transporter activity symporter activity L-alanine transport glycine transport proline transport proton transport integral to membrane |
|
200991_s_at |
0.548 |
7.593 |
3.005 |
8.771e-03 |
0.394 |
-2.445 |
SNX17 |
sorting nexin 17 |
2 |
27446892 |
NM_014748 |
9784 |
2p23-p22 |
Hs.278569 |
18 |
receptor binding cytoplasm early endosome Golgi apparatus cholesterol catabolic process intracellular protein transport receptor-mediated endocytosis signal transduction protein C-terminus binding membrane endosome transport regulation of endocytosis phosphoinositide binding low-density lipoprotein receptor binding |
|
209732_at |
0.812 |
7.902 |
2.462 |
2.619e-02 |
0.520 |
-3.368 |
CLEC2B |
C-type lectin domain family 2, member B |
12 |
-9896234 |
BC005254 |
9976 |
12p13-p12 |
Hs.85201 |
10 |
binding sugar binding integral to plasma membrane membrane |
|
207327_at |
0.270 |
5.525 |
2.347 |
3.288e-02 |
0.550 |
-3.558 |
EYA4 |
eyes absent homolog 4 (Drosophila) |
6 |
133604187 |
NM_004100 |
2070 |
6q23 |
Hs.596680 |
15 |
magnesium ion binding protein tyrosine phosphatase activity nucleus cytoplasm DNA repair response to DNA damage stimulus multicellular organismal development visual perception metabolic process anatomical structure morphogenesis chromatin modification hydrolase activity regulation of transcription |
|
227627_at |
SGK3 |
serum/glucocorticoid regulated kinase family, member 3 |
8 |
67787444, 67850015 |
AV690866 |
23678 |
8q12.3-q13.1 |
Hs.613417 |
30 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding early endosome protein amino acid phosphorylation response to stress cell communication transferase activity cytoplasmic vesicle phosphoinositide binding |
|
218241_at |
GOLGA5 |
golgi autoantigen, golgin subfamily a, 5 |
14 |
92330402 |
NM_005113 |
9950 |
14q32.12-q32.13 |
Hs.104320 |
14 |
Golgi membrane protein tyrosine kinase activity protein binding ATP binding Golgi apparatus cis-Golgi network protein amino acid phosphorylation Golgi organization membrane integral to membrane Rab GTPase binding Golgi cisterna protein homodimerization activity Golgi vesicle transport |
|
1559731_x_at |
-0.353 |
5.544 |
-2.982 |
9.192e-03 |
0.400 |
-2.485 |
MACROD1 |
MACRO domain containing 1 |
11 |
-63522606 |
AL833017 |
28992 |
11q11 |
Hs.602898 |
12 |
mitochondrion |
|
203256_at |
-0.354 |
5.599 |
-2.638 |
1.848e-02 |
0.484 |
-3.076 |
CDH3 |
cadherin 3, type 1, P-cadherin (placental) |
16 |
67235651 |
NM_001793 |
1001 |
16q22.1 |
Hs.191842 |
56 |
calcium ion binding protein binding plasma membrane cell-cell adherens junction homophilic cell adhesion visual perception integral to membrane response to stimulus |
Cell adhesion molecules (CAMs) |
1565554_at |
LOC127841 |
hypothetical protein LOC127841 |
1 |
-202604180 |
BC015457 |
127841 |
1q32.1 |
Hs.213144 |
1 |
|
|
222220_s_at |
TSNAXIP1 |
translin-associated factor X interacting protein 1 |
16 |
66398510 |
AK027245 |
55815 |
16q22.1 |
Hs.632212 |
3 |
cytoplasm multicellular organismal development spermatogenesis cell differentiation perinuclear region of cytoplasm |
|
209216_at |
WDR45 |
WD repeat domain 45 |
X |
-48819035, -48819035 |
BC000464 |
11152 |
Xp11.23 |
Hs.632807 |
8 |
|
|
235692_at |
SH3KBP1 |
SH3-domain kinase binding protein 1 |
X |
-19462003, -19462003 |
AW024527 |
30011 |
Xp22.1-p21.3 |
Hs.719268 |
58 |
molecular_function protein binding nucleus nucleolus cytoplasm cytosol cytoskeleton plasma membrane focal adhesion endocytosis apoptosis cell-cell signaling SH3 domain binding synaptosome cell junction cytoplasmic vesicle synapse |
Endocytosis |
228204_at |
0.355 |
6.514 |
2.156 |
4.750e-02 |
0.585 |
-3.862 |
PSMB4 |
proteasome (prosome, macropain) subunit, beta type, 4 |
1 |
149638664 |
AA630330 |
5692 |
1q21 |
Hs.89545 |
46 |
threonine-type endopeptidase activity nucleus cytoplasm centrosome cytosol proteasome core complex cytoskeleton peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
227055_at |
1.201 |
6.216 |
3.352 |
4.296e-03 |
0.328 |
-1.838 |
METTL7B |
methyltransferase like 7B |
12 |
54361596 |
AI827972 |
196410 |
12q13.2 |
Hs.51483 |
3 |
metabolic process methyltransferase activity transferase activity |
|
222908_at |
FAM38B |
family with sequence similarity 38, member B |
18 |
-10660859 |
AW269818 |
63895 |
18p11.22 |
Hs.585839 |
1 |
membrane integral to membrane |
|
220579_at |
-0.323 |
4.036 |
-2.779 |
1.389e-02 |
0.442 |
-2.834 |
FLJ14100 |
hypothetical protein FLJ14100 |
1 |
|
NM_025025 |
80093 |
1p36.33 |
Hs.711221 |
1 |
|
|
236703_at |
NT5C2 |
5'-nucleotidase, cytosolic II |
10 |
-104835929 |
BF114733 |
22978 |
10q24.32-q24.33 |
Hs.97439 |
12 |
nucleotide binding magnesium ion binding protein binding cytoplasm cytosol 5'-nucleotidase activity 5'-nucleotidase activity nucleotide metabolic process hydrolase activity |
Purine metabolism Pyrimidine metabolism Nicotinate and nicotinamide metabolism Biosynthesis of alkaloids derived from histidine and purine Metabolic pathways |
222868_s_at |
IL18BP |
interleukin 18 binding protein |
11 |
71387605, 71387756, 71388310, 71388620 |
AI521549 |
10068 |
11q13 |
Hs.591967 |
22 |
extracellular region interleukin-18 binding T-helper 1 type immune response receptor antagonist activity |
|
218583_s_at |
DCUN1D1 |
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) |
3 |
-184143252 |
NM_020640 |
54165 |
3q26.3 |
Hs.715661 |
16 |
molecular_function cellular_component biological_process modification-dependent protein catabolic process |
|
200938_s_at |
RERE |
arginine-glutamic acid dipeptide (RE) repeats |
1 |
-8335050, -8335050 |
AI920976 |
473 |
1p36.2-p36.1 |
Hs.463041 |
17 |
histone deacetylase complex transcription factor activity nucleus chromatin remodeling regulation of transcription, DNA-dependent NLS-bearing substrate import into nucleus multicellular organismal development poly-glutamine tract binding zinc ion binding sequence-specific DNA binding metal ion binding |
|
1555154_a_at |
QKI |
quaking homolog, KH domain RNA binding (mouse) |
6 |
163755664, 163755664 |
AF142421 |
9444 |
6q26 6q26-q27 |
Hs.510324 Hs.593520 |
23 |
RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport |
|
229805_at |
-0.231 |
5.187 |
-2.233 |
4.096e-02 |
0.571 |
-3.740 |
ZDHHC22 |
zinc finger, DHHC-type containing 22 |
14 |
-76667365 |
AI363193 |
283576 |
14q24.3 |
Hs.525485 |
5 |
zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding |
|
210759_s_at |
0.331 |
9.928 |
3.464 |
3.407e-03 |
0.308 |
-1.640 |
PSMA1 |
proteasome (prosome, macropain) subunit, alpha type, 1 |
11 |
-14492087, -14482998, -14482998 |
M64992 |
5682 |
11p15.1 |
Hs.102798 Hs.445711 |
52 |
RNA binding threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex polysome ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
225379_at |
0.291 |
8.104 |
2.180 |
4.536e-02 |
0.581 |
-3.824 |
MAPT |
microtubule-associated protein tau |
17 |
41327543 |
AA199717 |
4137 |
17q21.1 |
Hs.101174 |
545 |
microtubule cytoskeleton organization microtubule cytoskeleton organization structural constituent of cytoskeleton cytoplasm cytosol cytoskeleton microtubule microtubule associated complex plasma membrane plasma membrane negative regulation of microtubule depolymerization microtubule binding microtubule binding lipoprotein binding SH3 domain binding enzyme binding axon axon growth cone growth cone positive regulation of microtubule polymerization positive regulation of microtubule polymerization apolipoprotein E binding identical protein binding cell projection tubulin complex tubulin complex positive regulation of axon extension positive regulation of axon extension generation of neurons |
MAPK signaling pathway Alzheimer's disease |
203739_at |
ZNF217 |
zinc finger protein 217 |
20 |
-51617016 |
NM_006526 |
7764 |
20q13.2 |
Hs.155040 Hs.711564 |
18 |
transcription factor activity intracellular nucleus transcription, DNA-dependent zinc ion binding regulation of transcription metal ion binding |
|
222960_at |
CACNA1H |
calcium channel, voltage-dependent, T type, alpha 1H subunit |
16 |
1143241 |
AF175522 |
8912 |
16p13.3 |
Hs.459642 |
44 |
voltage-gated ion channel activity calcium ion binding voltage-gated calcium channel complex ion transport calcium ion transport muscle contraction muscle organ development myoblast fusion regulation of heart contraction low voltage-gated calcium channel activity membrane integral to membrane |
MAPK signaling pathway Calcium signaling pathway |
211002_s_at |
TRIM29 |
tripartite motif-containing 29 |
11 |
-119487203 |
AF230389 |
23650 |
11q22-q23 |
Hs.504115 |
20 |
transcription factor activity protein binding intracellular cytoplasm transcription from RNA polymerase II promoter zinc ion binding metal ion binding |
|
234598_at |
DKFZp564H213 |
hypothetical gene supported by AL049275 |
17 |
|
AL049275 |
440432 |
17q12 |
Hs.302051 |
1 |
|
|
1557821_at |
-0.191 |
3.139 |
-2.433 |
2.776e-02 |
0.527 |
-3.417 |
LOC283547 |
hypothetical protein LOC283547 |
14 |
|
BC035119 |
283547 |
14q21.1 |
Hs.675941 |
1 |
|
|
227888_at |
RRBP1 |
ribosome binding protein 1 homolog 180kDa (dog) |
20 |
-17542322 |
AA534989 |
6238 |
20p12 |
Hs.472213 |
19 |
receptor activity endoplasmic reticulum ribosome translation signal transduction protein transport membrane integral to membrane integral to endoplasmic reticulum membrane intracellular protein transmembrane transport |
|
230721_at |
-0.272 |
5.654 |
-2.255 |
3.930e-02 |
0.567 |
-3.706 |
C16orf52 |
chromosome 16 open reading frame 52 |
16 |
21927030 |
BF436957 |
730094 |
16p12.2 |
Hs.498890 |
3 |
|
|
203687_at |
CX3CL1 |
chemokine (C-X3-C motif) ligand 1 |
16 |
55963914 |
NM_002996 |
6376 |
16q13 |
Hs.531668 |
100 |
extracellular region extracellular space plasma membrane chemotaxis defense response immune response cell adhesion chemokine activity cell surface integral to membrane cytokine-mediated signaling pathway leukocyte chemotaxis positive regulation of inflammatory response leukocyte adhesive activation positive regulation of calcium-independent cell-cell adhesion |
Cytokine-cytokine receptor interaction Chemokine signaling pathway |
232046_at |
0.452 |
6.432 |
2.898 |
1.092e-02 |
0.423 |
-2.631 |
KIAA1217 |
KIAA1217 |
10 |
24023680, 24537725 |
AU148164 |
56243 |
10p12.2-p12.1 |
Hs.445885 |
5 |
molecular_function cytoplasm multicellular organismal development embryonic skeletal system development |
|
207064_s_at |
-0.261 |
4.253 |
-2.338 |
3.342e-02 |
0.552 |
-3.571 |
AOC2 |
amine oxidase, copper containing 2 (retina-specific) |
17 |
38250134 |
NM_009590 |
314 |
17q21 |
Hs.143102 |
5 |
copper ion binding calcium ion binding catecholamine metabolic process visual perception amine oxidase activity electron carrier activity amine metabolic process oxidoreductase activity quinone binding oxidation reduction |
Glycine, serine and threonine metabolism Tyrosine metabolism Phenylalanine metabolism beta-Alanine metabolism Isoquinoline alkaloid biosynthesis Tropane, piperidine and pyridine alkaloid biosynthesis Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Metabolic pathways |
203069_at |
SV2A |
synaptic vesicle glycoprotein 2A |
1 |
-148141499 |
NM_014849 |
9900 |
1q21.2 |
Hs.516153 |
24 |
transporter activity cytoplasm endoplasmic reticulum neurotransmitter transport membrane integral to membrane cell junction cytoplasmic vesicle synapse |
ECM-receptor interaction |
208244_at |
-0.219 |
3.691 |
-2.345 |
3.299e-02 |
0.550 |
-3.561 |
BMP3 |
bone morphogenetic protein 3 |
4 |
82171142 |
NM_001201 |
651 |
4q21 |
Hs.387411 |
17 |
ossification cytokine activity extracellular region extracellular space cell-cell signaling multicellular organismal development growth factor activity cell differentiation positive regulation of transcription from RNA polymerase II promoter cartilage development |
|
226103_at |
NEXN |
nexilin (F actin binding protein) |
1 |
78126787 |
AF114264 |
91624 |
1p31.1 |
Hs.612385 |
6 |
cytoplasm cytoskeleton cell-substrate adherens junction cell junction regulation of cell migration actin filament binding regulation of cytoskeleton organization |
|
239144_at |
0.253 |
3.106 |
2.305 |
3.566e-02 |
0.556 |
-3.625 |
B3GAT2 |
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) |
6 |
-71627789 |
AA835648 |
135152 |
6q13 |
Hs.713609 |
9 |
Golgi apparatus galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity membrane integral to membrane carbohydrate biosynthetic process transferase activity manganese ion binding metal ion binding |
Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways |
1554067_at |
C12orf66 |
chromosome 12 open reading frame 66 |
12 |
-62872685 |
BC036246 |
144577 |
12q14.2 |
Hs.505871 |
3 |
|
|
211764_s_at |
-0.693 |
10.232 |
-2.451 |
2.679e-02 |
0.524 |
-3.387 |
UBE2D1 |
ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) |
10 |
59764744 |
BC005980 |
7321 |
10q11.2-q21 |
Hs.129683 |
54 |
nucleotide binding protein polyubiquitination ubiquitin-protein ligase activity protein binding ATP binding nucleoplasm cytosol ubiquitin-dependent protein catabolic process ligase activity BMP signaling pathway anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein ubiquitination post-translational protein modification regulation of protein metabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Ubiquitin mediated proteolysis |
239792_at |
LOC440288 |
similar to FLJ16518 protein |
15 |
|
N75594 |
440288 |
15q24.1 |
Hs.655532 |
1 |
|
|
228463_at |
FOXA3 |
forkhead box A3 |
19 |
51059357 |
R99562 |
3171 |
19q13.2-q13.4 |
Hs.36137 |
14 |
cellular glucose homeostasis transcription factor activity nucleus regulation of transcription, DNA-dependent cellular response to starvation sequence-specific DNA binding |
Maturity onset diabetes of the young |
225945_at |
0.329 |
7.628 |
2.560 |
2.159e-02 |
0.497 |
-3.206 |
ZNF655 |
zinc finger protein 655 |
7 |
98993980, 98993980, 98994383, 98994383 |
BF219240 |
79027 |
7q22.1 |
Hs.696221 |
12 |
DNA binding protein binding intracellular nucleus nucleolus cytoplasm regulation of mitotic cell cycle zinc ion binding regulation of transcription metal ion binding G1 phase |
|
203487_s_at |
ARMC8 |
armadillo repeat containing 8 |
3 |
139388837, 139388837 |
NM_015396 |
25852 |
3q22.3 |
Hs.719108 |
4 |
binding |
|
218721_s_at |
C1orf27 |
chromosome 1 open reading frame 27 |
1 |
184611623 |
NM_017847 |
54953 |
1q25 |
Hs.371210 |
6 |
zinc ion binding membrane integral to membrane oxidoreductase activity |
|
205148_s_at |
CLCN4 |
chloride channel 4 |
X |
10084984 |
AA071195 |
1183 |
Xp22.3 |
Hs.495674 |
17 |
nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding |
|
204027_s_at |
0.320 |
6.365 |
2.746 |
1.487e-02 |
0.453 |
-2.892 |
METTL1 |
methyltransferase like 1 |
12 |
-56448617 |
NM_005371 |
4234 |
12q13 |
Hs.42957 |
10 |
tRNA binding protein binding nucleus tRNA modification methyltransferase activity tRNA (guanine-N7-)-methyltransferase activity transferase activity |
|
225785_at |
REEP3 |
receptor accessory protein 3 |
10 |
64951128 |
BG112359 |
221035 |
10q21.3 |
Hs.499833 |
7 |
membrane integral to membrane |
|
210538_s_at |
-0.363 |
3.460 |
-2.240 |
4.043e-02 |
0.570 |
-3.729 |
BIRC3 |
baculoviral IAP repeat-containing 3 |
11 |
101693403 |
U37546 |
330 |
11q22 |
Hs.127799 |
92 |
ubiquitin-protein ligase activity protein binding intracellular nucleus cytoplasm anti-apoptosis cell surface receptor linked signal transduction zinc ion binding regulation of apoptosis metal ion binding |
Ubiquitin mediated proteolysis Apoptosis Focal adhesion Pathways in cancer Small cell lung cancer |
208853_s_at |
CANX |
calnexin |
5 |
179058535 |
L18887 |
821 |
5q35 |
Hs.699155 |
90 |
calcium ion binding sugar binding endoplasmic reticulum protein folding protein secretion membrane integral to membrane melanosome unfolded protein binding |
Antigen processing and presentation |
234029_at |
PCDHGB8P |
protocadherin gamma subfamily B, 8 pseudogene |
5 |
140786036 |
AF152529 |
56120 |
5q31 |
Hs.672506 |
5 |
|
|
221030_s_at |
ARHGAP24 |
Rho GTPase activating protein 24 |
4 |
86615307, 86918874, 87070449 |
NM_031305 |
83478 |
4q21.23-q21.3 |
Hs.444229 |
14 |
angiogenesis GTPase activator activity protein binding intracellular cytoplasm cytoskeleton adherens junction focal adhesion signal transduction multicellular organismal development cell junction cell differentiation cell projection |
|
212771_at |
0.933 |
6.405 |
3.810 |
1.671e-03 |
0.263 |
-1.035 |
FAM171A1 |
family with sequence similarity 171, member A1 |
10 |
-15293649 |
AU150943 |
221061 |
10p13 |
Hs.66762 |
4 |
membrane integral to membrane |
|
204042_at |
WASF3 |
WAS protein family, member 3 |
13 |
26029839 |
AB020707 |
10810 |
13q12 |
Hs.635221 |
19 |
actin binding cytoplasm cytoskeleton protein complex assembly actin filament polymerization |
Adherens junction Fc gamma R-mediated phagocytosis |
219196_at |
SCG3 |
secretogranin III |
15 |
49760841 |
NM_013243 |
29106 |
15q21 |
Hs.232618 |
16 |
extracellular region |
|
241957_x_at |
LIN7B |
lin-7 homolog B (C. elegans) |
19 |
54309429 |
AI686521 |
64130 |
19q13.3 |
Hs.221737 |
15 |
protein binding plasma membrane tight junction exocytosis neurotransmitter secretion protein transport synaptosome cell junction synapse postsynaptic membrane |
|
226055_at |
ARRDC2 |
arrestin domain containing 2 |
19 |
17972943, 17979976 |
AK000689 |
27106 |
19p13.11 |
Hs.515249 |
6 |
|
|
232267_at |
0.564 |
5.050 |
3.257 |
5.227e-03 |
0.348 |
-2.004 |
GPR133 |
G protein-coupled receptor 133 |
12 |
130004404 |
AL162032 |
283383 |
12q24.33 |
Hs.719239 |
7 |
G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane |
|
234035_at |
HNRNPM |
heterogeneous nuclear ribonucleoprotein M |
19 |
8415802 |
AK022050 |
4670 |
19p13.3-p13.2 |
Hs.465808 Hs.666214 |
28 |
nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding nucleus spliceosomal complex nucleolus integral to plasma membrane RNA splicing protein domain specific binding |
|
212787_at |
YLPM1 |
YLP motif containing 1 |
14 |
74299821 |
AI952986 |
56252 |
14q24.3 |
Hs.531111 |
11 |
molecular_function cellular_component nucleus biological_process nuclear speck |
|
218677_at |
S100A14 |
S100 calcium binding protein A14 |
1 |
-151853355 |
NM_020672 |
57402 |
1q21.3 |
Hs.288998 |
7 |
calcium ion binding cytoplasm |
|
208779_x_at |
0.654 |
6.380 |
2.539 |
2.250e-02 |
0.500 |
-3.241 |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
6 |
30959839, 30960305, 30964443, 2300465, 2300931, 2305069, 2098794, 2099260, 2103398 |
L20817 |
780 |
6p21.3 |
Hs.631988 |
60 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding extracellular region integral to plasma membrane protein amino acid phosphorylation cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity |
|
201266_at |
TXNRD1 |
thioredoxin reductase 1 |
12 |
103133688, 103204856 |
NM_003330 |
7296 |
12q23-q24.1 |
Hs.708065 |
60 |
thioredoxin-disulfide reductase activity thioredoxin-disulfide reductase activity nucleus cytoplasm cytosol transport signal transduction selenium binding electron carrier activity protein disulfide oxidoreductase activity oxidoreductase activity electron transport chain cell redox homeostasis FAD binding NADP or NADPH binding |
Pyrimidine metabolism |
1568877_a_at |
ACBD5 |
acyl-Coenzyme A binding domain containing 5 |
10 |
-27524149, -27524149 |
BC025309 |
91452 |
10p12.1 |
Hs.530597 |
4 |
acyl-CoA binding transport lipid binding membrane integral to membrane |
|
210418_s_at |
IDH3B |
isocitrate dehydrogenase 3 (NAD+) beta |
20 |
-2587040 |
AF023265 |
3420 |
20p13 |
Hs.436405 |
14 |
magnesium ion binding isocitrate dehydrogenase (NAD+) activity mitochondrion mitochondrial matrix tricarboxylic acid cycle isocitrate metabolic process visual perception electron carrier activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding response to stimulus NAD or NADH binding oxidation reduction |
Citrate cycle (TCA cycle) Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
223615_at |
-0.295 |
6.230 |
-2.731 |
1.532e-02 |
0.457 |
-2.917 |
ABI3 |
ABI family, member 3 |
17 |
44642587 |
AL136709 |
51225 |
17q21.3 |
Hs.130719 |
12 |
protein binding intracellular cytoplasm cell motion peptidyl-tyrosine phosphorylation lamellipodium regulation of cell migration |
|
228490_at |
0.518 |
3.485 |
2.773 |
1.408e-02 |
0.444 |
-2.846 |
ABHD2 |
abhydrolase domain containing 2 |
15 |
87432384 |
AW292816 |
11057 |
15q26.1 |
Hs.122337 Hs.705984 |
10 |
molecular_function carboxylesterase activity biological_process response to wounding membrane integral to membrane hydrolase activity negative regulation of cell migration |
|
210605_s_at |
0.424 |
6.486 |
3.792 |
1.733e-03 |
0.267 |
-1.066 |
MFGE8 |
milk fat globule-EGF factor 8 protein |
15 |
-87242917 |
BC003610 |
4240 |
15q25 |
Hs.3745 |
36 |
phosphatidylserine binding integrin binding protein binding extracellular space cytoplasm phagocytosis, recognition phagocytosis, engulfment cell adhesion single fertilization phosphatidylethanolamine binding external side of plasma membrane membrane extrinsic to plasma membrane interspecies interaction between organisms positive regulation of phagocytosis |
|
1563632_at |
LOC220980 |
hypothetical protein LOC220980 |
10 |
|
AK056518 |
220980 |
10q11.21 |
Hs.645270 |
1 |
|
|
205541_s_at |
0.573 |
6.321 |
2.472 |
2.572e-02 |
0.517 |
-3.353 |
GSPT2 |
G1 to S phase transition 2 |
X |
51503236 |
NM_018094 |
23708 |
Xp11.22 |
Hs.59523 |
10 |
nucleotide binding translation release factor activity GTPase activity protein binding protein binding GTP binding cytoplasm translation cell cycle |
|
823_at |
CX3CL1 |
chemokine (C-X3-C motif) ligand 1 |
16 |
55963914 |
U84487 |
6376 |
16q13 |
Hs.531668 |
100 |
extracellular region extracellular space plasma membrane chemotaxis defense response immune response cell adhesion chemokine activity cell surface integral to membrane cytokine-mediated signaling pathway leukocyte chemotaxis positive regulation of inflammatory response leukocyte adhesive activation positive regulation of calcium-independent cell-cell adhesion |
Cytokine-cytokine receptor interaction Chemokine signaling pathway |
211136_s_at |
0.249 |
5.855 |
2.785 |
1.372e-02 |
0.440 |
-2.824 |
CLPTM1 |
cleft lip and palate associated transmembrane protein 1 |
19 |
50150477 |
BC004865 |
1209 |
19q13.2-q13.3 |
Hs.444441 |
12 |
integral to plasma membrane multicellular organismal development external side of plasma membrane membrane cell differentiation regulation of T cell differentiation in the thymus |
|
228725_x_at |
0.510 |
6.179 |
4.440 |
4.623e-04 |
0.193 |
0.048 |
PRMT2 |
protein arginine methyltransferase 2 |
21 |
46879954 |
BF003112 |
3275 |
21q22.3 |
Hs.154163 |
17 |
signal transducer activity nucleus protein amino acid methylation signal transduction methyltransferase activity transferase activity identical protein binding |
|
217976_s_at |
0.360 |
7.682 |
2.348 |
3.277e-02 |
0.550 |
-3.555 |
DYNC1LI1 |
dynein, cytoplasmic 1, light intermediate chain 1 |
3 |
-32542470 |
NM_016141 |
51143 |
3p22.3 |
Hs.529495 |
11 |
nucleotide binding motor activity ATP binding microtubule dynein complex |
|
201885_s_at |
CYB5R3 |
cytochrome b5 reductase 3 |
22 |
-41344757, -41344757 |
NM_000398 |
1727 |
22q13.2-q13.31 22q13.31-qter |
Hs.700572 |
49 |
cytochrome-b5 reductase activity cytoplasm mitochondrion mitochondrial outer membrane mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane hemoglobin complex cholesterol biosynthetic process blood circulation electron carrier activity membrane oxidoreductase activity oxidation reduction |
Amino sugar and nucleotide sugar metabolism |
223212_at |
0.462 |
7.546 |
3.583 |
2.669e-03 |
0.290 |
-1.432 |
ZDHHC16 |
zinc finger, DHHC-type containing 16 |
10 |
99195919, 99195936 |
BC004535 |
84287 |
10q24.1 |
Hs.76662 |
6 |
endoplasmic reticulum apoptosis zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding |
|
232936_at |
KCNA7 |
potassium voltage-gated channel, shaker-related subfamily, member 7 |
19 |
-54262486 |
AJ310479 |
3743 |
19q13.3 |
Hs.306973 |
5 |
voltage-gated ion channel activity voltage-gated potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex membrane integral to membrane potassium ion binding |
|
221724_s_at |
CLEC4A |
C-type lectin domain family 4, member A |
12 |
8167494 |
AF200738 |
50856 |
12p13 |
Hs.504657 |
15 |
transmembrane receptor activity binding sugar binding integral to plasma membrane immune response cell adhesion cell surface receptor linked signal transduction membrane |
|
227512_at |
MEX3A |
mex-3 homolog A (C. elegans) |
1 |
-154308427 |
AW248508 |
92312 |
1q22 |
Hs.591496 |
3 |
cytoplasmic mRNA processing body RNA binding protein binding nucleus cytoplasm zinc ion binding metal ion binding |
|
229770_at |
0.709 |
6.353 |
4.134 |
8.595e-04 |
0.217 |
-0.473 |
GLT1D1 |
glycosyltransferase 1 domain containing 1 |
12 |
127904033 |
AI041543 |
144423 |
12q24.33 |
Hs.655668 |
6 |
extracellular region biosynthetic process transferase activity, transferring glycosyl groups |
|
1562903_at |
-0.655 |
4.554 |
-3.997 |
1.138e-03 |
0.230 |
-0.709 |
hCG_1990547 |
family with sequence similarity 86, member A pseudogene |
8 |
8123501, 8123501, 8123501 |
BC035792 |
286042 |
8p23.1 |
Hs.656318 |
2 |
|
|
221082_s_at |
NDRG3 |
NDRG family member 3 |
20 |
-34713582 |
NM_022477 |
57446 |
20q11.21-q11.23 |
Hs.437338 |
9 |
molecular_function cytoplasm spermatogenesis cell differentiation negative regulation of cell growth |
|
219874_at |
-0.300 |
4.129 |
-2.697 |
1.641e-02 |
0.464 |
-2.975 |
SLC12A8 |
solute carrier family 12 (potassium/chloride transporters), member 8 |
3 |
-126284169 |
NM_024628 |
84561 |
3q21.2 |
Hs.658514 |
7 |
ion transport potassium ion transport symporter activity membrane integral to membrane potassium ion binding chloride ion binding |
|
225059_at |
AGTRAP |
angiotensin II receptor-associated protein |
1 |
11718728 |
BE875567 |
57085 |
1p36.22 |
Hs.464438 |
14 |
protein binding endoplasmic reticulum Golgi apparatus membrane integral to membrane cytoplasmic vesicle |
|
223347_at |
MUM1 |
melanoma associated antigen (mutated) 1 |
19 |
1305975, 1307322 |
AL360266 |
84939 |
19p13.3 |
Hs.515016 |
6 |
|
|
206734_at |
JRKL |
jerky homolog-like (mouse) |
11 |
95762805 |
NM_003772 |
8690 |
11q21 |
Hs.105940 |
4 |
DNA binding nucleus central nervous system development regulation of transcription |
|
237765_at |
C14orf68 |
chromosome 14 open reading frame 68 |
14 |
99859431 |
AA677293 |
283600 |
14q32.2 |
Hs.108268 |
4 |
transporter activity binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
1556377_s_at |
0.688 |
5.956 |
3.675 |
2.205e-03 |
0.276 |
-1.270 |
LMO7 |
LIM domain 7 |
13 |
75092570, 75232797 |
AF174600 |
4008 |
13q22.2 |
Hs.207631 |
18 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding nucleus cytoplasm zinc ion binding protein ubiquitination metal ion binding |
Adherens junction |
208414_s_at |
HOXB3 |
homeobox B3 |
17 |
-43981230 |
NM_002146 |
3213 |
17q21.3 |
Hs.654560 |
21 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development anterior/posterior pattern formation glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding embryonic skeletal system morphogenesis cartilage development definitive hemopoiesis |
|
211447_s_at |
PDE4A |
phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) |
19 |
10392332, 10402520, 10404110, 10424632 |
U18088 |
5141 |
19p13.2 |
Hs.89901 |
32 |
3',5'-cyclic-AMP phosphodiesterase activity membrane fraction soluble fraction signal transduction membrane hydrolase activity |
Purine metabolism |
204496_at |
STRN3 |
striatin, calmodulin binding protein 3 |
14 |
-30432755 |
NM_014574 |
29966 |
14q13-q21 |
Hs.21016 Hs.401843 |
13 |
calmodulin binding membrane fraction nucleus cytoplasm cytosol cell cycle membrane |
|
203396_at |
PSMA4 |
proteasome (prosome, macropain) subunit, alpha type, 4 |
15 |
76619801 |
NM_002789 |
5685 |
15q25.1 |
Hs.251531 |
47 |
threonine-type endopeptidase activity nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process identical protein binding negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
241481_at |
FAM81A |
family with sequence similarity 81, member A |
15 |
57517663 |
BF448365 |
145773 |
15q22.2 |
Hs.659778 |
2 |
|
|
205332_at |
RCE1 |
RCE1 homolog, prenyl protein peptidase (S. cerevisiae) |
11 |
66367458 |
AF121951 |
9986 |
11q13 |
Hs.654972 |
9 |
metalloendopeptidase activity endoplasmic reticulum integral to plasma membrane proteolysis membrane hydrolase activity |
|
201087_at |
PXN |
paxillin |
12 |
-119132632, -119132632 |
NM_002859 |
5829 |
12q24.31 |
Hs.446336 |
140 |
protein binding cytoplasm cytoskeleton microtubule associated complex plasma membrane focal adhesion cell adhesion cell-matrix adhesion signal transduction signal complex assembly zinc ion binding vinculin binding lamellipodium cell junction cellular response to reactive oxygen species metal ion binding |
Chemokine signaling pathway VEGF signaling pathway Focal adhesion Leukocyte transendothelial migration Regulation of actin cytoskeleton |
226713_at |
0.376 |
6.527 |
3.509 |
3.109e-03 |
0.303 |
-1.562 |
CCDC50 |
coiled-coil domain containing 50 |
3 |
192529567 |
AI247881 |
152137 |
3q28 |
Hs.478682 |
12 |
protein binding cytoplasm |
|
1556474_a_at |
0.257 |
2.496 |
2.360 |
3.206e-02 |
0.545 |
-3.537 |
FLJ38379 |
hypothetical FLJ38379 |
2 |
|
AK095698 |
285097 |
2q37.3 |
Hs.653239 |
1 |
|
|
201416_at |
SOX4 |
SRY (sex determining region Y)-box 4 |
6 |
21701950 |
BG528420 |
6659 |
6p22.3 |
Hs.643910 |
35 |
pro-B cell differentiation transcription factor activity protein binding nucleus cytoplasm heart development positive regulation of cell proliferation positive regulation of Wnt receptor signaling pathway T cell differentiation exocrine pancreas development positive regulation of apoptosis negative regulation of apoptosis positive regulation of transcription, DNA-dependent protein stabilization Wnt receptor signaling pathway through beta-catenin |
|
218239_s_at |
GTPBP4 |
GTP binding protein 4 |
10 |
1024348 |
NM_012341 |
23560 |
10p15-p14 |
Hs.215766 |
10 |
regulation of cyclin-dependent protein kinase activity nucleotide binding GTPase activity protein binding GTP binding nucleus nucleolus cytoplasm negative regulation of DNA replication negative regulation of cell proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization |
|
228628_at |
-0.373 |
6.516 |
-2.608 |
1.960e-02 |
0.491 |
-3.125 |
SRGAP2P1 |
SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1 |
1 |
|
AI478268 |
653464 |
1p11.2 |
Hs.523529 Hs.698027 |
2 |
|
|
226327_at |
ZNF507 |
zinc finger protein 507 |
19 |
37528353 |
N64593 |
22847 |
19q13.11 |
Hs.205392 |
5 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
240486_at |
-0.263 |
4.261 |
-3.159 |
6.388e-03 |
0.364 |
-2.175 |
HELZ |
helicase with zinc finger |
17 |
-62497015 |
AA761673 |
9931 |
17q24.2 |
Hs.370140 Hs.569824 Hs.596366 |
8 |
nucleotide binding nucleic acid binding helicase activity ATP binding nucleus zinc ion binding hydrolase activity metal ion binding |
|
1554188_at |
-0.240 |
5.927 |
-2.568 |
2.122e-02 |
0.497 |
-3.192 |
C11orf53 |
chromosome 11 open reading frame 53 |
11 |
110631916 |
BC039669 |
341032 |
11q23.1 |
Hs.298685 |
3 |
|
|
225738_at |
RAPGEF1 |
Rap guanine nucleotide exchange factor (GEF) 1 |
9 |
-133441977, -133441977 |
AA761259 |
2889 |
9q34.3 |
Hs.127897 |
46 |
guanyl-nucleotide exchange factor activity protein binding intracellular endosome cytosol transmembrane receptor protein tyrosine kinase signaling pathway SH3 domain binding regulation of small GTPase mediated signal transduction |
Focal adhesion Neurotrophin signaling pathway Insulin signaling pathway Renal cell carcinoma |
225339_at |
SPAG9 |
sperm associated antigen 9 |
17 |
-46394534 |
BG290577 |
9043 |
17q21.33 |
Hs.463439 |
22 |
acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm |
|
204607_at |
HMGCS2 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) |
1 |
-120092525 |
NM_005518 |
3158 |
1p13-p12 |
Hs.59889 |
13 |
hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity mitochondrion mitochondrial inner membrane mitochondrial matrix cholesterol biosynthetic process response to nutrient metabolic process isoprenoid biosynthetic process transferase activity response to drug response to peptide hormone stimulus |
Synthesis and degradation of ketone bodies Valine, leucine and isoleucine degradation Butanoate metabolism Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways PPAR signaling pathway |
205846_at |
PTPRB |
protein tyrosine phosphatase, receptor type, B |
12 |
-69196898, -69196898 |
NM_002837 |
5787 |
12q15-q21 |
Hs.434375 |
29 |
transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation membrane hydrolase activity |
Adherens junction |
224654_at |
0.252 |
8.166 |
2.206 |
4.320e-02 |
0.577 |
-3.784 |
DDX21 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 |
10 |
70385897 |
BG164358 |
9188 |
10q21 |
Hs.223141 Hs.576875 |
18 |
nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity protein binding ATP binding nucleus nucleolus hydrolase activity |
|
1552853_at |
VWA5B1 |
von Willebrand factor A domain containing 5B1 |
1 |
20489998 |
NM_144623 |
127731 |
1p36.12 |
Hs.205178 |
3 |
extracellular region |
|
217912_at |
0.294 |
8.380 |
2.476 |
2.551e-02 |
0.516 |
-3.346 |
DUS1L |
dihydrouridine synthase 1-like (S. cerevisiae) |
17 |
-77609039 |
NM_022156 |
64118 |
17q25.3 |
Hs.514599 |
2 |
tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity FAD binding oxidation reduction |
|
205931_s_at |
CREB5 |
cAMP responsive element binding protein 5 |
7 |
28305464, 28418668, 28441758, 28692245 |
NM_004904 |
9586 |
7p15.1 |
Hs.437075 |
10 |
transcription factor activity intracellular nucleus transcription from RNA polymerase II promoter zinc ion binding sequence-specific DNA binding positive regulation of transcription, DNA-dependent metal ion binding protein dimerization activity |
Huntington's disease Prostate cancer |
218143_s_at |
SCAMP2 |
secretory carrier membrane protein 2 |
15 |
-72924249 |
NM_005697 |
10066 |
15q23-q25 |
Hs.458917 |
12 |
protein binding endosome Golgi apparatus post-Golgi vesicle-mediated transport protein transport membrane integral to membrane trans-Golgi network membrane recycling endosome membrane |
|
226734_at |
EIF4E2 |
eukaryotic translation initiation factor 4E family member 2 |
2 |
233123600 |
AW242220 |
9470 |
2q37.1 |
Hs.292026 Hs.700929 |
15 |
RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation |
mTOR signaling pathway Insulin signaling pathway |
211174_s_at |
-0.291 |
4.438 |
-2.147 |
4.835e-02 |
0.589 |
-3.876 |
CCKAR |
cholecystokinin A receptor |
4 |
-26092115 |
L13605 |
886 |
4p15.1-p15.2 |
Hs.129 |
50 |
neuron migration receptor activity G-protein coupled receptor activity cholecystokinin receptor activity plasma membrane integral to plasma membrane signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger elevation of cytosolic calcium ion concentration axonogenesis response to nutrient digestion feeding behavior forebrain development |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
224818_at |
SORT1 |
sortilin 1 |
1 |
-109653714 |
BE622952 |
6272 |
1p21.3-p13.1 |
Hs.485195 Hs.703487 |
47 |
ossification receptor activity nucleus lysosome early endosome endoplasmic reticulum microsome Golgi apparatus plasma membrane coated pit transport Golgi to endosome transport endocytosis neuropeptide signaling pathway multicellular organismal development endosome to lysosome transport induction of apoptosis by extracellular signals cell surface nerve growth factor receptor activity regulation of gene expression myotube differentiation integral to membrane cytoplasmic membrane-bounded vesicle vesicle organization enzyme binding clathrin-coated vesicle cell differentiation neurotensin receptor activity, non-G-protein coupled endosome transport via multivesicular body sorting pathway response to insulin stimulus negative regulation of apoptosis glucose import nerve growth factor receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity |
Lysosome Neurotrophin signaling pathway |
217946_s_at |
0.490 |
7.029 |
2.709 |
1.602e-02 |
0.459 |
-2.955 |
SAE1 |
SUMO1 activating enzyme subunit 1 |
19 |
52325919, 52325954, 52325971 |
NM_016402 |
10055 |
19q13.32 |
Hs.515500 |
20 |
ubiquitin activating enzyme activity nucleus protein modification process protein C-terminus binding protein C-terminus binding enzyme activator activity metabolic process protein ubiquitination ligase activity modification-dependent protein catabolic process ATP-dependent protein binding protein heterodimerization activity |
Ubiquitin mediated proteolysis |
219918_s_at |
ASPM |
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
1 |
-195319879 |
NM_018123 |
259266 |
1q31 |
Hs.121028 |
35 |
calmodulin binding nucleus cytoplasm cell cycle mitosis cell division |
|
211839_s_at |
CSF1 |
colony stimulating factor 1 (macrophage) |
1 |
110254755, 110254755, 110254755 |
U22386 |
1435 |
1p21-p13 |
Hs.591402 |
123 |
positive regulation of cell-matrix adhesion reproductive developmental process cytokine activity macrophage colony stimulating factor receptor binding extracellular region extracellular space plasma membrane positive regulation of cell proliferation positive regulation of gene expression positive regulation of foam cell differentiation integral to membrane hemopoiesis cell differentiation positive regulation of cell migration positive regulation of cellular protein metabolic process positive regulation of mononuclear cell proliferation monocyte activation protein homodimerization activity receptor complex positive regulation of monocyte differentiation positive regulation of protein kinase activity perinuclear region of cytoplasm |
Cytokine-cytokine receptor interaction Hematopoietic cell lineage |
213859_x_at |
SMARCA5 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
4 |
144654065 |
AI652586 |
8467 |
4q31.1-q31.2 |
Hs.558422 Hs.710623 |
37 |
nucleotide binding condensed chromosome DNA binding RNA polymerase II transcription factor activity helicase activity ATP binding nucleus nucleoplasm nucleolus chromatin assembly or disassembly nucleosome assembly transcription initiation regulation of transcription from RNA polymerase II promoter embryonic development transcription activator activity nucleosome positioning hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides ATPase activity RSF complex nucleosome binding histone binding ATP-dependent chromatin remodeling |
|
1555620_a_at |
-0.304 |
6.581 |
-3.539 |
2.919e-03 |
0.298 |
-1.509 |
PTGIR |
prostaglandin I2 (prostacyclin) receptor (IP) |
19 |
-51815564 |
BC017857 |
5739 |
19q13.3 |
Hs.458324 |
55 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger cell-cell signaling |
Neuroactive ligand-receptor interaction Vascular smooth muscle contraction |
223831_x_at |
ISY1 |
ISY1 splicing factor homolog (S. cerevisiae) |
3 |
-130330924 |
BC004442 |
57461 |
3q21.3 |
Hs.512661 |
7 |
nucleus spliceosomal complex nucleolus cytoplasm mRNA processing RNA splicing |
|
215695_s_at |
GYG2 |
glycogenin 2 |
X |
2756862 |
U94357 |
8908 |
Xp22.3 |
Hs.567381 Hs.701629 |
13 |
soluble fraction cytosol glycogen biosynthetic process glycogenin glucosyltransferase activity glycogenin glucosyltransferase activity transferase activity, transferring glycosyl groups |
|
206319_s_at |
SPINLW1 |
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) |
20 |
-43602678, -43602678 |
AF286368 |
57119 |
20q12-q13.2 |
Hs.121084 |
10 |
serine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity |
|
219737_s_at |
PCDH9 |
protocadherin 9 |
13 |
-65774967 |
AI524125 |
5101 |
13q14.3-q21.1 |
Hs.654709 Hs.719302 |
8 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane |
|
220545_s_at |
TSKS |
testis-specific serine kinase substrate |
19 |
-54934822 |
NM_021733 |
60385 |
19q13.3 |
Hs.515858 |
6 |
protein binding |
|
208374_s_at |
CAPZA1 |
capping protein (actin filament) muscle Z-line, alpha 1 |
1 |
112963597 |
NM_006135 |
829 |
1p13.2 |
Hs.514934 |
21 |
actin binding protein binding protein complex assembly cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping |
|
203804_s_at |
LUC7L3 |
LUC7-like 3 (S. cerevisiae) |
17 |
46151975 |
NM_006107 |
51747 |
17q21.33 |
Hs.130293 |
15 |
DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck |
|
225001_at |
RAB3D |
RAB3D, member RAS oncogene family |
19 |
-11296092 |
AI744658 |
9545 |
19p13.2 |
Hs.655274 |
13 |
nucleotide binding GTPase activity protein binding GTP binding plasma membrane exocytosis small GTPase mediated signal transduction protein transport |
|
209944_at |
ZNF410 |
zinc finger protein 410 |
14 |
73423338 |
BC000330 |
57862 |
14q24.3 |
Hs.270869 |
9 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
209405_s_at |
FAM3A |
family with sequence similarity 3, member A |
X |
-153387699 |
BC002934 |
60343 |
Xq28 |
Hs.289108 |
7 |
molecular_function extracellular region biological_process |
|
212992_at |
0.323 |
3.712 |
2.570 |
2.117e-02 |
0.497 |
-3.190 |
AHNAK2 |
AHNAK nucleoprotein 2 |
14 |
-104474635 |
AI935123 |
113146 |
14q32.33 |
Hs.441783 |
3 |
protein binding nucleus cytoplasm keratinization |
|
212846_at |
RRP1B |
ribosomal RNA processing 1 homolog B (S. cerevisiae) |
21 |
43903859 |
AA811192 |
23076 |
21q22.3 |
Hs.654727 |
14 |
protein binding nucleus nucleolus cytosol rRNA processing preribosome, small subunit precursor |
|
221931_s_at |
SEH1L |
SEH1-like (S. cerevisiae) |
18 |
12937982 |
AV701173 |
81929 |
18p11.21 |
Hs.301048 |
9 |
kinetochore nucleus nuclear pore organization mitotic metaphase plate congression protein transport Nup107-160 complex Nup107-160 complex mRNA transport attachment of spindle microtubules to kinetochore during mitosis intracellular protein transmembrane transport |
|
211803_at |
CDK2 |
cyclin-dependent kinase 2 |
12 |
54646822 |
AB012305 |
1017 |
12q13 |
Hs.19192 Hs.689624 |
306 |
G2/M transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase activity cyclin-dependent protein kinase activity ATP binding nucleus nucleoplasm cytoplasm cytosol regulation of DNA replication protein amino acid phosphorylation cell cycle mitosis traversing start control point of mitotic cell cycle positive regulation of cell proliferation transferase activity histone kinase activity identical protein binding cell division |
Cell cycle p53 signaling pathway Pathways in cancer Prostate cancer Small cell lung cancer |
220935_s_at |
0.317 |
6.696 |
2.825 |
1.266e-02 |
0.429 |
-2.756 |
CDK5RAP2 |
CDK5 regulatory subunit associated protein 2 |
9 |
-122190967 |
NM_018249 |
55755 |
9q33.2 |
Hs.269560 |
18 |
centrosome cytoskeleton brain development microtubule binding neuronal Cdc2-like kinase binding regulation of neuron differentiation |
|
212275_s_at |
SRCAP |
Snf2-related CREBBP activator protein |
16 |
30617962 |
NM_006662 |
10847 |
16p11.2 |
Hs.647334 |
16 |
nucleotide binding DNA binding transcription coactivator activity helicase activity histone acetyltransferase activity ATP binding nucleus regulation of transcription from RNA polymerase II promoter chromatin modification hydrolase activity protein complex interspecies interaction between organisms regulation of transcription |
|
213421_x_at |
-0.306 |
5.154 |
-2.896 |
1.096e-02 |
0.424 |
-2.634 |
PRSS3 |
protease, serine, 3 |
9 |
33740514, 33785558 |
AW007273 |
5646 |
9p11.2 |
Hs.654513 |
22 |
serine-type endopeptidase activity calcium ion binding protein binding extracellular region extracellular space proteolysis proteolysis digestion peptidase activity zymogen activation endothelial cell migration |
Neuroactive ligand-receptor interaction |
206277_at |
P2RY2 |
purinergic receptor P2Y, G-protein coupled, 2 |
11 |
72606991, 72607149 |
NM_002564 |
5029 |
11q13.5-q14.1 |
Hs.339 |
43 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane cellular ion homeostasis signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger purinergic nucleotide receptor activity, G-protein coupled |
Neuroactive ligand-receptor interaction |
1562299_at |
-0.236 |
3.018 |
-2.795 |
1.346e-02 |
0.437 |
-2.808 |
C14orf25 |
chromosome 14 open reading frame 25 |
14 |
|
BC038110 |
319089 |
14q21.1 |
Hs.659936 |
2 |
|
|
1560874_at |
EFCAB4B |
EF-hand calcium binding domain 4B |
12 |
-3627369, -3619818, -3594754 |
AK057608 |
84766 |
12p13.32 |
Hs.504534 Hs.719531 |
6 |
calcium ion binding |
|
228409_at |
-0.343 |
8.084 |
-2.135 |
4.939e-02 |
0.590 |
-3.894 |
PLIN4 |
perilipin 4 |
19 |
-4453191 |
T62068 |
729359 |
19p13.3 |
Hs.591387 |
4 |
cytoplasm plasma membrane monolayer-surrounded lipid storage body |
|
212814_at |
AHCYL2 |
adenosylhomocysteinase-like 2 |
7 |
128652099, 128795217 |
AB020635 |
23382 |
7q32.1 |
Hs.600789 |
5 |
adenosylhomocysteinase activity binding one-carbon metabolic process metabolic process hydrolase activity |
Cysteine and methionine metabolism Selenoamino acid metabolism Metabolic pathways |
211603_s_at |
ETV4 |
ets variant 4 |
17 |
-38960736, -38960736 |
U35622 |
2118 |
17q21 |
Hs.434059 |
48 |
transcription factor activity nucleus nucleolus regulation of transcription, DNA-dependent motor axon guidance organ morphogenesis transcription activator activity sequence-specific DNA binding positive regulation of transcription |
|
218579_s_at |
0.269 |
4.886 |
2.330 |
3.396e-02 |
0.552 |
-3.585 |
DHX35 |
DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
20 |
37024413 |
NM_021931 |
60625 |
20q11.22-q12 |
Hs.444520 |
5 |
nucleotide binding nucleic acid binding helicase activity ATP binding spliceosomal complex mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity |
|
232803_at |
FLJ31958 |
hypothetical LOC143153 |
10 |
|
H09470 |
143153 |
10q11.23 |
Hs.706372 |
1 |
|
|
210014_x_at |
IDH3B |
isocitrate dehydrogenase 3 (NAD+) beta |
20 |
-2587040 |
AF023266 |
3420 |
20p13 |
Hs.436405 |
14 |
magnesium ion binding isocitrate dehydrogenase (NAD+) activity mitochondrion mitochondrial matrix tricarboxylic acid cycle isocitrate metabolic process visual perception electron carrier activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor manganese ion binding response to stimulus NAD or NADH binding oxidation reduction |
Citrate cycle (TCA cycle) Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
218488_at |
0.177 |
9.280 |
2.218 |
4.218e-02 |
0.575 |
-3.764 |
EIF2B3 |
eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
1 |
-45089036 |
NM_020365 |
8891 |
1p34.1 |
Hs.533549 |
25 |
translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm eukaryotic translation initiation factor 2B complex translational initiation biosynthetic process response to heat response to heat response to glucose stimulus oligodendrocyte development transferase activity nucleotidyltransferase activity negative regulation of translational initiation in response to stress response to peptide hormone stimulus cellular response to stimulus |
|
217485_x_at |
PMS2L1 |
postmeiotic segregation increased 2-like 1 pseudogene |
7 |
-99756198 |
D38435 |
5379 |
7q22.1 |
Hs.634244 Hs.661055 Hs.709266 |
7 |
molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding |
|
217856_at |
0.446 |
5.399 |
2.142 |
4.873e-02 |
0.590 |
-3.883 |
RBM8A |
RNA binding motif protein 8A |
1 |
144218994 |
AF182415 |
9939 |
1q12 |
Hs.356873 |
43 |
nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear mRNA splicing, via spliceosome mRNA binding protein binding nucleus spliceosomal complex cytoplasm transport biological_process RNA splicing nuclear speck exon-exon junction complex mRNA transport |
|
214934_at |
ATP9B |
ATPase, class II, type 9B |
18 |
74930384 |
AW411030 |
374868 |
18q23 |
Hs.465475 |
6 |
nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport aminophospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances cation-transporting ATPase activity |
|
200682_s_at |
UBE2L3 |
ubiquitin-conjugating enzyme E2L 3 |
22 |
20251956 |
BG531983 |
7332 |
22q11.21 |
Hs.108104 Hs.603229 Hs.715088 |
38 |
ubiquitin ligase complex nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ligase activity enzyme binding regulation of protein metabolic process |
Ubiquitin mediated proteolysis Parkinson's disease |
224337_s_at |
FZD4 |
frizzled homolog 4 (Drosophila) |
11 |
-86334368 |
AB054881 |
8322 |
11q14.2 |
Hs.591968 |
25 |
non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity protein binding G-protein coupled receptor protein signaling pathway multicellular organismal development membrane integral to membrane Wnt receptor signaling pathway Wnt receptor activity |
Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma |
235188_at |
C14orf135 |
chromosome 14 open reading frame 135 |
14 |
59628381 |
AI479328 |
64430 |
14q23.1 |
Hs.509499 |
7 |
membrane integral to membrane |
|
224001_at |
-0.353 |
5.706 |
-2.912 |
1.061e-02 |
0.418 |
-2.607 |
FAM135B |
family with sequence similarity 135, member B |
8 |
-139211447 |
AF131744 |
51059 |
8q24.23 |
Hs.126024 |
5 |
|
|
212820_at |
DMXL2 |
Dmx-like 2 |
15 |
-49527230 |
AB020663 |
23312 |
15q21.2 |
Hs.511386 |
9 |
synaptic vesicle membrane Rab GTPase binding cell junction cytoplasmic vesicle synapse |
|
214439_x_at |
BIN1 |
bridging integrator 1 |
2 |
-127522077, -127522076 |
AF043899 |
274 |
2q14 |
Hs.193163 |
69 |
protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms |
|
226015_at |
0.359 |
6.752 |
3.504 |
3.141e-03 |
0.304 |
-1.571 |
ZNF12 |
zinc finger protein 12 |
7 |
-6694588 |
AI865669 |
7559 |
7p22.1 |
Hs.431471 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
205745_x_at |
ADAM17 |
ADAM metallopeptidase domain 17 |
2 |
-9546861 |
NM_003183 |
6868 |
2p25 |
Hs.404914 |
121 |
response to hypoxia positive regulation of protein amino acid phosphorylation neutrophil mediated immunity germinal center formation metalloendopeptidase activity interleukin-6 receptor binding integrin binding protein binding cytoplasm integral to plasma membrane cell-cell junction focal adhesion proteolysis epidermal growth factor receptor signaling pathway Notch signaling pathway peptidase activity zinc ion binding positive regulation of cell proliferation response to bacterium cell surface positive regulation of T cell chemotaxis actin cytoskeleton membrane apical plasma membrane SH3 domain binding PDZ domain binding B cell differentiation positive regulation of cell growth positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of cyclin-dependent protein kinase activity during G1/S response to lipopolysaccharide ruffle membrane negative regulation of interleukin-8 production positive regulation of chemokine production regulation of mast cell apoptosis T cell differentiation in the thymus cell adhesion mediated by integrin wound healing, spreading of epidermal cells response to drug membrane raft positive regulation of epidermal growth factor receptor activity metal ion binding spleen development cell motility PMA-inducible membrane protein ectodomain proteolysis response to high density lipoprotein stimulus |
Notch signaling pathway Alzheimer's disease Epithelial cell signaling in Helicobacter pylori infection |
230486_at |
-0.310 |
5.833 |
-3.242 |
5.394e-03 |
0.352 |
-2.031 |
PCBP3 |
poly(rC) binding protein 3 |
21 |
46094302 |
BG025371 |
54039 |
21q22.3 |
Hs.474049 |
11 |
DNA binding RNA binding nucleus cytoplasm cytosol mRNA metabolic process ribonucleoprotein complex |
|
206029_at |
ANKRD1 |
ankyrin repeat domain 1 (cardiac muscle) |
10 |
-92661836 |
NM_014391 |
27063 |
10q23.31 |
Hs.448589 |
19 |
DNA binding transcription corepressor activity protein binding nucleus transcription factor complex cytoplasm regulation of transcription from RNA polymerase II promoter defense response signal transduction I band |
|
216454_at |
TRMT1 |
TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae) |
19 |
-13076713, -13076713 |
AL390133 |
55621 |
19p13.2 |
Hs.515169 |
7 |
RNA binding tRNA (guanine-N2-)-methyltransferase activity tRNA processing methyltransferase activity zinc ion binding transferase activity metal ion binding |
|
216348_at |
-0.279 |
7.452 |
-2.801 |
1.330e-02 |
0.435 |
-2.798 |
RPS17P5 |
ribosomal protein S17 pseudogene 5 |
6 |
|
AL049693 |
442216 |
6p12.3 |
|
2 |
|
|
226650_at |
0.819 |
6.071 |
4.624 |
3.196e-04 |
0.179 |
0.356 |
ZFAND2A |
zinc finger, AN1-type domain 2A |
7 |
-1159069 |
AI984061 |
90637 |
7p22.3 |
Hs.648111 |
2 |
nucleus cytoplasm zinc ion binding metal ion binding |
|
222519_s_at |
IFT57 |
intraflagellar transport 57 homolog (Chlamydomonas) |
3 |
-109362348 |
AW243004 |
55081 |
3q13.12-q13.13 |
Hs.412196 |
13 |
DNA binding protein binding Golgi apparatus cilium microtubule basal body activation of caspase activity regulation of apoptosis regulation of transcription |
Huntington's disease |
225519_at |
0.359 |
7.838 |
2.241 |
4.039e-02 |
0.569 |
-3.728 |
PPP4R2 |
protein phosphatase 4, regulatory subunit 2 |
3 |
73128808 |
AA206408 |
151987 |
3p13 |
Hs.431092 |
7 |
protein binding centrosome mRNA processing protein modification process RNA splicing |
|
33850_at |
MAP4 |
microtubule-associated protein 4 |
3 |
-47989573, -47867183, -47867183 |
W28892 |
4134 |
3p21 |
Hs.517949 |
40 |
structural molecule activity protein binding microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
211769_x_at |
0.468 |
7.546 |
2.144 |
4.859e-02 |
0.590 |
-3.880 |
SERINC3 |
serine incorporator 3 |
20 |
-42561314, -42558277 |
BC006088 |
10955 |
20q13.1-q13.3 |
Hs.272168 Hs.696043 |
10 |
protein binding Golgi apparatus plasma membrane induction of apoptosis integral to membrane |
|
211120_x_at |
ESR2 |
estrogen receptor 2 (ER beta) |
14 |
-63769499, -63763503, -63763503 |
AB006590 |
2100 |
14q23.2 |
Hs.525392 Hs.660607 |
488 |
transcription factor activity transcription coactivator activity steroid binding protein binding nucleus mitochondrion regulation of transcription, DNA-dependent signal transduction cell-cell signaling zinc ion binding estrogen receptor activity negative regulation of cell growth estrogen receptor signaling pathway sequence-specific DNA binding metal ion binding receptor antagonist activity |
|
235590_at |
FAM178A |
family with sequence similarity 178, member A |
10 |
102662315, 102662315, 102662315 |
BF112155 |
55719 |
10q24.31 |
Hs.447458 |
5 |
|
|
206791_s_at |
PDE4C |
phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) |
19 |
-18179770, -18179770, -18179770 |
BF511742 |
5143 |
19p13.11 |
Hs.132584 |
13 |
3',5'-cyclic-AMP phosphodiesterase activity signal transduction hydrolase activity |
Purine metabolism |
216347_s_at |
0.272 |
6.265 |
2.567 |
2.131e-02 |
0.497 |
-3.195 |
PPP1R13B |
protein phosphatase 1, regulatory (inhibitor) subunit 13B |
14 |
-103269840 |
AK023188 |
23368 |
14q32.33 |
Hs.709297 |
13 |
protein binding nucleus cytoplasm apoptosis induction of apoptosis negative regulation of cell cycle |
|
220239_at |
0.468 |
4.141 |
2.343 |
3.312e-02 |
0.551 |
-3.564 |
KLHL7 |
kelch-like 7 (Drosophila) |
7 |
23111877 |
NM_018846 |
55975 |
7p15.3 |
Hs.654817 |
9 |
protein binding nucleus nucleolus |
|
204958_at |
PLK3 |
polo-like kinase 3 (Drosophila) |
1 |
45038622 |
NM_004073 |
1263 |
1p34.1 |
Hs.632415 |
33 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation cell cycle membrane transferase activity dendrite polo kinase kinase activity |
|
208751_at |
NAPA |
N-ethylmaleimide-sensitive factor attachment protein, alpha |
19 |
-52682702 |
BC001165 |
8775 |
19q13.32-q13.33 |
Hs.126938 Hs.719083 |
27 |
protein binding endoplasmic reticulum Golgi apparatus intracellular protein transport intra-Golgi vesicle-mediated transport membrane fusion brain development membrane vesicle-mediated transport syntaxin binding neuron differentiation apical protein localization |
|
217943_s_at |
MAP7D1 |
MAP7 domain containing 1 |
1 |
36394389 |
NM_018067 |
55700 |
1p34.3 |
Hs.700595 |
7 |
spindle |
|
204001_at |
SNAPC3 |
small nuclear RNA activating complex, polypeptide 3, 50kDa |
9 |
15412781 |
NM_003084 |
6619 |
9p22.3 |
Hs.546299 |
12 |
DNA binding protein binding nucleus transcription from RNA polymerase II promoter transcription from RNA polymerase III promoter snRNA transcription regulation of transcription |
|
222617_s_at |
0.431 |
7.394 |
2.336 |
3.359e-02 |
0.552 |
-3.576 |
C10orf84 |
chromosome 10 open reading frame 84 |
10 |
-120058561 |
AI147026 |
63877 |
10q26.11 |
Hs.372309 |
5 |
|
|
1552848_a_at |
-0.444 |
4.164 |
-3.403 |
3.869e-03 |
0.319 |
-1.748 |
PTCHD1 |
patched domain containing 1 |
X |
23262905 |
NM_173495 |
139411 |
Xp22.11 |
Hs.319503 |
2 |
hedgehog receptor activity membrane integral to membrane |
|
206146_s_at |
RHAG |
Rh-associated glycoprotein |
6 |
-49680848 |
AF178841 |
6005 |
6p21.1-p11 |
Hs.120950 |
35 |
plasma membrane plasma membrane integral to plasma membrane transport cellular ion homeostasis ammonium transmembrane transporter activity ammonium transmembrane transporter activity carbon dioxide transport ammonium transport ammonium transport ankyrin binding ammonia transporter activity |
|
221325_at |
-0.250 |
4.524 |
-3.467 |
3.386e-03 |
0.308 |
-1.635 |
KCNK13 |
potassium channel, subfamily K, member 13 |
14 |
89597860 |
NM_022054 |
56659 |
14q31-q32 |
Hs.510191 |
8 |
voltage-gated ion channel activity potassium channel activity ion transport potassium ion transport membrane integral to membrane potassium ion binding |
|
1555083_at |
-0.204 |
6.198 |
-2.280 |
3.744e-02 |
0.563 |
-3.666 |
RPL13AP17 |
ribosomal protein L13a pseudogene 17 |
7 |
77814494 |
BC027852 |
399670 |
7q21.11 |
Hs.568045 |
3 |
|
|
1562495_at |
ANKFY1 |
ankyrin repeat and FYVE domain containing 1 |
17 |
-4044521, -4013413 |
BM970179 |
51479 |
17p13.3 |
Hs.696087 |
11 |
protein binding cytoplasm endosome zinc ion binding endosome membrane membrane metal ion binding |
|
220166_at |
CNNM1 |
cyclin M1 |
10 |
101078845 |
NM_020348 |
26507 |
10q24.2 |
Hs.274579 |
5 |
plasma membrane ion transport integral to membrane |
|
217011_at |
-0.314 |
5.787 |
-2.662 |
1.760e-02 |
0.473 |
-3.034 |
GBX1 |
gastrulation brain homeobox 1 |
7 |
-150476608 |
L11239 |
2636 |
7q36 |
Hs.647114 |
4 |
nuclear chromosome transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
235918_x_at |
CEP97 |
centrosomal protein 97kDa |
3 |
102926183 |
AL559474 |
79598 |
3q12.3 |
Hs.444135 |
9 |
protein binding cytoplasm centrosome |
|
201212_at |
LGMN |
legumain |
14 |
-92239907 |
D55696 |
5641 |
14q32.1 |
Hs.719135 |
17 |
cysteine-type endopeptidase activity protein serine/threonine kinase activity cytoplasm lysosome late endosome proteolysis peptidase activity negative regulation of multicellular organism growth intracellular membrane-bounded organelle apical part of cell |
Lysosome Antigen processing and presentation |
219281_at |
0.461 |
7.662 |
2.725 |
1.550e-02 |
0.458 |
-2.927 |
MSRA |
methionine sulfoxide reductase A |
8 |
9949239, 9990475 |
NM_012331 |
4482 |
8p23.1 |
Hs.490981 |
22 |
protein modification process methionine metabolic process response to oxidative stress peptide-methionine-(S)-S-oxide reductase activity oxidoreductase activity protein metabolic process oxidation reduction |
|
214553_s_at |
ARPP19 |
cAMP-regulated phosphoprotein, 19kDa |
15 |
-50626723 |
NM_006628 |
10776 |
15q21.2 |
Hs.512908 |
10 |
receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import |
|
201986_at |
MED13 |
mediator complex subunit 13 |
17 |
-57374747 |
AB011165 |
9969 |
17q22-q23 |
Hs.282678 |
26 |
receptor activity nucleus transcription initiation from RNA polymerase II promoter RNA polymerase II transcription mediator activity ligand-dependent nuclear receptor transcription coactivator activity androgen receptor signaling pathway vitamin D receptor binding regulation of transcription positive regulation of transcription from RNA polymerase II promoter thyroid hormone receptor binding |
|
202582_s_at |
RANBP9 |
RAN binding protein 9 |
6 |
-13729708 |
AF306510 |
10048 |
6p23 |
Hs.708182 |
37 |
nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding |
|
235684_s_at |
SESN3 |
sestrin 3 |
11 |
-94545780 |
BF685808 |
143686 |
11q21 |
Hs.659934 |
4 |
nucleus cell cycle arrest |
p53 signaling pathway |
232977_x_at |
MYH14 |
myosin, heavy chain 14 |
19 |
55398696 |
BC004396 |
79784 |
19q13.33 |
Hs.467142 |
19 |
nucleotide binding motor activity actin binding calmodulin binding ATP binding regulation of cell shape myosin complex |
Tight junction Regulation of actin cytoskeleton |
207093_s_at |
-0.244 |
5.278 |
-2.180 |
4.541e-02 |
0.581 |
-3.825 |
OMG |
oligodendrocyte myelin glycoprotein |
17 |
-26645794 |
NM_002544 |
4974 |
17q11.2 |
Hs.113874 |
16 |
protein binding plasma membrane cell adhesion anchored to membrane |
|
60815_at |
POLR2J4 |
polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
7 |
-43947018 |
AA601208 |
84820 |
7p13 |
Hs.657028 |
5 |
|
|
238528_at |
UBR1 |
ubiquitin protein ligase E3 component n-recognin 1 |
15 |
-41022389 |
AI361043 |
197131 |
15q13 |
Hs.591121 |
21 |
ubiquitin ligase complex proteasome complex ubiquitin-protein ligase activity protein binding cytoplasm cytosol ubiquitin-dependent protein catabolic process zinc ion binding ligase activity protein catabolic process metal ion binding |
|
214369_s_at |
RASGRP2 |
RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
11 |
-64250958, -64250958, -64250958 |
AI688812 |
10235 |
11q13 |
Hs.99491 |
11 |
regulation of cell growth guanyl-nucleotide exchange factor activity calcium ion binding calcium ion binding intracellular cytoplasm cytosol plasma membrane Ras protein signal transduction zinc ion binding synaptosome diacylglycerol binding cell junction cell projection synapse regulation of small GTPase mediated signal transduction |
MAPK signaling pathway Chemokine signaling pathway |
209682_at |
0.576 |
6.375 |
3.812 |
1.663e-03 |
0.263 |
-1.031 |
CBLB |
Cas-Br-M (murine) ecotropic retroviral transforming sequence b |
3 |
-106859798 |
U26710 |
868 |
3q13.11 |
Hs.430589 |
44 |
signal transducer activity calcium ion binding protein binding nucleus cytoplasm NLS-bearing substrate import into nucleus immune response cell surface receptor linked signal transduction zinc ion binding ligase activity modification-dependent protein catabolic process |
ErbB signaling pathway Ubiquitin mediated proteolysis Endocytosis Jak-STAT signaling pathway T cell receptor signaling pathway Insulin signaling pathway Pathways in cancer Chronic myeloid leukemia |
204209_at |
PCYT1A |
phosphate cytidylyltransferase 1, choline, alpha |
3 |
-197449649 |
AI638771 |
5130 |
3q29 |
Hs.435767 |
15 |
choline-phosphate cytidylyltransferase activity soluble fraction cytoplasm endoplasmic reticulum membrane cytosol phosphatidylcholine biosynthetic process phospholipid biosynthetic process biosynthetic process response to abiotic stimulus membrane transferase activity nucleotidyltransferase activity glycogen granule |
Aminophosphonate metabolism Glycerophospholipid metabolism Metabolic pathways |
1555971_s_at |
FBXO28 |
F-box protein 28 |
1 |
222368413 |
AU154086 |
23219 |
1q42.11 |
Hs.64691 Hs.713992 |
10 |
modification-dependent protein catabolic process |
|
240409_at |
SUGT1L1 |
SGT1, suppressor of G2 allele of SKP1 like 1 (S. cerevisiae) |
13 |
-40269126 |
AI203405 |
283507 |
13q14.11 |
Hs.442781 Hs.709973 |
2 |
|
|
1561892_at |
ZMYM6 |
zinc finger, MYM-type 6 |
1 |
-35224353 |
BC043174 |
9204 |
1p34.2 |
Hs.533986 Hs.623978 Hs.675613 |
8 |
DNA binding nucleus nucleolus multicellular organismal development zinc ion binding metal ion binding |
|
217730_at |
TMBIM1 |
transmembrane BAX inhibitor motif containing 1 |
2 |
-218847160 |
NM_022152 |
64114 |
2p24.3-p24.1 |
Hs.591605 |
9 |
membrane integral to membrane |
|
224574_at |
C17orf49 |
chromosome 17 open reading frame 49 |
17 |
6858796 |
AV759602 |
124944 |
17p13.1 |
Hs.511801 |
7 |
DNA binding nucleus |
|
91684_g_at |
0.347 |
6.190 |
2.487 |
2.494e-02 |
0.513 |
-3.327 |
EXOSC4 |
exosome component 4 |
8 |
145205509 |
AI571298 |
54512 |
8q24.3 |
Hs.632041 |
16 |
3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity |
RNA degradation |
203004_s_at |
MEF2D |
myocyte enhancer factor 2D |
1 |
-154700142 |
NM_005920 |
4209 |
1q12-q23 |
Hs.314327 |
35 |
transcription factor activity nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding |
|
201841_s_at |
HSPB1 |
heat shock 27kDa protein 1 |
7 |
75769810 |
NM_001540 |
3315 |
7q11.23 |
Hs.520973 |
153 |
nucleus cytoplasm spindle cytoskeleton regulation of translational initiation anti-apoptosis cell motion response to unfolded protein cell death response to heat cell surface identical protein binding |
MAPK signaling pathway VEGF signaling pathway |
225843_at |
ZFYVE19 |
zinc finger, FYVE domain containing 19 |
15 |
38886565 |
AW015263 |
84936 |
15q15.1 |
Hs.121676 |
8 |
protein binding zinc ion binding metal ion binding |
|
208652_at |
0.362 |
9.460 |
2.529 |
2.297e-02 |
0.503 |
-3.258 |
PPP2CA |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform |
5 |
-133560046 |
BC000400 |
5515 |
5q31.1 |
Hs.105818 |
105 |
protein phosphatase type 2A complex inactivation of MAPK activity chromosome, centromeric region phosphoprotein phosphatase activity iron ion binding protein binding soluble fraction nucleus cytoplasm mitochondrion spindle cytosol plasma membrane regulation of DNA replication protein amino acid dephosphorylation ceramide metabolic process induction of apoptosis mesoderm development RNA splicing response to organic substance hydrolase activity second-messenger-mediated signaling regulation of Wnt receptor signaling pathway manganese ion binding regulation of cell adhesion negative regulation of cell growth regulation of growth negative regulation of tyrosine phosphorylation of Stat3 protein regulation of transcription regulation of cell differentiation metal ion binding protein heterodimerization activity |
Wnt signaling pathway TGF-beta signaling pathway Tight junction Long-term depression |
211684_s_at |
0.341 |
8.353 |
2.836 |
1.239e-02 |
0.427 |
-2.738 |
DYNC1I2 |
dynein, cytoplasmic 1, intermediate chain 2 |
2 |
172252227 |
AF250307 |
1781 |
2q31.1 |
Hs.546250 |
17 |
microtubule motor activity protein binding cytoplasm microtubule microtubule-based movement dynein complex |
|
213092_x_at |
DNAJC9 |
DnaJ (Hsp40) homolog, subfamily C, member 9 |
10 |
-74672587 |
AW241779 |
23234 |
10q22.2 |
Hs.654694 |
4 |
heat shock protein binding |
|
201156_s_at |
RAB5C |
RAB5C, member RAS oncogene family |
17 |
-37530522 |
AF141304 |
5878 |
17q21.2 |
Hs.650382 |
11 |
nucleotide binding GTPase activity protein binding GTP binding endosome plasma membrane endosome organization small GTPase mediated signal transduction protein transport regulation of endocytosis endocytic vesicle melanosome |
Endocytosis |
205219_s_at |
GALK2 |
galactokinase 2 |
15 |
47235267, 47249713 |
NM_002044 |
2585 |
15q21.1-q21.2 |
Hs.122006 Hs.712959 |
8 |
nucleotide binding galactokinase activity ATP binding cytoplasm carbohydrate metabolic process galactose metabolic process metabolic process kinase activity transferase activity N-acetylgalactosamine kinase activity carbohydrate phosphorylation |
Galactose metabolism Amino sugar and nucleotide sugar metabolism Metabolic pathways |
204009_s_at |
0.387 |
7.833 |
2.238 |
4.062e-02 |
0.570 |
-3.733 |
KRAS |
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
12 |
-25249446 |
W80678 |
3845 |
12p12.1 |
Hs.505033 |
430 |
nucleotide binding protein binding GTP binding intracellular membrane fraction plasma membrane plasma membrane endocytosis Ras protein signal transduction cell aging positive regulation of cell proliferation visual learning actin cytoskeleton organization regulation of synaptic transmission, GABAergic positive regulation of Rac protein signal transduction negative regulation of neuron apoptosis regulation of long-term neuronal synaptic plasticity striated muscle cell differentiation |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Axon guidance VEGF signaling pathway Tight junction Gap junction Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
209384_at |
PROSC |
proline synthetase co-transcribed homolog (bacterial) |
8 |
37739258 |
AA176833 |
11212 |
8p11.2 |
Hs.304792 Hs.608177 |
8 |
intracellular cytoplasm |
|
230280_at |
0.392 |
2.830 |
2.318 |
3.475e-02 |
0.555 |
-3.604 |
TRIM9 |
tripartite motif-containing 9 |
14 |
-50532534, -50511730 |
BF057241 |
114088 |
14q22.1 |
Hs.654750 |
11 |
protein binding intracellular cytoplasm zinc ion binding protein homodimerization activity metal ion binding |
|
217885_at |
0.249 |
7.351 |
2.334 |
3.373e-02 |
0.552 |
-3.579 |
IPO9 |
importin 9 |
1 |
200064910 |
NM_018085 |
55705 |
1q32.1 |
Hs.596014 |
12 |
protein import into nucleus, docking nucleus nuclear pore cytoplasm intracellular protein transport Ran GTPase binding protein transporter activity histone binding |
|
244789_at |
C10orf122 |
chromosome 10 open reading frame 122 |
10 |
-127334252 |
AW082215 |
387718 |
10q26.13 |
Hs.148259 |
3 |
|
|
1554351_a_at |
0.552 |
6.182 |
2.222 |
4.184e-02 |
0.574 |
-3.757 |
TIPRL |
TIP41, TOR signaling pathway regulator-like (S. cerevisiae) |
1 |
166414794, 166414794 |
BC009506 |
261726 |
1q23.2 |
Hs.209431 |
7 |
protein binding |
|
223138_s_at |
DHX36 |
DEAH (Asp-Glu-Ala-His) box polypeptide 36 |
3 |
-155476150 |
AI937206 |
170506 |
3p13-q23 |
Hs.446270 |
13 |
nucleotide binding nucleic acid binding helicase activity protein binding ATP binding nucleus cytoplasm ATP-dependent helicase activity hydrolase activity |
|
212426_s_at |
YWHAQ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide |
2 |
-9641556 |
BF033313 |
10971 |
2p25.1 |
Hs.74405 |
93 |
cytoplasm protein targeting small GTPase mediated signal transduction protein domain specific binding negative regulation of transcription, DNA-dependent protein N-terminus binding |
Cell cycle Neurotrophin signaling pathway Pathogenic Escherichia coli infection - EHEC |
222671_s_at |
0.267 |
5.483 |
2.154 |
4.768e-02 |
0.586 |
-3.865 |
JMJD4 |
jumonji domain containing 4 |
1 |
-225985513 |
AA582199 |
65094 |
1q42.13 |
Hs.325081 Hs.555974 |
2 |
|
|
231158_x_at |
PTBP1 |
polypyrimidine tract binding protein 1 |
19 |
748391 |
AI380289 |
5725 |
19p13.3 |
Hs.172550 |
65 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus poly-pyrimidine tract binding RNA splicing heterogeneous nuclear ribonucleoprotein complex |
|
202947_s_at |
GYPC |
glycophorin C (Gerbich blood group) |
2 |
127130153 |
NM_002101 |
2995 |
2q14-q21 |
Hs.59138 |
31 |
protein binding plasma membrane integral to plasma membrane protein amino acid N-linked glycosylation protein amino acid O-linked glycosylation organ morphogenesis cortical cytoskeleton |
|
1558217_at |
SLFN13 |
schlafen family member 13 |
17 |
-30786227 |
AK074465 |
146857 |
17q12 |
Hs.462833 |
8 |
nucleotide binding ATP binding intracellular |
|
212972_x_at |
APBB2 |
amyloid beta (A4) precursor protein-binding, family B, member 2 |
4 |
-40506801 |
AL080130 |
323 |
4p14-p13 |
Hs.479602 |
12 |
beta-amyloid binding nucleus cell cycle arrest intracellular signaling cascade transcription factor binding membrane lamellipodium negative regulation of cell growth growth cone synapse regulation of transcription negative regulation of S phase of mitotic cell cycle |
|
212355_at |
KIAA0323 |
KIAA0323 |
14 |
23968980 |
AI075450 |
23351 |
14q12 |
Hs.713590 |
5 |
|
|
203743_s_at |
TDG |
thymine-DNA glycosylase |
12 |
102883722 |
NM_003211 |
6996 |
12q24.1 |
Hs.584809 |
47 |
damaged DNA binding protein binding nucleus nucleoplasm nucleoplasm base-excision repair mismatch repair response to DNA damage stimulus metabolic process pyrimidine-specific mismatch base pair DNA N-glycosylase activity DNA N-glycosylase activity mismatched DNA binding depyrimidination |
Base excision repair |
220955_x_at |
RAB23 |
RAB23, member RAS oncogene family |
6 |
-57161540, -57161540 |
NM_016277 |
51715 |
6p11 |
Hs.555016 |
11 |
nucleotide binding GTP binding plasma membrane signal transduction small GTPase mediated signal transduction nervous system development regulation of smoothened signaling pathway protein transport spinal cord dorsal/ventral patterning embryonic digit morphogenesis negative regulation of proteolysis |
Hedgehog signaling pathway |
220077_at |
CCDC134 |
coiled-coil domain containing 134 |
22 |
40526623 |
NM_024821 |
79879 |
22q13.2 |
Hs.474991 |
7 |
extracellular region |
|
220805_at |
HRH2 |
histamine receptor H2 |
5 |
175017645, 175041069 |
NM_022304 |
3274 |
5q35.2 |
Hs.247885 Hs.716212 |
41 |
receptor activity G-protein coupled receptor activity histamine receptor activity plasma membrane integral to plasma membrane immune response signal transduction G-protein signaling, coupled to cyclic nucleotide second messenger |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
204686_at |
-0.957 |
8.297 |
-3.063 |
7.791e-03 |
0.381 |
-2.344 |
IRS1 |
insulin receptor substrate 1 |
2 |
-227304276 |
NM_005544 |
3667 |
2q36 |
Hs.471508 |
290 |
positive regulation of mesenchymal cell proliferation signal transducer activity transmembrane receptor protein tyrosine kinase docking protein activity protein kinase C binding insulin receptor binding insulin-like growth factor receptor binding protein binding nucleus cytoplasm microsome plasma membrane insulin receptor complex caveola signal transduction positive regulation of glucose metabolic process phosphoinositide 3-kinase cascade positive regulation of cell migration mammary gland development positive regulation of fatty acid beta-oxidation SH2 domain binding glucose homeostasis response to peptide hormone stimulus protein kinase B signaling cascade phosphoinositide 3-kinase binding phosphoinositide 3-kinase binding positive regulation of phosphoinositide 3-kinase activity positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process positive regulation of glucose import negative regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway |
Neurotrophin signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus |
202125_s_at |
0.422 |
7.220 |
2.446 |
2.707e-02 |
0.525 |
-3.396 |
TRAK2 |
trafficking protein, kinesin binding 2 |
2 |
-201950174 |
NM_015049 |
66008 |
2q33 |
Hs.152774 |
16 |
cytoplasm plasma membrane GABA receptor binding |
|
216051_x_at |
PRINS |
psoriasis associated RNA induced by stress (non-protein coding) |
10 |
24576059 |
AK022045 |
100169750 |
10p12.1 |
Hs.655386 |
2 |
|
|
225844_at |
POLE4 |
polymerase (DNA-directed), epsilon 4 (p12 subunit) |
2 |
75039282 |
NM_019896 |
56655 |
2p12 |
Hs.469060 |
5 |
DNA-directed DNA polymerase activity protein binding intracellular nucleus transferase activity nucleotidyltransferase activity sequence-specific DNA binding |
Purine metabolism Pyrimidine metabolism Metabolic pathways DNA replication Base excision repair Nucleotide excision repair |
1562617_at |
-0.238 |
4.110 |
-2.324 |
3.437e-02 |
0.553 |
-3.595 |
LOC340074 |
hypothetical LOC340074 |
5 |
-135012272 |
BC040891 |
340074 |
5q31.1 |
Hs.434633 |
1 |
|
|
1557719_at |
0.228 |
5.131 |
2.365 |
3.175e-02 |
0.544 |
-3.529 |
PIKFYVE |
phosphoinositide kinase, FYVE finger containing |
2 |
208839235, 208839235 |
BC017736 |
200576 |
2q34 |
Hs.173939 |
25 |
nucleotide binding protein binding ATP binding endosome receptor-mediated endocytosis intracellular signaling cascade zinc ion binding membrane kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity transferase activity early endosome membrane protein localization in nucleus retrograde transport, endosome to Golgi cellular protein metabolic process membrane raft phosphatidylinositol metabolic process metal ion binding |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system Endocytosis Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
209158_s_at |
0.307 |
7.138 |
2.612 |
1.945e-02 |
0.489 |
-3.119 |
CYTH2 |
cytohesin 2 |
19 |
53664276 |
BC004361 |
9266 |
19q13.33 |
Hs.144011 |
34 |
ARF guanyl-nucleotide exchange factor activity protein binding intracellular membrane fraction plasma membrane endocytosis actin cytoskeleton organization regulation of ARF protein signal transduction |
|
212815_at |
ASCC3 |
activating signal cointegrator 1 complex subunit 3 |
6 |
-101410899, -101063328 |
AA156961 |
10973 |
6q16.1-q16.3 |
Hs.486031 |
10 |
nucleotide binding nucleic acid binding helicase activity ATP binding intracellular cytoplasm ATP-dependent helicase activity hydrolase activity regulation of transcription |
|
229433_at |
RBM26 |
RNA binding motif protein 26 |
13 |
-78792099 |
AU144571 |
64062 |
13q31.1 |
Hs.558528 |
8 |
nucleotide binding RNA binding zinc ion binding metal ion binding |
|
221667_s_at |
0.438 |
11.262 |
2.195 |
4.409e-02 |
0.579 |
-3.800 |
HSPB8 |
heat shock 22kDa protein 8 |
12 |
118100977 |
AF133207 |
26353 |
12q24.23 |
Hs.400095 |
48 |
protein serine/threonine kinase activity cellular_component intracellular biological_process cell death response to heat identical protein binding |
|
229287_at |
PCNX |
pecanex homolog (Drosophila) |
14 |
70443874 |
BE326214 |
22990 |
14q24.2 |
Hs.446559 |
10 |
membrane integral to membrane |
|
202879_s_at |
CYTH1 |
cytohesin 1 |
17 |
-74181724 |
AI798823 |
9267 |
17q25 |
Hs.191215 |
28 |
ARF guanyl-nucleotide exchange factor activity protein binding intracellular cytoplasm plasma membrane vesicle-mediated transport regulation of cell adhesion regulation of ARF protein signal transduction |
|
221979_at |
0.405 |
7.309 |
3.222 |
5.617e-03 |
0.354 |
-2.066 |
LOC100129250 |
similar to hCG1811779 |
9 |
|
AI150117 |
100129250 |
9p21.1 |
Hs.664395 |
|
|
|
200765_x_at |
CTNNA1 |
catenin (cadherin-associated protein), alpha 1, 102kDa |
5 |
138117005 |
NM_001903 |
1495 |
5q31 |
Hs.534797 Hs.656653 |
70 |
structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding |
Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
234290_x_at |
MYH14 |
myosin, heavy chain 14 |
19 |
55398696 |
BC000676 |
79784 |
19q13.33 |
Hs.467142 |
19 |
nucleotide binding motor activity actin binding calmodulin binding ATP binding regulation of cell shape myosin complex |
Tight junction Regulation of actin cytoskeleton |
229105_at |
GPR39 |
G protein-coupled receptor 39 |
2 |
132890616 |
AV717094 |
2863 |
2q21-q22 |
Hs.432395 Hs.719231 |
14 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway zinc ion binding metal ion binding |
|
218187_s_at |
0.258 |
6.176 |
2.813 |
1.296e-02 |
0.432 |
-2.776 |
C8orf33 |
chromosome 8 open reading frame 33 |
8 |
146248627 |
NM_023080 |
65265 |
8q24.3 |
Hs.169615 |
3 |
|
|
233954_at |
-0.425 |
3.409 |
-3.878 |
1.452e-03 |
0.250 |
-0.916 |
HIATL1 |
hippocampus abundant transcript-like 1 |
9 |
96176653 |
AL110135 |
84641 |
9q22.32 |
Hs.555996 Hs.715500 |
7 |
transporter activity protein binding transport tetracycline:hydrogen antiporter activity tetracycline transport membrane integral to membrane response to antibiotic |
|
205736_at |
-0.956 |
11.227 |
-3.283 |
4.949e-03 |
0.343 |
-1.958 |
PGAM2 |
phosphoglycerate mutase 2 (muscle) |
7 |
-44068850 |
NM_000290 |
5224 |
7p13-p12 |
Hs.632642 |
9 |
bisphosphoglycerate mutase activity 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity phosphoglycerate mutase activity cellular_component glycolysis striated muscle contraction metabolic process hydrolase activity isomerase activity |
Glycolysis / Gluconeogenesis Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
211306_s_at |
FCAR |
Fc fragment of IgA, receptor for |
19 |
60077360, 60077360 |
U56237 |
2204 |
19q13.2-q13.4 |
Hs.659872 |
52 |
receptor activity extracellular region plasma membrane integral to plasma membrane immune response IgA binding |
|
222875_at |
0.462 |
6.775 |
3.572 |
2.729e-03 |
0.290 |
-1.451 |
DHX33 |
DEAH (Asp-Glu-Ala-His) box polypeptide 33 |
17 |
-5286314 |
AI720923 |
56919 |
17p13.2 |
Hs.250456 |
4 |
nucleotide binding nucleic acid binding helicase activity ATP binding nucleus nucleolus ATP-dependent helicase activity hydrolase activity |
|
200685_at |
SFRS11 |
splicing factor, arginine/serine-rich 11 |
1 |
70443952 |
AU146237 |
9295 |
1p31 |
Hs.479693 |
13 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleolus RNA splicing |
|
229927_at |
LEMD1 |
LEM domain containing 1 |
1 |
-203617135 |
BE222220 |
93273 |
1q32.1 |
Hs.655520 |
2 |
nuclear envelope membrane integral to membrane |
|
208135_at |
HNF1B |
HNF1 homeobox B |
17 |
-33120546 |
NM_006481 |
6928 |
17cen-q21.3 |
Hs.191144 |
87 |
kidney development transcription factor activity nucleus nucleolus transcription activator activity sequence-specific DNA binding positive regulation of transcription, DNA-dependent |
Maturity onset diabetes of the young |
207498_s_at |
CYP2D6 |
cytochrome P450, family 2, subfamily D, polypeptide 6 |
22 |
-40852444 |
NM_000106 |
1565 |
22q13.1 |
Hs.648256 |
524 |
endoplasmic reticulum microsome electron carrier activity membrane drug metabolic process heme binding metal ion binding oxidation reduction aromatase activity |
Drug metabolism - cytochrome P450 Biosynthesis of alkaloids derived from shikimate pathway |
211820_x_at |
-0.265 |
3.783 |
-2.987 |
9.092e-03 |
0.398 |
-2.475 |
GYPA |
glycophorin A (MNS blood group) |
4 |
-145249905 |
U00179 |
2993 |
4q28.2-q31.1 |
Hs.434973 |
60 |
membrane fraction plasma membrane integral to membrane identical protein binding |
Hematopoietic cell lineage |
227028_s_at |
DGCR2 |
DiGeorge syndrome critical region gene 2 |
22 |
-17403794 |
AA534295 |
9993 |
22q11.21 |
Hs.517357 |
14 |
receptor activity protein binding sugar binding microsome cell adhesion organ morphogenesis membrane integral to membrane response to drug |
|
222418_s_at |
1.023 |
7.610 |
3.207 |
5.797e-03 |
0.357 |
-2.093 |
TMEM43 |
transmembrane protein 43 |
3 |
14141440 |
AA115485 |
79188 |
3p25.1 |
Hs.517817 |
18 |
nucleus endoplasmic reticulum Golgi apparatus membrane integral to membrane |
|
224801_at |
NDFIP2 |
Nedd4 family interacting protein 2 |
13 |
78953259 |
AI655642 |
54602 |
13q31.1 |
Hs.525093 |
12 |
signal transducer activity protein binding cytoplasm mitochondrion endosome endoplasmic reticulum Golgi apparatus negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm WW domain binding negative regulation of protein transport |
|
1559571_a_at |
ATP13A4 |
ATPase type 13A4 |
3 |
-194602559 |
AK095277 |
84239 |
3q29 |
Hs.674423 |
4 |
nucleotide binding magnesium ion binding ATP binding ATP biosynthetic process cation transport ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity |
|
1559942_at |
0.398 |
4.414 |
2.287 |
3.693e-02 |
0.562 |
-3.654 |
MDFIC |
MyoD family inhibitor domain containing |
7 |
114349444 |
BC040713 |
29969 |
7q31.1-q31.2 |
Hs.427236 |
7 |
nucleus nucleolus cytoplasm activation of JUN kinase activity regulation of Wnt receptor signaling pathway cyclin binding Tat protein binding interspecies interaction between organisms regulation of transcription positive regulation of viral transcription |
|
228079_at |
C3orf58 |
chromosome 3 open reading frame 58 |
3 |
145173329, 145174856 |
AI343351 |
205428 |
3q24 |
Hs.288954 |
5 |
extracellular region |
|
225026_at |
CHD6 |
chromodomain helicase DNA binding protein 6 |
20 |
-39464583 |
BF572029 |
84181 |
20q12 |
Hs.371979 |
12 |
nucleotide binding chromatin DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly chromatin remodeling regulation of transcription, DNA-dependent nervous system development ATP-dependent helicase activity hydrolase activity |
|
225700_at |
-0.294 |
3.837 |
-2.442 |
2.725e-02 |
0.526 |
-3.401 |
GLCCI1 |
glucocorticoid induced transcript 1 |
7 |
7974947 |
AC006042 |
113263 |
7p21.3 |
Hs.131673 |
9 |
|
|
201944_at |
0.474 |
7.742 |
3.280 |
4.987e-03 |
0.343 |
-1.964 |
HEXB |
hexosaminidase B (beta polypeptide) |
5 |
74016724 |
NM_000521 |
3074 |
5q13 |
Hs.69293 |
66 |
skeletal system development acrosomal vesicle hydrolase activity, hydrolyzing O-glycosyl compounds beta-N-acetylhexosaminidase activity lysosome carbohydrate metabolic process glycosphingolipid metabolic process ganglioside catabolic process cellular calcium ion homeostasis lysosome organization penetration of zona pellucida sensory perception of sound locomotory behavior male courtship behavior metabolic process phospholipid biosynthetic process oligosaccharide catabolic process membrane lipid storage sexual reproduction glycosaminoglycan metabolic process regulation of cellular metabolic process myelination protein homodimerization activity cation binding cellular protein metabolic process protein heterodimerization activity oogenesis neuromuscular process controlling balance |
Other glycan degradation Amino sugar and nucleotide sugar metabolism Glycosaminoglycan degradation Glycosphingolipid biosynthesis - globo series Glycosphingolipid biosynthesis - ganglio series Metabolic pathways Lysosome |
1563728_at |
NCRNA00032 |
non-protein coding RNA 32 |
9 |
-27235683 |
AF418573 |
158035 |
9p21 |
Hs.201554 |
1 |
|
|
208029_s_at |
LAPTM4B |
lysosomal protein transmembrane 4 beta |
8 |
98856984 |
NM_018407 |
55353 |
8q22.1 |
Hs.492314 |
17 |
transport endomembrane system membrane integral to membrane |
Lysosome |
1557981_at |
-0.272 |
4.118 |
-2.938 |
1.006e-02 |
0.415 |
-2.561 |
RPS9 |
ribosomal protein S9 |
19 |
59396537 |
AK095055 |
6203 |
19q13.4 |
Hs.467284 Hs.546288 |
20 |
structural constituent of ribosome protein binding intracellular nucleolus cytoplasm cytosol ribosome translational elongation positive regulation of cell proliferation rRNA binding cytosolic small ribosomal subunit translation regulator activity |
Ribosome |
203535_at |
0.479 |
4.123 |
2.663 |
1.758e-02 |
0.473 |
-3.033 |
S100A9 |
S100 calcium binding protein A9 |
1 |
151596953 |
NM_002965 |
6280 |
1q21 |
Hs.112405 |
102 |
signal transducer activity calcium ion binding protein binding nucleus nucleolus cytoplasm inflammatory response cell-cell signaling leukocyte chemotaxis actin cytoskeleton reorganization regulation of integrin biosynthetic process |
|
1563228_x_at |
SLC38A10 |
solute carrier family 38, member 10 |
17 |
-76839265, -76833393 |
BC020925 |
124565 |
17q25.3 |
Hs.352240 |
2 |
ion transport sodium ion transport amino acid transport membrane integral to membrane sodium ion binding |
|
201574_at |
0.375 |
8.905 |
2.683 |
1.689e-02 |
0.467 |
-3.000 |
ETF1 |
eukaryotic translation termination factor 1 |
5 |
-137869682 |
NM_004730 |
2107 |
5q31.1 |
Hs.483494 |
32 |
RNA binding protein binding cytoplasm regulation of translational termination protein amino acid methylation translation release factor activity, codon specific ribosome binding |
|
204605_at |
CGRRF1 |
cell growth regulator with ring finger domain 1 |
14 |
54046336 |
NM_006568 |
10668 |
14q22.2 |
Hs.59106 |
5 |
protein binding response to stress cell cycle cell cycle arrest zinc ion binding negative regulation of cell proliferation negative regulation of cell growth metal ion binding |
|
201274_at |
0.242 |
8.803 |
2.553 |
2.190e-02 |
0.499 |
-3.218 |
PSMA5 |
proteasome (prosome, macropain) subunit, alpha type, 5 |
1 |
-109745994 |
NM_002790 |
5686 |
1p13 |
Hs.712557 |
45 |
threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
228459_at |
FAM84A |
family with sequence similarity 84, member A |
2 |
14690306 |
BF063776 |
151354 |
2p24.3 |
Hs.260855 |
6 |
|
|
212017_at |
0.226 |
8.302 |
2.251 |
3.955e-02 |
0.568 |
-3.711 |
FAM168B |
family with sequence similarity 168, member B |
2 |
-131521918 |
BF677404 |
130074 |
2q21.1 |
Hs.534679 |
2 |
|
|
1558119_at |
-0.222 |
4.851 |
-2.182 |
4.520e-02 |
0.581 |
-3.821 |
TSPAN17 |
tetraspanin 17 |
5 |
176006993 |
BG769410 |
26262 |
5q35.3 |
Hs.532129 |
6 |
ubiquitin ligase complex ubiquitin-protein ligase activity protein binding membrane integral to membrane protein ubiquitination |
|
1558459_s_at |
LOC401320 |
hypothetical LOC401320 |
7 |
|
BC041636 |
401320 |
7p15.1 |
Hs.561708 |
2 |
|
|
234130_at |
LDB3 |
LIM domain binding 3 |
10 |
88418300, 88418405, 88418405 |
AL359621 |
11155 |
10q22.3-q23.2 |
Hs.657271 |
15 |
protein binding cytoplasm cytoskeleton zinc ion binding Z disc pseudopodium metal ion binding perinuclear region of cytoplasm |
|
215673_at |
-0.212 |
2.075 |
-2.660 |
1.765e-02 |
0.473 |
-3.037 |
TEF |
thyrotrophic embryonic factor |
22 |
40093337, 40107908 |
AB051442 |
7008 |
22q13 22q13.2 |
Hs.181159 |
14 |
transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity rhythmic process |
|
226090_x_at |
RABL3 |
RAB, member of RAS oncogene family-like 3 |
3 |
-121888217 |
AK025772 |
285282 |
3q13.33 |
Hs.444360 |
1 |
nucleotide binding GTP binding intracellular small GTPase mediated signal transduction |
|
218789_s_at |
0.558 |
7.206 |
3.676 |
2.203e-03 |
0.276 |
-1.269 |
C11orf71 |
chromosome 11 open reading frame 71 |
11 |
-113767379 |
NM_019021 |
54494 |
11q14.2-q14.3 |
Hs.715083 |
3 |
|
|
238772_at |
ZNF207 |
zinc finger protein 207 |
17 |
27701269 |
BF055042 |
7756 |
17q11.2 |
Hs.500775 |
7 |
transcription factor activity intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
1562303_at |
ZKSCAN3 |
zinc finger with KRAB and SCAN domains 3 |
6 |
28425669 |
AK091225 |
80317 |
6p22.1 |
Hs.485004 |
11 |
transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
242215_at |
GRIK4 |
glutamate receptor, ionotropic, kainate 4 |
11 |
120036237 |
AI699933 |
2900 |
11q22.3 |
Hs.568901 |
14 |
receptor activity ion channel activity extracellular-glutamate-gated ion channel activity protein binding membrane fraction plasma membrane integral to plasma membrane ion transport glutamate signaling pathway synaptic transmission kainate selective glutamate receptor activity cell junction kainate selective glutamate receptor complex presynaptic membrane synapse postsynaptic membrane |
Neuroactive ligand-receptor interaction |
218159_at |
DDRGK1 |
DDRGK domain containing 1 |
20 |
-3119011 |
NM_023935 |
65992 |
20p13 |
Hs.471975 |
4 |
protein binding extracellular region |
|
239325_at |
LOC729723 |
hypothetical LOC729723 |
2 |
|
AW291033 |
729723 |
2p23.3 |
Hs.436366 |
|
|
|
238856_s_at |
PANK2 |
pantothenate kinase 2 |
20 |
3817485, 3817741, 3818462 |
BG108346 |
80025 |
20p13 |
Hs.516859 |
33 |
nucleotide binding pantothenate kinase activity protein binding ATP binding cytoplasm mitochondrion coenzyme A biosynthetic process transferase activity |
Pantothenate and CoA biosynthesis Metabolic pathways |
201545_s_at |
0.317 |
6.402 |
2.400 |
2.961e-02 |
0.536 |
-3.471 |
PABPN1 |
poly(A) binding protein, nuclear 1 |
14 |
22859236 |
NM_004643 |
8106 |
14q11.2-q13 |
Hs.707712 |
42 |
nucleotide binding nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus nucleoplasm nucleolus cytoplasm muscle contraction poly(A)+ mRNA export from nucleus |
|
228236_at |
C20orf54 |
chromosome 20 open reading frame 54 |
20 |
-688723 |
AA903862 |
113278 |
20p13 |
Hs.283865 |
6 |
membrane integral to membrane |
|
202792_s_at |
SAPS2 |
SAPS domain family, member 2 |
22 |
49128625 |
NM_014678 |
9701 |
22q13.33 |
Hs.449098 Hs.710221 |
8 |
protein binding cytoplasm |
|
1560001_at |
LOC100131581 |
hypothetical LOC100131581 |
8 |
|
AK092544 |
100131581 |
8p23.1 |
Hs.638992 |
1 |
|
|
1555559_s_at |
USP25 |
ubiquitin specific peptidase 25 |
21 |
16024366 |
AF419247 |
29761 |
21q11.2 |
Hs.473370 |
11 |
ubiquitin thiolesterase activity ubiquitin-specific protease activity protein modification process proteolysis ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity |
|
204747_at |
IFIT3 |
interferon-induced protein with tetratricopeptide repeats 3 |
10 |
91077581, 91082218 |
NM_001549 |
3437 |
10q24 |
Hs.714337 |
14 |
binding cellular_component biological_process |
|
228573_at |
0.895 |
5.054 |
3.763 |
1.839e-03 |
0.270 |
-1.116 |
ANTXR2 |
anthrax toxin receptor 2 |
4 |
-81117685, -81041796 |
BE673665 |
118429 |
4q21.21 |
Hs.162963 |
22 |
receptor activity protein binding extracellular region endoplasmic reticulum plasma membrane integral to membrane metal ion binding |
|
209860_s_at |
0.359 |
9.710 |
2.140 |
4.896e-02 |
0.590 |
-3.886 |
ANXA7 |
annexin A7 |
10 |
-74805194 |
J04543 |
310 |
10q21.1-q21.2 |
Hs.631827 |
24 |
calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding |
|
237247_at |
USP51 |
ubiquitin specific peptidase 51 |
X |
-55529686 |
AI341140 |
158880 |
Xp11.21 |
Hs.134289 |
9 |
ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity zinc ion binding metal ion binding |
|
209672_s_at |
MIOS |
missing oocyte, meiosis regulator, homolog (Drosophila) |
7 |
7573140 |
AL136892 |
54468 |
7p22-p21 |
Hs.520215 |
4 |
|
|
211181_x_at |
RUNX1 |
runt-related transcription factor 1 |
21 |
-35115443, -35081967, -35081967 |
AF312386 |
861 |
21q22.3 |
Hs.149261 Hs.612648 |
256 |
transcription factor activity protein binding ATP binding nucleus nucleus regulation of transcription, DNA-dependent multicellular organismal development transcription activator activity positive regulation of granulocyte differentiation chloride ion binding positive regulation of angiogenesis positive regulation of transcription from RNA polymerase II promoter |
Pathways in cancer Chronic myeloid leukemia Acute myeloid leukemia |
1552626_a_at |
TMEM163 |
transmembrane protein 163 |
2 |
-134929800 |
NM_030923 |
81615 |
2q21.3 |
Hs.369471 Hs.595089 |
5 |
membrane integral to membrane |
|
224079_at |
IL17C |
interleukin 17C |
16 |
87232501 |
AF152099 |
27189 |
16q24 |
Hs.278911 |
5 |
cytokine activity extracellular region extracellular space soluble fraction inflammatory response cell surface receptor linked signal transduction cell-cell signaling neutrophil differentiation |
|
227413_at |
UBLCP1 |
ubiquitin-like domain containing CTD phosphatase 1 |
5 |
158622666 |
BF965546 |
134510 |
5q33.3 |
Hs.591733 |
7 |
phosphoprotein phosphatase activity nucleus hydrolase activity |
|
227408_s_at |
SNX25 |
sorting nexin 25 |
4 |
186368277 |
AW008976 |
83891 |
4q35.1 |
Hs.369091 |
4 |
signal transducer activity protein binding cell communication protein transport phosphoinositide binding |
|
224303_x_at |
NIN |
ninein (GSK3B interacting protein) |
14 |
-50263700, -50262296, -50262296, -50256230 |
AF223938 |
51199 |
14q22.1 |
Hs.310429 |
23 |
nucleotide binding protein binding GTP binding centrosome microtubule centrosome localization |
|
209909_s_at |
0.890 |
2.853 |
2.622 |
1.907e-02 |
0.489 |
-3.102 |
TGFB2 |
transforming growth factor, beta 2 |
1 |
216586013 |
M19154 |
7042 |
1q41 |
Hs.133379 |
112 |
cell morphogenesis skeletal system development cartilage condensation angiogenesis beta-amyloid binding blood vessel development eye development response to hypoxia blood vessel remodeling receptor signaling protein serine/threonine kinase activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding cytokine activity extracellular region extracellular region extracellular region extracellular space induction of apoptosis activation-induced cell death of T cells cell cycle arrest transforming growth factor beta receptor signaling pathway SMAD protein nuclear translocation cell-cell signaling axon guidance salivary gland morphogenesis growth factor activity cell death positive regulation of cell proliferation glial cell migration embryonic development positive regulation of epithelial cell migration negative regulation of alkaline phosphatase activity positive regulation of epithelial to mesenchymal transition positive regulation of phosphoinositide 3-kinase cascade menstrual cycle phase hemopoiesis collagen fibril organization positive regulation of cell growth negative regulation of cell growth axon neutrophil chemotaxis neutrophil chemotaxis extracellular matrix hair follicle morphogenesis platelet alpha granule lumen activation of protein kinase activity response to progesterone stimulus positive regulation of stress-activated MAPK cascade regulation of transforming growth factor-beta2 production positive regulation of cell adhesion mediated by integrin wound healing dopamine biosynthetic process odontogenesis protein homodimerization activity cell soma positive regulation of neuron apoptosis cell-cell junction organization positive regulation of integrin biosynthetic process positive regulation of ossification positive regulation of cell cycle positive regulation of heart contraction protein heterodimerization activity somatic stem cell division neuron fate commitment neuron development generation of neurons negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive regulation of protein secretion negative regulation of immune response positive regulation of immune response positive regulation of catagen positive regulation of cardioblast differentiation cardiac muscle cell proliferation cardiac epithelial to mesenchymal transition pathway-restricted SMAD protein phosphorylation |
MAPK signaling pathway Cytokine-cytokine receptor interaction Cell cycle TGF-beta signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Chronic myeloid leukemia Hypertrophic cardiomyopathy (HCM) |
208373_s_at |
-0.321 |
5.275 |
-3.197 |
5.917e-03 |
0.357 |
-2.110 |
P2RY6 |
pyrimidinergic receptor P2Y, G-protein coupled, 6 |
11 |
72653217, 72658586, 72660894 |
NM_004154 |
5031 |
11q13.5 |
Hs.16362 |
23 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger transepithelial chloride transport purinergic nucleotide receptor activity, G-protein coupled UDP-activated nucleotide receptor activity |
Neuroactive ligand-receptor interaction |
214906_x_at |
N4BP2L1 |
NEDD4 binding protein 2-like 1 |
13 |
-31872859 |
AL049786 |
90634 |
13q12-q13 |
Hs.161220 |
2 |
|
|
237044_s_at |
C10orf41 |
chromosome 10 open reading frame 41 |
10 |
76831291, 76833519 |
AI480142 |
100131213 |
10q22.2 |
Hs.534598 Hs.599628 |
4 |
|
|
211818_s_at |
-0.307 |
5.992 |
-2.504 |
2.413e-02 |
0.510 |
-3.300 |
PDE4C |
phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila) |
19 |
-18179770, -18179770, -18179770 |
U88712 |
5143 |
19p13.11 |
Hs.132584 |
13 |
3',5'-cyclic-AMP phosphodiesterase activity signal transduction hydrolase activity |
Purine metabolism |
1557211_a_at |
0.402 |
3.385 |
2.374 |
3.116e-02 |
0.543 |
-3.513 |
C14orf86 |
chromosome 14 open reading frame 86 |
14 |
-93440828 |
BC037859 |
283592 |
14q32.12 |
Hs.585649 |
1 |
|
|
231454_at |
PLAC4 |
placenta-specific 4 |
21 |
-41469027 |
R31094 |
191585 |
21q22.2 |
Hs.472492 |
3 |
|
|
220634_at |
TBX4 |
T-box 4 |
17 |
56888588 |
NM_018488 |
9496 |
17q21-q22 |
Hs.143907 |
7 |
angiogenesis morphogenesis of an epithelium transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development lung development embryonic limb morphogenesis leg morphogenesis skeletal system morphogenesis |
|
233078_at |
API5 |
apoptosis inhibitor 5 |
11 |
43290080 |
AK021649 |
8539 |
11p11.2 |
Hs.435771 |
15 |
binding nucleus spliceosomal complex cytoplasm apoptosis anti-apoptosis anti-apoptosis anti-apoptosis fibroblast growth factor binding |
|
205656_at |
PCDH17 |
protocadherin 17 |
13 |
57103789 |
NM_014459 |
27253 |
13q21.1 |
Hs.106511 |
11 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane |
|
214718_at |
GATAD1 |
GATA zinc finger domain containing 1 |
7 |
91914700 |
AK026142 |
57798 |
7q21-q22 |
Hs.21145 |
6 |
transcription factor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding |
|
212922_s_at |
SMYD2 |
SET and MYND domain containing 2 |
1 |
212521187 |
AI809870 |
56950 |
1q32.3-q41 |
Hs.66170 |
11 |
protein binding zinc ion binding metal ion binding |
|
212967_x_at |
NAP1L1 |
nucleosome assembly protein 1-like 1 |
12 |
-74724938 |
AW148801 |
4673 |
12q21.2 |
Hs.524599 Hs.695185 |
17 |
protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome |
|
225288_at |
COL27A1 |
collagen, type XXVII, alpha 1 |
9 |
115958051 |
AI949136 |
85301 |
9q32 |
Hs.494892 |
8 |
extracellular matrix structural constituent extracellular region collagen cell adhesion |
|
211072_x_at |
0.483 |
10.538 |
2.337 |
3.354e-02 |
0.552 |
-3.574 |
TUBA1B |
tubulin, alpha 1b |
12 |
-47807832 |
BC006481 |
10376 |
12q13.12 |
Hs.524390 Hs.719075 |
42 |
nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
235695_at |
INPP4A |
inositol polyphosphate-4-phosphatase, type I, 107kDa |
2 |
98427752, 98427752 |
AI051236 |
3631 |
2q11.2 |
Hs.469386 |
16 |
signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system |
217924_at |
C6orf106 |
chromosome 6 open reading frame 106 |
6 |
-34663047 |
AL523965 |
64771 |
6p21.31 |
Hs.643498 |
10 |
|
|
208809_s_at |
0.353 |
8.603 |
2.496 |
2.451e-02 |
0.513 |
-3.313 |
C6orf62 |
chromosome 6 open reading frame 62 |
6 |
-24813069 |
AL136632 |
81688 |
6p22.3 |
Hs.519930 |
6 |
molecular_function cellular_component intracellular biological_process |
|
204807_at |
TMEM5 |
transmembrane protein 5 |
12 |
62459903 |
BF224146 |
10329 |
12q14.2 |
Hs.216386 |
3 |
integral to plasma membrane membrane |
|
219939_s_at |
CSDE1 |
cold shock domain containing E1, RNA-binding |
1 |
-115061060, -115061060, -115061059 |
NM_007158 |
7812 |
1p22 |
Hs.69855 |
25 |
DNA binding RNA binding protein binding cytoplasm regulation of transcription, DNA-dependent male gonad development |
|
201533_at |
CTNNB1 |
catenin (cadherin-associated protein), beta 1, 88kDa |
3 |
41215945 |
NM_001904 |
1499 |
3p21 |
Hs.476018 |
680 |
negative regulation of transcription from RNA polymerase II promoter skeletal system development patterning of blood vessels gastrulation with mouth forming second endoderm formation cell fate specification endodermal cell fate commitment epithelial to mesenchymal transition chromatin binding double-stranded DNA binding transcription factor activity transcription coactivator activity signal transducer activity membrane fraction nucleus transcription factor complex cytoplasm centrosome cytosol cytoskeleton plasma membrane fascia adherens apoptosis cell-matrix adhesion synaptic transmission ectoderm development glial cell fate determination heart development protein C-terminus binding transcription factor binding anterior/posterior axis specification dorsal/ventral axis specification proximal/distal pattern formation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process basolateral plasma membrane lateral plasma membrane morphogenesis of embryonic epithelium cell-cell adhesion catenin complex kinase binding protein phosphatase binding Z disc lamellipodium hemopoiesis lung development androgen receptor signaling pathway positive regulation of epithelial cell differentiation beta-catenin destruction complex forebrain development regulation of centriole-centriole cohesion pancreas development microvillus membrane negative regulation of chondrocyte differentiation T cell differentiation in the thymus cellular protein localization Axin-APC-beta-catenin-GSK3B complex embryonic hindlimb morphogenesis embryonic arm morphogenesis regulation of cell proliferation odontogenesis of dentine-containing tooth embryonic digit morphogenesis apical junction complex positive regulation of MAPKKK cascade apical part of cell alpha-catenin binding cadherin binding bone resorption positive regulation of osteoblast differentiation negative regulation of osteoclast differentiation cell maturation synaptic vesicle transport thymus development camera-type eye morphogenesis androgen receptor binding synapse organization Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex I-SMAD binding |
Wnt signaling pathway Focal adhesion Adherens junction Tight junction Leukocyte transendothelial migration Melanogenesis Pathogenic Escherichia coli infection - EHEC Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
1552491_at |
IDI2 |
isopentenyl-diphosphate delta isomerase 2 |
10 |
-1054846 |
NM_033261 |
91734 |
10p15.3 |
Hs.591325 Hs.9270 |
6 |
magnesium ion binding isopentenyl-diphosphate delta-isomerase activity peroxisome cytosol cholesterol biosynthetic process isoprenoid biosynthetic process carotenoid biosynthetic process hydrolase activity isomerase activity |
Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
232265_at |
-0.276 |
4.381 |
-2.174 |
4.591e-02 |
0.581 |
-3.834 |
ATXN7L1 |
ataxin 7-like 1 |
7 |
-105187871, -105032456, -105032456 |
BC003517 |
222255 |
7q22.3 |
Hs.489603 |
8 |
|
|
228187_at |
GAS1 |
growth arrest-specific 1 |
9 |
-88749096 |
AI161237 |
2619 |
9q21.3-q22 |
Hs.65029 |
17 |
positive regulation of mesenchymal cell proliferation molecular_function protein binding plasma membrane cell cycle cell cycle arrest axon guidance programmed cell death cerebellum morphogenesis dorsal/ventral neural tube patterning outer ear morphogenesis middle ear morphogenesis embryonic digit morphogenesis regulation of apoptosis camera-type eye development cell fate commitment negative regulation of S phase of mitotic cell cycle negative regulation of smoothened signaling pathway positive regulation of smoothened signaling pathway anchored to plasma membrane developmental growth eye morphogenesis embryonic cranial skeleton morphogenesis embryonic skeletal system development positive regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation palate development |
Hedgehog signaling pathway |
204177_s_at |
KLHL20 |
kelch-like 20 (Drosophila) |
1 |
171950702 |
NM_014458 |
27252 |
1q24.1-q24.3 |
Hs.495035 |
10 |
actin binding protein binding cytoskeleton organization cell surface actin cytoskeleton modification-dependent protein catabolic process |
|
225492_at |
0.527 |
7.533 |
2.653 |
1.792e-02 |
0.475 |
-3.050 |
TMEM33 |
transmembrane protein 33 |
4 |
41631893 |
BG500396 |
55161 |
4p13 |
Hs.31082 |
5 |
protein binding biological_process membrane integral to membrane melanosome |
|
203612_at |
BYSL |
bystin-like |
6 |
41996942 |
NM_004053 |
705 |
6p21.1 |
Hs.106880 |
10 |
nucleus nucleolus cytoplasm cell adhesion female pregnancy ribosome biogenesis |
|
213172_at |
0.430 |
3.701 |
2.136 |
4.937e-02 |
0.590 |
-3.893 |
TTC9 |
tetratricopeptide repeat domain 9 |
14 |
70178256 |
AW235608 |
23508 |
14q24.2 |
Hs.79170 |
5 |
binding protein folding |
|
201068_s_at |
PSMC2 |
proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
7 |
102775324 |
NM_002803 |
5701 |
7q22.1-q22.3 |
Hs.437366 |
56 |
nucleotide binding proteasome complex protein binding ATP binding nucleus cytoplasm cytosol ubiquitin-dependent protein catabolic process hydrolase activity ATPase activity protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process interspecies interaction between organisms negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
222401_s_at |
0.477 |
8.202 |
3.359 |
4.237e-03 |
0.326 |
-1.826 |
TMEM50A |
transmembrane protein 50A |
1 |
25537397 |
AL550722 |
23585 |
1p36.11 |
Hs.523054 |
13 |
cytoplasm endoplasmic reticulum membrane integral to membrane |
|
226452_at |
PDK1 |
pyruvate dehydrogenase kinase, isozyme 1 |
2 |
173129024 |
AU146532 |
5163 |
2q31.1 |
Hs.470633 |
52 |
two-component sensor activity nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrial matrix carbohydrate metabolic process glucose metabolic process signal transduction small GTPase mediated signal transduction transferase activity peptidyl-histidine phosphorylation |
T cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway |
212764_at |
ZEB1 |
zinc finger E-box binding homeobox 1 |
10 |
31647429, 31647717, 31647752, 31648106, 31650069 |
AI806174 |
6935 |
10p11.2 |
Hs.124503 |
52 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity transcription coactivator activity transcription corepressor activity intracellular nucleus immune response zinc ion binding cell proliferation sequence-specific DNA binding metal ion binding |
|
223104_at |
JAGN1 |
jagunal homolog 1 (Drosophila) |
3 |
9907270 |
AF212230 |
84522 |
3p25.2 |
Hs.24054 |
6 |
endoplasmic reticulum membrane integral to membrane |
|
214088_s_at |
-0.186 |
5.204 |
-2.270 |
3.816e-02 |
0.565 |
-3.681 |
FUT3 |
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
19 |
-5793898 |
AW080549 |
2525 |
19p13.3 |
Hs.169238 |
55 |
membrane fraction Golgi apparatus carbohydrate metabolic process protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity |
Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
218095_s_at |
TMEM165 |
transmembrane protein 165 |
4 |
55956846 |
NM_018475 |
55858 |
4q12 |
Hs.479766 |
6 |
membrane integral to membrane |
|
218835_at |
SFTPA2 |
surfactant protein A2 |
10 |
-81305558, -80985613 |
NM_006926 |
729238 |
10q22.3 |
Hs.523084 Hs.719155 |
17 |
binding calcium ion binding sugar binding extracellular region proteinaceous extracellular matrix extracellular space respiratory gaseous exchange regulation of liquid surface tension |
|
232902_s_at |
0.404 |
5.887 |
2.822 |
1.273e-02 |
0.431 |
-2.761 |
RARS2 |
arginyl-tRNA synthetase 2, mitochondrial |
6 |
-88280815 |
BG165118 |
57038 |
6q16.1 |
Hs.485910 |
8 |
nucleotide binding arginine-tRNA ligase activity protein binding ATP binding cytoplasm mitochondrion mitochondrial matrix arginyl-tRNA aminoacylation ligase activity |
Aminoacyl-tRNA biosynthesis |
203912_s_at |
DNASE1L1 |
deoxyribonuclease I-like 1 |
X |
-153282772, -153282772 |
NM_006730 |
1774 |
Xq28 |
Hs.401929 |
14 |
DNA binding endonuclease activity deoxyribonuclease activity endoplasmic reticulum DNA catabolic process hydrolase activity |
|
220372_at |
0.498 |
4.325 |
2.786 |
1.371e-02 |
0.440 |
-2.823 |
DNAJC28 |
DnaJ (Hsp40) homolog, subfamily C, member 28 |
21 |
-33782107, -33782107 |
NM_017833 |
54943 |
21q22.11 |
Hs.458308 |
8 |
heat shock protein binding |
|
202708_s_at |
HIST2H2BE |
histone cluster 2, H2be |
1 |
-148122633 |
NM_003528 |
8349 |
1q21-q23 |
Hs.2178 |
50 |
nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly defense response to bacterium |
Systemic lupus erythematosus |
228935_at |
SLC4A8 |
solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
12 |
50104860, 50104860 |
AI570494 |
9498 |
12q13.13 |
Hs.370636 |
13 |
transporter activity inorganic anion exchanger activity sodium ion transport anion transport anion transmembrane transporter activity antiporter activity membrane integral to membrane sodium ion binding |
|
205406_s_at |
SPA17 |
sperm autoantigenic protein 17 |
11 |
124048949 |
NM_017425 |
53340 |
11q24.2 |
Hs.286233 |
19 |
signal transduction spermatogenesis single fertilization binding of sperm to zona pellucida cAMP-dependent protein kinase regulator activity membrane |
|
232836_at |
-0.301 |
5.423 |
-2.494 |
2.459e-02 |
0.513 |
-3.316 |
C20orf61 |
chromosome 20 open reading frame 61 |
20 |
|
AL080274 |
728450 |
20p12.2 |
|
2 |
|
|
232910_at |
-0.342 |
4.339 |
-3.200 |
5.881e-03 |
0.357 |
-2.105 |
NCRNA00081 |
non-protein coding RNA 81 |
10 |
-112648478, -112648478 |
AK021501 |
92482 |
10q25.2 |
Hs.232543 Hs.651480 |
4 |
cytoplasm cilium |
|
205746_s_at |
0.315 |
4.163 |
2.460 |
2.632e-02 |
0.521 |
-3.372 |
ADAM17 |
ADAM metallopeptidase domain 17 |
2 |
-9546861 |
U86755 |
6868 |
2p25 |
Hs.404914 |
121 |
response to hypoxia positive regulation of protein amino acid phosphorylation neutrophil mediated immunity germinal center formation metalloendopeptidase activity interleukin-6 receptor binding integrin binding protein binding cytoplasm integral to plasma membrane cell-cell junction focal adhesion proteolysis epidermal growth factor receptor signaling pathway Notch signaling pathway peptidase activity zinc ion binding positive regulation of cell proliferation response to bacterium cell surface positive regulation of T cell chemotaxis actin cytoskeleton membrane apical plasma membrane SH3 domain binding PDZ domain binding B cell differentiation positive regulation of cell growth positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of cyclin-dependent protein kinase activity during G1/S response to lipopolysaccharide ruffle membrane negative regulation of interleukin-8 production positive regulation of chemokine production regulation of mast cell apoptosis T cell differentiation in the thymus cell adhesion mediated by integrin wound healing, spreading of epidermal cells response to drug membrane raft positive regulation of epidermal growth factor receptor activity metal ion binding spleen development cell motility PMA-inducible membrane protein ectodomain proteolysis response to high density lipoprotein stimulus |
Notch signaling pathway Alzheimer's disease Epithelial cell signaling in Helicobacter pylori infection |
201069_at |
0.733 |
6.784 |
3.668 |
2.237e-03 |
0.276 |
-1.282 |
MMP2 |
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
16 |
54070581, 54072974 |
NM_004530 |
4313 |
16q13-q21 |
Hs.513617 |
587 |
response to hypoxia blood vessel maturation intramembranous ossification metalloendopeptidase activity calcium ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space plasma membrane proteolysis metabolic process peptidase activity zinc ion binding sarcomere collagen catabolic process intracellular membrane-bounded organelle face morphogenesis bone trabecula formation |
Leukocyte transendothelial migration GnRH signaling pathway Pathways in cancer Bladder cancer |
226168_at |
0.273 |
6.754 |
2.464 |
2.609e-02 |
0.519 |
-3.365 |
ZFAND2B |
zinc finger, AN1-type domain 2B |
2 |
219779781 |
AA524690 |
130617 |
2q35 |
Hs.534540 |
6 |
protein binding zinc ion binding metal ion binding |
|
237227_at |
NEK10 |
NIMA (never in mitosis gene a)- related kinase 10 |
3 |
-27232101 |
AI652681 |
152110 |
3p24.1 |
Hs.506115 |
4 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding kinase activity transferase activity |
|
236073_at |
-0.209 |
5.254 |
-2.220 |
4.204e-02 |
0.575 |
-3.761 |
EPHA10 |
EPH receptor A10 |
1 |
-37998531, -37954232 |
AA789266 |
284656 |
1p34.3 |
Hs.129435 |
5 |
nucleotide binding receptor activity ephrin receptor activity ATP binding extracellular region plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane transferase activity |
|
206752_s_at |
DFFB |
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
1 |
3763704 |
NM_004402 |
1677 |
1p36.3 |
Hs.133089 |
40 |
DNA binding nicotinate phosphoribosyltransferase activity nuclease activity caspase-activated deoxyribonuclease activity intracellular nucleus nucleoplasm cytoplasm cytosol DNA fragmentation involved in apoptosis apoptosis intracellular signaling cascade hydrolase activity enzyme binding apoptotic chromosome condensation |
Apoptosis |
203798_s_at |
VSNL1 |
visinin-like 1 |
2 |
17585287 |
NM_003385 |
7447 |
2p24.3 |
Hs.444212 |
29 |
calcium ion binding |
|
211950_at |
UBR4 |
ubiquitin protein ligase E3 component n-recognin 4 |
1 |
-19273586 |
AB007931 |
23352 |
1p36.13 |
Hs.148078 Hs.649405 |
11 |
ubiquitin-protein ligase activity calmodulin binding nucleus cytoplasm cytoskeleton zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process interspecies interaction between organisms metal ion binding |
|
202816_s_at |
SS18 |
synovial sarcoma translocation, chromosome 18 |
18 |
-21850214 |
AW292882 |
6760 |
18q11.2 |
Hs.404263 |
32 |
nucleus |
|
219828_at |
C9orf86 |
chromosome 9 open reading frame 86 |
9 |
138822201 |
NM_024718 |
55684 |
9q34.3 |
Hs.370555 |
11 |
nucleotide binding protein binding GTP binding nucleus cytoplasm small GTPase mediated signal transduction |
|
224996_at |
0.546 |
5.867 |
2.616 |
1.932e-02 |
0.489 |
-3.113 |
ASPH |
aspartate beta-hydroxylase |
8 |
-62739837, -62699648, -62699648, -62575669 |
N30209 |
444 |
8q12.1 |
Hs.591874 |
24 |
peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis |
|
204881_s_at |
UGCG |
UDP-glucose ceramide glucosyltransferase |
9 |
113699026 |
NM_003358 |
7357 |
9q31 |
Hs.304249 Hs.593014 |
20 |
membrane fraction endoplasmic reticulum sphingolipid metabolic process glucosylceramide biosynthetic process ceramide glucosyltransferase activity epidermis development lipid biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups |
Sphingolipid metabolism Metabolic pathways |
203757_s_at |
CEACAM6 |
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
19 |
46951237 |
BC005008 |
4680 |
19q13.2 |
Hs.466814 |
45 |
plasma membrane plasma membrane integral to plasma membrane signal transduction cell-cell signaling anchored to membrane |
|
215999_at |
CDRT1 |
CMT1A duplicated region transcript 1 |
17 |
-15432701 |
U43383 |
374286 |
17p12 |
Hs.548021 Hs.632233 |
7 |
molecular_function cellular_component biological_process |
|
214050_at |
CGGBP1 |
CGG triplet repeat binding protein 1 |
3 |
-88183789 |
AI694317 |
8545 |
3p12-p11.1 |
Hs.444818 |
14 |
DNA binding double-stranded DNA binding nucleus regulation of transcription |
|
203349_s_at |
1.015 |
5.794 |
4.041 |
1.039e-03 |
0.225 |
-0.632 |
ETV5 |
ets variant 5 |
3 |
-187246799 |
NM_004454 |
2119 |
3q28 |
Hs.43697 |
21 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
223126_s_at |
C1orf21 |
chromosome 1 open reading frame 21 |
1 |
182622772 |
AI159874 |
81563 |
1q25 |
Hs.497159 Hs.719188 |
8 |
|
|
235882_at |
VPS53 |
vacuolar protein sorting 53 homolog (S. cerevisiae) |
17 |
-382282, -361479 |
BF115777 |
55275 |
17p13.3 |
Hs.461819 |
11 |
endosome Golgi apparatus protein transport membrane |
|
215910_s_at |
-0.255 |
3.823 |
-2.769 |
1.420e-02 |
0.446 |
-2.853 |
FNDC3A |
fibronectin type III domain containing 3A |
13 |
48448048, 48582449 |
AL137000 |
22862 |
13q14.2 |
Hs.508010 |
10 |
acrosomal vesicle Golgi apparatus cytosol spermatid development fertilization vesicle membrane cell-cell adhesion cytoplasmic vesicle vesicular fraction Sertoli cell development |
|
221568_s_at |
LIN7C |
lin-7 homolog C (C. elegans) |
11 |
-27472546 |
AF090900 |
55327 |
11p14 |
Hs.693840 Hs.91393 |
16 |
protein binding plasma membrane tight junction exocytosis neurotransmitter secretion protein transport synaptosome cell junction synapse postsynaptic membrane |
|
202484_s_at |
0.435 |
7.103 |
3.202 |
5.858e-03 |
0.357 |
-2.101 |
MBD2 |
methyl-CpG binding domain protein 2 |
18 |
-49983044, -49934572 |
AF072242 |
8932 |
18q21 |
Hs.25674 |
50 |
histone deacetylase complex negative regulation of transcription from RNA polymerase II promoter heterochromatin DNA binding chromatin binding satellite DNA binding mRNA binding nucleus nucleus cytoplasm methyl-CpG binding negative regulation of transcription transcription repressor activity positive regulation of Wnt receptor signaling pathway siRNA binding regulation of cell proliferation maternal behavior cellular protein complex assembly C2H2 zinc finger domain binding |
|
224851_at |
CDK6 |
cyclin-dependent kinase 6 |
7 |
-92072172, -92072172 |
AW274756 |
1021 |
7q21-q22 |
Hs.119882 |
95 |
G1 phase of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex ruffle positive regulation of cell-matrix adhesion cyclin-dependent protein kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation regulation of gene expression regulation of gene expression transferase activity hemopoiesis cyclin binding gliogenesis cell dedifferentiation regulation of erythrocyte differentiation negative regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of fibroblast proliferation negative regulation of epithelial cell proliferation cell division |
Cell cycle p53 signaling pathway Pathways in cancer Pancreatic cancer Glioma Melanoma Chronic myeloid leukemia Small cell lung cancer Non-small cell lung cancer |
38691_s_at |
SFTPC |
surfactant protein C |
8 |
22075128 |
J03553 |
6440 |
8p21 |
Hs.1074 |
68 |
extracellular region extracellular space respiratory gaseous exchange regulation of liquid surface tension |
|
219812_at |
PVRIG |
poliovirus receptor related immunoglobulin domain containing |
7 |
99654806 |
NM_024070 |
79037 |
7q22.1 |
Hs.521075 |
4 |
membrane integral to membrane |
|
243547_at |
FLJ39639 |
hypothetical protein FLJ39639 |
16 |
|
BE176531 |
283876 |
16p13.3 |
Hs.592092 |
2 |
|
|
221748_s_at |
0.353 |
10.280 |
2.317 |
3.485e-02 |
0.555 |
-3.606 |
TNS1 |
tensin 1 |
2 |
-218372756 |
AL046979 |
7145 |
2q35-q36 |
Hs.471381 |
16 |
actin binding protein binding cytoplasm cytoskeleton focal adhesion cell junction |
|
232366_at |
KIAA0232 |
KIAA0232 |
4 |
6835359 |
AF143884 |
9778 |
4p16.1 |
Hs.79276 |
7 |
nucleotide binding ATP binding |
|
220048_at |
EDAR |
ectodysplasin A receptor |
2 |
-108877358 |
NM_022336 |
10913 |
2q11-q13 |
Hs.171971 |
23 |
hair follicle development transmembrane receptor activity protein binding plasma membrane apoptosis signal transduction multicellular organismal development salivary gland development integral to membrane cell differentiation positive regulation of NF-kappaB import into nucleus odontogenesis of dentine-containing tooth pigmentation apical part of cell |
Cytokine-cytokine receptor interaction |
221489_s_at |
SPRY4 |
sprouty homolog 4 (Drosophila) |
5 |
-141670175 |
W48843 |
81848 |
5q31.3 |
Hs.323308 |
14 |
protein binding cytoplasm plasma membrane multicellular organismal development regulation of signal transduction cell projection negative regulation of MAP kinase activity |
Jak-STAT signaling pathway |
1554129_a_at |
ADIG |
adipogenin |
20 |
36643251 |
BC029594 |
149685 |
20q11.23 |
Hs.368028 |
3 |
nucleus cytoplasm membrane integral to membrane positive regulation of fat cell differentiation white fat cell differentiation brown fat cell differentiation |
|
201258_at |
-0.401 |
11.844 |
-2.344 |
3.308e-02 |
0.551 |
-3.563 |
RPS16 |
ribosomal protein S16 |
19 |
-44615686 |
NM_001020 |
6217 |
19q13.1 |
Hs.397609 |
24 |
RNA binding structural constituent of ribosome protein binding intracellular cytosol ribosome rRNA processing translational elongation cytosolic small ribosomal subunit cytosolic small ribosomal subunit ribosomal small subunit biogenesis |
Ribosome |
212780_at |
SOS1 |
son of sevenless homolog 1 (Drosophila) |
2 |
-39062193 |
AA700167 |
6654 |
2p22-p21 |
Hs.709893 |
107 |
DNA binding Rho guanyl-nucleotide exchange factor activity Rho GTPase activator activity protein binding intracellular cytosol plasma membrane signal transduction Ras protein signal transduction Ras protein signal transduction postsynaptic density SH3 domain binding regulation of Rho protein signal transduction cell soma positive regulation of epidermal growth factor receptor signaling pathway nerve growth factor receptor signaling pathway regulation of small GTPase mediated signal transduction |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway Dorso-ventral axis formation Focal adhesion Gap junction Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway GnRH signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Endometrial cancer Glioma Prostate cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
236924_at |
GLMN |
glomulin, FKBP associated protein |
1 |
-92484542 |
AA814383 |
11146 |
1p22.1 |
Hs.49105 |
14 |
vasculogenesis hepatocyte growth factor receptor binding protein binding protein binding intracellular regulation of gene expression, epigenetic negative regulation of T cell proliferation positive regulation of phosphorylation muscle cell differentiation positive regulation of interleukin-2 biosynthetic process positive regulation of cytokine secretion |
|
224520_s_at |
1.600 |
6.695 |
4.280 |
6.389e-04 |
0.211 |
-0.223 |
BEST3 |
bestrophin 3 |
12 |
-68333655, -68333655 |
BC006440 |
144453 |
12q14.2-q15 |
Hs.280782 |
7 |
molecular_function ion channel activity chloride channel activity calcium ion binding plasma membrane ion transport biological_process integral to membrane chloride ion binding chloride channel complex |
|
213145_at |
FBXL14 |
F-box and leucine-rich repeat protein 14 |
12 |
-1545420 |
BF001666 |
144699 |
12p13.33 |
Hs.367956 |
3 |
modification-dependent protein catabolic process |
|
235086_at |
-0.263 |
3.228 |
-2.291 |
3.664e-02 |
0.560 |
-3.648 |
THBS1 |
thrombospondin 1 |
15 |
37660571 |
AW956580 |
7057 |
15q15 |
Hs.164226 |
211 |
activation of MAPK activity response to hypoxia negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation fibronectin binding sprouting angiogenesis chronic inflammatory response negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II negative regulation of dendritic cell antigen processing and presentation integrin binding structural molecule activity calcium ion binding extracellular region extracellular region fibrinogen complex anti-apoptosis immune response cell cycle arrest cell adhesion heparin binding response to glucose stimulus external side of plasma membrane positive regulation of oxygen and reactive oxygen species metabolic process negative regulation of plasma membrane long-chain fatty acid transport negative regulation of nitric oxide mediated signal transduction negative regulation of cGMP-mediated signaling negative regulation of plasminogen activation positive regulation of macrophage chemotaxis positive regulation of fibroblast migration negative regulation of angiogenesis peptide cross-linking low-density lipoprotein binding positive regulation of blood coagulation positive regulation of transforming growth factor beta receptor signaling pathway extracellular matrix platelet alpha granule lumen response to magnesium ion response to progesterone stimulus negative regulation of interleukin-12 production positive regulation of transforming growth factor-beta1 production cellular response to heat negative regulation of fibroblast growth factor receptor signaling pathway positive regulation of phosphorylation identical protein binding positive regulation of macrophage activation laminin binding proteoglycan binding eukaryotic cell surface binding positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration engulfment of apoptotic cell positive regulation of translation positive regulation of angiogenesis fibroblast growth factor 2 binding transforming growth factor beta binding transforming growth factor beta binding positive regulation of chemotaxis response to calcium ion negative regulation of focal adhesion formation negative regulation of fibrinolysis fibrinogen binding collagen V binding |
p53 signaling pathway TGF-beta signaling pathway Focal adhesion ECM-receptor interaction Bladder cancer |
200878_at |
EPAS1 |
endothelial PAS domain protein 1 |
2 |
46378066 |
AF052094 |
2034 |
2p21-p16 |
Hs.468410 |
101 |
angiogenesis response to hypoxia embryonic placenta development blood vessel remodeling regulation of heart rate RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus transcription factor complex transcription factor complex cytoplasm regulation of transcription, DNA-dependent response to oxidative stress mitochondrion organization signal transduction multicellular organismal development visual perception transcription factor binding hemopoiesis cell differentiation erythrocyte differentiation lung development histone acetyltransferase binding norepinephrine metabolic process surfactant homeostasis sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity cell maturation |
Pathways in cancer Renal cell carcinoma |
31846_at |
-0.314 |
8.470 |
-2.980 |
9.223e-03 |
0.400 |
-2.487 |
RHOD |
ras homolog gene family, member D |
11 |
66580864 |
AW003733 |
29984 |
11q14.3 |
Hs.15114 |
22 |
nucleotide binding GTPase activity GTP binding intracellular plasma membrane small GTPase mediated signal transduction Rho protein signal transduction |
Axon guidance |
204903_x_at |
0.328 |
7.200 |
3.269 |
5.097e-03 |
0.346 |
-1.983 |
ATG4B |
ATG4 autophagy related 4 homolog B (S. cerevisiae) |
2 |
242225699, 54821 |
AL080168 |
23192 |
2q37.3 |
Hs.283610 |
19 |
protein binding cytoplasm microtubule associated complex proteolysis autophagy peptidase activity cysteine-type peptidase activity protein transport modification-dependent protein catabolic process |
Regulation of autophagy |
228311_at |
BCL6B |
B-cell CLL/lymphoma 6, member B (zinc finger protein) |
17 |
6867092 |
AI827455 |
255877 |
17p13.1 |
Hs.22575 |
8 |
negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding intracellular nucleus zinc ion binding transcription repressor activity metal ion binding |
|
202695_s_at |
0.667 |
3.819 |
3.356 |
4.257e-03 |
0.327 |
-1.830 |
STK17A |
serine/threonine kinase 17a |
7 |
43589216 |
NM_004760 |
9263 |
7p12-p14 |
Hs.709489 |
6 |
nucleotide binding protein serine/threonine kinase activity ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade transferase activity |
|
222478_at |
VPS36 |
vacuolar protein sorting 36 homolog (S. cerevisiae) |
13 |
-51884737 |
AL576924 |
51028 |
13q14.3 |
Hs.109520 |
11 |
nucleus cytoplasm lysosome late endosome lipid binding protein transport ubiquitin binding regulation of transcription |
Endocytosis |
234381_at |
IGLV4-3 |
immunoglobulin lambda variable 4-3 |
22 |
|
D87024 |
28786 |
22q11.2 |
Hs.449585 |
5 |
|
|
201551_s_at |
LAMP1 |
lysosomal-associated membrane protein 1 |
13 |
112999469 |
J03263 |
3916 |
13q34 |
Hs.494419 |
38 |
membrane fraction lysosome multivesicular body integral to plasma membrane external side of plasma membrane sarcolemma melanosome |
Lysosome |
235521_at |
-0.516 |
6.453 |
-3.323 |
4.560e-03 |
0.332 |
-1.888 |
HOXA3 |
homeobox A3 |
7 |
-27112333, -27112333, -27112333 |
AW137982 |
3200 |
7p15-p14 |
Hs.659337 |
18 |
blood vessel remodeling transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development positive regulation of cell proliferation anterior/posterior pattern formation specification of organ position glossopharyngeal nerve morphogenesis thyroid gland development sequence-specific DNA binding thymus development organ formation embryonic skeletal system morphogenesis cartilage development parathyroid gland development |
|
215951_at |
TBC1D2B |
TBC1 domain family, member 2B |
15 |
-76074381 |
AL137303 |
23102 |
15q24.3-q25.1 |
Hs.719242 |
2 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
212918_at |
RECQL |
RecQ protein-like (DNA helicase Q1-like) |
12 |
-21513111 |
AI962943 |
5965 |
12p12 |
Hs.235069 |
29 |
nucleotide binding DNA strand renaturation DNA strand annealing activity DNA binding ATP-dependent DNA helicase activity protein binding ATP binding nucleus DNA repair DNA recombination hydrolase activity |
|
1559500_at |
-0.888 |
5.971 |
-4.067 |
9.853e-04 |
0.223 |
-0.588 |
VPS8 |
vacuolar protein sorting 8 homolog (S. cerevisiae) |
3 |
186012624 |
BC036005 |
23355 |
3q27.2 |
Hs.269263 |
6 |
protein binding zinc ion binding metal ion binding |
|
243186_at |
FAM117B |
family with sequence similarity 117, member B |
2 |
203208145 |
AI523857 |
150864 |
2q33.2 |
Hs.471130 |
5 |
|
|
214545_s_at |
PROSC |
proline synthetase co-transcribed homolog (bacterial) |
8 |
37739258 |
NM_007198 |
11212 |
8p11.2 |
Hs.304792 Hs.608177 |
8 |
intracellular cytoplasm |
|
226704_at |
UBE2J2 |
ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast) |
1 |
-1179154 |
R76659 |
118424 |
1p36.33 |
Hs.191987 |
6 |
nucleotide binding ubiquitin-protein ligase activity ATP binding endoplasmic reticulum membrane integral to membrane ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis Parkinson's disease |
242442_x_at |
RG9MTD2 |
RNA (guanine-9-) methyltransferase domain containing 2 |
4 |
-100686894, -100686894 |
AL515269 |
93587 |
4q23 |
Hs.380412 |
1 |
methyltransferase activity transferase activity |
|
210448_s_at |
P2RX5 |
purinergic receptor P2X, ligand-gated ion channel, 5 |
17 |
-3540328, -3523270 |
U49396 |
5026 |
17p13.3 |
Hs.408615 |
15 |
purinergic nucleotide receptor activity transmembrane receptor activity ATP-gated cation channel activity ion channel activity ATP binding integral to plasma membrane ion transport signal transduction nervous system development positive regulation of calcium ion transport into cytosol membrane protein homodimerization activity protein heterodimerization activity positive regulation of calcium-mediated signaling |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
214696_at |
C17orf91 |
chromosome 17 open reading frame 91 |
17 |
-1561552, -1561552 |
AF070569 |
84981 |
17p13.3 |
Hs.597755 |
3 |
|
|
223716_s_at |
ZRANB2 |
zinc finger, RAN-binding domain containing 2 |
1 |
-71301561 |
AF065391 |
9406 |
1p31 |
Hs.194718 |
18 |
transcription factor activity RNA binding protein binding intracellular nucleus mRNA processing zinc ion binding RNA splicing metal ion binding |
|
214517_at |
KRTAP5-9 |
keratin associated protein 5-9 |
11 |
70937113 |
NM_005553 |
3846 |
11q13.5 |
Hs.709220 |
7 |
epidermis development keratin filament |
|
207693_at |
CACNB4 |
calcium channel, voltage-dependent, beta 4 subunit |
2 |
-152397533, -152397533, -152397533 |
NM_000726 |
785 |
2q22-q23 |
Hs.120725 |
25 |
voltage-gated ion channel activity voltage-gated calcium channel activity calcium ion binding protein binding cytosol voltage-gated calcium channel complex ion transport calcium ion transport internal side of plasma membrane regulation of calcium ion transport via voltage-gated calcium channel activity |
MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
239924_at |
LOC91316 |
glucuronidase, beta/ immunoglobulin lambda-like polypeptide 1 pseudogene |
22 |
-22310675 |
AA629699 |
91316 |
22q11.23 |
Hs.148656 |
4 |
|
|
229665_at |
0.429 |
6.178 |
2.807 |
1.313e-02 |
0.433 |
-2.787 |
CSTF3 |
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
11 |
-33119552, -33062705 |
AI653037 |
1479 |
11p13 |
Hs.44402 |
15 |
nuclear mRNA splicing, via spliceosome RNA binding protein binding intracellular nucleus mRNA polyadenylation mRNA cleavage |
|
218497_s_at |
RNASEH1 |
ribonuclease H1 |
2 |
-3570565 |
NM_002936 |
246243 |
2p25 |
Hs.568006 |
20 |
magnesium ion binding RNA binding endonuclease activity ribonuclease H activity ribonuclease activity cytoplasm mitochondrion RNA catabolic process hydrolase activity |
DNA replication |
201645_at |
1.857 |
4.142 |
2.593 |
2.021e-02 |
0.493 |
-3.151 |
TNC |
tenascin C |
9 |
-116822625 |
NM_002160 |
3371 |
9q33 |
Hs.143250 |
103 |
receptor binding extracellular region proteinaceous extracellular matrix cell adhesion signal transduction response to wounding |
Focal adhesion ECM-receptor interaction |
231863_at |
0.410 |
4.417 |
3.469 |
3.375e-03 |
0.308 |
-1.632 |
ING3 |
inhibitor of growth family, member 3 |
7 |
120378052, 120378052 |
AF161419 |
54556 |
7q31 |
Hs.489811 |
16 |
histone acetyltransferase activity protein binding nucleus zinc ion binding chromatin modification Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth positive regulation of apoptosis histone H4 acetylation histone H2A acetylation regulation of transcription metal ion binding |
|
216933_x_at |
APC |
adenomatous polyposis coli |
5 |
112071116, 112101454 |
S67788 |
324 |
5q21-q22 |
Hs.158932 |
386 |
cytokinesis after mitosis kinetochore kidney development hair follicle development nucleus cytoplasm centrosome cytosol cytoplasmic microtubule protein complex assembly response to DNA damage stimulus negative regulation of microtubule depolymerization cell cycle arrest mitotic metaphase/anaphase transition mitotic cell cycle spindle assembly checkpoint axonogenesis beta-catenin binding microtubule binding axis specification anterior/posterior pattern formation dorsal/ventral pattern formation proximal/distal pattern formation lateral plasma membrane protein kinase regulator activity protein kinase binding negative regulation of Wnt receptor signaling pathway positive regulation of cell migration growth cone positive regulation of epithelial cell differentiation beta-catenin destruction complex positive regulation of microtubule polymerization cell projection membrane positive regulation of pseudopodium assembly T cell differentiation in the thymus axon part Axin-APC-beta-catenin-GSK3B complex somatic stem cell maintenance negative regulation of odontogenesis cell projection positive regulation of apoptosis negative regulation of apoptosis negative regulation of MAPKKK cascade skin development regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process negative regulation of cyclin-dependent protein kinase activity positive regulation of cell adhesion muscle maintenance thymus development negative regulation of epithelial cell proliferation regulation of nitrogen compound metabolic process chromosome organization regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye Wnt receptor signaling pathway through beta-catenin Wnt receptor signaling pathway through beta-catenin |
Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma |
211362_s_at |
-0.336 |
3.393 |
-2.690 |
1.664e-02 |
0.465 |
-2.987 |
SERPINB13 |
serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
18 |
59405513 |
AF169949 |
5275 |
18q21.3-q22 |
Hs.241407 |
12 |
serine-type endopeptidase inhibitor activity cellular_component cytoplasm response to UV regulation of proteolysis peptidase inhibitor activity |
|
207642_at |
HCRT |
hypocretin (orexin) neuropeptide precursor |
17 |
-37589603 |
NM_001524 |
3060 |
17q21 |
Hs.158348 |
37 |
rough endoplasmic reticulum neuropeptide signaling pathway synaptic transmission feeding behavior synaptic vesicle cell junction cytoplasmic vesicle synapse perinuclear region of cytoplasm |
|
223441_at |
SLC17A5 |
solute carrier family 17 (anion/sugar transporter), member 5 |
6 |
-74359822 |
AK026921 |
26503 |
6q14-q15 |
Hs.597422 |
28 |
sugar:hydrogen symporter activity membrane fraction lysosomal membrane integral to plasma membrane transport anion transport symporter activity membrane |
Lysosome |
226810_at |
OGFRL1 |
opioid growth factor receptor-like 1 |
6 |
72055197 |
BE500942 |
79627 |
6q13 |
Hs.648434 Hs.656091 |
2 |
receptor activity membrane |
|
208096_s_at |
COL21A1 |
collagen, type XXI, alpha 1 |
6 |
-56029346 |
NM_030820 |
81578 |
6p12.3-p11.2 |
Hs.47629 |
7 |
structural molecule activity extracellular region proteinaceous extracellular matrix cytoplasm cell adhesion |
|
203075_at |
SMAD2 |
SMAD family member 2 |
18 |
-43613464, -43613463, -43613463 |
AW151617 |
4087 |
18q21.1 |
Hs.12253 Hs.705764 |
206 |
mesoderm formation double-stranded DNA binding transcription factor activity intracellular nucleus nucleoplasm cytoplasm cytosol SMAD protein complex assembly intracellular signaling cascade zygotic determination of dorsal/ventral axis gastrulation transcription factor binding anterior/posterior pattern formation positive regulation of epithelial to mesenchymal transition promoter binding transcription activator activity regulation of transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity primary microRNA processing ubiquitin protein ligase binding activin responsive factor complex type I transforming growth factor beta receptor binding positive regulation of gene-specific transcription cell fate commitment negative regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm morphogenesis regulation of binding palate development co-SMAD binding R-SMAD binding response to cholesterol |
Cell cycle Wnt signaling pathway TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer |
200896_x_at |
HDGF |
hepatoma-derived growth factor (high-mobility group protein 1-like) |
1 |
-154978522, -154978522, -154978522 |
NM_004494 |
3068 |
1q21-q23 |
Hs.506748 |
22 |
nucleotide binding DNA binding extracellular space nucleus cytoplasm signal transduction growth factor activity heparin binding cell proliferation regulation of transcription |
|
1554890_a_at |
TIA1 |
TIA1 cytotoxic granule-associated RNA binding protein |
2 |
-70290079 |
BC015944 |
7072 |
2p13 |
Hs.413123 |
34 |
nucleotide binding RNA binding protein binding apoptosis induction of apoptosis poly(A) RNA binding |
|
228132_at |
ABLIM2 |
actin binding LIM protein family, member 2 |
4 |
-8059647, -8017936 |
AI240129 |
84448 |
4p16.1 |
Hs.233404 |
9 |
actin binding cytoplasm cytoskeleton organization zinc ion binding actin cytoskeleton myofibril positive regulation of transcription from RNA polymerase II promoter metal ion binding |
Axon guidance |
219681_s_at |
RAB11FIP1 |
RAB11 family interacting protein 1 (class I) |
8 |
-37837342, -37837342, -37835627 |
NM_025151 |
80223 |
8p11.22 |
Hs.696035 |
19 |
protein binding protein transport membrane phagocytic vesicle membrane cytoplasmic vesicle recycling endosome |
Endocytosis |
202619_s_at |
PLOD2 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
3 |
-147269917 |
AI754404 |
5352 |
3q23-q24 |
Hs.477866 |
20 |
response to hypoxia iron ion binding protein binding endoplasmic reticulum protein modification process procollagen-lysine 5-dioxygenase activity membrane oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction |
Lysine degradation |
1563466_at |
MYLK |
myosin light chain kinase |
3 |
-124813832, -124813832 |
AL832211 |
4638 |
3q21 |
Hs.477375 |
56 |
nucleotide binding magnesium ion binding actin binding myosin light chain kinase activity calcium ion binding calmodulin binding ATP binding protein amino acid phosphorylation transferase activity |
Calcium signaling pathway Vascular smooth muscle contraction Focal adhesion Regulation of actin cytoskeleton |
212392_s_at |
0.991 |
6.396 |
2.923 |
1.038e-02 |
0.418 |
-2.588 |
PDE4DIP |
phosphodiesterase 4D interacting protein |
1 |
-143663117, -143663117, -143601947, -143601947, -143562783 |
AI950145 |
9659 |
1q12 |
Hs.584841 Hs.613082 Hs.657186 Hs.657490 Hs.719077 |
10 |
nucleus cytoplasm Golgi apparatus centrosome |
|
1557910_at |
0.634 |
8.999 |
3.054 |
7.928e-03 |
0.384 |
-2.359 |
HSP90AB1 |
heat shock protein 90kDa alpha (cytosolic), class B member 1 |
6 |
44322826 |
BG612458 |
3326 |
6p12 |
Hs.509736 Hs.689683 Hs.701787 |
50 |
nucleotide binding ATP binding cytoplasm protein folding response to unfolded protein nitric-oxide synthase regulator activity TPR domain binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process melanosome positive regulation of nitric oxide biosynthetic process unfolded protein binding regulation of interferon-gamma-mediated signaling pathway regulation of type I interferon-mediated signaling pathway |
Antigen processing and presentation Pathways in cancer Prostate cancer |
200075_s_at |
0.416 |
7.980 |
2.566 |
2.133e-02 |
0.497 |
-3.196 |
GUK1 |
guanylate kinase 1 |
1 |
226394551, 226399026 |
BC006249 |
2987 |
1q32-q41 |
Hs.376933 |
11 |
nucleotide binding guanylate kinase activity ATP binding cytosol purine nucleotide metabolic process kinase activity transferase activity nucleoside kinase activity |
Purine metabolism Metabolic pathways |
1564627_at |
DNAJC13 |
DnaJ (Hsp40) homolog, subfamily C, member 13 |
3 |
133619242 |
AK098729 |
23317 |
3q22.1 |
Hs.12707 |
10 |
binding heat shock protein binding |
|
231953_at |
BPTF |
bromodomain PHD finger transcription factor |
17 |
63252241 |
AK027184 |
2186 |
17q24.3 |
Hs.444200 |
22 |
negative regulation of transcription from RNA polymerase II promoter nucleus cytoplasm chromatin remodeling brain development DNA-dependent ATPase activity transcription factor binding zinc ion binding transcription regulator activity positive regulation of gene-specific transcription sequence-specific DNA binding sequence-specific DNA binding regulation of transcription metal ion binding |
|
212864_at |
0.359 |
5.190 |
2.614 |
1.938e-02 |
0.489 |
-3.115 |
CDS2 |
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
20 |
5055481 |
Y16521 |
8760 |
20p13 |
Hs.719252 |
9 |
phosphatidate cytidylyltransferase activity mitochondrion mitochondrial inner membrane phospholipid biosynthetic process membrane integral to membrane nucleotidyltransferase activity |
Glycerophospholipid metabolism Metabolic pathways Phosphatidylinositol signaling system |
234580_at |
-0.259 |
5.999 |
-2.143 |
4.869e-02 |
0.590 |
-3.882 |
TMEM106A |
transmembrane protein 106A |
17 |
38719419, 481039 |
U25750 |
113277 |
17q21.31 |
Hs.567647 |
3 |
molecular_function cellular_component biological_process membrane integral to membrane |
|
206647_at |
-0.229 |
4.149 |
-2.367 |
3.161e-02 |
0.544 |
-3.525 |
HBZ |
hemoglobin, zeta |
16 |
142853 |
NM_005332 |
3050 |
16p13.3 |
Hs.585357 |
24 |
oxygen transporter activity hemoglobin complex transport oxygen transport oxygen binding heme binding metal ion binding |
|
232720_at |
LINGO2 |
leucine rich repeat and Ig domain containing 2 |
9 |
-27938527 |
AL353746 |
158038 |
9p21.2-p21.1 |
Hs.715650 |
4 |
protein binding membrane integral to membrane |
|
238648_at |
FLJ42291 |
hypothetical LOC346547 |
7 |
|
BE671597 |
346547 |
7q36.2 |
|
|
|
|
223645_s_at |
CYorf15B |
chromosome Y open reading frame 15B |
Y |
20217829 |
BF062193 |
84663 |
Yq11.222 |
Hs.592254 |
4 |
|
|
201171_at |
0.295 |
3.558 |
2.672 |
1.726e-02 |
0.471 |
-3.018 |
ATP6V0E1 |
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
5 |
172343368 |
NM_003945 |
8992 |
5q35.1 |
Hs.484188 |
18 |
transporter activity membrane fraction ion transport vacuolar acidification ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport membrane integral to membrane cell growth hydrolase activity proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions proton-transporting ATPase activity, rotational mechanism |
Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection |
222847_s_at |
0.335 |
5.277 |
2.385 |
3.051e-02 |
0.541 |
-3.496 |
EGLN3 |
egl nine homolog 3 (C. elegans) |
14 |
-33463171 |
AI378406 |
112399 |
14q13.1 |
Hs.135507 |
26 |
iron ion binding protein binding nucleus cytoplasm apoptosis oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen L-ascorbic acid binding metal ion binding oxidation reduction |
Pathways in cancer Renal cell carcinoma |
225500_x_at |
SCAF1 |
SR-related CTD-associated factor 1 |
19 |
54837193 |
AF254411 |
58506 |
19q13.3-q13.4 |
Hs.103521 |
6 |
RNA binding nucleus mRNA processing RNA splicing |
|
218164_at |
0.527 |
7.072 |
3.338 |
4.419e-03 |
0.330 |
-1.862 |
SPATA20 |
spermatogenesis associated 20 |
17 |
45979560 |
NM_022827 |
64847 |
17q21.33 |
Hs.103147 |
7 |
catalytic activity protein binding multicellular organismal development spermatogenesis cell differentiation |
|
223994_s_at |
SLC12A9 |
solute carrier family 12 (potassium/chloride transporters), member 9 |
7 |
100288293 |
BC000154 |
56996 |
7q22 |
Hs.521087 |
6 |
plasma membrane transport integral to membrane |
|
203762_s_at |
0.341 |
4.976 |
2.182 |
4.515e-02 |
0.581 |
-3.820 |
DYNC2LI1 |
dynein, cytoplasmic 2, light intermediate chain 1 |
2 |
43854685, 43854685, 43854685 |
NM_016008 |
51626 |
2p25.1-p24.1 |
Hs.371597 |
7 |
motor activity cytoplasm microtubule cilium multicellular organismal development determination of left/right symmetry cell projection organization dynein complex cilium axoneme cilium assembly |
|
212888_at |
DICER1 |
dicer 1, ribonuclease type III |
14 |
-94622317, -94622317 |
BG109746 |
23405 |
14q32.13 |
Hs.87889 |
63 |
nucleotide binding magnesium ion binding angiogenesis double-stranded RNA binding helicase activity endonuclease activity ribonuclease III activity protein binding ATP binding intracellular cytoplasm RNA processing ATP-dependent helicase activity RNA-induced silencing complex hydrolase activity stem cell maintenance manganese ion binding lung development RNA interference, production of siRNA RNA interference, targeting of mRNA for destruction gene silencing by RNA pre-microRNA processing embryonic hindlimb morphogenesis branching morphogenesis of a tube |
|
221479_s_at |
0.455 |
7.930 |
2.512 |
2.376e-02 |
0.509 |
-3.287 |
BNIP3L |
BCL2/adenovirus E1B 19kDa interacting protein 3-like |
8 |
26296439 |
AF060922 |
665 |
8p21 |
Hs.131226 |
19 |
lamin binding lamin binding nucleus nuclear envelope mitochondrion mitochondrial envelope endoplasmic reticulum induction of apoptosis negative regulation of survival gene product expression membrane integral to membrane protein homodimerization activity negative regulation of apoptosis interspecies interaction between organisms protein heterodimerization activity defense response to virus |
|
1559927_a_at |
LOC728353 |
hypothetical protein LOC728353 |
14 |
|
BC031683 |
728353 |
14q11.2 |
Hs.621210 |
|
|
|
209486_at |
UTP3 |
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
4 |
71773059 |
BC004546 |
57050 |
4q13.3 |
Hs.322901 |
15 |
molecular_function protein binding nucleus nucleolus multicellular organismal development brain development gene silencing chromatin modification |
|
215688_at |
-0.362 |
4.718 |
-3.265 |
5.140e-03 |
0.347 |
-1.990 |
RASGRF1 |
Ras protein-specific guanine nucleotide-releasing factor 1 |
15 |
-77039345, -77039345 |
AL359931 |
5923 |
15q24.2 |
Hs.459035 |
24 |
Rho guanyl-nucleotide exchange factor activity protein binding intracellular cytosol plasma membrane long-term memory synaptosome growth cone neuron projection development positive regulation of Ras GTPase activity activation of Rac GTPase activity regulation of Rac protein signal transduction regulation of Rho protein signal transduction |
MAPK signaling pathway Focal adhesion |
212464_s_at |
1.084 |
8.243 |
3.607 |
2.537e-03 |
0.287 |
-1.389 |
FN1 |
fibronectin 1 |
2 |
-215987628, -215933423 |
X02761 |
2335 |
2q34 |
Hs.203717 |
291 |
extracellular matrix structural constituent collagen binding extracellular region extracellular region fibrinogen complex proteinaceous extracellular matrix ER-Golgi intermediate compartment acute-phase response cell adhesion heparin binding regulation of cell shape response to wounding cell migration peptide cross-linking platelet alpha granule lumen substrate adhesion-dependent cell spreading |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer |
243358_at |
IGF1R |
insulin-like growth factor 1 receptor |
15 |
97010283 |
BF347362 |
3480 |
15q26.3 |
Hs.643120 Hs.653608 Hs.714012 |
315 |
nucleotide binding receptor activity insulin-like growth factor receptor activity insulin receptor binding ATP binding microsome integral to plasma membrane anti-apoptosis immune response signal transduction brain development positive regulation of cell proliferation insulin receptor signaling pathway organ morphogenesis phosphoinositide 3-kinase cascade membrane transferase activity male sex determination positive regulation of cell migration mammary gland development insulin-like growth factor I binding identical protein binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of DNA replication protein amino acid autophosphorylation insulin-like growth factor receptor signaling pathway phosphoinositide-mediated signaling protein tetramerization |
Endocytosis Focal adhesion Adherens junction Long-term depression Pathways in cancer Colorectal cancer Glioma Prostate cancer Melanoma |
1554287_at |
TRIM4 |
tripartite motif-containing 4 |
7 |
-99325971 |
BC011763 |
89122 |
7q22-q31.1 |
Hs.50749 |
8 |
protein binding intracellular cytoplasm zinc ion binding metal ion binding protein trimerization |
|
1552395_at |
-0.327 |
6.430 |
-2.823 |
1.272e-02 |
0.431 |
-2.760 |
TSSK3 |
testis-specific serine kinase 3 |
1 |
32600448 |
NM_052841 |
81629 |
1p35-p34 |
Hs.512763 |
5 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation multicellular organismal development spermatogenesis transferase activity cell differentiation |
|
1562841_at |
LOC339666 |
hypothetical protein LOC339666 |
22 |
|
BC041349 |
339666 |
22q12.3 |
Hs.654761 |
1 |
|
|
214710_s_at |
CCNB1 |
cyclin B1 |
5 |
68498668 |
BE407516 |
891 |
5q12 |
Hs.23960 |
155 |
G2/M transition of mitotic cell cycle protein binding cellular_component nucleus nucleoplasm cytoplasm centrosome cytosol cell cycle mitosis anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle p53 signaling pathway |
1564423_a_at |
-0.307 |
3.487 |
-2.927 |
1.029e-02 |
0.418 |
-2.580 |
SEC16B |
SEC16 homolog B (S. cerevisiae) |
1 |
-176164864 |
AK098627 |
89866 |
1q25.2 |
Hs.709633 |
10 |
endoplasmic reticulum Golgi apparatus protein transport membrane vesicle-mediated transport |
|
238338_at |
DCAF8 |
DDB1 and CUL4 associated factor 8 |
1 |
-158475636, -158475636, -158452128, -158452128 |
AL134577 |
50717 |
1q22-q23 |
Hs.632447 |
10 |
protein binding |
|
229793_at |
0.667 |
5.317 |
3.791 |
1.736e-03 |
0.267 |
-1.067 |
ASAH2B |
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B |
10 |
52169713 |
AI656964 |
653308 |
10q11.23 |
Hs.710005 |
2 |
|
|
1558177_at |
C14orf83 |
chromosome 14 open reading frame 83 |
14 |
-67006735 |
AK090706 |
161145 |
14q24.1 |
Hs.509707 |
3 |
membrane integral to membrane |
|
208623_s_at |
1.196 |
6.073 |
3.387 |
3.994e-03 |
0.323 |
-1.775 |
EZR |
ezrin |
6 |
-159106760, -159106760 |
J05021 |
7430 |
6q25.2-q26 |
Hs.487027 |
158 |
ruffle cytoplasm cytosol actin filament plasma membrane microvillus cell cortex cytoskeletal anchoring at plasma membrane leukocyte adhesion cytoskeletal protein binding regulation of cell shape extrinsic to membrane membrane to membrane docking filopodium cortical cytoskeleton apical part of cell cell adhesion molecule binding actin filament binding actin filament bundle formation |
Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC |
209218_at |
SQLE |
squalene epoxidase |
8 |
126079900 |
AF098865 |
6713 |
8q24.1 |
Hs.71465 |
16 |
squalene monooxygenase activity squalene monooxygenase activity endoplasmic reticulum endoplasmic reticulum membrane microsome membrane integral to membrane sterol biosynthetic process oxidoreductase activity FAD binding oxidation reduction |
Steroid biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
211537_x_at |
0.421 |
5.912 |
2.632 |
1.870e-02 |
0.487 |
-3.086 |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
6 |
-91282073, -91282073 |
AF218074 |
6885 |
6q16.1-q16.3 |
Hs.719192 |
114 |
nucleotide binding magnesium ion binding positive regulation of T cell cytokine production protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction transforming growth factor beta receptor signaling pathway activation of NF-kappaB-inducing kinase activity transferase activity positive regulation of interleukin-2 production T cell receptor signaling pathway positive regulation of T cell activation |
MAPK signaling pathway Wnt signaling pathway Adherens junction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway T cell receptor signaling pathway |
205527_s_at |
GEMIN4 |
gem (nuclear organelle) associated protein 4 |
17 |
-594410 |
NM_015487 |
50628 |
17p13 |
Hs.499620 |
24 |
spliceosomal snRNP biogenesis protein binding nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm cytosol rRNA processing mRNA processing RNA splicing Cajal body small nuclear ribonucleoprotein complex |
|
210664_s_at |
0.730 |
5.434 |
3.684 |
2.167e-03 |
0.276 |
-1.255 |
TFPI |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
2 |
-188051550, -188037202 |
AF021834 |
7035 |
2q32 |
Hs.516578 |
118 |
serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway |
Complement and coagulation cascades |
242408_at |
0.328 |
3.130 |
2.597 |
2.007e-02 |
0.491 |
-3.145 |
STYX |
serine/threonine/tyrosine interacting protein |
14 |
52266632 |
AW968935 |
6815 |
|
Hs.364980 |
8 |
protein amino acid dephosphorylation protein tyrosine/serine/threonine phosphatase activity hydrolase activity |
|
205357_s_at |
AGTR1 |
angiotensin II receptor, type 1 |
3 |
149898347, 149930656 |
NM_000685 |
185 |
3q21-q25 |
Hs.477887 Hs.719071 |
524 |
regulation of cell growth angiotensin type I receptor activity angiotensin type I receptor activity kidney development renin-angiotensin regulation of aldosterone production regulation of blood vessel size by renin-angiotensin regulation of natriuresis receptor activity G-protein coupled receptor activity angiotensin type II receptor activity plasma membrane integral to plasma membrane oxygen and reactive oxygen species metabolic process signal transduction acetyltransferase activator activity positive regulation of foam cell differentiation positive regulation of cholesterol esterification regulation of vasoconstriction regulation of vasoconstriction regulation of vasoconstriction calcium-mediated signaling bradykinin receptor binding positive regulation of cellular protein metabolic process positive regulation of phospholipase A2 activity positive regulation of NAD(P)H oxidase activity low-density lipoprotein particle remodeling regulation of cell proliferation regulation of vasodilation protein heterodimerization activity positive regulation of inflammatory response elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
Calcium signaling pathway Neuroactive ligand-receptor interaction Vascular smooth muscle contraction Renin-angiotensin system |
1556988_s_at |
CHD1L |
chromodomain helicase DNA binding protein 1-like |
1 |
145180914 |
BE220618 |
9557 |
1q12 |
Hs.191164 |
12 |
nucleotide binding DNA binding helicase activity ATP binding nucleus ATP-dependent helicase activity hydrolase activity |
|
224938_at |
NUFIP2 |
nuclear fragile X mental retardation protein interacting protein 2 |
17 |
-24606979 |
AW007746 |
57532 |
17q11.2 |
Hs.462598 |
13 |
RNA binding protein binding nucleus cytoplasm Golgi apparatus polysomal ribosome |
|
225182_at |
TMEM50B |
transmembrane protein 50B |
21 |
-33743317 |
AL355685 |
757 |
21q22.11 |
Hs.433668 |
8 |
molecular_function endoplasmic reticulum plasma membrane biological_process integral to membrane |
|
1563781_at |
LOC285949 |
hypothetical protein LOC285949 |
7 |
|
AK096687 |
285949 |
7p15.1 |
Hs.561708 |
1 |
|
|
229389_at |
-0.410 |
5.089 |
-3.485 |
3.263e-03 |
0.307 |
-1.603 |
ATG16L2 |
ATG16 autophagy related 16-like 2 (S. cerevisiae) |
11 |
72203098 |
AA741058 |
89849 |
11q13.4 |
Hs.653186 |
3 |
cytoplasm autophagy protein transport |
|
1559083_x_at |
LOC284600 |
hypothetical protein LOC284600 |
1 |
|
AK056486 |
284600 |
1p36.33 |
Hs.551839 |
2 |
|
|
229983_at |
TIGD2 |
tigger transposable element derived 2 |
4 |
90252990 |
AI610112 |
166815 |
4q22.1 |
Hs.58924 |
5 |
chromosome, centromeric region DNA binding nucleus regulation of transcription |
|
220745_at |
IL19 |
interleukin 19 |
1 |
205038837, 205068844 |
NM_013371 |
29949 |
1q32.2 |
Hs.661017 |
35 |
cytokine activity extracellular region extracellular space oxygen and reactive oxygen species metabolic process apoptosis induction of apoptosis immune response signal transduction interleukin-6 biosynthetic process |
Cytokine-cytokine receptor interaction Jak-STAT signaling pathway |
211057_at |
ROR1 |
receptor tyrosine kinase-like orphan receptor 1 |
1 |
64012277, 64012277 |
BC006374 |
4919 |
1p32-p31 |
Hs.654491 |
13 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding cytoplasm plasma membrane integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway transferase activity |
|
210201_x_at |
BIN1 |
bridging integrator 1 |
2 |
-127522077, -127522076 |
AF001383 |
274 |
2q14 |
Hs.193163 |
69 |
protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms |
|
238662_at |
ATPBD4 |
ATP binding domain 4 |
15 |
-33599765, -33450461 |
BE884544 |
89978 |
15q14 |
Hs.107196 |
4 |
|
|
221355_at |
0.476 |
5.177 |
3.641 |
2.365e-03 |
0.284 |
-1.330 |
CHRNG |
cholinergic receptor, nicotinic, gamma |
2 |
233112680 |
NM_005199 |
1146 |
2q33-q34 |
Hs.248101 |
17 |
nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity plasma membrane integral to plasma membrane ion transport muscle contraction signal transduction channel activity acetylcholine receptor activity cell junction synapse postsynaptic membrane |
|
203194_s_at |
NUP98 |
nucleoporin 98kDa |
11 |
-3689634, -3652815 |
AA527238 |
4928 |
11p15.5 |
Hs.524750 |
78 |
protein import into nucleus, docking kinetochore transporter activity protein binding nucleus nucleoplasm DNA replication nucleocytoplasmic transport nuclear pore organization protein transport membrane structural constituent of nuclear pore Nup107-160 complex Nup107-160 complex interspecies interaction between organisms mRNA transport intracellular protein transmembrane transport |
|
235504_at |
0.438 |
4.434 |
2.190 |
4.454e-02 |
0.580 |
-3.809 |
GREM2 |
gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) |
1 |
-238719495 |
BE786990 |
64388 |
1q43 |
Hs.98206 |
9 |
cytokine activity extracellular region extracellular region extracellular space BMP signaling pathway |
|
225665_at |
ZAK |
sterile alpha motif and leucine zipper containing kinase AZK |
2 |
173648810, 173648810 |
AI129320 |
51776 |
2q24.2 |
Hs.444451 |
24 |
cell cycle checkpoint DNA damage checkpoint nucleotide binding activation of MAPKK activity magnesium ion binding protein serine/threonine kinase activity MAP kinase kinase kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm response to stress cell cycle cell cycle arrest protein kinase cascade activation of JUN kinase activity cell death cell proliferation response to radiation transferase activity cell differentiation identical protein binding positive regulation of apoptosis |
MAPK signaling pathway Tight junction |
201082_s_at |
DCTN1 |
dynactin 1 (p150, glued homolog, Drosophila) |
2 |
-74441789, -74441789 |
NM_004082 |
1639 |
2p13 |
Hs.516111 |
74 |
spindle pole motor activity protein binding cytoplasm cytoskeleton microtubule mitosis nervous system development cell death dynein complex |
Huntington's disease |
221778_at |
JHDM1D |
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) |
7 |
-139431014 |
BE217882 |
80853 |
7q34 |
Hs.308710 |
3 |
protein binding zinc ion binding metal ion binding |
|
215415_s_at |
LYST |
lysosomal trafficking regulator |
1 |
-233890968 |
U70064 |
1130 |
1q42.1-q42.2 |
Hs.532411 |
23 |
protein binding cytoplasm protein transport microtubule cytoskeleton leukocyte chemotaxis melanosome organization endosome to lysosome transport via multivesicular body sorting pathway mast cell secretory granule organization natural killer cell mediated cytotoxicity defense response to bacterium defense response to protozoan pigmentation defense response to virus |
|
202257_s_at |
CD2BP2 |
CD2 (cytoplasmic tail) binding protein 2 |
16 |
-30269588, -30269588 |
NM_006110 |
10421 |
16p11.2 |
Hs.202677 |
21 |
nuclear mRNA splicing, via spliceosome protein binding cytoplasm |
|
201214_s_at |
PPP1R7 |
protein phosphatase 1, regulatory (inhibitor) subunit 7 |
2 |
241738574 |
NM_002712 |
5510 |
2q37.3 |
Hs.36587 |
10 |
protein binding nucleus cytoplasm biological_process protein phosphatase type 1 regulator activity enzyme regulator activity |
|
228239_at |
FAM165B |
family with sequence similarity 165, member B |
21 |
34669618 |
AA148789 |
54065 |
21q22.12 |
Hs.656195 |
7 |
molecular_function cellular_component biological_process membrane integral to membrane |
|
223281_s_at |
COX15 |
COX15 homolog, cytochrome c oxidase assembly protein (yeast) |
10 |
-101458494 |
AF026850 |
1355 |
10q24 |
Hs.28326 |
9 |
catalytic activity cytochrome-c oxidase activity mitochondrial respiratory chain mitochondrial electron transport, cytochrome c to oxygen protein complex assembly heme a biosynthetic process respiratory gaseous exchange respiratory chain complex IV assembly membrane integral to membrane mitochondrial part cellular respiration oxidation reduction |
Oxidative phosphorylation Porphyrin and chlorophyll metabolism Metabolic pathways |
39313_at |
WNK1 |
WNK lysine deficient protein kinase 1 |
12 |
732485 |
AB002342 |
65125 |
12p13.3 |
Hs.709894 |
51 |
nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process |
|
204622_x_at |
NR4A2 |
nuclear receptor subfamily 4, group A, member 2 |
2 |
-156889189 |
NM_006186 |
4929 |
2q22-q23 |
Hs.563344 |
76 |
transcription factor activity steroid hormone receptor activity nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding cellular response to extracellular stimulus sequence-specific DNA binding metal ion binding response to protein stimulus |
|
224078_at |
-0.221 |
6.931 |
-2.337 |
3.349e-02 |
0.552 |
-3.573 |
HIATL2 |
hippocampus abundant transcript-like 2 |
9 |
-98748147 |
BC005058 |
84278 |
9q22.33 |
Hs.610084 |
3 |
transporter activity transport membrane integral to membrane |
|
229044_at |
NUDT17 |
nudix (nucleoside diphosphate linked moiety X)-type motif 17 |
1 |
-144297851 |
AA284522 |
200035 |
1q21.1 |
Hs.585066 |
4 |
magnesium ion binding mitochondrion hydrolase activity manganese ion binding |
|
201213_at |
PPP1R7 |
protein phosphatase 1, regulatory (inhibitor) subunit 7 |
2 |
241738574 |
AI090331 |
5510 |
2q37.3 |
Hs.36587 |
10 |
protein binding nucleus cytoplasm biological_process protein phosphatase type 1 regulator activity enzyme regulator activity |
|
217858_s_at |
ARMCX3 |
armadillo repeat containing, X-linked 3 |
X |
100764775, 100765006 |
NM_016607 |
51566 |
Xq21.33-q22.2 |
Hs.592225 |
13 |
binding membrane integral to membrane |
|
39549_at |
NPAS2 |
neuronal PAS domain protein 2 |
2 |
100803044 |
AI743090 |
4862 |
2q11.2 |
Hs.156832 Hs.705895 |
23 |
transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding |
Circadian rhythm - mammal |
234291_s_at |
SLC6A20 |
solute carrier family 6 (proline IMINO transporter), member 20 |
3 |
-45771944 |
AL389979 |
54716 |
3p21.3 |
Hs.413095 |
5 |
neurotransmitter:sodium symporter activity plasma membrane integral to plasma membrane neurotransmitter transport amino acid transport amino acid transmembrane transporter activity symporter activity apical plasma membrane |
|
225351_at |
0.435 |
7.218 |
2.562 |
2.148e-02 |
0.497 |
-3.202 |
FAM45A |
family with sequence similarity 45, member A |
10 |
120853600 |
AI697488 |
404636 |
10q25 |
Hs.434241 |
3 |
|
|
220712_at |
C8orf60 |
chromosome 8 open reading frame 60 |
8 |
|
NM_024984 |
619426 |
8q24.3 |
|
1 |
|
|
238253_at |
WDR72 |
WD repeat domain 72 |
15 |
-51593229 |
AI733060 |
256764 |
15q21.3 |
Hs.122125 |
4 |
|
|
217883_at |
MMADHC |
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria |
2 |
-150134395 |
NM_015702 |
27249 |
2q23.2 |
Hs.5324 |
7 |
mitochondrion |
|
238051_x_at |
PWWP2B |
PWWP domain containing 2B |
10 |
134060691 |
AI918314 |
170394 |
10q26.3 |
Hs.527751 |
5 |
|
|
205687_at |
UBFD1 |
ubiquitin family domain containing 1 |
16 |
23476362 |
NM_019116 |
56061 |
16p12 |
Hs.3459 |
3 |
|
|
210707_x_at |
PMS2L11 |
postmeiotic segregation increased 2-like 11 pseudogene |
7 |
76448074 |
U38980 |
441263 |
7q11.23 |
Hs.675888 |
5 |
|
|
221676_s_at |
0.514 |
5.968 |
3.475 |
3.335e-03 |
0.308 |
-1.622 |
CORO1C |
coronin, actin binding protein, 1C |
12 |
-107563015 |
BC002342 |
23603 |
12q24.1 |
Hs.330384 |
12 |
actin binding phagocytosis signal transduction actin cytoskeleton |
|
238054_at |
ADPRHL1 |
ADP-ribosylhydrolase like 1 |
13 |
-113124584, -113124260 |
AI243209 |
113622 |
13q34 |
Hs.98669 |
4 |
magnesium ion binding ADP-ribosylarginine hydrolase activity hydrolase activity protein amino acid de-ADP-ribosylation |
|
228063_s_at |
0.465 |
5.957 |
2.187 |
4.480e-02 |
0.581 |
-3.814 |
NAP1L5 |
nucleosome assembly protein 1-like 5 |
4 |
-89836096 |
AW025330 |
266812 |
4q21-q22 4q22.1 |
Hs.12554 |
8 |
protein binding nucleus nucleosome assembly |
|
214668_at |
C13orf1 |
chromosome 13 open reading frame 1 |
13 |
-49384842 |
BG532405 |
57213 |
13q14 |
Hs.44235 |
11 |
|
|
233947_s_at |
LOC255480 |
hypothetical protein LOC255480 |
12 |
|
U47671 |
255480 |
12q24.21 |
Hs.567915 |
1 |
|
|
219618_at |
IRAK4 |
interleukin-1 receptor-associated kinase 4 |
12 |
42439013 |
NM_016123 |
51135 |
12q12 |
Hs.138499 |
49 |
nucleotide binding magnesium ion binding cytokine production protein serine/threonine kinase activity interleukin-1 receptor binding protein binding ATP binding cytosol protein amino acid phosphorylation signal transduction I-kappaB kinase/NF-kappaB cascade transferase activity cytokine-mediated signaling pathway |
Apoptosis Toll-like receptor signaling pathway Neurotrophin signaling pathway |
228633_s_at |
CNTROB |
centrobin, centrosomal BRCA2 interacting protein |
17 |
7776197 |
AI668799 |
116840 |
17p13.1 |
Hs.348012 |
8 |
cytokinesis centriole cell cycle centriole replication protein domain specific binding centrosome separation |
|
207685_at |
CRYBB3 |
crystallin, beta B3 |
22 |
23925824 |
NM_004076 |
1417 |
22q11.2-q12.1 22q11.23 |
Hs.533022 |
12 |
structural constituent of eye lens protein binding visual perception |
|
1554705_at |
SCARA5 |
scavenger receptor class A, member 5 (putative) |
8 |
-27783668 |
BC033153 |
286133 |
8p21.1 |
Hs.591833 |
6 |
receptor activity scavenger receptor activity iron ion binding protein binding plasma membrane integral to plasma membrane ion transport cellular iron ion homeostasis endocytosis cell surface cellular response to heat iron ion transmembrane transport protein homotrimerization ferritin receptor activity |
|
225702_at |
C8orf76 |
chromosome 8 open reading frame 76 |
8 |
-124301411 |
AA973041 |
84933 |
8q24.13 |
Hs.521800 |
4 |
binding |
|
203099_s_at |
CDYL |
chromodomain protein, Y-like |
6 |
4651391, 4721678, 4781330, 4835224 |
AF081258 |
9425 |
6p25.1 |
Hs.269092 |
8 |
chromatin chromatin binding histone acetyltransferase activity nucleus chromatin assembly or disassembly spermatogenesis metabolic process acyltransferase activity transferase activity regulation of transcription |
|
219002_at |
FASTKD1 |
FAST kinase domains 1 |
2 |
-170094508 |
NM_024622 |
79675 |
2q31 |
Hs.529276 |
6 |
protein kinase activity ATP binding apoptosis |
|
204478_s_at |
RABIF |
RAB interacting factor |
1 |
-201114708 |
NM_002871 |
5877 |
1q32-q41 |
Hs.90875 |
13 |
guanyl-nucleotide exchange factor activity membrane fusion small GTPase mediated signal transduction zinc ion binding protein transport metal ion binding |
|
224699_s_at |
ESYT2 |
extended synaptotagmin-like protein 2 |
7 |
-158216449 |
BE385892 |
57488 |
7q36.3 |
Hs.490795 |
10 |
plasma membrane integral to membrane |
|
224595_at |
SLC44A1 |
solute carrier family 44, member 1 |
9 |
107046749 |
AK022549 |
23446 |
9q31.2 |
Hs.573495 |
14 |
transport choline transmembrane transporter activity choline transport membrane integral to membrane |
|
239443_at |
PCDHB6 |
protocadherin beta 6 |
5 |
140510022 |
AI821557 |
56130 |
5q31 |
Hs.283085 |
7 |
calcium ion binding protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion synaptic transmission synaptogenesis calcium-dependent cell-cell adhesion |
|
220488_s_at |
BCAS3 |
breast carcinoma amplified sequence 3 |
17 |
56109953 |
NM_017679 |
54828 |
17q23 |
Hs.655028 |
12 |
nucleus |
|
230430_at |
ENTPD2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
9 |
-139062373 |
AW134837 |
954 |
9q34 |
Hs.123036 |
14 |
magnesium ion binding calcium ion binding membrane integral to membrane hydrolase activity |
Purine metabolism |
227810_at |
ZNF558 |
zinc finger protein 558 |
19 |
-8781381 |
AW119060 |
148156 |
19p13.2 |
Hs.659797 |
4 |
DNA binding protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
222692_s_at |
0.455 |
5.378 |
2.717 |
1.577e-02 |
0.459 |
-2.942 |
FNDC3B |
fibronectin type III domain containing 3B |
3 |
173240111, 173241037 |
BF444916 |
64778 |
3q26.31 |
Hs.159430 |
9 |
endoplasmic reticulum membrane integral to membrane |
|
1553039_a_at |
-0.239 |
7.101 |
-2.714 |
1.585e-02 |
0.459 |
-2.946 |
ASB10 |
ankyrin repeat and SOCS box-containing 10 |
7 |
-150503717, -150503717 |
NM_080871 |
136371 |
7q36.1 |
Hs.647081 |
6 |
intracellular signaling cascade modification-dependent protein catabolic process |
|
224431_s_at |
SUV420H2 |
suppressor of variegation 4-20 homolog 2 (Drosophila) |
19 |
60543032 |
BC005842 |
84787 |
19q13.42 |
Hs.590982 |
6 |
protein binding nucleus chromosome methyltransferase activity chromatin modification transferase activity histone-lysine N-methyltransferase activity regulation of transcription |
Lysine degradation |
239890_s_at |
SERP2 |
stress-associated endoplasmic reticulum protein family member 2 |
13 |
43845977 |
BG054503 |
387923 |
13q14.11 |
Hs.377972 |
4 |
endoplasmic reticulum protein transport membrane integral to membrane intracellular protein transmembrane transport |
|
225798_at |
JAZF1 |
JAZF zinc finger 1 |
7 |
-27836717 |
AL047908 |
221895 |
7p15.2-p15.1 |
Hs.368944 |
39 |
negative regulation of transcription from RNA polymerase II promoter nucleic acid binding transcription corepressor activity intracellular nucleus zinc ion binding transcriptional repressor complex regulation of transcription metal ion binding |
|
206907_at |
TNFSF9 |
tumor necrosis factor (ligand) superfamily, member 9 |
19 |
6482009 |
NM_003811 |
8744 |
19p13.3 |
Hs.1524 |
32 |
cytokine activity tumor necrosis factor receptor binding extracellular space apoptosis immune response signal transduction cell-cell signaling cell proliferation membrane integral to membrane |
Cytokine-cytokine receptor interaction |
215245_x_at |
0.393 |
6.486 |
2.324 |
3.437e-02 |
0.553 |
-3.595 |
FMR1 |
fragile X mental retardation 1 |
X |
146801200 |
AA830884 |
2332 |
Xq27.3 |
Hs.103183 |
211 |
mRNA binding protein binding soluble fraction nucleus nucleoplasm nucleolus cytoplasm transport polysomal ribosome mRNA transport |
|
214884_at |
-0.349 |
3.183 |
-3.993 |
1.148e-03 |
0.231 |
-0.717 |
MCF2 |
MCF.2 cell line derived transforming sequence |
X |
-138491595, -138491595 |
AL033403 |
4168 |
Xq27 |
Hs.387262 |
24 |
guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding intracellular membrane fraction cytoplasm cytosol cytoskeleton intracellular signaling cascade membrane regulation of Rho protein signal transduction |
|
1552790_a_at |
SEC62 |
SEC62 homolog (S. cerevisiae) |
3 |
171167273 |
NM_153039 |
7095 |
3q26.2 |
Hs.622596 |
10 |
receptor activity endoplasmic reticulum cytoskeleton cotranslational protein targeting to membrane protein transporter activity protein transport membrane integral to membrane intracellular protein transmembrane transport |
|
1554610_at |
ANKMY1 |
ankyrin repeat and MYND domain containing 1 |
2 |
-241067511 |
BC033495 |
51281 |
2q37.3 |
Hs.656615 |
4 |
zinc ion binding metal ion binding |
|
226222_at |
KIAA1432 |
KIAA1432 |
9 |
5619326, 5646582 |
AB037853 |
57589 |
9p24.1 |
Hs.211520 |
5 |
membrane integral to membrane |
|
211441_x_at |
-0.296 |
3.690 |
-3.059 |
7.847e-03 |
0.383 |
-2.350 |
CYP3A43 |
cytochrome P450, family 3, subfamily A, polypeptide 43 |
7 |
99263571 |
AF280113 |
64816 |
7q21.1 |
Hs.306220 Hs.654391 Hs.695915 |
17 |
endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding oxidation reduction aromatase activity |
gamma-Hexachlorocyclohexane degradation Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Drug metabolism - other enzymes Metabolic pathways |
208923_at |
0.437 |
8.287 |
2.227 |
4.144e-02 |
0.572 |
-3.749 |
CYFIP1 |
cytoplasmic FMR1 interacting protein 1 |
15 |
20444124, 20507195 |
BC005097 |
23191 |
15q11 |
Hs.26704 |
13 |
ruffle protein binding protein binding cytoplasm multicellular organismal development nervous system development regulation of cell shape synaptosome lamellipodium lamellipodium assembly cell junction cell differentiation ruffle organization synapse Rac GTPase binding perinuclear region of cytoplasm axon extension actin filament binding |
Regulation of actin cytoskeleton |
209787_s_at |
HMGN4 |
high mobility group nucleosomal binding domain 4 |
6 |
26646550 |
BC001282 |
10473 |
6p21.3 |
Hs.236774 |
6 |
chromatin DNA binding nucleus |
|
229767_at |
TBCD |
tubulin folding cofactor D |
17 |
78303228 |
AA012848 |
6904 |
17q25.3 |
Hs.464391 |
18 |
binding microtubule protein folding chaperone binding |
|
237033_at |
-0.262 |
4.818 |
-2.249 |
3.974e-02 |
0.568 |
-3.715 |
FAM159A |
family with sequence similarity 159, member A |
1 |
52871653 |
AI202832 |
348378 |
1p32.3 |
Hs.424589 |
2 |
membrane integral to membrane |
|
222810_s_at |
RASAL2 |
RAS protein activator like 2 |
1 |
176329486, 176577228 |
BF435513 |
9462 |
1q24 |
Hs.549729 Hs.715627 |
11 |
Ras GTPase activator activity intracellular signal transduction regulation of small GTPase mediated signal transduction |
|
1569335_a_at |
STRA6 |
stimulated by retinoic acid gene 6 homolog (mouse) |
15 |
-72273783, -72258862, -72258862, -72258862 |
BC015881 |
64220 |
15q24.1 |
Hs.24553 |
13 |
receptor activity plasma membrane transport integral to membrane protein complex |
|
202243_s_at |
PSMB4 |
proteasome (prosome, macropain) subunit, beta type, 4 |
1 |
149638664 |
NM_002796 |
5692 |
1q21 |
Hs.89545 |
46 |
threonine-type endopeptidase activity nucleus cytoplasm centrosome cytosol proteasome core complex cytoskeleton peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
222862_s_at |
AK5 |
adenylate kinase 5 |
1 |
77520329, 77520874 |
BG169832 |
26289 |
1p31 |
Hs.559718 |
5 |
nucleotide binding adenylate kinase activity ATP binding cytoplasm cytosol cytosol nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ADP biosynthetic process dADP biosynthetic process pyrimidine ribonucleotide biosynthetic process transferase activity nucleoside kinase activity ATP metabolic process |
Purine metabolism Metabolic pathways |
208102_s_at |
PSD |
pleckstrin and Sec7 domain containing |
10 |
-104152365 |
NM_002779 |
5662 |
10q24 |
Hs.154658 |
5 |
signal transducer activity ARF guanyl-nucleotide exchange factor activity cellular_component intracellular signal transduction regulation of ARF protein signal transduction |
Endocytosis |
210482_x_at |
0.340 |
5.612 |
2.498 |
2.444e-02 |
0.513 |
-3.310 |
MAP2K5 |
mitogen-activated protein kinase kinase 5 |
15 |
65622074 |
U71087 |
5607 |
15q23 |
Hs.114198 |
29 |
MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding spindle protein amino acid phosphorylation signal transduction heart development transferase activity |
MAPK signaling pathway Gap junction Neurotrophin signaling pathway |
209553_at |
-0.440 |
7.060 |
-2.587 |
2.046e-02 |
0.495 |
-3.161 |
VPS8 |
vacuolar protein sorting 8 homolog (S. cerevisiae) |
3 |
186012624 |
BC001001 |
23355 |
3q27.2 |
Hs.269263 |
6 |
protein binding zinc ion binding metal ion binding |
|
234268_at |
SLC2A13 |
solute carrier family 2 (facilitated glucose transporter), member 13 |
12 |
-38435091 |
AK000182 |
114134 |
12q12 |
Hs.558595 |
5 |
transporter activity membrane integral to membrane substrate-specific transmembrane transporter activity transmembrane transport |
|
226968_at |
KIF1B |
kinesin family member 1B |
1 |
10193350, 10193350 |
AK023184 |
23095 |
1p36.2 |
Hs.97858 |
33 |
nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm mitochondrion cytoskeleton microtubule microtubule associated complex microtubule-based movement nerve-nerve synaptic transmission neuromuscular synaptic transmission anterograde axon cargo transport ATPase activity kinesin binding cytoplasmic vesicle membrane cytoskeleton-dependent intracellular transport cytoplasmic vesicle |
|
215285_s_at |
0.407 |
4.504 |
3.005 |
8.777e-03 |
0.394 |
-2.445 |
PHTF1 |
putative homeodomain transcription factor 1 |
1 |
-114041346 |
AA927671 |
10745 |
1p13 |
Hs.655824 |
9 |
transcription factor activity nucleus regulation of transcription |
|
1558945_s_at |
CACNA1A |
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
19 |
-13178256 |
BC042451 |
773 |
19p13.2-p13.1 |
Hs.501632 |
126 |
voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated calcium channel activity calcium ion binding protein binding nucleus cytoplasm plasma membrane plasma membrane voltage-gated calcium channel complex ion transport calcium ion transport elevation of cytosolic calcium ion concentration cell death integral to membrane syntaxin binding cell projection |
MAPK signaling pathway Calcium signaling pathway Long-term depression Taste transduction Type II diabetes mellitus |
209385_s_at |
PROSC |
proline synthetase co-transcribed homolog (bacterial) |
8 |
37739258 |
AL136616 |
11212 |
8p11.2 |
Hs.304792 Hs.608177 |
8 |
intracellular cytoplasm |
|
230194_at |
-0.452 |
7.658 |
-3.138 |
6.676e-03 |
0.367 |
-2.213 |
LRPPRC |
leucine-rich PPR-motif containing |
2 |
-43966866 |
AI341076 |
10128 |
2p21 |
Hs.368084 |
15 |
condensed nuclear chromosome DNA binding single-stranded DNA binding RNA binding protein binding nucleus nuclear inner membrane nuclear outer membrane nucleoplasm cytoplasm mitochondrion cytoskeleton transport microtubule binding membrane mitochondrial nucleoid regulation of transcription mitochondrion transport along microtubule perinuclear region of cytoplasm beta-tubulin binding actin filament binding mRNA transport |
|
212563_at |
BOP1 |
block of proliferation 1 |
8 |
-145456863 |
BG491842 |
23246 |
8q24.3 |
Hs.535901 Hs.645279 |
21 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding nucleus nucleoplasm nucleolus rRNA processing cell proliferation ribonucleoprotein complex regulation of cell cycle PeBoW complex |
|
208257_x_at |
PSG1 |
pregnancy specific beta-1-glycoprotein 1 |
19 |
-48063197 |
NM_006905 |
5669 |
19q13.2 |
Hs.709192 |
27 |
extracellular region female pregnancy |
|
238539_at |
HPS3 |
Hermansky-Pudlak syndrome 3 |
3 |
150330060 |
BG163294 |
84343 |
3q24 |
Hs.558314 Hs.591311 |
14 |
cytoplasm organelle organization pigmentation |
|
214294_at |
KIAA0485 |
hypothetical LOC57235 |
|
|
AI122905 |
57235 |
|
Hs.604754 |
1 |
|
|
200764_s_at |
0.252 |
6.736 |
2.137 |
4.926e-02 |
0.590 |
-3.891 |
CTNNA1 |
catenin (cadherin-associated protein), alpha 1, 102kDa |
5 |
138117005 |
AI826881 |
1495 |
5q31 |
Hs.534797 Hs.656653 |
70 |
structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding |
Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
218712_at |
C1orf109 |
chromosome 1 open reading frame 109 |
1 |
-37919828 |
NM_017850 |
54955 |
1p34.3 |
Hs.272673 |
3 |
|
|
206632_s_at |
0.254 |
2.185 |
2.391 |
3.015e-02 |
0.540 |
-3.486 |
APOBEC3B |
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
22 |
37708350 |
NM_004900 |
9582 |
22q13.1-q13.2 |
Hs.226307 |
18 |
RNA binding cellular_component biological_process zinc ion binding hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines metal ion binding |
Atrazine degradation |
222218_s_at |
-0.358 |
5.490 |
-3.411 |
3.800e-03 |
0.319 |
-1.733 |
PILRA |
paired immunoglobin-like type 2 receptor alpha |
7 |
99809003 |
AJ400843 |
29992 |
7q22.1 |
Hs.444407 |
10 |
receptor activity protein binding extracellular region plasma membrane signal transduction integral to membrane interspecies interaction between organisms |
|
1554787_at |
-0.231 |
4.185 |
-2.243 |
4.023e-02 |
0.569 |
-3.725 |
C9orf96 |
chromosome 9 open reading frame 96 |
9 |
135233104 |
BC036504 |
169436 |
9q34.2 |
Hs.159448 |
5 |
nucleotide binding protein kinase activity ATP binding protein amino acid phosphorylation |
|
215437_x_at |
BAZ2A |
bromodomain adjacent to zinc finger domain, 2A |
12 |
-55275646 |
BE513659 |
11176 |
12q24.3-qter |
Hs.314263 |
11 |
chromatin silencing at rDNA DNA binding RNA binding protein binding nucleus chromatin silencing complex nucleolus nucleolus organizer region DNA methylation chromatin remodeling regulation of transcription, DNA-dependent zinc ion binding histone deacetylation transcription regulator activity rDNA heterochromatin metal ion binding histone acetyl-lysine binding |
|
226603_at |
0.528 |
5.327 |
2.782 |
1.382e-02 |
0.441 |
-2.830 |
SAMD9L |
sterile alpha motif domain containing 9-like |
7 |
-92597303 |
BE966604 |
219285 |
7q21.2 |
Hs.489118 |
4 |
|
|
215992_s_at |
RAPGEF2 |
Rap guanine nucleotide exchange factor (GEF) 2 |
4 |
160408447 |
AL117397 |
9693 |
4q32.1 |
Hs.113912 |
14 |
MAPKKK cascade signal transducer activity guanyl-nucleotide exchange factor activity calcium ion binding protein binding intracellular plasma membrane integral to plasma membrane Rap guanyl-nucleotide exchange factor activity cAMP-mediated signaling diacylglycerol binding Rap GTPase activator activity regulation of small GTPase mediated signal transduction |
MAPK signaling pathway |
230228_at |
LOC284297 |
hypothetical LOC284297 |
19 |
60691681 |
W94546 |
284297 |
19q13.42 |
Hs.554182 |
2 |
scavenger receptor activity extracellular region membrane |
|
218652_s_at |
PIGG |
phosphatidylinositol glycan anchor biosynthesis, class G |
4 |
482988 |
NM_017733 |
54872 |
4p16.3 |
Hs.7099 |
8 |
protein binding endoplasmic reticulum endoplasmic reticulum membrane metabolic process membrane integral to membrane preassembly of GPI anchor in ER membrane transferase activity phosphotransferase activity, for other substituted phosphate groups CP2 mannose-ethanolamine phosphotransferase activity |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
200907_s_at |
PALLD |
palladin, cytoskeletal associated protein |
4 |
169654791 |
AU157932 |
23022 |
4q32.3 |
Hs.151220 |
40 |
actin binding protein binding nucleus cytoplasm cytoskeleton actin filament cytoskeleton organization muscle alpha-actinin binding |
|
213864_s_at |
NAP1L1 |
nucleosome assembly protein 1-like 1 |
12 |
-74724938 |
AI985751 |
4673 |
12q21.2 |
Hs.524599 Hs.695185 |
17 |
protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome |
|
218769_s_at |
ANKRA2 |
ankyrin repeat, family A (RFXANK-like), 2 |
5 |
-72883918 |
NM_023039 |
57763 |
5q12-q13 |
Hs.239154 |
6 |
protein binding membrane fraction cytoplasm cytosol cytoskeleton biological_process membrane low-density lipoprotein binding |
|
234665_x_at |
HHLA3 |
HERV-H LTR-associating 3 |
1 |
70593080, 70593080 |
AF126163 |
11147 |
1p31.1 |
Hs.142245 |
5 |
protein binding |
|
1552660_a_at |
C5orf22 |
chromosome 5 open reading frame 22 |
5 |
31568129 |
BC021215 |
55322 |
5p13.3 |
Hs.519246 |
7 |
|
|
235353_at |
KIAA0746 |
KIAA0746 protein |
4 |
-25358146 |
AI887866 |
23231 |
4p15.2 |
Hs.479384 |
5 |
binding membrane integral to membrane |
|
243017_at |
LOC158572 |
hypothetical LOC158572 |
X |
-49528067 |
AA032156 |
158572 |
Xp11.23 |
Hs.408191 |
3 |
|
|
216436_at |
PIK3R4 |
phosphoinositide-3-kinase, regulatory subunit 4 |
3 |
-131880467 |
AK025026 |
30849 |
3q22.1 |
Hs.149032 |
9 |
nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding cellular_component cytosol protein amino acid phosphorylation transferase activity |
Regulation of autophagy |
227022_at |
0.568 |
5.800 |
2.961 |
9.588e-03 |
0.405 |
-2.520 |
GNPDA2 |
glucosamine-6-phosphate deaminase 2 |
4 |
-44398924 |
AI817388 |
132789 |
4p12 |
Hs.21398 |
6 |
glucosamine-6-phosphate deaminase activity cytoplasm carbohydrate metabolic process N-acetylglucosamine metabolic process hydrolase activity |
Amino sugar and nucleotide sugar metabolism Metabolic pathways |
219335_at |
0.577 |
5.634 |
2.576 |
2.089e-02 |
0.497 |
-3.179 |
ARMCX5 |
armadillo repeat containing, X-linked 5 |
X |
101740813 |
NM_022838 |
64860 |
Xq22.1-q22.3 |
Hs.522729 |
5 |
binding |
|
209861_s_at |
METAP2 |
methionyl aminopeptidase 2 |
12 |
94391952 |
U13261 |
10988 |
12q22 |
Hs.444986 |
35 |
aminopeptidase activity cytoplasm proteolysis peptidase activity metalloexopeptidase activity cellular process protein processing peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding |
|
230292_at |
0.452 |
6.050 |
2.624 |
1.901e-02 |
0.488 |
-3.099 |
LOC100131993 |
similar to hCG2020760 |
13 |
|
AA868809 |
100131993 |
13q14.2 |
Hs.709358 |
|
|
|
216248_s_at |
NR4A2 |
nuclear receptor subfamily 4, group A, member 2 |
2 |
-156889189 |
S77154 |
4929 |
2q22-q23 |
Hs.563344 |
76 |
transcription factor activity steroid hormone receptor activity nucleus regulation of transcription, DNA-dependent signal transduction zinc ion binding cellular response to extracellular stimulus sequence-specific DNA binding metal ion binding response to protein stimulus |
|
1569332_at |
C3orf66 |
chromosome 3 open reading frame 66 |
3 |
110379701 |
BC022563 |
677779 |
3q13.13 |
Hs.618669 |
2 |
|
|
225524_at |
0.715 |
6.136 |
3.982 |
1.172e-03 |
0.231 |
-0.734 |
ANTXR2 |
anthrax toxin receptor 2 |
4 |
-81117685, -81041796 |
AU152178 |
118429 |
4q21.21 |
Hs.162963 |
22 |
receptor activity protein binding extracellular region endoplasmic reticulum plasma membrane integral to membrane metal ion binding |
|
222436_s_at |
0.223 |
8.492 |
2.341 |
3.322e-02 |
0.552 |
-3.566 |
VPS24 |
vacuolar protein sorting 24 homolog (S. cerevisiae) |
2 |
-86584063 |
AF219226 |
51652 |
2p24.3-p24.1 |
Hs.591582 |
25 |
protein binding cytoplasm endosome cytosol cell cycle protein transport membrane late endosome membrane cell division |
Endocytosis |
235931_at |
0.445 |
3.428 |
2.200 |
4.366e-02 |
0.578 |
-3.792 |
FAM119A |
family with sequence similarity 119, member A |
2 |
-208182083, -208182083 |
AI332764 |
151194 |
2q33.3 |
Hs.664764 |
2 |
membrane integral to membrane |
|
211006_s_at |
1.741 |
6.748 |
2.428 |
2.801e-02 |
0.529 |
-3.424 |
KCNB1 |
potassium voltage-gated channel, Shab-related subfamily, member 1 |
20 |
-47421911 |
L02840 |
3745 |
20q13.2 |
Hs.84244 |
28 |
voltage-gated ion channel activity voltage-gated potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex membrane integral to membrane potassium ion binding |
Taste transduction |
1565583_at |
ZSCAN5A |
zinc finger and SCAN domain containing 5A |
19 |
-61424490 |
AW469591 |
79149 |
19q13.43 |
Hs.177688 |
3 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
209652_s_at |
PGF |
placental growth factor |
14 |
-74478290 |
BC001422 |
5228 |
14q24-q31 |
Hs.252820 |
79 |
angiogenesis extracellular region signal transduction cell-cell signaling multicellular organismal development growth factor activity heparin binding positive regulation of cell proliferation membrane cell differentiation |
mTOR signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer |
217842_at |
LUC7L2 |
LUC7-like 2 (S. cerevisiae) |
7 |
138695173 |
NM_016019 |
51631 |
7q34 |
Hs.718441 |
16 |
zinc ion binding enzyme binding metal ion binding |
|
213857_s_at |
CD47 |
CD47 molecule |
3 |
-109244630 |
BG230614 |
961 |
3q13.1-q13.2 |
Hs.446414 |
68 |
protein binding plasma membrane plasma membrane integral to plasma membrane cell adhesion integrin-mediated signaling pathway positive regulation of cell proliferation positive regulation of cell-cell adhesion positive regulation of T cell activation thrombospondin receptor activity |
ECM-receptor interaction |
243900_at |
WDR38 |
WD repeat domain 38 |
9 |
126655575 |
AI190548 |
401551 |
9q33.3 |
Hs.343383 |
1 |
|
|
203674_at |
HELZ |
helicase with zinc finger |
17 |
-62497015 |
NM_014877 |
9931 |
17q24.2 |
Hs.370140 Hs.569824 Hs.596366 |
8 |
nucleotide binding nucleic acid binding helicase activity ATP binding nucleus zinc ion binding hydrolase activity metal ion binding |
|
232940_s_at |
MLL3 |
myeloid/lymphoid or mixed-lineage leukemia 3 |
7 |
-151462942 |
AK025911 |
58508 |
7q36.1 |
Hs.647120 |
21 |
DNA binding protein binding nucleus regulation of transcription, DNA-dependent intracellular signaling cascade methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding |
|
203167_at |
TIMP2 |
TIMP metallopeptidase inhibitor 2 |
17 |
-74360653 |
NM_003255 |
7077 |
17q25 |
Hs.633514 |
168 |
enzyme inhibitor activity integrin binding protein binding extracellular region basement membrane enzyme activator activity metalloendopeptidase inhibitor activity negative regulation of cell proliferation cell surface regulation of cAMP metabolic process regulation of MAPKKK cascade regulation of neuron differentiation |
|
200830_at |
PSMD2 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 |
3 |
185499715 |
NM_002808 |
5708 |
3q27.1 |
Hs.518464 |
45 |
proteasome complex protein binding cytosol proteasome regulatory particle enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
206409_at |
-0.262 |
4.127 |
-3.297 |
4.809e-03 |
0.339 |
-1.933 |
TIAM1 |
T-cell lymphoma invasion and metastasis 1 |
21 |
-31412606 |
NM_003253 |
7074 |
21q22.1 21q22.11 |
Hs.517228 |
49 |
receptor signaling protein activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding phospholipid binding intracellular plasma membrane small GTPase mediated signal transduction regulation of Rho protein signal transduction ephrin receptor binding ephrin receptor signaling pathway positive regulation of axonogenesis |
Chemokine signaling pathway Regulation of actin cytoskeleton |
204592_at |
-0.355 |
4.637 |
-2.403 |
2.945e-02 |
0.536 |
-3.466 |
DLG4 |
discs, large homolog 4 (Drosophila) |
17 |
-7033935, -7033933 |
NM_001365 |
1742 |
17p13.1 |
Hs.463928 |
119 |
cytoplasm plasma membrane protein complex assembly signal transduction synaptic transmission nervous system development learning protein C-terminus binding postsynaptic density synaptic vesicle maturation synaptosome cell junction cortical cytoskeleton extrinsic to internal side of plasma membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex synapse postsynaptic membrane regulation of long-term neuronal synaptic plasticity |
Huntington's disease |
225144_at |
BMPR2 |
bone morphogenetic protein receptor, type II (serine/threonine kinase) |
2 |
202949294 |
AI457436 |
659 |
2q33-q34 |
Hs.471119 |
106 |
nucleotide binding magnesium ion binding mesoderm formation negative regulation of systemic arterial blood pressure protein serine/threonine kinase activity receptor activity transforming growth factor beta receptor activity protein binding ATP binding plasma membrane plasma membrane integral to plasma membrane caveola transcription from RNA polymerase II promoter protein amino acid phosphorylation cellular response to starvation anterior/posterior pattern formation regulation of lung blood pressure regulation of lung blood pressure transferase activity manganese ion binding positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway BMP signaling pathway BMP signaling pathway regulation of cell proliferation positive regulation of osteoblast differentiation negative regulation of vasoconstriction vascular endothelial growth factor receptor signaling pathway lung alveolus development |
Cytokine-cytokine receptor interaction TGF-beta signaling pathway |
1564709_at |
LOC286238 |
hypothetical protein LOC286238 |
9 |
-90451913 |
AK098532 |
286238 |
9q22.1 |
Hs.434185 |
1 |
|
|
214733_s_at |
YIPF1 |
Yip1 domain family, member 1 |
1 |
-54089993 |
AL031427 |
54432 |
1p33-p32.1 |
Hs.11923 |
9 |
membrane integral to membrane transport vesicle |
|
226324_s_at |
-0.244 |
5.946 |
-2.848 |
1.210e-02 |
0.426 |
-2.717 |
IFT172 |
intraflagellar transport 172 homolog (Chlamydomonas) |
2 |
-27520743 |
AB033005 |
26160 |
2p23.3 |
Hs.127401 |
4 |
neural tube formation protein binding cilium smoothened signaling pathway multicellular organismal development determination of left/right symmetry dorsal/ventral pattern formation protein processing cilium assembly |
|
204105_s_at |
0.501 |
4.360 |
2.681 |
1.694e-02 |
0.468 |
-3.002 |
NRCAM |
neuronal cell adhesion molecule |
7 |
-107575317, -107575317 |
NM_005010 |
4897 |
7q31.1-q31.2 |
Hs.21422 |
29 |
neuron migration protein binding plasma membrane integral to plasma membrane axonal fasciculation synaptogenesis central nervous system development external side of plasma membrane cell-cell adhesion ankyrin binding regulation of axon extension neuron projection clustering of voltage-gated sodium channels positive regulation of neuron differentiation |
Cell adhesion molecules (CAMs) |
231995_at |
C9orf82 |
chromosome 9 open reading frame 82 |
9 |
-26830682 |
AF131768 |
79886 |
9p21.2 |
Hs.178357 |
10 |
|
|
201899_s_at |
UBE2A |
ubiquitin-conjugating enzyme E2A (RAD6 homolog) |
X |
118592526, 118598325 |
NM_003336 |
7319 |
Xq24-q25 |
Hs.379466 |
16 |
nucleotide binding chromatin ubiquitin-protein ligase activity ATP binding postreplication repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus positive regulation of cell proliferation response to UV ligase activity ubiquitin protein ligase binding histone H2A ubiquitination post-translational protein modification regulation of protein metabolic process protein autoubiquitination |
Ubiquitin mediated proteolysis |
226313_at |
C10orf35 |
chromosome 10 open reading frame 35 |
10 |
71060008 |
H49529 |
219738 |
10q22.1 |
Hs.522992 |
5 |
protein binding membrane integral to membrane |
|
238681_at |
GDPD1 |
glycerophosphodiester phosphodiesterase domain containing 1 |
17 |
54652615 |
R46180 |
284161 |
17q22 |
Hs.631744 |
6 |
glycerol metabolic process lipid metabolic process glycerophosphodiester phosphodiesterase activity membrane integral to membrane hydrolase activity |
|
228235_at |
0.814 |
4.217 |
2.594 |
2.016e-02 |
0.492 |
-3.149 |
MGC16121 |
hypothetical protein MGC16121 |
X |
-133505073 |
BE048571 |
84848 |
Xq26.3 |
Hs.416379 Hs.656866 |
2 |
|
|
208777_s_at |
PSMD11 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
17 |
27795614 |
AF001212 |
5717 |
17q11.2 |
Hs.655396 |
41 |
proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
221172_at |
C7orf69 |
chromosome 7 open reading frame 69 |
7 |
47801413 |
NM_025031 |
80099 |
7p12.3 |
Hs.287647 |
2 |
extracellular region |
|
206180_x_at |
ZNF747 |
zinc finger protein 747 |
16 |
-30450279 |
NM_023931 |
65988 |
16p11.2 |
Hs.592032 |
3 |
nucleic acid binding intracellular regulation of transcription, DNA-dependent |
|
228186_s_at |
0.700 |
8.382 |
3.488 |
3.241e-03 |
0.306 |
-1.598 |
RSPO3 |
R-spondin 3 homolog (Xenopus laevis) |
6 |
127481740 |
BF589322 |
84870 |
6q22.33 |
Hs.135254 |
10 |
extracellular region heparin binding Wnt receptor signaling pathway response to stimulus |
|
1554584_at |
LRRC48 |
leucine rich repeat containing 48 |
17 |
17816851, 17816851 |
BC040276 |
83450 |
17p11.2 |
Hs.579264 |
11 |
protein binding cytoplasm |
|
206109_at |
FUT1 |
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
19 |
-53943079 |
NM_000148 |
2523 |
19q13.3 |
Hs.69747 |
30 |
membrane fraction Golgi apparatus integral to plasma membrane carbohydrate metabolic process protein amino acid glycosylation galactoside 2-alpha-L-fucosyltransferase activity fucosyltransferase activity membrane transferase activity, transferring glycosyl groups L-fucose catabolic process |
Glycosphingolipid biosynthesis - lacto and neolacto series Glycosphingolipid biosynthesis - globo series Metabolic pathways |
209690_s_at |
DOK4 |
docking protein 4 |
16 |
-56063370 |
BF591163 |
55715 |
16q21 |
Hs.279832 |
11 |
MAPKKK cascade transmembrane receptor protein tyrosine kinase signaling protein activity insulin receptor binding transmembrane receptor protein tyrosine kinase signaling pathway nervous system development |
|
225701_at |
AKNA |
AT-hook transcription factor |
9 |
-116136254 |
AK024431 |
80709 |
9q32 |
Hs.494895 |
5 |
DNA binding nucleus regulation of transcription |
|
1560219_at |
-0.310 |
5.018 |
-3.350 |
4.312e-03 |
0.328 |
-1.841 |
ASB3 |
ankyrin repeat and SOCS box-containing 3 |
2 |
-53750621 |
AI076068 |
51130 |
2p16-p14 |
Hs.40763 |
10 |
intracellular signaling cascade modification-dependent protein catabolic process |
|
225818_s_at |
TBRG1 |
transforming growth factor beta regulator 1 |
11 |
123997951 |
BG286461 |
84897 |
11q24.2 |
Hs.436410 |
11 |
DNA binding protein binding nucleus DNA replication cell cycle cell cycle arrest negative regulation of cell proliferation nucleolus to nucleoplasm transport protein stabilization |
|
221166_at |
FGF23 |
fibroblast growth factor 23 |
12 |
-4347653 |
NM_020638 |
8074 |
12p13.3 |
Hs.287370 |
83 |
extracellular region extracellular region extracellular space growth factor activity fibroblast growth factor receptor signaling pathway cell differentiation regulation of bone mineralization cellular phosphate ion homeostasis |
MAPK signaling pathway Regulation of actin cytoskeleton Pathways in cancer Melanoma |
233988_x_at |
SCUBE1 |
signal peptide, CUB domain, EGF-like 1 |
22 |
-41929173 |
Z82214 |
80274 |
22q13 |
Hs.133995 |
7 |
calcium ion binding extracellular region extracellular space plasma membrane inflammatory response adult heart development blood coagulation post-embryonic development external side of plasma membrane extrinsic to plasma membrane identical protein binding endothelial cell differentiation protein heterodimerization activity protein homooligomerization |
|
241433_at |
RCOR3 |
REST corepressor 3 |
1 |
209499330, 209499330, 209499911 |
AI023806 |
55758 |
1q32.2 |
Hs.356399 |
10 |
DNA binding protein binding nucleus nucleolus cytoplasm regulation of transcription |
|
223675_s_at |
VEZT |
vezatin, adherens junctions transmembrane protein |
12 |
94135652 |
AF216644 |
55591 |
12q22 |
Hs.24135 |
8 |
acrosomal vesicle nucleus plasma membrane adherens junction integral to membrane cell junction |
|
1569111_at |
SOX13 |
SRY (sex determining region Y)-box 13 |
1 |
202308868 |
BC040649 |
9580 |
1q32 |
Hs.201671 |
19 |
transcription factor activity nucleus anatomical structure morphogenesis sequence-specific DNA binding regulation of transcription |
|
225113_at |
AGPS |
alkylglycerone phosphate synthase |
2 |
177965716 |
BF688144 |
8540 |
2q31.2 |
Hs.516543 |
19 |
peroxisome peroxisomal membrane cytosol alkylglycerone-phosphate synthase activity lipid biosynthetic process membrane oxidoreductase activity transferase activity FAD binding |
Ether lipid metabolism Metabolic pathways |
219516_at |
TRPV4 |
transient receptor potential cation channel, subfamily V, member 4 |
12 |
-108705276 |
NM_021625 |
59341 |
12q24.1 |
Hs.506713 |
50 |
calcium channel activity calcium ion binding calmodulin binding plasma membrane ion transport calcium ion transport calcium ion transport cellular calcium ion homeostasis cell volume homeostasis elevation of cytosolic calcium ion concentration osmosensory signaling pathway response to mechanical stimulus integral to membrane identical protein binding |
|
212373_at |
FEM1B |
fem-1 homolog b (C. elegans) |
15 |
66357194 |
AW139179 |
10116 |
15q22 |
Hs.362733 |
9 |
ubiquitin-protein ligase activity death receptor binding death receptor binding cellular_component cytoplasm induction of apoptosis modification-dependent protein catabolic process regulation of apoptosis regulation of ubiquitin-protein ligase activity |
|
206417_at |
-0.684 |
5.457 |
-2.918 |
1.048e-02 |
0.418 |
-2.596 |
CNGA1 |
cyclic nucleotide gated channel alpha 1 |
4 |
-47632750, -47632750 |
NM_000087 |
1259 |
4p12-cen |
Hs.1323 |
15 |
nucleotide binding photoreceptor outer segment ion channel activity membrane fraction cytoplasm integral to plasma membrane ion transport spermatogenesis visual perception membrane intracellular cyclic nucleotide activated cation channel complex cGMP binding response to stimulus |
|
207142_at |
KCNJ3 |
potassium inwardly-rectifying channel, subfamily J, member 3 |
2 |
155263338 |
NM_002239 |
3760 |
2q24.1 |
Hs.591606 |
24 |
voltage-gated ion channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex external side of plasma membrane G-protein activated inward rectifier potassium channel activity membrane integral to membrane T-tubule potassium ion binding |
|
222760_at |
ZNF703 |
zinc finger protein 703 |
8 |
37672458 |
BG290193 |
80139 |
8p11.23 |
Hs.288042 |
5 |
intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
1554638_at |
ZFYVE16 |
zinc finger, FYVE domain containing 16 |
5 |
79739593 |
BC032227 |
9765 |
5q14 |
Hs.482660 Hs.660410 |
15 |
protein binding phosphatidylinositol binding cytoplasm protein targeting to lysosome signal transduction zinc ion binding protein transporter activity membrane vesicle organization endosome transport regulation of endocytosis BMP signaling pathway early endosome membrane metal ion binding |
TGF-beta signaling pathway |
214889_at |
2.028 |
5.527 |
5.187 |
1.057e-04 |
0.162 |
1.266 |
FAM149A |
family with sequence similarity 149, member A |
4 |
187302988, 187307320 |
AL080065 |
25854 |
4q35.1 |
Hs.357025 |
3 |
|
|
205759_s_at |
SULT2B1 |
sulfotransferase family, cytosolic, 2B, member 1 |
19 |
53747240, 53770804 |
NM_004605 |
6820 |
19q13.3 |
Hs.369331 |
29 |
alcohol sulfotransferase activity protein binding cytoplasm cytosol lipid metabolic process steroid metabolic process transferase activity steroid sulfotransferase activity |
Androgen and estrogen metabolism Sulfur metabolism |
208671_at |
SERINC1 |
serine incorporator 1 |
6 |
-122806191 |
AF164794 |
57515 |
6q22.31 |
Hs.146668 |
9 |
endoplasmic reticulum endoplasmic reticulum membrane plasma membrane lipid metabolic process phosphatidylserine metabolic process sphingolipid metabolic process phospholipid biosynthetic process L-serine transmembrane transporter activity L-serine transport integral to membrane positive regulation of transferase activity |
|
201485_s_at |
RCN2 |
reticulocalbin 2, EF-hand calcium binding domain |
15 |
75011016 |
BC004892 |
5955 |
15q23 |
Hs.79088 |
10 |
calcium ion binding protein binding endoplasmic reticulum endoplasmic reticulum lumen |
|
229994_at |
NFIA |
nuclear factor I/A |
1 |
61315533, 61320121, 61320567 |
R45950 |
4774 |
1p31.3-p31.2 |
Hs.594180 Hs.710546 |
20 |
transcription factor activity intracellular nucleus nucleus cytoplasm plasma membrane DNA replication regulation of transcription, DNA-dependent transcription factor binding viral genome replication |
|
208205_at |
PCDHA9 |
protocadherin alpha 9 |
5 |
140207540, 140207540 |
NM_014005 |
9752 |
5q31 |
Hs.199343 |
11 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane |
|
212576_at |
MGRN1 |
mahogunin, ring finger 1 |
16 |
4614826 |
AB011116 |
23295 |
16p13.3 |
Hs.526494 |
10 |
protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding |
Ubiquitin mediated proteolysis |
200614_at |
0.305 |
9.672 |
2.686 |
1.678e-02 |
0.467 |
-2.994 |
CLTC |
clathrin, heavy chain (Hc) |
17 |
55051831 |
NM_004859 |
1213 |
17q11-qter |
Hs.491351 Hs.663896 |
77 |
structural molecule activity protein binding plasma membrane intracellular protein transport vesicle-mediated transport clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit cytoplasmic vesicle melanosome |
Lysosome Endocytosis Huntington's disease |
210872_x_at |
0.521 |
4.638 |
3.920 |
1.331e-03 |
0.245 |
-0.842 |
GAS7 |
growth arrest-specific 7 |
17 |
-9754650, -9754650, -9754650, -9754650 |
BC001152 |
8522 |
17p13.1 |
Hs.462214 |
11 |
transcription factor activity protein binding cytoplasm cell cycle arrest multicellular organismal development nervous system development cell differentiation |
|
212497_at |
MAPK1IP1L |
mitogen-activated protein kinase 1 interacting protein 1-like |
14 |
54588114 |
AI554879 |
93487 |
14q22.3 |
Hs.594338 Hs.619374 |
8 |
|
|
234647_at |
KCNIP3 |
Kv channel interacting protein 3, calsenilin |
2 |
95326798, 95376494 |
AK026052 |
30818 |
2q21.1 |
Hs.437376 |
43 |
negative regulation of transcription from RNA polymerase II promoter DNA binding transcription corepressor activity voltage-gated ion channel activity potassium channel activity calcium ion binding nucleus cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane ion transport potassium ion transport apoptosis signal transduction behavior protein C-terminus binding specific transcriptional repressor activity sensory perception of pain potassium ion binding regulation of neuron apoptosis regulation of transcription response to pain calcium-dependent protein binding |
|
217325_at |
KRT3 |
keratin 3 |
12 |
-51469735 |
X05421 |
3850 |
12q12-q13 |
Hs.680652 |
9 |
structural molecule activity structural molecule activity epithelial cell differentiation keratin filament intermediate filament cytoskeleton organization |
|
209555_s_at |
CD36 |
CD36 molecule (thrombospondin receptor) |
7 |
80069439, 80105767, 80105767, 80113580, 80113697 |
M98399 |
948 |
7q11.2 |
Hs.120949 |
173 |
positive regulation of cell-matrix adhesion low-density lipoprotein receptor activity membrane fraction Golgi apparatus plasma membrane integral to plasma membrane lipid metabolic process transport cell adhesion nitric oxide mediated signal transduction blood coagulation high-density lipoprotein binding lipid binding cell surface cell surface positive regulation of foam cell differentiation plasma membrane long-chain fatty acid transport lipid storage cGMP-mediated signaling cholesterol transport platelet alpha granule membrane lipoprotein particle clearance lipoprotein catabolic process lipoprotein transport apoptotic cell clearance transforming growth factor beta binding thrombospondin receptor activity |
PPAR signaling pathway ECM-receptor interaction Hematopoietic cell lineage Adipocytokine signaling pathway |
207303_at |
-0.204 |
3.652 |
-2.203 |
4.343e-02 |
0.578 |
-3.788 |
PDE1C |
phosphodiesterase 1C, calmodulin-dependent 70kDa |
7 |
-31795771 |
NM_005020 |
5137 |
7p14.3 |
Hs.655694 |
10 |
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity |
Purine metabolism Calcium signaling pathway Olfactory transduction |
201183_s_at |
CHD4 |
chromodomain helicase DNA binding protein 4 |
12 |
-6549508 |
AI613273 |
1108 |
12p13 |
Hs.162233 |
32 |
nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter transcription factor binding zinc ion binding chromatin modification hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides regulation of transcription metal ion binding |
|
212379_at |
GART |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
21 |
-33818186, -33798108, -33798108, -33798108 |
BE966876 |
2618 |
21q22.1 21q22.11 |
Hs.473648 |
23 |
nucleotide binding phosphoribosylamine-glycine ligase activity phosphoribosylamine-glycine ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylglycinamide formyltransferase activity protein binding ATP binding cytoplasm cytosol purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process methyltransferase activity biosynthetic process purine base biosynthetic process transferase activity ligase activity manganese ion binding metal ion binding |
Purine metabolism One carbon pool by folate Metabolic pathways |
1557283_a_at |
ZNF519 |
zinc finger protein 519 |
18 |
-14094723 |
BC037787 |
162655 |
18p11.21 |
Hs.352635 |
4 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
206273_at |
SLMO1 |
slowmo homolog 1 (Drosophila) |
18 |
12397894 |
NM_006553 |
10650 |
18p11.21 |
Hs.514718 |
3 |
|
|
222679_s_at |
DCUN1D1 |
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) |
3 |
-184143252 |
AW468880 |
54165 |
3q26.3 |
Hs.715661 |
16 |
molecular_function cellular_component biological_process modification-dependent protein catabolic process |
|
202873_at |
-0.190 |
4.301 |
-2.226 |
4.154e-02 |
0.572 |
-3.751 |
ATP6V1C1 |
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
8 |
104102423 |
BF034973 |
528 |
8q22.3 |
Hs.86905 |
19 |
transporter activity protein binding plasma membrane ion transport ATP synthesis coupled proton transport proton transport proton-transporting two-sector ATPase complex hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances proton-transporting V-type ATPase, V1 domain proton-transporting ATPase activity, rotational mechanism |
Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection |
213726_x_at |
TUBB2C |
tubulin, beta 2C |
9 |
139255531 |
AA515698 |
10383 |
9q34 |
Hs.433615 |
25 |
nucleotide binding GTPase activity structural molecule activity GTP binding cytoskeleton microtubule cell motion microtubule-based movement natural killer cell mediated cytotoxicity MHC class I protein binding protein complex unfolded protein binding protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
206375_s_at |
0.683 |
9.876 |
2.891 |
1.108e-02 |
0.425 |
-2.643 |
HSPB3 |
heat shock 27kDa protein 3 |
5 |
53787201 |
NM_006308 |
8988 |
5q11.2 |
Hs.41707 |
6 |
response to unfolded protein response to heat |
|
1566207_at |
TCEA1 |
transcription elongation factor A (SII), 1 |
8 |
-55041668 |
BQ286789 |
6917 |
8q11.2 |
Hs.491745 |
32 |
DNA binding transcription elongation regulator activity translation elongation factor activity protein binding nucleus nucleoplasm nucleoplasm RNA elongation zinc ion binding general RNA polymerase II transcription factor activity erythrocyte differentiation positive regulation of transcription from RNA polymerase II promoter metal ion binding |
|
234644_x_at |
TNFRSF10C |
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
8 |
23016378 |
AK026079 |
8794 |
8p22-p21 |
Hs.655801 |
43 |
transmembrane receptor activity plasma membrane integral to plasma membrane apoptosis signal transduction anchored to membrane |
Cytokine-cytokine receptor interaction Apoptosis Natural killer cell mediated cytotoxicity |
209135_at |
ASPH |
aspartate beta-hydroxylase |
8 |
-62739837, -62699648, -62699648, -62575669 |
AF289489 |
444 |
8q12.1 |
Hs.591874 |
24 |
peptide-aspartate beta-dioxygenase activity binding iron ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane muscle contraction pattern specification process negative regulation of cell proliferation structural constituent of muscle electron carrier activity membrane integral to membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen peptidyl-amino acid modification integral to endoplasmic reticulum membrane limb morphogenesis peptidyl-aspartic acid hydroxylation oxidation reduction palate development face morphogenesis |
|
222826_at |
PLDN |
pallidin homolog (mouse) |
15 |
43666708 |
BC004819 |
26258 |
15q21.1 |
Hs.719102 |
17 |
cellular_component cytoplasm endosome membrane fusion blood coagulation membrane synaptic vesicle docking during exocytosis melanocyte differentiation syntaxin-13 binding positive regulation of natural killer cell activation secretion of lysosomal enzymes identical protein binding pigmentation |
|
233544_at |
GNL1 |
guanine nucleotide binding protein-like 1 |
6 |
-30621672, -1962248, -1760543 |
X66436 |
2794 |
6p21.3 |
Hs.83147 |
5 |
nucleotide binding T cell mediated immunity structural molecule activity GTP binding extracellular space intracellular response to DNA damage stimulus signal transduction |
|
226123_at |
CHD7 |
chromodomain helicase DNA binding protein 7 |
8 |
61753892 |
AI870918 |
55636 |
8q12.1-q12.2 |
Hs.20395 |
36 |
nucleotide binding chromatin skeletal system development blood vessel development in utero embryonic development heart morphogenesis DNA binding chromatin binding helicase activity ATP binding nucleus chromatin assembly or disassembly central nervous system development adult heart development sensory perception of sound locomotory behavior adult walking behavior blood circulation chromatin modification hydrolase activity cranial nerve development T cell differentiation female genitalia development embryonic hindlimb morphogenesis positive regulation of multicellular organism growth inner ear morphogenesis nose development regulation of transcription cognition palate development retina development in camera-type eye regulation of growth hormone secretion limb development face development |
|
212325_at |
LIMCH1 |
LIM and calponin homology domains 1 |
4 |
41057560, 41309675 |
AK027231 |
22998 |
4p13 |
Hs.335163 |
10 |
actin binding zinc ion binding actomyosin structure organization metal ion binding |
|
212004_at |
C1orf144 |
chromosome 1 open reading frame 144 |
1 |
16566169 |
AL050028 |
26099 |
1p36.13 |
Hs.252967 |
2 |
|
|
216561_x_at |
SOX5 |
SRY (sex determining region Y)-box 5 |
12 |
-23576497, -23576497, -23576497 |
AF032454 |
6660 |
12p12.1 |
Hs.657542 |
24 |
transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription |
|
214230_at |
0.325 |
3.438 |
2.762 |
1.438e-02 |
0.447 |
-2.864 |
CDC42 |
cell division cycle 42 (GTP binding protein, 25kDa) |
1 |
22251706, 22251706 |
R37664 |
998 |
1p36.1 |
Hs.690198 |
265 |
nucleotide binding GTPase activity protein binding GTP binding intracellular cytoplasm cytosol plasma membrane establishment or maintenance of cell polarity small GTPase mediated signal transduction actin cytoskeleton organization filopodium macrophage differentiation positive regulation of pseudopodium assembly negative regulation of protein complex assembly |
MAPK signaling pathway Chemokine signaling pathway Endocytosis Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Tight junction T cell receptor signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Pathogenic Escherichia coli infection - EHEC Pathways in cancer Renal cell carcinoma Pancreatic cancer |
212511_at |
PICALM |
phosphatidylinositol binding clathrin assembly protein |
11 |
-85346132 |
AI766247 |
8301 |
11q14 |
Hs.163893 |
22 |
phospholipid binding phosphatidylinositol binding Golgi apparatus coated pit protein complex assembly receptor-mediated endocytosis membrane clathrin coat clathrin-coated vesicle clathrin binding cytoplasmic vesicle clathrin coat assembly |
|
226469_s_at |
GGT7 |
gamma-glutamyltransferase 7 |
20 |
-32896183 |
AL049709 |
2686 |
20q11.22 |
Hs.433738 |
9 |
gamma-glutamyltransferase activity glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity |
Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways |
228184_at |
DISP1 |
dispatched homolog 1 (Drosophila) |
1 |
221168405 |
AK023679 |
84976 |
1q41 |
Hs.528817 |
5 |
multicellular organismal development hedgehog receptor activity membrane integral to membrane |
|
1553634_a_at |
FLJ40852 |
hypothetical LOC285962 |
7 |
-141050606 |
NM_173677 |
285962 |
7q34 |
Hs.17589 |
2 |
|
|
220397_at |
MDM1 |
Mdm1 nuclear protein homolog (mouse) |
12 |
-67005051, -66974612 |
NM_020128 |
56890 |
12q15 |
Hs.655702 |
6 |
nucleus |
|
225613_at |
MAST4 |
microtubule associated serine/threonine kinase family member 4 |
5 |
65927931, 66160359 |
AI096389 |
375449 |
5q12.3 |
Hs.595458 |
5 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
211714_x_at |
0.616 |
9.583 |
2.313 |
3.508e-02 |
0.555 |
-3.612 |
TUBB |
tubulin, beta |
6 |
30796135, 2136731, 1935034 |
BC005838 |
203068 |
6p21.33 |
Hs.636480 Hs.706187 Hs.714425 |
39 |
nucleotide binding GTPase activity structural constituent of cytoskeleton GTP binding cytoskeleton microtubule cell motion microtubule-based movement flotillin complex natural killer cell mediated cytotoxicity MHC class I protein binding spindle assembly protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
215366_at |
SNX13 |
sorting nexin 13 |
7 |
-17796910 |
AL353943 |
23161 |
7p21.1 |
Hs.487648 |
10 |
signal transducer activity protein binding cell communication negative regulation of signal transduction protein transport phosphoinositide binding |
|
219623_at |
ACTR5 |
ARP5 actin-related protein 5 homolog (yeast) |
20 |
36810510 |
NM_024855 |
79913 |
20q11.23 |
Hs.371585 |
7 |
protein binding ATP binding regulation of transcription |
|
207105_s_at |
PIK3R2 |
phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
19 |
18125015 |
NM_005027 |
5296 |
19q13.2-q13.4 |
Hs.371344 |
68 |
protein binding intracellular cytosol phosphoinositide 3-kinase complex signal transduction 1-phosphatidylinositol-3-kinase activity negative regulation of anti-apoptosis phosphoinositide 3-kinase regulator activity |
ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer |
1553711_a_at |
-0.230 |
4.566 |
-2.309 |
3.536e-02 |
0.556 |
-3.618 |
C4orf39 |
chromosome 4 open reading frame 39 |
4 |
166097549 |
NM_153027 |
152756 |
4q32.3 |
Hs.178648 Hs.710449 |
2 |
|
|
1558212_at |
FLJ35024 |
hypothetical LOC401491 |
9 |
-2525654 |
BC004474 |
401491 |
9p24.2 |
Hs.416043 |
2 |
|
|
202136_at |
0.299 |
9.463 |
3.036 |
8.237e-03 |
0.387 |
-2.391 |
ZMYND11 |
zinc finger, MYND domain containing 11 |
10 |
170423, 170423 |
BE250417 |
10771 |
10p14 |
Hs.292265 |
17 |
negative regulation of transcription from RNA polymerase II promoter DNA binding protein binding nucleus cell cycle zinc ion binding cell proliferation regulation of transcription metal ion binding |
|
203484_at |
SEC61G |
Sec61 gamma subunit |
7 |
-54787433 |
NM_014302 |
23480 |
7p11.2 |
Hs.488282 |
10 |
endoplasmic reticulum protein targeting P-P-bond-hydrolysis-driven protein transmembrane transporter activity membrane integral to membrane intracellular protein transmembrane transport |
Vibrio cholerae infection |
215146_s_at |
TTC28 |
tetratricopeptide repeat domain 28 |
22 |
-26704003 |
AB028966 |
23331 |
22q12.1 |
Hs.387856 Hs.719265 |
6 |
binding |
|
218331_s_at |
C10orf18 |
chromosome 10 open reading frame 18 |
10 |
5766806 |
NM_017782 |
54906 |
10p15.1 |
Hs.699500 |
4 |
|
|
240618_at |
PTPRA |
protein tyrosine phosphatase, receptor type, A |
20 |
2792840, 2802141, 2851852 |
BF439479 |
5786 |
20p13 |
Hs.269577 |
58 |
transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid phosphorylation protein amino acid dephosphorylation membrane hydrolase activity |
|
211955_at |
IPO5 |
importin 5 |
13 |
97403929 |
NM_002271 |
3843 |
13q32.2 |
Hs.712598 |
53 |
protein import into nucleus, docking GTPase inhibitor activity protein binding nucleus nuclear pore nucleolus cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport Ran GTPase binding protein transporter activity interspecies interaction between organisms |
|
219547_at |
COX15 |
COX15 homolog, cytochrome c oxidase assembly protein (yeast) |
10 |
-101458494 |
NM_004376 |
1355 |
10q24 |
Hs.28326 |
9 |
catalytic activity cytochrome-c oxidase activity mitochondrial respiratory chain mitochondrial electron transport, cytochrome c to oxygen protein complex assembly heme a biosynthetic process respiratory gaseous exchange respiratory chain complex IV assembly membrane integral to membrane mitochondrial part cellular respiration oxidation reduction |
Oxidative phosphorylation Porphyrin and chlorophyll metabolism Metabolic pathways |
218423_x_at |
VPS54 |
vacuolar protein sorting 54 homolog (S. cerevisiae) |
2 |
-63973170 |
NM_016516 |
51542 |
2p13-p14 |
Hs.48499 |
8 |
protein binding protein transport retrograde transport, endosome to Golgi |
|
1553023_a_at |
NOX5 |
NADPH oxidase, EF-hand calcium binding domain 5 |
15 |
67009917 |
NM_024505 |
79400 |
15q23 |
Hs.657932 |
27 |
cytokinesis ion channel activity calcium ion binding ion transport induction of apoptosis cell proliferation electron carrier activity regulation of proton transport hydrogen ion channel activity hydrogen ion channel activity membrane integral to membrane superoxide-generating NADPH oxidase activity superoxide-generating NADPH oxidase activity oxidoreductase activity heme binding electron transport chain superoxide anion generation superoxide anion generation regulation of fusion of sperm to egg plasma membrane FAD binding NADP or NADPH binding cytokine secretion |
|
220975_s_at |
C1QTNF1 |
C1q and tumor necrosis factor related protein 1 |
17 |
74531845, 74542066 |
NM_030968 |
114897 |
17q25.3 |
Hs.201398 |
11 |
extracellular region |
|
241533_at |
LOC731656 |
hypothetical LOC731656 |
1 |
|
AV652367 |
731656 |
|
Hs.702477 |
1 |
|
|
225308_s_at |
0.383 |
6.133 |
2.472 |
2.568e-02 |
0.517 |
-3.352 |
TANC1 |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
2 |
159533391 |
AB051515 |
85461 |
2q24.2 |
Hs.61590 |
6 |
binding plasma membrane postsynaptic density cell junction synapse postsynaptic membrane |
|
213014_at |
MAPK8IP1 |
mitogen-activated protein kinase 8 interacting protein 1 |
11 |
45863777 |
BG222394 |
9479 |
11p12-p11.2 |
Hs.234249 |
46 |
protein kinase inhibitor activity MAP-kinase scaffold activity protein binding nucleus cytoplasm vesicle-mediated transport kinesin binding protein kinase binding regulation of JNK cascade perinuclear region of cytoplasm |
MAPK signaling pathway |
244296_at |
hCG_1776047 |
hCG1776047 |
18 |
|
T78442 |
727961 |
18q21.2 |
|
1 |
|
|
211332_x_at |
HFE |
hemochromatosis |
6 |
26195487 |
AF144241 |
3077 |
6p21.3 |
Hs.233325 |
592 |
antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome |
|
1567241_at |
OR2L1P |
olfactory receptor, family 2, subfamily L, member 1 pseudogene |
1 |
246220191 |
X64980 |
26247 |
1q44 |
Hs.684887 |
1 |
|
|
1557953_at |
0.279 |
6.391 |
2.260 |
3.892e-02 |
0.567 |
-3.698 |
ZKSCAN1 |
zinc finger with KRAB and SCAN domains 1 |
7 |
99451154 |
BG761185 |
7586 |
7q21.3-q22.1 |
Hs.615360 |
11 |
transcription factor activity intracellular nucleus cytoplasm mitochondrion regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
203648_at |
TATDN2 |
TatD DNase domain containing 2 |
3 |
10265176 |
NM_014760 |
9797 |
3p25.3 |
Hs.475401 Hs.611748 |
5 |
nuclease activity nucleus hydrolase activity endodeoxyribonuclease activity, producing 5'-phosphomonoesters |
|
206694_at |
PNLIPRP1 |
pancreatic lipase-related protein 1 |
10 |
118340479 |
NM_006229 |
5407 |
10q25.3 |
Hs.73923 |
3 |
triacylglycerol lipase activity extracellular region lipid catabolic process hydrolase activity |
Glycerolipid metabolism Metabolic pathways |
223633_s_at |
BCAN |
brevican |
1 |
154878363, 154878363 |
BC005081 |
63827 |
1q31 |
Hs.516904 Hs.663621 |
17 |
binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix cell adhesion membrane anchored to membrane |
|
201024_x_at |
EIF5B |
eukaryotic translation initiation factor 5B |
2 |
99320265 |
BG261322 |
9669 |
2q11.2 |
Hs.158688 |
15 |
nucleotide binding translation initiation factor activity translation initiation factor activity GTPase activity protein binding GTP binding cytoplasm translation regulation of translational initiation regulation of translational initiation |
|
208661_s_at |
TTC3 |
tetratricopeptide repeat domain 3 |
21 |
37367440, 37377116 |
AW510696 |
7267 |
21q22.2 |
Hs.368214 |
9 |
protein binding cellular_component vacuole biological_process zinc ion binding negative regulation of cell morphogenesis involved in differentiation negative regulation of neuron differentiation metal ion binding response to protein stimulus |
|
1552365_at |
-0.399 |
2.789 |
-2.603 |
1.981e-02 |
0.491 |
-3.134 |
SCIN |
scinderin |
7 |
12576727, 12595672 |
NM_033128 |
85477 |
7p21.3 |
Hs.633359 Hs.655515 |
14 |
phosphatidylserine binding calcium ion binding calcium ion binding phosphatidylinositol binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm cytoskeleton cell cortex negative regulation of cell proliferation calcium ion-dependent exocytosis positive regulation of apoptosis actin nucleation positive regulation of megakaryocyte differentiation actin filament severing actin filament binding positive regulation of secretion actin filament capping |
Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
205107_s_at |
EFNA4 |
ephrin-A4 |
1 |
153302836 |
NM_005227 |
1945 |
1q21-q22 |
Hs.449913 Hs.639422 |
23 |
transmembrane-ephrin receptor activity extracellular region plasma membrane integral to plasma membrane cell-cell signaling anchored to membrane |
Axon guidance |
212841_s_at |
PPFIBP2 |
PTPRF interacting protein, binding protein 2 (liprin beta 2) |
11 |
7491576 |
AI692180 |
8495 |
11p15.4 |
Hs.655714 |
8 |
molecular_function DNA binding intracellular cell communication integrase activity DNA integration |
|
208630_at |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit |
2 |
-26267007 |
AI972144 |
3030 |
2p23 |
Hs.516032 |
36 |
acyl-CoA binding 3-hydroxyacyl-CoA dehydrogenase activity acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity enoyl-CoA hydratase activity binding mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation oxidoreductase activity fatty acid beta-oxidation multienzyme complex long-chain-enoyl-CoA hydratase activity long-chain-3-hydroxyacyl-CoA dehydrogenase activity lyase activity response to drug mitochondrial nucleoid NAD or NADH binding oxidation reduction |
Fatty acid elongation in mitochondria Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Tryptophan metabolism beta-Alanine metabolism Benzoate degradation via CoA ligation Propanoate metabolism Butanoate metabolism Limonene and pinene degradation Caprolactam degradation Biosynthesis of unsaturated fatty acids Metabolic pathways |
213511_s_at |
MTMR1 |
myotubularin related protein 1 |
X |
149612526 |
AI167164 |
8776 |
Xq28 |
Hs.347187 |
10 |
protein tyrosine phosphatase activity cellular_component plasma membrane dephosphorylation hydrolase activity phosphatase activity |
Fructose and mannose metabolism Thiamine metabolism Riboflavin metabolism Metabolic pathways |
200640_at |
0.476 |
7.791 |
3.413 |
3.785e-03 |
0.318 |
-1.730 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
8 |
-101999980, -101999980, -101999980, -101999980, -101999980 |
NM_003406 |
7534 |
8q23.1 |
Hs.492407 Hs.594673 |
169 |
nucleus cytoplasm mitochondrion protein targeting anti-apoptosis signal transduction transcription factor binding protein domain specific binding melanosome |
Cell cycle Neurotrophin signaling pathway Pathogenic Escherichia coli infection - EHEC |
1560472_at |
-0.322 |
5.328 |
-3.190 |
6.005e-03 |
0.358 |
-2.123 |
LOC338588 |
hypothetical LOC338588 |
10 |
4688347 |
BC040895 |
338588 |
10p15.1 |
Hs.121365 |
1 |
|
|
203144_s_at |
0.278 |
4.581 |
2.194 |
4.417e-02 |
0.579 |
-3.802 |
KIAA0040 |
KIAA0040 |
1 |
-173392745, -173392745 |
NM_014656 |
9674 |
1q24-q25 |
Hs.518138 |
6 |
|
|
1569003_at |
TMEM49 |
transmembrane protein 49 |
17 |
55139644 |
AL541655 |
81671 |
17q23.1 |
Hs.444569 Hs.708260 |
13 |
endoplasmic reticulum membrane integral to membrane |
|
230956_at |
C11orf92 |
chromosome 11 open reading frame 92 |
11 |
-110669379 |
AI347581 |
399948 |
11q23.1 |
Hs.125166 |
1 |
membrane integral to membrane |
|
235160_at |
ATF7 |
activating transcription factor 7 |
12 |
-52192109, -52192109 |
BG105181 |
11016 |
12q13 |
Hs.12286 |
18 |
transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding protein dimerization activity |
|
225733_at |
0.252 |
5.786 |
2.496 |
2.449e-02 |
0.513 |
-3.312 |
B3GALT6 |
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 |
1 |
1157491 |
AI890557 |
126792 |
1p36.33 |
Hs.284284 |
4 |
Golgi apparatus Golgi medial cisterna glycosaminoglycan biosynthetic process protein amino acid glycosylation UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding galactosylxylosylprotein 3-beta-galactosyltransferase activity |
Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways |
215016_x_at |
DST |
dystonin |
6 |
-56587338, -56576527, -56430743, -56430743, -56430743, -56430743, -56430743 |
BC004912 |
667 |
6p12.1 |
Hs.631992 Hs.669931 |
48 |
actin binding integrin binding calcium ion binding protein binding protein binding basement membrane cytoplasm cytoplasm cytoskeleton cell cycle arrest cell adhesion integrin-mediated signaling pathway protein C-terminus binding cytoplasmic membrane-bounded vesicle actin cytoskeleton organization hemidesmosome intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization actin filament binding |
|
224376_s_at |
C20orf24 |
chromosome 20 open reading frame 24 |
20 |
34667580, 34667605 |
AF274948 |
55969 |
20q11.23 |
Hs.584985 |
7 |
molecular_function protein binding cellular_component biological_process |
|
208242_at |
RAX |
retina and anterior neural fold homeobox |
18 |
-55085246 |
NM_013435 |
30062 |
18q21.32 |
Hs.278957 |
8 |
transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development visual perception sequence-specific DNA binding |
|
231734_at |
RBP2 |
retinol binding protein 2, cellular |
3 |
-140654415 |
NM_004164 |
5948 |
3q23 |
Hs.655516 |
14 |
transporter activity cytoplasm vitamin A metabolic process transport lipid binding epidermis development retinal binding retinol binding |
|
241580_at |
ZNF518B |
zinc finger protein 518B |
4 |
-10050601 |
AI375526 |
85460 |
4p16.1 |
Hs.455089 |
3 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
226287_at |
CCDC34 |
coiled-coil domain containing 34 |
11 |
-27326994, -27316636 |
AI458313 |
91057 |
11p14.1 |
Hs.143733 |
4 |
|
|
217957_at |
C16orf80 |
chromosome 16 open reading frame 80 |
16 |
-56704997 |
NM_013242 |
29105 |
16q21 |
Hs.532755 |
3 |
multicellular organismal development |
|
210006_at |
ABHD14A |
abhydrolase domain containing 14A |
3 |
51984081 |
BC002571 |
25864 |
3p21.1 |
Hs.534400 |
6 |
cytoplasm membrane integral to membrane hydrolase activity |
|
224747_at |
UBE2Q2 |
ubiquitin-conjugating enzyme E2Q family member 2 |
15 |
73922676, 73923439 |
AK000617 |
92912 |
15q24.2 |
Hs.23033 |
4 |
nucleotide binding ubiquitin-protein ligase activity ATP binding cytoplasm ligase activity modification-dependent protein catabolic process post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
210072_at |
-0.254 |
3.942 |
-2.712 |
1.592e-02 |
0.459 |
-2.950 |
CCL19 |
chemokine (C-C motif) ligand 19 |
9 |
-34679566 |
U88321 |
6363 |
9p13 |
Hs.50002 |
39 |
extracellular region extracellular space cellular calcium ion homeostasis chemotaxis inflammatory response immune response signal transduction chemokine activity response to virus |
Cytokine-cytokine receptor interaction Chemokine signaling pathway |
205442_at |
MFAP3L |
microfibrillar-associated protein 3-like |
4 |
-171144322, -171144322 |
NM_021647 |
9848 |
4q32.3 |
Hs.593942 |
3 |
plasma membrane integral to membrane |
|
202495_at |
TBCC |
tubulin folding cofactor C |
6 |
-42820211 |
NM_003192 |
6903 |
6pter-p12.1 |
Hs.75064 |
6 |
binding cytoskeleton microtubule post-chaperonin tubulin folding pathway chaperone binding |
|
212327_at |
LIMCH1 |
LIM and calponin homology domains 1 |
4 |
41057560, 41309675 |
AK026815 |
22998 |
4p13 |
Hs.335163 |
10 |
actin binding zinc ion binding actomyosin structure organization metal ion binding |
|
205319_at |
PSCA |
prostate stem cell antigen |
8 |
143758876 |
NM_005672 |
8000 |
8q24.2 |
Hs.652235 Hs.711174 |
31 |
plasma membrane anchored to membrane |
|
208173_at |
IFNB1 |
interferon, beta 1, fibroblast |
9 |
-21067103 |
NM_002176 |
3456 |
9p21 |
Hs.93177 |
127 |
transcription corepressor activity cytokine activity interferon-alpha/beta receptor binding extracellular region extracellular space induction of apoptosis activation of caspase activity activation of caspase activity cell surface receptor linked signal transduction negative regulation of cell proliferation response to virus natural killer cell activation negative regulation of viral transcription B cell proliferation defense response to bacterium positive regulation of innate immune response regulation of MHC class I biosynthetic process negative regulation of virion penetration into host cell |
Cytokine-cytokine receptor interaction Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity |
1555748_x_at |
CD79B |
CD79b molecule, immunoglobulin-associated beta |
17 |
-59359829 |
BC030210 |
974 |
17q23 |
Hs.89575 |
45 |
transmembrane receptor activity nucleus cytoplasm Golgi apparatus plasma membrane integral to plasma membrane immune response cell surface receptor linked signal transduction |
B cell receptor signaling pathway |
201797_s_at |
VARS |
valyl-tRNA synthetase |
6 |
-31853275, -3191374, -3006978 |
NM_006295 |
7407 |
6p21.3 |
Hs.520026 |
15 |
nucleotide binding valine-tRNA ligase activity protein binding ATP binding intracellular cytoplasm mitochondrion cytosol translational elongation valyl-tRNA aminoacylation defense response response to unfolded protein response to nutrient ligase activity protein complex NF-kappaB binding |
Valine, leucine and isoleucine biosynthesis Aminoacyl-tRNA biosynthesis |
202393_s_at |
-0.663 |
9.258 |
-2.370 |
3.139e-02 |
0.543 |
-3.519 |
KLF10 |
Kruppel-like factor 10 |
8 |
-103730182, -103730182 |
NM_005655 |
7071 |
8q22.2 |
Hs.435001 |
26 |
negative regulation of transcription from RNA polymerase II promoter skeletal system development transcription factor activity protein binding intracellular nucleus transforming growth factor beta receptor signaling pathway cell-cell signaling zinc ion binding negative regulation of cell proliferation regulation of transcription metal ion binding |
|
1554057_at |
LOC645676 |
hypothetical LOC645676 |
1 |
153798395 |
BC017347 |
645676 |
1q22 |
Hs.491060 Hs.568693 |
1 |
|
|
205650_s_at |
FGA |
fibrinogen alpha chain |
4 |
-155725878, -155723729 |
NM_021871 |
2243 |
4q28 |
Hs.351593 |
180 |
receptor binding extracellular region extracellular region fibrinogen complex plasma membrane signal transduction external side of plasma membrane platelet activation protein binding, bridging platelet alpha granule lumen tissue regeneration eukaryotic cell surface binding protein polymerization response to calcium ion |
Complement and coagulation cascades |
241759_at |
MGC5566 |
hypothetical protein MGC5566 |
20 |
|
T82487 |
79015 |
20q13.12 |
Hs.255479 |
1 |
|
|
204831_at |
CDK8 |
cyclin-dependent kinase 8 |
13 |
25726755 |
R59697 |
1024 |
13q12 |
Hs.382306 |
38 |
nucleotide binding cyclin-dependent protein kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation RNA polymerase II carboxy-terminal domain kinase activity transferase activity regulation of transcription |
|
208198_x_at |
KIR2DS1 |
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
19 |
257787 |
NM_014512 |
3806 |
19q13.4 |
Hs.512572 |
57 |
transmembrane receptor activity plasma membrane immune response integral to membrane |
Antigen processing and presentation Natural killer cell mediated cytotoxicity |
222539_at |
CLN6 |
ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
15 |
-66286385 |
NM_017882 |
54982 |
15q23 |
Hs.584921 |
21 |
ganglioside metabolic process endoplasmic reticulum endoplasmic reticulum lumen lysosomal lumen acidification visual perception cholesterol metabolic process membrane integral to membrane protein catabolic process glycosaminoglycan metabolic process locomotion involved in locomotory behavior protein homodimerization activity cellular macromolecule catabolic process positive regulation of proteolysis |
|
221015_s_at |
CDADC1 |
cytidine and dCMP deaminase domain containing 1 |
13 |
48720103 |
NM_030911 |
81602 |
13q14.2 |
Hs.388220 |
2 |
zinc ion binding hydrolase activity metal ion binding |
|
211663_x_at |
PTGDS |
prostaglandin D2 synthase 21kDa (brain) |
9 |
138991776 |
M61900 |
5730 |
9q34.2-q34.3 |
Hs.446429 |
63 |
prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm |
Arachidonic acid metabolism Metabolic pathways |
232370_at |
-0.240 |
5.759 |
-2.156 |
4.745e-02 |
0.585 |
-3.861 |
LOC254057 |
hypothetical protein LOC254057 |
3 |
|
AI635756 |
254057 |
3q21.3 |
Hs.586109 |
|
|
|
229530_at |
GUCY1A3 |
guanylate cyclase 1, soluble, alpha 3 |
4 |
156807311, 156807311, 156807311, 156807598, 156807598, 156808264 |
BF002625 |
2982 |
4q31.1-q31.2 4q31.3-q33 |
Hs.24258 |
14 |
nucleotide binding guanylate cyclase activity receptor activity GTP binding cytoplasm nitric oxide mediated signal transduction guanylate cyclase complex, soluble regulation of blood pressure positive regulation of cGMP biosynthetic process response to defense-related host nitric oxide production relaxation of vascular smooth muscle |
Purine metabolism Vascular smooth muscle contraction Gap junction Long-term depression |
231887_s_at |
KIAA1274 |
KIAA1274 |
10 |
71908569 |
AB033100 |
27143 |
10q22.1 |
Hs.202351 |
5 |
|
|
213274_s_at |
CTSB |
cathepsin B |
8 |
-11737442 |
AA020826 |
1508 |
8p22 |
Hs.520898 |
140 |
cysteine-type endopeptidase activity extracellular region intracellular soluble fraction mitochondrion lysosome proteolysis peptidase activity response to wounding external side of plasma membrane apical plasma membrane kininogen binding peptide binding melanosome regulation of apoptosis regulation of catalytic activity |
Lysosome Antigen processing and presentation |
233030_at |
0.635 |
4.430 |
2.269 |
3.826e-02 |
0.565 |
-3.684 |
PNPLA3 |
patatin-like phospholipase domain containing 3 |
22 |
42650951 |
AK025665 |
80339 |
22q13.31 |
Hs.654800 |
20 |
phospholipase A2 activity triacylglycerol lipase activity metabolic process acyltransferase activity membrane integral to membrane lipid catabolic process transferase activity hydrolase activity triglyceride biosynthetic process triglyceride catabolic process mono-olein transacylation activity diolein transacylation activity |
Tyrosine metabolism Phenylalanine metabolism Glycerolipid metabolism Glycerophospholipid metabolism 1- and 2-Methylnaphthalene degradation Benzoate degradation via CoA ligation Limonene and pinene degradation Metabolic pathways |
223048_at |
0.305 |
7.411 |
2.576 |
2.092e-02 |
0.497 |
-3.180 |
SDHAF2 |
succinate dehydrogenase complex assembly factor 2 |
11 |
60954172 |
BC002331 |
54949 |
11q12.2 |
Hs.313247 |
3 |
molecular_function cellular_component mitochondrion biological_process |
|
237300_at |
PSMA3 |
proteasome (prosome, macropain) subunit, alpha type, 3 |
14 |
57781345 |
AI553756 |
5684 |
14q23 |
Hs.558799 |
58 |
threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex cytoskeleton ubiquitin-dependent protein catabolic process peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
1561571_at |
-0.254 |
5.427 |
-2.946 |
9.886e-03 |
0.412 |
-2.546 |
LOC730139 |
hypothetical protein LOC730139 |
3 |
|
BC028116 |
730139 |
3q27.3 |
Hs.679195 |
1 |
|
|
230863_at |
LRP2 |
low density lipoprotein-related protein 2 |
2 |
-169691864 |
R73030 |
4036 |
2q24-q31 |
Hs.657729 |
65 |
receptor activity calcium ion binding protein binding membrane fraction lysosome endosome endoplasmic reticulum Golgi apparatus brush border coated pit protein amino acid glycosylation lipid metabolic process vitamin metabolic process receptor-mediated endocytosis cell proliferation membrane integral to membrane apical plasma membrane SH3 domain binding endocytic vesicle forebrain development |
Hedgehog signaling pathway |
38269_at |
PRKD2 |
protein kinase D2 |
19 |
-51869412, -51869412 |
AL050147 |
25865 |
19q13.3 |
Hs.466987 |
25 |
nucleotide binding protein kinase C activity ATP binding intracellular protein amino acid phosphorylation intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding metal ion binding |
|
218041_x_at |
0.640 |
9.513 |
2.147 |
4.833e-02 |
0.589 |
-3.876 |
SLC38A2 |
solute carrier family 38, member 2 |
12 |
-45038238 |
NM_018573 |
54407 |
12q |
Hs.221847 |
20 |
plasma membrane ion transport sodium ion transport amino acid transport symporter activity integral to membrane sodium ion binding |
|
215883_at |
CTNNA1 |
catenin (cadherin-associated protein), alpha 1, 102kDa |
5 |
138117005 |
AK022326 |
1495 |
5q31 |
Hs.534797 Hs.656653 |
70 |
structural molecule activity protein binding cytoplasm plasma membrane adherens junction cell adhesion actin cytoskeleton vinculin binding cell junction apical junction assembly cadherin binding |
Adherens junction Tight junction Leukocyte transendothelial migration Pathways in cancer Endometrial cancer Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
208423_s_at |
-0.244 |
3.095 |
-2.482 |
2.520e-02 |
0.514 |
-3.336 |
MSR1 |
macrophage scavenger receptor 1 |
8 |
-16041196, -16009757 |
NM_002445 |
4481 |
8p22 |
Hs.147635 |
51 |
receptor activity scavenger receptor activity protein binding integral to plasma membrane receptor-mediated endocytosis positive regulation of foam cell differentiation positive regulation of cholesterol storage membrane low-density lipoprotein binding cholesterol transport low-density lipoprotein particle lipoprotein particle clearance |
|
202819_s_at |
TCEB3 |
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) |
1 |
23942442 |
NM_003198 |
6924 |
1p36.1 |
Hs.15535 |
26 |
DNA binding protein binding nucleus nucleoplasm cytoplasm regulation of transcription from RNA polymerase II promoter integral to membrane transcription regulator activity regulation of transcription |
|
204620_s_at |
0.810 |
5.836 |
3.703 |
2.082e-03 |
0.275 |
-1.221 |
VCAN |
versican |
5 |
82803248 |
NM_004385 |
1462 |
5q14.3 |
Hs.643801 Hs.715773 |
74 |
binding calcium ion binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix cell adhesion multicellular organismal development cell recognition |
Cell adhesion molecules (CAMs) |
227111_at |
-0.483 |
5.341 |
-3.872 |
1.471e-03 |
0.250 |
-0.926 |
ZBTB34 |
zinc finger and BTB domain containing 34 |
9 |
128662764 |
BG179317 |
403341 |
9q33.3 |
Hs.177633 |
4 |
DNA binding protein binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
204697_s_at |
CHGA |
chromogranin A (parathyroid secretory protein 1) |
14 |
92459197 |
NM_001275 |
1113 |
14q32 |
Hs.150793 |
96 |
calcium ion binding extracellular region regulation of blood pressure |
|
212958_x_at |
0.462 |
9.545 |
2.621 |
1.910e-02 |
0.489 |
-3.103 |
PAM |
peptidylglycine alpha-amidating monooxygenase |
5 |
102229425 |
AI022882 |
5066 |
5q14-q21 |
Hs.369430 |
34 |
monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding protein binding extracellular region protein modification process peptide metabolic process zinc ion binding cellular process membrane integral to membrane lyase activity secretory granule L-ascorbic acid binding metal ion binding oxidation reduction |
|
215420_at |
-0.254 |
5.463 |
-2.344 |
3.308e-02 |
0.551 |
-3.563 |
IHH |
Indian hedgehog homolog (Drosophila) |
2 |
-219627389 |
BE869172 |
3549 |
2q33-q35 |
Hs.654504 |
41 |
skeletal system development patterning of blood vessels osteoblast differentiation patched binding protein binding extracellular region extracellular space plasma membrane proteolysis cell-cell signaling pattern specification process peptidase activity negative regulation of signal transduction cholesterol binding intein-mediated protein splicing positive regulation of chondrocyte differentiation negative regulation of apoptosis negative regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter cell maturation positive regulation of epithelial cell proliferation |
Hedgehog signaling pathway |
226318_at |
TBRG1 |
transforming growth factor beta regulator 1 |
11 |
123997951 |
AI701055 |
84897 |
11q24.2 |
Hs.436410 |
11 |
DNA binding protein binding nucleus DNA replication cell cycle cell cycle arrest negative regulation of cell proliferation nucleolus to nucleoplasm transport protein stabilization |
|
212251_at |
MTDH |
metadherin |
8 |
98725582 |
AI972475 |
92140 |
8q22.1 |
Hs.377155 |
23 |
negative regulation of transcription from RNA polymerase II promoter protein binding nucleus nucleolus cytoplasm endoplasmic reticulum tight junction membrane integral to membrane cell junction nuclear membrane perinuclear region of cytoplasm NF-kappaB binding positive regulation of NF-kappaB transcription factor activity |
|
201315_x_at |
IFITM2 |
interferon induced transmembrane protein 2 (1-8D) |
11 |
298106 |
NM_006435 |
10581 |
11p15.5 |
Hs.709321 |
6 |
protein binding immune response response to biotic stimulus membrane integral to membrane |
|
201672_s_at |
USP14 |
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
18 |
148482 |
NM_005151 |
9097 |
18p11.32 |
Hs.464416 Hs.707058 |
15 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity cytoplasm ubiquitin-dependent protein catabolic process tRNA guanylyltransferase activity peptidase activity |
|
206207_at |
CLC |
Charcot-Leyden crystal protein |
19 |
-44913734 |
NM_001828 |
1178 |
19q13.1 |
Hs.889 |
25 |
lysophospholipase activity sugar binding multicellular organismal development lipid catabolic process hydrolase activity |
|
238014_at |
TMEM194B |
transmembrane protein 194B |
2 |
-191079864 |
AW291339 |
100131211 |
2q32.2 |
Hs.659824 |
2 |
membrane integral to membrane |
|
209089_at |
0.293 |
9.034 |
2.669 |
1.737e-02 |
0.471 |
-3.023 |
RAB5A |
RAB5A, member RAS oncogene family |
3 |
19963575 |
BC001267 |
5868 |
3p24-p22 |
Hs.475663 |
73 |
nucleotide binding ruffle GTPase activity protein binding protein binding GTP binding early endosome plasma membrane endocytosis small GTPase mediated signal transduction protein transport guanyl nucleotide binding endocytic vesicle melanosome membrane raft |
Endocytosis Amyotrophic lateral sclerosis (ALS) |
230323_s_at |
TMEM45B |
transmembrane protein 45B |
11 |
129190950 |
AW242836 |
120224 |
11q24.3 |
Hs.504301 |
3 |
membrane integral to membrane |
|
218456_at |
CAPRIN2 |
caprin family member 2 |
12 |
-30753752 |
NM_023925 |
65981 |
12p11 |
Hs.234355 |
7 |
cytoplasm mitochondrion negative regulation of cell growth regulation of growth |
|
217365_at |
-0.271 |
4.164 |
-2.828 |
1.259e-02 |
0.429 |
-2.752 |
PRAMEF11 |
PRAME family member 11 |
1 |
-12807054 |
AL022101 |
440560 |
1p36.21 |
Hs.551617 |
2 |
|
|
218565_at |
0.405 |
4.995 |
3.306 |
4.728e-03 |
0.337 |
-1.919 |
C9orf114 |
chromosome 9 open reading frame 114 |
9 |
-130624165 |
BG223334 |
51490 |
9q34.11 |
Hs.224137 |
5 |
molecular_function cellular_component biological_process |
|
223460_at |
CAMKK1 |
calcium/calmodulin-dependent protein kinase kinase 1, alpha |
17 |
-3715199, -3710365, -3710365 |
AL136576 |
84254 |
17p13.2 |
Hs.8417 |
16 |
nucleotide binding calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm protein amino acid phosphorylation transferase activity |
Adipocytokine signaling pathway |
213749_at |
MASP1 |
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
3 |
-188447299, -188434565, -188418631 |
AV686235 |
5648 |
3q27-q28 |
Hs.89983 |
30 |
complement activation, lectin pathway complement activation, lectin pathway serine-type endopeptidase activity calcium ion binding extracellular region extracellular region extracellular space proteolysis peptidase activity protein homodimerization activity calcium-dependent protein binding |
Complement and coagulation cascades |
215368_at |
NEB |
nebulin |
2 |
-152050098 |
R78299 |
4703 |
2q22 |
Hs.588655 |
32 |
actin binding protein binding cytoplasm somatic muscle development structural constituent of muscle actin cytoskeleton sarcomere Z disc regulation of actin filament length |
|
216342_x_at |
-0.272 |
11.005 |
-2.169 |
4.635e-02 |
0.582 |
-3.842 |
RPS4X |
ribosomal protein S4, X-linked |
X |
-71409177 |
AL121916 |
6191 |
Xq13.1 |
Hs.118076 |
25 |
structural constituent of ribosome intracellular cytosol ribosome polysome translational elongation multicellular organismal development positive regulation of cell proliferation rRNA binding cytosolic small ribosomal subunit cytosolic small ribosomal subunit positive regulation of translation |
Ribosome |
231045_x_at |
C11orf31 |
chromosome 11 open reading frame 31 |
11 |
57265297 |
H29876 |
280636 |
11q12.1 |
Hs.655373 Hs.719147 |
6 |
selenium binding cell redox homeostasis |
|
205813_s_at |
-0.262 |
5.284 |
-2.440 |
2.736e-02 |
0.526 |
-3.405 |
MAT1A |
methionine adenosyltransferase I, alpha |
10 |
-82021555 |
NM_000429 |
4143 |
10q22 |
Hs.282670 |
21 |
nucleotide binding magnesium ion binding methionine adenosyltransferase activity ATP binding cellular amino acid metabolic process one-carbon metabolic process transferase activity potassium ion binding cobalt ion binding |
Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways |
226924_at |
LOC400657 |
hypothetical LOC400657 |
18 |
-70409991 |
AI016355 |
400657 |
18q22.3 |
Hs.61508 |
3 |
|
|
211203_s_at |
CNTN1 |
contactin 1 |
12 |
39372624 |
U07820 |
1272 |
12q11-q12 |
Hs.143434 |
30 |
protein binding membrane fraction plasma membrane cell adhesion Notch signaling pathway anchored to membrane |
Cell adhesion molecules (CAMs) |
219157_at |
KLHL2 |
kelch-like 2, Mayven (Drosophila) |
4 |
166348219, 166350620 |
NM_007246 |
11275 |
4q21.2 |
Hs.388668 |
7 |
actin binding transporter activity protein binding cytoplasm intracellular protein transport actin cytoskeleton |
|
239629_at |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
AI634046 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
1569246_a_at |
-0.366 |
5.127 |
-3.083 |
7.474e-03 |
0.376 |
-2.309 |
C8orf74 |
chromosome 8 open reading frame 74 |
8 |
10567556 |
BC038534 |
203076 |
8p23.1 |
Hs.371776 |
2 |
|
|
60084_at |
0.307 |
3.429 |
2.412 |
2.895e-02 |
0.534 |
-3.452 |
CYLD |
cylindromatosis (turban tumor syndrome) |
16 |
49333461, 49333529 |
AI453099 |
1540 |
16q12.1 |
Hs.578973 |
54 |
structural constituent of ribosome ubiquitin thiolesterase activity intracellular cytoplasm ribosome cytoskeleton translation ubiquitin-dependent protein catabolic process cell cycle peptidase activity cysteine-type peptidase activity perinuclear region of cytoplasm |
RIG-I-like receptor signaling pathway |
224498_x_at |
AXIN2 |
axin 2 |
17 |
-60955146 |
BC006295 |
8313 |
17q23-q24 |
Hs.156527 |
38 |
somitogenesis intramembranous ossification signal transducer activity protein binding intracellular nucleus cytoplasm signal transduction multicellular organismal development negative regulation of cell proliferation regulation of Wnt receptor signaling pathway negative regulation of osteoblast differentiation |
Wnt signaling pathway Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma |
203213_at |
0.489 |
3.318 |
2.559 |
2.162e-02 |
0.497 |
-3.207 |
CDC2 |
cell division cycle 2, G1 to S and G2 to M |
10 |
62208225, 62208296, 62209904 |
AL524035 |
983 |
10q21.1 |
Hs.334562 |
350 |
nucleotide binding cyclin-dependent protein kinase activity cyclin-dependent protein kinase activity protein binding ATP binding nucleus nucleoplasm cytosol spindle microtubule protein amino acid phosphorylation anti-apoptosis cell cycle mitosis RNA polymerase II carboxy-terminal domain kinase activity transferase activity midbody anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle p53 signaling pathway Gap junction |
1564251_at |
-0.257 |
5.359 |
-2.326 |
3.423e-02 |
0.553 |
-3.591 |
EMID1 |
EMI domain containing 1 |
22 |
27931952 |
AL831910 |
129080 |
22q12.2 |
Hs.289106 |
5 |
protein binding extracellular region proteinaceous extracellular matrix endoplasmic reticulum Golgi apparatus |
|
206611_at |
-0.304 |
6.200 |
-2.428 |
2.802e-02 |
0.529 |
-3.425 |
C2orf27A |
chromosome 2 open reading frame 27A |
2 |
132196533 |
NM_013310 |
29798 |
2q21.1-q21.2 |
Hs.635289 Hs.655680 |
5 |
|
|
227536_at |
-0.399 |
7.368 |
-2.787 |
1.367e-02 |
0.440 |
-2.821 |
ZC3H13 |
zinc finger CCCH-type containing 13 |
13 |
-45434314 |
AI472196 |
23091 |
13q14.13 |
Hs.136102 |
11 |
nucleic acid binding zinc ion binding metal ion binding |
|
239027_at |
DOCK8 |
dedicator of cytokinesis 8 |
9 |
204864 |
AV760561 |
81704 |
9p24.3 |
Hs.132599 |
11 |
guanyl-nucleotide exchange factor activity GTP binding GTPase binding |
|
212714_at |
LARP4 |
La ribonucleoprotein domain family, member 4 |
12 |
49080916 |
AL050205 |
113251 |
12q13.12 |
Hs.26613 |
7 |
RNA binding |
|
202351_at |
ITGAV |
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) |
2 |
187163034, 187173176 |
AI093579 |
3685 |
2q31-q32 |
Hs.436873 |
240 |
blood vessel development receptor activity calcium ion binding protein binding plasma membrane cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex external side of plasma membrane negative regulation of foam cell differentiation negative regulation of lipid storage negative regulation of lipid transport apoptotic cell clearance interspecies interaction between organisms negative regulation of low-density lipoprotein receptor biosynthetic process negative regulation of lipoprotein metabolic process |
Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
223041_at |
CD99L2 |
CD99 molecule-like 2 |
X |
-149685466 |
AL136580 |
83692 |
Xq28 |
Hs.522805 |
8 |
protein binding plasma membrane cell adhesion integral to membrane cell junction |
|
213049_at |
GARNL1 |
GTPase activating Rap/RanGAP domain-like 1 |
14 |
-35077308 |
BG436400 |
253959 |
14q13.2 |
Hs.113150 |
10 |
GTPase activator activity intracellular nucleus cytoplasm mitochondrion regulation of small GTPase mediated signal transduction |
|
204937_s_at |
0.458 |
6.340 |
2.299 |
3.607e-02 |
0.558 |
-3.635 |
ZNF274 |
zinc finger protein 274 |
19 |
63386207 |
NM_016325 |
10782 |
19qter |
Hs.658497 Hs.83761 |
11 |
transcription factor activity transcription corepressor activity protein binding intracellular nucleus nucleolus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
Neurotrophin signaling pathway |
225481_at |
FRMD6 |
FERM domain containing 6 |
14 |
51025604, 51188325 |
AL040051 |
122786 |
14q22.1 |
Hs.434914 |
9 |
binding cytoplasm mitochondrion cytoskeleton plasma membrane |
|
203441_s_at |
CDH2 |
cadherin 2, type 1, N-cadherin (neuronal) |
18 |
-23784927 |
NM_001792 |
1000 |
18q11.2 |
Hs.464829 Hs.606106 |
102 |
calcium ion binding plasma membrane adherens junction cell adhesion homophilic cell adhesion heterophilic cell adhesion synaptogenesis integral to membrane calcium-dependent cell-cell adhesion cell migration protein phosphatase binding lamellipodium RPTP-like protein binding synapse blood vessel morphogenesis |
Cell adhesion molecules (CAMs) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
205856_at |
SLC14A1 |
solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
18 |
41558089, 41560915 |
NM_015865 |
6563 |
18q11-q12 |
Hs.101307 |
27 |
plasma membrane integral to plasma membrane transport urea transmembrane transporter activity urea transport ubiquitin-ubiquitin ligase activity |
|
206857_s_at |
0.436 |
4.192 |
3.013 |
8.622e-03 |
0.391 |
-2.430 |
FKBP1B |
FK506 binding protein 1B, 12.6 kDa |
2 |
24126087 |
NM_004116 |
2281 |
2p23.3 |
Hs.709461 |
26 |
peptidyl-prolyl cis-trans isomerase activity receptor binding ryanodine-sensitive calcium-release channel activity FK506 binding cytoplasm cytosol 'de novo' protein folding muscle contraction negative regulation of heart rate regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion isomerase activity protein maturation by protein folding regulation of calcium ion transport via store-operated calcium channel activity negative regulation of protein phosphatase type 2B activity calcium channel complex protein refolding response to redox state regulation of ryanodine-sensitive calcium-release channel activity regulation of ryanodine-sensitive calcium-release channel activity |
|
219107_at |
BCAN |
brevican |
1 |
154878363, 154878363 |
NM_021948 |
63827 |
1q31 |
Hs.516904 Hs.663621 |
17 |
binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix cell adhesion membrane anchored to membrane |
|
204863_s_at |
IL6ST |
interleukin 6 signal transducer (gp130, oncostatin M receptor) |
5 |
-55272450 |
BE856546 |
3572 |
5q11 |
Hs.532082 |
124 |
positive regulation of acute inflammatory response positive regulation of adaptive immune response receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity interleukin-6 receptor activity interleukin-11 receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity receptor binding ciliary neurotrophic factor receptor binding extracellular region plasma membrane interleukin-6 receptor complex oncostatin-M receptor complex glycogen metabolic process signal transduction positive regulation of cell proliferation regulation of Notch signaling pathway external side of plasma membrane positive regulation vascular endothelial growth factor production positive regulation of cardiac muscle hypertrophy integral to membrane response to cytokine stimulus positive regulation of T cell proliferation positive regulation of tyrosine phosphorylation of Stat1 protein positive regulation of tyrosine phosphorylation of Stat3 protein protein homodimerization activity interleukin-27 receptor activity positive regulation of osteoblast differentiation positive regulation of anti-apoptosis leukemia inhibitory factor signaling pathway interleukin-27-mediated signaling pathway ciliary neurotrophic factor receptor complex ciliary neurotrophic factor-mediated signaling pathway |
Cytokine-cytokine receptor interaction Jak-STAT signaling pathway |
241869_at |
APOL6 |
apolipoprotein L, 6 |
22 |
34374369 |
AW026509 |
80830 |
22q12.3 |
Hs.257352 |
12 |
lipid transporter activity extracellular region cytoplasm lipid transport lipid binding lipoprotein metabolic process |
|
223012_at |
0.508 |
8.695 |
2.659 |
1.769e-02 |
0.473 |
-3.039 |
UBXN6 |
UBX domain protein 6 |
19 |
-4396260 |
AF272894 |
80700 |
19p13 |
Hs.435255 Hs.661664 |
6 |
molecular_function protein binding cellular_component nucleus cytoplasm centrosome biological_process modification-dependent protein catabolic process |
|
217800_s_at |
NDFIP1 |
Nedd4 family interacting protein 1 |
5 |
141468507 |
NM_030571 |
80762 |
5q31.3 |
Hs.653510 Hs.9788 |
11 |
signal transducer activity protein binding Golgi apparatus cellular iron ion homeostasis negative regulation of gene expression membrane integral to membrane positive regulation of protein ubiquitination negative regulation of transporter activity positive regulation of I-kappaB kinase/NF-kappaB cascade perinuclear region of cytoplasm negative regulation of protein transport |
|
205788_s_at |
ZC3H11A |
zinc finger CCCH-type containing 11A |
1 |
202031373 |
NM_014827 |
9877 |
1q32.1 |
Hs.532399 |
13 |
nucleic acid binding protein binding zinc ion binding metal ion binding |
|
205727_at |
TEP1 |
telomerase-associated protein 1 |
14 |
-19903666 |
NM_007110 |
7011 |
14q11.2 |
Hs.508835 |
19 |
nucleotide binding telomere maintenance via recombination chromosome, telomeric region telomerase activity RNA binding ATP binding soluble fraction nucleus chromosome telomerase holoenzyme complex cytoplasm nuclear matrix |
|
203877_at |
MMP11 |
matrix metallopeptidase 11 (stromelysin 3) |
22 |
22445035 |
NM_005940 |
4320 |
22q11.2 22q11.23 |
Hs.143751 |
30 |
metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix proteolysis multicellular organismal development peptidase activity zinc ion binding collagen catabolic process |
|
225056_at |
-1.110 |
6.453 |
-4.211 |
7.351e-04 |
0.211 |
-0.341 |
SIPA1L2 |
signal-induced proliferation-associated 1 like 2 |
1 |
-230600334 |
AB037810 |
57568 |
1q42.2 |
Hs.715656 |
8 |
GTPase activator activity protein binding intracellular regulation of small GTPase mediated signal transduction |
|
237388_at |
GLMN |
glomulin, FKBP associated protein |
1 |
-92484542 |
BF224204 |
11146 |
1p22.1 |
Hs.49105 |
14 |
vasculogenesis hepatocyte growth factor receptor binding protein binding protein binding intracellular regulation of gene expression, epigenetic negative regulation of T cell proliferation positive regulation of phosphorylation muscle cell differentiation positive regulation of interleukin-2 biosynthetic process positive regulation of cytokine secretion |
|
202866_at |
0.245 |
7.302 |
2.223 |
4.174e-02 |
0.574 |
-3.755 |
DNAJB12 |
DnaJ (Hsp40) homolog, subfamily B, member 12 |
10 |
-73762593 |
BG283782 |
54788 |
10q22.1 |
Hs.696014 |
7 |
endoplasmic reticulum protein folding membrane integral to membrane heat shock protein binding unfolded protein binding |
|
203983_at |
TSNAX |
translin-associated factor X |
1 |
229731021 |
NM_005999 |
7257 |
1q42.1 |
Hs.96247 |
17 |
nucleus cytoplasm multicellular organismal development spermatogenesis protein transporter activity cell differentiation sequence-specific DNA binding perinuclear region of cytoplasm |
|
1559646_a_at |
NCRNA00184 |
non-protein coding RNA 184 |
1 |
|
AJ421679 |
100302691 |
1q42.3 |
Hs.209162 |
|
|
|
203573_s_at |
RABGGTA |
Rab geranylgeranyltransferase, alpha subunit |
14 |
-23804583, -23804583 |
NM_004581 |
5875 |
14q11.2 |
Hs.377992 |
14 |
Rab geranylgeranyltransferase activity protein binding protein modification process visual perception zinc ion binding protein prenyltransferase activity transferase activity protein geranylgeranylation protein amino acid prenylation metal ion binding |
|
225044_at |
0.357 |
7.299 |
2.758 |
1.450e-02 |
0.447 |
-2.871 |
NT5C3L |
5'-nucleotidase, cytosolic III-like |
17 |
-37234948 |
AL526783 |
115024 |
17q21.2 |
Hs.237536 |
1 |
nucleotide binding magnesium ion binding cytoplasm 5'-nucleotidase activity nucleotide metabolic process transferase activity hydrolase activity |
|
239247_at |
LOC401577 |
hypothetical protein LOC401577 |
X, Y |
|
AI972146 |
401577 |
Xp22.33 Yp11.31 |
Hs.444541 |
2 |
|
|
227462_at |
1.639 |
5.640 |
2.419 |
2.856e-02 |
0.532 |
-3.441 |
ERAP2 |
endoplasmic reticulum aminopeptidase 2 |
5 |
96237399 |
BE889628 |
64167 |
5q15 |
Hs.482910 |
14 |
aminopeptidase activity endoplasmic reticulum endoplasmic reticulum lumen proteolysis immune response regulation of blood pressure peptidase activity metallopeptidase activity zinc ion binding membrane integral to membrane antigen processing and presentation of endogenous peptide antigen via MHC class I metal ion binding |
|
208274_at |
-0.250 |
4.639 |
-2.364 |
3.176e-02 |
0.544 |
-3.529 |
OCLM |
oculomedin |
1 |
184636326 |
NM_022375 |
10896 |
1q25 |
Hs.679230 |
6 |
visual perception |
|
233587_s_at |
-1.041 |
5.782 |
-4.798 |
2.261e-04 |
0.172 |
0.642 |
SIPA1L2 |
signal-induced proliferation-associated 1 like 2 |
1 |
-230600334 |
AK022852 |
57568 |
1q42.2 |
Hs.715656 |
8 |
GTPase activator activity protein binding intracellular regulation of small GTPase mediated signal transduction |
|
228593_at |
MTMR9L |
myotubularin related protein 9-like |
1 |
-32469848 |
AI271425 |
339483 |
1p35.1 |
Hs.471067 |
3 |
|
|
233566_at |
LOC84856 |
hypothetical LOC84856 |
10 |
42290944 |
AK024638 |
84856 |
10q11.21 |
Hs.55977 |
3 |
|
|
202288_at |
MTOR |
mechanistic target of rapamycin (serine/threonine kinase) |
1 |
-11089175 |
U88966 |
2475 |
1p36.2 |
Hs.338207 |
317 |
nucleotide binding protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum Golgi apparatus cytosol phosphoinositide 3-kinase complex signal transduction response to nutrient endomembrane system membrane cell growth kinase activity phosphotransferase activity, alcohol group as acceptor protein catabolic process TOR signaling pathway TORC1 complex TORC2 complex regulation of actin cytoskeleton organization response to amino acid stimulus protein amino acid autophosphorylation phosphoprotein binding |
ErbB signaling pathway mTOR signaling pathway Insulin signaling pathway Adipocytokine signaling pathway Type II diabetes mellitus Pathways in cancer Glioma Prostate cancer Acute myeloid leukemia |
203341_at |
CEBPZ |
CCAAT/enhancer binding protein (C/EBP), zeta |
2 |
-37282278 |
NM_005760 |
10153 |
2p22.2 |
Hs.135406 |
14 |
DNA binding binding nucleus transcription from RNA polymerase II promoter regulation of transcription |
|
223209_s_at |
SELS |
selenoprotein S |
15 |
-99629912, -99628736 |
AF328864 |
55829 |
15q26.3 |
Hs.32148 |
33 |
receptor activity endoplasmic reticulum anti-apoptosis inflammatory response redox signal response ER overload response selenium binding response to glucose stimulus membrane integral to membrane antioxidant activity enzyme binding integral to endoplasmic reticulum membrane ER-associated protein catabolic process endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production very-low-density lipoprotein particle low-density lipoprotein particle establishment of protein localization cell redox homeostasis |
|
239720_at |
GLP-1 |
GATA like protein-1 |
19 |
-10276478 |
AI923985 |
100125288 |
19p13.2 |
Hs.709296 |
11 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development zinc ion binding sequence-specific DNA binding metal ion binding |
|
208698_s_at |
NONO |
non-POU domain containing, octamer-binding |
X |
70419766 |
L14599 |
4841 |
Xq13.1 |
Hs.533282 Hs.700344 |
46 |
nucleotide binding DNA binding RNA binding nucleus DNA repair DNA recombination mRNA processing response to DNA damage stimulus RNA splicing identical protein binding regulation of transcription |
|
221514_at |
0.335 |
5.742 |
2.197 |
4.395e-02 |
0.579 |
-3.798 |
UTP14A |
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
X |
128867839 |
BC001149 |
10813 |
Xq26.1 |
Hs.458598 |
12 |
protein binding nucleus nucleolus rRNA processing small-subunit processome |
|
1553391_at |
-0.311 |
2.680 |
-2.498 |
2.443e-02 |
0.513 |
-3.310 |
CXorf58 |
chromosome X open reading frame 58 |
X |
23836043 |
NM_152761 |
254158 |
Xp22.11 |
Hs.351265 |
4 |
|
|
226035_at |
USP31 |
ubiquitin specific peptidase 31 |
16 |
-22980228 |
AA102581 |
57478 |
16p12.2 |
Hs.183817 |
8 |
ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity |
|
213688_at |
0.269 |
4.880 |
2.193 |
4.422e-02 |
0.579 |
-3.803 |
CALM1 |
calmodulin 1 (phosphorylase kinase, delta) |
14 |
89933125 |
N25325 |
801 |
14q24-q31 |
Hs.282410 Hs.708270 |
181 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
230679_at |
-0.313 |
3.507 |
-2.224 |
4.173e-02 |
0.574 |
-3.755 |
DCAF10 |
DDB1 and CUL4 associated factor 10 |
9 |
37790789 |
AA976778 |
79269 |
9p13.2 |
Hs.118394 |
2 |
|
|
217069_at |
MLL4 |
myeloid/lymphoid or mixed-lineage leukemia 4 |
19 |
40900760 |
AF105279 |
9757 |
19q13.1 |
Hs.676457 Hs.92236 |
15 |
transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent methyltransferase activity zinc ion binding chromatin modification transferase activity histone methyltransferase complex histone methyltransferase activity (H3-K4 specific) metal ion binding chromatin-mediated maintenance of transcription |
|
234854_at |
MDN1 |
MDN1, midasin homolog (yeast) |
6 |
-90409951 |
AL096678 |
23195 |
6q15 |
Hs.529948 |
7 |
nucleotide binding ATP binding nucleus ATPase activity regulation of protein complex assembly unfolded protein binding |
|
225464_at |
FRMD6 |
FERM domain containing 6 |
14 |
51025604, 51188325 |
N30138 |
122786 |
14q22.1 |
Hs.434914 |
9 |
binding cytoplasm mitochondrion cytoskeleton plasma membrane |
|
221168_at |
-0.249 |
3.146 |
-2.456 |
2.652e-02 |
0.522 |
-3.379 |
PRDM13 |
PR domain containing 13 |
6 |
100161370 |
NM_021620 |
59336 |
6q16-q21 |
Hs.287386 |
3 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
207081_s_at |
PI4KA |
phosphatidylinositol 4-kinase, catalytic, alpha |
22 |
-19391978, -19391978 |
NM_002650 |
5297 |
22q11.21 |
Hs.529438 |
29 |
nucleotide binding 1-phosphatidylinositol 4-kinase activity protein binding ATP binding Golgi-associated vesicle phosphatidylinositol biosynthetic process signal transduction synaptic transmission transferase activity phosphoinositide phosphorylation phosphoinositide-mediated signaling |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system |
1569827_at |
ATG7 |
ATG7 autophagy related 7 homolog (S. cerevisiae) |
3 |
11289009 |
BE048026 |
10533 |
3p25.3 |
Hs.716466 |
15 |
catalytic activity ubiquitin activating enzyme activity protein binding cytoplasm protein amino acid lipidation autophagy membrane fusion metabolic process protein transport modification-dependent protein catabolic process positive regulation of protein modification process protein homodimerization activity |
Regulation of autophagy |
211505_s_at |
STAU1 |
staufen, RNA binding protein, homolog 1 (Drosophila) |
20 |
-47163282 |
AL136601 |
6780 |
20q13.1 |
Hs.596704 |
26 |
double-stranded RNA binding protein binding intracellular rough endoplasmic reticulum microtubule associated complex intracellular mRNA localization ribonucleoprotein complex |
|
208867_s_at |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
AF119911 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
224862_at |
GNAQ |
guanine nucleotide binding protein (G protein), q polypeptide |
9 |
-79525010 |
BF969428 |
2776 |
9q21 |
Hs.269782 |
105 |
nucleotide binding skeletal system development regulation of action potential GTPase activity signal transducer activity protein binding GTP binding membrane fraction cytoplasm plasma membrane plasma membrane protein amino acid ADP-ribosylation signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway activation of phospholipase C activity glutamate signaling pathway heart development blood coagulation behavior post-embryonic development neuron remodeling guanyl nucleotide binding forebrain neuron development embryonic digit morphogenesis regulation of melanocyte differentiation pigmentation during development activation of phospholipase C activity by dopamine receptor signaling pathway |
Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease |
224282_s_at |
AGPAT3 |
1-acylglycerol-3-phosphate O-acyltransferase 3 |
21 |
44109543, 44169706 |
AB040138 |
56894 |
21q22.3 |
Hs.248785 |
9 |
1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum cytosol plasma membrane metabolic process acyltransferase activity phospholipid biosynthetic process integral to membrane transferase activity phospholipid:diacylglycerol acyltransferase activity |
Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Metabolic pathways |
218320_s_at |
NDUFB11 |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa |
X |
-46886559, -46886559 |
NM_019056 |
54539 |
Xp11.23 |
Hs.521969 |
9 |
mitochondrion mitochondrial inner membrane transport membrane integral to membrane electron transport chain respiratory chain |
|
224763_at |
0.334 |
6.833 |
2.192 |
4.431e-02 |
0.579 |
-3.804 |
RPL37 |
ribosomal protein L37 |
5 |
-40867186 |
BF724210 |
6167 |
5p13 |
Hs.558601 Hs.80545 |
12 |
structural constituent of ribosome protein binding intracellular cytosol ribosome translational elongation zinc ion binding rRNA binding cytosolic large ribosomal subunit metal ion binding |
Ribosome |
214340_at |
ALOX12P2 |
arachidonate 12-lipoxygenase pseudogene 2 |
17 |
6697618 |
AF020774 |
245 |
17p13 |
Hs.378695 |
3 |
|
|
39854_r_at |
-0.248 |
8.559 |
-2.174 |
4.586e-02 |
0.581 |
-3.833 |
PNPLA2 |
patatin-like phospholipase domain containing 2 |
11 |
808901 |
AF055000 |
57104 |
11p15.5 |
Hs.654697 |
30 |
triacylglycerol lipase activity lipid particle plasma membrane metabolic process negative regulation of sequestering of triglyceride positive regulation of triglyceride catabolic process integral to membrane lipid catabolic process hydrolase activity |
|
212402_at |
ZC3H13 |
zinc finger CCCH-type containing 13 |
13 |
-45434314 |
BE895685 |
23091 |
13q14.13 |
Hs.136102 |
11 |
nucleic acid binding zinc ion binding metal ion binding |
|
214587_at |
-0.263 |
2.318 |
-3.271 |
5.072e-03 |
0.345 |
-1.979 |
COL8A1 |
collagen, type VIII, alpha 1 |
3 |
100840143 |
BE877796 |
1295 |
3q12.3 |
Hs.654548 |
16 |
protein binding extracellular region collagen type VIII basement membrane cell adhesion positive regulation of cell-substrate adhesion camera-type eye morphogenesis epithelial cell proliferation |
|
1558768_at |
DNAH1 |
dynein, axonemal, heavy chain 1 |
3 |
52325374 |
AB037831 |
25981 |
3p21.1 |
Hs.655469 |
7 |
nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme |
Huntington's disease |
227632_at |
TBC1D24 |
TBC1 domain family, member 24 |
16 |
2465147 |
N74056 |
57465 |
16p13.3 |
Hs.353087 |
3 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
208111_at |
AVPR2 |
arginine vasopressin receptor 2 |
X |
152821178, 152823722 |
NM_000054 |
554 |
Xq28 |
Hs.567240 |
85 |
receptor activity G-protein coupled receptor activity vasopressin receptor activity endosome endoplasmic reticulum Golgi apparatus plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, coupled to cAMP nucleotide second messenger activation of adenylate cyclase activity excretion hemostasis positive regulation of gene expression |
Neuroactive ligand-receptor interaction |
224974_at |
SUDS3 |
suppressor of defective silencing 3 homolog (S. cerevisiae) |
12 |
117298740 |
AK024460 |
64426 |
12q24.23 |
Hs.416630 Hs.602312 |
9 |
protein binding negative regulation of transcription chromatin modification Sin3 complex histone deacetylase binding |
|
214229_at |
-0.177 |
3.405 |
-2.215 |
4.239e-02 |
0.575 |
-3.768 |
DNAH17 |
dynein, axonemal, heavy chain 17 |
17 |
|
AL122077 |
8632 |
17q25.3 |
Hs.375975 Hs.713207 |
7 |
nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme |
|
238444_at |
ZNF618 |
zinc finger protein 618 |
9 |
115678382 |
AV704303 |
114991 |
9q32 |
Hs.349208 |
2 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding protein dimerization activity |
|
220510_at |
RHBG |
Rh family, B glycoprotein (gene/pseudogene) |
1 |
154605626 |
NM_020407 |
57127 |
1q21.3 |
Hs.131835 |
16 |
plasma membrane integral to plasma membrane transport ammonium transmembrane transporter activity spectrin-associated cytoskeleton basolateral plasma membrane basolateral plasma membrane ankyrin binding cytoplasmic vesicle anchored to plasma membrane ammonia transporter activity ammonia transporter activity transepithelial ammonium transport |
|
232705_at |
LRRFIP2 |
leucine rich repeat (in FLII) interacting protein 2 |
3 |
-37069120 |
AK025207 |
9209 |
3p22.2 |
Hs.719246 |
7 |
protein binding cellular_component biological_process Wnt receptor signaling pathway LRR domain binding |
|
218989_x_at |
0.337 |
5.463 |
2.237 |
4.063e-02 |
0.570 |
-3.733 |
SLC30A5 |
solute carrier family 30 (zinc transporter), member 5 |
5 |
68425573, 68425637 |
NM_022902 |
64924 |
5q12.1 |
Hs.631975 |
10 |
zinc ion transmembrane transporter activity membrane fraction Golgi apparatus integral to plasma membrane cation transport cobalt ion transport zinc ion transport cellular zinc ion homeostasis zinc ion binding cation transmembrane transporter activity response to zinc ion regulation of proton transport membrane apical plasma membrane secretory granule |
|
205028_at |
TRO |
trophinin |
X |
54963973, 54963973 |
NM_016157 |
7216 |
Xp11.22-p11.21 |
Hs.633653 |
26 |
protein binding plasma membrane integral to plasma membrane cell adhesion homophilic cell adhesion embryo implantation |
|
1553362_at |
DNAH6 |
dynein, axonemal, heavy chain 6 |
2 |
84597089 |
NM_173645 |
1768 |
2p11.2 |
Hs.249972 |
7 |
nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement ATPase activity dynein complex |
|
207237_at |
-0.173 |
2.950 |
-2.301 |
3.592e-02 |
0.557 |
-3.631 |
KCNA3 |
potassium voltage-gated channel, shaker-related subfamily, member 3 |
1 |
-111015832 |
NM_002232 |
3738 |
1p13.3 |
Hs.169948 |
35 |
voltage-gated ion channel activity delayed rectifier potassium channel activity protein binding ion transport potassium ion transport voltage-gated potassium channel complex outward rectifier potassium channel activity membrane integral to membrane potassium ion binding |
|
207214_at |
SPINK4 |
serine peptidase inhibitor, Kazal type 4 |
9 |
33230195 |
NM_014471 |
27290 |
9p13.3 |
Hs.555934 |
7 |
serine-type endopeptidase inhibitor activity extracellular region nucleus peptidase inhibitor activity |
|
235114_x_at |
HOOK3 |
hook homolog 3 (Drosophila) |
8 |
42871189 |
N67300 |
84376 |
8p11.21 |
Hs.162852 |
13 |
cytoplasm Golgi apparatus cis-Golgi network cytoskeleton microtubule endosome organization lysosome organization microtubule binding endosome to lysosome transport protein transport HOPS complex cytoplasmic microtubule organization identical protein binding early endosome to late endosome transport Golgi localization FHF complex |
|
209147_s_at |
PPAP2A |
phosphatidic acid phosphatase type 2A |
5 |
-54756439 |
AB000888 |
8611 |
5q11 |
Hs.696231 |
20 |
membrane fraction cytosol plasma membrane integral to plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity negative regulation of cell proliferation germ cell migration hydrolase activity regulation of lipid metabolic process androgen receptor signaling pathway phospholipid dephosphorylation |
Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis |
225045_at |
CCDC88A |
coiled-coil domain containing 88A |
2 |
-55368483 |
AB033038 |
55704 |
2p16.1 |
Hs.292925 |
13 |
regulation of protein amino acid phosphorylation actin binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane regulation of DNA replication microtubule binding membrane organization cell migration lamellipodium lamellipodium assembly cytoplasmic vesicle activation of protein kinase B activity regulation of actin cytoskeleton organization phosphoinositide binding regulation of cell proliferation protein homodimerization activity protein kinase B binding |
|
237470_at |
DOCK7 |
dedicator of cytokinesis 7 |
1 |
-62692984 |
R45067 |
85440 |
1p31.3 |
Hs.406156 |
15 |
microtubule cytoskeleton organization guanyl-nucleotide exchange factor activity GTP binding multicellular organismal development nervous system development axonogenesis cell differentiation axon growth cone neuron projection development activation of Rac GTPase activity positive regulation of peptidyl-serine phosphorylation basal part of cell establishment of neuroblast polarity Rac GTPase binding GTPase binding |
|
1554415_at |
TAF5L |
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
1 |
-227801563, -227795486 |
BC041094 |
27097 |
1q42.13 |
Hs.270621 |
16 |
transcription factor activity transcription coactivator activity histone acetyltransferase activity nucleus transcription from RNA polymerase II promoter STAGA complex transcription factor TFTC complex histone H3 acetylation regulation of transcription |
Basal transcription factors |
1569354_at |
NSUN6 |
NOL1/NOP2/Sun domain family, member 6 |
10 |
-18874269 |
BC033534 |
221078 |
10p12.31 |
Hs.396175 |
4 |
RNA binding methyltransferase activity transferase activity |
|
213927_at |
MAP3K9 |
mitogen-activated protein kinase kinase kinase 9 |
14 |
-70264606 |
AV753204 |
4293 |
14q24.3-q31 |
Hs.445496 Hs.593542 |
9 |
nucleotide binding protein serine/threonine kinase activity JUN kinase kinase kinase activity MAP kinase kinase activity protein tyrosine kinase activity ATP binding cellular_component activation of JUN kinase activity transferase activity protein homodimerization activity protein amino acid autophosphorylation |
|
204469_at |
-0.214 |
2.139 |
-2.166 |
4.656e-02 |
0.582 |
-3.845 |
PTPRZ1 |
protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
7 |
121300394 |
NM_002851 |
5803 |
7q31.3 |
Hs.489824 |
42 |
transmembrane receptor protein tyrosine phosphatase activity protein binding cellular_component integral to plasma membrane protein amino acid dephosphorylation central nervous system development biological_process protein tyrosine/threonine phosphatase activity membrane hydrolase activity |
Epithelial cell signaling in Helicobacter pylori infection |
217503_at |
STK17B |
serine/threonine kinase 17b |
2 |
-196706552 |
AA203487 |
9262 |
2q32.3 |
Hs.710234 Hs.88297 |
7 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding nucleus protein amino acid phosphorylation apoptosis induction of apoptosis protein kinase cascade actin cytoskeleton transferase activity |
|
221687_s_at |
FAM125B |
family with sequence similarity 125, member B |
9 |
128128948, 128128948 |
BC000122 |
89853 |
9q33.3 |
Hs.162659 |
4 |
endosome protein transport membrane |
Endocytosis |
1556804_s_at |
0.418 |
2.600 |
2.324 |
3.438e-02 |
0.553 |
-3.595 |
POLR3B |
polymerase (RNA) III (DNA directed) polypeptide B |
12 |
105275565, 105275989 |
BC033542 |
55703 |
12q23.3 |
Hs.610795 Hs.62696 |
8 |
DNA binding DNA-directed RNA polymerase activity nucleus transcription zinc ion binding transferase activity nucleotidyltransferase activity ribonucleoside binding metal ion binding |
Purine metabolism Pyrimidine metabolism Metabolic pathways RNA polymerase |
214356_s_at |
KIAA0368 |
KIAA0368 |
9 |
-113162793 |
AI272899 |
23392 |
9q31.3 |
Hs.368255 |
12 |
proteasome complex binding nucleus early endosome late endosome endoplasmic reticulum ER-Golgi intermediate compartment trans-Golgi network centrosome cytosol cytoplasmic membrane-bounded vesicle ER to Golgi transport vesicle ER-associated protein catabolic process |
|
239546_at |
LOC100131053 |
hypothetical LOC100131053 |
1 |
|
AA404325 |
100131053 |
1p36.13 |
Hs.697104 |
1 |
|
|
222415_at |
MLL3 |
myeloid/lymphoid or mixed-lineage leukemia 3 |
7 |
-151462942 |
BE962679 |
58508 |
7q36.1 |
Hs.647120 |
21 |
DNA binding protein binding nucleus regulation of transcription, DNA-dependent intracellular signaling cascade methyltransferase activity zinc ion binding chromatin modification transferase activity histone-lysine N-methyltransferase activity metal ion binding |
|
200985_s_at |
CD59 |
CD59 molecule, complement regulatory protein |
11 |
-33681131, -33681131, -33681131 |
NM_000611 |
966 |
11p13 |
Hs.278573 Hs.709466 Hs.710641 |
107 |
protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane |
Complement and coagulation cascades Hematopoietic cell lineage |
227781_x_at |
FAM57B |
family with sequence similarity 57, member B |
16 |
-29943248 |
AL565715 |
83723 |
16p11.2 |
Hs.558560 |
8 |
endoplasmic reticulum membrane integral to membrane |
|
225368_at |
HIPK2 |
homeodomain interacting protein kinase 2 |
7 |
-138896855 |
BF218115 |
28996 |
7q32-q34 |
Hs.397465 Hs.632033 |
66 |
nucleotide binding transcription corepressor activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation apoptosis DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator induction of apoptosis by intracellular signals PML body transferase activity virus-host interaction positive regulation of transforming growth factor beta receptor signaling pathway nuclear membrane regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of JNK cascade virion binding |
|
225189_s_at |
RAPH1 |
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
2 |
-204014436, -204006783 |
AA194149 |
65059 |
2q33 |
Hs.471162 |
13 |
nucleus cytoplasm cytoskeleton plasma membrane cell-matrix adhesion signal transduction lamellipodium filopodium |
|
202233_s_at |
UQCRH |
ubiquinol-cytochrome c reductase hinge protein |
1 |
46541966 |
NM_006004 |
7388 |
1p34.1 |
Hs.481571 |
9 |
mitochondrion mitochondrial respiratory chain oxidative phosphorylation mitochondrial electron transport, ubiquinol to cytochrome c transport ubiquinol-cytochrome-c reductase activity aerobic respiration membrane electron transport chain |
Oxidative phosphorylation Metabolic pathways Cardiac muscle contraction Alzheimer's disease Parkinson's disease Huntington's disease |
201618_x_at |
0.268 |
7.420 |
2.471 |
2.575e-02 |
0.517 |
-3.354 |
GPAA1 |
glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) |
8 |
145209511 |
NM_003801 |
8733 |
8q24.3 |
Hs.627962 |
16 |
GPI-anchor transamidase activity protein binding endoplasmic reticulum protein complex assembly protein retention in ER lumen tubulin binding membrane integral to membrane attachment of GPI anchor to protein attachment of GPI anchor to protein attachment of GPI anchor to protein GPI anchor binding GPI-anchor transamidase complex |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Metabolic pathways |
1553555_at |
-0.368 |
4.425 |
-2.876 |
1.141e-02 |
0.426 |
-2.668 |
TAS2R38 |
taste receptor, type 2, member 38 |
7 |
-141318899 |
NM_176817 |
5726 |
7q34 |
Hs.647085 |
29 |
receptor activity G-protein coupled receptor activity signal transduction G-protein coupled receptor protein signaling pathway membrane integral to membrane response to stimulus sensory perception of taste |
Taste transduction |
1569938_at |
SIRT5 |
sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) |
6 |
13682770, 13682853 |
BC035196 |
23408 |
6p23 |
Hs.567431 Hs.594133 |
13 |
NAD+ ADP-ribosyltransferase activity mitochondrion chromatin silencing protein amino acid ADP-ribosylation protein amino acid deacetylation zinc ion binding hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides regulation of transcription metal ion binding NAD binding |
|
219574_at |
MARCH1 |
membrane-associated ring finger (C3HC4) 1 |
4 |
-164668498 |
NM_017923 |
55016 |
4q32.2-q32.3 |
Hs.608487 Hs.696248 |
5 |
zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process cytoplasmic vesicle metal ion binding |
|
209527_at |
EXOSC2 |
exosome component 2 |
9 |
132558978 |
BC000747 |
23404 |
9q34 |
Hs.654643 |
32 |
3'-5'-exoribonuclease activity exosome (RNase complex) exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing 7S RNA binding hydrolase activity |
RNA degradation |
227672_at |
C8orf73 |
chromosome 8 open reading frame 73 |
8 |
-144719505 |
W67308 |
642475 |
8q24.3 |
Hs.531406 |
3 |
binding Golgi apparatus |
|
222634_s_at |
0.462 |
4.726 |
2.604 |
1.979e-02 |
0.491 |
-3.133 |
TBL1XR1 |
transducin (beta)-like 1 X-linked receptor 1 |
3 |
-178221235 |
AF314544 |
79718 |
3q26.32 |
Hs.715537 |
14 |
nucleus chromatin modification modification-dependent protein catabolic process regulation of transcription |
Wnt signaling pathway |
227845_s_at |
SHD |
Src homology 2 domain containing transforming protein D |
19 |
4229597 |
AW452918 |
56961 |
19p13.3 |
Hs.7423 |
5 |
protein binding |
|
226925_at |
0.491 |
5.058 |
2.421 |
2.844e-02 |
0.532 |
-3.437 |
ACPL2 |
acid phosphatase-like 2 |
3 |
142433371 |
AW069729 |
92370 |
3q23 |
Hs.657887 |
2 |
acid phosphatase activity extracellular region hydrolase activity |
|
1570035_at |
TBC1D10A |
TBC1 domain family, member 10A |
22 |
-29017978 |
BC007908 |
83874 |
22q12.1-qter |
Hs.655273 |
13 |
Rab GTPase activator activity protein binding intracellular microvillus biological_process PDZ domain binding regulation of Rab GTPase activity |
|
221237_s_at |
OSBP2 |
oxysterol binding protein 2 |
22 |
29420792 |
NM_030758 |
23762 |
22q12.2 |
Hs.517546 |
11 |
lipid transport steroid metabolic process membrane |
|
221732_at |
-0.310 |
7.107 |
-2.585 |
2.055e-02 |
0.496 |
-3.165 |
CANT1 |
calcium activated nucleotidase 1 |
17 |
-74499392 |
AK026161 |
124583 |
17q25.3 |
Hs.8859 |
13 |
signal transducer activity calcium ion binding endoplasmic reticulum Golgi apparatus membrane integral to membrane hydrolase activity nucleoside-diphosphatase activity positive regulation of I-kappaB kinase/NF-kappaB cascade |
Purine metabolism Pyrimidine metabolism |
204528_s_at |
NAP1L1 |
nucleosome assembly protein 1-like 1 |
12 |
-74724938 |
NM_004537 |
4673 |
12q21.2 |
Hs.524599 Hs.695185 |
17 |
protein binding nucleus chromatin assembly complex DNA replication nucleosome assembly positive regulation of cell proliferation melanosome |
|
236292_at |
RNF130 |
ring finger protein 130 |
5 |
-179315079 |
AW196696 |
55819 |
5q35.3 |
Hs.484363 |
7 |
molecular_function protein binding apoptosis zinc ion binding membrane integral to membrane metal ion binding |
|
225302_at |
0.363 |
7.086 |
2.482 |
2.522e-02 |
0.514 |
-3.337 |
TMX3 |
thioredoxin-related transmembrane protein 3 |
18 |
-64491904 |
BE503286 |
54495 |
18q22 |
Hs.440534 |
11 |
protein disulfide isomerase activity endoplasmic reticulum membrane integral to membrane isomerase activity cell redox homeostasis |
|
216763_at |
-0.275 |
3.520 |
-2.508 |
2.394e-02 |
0.509 |
-3.293 |
KANK1 |
KN motif and ankyrin repeat domains 1 |
9 |
494702, 696895 |
AK025097 |
23189 |
9p24.3 |
Hs.306764 |
14 |
cytoplasm |
|
242469_at |
-0.260 |
5.067 |
-2.791 |
1.357e-02 |
0.438 |
-2.815 |
LOC120376 |
Uncharacterized protein LOC120376 |
11 |
110675185 |
AI590055 |
120376 |
11q23.1 |
Hs.31409 |
6 |
|
|
214756_x_at |
PMS2L1 |
postmeiotic segregation increased 2-like 1 pseudogene |
7 |
-99756198 |
AB017004 |
5379 |
7q22.1 |
Hs.634244 Hs.661055 Hs.709266 |
7 |
molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding |
|
227239_at |
FAM126A |
family with sequence similarity 126, member A |
7 |
-22947402 |
AV734839 |
84668 |
7p15.3 |
Hs.85603 |
9 |
signal transducer activity cellular_component cytoplasm biological_process membrane |
|
201950_x_at |
CAPZB |
capping protein (actin filament) muscle Z-line, beta |
1 |
-19537859 |
NM_004930 |
832 |
1p36.1 |
Hs.432760 |
10 |
actin binding protein binding cytoplasm cell motion F-actin capping protein complex actin cytoskeleton organization actin filament capping |
|
243829_at |
BRAF |
v-raf murine sarcoma viral oncogene homolog B1 |
7 |
-140080281 |
AW613053 |
673 |
7q34 |
Hs.550061 |
427 |
nucleotide binding protein serine/threonine kinase activity receptor signaling protein activity protein binding ATP binding nucleus cytoplasm plasma membrane protein amino acid phosphorylation anti-apoptosis small GTPase mediated signal transduction zinc ion binding organ morphogenesis transferase activity diacylglycerol binding metal ion binding |
MAPK signaling pathway ErbB signaling pathway Chemokine signaling pathway mTOR signaling pathway Vascular smooth muscle contraction Focal adhesion Natural killer cell mediated cytotoxicity Long-term potentiation Neurotrophin signaling pathway Long-term depression Regulation of actin cytoskeleton Insulin signaling pathway Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Thyroid cancer Melanoma Bladder cancer Chronic myeloid leukemia Acute myeloid leukemia Non-small cell lung cancer |
219415_at |
TTYH1 |
tweety homolog 1 (Drosophila) |
19 |
59618446 |
NM_020659 |
57348 |
19q13.4 |
Hs.268728 |
4 |
ion channel activity chloride channel activity iron ion transmembrane transporter activity protein binding plasma membrane ion transport iron ion transport cell adhesion integral to membrane chloride ion binding chloride channel complex |
|
212776_s_at |
OBSL1 |
obscurin-like 1 |
2 |
-220123708 |
AI978623 |
23363 |
2q35 |
Hs.526594 |
10 |
cytoskeleton organization cytoskeletal adaptor activity intercalated disc Z disc M band perinuclear region of cytoplasm cardiac myofibril assembly |
|
243313_at |
SYNPO2L |
synaptopodin 2-like |
10 |
-75074649, -75074649 |
AI141151 |
79933 |
10q22.2 |
Hs.645273 |
4 |
actin binding protein binding cytoplasm cytoskeleton |
|
212919_at |
DCP2 |
DCP2 decapping enzyme homolog (S. cerevisiae) |
5 |
112340331 |
AV715578 |
167227 |
5q22.2 |
Hs.443875 |
21 |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasmic mRNA processing body RNA binding protein binding nucleus cytoplasm hydrolase activity manganese ion binding metal ion binding |
RNA degradation |
200642_at |
0.287 |
11.065 |
2.420 |
2.847e-02 |
0.532 |
-3.438 |
SOD1 |
superoxide dismutase 1, soluble |
21 |
31953805 |
NM_000454 |
6647 |
21q22.1 21q22.11 |
Hs.443914 |
450 |
activation of MAPK activity response to superoxide ovarian follicle development positive regulation of cytokine production placenta development retina homeostasis myeloid cell homeostasis superoxide dismutase activity copper ion binding extracellular space nucleus cytoplasm mitochondrion mitochondrial matrix peroxisome cytosol plasma membrane double-strand break repair DNA fragmentation involved in apoptosis glutathione metabolic process cellular iron ion homeostasis anti-apoptosis spermatogenesis embryo implantation embryo implantation cell aging cell aging sensory perception of sound locomotory behavior regulation of blood pressure cell death zinc ion binding response to heat antioxidant activity oxidoreductase activity transmission of nerve impulse removal of superoxide radicals protein phosphatase 2B binding extracellular matrix cytoplasmic vesicle response to nutrient levels myelin maintenance in the peripheral nervous system dendrite cytoplasm regulation of T cell differentiation in the thymus regulation of multicellular organism growth response to drug response to hydrogen peroxide superoxide anion generation protein homodimerization activity cell soma positive regulation of apoptosis positive regulation of catalytic activity protein complex negative regulation of neuron apoptosis response to ethanol negative regulation of cholesterol biosynthetic process regulation of protein kinase activity regulation of organ growth response to copper ion muscle maintenance metal ion binding thymus development response to axon injury hydrogen peroxide biosynthetic process hydrogen peroxide biosynthetic process chaperone binding regulation of mitochondrial membrane potential oxidation reduction heart contraction neurofilament cytoskeleton organization relaxation of vascular smooth muscle auditory receptor cell stereocilium organization |
Amyotrophic lateral sclerosis (ALS) Huntington's disease Prion diseases |
238765_at |
ATP6V1G1 |
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 |
9 |
116389814 |
AA732007 |
9550 |
9q32 |
Hs.388654 |
18 |
protein binding intracellular lysosomal membrane cytosol plasma membrane plasma membrane ion transport hydrogen-exporting ATPase activity, phosphorylative mechanism proton transport vacuolar proton-transporting V-type ATPase complex hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATPase activity ATPase binding |
Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection |
218154_at |
GSDMD |
gasdermin D |
8 |
144711634 |
NM_024736 |
79792 |
8q24.3 |
Hs.118983 |
8 |
cellular response to extracellular stimulus |
|
205022_s_at |
FOXN3 |
forkhead box N3 |
14 |
-88692268, -88692268 |
NM_005197 |
1112 |
14q31.3 |
Hs.434286 Hs.621371 |
16 |
DNA damage checkpoint G2 phase of mitotic cell cycle transcription factor activity nucleus cell cycle protein C-terminus binding transcription repressor activity sequence-specific DNA binding negative regulation of transcription, DNA-dependent |
|
235049_at |
-0.359 |
5.891 |
-2.356 |
3.229e-02 |
0.546 |
-3.543 |
ADCY1 |
adenylate cyclase 1 (brain) |
7 |
45580649 |
AA021120 |
107 |
7p13-p12 |
Hs.192215 |
24 |
nucleotide binding magnesium ion binding calmodulin binding ATP binding cAMP biosynthetic process long-term memory calcium- and calmodulin-responsive adenylate cyclase activity hormone-mediated signaling membrane integral to membrane |
Purine metabolism Calcium signaling pathway Chemokine signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation GnRH signaling pathway Melanogenesis |
214730_s_at |
GLG1 |
golgi apparatus protein 1 |
16 |
-73038828 |
AK025457 |
2734 |
16q22.3 |
Hs.109731 |
17 |
Golgi membrane receptor binding Golgi apparatus membrane integral to membrane |
Cell adhesion molecules (CAMs) |
219457_s_at |
RIN3 |
Ras and Rab interactor 3 |
14 |
92049877 |
NM_024832 |
79890 |
14q32.12 |
Hs.326822 |
8 |
GTPase activator activity protein binding cellular_component cytoplasm early endosome endocytosis signal transduction Ras GTPase binding cytoplasmic vesicle |
|
219795_at |
-0.201 |
2.146 |
-2.174 |
4.585e-02 |
0.581 |
-3.833 |
SLC6A14 |
solute carrier family 6 (amino acid transporter), member 14 |
X |
115481801 |
NM_007231 |
11254 |
Xq23-q24 |
Hs.522109 |
13 |
neurotransmitter:sodium symporter activity integral to plasma membrane cellular amino acid metabolic process neurotransmitter transport amino acid transport amino acid transmembrane transporter activity symporter activity membrane brush border membrane |
|
202589_at |
0.554 |
3.988 |
2.770 |
1.417e-02 |
0.445 |
-2.851 |
TYMS |
thymidylate synthetase |
18 |
647603 |
NM_001071 |
7298 |
18p11.32 |
Hs.592338 |
260 |
thymidylate synthase activity thymidylate synthase activity cytosol nucleobase, nucleoside, nucleotide and nucleic acid metabolic process dTMP biosynthetic process DNA replication DNA repair methyltransferase activity deoxyribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process transferase activity response to organophosphorus phosphoinositide-mediated signaling |
Pyrimidine metabolism One carbon pool by folate Metabolic pathways |
200748_s_at |
0.545 |
12.251 |
3.473 |
3.347e-03 |
0.308 |
-1.625 |
FTH1 |
ferritin, heavy polypeptide 1 |
11 |
-61488332 |
NM_002032 |
2495 |
11q13 |
Hs.524910 Hs.645560 |
55 |
ferroxidase activity protein binding iron ion transport intracellular sequestering of iron ion immune response intracellular ferritin complex ferric iron binding negative regulation of cell proliferation oxidoreductase activity oxidation reduction |
Porphyrin and chlorophyll metabolism |
205489_at |
2.640 |
7.246 |
4.200 |
7.505e-04 |
0.211 |
-0.358 |
CRYM |
crystallin, mu |
16 |
-21177342, -21177342 |
NM_001888 |
1428 |
16p13.11-p12.3 |
Hs.924 |
17 |
negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity catalytic activity cytoplasm sensory perception of sound metabolic process thyroid hormone metabolic process protein homodimerization activity NADP or NADPH binding thyroid hormone binding thyroid hormone binding thyroid hormone transport |
|
213097_s_at |
DNAJC2 |
DnaJ (Hsp40) homolog, subfamily C, member 2 |
7 |
-102740156 |
AI338837 |
27000 |
7q22 |
Hs.558476 |
11 |
DNA binding nucleus protein folding heat shock protein binding unfolded protein binding |
|
235212_at |
C14orf102 |
chromosome 14 open reading frame 102 |
14 |
-89814150 |
AA346979 |
55051 |
14q32.11 |
Hs.528131 |
4 |
protein binding |
|
1554360_at |
FCHSD2 |
FCH and double SH3 domains 2 |
11 |
-72225437 |
BC010394 |
9873 |
11q13.4 |
Hs.577053 |
9 |
protein binding |
|
236523_at |
LOC285556 |
hypothetical protein LOC285556 |
4 |
|
BF435831 |
285556 |
4q23 |
Hs.480371 |
|
|
|
230645_at |
FRMD3 |
FERM domain containing 3 |
9 |
-85052126 |
BF110588 |
257019 |
9q21.32 |
Hs.709357 |
7 |
binding cytoplasm cytoskeleton cytoskeletal protein binding membrane integral to membrane extrinsic to membrane |
|
224163_s_at |
DMAP1 |
DNA methyltransferase 1 associated protein 1 |
1 |
44451711 |
AL136657 |
55929 |
1p34 |
Hs.8008 |
24 |
DNA binding protein binding nucleus DNA methylation negative regulation of transcription transcription repressor activity chromatin modification NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation |
|
229861_at |
RFFL |
ring finger and FYVE-like domain containing 1 |
17 |
-30360243, -30360243 |
N66669 |
117584 |
17q12 |
Hs.13680 |
11 |
protein binding cytoplasm intracellular protein transport apoptosis zinc ion binding membrane cytoplasmic membrane-bounded vesicle ligase activity modification-dependent protein catabolic process metal ion binding |
|
243365_s_at |
AUTS2 |
autism susceptibility candidate 2 |
7 |
68701840, 68701841, 68701841 |
AI417756 |
26053 |
7q11.22 |
Hs.654801 Hs.712991 |
13 |
molecular_function cellular_component biological_process |
|
204436_at |
PLEKHO2 |
pleckstrin homology domain containing, family O member 2 |
15 |
62921134 |
NM_025201 |
80301 |
15q22.1 |
Hs.709337 |
2 |
|
Cytokine-cytokine receptor interaction |
201319_at |
MYL12A |
myosin, light chain 12A, regulatory, non-sarcomeric |
18 |
3237527 |
NM_006471 |
10627 |
18p11.31 |
Hs.190086 |
9 |
motor activity calcium ion binding protein binding myosin complex |
Focal adhesion Tight junction Leukocyte transendothelial migration Regulation of actin cytoskeleton |
243311_at |
-0.207 |
3.671 |
-2.327 |
3.418e-02 |
0.553 |
-3.590 |
DEFB132 |
defensin, beta 132 |
20 |
186376 |
BE044548 |
400830 |
20p13 |
Hs.516819 |
7 |
extracellular region defense response to bacterium |
|
210038_at |
PRKCQ |
protein kinase C, theta |
10 |
-6509110 |
AL137145 |
5588 |
10p15 |
Hs.498570 |
112 |
nucleotide binding magnesium ion binding regulation of cell growth protein kinase C activity protein binding ATP binding intracellular protein amino acid phosphorylation membrane protein ectodomain proteolysis intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding |
Vascular smooth muscle contraction Tight junction T cell receptor signaling pathway Adipocytokine signaling pathway |
222400_s_at |
ADI1 |
acireductone dioxygenase 1 |
2 |
-3480696 |
BC001467 |
55256 |
2p25.3 |
Hs.502773 |
13 |
protein binding nucleus cytoplasm plasma membrane cellular amino acid biosynthetic process methionine biosynthetic process nickel ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen methionine salvage metal ion binding oxidation reduction |
Cysteine and methionine metabolism Metabolic pathways |
234871_at |
GPR98 |
G protein-coupled receptor 98 |
5 |
89890372 |
AL133041 |
84059 |
5q13 |
Hs.591777 |
23 |
G-protein coupled receptor activity calcium ion binding cytoplasm plasma membrane neuropeptide signaling pathway nervous system development cell surface integral to membrane integral to membrane cell-cell adhesion photoreceptor cell maintenance maintenance of organ identity inner ear development neurological system process response to stimulus detection of mechanical stimulus involved in sensory perception of sound |
|
214476_at |
TFF2 |
trefoil factor 2 |
21 |
-42639537 |
NM_005423 |
7032 |
21q22.3 |
Hs.2979 |
44 |
extracellular region digestion |
|
201289_at |
1.679 |
6.609 |
2.590 |
2.032e-02 |
0.494 |
-3.155 |
CYR61 |
cysteine-rich, angiogenic inducer, 61 |
1 |
85819031 |
NM_001554 |
3491 |
1p31-p22 |
Hs.8867 |
82 |
regulation of cell growth patterning of blood vessels insulin-like growth factor binding extracellular region chemotaxis cell adhesion heparin binding cell proliferation anatomical structure morphogenesis positive regulation of cell-substrate adhesion extracellular matrix organization extracellular matrix binding |
|
218252_at |
0.522 |
5.045 |
2.347 |
3.288e-02 |
0.550 |
-3.558 |
CKAP2 |
cytoskeleton associated protein 2 |
13 |
51927495 |
NM_018204 |
26586 |
13q14 |
Hs.444028 Hs.449585 Hs.711762 |
17 |
cytoplasm cytoskeleton microtubule apoptosis cell cycle |
|
206304_at |
MYBPH |
myosin binding protein H |
1 |
-201403561 |
NM_004997 |
4608 |
1q32.1 |
Hs.927 |
6 |
protein binding striated muscle thick filament regulation of striated muscle contraction cell adhesion structural constituent of muscle |
|
1554334_a_at |
DNAJA4 |
DnaJ (Hsp40) homolog, subfamily A, member 4 |
15 |
76343541, 76344043, 76345614 |
BC031044 |
55466 |
15q25.1 |
Hs.513053 |
5 |
protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding |
|
211609_x_at |
PSMD4 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 |
1 |
149493820 |
U51007 |
5710 |
1q21.3 |
Hs.505059 |
62 |
proteasome complex protein binding cytosol anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
203730_s_at |
0.369 |
4.232 |
2.208 |
4.297e-02 |
0.576 |
-3.779 |
ZKSCAN5 |
zinc finger with KRAB and SCAN domains 5 |
7 |
98940208, 98940508 |
BF196931 |
23660 |
7q22 |
Hs.110839 |
9 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
234971_x_at |
PLCD3 |
phospholipase C, delta 3 |
17 |
-40544533 |
AI521584 |
113026 |
17q21.31 |
Hs.380094 |
20 |
angiogenesis placenta development phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cytoplasm intracellular signaling cascade membrane lipid catabolic process hydrolase activity |
Inositol phosphate metabolism Metabolic pathways Calcium signaling pathway Phosphatidylinositol signaling system |
229222_at |
ACSS3 |
acyl-CoA synthetase short-chain family member 3 |
12 |
79995939 |
AI123815 |
79611 |
12q21.31 |
Hs.259559 |
2 |
nucleotide binding acetate-CoA ligase activity ATP binding mitochondrion metabolic process ligase activity |
Propanoate metabolism Metabolic pathways |
222834_s_at |
0.846 |
5.748 |
3.827 |
1.612e-03 |
0.259 |
-1.004 |
GNG12 |
guanine nucleotide binding protein (G protein), gamma 12 |
1 |
-67939736 |
N32508 |
55970 |
1p31.3 |
Hs.431101 |
17 |
signal transducer activity heterotrimeric G-protein complex plasma membrane signal transduction G-protein coupled receptor protein signaling pathway hormone-mediated signaling |
MAPK signaling pathway Chemokine signaling pathway Regulation of actin cytoskeleton |
213601_at |
SLIT1 |
slit homolog 1 (Drosophila) |
10 |
-98747784 |
AB011537 |
6585 |
10q23.3-q24 |
Hs.632082 |
16 |
calcium ion binding protein binding extracellular region extracellular space multicellular organismal development nervous system development brain development cell differentiation retinal ganglion cell axon guidance establishment of nucleus localization intracellular membrane-bounded organelle |
Axon guidance |
1554555_a_at |
SETD6 |
SET domain containing 6 |
16 |
57106883 |
BC022451 |
79918 |
16q21 |
Hs.592060 |
5 |
|
|
1561503_at |
-1.435 |
8.934 |
-3.335 |
4.448e-03 |
0.330 |
-1.867 |
MYLK4 |
myosin light chain kinase family, member 4 |
6 |
-2608861 |
AK096893 |
340156 |
6p25.2 |
Hs.127830 |
4 |
nucleotide binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity |
|
217115_at |
LOC100240726 |
makorin ring finger protein 1 pseudogene |
20 |
-44525707 |
AL031686 |
100240726 |
20q13.12 |
|
1 |
|
|
231128_at |
FAM181B |
family with sequence similarity 181, member B |
11 |
-82120693 |
BE858471 |
220382 |
11q14.1 |
Hs.448218 |
2 |
|
|
216233_at |
CD163 |
CD163 molecule |
12 |
-7514676 |
Z22970 |
9332 |
12p13.3 |
Hs.504641 |
51 |
scavenger receptor activity protein binding extracellular region plasma membrane integral to plasma membrane acute-phase response inflammatory response |
|
228469_at |
PPID |
peptidylprolyl isomerase D |
4 |
-159849728 |
BF431902 |
5481 |
4q31.3 |
Hs.581725 |
25 |
peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding |
Calcium signaling pathway Parkinson's disease Huntington's disease |
210495_x_at |
1.039 |
8.987 |
3.984 |
1.168e-03 |
0.231 |
-0.732 |
FN1 |
fibronectin 1 |
2 |
-215987628, -215933423 |
AF130095 |
2335 |
2q34 |
Hs.203717 |
291 |
extracellular matrix structural constituent collagen binding extracellular region extracellular region fibrinogen complex proteinaceous extracellular matrix ER-Golgi intermediate compartment acute-phase response cell adhesion heparin binding regulation of cell shape response to wounding cell migration peptide cross-linking platelet alpha granule lumen substrate adhesion-dependent cell spreading |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer |
202322_s_at |
0.371 |
8.013 |
3.042 |
8.134e-03 |
0.387 |
-2.381 |
GGPS1 |
geranylgeranyl diphosphate synthase 1 |
1 |
233558375, 233558491 |
NM_004837 |
9453 |
1q43 |
Hs.719270 |
13 |
dimethylallyltranstransferase activity farnesyltranstransferase activity geranyltranstransferase activity soluble fraction cytoplasm isoprenoid biosynthetic process transferase activity |
Terpenoid backbone biosynthesis Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
236979_at |
BCL2L15 |
BCL2-like 15 |
1 |
-114220958 |
AI821801 |
440603 |
1p13.2 |
Hs.123106 |
7 |
apoptosis |
|
243821_at |
MRPS31 |
mitochondrial ribosomal protein S31 |
13 |
-40201431 |
AL120564 |
10240 |
13q14.11 |
Hs.154655 |
8 |
mitochondrion ribosome protein domain specific binding |
|
212508_at |
MOAP1 |
modulator of apoptosis 1 |
14 |
-92718293 |
AK024029 |
64112 |
14q32 |
Hs.24719 |
15 |
protein binding cytoplasm activation of caspase activity cell structure disassembly during apoptosis apoptotic nuclear changes protein homodimerization activity |
|
227182_at |
SUSD3 |
sushi domain containing 3 |
9 |
94860809 |
AW966474 |
203328 |
9q22.31 |
Hs.88417 |
4 |
membrane integral to membrane |
|
236859_at |
RUNX2 |
runt-related transcription factor 2 |
6 |
45404031, 45497891 |
AW469546 |
860 |
6p21 |
Hs.535845 |
152 |
osteoblast differentiation transcription factor activity RNA polymerase II transcription factor activity protein binding ATP binding nucleus regulation of transcription, DNA-dependent negative regulation of transcription transcription activator activity |
|
223310_x_at |
PNPLA8 |
patatin-like phospholipase domain containing 8 |
7 |
-107899306 |
AF217519 |
50640 |
7q31 |
Hs.617340 |
13 |
lysophospholipase activity binding ATP binding intracellular intracellular membrane fraction membrane fraction cytoplasm peroxisomal membrane peroxisomal membrane endoplasmic reticulum Golgi apparatus fatty acid metabolic process fatty acid metabolic process metabolic process membrane integral to membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity calcium-independent phospholipase A2 activity perinuclear region of cytoplasm |
|
223330_s_at |
SUGT1 |
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) |
13 |
52124831 |
BC000911 |
10910 |
13q14.3 |
Hs.281902 |
13 |
ubiquitin ligase complex kinetochore binding mitosis modification-dependent protein catabolic process |
|
1558698_at |
ZNF264 |
zinc finger protein 264 |
19 |
62394680 |
BF971035 |
9422 |
19q13.4 |
Hs.515634 |
8 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
218973_at |
EFTUD1 |
elongation factor Tu GTP binding domain containing 1 |
15 |
-80209615 |
NM_024580 |
79631 |
15q25.2 |
Hs.459114 |
4 |
nucleotide binding translation elongation factor activity GTPase activity GTP binding translation |
|
204552_at |
INPP4A |
inositol polyphosphate-4-phosphatase, type I, 107kDa |
2 |
98427752, 98427752 |
AA355179 |
3631 |
2q11.2 |
Hs.469386 |
16 |
signal transduction phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system |
217332_at |
RP11-159J2.1 |
CTAGE family, member 5 pseudogene |
13 |
-74709889 |
AL133018 |
647288 |
13q22.2 |
Hs.567920 |
|
|
|
1553262_a_at |
-0.280 |
6.284 |
-2.800 |
1.332e-02 |
0.435 |
-2.799 |
UTS2R |
urotensin 2 receptor |
17 |
77925489 |
NM_018949 |
2837 |
17q25.3 |
Hs.192720 |
21 |
urotensin II receptor activity receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway blood circulation integral to membrane |
Neuroactive ligand-receptor interaction |
214017_s_at |
DHX34 |
DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
19 |
52544385 |
AA039439 |
9704 |
19q13.3 |
Hs.151706 |
7 |
nucleotide binding RNA binding helicase activity ATP binding hydrolase activity |
|
210426_x_at |
0.721 |
5.791 |
3.034 |
8.267e-03 |
0.387 |
-2.395 |
RORA |
RAR-related orphan receptor A |
15 |
-58567776, -58567776, -58567776 |
U04897 |
6095 |
15q22.2 |
Hs.560343 Hs.655155 |
33 |
transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding |
|
200769_s_at |
MAT2A |
methionine adenosyltransferase II, alpha |
2 |
85619798 |
NM_005911 |
4144 |
2p11.2 |
Hs.516157 |
18 |
nucleotide binding magnesium ion binding methionine adenosyltransferase activity protein binding ATP binding S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to light stimulus response to hormone stimulus transferase activity potassium ion binding response to drug cobalt ion binding response to cAMP |
Cysteine and methionine metabolism Selenoamino acid metabolism Biosynthesis of plant hormones Metabolic pathways |
1563478_at |
KIAA1671 |
KIAA1671 |
22 |
23753940 |
AL832019 |
85379 |
22q11.23 |
Hs.419171 |
4 |
|
|
227056_at |
0.443 |
4.845 |
2.254 |
3.936e-02 |
0.567 |
-3.707 |
KIAA0141 |
KIAA0141 |
5 |
141283568 |
AA181172 |
9812 |
5q31.3 |
Hs.210532 |
6 |
binding mitochondrion |
|
235766_x_at |
-0.506 |
4.068 |
-2.307 |
3.553e-02 |
0.556 |
-3.622 |
RAB27A |
RAB27A, member RAS oncogene family |
15 |
-53283091, -53283091, -53283091, -53283091 |
AA743462 |
5873 |
15q15-q21.1 |
Hs.654978 |
60 |
nucleotide binding GTPase activity protein binding GTP binding exocytosis small GTPase mediated signal transduction protein transport membrane dendrite melanosome exocytic vesicle |
|
213842_x_at |
NSUN5C |
NOL1/NOP2/Sun domain family, member 5C |
7 |
-72056767 |
AK021688 |
260294 |
7q11.23 |
Hs.510927 |
5 |
methyltransferase activity transferase activity |
|
1553593_a_at |
TAL2 |
T-cell acute lymphocytic leukemia 2 |
9 |
107464558 |
NM_005421 |
6887 |
9q32 |
Hs.247978 |
9 |
DNA binding protein binding nucleus behavior post-embryonic development thalamus development transcription regulator activity midbrain development multicellular organism growth regulation of transcription |
|
210499_s_at |
PQBP1 |
polyglutamine binding protein 1 |
X |
48640138, 48640482 |
AB041834 |
10084 |
Xp11.23 |
Hs.534384 |
26 |
DNA binding transcription coactivator activity protein binding nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent |
|
229209_at |
SNHG10 |
small nucleolar RNA host gene 10 (non-protein coding) |
14 |
-95069001 |
AI302707 |
283596 |
14q32.13 |
Hs.448753 |
3 |
|
|
226049_at |
ERC1 |
ELKS/RAB6-interacting/CAST family member 1 |
12 |
970664 |
AI271420 |
23085 |
12p13.3 |
Hs.655744 Hs.658200 |
19 |
protein binding cytoplasm Golgi apparatus regulation of transcription, DNA-dependent I-kappaB phosphorylation multicellular organismal development IkappaB kinase complex protein transport Rab GTPase binding retrograde transport, endosome to Golgi presynaptic membrane leucine zipper domain binding positive regulation of anti-apoptosis positive regulation of NF-kappaB transcription factor activity |
|
218744_s_at |
PACSIN3 |
protein kinase C and casein kinase substrate in neurons 3 |
11 |
-47155656 |
NM_016223 |
29763 |
11p12-p11.12 |
Hs.334639 |
14 |
cytoplasm plasma membrane cytoskeletal protein binding negative regulation of endocytosis positive regulation of membrane protein ectodomain proteolysis |
|
226210_s_at |
MEG3 |
maternally expressed 3 (non-protein coding) |
14 |
100362197, 100362215 |
AI291123 |
55384 |
14q32 |
Hs.525589 Hs.593706 Hs.654863 Hs.655127 |
11 |
|
|
1556060_a_at |
ZNF451 |
zinc finger protein 451 |
6 |
57062786 |
AK027074 |
26036 |
6p12.1-p11.2 |
Hs.485628 Hs.705485 |
13 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
226109_at |
C21orf91 |
chromosome 21 open reading frame 91 |
21 |
-18083154 |
AK023825 |
54149 |
21q21.1 |
Hs.293811 |
8 |
|
|
209659_s_at |
CDC16 |
cell division cycle 16 homolog (S. cerevisiae) |
13 |
114018463 |
AF164598 |
8881 |
13q34 |
Hs.374127 |
32 |
binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
212264_s_at |
WAPAL |
wings apart-like homolog (Drosophila) |
10 |
-88184992 |
BE645850 |
23063 |
10q23.2 |
Hs.203099 Hs.714876 |
14 |
protein binding nucleus interspecies interaction between organisms |
|
200922_at |
KDELR1 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
19 |
-53577638 |
NM_006801 |
10945 |
19q13.3 |
Hs.515515 |
14 |
receptor activity KDEL sequence binding protein binding membrane fraction endoplasmic reticulum ER-Golgi intermediate compartment protein retention in ER lumen intracellular protein transport membrane integral to membrane vesicle-mediated transport |
Vibrio cholerae infection |
212276_at |
LPIN1 |
lipin 1 |
2 |
11804190 |
D80010 |
23175 |
2p25.1 |
Hs.467740 |
28 |
molecular_function nucleus lipid metabolic process phosphatidate phosphatase activity ruffle organization actin cytoskeleton reorganization cellular response to insulin stimulus regulation of fat cell differentiation |
|
211194_s_at |
TP63 |
tumor protein p63 |
3 |
190831909, 190831909, 190990142, 190990142 |
AB010153 |
8626 |
3q28 |
Hs.137569 |
238 |
response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization |
|
214869_x_at |
0.285 |
6.059 |
2.940 |
1.001e-02 |
0.414 |
-2.557 |
GAPVD1 |
GTPase activating protein and VPS9 domains 1 |
9 |
127063931 |
AK021533 |
26130 |
9q33.3 |
Hs.495134 |
9 |
guanyl-nucleotide exchange factor activity GTPase activator activity intracellular endosome cytosol endocytosis signal transduction membrane GTPase activating protein binding regulation of small GTPase mediated signal transduction regulation of protein transport |
|
231973_s_at |
0.566 |
4.745 |
2.320 |
3.463e-02 |
0.554 |
-3.601 |
ANAPC1 |
anaphase promoting complex subunit 1 |
2 |
-112243110 |
AK001223 |
64682 |
2q12.1 |
Hs.436527 |
26 |
nucleoplasm cytosol cell cycle mitosis modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
243564_at |
PDE1C |
phosphodiesterase 1C, calmodulin-dependent 70kDa |
7 |
-31795771 |
BE784669 |
5137 |
7p14.3 |
Hs.655694 |
10 |
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding signal transduction hydrolase activity |
Purine metabolism Calcium signaling pathway Olfactory transduction |
238111_at |
SDCCAG3 |
serologically defined colon cancer antigen 3 |
9 |
-138416194 |
AA829654 |
10807 |
9q34.3 |
Hs.94300 |
7 |
cytoplasm |
|
1558691_a_at |
-0.203 |
3.860 |
-2.139 |
4.904e-02 |
0.590 |
-3.888 |
DOCK4 |
dedicator of cytokinesis 4 |
7 |
-111153399 |
AV691156 |
9732 |
7q31.1 |
Hs.654652 |
16 |
guanyl-nucleotide exchange factor activity protein binding membrane SH3 domain binding PDZ domain binding Rac GTPase activator activity stereocilium Rac GTPase binding |
|
232224_at |
MASP1 |
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
3 |
-188447299, -188434565, -188418631 |
AI274095 |
5648 |
3q27-q28 |
Hs.89983 |
30 |
complement activation, lectin pathway complement activation, lectin pathway serine-type endopeptidase activity calcium ion binding extracellular region extracellular region extracellular space proteolysis peptidase activity protein homodimerization activity calcium-dependent protein binding |
Complement and coagulation cascades |
208209_s_at |
C4BPB |
complement component 4 binding protein, beta |
1 |
205328834, 205329206, 205329250 |
NM_000716 |
725 |
1q32 |
Hs.99886 |
23 |
extracellular region complement activation, classical pathway blood coagulation innate immune response |
Complement and coagulation cascades |
227681_at |
ZFP36L2 |
zinc finger protein 36, C3H type-like 2 |
2 |
-43303044 |
BF589368 |
678 |
2p22.3-p21 |
Hs.503093 |
8 |
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay transcription factor activity RNA binding nucleus cytoplasm zinc ion binding cell proliferation regulation of mRNA stability metal ion binding |
|
208993_s_at |
PPIG |
peptidylprolyl isomerase G (cyclophilin G) |
2 |
170149095 |
AW340788 |
9360 |
2q31.1 |
Hs.470544 |
10 |
peptidyl-prolyl cis-trans isomerase activity nucleus nucleoplasm protein folding RNA splicing cyclosporin A binding nuclear matrix nuclear speck isomerase activity |
|
238149_at |
0.431 |
2.307 |
2.625 |
1.895e-02 |
0.488 |
-3.097 |
ZNF818P |
zinc finger protein 818 pseudogene |
19 |
|
AI651641 |
390963 |
19q13.42 |
Hs.444446 |
|
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
208186_s_at |
LIPE |
lipase, hormone-sensitive |
19 |
-47597505 |
NM_005357 |
3991 |
19q13.2 |
Hs.656980 |
74 |
triacylglycerol lipase activity protein binding cytoplasm cytosol plasma membrane caveola protein amino acid phosphorylation metabolic process steroid metabolic process cholesterol metabolic process lipid catabolic process hydrolase activity triglyceride catabolic process hormone-sensitive lipase activity diacylglycerol catabolic process |
Insulin signaling pathway |
244209_at |
LOC282992 |
hypothetical protein LOC282992 |
10 |
|
AI655594 |
282992 |
10q24.31 |
Hs.386143 Hs.713042 |
1 |
|
|
227195_at |
0.819 |
5.934 |
3.405 |
3.847e-03 |
0.319 |
-1.744 |
ZNF503 |
zinc finger protein 503 |
10 |
-76827610 |
AA603467 |
84858 |
10q22.2 |
Hs.195710 |
6 |
intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
219067_s_at |
0.246 |
6.848 |
2.347 |
3.289e-02 |
0.550 |
-3.558 |
NSMCE4A |
non-SMC element 4 homolog A (S. cerevisiae) |
10 |
-123706592 |
NM_017615 |
54780 |
10q26.13 |
Hs.258798 |
8 |
|
|
1555694_a_at |
-0.296 |
5.706 |
-2.928 |
1.026e-02 |
0.417 |
-2.578 |
KCNIP3 |
Kv channel interacting protein 3, calsenilin |
2 |
95326798, 95376494 |
AF367022 |
30818 |
2q21.1 |
Hs.437376 |
43 |
negative regulation of transcription from RNA polymerase II promoter DNA binding transcription corepressor activity voltage-gated ion channel activity potassium channel activity calcium ion binding nucleus cytoplasm endoplasmic reticulum Golgi apparatus cytosol plasma membrane ion transport potassium ion transport apoptosis signal transduction behavior protein C-terminus binding specific transcriptional repressor activity sensory perception of pain potassium ion binding regulation of neuron apoptosis regulation of transcription response to pain calcium-dependent protein binding |
|
232568_at |
MGC24103 |
hypothetical MGC24103 |
9 |
|
AU145658 |
158295 |
9p22.3 |
Hs.664877 |
2 |
|
|
214254_at |
MAGEA4 |
melanoma antigen family A, 4 |
X |
150832016, 150835364, 150836052, 150837415 |
AW438674 |
4103 |
Xq28 |
Hs.37107 |
24 |
molecular_function protein binding cellular_component biological_process |
|
230852_at |
STAC3 |
SH3 and cysteine rich domain 3 |
12 |
-55923508 |
AW663959 |
246329 |
12q13.3 |
Hs.417595 |
4 |
intracellular signaling cascade zinc ion binding diacylglycerol binding identical protein binding metal ion binding |
|
223248_at |
-0.464 |
6.573 |
-2.875 |
1.145e-02 |
0.426 |
-2.671 |
HSDL1 |
hydroxysteroid dehydrogenase like 1 |
16 |
-82713244 |
AK025626 |
83693 |
16q23.3 |
Hs.555992 |
8 |
protein binding metabolic process oxidoreductase activity |
|
219209_at |
IFIH1 |
interferon induced with helicase C domain 1 |
2 |
-162831834 |
NM_022168 |
64135 |
2q24 |
Hs.163173 |
36 |
nucleotide binding DNA binding RNA binding helicase activity protein binding ATP binding intracellular nucleus cytoplasm response to virus hydrolase activity regulation of apoptosis interspecies interaction between organisms innate immune response |
RIG-I-like receptor signaling pathway |
203795_s_at |
BCL7A |
B-cell CLL/lymphoma 7A |
12 |
120944243 |
NM_020993 |
605 |
12q24.13 |
Hs.530970 |
9 |
molecular_function cellular_component negative regulation of transcription |
|
227074_at |
LOC100131564 |
hypothetical protein LOC100131564 |
1 |
|
AA524669 |
100131564 |
1p22.1 |
Hs.648647 |
|
|
|
1559206_at |
PSEN1 |
presenilin 1 |
14 |
72672895 |
BC002708 |
5663 |
14q24.3 |
Hs.3260 |
386 |
kinetochore endopeptidase activity membrane fraction integral to nuclear inner membrane nuclear outer membrane mitochondrion endoplasmic reticulum Golgi apparatus integral to plasma membrane membrane protein ectodomain proteolysis apoptosis anti-apoptosis chromosome segregation Notch receptor processing intracellular signaling cascade beta-catenin binding cell death peptidase activity cell surface membrane cell-cell adhesion protein processing PDZ domain binding endoplasmic reticulum calcium ion homeostasis regulation of phosphorylation amyloid precursor protein catabolic process positive regulation of catalytic activity |
Wnt signaling pathway Notch signaling pathway Neurotrophin signaling pathway Alzheimer's disease |
207186_s_at |
BPTF |
bromodomain PHD finger transcription factor |
17 |
63252241 |
NM_004459 |
2186 |
17q24.3 |
Hs.444200 |
22 |
negative regulation of transcription from RNA polymerase II promoter nucleus cytoplasm chromatin remodeling brain development DNA-dependent ATPase activity transcription factor binding zinc ion binding transcription regulator activity positive regulation of gene-specific transcription sequence-specific DNA binding sequence-specific DNA binding regulation of transcription metal ion binding |
|
209497_s_at |
-0.307 |
6.262 |
-2.153 |
4.774e-02 |
0.586 |
-3.866 |
RBM4B |
RNA binding motif protein 4B |
11 |
-66189045 |
BC003503 |
83759 |
11q13 |
Hs.618713 |
8 |
nucleotide binding RNA binding nucleus nucleolus mRNA processing zinc ion binding RNA splicing metal ion binding |
|
214002_at |
MYL6 |
myosin, light chain 6, alkali, smooth muscle and non-muscle |
12 |
54838366 |
AA419227 |
4637 |
12q13.2 |
Hs.632717 |
12 |
motor activity calcium ion binding skeletal muscle tissue development structural constituent of muscle unconventional myosin complex muscle filament sliding actin-dependent ATPase activity |
Vascular smooth muscle contraction |
231885_at |
ZNF451 |
zinc finger protein 451 |
6 |
57062786 |
AB051489 |
26036 |
6p12.1-p11.2 |
Hs.485628 Hs.705485 |
13 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
227566_at |
0.240 |
3.580 |
2.436 |
2.759e-02 |
0.526 |
-3.412 |
NTM |
neurotrimin |
11 |
130745580, 131285921, 131285921, 131285921 |
AW085558 |
50863 |
11q25 |
Hs.504352 |
9 |
protein binding plasma membrane cell adhesion neuron recognition anchored to membrane |
|
205005_s_at |
NMT2 |
N-myristoyltransferase 2 |
10 |
-15187776 |
AW293531 |
9397 |
10p13 |
Hs.60339 |
35 |
glycylpeptide N-tetradecanoyltransferase activity cytoplasm Golgi apparatus N-terminal protein myristoylation acyltransferase activity protein lipoylation transferase activity |
|
206356_s_at |
0.636 |
5.119 |
2.904 |
1.077e-02 |
0.421 |
-2.619 |
GNAL |
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
18 |
11679135, 11741561 |
NM_002071 |
2774 |
18p11.22-p11.21 |
Hs.136295 |
16 |
nucleotide binding GTPase activity signal transducer activity GTP binding signal transduction G-protein coupled receptor protein signaling pathway guanyl nucleotide binding |
Calcium signaling pathway Olfactory transduction |
1566775_at |
DNAH1 |
dynein, axonemal, heavy chain 1 |
3 |
52325374 |
AK093347 |
25981 |
3p21.1 |
Hs.655469 |
7 |
nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme |
Huntington's disease |
240033_at |
-0.411 |
6.080 |
-2.607 |
1.967e-02 |
0.491 |
-3.128 |
PLG |
plasminogen |
6 |
161043263 |
BF447999 |
5340 |
6q26 |
Hs.143436 |
198 |
serine-type endopeptidase activity calcium ion binding extracellular region extracellular region extracellular space proteolysis induction of apoptosis blood coagulation peptidase activity negative regulation of cell proliferation negative regulation of angiogenesis apolipoprotein binding negative regulation of blood vessel endothelial cell migration tissue remodeling negative regulation of fibrinolysis positive regulation of fibrinolysis |
Neuroactive ligand-receptor interaction Complement and coagulation cascades |
203020_at |
RABGAP1L |
RAB GTPase activating protein 1-like |
1 |
172395256, 173111306 |
NM_014857 |
9910 |
1q24 |
Hs.585378 |
9 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
214208_at |
KLHL35 |
kelch-like 35 (Drosophila) |
11 |
-74811085 |
BF448703 |
283212 |
11q13.4 |
Hs.292451 |
2 |
|
|
226206_at |
MAFK |
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) |
7 |
1536893 |
BG231691 |
7975 |
7p22.3 |
Hs.520612 |
14 |
transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent nervous system development sequence-specific DNA binding |
|
210762_s_at |
DLC1 |
deleted in liver cancer 1 |
8 |
-13116452, -12985242, -12985242 |
AF026219 |
10395 |
8p22 |
Hs.134296 |
48 |
neural tube closure heart morphogenesis GTPase activator activity protein binding intracellular nucleus cytoplasm caveola focal adhesion induction of apoptosis activation of caspase activity signal transduction negative regulation of cell proliferation negative regulation of cell proliferation regulation of cell shape hindbrain morphogenesis negative regulation of cell migration negative regulation of cell migration Rac GTPase activator activity forebrain development regulation of actin cytoskeleton organization negative regulation of Rho protein signal transduction positive regulation of protein amino acid dephosphorylation SH2 domain binding focal adhesion formation negative regulation of stress fiber formation |
|
219977_at |
AIPL1 |
aryl hydrocarbon receptor interacting protein-like 1 |
17 |
-6267782 |
NM_014336 |
23746 |
17p13.1 |
Hs.279887 |
18 |
farnesylated protein binding binding nucleus cytoplasm visual perception protein farnesylation response to stimulus unfolded protein binding |
|
202717_s_at |
CDC16 |
cell division cycle 16 homolog (S. cerevisiae) |
13 |
114018463 |
NM_003903 |
8881 |
13q34 |
Hs.374127 |
32 |
binding nucleoplasm cytoplasm centrosome cytosol spindle microtubule cell cycle regulation of mitosis cell proliferation modification-dependent protein catabolic process anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Cell cycle Ubiquitin mediated proteolysis |
201994_at |
MORF4L2 |
mortality factor 4 like 2 |
X |
-102817083, -102817083 |
NM_012286 |
9643 |
Xq22 |
Hs.326387 Hs.441076 Hs.597035 |
19 |
regulation of cell growth molecular_function protein binding nucleus nucleolus DNA repair response to DNA damage stimulus chromatin modification regulation of transcription |
|
225211_at |
PVRL1 |
poliovirus receptor-related 1 (herpesvirus entry mediator C) |
11 |
-119050308, -119036912, -119014017 |
AW139723 |
5818 |
11q23.3 |
Hs.334846 |
42 |
extracellular region plasma membrane cell-cell adherens junction immune response homophilic cell adhesion heterophilic cell adhesion coreceptor activity integral to membrane protein homodimerization activity interspecies interaction between organisms entry of virus into host cell cell adhesion molecule binding |
Cell adhesion molecules (CAMs) Adherens junction |
231157_at |
0.357 |
5.922 |
2.214 |
4.247e-02 |
0.575 |
-3.770 |
TTLL11 |
tubulin tyrosine ligase-like family, member 11 |
9 |
-123791010, -123624025 |
BE856668 |
158135 |
9q33.2 |
Hs.640663 Hs.644262 |
5 |
tubulin-tyrosine ligase activity cilium microtubule basal body protein modification process ligase activity |
|
231539_at |
C3orf67 |
chromosome 3 open reading frame 67 |
3 |
-58702776 |
AW204126 |
200844 |
3p14.2 |
Hs.368434 |
1 |
|
|
1569194_at |
ZNF789 |
zinc finger protein 789 |
7 |
98908450, 98908450 |
AL708039 |
285989 |
7q22.1 |
Hs.440384 |
4 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
1555505_a_at |
TYR |
tyrosinase (oculocutaneous albinism IA) |
11 |
88550687 |
BC027179 |
7299 |
11q14-q21 |
Hs.503555 |
121 |
monooxygenase activity monophenol monooxygenase activity copper ion binding protein binding cytoplasm lysosome Golgi-associated vesicle melanin biosynthetic process from tyrosine eye pigment biosynthetic process visual perception membrane integral to membrane melanosome protein homodimerization activity metal ion binding protein heterodimerization activity perinuclear region of cytoplasm oxidation reduction |
Tyrosine metabolism Riboflavin metabolism Isoquinoline alkaloid biosynthesis Betalain biosynthesis Biosynthesis of alkaloids derived from shikimate pathway Metabolic pathways Melanogenesis |
235022_at |
C18orf19 |
chromosome 18 open reading frame 19 |
18 |
-13653345 |
BE326738 |
125228 |
18p11.21 |
Hs.13034 |
3 |
membrane integral to membrane |
|
222879_s_at |
-0.254 |
4.820 |
-2.329 |
3.406e-02 |
0.553 |
-3.587 |
POLH |
polymerase (DNA directed), eta |
6 |
43651855 |
AF158185 |
5429 |
6p21.1 |
Hs.655467 |
65 |
magnesium ion binding DNA synthesis during DNA repair damaged DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm nucleolus cytoplasm regulation of DNA repair pyrimidine dimer repair postreplication repair response to DNA damage stimulus response to UV-C transferase activity nucleotidyltransferase activity |
|
237407_at |
HS1BP3 |
HCLS1 binding protein 3 |
2 |
-20681044 |
BF197459 |
64342 |
2p24.1 |
Hs.531785 |
7 |
protein binding cell communication phosphoinositide binding |
|
210879_s_at |
0.354 |
6.423 |
2.974 |
9.351e-03 |
0.401 |
-2.499 |
RAB11FIP5 |
RAB11 family interacting protein 5 (class I) |
2 |
-73154017 |
AF334812 |
26056 |
2p13-p12 |
Hs.24557 |
19 |
protein binding cytoplasm mitochondrion mitochondrial outer membrane endosome biological_process protein transport membrane gamma-tubulin binding |
Endocytosis |
1555595_at |
SCRN3 |
secernin 3 |
2 |
174968712 |
BC007344 |
79634 |
2q31.1 |
Hs.470679 |
7 |
|
|
1559481_at |
CHIC1 |
cysteine-rich hydrophobic domain 1 |
X |
72699708 |
AL832095 |
53344 |
Xq13-q21 |
Hs.496323 |
5 |
plasma membrane cytoplasmic vesicle |
|
1554531_at |
TTC12 |
tetratricopeptide repeat domain 12 |
11 |
112690460 |
BC032355 |
54970 |
11q23.2 |
Hs.288772 |
11 |
binding |
|
219952_s_at |
MCOLN1 |
mucolipin 1 |
19 |
7493511 |
NM_020533 |
57192 |
19p13.3-p13.2 |
Hs.631858 |
37 |
cation channel activity calcium ion binding lysosome endosome plasma membrane integral to plasma membrane cation transport calcium ion transport |
|
232457_at |
LIMCH1 |
LIM and calponin homology domains 1 |
4 |
41057560, 41309675 |
AU147704 |
22998 |
4p13 |
Hs.335163 |
10 |
actin binding zinc ion binding actomyosin structure organization metal ion binding |
|
218695_at |
0.480 |
6.821 |
2.477 |
2.546e-02 |
0.516 |
-3.344 |
EXOSC4 |
exosome component 4 |
8 |
145205509 |
NM_019037 |
54512 |
8q24.3 |
Hs.632041 |
16 |
3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity |
RNA degradation |
1553561_at |
TAS2R50 |
taste receptor, type 2, member 50 |
12 |
-11029778 |
NM_176890 |
259296 |
12p13.2 |
Hs.688194 |
13 |
receptor activity G-protein coupled receptor activity signal transduction G-protein coupled receptor protein signaling pathway membrane integral to membrane response to stimulus sensory perception of taste |
Taste transduction |
241834_at |
IPW |
imprinted in Prader-Willi syndrome (non-protein coding) |
15 |
22912784 |
AW299520 |
3653 |
15q11-q12 |
Hs.555970 |
3 |
|
|
209144_s_at |
CBFA2T2 |
core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
20 |
31541588, 31613831 |
AI810484 |
9139 |
20q11 |
Hs.153934 |
19 |
transcription factor activity transcription corepressor activity protein binding nucleus zinc ion binding epithelial cell differentiation negative regulation of transcription, DNA-dependent metal ion binding |
|
235405_at |
GSTA4 |
glutathione S-transferase alpha 4 |
6 |
-52950705 |
N79662 |
2941 |
6p12.1 |
Hs.485557 |
34 |
glutathione transferase activity cytoplasm metabolic process transferase activity |
Glutathione metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 |
32091_at |
SLC25A44 |
solute carrier family 25, member 44 |
1 |
154430353 |
AB007915 |
9673 |
1q22 |
Hs.532375 |
6 |
transporter activity binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
235855_at |
COX15 |
COX15 homolog, cytochrome c oxidase assembly protein (yeast) |
10 |
-101458494 |
AA535888 |
1355 |
10q24 |
Hs.28326 |
9 |
catalytic activity cytochrome-c oxidase activity mitochondrial respiratory chain mitochondrial electron transport, cytochrome c to oxygen protein complex assembly heme a biosynthetic process respiratory gaseous exchange respiratory chain complex IV assembly membrane integral to membrane mitochondrial part cellular respiration oxidation reduction |
Oxidative phosphorylation Porphyrin and chlorophyll metabolism Metabolic pathways |
232745_x_at |
SPEF2 |
sperm flagellar 2 |
5 |
35653745, 35653745 |
AK026817 |
79925 |
5p13.2 |
Hs.298863 |
10 |
protein dimerization activity |
|
226085_at |
CBX5 |
chromobox homolog 5 (HP1 alpha homolog, Drosophila) |
12 |
-52910996, -52910996, -52910996 |
AA181060 |
23468 |
12q13.13 |
Hs.349283 |
65 |
kinetochore chromatin chromatin binding nucleus nuclear envelope nucleolus cytoplasm chromatin assembly or disassembly chromocenter negative regulation of transcription general transcriptional repressor activity PML body enzyme binding nuclear centromeric heterochromatin |
|
203614_at |
UTP14C |
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) |
13 |
51496827 |
NM_021645 |
9724 |
13q14.2 |
Hs.512963 |
7 |
nucleus nucleolus rRNA processing meiosis multicellular organismal development spermatogenesis cell differentiation small-subunit processome |
|
209941_at |
RIPK1 |
receptor (TNFRSF)-interacting serine-threonine kinase 1 |
6 |
3022056 |
U50062 |
8737 |
6p25.2 |
Hs.519842 |
83 |
nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity death receptor binding protein binding ATP binding cytoplasm mitochondrion cytosol induction of apoptosis signal transduction activation of JUN kinase activity activation of pro-apoptotic gene products positive regulation of necrotic cell death transferase activity death-inducing signaling complex tumor necrosis factor-mediated signaling pathway response to tumor necrosis factor positive regulation of I-kappaB kinase/NF-kappaB cascade receptor complex positive regulation of anti-apoptosis protein amino acid autophosphorylation positive regulation of NF-kappaB transcription factor activity induction of necroptosis by extracellular signals death domain binding regulation of oxygen and reactive oxygen species metabolic process |
Apoptosis Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway |
1564837_at |
LOC151760 |
hypothetical LOC151760 |
3 |
|
BC038577 |
151760 |
3q13.13 |
Hs.124136 |
1 |
|
|
221482_s_at |
ARPP19 |
cAMP-regulated phosphoprotein, 19kDa |
15 |
-50626723 |
BC003418 |
10776 |
15q21.2 |
Hs.512908 |
10 |
receptor binding cytoplasm potassium channel regulator activity positive regulation of gluconeogenesis positive regulation of glucose import |
|
224570_s_at |
IRF2BP2 |
interferon regulatory factor 2 binding protein 2 |
1 |
-232806637 |
AA166696 |
359948 |
1q42.3 |
Hs.693837 |
5 |
nucleus regulation of transcription |
|
236666_s_at |
LOC390205 |
leucine rich repeat containing 10-like |
11 |
61032847 |
AA923289 |
390205 |
11q12.2 |
Hs.441122 |
1 |
protein binding |
|
1553534_at |
-0.221 |
4.010 |
-2.540 |
2.245e-02 |
0.500 |
-3.239 |
NLRP10 |
NLR family, pyrin domain containing 10 |
11 |
-7937731 |
NM_176821 |
338322 |
11p15.4 |
Hs.449636 |
6 |
nucleotide binding protein binding ATP binding |
|
210512_s_at |
-0.905 |
10.577 |
-2.271 |
3.811e-02 |
0.565 |
-3.680 |
VEGFA |
vascular endothelial growth factor A |
6 |
43845930 |
AF022375 |
7422 |
6p12 |
Hs.73793 |
1447 |
angiogenesis vasculogenesis response to hypoxia positive regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation fibronectin binding positive regulation of leukocyte migration cytokine activity platelet-derived growth factor receptor binding extracellular region extracellular region proteinaceous extracellular matrix extracellular space multicellular organismal development nervous system development growth factor activity heparin binding regulation of cell shape cell surface membrane positive regulation of vascular endothelial growth factor receptor signaling pathway platelet alpha granule lumen protein homodimerization activity negative regulation of apoptosis vascular endothelial growth factor receptor 1 binding vascular endothelial growth factor receptor 2 binding cell surface binding positive regulation of blood vessel endothelial cell migration platelet-derived growth factor receptor signaling pathway extracellular matrix binding induction of positive chemotaxis |
Cytokine-cytokine receptor interaction mTOR signaling pathway VEGF signaling pathway Focal adhesion Pathways in cancer Renal cell carcinoma Pancreatic cancer Bladder cancer |
201876_at |
0.456 |
7.307 |
2.168 |
4.637e-02 |
0.582 |
-3.842 |
PON2 |
paraoxonase 2 |
7 |
-94872109 |
NM_000305 |
5445 |
7q21.3 |
Hs.719159 |
112 |
aryldialkylphosphatase activity arylesterase activity extracellular region plasma membrane hydrolase activity aromatic compound catabolic process identical protein binding |
gamma-Hexachlorocyclohexane degradation Bisphenol A degradation Metabolic pathways |
209653_at |
KPNA4 |
karyopherin alpha 4 (importin alpha 3) |
3 |
-161700655 |
U93240 |
3840 |
3q25.33 |
Hs.715552 |
53 |
protein binding nucleus nuclear pore cytoplasm NLS-bearing substrate import into nucleus intracellular protein transport protein transporter activity |
|
205459_s_at |
NPAS2 |
neuronal PAS domain protein 2 |
2 |
100803044 |
NM_002518 |
4862 |
2q11.2 |
Hs.156832 Hs.705895 |
23 |
transcription factor activity signal transducer activity nucleus transcription factor complex regulation of transcription, DNA-dependent signal transduction central nervous system development circadian sleep/wake cycle locomotor rhythm positive regulation of transcription from RNA polymerase II promoter rhythmic process Hsp90 protein binding |
Circadian rhythm - mammal |
230115_at |
0.348 |
6.442 |
2.298 |
3.613e-02 |
0.558 |
-3.636 |
DKFZp779M0652 |
hypothetical DKFZp779M0652 |
11 |
45749558 |
BE348376 |
374387 |
11p11.2 |
Hs.632142 |
1 |
|
|
212007_at |
0.433 |
7.848 |
2.733 |
1.526e-02 |
0.457 |
-2.914 |
UBXN4 |
UBX domain protein 4 |
2 |
136215658 |
AI927512 |
23190 |
2q21.3 |
Hs.591242 |
12 |
protein binding nucleus nuclear envelope endoplasmic reticulum response to unfolded protein membrane integral to membrane |
|
218689_at |
FANCF |
Fanconi anemia, complementation group F |
11 |
-22600654 |
NM_022725 |
2188 |
11p15 |
Hs.713574 |
27 |
molecular_function protein binding cellular_component nucleus DNA repair response to DNA damage stimulus biological_process |
|
1553314_a_at |
KIF19 |
kinesin family member 19 |
17 |
69833945 |
NM_153209 |
124602 |
17q25.1 |
Hs.372773 |
6 |
nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement |
|
220536_at |
C14orf115 |
chromosome 14 open reading frame 115 |
14 |
73884918 |
NM_018228 |
55237 |
14q24.3 |
Hs.578167 |
4 |
DNA binding transposase activity transposition, DNA-mediated |
|
205953_at |
LRIG2 |
leucine-rich repeats and immunoglobulin-like domains 2 |
1 |
113417353 |
NM_014813 |
9860 |
1p13.1 |
Hs.448972 Hs.696605 |
7 |
protein binding cytoplasm plasma membrane integral to membrane |
|
207862_at |
UPK2 |
uroplakin 2 |
11 |
118332235 |
NM_006760 |
7379 |
11q23 |
Hs.710330 |
14 |
plasma membrane integral to plasma membrane multicellular organismal development membrane organization integral to endoplasmic reticulum membrane epithelial cell differentiation |
|
231509_at |
-0.263 |
4.313 |
-2.257 |
3.911e-02 |
0.567 |
-3.702 |
C7orf16 |
chromosome 7 open reading frame 16 |
7 |
31693323 |
AW614524 |
10842 |
7p15 |
Hs.227011 |
8 |
protein serine/threonine phosphatase inhibitor activity soluble fraction protein amino acid phosphorylation signal transduction protein kinase cascade central nervous system development behavior |
Long-term depression |
1562738_a_at |
0.264 |
2.781 |
2.397 |
2.978e-02 |
0.536 |
-3.475 |
LOC100130855 |
hypothetical protein LOC100130855 |
15 |
|
AK093077 |
100130855 |
15q22.31 |
Hs.667198 |
2 |
|
|
225630_at |
EEPD1 |
endonuclease/exonuclease/phosphatase family domain containing 1 |
7 |
36159360 |
AB051493 |
80820 |
7p14.2 |
Hs.487994 Hs.670591 |
4 |
DNA binding intracellular DNA repair |
|
210939_s_at |
GRM1 |
glutamate receptor, metabotropic 1 |
6 |
146390474 |
L76631 |
2911 |
6q24 |
Hs.32945 |
51 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway synaptic transmission glutamate receptor activity |
Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction Long-term potentiation Long-term depression |
232625_at |
TLN2 |
talin 2 |
15 |
60726801 |
AA719572 |
83660 |
15q15-q21 |
Hs.569438 Hs.610975 |
17 |
ruffle actin binding structural constituent of cytoskeleton protein binding cytoplasm plasma membrane cell-cell junction focal adhesion cytoskeletal anchoring at plasma membrane cell-cell junction assembly cell adhesion actin cytoskeleton synapse |
Focal adhesion |
238947_at |
MFSD3 |
major facilitator superfamily domain containing 3 |
8 |
145705359 |
BE048524 |
113655 |
8q24.3 |
Hs.7678 |
3 |
transport membrane integral to membrane |
|
222223_s_at |
IL1F5 |
interleukin 1 family, member 5 (delta) |
2 |
113532685, 113533155 |
AF216693 |
26525 |
2q14 |
Hs.516301 |
28 |
cytokine activity interleukin-1 receptor antagonist activity extracellular region extracellular space immune response |
|
1553959_a_at |
B3GALT6 |
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 |
1 |
1157491 |
N95564 |
126792 |
1p36.33 |
Hs.284284 |
4 |
Golgi apparatus Golgi medial cisterna glycosaminoglycan biosynthetic process protein amino acid glycosylation UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding galactosylxylosylprotein 3-beta-galactosyltransferase activity |
Chondroitin sulfate biosynthesis Heparan sulfate biosynthesis Metabolic pathways |
202056_at |
KPNA1 |
karyopherin alpha 1 (importin alpha 5) |
3 |
-123623437 |
AW051311 |
3836 |
3q21 |
Hs.161008 |
92 |
regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
238689_at |
GPR110 |
G protein-coupled receptor 110 |
6 |
-47095580, -47075771 |
BG426455 |
266977 |
6p12.3 |
Hs.256897 |
11 |
G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane |
|
217074_at |
SMOX |
spermine oxidase |
20 |
4077449 |
AK025938 |
54498 |
20p13 |
Hs.433337 |
17 |
cytoplasm electron carrier activity oxidoreductase activity spermine catabolic process polyamine oxidase activity oxidation reduction |
|
1555450_a_at |
NARG1L |
NMDA receptor regulated 1-like |
13 |
40783340, 40783340, 40783417 |
BC032318 |
79612 |
13q14.11 |
Hs.512914 |
8 |
protein binding nucleus transcription factor complex cytoplasm N-terminal protein amino acid acetylation acetyltransferase activity ribosome binding positive regulation of transcription, DNA-dependent |
|
203055_s_at |
ARHGEF1 |
Rho guanine nucleotide exchange factor (GEF) 1 |
19 |
47079106, 47080285 |
NM_004706 |
9138 |
19q13.13 |
Hs.631550 |
29 |
guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding intracellular cytoplasm cytosol plasma membrane plasma membrane cell proliferation regulation of Rho protein signal transduction |
Vascular smooth muscle contraction Regulation of actin cytoskeleton |
229748_x_at |
LOC100132288 |
hypothetical protein LOC100132288 |
21 |
-103279, -493625 |
AI380156 |
100132288 |
21p11.2 |
Hs.487562 |
7 |
|
|
214743_at |
CUX1 |
cut-like homeobox 1 |
7 |
101246011, 101246022, 101247601 |
BE046521 |
1523 |
7q22.1 |
Hs.654389 |
53 |
negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription from RNA polymerase II promoter DNA binding chromatin binding transcription factor activity RNA polymerase II transcription factor activity nucleus Golgi apparatus transport intra-Golgi vesicle-mediated transport multicellular organismal development membrane integral to membrane transcription repressor activity integral to Golgi membrane lung development auditory receptor cell differentiation sequence-specific DNA binding |
|
1554253_a_at |
LASS3 |
LAG1 homolog, ceramide synthase 3 |
15 |
-98758122 |
BC028703 |
204219 |
15q26.3 |
Hs.662371 |
3 |
transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent lipid biosynthetic process membrane integral to membrane sphingolipid biosynthetic process sequence-specific DNA binding sphingosine N-acyltransferase activity |
|
220485_s_at |
SIRPG |
signal-regulatory protein gamma |
20 |
-1557797 |
NM_018556 |
55423 |
20p13 |
Hs.590883 |
11 |
protein binding plasma membrane cell adhesion intracellular signaling cascade cell-cell signaling positive regulation of cell proliferation negative regulation of cell proliferation integral to membrane positive regulation of cell-cell adhesion positive regulation of T cell activation |
|
237894_at |
C3orf22 |
chromosome 3 open reading frame 22 |
3 |
-127751208 |
AA437300 |
152065 |
3q21.3 |
Hs.178210 |
3 |
|
|
235848_x_at |
ATL2 |
atlastin GTPase 2 |
2 |
-38375534 |
N35250 |
64225 |
2p22.2-p22.1 |
Hs.594950 |
8 |
nucleotide binding GTPase activity GTP binding membrane integral to membrane |
|
1556351_at |
HCN1 |
hyperpolarization activated cyclic nucleotide-gated potassium channel 1 |
5 |
-45295108 |
BM682352 |
348980 |
5p12 |
Hs.650434 |
17 |
nucleotide binding voltage-gated ion channel activity voltage-gated potassium channel activity sodium channel activity protein binding ion transport potassium ion transport sodium ion transport membrane integral to membrane axon dendrite cAMP binding potassium ion binding sodium ion binding apical protein localization |
|
209650_s_at |
TBC1D22A |
TBC1 domain family, member 22A |
22 |
45537212 |
BC001292 |
25771 |
22q13.3 |
Hs.435044 |
9 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
221531_at |
WDR61 |
WD repeat domain 61 |
15 |
-76362632 |
AF309553 |
80349 |
15q25.1 |
Hs.513055 |
6 |
|
RNA degradation |
208473_s_at |
-0.368 |
4.033 |
-2.301 |
3.591e-02 |
0.557 |
-3.631 |
GP2 |
glycoprotein 2 (zymogen granule membrane) |
16 |
-20229311 |
NM_016295 |
2813 |
16p12 |
Hs.53985 |
16 |
extracellular region cytoplasm plasma membrane anchored to membrane |
|
212468_at |
SPAG9 |
sperm associated antigen 9 |
17 |
-46394534 |
AK023512 |
9043 |
17q21.33 |
Hs.463439 |
22 |
acrosomal vesicle protein binding cytoplasm spermatogenesis integral to membrane positive regulation of cell migration perinuclear region of cytoplasm |
|
200736_s_at |
GPX1 |
glutathione peroxidase 1 |
3 |
-49369612 |
NM_000581 |
2876 |
3p21.3 |
Hs.76686 |
126 |
temperature homeostasis release of cytochrome c from mitochondria endothelial cell development negative regulation of inflammatory response to antigenic stimulus glutathione peroxidase activity glutathione peroxidase activity cytoplasm mitochondrion cytosol lipid metabolic process triglyceride metabolic process glutathione metabolic process anti-apoptosis induction of apoptosis sensory perception of sound selenium binding proteasome inhibitor activity induction of apoptosis by oxidative stress response to xenobiotic stimulus response to symbiotic bacterium response to wounding response to toxin UV protection response to selenium ion response to gamma radiation myotube differentiation oxidoreductase activity SH3 domain binding protein amino acid oxidation response to hydroperoxide regulation of mammary gland epithelial cell proliferation regulation of gene expression, epigenetic vasodilation response to hydrogen peroxide hydrogen peroxide catabolic process negative regulation of caspase activity glutathione binding skeletal muscle regeneration regulation of neuron apoptosis blood vessel endothelial cell migration fat cell differentiation myoblast proliferation interaction with symbiont positive regulation of protein kinase B signaling cascade oxidation reduction heart contraction angiogenesis involved in wound healing |
Glutathione metabolism Arachidonic acid metabolism Amyotrophic lateral sclerosis (ALS) Huntington's disease |
202042_at |
HARS |
histidyl-tRNA synthetase |
5 |
-140033673 |
NM_002109 |
3035 |
5q31.3 |
Hs.528050 |
20 |
nucleotide binding histidine-tRNA ligase activity ATP binding cytoplasm histidyl-tRNA aminoacylation ligase activity |
Aminoacyl-tRNA biosynthesis |
203833_s_at |
-0.337 |
5.474 |
-2.658 |
1.773e-02 |
0.473 |
-3.040 |
TGOLN2 |
trans-golgi network protein 2 |
2 |
-85398656 |
BF061845 |
10618 |
2p11.2 |
Hs.593382 |
14 |
protein binding nucleus nucleolus cytoplasm Golgi apparatus trans-Golgi network plasma membrane integral to membrane transport vesicle |
|
210165_at |
DNASE1 |
deoxyribonuclease I |
16 |
3642940 |
M55983 |
1773 |
16p13.3 |
Hs.629638 |
48 |
actin binding endonuclease activity deoxyribonuclease I activity deoxyribonuclease activity calcium ion binding protein binding extracellular region nucleus nuclear envelope DNA catabolic process apoptosis hydrolase activity |
|
215034_s_at |
0.505 |
6.910 |
3.520 |
3.038e-03 |
0.300 |
-1.542 |
TM4SF1 |
transmembrane 4 L six family member 1 |
3 |
-150569494 |
AI189753 |
4071 |
3q21-q25 |
Hs.715499 |
16 |
molecular_function integral to plasma membrane biological_process membrane |
|
1558306_at |
-0.327 |
3.086 |
-3.346 |
4.349e-03 |
0.328 |
-1.848 |
THADA |
thyroid adenoma associated |
2 |
-43311478, -43311478 |
AL832141 |
63892 |
2p21 |
Hs.369592 |
17 |
binding |
|
1552256_a_at |
SCARB1 |
scavenger receptor class B, member 1 |
12 |
-123828126 |
NM_005505 |
949 |
12q24.31 |
Hs.709216 |
127 |
phosphatidylserine binding lipopolysaccharide receptor activity receptor activity transporter activity phosphatidylinositol binding plasma membrane caveola cell adhesion positive regulation of endothelial cell migration positive regulation of cholesterol storage lipopolysaccharide transport integral to membrane low-density lipoprotein binding detection of lipopolysaccharide cholesterol efflux apolipoprotein A-I binding high-density lipoprotein particle remodeling high-density lipoprotein particle clearance wound healing cholesterol homeostasis recognition of apoptotic cell reverse cholesterol transport interspecies interaction between organisms regulation of phagocytosis positive regulation of nitric-oxide synthase activity adhesion to symbiont triglyceride homeostasis high-density lipoprotein receptor activity cholesterol import |
|
207311_at |
DOC2B |
double C2-like domains, beta |
17 |
633000 |
NM_003585 |
8447 |
17p13.3 |
Hs.648240 |
8 |
transporter activity calcium ion binding calcium-dependent phospholipid binding transport synaptic vesicle membrane |
|
206724_at |
CBX4 |
chromobox homolog 4 (Pc class homolog, Drosophila) |
17 |
-75421549 |
NM_003655 |
8535 |
17q25.3 |
Hs.714363 |
25 |
chromatin chromatin binding transcription corepressor activity nucleus chromatin assembly or disassembly anti-apoptosis negative regulation of transcription chromatin modification enzyme binding modification-dependent protein catabolic process |
|
218078_s_at |
ZDHHC3 |
zinc finger, DHHC-type containing 3 |
3 |
-44931757 |
NM_016598 |
51304 |
3p21.31 |
Hs.61430 |
8 |
Golgi apparatus zinc ion binding acyltransferase activity membrane integral to membrane transferase activity metal ion binding |
|
212639_x_at |
0.644 |
10.322 |
2.677 |
1.707e-02 |
0.470 |
-3.008 |
TUBA1B |
tubulin, alpha 1b |
12 |
-47807832 |
AL581768 |
10376 |
12q13.12 |
Hs.524390 Hs.719075 |
42 |
nucleotide binding microtubule cytoskeleton organization GTPase activity structural constituent of cytoskeleton protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
210094_s_at |
PARD3 |
par-3 partitioning defective 3 homolog (C. elegans) |
10 |
-34440102 |
AF196186 |
56288 |
10p11.21 |
Hs.131489 |
40 |
protein binding cytoplasm plasma membrane tight junction tight junction cell cortex protein complex assembly cell cycle establishment or maintenance of cell polarity activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway axonogenesis asymmetric cell division cell junction |
Chemokine signaling pathway Neuroactive ligand-receptor interaction Endocytosis Adherens junction Tight junction |
204157_s_at |
QSK |
serine/threonine-protein kinase QSK |
11 |
-116219327 |
NM_025164 |
23387 |
11q23.3 |
Hs.167451 |
14 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
207494_s_at |
ZNF76 |
zinc finger protein 76 (expressed in testis) |
6 |
35335487 |
NM_003427 |
7629 |
6p21.3-p21.2 |
Hs.388024 |
9 |
DNA binding intracellular nucleus regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase III promoter zinc ion binding regulation of transcription metal ion binding |
|
206080_at |
PLCH2 |
phospholipase C, eta 2 |
1 |
2397613 |
NM_014638 |
9651 |
1p36.32 |
Hs.170156 |
7 |
molecular_function phosphoinositide phospholipase C activity signal transducer activity calcium ion binding cellular_component cytoplasm plasma membrane intracellular signaling cascade biological_process lipid catabolic process hydrolase activity |
|
240444_x_at |
CLIP1 |
CAP-GLY domain containing linker protein 1 |
12 |
-121321933 |
AA868722 |
6249 |
12q24.3 |
Hs.524809 |
37 |
kinetochore nucleic acid binding protein binding cytoplasm endosome microtubule intermediate filament mitosis microtubule binding zinc ion binding protein homodimerization activity metal ion binding |
|
209199_s_at |
MEF2C |
myocyte enhancer factor 2C |
5 |
-88049814, -88049814 |
N22468 |
4208 |
5q14 |
Hs.653394 |
56 |
transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development negative regulation of specific transcription from RNA polymerase II promoter nuclear speck cell differentiation sequence-specific DNA binding positive regulation of survival gene product expression |
MAPK signaling pathway |
222558_at |
RPRD1A |
regulation of nuclear pre-mRNA domain containing 1A |
18 |
-31823789 |
T79568 |
55197 |
18q12.2 |
Hs.464912 |
3 |
|
|
217940_s_at |
0.477 |
7.691 |
3.583 |
2.664e-03 |
0.290 |
-1.431 |
CARKD |
carbohydrate kinase domain containing |
13 |
110066008 |
NM_018210 |
55739 |
13q34 |
Hs.408324 |
5 |
molecular_function cellular_component biological_process |
|
202743_at |
-0.730 |
6.644 |
-2.779 |
1.389e-02 |
0.442 |
-2.835 |
PIK3R3 |
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
1 |
-46278398, -46278398 |
BE622627 |
8503 |
1p34.1 |
Hs.655387 |
16 |
protein binding phosphoinositide 3-kinase complex insulin receptor signaling pathway 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase regulator activity |
ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer |
236098_at |
hCG_1643808 |
hypothetical protein LOC100130933 |
17 |
71154240 |
AA429598 |
100130933 |
|
Hs.662541 |
2 |
|
|
233496_s_at |
CFL2 |
cofilin 2 (muscle) |
14 |
-34249338, -34249338, -34249338 |
AV726166 |
1073 |
14q12 |
Hs.180141 |
20 |
actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix |
Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
230380_at |
0.515 |
4.434 |
2.721 |
1.561e-02 |
0.459 |
-2.933 |
THAP2 |
THAP domain containing, apoptosis associated protein 2 |
12 |
70344050 |
AW235671 |
83591 |
12q21.1 |
Hs.245798 |
8 |
DNA binding nucleolus zinc ion binding metal ion binding |
|
1554564_a_at |
UNQ1887 |
signal peptide peptidase 3 |
12 |
-119685417 |
BC011943 |
121665 |
12q24.31 |
Hs.507087 Hs.683964 |
12 |
aspartic-type endopeptidase activity peptidase activity membrane integral to membrane |
|
204652_s_at |
NRF1 |
nuclear respiratory factor 1 |
7 |
129038790, 129057154 |
NM_005011 |
4899 |
7q32 |
Hs.654363 |
47 |
DNA binding nucleus generation of precursor metabolites and energy regulation of transcription from RNA polymerase II promoter regulation of transcription |
Huntington's disease |
229203_at |
B4GALNT3 |
beta-1,4-N-acetyl-galactosaminyl transferase 3 |
12 |
439803 |
AI695127 |
283358 |
12p13.33 |
Hs.504416 |
6 |
Golgi apparatus membrane integral to membrane transferase activity Golgi cisterna membrane N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity |
|
1553219_a_at |
-0.262 |
3.713 |
-2.323 |
3.443e-02 |
0.553 |
-3.596 |
AMMECR1 |
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
X |
-109324069 |
NM_015365 |
9949 |
Xq22.3 |
Hs.656243 |
7 |
molecular_function cellular_component biological_process |
|
35147_at |
MCF2L |
MCF.2 cell line derived transforming sequence-like |
13 |
112670757, 112681655 |
AB002360 |
23263 |
13q34 |
Hs.170422 Hs.597691 |
15 |
guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm mitochondrion plasma membrane intracellular signaling cascade regulation of Rho protein signal transduction |
|
238989_at |
C1GALT1C1 |
C1GALT1-specific chaperone 1 |
X |
-119643561 |
BF749723 |
29071 |
Xq24 |
Hs.643920 |
13 |
membrane integral to membrane |
O-Glycan biosynthesis Metabolic pathways |
228082_at |
ASAM |
adipocyte-specific adhesion molecule |
11 |
-122448242 |
BF056275 |
79827 |
11q24.1 |
Hs.591949 Hs.665354 |
8 |
nucleus cytoplasm plasma membrane tight junction integral to membrane cell junction |
|
221951_at |
0.503 |
7.360 |
3.026 |
8.395e-03 |
0.388 |
-2.407 |
TMEM80 |
transmembrane protein 80 |
11 |
685615 |
AI739035 |
283232 |
11p15.5 |
Hs.448664 |
2 |
membrane integral to membrane |
|
1564241_at |
ATP1A4 |
ATPase, Na+/K+ transporting, alpha 4 polypeptide |
1 |
158387975, 158413824 |
AK098076 |
480 |
1q21-q23 |
Hs.662219 |
18 |
nucleotide binding magnesium ion binding sodium:potassium-exchanging ATPase activity ATP binding sodium:potassium-exchanging ATPase complex ATP biosynthetic process potassium ion transport sodium ion transport metabolic process monovalent inorganic cation transmembrane transporter activity ATP hydrolysis coupled proton transport membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances sperm motility regulation of cellular pH potassium ion binding sodium ion binding |
Cardiac muscle contraction |
1557866_at |
-0.265 |
4.542 |
-2.731 |
1.532e-02 |
0.457 |
-2.917 |
C9orf117 |
chromosome 9 open reading frame 117 |
9 |
129509091 |
AK094948 |
286207 |
9q34.11 |
Hs.652519 |
2 |
|
|
234633_at |
-0.338 |
3.013 |
-2.925 |
1.032e-02 |
0.418 |
-2.583 |
KRTAP4-11 |
keratin associated protein 4-11 |
17 |
-36526961, 234615 |
AJ406944 |
653240 |
17q21.2 |
Hs.307015 Hs.719695 Hs.719855 |
5 |
keratin filament |
|
201402_at |
ADRBK1 |
adrenergic, beta, receptor kinase 1 |
11 |
66790480 |
NM_001619 |
156 |
11q13.1 |
Hs.83636 |
98 |
nucleotide binding regulation of the force of heart contraction desensitization of G-protein coupled receptor protein signaling pathway negative regulation of the force of heart contraction by chemical signal G-protein coupled receptor kinase activity signal transducer activity protein binding ATP binding soluble fraction cytoplasm signal transduction muscarinic acetylcholine receptor signaling pathway tachykinin receptor signaling pathway heart development membrane transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation positive regulation of catecholamine secretion negative regulation of striated muscle contraction beta-adrenergic receptor kinase activity cardiac muscle contraction |
Chemokine signaling pathway Endocytosis |
218786_at |
NT5DC3 |
5'-nucleotidase domain containing 3 |
12 |
-102690210 |
NM_016575 |
51559 |
12q22-q23.1 |
Hs.48428 |
4 |
magnesium ion binding hydrolase activity |
|
221547_at |
PRPF18 |
PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) |
10 |
13668944 |
BC000794 |
8559 |
10p13 |
Hs.161181 |
6 |
nucleus spliceosomal complex mRNA processing RNA splicing nuclear speck |
|
1555970_at |
FBXO28 |
F-box protein 28 |
1 |
222368413 |
AU154086 |
23219 |
1q42.11 |
Hs.64691 Hs.713992 |
10 |
modification-dependent protein catabolic process |
|
200750_s_at |
0.485 |
9.329 |
2.420 |
2.848e-02 |
0.532 |
-3.438 |
RAN |
RAN, member RAS oncogene family |
12 |
129922569 |
AF054183 |
5901 |
12q24.3 |
Hs.10842 |
132 |
nucleotide binding chromatin chromatin binding transcription coactivator activity GTPase activity GTPase activity protein binding GTP binding nucleus nuclear pore nucleoplasm cytoplasm cytosol DNA metabolic process RNA export from nucleus protein export from nucleus intracellular protein transport nucleocytoplasmic transport mitotic spindle organization mitosis signal transduction androgen receptor signaling pathway melanosome interspecies interaction between organisms positive regulation of transcription, DNA-dependent androgen receptor binding |
|
207446_at |
TLR6 |
toll-like receptor 6 |
4 |
-38504802 |
NM_006068 |
10333 |
4p14 |
Hs.654532 Hs.662185 |
59 |
transmembrane receptor activity plasma membrane plasma membrane integral to plasma membrane inflammatory response signal transduction activation of NF-kappaB-inducing kinase activity lipoprotein binding cytoplasmic vesicle T-helper 1 type immune response defense response to bacterium positive regulation of I-kappaB kinase/NF-kappaB cascade positive regulation of JUN kinase activity innate immune response positive regulation of interleukin-6 biosynthetic process |
Toll-like receptor signaling pathway |
208873_s_at |
REEP5 |
receptor accessory protein 5 |
5 |
-112239979 |
BC000232 |
7905 |
5q22-q23 |
Hs.429608 |
11 |
molecular_function protein binding biological_process membrane integral to membrane |
|
218563_at |
NDUFA3 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
19 |
59297971 |
NM_004542 |
4696 |
19q13.42 |
Hs.198269 |
7 |
mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex I mitochondrial electron transport, NADH to ubiquinone transport NADH dehydrogenase (ubiquinone) activity membrane integral to membrane electron transport chain respiratory chain |
Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease |
206067_s_at |
WT1 |
Wilms tumor 1 |
11 |
-32365900 |
NM_024426 |
7490 |
11p13 |
Hs.591980 |
228 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
219646_at |
0.620 |
6.572 |
3.109 |
7.091e-03 |
0.372 |
-2.264 |
DEF8 |
differentially expressed in FDCP 8 homolog (mouse) |
16 |
88542651, 88542683 |
NM_017702 |
54849 |
16q24.3 |
Hs.62771 |
4 |
protein binding intracellular signaling cascade zinc ion binding diacylglycerol binding metal ion binding |
|
215026_x_at |
SCNN1A |
sodium channel, nonvoltage-gated 1 alpha |
12 |
-6326271, -6326271, -6326271 |
U81961 |
6337 |
12p13 |
Hs.591047 |
80 |
actin binding ion channel activity protein binding membrane fraction plasma membrane ion transport sodium ion transport excretion external side of plasma membrane amiloride-sensitive sodium channel activity integral to membrane apical plasma membrane cortical actin cytoskeleton sodium ion binding sodium channel complex WW domain binding response to stimulus sensory perception of taste |
Taste transduction |
238698_at |
CASK |
calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
X |
-41259132 |
AI659225 |
8573 |
Xp11.4 |
Hs.495984 |
54 |
nucleotide binding guanylate kinase activity protein serine/threonine kinase activity calmodulin binding ATP binding nucleus cytoplasm plasma membrane protein amino acid phosphorylation cell adhesion actin cytoskeleton transferase activity |
Tight junction |
229650_s_at |
0.326 |
6.526 |
3.416 |
3.761e-03 |
0.317 |
-1.724 |
C19orf42 |
chromosome 19 open reading frame 42 |
19 |
-16617958 |
BG538931 |
79086 |
19p13.11 |
Hs.356467 |
1 |
membrane integral to membrane |
|
203628_at |
IGF1R |
insulin-like growth factor 1 receptor |
15 |
97010283 |
H05812 |
3480 |
15q26.3 |
Hs.643120 Hs.653608 Hs.714012 |
315 |
nucleotide binding receptor activity insulin-like growth factor receptor activity insulin receptor binding ATP binding microsome integral to plasma membrane anti-apoptosis immune response signal transduction brain development positive regulation of cell proliferation insulin receptor signaling pathway organ morphogenesis phosphoinositide 3-kinase cascade membrane transferase activity male sex determination positive regulation of cell migration mammary gland development insulin-like growth factor I binding identical protein binding phosphoinositide 3-kinase binding insulin binding insulin receptor substrate binding positive regulation of DNA replication protein amino acid autophosphorylation insulin-like growth factor receptor signaling pathway phosphoinositide-mediated signaling protein tetramerization |
Endocytosis Focal adhesion Adherens junction Long-term depression Pathways in cancer Colorectal cancer Glioma Prostate cancer Melanoma |
218085_at |
CHMP5 |
chromatin modifying protein 5 |
9 |
33254876 |
NM_015961 |
51510 |
9p13.3 |
Hs.635313 |
14 |
regulation of receptor recycling protein binding nucleus cytoplasm endosome cytosol lysosome organization endosome to lysosome transport protein transport membrane |
Endocytosis |
213009_s_at |
TRIM37 |
tripartite motif-containing 37 |
17 |
-54430342, -54414781 |
AK022701 |
4591 |
17q23.2 |
Hs.579079 Hs.605697 |
23 |
protein binding intracellular cytoplasm peroxisome zinc ion binding metal ion binding |
Ubiquitin mediated proteolysis |
1569121_at |
-0.330 |
5.161 |
-2.664 |
1.752e-02 |
0.473 |
-3.031 |
SLC25A24 |
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
1 |
-108478969, -108478969 |
BC029905 |
29957 |
1p13.3 |
Hs.656870 |
4 |
binding calcium ion binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
222853_at |
FLRT3 |
fibronectin leucine rich transmembrane protein 3 |
20 |
-14252642, -14252642 |
N71923 |
23767 |
20p11 |
Hs.41296 |
9 |
receptor signaling protein activity proteinaceous extracellular matrix integral to plasma membrane cell adhesion biological_process membrane protein binding, bridging |
|
206562_s_at |
0.706 |
6.685 |
3.218 |
5.665e-03 |
0.356 |
-2.073 |
CSNK1A1 |
casein kinase 1, alpha 1 |
5 |
-148855037 |
NM_001892 |
1452 |
5q32 |
Hs.529862 Hs.712555 |
53 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytosol protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Wnt signaling pathway Hedgehog signaling pathway |
220747_at |
HSPC072 |
hypothetical LOC29075 |
20 |
-18716614, -18716614 |
NM_014162 |
29075 |
20p11.23 |
Hs.584899 |
4 |
|
|
213805_at |
ABHD5 |
abhydrolase domain containing 5 |
3 |
43707378 |
AI692428 |
51099 |
3p21 |
Hs.19385 |
14 |
1-acylglycerol-3-phosphate O-acyltransferase activity triacylglycerol lipase activity protein binding cytoplasm cytosol lipid metabolic process fatty acid metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process negative regulation of sequestering of triglyceride positive regulation of triglyceride catabolic process monolayer-surrounded lipid storage body transferase activity hydrolase activity cell differentiation lysophosphatidic acid acyltransferase activity |
|
226281_at |
0.717 |
2.831 |
2.135 |
4.938e-02 |
0.590 |
-3.893 |
DNER |
delta/notch-like EGF repeat containing |
2 |
-229930588 |
BF059512 |
92737 |
2q36.3 |
Hs.234074 |
9 |
neuron migration transmembrane receptor activity Notch binding calcium ion binding early endosome plasma membrane endocytosis Notch receptor processing synaptogenesis central nervous system development glial cell differentiation integral to membrane clathrin binding dendrite cell soma skeletal muscle fiber development |
|
201713_s_at |
RANBP2 |
RAN binding protein 2 |
2 |
108702368 |
D42063 |
5903 |
2q12.3 |
Hs.199561 Hs.715056 |
61 |
peptidyl-prolyl cis-trans isomerase activity protein binding intracellular nucleus nuclear pore cytosol protein folding protein import into nucleus zinc ion binding Ran GTPase binding protein transport isomerase activity modification-dependent protein catabolic process metal ion binding intracellular transport mRNA transport intracellular protein transmembrane transport |
|
1555515_a_at |
FAM189B |
family with sequence similarity 189, member B |
1 |
-153483619 |
BC008854 |
10712 |
1q21 |
Hs.348308 |
6 |
molecular_function biological_process membrane integral to membrane WW domain binding |
|
222982_x_at |
SLC38A2 |
solute carrier family 38, member 2 |
12 |
-45038238 |
AF298897 |
54407 |
12q |
Hs.221847 |
20 |
plasma membrane ion transport sodium ion transport amino acid transport symporter activity integral to membrane sodium ion binding |
|
210479_s_at |
0.816 |
6.339 |
2.921 |
1.041e-02 |
0.418 |
-2.591 |
RORA |
RAR-related orphan receptor A |
15 |
-58567776, -58567776, -58567776 |
L14611 |
6095 |
15q22.2 |
Hs.560343 Hs.655155 |
33 |
transcription factor activity steroid hormone receptor activity protein binding nucleus regulation of transcription, DNA-dependent nitric oxide biosynthetic process signal transduction zinc ion binding cerebellar Purkinje cell differentiation regulation of macrophage activation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cGMP metabolic process metal ion binding |
|
215711_s_at |
0.444 |
5.266 |
2.180 |
4.540e-02 |
0.581 |
-3.825 |
WEE1 |
WEE1 homolog (S. pombe) |
11 |
9551803, 9552809 |
AJ277546 |
7465 |
11p15.3-p15.1 |
Hs.249441 |
61 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm protein amino acid phosphorylation cell cycle mitosis transferase activity cell division |
Cell cycle |
223770_x_at |
MRI1 |
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae) |
19 |
13736336 |
BC001703 |
84245 |
19p13.2 |
Hs.439370 |
11 |
cellular amino acid biosynthetic process methionine biosynthetic process isomerase activity identical protein binding cellular biosynthetic process S-methyl-5-thioribose-1-phosphate isomerase activity |
|
217792_at |
SNX5 |
sorting nexin 5 |
20 |
-17870243, -17870243 |
NM_014426 |
27131 |
20p11 |
Hs.316890 |
14 |
protein binding cell communication protein transport phosphoinositide binding |
|
1554400_at |
-0.170 |
4.057 |
-2.176 |
4.571e-02 |
0.581 |
-3.830 |
TCTE3 |
t-complex-associated-testis-expressed 3 |
6 |
-169882139 |
AF519569 |
6991 |
6q27 |
Hs.584808 |
3 |
membrane |
|
212343_at |
YIPF6 |
Yip1 domain family, member 6 |
X |
67635610 |
AL117461 |
286451 |
Xq12 |
Hs.700646 Hs.82719 |
10 |
endoplasmic reticulum membrane integral to membrane |
|
219091_s_at |
MMRN2 |
multimerin 2 |
10 |
-88685279 |
NM_024756 |
79812 |
10q23.2 |
Hs.524479 Hs.719260 |
7 |
extracellular region basement membrane extracellular space |
|
204068_at |
STK3 |
serine/threonine kinase 3 (STE20 homolog, yeast) |
8 |
-99536036 |
NM_006281 |
6788 |
8q22.2 |
Hs.492333 |
22 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein amino acid phosphorylation signal transduction protein kinase cascade transferase activity positive regulation of apoptosis protein dimerization activity |
MAPK signaling pathway |
208223_s_at |
ACVR1B |
activin A receptor, type IB |
12 |
50631752, 50631752, 50631752 |
NM_020327 |
91 |
12q13 |
Hs.438918 |
39 |
G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding in utero embryonic development hair follicle development protein serine/threonine kinase activity receptor activity ATP binding integral to plasma membrane induction of apoptosis signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway embryonic development cell surface membrane activin receptor activity, type I transferase activity peptidyl-threonine phosphorylation growth factor binding manganese ion binding negative regulation of cell growth ubiquitin protein ligase binding positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of erythrocyte differentiation SMAD binding protein amino acid autophosphorylation activin binding |
MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia |
214363_s_at |
MATR3 |
matrin 3 |
5 |
138637690, 138657253 |
AA129420 |
9782 |
5q31.2 |
Hs.268939 |
24 |
nucleotide binding RNA binding structural molecule activity protein binding intracellular nucleus nuclear inner membrane zinc ion binding nuclear matrix metal ion binding |
|
240200_at |
SULT1C2 |
sulfotransferase family, cytosolic, 1C, member 2 |
2 |
108271526 |
AI307799 |
6819 |
2q11.1-q11.2 |
Hs.436123 |
19 |
cytoplasm cytoskeleton sulfotransferase activity amine metabolic process transferase activity |
|
220924_s_at |
0.655 |
9.558 |
2.138 |
4.916e-02 |
0.590 |
-3.890 |
SLC38A2 |
solute carrier family 38, member 2 |
12 |
-45038238 |
NM_018976 |
54407 |
12q |
Hs.221847 |
20 |
plasma membrane ion transport sodium ion transport amino acid transport symporter activity integral to membrane sodium ion binding |
|
1554451_s_at |
DNAJC14 |
DnaJ (Hsp40) homolog, subfamily C, member 14 |
12 |
-54501010 |
AF141342 |
85406 |
12q13.2 |
Hs.709320 |
10 |
endoplasmic reticulum protein folding protein transport membrane integral to membrane heat shock protein binding unfolded protein binding |
|
236009_at |
PERP |
PERP, TP53 apoptosis effector |
6 |
-138451335 |
AI767250 |
64065 |
6q24 |
Hs.201446 |
14 |
protein binding mitochondrion Golgi apparatus plasma membrane integral to plasma membrane apoptosis induction of apoptosis cell adhesion cell junction desmosome |
p53 signaling pathway |
241403_at |
CLK4 |
CDC-like kinase 4 |
5 |
-177962270 |
AA468591 |
57396 |
5q35 |
Hs.406557 |
7 |
nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity ATP binding nucleus transferase activity peptidyl-tyrosine phosphorylation protein amino acid autophosphorylation |
|
242180_at |
TSPAN16 |
tetraspanin 16 |
19 |
11267823 |
AI688554 |
26526 |
19p13.2 |
Hs.579784 |
2 |
membrane integral to membrane |
|
225115_at |
HIPK2 |
homeodomain interacting protein kinase 2 |
7 |
-138896855 |
BF529628 |
28996 |
7q32-q34 |
Hs.397465 Hs.632033 |
66 |
nucleotide binding transcription corepressor activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm centrosome protein amino acid phosphorylation apoptosis DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator induction of apoptosis by intracellular signals PML body transferase activity virus-host interaction positive regulation of transforming growth factor beta receptor signaling pathway nuclear membrane regulation of transcription positive regulation of transcription, DNA-dependent positive regulation of JNK cascade virion binding |
|
205097_at |
SLC26A2 |
solute carrier family 26 (sulfate transporter), member 2 |
5 |
149320492 |
AI025519 |
1836 |
5q31-q34 |
Hs.302738 |
24 |
transporter activity membrane fraction integral to plasma membrane transport secondary active sulfate transmembrane transporter activity sulfate transport membrane |
|
203162_s_at |
KATNB1 |
katanin p80 (WD repeat containing) subunit B 1 |
16 |
56327160 |
NM_005886 |
10300 |
16q21 |
Hs.275675 |
14 |
spindle pole cytoplasm cytoskeleton microtubule protein targeting negative regulation of microtubule depolymerization cell cycle mitosis microtubule binding katanin complex microtubule-severing ATPase activity axon positive regulation of microtubule depolymerization dynein binding protein heterodimerization activity cell division |
|
1554086_at |
TUBGCP3 |
tubulin, gamma complex associated protein 3 |
13 |
-112187328 |
BC007763 |
10426 |
13q34 |
Hs.224152 |
8 |
structural constituent of cytoskeleton protein binding cytoplasm centriole polar microtubule microtubule microtubule nucleation gamma-tubulin binding |
|
1559520_at |
GYPA |
glycophorin A (MNS blood group) |
4 |
-145249905 |
AL833104 |
2993 |
4q28.2-q31.1 |
Hs.434973 |
60 |
membrane fraction plasma membrane integral to membrane identical protein binding |
Hematopoietic cell lineage |
209232_s_at |
DCTN5 |
dynactin 5 (p25) |
16 |
23560307 |
BC004191 |
84516 |
16p12.2 |
Hs.435941 |
7 |
cytoplasm cytoskeleton transferase activity |
|
220135_s_at |
-0.321 |
4.519 |
-2.517 |
2.349e-02 |
0.507 |
-3.277 |
SLC7A9 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 |
19 |
-38013258 |
NM_014270 |
11136 |
19q13.1 |
Hs.719221 |
34 |
plasma membrane integral to plasma membrane protein complex assembly cellular amino acid metabolic process transport neutral amino acid transmembrane transporter activity L-cystine transmembrane transporter activity neutral amino acid transport peptide antigen binding |
|
206731_at |
CNKSR2 |
connector enhancer of kinase suppressor of Ras 2 |
X |
21302900 |
NM_014927 |
22866 |
Xp22.12 |
Hs.555917 |
10 |
protein binding cytoplasm centrosome plasma membrane regulation of signal transduction |
|
214936_at |
LRCH1 |
leucine-rich repeats and calponin homology (CH) domain containing 1 |
13 |
46025303 |
AW298219 |
23143 |
13q14.13-q14.2 |
Hs.507971 Hs.595310 Hs.656722 Hs.681314 |
9 |
protein binding |
|
228408_s_at |
SDAD1 |
SDA1 domain containing 1 |
4 |
-77090091 |
AI738666 |
55153 |
4q21.1 |
Hs.632604 |
9 |
protein binding nucleus nucleolus protein transport ribosome biogenesis |
|
216843_x_at |
PMS2L1 |
postmeiotic segregation increased 2-like 1 pseudogene |
7 |
-99756198 |
U38964 |
5379 |
7q22.1 |
Hs.634244 Hs.661055 Hs.709266 |
7 |
molecular_function ATP binding cellular_component mismatch repair biological_process kinase activity transferase activity mismatched DNA binding |
|
1553227_s_at |
0.355 |
5.098 |
2.503 |
2.416e-02 |
0.511 |
-3.301 |
BRWD1 |
bromodomain and WD repeat domain containing 1 |
21 |
-39590234, -39484017, -39479273 |
NM_018963 |
54014 |
21q22.2 |
Hs.654740 |
8 |
protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter biological_process transcription regulator activity regulation of transcription |
|
239438_at |
RAPGEF6 |
Rap guanine nucleotide exchange factor (GEF) 6 |
5 |
-130789502 |
AW169970 |
51735 |
5q31.1 |
Hs.483329 |
13 |
guanyl-nucleotide exchange factor activity intracellular cytoplasm plasma membrane signal transduction Ras protein signal transduction Ras GTPase binding GTP-dependent protein binding regulation of GTPase activity regulation of small GTPase mediated signal transduction |
|
221558_s_at |
LEF1 |
lymphoid enhancer-binding factor 1 |
4 |
-109188149 |
AF288571 |
51176 |
4q23-q25 |
Hs.719332 |
85 |
negative regulation of transcription from RNA polymerase II promoter somitogenesis epithelial to mesenchymal transition placenta development chromatin binding RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex nucleolus cytoplasm DNA bending activity transcription activator activity dentate gyrus development regulation of Wnt receptor signaling pathway embryonic limb morphogenesis mammary gland development odontogenesis of dentine-containing tooth sequence-specific DNA binding regulation of transcription negative regulation of striated muscle development positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm formation cell development palate development |
Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
1552682_a_at |
CASC5 |
cancer susceptibility candidate 5 |
15 |
38673738 |
NM_144508 |
57082 |
15q14 |
Hs.181855 |
16 |
acrosomal vesicle acrosome assembly protein binding nucleus |
|
222869_s_at |
ELAC1 |
elaC homolog 1 (E. coli) |
18 |
46748384 |
AI669235 |
55520 |
18q21 |
Hs.657360 |
9 |
endonuclease activity nucleus tRNA processing zinc ion binding hydrolase activity metal ion binding |
|
1553663_a_at |
-0.282 |
7.600 |
-2.973 |
9.364e-03 |
0.401 |
-2.500 |
NPB |
neuropeptide B |
17 |
77453363, 2419653 |
NM_148896 |
256933 |
17q25.3 |
Hs.585089 Hs.708916 |
5 |
protein binding extracellular region neuropeptide signaling pathway |
|
1562844_at |
LOC339822 |
hypothetical protein LOC339822 |
2 |
|
BC043553 |
339822 |
2p25.3 |
Hs.651879 |
1 |
|
|
224392_s_at |
-0.520 |
4.446 |
-3.629 |
2.424e-03 |
0.284 |
-1.351 |
OPN3 |
opsin 3 |
1 |
-239823074 |
AF303588 |
23596 |
1q43 |
Hs.409081 Hs.719236 |
10 |
integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway visual perception phototransduction G-protein coupled photoreceptor activity membrane protein-chromophore linkage regulation of circadian rhythm response to stimulus |
|
224897_at |
WDR26 |
WD repeat domain 26 |
1 |
-222639467 |
BF510490 |
80232 |
1q42.11-q42.12 |
Hs.497873 |
8 |
cytoplasm |
|
219568_x_at |
SOX18 |
SRY (sex determining region Y)-box 18 |
20 |
-62149522 |
NM_018419 |
54345 |
20q13.33 |
Hs.8619 |
20 |
angiogenesis vasculogenesis transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter |
|
237755_s_at |
-0.198 |
3.810 |
-2.269 |
3.821e-02 |
0.565 |
-3.682 |
WDR16 |
WD repeat domain 16 |
17 |
9420668 |
AW673231 |
146845 |
17p13.1 |
Hs.232270 |
5 |
protein binding cytoplasm |
|
230089_s_at |
C19orf6 |
chromosome 19 open reading frame 6 |
19 |
-960649 |
AA829838 |
91304 |
19p13.3 |
Hs.515003 |
6 |
cytoplasm membrane integral to membrane |
|
228318_s_at |
CRIPAK |
cysteine-rich PAK1 inhibitor |
4 |
1375339 |
AI356283 |
285464 |
4p16.3 |
Hs.26410 |
3 |
protein binding nucleus cytoplasm endoplasmic reticulum plasma membrane negative regulation of protein kinase activity ER-nuclear signaling pathway response to estrogen stimulus regulation of cytoskeleton organization |
|
210719_s_at |
0.426 |
5.457 |
2.968 |
9.468e-03 |
0.402 |
-2.510 |
HMG20B |
high-mobility group 20B |
19 |
3523942 |
BC002552 |
10362 |
19p13.3 |
Hs.406534 |
18 |
transcription factor activity nucleus regulation of transcription, DNA-dependent cell cycle chromatin modification |
|
234950_s_at |
RFWD2 |
ring finger and WD repeat domain 2 |
1 |
-174180589 |
AK001278 |
64326 |
1q25.1-q25.2 |
Hs.523744 |
12 |
protein binding nucleus cytoplasm zinc ion binding nuclear speck ligase activity modification-dependent protein catabolic process metal ion binding |
p53 signaling pathway Ubiquitin mediated proteolysis |
1564504_at |
-0.302 |
4.101 |
-2.327 |
3.417e-02 |
0.553 |
-3.590 |
ACCN5 |
amiloride-sensitive cation channel 5, intestinal |
4 |
-156970330 |
AJ252011 |
51802 |
4q31.3-q32 |
Hs.381349 |
1 |
ion channel activity sodium channel activity plasma membrane ion transport sodium ion transport integral to membrane sodium ion binding |
|
218702_at |
SARS2 |
seryl-tRNA synthetase 2, mitochondrial |
19 |
-44097743 |
NM_017827 |
54938 |
19q13.2 |
Hs.709416 |
11 |
nucleotide binding serine-tRNA ligase activity protein binding ATP binding cytoplasm mitochondrion mitochondrial matrix seryl-tRNA aminoacylation ligase activity |
Aminoacyl-tRNA biosynthesis |
230802_at |
0.602 |
3.816 |
2.617 |
1.925e-02 |
0.489 |
-3.110 |
ARHGAP24 |
Rho GTPase activating protein 24 |
4 |
86615307, 86918874, 87070449 |
AI761947 |
83478 |
4q21.23-q21.3 |
Hs.444229 |
14 |
angiogenesis GTPase activator activity protein binding intracellular cytoplasm cytoskeleton adherens junction focal adhesion signal transduction multicellular organismal development cell junction cell differentiation cell projection |
|
224984_at |
NFAT5 |
nuclear factor of activated T-cells 5, tonicity-responsive |
16 |
68156497 |
W61007 |
10725 |
16q22.1 |
Hs.371987 |
35 |
cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent signal transduction excretion positive regulation of transcription from RNA polymerase II promoter |
Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway |
1552904_at |
-0.235 |
2.094 |
-2.248 |
3.985e-02 |
0.568 |
-3.717 |
NETO1 |
neuropilin (NRP) and tolloid (TLL)-like 1 |
18 |
-68652254, -68565766, -68565766 |
NM_138999 |
81832 |
18q22-q23 |
Hs.465407 |
4 |
receptor activity extracellular region plasma membrane integral to membrane |
|
205084_at |
BCAP29 |
B-cell receptor-associated protein 29 |
7 |
107007657, 107008439 |
NM_018844 |
55973 |
7q22-q31 |
Hs.303787 |
12 |
endoplasmic reticulum intracellular protein transport apoptosis membrane integral to membrane vesicle-mediated transport |
|
224860_at |
-0.554 |
6.256 |
-2.131 |
4.980e-02 |
0.591 |
-3.900 |
C9orf123 |
chromosome 9 open reading frame 123 |
9 |
-7786490 |
AL137489 |
90871 |
9p24.1 |
Hs.7517 |
4 |
membrane integral to membrane |
|
221012_s_at |
TRIM8 |
tripartite motif-containing 8 |
10 |
104394241 |
NM_030912 |
81603 |
10q24.3 |
Hs.336810 |
7 |
protein binding biological_process zinc ion binding PML body protein homodimerization activity metal ion binding |
|
209719_x_at |
SERPINB3 |
serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
18 |
-59473410 |
U19556 |
6317 |
18q21.3 |
Hs.227948 |
37 |
serine-type endopeptidase inhibitor activity protein binding cytoplasm peptidase inhibitor activity |
|
201412_at |
LRP10 |
low density lipoprotein receptor-related protein 10 |
14 |
22410799 |
NM_014045 |
26020 |
14q11.2 |
Hs.525232 |
9 |
receptor activity low-density lipoprotein receptor activity coated pit lipid metabolic process lipid transport endocytosis membrane integral to membrane |
|
205483_s_at |
ISG15 |
ISG15 ubiquitin-like modifier |
1 |
938709 |
NM_005101 |
9636 |
1p36.33 |
Hs.458485 |
61 |
protein binding extracellular region extracellular space cytoplasm cell-cell signaling response to virus modification-dependent protein catabolic process protein tag ISG15-protein conjugation interspecies interaction between organisms |
RIG-I-like receptor signaling pathway |
232512_at |
SCN3A |
sodium channel, voltage-gated, type III, alpha subunit |
2 |
-165652275 |
AB037777 |
6328 |
2q24 |
Hs.435274 |
16 |
voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport membrane integral to membrane sodium ion binding |
|
242912_at |
-0.377 |
4.911 |
-2.379 |
3.088e-02 |
0.542 |
-3.506 |
P704P |
prostate-specific P704P |
14 |
-19053953 |
AI041215 |
641455 |
14q11.2 |
Hs.654289 |
3 |
|
|
205202_at |
PCMT1 |
protein-L-isoaspartate (D-aspartate) O-methyltransferase |
6 |
150112523 |
NM_005389 |
5110 |
6q24-q25 |
Hs.279257 |
25 |
protein-L-isoaspartate (D-aspartate) O-methyltransferase activity cellular_component cytoplasm endoplasmic reticulum protein modification process protein amino acid methylation methyltransferase activity transferase activity protein repair identical protein binding |
|
201923_at |
PRDX4 |
peroxiredoxin 4 |
X |
23595565 |
NM_006406 |
10549 |
Xp22.11 |
Hs.83383 |
15 |
cytoplasm mitochondrion I-kappaB phosphorylation thioredoxin peroxidase activity oxidoreductase activity cell redox homeostasis oxidation reduction |
|
228286_at |
GEN1 |
Gen homolog 1, endonuclease (Drosophila) |
2 |
17798657, 17798894 |
AK025489 |
348654 |
2p24.2 |
Hs.467793 |
4 |
magnesium ion binding DNA binding endonuclease activity nucleus DNA repair response to DNA damage stimulus hydrolase activity |
|
243296_at |
-0.929 |
5.401 |
-3.265 |
5.145e-03 |
0.347 |
-1.991 |
NAMPT |
nicotinamide phosphoribosyltransferase |
7 |
-105675967 |
AA873350 |
10135 |
7q22.3 |
Hs.489615 |
98 |
cytokine activity cytoplasm cytosol signal transduction cell-cell signaling positive regulation of cell proliferation NAD biosynthetic process transferase activity, transferring glycosyl groups pyridine nucleotide biosynthetic process nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity |
Nicotinate and nicotinamide metabolism |
207063_at |
NCRNA00185 |
non-protein coding RNA 185 |
Y |
-19493776 |
NM_018542 |
55410 |
Yq11.222 |
Hs.138453 |
1 |
|
|
217413_s_at |
TNXB |
tenascin XB |
6 |
-32116910, -32116910, -3416089, -3416089, -3223932, -3223932 |
X71923 |
7148 |
6p21.3 |
Hs.42853 Hs.485104 |
42 |
integrin binding extracellular region proteinaceous extracellular matrix fibrillar collagen intracellular cell adhesion signal transduction heparin binding actin cytoskeleton organization collagen metabolic process elastic fiber assembly |
Focal adhesion ECM-receptor interaction |
210864_x_at |
HFE |
hemochromatosis |
6 |
26195487 |
AF144240 |
3077 |
6p21.3 |
Hs.233325 |
592 |
antigen processing and presentation of peptide antigen via MHC class I iron ion binding protein binding cytoplasm early endosome plasma membrane integral to plasma membrane protein complex assembly ion transport iron ion transport cellular iron ion homeostasis receptor-mediated endocytosis immune response antigen processing and presentation cytoplasmic vesicle MHC class I protein complex apical part of cell basal part of cell perinuclear region of cytoplasm recycling endosome |
|
221478_at |
0.422 |
7.092 |
2.491 |
2.475e-02 |
0.513 |
-3.321 |
BNIP3L |
BCL2/adenovirus E1B 19kDa interacting protein 3-like |
8 |
26296439 |
AL132665 |
665 |
8p21 |
Hs.131226 |
19 |
lamin binding lamin binding nucleus nuclear envelope mitochondrion mitochondrial envelope endoplasmic reticulum induction of apoptosis negative regulation of survival gene product expression membrane integral to membrane protein homodimerization activity negative regulation of apoptosis interspecies interaction between organisms protein heterodimerization activity defense response to virus |
|
222723_at |
VWA1 |
von Willebrand factor A domain containing 1 |
1 |
1360771 |
AW292148 |
64856 |
1p36.33 |
Hs.449009 |
6 |
extracellular region basement membrane |
|
243277_x_at |
MECOM |
MDS1 and EVI1 complex locus |
3 |
-170283980, -170283980, -170283980, -170283980 |
AI458437 |
2122 |
3q24-q28 |
Hs.659873 Hs.719216 |
46 |
molecular_function DNA binding transcription factor activity protein binding intracellular nucleus multicellular organismal development biological_process zinc ion binding metal ion binding |
MAPK signaling pathway Pathways in cancer Chronic myeloid leukemia |
1566701_at |
VRK3 |
vaccinia related kinase 3 |
19 |
-55171535 |
AK074461 |
51231 |
19q13 |
Hs.443330 |
7 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation transferase activity |
|
219153_s_at |
THSD4 |
thrombospondin, type I, domain containing 4 |
15 |
69220841 |
NM_024817 |
79875 |
15q23 |
Hs.387057 |
6 |
metalloendopeptidase activity extracellular region proteinaceous extracellular matrix peptidase activity |
|
225497_at |
ATE1 |
arginyltransferase 1 |
10 |
-123492614 |
AL589591 |
11101 |
10q26.13 |
Hs.632080 |
6 |
arginyltransferase activity nucleus cytoplasm acyltransferase activity protein arginylation transferase activity modification-dependent protein catabolic process |
|
224703_at |
0.305 |
7.580 |
2.219 |
4.209e-02 |
0.575 |
-3.762 |
DCAF5 |
DDB1 and CUL4 associated factor 5 |
14 |
-68587390 |
AI814644 |
8816 |
14q23-q24.1 |
Hs.509780 |
6 |
|
|
1570015_at |
RP11-165H20.1 |
CHIA-like pseudogene |
1 |
111624668 |
BC031662 |
149620 |
1p13.2 |
|
1 |
|
|
1007_s_at |
0.442 |
7.747 |
2.269 |
3.822e-02 |
0.565 |
-3.683 |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
6 |
30959839, 30960305, 30964443, 2300465, 2300931, 2305069, 2098794, 2099260, 2103398 |
U48705 |
780 |
6p21.3 |
Hs.631988 |
60 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity protein binding ATP binding extracellular region integral to plasma membrane protein amino acid phosphorylation cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway membrane transferase activity |
|
205284_at |
URB2 |
URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
1 |
227828603 |
NM_014777 |
9816 |
1q42.13 |
Hs.533628 |
5 |
nucleus nucleolus |
|
219015_s_at |
ALG13 |
asparagine-linked glycosylation 13 homolog (S. cerevisiae) |
X |
110811068 |
NM_018466 |
79868 |
Xq23 |
Hs.443061 |
14 |
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity endoplasmic reticulum carbohydrate metabolic process transferase activity, transferring hexosyl groups carbohydrate binding lipid glycosylation |
N-Glycan biosynthesis Metabolic pathways |
225486_at |
ARID2 |
AT rich interactive domain 2 (ARID, RFX-like) |
12 |
44409886 |
AB046777 |
196528 |
12q12 |
Hs.317304 |
13 |
DNA binding protein binding intracellular nucleus zinc ion binding chromatin modification regulation of transcription metal ion binding |
|
214036_at |
EFNA5 |
ephrin-A5 |
5 |
-106740488 |
BE464799 |
1946 |
5q21 |
Hs.288741 |
27 |
protein binding extracellular space plasma membrane cell-cell signaling multicellular organismal development nervous system development cell differentiation anchored to plasma membrane ephrin receptor binding |
Axon guidance |
206342_x_at |
IDS |
iduronate 2-sulfatase |
X |
-148376566, -148368202 |
NM_006123 |
3423 |
Xq28 |
Hs.460960 |
73 |
iduronate-2-sulfatase activity calcium ion binding lysosome metabolic process hydrolase activity glycosaminoglycan metabolic process |
Glycosaminoglycan degradation Metabolic pathways Lysosome |
217182_at |
MUC5AC |
mucin 5AC, oligomeric mucus/gel-forming |
11 |
1132473 |
Z34282 |
4586 |
11p15.5 |
Hs.534332 Hs.558950 |
95 |
molecular_function protein binding extracellular region apoptosis induction of apoptosis cell adhesion digestion biological_process negative regulation of cell proliferation extracellular matrix constituent, lubricant activity negative regulation of cell migration fibril fibril organization |
|
231299_at |
0.353 |
4.575 |
3.344 |
4.370e-03 |
0.328 |
-1.852 |
AGAP3 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 |
7 |
150414758, 150414758 |
AI494590 |
116988 |
7q36.1 |
Hs.647075 |
8 |
nucleotide binding GTP binding intracellular cytoplasm small GTPase mediated signal transduction ARF GTPase activator activity zinc ion binding regulation of ARF GTPase activity metal ion binding |
|
210081_at |
AGER |
advanced glycosylation end product-specific receptor |
6 |
-32256723, -3555933, -3363712 |
AB036432 |
177 |
6p21.3 |
Hs.534342 |
212 |
transmembrane receptor activity protein binding extracellular region plasma membrane integral to plasma membrane inflammatory response cell surface receptor linked signal transduction |
|
1564490_at |
LOC100128830 |
hypothetical protein LOC100128830 |
10 |
|
AK097584 |
100128830 |
10q26.3 |
Hs.638406 |
1 |
|
|
209292_at |
ID4 |
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
6 |
19945595 |
AL022726 |
3400 |
6p22-p21 |
Hs.519601 |
23 |
G1/S transition of mitotic cell cycle transcription corepressor activity protein binding nucleus nucleus regulation of transcription from RNA polymerase II promoter neuroblast proliferation brain development positive regulation of cell proliferation negative regulation of transcription hippocampus development cerebral cortex neuron differentiation negative regulation of neuron differentiation negative regulation of astrocyte differentiation |
TGF-beta signaling pathway |
232165_at |
-0.303 |
3.614 |
-2.316 |
3.489e-02 |
0.555 |
-3.607 |
EPPK1 |
epiplakin 1 |
8 |
-145011899 |
AL137725 |
83481 |
8q24.3 |
Hs.200412 |
11 |
structural molecule activity protein binding cytoplasm cytoskeleton biological_process |
|
221706_s_at |
USE1 |
unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
19 |
17187154 |
BC006005 |
55850 |
19p13.11 |
Hs.16187 |
12 |
protein binding lysosome endoplasmic reticulum ER to Golgi vesicle-mediated transport lysosomal transport protein transport membrane integral to membrane vesicle-mediated transport protein catabolic process |
SNARE interactions in vesicular transport |
204794_at |
DUSP2 |
dual specificity phosphatase 2 |
2 |
-96172634 |
NM_004418 |
1844 |
2q11 |
Hs.1183 |
16 |
inactivation of MAPK activity protein tyrosine phosphatase activity nucleus protein amino acid dephosphorylation protein tyrosine/threonine phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity mitogen-activated protein kinase binding |
MAPK signaling pathway |
202594_at |
0.352 |
6.966 |
2.402 |
2.949e-02 |
0.536 |
-3.467 |
LEPROTL1 |
leptin receptor overlapping transcript-like 1 |
8 |
30072463, 30072463 |
NM_015344 |
23484 |
8p21.2-p21.1 |
Hs.146585 |
8 |
membrane integral to membrane |
|
200093_s_at |
0.304 |
10.848 |
2.606 |
1.968e-02 |
0.491 |
-3.129 |
HINT1 |
histidine triad nucleotide binding protein 1 |
5 |
-130522773, -130522773 |
N32864 |
3094 |
5q31.2 |
Hs.483305 |
26 |
protein kinase C binding nucleus cytoplasm cytoskeleton signal transduction hydrolase activity |
|
206311_s_at |
PLA2G1B |
phospholipase A2, group IB (pancreas) |
12 |
-119244296 |
NM_000928 |
5319 |
12q23-q24.1 |
Hs.992 |
44 |
activation of MAPK activity neutrophil mediated immunity receptor binding calcium ion binding extracellular region extracellular space fatty acid biosynthetic process phospholipid metabolic process actin filament organization signal transduction protein kinase cascade positive regulation of calcium ion transport into cytosol positive regulation of specific transcription from RNA polymerase II promoter glucose transport hydrolase activity leukotriene biosynthetic process neutrophil chemotaxis bile acid binding activation of phospholipase A2 activity interleukin-8 production cellular response to insulin stimulus cell surface binding multicellular organismal lipid catabolic process positive regulation of DNA replication phosphatidylcholine metabolic process calcium-dependent phospholipase A2 activity positive regulation of fibroblast proliferation arachidonic acid secretion positive regulation of protein secretion positive regulation of immune response positive regulation of NF-kappaB transcription factor activity |
Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Long-term depression GnRH signaling pathway |
235197_s_at |
0.342 |
3.827 |
2.322 |
3.449e-02 |
0.553 |
-3.598 |
OSTM1 |
osteopetrosis associated transmembrane protein 1 |
6 |
-108469305 |
AV713913 |
28962 |
6q21 |
Hs.226780 Hs.706947 Hs.719130 |
16 |
protein binding cytosol membrane integral to membrane osteoclast differentiation |
|
220683_at |
RDH8 |
retinol dehydrogenase 8 (all-trans) |
19 |
9984924 |
NM_015725 |
50700 |
19p13.2-p13.3 |
Hs.675522 |
9 |
estradiol 17-beta-dehydrogenase activity retinol dehydrogenase activity binding cytoplasm integral to plasma membrane estrogen biosynthetic process visual perception membrane oxidoreductase activity response to stimulus oxidation reduction |
Retinol metabolism Metabolic pathways |
205757_at |
ENTPD5 |
ectonucleoside triphosphate diphosphohydrolase 5 |
14 |
-73502935 |
NM_001249 |
957 |
14q24 |
Hs.131555 |
14 |
magnesium ion binding calcium ion binding endoplasmic reticulum endoplasmic reticulum lumen hydrolase activity nucleoside-diphosphatase activity |
Purine metabolism Pyrimidine metabolism |
233134_at |
RPH3AL |
rabphilin 3A-like (without C2 domains) |
17 |
-62293 |
T74766 |
9501 |
17p13.3 |
Hs.651925 |
15 |
cytoplasm intracellular protein transport exocytosis cytoskeletal protein binding zinc ion binding membrane Rab GTPase binding secretory granule membrane cytoplasmic vesicle metal ion binding |
|
241402_at |
TSEN54 |
tRNA splicing endonuclease 54 homolog (S. cerevisiae) |
17 |
71024203 |
AA504269 |
283989 |
17q25.1 |
Hs.655875 |
6 |
nucleus nucleolus tRNA splicing, via endonucleolytic cleavage and ligation mRNA processing |
|
204537_s_at |
GABRE |
gamma-aminobutyric acid (GABA) A receptor, epsilon |
X |
-150872251 |
NM_004961 |
2564 |
Xq28 |
Hs.22785 |
17 |
GABA-A receptor activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity plasma membrane integral to plasma membrane ion transport gamma-aminobutyric acid signaling pathway cell junction neurotransmitter receptor activity chloride ion binding chloride channel complex synapse postsynaptic membrane |
Neuroactive ligand-receptor interaction |
225053_at |
CNOT7 |
CCR4-NOT transcription complex, subunit 7 |
8 |
-17133392, -17131110 |
W94952 |
29883 |
8p22-p21.3 |
Hs.645009 Hs.719129 |
19 |
nucleic acid binding transcription factor activity signal transducer activity protein binding nucleus carbohydrate metabolic process signal transduction transcription activator activity CCR4-NOT complex regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
RNA degradation |
1554397_s_at |
UEVLD |
UEV and lactate/malate dehyrogenase domains |
11 |
-18509819 |
BC011011 |
55293 |
11p15.1 |
Hs.407991 |
5 |
binding glycolysis metabolic process protein transport oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor small conjugating protein ligase activity modification-dependent protein catabolic process post-translational protein modification cellular carbohydrate metabolic process regulation of protein metabolic process |
|
206158_s_at |
CNBP |
CCHC-type zinc finger, nucleic acid binding protein |
3 |
-130369347 |
NM_003418 |
7555 |
3q21 |
Hs.518249 |
24 |
transcription factor activity protein binding cytoplasm endoplasmic reticulum regulation of transcription, DNA-dependent cholesterol biosynthetic process zinc ion binding metal ion binding |
|
232620_at |
WDR93 |
WD repeat domain 93 |
15 |
88035031 |
AL390084 |
56964 |
15q26.1 |
Hs.177557 |
2 |
|
|
220096_at |
RNASET2 |
ribonuclease T2 |
6 |
-167262993 |
NM_017795 |
8635 |
6q27 |
Hs.529989 |
11 |
RNA binding endonuclease activity ribonuclease activity extracellular region RNA catabolic process hydrolase activity ribonuclease T2 activity |
|
227993_at |
METAP2 |
methionyl aminopeptidase 2 |
12 |
94391952 |
AW003997 |
10988 |
12q22 |
Hs.444986 |
35 |
aminopeptidase activity cytoplasm proteolysis peptidase activity metalloexopeptidase activity cellular process protein processing peptidyl-methionine modification N-terminal protein amino acid modification metal ion binding cobalt ion binding |
|
213058_at |
TTC28 |
tetratricopeptide repeat domain 28 |
22 |
-26704003 |
AL033538 |
23331 |
22q12.1 |
Hs.387856 Hs.719265 |
6 |
binding |
|
200611_s_at |
WDR1 |
WD repeat domain 1 |
4 |
-9685060 |
AB010427 |
9948 |
4p16.1 |
Hs.128548 Hs.713658 |
15 |
actin binding protein binding cytoplasm cytoskeleton sensory perception of sound |
|
220849_at |
LOC79999 |
hypothetical LOC79999 |
17 |
|
NM_024934 |
79999 |
17p11.2 |
Hs.677375 |
3 |
|
|
204582_s_at |
KLK3 |
kallikrein-related peptidase 3 |
19 |
56049982, 56049982 |
NM_001648 |
354 |
19q13.41 |
Hs.171995 |
191 |
serine-type endopeptidase activity extracellular region proteolysis peptidase activity negative regulation of angiogenesis |
Pathways in cancer Prostate cancer |
215174_at |
-0.238 |
3.911 |
-2.547 |
2.217e-02 |
0.499 |
-3.228 |
FMO6P |
flavin containing monooxygenase 6 pseudogene |
1 |
169373502 |
AL021026 |
388714 |
1q24.3 |
Hs.448988 |
4 |
monooxygenase activity flavin-containing monooxygenase activity endoplasmic reticulum microsome membrane integral to membrane intrinsic to endoplasmic reticulum membrane FAD binding NADP or NADPH binding oxidation reduction |
|
226888_at |
0.317 |
5.041 |
2.902 |
1.083e-02 |
0.421 |
-2.624 |
CSNK1G1 |
casein kinase 1, gamma 1 |
15 |
-62244768 |
BG104860 |
53944 |
15q22.1-q22.31 |
Hs.646508 |
10 |
nucleotide binding protein serine/threonine kinase activity ATP binding cytoplasm protein amino acid phosphorylation Wnt receptor signaling pathway transferase activity |
Hedgehog signaling pathway |
205549_at |
PCP4 |
Purkinje cell protein 4 |
21 |
40161216 |
NM_006198 |
5121 |
21q22.2 |
Hs.80296 |
9 |
nucleus cytosol central nervous system development |
|
202336_s_at |
0.573 |
10.263 |
3.093 |
7.317e-03 |
0.376 |
-2.291 |
PAM |
peptidylglycine alpha-amidating monooxygenase |
5 |
102229425 |
NM_000919 |
5066 |
5q14-q21 |
Hs.369430 |
34 |
monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding protein binding extracellular region protein modification process peptide metabolic process zinc ion binding cellular process membrane integral to membrane lyase activity secretory granule L-ascorbic acid binding metal ion binding oxidation reduction |
|
226453_at |
RNASEH2C |
ribonuclease H2, subunit C |
11 |
-65241719 |
BF982002 |
84153 |
11q13.1 |
Hs.718438 |
9 |
nucleus |
DNA replication |
210118_s_at |
-0.272 |
4.076 |
-2.246 |
4.000e-02 |
0.568 |
-3.720 |
IL1A |
interleukin 1, alpha |
2 |
-113247962 |
M15329 |
3552 |
2q14 |
Hs.1722 |
540 |
fever cytokine activity interleukin-1 receptor binding protein binding extracellular region extracellular space apoptosis anti-apoptosis inflammatory response immune response negative regulation of cell proliferation positive regulation vascular endothelial growth factor production cytokine-mediated signaling pathway positive regulation of interleukin-2 biosynthetic process positive regulation of angiogenesis positive regulation of mitosis positive regulation of cytokine secretion |
MAPK signaling pathway Cytokine-cytokine receptor interaction Apoptosis Hematopoietic cell lineage Type I diabetes mellitus Prion diseases Graft-versus-host disease |
212928_at |
TSPYL4 |
TSPY-like 4 |
6 |
-116677823 |
AL050331 |
23270 |
6q22.1 |
Hs.284141 |
7 |
nucleus nucleosome assembly |
|
203068_at |
KLHL21 |
kelch-like 21 (Drosophila) |
1 |
-6573370 |
NM_014851 |
9903 |
1p36.31 |
Hs.7764 |
5 |
protein binding modification-dependent protein catabolic process |
|
236328_at |
0.286 |
4.744 |
2.375 |
3.114e-02 |
0.543 |
-3.513 |
ZNF285A |
zinc finger protein 285A |
19 |
-49581647 |
AW513227 |
26974 |
|
Hs.709428 |
4 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
241009_at |
FOXN4 |
forkhead box N4 |
12 |
-108200165 |
AI243313 |
121643 |
12q24.11 |
Hs.528316 |
6 |
transcription factor activity nucleus regulation of transcription, DNA-dependent sequence-specific DNA binding |
|
1554516_at |
-0.301 |
6.898 |
-2.457 |
2.650e-02 |
0.522 |
-3.378 |
LOC203274 |
hypothetical protein LOC203274 |
9 |
|
BC011779 |
203274 |
9q21.11 |
Hs.599821 |
1 |
|
|
206973_at |
-0.315 |
4.454 |
-2.571 |
2.112e-02 |
0.497 |
-3.188 |
PPFIA2 |
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 |
12 |
-80177486 |
NM_003625 |
8499 |
12q21.31 |
Hs.506216 |
7 |
protein binding cytoplasm cell-matrix adhesion cell surface |
|
227837_at |
LOC729570 |
hypothetical LOC729570 |
2 |
|
BF057711 |
729570 |
2q33.3 |
|
|
|
|
224636_at |
ZFP91 |
zinc finger protein 91 homolog (mouse) |
11 |
58103162 |
AL045405 |
80829 |
11q12 |
Hs.524920 |
10 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
227161_at |
NOM1 |
nucleolar protein with MIF4G domain 1 |
7 |
156435177 |
AI419857 |
64434 |
7q36.3 |
Hs.15825 |
6 |
protein binding nucleus nucleolus biological_process RNA metabolic process |
|
240088_at |
PDE5A |
phosphodiesterase 5A, cGMP-specific |
4 |
-120634997, -120634997, -120634997 |
BG494416 |
8654 |
4q25-q27 |
Hs.587281 Hs.647971 |
43 |
nucleotide binding magnesium ion binding cellular_component signal transduction zinc ion binding cyclic nucleotide metabolic process hydrolase activity cGMP binding 3',5'-cyclic-GMP phosphodiesterase activity |
Purine metabolism |
203017_s_at |
SSX2IP |
synovial sarcoma, X breakpoint 2 interacting protein |
1 |
-84882184 |
R52678 |
117178 |
1p22.3 |
Hs.22587 |
14 |
protein binding nucleus adherens junction cell adhesion cell junction protein complex |
Adherens junction |
1563321_s_at |
-0.356 |
4.279 |
-2.731 |
1.533e-02 |
0.457 |
-2.918 |
MLLT10 |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
10 |
21863107, 21863579 |
AF272384 |
8028 |
10p12 |
Hs.30385 |
19 |
transcription factor activity protein binding nucleus cytoplasm zinc ion binding metal ion binding |
|
217595_at |
GSPT1 |
G1 to S phase transition 1 |
16 |
-11869485, -11869485 |
AV701723 |
2935 |
16p13.1 |
Hs.528780 |
27 |
G1/S transition of mitotic cell cycle nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translation release factor activity GTPase activity protein binding GTP binding intracellular translation protein amino acid methylation |
|
233288_at |
ATR |
ataxia telangiectasia and Rad3 related |
3 |
-143650766 |
AU143947 |
545 |
3q22-q24 |
Hs.271791 |
186 |
DNA damage checkpoint nucleotide binding XY body DNA binding protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm chromosome DNA repair protein amino acid phosphorylation response to DNA damage stimulus cell cycle multicellular organismal development negative regulation of DNA replication transferase activity manganese ion binding MutLalpha complex binding MutSalpha complex binding regulation of protein binding |
Cell cycle p53 signaling pathway |
1569383_s_at |
ZFYVE28 |
zinc finger, FYVE domain containing 28 |
4 |
-2241122 |
BC032605 |
57732 |
4p16.3 |
Hs.292056 |
3 |
protein binding cytoplasm endosome cytosol negative regulation of epidermal growth factor receptor activity zinc ion binding membrane early endosome membrane phosphatidylinositol 3-phosphate binding metal ion binding |
|
1564295_at |
FLJ25917 |
hypothetical gene supported by AK098783 |
X |
|
AK098783 |
401585 |
Xp11.3 |
Hs.633348 |
|
|
|
236382_at |
WDR8 |
WD repeat domain 8 |
1 |
-3537191 |
AW572779 |
49856 |
1p36.3 |
Hs.31714 |
8 |
protein binding cytoplasm |
|
207131_x_at |
GGT1 |
gamma-glutamyltransferase 1 |
22 |
23309717, 23329179, 23333654 |
NM_013430 |
2678 |
22q11.23 |
Hs.595809 Hs.645535 |
71 |
molecular_function gamma-glutamyltransferase activity protein binding cellular amino acid metabolic process glutathione biosynthetic process acyltransferase activity membrane integral to membrane transferase activity |
Taurine and hypotaurine metabolism Selenoamino acid metabolism Cyanoamino acid metabolism Glutathione metabolism Arachidonic acid metabolism Metabolic pathways |
227374_at |
EARS2 |
glutamyl-tRNA synthetase 2, mitochondrial (putative) |
16 |
-23440834 |
AA833716 |
124454 |
16p12.2 |
Hs.620541 |
6 |
nucleotide binding RNA binding glutamate-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix glutamyl-tRNA aminoacylation ligase activity |
Porphyrin and chlorophyll metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways |
219736_at |
TRIM36 |
tripartite motif-containing 36 |
5 |
-114541134, -114534698, -114488357 |
NM_018700 |
55521 |
5q22.3 |
Hs.519514 Hs.638953 |
5 |
acrosomal vesicle protein binding intracellular cytoplasm acrosome reaction zinc ion binding metal ion binding |
|
227961_at |
CTSB |
cathepsin B |
8 |
-11737442 |
AA130998 |
1508 |
8p22 |
Hs.520898 |
140 |
cysteine-type endopeptidase activity extracellular region intracellular soluble fraction mitochondrion lysosome proteolysis peptidase activity response to wounding external side of plasma membrane apical plasma membrane kininogen binding peptide binding melanosome regulation of apoptosis regulation of catalytic activity |
Lysosome Antigen processing and presentation |
223125_s_at |
C1orf21 |
chromosome 1 open reading frame 21 |
1 |
182622772 |
AL563236 |
81563 |
1q25 |
Hs.497159 Hs.719188 |
8 |
|
|
209990_s_at |
GABBR2 |
gamma-aminobutyric acid (GABA) B receptor, 2 |
9 |
-100090186 |
AF056085 |
9568 |
9q22.1-q22.3 |
Hs.198612 |
27 |
receptor activity G-protein coupled receptor activity GABA-B receptor activity protein binding cytoplasm plasma membrane integral to plasma membrane signal transduction negative regulation of adenylate cyclase activity gamma-aminobutyric acid signaling pathway synaptic transmission cell junction neuron projection synapse postsynaptic membrane |
Neuroactive ligand-receptor interaction |
208625_s_at |
EIF4G1 |
eukaryotic translation initiation factor 4 gamma, 1 |
3 |
185515049, 185515664, 185520956 |
AF104913 |
1981 |
3q27-qter |
Hs.433750 |
91 |
RNA binding translation initiation factor activity protein binding cytoplasm cytosol regulation of translational initiation RNA metabolic process eukaryotic translation initiation factor 4F complex interspecies interaction between organisms |
|
213465_s_at |
PPP1R7 |
protein phosphatase 1, regulatory (inhibitor) subunit 7 |
2 |
241738574 |
BF718769 |
5510 |
2q37.3 |
Hs.36587 |
10 |
protein binding nucleus cytoplasm biological_process protein phosphatase type 1 regulator activity enzyme regulator activity |
|
201410_at |
PLEKHB2 |
pleckstrin homology domain containing, family B (evectins) member 2 |
2 |
131578889 |
AI983043 |
55041 |
2q21.1 |
Hs.469944 Hs.711433 |
11 |
protein binding membrane |
|
218032_at |
SNN |
stannin |
16 |
11669801 |
AF070673 |
8303 |
16p13 |
Hs.700592 |
11 |
response to stress response to abiotic stimulus membrane integral to membrane |
|
244353_s_at |
-0.757 |
6.558 |
-4.289 |
6.274e-04 |
0.211 |
-0.208 |
SLC2A12 |
solute carrier family 2 (facilitated glucose transporter), member 12 |
6 |
-134350411 |
AI675682 |
154091 |
6q23.2 |
Hs.486508 |
11 |
transporter activity cytoplasm carbohydrate transport membrane integral to membrane substrate-specific transmembrane transporter activity perinuclear region of cytoplasm transmembrane transport |
|
218386_x_at |
USP16 |
ubiquitin specific peptidase 16 |
21 |
29318808 |
NM_006447 |
10600 |
21q22.11 |
Hs.99819 |
15 |
transcription coactivator activity cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity nucleus cytoplasm ubiquitin-dependent protein catabolic process cell cycle mitosis peptidase activity zinc ion binding chromatin modification histone deubiquitination histone binding ubiquitin binding regulation of transcription positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization cell division |
|
1553539_at |
KRT74 |
keratin 74 |
12 |
-51245869 |
NM_175053 |
121391 |
12q13.13 |
Hs.660125 |
5 |
keratin filament |
|
226902_at |
USP13 |
ubiquitin specific peptidase 13 (isopeptidase T-3) |
3 |
180853626 |
BF109140 |
8975 |
3q26.2-q26.3 |
Hs.175322 |
11 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding |
|
1555308_at |
-0.220 |
6.034 |
-2.453 |
2.666e-02 |
0.523 |
-3.383 |
CARD14 |
caspase recruitment domain family, member 14 |
17 |
75766875, 75776193 |
BC018142 |
79092 |
17q25 |
Hs.675480 Hs.696253 |
7 |
positive regulation of protein amino acid phosphorylation protein binding intracellular cytoplasm plasma membrane activation of NF-kappaB-inducing kinase activity regulation of apoptosis CARD domain binding |
|
214191_at |
ICA1 |
islet cell autoantigen 1, 69kDa |
7 |
-8119928, -8119339, -8119339 |
W67992 |
3382 |
7p22 |
Hs.487561 |
27 |
Golgi membrane molecular_function protein binding cytoplasm Golgi apparatus cytosol neurotransmitter transport membrane cell junction secretory granule membrane synaptic vesicle membrane cytoplasmic vesicle synapse |
Type I diabetes mellitus |
219293_s_at |
OLA1 |
Obg-like ATPase 1 |
2 |
-174645420 |
NM_013341 |
29789 |
2q31.1 |
Hs.157351 |
11 |
nucleotide binding protein binding ATP binding GTP binding intracellular cytoplasm ATP catabolic process hydrolase activity |
|
223993_s_at |
CNIH4 |
cornichon homolog 4 (Drosophila) |
1 |
222611217 |
AL136930 |
29097 |
1q42.11 |
Hs.195403 Hs.445890 |
11 |
protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane |
|
226274_at |
CLCN5 |
chloride channel 5 |
X |
49573964, 49718954 |
AK025562 |
1184 |
Xp11.23-p11.22 |
Hs.166486 |
45 |
nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome Golgi apparatus plasma membrane integral to plasma membrane ion transport chloride transport endocytosis excretion antiporter activity chloride ion binding apical part of cell |
|
219756_s_at |
POF1B |
premature ovarian failure, 1B |
X |
-84419050 |
NM_024921 |
79983 |
Xq21.1-q21.2 |
Hs.267038 |
10 |
actin binding |
|
202117_at |
0.357 |
7.782 |
2.303 |
3.579e-02 |
0.557 |
-3.628 |
ARHGAP1 |
Rho GTPase activating protein 1 |
11 |
-46655207 |
BG468434 |
392 |
11p12-q12 |
Hs.138860 |
39 |
ruffle SH3/SH2 adaptor activity GTPase activator activity protein binding intracellular cytoplasm plasma membrane signal transduction small GTPase mediated signal transduction Rho protein signal transduction SH3 domain binding Rac GTPase activator activity regulation of GTPase activity intracellular membrane-bounded organelle |
|
221539_at |
EIF4EBP1 |
eukaryotic translation initiation factor 4E binding protein 1 |
8 |
38007176 |
AB044548 |
1978 |
8p12 |
Hs.411641 |
107 |
protein binding cytosol eukaryotic initiation factor 4E binding insulin receptor signaling pathway negative regulation of translational initiation |
ErbB signaling pathway mTOR signaling pathway Insulin signaling pathway Acute myeloid leukemia |
209219_at |
0.358 |
7.524 |
2.283 |
3.719e-02 |
0.562 |
-3.660 |
RDBP |
RD RNA binding protein |
6 |
-32027842, -3366126, -3167604 |
L03411 |
7936 |
6p21.3 |
Hs.423935 |
34 |
nucleotide binding RNA binding protein binding nucleus nucleoplasm nucleolus mitochondrion biological_process regulation of transcription |
|
227194_at |
FAM3B |
family with sequence similarity 3, member B |
21 |
41610530 |
BF106962 |
54097 |
21q22.3 |
Hs.473877 Hs.670704 |
8 |
cytokine activity extracellular region extracellular space insulin secretion |
|
227713_at |
KATNAL1 |
katanin p60 subunit A-like 1 |
13 |
-29674766, -29674766 |
AI807482 |
84056 |
13q12.3 |
Hs.243596 |
7 |
nucleotide binding ATP binding microtubule microtubule-severing ATPase activity hydrolase activity nucleoside-triphosphatase activity |
|
205325_at |
PHYHIP |
phytanoyl-CoA 2-hydroxylase interacting protein |
8 |
-22133160 |
NM_014759 |
9796 |
8p21.3 |
Hs.334688 |
8 |
protein binding |
|
209769_s_at |
GP1BB |
glycoprotein Ib (platelet), beta polypeptide |
22 |
18091065 |
L20860 |
2812 |
22q11.21 22q11.21-q11.23 |
Hs.283743 |
45 |
transmembrane receptor activity protein binding plasma membrane integral to plasma membrane cell adhesion cell surface receptor linked signal transduction platelet activation platelet alpha granule membrane |
ECM-receptor interaction Hematopoietic cell lineage |
222722_at |
OGN |
osteoglycin |
9 |
-94186069 |
AV700059 |
4969 |
9q22 |
Hs.109439 |
24 |
molecular_function protein binding extracellular region proteinaceous extracellular matrix endoplasmic reticulum growth factor activity biological_process |
|
224569_s_at |
-0.974 |
9.181 |
-2.508 |
2.395e-02 |
0.509 |
-3.293 |
IRF2BP2 |
interferon regulatory factor 2 binding protein 2 |
1 |
-232806637 |
AW242432 |
359948 |
1q42.3 |
Hs.693837 |
5 |
nucleus regulation of transcription |
|
214769_at |
CLCN4 |
chloride channel 4 |
X |
10084984 |
AF052117 |
1183 |
Xp22.3 |
Hs.495674 |
17 |
nucleotide binding ion channel activity voltage-gated chloride channel activity ATP binding endosome ion transport chloride transport antiporter activity membrane integral to membrane chloride ion binding |
|
236126_at |
ACVR2B |
activin A receptor, type IIB |
3 |
38470793 |
AI188710 |
93 |
3p22 |
Hs.174273 |
38 |
nucleotide binding magnesium ion binding receptor activity ATP binding cytoplasm plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction anterior/posterior pattern formation cell surface activin receptor activity, type II transferase activity growth factor binding manganese ion binding positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of osteoblast differentiation |
Cytokine-cytokine receptor interaction TGF-beta signaling pathway |
217955_at |
0.292 |
7.972 |
2.209 |
4.289e-02 |
0.576 |
-3.778 |
BCL2L13 |
BCL2-like 13 (apoptosis facilitator) |
22 |
16501484 |
NM_015367 |
23786 |
22q11.1 |
Hs.631672 |
12 |
nucleus mitochondrion induction of apoptosis activation of caspase activity caspase activator activity membrane integral to membrane regulation of apoptosis |
|
224597_at |
LOC647979 |
hypothetical LOC647979 |
20 |
-34096955 |
AV729406 |
647979 |
20q11.23 |
Hs.649310 Hs.718413 |
2 |
|
|
1554586_a_at |
RHOBTB2 |
Rho-related BTB domain containing 2 |
8 |
22900874, 22909305, 22913036 |
BC034917 |
23221 |
8p21.3 |
Hs.372688 |
18 |
nucleotide binding protein binding GTP binding intracellular small GTPase mediated signal transduction |
Ubiquitin mediated proteolysis |
1554438_at |
KIAA1217 |
KIAA1217 |
10 |
24023680, 24537725 |
BC018764 |
56243 |
10p12.2-p12.1 |
Hs.445885 |
5 |
molecular_function cytoplasm multicellular organismal development embryonic skeletal system development |
|
234684_s_at |
-0.292 |
2.616 |
-3.072 |
7.640e-03 |
0.378 |
-2.327 |
KRTAP4-4 |
keratin associated protein 4-4 |
17 |
-36569431 |
AJ296168 |
84616 |
17q12-q21 |
Hs.307022 |
2 |
keratin filament |
|
225060_at |
LRP11 |
low density lipoprotein receptor-related protein 11 |
6 |
-150181586 |
BF696304 |
84918 |
6q25.1 |
Hs.408355 |
6 |
receptor activity membrane integral to membrane |
|
200064_at |
0.241 |
10.780 |
2.166 |
4.663e-02 |
0.582 |
-3.846 |
HSP90AB1 |
heat shock protein 90kDa alpha (cytosolic), class B member 1 |
6 |
44322826 |
AF275719 |
3326 |
6p12 |
Hs.509736 Hs.689683 Hs.701787 |
50 |
nucleotide binding ATP binding cytoplasm protein folding response to unfolded protein nitric-oxide synthase regulator activity TPR domain binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process melanosome positive regulation of nitric oxide biosynthetic process unfolded protein binding regulation of interferon-gamma-mediated signaling pathway regulation of type I interferon-mediated signaling pathway |
Antigen processing and presentation Pathways in cancer Prostate cancer |
211855_s_at |
SLC25A14 |
solute carrier family 25 (mitochondrial carrier, brain), member 14 |
X |
129301727 |
AF155810 |
9016 |
Xq24 |
Hs.194686 |
13 |
binding mitochondrion mitochondrial inner membrane integral to plasma membrane transport mitochondrial transport aerobic respiration membrane |
|
201784_s_at |
0.211 |
9.168 |
2.515 |
2.359e-02 |
0.508 |
-3.281 |
C11orf58 |
chromosome 11 open reading frame 58 |
11 |
16716723 |
NM_014267 |
10944 |
11p15.1 |
Hs.719128 |
8 |
molecular_function cellular_component biological_process |
|
210373_at |
TUSC4 |
tumor suppressor candidate 4 |
3 |
-50359922 |
AF040708 |
10641 |
3p21.3 |
Hs.437083 |
11 |
protein kinase activity protein binding negative regulation of kinase activity |
|
213568_at |
OSR2 |
odd-skipped related 2 (Drosophila) |
8 |
100025806 |
AI811298 |
116039 |
8q22.2 |
Hs.253247 |
6 |
nucleic acid binding intracellular nucleus zinc ion binding positive regulation of cell proliferation metal ion binding embryonic skeletal system morphogenesis |
|
1552432_at |
-0.214 |
5.215 |
-2.222 |
4.189e-02 |
0.574 |
-3.758 |
MFSD6L |
major facilitator superfamily domain containing 6-like |
17 |
-8641205 |
BC040487 |
162387 |
17p13.1 |
Hs.213603 |
2 |
membrane integral to membrane |
|
212612_at |
RCOR1 |
REST corepressor 1 |
14 |
102128985 |
D31888 |
23186 |
14q32.31 |
Hs.510521 |
28 |
DNA binding protein binding nucleus chromatin modification interspecies interaction between organisms regulation of transcription |
Huntington's disease |
232905_at |
GTF2H5 |
general transcription factor IIH, polypeptide 5 |
6 |
158509366 |
AK024874 |
404672 |
6q25.3 |
Hs.356224 |
11 |
DNA binding nucleus nucleotide-excision repair response to DNA damage stimulus regulation of transcription |
Nucleotide excision repair |
215270_at |
LFNG |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
7 |
2526004, 2526004 |
U94354 |
3955 |
7p22.2 |
Hs.159142 |
11 |
molecular_function extracellular region Golgi apparatus pattern specification process organ morphogenesis membrane integral to membrane transferase activity, transferring glycosyl groups integral to Golgi membrane O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity |
Notch signaling pathway |
223178_s_at |
NT5DC1 |
5'-nucleotidase domain containing 1 |
6 |
116528691 |
AF245044 |
221294 |
6q22.1 |
Hs.719198 |
7 |
magnesium ion binding hydrolase activity |
|
1561518_at |
LOC283914 |
hypothetical protein LOC283914 |
16 |
34455287, 34455402 |
BC038774 |
283914 |
16p11.2-p11.1 |
Hs.385772 |
1 |
|
|
1563796_s_at |
EARS2 |
glutamyl-tRNA synthetase 2, mitochondrial (putative) |
16 |
-23440834 |
AK095998 |
124454 |
16p12.2 |
Hs.620541 |
6 |
nucleotide binding RNA binding glutamate-tRNA ligase activity ATP binding cytoplasm mitochondrion mitochondrial matrix glutamyl-tRNA aminoacylation ligase activity |
Porphyrin and chlorophyll metabolism Aminoacyl-tRNA biosynthesis Metabolic pathways |
207692_s_at |
-0.243 |
5.141 |
-2.219 |
4.206e-02 |
0.575 |
-3.762 |
ACAN |
aggrecan |
15 |
87147677 |
NM_001135 |
176 |
15q26.1 |
Hs.2159 Hs.616395 Hs.711491 |
59 |
skeletal system development binding sugar binding hyaluronic acid binding extracellular region proteinaceous extracellular matrix proteolysis cell adhesion extracellular matrix structural constituent conferring compression resistance extracellular matrix organization |
|
228160_at |
0.339 |
6.157 |
2.326 |
3.421e-02 |
0.553 |
-3.591 |
LOC339290 |
hypothetical LOC339290 |
18 |
5228098 |
AI433706 |
339290 |
18p11.31 |
Hs.643553 Hs.700799 |
4 |
|
|
1556841_a_at |
ALDH1L2 |
aldehyde dehydrogenase 1 family, member L2 |
12 |
-103937693 |
AI378916 |
160428 |
12q23.3 |
Hs.42572 |
2 |
acyl carrier activity cytoplasm one-carbon metabolic process methyltransferase activity biosynthetic process 10-formyltetrahydrofolate catabolic process formyltetrahydrofolate dehydrogenase activity oxidoreductase activity hydroxymethyl-, formyl- and related transferase activity phosphopantetheine binding oxidation reduction |
|
208572_at |
HIST3H3 |
histone cluster 3, H3 |
1 |
-226679168 |
NM_003493 |
8290 |
1q42 |
Hs.248171 |
73 |
nucleosome DNA binding protein binding nucleus chromosome nucleosome assembly |
Systemic lupus erythematosus |
219038_at |
MORC4 |
MORC family CW-type zinc finger 4 |
X |
-106070619 |
NM_024657 |
79710 |
Xq22.3 |
Hs.496544 |
5 |
ATP binding zinc ion binding metal ion binding |
|
207243_s_at |
CALM2 |
calmodulin 2 (phosphorylase kinase, delta) |
2 |
-47240725 |
NM_001743 |
805 |
2p21 |
Hs.468442 |
52 |
|
Calcium signaling pathway Phosphatidylinositol signaling system Vascular smooth muscle contraction Long-term potentiation Neurotrophin signaling pathway Olfactory transduction Insulin signaling pathway GnRH signaling pathway Melanogenesis Alzheimer's disease Glioma |
225810_at |
MTMR10 |
myotubularin related protein 10 |
15 |
-29018435 |
AL572015 |
54893 |
15q13.3 |
Hs.30141 Hs.706035 |
7 |
dephosphorylation phosphatase activity |
|
225224_at |
C20orf112 |
chromosome 20 open reading frame 112 |
20 |
-30494522 |
AL034550 |
140688 |
20q11.1-q11.23 |
Hs.516978 |
7 |
|
|
1552524_at |
-0.349 |
5.967 |
-2.339 |
3.337e-02 |
0.552 |
-3.570 |
ART5 |
ADP-ribosyltransferase 5 |
11 |
-3616311, -3616311 |
NM_053017 |
116969 |
11p15.4 |
Hs.125680 |
6 |
NAD(P)+-protein-arginine ADP-ribosyltransferase activity extracellular region protein amino acid ADP-ribosylation transferase activity, transferring glycosyl groups |
|
207817_at |
IFNW1 |
interferon, omega 1 |
9 |
-21130630 |
NM_002177 |
3467 |
9p22 |
Hs.73010 |
14 |
cytokine activity cytokine receptor binding extracellular region extracellular space defense response cell cycle arrest response to virus |
Cytokine-cytokine receptor interaction RIG-I-like receptor signaling pathway Jak-STAT signaling pathway |
1559977_a_at |
SLC25A34 |
solute carrier family 25, member 34 |
1 |
15935395 |
AL832282 |
284723 |
1p36.21 |
Hs.631867 |
3 |
binding mitochondrion mitochondrial inner membrane transport membrane integral to membrane |
|
235958_at |
PLA2G4F |
phospholipase A2, group IVF |
15 |
-40220688 |
AW299828 |
255189 |
15q15.1 |
Hs.231873 |
6 |
phospholipase A2 activity calcium ion binding cytoplasm lysosome cytosol metabolic process phospholipid catabolic process membrane lipid catabolic process hydrolase activity |
Fc gamma R-mediated phagocytosis |
217818_s_at |
ARPC4 |
actin related protein 2/3 complex, subunit 4, 20kDa |
3 |
9809226 |
NM_005718 |
10093 |
3p25.3 |
Hs.323342 |
16 |
cytoplasm cytoskeleton Arp2/3 protein complex actin filament polymerization protein binding, bridging cell projection actin nucleation actin filament binding |
Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
221047_s_at |
0.304 |
5.486 |
2.367 |
3.160e-02 |
0.544 |
-3.525 |
MARK1 |
MAP/microtubule affinity-regulating kinase 1 |
1 |
218768190 |
NM_018650 |
4139 |
1q41 |
Hs.497806 |
27 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm protein amino acid phosphorylation cytoskeleton organization protein kinase cascade microtubule cytoskeleton transferase activity |
|
207853_s_at |
SNCB |
synuclein, beta |
5 |
-175979815 |
NM_003085 |
6620 |
5q35 |
Hs.90297 |
25 |
phospholipase inhibitor activity cytoplasm mitochondrion synaptosome dopamine metabolic process negative regulation of neuron apoptosis |
|
235164_at |
ZNF25 |
zinc finger protein 25 |
10 |
-38278800 |
BG433539 |
219749 |
10p11.1 |
Hs.499429 |
8 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
241983_at |
PTPN2 |
protein tyrosine phosphatase, non-receptor type 2 |
18 |
-12783246, -12775482, -12775479 |
AV649337 |
5771 |
18p11.3-p11.2 |
Hs.654527 |
55 |
protein tyrosine phosphatase activity protein binding cytoplasm protein amino acid dephosphorylation hydrolase activity |
|
217754_at |
DDX56 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 |
7 |
-44571927 |
NM_019082 |
54606 |
7p13 |
Hs.654762 |
16 |
nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding nucleus nucleolus rRNA processing hydrolase activity identical protein binding |
|
221719_s_at |
LZTS1 |
leucine zipper, putative tumor suppressor 1 |
8 |
-20147956 |
AF123654 |
11178 |
8p22 |
Hs.521432 |
11 |
transcription factor activity protein binding nucleus cytoplasm Golgi apparatus plasma membrane transcription regulation of transcription, DNA-dependent cell cycle postsynaptic density cell junction cell projection dendritic spine synapse postsynaptic membrane |
|
204467_s_at |
SNCA |
synuclein, alpha (non A4 component of amyloid precursor) |
4 |
-90864273, -90864273, -90864273 |
NM_000345 |
6622 |
4q21 |
Hs.21374 |
498 |
positive regulation of receptor recycling nucleus cytoplasm cytosol plasma membrane cell cortex regulation of dopamine secretion actin cytoskeleton kinesin binding axon growth cone Hsp70 protein binding receptor internalization negative regulation of monooxygenase activity transferrin transmembrane transporter activity response to interferon-gamma negative regulation of histone acetylation histone binding alpha-tubulin binding dynein binding positive regulation of endocytosis tau protein binding synaptic vesicle endocytosis |
Alzheimer's disease Parkinson's disease |
221883_at |
PKNOX1 |
PBX/knotted 1 homeobox 1 |
21 |
43267711 |
AA133342 |
5316 |
21q22.3 |
Hs.431043 |
25 |
angiogenesis specific RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding nucleus transcription factor complex cytoplasm hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter protein heterodimerization activity |
|
210368_at |
PCDHGA8 |
protocadherin gamma subfamily A, 8 |
5 |
140751666, 140751666 |
AB002325 |
9708 |
5q31 |
Hs.368160 |
6 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion integral to membrane |
|
1558594_at |
C14orf176 |
chromosome 14 open reading frame 176 |
14 |
20636935 |
BQ649429 |
643382 |
14q11.2 |
|
|
membrane integral to membrane |
|
202942_at |
ETFB |
electron-transfer-flavoprotein, beta polypeptide |
19 |
-56540220, -56540220 |
NM_001985 |
2109 |
19q13.3 |
Hs.348531 |
16 |
mitochondrion mitochondrial matrix transport electron carrier activity electron transport chain |
|
1564537_a_at |
ASB10 |
ankyrin repeat and SOCS box-containing 10 |
7 |
-150503717, -150503717 |
AK055536 |
136371 |
7q36.1 |
Hs.647081 |
6 |
intracellular signaling cascade modification-dependent protein catabolic process |
|
230069_at |
SFXN1 |
sideroflexin 1 |
5 |
174838119 |
BF593817 |
94081 |
|
Hs.369440 |
18 |
iron ion binding protein binding mitochondrion mitochondrial inner membrane cation transport iron ion transport cation transmembrane transporter activity membrane integral to membrane erythrocyte differentiation |
|
202242_at |
TSPAN7 |
tetraspanin 7 |
X |
38305674 |
NM_004615 |
7102 |
Xp11.4 |
Hs.441664 |
18 |
plasma membrane integral to plasma membrane protein amino acid N-linked glycosylation |
|
204651_at |
NRF1 |
nuclear respiratory factor 1 |
7 |
129038790, 129057154 |
AW003022 |
4899 |
7q32 |
Hs.654363 |
47 |
DNA binding nucleus generation of precursor metabolites and energy regulation of transcription from RNA polymerase II promoter regulation of transcription |
Huntington's disease |
230882_at |
-0.271 |
3.380 |
-2.215 |
4.240e-02 |
0.575 |
-3.768 |
DLX6AS |
DLX6 antisense RNA (non-protein coding) |
7 |
-96435763 |
AA129217 |
285987 |
7q21.3 |
Hs.34969 |
4 |
|
|
225693_s_at |
CAMTA1 |
calmodulin binding transcription activator 1 |
1 |
6767970 |
AV756867 |
23261 |
1p36.31-p36.23 |
Hs.397705 |
12 |
nucleus cytoplasm regulation of transcription |
|
240070_at |
TIGIT |
T cell immunoreceptor with Ig and ITIM domains |
3 |
115495564 |
AW512550 |
201633 |
3q13.31 |
Hs.421750 |
4 |
protein binding plasma membrane cell surface integral to membrane negative regulation of interleukin-12 production positive regulation of interleukin-10 production negative regulation of T cell activation |
|
1552726_at |
ADAMTS17 |
ADAM metallopeptidase with thrombospondin type 1 motif, 17 |
15 |
-98329165 |
AA022668 |
170691 |
15q24 |
Hs.513200 |
5 |
metalloendopeptidase activity extracellular region proteinaceous extracellular matrix proteolysis peptidase activity zinc ion binding metal ion binding |
|
224861_at |
GNAQ |
guanine nucleotide binding protein (G protein), q polypeptide |
9 |
-79525010 |
AA628423 |
2776 |
9q21 |
Hs.269782 |
105 |
nucleotide binding skeletal system development regulation of action potential GTPase activity signal transducer activity protein binding GTP binding membrane fraction cytoplasm plasma membrane plasma membrane protein amino acid ADP-ribosylation signal transduction G-protein coupled receptor protein signaling pathway activation of adenylate cyclase activity by G-protein signaling pathway activation of phospholipase C activity glutamate signaling pathway heart development blood coagulation behavior post-embryonic development neuron remodeling guanyl nucleotide binding forebrain neuron development embryonic digit morphogenesis regulation of melanocyte differentiation pigmentation during development activation of phospholipase C activity by dopamine receptor signaling pathway |
Calcium signaling pathway Vascular smooth muscle contraction Gap junction Long-term potentiation Long-term depression GnRH signaling pathway Melanogenesis Alzheimer's disease Huntington's disease |
208677_s_at |
BSG |
basigin (Ok blood group) |
19 |
522324, 523536 |
AL550657 |
682 |
19p13.3 |
Hs.501293 |
124 |
Golgi membrane protein binding sugar binding mannose binding plasma membrane plasma membrane cell surface receptor linked signal transduction integral to membrane melanosome |
|
225740_x_at |
MDM4 |
Mdm4 p53 binding protein homolog (mouse) |
1 |
202752133 |
AA961420 |
4194 |
1q32 |
Hs.497492 |
68 |
negative regulation of transcription from RNA polymerase II promoter protein binding intracellular nucleus protein complex assembly apoptosis zinc ion binding negative regulation of cell proliferation negative regulation of protein catabolic process G0 to G1 transition metal ion binding protein stabilization |
p53 signaling pathway |
233164_x_at |
RHBDD1 |
rhomboid domain containing 1 |
2 |
227409016 |
AK026955 |
84236 |
2q36.3 |
Hs.471514 |
7 |
peptidase activity serine-type peptidase activity membrane integral to membrane |
|
210015_s_at |
-0.283 |
3.338 |
-2.817 |
1.288e-02 |
0.432 |
-2.771 |
MAP2 |
microtubule-associated protein 2 |
2 |
209997015, 210152647 |
U89330 |
4133 |
2q34-q35 |
Hs.368281 |
58 |
structural molecule activity calmodulin binding cytoplasm cytoskeleton microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
239173_at |
INADL |
InaD-like (Drosophila) |
1 |
61980736 |
AI697184 |
10207 |
1p31.3 |
Hs.478125 |
24 |
protein binding cellular_component plasma membrane tight junction intracellular signaling cascade apical plasma membrane cell junction |
Tight junction |
222133_s_at |
PHF20L1 |
PHD finger protein 20-like 1 |
8 |
133856785, 133856785, 133856785 |
AK022280 |
51105 |
8q24.22 |
Hs.304362 |
4 |
nucleic acid binding protein binding zinc ion binding metal ion binding |
|
218821_at |
NPEPL1 |
aminopeptidase-like 1 |
20 |
56701267 |
AL139349 |
79716 |
20q13.32 |
Hs.554211 Hs.654868 |
7 |
aminopeptidase activity intracellular proteolysis peptidase activity zinc ion binding manganese ion binding metal ion binding |
|
1566140_at |
HOPX |
HOP homeobox |
4 |
-57208910, -57208910 |
AK096707 |
84525 |
4q11-q12 |
Hs.654864 |
25 |
negative regulation of transcription from RNA polymerase II promoter trophectodermal cell differentiation transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent multicellular organismal development heart development regulation of heart contraction transcription repressor activity histone deacetylation positive regulation of skeletal muscle regeneration sequence-specific DNA binding negative regulation of cell differentiation lung alveolus development positive regulation of striated muscle cell differentiation |
|
211628_x_at |
FTHP1 |
ferritin, heavy polypeptide pseudogene 1 |
6 |
|
J04755 |
2509 |
6p21.3-p12 |
Hs.453583 |
1 |
|
|
221289_at |
DLX6 |
distal-less homeobox 6 |
7 |
96473225 |
NM_005222 |
1750 |
7q22 |
Hs.249196 |
11 |
skeletal system development transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development nervous system development embryonic limb morphogenesis epithelial cell differentiation inner ear morphogenesis sequence-specific DNA binding anatomical structure formation involved in morphogenesis positive regulation of epithelial cell proliferation |
|
211673_s_at |
MOCS1 |
molybdenum cofactor synthesis 1 |
6 |
-39980023, -39980023 |
AF034374 |
4337 |
6p21.3 |
Hs.718492 |
19 |
nucleotide binding catalytic activity iron ion binding GTP binding nucleus Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor biosynthetic process metabolic process molybdopterin synthase complex molybdenum ion binding metal ion binding 4 iron, 4 sulfur cluster binding |
|
207660_at |
-0.687 |
4.226 |
-4.479 |
4.270e-04 |
0.193 |
0.114 |
DMD |
dystrophin |
X |
-31106232, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265, -31047265 |
NM_004019 |
1756 |
Xp21.2 |
Hs.495912 |
240 |
actin binding structural constituent of cytoskeleton calcium ion binding protein binding cytoplasm cytoskeleton muscle organ development zinc ion binding structural constituent of muscle structural constituent of muscle cell surface dystrophin-associated glycoprotein complex sarcolemma costamere peptide biosynthetic process nitric-oxide synthase binding |
Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
216399_s_at |
SCAPER |
S-phase cyclin A-associated protein in the ER |
15 |
-74427583, -74427583 |
AK025663 |
49855 |
15q24 |
Hs.458986 |
7 |
intracellular nucleus endoplasmic reticulum zinc ion binding metal ion binding |
|
1552695_a_at |
-0.351 |
4.130 |
-2.516 |
2.358e-02 |
0.508 |
-3.280 |
SLC2A13 |
solute carrier family 2 (facilitated glucose transporter), member 13 |
12 |
-38435091 |
NM_052885 |
114134 |
12q12 |
Hs.558595 |
5 |
transporter activity membrane integral to membrane substrate-specific transmembrane transporter activity transmembrane transport |
|
205595_at |
DSG3 |
desmoglein 3 (pemphigus vulgaris antigen) |
18 |
27281729 |
NM_001944 |
1830 |
18q12.1-q12.2 |
Hs.1925 |
51 |
calcium ion binding protein binding cytosol plasma membrane plasma membrane cell adhesion homophilic cell adhesion integral to membrane cell junction desmosome |
|
1559292_s_at |
NCRNA00032 |
non-protein coding RNA 32 |
9 |
-27235683 |
AF507950 |
158035 |
9p21 |
Hs.201554 |
1 |
|
|
200876_s_at |
PSMB1 |
proteasome (prosome, macropain) subunit, beta type, 1 |
6 |
-170686129 |
NM_002793 |
5689 |
6q27 |
Hs.352768 |
47 |
threonine-type endopeptidase activity protein binding nucleus cytoplasm cytosol proteasome core complex peptidase activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle proteolysis involved in cellular protein catabolic process |
Proteasome |
219327_s_at |
GPRC5C |
G protein-coupled receptor, family C, group 5, member C |
17 |
69939261, 69941430 |
NM_022036 |
55890 |
17q25 |
Hs.446438 |
10 |
receptor activity G-protein coupled receptor activity protein binding mitochondrion plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway cytoplasmic vesicle |
|
225953_at |
RPRD1A |
regulation of nuclear pre-mRNA domain containing 1A |
18 |
-31823789 |
AI684281 |
55197 |
18q12.2 |
Hs.464912 |
3 |
|
|
236726_at |
RGS6 |
regulator of G-protein signaling 6 |
14 |
71469538 |
H41121 |
9628 |
14q24.3 |
Hs.509872 |
13 |
signal transducer activity GTPase activator activity cellular_component cytoplasm heterotrimeric G-protein complex intracellular signaling cascade regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction membrane |
|
244071_at |
FBLL1 |
fibrillarin-like 1 |
5 |
167889159 |
AA868464 |
345630 |
5q34 |
Hs.166262 |
|
RNA binding nucleus nucleolus rRNA processing methyltransferase activity transferase activity ribonucleoprotein complex |
|
217831_s_at |
NSFL1C |
NSFL1 (p97) cofactor (p47) |
20 |
-1370810 |
NM_016143 |
55968 |
20p13 |
Hs.12865 |
20 |
protein binding nucleus Golgi apparatus Golgi stack lipid binding |
|
211748_x_at |
PTGDS |
prostaglandin D2 synthase 21kDa (brain) |
9 |
138991776 |
BC005939 |
5730 |
9q34.2-q34.3 |
Hs.446429 |
63 |
prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm |
Arachidonic acid metabolism Metabolic pathways |
206801_at |
NPPB |
natriuretic peptide precursor B |
1 |
-11840107 |
NM_002521 |
4879 |
1p36.2 |
Hs.219140 |
228 |
extracellular region extracellular space cell surface receptor linked signal transduction regulation of blood pressure diuretic hormone activity negative regulation of angiogenesis diuresis natriuresis negative regulation of cell growth regulation of vasodilation regulation of vascular permeability regulation of blood vessel size |
|
218937_at |
ZNF434 |
zinc finger protein 434 |
16 |
-3372085 |
NM_017810 |
54925 |
16p13.3 |
Hs.592078 |
3 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
208328_s_at |
MEF2A |
myocyte enhancer factor 2A |
15 |
97923655, 97990705 |
NM_005587 |
4205 |
15q26 |
Hs.268675 |
77 |
transcription factor activity nucleus regulation of transcription, DNA-dependent apoptosis multicellular organismal development nervous system development muscle organ development cell differentiation sequence-specific DNA binding |
|
210266_s_at |
0.337 |
7.708 |
2.438 |
2.749e-02 |
0.526 |
-3.409 |
TRIM33 |
tripartite motif-containing 33 |
1 |
-114736921 |
AF220137 |
51592 |
1p13.1 |
Hs.26837 |
12 |
DNA binding protein binding intracellular nucleus zinc ion binding negative regulation of transcription protein ubiquitination ligase activity regulation of transforming growth factor beta receptor signaling pathway modification-dependent protein catabolic process negative regulation of BMP signaling pathway metal ion binding co-SMAD binding R-SMAD binding |
|
222522_x_at |
MRPS10 |
mitochondrial ribosomal protein S10 |
6 |
-42282516 |
BG393476 |
55173 |
6p21.1 |
Hs.380887 Hs.669022 |
8 |
molecular_function structural constituent of ribosome intracellular mitochondrion ribosome translation biological_process |
|
213358_at |
KIAA0802 |
KIAA0802 |
18 |
8707368 |
AB018345 |
23255 |
18p11.22 |
Hs.650822 |
10 |
|
|
211285_s_at |
UBE3A |
ubiquitin protein ligase E3A |
15 |
-23133488, -23133488, -23133488 |
U84404 |
7337 |
15q11-q13 |
Hs.598862 |
76 |
ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms |
Ubiquitin mediated proteolysis |
218499_at |
RP6-213H19.1 |
serine/threonine protein kinase MST4 |
X |
130984925, 130985316 |
NM_016542 |
51765 |
Xq26.2 |
Hs.444247 |
16 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus protein amino acid phosphorylation transferase activity identical protein binding regulation of apoptosis |
|
225611_at |
MAST4 |
microtubule associated serine/threonine kinase family member 4 |
5 |
65927931, 66160359 |
AI922968 |
375449 |
5q12.3 |
Hs.595458 |
5 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
227792_at |
0.317 |
7.361 |
2.539 |
2.250e-02 |
0.500 |
-3.241 |
ITPRIPL2 |
inositol 1,4,5-triphosphate receptor interacting protein-like 2 |
16 |
19032754 |
AA490685 |
162073 |
16p12.3 |
Hs.530899 Hs.648523 |
3 |
membrane integral to membrane |
|
217710_x_at |
ITPK1 |
inositol 1,3,4-triphosphate 5/6 kinase |
14 |
-92475821, -92473011 |
AI075181 |
3705 |
14q31 |
Hs.308122 |
12 |
nucleotide binding magnesium ion binding ATP binding intracellular signal transduction kinase activity transferase activity hydrolase activity isomerase activity inositol trisphosphate metabolic process inositol-1,3,4-trisphosphate 5/6-kinase activity inositol tetrakisphosphate 1-kinase activity |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system |
218728_s_at |
CNIH4 |
cornichon homolog 4 (Drosophila) |
1 |
222611217 |
NM_014184 |
29097 |
1q42.11 |
Hs.195403 Hs.445890 |
11 |
protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane |
|
219039_at |
SEMA4C |
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
2 |
-96889199 |
NM_017789 |
54910 |
2q11.2 |
Hs.516220 |
9 |
receptor activity protein binding multicellular organismal development nervous system development membrane integral to membrane cell differentiation |
Axon guidance |
238320_at |
NEAT1 |
nuclear paraspeckle assembly transcript 1 (non-protein coding) |
11 |
64946844, 64946844 |
AV659198 |
283131 |
11q13.1 |
Hs.523789 Hs.648467 |
6 |
|
|
213512_at |
C14orf79 |
chromosome 14 open reading frame 79 |
14 |
104523660 |
BF109941 |
122616 |
14q32.33 |
Hs.27183 |
7 |
|
|
217607_x_at |
EIF4G2 |
eukaryotic translation initiation factor 4 gamma, 2 |
11 |
-10775168 |
AA733172 |
1982 |
11p15 |
Hs.183684 |
39 |
translation initiation factor activity protein binding regulation of translational initiation cell cycle arrest cell death RNA metabolic process eukaryotic translation initiation factor 4F complex |
|
231967_at |
PHF20L1 |
PHD finger protein 20-like 1 |
8 |
133856785, 133856785, 133856785 |
AI913146 |
51105 |
8q24.22 |
Hs.304362 |
4 |
nucleic acid binding protein binding zinc ion binding metal ion binding |
|
222587_s_at |
GALNT7 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) |
4 |
174326478 |
BF699855 |
51809 |
4q31.1 |
Hs.548088 |
7 |
polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus carbohydrate metabolic process protein amino acid O-linked glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding |
O-Glycan biosynthesis Metabolic pathways |
219714_s_at |
CACNA2D3 |
calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
3 |
54131732 |
NM_018398 |
55799 |
3p21.1 |
Hs.656687 |
9 |
voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane |
MAPK signaling pathway Cardiac muscle contraction Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
210251_s_at |
RUFY3 |
RUN and FYVE domain containing 3 |
4 |
71789517, 71806559, 71806559 |
AF112221 |
22902 |
4q13.3 |
Hs.713172 |
8 |
multicellular organismal development nervous system development cell differentiation filopodium growth cone negative regulation of axonogenesis |
|
219699_at |
LGI2 |
leucine-rich repeat LGI family, member 2 |
4 |
-24609568 |
NM_018176 |
55203 |
4p15.2 |
Hs.12488 |
11 |
protein binding extracellular region |
|
211184_s_at |
-0.257 |
4.467 |
-2.404 |
2.941e-02 |
0.536 |
-3.465 |
USH1C |
Usher syndrome 1C (autosomal recessive, severe) |
11 |
-17472018 |
AB006955 |
10083 |
11p15.1-p14 |
Hs.502072 |
32 |
G2/M transition of mitotic cell cycle protein binding cytoplasm sensory perception of sound stereocilium apical part of cell photoreceptor cell maintenance response to stimulus equilibrioception |
|
207929_at |
GRPR |
gastrin-releasing peptide receptor |
X |
16051344 |
NM_005314 |
2925 |
Xp22.2-p22.13 |
Hs.567282 |
36 |
receptor activity bombesin receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway peptide receptor activity, G-protein coupled regulation of cell proliferation |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
213258_at |
0.655 |
7.151 |
3.785 |
1.758e-03 |
0.268 |
-1.078 |
TFPI |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
2 |
-188051550, -188037202 |
BF511231 |
7035 |
2q32 |
Hs.516578 |
118 |
serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway |
Complement and coagulation cascades |
223899_at |
PBRM1 |
polybromo 1 |
3 |
-52554407, -52554407 |
AF225870 |
55193 |
3p21 |
Hs.189920 |
19 |
nuclear chromosome DNA binding chromatin binding protein binding nucleus chromatin remodeling mitosis regulation of transcription |
|
227954_at |
ITPRIPL2 |
inositol 1,4,5-triphosphate receptor interacting protein-like 2 |
16 |
19032754 |
AI458417 |
162073 |
16p12.3 |
Hs.530899 Hs.648523 |
3 |
membrane integral to membrane |
|
201200_at |
0.560 |
8.802 |
2.955 |
9.722e-03 |
0.407 |
-2.532 |
CREG1 |
cellular repressor of E1A-stimulated genes 1 |
1 |
-165776874 |
NM_003851 |
8804 |
1q24 |
Hs.5710 |
16 |
RNA polymerase II transcription factor activity transcription corepressor activity extracellular region regulation of transcription from RNA polymerase II promoter multicellular organismal development cell proliferation regulation of growth |
|
201587_s_at |
0.535 |
7.863 |
2.619 |
1.920e-02 |
0.489 |
-3.108 |
IRAK1 |
interleukin-1 receptor-associated kinase 1 |
X |
-152929150 |
NM_001569 |
3654 |
Xq28 |
Hs.522819 |
107 |
nucleotide binding magnesium ion binding regulation of cytokine-mediated signaling pathway MyD88-dependent toll-like receptor signaling pathway protein serine/threonine kinase activity NF-kappaB-inducing kinase activity ATP binding cytosol signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway activation of NF-kappaB-inducing kinase activity transcription activator activity transferase activity lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity response to lipopolysaccharide toll-like receptor 2 signaling pathway protein homodimerization activity interleukin-1 receptor complex positive regulation of transcription protein amino acid autophosphorylation protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity protein oligomerization interleukin-1-mediated signaling pathway response to interleukin-1 |
Apoptosis Toll-like receptor signaling pathway Neurotrophin signaling pathway |
224998_at |
0.248 |
5.929 |
2.466 |
2.600e-02 |
0.518 |
-3.362 |
CMTM4 |
CKLF-like MARVEL transmembrane domain containing 4 |
16 |
-65206153 |
AK000855 |
146223 |
16q21-q22.1 |
Hs.643961 |
3 |
cytokine activity extracellular space chemotaxis membrane integral to membrane |
|
208643_s_at |
XRCC5 |
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
2 |
216682264 |
J04977 |
7520 |
2q35 |
Hs.388739 |
148 |
nucleotide binding telomere maintenance nuclear telomere cap complex DNA binding double-stranded telomeric DNA binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus nucleoplasm chromosome double-strand break repair via nonhomologous end joining response to DNA damage stimulus protein C-terminus binding promoter binding hydrolase activity provirus integration initiation of viral infection |
Non-homologous end-joining |
228494_at |
PPP1R9A |
protein phosphatase 1, regulatory (inhibitor) subunit 9A |
7 |
94374884 |
AI888150 |
55607 |
7q21.3 |
Hs.21816 |
12 |
actin binding protein binding cytoplasm cytoskeleton actin filament organization multicellular organismal development nervous system development synaptosome cell junction cell differentiation filopodium cortical actin cytoskeleton dendritic spine synapse |
|
240878_at |
SPEM1 |
spermatid maturation 1 |
17 |
7264402 |
AW172597 |
374768 |
17p13.1 |
Hs.710599 |
3 |
cytoplasm multicellular organismal development spermatogenesis membrane integral to membrane cell differentiation |
|
208119_s_at |
ZNF93 |
zinc finger protein 93 |
19 |
19872786 |
NM_031218 |
81931 |
19p12 |
Hs.301059 |
5 |
transcription factor activity intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
210583_at |
-0.212 |
5.302 |
-2.177 |
4.558e-02 |
0.581 |
-3.828 |
POLDIP3 |
polymerase (DNA-directed), delta interacting protein 3 |
22 |
-41309670 |
AB055760 |
84271 |
22q13.2 |
Hs.505802 |
11 |
nucleotide binding RNA binding protein binding nucleus |
|
234511_at |
ANKRD60 |
ankyrin repeat domain 60 |
20 |
|
AL354776 |
140731 |
20q13.32 |
|
1 |
|
|
210331_at |
HECW1 |
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
7 |
43118722 |
AB048365 |
23072 |
7p14.1-p13 |
Hs.164453 |
8 |
protein binding intracellular cytoplasm protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process |
|
226982_at |
0.490 |
5.535 |
2.312 |
3.516e-02 |
0.555 |
-3.614 |
ELL2 |
elongation factor, RNA polymerase II, 2 |
5 |
-95246557 |
AI745624 |
22936 |
5q15 |
Hs.192221 Hs.708710 |
6 |
RNA polymerase II transcription factor activity nucleus RNA elongation from RNA polymerase II promoter transcription elongation factor complex RNA polymerase II transcription elongation factor activity regulation of transcription |
|
203656_at |
FIG4 |
FIG4 homolog (S. cerevisiae) |
6 |
110119116 |
NM_014845 |
9896 |
6q21 |
Hs.529959 |
14 |
protein binding endosome cell death endosome membrane membrane hydrolase activity |
|
232293_at |
LCORL |
ligand dependent nuclear receptor corepressor-like |
4 |
-17453941 |
AL133031 |
254251 |
4p15.31 |
Hs.446201 Hs.661849 Hs.677572 |
9 |
DNA binding RNA polymerase II transcription factor activity nucleus transcription from RNA polymerase II promoter regulation of transcription |
|
213037_x_at |
STAU1 |
staufen, RNA binding protein, homolog 1 (Drosophila) |
20 |
-47163282 |
AJ132258 |
6780 |
20q13.1 |
Hs.596704 |
26 |
double-stranded RNA binding protein binding intracellular rough endoplasmic reticulum microtubule associated complex intracellular mRNA localization ribonucleoprotein complex |
|
201992_s_at |
KIF5B |
kinesin family member 5B |
10 |
-32337943 |
NM_004521 |
3799 |
10pter-q22.1 |
Hs.644646 |
36 |
nucleotide binding microtubule motor activity protein binding ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule-based movement cytoplasm organization microtubule binding ciliary rootlet neuron projection membrane-bounded organelle vesicle transport along microtubule perinuclear region of cytoplasm |
|
223139_s_at |
DHX36 |
DEAH (Asp-Glu-Ala-His) box polypeptide 36 |
3 |
-155476150 |
BE501133 |
170506 |
3p13-q23 |
Hs.446270 |
13 |
nucleotide binding nucleic acid binding helicase activity protein binding ATP binding nucleus cytoplasm ATP-dependent helicase activity hydrolase activity |
|
225589_at |
SH3RF1 |
SH3 domain containing ring finger 1 |
4 |
-170251981 |
AB040927 |
57630 |
4q32.3-q33 |
Hs.301804 |
9 |
protein binding cytoplasm Golgi apparatus zinc ion binding ligase activity lamellipodium metal ion binding perinuclear region of cytoplasm |
|
211198_s_at |
ICOSLG |
inducible T-cell co-stimulator ligand |
21 |
-44471149 |
AF289028 |
23308 |
21q22.3 |
Hs.14155 |
29 |
receptor binding defense response immune response hyperosmotic response signal transduction membrane integral to membrane positive regulation of activated T cell proliferation T cell activation B cell activation |
Cell adhesion molecules (CAMs) |
224657_at |
ERRFI1 |
ERBB receptor feedback inhibitor 1 |
1 |
-7994366 |
AL034417 |
54206 |
1p36 |
Hs.605445 |
26 |
Rho GTPase activator activity protein binding cytoplasm response to stress |
|
212973_at |
-0.173 |
8.276 |
-2.222 |
4.189e-02 |
0.574 |
-3.758 |
RPIA |
ribose 5-phosphate isomerase A |
2 |
88772290 |
AI692341 |
22934 |
2p11.2 |
Hs.469264 |
7 |
ribose-5-phosphate isomerase activity ribose-5-phosphate isomerase activity intracellular cytosol pentose-phosphate shunt, non-oxidative branch isomerase activity |
Pentose phosphate pathway Carbon fixation in photosynthetic organisms Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways |
206218_at |
MAGEB2 |
melanoma antigen family B, 2 |
X |
30143595 |
NM_002364 |
4113 |
Xp21.3 |
Hs.113824 |
12 |
protein binding |
|
211370_s_at |
0.487 |
6.224 |
2.517 |
2.349e-02 |
0.507 |
-3.277 |
MAP2K5 |
mitogen-activated protein kinase kinase 5 |
15 |
65622074 |
U71088 |
5607 |
15q23 |
Hs.114198 |
29 |
MAPKKK cascade nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding spindle protein amino acid phosphorylation signal transduction heart development transferase activity |
MAPK signaling pathway Gap junction Neurotrophin signaling pathway |
206698_at |
XK |
X-linked Kx blood group (McLeod syndrome) |
X |
37430051 |
NM_021083 |
7504 |
Xp21.1 |
Hs.78919 |
24 |
transporter activity protein binding transport amino acid transport membrane integral to membrane |
|
233188_at |
GALNTL4 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 |
11 |
-11248996 |
AF131852 |
374378 |
11p15.3 |
Hs.655152 |
6 |
polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding |
O-Glycan biosynthesis Metabolic pathways |
221571_at |
TRAF3 |
TNF receptor-associated factor 3 |
14 |
102313568 |
AI721219 |
7187 |
14q32.32 |
Hs.510528 |
99 |
signal transducer activity protein binding cytoplasm induction of apoptosis signal transduction zinc ion binding regulation of apoptosis metal ion binding |
Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway Pathways in cancer Small cell lung cancer |
211844_s_at |
NRP2 |
neuropilin 2 |
2 |
206255468, 206255468, 206255468 |
AF022859 |
8828 |
2q33.3 |
Hs.471200 |
44 |
receptor activity vascular endothelial growth factor receptor activity membrane fraction plasma membrane cell adhesion multicellular organismal development nervous system development axon guidance integral to membrane cell differentiation |
|
241727_x_at |
DHFRL1 |
dihydrofolate reductase-like 1 |
3 |
-95259455 |
AA578546 |
200895 |
3q11.1 |
Hs.718516 |
4 |
dihydrofolate reductase activity glycine biosynthetic process nucleotide biosynthetic process NADP or NADPH binding |
|
212681_at |
0.792 |
4.830 |
2.195 |
4.411e-02 |
0.579 |
-3.801 |
EPB41L3 |
erythrocyte membrane protein band 4.1-like 3 |
18 |
-5382387 |
AI770004 |
23136 |
18p11.32 |
Hs.213394 |
39 |
actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization |
Tight junction |
219922_s_at |
LTBP3 |
latent transforming growth factor beta binding protein 3 |
11 |
-65062605 |
NM_021070 |
4054 |
11q13.1 |
Hs.289019 |
19 |
binding calcium ion binding extracellular region growth factor binding |
|
206843_at |
CRYBA4 |
crystallin, beta A4 |
22 |
25347927 |
NM_001886 |
1413 |
22q11.2-q13.1 22q12.1 |
Hs.57690 |
13 |
molecular_function structural constituent of eye lens soluble fraction visual perception visual perception camera-type eye development |
|
1556049_at |
RTN4 |
reticulon 4 |
2 |
-55052830, -55052830, -55052830 |
CA428769 |
57142 |
2p16.3 |
Hs.704007 |
73 |
protein binding nuclear envelope endoplasmic reticulum membrane integral to membrane negative regulation of anti-apoptosis integral to endoplasmic reticulum membrane regulation of cell migration negative regulation of axon extension regulation of apoptosis |
|
217945_at |
BTBD1 |
BTB (POZ) domain containing 1 |
15 |
-81476184 |
NM_025238 |
53339 |
15q24 |
Hs.459149 |
15 |
cytoplasmic mRNA processing body protein binding cellular_component cytoplasm biological_process modification-dependent protein catabolic process protein complex |
|
227768_at |
ZNF407 |
zinc finger protein 407 |
18 |
70471906, 70471906, 70471906 |
AB051490 |
55628 |
18q23 |
Hs.536490 |
3 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
226999_at |
RNPC3 |
RNA-binding region (RNP1, RRM) containing 3 |
1 |
103841165 |
AL137730 |
55599 |
1p21 |
Hs.632423 Hs.632430 |
7 |
nucleotide binding RNA binding nucleus U12-type spliceosomal complex mRNA processing RNA splicing |
|
1569323_at |
PTPRG |
protein tyrosine phosphatase, receptor type, G |
3 |
61522282 |
BU853579 |
5793 |
3p21-p14 |
Hs.595541 Hs.654488 |
19 |
transmembrane receptor protein tyrosine phosphatase activity integral to plasma membrane protein amino acid dephosphorylation transmembrane receptor protein tyrosine kinase signaling pathway membrane hydrolase activity identical protein binding |
|
209265_s_at |
METTL3 |
methyltransferase like 3 |
14 |
-21036121 |
BC001650 |
56339 |
14q11.1 |
Hs.168799 |
8 |
RNA methylation RNA binding nucleus nucleoplasm nucleobase, nucleoside, nucleotide and nucleic acid metabolic process methyltransferase activity mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity nuclear speck transferase activity |
|
1561355_at |
LOC692247 |
hypothetical locus LOC692247 |
11 |
|
AA975897 |
692247 |
11p15.5 |
Hs.560022 |
2 |
|
|
1556072_at |
C22orf37 |
chromosome 22 open reading frame 37 |
22 |
|
AK097861 |
200298 |
22q11.21 |
Hs.517397 |
1 |
|
|
215938_s_at |
PLA2G6 |
phospholipase A2, group VI (cytosolic, calcium-independent) |
22 |
-36837447 |
AK001290 |
8398 |
22q13.1 |
Hs.170479 |
48 |
nucleus cytoplasm centrosome phospholipid metabolic process metabolic process cell death membrane lipid catabolic process hydrolase activity calcium-independent phospholipase A2 activity |
Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Vascular smooth muscle contraction VEGF signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Long-term depression GnRH signaling pathway |
1554994_at |
-0.249 |
2.521 |
-2.170 |
4.624e-02 |
0.582 |
-3.840 |
RAG1 |
recombination activating gene 1 |
11 |
36546138 |
BC037344 |
5896 |
11p13 |
Hs.677010 Hs.73958 |
58 |
DNA binding endonuclease activity protein binding intracellular nucleus DNA recombination immune response zinc ion binding death hydrolase activity B cell differentiation T cell differentiation in the thymus V(D)J recombination negative regulation of caspase activity metal ion binding negative regulation of thymocyte apoptosis |
Primary immunodeficiency |
227405_s_at |
FZD8 |
frizzled homolog 8 (Drosophila) |
10 |
-35967182 |
AW340311 |
8325 |
10p11.21 |
Hs.302634 |
14 |
non-G-protein coupled 7TM receptor activity G-protein coupled receptor activity G-protein coupled receptor protein signaling pathway multicellular organismal development membrane integral to membrane Wnt receptor signaling pathway Wnt-protein binding Wnt receptor activity |
Wnt signaling pathway Melanogenesis Pathways in cancer Colorectal cancer Basal cell carcinoma |
202578_s_at |
DDX19A |
DEAD (Asp-Glu-Ala-As) box polypeptide 19A |
16 |
68938324 |
NM_018332 |
55308 |
16q22.1 |
Hs.656037 |
5 |
nucleotide binding RNA binding helicase activity ATP binding nucleus nuclear pore cytoplasm ATP-dependent helicase activity protein transport membrane hydrolase activity mRNA transport intracellular protein transmembrane transport |
|
216511_s_at |
0.275 |
5.301 |
2.612 |
1.945e-02 |
0.489 |
-3.119 |
TCF7L2 |
transcription factor 7-like 2 (T-cell specific, HMG-box) |
10 |
114699998 |
AJ270770 |
6934 |
10q25.3 |
Hs.593995 |
246 |
blood vessel development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter anti-apoptosis cell cycle arrest beta-catenin binding transcription factor binding cell proliferation positive regulation of specific transcription from RNA polymerase II promoter positive regulation of heparan sulfate proteoglycan biosynthetic process specific transcriptional repressor activity protein kinase binding pancreas development positive regulation of insulin secretion regulation of hormone metabolic process glucose homeostasis fat cell differentiation regulation of transcription myoblast cell fate commitment Wnt receptor signaling pathway through beta-catenin beta-catenin-TCF7L2 complex |
Wnt signaling pathway Adherens junction Melanogenesis Pathways in cancer Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
213906_at |
MYBL1 |
v-myb myeloblastosis viral oncogene homolog (avian)-like 1 |
8 |
-67636963 |
AW592266 |
4603 |
8q22 |
Hs.445898 |
8 |
DNA binding nucleus nucleolus regulation of transcription, DNA-dependent transcription activator activity |
|
222561_at |
LANCL2 |
LanC lantibiotic synthetase component C-like 2 (bacterial) |
7 |
55400634 |
AJ278245 |
55915 |
7q31.1-q31.33 |
Hs.595384 Hs.655117 |
9 |
catalytic activity ATP binding GTP binding nucleus cytoplasm cytosol plasma membrane negative regulation of transcription |
|
235908_at |
MMP11 |
matrix metallopeptidase 11 (stromelysin 3) |
22 |
22445035 |
AW511464 |
4320 |
22q11.2 22q11.23 |
Hs.143751 |
30 |
metalloendopeptidase activity calcium ion binding extracellular region proteinaceous extracellular matrix proteolysis multicellular organismal development peptidase activity zinc ion binding collagen catabolic process |
|
228298_at |
-0.301 |
4.394 |
-2.799 |
1.334e-02 |
0.435 |
-2.800 |
FAM113B |
family with sequence similarity 113, member B |
12 |
45896318 |
BF056901 |
91523 |
12q13.11 |
Hs.560100 |
1 |
|
|
214574_x_at |
LST1 |
leukocyte specific transcript 1 |
6 |
31661949, 31662603, 3000093, 3000747, 2801557, 2802211 |
NM_007161 |
7940 |
6p21.3 |
Hs.436066 |
20 |
cell morphogenesis molecular_function protein binding cytoplasm Golgi apparatus immune response regulation of cell shape anatomical structure morphogenesis membrane integral to membrane dendrite development negative regulation of lymphocyte proliferation |
|
204706_at |
-0.283 |
6.578 |
-2.586 |
2.051e-02 |
0.496 |
-3.163 |
INPP5E |
inositol polyphosphate-5-phosphatase, 72 kDa |
9 |
-138442892 |
NM_019892 |
56623 |
9q34.3 |
Hs.120998 |
5 |
Golgi membrane inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity cellular_component Golgi apparatus lipid metabolic process biological_process membrane hydrolase activity |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system |
220266_s_at |
KLF4 |
Kruppel-like factor 4 (gut) |
9 |
-109286953 |
NM_004235 |
9314 |
9q31 |
Hs.376206 |
66 |
transcription factor activity intracellular nucleus nucleolus mesodermal cell fate determination zinc ion binding negative regulation of cell proliferation transcription activator activity transcription repressor activity regulation of transcription negative regulation of transcription, DNA-dependent metal ion binding |
|
1563405_at |
ATP4B |
ATPase, H+/K+ exchanging, beta polypeptide |
13 |
-113351122 |
BC042846 |
496 |
13q34 |
Hs.434202 |
17 |
sodium:potassium-exchanging ATPase activity ATP biosynthetic process ion transport potassium ion transport sodium ion transport hydrogen:potassium-exchanging ATPase activity proton transport membrane integral to membrane potassium ion binding |
Oxidative phosphorylation |
216129_at |
ATP9A |
ATPase, class II, type 9A |
20 |
-49646720 |
AL117659 |
10079 |
20q13.2 |
Hs.719117 |
6 |
nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding ATP biosynthetic process metabolic process ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
|
216838_at |
LOC92249 |
hypothetical LOC92249 |
X |
-62563163 |
AK023798 |
92249 |
Xq11.1 |
Hs.31532 Hs.708316 |
1 |
|
|
226502_at |
ELMOD2 |
ELMO/CED-12 domain containing 2 |
4 |
141664801 |
BG477315 |
255520 |
4q31.1 |
Hs.450105 |
6 |
cytoskeleton phagocytosis |
|
239493_at |
RPL7 |
ribosomal protein L7 |
8 |
-74365427 |
AI984074 |
6129 |
8q21.11 |
Hs.421257 Hs.571841 |
23 |
DNA binding mRNA binding structural constituent of ribosome intracellular cytosol ribosome rRNA processing translational elongation cytosolic large ribosomal subunit transcription regulator activity ribosomal large subunit biogenesis protein homodimerization activity |
Ribosome |
209723_at |
SERPINB9 |
serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
6 |
-2832504 |
BC002538 |
5272 |
6p25 |
Hs.104879 |
27 |
serine-type endopeptidase inhibitor activity protein binding cytoplasm cytosol anti-apoptosis signal transduction peptidase inhibitor activity |
|
223518_at |
DFFA |
DNA fragmentation factor, 45kDa, alpha polypeptide |
1 |
-10443189 |
AF087573 |
1676 |
1p36.3-p36.2 |
Hs.484782 |
44 |
caspase-activated deoxyribonuclease activity intracellular nucleus nucleoplasm cytoplasm cytosol DNA fragmentation involved in apoptosis intracellular signaling cascade identical protein binding negative regulation of apoptosis |
Apoptosis |
203232_s_at |
ATXN1 |
ataxin 1 |
6 |
-16407321 |
NM_000332 |
6310 |
6p23 |
Hs.434961 Hs.712106 |
65 |
RNA binding nucleus nucleoplasm nucleolus cytoplasm RNA processing protein C-terminus binding cell death poly(U) RNA binding adult locomotory behavior visual learning nuclear matrix negative regulation of transcription transcription repressor activity poly(G) RNA binding nuclear RNA export factor complex negative regulation of phosphorylation nuclear inclusion body identical protein binding negative regulation of insulin-like growth factor receptor signaling pathway protein self-association positive regulation of transcription from RNA polymerase II promoter nuclear export regulation of excitatory postsynaptic membrane potential |
|
227863_at |
0.536 |
4.685 |
2.521 |
2.335e-02 |
0.507 |
-3.272 |
CTSD |
cathepsin D |
11 |
-1730560 |
AV706254 |
1509 |
11p15.5 |
Hs.121575 Hs.654447 |
140 |
autophagic vacuole formation aspartic-type endopeptidase activity extracellular region mitochondrion lysosome proteolysis peptidase activity melanosome |
Lysosome |
216699_s_at |
KLK1 |
kallikrein 1 |
19 |
-56014215 |
L10038 |
3816 |
19q13.3 |
Hs.123107 |
74 |
serine-type endopeptidase activity proteolysis peptidase activity |
|
211121_s_at |
DOK1 |
docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
2 |
74635367 |
AF180527 |
1796 |
2p13 |
Hs.103854 |
52 |
insulin receptor binding protein binding cell surface receptor linked signal transduction transmembrane receptor protein tyrosine kinase signaling pathway |
|
204856_at |
B3GNT3 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
19 |
17766918 |
NM_014256 |
10331 |
19p13.1 |
Hs.657825 Hs.69009 |
13 |
Golgi apparatus integral to plasma membrane protein amino acid glycosylation galactosyltransferase activity membrane transferase activity, transferring glycosyl groups |
Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
232316_at |
C14orf174 |
chromosome 14 open reading frame 174 |
14 |
76913514 |
AA972465 |
161394 |
14q24.3 |
Hs.421961 |
4 |
|
|
212573_at |
ENDOD1 |
endonuclease domain containing 1 |
11 |
94462664 |
AF131747 |
23052 |
11q21 |
Hs.167115 |
6 |
nucleic acid binding endonuclease activity extracellular region hydrolase activity metal ion binding |
Apoptosis |
202583_s_at |
RANBP9 |
RAN binding protein 9 |
6 |
-13729708 |
NM_005493 |
10048 |
6p23 |
Hs.708182 |
37 |
nucleus cytoplasm microtubule associated complex protein complex assembly microtubule nucleation Ran GTPase binding enzyme binding |
|
1558875_at |
SREBF1 |
sterol regulatory element binding transcription factor 1 |
17 |
-17656110 |
S66168 |
6720 |
17p11.2 |
Hs.592123 |
136 |
transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus nuclear envelope endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus regulation of transcription from RNA polymerase II promoter lipid metabolic process steroid metabolic process cholesterol metabolic process cellular response to starvation membrane integral to membrane cytoplasmic vesicle sterol response element binding regulation of transcription |
Insulin signaling pathway |
201397_at |
PHGDH |
phosphoglycerate dehydrogenase |
1 |
120055941 |
NM_006623 |
26227 |
1p12 |
Hs.487296 |
18 |
phosphoglycerate dehydrogenase activity L-serine biosynthetic process brain development cellular amino acid biosynthetic process electron carrier activity oxidoreductase activity cofactor binding NAD or NADH binding oxidation reduction |
Glycine, serine and threonine metabolism Metabolic pathways |
206348_s_at |
0.256 |
3.208 |
2.679 |
1.702e-02 |
0.469 |
-3.006 |
PDK3 |
pyruvate dehydrogenase kinase, isozyme 3 |
X |
24393264, 24393264 |
NM_005391 |
5165 |
Xp22.11 |
Hs.658190 |
17 |
two-component sensor activity nucleotide binding pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrial matrix carbohydrate metabolic process glucose metabolic process signal transduction transferase activity peptidyl-histidine phosphorylation |
|
209676_at |
0.479 |
3.430 |
3.119 |
6.944e-03 |
0.370 |
-2.246 |
TFPI |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
2 |
-188051550, -188037202 |
J03225 |
7035 |
2q32 |
Hs.516578 |
118 |
serine-type endopeptidase inhibitor activity extracellular region extracellular region extracellular space plasma membrane blood coagulation, extrinsic pathway |
Complement and coagulation cascades |
221471_at |
SERINC3 |
serine incorporator 3 |
20 |
-42561314, -42558277 |
AW173623 |
10955 |
20q13.1-q13.3 |
Hs.272168 Hs.696043 |
10 |
protein binding Golgi apparatus plasma membrane induction of apoptosis integral to membrane |
|
209556_at |
NCDN |
neurochondrin |
1 |
35795979 |
AB011179 |
23154 |
1p34.3 |
Hs.121870 |
8 |
cytoplasm dendrite cell projection bone resorption regulation of neuronal synaptic plasticity |
|
231801_at |
NFATC2 |
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
20 |
-49441172, -49441171 |
AL035682 |
4773 |
20q13.2-q13.3 |
Hs.713650 |
93 |
cytokine production transcription factor activity protein binding nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription activator activity sequence-specific DNA binding positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
MAPK signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway |
221580_s_at |
TAF1D |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
11 |
-93108745 |
BC001972 |
79101 |
11q21 |
Hs.355750 |
6 |
DNA binding protein binding nucleus regulation of transcription |
|
229971_at |
GPR114 |
G protein-coupled receptor 114 |
16 |
56134101 |
BF057784 |
221188 |
16q21 |
Hs.187884 |
7 |
G-protein coupled receptor activity G-protein coupled receptor activity plasma membrane neuropeptide signaling pathway integral to membrane integral to membrane |
|
211992_at |
WNK1 |
WNK lysine deficient protein kinase 1 |
12 |
732485 |
AI445745 |
65125 |
12p13.3 |
Hs.709894 |
51 |
nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process |
|
1552258_at |
NCRNA00152 |
non-protein coding RNA 152 |
2 |
87536088 |
NM_052871 |
112597 |
2p11.2 |
Hs.652166 |
2 |
|
|
1557063_at |
FLJ45244 |
hypothetical locus FLJ45244 |
14 |
94693777 |
BC040596 |
400242 |
14q32.13 |
Hs.497573 Hs.712518 |
1 |
|
|
217982_s_at |
MORF4L1 |
mortality factor 4 like 1 |
15 |
76952226 |
NM_006791 |
10933 |
15q24 |
Hs.374503 |
25 |
protein binding nucleus DNA repair response to DNA damage stimulus chromatin modification histone deacetylation Sin3 complex NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation regulation of transcription |
|
225729_at |
C6orf89 |
chromosome 6 open reading frame 89 |
6 |
36961617 |
AI870857 |
221477 |
6p21.2 |
Hs.433381 |
10 |
membrane integral to membrane |
|
214543_x_at |
QKI |
quaking homolog, KH domain RNA binding (mouse) |
6 |
163755664, 163755664 |
AF142421 |
9444 |
6q26 6q26-q27 |
Hs.510324 Hs.593520 |
23 |
RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport |
|
201388_at |
PSMD3 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
17 |
35390585 |
NM_002809 |
5709 |
17q21.1 |
Hs.12970 |
34 |
proteasome complex protein binding cytosol enzyme regulator activity anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
214690_at |
TAF1B |
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa |
2 |
9901021 |
AA004579 |
9014 |
2p25 |
Hs.584833 |
15 |
transcription factor activity nucleus nucleoplasm transcription, DNA-dependent regulation of transcription |
|
214108_at |
MAX |
MYC associated factor X |
14 |
-64620214, -64614273, -64611597, -64542644 |
AI346181 |
4149 |
14q23 |
Hs.285354 Hs.712926 |
56 |
transcription factor activity transcription coactivator activity protein binding nucleus cytoplasm transcription from RNA polymerase II promoter regulation of transcription |
MAPK signaling pathway Pathways in cancer Small cell lung cancer |
219381_at |
C5orf42 |
chromosome 5 open reading frame 42 |
5 |
-37142086 |
NM_023073 |
65250 |
5p13.2 |
Hs.170993 Hs.586199 Hs.643420 Hs.649870 Hs.649889 Hs.705282 |
4 |
membrane integral to membrane |
|
1563053_at |
0.293 |
2.099 |
2.453 |
2.671e-02 |
0.523 |
-3.385 |
LOC729083 |
hypothetical protein LOC729083 |
3 |
|
BC038366 |
729083 |
3p22.1 |
Hs.713395 |
|
|
|
229272_at |
FNBP4 |
formin binding protein 4 |
11 |
-47694644 |
AI083506 |
23360 |
11p11.2 |
Hs.6834 |
11 |
protein binding |
|
241725_at |
E2F7 |
E2F transcription factor 7 |
12 |
-75939156 |
AW511293 |
144455 |
12q21.2 |
Hs.416375 |
12 |
transcription factor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle negative regulation of cell proliferation transcription repressor activity identical protein binding |
|
220626_at |
SERPINA10 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
14 |
-93819402, -93819402 |
NM_016186 |
51156 |
14q32.13 |
Hs.118620 |
15 |
serine-type endopeptidase inhibitor activity extracellular region peptidase inhibitor activity |
|
1552436_a_at |
CDH23 |
cadherin-like 23 |
10 |
72826709, 72826709 |
NM_052836 |
64072 |
10q21-q22 |
Hs.656032 |
37 |
calcium ion binding protein binding plasma membrane cell adhesion homophilic cell adhesion sensory perception of sound integral to membrane calcium-dependent cell-cell adhesion stereocilium photoreceptor cell maintenance response to stimulus equilibrioception |
|
212488_at |
0.646 |
5.847 |
3.157 |
6.416e-03 |
0.364 |
-2.179 |
COL5A1 |
collagen, type V, alpha 1 |
9 |
136673472 |
N30339 |
1289 |
9q34.2-q34.3 |
Hs.210283 |
49 |
integrin binding extracellular matrix structural constituent extracellular region collagen collagen type V cell adhesion heparin binding collagen fibril organization collagen fibril organization collagen biosynthetic process wound healing, spreading of epidermal cells fibril organization proteoglycan binding skin development integrin biosynthetic process eye morphogenesis |
Focal adhesion ECM-receptor interaction |
209533_s_at |
PLAA |
phospholipase A2-activating protein |
9 |
-26893368 |
AF145020 |
9373 |
9p21 |
Hs.27182 |
15 |
protein binding phospholipid metabolic process inflammatory response signal transduction phospholipase A2 activator activity |
|
227481_at |
0.643 |
4.602 |
3.186 |
6.052e-03 |
0.360 |
-2.129 |
CNKSR3 |
CNKSR family member 3 |
6 |
-154768124 |
BG165333 |
154043 |
6q25.2 |
Hs.16064 |
2 |
protein binding cytoplasm regulation of signal transduction membrane |
|
1559645_at |
NCRNA00184 |
non-protein coding RNA 184 |
1 |
|
AJ421679 |
100302691 |
1q42.3 |
Hs.209162 |
|
|
|
235371_at |
0.738 |
4.976 |
2.818 |
1.284e-02 |
0.431 |
-2.768 |
GLT8D4 |
glycosyltransferase 8 domain containing 4 |
3 |
73020074 |
AI452595 |
727936 |
3p13 |
Hs.710275 |
1 |
membrane integral to membrane transferase activity, transferring glycosyl groups |
|
204303_s_at |
KIAA0427 |
KIAA0427 |
18 |
44319424 |
NM_014772 |
9811 |
18q21.1 |
Hs.145230 |
5 |
protein binding RNA metabolic process |
|
219081_at |
ANKHD1 |
ankyrin repeat and KH domain containing 1 |
5 |
139761612, 139761612 |
NM_024668 |
54882 |
5q31.3 |
Hs.594084 |
12 |
RNA binding protein binding cytoplasm |
|
1559920_a_at |
CECR4 |
cat eye syndrome chromosome region, candidate 4 (non-protein coding) |
22 |
16020278 |
AF307448 |
100130717 |
22q11.1 |
Hs.660066 |
1 |
|
|
223465_at |
COL4A3BP |
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
5 |
-74702683, -74702683 |
BE967275 |
10087 |
5q13.3 |
Hs.270437 |
26 |
protein kinase activity protein binding cellular_component cytoplasm endoplasmic reticulum Golgi apparatus protein amino acid phosphorylation lipid transport immune response |
|
202130_at |
RIOK3 |
RIO kinase 3 (yeast) |
18 |
19286784 |
AA725102 |
8780 |
18q11.2 |
Hs.445511 Hs.719109 |
9 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation chromosome segregation kinase activity transferase activity |
|
244565_at |
HMX2 |
H6 family homeobox 2 |
10 |
124897627 |
AI685824 |
3167 |
10q25.2-q26.3 |
Hs.444756 |
3 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development nervous system development brain development positive regulation of cell proliferation cell differentiation inner ear morphogenesis sequence-specific DNA binding |
|
224846_at |
SHKBP1 |
SH3KBP1 binding protein 1 |
19 |
45774596 |
AI348000 |
92799 |
19q13.2 |
Hs.26506 |
7 |
voltage-gated potassium channel activity protein binding potassium ion transport voltage-gated potassium channel complex membrane |
|
202585_s_at |
NFX1 |
nuclear transcription factor, X-box binding 1 |
9 |
33280509, 33280509, 33280509 |
NM_002504 |
4799 |
9p13.3 |
Hs.413074 |
15 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent inflammatory response zinc ion binding ligase activity modification-dependent protein catabolic process interspecies interaction between organisms negative regulation of MHC class II biosynthetic process metal ion binding |
|
209863_s_at |
TP63 |
tumor protein p63 |
3 |
190831909, 190831909, 190990142, 190990142 |
AF091627 |
8626 |
3q28 |
Hs.137569 |
238 |
response to tumor cell transcription factor activity nucleus nucleus cytoplasm apoptosis induction of apoptosis multicellular organismal development zinc ion binding transcription activator activity transcription activator activity transcription repressor activity negative regulation of cell growth identical protein binding positive regulation of Notch signaling pathway negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent metal ion binding protein homotetramerization |
|
201088_at |
KPNA2 |
karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
17 |
63462309, -1713110 |
NM_002266 |
3838 |
17q24.2 |
Hs.594238 |
125 |
regulation of DNA recombination M phase specific microtubule process G2 phase of mitotic cell cycle protein binding nucleus nuclear pore nucleoplasm cytoplasm DNA metabolic process NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
216082_at |
NEU3 |
sialidase 3 (membrane sialidase) |
11 |
74377597 |
AK022450 |
10825 |
11q13.5 |
Hs.191074 |
25 |
exo-alpha-sialidase activity plasma membrane integral to plasma membrane carbohydrate metabolic process ganglioside catabolic process metabolic process hydrolase activity, acting on glycosyl bonds |
Other glycan degradation Sphingolipid metabolism |
1562537_at |
-0.305 |
3.999 |
-2.229 |
4.129e-02 |
0.571 |
-3.746 |
FCER1A |
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
1 |
157526127 |
BC015185 |
2205 |
1q23 |
Hs.897 |
74 |
positive regulation of type I hypersensitivity serotonin secretion receptor activity plasma membrane integral to plasma membrane cell surface receptor linked signal transduction activation of JUN kinase activity external side of plasma membrane leukotriene biosynthetic process IgE receptor activity positive regulation of mast cell degranulation positive regulation of interleukin-3 biosynthetic process positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling |
Fc epsilon RI signaling pathway Asthma |
51176_at |
MED27 |
mediator complex subunit 27 |
9 |
-133725319 |
AA131335 |
9442 |
9q34.1-q34.3 |
Hs.374262 |
13 |
transcription coactivator activity protein binding nucleus cytoplasm regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter regulation of transcription |
|
220601_at |
C16orf70 |
chromosome 16 open reading frame 70 |
16 |
65701415 |
NM_025187 |
80262 |
16q22.1 |
Hs.513666 |
7 |
protein binding |
|
202832_at |
GCC2 |
GRIP and coiled-coil domain containing 2 |
2 |
108432008, 108432067 |
NM_014635 |
9648 |
2q12.3 |
Hs.436505 Hs.469630 |
19 |
cytoplasm Golgi apparatus membrane identical protein binding |
|
225424_at |
GPAM |
glycerol-3-phosphate acyltransferase, mitochondrial |
10 |
-113899611 |
AB046780 |
57678 |
10q25.2 |
Hs.42586 |
16 |
glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity mitochondrion mitochondrial outer membrane cytosol metabolic process acyltransferase activity phospholipid biosynthetic process membrane integral to membrane transferase activity triglyceride biosynthetic process |
Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways |
220252_x_at |
CXorf21 |
chromosome X open reading frame 21 |
X |
-30486861 |
NM_025159 |
80231 |
Xp21.2 |
Hs.665009 |
4 |
|
|
221185_s_at |
IQCG |
IQ motif containing G |
3 |
-199100344, -199100343 |
NM_025111 |
84223 |
3q29 |
Hs.591675 |
6 |
|
|
225179_at |
UBE2K |
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) |
4 |
39376058 |
AA161140 |
3093 |
4p14 |
Hs.50308 Hs.714332 |
20 |
nucleotide binding ubiquitin-protein ligase activity protein binding ATP binding cytoplasm ubiquitin-dependent protein catabolic process ligase activity ubiquitin protein ligase binding post-translational protein modification regulation of protein metabolic process |
Ubiquitin mediated proteolysis |
205240_at |
0.415 |
5.059 |
2.551 |
2.199e-02 |
0.499 |
-3.222 |
GPSM2 |
G-protein signaling modulator 2 (AGS3-like, C. elegans) |
1 |
109221125 |
NM_013296 |
29899 |
1p13.3 |
Hs.584901 |
11 |
GTPase activator activity nucleus nucleolus cytoplasm Golgi apparatus cell cortex signal transduction G-protein coupled receptor protein signaling pathway identical protein binding |
|
230258_at |
0.522 |
3.944 |
2.788 |
1.365e-02 |
0.440 |
-2.820 |
GLIS3 |
GLIS family zinc finger 3 |
9 |
-3814127, -3814127 |
AI277316 |
169792 |
9p24.2 |
Hs.162125 Hs.644570 |
8 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity intracellular zinc ion binding nuclear part regulation of transcription positive regulation of transcription from RNA polymerase II promoter metal ion binding |
|
1554556_a_at |
-0.281 |
5.296 |
-2.820 |
1.280e-02 |
0.431 |
-2.765 |
ATP11B |
ATPase, class VI, type 11B |
3 |
183993984 |
BC033880 |
23200 |
3q27 |
Hs.478429 |
8 |
nucleotide binding magnesium ion binding phospholipid-translocating ATPase activity ATP binding nuclear inner membrane ATP biosynthetic process ion transport metabolic process ion transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism phospholipid transport aminophospholipid transport membrane integral to membrane hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
|
228748_at |
CD59 |
CD59 molecule, complement regulatory protein |
11 |
-33681131, -33681131, -33681131 |
AI653117 |
966 |
11p13 |
Hs.278573 Hs.709466 Hs.710641 |
107 |
protein binding extracellular region membrane fraction plasma membrane cell surface receptor linked signal transduction blood coagulation anchored to membrane anchored to external side of plasma membrane |
Complement and coagulation cascades Hematopoietic cell lineage |
230351_at |
0.615 |
5.499 |
3.680 |
2.182e-03 |
0.276 |
-1.261 |
LOC283481 |
hypothetical protein LOC283481 |
13 |
|
AW070248 |
283481 |
13q33.1 |
Hs.646604 |
2 |
|
|
216180_s_at |
SYNJ2 |
synaptojanin 2 |
6 |
158322906 |
AK026758 |
8871 |
6q25.3 |
Hs.434494 |
18 |
RNA binding inositol or phosphatidylinositol phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity protein binding membrane dephosphorylation hydrolase activity |
Inositol phosphate metabolism Metabolic pathways Phosphatidylinositol signaling system |
336_at |
-0.380 |
5.580 |
-3.459 |
3.447e-03 |
0.308 |
-1.650 |
TBXA2R |
thromboxane A2 receptor |
19 |
-3545503 |
D38081 |
6915 |
19p13.3 |
Hs.442530 |
79 |
receptor activity G-protein coupled receptor activity thromboxane A2 receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway regulation of vasoconstriction second-messenger-mediated signaling positive regulation of smooth muscle contraction |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
207993_s_at |
0.592 |
4.787 |
4.163 |
8.097e-04 |
0.214 |
-0.422 |
CHP |
calcium binding protein P22 |
15 |
39310728 |
NM_007236 |
11261 |
15q13.3 |
Hs.406234 Hs.706184 |
21 |
calcium ion binding cytoplasm potassium ion transport small GTPase mediated signal transduction potassium channel regulator activity |
MAPK signaling pathway Calcium signaling pathway Apoptosis Wnt signaling pathway Axon guidance VEGF signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS) |
218421_at |
CERK |
ceramide kinase |
22 |
-45458970 |
NM_022766 |
64781 |
22q13.31 |
Hs.200668 |
21 |
nucleotide binding magnesium ion binding integral to membrane of membrane fraction ceramide kinase activity diacylglycerol kinase activity calcium ion binding ATP binding nucleus cytoplasm ceramide metabolic process activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway membrane transferase activity |
Sphingolipid metabolism |
243116_at |
PIP5KL1 |
phosphatidylinositol-4-phosphate 5-kinase-like 1 |
9 |
-129723630, -129723628 |
AI923090 |
138429 |
9q34.11 |
Hs.445486 |
2 |
nucleotide binding protein binding ATP binding cytoplasm membrane kinase activity 1-phosphatidylinositol-4-phosphate 5-kinase activity transferase activity cell projection phosphatidylinositol metabolic process |
|
1556411_s_at |
KY |
kyphoscoliosis peptidase |
3 |
-135801454 |
AF086360 |
339855 |
3q22.2 |
Hs.146730 |
4 |
cytoplasm cytoskeleton peptidase activity |
|
212187_x_at |
PTGDS |
prostaglandin D2 synthase 21kDa (brain) |
9 |
138991776 |
NM_000954 |
5730 |
9q34.2-q34.3 |
Hs.446429 |
63 |
prostaglandin biosynthetic process prostaglandin-D synthase activity transporter activity binding retinoid binding extracellular region nucleus cytoplasm rough endoplasmic reticulum Golgi apparatus fatty acid biosynthetic process transport membrane isomerase activity nuclear membrane regulation of circadian sleep/wake cycle, sleep perinuclear region of cytoplasm |
Arachidonic acid metabolism Metabolic pathways |
210830_s_at |
0.516 |
6.702 |
2.715 |
1.583e-02 |
0.459 |
-2.945 |
PON2 |
paraoxonase 2 |
7 |
-94872109 |
AF001602 |
5445 |
7q21.3 |
Hs.719159 |
112 |
aryldialkylphosphatase activity arylesterase activity extracellular region plasma membrane hydrolase activity aromatic compound catabolic process identical protein binding |
gamma-Hexachlorocyclohexane degradation Bisphenol A degradation Metabolic pathways |
220484_at |
MCOLN3 |
mucolipin 3 |
1 |
-85256352 |
NM_018298 |
55283 |
1p22.3 |
Hs.535239 |
11 |
ion channel activity ion transport membrane integral to membrane |
|
220929_at |
GALNT8 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8) |
12 |
4700012 |
NM_017417 |
26290 |
12p13.3 |
Hs.511985 |
2 |
polypeptide N-acetylgalactosaminyltransferase activity calcium ion binding sugar binding Golgi apparatus membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding |
O-Glycan biosynthesis Metabolic pathways |
216484_x_at |
HDGF |
hepatoma-derived growth factor (high-mobility group protein 1-like) |
1 |
-154978522, -154978522, -154978522 |
L24521 |
3068 |
1q21-q23 |
Hs.506748 |
22 |
nucleotide binding DNA binding extracellular space nucleus cytoplasm signal transduction growth factor activity heparin binding cell proliferation regulation of transcription |
|
214434_at |
HSPA12A |
heat shock 70kDa protein 12A |
10 |
-118420692 |
AB007877 |
259217 |
10q26.12 |
Hs.654682 |
8 |
nucleotide binding ATP binding |
|
205685_at |
CD86 |
CD86 molecule |
3 |
123256910, 123279439 |
BG236280 |
942 |
3q21 |
Hs.171182 |
97 |
protein binding plasma membrane immune response cell-cell signaling positive regulation of cell proliferation coreceptor activity integral to membrane transcription activator activity T cell activation positive regulation of lymphotoxin A biosynthetic process interspecies interaction between organisms positive regulation of interleukin-2 biosynthetic process positive regulation of interleukin-4 biosynthetic process positive regulation of T-helper 2 cell differentiation positive regulation of transcription |
Cell adhesion molecules (CAMs) Toll-like receptor signaling pathway Type I diabetes mellitus Autoimmune thyroid disease Systemic lupus erythematosus Allograft rejection Graft-versus-host disease |
36545_s_at |
SFI1 |
Sfi1 homolog, spindle assembly associated (yeast) |
22 |
30222260 |
AB011114 |
9814 |
22q12.2 |
Hs.62209 |
7 |
centrosome |
|
208447_s_at |
PRPS1 |
phosphoribosyl pyrophosphate synthetase 1 |
X |
106758309 |
NM_002764 |
5631 |
Xq21.32-q24 |
Hs.56 |
26 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding cytosol purine base metabolic process purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process kinase activity transferase activity urate biosynthetic process protein homodimerization activity hypoxanthine biosynthetic process |
Pentose phosphate pathway Purine metabolism Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways |
207137_at |
NFKBIL2 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 |
8 |
-145624970 |
NM_013432 |
4796 |
8q24.3 |
Hs.675285 |
6 |
transcription corepressor activity protein binding cytoplasm cytoplasmic sequestering of transcription factor |
|
205320_at |
APC2 |
adenomatosis polyposis coli 2 |
19 |
1401147 |
NM_005883 |
10297 |
19p13.3 |
Hs.446376 |
9 |
cytoplasm Golgi apparatus cytoskeleton microtubule plasma membrane protein complex assembly signal transduction beta-catenin binding microtubule binding Wnt receptor signaling pathway catenin complex |
Wnt signaling pathway Regulation of actin cytoskeleton Pathways in cancer Colorectal cancer Endometrial cancer Basal cell carcinoma |
209393_s_at |
EIF4E2 |
eukaryotic translation initiation factor 4E family member 2 |
2 |
233123600 |
AF047695 |
9470 |
2q37.1 |
Hs.292026 Hs.700929 |
15 |
RNA cap binding translation initiation factor activity protein binding cytoplasm translational initiation regulation of translation |
mTOR signaling pathway Insulin signaling pathway |
202235_at |
-0.592 |
7.042 |
-3.183 |
6.092e-03 |
0.360 |
-2.135 |
SLC16A1 |
solute carrier family 16, member 1 (monocarboxylic acid transporter 1) |
1 |
-113255992 |
BF511091 |
6566 |
1p12 |
Hs.75231 |
43 |
protein binding membrane fraction plasma membrane transport mevalonate transmembrane transporter activity symporter activity secondary active monocarboxylate transmembrane transporter activity organic anion transport mevalonate transport integral to membrane |
|
221522_at |
ANKRD27 |
ankyrin repeat domain 27 (VPS9 domain) |
19 |
-37779746 |
AL136784 |
84079 |
19q13.11 |
Hs.59236 |
12 |
guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm lysosome early endosome early endosome to late endosome transport |
|
1553678_a_at |
0.513 |
8.235 |
2.886 |
1.119e-02 |
0.426 |
-2.652 |
ITGB1 |
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
10 |
-33236244, -33229251, -33229251, -33229251 |
NM_133376 |
3688 |
10p11.2 |
Hs.643813 |
512 |
G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation |
Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
223605_at |
SLC25A18 |
solute carrier family 25 (mitochondrial carrier), member 18 |
22 |
16423182 |
AY008285 |
83733 |
22q11.2 |
Hs.282982 Hs.629929 |
7 |
binding mitochondrion mitochondrial inner membrane transport symporter activity membrane integral to membrane |
|
1558028_x_at |
LOC647979 |
hypothetical LOC647979 |
20 |
-34096955 |
BI857154 |
647979 |
20q11.23 |
Hs.649310 Hs.718413 |
2 |
|
|
230151_at |
C13orf1 |
chromosome 13 open reading frame 1 |
13 |
-49384842 |
AW009330 |
57213 |
13q14 |
Hs.44235 |
11 |
|
|
225055_at |
LOC651250 |
hypothetical LOC651250 |
17 |
63609332 |
AV735241 |
651250 |
17q24.2 |
Hs.293560 Hs.591212 Hs.647405 Hs.655146 Hs.663262 |
3 |
|
|
225019_at |
CAMK2D |
calcium/calmodulin-dependent protein kinase II delta |
4 |
-114597792, -114591638 |
BF797381 |
817 |
4q26 |
Hs.144114 |
29 |
G1/S transition of mitotic cell cycle nucleotide binding regulation of cell growth calmodulin-dependent protein kinase activity calmodulin binding ATP binding nucleus cytoplasm calcium- and calmodulin-dependent protein kinase complex calcium ion transport transferase activity T-tubule protein amino acid autophosphorylation cardiac muscle contraction |
ErbB signaling pathway Calcium signaling pathway Wnt signaling pathway Long-term potentiation Neurotrophin signaling pathway Olfactory transduction GnRH signaling pathway Melanogenesis Glioma |
209440_at |
PRPS1 |
phosphoribosyl pyrophosphate synthetase 1 |
X |
106758309 |
BC001605 |
5631 |
Xq21.32-q24 |
Hs.56 |
26 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding cytosol purine base metabolic process purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process kinase activity transferase activity urate biosynthetic process protein homodimerization activity hypoxanthine biosynthetic process |
Pentose phosphate pathway Purine metabolism Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways |
224436_s_at |
0.616 |
7.121 |
2.291 |
3.661e-02 |
0.560 |
-3.647 |
NIPSNAP3A |
nipsnap homolog 3A (C. elegans) |
9 |
106549789 |
BC005935 |
25934 |
9q31.1 |
Hs.530275 |
6 |
cytoplasm cytosol |
|
212698_s_at |
SEPT10 |
septin 10 |
2 |
-109657664 |
BF966021 |
151011 |
2q13 |
Hs.469615 |
6 |
nucleotide binding protein binding GTP binding nucleus cytoplasm cell cycle septin complex cell division |
|
1570279_at |
ABCA1 |
ATP-binding cassette, sub-family A (ABC1), member 1 |
9 |
-106583104 |
BC034824 |
19 |
9q31.1 |
Hs.719214 |
321 |
nucleotide binding ATP binding phospholipid binding phospholipid transporter activity membrane fraction integral to plasma membrane lipid metabolic process transport lysosome organization G-protein coupled receptor protein signaling pathway steroid metabolic process cholesterol metabolic process anion transmembrane transporter activity negative regulation of foam cell differentiation negative regulation of cholesterol storage cholesterol binding membrane endosome transport ATPase activity cholesterol transporter activity syntaxin-13 binding positive regulation of cAMP biosynthetic process small GTPase binding intracellular cholesterol transport Cdc42 protein signal transduction cholesterol efflux cholesterol efflux phospholipid efflux phospholipid efflux apolipoprotein A-I receptor activity high-density lipoprotein particle assembly cholesterol homeostasis reverse cholesterol transport membrane raft phagocytic vesicle interleukin-1 beta secretion phospholipid homeostasis platelet dense granule organization |
ABC transporters |
205356_at |
USP13 |
ubiquitin specific peptidase 13 (isopeptidase T-3) |
3 |
180853626 |
NM_003940 |
8975 |
3q26.2-q26.3 |
Hs.175322 |
11 |
cysteine-type endopeptidase activity ubiquitin thiolesterase activity ubiquitin-specific protease activity ubiquitin-dependent protein catabolic process peptidase activity zinc ion binding metal ion binding |
|
209220_at |
GPC3 |
glypican 3 |
X |
-132497441 |
L47125 |
2719 |
Xq26.1 |
Hs.644108 |
53 |
extracellular region proteinaceous extracellular matrix extracellular space plasma membrane integral to plasma membrane anatomical structure morphogenesis anchored to membrane heparan sulfate proteoglycan binding |
|
1564783_x_at |
-0.237 |
4.534 |
-2.181 |
4.530e-02 |
0.581 |
-3.823 |
OFCC1 |
orofacial cleft 1 candidate 1 |
6 |
|
AF520806 |
266553 |
6p24.3 |
Hs.532138 |
2 |
|
|
224559_at |
0.607 |
7.327 |
2.868 |
1.161e-02 |
0.426 |
-2.682 |
MALAT1 |
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) |
11 |
65021808 |
AF001540 |
378938 |
11q13.1 |
Hs.642877 Hs.714394 |
8 |
|
|
212898_at |
KIAA0406 |
KIAA0406 |
20 |
-36044836 |
AB007866 |
9675 |
20q11.23 |
Hs.655481 |
5 |
binding |
|
1559489_a_at |
-0.215 |
4.708 |
-2.279 |
3.749e-02 |
0.563 |
-3.667 |
LOC257358 |
hypothetical LOC257358 |
5 |
169691012 |
AK093725 |
257358 |
5q35.1 |
Hs.249689 |
3 |
|
|
219970_at |
GIPC2 |
GIPC PDZ domain containing family, member 2 |
1 |
78284176 |
NM_017655 |
54810 |
1p31.1 |
Hs.659356 |
9 |
protein binding cytoplasm |
|
203589_s_at |
0.458 |
5.744 |
2.375 |
3.112e-02 |
0.543 |
-3.512 |
TFDP2 |
transcription factor Dp-2 (E2F dimerization partner 2) |
3 |
-143154017 |
NM_006286 |
7029 |
3q23 |
Hs.379018 |
14 |
transcription factor activity transcription cofactor activity nucleus transcription factor complex regulation of transcription, DNA-dependent cell cycle protein domain specific binding |
Cell cycle |
211994_at |
WNK1 |
WNK lysine deficient protein kinase 1 |
12 |
732485 |
AI742553 |
65125 |
12p13.3 |
Hs.709894 |
51 |
nucleotide binding molecular_function protein serine/threonine kinase activity protein kinase inhibitor activity protein binding ATP binding cytoplasm cytoplasm protein amino acid phosphorylation ion transport protein kinase cascade biological_process transferase activity regulation of cellular process |
|
204411_at |
KIF21B |
kinesin family member 21B |
1 |
-199205142 |
NM_017596 |
23046 |
1pter-q31.3 |
Hs.169182 |
3 |
nucleotide binding microtubule motor activity ATP binding cytoplasm microtubule microtubule-based movement |
|
220495_s_at |
TXNDC15 |
thioredoxin domain containing 15 |
5 |
134237358 |
NM_024715 |
79770 |
5q31.1 |
Hs.696335 |
7 |
membrane integral to membrane cell redox homeostasis |
|
202416_at |
DNAJC7 |
DnaJ (Hsp40) homolog, subfamily C, member 7 |
17 |
-37381982, -37381982 |
NM_003315 |
7266 |
17q11.2 |
Hs.500156 |
13 |
protein folding heat shock protein binding |
|
207320_x_at |
STAU1 |
staufen, RNA binding protein, homolog 1 (Drosophila) |
20 |
-47163282 |
NM_004602 |
6780 |
20q13.1 |
Hs.596704 |
26 |
double-stranded RNA binding protein binding intracellular rough endoplasmic reticulum microtubule associated complex intracellular mRNA localization ribonucleoprotein complex |
|
211851_x_at |
-0.324 |
5.731 |
-3.235 |
5.469e-03 |
0.352 |
-2.043 |
BRCA1 |
breast cancer 1, early onset |
17 |
-38449838, -38449838, -38449838, -38449838 |
AF005068 |
672 |
17q21 |
Hs.194143 |
1201 |
ubiquitin ligase complex double-strand break repair via homologous recombination condensed chromosome damaged DNA binding transcription coactivator activity ubiquitin-protein ligase activity intracellular nucleus nucleoplasm cytoplasm DNA replication postreplication repair regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase III promoter response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle chromosome segregation centrosome cycle zinc ion binding gamma-tubulin ring complex DNA damage response, signal transduction resulting in induction of apoptosis dosage compensation, by inactivation of X chromosome response to ionizing radiation tubulin binding negative regulation of transcription ligase activity enzyme binding modification-dependent protein catabolic process androgen receptor signaling pathway ribonucleoprotein complex positive regulation of protein ubiquitination BRCA1-BARD1 complex G2/M transition DNA damage checkpoint regulation of cell proliferation identical protein binding regulation of apoptosis chordate embryonic development response to estrogen stimulus negative regulation of fatty acid biosynthetic process positive regulation of DNA repair positive regulation of transcription, DNA-dependent negative regulation of centriole replication metal ion binding androgen receptor binding BRCA1-A complex |
Ubiquitin mediated proteolysis |
202093_s_at |
PAF1 |
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) |
19 |
-44568109 |
NM_019088 |
54623 |
19q13.1 |
Hs.466714 |
5 |
nucleus histone monoubiquitination Cdc73/Paf1 complex histone H2B ubiquitination regulation of transcription |
|
203849_s_at |
-0.330 |
4.367 |
-3.244 |
5.365e-03 |
0.351 |
-2.027 |
KIF1A |
kinesin family member 1A |
2 |
-241301856 |
BG473130 |
547 |
2q37.3 |
Hs.516802 |
21 |
nucleotide binding microtubule motor activity ATP binding microtubule microtubule-based movement anterograde axon cargo transport |
|
211762_s_at |
KPNA2 |
karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
17 |
63462309, -1713110 |
BC005978 |
3838 |
17q24.2 |
Hs.594238 |
125 |
regulation of DNA recombination M phase specific microtubule process G2 phase of mitotic cell cycle protein binding nucleus nuclear pore nucleoplasm cytoplasm DNA metabolic process NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
205290_s_at |
BMP2 |
bone morphogenetic protein 2 |
20 |
6696744 |
NM_001200 |
650 |
20p12 |
Hs.73853 |
195 |
branching involved in ureteric bud morphogenesis cytokine activity extracellular region extracellular region extracellular space inflammatory response cell-cell signaling growth factor activity negative regulation of cell proliferation embryonic development organ morphogenesis positive regulation of pathway-restricted SMAD protein phosphorylation specific transcriptional repressor activity positive regulation of bone mineralization BMP signaling pathway BMP signaling pathway negative regulation of gene-specific transcription cardiac cell differentiation growth odontogenesis of dentine-containing tooth cell fate commitment positive regulation of osteoblast differentiation negative regulation of cell cycle positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter SMAD binding positive regulation of astrocyte differentiation cartilage development cardiac epithelial to mesenchymal transition |
Cytokine-cytokine receptor interaction Hedgehog signaling pathway TGF-beta signaling pathway Pathways in cancer Basal cell carcinoma |
214670_at |
0.445 |
5.726 |
2.403 |
2.942e-02 |
0.536 |
-3.465 |
ZKSCAN1 |
zinc finger with KRAB and SCAN domains 1 |
7 |
99451154 |
AA653300 |
7586 |
7q21.3-q22.1 |
Hs.615360 |
11 |
transcription factor activity intracellular nucleus cytoplasm mitochondrion regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
213036_x_at |
-0.260 |
6.100 |
-2.614 |
1.937e-02 |
0.489 |
-3.115 |
ATP2A3 |
ATPase, Ca++ transporting, ubiquitous |
17 |
-3773917 |
Y15724 |
489 |
17p13.3 |
Hs.513870 |
27 |
nucleotide binding magnesium ion binding calcium-transporting ATPase activity calcium ion binding protein binding ATP binding nucleus ATP biosynthetic process cation transport calcium ion transport metabolic process membrane integral to membrane sarcoplasmic reticulum hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
Calcium signaling pathway Alzheimer's disease |
229018_at |
C12orf26 |
chromosome 12 open reading frame 26 |
12 |
81276454 |
AI310001 |
84190 |
12q21.31 |
Hs.506222 |
3 |
|
|
210940_s_at |
GRM1 |
glutamate receptor, metabotropic 1 |
6 |
146390474 |
U31216 |
2911 |
6q24 |
Hs.32945 |
51 |
receptor activity G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway synaptic transmission glutamate receptor activity |
Calcium signaling pathway Neuroactive ligand-receptor interaction Gap junction Long-term potentiation Long-term depression |
216525_x_at |
PMS2L3 |
postmeiotic segregation increased 2-like 3 |
7 |
-74975005, -74975004 |
D38437 |
5387 |
7q11.23 |
Hs.406395 Hs.659871 Hs.661055 |
4 |
molecular_function nucleic acid binding ATP binding cellular_component intracellular regulation of transcription, DNA-dependent biological_process |
|
229849_at |
WIPF3 |
WAS/WASL interacting protein family, member 3 |
7 |
29840865 |
AI807950 |
644150 |
7p14.3 |
Hs.709280 |
5 |
actin binding cytoplasm multicellular organismal development spermatogenesis cell differentiation |
|
231930_at |
ELMOD1 |
ELMO/CED-12 domain containing 1 |
11 |
106967026 |
AL359601 |
55531 |
11q22.3 |
Hs.495779 |
5 |
cytoskeleton phagocytosis |
|
201750_s_at |
ECE1 |
endothelin converting enzyme 1 |
1 |
-21416326, -21416326, -21416326, -21416326 |
NM_001397 |
1889 |
1p36.1 |
Hs.195080 |
63 |
response to hypoxia positive regulation of receptor recycling regulation of systemic arterial blood pressure by endothelin metalloendopeptidase activity membrane fraction endosome Golgi apparatus plasma membrane proteolysis apoptosis heart development peptidase activity zinc ion binding external side of plasma membrane substance P catabolic process bradykinin catabolic process calcitonin catabolic process integral to membrane peptide hormone binding regulation of vasoconstriction intrinsic to endosome membrane vesicle Weibel-Palade body endothelin maturation embryonic digit morphogenesis protein homodimerization activity ear development positive regulation of G-protein coupled receptor protein signaling pathway metal ion binding perinuclear region of cytoplasm |
|
204573_at |
CROT |
carnitine O-octanoyltransferase |
7 |
86812886, 86812886 |
NM_021151 |
54677 |
7q21.1 |
Hs.125039 |
11 |
peroxisome generation of precursor metabolites and energy lipid metabolic process fatty acid metabolic process transport acyltransferase activity carnitine O-octanoyltransferase activity fatty acid transport transferase activity |
|
210395_x_at |
MYL4 |
myosin, light chain 4, alkali; atrial, embryonic |
17 |
42641426, 42641712 |
AF116676 |
4635 |
17q21-qter |
Hs.463300 |
21 |
regulation of the force of heart contraction motor activity actin monomer binding calcium ion binding muscle myosin complex muscle organ development structural constituent of muscle myosin complex A band myosin II heavy chain binding positive regulation of ATPase activity actin filament binding cardiac muscle contraction |
Cardiac muscle contraction |
1569895_at |
-0.282 |
6.971 |
-2.635 |
1.858e-02 |
0.486 |
-3.080 |
LOC100133612 |
similar to hCG1815312 |
1 |
3806827 |
BC016994 |
100133612 |
1p36.32 |
Hs.307652 |
1 |
|
|
238925_at |
SNTB2 |
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
16 |
67778550 |
AW958415 |
6645 |
16q22-q23 |
Hs.461117 |
22 |
actin binding calcium ion binding calmodulin binding membrane fraction cytoplasm cytoskeleton microtubule dystrophin-associated glycoprotein complex membrane cell junction cytoplasmic vesicle synapse |
|
241496_at |
BTNL9 |
butyrophilin-like 9 |
5 |
180399830 |
BE551319 |
153579 |
5q35.3 |
Hs.546502 |
4 |
membrane integral to membrane |
|
212885_at |
0.440 |
7.356 |
2.510 |
2.382e-02 |
0.509 |
-3.289 |
MPHOSPH10 |
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
2 |
71210951 |
AL545921 |
10199 |
2p13.3 |
Hs.656208 |
10 |
protein binding nucleus nucleolus small nucleolar ribonucleoprotein complex rRNA processing RNA splicing RNA splicing factor activity, transesterification mechanism |
|
224501_at |
C1orf170 |
chromosome 1 open reading frame 170 |
1 |
-900441 |
BC006300 |
84808 |
1p36.33 |
Hs.271462 |
2 |
|
|
229801_at |
C10orf47 |
chromosome 10 open reading frame 47 |
10 |
11905402 |
AI640157 |
254427 |
10p14 |
Hs.435775 |
4 |
|
|
230704_s_at |
ITGB4 |
integrin, beta 4 |
17 |
71229110, 71232370 |
AI418058 |
3691 |
17q25 |
Hs.632226 |
120 |
receptor activity protein binding cell communication cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex membrane integral to membrane |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
218330_s_at |
NAV2 |
neuron navigator 2 |
11 |
19328846, 19691456, 20001211 |
NM_018162 |
89797 |
11p15.1 |
Hs.502116 Hs.551898 Hs.639427 Hs.639428 |
18 |
nucleotide binding helicase activity ATP binding nucleus nucleolus cytoplasm hydrolase activity |
|
232938_at |
-0.216 |
4.389 |
-2.410 |
2.905e-02 |
0.534 |
-3.455 |
SFMBT2 |
Scm-like with four mbt domains 2 |
10 |
-7244254 |
AL118884 |
57713 |
10p14 |
Hs.407983 |
3 |
nucleus regulation of transcription |
|
211575_s_at |
UBE3A |
ubiquitin protein ligase E3A |
15 |
-23133488, -23133488, -23133488 |
AF116702 |
7337 |
15q11-q13 |
Hs.598862 |
76 |
ubiquitin-protein ligase activity protein binding intracellular nucleus cytosol protein modification process proteolysis ubiquitin-dependent protein catabolic process brain development protein ubiquitination ligase activity acid-amino acid ligase activity protein complex interspecies interaction between organisms |
Ubiquitin mediated proteolysis |
244250_at |
ANXA6 |
annexin A6 |
5 |
-150460460 |
AI917653 |
309 |
5q32-q34 |
Hs.412117 |
40 |
calcium ion binding protein binding calcium-dependent phospholipid binding cytoplasm melanosome |
|
221749_at |
YTHDF3 |
YTH domain family, member 3 |
8 |
64243674 |
AU157915 |
253943 |
8q12.3 |
Hs.491861 |
9 |
cytoplasm |
|
218983_at |
0.801 |
4.906 |
3.591 |
2.620e-03 |
0.287 |
-1.417 |
C1RL |
complement component 1, r subcomponent-like |
12 |
-7138290 |
NM_016546 |
51279 |
12p13.31 |
Hs.631730 |
8 |
serine-type endopeptidase activity extracellular region extracellular space proteolysis complement activation, classical pathway peptidase activity innate immune response |
|
220185_at |
SPTBN4 |
spectrin, beta, non-erythrocytic 4 |
19 |
45664965, 45728234 |
NM_025213 |
57731 |
19q13.13 |
Hs.32706 |
11 |
actin binding structural constituent of cytoskeleton protein binding cytoplasm cytoskeleton cell cortex cytoskeletal anchoring at plasma membrane axonogenesis sensory perception of sound adult walking behavior spectrin fertilization vesicle-mediated transport nuclear matrix PML body transmission of nerve impulse axon ankyrin binding adult behavior positive regulation of multicellular organism growth axon hillock actin filament capping |
|
228437_at |
CNIH4 |
cornichon homolog 4 (Drosophila) |
1 |
222611217 |
AA834560 |
29097 |
1q42.11 |
Hs.195403 Hs.445890 |
11 |
protein binding endoplasmic reticulum intracellular signaling cascade membrane integral to membrane |
|
1554385_a_at |
0.305 |
4.861 |
2.166 |
4.663e-02 |
0.582 |
-3.847 |
PADI2 |
peptidyl arginine deiminase, type II |
1 |
-17265842 |
BC009701 |
11240 |
1p36.13 |
Hs.33455 |
20 |
protein-arginine deiminase activity calcium ion binding cytoplasm protein modification process hydrolase activity peptidyl-citrulline biosynthetic process from peptidyl-arginine |
|
235675_at |
0.242 |
2.553 |
2.181 |
4.525e-02 |
0.581 |
-3.822 |
DHFRL1 |
dihydrofolate reductase-like 1 |
3 |
-95259455 |
AW104373 |
200895 |
3q11.1 |
Hs.718516 |
4 |
dihydrofolate reductase activity glycine biosynthetic process nucleotide biosynthetic process NADP or NADPH binding |
|
203394_s_at |
HES1 |
hairy and enhancer of split 1, (Drosophila) |
3 |
195336627 |
BE973687 |
3280 |
3q28-q29 |
Hs.250666 |
44 |
in utero embryonic development liver development DNA binding nucleus cytoplasm regulation of transcription, DNA-dependent cell adhesion positive regulation of cell proliferation positive regulation of specific transcription from RNA polymerase II promoter negative regulation of specific transcription from RNA polymerase II promoter transcription repressor activity midbrain-hindbrain boundary morphogenesis oculomotor nerve development trochlear nerve development hindbrain morphogenesis neural tube development pituitary gland development lung development midbrain development auditory receptor cell fate determination cell fate commitment negative regulation of auditory receptor cell differentiation negative regulation of neuron differentiation cell maturation cell morphogenesis involved in neuron differentiation regulation of neurogenesis regulation of timing of neuron differentiation |
Notch signaling pathway Maturity onset diabetes of the young |
241450_at |
RSPO1 |
R-spondin homolog (Xenopus laevis) |
1 |
-37849537 |
AI224952 |
284654 |
1p34.3 |
Hs.135015 |
13 |
extracellular region heparin binding Wnt receptor signaling pathway response to stimulus |
|
215859_at |
NCLN |
nicalin homolog (zebrafish) |
19 |
3136874 |
AK022309 |
56926 |
19p13.3 |
Hs.657032 |
11 |
protein binding nucleus nucleolus endoplasmic reticulum membrane integral to membrane protein processing |
|
209800_at |
KRT16 |
keratin 16 |
17 |
-37019556 |
AF061812 |
3868 |
17q12-q21 |
Hs.655160 |
29 |
structural constituent of cytoskeleton protein binding intermediate filament cell proliferation epidermis development intermediate filament cytoskeleton organization |
|
235402_at |
C11orf66 |
chromosome 11 open reading frame 66 |
11 |
61005167 |
AI866146 |
220004 |
11q12.2 |
Hs.502726 |
3 |
|
|
200906_s_at |
PALLD |
palladin, cytoskeletal associated protein |
4 |
169654791 |
AK025843 |
23022 |
4q32.3 |
Hs.151220 |
40 |
actin binding protein binding nucleus cytoplasm cytoskeleton actin filament cytoskeleton organization muscle alpha-actinin binding |
|
231397_at |
PAP2D |
phosphatidic acid phosphatase type 2 |
1 |
-99128388 |
AF131783 |
163404 |
1p21.3 |
Hs.483948 |
4 |
membrane integral to membrane hydrolase activity |
|
217561_at |
0.334 |
3.046 |
2.230 |
4.125e-02 |
0.571 |
-3.746 |
CALCA |
calcitonin-related polypeptide alpha |
11 |
-14946623, -14944791 |
BF447272 |
796 |
11p15.2-p15.1 |
Hs.37058 |
137 |
endothelial cell proliferation vasculature development neurological system process involved in regulation of systemic arterial blood pressure vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure regulation of heart rate hormone activity extracellular region extracellular space intracellular nucleus cytoplasm leukocyte adhesion activation of adenylate cyclase activity by G-protein signaling pathway neuropeptide signaling pathway cell-cell signaling embryo implantation feeding behavior response to heat negative regulation of calcium ion transport into cytosol negative regulation of transcription negative regulation of ossification axon negative regulation of neurological system process calcitonin receptor binding calcitonin receptor binding activation of protein kinase activity positive regulation of interleukin-1 alpha production positive regulation of interleukin-8 production cell soma terminal button endothelial cell migration positive regulation of macrophage differentiation negative regulation of osteoclast differentiation positive regulation of adenylate cyclase activity negative regulation of blood pressure positive regulation of ossification negative regulation of bone resorption positive regulation of cell adhesion positive regulation of vasodilation negative regulation of smooth muscle contraction response to pain regulation of inflammatory response detection of temperature stimulus involved in sensory perception of pain cytosolic calcium ion homeostasis elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
|
232249_at |
FMNL3 |
formin-like 3 |
12 |
-48317990 |
AL162062 |
91010 |
12q13.12 |
Hs.179838 |
6 |
actin binding protein binding cellular component organization Rho GTPase binding actin cytoskeleton organization |
|
212268_at |
0.509 |
6.390 |
2.715 |
1.582e-02 |
0.459 |
-2.945 |
SERPINB1 |
serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
6 |
-2778732 |
NM_030666 |
1992 |
6p25 |
Hs.381167 |
18 |
serine-type endopeptidase inhibitor activity cytoplasm peptidase inhibitor activity |
|
221730_at |
0.884 |
5.878 |
3.767 |
1.824e-03 |
0.270 |
-1.109 |
COL5A2 |
collagen, type V, alpha 2 |
2 |
-189604885 |
NM_000393 |
1290 |
2q14-q32 |
Hs.445827 |
29 |
molecular_function extracellular matrix structural constituent extracellular region collagen collagen type V collagen fibril organization collagen fibril organization skin development skin development eye morphogenesis |
Focal adhesion ECM-receptor interaction |
205567_at |
CHST1 |
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
11 |
-45627002 |
NM_003654 |
8534 |
11p11.2-p11.1 |
Hs.104576 |
18 |
Golgi membrane Golgi apparatus polysaccharide metabolic process galactose metabolic process inflammatory response membrane integral to membrane transferase activity keratan sulfate metabolic process keratan sulfotransferase activity |
Keratan sulfate biosynthesis Metabolic pathways |
227141_at |
0.408 |
6.809 |
2.913 |
1.058e-02 |
0.418 |
-2.604 |
TYW3 |
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) |
1 |
74971423, 74971427, 74971449 |
AW205739 |
127253 |
1p31.1 |
Hs.348411 |
6 |
tRNA processing methyltransferase activity transferase activity |
|
243526_at |
-0.394 |
4.336 |
-3.207 |
5.798e-03 |
0.357 |
-2.093 |
WDR86 |
WD repeat domain 86 |
7 |
-150709139 |
AI968904 |
349136 |
7q36.1 |
Hs.647083 |
2 |
|
|
234376_at |
-0.234 |
4.981 |
-2.135 |
4.942e-02 |
0.590 |
-3.894 |
MYCN |
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) |
2 |
15998133 |
M55330 |
4613 |
2p24.1 |
Hs.25960 |
115 |
chromatin transcription factor activity protein binding nucleus regulation of transcription from RNA polymerase II promoter |
|
230637_at |
-0.424 |
7.174 |
-2.874 |
1.147e-02 |
0.426 |
-2.672 |
SFXN4 |
sideroflexin 4 |
10 |
-120890414 |
BF109381 |
119559 |
10q26.11 |
Hs.655168 |
6 |
iron ion binding mitochondrion cation transport iron ion transport cation transmembrane transporter activity membrane integral to membrane |
|
223975_at |
SPRYD5 |
SPRY domain containing 5 |
11 |
55407348 |
BC005014 |
84767 |
11q11 |
Hs.326734 |
2 |
|
|
223938_at |
-0.232 |
5.726 |
-2.515 |
2.361e-02 |
0.508 |
-3.282 |
C1orf49 |
chromosome 1 open reading frame 49 |
1 |
176748834 |
AL136694 |
84066 |
1q25.2 |
Hs.534501 |
10 |
microtubule cytoskeleton |
|
214198_s_at |
DGCR2 |
DiGeorge syndrome critical region gene 2 |
22 |
-17403794 |
AU150824 |
9993 |
22q11.21 |
Hs.517357 |
14 |
receptor activity protein binding sugar binding microsome cell adhesion organ morphogenesis membrane integral to membrane response to drug |
|
208682_s_at |
MAGED2 |
melanoma antigen family D, 2 |
X |
54850895, 54851521, 54852217 |
AF126181 |
10916 |
Xp11.2 |
Hs.522665 |
13 |
|
|
224882_at |
0.509 |
6.600 |
2.900 |
1.086e-02 |
0.422 |
-2.626 |
ACSS1 |
acyl-CoA synthetase short-chain family member 1 |
20 |
-24934872 |
AL035661 |
84532 |
20p11.23-p11.21 |
Hs.529353 |
7 |
nucleotide binding acetate-CoA ligase activity ATP binding mitochondrion mitochondrial matrix metabolic process AMP binding ligase activity |
Glycolysis / Gluconeogenesis Pyruvate metabolism Propanoate metabolism Reductive carboxylate cycle (CO2 fixation) Metabolic pathways |
214335_at |
RPL18 |
ribosomal protein L18 |
19 |
-53810399 |
AI669349 |
6141 |
19q13 |
Hs.515517 |
16 |
RNA binding structural constituent of ribosome intracellular cytoplasm cytosol ribosome translational elongation cytosolic large ribosomal subunit |
Ribosome |
225566_at |
NRP2 |
neuropilin 2 |
2 |
206255468, 206255468, 206255468 |
AI819729 |
8828 |
2q33.3 |
Hs.471200 |
44 |
receptor activity vascular endothelial growth factor receptor activity membrane fraction plasma membrane cell adhesion multicellular organismal development nervous system development axon guidance integral to membrane cell differentiation |
|
1560573_at |
LOC387895 |
hypothetical gene supported by BC040060 |
12 |
|
BC040060 |
387895 |
12q24.32 |
Hs.534660 |
1 |
|
|
1555833_a_at |
IRGQ |
immunity-related GTPase family, Q |
19 |
-48780358 |
AK096168 |
126298 |
19q13.31 |
Hs.6217 |
5 |
protein binding |
|
206770_s_at |
SLC35A3 |
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
1 |
100208127 |
NM_012243 |
23443 |
1p21 |
Hs.448979 |
8 |
Golgi membrane nucleotide-sugar transmembrane transporter activity sugar:hydrogen symporter activity UDP-N-acetylglucosamine transmembrane transporter activity Golgi apparatus UDP-N-acetylglucosamine metabolic process nucleotide-sugar transport UDP-N-acetylglucosamine transport membrane integral to membrane |
|
241525_at |
LOC200772 |
hypothetical protein LOC200772 |
2 |
|
AV700191 |
200772 |
2q37.3 |
Hs.647893 |
|
|
|
212372_at |
0.903 |
7.144 |
2.992 |
9.015e-03 |
0.396 |
-2.468 |
MYH10 |
myosin, heavy chain 10, non-muscle |
17 |
-8318254 |
AK026977 |
4628 |
17p13 |
Hs.16355 |
37 |
microfilament motor activity nucleotide binding cytokinesis after mitosis in utero embryonic development stress fiber neuron migration plasma membrane repair calmodulin binding ATP binding cytoplasm spindle plasma membrane cell cortex exocytosis substrate-bound cell migration, cell extension nuclear migration axon guidance brain development adult heart development biological_process cell proliferation regulation of cell shape myosin complex fourth ventricle development lateral ventricle development third ventricle development cerebellar Purkinje cell layer development actin cytoskeleton organization actin filament-based movement axon growth cone midbody actin-dependent ATPase activity neuron projection development neuromuscular junction cleavage furrow cell soma dendritic spine ADP binding neuromuscular process controlling balance actin filament binding cardiac myofibril assembly ventricular cardiac muscle cell development retina development in camera-type eye |
Tight junction Regulation of actin cytoskeleton |
208835_s_at |
0.413 |
9.471 |
2.384 |
3.055e-02 |
0.541 |
-3.497 |
LUC7L3 |
LUC7-like 3 (S. cerevisiae) |
17 |
46151975 |
AW089673 |
51747 |
17q21.33 |
Hs.130293 |
15 |
DNA binding mRNA binding protein binding nucleus mRNA processing apoptosis response to stress RNA splicing nuclear speck |
|
1563863_x_at |
-0.248 |
4.451 |
-2.140 |
4.899e-02 |
0.590 |
-3.887 |
TCEANC |
transcription elongation factor A (SII) N-terminal and central domain containing |
X |
13581227 |
AK097032 |
170082 |
Xp22.2 |
Hs.222855 |
5 |
DNA binding transcription elongation regulator activity protein binding nucleus transcription regulation of transcription from RNA polymerase II promoter |
|
200812_at |
CCT7 |
chaperonin containing TCP1, subunit 7 (eta) |
2 |
73314912 |
NM_006429 |
10574 |
2p13.2 |
Hs.368149 |
18 |
nucleotide binding ATP binding cytoplasm protein folding unfolded protein binding |
|
227634_at |
STK32C |
serine/threonine kinase 32C |
10 |
-133870985 |
AW245946 |
282974 |
10q26.3 |
Hs.469002 |
4 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity |
|
1565325_at |
SNHG4 |
small nucleolar RNA host gene 4 (non-protein coding) |
5 |
138637676 |
AJ224170 |
724102 |
5q31.2 |
Hs.268939 |
5 |
|
|
223911_at |
LOC440330 |
hypothetical protein LOC440330 |
16 |
|
BC004968 |
440330 |
16p13.3 |
Hs.121180 |
1 |
|
|
206868_at |
STARD8 |
StAR-related lipid transfer (START) domain containing 8 |
X |
67784235, 67830217 |
NM_014725 |
9754 |
Xq13.1 |
Hs.95140 |
8 |
GTPase activator activity intracellular focal adhesion signal transduction cell junction |
|
236257_at |
CD2AP |
CD2-associated protein |
6 |
47553483 |
AI244614 |
23607 |
6p12 |
Hs.485518 |
37 |
ruffle structural constituent of cytoskeleton nucleolus cytoplasm plasma membrane protein complex assembly substrate-bound cell migration, cell extension cell cycle mitosis signal transduction beta-catenin binding actin cytoskeleton cell-cell adhesion cell migration SH3 domain binding endocytic vesicle filamentous actin proteasomal ubiquitin-dependent protein catabolic process cadherin binding regulation of receptor-mediated endocytosis perinuclear region of cytoplasm cell division |
|
229327_s_at |
-0.680 |
7.139 |
-2.391 |
3.013e-02 |
0.540 |
-3.485 |
MAF |
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) |
16 |
-78185246 |
BE674528 |
4094 |
16q22-q23 |
Hs.134859 |
37 |
chromatin cytokine production transcription factor activity RNA polymerase II transcription factor activity protein binding nucleus cytoplasm regulation of transcription, DNA-dependent regulation of chondrocyte differentiation sequence-specific DNA binding positive regulation of transcription from RNA polymerase II promoter cell development lens fiber cell differentiation |
|
203694_s_at |
DHX16 |
DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
6 |
-30728885, -2069456, -1867754 |
NM_003587 |
8449 |
6p21.3 |
Hs.485060 |
9 |
nucleotide binding nucleic acid binding RNA helicase activity ATP binding nucleus mRNA processing ATP-dependent helicase activity RNA splicing hydrolase activity |
|
202353_s_at |
PSMD12 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 |
17 |
-62767081, -62767080 |
NM_002816 |
5718 |
17q24.2 |
Hs.646575 |
39 |
protein binding cytosol proteasome regulatory particle anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
Proteasome |
218649_x_at |
SDCCAG1 |
serologically defined colon cancer antigen 1 |
14 |
-49320281 |
NM_004713 |
9147 |
14q22 |
Hs.655964 |
8 |
nucleus cytoplasm |
|
202057_at |
KPNA1 |
karyopherin alpha 1 (importin alpha 5) |
3 |
-123623437 |
BC002374 |
3836 |
3q21 |
Hs.161008 |
92 |
regulation of DNA recombination protein binding nucleus nuclear pore nucleoplasm cytoplasm cytosol NLS-bearing substrate import into nucleus intracellular protein transport nuclear localization sequence binding protein transporter activity interspecies interaction between organisms |
|
1570444_at |
LOC643201 |
hypothetical protein LOC643201 |
5 |
|
BC034407 |
643201 |
5q35.2 |
Hs.390285 |
1 |
|
|
206254_at |
EGF |
epidermal growth factor (beta-urogastrone) |
4 |
111053488 |
NM_001963 |
1950 |
4q25 |
Hs.419815 |
289 |
activation of MAPKK activity angiogenesis epidermal growth factor receptor binding calcium ion binding protein binding extracellular region extracellular space plasma membrane DNA replication signal transduction epidermal growth factor receptor signaling pathway growth factor activity integral to membrane positive regulation of granule cell precursor proliferation transmembrane receptor protein tyrosine kinase activator activity platelet alpha granule lumen positive regulation of phosphorylation positive regulation of MAP kinase activity positive regulation of epidermal growth factor receptor activity positive regulation of mitosis branching morphogenesis of a tube regulation of protein secretion regulation of peptidyl-tyrosine phosphorylation negative regulation of secretion |
MAPK signaling pathway ErbB signaling pathway Cytokine-cytokine receptor interaction Endocytosis Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Non-small cell lung cancer |
224963_at |
SLC26A2 |
solute carrier family 26 (sulfate transporter), member 2 |
5 |
149320492 |
AK025078 |
1836 |
5q31-q34 |
Hs.302738 |
24 |
transporter activity membrane fraction integral to plasma membrane transport secondary active sulfate transmembrane transporter activity sulfate transport membrane |
|
209145_s_at |
CBFA2T2 |
core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
20 |
31541588, 31613831 |
AF068266 |
9139 |
20q11 |
Hs.153934 |
19 |
transcription factor activity transcription corepressor activity protein binding nucleus zinc ion binding epithelial cell differentiation negative regulation of transcription, DNA-dependent metal ion binding |
|
226764_at |
ZNF827 |
zinc finger protein 827 |
4 |
-146901337 |
BG542955 |
152485 |
4q31.21-q31.22 |
Hs.133916 Hs.633543 |
7 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
208115_x_at |
C10orf137 |
chromosome 10 open reading frame 137 |
10 |
127398073 |
NM_030897 |
26098 |
10q26.13 |
Hs.468688 |
4 |
nucleus regulation of transcription |
|
225659_at |
SPOPL |
speckle-type POZ protein-like |
2 |
138975819 |
BF516590 |
339745 |
2q22.1 |
Hs.333297 |
6 |
protein binding nucleus modification-dependent protein catabolic process |
|
215266_at |
DNAH3 |
dynein, axonemal, heavy chain 3 |
16 |
-20851976 |
AL096732 |
55567 |
16p12.3 |
Hs.526500 |
7 |
nucleotide binding ciliary or flagellar motility microtubule motor activity ATP binding axonemal dynein complex microtubule cilium microtubule-based movement ATPase activity cilium axoneme |
Huntington's disease |
226293_at |
0.335 |
6.221 |
2.971 |
9.410e-03 |
0.401 |
-2.504 |
MED19 |
mediator complex subunit 19 |
11 |
-57227762 |
BE781103 |
219541 |
11q12.1 |
Hs.43619 |
9 |
protein binding nucleus regulation of transcription from RNA polymerase II promoter RNA polymerase II transcription mediator activity regulation of transcription |
|
230619_at |
0.358 |
6.369 |
3.650 |
2.323e-03 |
0.283 |
-1.314 |
ARNT |
aryl hydrocarbon receptor nuclear translocator |
1 |
-149048809 |
AI768497 |
405 |
1q21 |
Hs.632446 |
88 |
response to hypoxia positive regulation of endothelial cell proliferation RNA polymerase II transcription factor activity, enhancer binding transcription coactivator activity signal transducer activity nucleus regulation of transcription, DNA-dependent signal transduction positive regulation vascular endothelial growth factor production aryl hydrocarbon receptor binding positive regulation of vascular endothelial growth factor receptor signaling pathway mRNA transcription from RNA polymerase II promoter positive regulation of gene-specific transcription sequence-specific DNA binding regulation of transcription from RNA polymerase II promoter in response to oxidative stress positive regulation of erythrocyte differentiation positive regulation of glycolysis positive regulation of hormone biosynthetic process protein heterodimerization activity |
Pathways in cancer Renal cell carcinoma |
1569300_at |
MFAP3L |
microfibrillar-associated protein 3-like |
4 |
-171144322, -171144322 |
BG718733 |
9848 |
4q32.3 |
Hs.593942 |
3 |
plasma membrane integral to membrane |
|
217543_s_at |
MBTPS1 |
membrane-bound transcription factor peptidase, site 1 |
16 |
-82644869 |
BE890314 |
8720 |
16 16q24 |
Hs.75890 |
24 |
serine-type endopeptidase activity calcium ion binding nucleus endoplasmic reticulum endoplasmic reticulum lumen Golgi apparatus Golgi stack proteolysis lipid metabolic process steroid metabolic process cholesterol metabolic process peptidase activity membrane integral to membrane regulation of transcription factor import into nucleus |
|
1553316_at |
GPR82 |
G protein-coupled receptor 82 |
X |
41468351 |
NM_080817 |
27197 |
Xp11.4 |
Hs.664795 |
4 |
receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane |
|
231675_s_at |
ADH4 |
alcohol dehydrogenase 4 (class II), pi polypeptide |
4 |
-100263855 |
AV650931 |
127 |
4q21-q24 4q22 |
Hs.1219 |
30 |
NADPH:quinone reductase activity alcohol dehydrogenase activity, zinc-dependent aldehyde reductase activity retinol dehydrogenase activity binding all-trans retinal binding cellular_component cytoplasm ethanol oxidation cellular aldehyde metabolic process zinc ion binding oxidoreductase activity benzaldehyde dehydrogenase activity retinol binding quinone cofactor metabolic process retinol metabolic process alcohol catabolic process metal ion binding NAD or NADH binding oxidation reduction |
Glycolysis / Gluconeogenesis Fatty acid metabolism Tyrosine metabolism 1- and 2-Methylnaphthalene degradation 3-Chloroacrylic acid degradation Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways |
205972_at |
SLC38A3 |
solute carrier family 38, member 3 |
3 |
50217695 |
NM_006841 |
10991 |
3p21.3 |
Hs.76460 |
16 |
L-histidine transmembrane transporter activity plasma membrane integral to plasma membrane ion transport sodium ion transport amino acid transport asparagine transport glutamine transport L-alanine transmembrane transporter activity L-asparagine transmembrane transporter activity L-glutamine transmembrane transporter activity symporter activity antiporter activity L-alanine transport histidine transport sodium ion binding |
|
224215_s_at |
DLL1 |
delta-like 1 (Drosophila) |
6 |
-170433218 |
AF196571 |
28514 |
6q27 |
Hs.379912 |
42 |
cell fate determination somite specification Notch binding calcium ion binding protein binding extracellular region plasma membrane integral to plasma membrane cell communication Notch signaling pathway multicellular organismal development determination of left/right symmetry compartment specification hemopoiesis regulation of cell adhesion cytoplasmic vesicle negative regulation of cell differentiation negative regulation of auditory receptor cell differentiation inner ear development |
Notch signaling pathway |
228420_at |
-0.239 |
5.780 |
-2.935 |
1.012e-02 |
0.415 |
-2.566 |
PDCD2 |
programmed cell death 2 |
6 |
-170732759, -170728374 |
AW590850 |
5134 |
6q27 |
Hs.367900 |
14 |
DNA binding protein binding nucleus cytoplasm apoptosis zinc ion binding metal ion binding |
|
202237_at |
1.698 |
6.714 |
2.194 |
4.416e-02 |
0.579 |
-3.802 |
NNMT |
nicotinamide N-methyltransferase |
11 |
113671744 |
NM_006169 |
4837 |
11q23.1 |
Hs.503911 |
31 |
cytoplasm nicotinamide N-methyltransferase activity methyltransferase activity transferase activity |
Nicotinate and nicotinamide metabolism Metabolic pathways |
205235_s_at |
KIF20B |
kinesin family member 20B |
10 |
91451346 |
NM_016195 |
9585 |
10q23.31 |
Hs.240 |
10 |
nucleotide binding microtubule motor activity ATP binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm centrosome centrosome microtubule microtubule-based movement cell cycle cell cycle arrest regulation of mitosis ATPase activity ATPase activity WW domain binding WW domain binding cell division |
|
1553681_a_at |
PRF1 |
perforin 1 (pore forming protein) |
10 |
-72027109 |
NM_005041 |
5551 |
10q22 |
Hs.2200 |
88 |
calcium ion binding apoptosis cellular defense response circadian rhythm pathogenesis membrane integral to membrane cytoplasmic membrane-bounded vesicle cytolysis response to ethanol |
Natural killer cell mediated cytotoxicity Type I diabetes mellitus Autoimmune thyroid disease Allograft rejection Graft-versus-host disease |
244840_x_at |
DOCK4 |
dedicator of cytokinesis 4 |
7 |
-111153399 |
AW452588 |
9732 |
7q31.1 |
Hs.654652 |
16 |
guanyl-nucleotide exchange factor activity protein binding membrane SH3 domain binding PDZ domain binding Rac GTPase activator activity stereocilium Rac GTPase binding |
|
241990_at |
RHOV |
ras homolog gene family, member V |
15 |
-38951704 |
BE547917 |
171177 |
15q13.3 |
Hs.447901 |
7 |
nucleotide binding magnesium ion binding protein binding GTP binding intracellular endosome plasma membrane small GTPase mediated signal transduction |
|
218008_at |
C7orf42 |
chromosome 7 open reading frame 42 |
7 |
66023637 |
NM_017994 |
55069 |
7q11.21 |
Hs.488478 |
5 |
membrane integral to membrane |
|
232593_at |
NEURL3 |
neuralized homolog 3 (Drosophila) pseudogene |
2 |
-96527111 |
AL389981 |
93082 |
2q11.2 |
Hs.149219 |
3 |
protein binding zinc ion binding ligase activity modification-dependent protein catabolic process metal ion binding |
|
216055_at |
PDGFB |
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) |
22 |
-37949632, -37949632 |
AK022920 |
5155 |
22q12.3-q13.1 22q13.1 |
Hs.1976 |
140 |
response to hypoxia positive regulation of endothelial cell proliferation monocyte chemotaxis platelet-derived growth factor receptor binding collagen binding extracellular region extracellular region cytoplasm substrate-bound cell migration transforming growth factor beta receptor signaling pathway growth factor activity response to wounding cell surface negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation positive regulation of smooth muscle cell migration membrane cell growth cell projection assembly actin cytoskeleton organization negative regulation of cell migration platelet dense granule lumen protein homodimerization activity positive regulation of MAP kinase activity cell surface binding positive regulation of blood vessel endothelial cell migration positive regulation of DNA replication protein heterodimerization activity platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation platelet-derived growth factor binding regulation of peptidyl-tyrosine phosphorylation positive regulation of chemotaxis cell chemotaxis |
MAPK signaling pathway Cytokine-cytokine receptor interaction Focal adhesion Gap junction Regulation of actin cytoskeleton Pathways in cancer Renal cell carcinoma Glioma Prostate cancer Melanoma |
206147_x_at |
SCML2 |
sex comb on midleg-like 2 (Drosophila) |
X |
-18167353 |
NM_006089 |
10389 |
Xp22 |
Hs.495774 |
7 |
transcription factor activity nucleus anatomical structure morphogenesis regulation of transcription |
|
211534_x_at |
PTPRN2 |
protein tyrosine phosphatase, receptor type, N polypeptide 2 |
7 |
-157024510 |
U65065 |
5799 |
7q36 |
Hs.490789 Hs.715864 Hs.716042 |
19 |
receptor activity transmembrane receptor protein tyrosine phosphatase activity protein binding integral to plasma membrane protein amino acid dephosphorylation membrane hydrolase activity |
Type I diabetes mellitus |
209168_at |
GPM6B |
glycoprotein M6B |
X |
-13702017, -13702017, -13698982 |
AW148844 |
2824 |
Xp22.2 |
Hs.495710 |
17 |
molecular_function multicellular organismal development nervous system development membrane integral to membrane cell differentiation |
|
209621_s_at |
PDLIM3 |
PDZ and LIM domain 3 |
4 |
-186659844 |
AF002280 |
27295 |
4q35 |
Hs.85862 |
12 |
nucleus nucleolus cytoplasm actin filament organization heart development cytoskeletal protein binding zinc ion binding structural constituent of muscle actin cytoskeleton Z disc metal ion binding |
|
211469_s_at |
CXCR6 |
chemokine (C-X-C motif) receptor 6 |
3 |
45959976 |
U73531 |
10663 |
3p21 |
Hs.34526 |
37 |
G-protein coupled receptor activity plasma membrane integral to plasma membrane signal transduction G-protein coupled receptor protein signaling pathway coreceptor activity C-C chemokine receptor activity C-X-C chemokine receptor activity viral genome replication |
Cytokine-cytokine receptor interaction Chemokine signaling pathway |
223026_s_at |
0.264 |
10.108 |
2.199 |
4.371e-02 |
0.578 |
-3.793 |
VPS29 |
vacuolar protein sorting 29 homolog (S. cerevisiae) |
12 |
-109413712 |
AF201946 |
51699 |
12q24 |
Hs.600114 |
17 |
phosphoserine phosphatase activity cytoplasm endosome zinc ion binding protein transport membrane hydrolase activity metal ion binding |
|
213733_at |
MYO1F |
myosin IF |
19 |
-8491996 |
BF740152 |
4542 |
19p13.3-p13.2 |
Hs.465818 |
11 |
nucleotide binding motor activity actin binding calmodulin binding ATP binding negative regulation of cell adhesion biological_process unconventional myosin complex positive regulation of cell migration cortical actin cytoskeleton filamentous actin regulation of actin cytoskeleton organization neutrophil degranulation regulation of innate immune response defense response to Gram-positive bacterium |
|
220529_at |
FLJ11710 |
hypothetical protein FLJ11710 |
17 |
|
NM_024846 |
79904 |
17q23.2 |
Hs.657294 |
1 |
|
|
227251_at |
DCAF5 |
DDB1 and CUL4 associated factor 5 |
14 |
-68587390 |
AI431597 |
8816 |
14q23-q24.1 |
Hs.509780 |
6 |
|
|
227256_at |
USP31 |
ubiquitin specific peptidase 31 |
16 |
-22980228 |
BG289456 |
57478 |
16p12.2 |
Hs.183817 |
8 |
ubiquitin thiolesterase activity ubiquitin-dependent protein catabolic process peptidase activity cysteine-type peptidase activity |
|
1553718_at |
ZNF548 |
zinc finger protein 548 |
19 |
62593029 |
NM_152909 |
147694 |
19q13.43 |
Hs.657353 |
3 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
225951_s_at |
0.380 |
8.993 |
2.333 |
3.374e-02 |
0.552 |
-3.579 |
CHD2 |
chromodomain helicase DNA binding protein 2 |
15 |
91244554, 91244554 |
AV756026 |
1106 |
15q26 |
Hs.220864 |
9 |
nucleotide binding chromatin DNA binding chromatin binding ATP-dependent DNA helicase activity helicase activity ATP binding nucleus chromatin assembly or disassembly regulation of transcription from RNA polymerase II promoter hydrolase activity |
|
208218_s_at |
ACVR1B |
activin A receptor, type IB |
12 |
50631752, 50631752, 50631752 |
NM_020328 |
91 |
12q13 |
Hs.438918 |
39 |
G1/S transition of mitotic cell cycle nucleotide binding magnesium ion binding in utero embryonic development hair follicle development protein serine/threonine kinase activity receptor activity ATP binding integral to plasma membrane induction of apoptosis signal transduction transmembrane receptor protein serine/threonine kinase signaling pathway embryonic development cell surface membrane activin receptor activity, type I transferase activity peptidyl-threonine phosphorylation growth factor binding manganese ion binding negative regulation of cell growth ubiquitin protein ligase binding positive regulation of activin receptor signaling pathway regulation of transcription positive regulation of erythrocyte differentiation SMAD binding protein amino acid autophosphorylation activin binding |
MAPK signaling pathway Cytokine-cytokine receptor interaction Endocytosis TGF-beta signaling pathway Adherens junction Pathways in cancer Colorectal cancer Pancreatic cancer Chronic myeloid leukemia |
228369_at |
CNPY3 |
canopy 3 homolog (zebrafish) |
6 |
43004837 |
AI262560 |
10695 |
6pter-p12.1 |
Hs.414099 |
6 |
receptor binding extracellular region |
|
201172_x_at |
0.251 |
9.756 |
2.845 |
1.215e-02 |
0.426 |
-2.721 |
ATP6V0E1 |
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
5 |
172343368 |
NM_003945 |
8992 |
5q35.1 |
Hs.484188 |
18 |
transporter activity membrane fraction ion transport vacuolar acidification ATP synthesis coupled proton transport ATP hydrolysis coupled proton transport proton transport membrane integral to membrane cell growth hydrolase activity proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions proton-transporting ATPase activity, rotational mechanism |
Oxidative phosphorylation Metabolic pathways Vibrio cholerae infection Epithelial cell signaling in Helicobacter pylori infection |
244759_x_at |
RNF207 |
ring finger protein 207 |
1 |
6188775 |
AI219323 |
388591 |
1p36.31 |
Hs.716549 |
7 |
protein binding intracellular zinc ion binding metal ion binding |
|
208055_s_at |
HERC4 |
hect domain and RLD 4 |
10 |
-69351661 |
NM_015601 |
26091 |
10q21.3 |
Hs.51891 |
7 |
intracellular cytoplasm cytosol protein modification process ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process |
Ubiquitin mediated proteolysis |
216903_s_at |
CBARA1 |
calcium binding atopy-related autoantigen 1 |
10 |
-73797103 |
AK022697 |
10367 |
10q22.1 |
Hs.524367 |
7 |
calcium ion binding intracellular defense response membrane integral to membrane |
|
231228_at |
BCL2L1 |
BCL2-like 1 |
20 |
-29715921 |
AW263226 |
598 |
20q11.21 |
Hs.516966 |
295 |
release of cytochrome c from mitochondria nucleus mitochondrion mitochondrial outer membrane mitochondrial outer membrane anti-apoptosis negative regulation of survival gene product expression membrane integral to membrane response to cytokine stimulus identical protein binding regulation of mitochondrial membrane permeability regulation of mitochondrial membrane potential |
Apoptosis Jak-STAT signaling pathway Amyotrophic lateral sclerosis (ALS) Pathways in cancer Pancreatic cancer Chronic myeloid leukemia Small cell lung cancer |
210616_s_at |
0.320 |
8.298 |
2.245 |
4.001e-02 |
0.568 |
-3.720 |
SEC31A |
SEC31 homolog A (S. cerevisiae) |
4 |
-83958837 |
AB020712 |
22872 |
4q21.22 |
Hs.370024 |
20 |
cytoplasm endoplasmic reticulum ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport protein transport membrane membrane organization vesicle-mediated transport COPII vesicle coat cytoplasmic vesicle calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion |
|
239894_at |
LOC100128511 |
hypothetical LOC100128511 |
10 |
|
AW204239 |
100128511 |
10p12.31 |
|
|
|
|
209305_s_at |
GADD45B |
growth arrest and DNA-damage-inducible, beta |
19 |
2427134 |
AF078077 |
4616 |
19p13.3 |
Hs.110571 |
33 |
activation of MAPKKK activity activation of MAPKK activity protein binding negative regulation of protein kinase activity apoptosis response to stress multicellular organismal development cell differentiation regulation of cell cycle |
MAPK signaling pathway Cell cycle p53 signaling pathway |
227109_at |
CYP2R1 |
cytochrome P450, family 2, subfamily R, polypeptide 1 |
11 |
-14856131 |
AV700558 |
120227 |
11p15.2 |
Hs.371427 |
13 |
monooxygenase activity endoplasmic reticulum microsome electron carrier activity membrane heme binding metal ion binding cholestanetriol 26-monooxygenase activity oxidation reduction |
|
220004_at |
DDX43 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
6 |
74161005 |
NM_018665 |
55510 |
6q12-q13 |
Hs.125507 |
12 |
nucleotide binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding intracellular hydrolase activity |
|
217173_s_at |
LDLR |
low density lipoprotein receptor |
19 |
11061056 |
S70123 |
3949 |
19p13.3 |
Hs.213289 Hs.713967 |
374 |
transmembrane receptor activity low-density lipoprotein receptor activity calcium ion binding endosome plasma membrane plasma membrane integral to plasma membrane coated pit protein amino acid O-linked glycosylation lipid metabolic process lipid transport endocytosis steroid metabolic process cholesterol metabolic process endosome membrane very-low-density lipoprotein receptor activity intestinal cholesterol absorption clathrin-coated endocytic vesicle membrane low-density lipoprotein particle low-density lipoprotein particle clearance lipoprotein catabolic process cholesterol homeostasis interspecies interaction between organisms |
Endocytosis |
227205_at |
TAF1 |
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
X |
70502838 |
AW575233 |
6872 |
Xq13.1 |
Hs.158560 |
110 |
G1 phase of mitotic cell cycle regulation of transcription during G2/M-phase of mitotic cell cycle nucleotide binding p53 binding transcription coactivator activity histone acetyltransferase activity protein serine/threonine kinase activity ATP binding nucleus nucleoplasm transcription factor TFIID complex nucleolus regulation of transcription, DNA-dependent RNA elongation from RNA polymerase II promoter cell cycle transcription factor binding positive regulation of specific transcription from RNA polymerase II promoter promoter binding kinase activity transferase activity transcription initiation factor activity TATA-binding protein binding peptidyl-serine phosphorylation peptidyl-threonine phosphorylation positive regulation of proteasomal ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus interspecies interaction between organisms protein amino acid autophosphorylation transcriptional preinitiation complex assembly positive regulation of transcription initiation from RNA polymerase II promoter histone acetyl-lysine binding |
Basal transcription factors |
230071_at |
SEPT11 |
septin 11 |
4 |
78089918 |
AI333326 |
55752 |
4q21.1 |
Hs.128199 |
16 |
nucleotide binding stress fiber protein binding GTP binding cell cycle septin complex protein heterooligomerization cell division |
|
207355_at |
SLC1A7 |
solute carrier family 1 (glutamate transporter), member 7 |
1 |
-53325442 |
NM_006671 |
6512 |
1p32.3 |
Hs.104637 Hs.716133 |
6 |
L-glutamate transmembrane transporter activity transport dicarboxylic acid transport symporter activity membrane integral to membrane sodium:dicarboxylate symporter activity |
|
1556285_s_at |
PPA2 |
pyrophosphatase (inorganic) 2 |
4 |
-106509682 |
AF086012 |
27068 |
4q25 |
Hs.654957 |
13 |
magnesium ion binding inorganic diphosphatase activity cytoplasm mitochondrion phosphate metabolic process hydrolase activity |
Oxidative phosphorylation |
77508_r_at |
RABEP2 |
rabaptin, RAB GTPase binding effector protein 2 |
16 |
-28823242 |
AW001436 |
79874 |
16p11.2 |
Hs.555978 |
6 |
GTPase activator activity cytoplasm early endosome endocytosis growth factor activity protein transport |
|
202691_at |
SNRPD1 |
small nuclear ribonucleoprotein D1 polypeptide 16kDa |
18 |
17446257 |
NM_006938 |
6632 |
18q11.2 |
Hs.464734 |
38 |
spliceosome assembly spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm spliceosomal complex cytoplasm cytosol RNA splicing small nuclear ribonucleoprotein complex |
Systemic lupus erythematosus |
244103_at |
C1orf55 |
chromosome 1 open reading frame 55 |
1 |
-224237025 |
AW963092 |
163859 |
1q42.12 |
Hs.520192 |
2 |
|
|
226676_at |
0.657 |
4.388 |
4.757 |
2.451e-04 |
0.172 |
0.576 |
ZNF521 |
zinc finger protein 521 |
18 |
-20895885 |
AK021452 |
25925 |
18q11.2 |
Hs.116935 |
9 |
|
|
224413_s_at |
0.330 |
7.148 |
2.289 |
3.679e-02 |
0.561 |
-3.651 |
TM2D2 |
TM2 domain containing 2 |
8 |
-38965483 |
AF353991 |
83877 |
8p11.22 |
Hs.7471 |
5 |
membrane integral to membrane |
|
210399_x_at |
-0.284 |
6.170 |
-2.551 |
2.198e-02 |
0.499 |
-3.221 |
FUT6 |
fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
19 |
-5781636 |
U27336 |
2528 |
19p13.3 |
Hs.631846 Hs.705615 |
19 |
Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity |
Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
210039_s_at |
PRKCQ |
protein kinase C, theta |
10 |
-6509110 |
L01087 |
5588 |
10p15 |
Hs.498570 |
112 |
nucleotide binding magnesium ion binding regulation of cell growth protein kinase C activity protein binding ATP binding intracellular protein amino acid phosphorylation membrane protein ectodomain proteolysis intracellular signaling cascade zinc ion binding transferase activity diacylglycerol binding |
Vascular smooth muscle contraction Tight junction T cell receptor signaling pathway Adipocytokine signaling pathway |
222735_at |
TMEM38B |
transmembrane protein 38B |
9 |
107496645 |
AW452608 |
55151 |
9q31.2 |
Hs.411925 |
5 |
potassium channel activity endoplasmic reticulum ion transport potassium ion transport membrane integral to membrane potassium ion binding nuclear membrane sarcoplasmic reticulum membrane |
|
223037_at |
0.493 |
7.586 |
2.867 |
1.163e-02 |
0.426 |
-2.684 |
PDZD11 |
PDZ domain containing 11 |
X |
-69422935 |
AF151061 |
51248 |
Xq13.1 |
Hs.11042 |
12 |
protein binding extracellular region |
|
231854_at |
PIK3CA |
phosphoinositide-3-kinase, catalytic, alpha polypeptide |
3 |
180349004 |
W63579 |
5290 |
3q26.3 |
Hs.553498 Hs.85701 |
259 |
nucleotide binding inositol or phosphatidylinositol kinase activity ATP binding cytosol phosphoinositide 3-kinase complex glucose metabolic process protein amino acid phosphorylation anti-apoptosis signal transduction 1-phosphatidylinositol-3-kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor lamellipodium regulation of multicellular organism growth protein kinase B signaling cascade insulin receptor substrate binding phosphoinositide phosphorylation phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphoinositide-mediated signaling |
Inositol phosphate metabolism ErbB signaling pathway Chemokine signaling pathway Phosphatidylinositol signaling system mTOR signaling pathway Apoptosis VEGF signaling pathway Focal adhesion Toll-like receptor signaling pathway Jak-STAT signaling pathway Natural killer cell mediated cytotoxicity T cell receptor signaling pathway B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Insulin signaling pathway Type II diabetes mellitus Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Chronic myeloid leukemia Acute myeloid leukemia Small cell lung cancer Non-small cell lung cancer |
213346_at |
C13orf27 |
chromosome 13 open reading frame 27 |
13 |
-102216465 |
BE748563 |
93081 |
13q33.1 |
Hs.398111 |
6 |
|
|
235747_at |
SLC25A16 |
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 |
10 |
-69912102 |
AI305170 |
8034 |
10q21.3 |
Hs.180408 |
6 |
binding mitochondrion mitochondrial inner membrane transport solute:solute antiporter activity membrane integral to membrane |
|
235810_at |
ZNF182 |
zinc finger protein 182 |
X |
-47719193 |
AI225224 |
7569 |
Xp22.11-p11.23 |
Hs.189690 |
8 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
214805_at |
0.472 |
5.588 |
3.638 |
2.381e-03 |
0.284 |
-1.335 |
EIF4A1 |
eukaryotic translation initiation factor 4A, isoform 1 |
17 |
7416780 |
U79273 |
1973 |
17p13 |
Hs.129673 |
28 |
nucleotide binding RNA cap binding mRNA binding translation initiation factor activity helicase activity protein binding ATP binding cytosol translation ATP-dependent helicase activity eukaryotic translation initiation factor 4F complex hydrolase activity |
|
230425_at |
EPHB1 |
EPH receptor B1 |
3 |
135996949 |
AI674183 |
2047 |
3q21-q23 |
Hs.116092 |
41 |
nucleotide binding receptor activity ephrin receptor activity protein binding ATP binding plasma membrane integral to plasma membrane protein amino acid phosphorylation signal transduction transmembrane receptor protein tyrosine kinase signaling pathway nervous system development transferase activity |
Axon guidance |
233499_at |
LRRC7 |
leucine rich repeat containing 7 |
1 |
69998445 |
AI366175 |
57554 |
1p31.1 |
Hs.479658 |
16 |
protein binding nucleus nucleolus cytoplasm plasma membrane focal adhesion |
|
208641_s_at |
RAC1 |
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
7 |
6380650 |
BC004247 |
5879 |
7p22 |
Hs.413812 |
406 |
nucleotide binding GTPase activity GTP binding intracellular cytosol plasma membrane cell motion inflammatory response cell adhesion small GTPase mediated signal transduction anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly enzyme binding actin filament polymerization GTP-dependent protein binding ruffle organization positive regulation of Rho protein signal transduction melanosome negative regulation of receptor-mediated endocytosis localization within membrane regulation of respiratory burst |
MAPK signaling pathway Chemokine signaling pathway Wnt signaling pathway Axon guidance VEGF signaling pathway Focal adhesion Adherens junction Toll-like receptor signaling pathway Natural killer cell mediated cytotoxicity B cell receptor signaling pathway Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Neurotrophin signaling pathway Regulation of actin cytoskeleton Amyotrophic lateral sclerosis (ALS) Epithelial cell signaling in Helicobacter pylori infection Pathways in cancer Colorectal cancer Renal cell carcinoma Pancreatic cancer |
204444_at |
KIF11 |
kinesin family member 11 |
10 |
94342804 |
NM_004523 |
3832 |
10q24.1 |
Hs.8878 |
43 |
nucleotide binding spindle pole microtubule motor activity ATP binding kinesin complex spindle microtubule microtubule-based movement cell cycle mitotic spindle organization mitosis mitotic centrosome separation chromatin remodeling complex spindle pole body organization cell division |
|
223598_at |
RAD23B |
RAD23 homolog B (S. cerevisiae) |
9 |
109085364 |
AF262027 |
5887 |
9q31.2 |
Hs.521640 |
54 |
nucleotide-excision repair, DNA damage removal damaged DNA binding single-stranded DNA binding protein binding nucleus nucleoplasm cytoplasm cytosol response to DNA damage stimulus modification-dependent protein catabolic process proteasomal ubiquitin-dependent protein catabolic process protein complex |
Nucleotide excision repair |
231978_at |
0.379 |
3.703 |
3.009 |
8.694e-03 |
0.393 |
-2.437 |
TPCN2 |
two pore segment channel 2 |
11 |
68572925 |
AL137479 |
219931 |
11q13.3 |
Hs.131851 |
9 |
voltage-gated ion channel activity calcium channel activity calcium ion binding ion transport calcium ion transport membrane integral to membrane |
|
214060_at |
SSBP1 |
single-stranded DNA binding protein 1 |
7 |
141084644 |
BE220360 |
6742 |
7q34 |
Hs.490394 |
21 |
DNA binding single-stranded DNA binding mitochondrion DNA replication mitochondrial nucleoid positive regulation of helicase activity |
DNA replication Mismatch repair Homologous recombination |
219972_s_at |
C14orf135 |
chromosome 14 open reading frame 135 |
14 |
59628381 |
NM_022495 |
64430 |
14q23.1 |
Hs.509499 |
7 |
membrane integral to membrane |
|
235900_at |
SPNS3 |
spinster homolog 3 (Drosophila) |
17 |
4283967 |
AW016030 |
201305 |
17p13.2 |
Hs.657543 |
2 |
lipid transport membrane integral to membrane |
|
212236_x_at |
KRT17 |
keratin 17 |
17 |
-37029217 |
Z19574 |
3872 |
17q12-q21 |
Hs.2785 |
39 |
structural constituent of cytoskeleton protein binding nucleus nucleolus cytoplasm cytoskeleton intermediate filament epidermis development |
|
1560514_at |
-0.265 |
3.903 |
-2.601 |
1.987e-02 |
0.491 |
-3.137 |
LOC285205 |
hypothetical LOC285205 |
3 |
109084741 |
BC039517 |
285205 |
3q13.12 |
Hs.134882 |
2 |
|
|
1557682_a_at |
RP11-297H3.4 |
hypothetical LOC284688 |
1 |
-168507169 |
BG150294 |
284688 |
1q24.2 |
Hs.135668 |
2 |
|
|
218848_at |
THOC6 |
THO complex 6 homolog (Drosophila) |
16 |
3014032 |
NM_024339 |
79228 |
16p13.3 |
Hs.412304 |
2 |
|
|
226337_at |
GORAB |
golgin, RAB6-interacting |
1 |
168767886, 168767886 |
AK021814 |
92344 |
1q24.2 |
Hs.183702 |
7 |
protein binding cytoplasm Golgi apparatus |
|
207676_at |
ONECUT2 |
one cut homeobox 2 |
18 |
53253914 |
NM_004852 |
9480 |
18q21.1-q21.2 |
Hs.194725 |
7 |
liver development regulation of cell-matrix adhesion epithelial cell development transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription, DNA-dependent organ morphogenesis positive regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway endocrine pancreas development cilium assembly sequence-specific DNA binding cell fate commitment positive regulation of transcription from RNA polymerase II promoter peripheral nervous system neuron development |
|
206614_at |
-0.323 |
5.363 |
-3.324 |
4.553e-03 |
0.332 |
-1.887 |
GDF5 |
growth differentiation factor 5 |
20 |
-33484562 |
NM_000557 |
8200 |
20q11.2 |
Hs.1573 |
58 |
cytokine activity protein binding extracellular region extracellular space transforming growth factor beta receptor signaling pathway cell-cell signaling growth factor activity embryonic limb morphogenesis positive regulation of chondrocyte differentiation post-embryonic hindlimb morphogenesis forelimb morphogenesis growth regulation of multicellular organism growth regulation of apoptosis |
Cytokine-cytokine receptor interaction TGF-beta signaling pathway |
1561589_a_at |
0.328 |
2.975 |
2.746 |
1.485e-02 |
0.453 |
-2.891 |
NBEAL1 |
neurobeachin-like 1 |
2 |
203587846, 203708717 |
AB053319 |
65065 |
2q33.2 |
Hs.604686 Hs.648846 |
6 |
|
|
226703_at |
NEURL4 |
neuralized homolog 4 (Drosophila) |
17 |
-7159674 |
AL136870 |
84461 |
17p13 |
Hs.654794 |
3 |
protein binding |
|
216442_x_at |
0.943 |
9.123 |
3.371 |
4.131e-03 |
0.323 |
-1.804 |
FN1 |
fibronectin 1 |
2 |
-215987628, -215933423 |
AK026737 |
2335 |
2q34 |
Hs.203717 |
291 |
extracellular matrix structural constituent collagen binding extracellular region extracellular region fibrinogen complex proteinaceous extracellular matrix ER-Golgi intermediate compartment acute-phase response cell adhesion heparin binding regulation of cell shape response to wounding cell migration peptide cross-linking platelet alpha granule lumen substrate adhesion-dependent cell spreading |
Focal adhesion ECM-receptor interaction Regulation of actin cytoskeleton Pathways in cancer Small cell lung cancer |
230385_at |
MARCH3 |
membrane-associated ring finger (C3HC4) 3 |
5 |
-126231305 |
BF510835 |
115123 |
5q23.2 |
Hs.132441 |
6 |
endosome endocytosis zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process cytoplasmic vesicle metal ion binding |
|
203906_at |
IQSEC1 |
IQ motif and Sec7 domain 1 |
3 |
-12913718, -12913718 |
AI652645 |
9922 |
3p25.2 |
Hs.475506 |
10 |
ARF guanyl-nucleotide exchange factor activity intracellular nucleus cytoplasm regulation of ARF protein signal transduction |
Endocytosis |
234453_s_at |
C14orf166B |
chromosome 14 open reading frame 166B |
14 |
76362477 |
AF111169 |
145497 |
14q24.3 |
Hs.147276 |
2 |
protein binding |
|
1552276_a_at |
-0.294 |
5.144 |
-2.254 |
3.932e-02 |
0.567 |
-3.706 |
VPS18 |
vacuolar protein sorting 18 homolog (S. cerevisiae) |
15 |
38973919 |
NM_080432 |
57617 |
15q14-q15 |
Hs.23876 |
11 |
actin binding protein binding lysosome early endosome actin filament endosome organization lysosome organization zinc ion binding protein transport membrane metal ion binding |
|
221019_s_at |
COLEC12 |
collectin sub-family member 12 |
18 |
-309355 |
NM_030781 |
81035 |
18pter-p11.3 |
Hs.464422 |
8 |
scavenger receptor activity binding calcium ion binding sugar binding galactose binding phagocytosis, recognition pattern recognition receptor activity carbohydrate mediated signaling membrane integral to membrane low-density lipoprotein binding innate immune response protein homooligomerization |
|
213844_at |
HOXA5 |
homeobox A5 |
7 |
-27147520 |
NM_019102 |
3202 |
7p15-p14 |
Hs.655218 |
32 |
transcription factor activity nucleus regulation of transcription, DNA-dependent pattern specification process anterior/posterior pattern formation lung development thyroid gland development multicellular organism growth sequence-specific DNA binding embryonic skeletal system morphogenesis |
|
203130_s_at |
KIF5C |
kinesin family member 5C |
2 |
149349288 |
NM_004522 |
3800 |
2q23.1 |
Hs.435557 Hs.660699 |
15 |
nucleotide binding microtubule motor activity protein binding ATP binding kinesin complex microtubule organelle organization microtubule-based movement |
|
213311_s_at |
TCF25 |
transcription factor 25 (basic helix-loop-helix) |
16 |
88467494 |
BF000251 |
22980 |
16q24.3 |
Hs.415342 |
9 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity protein binding nucleus heart development regulation of transcription |
|
208660_at |
CS |
citrate synthase |
12 |
-54951749 |
BC000105 |
1431 |
12q13.2-q13.3 |
Hs.430606 Hs.715526 |
20 |
citrate (Si)-synthase activity citrate (Si)-synthase activity mitochondrion mitochondrial matrix mitochondrial matrix tricarboxylic acid cycle transferase activity cellular carbohydrate metabolic process |
Citrate cycle (TCA cycle) Glyoxylate and dicarboxylate metabolism Biosynthesis of phenylpropanoids Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Biosynthesis of plant hormones Metabolic pathways |
210946_at |
PPAP2A |
phosphatidic acid phosphatase type 2A |
5 |
-54756439 |
AF014403 |
8611 |
5q11 |
Hs.696231 |
20 |
membrane fraction cytosol plasma membrane integral to plasma membrane activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity negative regulation of cell proliferation germ cell migration hydrolase activity regulation of lipid metabolic process androgen receptor signaling pathway phospholipid dephosphorylation |
Glycerolipid metabolism Glycerophospholipid metabolism Ether lipid metabolism Sphingolipid metabolism Metabolic pathways Fc gamma R-mediated phagocytosis |
215275_at |
TRAF3IP3 |
TRAF3 interacting protein 3 |
1 |
207996146 |
AW963138 |
80342 |
1q32.3-q41 |
Hs.147434 |
11 |
membrane integral to membrane |
|
1569469_a_at |
-0.268 |
2.348 |
-2.267 |
3.842e-02 |
0.565 |
-3.687 |
LHX8 |
LIM homeobox 8 |
1 |
75366706 |
BC040321 |
431707 |
1p31.1 |
Hs.403934 |
8 |
transcription factor activity nucleus regulation of transcription, DNA-dependent learning or memory zinc ion binding female gonad development forebrain neuron development odontogenesis of dentine-containing tooth sequence-specific DNA binding metal ion binding |
|
1555831_s_at |
LRRC41 |
leucine rich repeat containing 41 |
1 |
-46516658 |
BC004948 |
10489 |
1p34.1 |
Hs.144941 |
12 |
modification-dependent protein catabolic process |
|
204181_s_at |
ZBTB43 |
zinc finger and BTB domain containing 43 |
9 |
128607105 |
T90308 |
23099 |
9q33-q34 |
Hs.355581 Hs.718657 |
7 |
DNA binding protein binding intracellular nucleus nucleolus zinc ion binding regulation of transcription metal ion binding |
|
201411_s_at |
PLEKHB2 |
pleckstrin homology domain containing, family B (evectins) member 2 |
2 |
131578889 |
NM_017958 |
55041 |
2q21.1 |
Hs.469944 Hs.711433 |
11 |
protein binding membrane |
|
1553169_at |
LRRN4 |
leucine rich repeat neuronal 4 |
20 |
-5969424 |
BC019612 |
164312 |
20p12.3 |
Hs.149133 Hs.716060 |
6 |
protein binding membrane integral to membrane |
|
211296_x_at |
UBC |
ubiquitin C |
12 |
-123962144 |
AB009010 |
7316 |
12q24.3 |
Hs.520348 |
226 |
|
PPAR signaling pathway |
207810_at |
-0.192 |
2.717 |
-2.194 |
4.420e-02 |
0.579 |
-3.802 |
F13B |
coagulation factor XIII, B polypeptide |
1 |
-195274943 |
NM_001994 |
2165 |
1q31-q32.1 |
Hs.435782 |
43 |
extracellular region extracellular region blood coagulation |
Complement and coagulation cascades |
1553053_at |
-0.196 |
3.668 |
-2.305 |
3.563e-02 |
0.556 |
-3.624 |
C14orf48 |
chromosome 14 open reading frame 48 |
14 |
93533368, 93533394, 93533394 |
NM_152777 |
256369 |
14q32.12 |
Hs.143845 |
5 |
|
|
227441_s_at |
ANKS1B |
ankyrin repeat and sterile alpha motif domain containing 1B |
12 |
-97662124, -97653201, -97653201 |
AW005572 |
56899 |
12q23.1 |
Hs.506458 |
10 |
nucleus cytoplasm plasma membrane postsynaptic density Cajal body cell junction cell projection dendritic spine synapse postsynaptic membrane |
|
211677_x_at |
CADM3 |
cell adhesion molecule 3 |
1 |
157408000, 157408037 |
AF062733 |
57863 |
1q21.2-q22 |
Hs.365689 |
16 |
calcium ion binding protein binding plasma membrane cell-cell junction cell adhesion homophilic cell adhesion heterophilic cell adhesion integral to membrane protein homodimerization activity |
Cell adhesion molecules (CAMs) |
224162_s_at |
FBXO31 |
F-box protein 31 |
16 |
-85920444, -85920444 |
BC002985 |
79791 |
16q24.2 |
Hs.567582 |
10 |
cell cycle cyclin catabolic process SCF ubiquitin ligase complex modification-dependent protein catabolic process cyclin binding SCF-dependent proteasomal ubiquitin-dependent protein catabolic process G1 DNA damage checkpoint cellular response to DNA damage stimulus |
|
207036_x_at |
GRIN2D |
glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
19 |
53589943 |
NM_000836 |
2906 |
19q13.1-qter |
Hs.445015 |
42 |
magnesium ion binding startle response receptor activity N-methyl-D-aspartate selective glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity calcium ion binding protein binding plasma membrane ion transport signal transduction adult locomotory behavior integral to membrane synaptosome cell junction synapse postsynaptic membrane regulation of sensory perception of pain |
Calcium signaling pathway Neuroactive ligand-receptor interaction Long-term potentiation Alzheimer's disease Amyotrophic lateral sclerosis (ALS) |
221729_at |
0.720 |
7.368 |
2.990 |
9.045e-03 |
0.396 |
-2.471 |
COL5A2 |
collagen, type V, alpha 2 |
2 |
-189604885 |
AL575735 |
1290 |
2q14-q32 |
Hs.445827 |
29 |
molecular_function extracellular matrix structural constituent extracellular region collagen collagen type V collagen fibril organization collagen fibril organization skin development skin development eye morphogenesis |
Focal adhesion ECM-receptor interaction |
226037_s_at |
TAF9B |
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
X |
-77271900, 1383006 |
AL049589 |
51616 |
Xq13.1-q21.1 |
Hs.592248 Hs.643614 Hs.714006 |
8 |
DNA binding transcription corepressor activity protein binding nucleus transcription factor TFIID complex transcription initiation negative regulation of specific transcription from RNA polymerase II promoter positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptosis regulation of transcription |
Basal transcription factors |
239831_at |
TMEM106C |
transmembrane protein 106C |
12 |
46643596 |
R19392 |
79022 |
12q13.1 |
Hs.596726 |
5 |
molecular_function cellular_component endoplasmic reticulum biological_process membrane integral to membrane |
|
229328_at |
ZNF540 |
zinc finger protein 540 |
19 |
42734147 |
T90358 |
163255 |
19q13.12 |
Hs.121283 |
5 |
DNA binding intracellular nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
212172_at |
-0.289 |
5.354 |
-2.211 |
4.275e-02 |
0.576 |
-3.775 |
AK2 |
adenylate kinase 2 |
1 |
-33251169, -33246172 |
AW277253 |
204 |
1p34 |
Hs.470907 |
16 |
nucleotide binding adenylate kinase activity ATP binding mitochondrion mitochondrial intermembrane space mitochondrial intermembrane space nucleobase, nucleoside, nucleotide and nucleic acid metabolic process transferase activity nucleoside kinase activity |
Purine metabolism Metabolic pathways |
225868_at |
TRIM47 |
tripartite motif-containing 47 |
17 |
-71381839 |
AW249467 |
91107 |
17q24-q25 |
Hs.293660 |
5 |
protein binding intracellular nucleus cytoplasm zinc ion binding metal ion binding |
|
1557055_s_at |
0.819 |
6.704 |
3.198 |
5.896e-03 |
0.357 |
-2.107 |
LOC643837 |
hypothetical LOC643837 |
1 |
752926 |
BC042880 |
643837 |
1p36.33 |
Hs.133183 |
2 |
|
|
234107_s_at |
DTD1 |
D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae) |
20 |
18516555 |
AL121780 |
92675 |
20p11.23 |
Hs.659442 |
7 |
cytoplasm hydrolase activity, acting on ester bonds D-amino acid catabolic process |
|
227986_at |
ZNF343 |
zinc finger protein 343 |
20 |
-2410466 |
AW014719 |
79175 |
20p13 |
Hs.516846 |
4 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
241999_at |
SFXN5 |
sideroflexin 5 |
2 |
-73022672 |
AA725691 |
94097 |
|
Hs.368171 |
6 |
iron ion binding mitochondrion mitochondrial inner membrane cation transport iron ion transport cation transmembrane transporter activity membrane integral to membrane |
|
220009_at |
LONRF3 |
LON peptidase N-terminal domain and ring finger 3 |
X |
117992740 |
NM_024778 |
79836 |
Xq24 |
Hs.144266 |
6 |
ATP-dependent peptidase activity protein binding proteolysis zinc ion binding metal ion binding |
|
205749_at |
CYP1A1 |
cytochrome P450, family 1, subfamily A, polypeptide 1 |
15 |
-72798935 |
NM_000499 |
1543 |
15q24.1 |
Hs.72912 |
612 |
endoplasmic reticulum microsome electron carrier activity membrane drug metabolic process oxygen binding heme binding vitamin D metabolic process metal ion binding oxidation reduction aromatase activity vitamin D 24-hydroxylase activity |
Tryptophan metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 |
218680_x_at |
C15orf63 |
chromosome 15 open reading frame 63 |
15 |
41879912 |
NM_016400 |
25764 |
15q15.3 |
Hs.631692 |
6 |
protein binding |
|
234486_at |
-0.360 |
5.275 |
-2.566 |
2.133e-02 |
0.497 |
-3.196 |
OR51B2 |
olfactory receptor, family 51, subfamily B, member 2 |
11 |
-5301103 |
AF137396 |
79345 |
11p15 |
Hs.680163 |
4 |
receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus |
Olfactory transduction |
213778_x_at |
ZNF276 |
zinc finger protein 276 |
16 |
88314893, 88315452 |
AI983201 |
92822 |
16q24.3 |
Hs.290154 |
8 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
244477_at |
SLC12A3 |
solute carrier family 12 (sodium/chloride transporters), member 3 |
16 |
55456619 |
AW292635 |
6559 |
16q13 |
Hs.669115 |
52 |
transporter activity membrane fraction integral to plasma membrane ion transport sodium ion transport chloride transport symporter activity sodium:chloride symporter activity membrane apical plasma membrane sodium ion binding |
|
217335_at |
FLJ11292 |
hypothetical protein FLJ11292 |
5 |
|
AK023539 |
55338 |
5q14.3 |
Hs.677194 Hs.719629 |
2 |
|
|
222116_s_at |
0.367 |
5.189 |
2.339 |
3.340e-02 |
0.552 |
-3.571 |
TBC1D16 |
TBC1 domain family, member 16 |
17 |
-75528413 |
AL157485 |
125058 |
17q25.3 |
Hs.369819 |
4 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
221637_s_at |
C11orf48 |
chromosome 11 open reading frame 48 |
11 |
-62186864 |
BC001434 |
79081 |
11q12.3 |
Hs.9061 |
3 |
|
|
1554486_a_at |
-0.257 |
2.623 |
-2.550 |
2.200e-02 |
0.499 |
-3.222 |
C6orf114 |
chromosome 6 open reading frame 114 |
6 |
-13577487 |
BC009205 |
85411 |
6p23 |
Hs.674313 |
3 |
|
|
209091_s_at |
0.209 |
9.414 |
2.155 |
4.759e-02 |
0.586 |
-3.863 |
SH3GLB1 |
SH3-domain GRB2-like endophilin B1 |
1 |
86942844 |
AF263293 |
51100 |
1p22 |
Hs.136309 |
28 |
protein insertion into mitochondrial membrane during induction of apoptosis fatty acid binding protein binding nucleus cytoplasm mitochondrion mitochondrial outer membrane microsome Golgi apparatus phosphatidic acid biosynthetic process apoptosis anti-apoptosis phospholipid biosynthetic process membrane lysophosphatidic acid acyltransferase activity protein homodimerization activity protein complex 'de novo' posttranslational protein folding |
Endocytosis |
227100_at |
-0.575 |
5.464 |
-3.274 |
5.049e-03 |
0.345 |
-1.975 |
B3GALTL |
beta 1,3-galactosyltransferase-like |
13 |
30672111 |
AI569766 |
145173 |
13q12.3 |
Hs.13205 |
11 |
endoplasmic reticulum carbohydrate metabolic process fucose metabolic process membrane integral to membrane transferase activity, transferring glycosyl groups |
|
204141_at |
0.824 |
7.991 |
2.625 |
1.895e-02 |
0.488 |
-3.097 |
TUBB2A |
tubulin, beta 2A |
6 |
-3098900 |
NM_001069 |
7280 |
6p25 |
Hs.654543 |
74 |
nucleotide binding GTPase activity structural molecule activity protein binding GTP binding microtubule microtubule-based movement protein complex protein polymerization |
Gap junction Pathogenic Escherichia coli infection - EHEC |
206463_s_at |
DHRS2 |
dehydrogenase/reductase (SDR family) member 2 |
14 |
23175412 |
NM_005794 |
10202 |
14q11.2 |
Hs.272499 |
12 |
carbonyl reductase (NADPH) activity binding nucleus nuclear envelope cytoplasm C21-steroid hormone metabolic process negative regulation of cell proliferation response to toxin oxidoreductase activity myeloid dendritic cell differentiation oxidation reduction |
|
1569905_at |
HSD11B1L |
hydroxysteroid (11-beta) dehydrogenase 1-like |
19 |
5632034, 5632046, 5632051, 5632074 |
BC018336 |
374875 |
19p13.3 |
Hs.631840 |
2 |
binding extracellular region oxidoreductase activity oxidation reduction |
|
213513_x_at |
ARPC2 |
actin related protein 2/3 complex, subunit 2, 34kDa |
2 |
218790118, 218790364 |
BG034239 |
10109 |
2q36.1 |
Hs.529303 |
23 |
actin binding structural constituent of cytoskeleton protein binding cytoplasm Golgi apparatus Arp2/3 protein complex focal adhesion cell motion positive regulation of actin filament polymerization cell leading edge cell projection |
Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
212368_at |
ZNF292 |
zinc finger protein 292 |
6 |
87921987 |
AA972711 |
23036 |
6q14.3 |
Hs.485892 Hs.656621 |
7 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
225998_at |
GAB1 |
GRB2-associated binding protein 1 |
4 |
144477432 |
AK022142 |
2549 |
4q31.21 |
Hs.618456 Hs.80720 |
69 |
SH3/SH2 adaptor activity protein binding cytosol epidermal growth factor receptor signaling pathway cell proliferation insulin receptor signaling pathway |
ErbB signaling pathway Neurotrophin signaling pathway Renal cell carcinoma |
211686_s_at |
MAK16 |
MAK16 homolog (S. cerevisiae) |
8 |
33462226 |
AF251062 |
84549 |
8p12 |
Hs.583805 |
10 |
nucleus nucleolus |
|
37201_at |
ITIH4 |
inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) |
3 |
-52822045 |
D38535 |
3700 |
3p21-p14 |
Hs.709406 |
19 |
serine-type endopeptidase inhibitor activity extracellular region acute-phase response hyaluronan metabolic process |
|
231672_at |
CES4 |
carboxylesterase 4-like |
16 |
54352011 |
AV648327 |
51716 |
16q12.2 |
Hs.535486 |
2 |
carboxylesterase activity extracellular region endoplasmic reticulum anatomical structure morphogenesis |
|
207306_at |
TCF15 |
transcription factor 15 (basic helix-loop-helix) |
20 |
-532636 |
NM_004609 |
6939 |
20p13 |
Hs.437 |
4 |
somitogenesis respiratory system process transcription factor activity RNA polymerase II transcription factor activity nucleus regulation of transcription from RNA polymerase II promoter multicellular organismal development death tail morphogenesis eating behavior ear development skin development regulation of transcription paraxial mesoderm development muscle organ morphogenesis skeletal system morphogenesis neuromuscular process controlling posture |
|
232402_at |
LOC643696 |
hypothetical LOC643696 |
15 |
|
AI205683 |
643696 |
15q25.2 |
Hs.454625 Hs.513947 |
|
|
|
202842_s_at |
DNAJB9 |
DnaJ (Hsp40) homolog, subfamily B, member 9 |
7 |
107997591 |
AL080081 |
4189 |
14q24.2-q24.3 7q31 |
Hs.6790 |
16 |
nucleus nucleolus cytoplasm endoplasmic reticulum protein folding heat shock protein binding unfolded protein binding |
|
239471_at |
-0.379 |
3.369 |
-2.671 |
1.728e-02 |
0.471 |
-3.019 |
LRRC28 |
leucine rich repeat containing 28 |
15 |
97609174 |
AW409674 |
123355 |
15q26.3 |
Hs.578684 |
4 |
protein binding |
|
216178_x_at |
0.598 |
7.325 |
2.157 |
4.744e-02 |
0.585 |
-3.861 |
ITGB1 |
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
10 |
-33236244, -33229251, -33229251, -33229251 |
AA215854 |
3688 |
10p11.2 |
Hs.643813 |
512 |
G1/S transition of mitotic cell cycle in utero embryonic development cell fate specification receptor activity integrin binding focal adhesion cellular defense response cell adhesion homophilic cell adhesion leukocyte adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation integrin complex germ cell migration cell surface integral to membrane synaptosome B cell differentiation neuromuscular junction ruffle membrane cell-cell adhesion mediated by integrin sarcolemma melanosome identical protein binding interspecies interaction between organisms sarcomere organization negative regulation of cell differentiation protein heterodimerization activity regulation of cell cycle cardiac muscle cell differentiation |
Axon guidance Focal adhesion ECM-receptor interaction Cell adhesion molecules (CAMs) Leukocyte transendothelial migration Regulation of actin cytoskeleton Pathogenic Escherichia coli infection - EHEC Pathways in cancer Small cell lung cancer Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
216893_s_at |
COL4A3 |
collagen, type IV, alpha 3 (Goodpasture antigen) |
2 |
227737524 |
U02519 |
1285 |
2q36-q37 |
Hs.570065 |
77 |
integrin binding integrin binding extracellular matrix structural constituent protein binding extracellular region collagen collagen type IV induction of apoptosis activation of caspase activity cell adhesion cell surface receptor linked signal transduction sensory perception of sound blood circulation metalloendopeptidase inhibitor activity negative regulation of cell proliferation negative regulation of angiogenesis |
|
221796_at |
0.804 |
3.411 |
2.631 |
1.872e-02 |
0.487 |
-3.086 |
NTRK2 |
neurotrophic tyrosine kinase, receptor, type 2 |
9 |
86473285, 86474414, 86474445 |
AA707199 |
4915 |
9q22.1 |
Hs.494312 Hs.712776 |
111 |
nucleotide binding vasculogenesis transmembrane receptor protein tyrosine kinase activity neurotrophin receptor activity protein binding ATP binding cytosol plasma membrane integral to plasma membrane activation of adenylate cyclase activity multicellular organismal development nervous system development feeding behavior cell surface glutamate secretion postsynaptic density transferase activity regulation of metabolic process axon dendrite growth cone brain-derived neurotrophic factor receptor signaling pathway mechanoreceptor differentiation cell soma terminal button retinal rod cell development protein amino acid autophosphorylation regulation of neurotransmitter secretion brain-derived neurotrophic factor binding presynaptic active zone regulation of dendrite development positive regulation of synaptic transmission, glutamatergic excitatory synapse |
MAPK signaling pathway Neurotrophin signaling pathway |
228046_at |
ZNF827 |
zinc finger protein 827 |
4 |
-146901337 |
AA741243 |
152485 |
4q31.21-q31.22 |
Hs.133916 Hs.633543 |
7 |
DNA binding intracellular nucleus zinc ion binding regulation of transcription metal ion binding |
|
1561537_at |
-0.283 |
5.817 |
-2.581 |
2.069e-02 |
0.497 |
-3.170 |
LOC388906 |
hypothetical protein LOC388906 |
22 |
|
BC039496 |
388906 |
22q13.2 |
Hs.679422 |
1 |
|
|
217114_at |
LOC652147 |
similar to U5 snRNP-specific protein, 200 kDa |
Un |
|
Z70200 |
652147 |
|
|
|
|
|
201192_s_at |
PITPNA |
phosphatidylinositol transfer protein, alpha |
17 |
-1368032 |
NM_006224 |
5306 |
17p13.3 |
Hs.429819 |
18 |
protein binding phospholipid binding intracellular nucleus cytoplasm lipid metabolic process transport visual perception phosphatidylcholine transmembrane transporter activity phosphatidylinositol transporter activity |
|
213819_s_at |
-0.322 |
5.071 |
-3.544 |
2.889e-03 |
0.297 |
-1.500 |
FLOT1 |
flotillin 1 |
6 |
-30803489, -2144083, -1942389 |
H45696 |
10211 |
6p21.3 |
Hs.179986 |
36 |
protein binding Golgi apparatus microtubule organizing center plasma membrane integral to membrane flotillin complex centriolar satellite melanosome |
Insulin signaling pathway |
208136_s_at |
MGC3771 |
hypothetical LOC81854 |
16 |
-3100462 |
NM_030970 |
81854 |
16p13.3 |
Hs.669490 |
1 |
|
|
207848_at |
AVP |
arginine vasopressin |
20 |
-3011201 |
NM_000490 |
551 |
20p13 |
Hs.89648 |
85 |
neurohypophyseal hormone activity extracellular region soluble fraction generation of precursor metabolites and energy water transport signal transduction cell-cell signaling vasoconstriction |
|
207763_at |
S100A5 |
S100 calcium binding protein A5 |
1 |
-151776246 |
NM_002962 |
6276 |
1q21 |
Hs.2960 |
10 |
calcium ion binding |
|
1559624_at |
STK32A |
serine/threonine kinase 32A |
5 |
146594771, 146594771 |
AK094580 |
202374 |
5q32 |
Hs.585069 |
6 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity |
|
231357_at |
CLEC12B |
C-type lectin domain family 12, member B |
12 |
10054497, 10054497 |
AW003535 |
387837 |
12p13.2 |
Hs.127937 |
3 |
receptor activity binding sugar binding plasma membrane integral to membrane |
|
206030_at |
ASPA |
aspartoacylase (Canavan disease) |
17 |
3324153, 3326045 |
NM_000049 |
443 |
17pter-p13 |
Hs.171142 |
27 |
aminoacylase activity nucleus cytoplasm aspartate catabolic process metabolic process zinc ion binding hydrolase activity, acting on ester bonds aspartoacylase activity metal ion binding |
Alanine, aspartate and glutamate metabolism Histidine metabolism |
227033_at |
PDIA3 |
protein disulfide isomerase family A, member 3 |
15 |
41825881 |
AI825800 |
2923 |
15q15 |
Hs.591095 |
72 |
protein disulfide isomerase activity cysteine-type endopeptidase activity phospholipase C activity protein binding endoplasmic reticulum endoplasmic reticulum lumen protein import into nucleus protein retention in ER lumen signal transduction isomerase activity melanosome positive regulation of apoptosis cell redox homeostasis |
Antigen processing and presentation |
206735_at |
CHRNA4 |
cholinergic receptor, nicotinic, alpha 4 |
20 |
-61445108 |
NM_000744 |
1137 |
20q13.2-q13.3 |
Hs.10734 |
90 |
regulation of action potential response to hypoxia nicotinic acetylcholine-activated cation-selective channel activity ion channel activity extracellular ligand-gated ion channel activity membrane fraction plasma membrane nicotinic acetylcholine-gated receptor-channel complex DNA repair ion transport calcium ion transport response to oxidative stress signal transduction synaptic transmission, cholinergic external side of plasma membrane regulation of dopamine secretion acetylcholine receptor activity integral to membrane sensory perception of pain cell junction dendrite behavioral response to nicotine B cell activation cell soma synapse postsynaptic membrane cognition membrane depolarization regulation of inhibitory postsynaptic membrane potential |
|
1553163_at |
ADPRHL1 |
ADP-ribosylhydrolase like 1 |
13 |
-113124584, -113124260 |
NM_138430 |
113622 |
13q34 |
Hs.98669 |
4 |
magnesium ion binding ADP-ribosylarginine hydrolase activity hydrolase activity protein amino acid de-ADP-ribosylation |
|
231812_x_at |
PHAX |
phosphorylated adaptor for RNA export |
5 |
125964531 |
AK023255 |
51808 |
5q23.2 |
Hs.555731 Hs.719165 |
10 |
spliceosomal snRNP biogenesis RNA binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol snRNA export from nucleus Cajal body protein transport |
|
210658_s_at |
-0.329 |
5.965 |
-2.624 |
1.900e-02 |
0.488 |
-3.099 |
GGA2 |
golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
16 |
-23383143 |
BC000284 |
23062 |
16p12 |
Hs.460336 |
37 |
protein binding intracellular endosome trans-Golgi network intracellular protein transport membrane vesicle-mediated transport membrane coat clathrin adaptor complex ADP-ribosylation factor binding |
Lysosome |
228753_at |
0.558 |
5.109 |
2.768 |
1.422e-02 |
0.446 |
-2.854 |
LOC100128737 |
hypothetical LOC100128737 |
7 |
|
AI041217 |
100128737 |
7q22.3 |
|
|
|
|
225551_at |
C1orf71 |
chromosome 1 open reading frame 71 |
1 |
244796261, 244796261 |
AW291187 |
163882 |
1q44 |
Hs.368353 |
9 |
membrane integral to membrane protein complex |
|
1553067_a_at |
GNRHR2 |
gonadotropin-releasing hormone (type 2) receptor 2 |
1 |
-144221176 |
NM_057163 |
114814 |
1q12 |
Hs.711567 Hs.714903 |
12 |
receptor activity G-protein coupled receptor activity gonadotropin-releasing hormone receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane |
|
236042_at |
LOC100130219 |
similar to hCG2041987 |
12 |
|
AI700506 |
100130219 |
12p13.33 |
Hs.410355 |
1 |
|
|
224308_s_at |
INTS2 |
integrator complex subunit 2 |
17 |
-57297511 |
AL136800 |
57508 |
17q23.2 |
Hs.279646 |
7 |
protein binding intracellular nucleus membrane integral to membrane snRNA processing integrator complex |
|
226778_at |
C8orf42 |
chromosome 8 open reading frame 42 |
8 |
-431645 |
AI632224 |
157695 |
8p23.3 |
Hs.289293 |
1 |
|
|
226990_at |
CAPRIN1 |
cell cycle associated protein 1 |
11 |
34029805, 34029805 |
AI798775 |
4076 |
11p13 |
Hs.471818 |
10 |
protein binding cytoplasm cytosol integral to plasma membrane dendrite cell projection |
|
208480_s_at |
ABCC6 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
16 |
-16222544, -16150922 |
NM_001171 |
368 |
16p13.1 |
Hs.442182 |
70 |
nucleotide binding transporter activity ATP binding plasma membrane transport visual perception integral to membrane ATPase activity response to drug ATPase activity, coupled to transmembrane movement of substances response to stimulus |
ABC transporters |
219507_at |
RSRC1 |
arginine/serine-rich coiled-coil 1 |
3 |
159310585 |
NM_016625 |
51319 |
3q25.32 |
Hs.591283 |
5 |
alternative nuclear mRNA splicing, via spliceosome protein binding nucleus protein amino acid phosphorylation nucleocytoplasmic transport RNA splicing nuclear speck response to antibiotic |
|
1556641_at |
SLC7A14 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14 |
3 |
-171660035 |
AK094547 |
57709 |
3q26.2 |
Hs.596660 |
4 |
transport amino acid transport amino acid transmembrane transporter activity membrane integral to membrane |
|
227696_at |
EXOSC6 |
exosome component 6 |
16 |
-68841634 |
AI701408 |
118460 |
16q22.1 |
Hs.660633 Hs.719211 |
9 |
3'-5'-exoribonuclease activity exosome (RNase complex) RNA binding exonuclease activity nucleus nucleolus cytoplasm rRNA processing RNA processing hydrolase activity |
RNA degradation |
203586_s_at |
ARL4D |
ADP-ribosylation factor-like 4D |
17 |
38831878 |
NM_001661 |
379 |
17q12-q21 |
Hs.183153 Hs.709866 |
13 |
nucleotide binding GTPase activity GTP binding intracellular nucleus nucleolus small GTPase mediated signal transduction protein secretion |
|
229707_at |
ZNF606 |
zinc finger protein 606 |
19 |
-63180252 |
AI817719 |
80095 |
19q13.4 |
Hs.654967 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
229659_s_at |
PIGR |
polymeric immunoglobulin receptor |
1 |
-205168491 |
BE501712 |
5284 |
1q31-q41 |
Hs.497589 |
56 |
protein binding extracellular region plasma membrane integral to plasma membrane |
|
213727_x_at |
MPPE1 |
metallophosphoesterase 1 |
18 |
-11873471 |
AI743654 |
65258 |
18p11.21 |
Hs.712666 |
8 |
membrane integral to membrane hydrolase activity metal ion binding |
|
244264_at |
KLRG2 |
killer cell lectin-like receptor subfamily G, member 2 |
7 |
-138788627 |
AW197495 |
346689 |
7q34 |
Hs.17572 |
2 |
binding sugar binding membrane integral to membrane |
|
236087_at |
0.306 |
6.534 |
2.509 |
2.390e-02 |
0.509 |
-3.292 |
ABLIM2 |
actin binding LIM protein family, member 2 |
4 |
-8059647, -8017936 |
AI912773 |
84448 |
4p16.1 |
Hs.233404 |
9 |
actin binding cytoplasm cytoskeleton organization zinc ion binding actin cytoskeleton myofibril positive regulation of transcription from RNA polymerase II promoter metal ion binding |
Axon guidance |
235977_at |
LONRF2 |
LON peptidase N-terminal domain and ring finger 2 |
2 |
-100256184 |
BF433341 |
164832 |
2q11.2 |
Hs.21380 |
4 |
ATP-dependent peptidase activity protein binding proteolysis zinc ion binding metal ion binding |
|
1553207_at |
ARL10 |
ADP-ribosylation factor-like 10 |
5 |
175725107 |
NM_173664 |
285598 |
5q35.2 |
Hs.424552 |
3 |
nucleotide binding GTP binding |
|
224663_s_at |
CFL2 |
cofilin 2 (muscle) |
14 |
-34249338, -34249338, -34249338 |
BF576053 |
1073 |
14q12 |
Hs.180141 |
20 |
actin binding protein binding intracellular nucleus cytoplasm cytoskeleton nuclear matrix |
Axon guidance Fc gamma R-mediated phagocytosis Regulation of actin cytoskeleton |
212752_at |
CLASP1 |
cytoplasmic linker associated protein 1 |
2 |
-121811823 |
AA176798 |
23332 |
2q14.2-q14.3 |
Hs.469840 Hs.708183 |
21 |
condensed chromosome kinetochore microtubule bundle formation protein binding cytoplasm Golgi apparatus kinetochore microtubule cytoskeleton cytoplasmic microtubule cell cortex negative regulation of microtubule depolymerization negative regulation of microtubule depolymerization cell cycle mitosis establishment or maintenance of cell polarity exit from mitosis cortical microtubule cytoskeleton centrosomal corona kinetochore binding microtubule plus-end binding cell division |
|
1567064_at |
OR1Q1 |
olfactory receptor, family 1, subfamily Q, member 1 |
9 |
124416837 |
X89667 |
158131 |
9q33.2 |
Hs.684864 |
3 |
receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus |
Olfactory transduction |
202754_at |
R3HDM1 |
R3H domain containing 1 |
2 |
136005552 |
NM_015361 |
23518 |
2q21.3 |
Hs.412462 |
8 |
nucleic acid binding |
|
207628_s_at |
WBSCR22 |
Williams Beuren syndrome chromosome region 22 |
7 |
72735833 |
NM_017528 |
114049 |
|
Hs.647063 |
9 |
cellular_component nucleus metabolic process methyltransferase activity transferase activity |
Androgen and estrogen metabolism Histidine metabolism Tyrosine metabolism Aminophosphonate metabolism Selenoamino acid metabolism |
1561423_at |
LOC642924 |
hypothetical protein LOC642924 |
8 |
|
BC037909 |
642924 |
8q22.1 |
Hs.434882 |
1 |
|
|
225605_at |
TP53I13 |
tumor protein p53 inducible protein 13 |
17 |
24919864 |
AL540867 |
90313 |
17q11.2 |
Hs.514050 |
4 |
cytoplasm plasma membrane integral to membrane |
|
202213_s_at |
CUL4B |
cullin 4B |
X |
-119542473, -119542473 |
AI650819 |
8450 |
Xq23 |
Hs.102914 |
28 |
molecular_function protein binding cellular_component DNA repair ubiquitin-dependent protein catabolic process response to DNA damage stimulus cell cycle cullin-RING ubiquitin ligase complex ubiquitin protein ligase binding |
Nucleotide excision repair Ubiquitin mediated proteolysis |
230081_at |
PLCXD3 |
phosphatidylinositol-specific phospholipase C, X domain containing 3 |
5 |
-41342804 |
AI694325 |
345557 |
5p13.1 |
Hs.145404 |
|
phospholipase C activity signal transducer activity intracellular signaling cascade lipid catabolic process hydrolase activity |
|
211376_s_at |
0.184 |
6.571 |
2.224 |
4.173e-02 |
0.574 |
-3.755 |
NSMCE4A |
non-SMC element 4 homolog A (S. cerevisiae) |
10 |
-123706592 |
BC005212 |
54780 |
10q26.13 |
Hs.258798 |
8 |
|
|
226264_at |
SUSD1 |
sushi domain containing 1 |
9 |
-113842881 |
AL137432 |
64420 |
9q31.3-q33.1 |
Hs.494827 |
8 |
calcium ion binding membrane integral to membrane |
|
218856_at |
0.692 |
5.906 |
4.189 |
7.675e-04 |
0.211 |
-0.377 |
TNFRSF21 |
tumor necrosis factor receptor superfamily, member 21 |
6 |
-47307226 |
NM_016629 |
27242 |
6p21.1-p12.2 |
Hs.443577 |
15 |
receptor activity protein binding apoptosis signal transduction membrane integral to membrane |
Cytokine-cytokine receptor interaction |
209198_s_at |
SYT11 |
synaptotagmin XI |
1 |
154095913 |
BC004291 |
23208 |
1q21.2 |
Hs.32984 |
14 |
transporter activity calcium ion binding protein binding calcium-dependent phospholipid binding integral to plasma membrane transport synaptic vesicle membrane cell junction cytoplasmic vesicle synapse |
|
210544_s_at |
0.795 |
6.810 |
4.706 |
2.713e-04 |
0.175 |
0.492 |
ALDH3A2 |
aldehyde dehydrogenase 3 family, member A2 |
17 |
19492655, 19492655 |
BC002430 |
224 |
17p11.2 |
Hs.499886 |
27 |
3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD) activity aldehyde dehydrogenase [NAD(P)+] activity mitochondrial inner membrane endoplasmic reticulum cellular aldehyde metabolic process lipid metabolic process central nervous system development peripheral nervous system development epidermis development membrane integral to membrane oxidoreductase activity oxidation reduction |
Glycolysis / Gluconeogenesis Ascorbate and aldarate metabolism Fatty acid metabolism Valine, leucine and isoleucine degradation Lysine degradation Arginine and proline metabolism Histidine metabolism Tryptophan metabolism beta-Alanine metabolism Glycerolipid metabolism Pyruvate metabolism Propanoate metabolism 3-Chloroacrylic acid degradation Butanoate metabolism Limonene and pinene degradation Metabolic pathways |
209727_at |
GM2A |
GM2 ganglioside activator |
5 |
150612805 |
M76477 |
2760 |
5q31.3-q33.1 |
Hs.483873 |
32 |
lipid transporter activity cytoplasm mitochondrion lysosome hydrogen:potassium-exchanging ATPase complex lipid metabolic process ganglioside catabolic process lipid transport learning or memory oligosaccharide catabolic process internal side of plasma membrane phospholipase activator activity glycolipid catabolic process lipid storage sphingolipid catabolic process sphingolipid activator protein activity beta-N-acetylgalactosaminidase activity apical cortex neurological system process neuromuscular process controlling balance positive regulation of hydrolase activity |
Lysosome |
226934_at |
CPSF6 |
cleavage and polyadenylation specific factor 6, 68kDa |
12 |
67919583 |
AU149663 |
11052 |
12q15 |
Hs.369606 |
19 |
nucleotide binding RNA binding protein binding nucleus mRNA cleavage factor complex mRNA processing ribonucleoprotein complex paraspeckles |
|
1558747_at |
SMCHD1 |
structural maintenance of chromosomes flexible hinge domain containing 1 |
18 |
2645885 |
AA336502 |
23347 |
18p11.32 |
Hs.8118 |
6 |
protein binding ATP binding chromosome chromosome organization |
|
222665_at |
0.286 |
7.251 |
2.576 |
2.090e-02 |
0.497 |
-3.179 |
FAM82B |
family with sequence similarity 82, member B |
8 |
-87553693 |
AK000672 |
51115 |
8q21.3 |
Hs.145386 |
5 |
binding cytoplasm microtubule |
|
202399_s_at |
0.462 |
8.150 |
3.615 |
2.497e-03 |
0.287 |
-1.376 |
AP3S2 |
adaptor-related protein complex 3, sigma 2 subunit |
15 |
-88174834 |
NM_005829 |
10239 |
15q26.1 |
Hs.632161 |
14 |
protein binding Golgi apparatus intracellular protein transport protein transporter activity membrane vesicle-mediated transport membrane coat cytoplasmic vesicle |
Lysosome |
205164_at |
GCAT |
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) |
22 |
36533900 |
NM_014291 |
23464 |
22q13.1 |
Hs.54609 |
6 |
mitochondrion mitochondrial inner membrane cellular amino acid metabolic process acyltransferase activity glycine C-acetyltransferase activity biosynthetic process transferase activity, transferring nitrogenous groups pyridoxal phosphate binding |
Glycine, serine and threonine metabolism |
221211_s_at |
C21orf7 |
chromosome 21 open reading frame 7 |
21 |
29374743 |
NM_020152 |
56911 |
21q22.3 |
Hs.222802 |
13 |
protein binding nucleus cytosol |
|
226727_at |
CISD3 |
CDGSH iron sulfur domain 3 |
17 |
34140035 |
BG171264 |
284106 |
17q12 |
Hs.713595 |
4 |
iron ion binding mitochondrion metal ion binding 2 iron, 2 sulfur cluster binding |
|
218909_at |
RPS6KC1 |
ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
1 |
211291210 |
NM_012424 |
26750 |
1q41 |
Hs.591416 |
10 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding cytoplasm early endosome protein amino acid phosphorylation signal transduction membrane transferase activity phosphoinositide binding |
|
201927_s_at |
PKP4 |
plakophilin 4 |
2 |
159021721 |
BG292559 |
8502 |
2q23-q31 |
Hs.407580 |
27 |
protein binding cell adhesion desmosome |
|
212858_at |
PAQR4 |
progestin and adipoQ receptor family member IV |
16 |
2959342 |
AL520675 |
124222 |
16p13.3 |
Hs.351474 |
5 |
receptor activity membrane integral to membrane |
|
209999_x_at |
SOCS1 |
suppressor of cytokine signaling 1 |
16 |
-11255774 |
AI056051 |
8651 |
16p13.13 |
Hs.50640 |
122 |
regulation of protein amino acid phosphorylation protein kinase inhibitor activity insulin-like growth factor receptor binding protein binding cytoplasm intracellular signaling cascade cytokine-mediated signaling pathway protein kinase binding modification-dependent protein catabolic process regulation of growth negative regulation of tyrosine phosphorylation of Stat3 protein fat cell differentiation negative regulation of JAK-STAT cascade negative regulation of JAK-STAT cascade negative regulation of insulin receptor signaling pathway |
Ubiquitin mediated proteolysis Jak-STAT signaling pathway Insulin signaling pathway Type II diabetes mellitus |
220794_at |
GREM2 |
gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) |
1 |
-238719495 |
NM_022469 |
64388 |
1q43 |
Hs.98206 |
9 |
cytokine activity extracellular region extracellular region extracellular space BMP signaling pathway |
|
204186_s_at |
PPID |
peptidylprolyl isomerase D |
4 |
-159849728 |
AI014573 |
5481 |
4q31.3 |
Hs.581725 |
25 |
peptidyl-prolyl cis-trans isomerase activity cytoplasm protein folding cyclosporin A binding isomerase activity heat shock protein binding |
Calcium signaling pathway Parkinson's disease Huntington's disease |
200976_s_at |
0.348 |
9.179 |
2.494 |
2.460e-02 |
0.513 |
-3.316 |
TAX1BP1 |
Tax1 (human T-cell leukemia virus type I) binding protein 1 |
7 |
27746262 |
NM_006024 |
8887 |
7p15 |
Hs.34576 |
21 |
intracellular apoptosis anti-apoptosis zinc ion binding identical protein binding |
|
224385_s_at |
MOV10L1 |
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) |
22 |
48870561, 48870811, 48927610 |
AF285604 |
54456 |
22q13.33 |
Hs.62880 |
7 |
nucleotide binding magnesium ion binding RNA binding ATP-dependent RNA helicase activity helicase activity ATP binding intracellular multicellular organismal development germ cell development spermatogenesis muscle organ development cell proliferation hydrolase activity negative regulation of cell cycle |
|
226735_at |
TAPT1 |
transmembrane anterior posterior transformation 1 |
4 |
-15771225 |
AI239899 |
202018 |
4p15.32 |
Hs.479223 |
5 |
receptor activity multicellular organismal development membrane integral to membrane |
|
203459_s_at |
VPS16 |
vacuolar protein sorting 16 homolog (S. cerevisiae) |
20 |
2769372, 2792592 |
NM_022575 |
64601 |
20p13-p12 |
Hs.269577 |
6 |
cytoplasm lysosome endosome intracellular protein transport membrane |
|
227825_at |
NAIF1 |
nuclear apoptosis inducing factor 1 |
9 |
-129863332 |
BE293321 |
203245 |
9q34.11 |
Hs.373606 |
8 |
molecular_function nucleus apoptosis induction of apoptosis |
|
210602_s_at |
CDH6 |
cadherin 6, type 2, K-cadherin (fetal kidney) |
5 |
31229552 |
BC000019 |
1004 |
5p15.1-p14 |
Hs.171054 |
14 |
calcium ion binding protein binding nucleus cytoplasm plasma membrane cell adhesion homophilic cell adhesion female gonad development integral to membrane |
|
228017_s_at |
NKAIN4 |
Na+/K+ transporting ATPase interacting 4 |
20 |
-61342581 |
BF593263 |
128414 |
20q13.33 |
Hs.46627 |
7 |
plasma membrane integral to membrane |
|
220092_s_at |
ANTXR1 |
anthrax toxin receptor 1 |
2 |
69093779, 69093779, 69093779 |
NM_018153 |
84168 |
2p13.1 |
Hs.165859 |
24 |
transmembrane receptor activity collagen binding membrane integral to membrane lamellipodium membrane filopodium membrane actin cytoskeleton reorganization substrate adhesion-dependent cell spreading metal ion binding actin filament binding |
|
217884_at |
NAT10 |
N-acetyltransferase 10 (GCN5-related) |
11 |
34083686 |
NM_024662 |
55226 |
11p13 |
Hs.577281 |
18 |
nucleotide binding molecular_function protein binding ATP binding nucleus nucleolus N-acetyltransferase activity metabolic process acyltransferase activity transferase activity |
|
223925_s_at |
LUZP6 |
leucine zipper protein 6 |
7 |
-135262042 |
AF130088 |
767558 |
7q33 |
Hs.654894 |
2 |
|
|
201932_at |
0.213 |
7.023 |
2.288 |
3.685e-02 |
0.561 |
-3.652 |
LRRC41 |
leucine rich repeat containing 41 |
1 |
-46516658 |
NM_006369 |
10489 |
1p34.1 |
Hs.144941 |
12 |
modification-dependent protein catabolic process |
|
227956_at |
ITPRIPL2 |
inositol 1,4,5-triphosphate receptor interacting protein-like 2 |
16 |
19032754 |
AI458417 |
162073 |
16p12.3 |
Hs.530899 Hs.648523 |
3 |
membrane integral to membrane |
|
1552293_at |
TMEM196 |
transmembrane protein 196 |
7 |
-19725463 |
NM_152774 |
256130 |
7p21.1 |
Hs.487670 |
1 |
membrane integral to membrane |
|
238448_at |
0.316 |
2.945 |
2.894 |
1.101e-02 |
0.424 |
-2.637 |
MRPL19 |
mitochondrial ribosomal protein L19 |
2 |
75727416 |
BE544070 |
9801 |
2q11.1-q11.2 |
Hs.44024 |
11 |
structural constituent of ribosome intracellular nucleus mitochondrion ribosome translation nuclear membrane |
|
224777_s_at |
PAFAH1B2 |
platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa) |
11 |
116520249 |
BG386322 |
5049 |
11q23 |
Hs.718419 |
15 |
1-alkyl-2-acetylglycerophosphocholine esterase activity protein binding cytoplasm spermatogenesis lipid catabolic process hydrolase activity, acting on ester bonds |
Ether lipid metabolism Metabolic pathways |
208670_s_at |
EID1 |
EP300 interacting inhibitor of differentiation 1 |
15 |
46957581 |
AF274951 |
23741 |
15q21.1-q21.2 |
Hs.255973 Hs.714048 |
12 |
negative regulation of transcription from RNA polymerase II promoter transcription corepressor activity protein binding cellular_component nucleus cytoplasm cell cycle specific transcriptional repressor activity cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of transcription |
|
207216_at |
TNFSF8 |
tumor necrosis factor (ligand) superfamily, member 8 |
9 |
-116704944 |
NM_001244 |
944 |
9q33 |
Hs.654445 |
19 |
cytokine activity tumor necrosis factor receptor binding extracellular space integral to plasma membrane induction of apoptosis immune response signal transduction cell-cell signaling cell proliferation membrane |
Cytokine-cytokine receptor interaction |
229547_s_at |
WNK2 |
WNK lysine deficient protein kinase 2 |
9 |
94987032 |
AI832477 |
65268 |
9q22.3 |
Hs.654856 |
13 |
nucleotide binding protein serine/threonine kinase activity protein binding ATP binding protein amino acid phosphorylation protein kinase cascade transferase activity |
|
1563252_at |
ERBB3 |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
12 |
54760158, 54760158 |
U88360 |
2065 |
12q13 |
Hs.118681 |
136 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity transmembrane receptor activity ATP binding extracellular region extracellular space plasma membrane integral to plasma membrane protein amino acid phosphorylation negative regulation of cell adhesion transmembrane receptor protein tyrosine kinase signaling pathway heart development negative regulation of signal transduction Schwann cell differentiation positive regulation of phosphoinositide 3-kinase cascade basolateral plasma membrane apical plasma membrane lateral plasma membrane transferase activity growth factor binding growth factor binding cranial nerve development protein tyrosine kinase activator activity wound healing regulation of cell proliferation protein homodimerization activity receptor complex negative regulation of neuron apoptosis protein heterodimerization activity negative regulation of secretion |
ErbB signaling pathway Calcium signaling pathway Endocytosis |
217565_at |
GRIA3 |
glutamate receptor, ionotrophic, AMPA 3 |
X |
122145776 |
BF110551 |
2892 |
Xq25-q26 |
Hs.377070 |
34 |
receptor activity ionotropic glutamate receptor activity ion channel activity extracellular-glutamate-gated ion channel activity plasma membrane ion transport glutamate signaling pathway integral to membrane cell junction synapse postsynaptic membrane |
Neuroactive ligand-receptor interaction Long-term depression |
223436_s_at |
0.614 |
8.773 |
2.195 |
4.412e-02 |
0.579 |
-3.801 |
TRPT1 |
tRNA phosphotransferase 1 |
11 |
-63747847, -63747847 |
BC005133 |
83707 |
11q13.1 |
Hs.326586 |
6 |
tRNA 2'-phosphotransferase activity tRNA splicing, via endonucleolytic cleavage and ligation transferase activity, transferring phosphorus-containing groups |
|
212204_at |
TMEM87A |
transmembrane protein 87A |
15 |
-40337427, -40290017 |
AL049944 |
25963 |
15q15.1 |
Hs.511138 Hs.719196 |
6 |
membrane integral to membrane |
|
217814_at |
CCDC47 |
coiled-coil domain containing 47 |
17 |
-59176341 |
NM_020198 |
57003 |
17q23.3 |
Hs.202011 |
9 |
protein binding cellular_component biological_process membrane integral to membrane |
|
218042_at |
COPS4 |
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) |
4 |
84175262 |
NM_016129 |
51138 |
4q21.22 |
Hs.190384 |
22 |
protein binding nucleus cytoplasm signalosome |
|
218582_at |
0.540 |
7.441 |
2.703 |
1.620e-02 |
0.461 |
-2.964 |
MARCH5 |
membrane-associated ring finger (C3HC4) 5 |
10 |
94040899 |
NM_017824 |
54708 |
10q23.32-q23.33 |
Hs.573490 |
8 |
mitochondrion mitochondrial outer membrane zinc ion binding membrane integral to membrane ligase activity modification-dependent protein catabolic process metal ion binding |
|
235551_at |
WDR4 |
WD repeat domain 4 |
21 |
-43142404, -43136272 |
AA555280 |
10785 |
21q22.3 |
Hs.248815 |
10 |
protein binding nucleus nucleoplasm cytoplasm tRNA modification tRNA (guanine-N7-)-methyltransferase activity |
|
1557217_a_at |
FANCB |
Fanconi anemia, complementation group B |
X |
-14771449 |
BC043596 |
2187 |
Xp22.2 |
Hs.554740 |
16 |
nucleus DNA repair response to DNA damage stimulus |
|
233905_at |
SPAG4L |
sperm associated antigen 4-like |
20 |
-31035241 |
AL139826 |
140732 |
20q11.21 |
Hs.375186 |
8 |
molecular_function cellular_component spermatogenesis |
|
223144_s_at |
AKIRIN2 |
akirin 2 |
6 |
-88441298 |
BC000764 |
55122 |
6q15 |
Hs.485915 |
10 |
protein binding nucleus embryonic development transcriptional repressor complex response to lipopolysaccharide positive regulation of interleukin-6 production innate immune response regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
|
214165_s_at |
HS6ST1 |
heparan sulfate 6-O-sulfotransferase 1 |
2 |
-128739523 |
BF512553 |
9394 |
2q21 |
Hs.512841 |
6 |
angiogenesis placenta development integral to plasma membrane sulfotransferase activity heparan sulfate proteoglycan biosynthetic process, enzymatic modification membrane transferase activity lung alveolus development |
Heparan sulfate biosynthesis |
220130_x_at |
LTB4R2 |
leukotriene B4 receptor 2 |
14 |
23848000 |
NM_019839 |
56413 |
14q11.2-q12 |
Hs.642693 Hs.657595 Hs.711130 |
22 |
leukotriene B4 receptor activity receptor activity membrane fraction plasma membrane integral to plasma membrane chemotaxis signal transduction G-protein coupled receptor protein signaling pathway negative regulation of adenylate cyclase activity keratinocyte migration |
Calcium signaling pathway Neuroactive ligand-receptor interaction |
216696_s_at |
PRODH2 |
proline dehydrogenase (oxidase) 2 |
19 |
-40982731 |
U95090 |
58510 |
19q13.1 |
Hs.515366 |
2 |
proline dehydrogenase activity mitochondrial inner membrane glutamate biosynthetic process proline catabolic process oxidoreductase activity oxidation reduction |
Arginine and proline metabolism Metabolic pathways |
221276_s_at |
SYNC |
syncoilin, intermediate filament protein |
1 |
-32918093 |
NM_030786 |
81493 |
1p34.3-p33 |
Hs.712631 |
6 |
structural molecule activity protein binding cytoplasm cytosol intermediate filament Z disc sarcolemma intermediate filament-based process synapse perinuclear region of cytoplasm |
|
208933_s_at |
0.453 |
5.692 |
3.953 |
1.244e-03 |
0.236 |
-0.785 |
LGALS8 |
lectin, galactoside-binding, soluble, 8 |
1 |
234748187, 234753361, 234753699 |
AI659005 |
3964 |
1q42-q43 |
Hs.4082 Hs.708114 |
29 |
sugar binding extracellular space cytoplasm |
|
220674_at |
CD22 |
CD22 molecule |
19 |
40511918 |
NM_024916 |
933 |
19q13.1 |
Hs.579691 |
46 |
protein binding sugar binding plasma membrane cell adhesion integral to membrane |
Cell adhesion molecules (CAMs) Hematopoietic cell lineage B cell receptor signaling pathway |
225540_at |
0.390 |
4.931 |
2.336 |
3.357e-02 |
0.552 |
-3.575 |
MAP2 |
microtubule-associated protein 2 |
2 |
209997015, 210152647 |
BF342661 |
4133 |
2q34-q35 |
Hs.368281 |
58 |
structural molecule activity calmodulin binding cytoplasm cytoskeleton microtubule microtubule associated complex negative regulation of microtubule depolymerization |
|
202271_at |
FBXO28 |
F-box protein 28 |
1 |
222368413 |
AB007952 |
23219 |
1q42.11 |
Hs.64691 Hs.713992 |
10 |
modification-dependent protein catabolic process |
|
233048_at |
FAM35A |
family with sequence similarity 35, member A |
10 |
88844932 |
AK025471 |
54537 |
10q23.2 |
Hs.500419 |
6 |
|
|
207608_x_at |
-0.402 |
6.600 |
-2.352 |
3.252e-02 |
0.548 |
-3.549 |
CYP1A2 |
cytochrome P450, family 1, subfamily A, polypeptide 2 |
15 |
72828236 |
NM_000761 |
1544 |
15q24.1 |
Hs.1361 |
233 |
endoplasmic reticulum endoplasmic reticulum membrane microsome cellular aromatic compound metabolic process porphyrin metabolic process electron carrier activity toxin metabolic process post-embryonic development regulation of gene expression membrane drug metabolic process dibenzo-p-dioxin metabolic process oxygen binding heme binding lung development demethylase activity cellular respiration metal ion binding hydrogen peroxide biosynthetic process oxidation reduction aromatase activity |
Caffeine metabolism Tryptophan metabolism Linoleic acid metabolism Retinol metabolism Metabolism of xenobiotics by cytochrome P450 Drug metabolism - cytochrome P450 Metabolic pathways |
205747_at |
CBLN1 |
cerebellin 1 precursor |
16 |
-47869711 |
NM_004352 |
869 |
16q12.1 |
Hs.458423 |
8 |
protein binding extracellular region synaptic transmission nervous system development membrane cell junction protein homodimerization activity synapse |
|
215011_at |
SNHG3 |
small nucleolar RNA host gene 3 (non-protein coding) |
1 |
28705082 |
AJ006835 |
8420 |
1p36.1 |
Hs.469723 |
5 |
|
|
1567068_at |
OR4D1 |
olfactory receptor, family 4, subfamily D, member 1 |
17 |
53587513 |
X89670 |
26689 |
17q23.2 |
Hs.531188 |
3 |
receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus |
Olfactory transduction |
243301_at |
COL22A1 |
collagen, type XXII, alpha 1 |
8 |
-139669659 |
AW241910 |
169044 |
8q24.23-q24.3 |
Hs.117169 |
2 |
|
|
220395_at |
DNAJA4 |
DnaJ (Hsp40) homolog, subfamily A, member 4 |
15 |
76343541, 76344043, 76345614 |
NM_018602 |
55466 |
15q25.1 |
Hs.513053 |
5 |
protein folding zinc ion binding membrane heat shock protein binding metal ion binding unfolded protein binding |
|
218079_s_at |
GGNBP2 |
gametogenetin binding protein 2 |
17 |
31974916 |
NM_024835 |
79893 |
17q12 |
Hs.514116 |
4 |
multicellular organismal development spermatogenesis cell differentiation cytoplasmic vesicle |
|
221634_at |
RPL23AP7 |
ribosomal protein L23a pseudogene 7 |
2 |
-114095774, -114085285 |
BC000596 |
118433 |
2q14 |
Hs.541177 Hs.595056 |
6 |
|
|
209762_x_at |
SP110 |
SP110 nuclear body protein |
2 |
-230749432, -230741889 |
AF280094 |
3431 |
2q37.1 |
Hs.145150 |
20 |
DNA binding hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity protein binding nucleus zinc ion binding interspecies interaction between organisms regulation of transcription metal ion binding |
|
AFFX-HUMISGF3A/M97935_MA_at |
-0.196 |
5.781 |
-2.162 |
4.692e-02 |
0.583 |
-3.852 |
STAT1 |
signal transducer and activator of transcription 1, 91kDa |
2 |
-191548507, -191542006 |
AFFX-HUMISGF3A/M97935_MA |
6772 |
2q32.2 |
Hs.642990 Hs.715518 |
323 |
transcription factor activity signal transducer activity hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity calcium ion binding protein binding nucleus nucleolus cytoplasm regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter activation of caspase activity signal transduction I-kappaB kinase/NF-kappaB cascade tyrosine phosphorylation of STAT protein response to virus interspecies interaction between organisms |
Chemokine signaling pathway Toll-like receptor signaling pathway Jak-STAT signaling pathway Pathways in cancer Pancreatic cancer |
212721_at |
SFRS12 |
splicing factor, arginine/serine-rich 12 |
5 |
65475840, 65476418 |
AI810380 |
140890 |
5q12.3 |
Hs.519347 |
12 |
nucleotide binding nucleic acid binding protein binding nucleus spliceosomal complex mRNA processing RNA splicing |
|
205526_s_at |
KATNA1 |
katanin p60 (ATPase-containing) subunit A 1 |
6 |
-149957864 |
NM_007044 |
11104 |
6q25.1 |
Hs.450175 |
12 |
nucleotide binding spindle pole ATP binding cytoplasm centrosome microtubule cell cycle mitosis microtubule binding microtubule-severing ATPase activity hydrolase activity nucleoside-triphosphatase activity protein heterodimerization activity cell division interphase of mitotic cell cycle |
|
231784_s_at |
DCAF13 |
DDB1 and CUL4 associated factor 13 |
8 |
104496117 |
AK001874 |
25879 |
8q22.3 |
Hs.532265 |
4 |
nucleus nucleolus rRNA processing ribonucleoprotein complex |
|
222318_at |
ZNF324B |
zinc finger protein 324B |
19 |
63654782 |
AI744673 |
388569 |
19q13.43 |
Hs.186970 |
3 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
236834_at |
SCFD2 |
sec1 family domain containing 2 |
4 |
-53433907 |
AI025103 |
152579 |
4q12 |
Hs.302287 |
3 |
vesicle docking during exocytosis protein transport vesicle-mediated transport |
|
213115_at |
ATG4A |
ATG4 autophagy related 4 homolog A (S. cerevisiae) |
X |
107221589 |
AL031177 |
115201 |
Xq22.1-q22.3 |
Hs.8763 |
8 |
cytoplasm microtubule associated complex proteolysis protein targeting to vacuole autophagy microtubule binding peptidase activity cysteine-type peptidase activity protein transport modification-dependent protein catabolic process |
Regulation of autophagy |
212735_at |
KIAA0226 |
KIAA0226 |
3 |
-198882710, -198882655 |
BF448041 |
9711 |
3q29 |
Hs.478868 |
6 |
|
|
227088_at |
PDE5A |
phosphodiesterase 5A, cGMP-specific |
4 |
-120634997, -120634997, -120634997 |
BF221547 |
8654 |
4q25-q27 |
Hs.587281 Hs.647971 |
43 |
nucleotide binding magnesium ion binding cellular_component signal transduction zinc ion binding cyclic nucleotide metabolic process hydrolase activity cGMP binding 3',5'-cyclic-GMP phosphodiesterase activity |
Purine metabolism |
215463_at |
-0.353 |
4.096 |
-2.380 |
3.084e-02 |
0.542 |
-3.504 |
OR7E24 |
olfactory receptor, family 7, subfamily E, member 24 |
19 |
9222719 |
BF062364 |
26648 |
19p13.2 |
Hs.129832 |
5 |
receptor activity olfactory receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway sensory perception of smell integral to membrane response to stimulus |
Olfactory transduction |
204450_x_at |
APOA1 |
apolipoprotein A-I |
11 |
-116211678, 13497 |
NM_000039 |
335 |
11q23-q24 |
Hs.633003 |
424 |
beta-amyloid binding negative regulation of cytokine secretion during immune response phospholipid binding extracellular region extracellular region endoplasmic reticulum lumen lipid metabolic process phosphatidylcholine biosynthetic process lipid transport G-protein coupled receptor protein signaling pathway steroid metabolic process cholesterol metabolic process positive regulation of cholesterol esterification negative regulation of very-low-density lipoprotein particle remodeling cholesterol binding cholesterol transporter activity cholesterol transporter activity enzyme binding endocytic vesicle cytoplasmic vesicle Cdc42 protein signal transduction cholesterol efflux phospholipid efflux apolipoprotein A-I receptor binding very-low-density lipoprotein particle spherical high-density lipoprotein particle high-density lipoprotein particle assembly high-density lipoprotein particle clearance lipoprotein metabolic process cholesterol homeostasis identical protein binding reverse cholesterol transport negative regulation of interleukin-1 beta secretion protein stabilization positive regulation of hydrolase activity phosphatidylcholine-sterol O-acyltransferase activator activity cholesterol import high-density lipoprotein receptor binding |
PPAR signaling pathway |
235472_at |
FUT10 |
fucosyltransferase 10 (alpha (1,3) fucosyltransferase) |
8 |
-33347885 |
AI147738 |
84750 |
8p12 |
Hs.458713 |
5 |
Golgi membrane Golgi apparatus protein folding protein amino acid glycosylation protein targeting nervous system development fertilization embryonic development membrane integral to membrane transferase activity, transferring glycosyl groups hemopoiesis wound healing L-fucose catabolic process alpha(1,3)-fucosyltransferase activity |
|
227733_at |
TMEM63C |
transmembrane protein 63C |
14 |
76717854 |
AA928939 |
57156 |
14q24.3 |
Hs.22452 |
3 |
membrane integral to membrane |
|
219816_s_at |
RBM23 |
RNA binding motif protein 23 |
14 |
-22439693 |
NM_018107 |
55147 |
14q11.2 |
Hs.4997 |
11 |
nucleotide binding RNA binding nucleus nucleolus mRNA processing |
|
217066_s_at |
DMPK |
dystrophia myotonica-protein kinase |
19 |
-50964815, -50964815 |
M87313 |
1760 |
19q13.3 |
Hs.631596 |
91 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity protein binding ATP binding protein modification process protein amino acid phosphorylation regulation of heart contraction transferase activity |
|
1562443_at |
RLBP1L2 |
retinaldehyde binding protein 1-like 2 |
6 |
123359280 |
AK095527 |
134829 |
6q22.31 |
Hs.486361 |
2 |
transporter activity intracellular transport |
|
226106_at |
RNF141 |
ring finger protein 141 |
11 |
-10489800 |
AI307808 |
50862 |
11p15.4 |
Hs.44685 |
7 |
DNA binding protein binding regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
222621_at |
DNAJC1 |
DnaJ (Hsp40) homolog, subfamily C, member 1 |
10 |
-22085482 |
BF591419 |
64215 |
10p12.31 |
Hs.499000 |
8 |
ATPase activator activity DNA binding nucleus endoplasmic reticulum microsome regulation of translation protein folding membrane integral to membrane heat shock protein binding negative regulation of proteolysis regulation of protein secretion unfolded protein binding chaperone binding |
|
1555981_at |
C17orf65 |
chromosome 17 open reading frame 65 |
17 |
-39608877 |
AK055685 |
339201 |
17q21.31 |
Hs.656564 |
2 |
|
|
224299_x_at |
FTCD |
formiminotransferase cyclodeaminase |
21 |
-46381121, -46380603 |
AF289023 |
10841 |
21q22.3 |
Hs.415846 |
11 |
folic acid binding cytoplasm Golgi apparatus histidine metabolic process folic acid and derivative metabolic process transferase activity lyase activity glutamate formimidoyltransferase activity formimidoyltetrahydrofolate cyclodeaminase activity cellular metabolic process |
Histidine metabolism One carbon pool by folate Metabolic pathways |
206570_s_at |
PSG11 |
pregnancy specific beta-1-glycoprotein 11 |
19 |
-48203648 |
NM_002785 |
5680 |
19q13.2 |
Hs.646353 |
6 |
extracellular region female pregnancy |
|
226489_at |
TMCC3 |
transmembrane and coiled-coil domain family 3 |
12 |
-93485030 |
BG177562 |
57458 |
12q22 |
Hs.370410 |
5 |
membrane integral to membrane |
|
1557123_a_at |
-0.206 |
4.982 |
-2.146 |
4.842e-02 |
0.589 |
-3.877 |
CHADL |
chondroadherin-like |
22 |
-39955459 |
BC040188 |
150356 |
22q13.2 |
Hs.344488 Hs.714982 |
2 |
protein binding extracellular region proteinaceous extracellular matrix |
|
229229_at |
AGXT2 |
alanine-glyoxylate aminotransferase 2 |
5 |
-35033962 |
AJ292204 |
64902 |
5p13 |
Hs.34494 |
7 |
mitochondrion alanine-glyoxylate transaminase activity transferase activity pyridoxal phosphate binding (R)-3-amino-2-methylpropionate-pyruvate transaminase activity |
Alanine, aspartate and glutamate metabolism |
222429_at |
0.291 |
5.674 |
2.728 |
1.542e-02 |
0.458 |
-2.923 |
DBNL |
drebrin-like |
7 |
44050763 |
AF077353 |
28988 |
7p13 |
Hs.436500 |
26 |
ruffle intracellular cytoplasm cytoskeleton cell cortex endocytosis immune response activation of JUN kinase activity enzyme activator activity Rac protein signal transduction lamellipodium identical protein binding actin filament binding |
|
220003_at |
-0.191 |
5.856 |
-2.430 |
2.795e-02 |
0.529 |
-3.423 |
LRRC36 |
leucine rich repeat containing 36 |
16 |
65918247, 65938758 |
NM_018296 |
55282 |
16q22.1 |
Hs.125139 |
3 |
protein binding |
|
231195_at |
KLRG2 |
killer cell lectin-like receptor subfamily G, member 2 |
7 |
-138788627 |
AI492376 |
346689 |
7q34 |
Hs.17572 |
2 |
binding sugar binding membrane integral to membrane |
|
202920_at |
ANK2 |
ankyrin 2, neuronal |
4 |
113958687, 114190233 |
BF726212 |
287 |
4q25-q27 |
Hs.620557 |
39 |
protein binding cytoplasm cytoskeleton plasma membrane signal transduction basolateral plasma membrane apical plasma membrane M band |
|
235397_at |
NCRNA00174 |
non-protein coding RNA 174 |
7 |
-65478466 |
AA020789 |
285908 |
7q11.21 |
Hs.50755 |
3 |
|
|
241832_at |
FAM98A |
family with sequence similarity 98, member A |
2 |
-33662232 |
AI864271 |
25940 |
2p22.3 |
Hs.468140 |
2 |
|
|
210423_s_at |
SLC11A1 |
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 |
2 |
218954995 |
L32185 |
6556 |
2q35 |
Hs.591607 |
106 |
transporter activity iron ion binding vacuole plasma membrane integral to plasma membrane ion transport iron ion transport cellular cadmium ion homeostasis cellular iron ion homeostasis response to bacterium phagocytic vesicle membrane protein homodimerization activity transition metal ion transmembrane transporter activity metal ion:hydrogen antiporter activity cadmium ion transmembrane transport |
Lysosome |
203600_s_at |
C4orf8 |
chromosome 4 open reading frame 8 |
4 |
2596956 |
NM_003704 |
8603 |
4p16.3 |
Hs.652364 |
4 |
|
|
1559399_s_at |
0.539 |
4.963 |
2.368 |
3.154e-02 |
0.544 |
-3.523 |
ZCCHC10 |
zinc finger, CCHC domain containing 10 |
5 |
-132360575 |
BC015986 |
54819 |
5q31.1 |
Hs.29700 |
5 |
nucleic acid binding zinc ion binding metal ion binding |
|
242242_at |
USP6 |
ubiquitin specific peptidase 6 (Tre-2 oncogene) |
17 |
4972410 |
AA291110 |
9098 |
17p13 |
Hs.448851 |
21 |
nucleic acid binding cysteine-type endopeptidase activity ubiquitin thiolesterase activity Rab GTPase activator activity protein binding intracellular lysosome protein modification process ubiquitin-dependent protein catabolic process peptidase activity regulation of Rab GTPase activity |
|
228504_at |
SCN7A |
sodium channel, voltage-gated, type VII, alpha |
2 |
-166969784 |
AI828648 |
6332 |
2q21-q23 |
Hs.695947 |
11 |
voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport muscle contraction membrane integral to membrane sodium ion binding |
|
221692_s_at |
MRPL34 |
mitochondrial ribosomal protein L34 |
19 |
17277476 |
AB049652 |
64981 |
19p13.1 |
Hs.515242 |
6 |
structural constituent of ribosome intracellular mitochondrion mitochondrial large ribosomal subunit ribosome translation translation regulator activity |
|
203604_at |
ZNF516 |
zinc finger protein 516 |
18 |
-72200606 |
N38750 |
9658 |
18q23 |
Hs.709890 |
4 |
DNA binding intracellular nucleus cytoplasm zinc ion binding regulation of transcription metal ion binding |
|
226901_at |
0.533 |
6.607 |
3.275 |
5.035e-03 |
0.345 |
-1.973 |
C17orf58 |
chromosome 17 open reading frame 58 |
17 |
-63417678 |
AI214996 |
284018 |
17q24.2 |
Hs.90790 |
2 |
protein binding |
|
1562736_at |
-0.303 |
3.089 |
-2.294 |
3.645e-02 |
0.559 |
-3.643 |
LHX9 |
LIM homeobox 9 |
1 |
196148257, 196153139 |
AJ277914 |
56956 |
1q31-q32 |
Hs.442578 Hs.706475 |
6 |
transcription factor activity nucleus regulation of transcription, DNA-dependent zinc ion binding sequence-specific DNA binding metal ion binding |
|
205001_s_at |
DDX3Y |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked |
Y |
13525412, 13526092 |
AF000985 |
8653 |
Yq11 |
Hs.99120 |
19 |
nucleotide binding DNA binding RNA binding helicase activity ATP binding nucleus cytoplasm plasma membrane ATP-dependent helicase activity hydrolase activity |
RIG-I-like receptor signaling pathway |
225816_at |
PHF17 |
PHD finger protein 17 |
4 |
129950228, 129950228 |
AW138134 |
79960 |
4q26-q27 |
Hs.12420 |
14 |
histone acetyltransferase complex protein binding nucleus cytoplasm apoptosis response to stress zinc ion binding negative regulation of cell growth histone H3 acetylation histone H4-K5 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H4-K16 acetylation regulation of transcription metal ion binding |
|
1556771_a_at |
-0.272 |
5.092 |
-2.634 |
1.861e-02 |
0.486 |
-3.081 |
LOC415056 |
hypothetical LOC415056 |
9 |
34558009 |
BC038740 |
415056 |
9p13 |
Hs.662209 |
1 |
|
|
222243_s_at |
TOB2 |
transducer of ERBB2, 2 |
22 |
-40159437 |
AB051450 |
10766 |
22q13.2-q13.31 |
Hs.719120 |
9 |
nucleus cytoplasm female gamete generation negative regulation of cell proliferation regulation of gene expression vitamin D receptor binding negative regulation of osteoclast differentiation positive regulation of ossification |
|
212935_at |
MCF2L |
MCF.2 cell line derived transforming sequence-like |
13 |
112670757, 112681655 |
AB002360 |
23263 |
13q34 |
Hs.170422 Hs.597691 |
15 |
guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity intracellular cytoplasm mitochondrion plasma membrane intracellular signaling cascade regulation of Rho protein signal transduction |
|
217840_at |
DDX41 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 |
5 |
-176871183 |
NM_016222 |
51428 |
5q35.3 |
Hs.484288 |
14 |
nucleotide binding RNA binding helicase activity protein binding ATP binding nucleus spliceosomal complex mRNA processing apoptosis multicellular organismal development ATP-dependent helicase activity zinc ion binding RNA splicing hydrolase activity metal ion binding |
|
1563426_a_at |
0.334 |
4.127 |
2.241 |
4.035e-02 |
0.569 |
-3.727 |
LOC644613 |
hypothetical protein LOC644613 |
11 |
|
BC025792 |
644613 |
11q13.1 |
Hs.604039 |
1 |
|
|
215009_s_at |
SEC31A |
SEC31 homolog A (S. cerevisiae) |
4 |
-83958837 |
U92014 |
22872 |
4q21.22 |
Hs.370024 |
20 |
cytoplasm endoplasmic reticulum ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport protein transport membrane membrane organization vesicle-mediated transport COPII vesicle coat cytoplasmic vesicle calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion |
|
229369_at |
VSIG2 |
V-set and immunoglobulin domain containing 2 |
11 |
-124122579 |
AI201858 |
23584 |
11q24 |
Hs.112377 |
6 |
membrane fraction integral to plasma membrane membrane |
|
222969_at |
B3GALT1 |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 |
2 |
168383427 |
AF117222 |
8708 |
2q24.3 |
Hs.657258 |
13 |
Golgi membrane Golgi apparatus protein amino acid glycosylation galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity oligosaccharide biosynthetic process membrane integral to membrane transferase activity, transferring glycosyl groups manganese ion binding lipid glycosylation |
Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
1555998_at |
ATP5H |
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d |
17 |
-70546549 |
BE646027 |
10476 |
17q25 |
Hs.514465 |
13 |
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) mitochondrion ion transport hydrogen ion transmembrane transporter activity ATP synthesis coupled proton transport proton transport membrane ATPase activity |
Oxidative phosphorylation Metabolic pathways Alzheimer's disease Parkinson's disease Huntington's disease |
214663_at |
DSTYK |
dual serine/threonine and tyrosine protein kinase |
1 |
-203378254 |
AB007941 |
25778 |
1q32.1 |
Hs.6874 |
9 |
nucleotide binding protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm protein amino acid phosphorylation transferase activity |
|
206440_at |
LIN7A |
lin-7 homolog A (C. elegans) |
12 |
-79715301 |
NM_004664 |
8825 |
12q21 |
Hs.144333 |
17 |
protein binding plasma membrane tight junction protein complex assembly exocytosis neurotransmitter secretion protein transport basolateral plasma membrane synaptosome cell junction synapse postsynaptic membrane synaptic vesicle transport |
|
223253_at |
EPDR1 |
ependymin related protein 1 (zebrafish) |
7 |
37926687 |
BC000686 |
54749 |
7p14.1 |
Hs.563491 |
7 |
calcium ion binding extracellular region lysosome cell-matrix adhesion |
|
244522_at |
SYVN1 |
synovial apoptosis inhibitor 1, synoviolin |
11 |
-64651326 |
AA889078 |
84447 |
11q13 |
Hs.715498 |
30 |
in utero embryonic development protein binding nucleus nucleolus endoplasmic reticulum anti-apoptosis response to stress zinc ion binding membrane integral to membrane ligase activity acid-amino acid ligase activity modification-dependent protein catabolic process ER-associated protein catabolic process metal ion binding |
Ubiquitin mediated proteolysis |
241601_at |
WIPF3 |
WAS/WASL interacting protein family, member 3 |
7 |
29840865 |
H58488 |
644150 |
7p14.3 |
Hs.709280 |
5 |
actin binding cytoplasm multicellular organismal development spermatogenesis cell differentiation |
|
244120_at |
-0.197 |
4.109 |
-2.351 |
3.258e-02 |
0.548 |
-3.550 |
LOC340178 |
hypothetical protein LOC340178 |
6 |
|
AW183280 |
340178 |
6q27 |
Hs.343631 |
1 |
|
|
235524_at |
GARNL1 |
GTPase activating Rap/RanGAP domain-like 1 |
14 |
-35077308 |
BF062295 |
253959 |
14q13.2 |
Hs.113150 |
10 |
GTPase activator activity intracellular nucleus cytoplasm mitochondrion regulation of small GTPase mediated signal transduction |
|
200052_s_at |
0.326 |
8.345 |
2.158 |
4.734e-02 |
0.585 |
-3.859 |
ILF2 |
interleukin enhancer binding factor 2, 45kDa |
1 |
-151901137 |
NM_004515 |
3608 |
1q21.3 |
Hs.75117 |
23 |
DNA binding RNA polymerase II transcription factor activity double-stranded RNA binding protein binding nucleus nucleolus regulation of transcription positive regulation of transcription, DNA-dependent |
|
1565559_at |
MAGIX |
MAGI family member, X-linked |
X |
48906124, 48907213 |
AW418579 |
79917 |
Xp11.23 |
Hs.193170 |
3 |
protein binding |
|
1562365_at |
LOC286177 |
hypothetical protein LOC286177 |
8 |
|
BC036235 |
286177 |
8q12.1 |
Hs.385655 |
1 |
|
|
227312_at |
0.489 |
5.488 |
2.233 |
4.100e-02 |
0.571 |
-3.741 |
SNTB2 |
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
16 |
67778550 |
AI694536 |
6645 |
16q22-q23 |
Hs.461117 |
22 |
actin binding calcium ion binding calmodulin binding membrane fraction cytoplasm cytoskeleton microtubule dystrophin-associated glycoprotein complex membrane cell junction cytoplasmic vesicle synapse |
|
232892_at |
0.465 |
9.816 |
2.903 |
1.080e-02 |
0.421 |
-2.621 |
C20orf166 |
chromosome 20 open reading frame 166 |
20 |
60558104 |
AL449263 |
128826 |
20q13.33 |
Hs.86507 |
5 |
|
|
212861_at |
MFSD5 |
major facilitator superfamily domain containing 5 |
12 |
51932146 |
BF690150 |
84975 |
12q13.13 |
Hs.654660 |
7 |
transport membrane integral to membrane |
|
228544_s_at |
CSRP2BP |
CSRP2 binding protein |
20 |
18066526, 18073742 |
AA780252 |
57325 |
20p11.23 |
Hs.488051 |
8 |
protein binding nucleus cytoplasm N-acetyltransferase activity metabolic process LIM domain binding |
|
209472_at |
CCBL2 |
cysteine conjugate-beta lyase 2 |
1 |
-89174043 |
BC000819 |
56267 |
1p22.2 |
Hs.481898 |
8 |
biosynthetic process kynurenine-oxoglutarate transaminase activity lyase activity pyridoxal phosphate binding cysteine-S-conjugate beta-lyase activity |
|
204931_at |
TCF21 |
transcription factor 21 |
6 |
134251951, 134251952 |
NM_003206 |
6943 |
6pter-qter |
Hs.78061 |
16 |
branching involved in ureteric bud morphogenesis DNA binding protein binding nucleus mesoderm development sex differentiation organ morphogenesis transcription regulator activity regulation of transcription |
|
212211_at |
ANKRD17 |
ankyrin repeat domain 17 |
4 |
-74159365 |
AI986295 |
26057 |
4q13.3 |
Hs.644997 Hs.719092 |
10 |
RNA binding ATP binding nucleus cytoplasm mismatch repair mismatched DNA binding interspecies interaction between organisms |
|
238453_at |
0.341 |
4.115 |
2.829 |
1.255e-02 |
0.429 |
-2.749 |
FGFBP3 |
fibroblast growth factor binding protein 3 |
10 |
-93656324 |
AI628573 |
143282 |
10q23.32 |
Hs.466120 |
5 |
extracellular region growth factor binding |
|
1552913_at |
MAGEB18 |
melanoma antigen family B, 18 |
X |
26066383 |
NM_173699 |
286514 |
Xp21.3 |
Hs.350683 |
6 |
protein binding |
|
1561951_at |
-0.239 |
3.062 |
-2.238 |
4.057e-02 |
0.570 |
-3.732 |
SLC5A12 |
solute carrier family 5 (sodium/glucose cotransporter), member 12 |
11 |
-26645141 |
BC029048 |
159963 |
11p14.2 |
Hs.148907 |
3 |
transporter activity plasma membrane ion transport sodium ion transport symporter activity integral to membrane sodium ion binding |
|
232391_at |
ZNF461 |
zinc finger protein 461 |
19 |
-41820122 |
AB021641 |
92283 |
19q13.12 |
Hs.590972 |
5 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
210202_s_at |
BIN1 |
bridging integrator 1 |
2 |
-127522077, -127522076 |
U87558 |
274 |
2q14 |
Hs.193163 |
69 |
protein binding nucleus cytoplasm multicellular organismal development cell proliferation actin cytoskeleton regulation of endocytosis cell differentiation interspecies interaction between organisms |
|
228927_at |
ZNF397 |
zinc finger protein 397 |
18 |
31074995, 31075016 |
AW291411 |
84307 |
18q12.2 |
Hs.591061 |
8 |
transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
244617_at |
GPR26 |
G protein-coupled receptor 26 |
10 |
125415860 |
R46128 |
2849 |
10q26.13 |
Hs.12751 |
7 |
receptor activity G-protein coupled receptor activity plasma membrane signal transduction G-protein coupled receptor protein signaling pathway integral to membrane |
|
65517_at |
-0.313 |
6.223 |
-2.971 |
9.404e-03 |
0.401 |
-2.504 |
AP1M2 |
adaptor-related protein complex 1, mu 2 subunit |
19 |
-10544347 |
AA910946 |
10053 |
19p13.2 |
Hs.18894 |
28 |
protein binding Golgi apparatus cytosol protein targeting vesicle targeting membrane clathrin adaptor complex cytoplasmic vesicle |
Lysosome |
226944_at |
HTRA3 |
HtrA serine peptidase 3 |
4 |
8322391 |
AW518728 |
94031 |
4p16.1 |
Hs.479119 |
9 |
regulation of cell growth serine-type endopeptidase activity protein binding insulin-like growth factor binding extracellular region proteolysis peptidase activity |
|
1570228_at |
CFHR3 |
complement factor H-related 3 |
1 |
195010552 |
BC020680 |
10878 |
1q32 |
Hs.575869 Hs.709217 |
14 |
extracellular region extracellular space |
|
232119_at |
SYNPO2 |
synaptopodin 2 |
4 |
120029443, 120029443 |
BF984227 |
171024 |
4q26 |
Hs.655519 |
14 |
actin binding protein binding nucleus cytoplasm |
|
1558914_at |
PPPDE1 |
PPPDE peptidase domain containing 1 |
1 |
242882974 |
BC020640 |
51029 |
1q44 |
Hs.498317 |
5 |
|
|
219331_s_at |
KLHDC8A |
kelch domain containing 8A |
1 |
-203572270 |
NM_018203 |
55220 |
1q32.1 |
Hs.10414 |
3 |
|
|
216970_at |
RGS7 |
regulator of G-protein signaling 7 |
1 |
-239005439 |
AF090117 |
6000 |
1q23.1 1q43 |
Hs.655739 |
23 |
signal transducer activity protein binding cellular_component heterotrimeric G-protein complex intracellular signaling cascade regulation of G-protein coupled receptor protein signaling pathway negative regulation of signal transduction |
|
205205_at |
-0.328 |
4.962 |
-2.418 |
2.861e-02 |
0.532 |
-3.442 |
RELB |
v-rel reticuloendotheliosis viral oncogene homolog B |
19 |
50196551 |
NM_006509 |
5971 |
19q13.32 |
Hs.654402 |
89 |
transcription factor activity transcription corepressor activity protein binding nucleus regulation of transcription, DNA-dependent antigen processing and presentation myeloid dendritic cell differentiation T-helper 1 cell differentiation |
MAPK signaling pathway |
226160_at |
H6PD |
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
1 |
9217449 |
AW138757 |
9563 |
1p36 |
Hs.463511 |
25 |
glucose-6-phosphate dehydrogenase activity binding endoplasmic reticulum endoplasmic reticulum lumen microsome carbohydrate metabolic process glucose metabolic process pentose-phosphate shunt oxidoreductase activity hydrolase activity 6-phosphogluconolactonase activity glucose 1-dehydrogenase activity oxidation reduction |
Pentose phosphate pathway Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of plant hormones Metabolic pathways |
206802_at |
PAX5 |
paired box 5 |
9 |
-36828530 |
NM_016734 |
5079 |
9p13 |
Hs.654464 |
58 |
DNA binding nucleus transcription from RNA polymerase II promoter humoral immune response multicellular organismal development spermatogenesis nervous system development organ morphogenesis cell differentiation regulation of transcription |
|
207633_s_at |
-0.199 |
2.446 |
-2.154 |
4.765e-02 |
0.586 |
-3.864 |
MUSK |
muscle, skeletal, receptor tyrosine kinase |
9 |
112470907 |
NM_005592 |
4593 |
9q31.3-q32 |
Hs.521653 |
23 |
nucleotide binding transmembrane receptor protein tyrosine kinase activity receptor activity ATP binding integral to plasma membrane protein amino acid phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway multicellular organismal development muscle organ development membrane transferase activity |
|
200871_s_at |
0.443 |
10.456 |
2.304 |
3.570e-02 |
0.556 |
-3.626 |
PSAP |
prosaposin |
10 |
-73246060 |
NM_002778 |
5660 |
10q21-q22 |
Hs.523004 Hs.705948 |
76 |
extracellular space lysosome Golgi apparatus lipid metabolic process glycosphingolipid metabolic process lipid transport enzyme activator activity lipid binding integral to membrane |
Lysosome |
202363_at |
SPOCK1 |
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
5 |
-136338885 |
AF231124 |
6695 |
5q31 |
Hs.643338 |
15 |
calcium ion binding extracellular region proteinaceous extracellular matrix cell motion cell adhesion signal transduction multicellular organismal development nervous system development cell proliferation |
|
1562240_at |
0.273 |
3.645 |
2.717 |
1.575e-02 |
0.459 |
-2.941 |
PLXNA4 |
plexin A4 |
7 |
-131820060, -131718786, -131458630 |
AB046770 |
91584 |
7q32.3 |
Hs.511454 |
11 |
receptor activity intracellular signal transduction multicellular organismal development membrane integral to membrane |
|
1555618_s_at |
0.656 |
6.596 |
2.262 |
3.875e-02 |
0.567 |
-3.694 |
SAE1 |
SUMO1 activating enzyme subunit 1 |
19 |
52325919, 52325954, 52325971 |
AF110956 |
10055 |
19q13.32 |
Hs.515500 |
20 |
ubiquitin activating enzyme activity nucleus protein modification process protein C-terminus binding protein C-terminus binding enzyme activator activity metabolic process protein ubiquitination ligase activity modification-dependent protein catabolic process ATP-dependent protein binding protein heterodimerization activity |
Ubiquitin mediated proteolysis |
227393_at |
ANO9 |
anoctamin 9 |
11 |
-407929 |
AW084755 |
338440 |
11p15.5 |
Hs.501622 |
6 |
ion channel activity chloride channel activity calcium ion binding ion transport membrane integral to membrane chloride ion binding chloride channel complex |
|
220274_at |
IQCA1 |
IQ motif containing with AAA domain 1 |
2 |
-236897532 |
NM_024726 |
79781 |
2q37.2-q37.3 |
Hs.591594 Hs.621320 Hs.711488 |
6 |
nucleotide binding ATP binding |
|
210016_at |
MYT1L |
myelin transcription factor 1-like |
2 |
-1771891 |
BF223003 |
23040 |
2p25.3 |
Hs.434418 Hs.669852 |
7 |
transcription factor activity nucleus regulation of transcription, DNA-dependent multicellular organismal development nervous system development zinc ion binding cell differentiation metal ion binding |
|
205020_s_at |
ARL4A |
ADP-ribosylation factor-like 4A |
7 |
12693005, 12693485 |
NM_005738 |
10124 |
7p21-p15.3 |
Hs.245540 |
8 |
nucleotide binding GTPase activity protein binding GTP binding intracellular nucleus nucleolus small GTPase mediated signal transduction |
|
1567013_at |
0.284 |
4.757 |
2.476 |
2.550e-02 |
0.516 |
-3.346 |
NFE2L2 |
nuclear factor (erythroid-derived 2)-like 2 |
2 |
-177803279, -177803278 |
AF323119 |
4780 |
2q31 |
Hs.715540 |
141 |
transcription factor activity nucleus cytoplasm cytosol regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter sequence-specific DNA binding protein dimerization activity |
|
235643_at |
SAMD9L |
sterile alpha motif domain containing 9-like |
7 |
-92597303 |
BE886225 |
219285 |
7q21.2 |
Hs.489118 |
4 |
|
|
212053_at |
PDXDC1 |
pyridoxal-dependent decarboxylase domain containing 1 |
16 |
14976333 |
AK025504 |
23042 |
16p13.11 |
Hs.370781 |
6 |
protein binding lyase activity carboxy-lyase activity carboxylic acid metabolic process pyridoxal phosphate binding |
|
225536_at |
TMEM54 |
transmembrane protein 54 |
1 |
-33132782 |
AL545105 |
113452 |
1p35-p34 |
Hs.534521 |
4 |
molecular_function cellular_component biological_process membrane integral to membrane |
|
232717_at |
KALRN |
kalirin, RhoGEF kinase |
3 |
125296247, 125296247, 125296247, 125786195 |
AU147936 |
8997 |
3q21.2 |
Hs.8004 |
24 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity ATP binding intracellular cytoplasm protein amino acid phosphorylation intracellular signaling cascade nervous system development actin cytoskeleton vesicle-mediated transport transferase activity regulation of Rho protein signal transduction |
|
213443_at |
TRADD |
TNFRSF1A-associated via death domain |
16 |
-65745589 |
N36774 |
8717 |
16q22 |
Hs.460996 |
68 |
signal transducer activity cytoplasm cytosol cytoskeleton induction of apoptosis signal transduction activation of pro-apoptotic gene products intermediate filament binding kinase binding tumor necrosis factor-mediated signaling pathway identical protein binding positive regulation of I-kappaB kinase/NF-kappaB cascade receptor complex positive regulation of hair follicle development molecular adaptor activity death domain binding |
Apoptosis RIG-I-like receptor signaling pathway Adipocytokine signaling pathway |
211776_s_at |
0.660 |
5.004 |
2.361 |
3.195e-02 |
0.545 |
-3.534 |
EPB41L3 |
erythrocyte membrane protein band 4.1-like 3 |
18 |
-5382387 |
BC006141 |
23136 |
18p11.32 |
Hs.213394 |
39 |
actin binding structural molecule activity cytoplasm cytoskeleton plasma membrane cell-cell junction biological_process extrinsic to membrane cortical actin cytoskeleton organization |
Tight junction |
241938_at |
QKI |
quaking homolog, KH domain RNA binding (mouse) |
6 |
163755664, 163755664 |
AA935633 |
9444 |
6q26 6q26-q27 |
Hs.510324 Hs.593520 |
23 |
RNA binding protein binding nucleus nucleolus cytoplasm plasma membrane mRNA processing regulation of translation transport multicellular organismal development RNA splicing SH3 domain binding cell differentiation mRNA transport |
|
221272_s_at |
C1orf21 |
chromosome 1 open reading frame 21 |
1 |
182622772 |
NM_030806 |
81563 |
1q25 |
Hs.497159 Hs.719188 |
8 |
|
|
204059_s_at |
ME1 |
malic enzyme 1, NADP(+)-dependent, cytosolic |
6 |
-83976828 |
NM_002395 |
4199 |
6q12 |
Hs.21160 |
24 |
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity binding nucleus nucleolus cytoplasm cytosol carbohydrate metabolic process malate metabolic process NADP biosynthetic process electron carrier activity response to hormone stimulus response to carbohydrate stimulus oxidoreductase activity manganese ion binding ADP binding metal ion binding NADP or NADPH binding NAD or NADH binding oxidation reduction |
Pyruvate metabolism Carbon fixation in photosynthetic organisms Biosynthesis of terpenoids and steroids Biosynthesis of alkaloids derived from shikimate pathway Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid Biosynthesis of alkaloids derived from histidine and purine Biosynthesis of alkaloids derived from terpenoid and polyketide Metabolic pathways PPAR signaling pathway |
218358_at |
CRELD2 |
cysteine-rich with EGF-like domains 2 |
22 |
48698286 |
NM_024324 |
79174 |
22q13.33 |
Hs.211282 |
9 |
calcium ion binding extracellular region endoplasmic reticulum |
|
213025_at |
THUMPD1 |
THUMP domain containing 1 |
16 |
-20652489 |
AL134904 |
55623 |
16p12.3 |
Hs.460232 |
5 |
|
|
226975_at |
0.655 |
6.679 |
2.139 |
4.904e-02 |
0.590 |
-3.888 |
RNPC3 |
RNA-binding region (RNP1, RRM) containing 3 |
1 |
103841165 |
BF116157 |
55599 |
1p21 |
Hs.632423 Hs.632430 |
7 |
nucleotide binding RNA binding nucleus U12-type spliceosomal complex mRNA processing RNA splicing |
|
208436_s_at |
IRF7 |
interferon regulatory factor 7 |
11 |
-602554, -602554 |
NM_004030 |
3665 |
11p15.5 |
Hs.166120 |
46 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity specific RNA polymerase II transcription factor activity nucleus cytoplasm regulation of transcription, DNA-dependent response to virus interspecies interaction between organisms |
Toll-like receptor signaling pathway RIG-I-like receptor signaling pathway |
206950_at |
SCN9A |
sodium channel, voltage-gated, type IX, alpha subunit |
2 |
-166759942 |
NM_002977 |
6335 |
2q24 |
Hs.439145 |
46 |
voltage-gated sodium channel complex voltage-gated ion channel activity voltage-gated sodium channel activity ion transport sodium ion transport inflammatory response post-embryonic development membrane integral to membrane sodium ion binding behavioral response to pain |
|
230864_at |
MGC42105 |
serine/threonine-protein kinase NIM1 |
5 |
43228083 |
BF222940 |
167359 |
5p12 |
Hs.25845 |
4 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity |
|
215000_s_at |
FEZ2 |
fasciculation and elongation protein zeta 2 (zygin II) |
2 |
-36632904 |
AL117593 |
9637 |
2p21 |
Hs.258563 |
9 |
protein binding signal transduction nervous system development axon guidance |
|
224571_at |
IRF2BP2 |
interferon regulatory factor 2 binding protein 2 |
1 |
-232806637 |
BF968057 |
359948 |
1q42.3 |
Hs.693837 |
5 |
nucleus regulation of transcription |
|
202869_at |
OAS1 |
2',5'-oligoadenylate synthetase 1, 40/46kDa |
12 |
111829121, 111829121 |
NM_016816 |
4938 |
12q24.1 |
Hs.524760 |
44 |
nucleotide binding RNA binding ATP binding nucleus cytoplasm mitochondrion endoplasmic reticulum microsome nucleobase, nucleoside, nucleotide and nucleic acid metabolic process immune response transferase activity nucleotidyltransferase activity |
|
222486_s_at |
0.970 |
5.462 |
2.727 |
1.546e-02 |
0.458 |
-2.925 |
ADAMTS1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
21 |
-27130476 |
AF060152 |
9510 |
21q21.2 |
Hs.643357 |
44 |
ovulation from ovarian follicle kidney development metalloendopeptidase activity protein binding extracellular region basement membrane proteolysis integrin-mediated signaling pathway heparin binding peptidase activity zinc ion binding negative regulation of cell proliferation cytoplasmic vesicle metal ion binding heart trabecula formation |
|
209122_at |
0.746 |
8.438 |
3.965 |
1.215e-03 |
0.234 |
-0.765 |
PLIN2 |
perilipin 2 |
9 |
-19105758 |
BC005127 |
123 |
9p22.1 |
Hs.3416 |
31 |
protein binding extracellular region nucleus cytoplasm endoplasmic reticulum lipid particle plasma membrane long-chain fatty acid transport lipid storage |
|
206432_at |
HAS2 |
hyaluronan synthase 2 |
8 |
-122694451 |
NM_005328 |
3037 |
8q24.12 |
Hs.159226 |
26 |
integral to plasma membrane membrane transferase activity, transferring glycosyl groups hyaluronan synthase activity |
|
231271_x_at |
0.560 |
4.905 |
3.904 |
1.375e-03 |
0.245 |
-0.870 |
NMRAL1 |
NmrA-like family domain containing 1 |
16 |
-4451695 |
AI080701 |
57407 |
16p13.3 |
Hs.288969 |
8 |
binding regulation of nitrogen utilization oxidoreductase activity transcription repressor activity oxidation reduction |
|
221253_s_at |
0.443 |
7.692 |
2.974 |
9.339e-03 |
0.401 |
-2.498 |
TXNDC5 |
thioredoxin domain containing 5 (endoplasmic reticulum) |
6 |
-7826752, -7826750 |
NM_030810 |
81567 |
6p24.3 |
Hs.150837 |
12 |
endoplasmic reticulum endoplasmic reticulum lumen anti-apoptosis isomerase activity cell redox homeostasis |
|
230009_at |
FAM118B |
family with sequence similarity 118, member B |
11 |
125586828 |
AI936072 |
79607 |
11q24.2 |
Hs.276315 |
2 |
|
|
232214_x_at |
-0.247 |
6.997 |
-2.276 |
3.772e-02 |
0.564 |
-3.672 |
ZNF554 |
zinc finger protein 554 |
19 |
2770871 |
BC000113 |
115196 |
19p13.3 |
Hs.307043 |
4 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
1555216_a_at |
LOC645722 |
hypothetical LOC645722 |
17 |
|
BC009278 |
645722 |
17q23.2 |
|
|
|
|
222934_s_at |
CLEC4E |
C-type lectin domain family 4, member E |
12 |
-8577167 |
BC000715 |
26253 |
12p13.31 |
Hs.236516 |
9 |
binding sugar binding immune response membrane integral to membrane |
|
219068_x_at |
ATAD3A |
ATPase family, AAA domain containing 3A |
1 |
1437417 |
NM_018188 |
55210 |
1p36.33 |
Hs.655253 |
9 |
nucleotide binding protein binding ATP binding nucleoside-triphosphatase activity |
|
238633_at |
0.534 |
6.011 |
2.302 |
3.586e-02 |
0.557 |
-3.630 |
EPC1 |
enhancer of polycomb homolog 1 (Drosophila) |
10 |
-32597864 |
W93523 |
80314 |
10p11 |
Hs.167805 Hs.510635 Hs.621281 |
16 |
negative regulation of transcription from RNA polymerase II promoter histone acetyltransferase activity nucleus nucleoplasm transcription activator activity transcription repressor activity chromatin modification nuclear membrane Piccolo NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth histone H4 acetylation histone H2A acetylation regulation of transcription negative regulation of gene expression, epigenetic positive regulation of transcription from RNA polymerase II promoter |
|
1562411_at |
MYLK3 |
myosin light chain kinase 3 |
16 |
-45293694 |
AJ247087 |
91807 |
16q11.2 |
Hs.130465 |
6 |
nucleotide binding magnesium ion binding myosin light chain kinase activity ATP binding protein amino acid phosphorylation transferase activity |
Calcium signaling pathway Vascular smooth muscle contraction Focal adhesion Regulation of actin cytoskeleton |
230656_s_at |
CIRH1A |
cirrhosis, autosomal recessive 1A (cirhin) |
16 |
67723999 |
AL578336 |
84916 |
16q22.1 |
Hs.461113 |
13 |
molecular_function nucleus nucleolus biological_process |
|
226161_at |
SLC30A6 |
solute carrier family 30 (zinc transporter), member 6 |
2 |
32244436 |
BF793552 |
55676 |
2p22.3 |
Hs.23248 |
7 |
Golgi apparatus cation transport zinc ion transport zinc ion binding cation transmembrane transporter activity membrane integral to membrane |
|
228760_at |
SFRS2B |
splicing factor, arginine/serine-rich 2B |
11 |
94439703 |
AV725947 |
10929 |
11q22 |
Hs.476680 Hs.713908 |
6 |
nucleotide binding RNA binding nucleus mRNA processing RNA splicing |
|
221680_s_at |
ETV7 |
ets variant 7 |
6 |
-36441948 |
AF147782 |
51513 |
6p21 |
Hs.272398 |
11 |
transcription factor activity specific RNA polymerase II transcription factor activity protein binding nucleus regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter organ morphogenesis sequence-specific DNA binding |
Dorso-ventral axis formation |
220211_at |
FLJ13224 |
hypothetical protein FLJ13224 |
12 |
31368516 |
NM_024799 |
79857 |
12p11.21 |
Hs.505154 Hs.534485 |
2 |
|
|
201585_s_at |
0.323 |
7.075 |
3.084 |
7.453e-03 |
0.376 |
-2.306 |
SFPQ |
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) |
1 |
-35421789 |
BG035151 |
6421 |
1p34.3 |
Hs.355934 |
47 |
nucleotide binding DNA binding RNA binding protein binding nucleus DNA repair DNA recombination mRNA processing response to DNA damage stimulus RNA splicing nuclear matrix regulation of transcription |
|
206001_at |
-0.218 |
4.812 |
-2.370 |
3.145e-02 |
0.543 |
-3.521 |
NPY |
neuropeptide Y |
7 |
24290333 |
NM_000905 |
4852 |
7p15.1 |
Hs.1832 |
144 |
G-protein-coupled receptor binding G-protein coupled receptor activity neuropeptide hormone activity calcium channel regulator activity extracellular region extracellular space cell calcium ion transport cell motion G-protein signaling, coupled to cyclic nucleotide second messenger neuropeptide signaling pathway synaptic transmission digestion regulation of blood pressure cell proliferation adult feeding behavior positive regulation of appetite |
Adipocytokine signaling pathway |
216594_x_at |
AKR1C1 |
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) |
10 |
4995453 |
S68290 |
1645 |
10p15-p14 |
Hs.460260 |
37 |
aldo-keto reductase activity cytoplasm cytosol xenobiotic metabolic process digestion bile acid metabolic process bile acid and bile salt transport oxidoreductase activity intestinal cholesterol absorption carboxylic acid binding bile acid binding cholesterol homeostasis response to organophosphorus 20-alpha-hydroxysteroid dehydrogenase activity 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity indanol dehydrogenase activity protein homooligomerization oxidation reduction |
Metabolism of xenobiotics by cytochrome P450 |
215010_s_at |
BRSK2 |
BR serine/threonine kinase 2 |
11 |
1367704 |
AJ006701 |
9024 |
11p15.5 |
Hs.170819 |
15 |
nucleotide binding magnesium ion binding protein serine/threonine kinase activity ATP binding protein amino acid phosphorylation transferase activity establishment of cell polarity neuron differentiation |
|
232141_at |
0.368 |
6.465 |
3.110 |
7.068e-03 |
0.372 |
-2.261 |
U2AF1 |
U2 small nuclear RNA auxiliary factor 1 |
21 |
-43386134 |
AU144161 |
7307 |
21q22.3 |
Hs.365116 |
47 |
nucleotide binding nuclear mRNA splicing, via spliceosome nuclear mRNA splicing, via spliceosome RNA binding protein binding nucleus spliceosomal complex zinc ion binding RNA splicing Cajal body metal ion binding RS domain binding |
|
1552535_at |
-0.206 |
5.611 |
-2.247 |
3.988e-02 |
0.568 |
-3.718 |
CLDN19 |
claudin 19 |
1 |
-42971350 |
NM_148960 |
149461 |
1p34.2 |
Hs.496270 |
11 |
magnesium ion binding structural molecule activity plasma membrane tight junction visual perception integral to membrane basolateral plasma membrane calcium-independent cell-cell adhesion cell junction identical protein binding response to stimulus |
Cell adhesion molecules (CAMs) Tight junction Leukocyte transendothelial migration |
218676_s_at |
PCTP |
phosphatidylcholine transfer protein |
17 |
51183354 |
NM_021213 |
58488 |
17q21-q24 |
Hs.285218 |
9 |
cytoplasm cytosol cytosol lipid binding phosphatidylcholine transmembrane transporter activity phosphatidylcholine transmembrane transporter activity phospholipid transport phosphatidylcholine binding |
|
206804_at |
CD3G |
CD3g molecule, gamma (CD3-TCR complex) |
11 |
117720268 |
NM_000073 |
917 |
11q23 |
Hs.2259 |
63 |
transmembrane receptor activity plasma membrane integral to plasma membrane protein complex assembly establishment or maintenance of cell polarity cell surface receptor linked signal transduction protein transport receptor signaling complex scaffold activity T cell receptor complex T cell activation T cell receptor binding regulation of apoptosis protein heterodimerization activity |
Hematopoietic cell lineage T cell receptor signaling pathway |
218533_s_at |
UCKL1 |
uridine-cytidine kinase 1-like 1 |
20 |
-62041631 |
NM_017859 |
54963 |
20q13.33 |
Hs.504998 |
9 |
nucleotide binding uridine kinase activity ATP binding nucleus cytoplasm endoplasmic reticulum metabolic process kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor interspecies interaction between organisms |
Pyrimidine metabolism Drug metabolism - other enzymes Metabolic pathways |
223453_s_at |
ATL3 |
atlastin GTPase 3 |
11 |
-63153012 |
BC005096 |
25923 |
11q12.3-q13.1 |
Hs.356719 |
4 |
nucleotide binding GTPase activity GTP binding membrane integral to membrane |
|
211171_s_at |
PDE10A |
phosphodiesterase 10A |
6 |
-165660767 |
AB026816 |
10846 |
6q26 |
Hs.348762 |
13 |
nucleotide binding magnesium ion binding cytoplasm signal transduction zinc ion binding hydrolase activity cAMP binding cGMP binding 3',5'-cyclic-GMP phosphodiesterase activity |
Purine metabolism |
224785_at |
FAM100B |
family with sequence similarity 100, member B |
17 |
71772880 |
AI024869 |
283991 |
17q25.1 |
Hs.719201 |
2 |
|
|
235519_at |
FOXK1 |
forkhead box K1 |
7 |
4688455 |
AW007929 |
221937 |
7p22.1 |
Hs.708095 |
10 |
transcription factor activity protein binding nucleus nucleolus regulation of transcription from RNA polymerase II promoter multicellular organismal development muscle organ development transcription activator activity transcription repressor activity cell differentiation sequence-specific DNA binding negative regulation of transcription, DNA-dependent positive regulation of transcription, DNA-dependent |
|
215530_at |
FANCA |
Fanconi anemia, complementation group A |
16 |
-88392267, -88331459 |
BG484069 |
2175 |
16q24.3 |
Hs.719210 |
81 |
protein binding nucleus cytoplasm DNA repair protein complex assembly response to DNA damage stimulus |
|
213935_at |
ABHD5 |
abhydrolase domain containing 5 |
3 |
43707378 |
AF007132 |
51099 |
3p21 |
Hs.19385 |
14 |
1-acylglycerol-3-phosphate O-acyltransferase activity triacylglycerol lipase activity protein binding cytoplasm cytosol lipid metabolic process fatty acid metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process negative regulation of sequestering of triglyceride positive regulation of triglyceride catabolic process monolayer-surrounded lipid storage body transferase activity hydrolase activity cell differentiation lysophosphatidic acid acyltransferase activity |
|
1566860_at |
-0.481 |
2.619 |
-4.045 |
1.030e-03 |
0.225 |
-0.625 |
LOC145663 |
hypothetical protein LOC145663 |
15 |
|
AK056979 |
145663 |
15q15.1 |
Hs.75335 |
1 |
|
|
205929_at |
GPA33 |
glycoprotein A33 (transmembrane) |
1 |
-165288705 |
NM_005814 |
10223 |
1q24.1 |
Hs.651244 |
11 |
receptor activity plasma membrane integral to plasma membrane |
|
221509_at |
DENR |
density-regulated protein |
12 |
121803323 |
AB014731 |
8562 |
12q24.31 |
Hs.22393 |
6 |
molecular_function translation initiation factor activity cellular_component translational initiation biological_process |
|
203486_s_at |
ARMC8 |
armadillo repeat containing 8 |
3 |
139388837, 139388837 |
BF195973 |
25852 |
3q22.3 |
Hs.719108 |
4 |
binding |
|
1558168_at |
C3orf47 |
chromosome 3 open reading frame 47 |
3 |
130517803 |
AL040547 |
339942 |
3q21.3 |
Hs.450096 Hs.75307 |
5 |
|
|
238551_at |
0.271 |
3.746 |
2.654 |
1.787e-02 |
0.475 |
-3.047 |
FUT11 |
fucosyltransferase 11 (alpha (1,3) fucosyltransferase) |
10 |
75202054 |
BF541967 |
170384 |
10q22.2 |
Hs.588854 |
4 |
Golgi membrane Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups alpha(1,3)-fucosyltransferase activity |
|
224533_s_at |
C6orf142 |
chromosome 6 open reading frame 142 |
6 |
53991672 |
M77498 |
90523 |
6p12.1 |
Hs.382212 Hs.591803 |
10 |
|
|
212807_s_at |
SORT1 |
sortilin 1 |
1 |
-109653714 |
BF447105 |
6272 |
1p21.3-p13.1 |
Hs.485195 Hs.703487 |
47 |
ossification receptor activity nucleus lysosome early endosome endoplasmic reticulum microsome Golgi apparatus plasma membrane coated pit transport Golgi to endosome transport endocytosis neuropeptide signaling pathway multicellular organismal development endosome to lysosome transport induction of apoptosis by extracellular signals cell surface nerve growth factor receptor activity regulation of gene expression myotube differentiation integral to membrane cytoplasmic membrane-bounded vesicle vesicle organization enzyme binding clathrin-coated vesicle cell differentiation neurotensin receptor activity, non-G-protein coupled endosome transport via multivesicular body sorting pathway response to insulin stimulus negative regulation of apoptosis glucose import nerve growth factor receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity |
Lysosome Neurotrophin signaling pathway |
234583_at |
CHL1 |
cell adhesion molecule with homology to L1CAM (close homolog of L1) |
3 |
213649 |
AL359583 |
10752 |
3p26.1 |
Hs.148909 |
11 |
protein binding extracellular region proteinaceous extracellular matrix plasma membrane cell adhesion signal transduction multicellular organismal development nervous system development integral to membrane cell differentiation |
|
228561_at |
CDC37L1 |
cell division cycle 37 homolog (S. cerevisiae)-like 1 |
9 |
4669565 |
BF510563 |
55664 |
9p24.1 |
Hs.561954 |
6 |
protein binding cytoplasm |
|
36475_at |
GCAT |
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) |
22 |
36533900 |
Z97630 |
23464 |
22q13.1 |
Hs.54609 |
6 |
mitochondrion mitochondrial inner membrane cellular amino acid metabolic process acyltransferase activity glycine C-acetyltransferase activity biosynthetic process transferase activity, transferring nitrogenous groups pyridoxal phosphate binding |
Glycine, serine and threonine metabolism |
1567270_at |
OR4C1P |
olfactory receptor, family 4, subfamily C, member 1 pseudogene |
11 |
|
X64985 |
26242 |
11q11 |
Hs.550274 |
1 |
|
|
233461_x_at |
0.712 |
5.286 |
3.197 |
5.918e-03 |
0.357 |
-2.110 |
ZNF226 |
zinc finger protein 226 |
19 |
49361088, 49361088, 49361096, 49361156 |
AK023091 |
7769 |
19q13.2 |
Hs.145956 |
6 |
DNA binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
200680_x_at |
HMGB1 |
high-mobility group box 1 |
13 |
-29930878 |
NM_002128 |
3146 |
13q12 |
Hs.593339 Hs.596078 Hs.644368 |
157 |
condensed chromosome nucleus nucleolus DNA unwinding during replication DNA repair base-excision repair, DNA ligation DNA recombination chromatin organization regulation of transcription from RNA polymerase II promoter anti-apoptosis signal transduction transcription factor binding DNA bending activity negative regulation of transcriptional preinitiation complex assembly |
Base excision repair |
226895_at |
NFIC |
nuclear factor I/C (CCAAT-binding transcription factor) |
19 |
3310615, 3317572 |
AW134798 |
4782 |
19p13.3 |
Hs.170131 |
23 |
negative regulation of transcription from RNA polymerase II promoter transcription factor activity intracellular nucleus DNA replication regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter |
|
213995_at |
ATP5S |
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) |
14 |
49848796, 49848796 |
AW195882 |
27109 |
14q21.3 |
Hs.438489 |
12 |
mitochondrion mitochondrial inner membrane ATP biosynthetic process ion transport hydrogen ion transmembrane transporter activity proton transport membrane proton-transporting ATP synthase complex, coupling factor F(o) |
|
203570_at |
1.063 |
4.863 |
4.166 |
8.048e-04 |
0.214 |
-0.417 |
LOXL1 |
lysyl oxidase-like 1 |
15 |
72005841 |
NM_005576 |
4016 |
15q22 15q24-q25 |
Hs.65436 |
48 |
copper ion binding protein binding extracellular region proteinaceous extracellular matrix extracellular space oxidoreductase activity oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor protein amino acid deamination metal ion binding oxidation reduction |
|
223414_s_at |
LYAR |
Ly1 antibody reactive homolog (mouse) |
4 |
-4320331, -4320331 |
AL136750 |
55646 |
4p16.3 |
Hs.425427 |
14 |
protein binding nucleus nucleolus zinc ion binding metal ion binding |
|
209062_x_at |
NCOA3 |
nuclear receptor coactivator 3 |
20 |
45564063 |
AF010227 |
8202 |
20q12 |
Hs.592142 |
140 |
transcription coactivator activity histone acetyltransferase activity signal transducer activity nucleus cytoplasm signal transduction acyltransferase activity transferase activity androgen receptor signaling pathway transcription regulator activity positive regulation of transcription, DNA-dependent thyroid hormone receptor binding protein N-terminus binding androgen receptor binding |
|
208836_at |
0.367 |
7.577 |
2.371 |
3.138e-02 |
0.543 |
-3.519 |
ATP1B3 |
ATPase, Na+/K+ transporting, beta 3 polypeptide |
3 |
143078159 |
U51478 |
483 |
3q23 |
Hs.477789 |
13 |
sodium:potassium-exchanging ATPase activity protein binding cytoplasm sodium:potassium-exchanging ATPase complex ATP biosynthetic process ion transport potassium ion transport sodium ion transport membrane integral to membrane potassium ion binding sodium ion binding melanosome |
Cardiac muscle contraction |
226436_at |
0.689 |
6.226 |
2.418 |
2.862e-02 |
0.532 |
-3.442 |
RASSF4 |
Ras association (RalGDS/AF-6) domain family member 4 |
10 |
44775224 |
N49935 |
83937 |
10q11.21 |
Hs.522895 |
9 |
protein binding cell cycle signal transduction |
|
207078_at |
MED6 |
mediator complex subunit 6 |
14 |
-70120709 |
NM_005466 |
10001 |
14q24.2 |
Hs.497353 |
22 |
RNA polymerase II transcription factor activity transcription coactivator activity nucleus RNA polymerase II transcription mediator activity regulation of transcription positive regulation of transcription from RNA polymerase II promoter |
|
223297_at |
0.380 |
7.139 |
2.239 |
4.051e-02 |
0.570 |
-3.731 |
AMMECR1L |
AMME chromosomal region gene 1-like |
2 |
-128335675 |
BC004208 |
83607 |
2q21 |
Hs.546449 |
3 |
|
|
218626_at |
EIF4ENIF1 |
eukaryotic translation initiation factor 4E nuclear import factor 1 |
22 |
-30165354 |
NM_019843 |
56478 |
22q11.2 |
Hs.517559 |
15 |
protein binding nucleus cytoplasm protein transporter activity protein transport |
|
215640_at |
TBC1D2B |
TBC1 domain family, member 2B |
15 |
-76074381 |
AK000173 |
23102 |
15q24.3-q25.1 |
Hs.719242 |
2 |
GTPase activator activity Rab GTPase activator activity intracellular regulation of Rab GTPase activity |
|
200810_s_at |
CIRBP |
cold inducible RNA binding protein |
19 |
1220266, 1220266 |
NM_001280 |
1153 |
19p13.3 |
Hs.634522 Hs.664127 |
17 |
nucleotide binding RNA binding protein binding nucleus nucleoplasm response to cold |
|
1568828_at |
LOC730441 |
similar to trypsin X5 |
7 |
|
BC039387 |
730441 |
7q34 |
Hs.604069 |
1 |
|
|
218645_at |
ZNF277 |
zinc finger protein 277 |
7 |
111633878 |
NM_021994 |
11179 |
7q31.1 |
Hs.655904 |
10 |
transcription factor activity protein binding intracellular nucleus regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
213566_at |
0.546 |
3.497 |
2.164 |
4.678e-02 |
0.583 |
-3.849 |
RNASE6 |
ribonuclease, RNase A family, k6 |
14 |
20319049 |
NM_005615 |
6039 |
14q11.2 |
Hs.23262 |
6 |
nucleic acid binding endonuclease activity pancreatic ribonuclease activity ribonuclease activity extracellular region RNA catabolic process defense response hydrolase activity |
|
229758_at |
TIGD5 |
tigger transposable element derived 5 |
8 |
144751363 |
AW168771 |
84948 |
8q24.3 |
Hs.71574 |
4 |
chromosome, centromeric region DNA binding nucleus regulation of transcription |
|
1552299_at |
AKD1 |
adenylate kinase domain containing 1 |
6 |
-110059592, -109920751 |
NM_145025 |
221264 |
6q21 |
Hs.205144 Hs.335027 Hs.486169 |
6 |
ATP binding nucleobase, nucleoside, nucleotide and nucleic acid metabolic process nucleobase, nucleoside, nucleotide kinase activity |
|
1560553_at |
TIAF1 |
TGFB1-induced anti-apoptotic factor 1 |
17 |
-24424664 |
BC011938 |
9220 |
17q11.2 |
Hs.462590 |
15 |
molecular_function nucleus apoptosis anti-apoptosis I-kappaB kinase/NF-kappaB cascade |
|
212775_at |
OBSL1 |
obscurin-like 1 |
2 |
-220123708 |
AI978623 |
23363 |
2q35 |
Hs.526594 |
10 |
cytoskeleton organization cytoskeletal adaptor activity intercalated disc Z disc M band perinuclear region of cytoplasm cardiac myofibril assembly |
|
210398_x_at |
FUT6 |
fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
19 |
-5781636 |
M98825 |
2528 |
19p13.3 |
Hs.631846 Hs.705615 |
19 |
Golgi apparatus protein amino acid glycosylation membrane integral to membrane transferase activity, transferring glycosyl groups 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity L-fucose catabolic process alpha(1,3)-fucosyltransferase activity |
Glycosphingolipid biosynthesis - lacto and neolacto series Metabolic pathways |
220403_s_at |
TP53AIP1 |
tumor protein p53 regulated apoptosis inducing protein 1 |
11 |
-128310479 |
NM_022112 |
63970 |
11q24 |
Hs.160953 Hs.711194 |
11 |
molecular_function mitochondrion apoptosis |
p53 signaling pathway |
223968_at |
ZNF44 |
zinc finger protein 44 |
19 |
-12243624 |
BC001868 |
51710 |
19p13.2 |
Hs.296731 Hs.693933 |
10 |
DNA binding protein binding intracellular nucleus cytoplasm cytoskeleton regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
226312_at |
0.480 |
7.938 |
3.036 |
8.238e-03 |
0.387 |
-2.392 |
RICTOR |
RPTOR independent companion of MTOR, complex 2 |
5 |
-38973779 |
BF940270 |
253260 |
5p13.1 |
Hs.407926 |
21 |
guanyl-nucleotide exchange factor activity protein binding intracellular embryonic development positive regulation of actin filament polymerization actin cytoskeleton reorganization TORC2 complex positive regulation of TOR signaling pathway regulation of Rac GTPase activity regulation of actin cytoskeleton organization positive regulation of peptidyl-tyrosine phosphorylation regulation of small GTPase mediated signal transduction regulation of protein kinase B signaling cascade |
mTOR signaling pathway |
237847_at |
NTN1 |
netrin 1 |
17 |
8865583 |
BF058964 |
9423 |
17p13-p12 |
Hs.660885 |
29 |
neuron migration protein binding extracellular region basement membrane cytoplasm apoptosis axon guidance positive regulation of cell proliferation regulation of cell migration negative regulation of axon extension mammary gland development establishment of nucleus localization positive regulation of axon extension |
Axon guidance |
234220_at |
CADPS |
Ca++-dependent secretion activator |
3 |
-62359061 |
AK024536 |
8618 |
3p14.2 |
Hs.654933 |
14 |
calcium ion binding cytosol exocytosis lipid binding protein transport membrane cell junction cytoplasmic vesicle synapse |
|
239314_at |
NHLRC3 |
NHL repeat containing 3 |
13 |
38510454 |
AV688972 |
387921 |
13q13.3 |
Hs.507783 |
1 |
extracellular region |
|
201234_at |
0.388 |
7.620 |
2.719 |
1.569e-02 |
0.459 |
-2.937 |
ILK |
integrin-linked kinase |
11 |
6581539, 6581782 |
NM_004517 |
3611 |
11p15.5-p15.4 |
Hs.5158 Hs.706355 |
115 |
nucleotide binding branching involved in ureteric bud morphogenesis protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding cytoplasm plasma membrane focal adhesion protein amino acid phosphorylation cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation regulation of signal transduction transferase activity cell junction establishment or maintenance of epithelial cell apical/basal polarity |
PPAR signaling pathway Focal adhesion Endometrial cancer |
238813_at |
ALAS2 |
aminolevulinate, delta-, synthase 2 |
X |
-55052213 |
AI910842 |
212 |
Xp11.21 |
Hs.522666 Hs.555936 |
29 |
response to hypoxia 5-aminolevulinate synthase activity protein binding mitochondrion mitochondrial inner membrane mitochondrial matrix porphyrin metabolic process heme biosynthetic process heme biosynthetic process cellular iron ion homeostasis acyltransferase activity glycine binding transferase activity, transferring nitrogenous groups pyridoxal phosphate binding erythrocyte differentiation erythrocyte differentiation oxygen homeostasis tetrapyrrole biosynthetic process hemoglobin biosynthetic process coenzyme binding |
Glycine, serine and threonine metabolism Porphyrin and chlorophyll metabolism Metabolic pathways |
1554985_at |
ZNF396 |
zinc finger protein 396 |
18 |
-31200658 |
BC031580 |
252884 |
18q12 |
Hs.351005 |
3 |
transcription factor activity intracellular nucleus cytoplasm regulation of transcription, DNA-dependent zinc ion binding metal ion binding |
|
239040_at |
HNRNPD |
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
4 |
-83493490 |
AW967813 |
3184 |
4q21.1-q21.2 |
Hs.480073 |
64 |
nucleotide binding nuclear mRNA splicing, via spliceosome DNA binding RNA binding RNA binding protein binding nucleus chromosome regulation of transcription, DNA-dependent RNA processing RNA catabolic process biological_process transcription activator activity heterogeneous nuclear ribonucleoprotein complex telomeric DNA binding |
|
202868_s_at |
POP4 |
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) |
19 |
34789009 |
NM_006627 |
10775 |
19q12 |
Hs.412870 |
13 |
ribonuclease MRP complex RNA binding ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolus rRNA processing mRNA cleavage tRNA processing hydrolase activity ribonuclease P complex identical protein binding |
|
223789_s_at |
GTPBP2 |
GTP binding protein 2 |
6 |
-43696195 |
AF116627 |
54676 |
6p21-p12 |
Hs.485449 |
7 |
nucleotide binding GTPase activity GTP binding |
|
220925_at |
MAK10 |
MAK10 homolog, amino-acid N-acetyltransferase subunit (S. cerevisiae) |
9 |
87745876 |
NM_021929 |
60560 |
9q21.33 |
Hs.436098 |
7 |
protein binding cytoplasm smooth muscle cell proliferation |
|
1554068_s_at |
C12orf66 |
chromosome 12 open reading frame 66 |
12 |
-62872685 |
BC036246 |
144577 |
12q14.2 |
Hs.505871 |
3 |
|
|
240289_at |
LOC100131683 |
hypothetical protein LOC100131683 |
4 |
|
W86910 |
100131683 |
4q35.1 |
Hs.442702 |
|
|
|
200851_s_at |
0.221 |
8.609 |
2.178 |
4.557e-02 |
0.581 |
-3.828 |
KIAA0174 |
KIAA0174 |
16 |
70486946 |
NM_014761 |
9798 |
16q22.2 |
Hs.232194 |
14 |
protein binding ER-Golgi intermediate compartment cell cycle cytoplasmic vesicle cell division |
|
210563_x_at |
0.642 |
8.039 |
2.447 |
2.698e-02 |
0.525 |
-3.393 |
CFLAR |
CASP8 and FADD-like apoptosis regulator |
2 |
201689060, 201689134, 201691631 |
U97075 |
8837 |
2q33-q34 |
Hs.390736 |
163 |
cysteine-type endopeptidase activity protein binding proteolysis anti-apoptosis induction of apoptosis by extracellular signals regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade interspecies interaction between organisms |
Apoptosis |
227317_at |
LMCD1 |
LIM and cysteine-rich domains 1 |
3 |
8518510 |
AA045042 |
29995 |
3p26-p24 |
Hs.475353 |
4 |
negative regulation of transcription from RNA polymerase II promoter molecular_function transcription corepressor activity protein binding cellular_component nucleus biological_process zinc ion binding metal ion binding |
|
214693_x_at |
NBPF10 |
neuroblastoma breakpoint family, member 10 |
1 |
144004727 |
BE732345 |
100132406 |
1q21.1 |
Hs.515947 |
6 |
cytoplasm |
|
1560399_a_at |
OTUD7A |
OTU domain containing 7A |
15 |
-29562620 |
BC035668 |
161725 |
15q13.3 |
Hs.355236 |
2 |
DNA binding nucleus cytoplasm peptidase activity cysteine-type peptidase activity zinc ion binding modification-dependent protein catabolic process metal ion binding |
|
1556414_at |
0.480 |
5.360 |
3.042 |
8.127e-03 |
0.387 |
-2.380 |
C21orf71 |
chromosome 21 open reading frame 71 |
21 |
-25876958 |
BU192089 |
282566 |
21q21.3 |
Hs.384586 |
|
|
|
222386_s_at |
0.251 |
8.732 |
2.325 |
3.428e-02 |
0.553 |
-3.593 |
COPZ1 |
coatomer protein complex, subunit zeta 1 |
12 |
53005177 |
AB047848 |
22818 |
12q13.2-q13.3 |
Hs.505652 |
14 |
protein binding cytoplasm Golgi apparatus cytosol intracellular protein transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport membrane membrane organization vesicle-mediated transport membrane coat COPI vesicle coat COPI vesicle coat cytoplasmic vesicle COPI coating of Golgi vesicle |
|
219481_at |
TTC13 |
tetratricopeptide repeat domain 13 |
1 |
-229108611 |
NM_024525 |
79573 |
1q42.2 |
Hs.424788 |
5 |
binding |
|
226370_at |
KLHL15 |
kelch-like 15 (Drosophila) |
X |
-23911756 |
BG149487 |
80311 |
Xp22.1-p21 |
Hs.495854 |
6 |
protein binding modification-dependent protein catabolic process |
|
214314_s_at |
EIF5B |
eukaryotic translation initiation factor 5B |
2 |
99320265 |
BE138647 |
9669 |
2q11.2 |
Hs.158688 |
15 |
nucleotide binding translation initiation factor activity translation initiation factor activity GTPase activity protein binding GTP binding cytoplasm translation regulation of translational initiation regulation of translational initiation |
|