| Primary Expertise |
| Dr. McGarvey has academic and commercial experience in molecular biology, biotechnology, bioinformatics and software development. He is interested in genomic and proteomic analysis, biological databases and data visualization. Dr. McGarvey currently works on large proteomics data sets and helps manage the NIAID Biodefense Proteomics Resource. In addition, he is a participant in the caBIG VCDE (Vocabulary and Common Data Elements) workspace and has led several caBIG adopter projects. |
| Education |
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B.S., Chemistry and Biomedical Sciences, Western Michigan University, Kalamazoo, MI. 1979 |
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Ph.D., Biological Sciences, The University of Michigan, Ann Arbor, MI. 1988 |
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M.S., Technology Management,University Maryland University College, College Park, MD. 2004 |
| Professional Activities |
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Member, American Association for the Advancement of Science. (1995-present). |
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Editor: Plant Biotechnology: New Products and Applications. Current Topics in Microbiology and Immunology Vol. 240, Springer-Verlag, New York, NY. (1999).
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Member Phytonutrient Review Panel, USDA Fund for Rural American (1997). |
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Institutional Biosafety Committee, Member, Thomas Jefferson University (1995-1998). |
| Publications |
McGarvey PB, Huang H, Mazumder R, Zhang J, Chen Y, Zhang C, Cammer S, Will R, Odle M, Sobral B, Moore M, Wu CH. 2009
Systems integration of biodefense omics data for analysis of pathogen-host interactions and identification of potential targets.
PLoS One. 2009 Sep 25;4(9):e7162. |
Jain, E., Bairoch, A., Duvaud, S., Phan, I., Redaschi, N., Martin, M.J., McGarvey, P.B., Suzek, B. and Gasteiger, E. 2009.
Infrastructure for the Life Sciences: Design and Implementation of the UniProt Website.
BMC-Bioinformatics 10:136 |
Zhang, C., Crasta, O., Cammer, S., Will, R., Kenyon, R., Sullivan, D., Yu, Q., Sun, W., Jha, R., Liu, D., Xue, T., Zhang, Y., Moore, M., McGarvey, P., Huang, H., Chen, Y., Zhang, J., Mazumder, R., Wu, C., Sobral, B., 2008. An emerging cyberinfrastructure for biodefense pathogen and pathogen host data. Nucleic Acids Res., 36:D884-D891. |
McGarvey, P., Huang, H., and Wu, C.H., 2007. Protein Bioinformatics.
Medical Applications of Mass Spectrometry. Vekey, K., Telekes, A., Vertes, A. (Eds.) Elsevier Science pp197-216. |
Suzek, B.E., Huang, H., McGarvey, P., Mazumder, R., Wu, C.H., 2007. UniRef: comprehensive and non-redundant UniProt reference clusters. Bioinformatics 23(10):1282-1288. |
Barker, W.C., Garavelli, J.S., Hou, Z., Huang, H., Ledley, R.S., McGarvey P.B., Mewes, H.W., Orcutt, B.C., Pfeiffer, F., Tsugita, A., Vinayaka, C.R., Xiao C., Yeh, L.S., Wu, C., 2001. Protein Information Resource: a community resource for expert annotation of protein data. Nucleic Acids Res. 29: 29-32. |
McGarvey, P.B., Huang, H., Barker, W.C., Orcutt, B.C., Garavelli, J.S., Srinivasarao, G.Y., Yeh, L-S.L., Xiao, C., and Wu., C.H., 2000. The PIR Web Site: New Resource for Bioinformatics. Bioinformatics 16: 290-291. |
Barker, W.C., Garavelli, J.S., Huang, H., McGarvey, P.B., Orcutt, B.C., Srinivasarao, G.Y., Xiao, C., Yeh, L-S.L., Ledley, R.S., Janda, J.F., Pfeiffer, F., Mewes, H-W., Tsugita, A., and Wu, C., 2000 The Protein Information Resource (PIR), Nucleic Acids Res., 28: 41-44. |
Barker W.C., Garavelli J.S., McGarvey, P.B. , Marzec, C.M., Orcutt, B.C., Srinivasarao, G.Y., Wu, C., Yeh, L.L., Ledley, R.S., Mewes, H-W, Pfeiffer, F., and Tsugita, A., 1999. The PIR-International Protein Sequence Database. Nucleic Acids Res. 27:39-43. |
Tousignant, M., McGarvey, P.B., Piazzolla P., and Kaper, J.M., 1996. Cucumber Mosaic Virus from Ixora: Infectious RNA transcripts confirm deficiency in satellite support and unusual symptomatology. Research in Virology 147: 363-373. |
McGarvey, P.B., Hammond, J., Dienelt, M.M., Hooper, D.C., Fu, Z.F., Dietzschold, B., Koprowski, H., and Michaels, F.H. 1995. Expression of the rabies virus glycoprotein in transgenic tomatoes. Nature BioTechnology 13: 1484-1487. |
Hooper, D.C., McGarvey, P.B., Conway, L., Dietzschold, B., Fu, Z.F., Modelska, A., DeBruin, S., Carlson, P.S., Michaels, F.H., and Koprowski, H. 1995. Prospects for oral vaccination against rabies virus. Proceedings of the Sixth Annual International Meeting on Research on Rabies Control in the Americas. |
McGarvey, P.B., Tousignant, M., Geletka, L., Cellini, F., and Kaper, J.M., 1995.
The complete sequence of a cucumber mosaic virus from Ixora that is deficient in the replication satellite RNAs. Journal of General Virology 76: 2257-2270.
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Peña L., Trad J., Díaz-Ruiz, J.R., McGarvey, P.B., and Kaper, J. M., 1994. Cucumber mosaic virus protection in transgenic tobacco plants expressing monomeric, dimeric, or partial sequences of a benign satellite RNA. Plant Science 100:71-81. |
McGarvey, P.B., Montasser, M., and Kaper, J.M., 1994. Transgenic tomato plants expressing satellite RNA are tolerant to some strains of cucumber mosaic virus. J. Amer. Soc. Hort. Sci. 119:642-647. |
McGarvey, P.B. and Kaper, J.M., 1992. Transgenic plants for conferring virus tolerance: satellite approach. In Transgenic Plants Vol. I. (Eds. Kung, S. and Wu, R.) pp. 277-296, Academic Press, Orlando Fl. |
McGarvey, P.B. and Kaper, J.M., 1991. A simple and rapid method for screening transgenic plants using the PCR. BioTechniques 11:428-432. |
McGarvey, P.B., Kaper, J.M., Avila-Rincon, M.J., Peņa L., and Díaz-Ruiz, J.R., 1990. Transformed tomato plants express a satellite of cucumber mosaic virus and produce lethal necrosis upon infection with viral RNA. Biochemical and Biophysical Research Communications 170:548-555. |
McGarvey, P.B., Helling, R.B., 1989. Processing of chloroplast ribosomal RNA transcripts in Euglena gracilis bacillaris. Current Genetics 15:363-370. |
McGarvey, P.B., Helling, R.B., Lee, J-Y, Engelke, D.R., and El-Gewely M.R., 1988. Initiation of rrn transcription in chloroplasts of Euglena gracilis bacillaris. Current Genetics 14:493-500. |
Vaught, J.B., McGarvey, P.B., Lee, M.L., Garner, C.D., Wang, C.Y., Linsmaier-Bednar, E.M., and King, C.M., 1981. Activation of n-hydroxyphenacitin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation. Cancer Research 42:3424-3429. |
Vaught, J.B., Shirai, T., McGarvey, P.B., and Savage, L., 1981. Ribonucleic acid-binding in rat liver hepatocytes treated with n-hydroxyphenacetin. Fed. Proc. 749. |
Revised 05/09/08
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